ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3643 check: MH O KOG2012 Posttranslational modification, protein turnover, chaperones Ubiquitin activating enzyme UBA1
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3643 1255655 1252599 -1019
(1019 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL210w [O] KOG2012 Ubiquitin activating enzyme UBA1 1628 0.0
Hs4507763 [O] KOG2012 Ubiquitin activating enzyme UBA1 1031 0.0
7303864 [O] KOG2012 Ubiquitin activating enzyme UBA1 965 0.0
At5g06460 [O] KOG2012 Ubiquitin activating enzyme UBA1 868 0.0
At2g30110 [O] KOG2012 Ubiquitin activating enzyme UBA1 865 0.0
CE05449 [O] KOG2012 Ubiquitin activating enzyme UBA1 761 0.0
SPBC211.09 [O] KOG2012 Ubiquitin activating enzyme UBA1 756 0.0
Hs21361718 [O] KOG2012 Ubiquitin activating enzyme UBA1 690 0.0
Hs4507767 [O] KOG2012 Ubiquitin activating enzyme UBA1 632 0.0
ECU03g0930 [O] KOG2012 Ubiquitin activating enzyme UBA1 602 e-172
HsM8922684 [O] KOG2012 Ubiquitin activating enzyme UBA1 291 4e-78
At2g21470 [O] KOG2013 SMT3/SUMO-activating complex catalytic com... 175 3e-43
Hs4885649 [O] KOG2013 SMT3/SUMO-activating complex catalytic com... 166 2e-40
7295159_1 [O] KOG2013 SMT3/SUMO-activating complex catalytic com... 165 3e-40
SPBC16H5.03c [O] KOG2013 SMT3/SUMO-activating complex catalytic ... 157 8e-38
YDR390c [O] KOG2013 SMT3/SUMO-activating complex catalytic compo... 150 1e-35
Hs19923744 [O] KOG2015 NEDD8-activating complex catalytic compon... 122 2e-27
CE25131 [O] KOG2013 SMT3/SUMO-activating complex catalytic compo... 122 2e-27
CE25130 [O] KOG2013 SMT3/SUMO-activating complex catalytic compo... 118 4e-26
Hs4885585 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 co... 116 2e-25
7303261 [O] KOG2015 NEDD8-activating complex catalytic component... 113 2e-24
At5g19180 [O] KOG2015 NEDD8-activating complex catalytic compone... 105 4e-22
SPAC24H6.12c [O] KOG2015 NEDD8-activating complex catalytic comp... 103 1e-21
ECU02g1340 [O] KOG2013 SMT3/SUMO-activating complex catalytic co... 103 2e-21
CE04374 [O] KOG2015 NEDD8-activating complex catalytic component... 103 2e-21
YPR066w [O] KOG2015 NEDD8-activating complex catalytic component... 101 5e-21
SPAC4C5.04 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 c... 96 3e-19
YPR180w [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 comp... 92 5e-18
7299631 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 comp... 86 3e-16
At5g50680 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 co... 75 5e-13
At5g50580 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 co... 75 5e-13
CE05246 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 comp... 75 7e-13
CE01166 [O] KOG2016 NEDD8-activating complex APP-BP1/UBA5 component 75 7e-13
CE28320 [H] KOG2017 Molybdopterin synthase sulfurylase 74 1e-12
Hs20559018 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 c... 73 2e-12
At4g24940 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 co... 72 6e-12
At1g05180 [O] KOG2016 NEDD8-activating complex APP-BP1/UBA5 comp... 71 1e-11
At2g32410 [O] KOG2016 NEDD8-activating complex APP-BP1/UBA5 comp... 70 2e-11
Hs4502169 [O] KOG2016 NEDD8-activating complex APP-BP1/UBA5 comp... 67 2e-10
At5g55130 [H] KOG2017 Molybdopterin synthase sulfurylase 66 3e-10
