ORF      STATUS       Function Best COG  Functional category                                          Pathways and functional systems
r_klactII3629   good          I     KOG4142  Lipid transport and metabolism                                 Phospholipid methyltransferase

BLASTP 2.2.3 [May-13-2002]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= r_klactII3629 1247831 1247178 -218 
         (218 letters)

Database: KOG eukaryal database 04/03 
           60,738 sequences; 30,389,216 total letters

Searching..................................................done

Color Key for Alignment Scores:   


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

YJR073c [I] KOG4142 Phospholipid methyltransferase                    253   1e-67
SPBC337.16 [I] KOG4142 Phospholipid methyltransferase                 192   3e-49
Hs6005828 [I] KOG4142 Phospholipid methyltransferase                  167   1e-41

>YJR073c [I] KOG4142 Phospholipid methyltransferase
          Length = 206

 Score =  253 bits (647), Expect = 1e-67
 Identities = 118/189 (62%), Positives = 150/189 (78%)

Query: 20  EIVTLTNFESREYTIALGLIAFNPIFWNVVARLEHSTHFLTKIAGSAKRGCYFLAATIFS 79
           +++   + +S ++ +A+    FNPIFWN+VAR+E+  H LTK+ G A++GCY LAATIFS
Sbjct: 11  QLIHSVDLQSSKFQLAIVCTMFNPIFWNIVARMEYHKHSLTKMCGGARKGCYMLAATIFS 70

Query: 80  LGIIRDYFYESALRQQPVSAMMTGDKFTYVGIAYIAFGQLLVLSSMYQLGITGTYLGDYF 139
           LGI+RD  YESALR+QP  +++TG+ +T +G+A    GQ+LVLSSMY+LGITGTYLGDYF
Sbjct: 71  LGIVRDMVYESALREQPTCSLITGENWTKLGVALFGLGQVLVLSSMYKLGITGTYLGDYF 130

Query: 140 GILMDHRVTSFPFNYFDNPMYQGSTFTFLGYALYNGKPAGLIATLVVHVMYNIALRFEEP 199
           GILMD RVT FPFN  +NPMYQGST +FLG ALY GKPAGL+ + VV+ MY IALR+EEP
Sbjct: 131 GILMDERVTGFPFNVSNNPMYQGSTLSFLGIALYKGKPAGLVVSAVVYFMYKIALRWEEP 190

Query: 200 FTAKIYAKR 208
           FTA IYA R
Sbjct: 191 FTAMIYANR 199


>SPBC337.16 [I] KOG4142 Phospholipid methyltransferase
          Length = 221

 Score =  192 bits (488), Expect = 3e-49
 Identities = 98/188 (52%), Positives = 123/188 (65%), Gaps = 1/188 (0%)

Query: 29  SREYTIALGLIAFNPIFWNVVARLEHSTHFLTKIA-GSAKRGCYFLAATIFSLGIIRDYF 87
           +  + I    IA NP+ WN+ AR E++   LTK+A G +K+ CY LAA IF  GI+RD  
Sbjct: 32  NNSFLICAVSIALNPLLWNIAARSEYNHKTLTKLANGDSKKACYMLAACIFVAGIVRDLI 91

Query: 88  YESALRQQPVSAMMTGDKFTYVGIAYIAFGQLLVLSSMYQLGITGTYLGDYFGILMDHRV 147
           Y++AL+QQP   +        +      FG +LVLSSMY+LG+ GTYLGDYFG L+  RV
Sbjct: 92  YQNALKQQPTLGIFMNPLVQGIAKLIFCFGSVLVLSSMYKLGLVGTYLGDYFGFLLPERV 151

Query: 148 TSFPFNYFDNPMYQGSTFTFLGYALYNGKPAGLIATLVVHVMYNIALRFEEPFTAKIYAK 207
           + FPFN  DNPMY GST  FL  AL  GK AGL+ TL V  +Y IAL+FEEPFTAKIYA 
Sbjct: 152 SGFPFNVNDNPMYNGSTLCFLSTALRYGKVAGLLLTLEVFFVYRIALKFEEPFTAKIYAA 211

Query: 208 RAAEDANK 215
           R ++ A K
Sbjct: 212 RDSKQAKK 219


>Hs6005828 [I] KOG4142 Phospholipid methyltransferase
          Length = 199

 Score =  167 bits (423), Expect = 1e-41
 Identities = 82/179 (45%), Positives = 115/179 (63%)

Query: 32  YTIALGLIAFNPIFWNVVARLEHSTHFLTKIAGSAKRGCYFLAATIFSLGIIRDYFYESA 91
           +  A+  I FNP++WNVVAR EH T  L++  GS    CY L+ TI  L  +R + +  A
Sbjct: 15  FVAAVITITFNPLYWNVVARWEHKTRKLSRAFGSPYLACYSLSITILLLNFLRSHCFTQA 74

Query: 92  LRQQPVSAMMTGDKFTYVGIAYIAFGQLLVLSSMYQLGITGTYLGDYFGILMDHRVTSFP 151
           +  QP    +       +G+A +  G +LVLSS + LG  GT+LGDYFGIL + RVT FP
Sbjct: 75  MLSQPRMESLDTPAAYSLGLALLGLGVVLVLSSFFALGFAGTFLGDYFGILKEARVTVFP 134

Query: 152 FNYFDNPMYQGSTFTFLGYALYNGKPAGLIATLVVHVMYNIALRFEEPFTAKIYAKRAA 210
           FN  DNPMY GST  +LG+A+ +  P GL+ T++V + Y +AL +EEPFTA+IY ++A+
Sbjct: 135 FNILDNPMYWGSTANYLGWAIMHASPTGLLLTVLVALTYIMALLYEEPFTAEIYRQKAS 193


  Database: KOG eukaryal database 04/03
    Posted date:  Apr 14, 2003  1:07 PM
  Number of letters in database: 30,389,216
  Number of sequences in database:  60,738
  
Lambda     K      H
   0.327    0.142    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,159,677
Number of Sequences: 60738
Number of extensions: 485276
Number of successful extensions: 1084
Number of sequences better than 1.0e-05: 3
Number of HSP's better than  0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1079
Number of HSP's gapped (non-prelim): 3
length of query: 218
length of database: 30,389,216
effective HSP length: 102
effective length of query: 116
effective length of database: 24,193,940
effective search space: 2806497040
effective search space used: 2806497040
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)