ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3599 good F KOG3222 Nucleotide transport and metabolism Inosine triphosphate pyrophosphatase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3599 1238253 1237672 -194
(194 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJR069c [F] KOG3222 Inosine triphosphate pyrophosphatase 247 8e-66
Hs15626999 [F] KOG3222 Inosine triphosphate pyrophosphatase 152 3e-37
7296918 [F] KOG3222 Inosine triphosphate pyrophosphatase 150 8e-37
CE25662 [F] KOG3222 Inosine triphosphate pyrophosphatase 142 2e-34
SPCC830.10 [F] KOG3222 Inosine triphosphate pyrophosphatase 133 2e-31
At4g13720 [F] KOG3222 Inosine triphosphate pyrophosphatase 133 2e-31
ECU04g1180 [F] KOG3222 Inosine triphosphate pyrophosphatase 92 3e-19
ECU05g0870 [F] KOG3222 Inosine triphosphate pyrophosphatase 70 2e-12
>YJR069c [F] KOG3222 Inosine triphosphate pyrophosphatase
Length = 197
Score = 247 bits (630), Expect = 8e-66
Identities = 130/194 (67%), Positives = 148/194 (76%), Gaps = 5/194 (2%)
Query: 1 MPKPEIVFVTGNANKLREVSMILGGDAS----PFTLVNEPLDLEELQGADLQEIALAKLQ 56
M EIVFVTGNANKL+EV IL + L+NE LDLEELQ DL IALAK +
Sbjct: 1 MSNNEIVFVTGNANKLKEVQSILTQEVDNNNKTIHLINEALDLEELQDTDLNAIALAKGK 60
Query: 57 QAVHALGPGRPVFVEDTALSFDEFNGLPGAYIKWFIKSMGLAKVVKMLDSFENKGAYAIT 116
QAV ALG G+PVFVEDTAL FDEFNGLPGAYIKWF+KSMGL K+VKML+ FENK A A+T
Sbjct: 61 QAVAALGKGKPVFVEDTALRFDEFNGLPGAYIKWFLKSMGLEKIVKMLEPFENKNAEAVT 120
Query: 117 TIAYADSKGQLHVFQGKTHGTIVDSRGHTNFGWDSIFQPDESQNNETYAEMAKEDKNKIS 176
TI +ADS+G+ H FQG T G IV SRG T FGWDSIF+P +S + TYAEM+K+ KN IS
Sbjct: 121 TICFADSRGEYHFFQGITRGKIVPSRGPTTFGWDSIFEPFDS-HGLTYAEMSKDAKNAIS 179
Query: 177 QRGRAFAQLKEYLY 190
RG+AFAQ KEYLY
Sbjct: 180 HRGKAFAQFKEYLY 193
>Hs15626999 [F] KOG3222 Inosine triphosphate pyrophosphatase
Length = 194
Score = 152 bits (384), Expect = 3e-37
Identities = 89/186 (47%), Positives = 118/186 (62%), Gaps = 8/186 (4%)
Query: 5 EIVFVTGNANKLREVSMILGGDASPFTLVNEPLDLEELQGADLQEIALAKLQQAVHALGP 64
+IVFVTGNA KL EV ILG D P TLV + +DL E QG + EI++ K Q+AV +
Sbjct: 9 KIVFVTGNAKKLEEVVQILG-DKFPCTLVAQKIDLPEYQG-EPDEISIQKCQEAVRQVQG 66
Query: 65 GRPVFVEDTALSFDEFNGLPGAYIKWFIKSMGLAKVVKMLDSFENKGAYAITTIAYA--D 122
PV VEDT L F+ GLPG YIKWF++ + + ++L FE+K AYA+ T A + D
Sbjct: 67 --PVLVEDTCLCFNALGGLPGPYIKWFLEKLKPEGLHQLLAGFEDKSAYALCTFALSTGD 124
Query: 123 SKGQLHVFQGKTHGTIVDSRGHTNFGWDSIFQPDESQNNETYAEMAKEDKNKISQRGRAF 182
+ +F+G+T G IV RG +FGWD FQPD + +TYAEM K +KN +S R RA
Sbjct: 125 PSQPVRLFRGRTSGRIVAPRGCQDFGWDPCFQPDGYE--QTYAEMPKAEKNAVSHRFRAL 182
Query: 183 AQLKEY 188
+L+EY
Sbjct: 183 LELQEY 188
>7296918 [F] KOG3222 Inosine triphosphate pyrophosphatase
Length = 191
Score = 150 bits (380), Expect = 8e-37
Identities = 88/189 (46%), Positives = 121/189 (63%), Gaps = 8/189 (4%)