YHR111w [H] KOG2017 Molybdopterin synthase sulfurylase 65 4e-10
At1g05350 [H] KOG2336 Molybdopterin biosynthesis-related protein 64 1e-09
7297432 [H] KOG2017 Molybdopterin synthase sulfurylase 63 2e-09
SPAC2G11.10c [H] KOG2017 Molybdopterin synthase sulfurylase 60 2e-08
CE13096 [H] KOG2336 Molybdopterin biosynthesis-related protein 59 4e-08
At5g37530 [O] KOG2018 Predicted dinucleotide-utilizing enzyme in... 57 1e-07
SPAC323.06c [O] KOG2016 NEDD8-activating complex APP-BP1/UBA5 co... 57 2e-07
SPAC1A6.10 [O] KOG2018 Predicted dinucleotide-utilizing enzyme i... 57 2e-07
Hs13376212 [H] KOG2336 Molybdopterin biosynthesis-related protein 56 3e-07
Hs7657339 [H] KOG2017 Molybdopterin synthase sulfurylase 55 7e-07
7294767 [O] KOG2016 NEDD8-activating complex APP-BP1/UBA5 component 54 2e-06
>YKL210w [O] KOG2012 Ubiquitin activating enzyme UBA1
Length = 1024
Score = 1628 bits (4216), Expect = 0.0
Identities = 791/1012 (78%), Positives = 910/1012 (89%), Gaps = 2/1012 (0%)
Query: 10 EIDESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVA 69
EIDESLYSRQLYVLGKEAMLKMQ SNVLI+GLKGLGVEIAKNVVLAGVKS+T++DP V
Sbjct: 13 EIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQ 72
Query: 70 LQDLSTQFFLSEQDIGQARDKVSQAKLAELNSYVPVKVLEGLEDVSQLSEFQVVVVTDTI 129
L DLSTQFFL+E+DIGQ R V++AKLAELN+YVPV VL+ L+DV+QLS+FQVVV TDT+
Sbjct: 73 LADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTV 132
Query: 130 SLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDTTGEEPKTGIVSDIESD 189
SLE+KVK+NE+ HS GI FIS+ETRGLFGN FVDLG+EFTV+D TGEEP+TG+VSDIE D
Sbjct: 133 SLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPD 192
Query: 190 GTVTMLDDNRHGLEDGNYVKFSEVEGLEKLNDGTPYKVEVLGPFAFKIGSVKDLGTYKKG 249
GTVTMLDDNRHGLEDGN+V+FSEVEGL+KLNDGT +KVEVLGPFAF+IGSVK+ G YKKG
Sbjct: 193 GTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKG 252
Query: 250 GLFTEVKMPQKLTFKSLRESLATPEFLYSDFAKFETTAQLHLGFQALHQFQVRHQGELPR 309
G+FTEVK+P+K++FKSL++ L+ PEF++SDFAKF+ AQLHLGFQALHQF VRH GELPR
Sbjct: 253 GIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPR 312
Query: 310 PFYEEDSNELVKLVIDLATQQPEVLGSEGKVDEKLITELANQARGDIPGIVAFFGGLVAQ 369
+ED+NEL+KLV DL+ QQPEVLG V+E LI EL+ QARGDIPG+VAFFGGLVAQ
Sbjct: 313 TMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQ 372
Query: 370 EVLKASSGKFTPIKQYMYFDSIESLPDSEDFPRNADTTKPINSRYDNQISVFGLEFQKRI 429
EVLKA SGKFTP+KQ+MYFDS+ESLPD ++FPRN TT+P+NSRYDNQI+VFGL+FQK+I
Sbjct: 373 EVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKI 432
Query: 430 ANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKDVGR 489
AN KVFLVGSGAIGCEMLKNWALLGL SG +G I+VTDNDSIEKSNLNRQFLFRPKDVG+
Sbjct: 433 ANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGK 492
Query: 490 NKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNALDNVDARTYV 549
NKSEVAA+AV AMNPDLKGKI KIDKVG ETE IFND+FW LDFVTNALDNVDARTYV
Sbjct: 493 NKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYV 552
Query: 550 DRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEKSIPLCTLRSFPNKIDHT 609
DRRCVFY+KPLLESGTLGTKGNTQV+IP LTESYSSSRDPPEKSIPLCTLRSFPNKIDHT
Sbjct: 553 DRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHT 612
Query: 610 IAWAKSLFQGYFSDAAENVNLYLTQPNFVEQTLKQAPDAKGILESISDCLNNRPYNFEDC 669
IAWAKSLFQGYF+D+AENVN+YLTQPNFVEQTLKQ+ D KG+LESISD L+++P+NFEDC
Sbjct: 613 IAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKQSGDVKGVLESISDSLSSKPHNFEDC 672
Query: 670 VKWARLEFEKKFSYDIQQFLYNFPKDATTSTGEPFWSGPKRAPEPLVFNIENPDHFHFIV 729
+KWARLEFEKKF++DI+Q L+NFPKDA TS GEPFWSG KRAP PL F+I N DHFHF+V
Sbjct: 673 IKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVV 732
Query: 730 ASANLRAFNYGLKGDD--GKPDINYYQSVLSKLIVPEFIPKADIKIQTNDDEPDPNANNQ 787
A A+LRA+NYG+K DD KP+++ Y+SV+ +I+PEF P A++KIQ NDD+PDPNAN
Sbjct: 733 AGASLRAYNYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDDDPDPNANAA 792
Query: 788 LGGDVLENLAASLPDASTLAGFQLIPVEFEKDDDTNHHIEFITAASNNRALNYSIEPADR 847
G D ++ L +SLPD STLAGF+L PV+FEKDDDTNHHIEFITA SN RA NY IE ADR
Sbjct: 793 NGSDEIDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADR 852
Query: 848 QKTKFIAGRIIPAIATTTALVTGLVNLELYKVVAGKTDIEQYKNGFVNLALPFFGFSEPI 907
QKTKFIAGRIIPAIATTT+LVTGLVNLELYK++ KTDIEQYKNGFVNLALPFFGFSEPI
Sbjct: 853 QKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPI 912
Query: 908 ASQKGKYNDKTFDKIWDRFDIQGDITLRELIDHFNKEEGLEITMVSYDVSLLYASFFPPK 967
AS KG+YN+K +DKIWDRFDI+GDI L +LI+HF K+EGLEITM+SY VSLLYASFFPPK
Sbjct: 913 ASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPK 972
Query: 968 KLKDRMDLPITEVVKLVTKKEILSHVKTMILEFCCEDKEGEDVEVPYVTVHL 1019
KLK+R++LPIT++VKLVTKK+I +HV TMILE C +DKEGEDVEVP++T+HL
Sbjct: 973 KLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL 1024
>Hs4507763 [O] KOG2012 Ubiquitin activating enzyme UBA1
Length = 1058
Score = 1031 bits (2666), Expect = 0.0
Identities = 538/1017 (52%), Positives = 717/1017 (69%), Gaps = 23/1017 (2%)
Query: 10 EIDESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVA 69
+IDE LYSRQLYVLG EAM ++Q S+VL+ GL+GLGVEIAKN++L GVK++TL+D
Sbjct: 49 DIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQ 108
Query: 70 LQDLSTQFFLSEQDIGQARDKVSQAKLAELNSYVPVKVLEGLEDVSQLSEFQVVVVTDTI 129
DLS+QF+L E+DIG+ R +VSQ +LAELNSYVPV G LS FQVVV+T+T
Sbjct: 109 WADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNT- 167
Query: 130 SLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDTTGEEPKTGIVSDIESD 189
LE+++++ E+ H+ GI + TRGLFG +F D GEE + D+ GE+P + +VS + D
Sbjct: 168 PLEDQLRVGEFCHNRGIKLVVAGTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKD 227
Query: 190 --GTVTMLDDNRHGLEDGNYVKFSEVEGLEKLNDGTPYKVEVLGPFAFKIGSVKDLGTYK 247
G VT LD+ RHG E G++V FSEV+G+ +LN P +++VLGP+ F I + Y
Sbjct: 228 NPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYI 287
Query: 248 KGGLFTEVKMPQKLTFKSLRESLATPEFLYSDFAKFETTAQLHLGFQALHQFQVRHQGEL 307
+GG+ ++VK+P+K++FKSL SLA P+F+ +DFAKF AQLH+GFQALHQF +H G
Sbjct: 288 RGGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCAQH-GRP 346
Query: 308 PRPFYEEDSNELVKLVIDL-ATQQPEVLGSEGKVDEKLITELANQARGDIPGIVAFFGGL 366
PRP EED+ ELV L + A P V + +DE LI +LA A GD+ I AF GGL
Sbjct: 347 PRPRNEEDAAELVALAQAVNARALPAV--QQNNLDEDLIRKLAYVAAGDLAPINAFIGGL 404
Query: 367 VAQEVLKASSGKFTPIKQYMYFDSIESLPDSEDFPRNADTTKPINSRYDNQISVFGLEFQ 426
AQEV+KA SGKF PI Q++YFD++E LP ++ D +RYD Q++VFG + Q
Sbjct: 405 AAQEVMKACSGKFMPIMQWLYFDALECLPQDKEV-LTEDKCLQRQNRYDGQVAVFGSDLQ 463
Query: 427 KRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKD 486
+++ K FLVG+GAIGCE+LKN+A++GL G G+IIVTD D+IEKSNLNRQFLFRP D
Sbjct: 464 EKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWD 523
Query: 487 VGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNALDNVDAR 546