Query: 1 MPKPEIVFVTGNANKLREVSMILGGDASPFTLVNEPLDLEELQGADLQEIALAKLQQAVH 60
M KP I FVTGNA KL E+ ILG + P T+V++ +DL ELQG D+ EIA+ K ++A
Sbjct: 1 MSKP-ITFVTGNAKKLEELVAILG-PSFPRTIVSKKIDLPELQG-DIDEIAIKKCKEAAR 57
Query: 61 ALGPGRPVFVEDTALSFDEFNGLPGAYIKWFIKSMGLAKVVKMLDSFENKGAYAITTIAY 120
+ PV VEDT+L F+ GLPG YIKWF++ + + ++L +ENK A AI T Y
Sbjct: 58 QVNG--PVLVEDTSLCFNALEGLPGPYIKWFLEKLQPEGLHRLLHGWENKSAQAICTFGY 115
Query: 121 ADS-KGQLHVFQGKTHGTIVDSRGHTNFGWDSIFQPDESQNNETYAEMAKEDKNKISQRG 179
D + +F+G T G IV+ RG +FGWD +FQP S ++TYAE+ K +KN IS R
Sbjct: 116 CDGVDAEPLIFKGITEGVIVEPRGPRDFGWDPVFQP--SGYDKTYAELPKSEKNTISHRY 173
Query: 180 RAFAQLKEY 188
RA A L+++
Sbjct: 174 RALALLRQH 182
>CE25662 [F] KOG3222 Inosine triphosphate pyrophosphatase
Length = 184
Score = 142 bits (359), Expect = 2e-34
Identities = 88/188 (46%), Positives = 112/188 (58%), Gaps = 10/188 (5%)
Query: 5 EIVFVTGNANKLREVSMILGGDASPFTLVNEPLDLEELQGADLQEIALAKLQQAVHALGP 64
+I FVTGN KL EV IL F + N +DL+E QG + + IA K ++AV A+
Sbjct: 5 KINFVTGNVKKLEEVKAILKN----FEVSNVDVDLDEFQG-EPEFIAERKCREAVEAVKG 59
Query: 65 GRPVFVEDTALSFDEFNGLPGAYIKWFIKSMGLAKVVKMLDSFENKGAYAITTIAYADSK 124
PV VEDT+L F+ GLPG YIKWF+K++ + ML F +K AYA AY +
Sbjct: 60 --PVLVEDTSLCFNAMGGLPGPYIKWFLKNLKPEGLHNMLAGFSDKTAYAQCIFAYTEGL 117
Query: 125 GQ-LHVFQGKTHGTIVDSRGHTNFGWDSIFQPDESQNNETYAEMAKEDKNKISQRGRAFA 183
G+ +HVF GK G IV RG T FGWD FQPD + ET+ EM K+ KN+IS R +A
Sbjct: 118 GKPIHVFAGKCPGQIVAPRGDTAFGWDPCFQPDGFK--ETFGEMDKDVKNEISHRAKALE 175
Query: 184 QLKEYLYN 191
LKEY N
Sbjct: 176 LLKEYFQN 183
>SPCC830.10 [F] KOG3222 Inosine triphosphate pyrophosphatase
Length = 188
Score = 133 bits (334), Expect = 2e-31
Identities = 76/185 (41%), Positives = 110/185 (59%), Gaps = 9/185 (4%)
Query: 6 IVFVTGNANKLREVSMILGGDASPFTLVNEPLDLEELQGADLQEIALAKLQQAVHALGPG 65
I+FVTGN +KL +V ILG F + N DL E+QG+ ++E+ L K + A +
Sbjct: 7 ILFVTGNKHKLADVKNILG---DRFEIKNHDYDLPEIQGS-VKEVVLEKCKAAAEIVKG- 61
Query: 66 RPVFVEDTALSFDEFNGLPGAYIKWFIKSMGLAKVVKMLDSFENKGAYAITTIAYADSKG 125
PV VEDT L + NGLPG Y+KWF+ S+G + +M+ +F+ K A A T Y G
Sbjct: 62 -PVLVEDTWLGYKAMNGLPGPYVKWFLNSVGPDGLYRMVSAFDTKEAQAGCTFGYTKGPG 120
Query: 126 Q-LHVFQGKTHGTIVDSRGHTNFGWDSIFQPDESQNNETYAEMAKEDKNKISQRGRAFAQ 184
+ +H+F+G G +V RG FGW+SIFQP + + TYAEM E++N S R A +
Sbjct: 121 KPIHLFEGILDGQVVPPRGSNGFGWNSIFQP--NGHKHTYAEMTDEERNSCSHRYLAAMK 178
Query: 185 LKEYL 189
L+++L
Sbjct: 179 LRDFL 183
>At4g13720 [F] KOG3222 Inosine triphosphate pyrophosphatase
Length = 231
Score = 133 bits (334), Expect = 2e-31
Identities = 85/219 (38%), Positives = 120/219 (53%), Gaps = 35/219 (15%)
Query: 1 MPKPEIVFVTGNANKLREVSMILGGDASPFT-----------------LVNEPLDLEELQ 43
+P+P + FVTGNA KL EV I+G ++ PF L EP D+ + +
Sbjct: 12 LPRP-VTFVTGNAKKLEEVKAIIG-NSIPFKSLKLDCALIVYFLAVPELQGEPEDISKEK 69
Query: 44 GADLQEIA--------LAKLQQAVHALGPGRPVFVEDTALSFDEFNGLPGAYIKWFIKSM 95
L E+ + KL V PV VEDT L F+ GLPG YIKWF++ +
Sbjct: 70 AHILLELITKVIIFVFMCKLASYVDG-----PVLVEDTCLCFNALKGLPGPYIKWFLEKL 124
Query: 96 GLAKVVKMLDSFENKGAYAITTIAYADSKG-QLHVFQGKTHGTIVDSRGHTNFGWDSIFQ 154
G + +L ++E+K AYA+ +++ G + F GKT G IV +RG T+FGWD +FQ
Sbjct: 125 GHEGLNNLLMAYEDKSAYALCAFSFSRGPGAEPLTFLGKTPGKIVPARGPTDFGWDPVFQ 184
Query: 155 PDESQNNETYAEMAKEDKNKISQRGRAFAQLKEYLYNTG 193
PD ++TYAEMAKE+KNKIS R ++ A +K + G
Sbjct: 185 PD--GYDQTYAEMAKEEKNKISHRYKSLALVKSHFKEAG 221
>ECU04g1180 [F] KOG3222 Inosine triphosphate pyrophosphatase
Length = 192
Score = 92.4 bits (228), Expect = 3e-19
Identities = 64/192 (33%), Positives = 102/192 (52%), Gaps = 12/192 (6%)
Query: 6 IVFVTGNANKLREVSMILGGDASPFTLVNEPLDLEELQGADLQEIALAKLQQAVHALGPG 65
I F T N KL+E+ + D +V+ + + E+Q A L+ I KL Q V +G G
Sbjct: 4 IYFATTNLKKLKEIRSLFEAD-----IVHMNIPMVEIQ-ASLERIVDHKLNQVVPCIGEG 57
Query: 66 RPVFVEDTALSFDEFNGLPGAYIKWFIKSMGLAKVVKMLDSFENKGAYAITTIA---YAD 122
V V+DTA++F+ G PG YIK F++ +G K+ +++ N A A + Y D
Sbjct: 58 DAVIVDDTAVAFEGLYGFPGVYIKDFLR-IGSRKISEIVGKIGNSNATAFCCLGIAHYRD 116
Query: 123 SKGQLHVFQGKTHGTIVDSRGHTNFGWDSIFQPDESQNNETYAEMAKEDKNKISQRGRAF 182
+ VF G+ G+IV+S+ G+D IF P S ++ +M ++KN+IS R A
Sbjct: 117 GRVVKKVFFGELEGSIVESKEDGLEGFDYIFLP--SGSSMCLGDMPVDEKNRISHRRIAS 174
Query: 183 AQLKEYLYNTGI 194
+L +Y+ + GI
Sbjct: 175 KKLADYMASVGI 186
>ECU05g0870 [F] KOG3222 Inosine triphosphate pyrophosphatase
Length = 224
Score = 69.7 bits (169), Expect = 2e-12
Identities = 55/190 (28%), Positives = 95/190 (49%), Gaps = 13/190 (6%)
Query: 7 VFVTGNANKLREVSMILGGDASPFTLVNEPLDLEELQGADLQEIALAKLQQAVHALGPGR 66
+F+T ++ K + LG +P ++ LD+EE+QG+ +EI + KLQ+ H +
Sbjct: 39 LFITSSSYKYKAFQEFLG---APVQMIR--LDIEEIQGSK-EEIIIDKLQKVSHLVTEST 92
Query: 67 PVFVEDTALSFDEFNGLPGAYIKWFIKSMGLAKVVKMLDSFENKGAYAITTIAYADSKGQ 126
VFV+DT++ G PG Y K F+K MG +V+++ + Y+ KG+
Sbjct: 93 FVFVDDTSIHMSGLGGFPGQYAKDFLK-MGAPRVLEVASKVGGECVYSTIIGVVHMHKGK 151
Query: 127 L--HVFQGKTHGTIVDSRGHTNFGWDSIFQPDESQNNETYAEMAKEDKNKISQRGRAFAQ 184
+ F G+ HG+I+ G + +F +E +++E +A KI R RA +
Sbjct: 152 MVTRTFAGEVHGSIMPRDGVKPEIFSDLFTAEEDEHDEMPHGIA---GIKIG-RYRAVEK 207
Query: 185 LKEYLYNTGI 194
+K YL G+
Sbjct: 208 VKRYLAEIGV 217
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.135 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,915,856
Number of Sequences: 60738
Number of extensions: 495602
Number of successful extensions: 1109
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1081
Number of HSP's gapped (non-prelim): 8
length of query: 194
length of database: 30,389,216
effective HSP length: 101
effective length of query: 93
effective length of database: 24,254,678
effective search space: 2255685054
effective search space used: 2255685054
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)