V + KS+ AA AV MNP ++ + ++VG +TE I++D F+ LD V NALDNVDAR
Sbjct: 524 VTKLKSDTAAAAVRQMNPHIR--VTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDAR 581
Query: 547 TYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEKSIPLCTLRSFPNKI 606
Y+DRRCV+Y+KPLLESGTLGTKGN QVVIP LTESYSSS+DPPEKSIP+CTL++FPN I
Sbjct: 582 MYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAI 641
Query: 607 DHTIAWAKSLFQGYFSDAAENVNLYLTQPNFVEQTLKQA-PDAKGILESISDCL-NNRPY 664
+HT+ WA+ F+G F AENVN YLT P FVE+TL+ A +LE++ L RP
Sbjct: 642 EHTLQWARDEFEGLFKQPAENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQ 701
Query: 665 NFEDCVKWARLEFEKKFSYDIQQFLYNFPKDATTSTGEPFWSGPKRAPEPLVFNIENPDH 724
+ DCV WA + ++S +I+Q L+NFP D TS+G PFWSGPKR P PL F++ NP H
Sbjct: 702 TWADCVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNPLH 761
Query: 725 FHFIVASANLRAFNYGLKGDDGKPDINYYQSVLSKLIVPEFIPKADIKIQTNDDEPDPNA 784
+++A+ANL A YGL G + + + L + VPEF PK+ +KI +D E +A
Sbjct: 762 LDYVMAAANLFAQTYGLTGSQDRAAV---ATFLQSVQVPEFTPKSGVKIHVSDQELQ-SA 817
Query: 785 NNQLGGDVLENLAASLPDASTLAGFQLIPVEFEKDDDTNHHIEFITAASNNRALNYSIEP 844
N + LE L A+LP L GF++ P++FEKDDD+N H++FI AASN RA NY I
Sbjct: 818 NASVDDSRLEELKATLPSPDKLPGFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPS 877
Query: 845 ADRQKTKFIAGRIIPAIATTTALVTGLVNLELYKVVAGKTDIEQYKNGFVNLALPFFGFS 904
ADR K+K IAG+IIPAIATTTA V GLV LELYKVV G ++ YKNGF+NLALPFFGFS
Sbjct: 878 ADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFS 937
Query: 905 EPIASQKGKYNDKTFDKIWDRFDIQG------DITLRELIDHFNKEEGLEITMVSYDVSL 958
EP+A+ + +Y ++ + +WDRF++QG ++TL++ +D+F E LEITM+S VS+
Sbjct: 938 EPLAAPRHQYYNQEW-TLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSM 996
Query: 959 LYASFFPPKKLKDRMDLPITEVVKLVTKKEILSHVKTMILEFCCEDKEGEDVEVPYV 1015
LY+ F P KLK+R+D P+TE+V V+K+++ HV+ ++LE CC D+ GEDVEVPYV
Sbjct: 997 LYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYV 1053
>7303864 [O] KOG2012 Ubiquitin activating enzyme UBA1
Length = 1008
Score = 965 bits (2495), Expect = 0.0
Identities = 500/1021 (48%), Positives = 705/1021 (68%), Gaps = 29/1021 (2%)
Query: 3 NIKVDGEEIDESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTL 62
N G +IDESLYSRQLYVLG +AM +M +S++L+ GL GLG+EIAKNV+L GVKS+TL
Sbjct: 4 NSAAAGGDIDESLYSRQLYVLGHDAMRRMANSDILLSGLGGLGLEIAKNVILGGVKSITL 63
Query: 63 YDPSAVALQDLSTQFFLSEQDIGQARDKVSQAKLAELNSYVPVKVLEGLEDVSQLSEFQV 122
+D + L DLS+QF+L+E DIG+ R + S A+LAELN+YV G L +F+V
Sbjct: 64 HDTATCGLHDLSSQFYLTEADIGKNRAEASCAQLAELNNYVRTVSHTGPLTEEFLRKFRV 123
Query: 123 VVVTDTISLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDTTGEEPKTGI 182
VV+T++ EE+ ++ ++ H +GI I ETRGLF VF D GE FT+ D G +P + +
Sbjct: 124 VVLTNSDG-EEQQRIAKFAHENGIALIIAETRGLFAKVFCDFGESFTIYDQDGTQPISTM 182
Query: 183 VSDIESD--GTVTMLDDNRHGLEDGNYVKFSEVEGLEKLNDGTPYKVEVLGPFAFKIGSV 240
++ I D G VT LD+ RHG DG+YV FSEV+G+++LN P K+ VLGP+ F IG
Sbjct: 183 IASITHDAQGVVTCLDETRHGFNDGDYVTFSEVQGMQELNGCQPLKITVLGPYTFSIGDT 242
Query: 241 KDLGTYKKGGLFTEVKMPQKLTFKSLRESLATPEFLYSDFAKFETTAQLHLGFQALHQFQ 300
G YK GG+ T+VKMP+ ++FK L ++ PEFL SDFAK ++ A LH+ F AL ++
Sbjct: 243 SKFGEYKSGGVATQVKMPKTISFKPLAQATEEPEFLISDFAKLDSPATLHVAFNALSCYR 302
Query: 301 VRHQGELPRPFYEEDSNELVKLVIDLATQQPEVLGSEGKVDEKLITELANQARGDIPGIV 360
H G LPRP+ EED+N +++V S +VDEKL+ + A G+ +
Sbjct: 303 KAHNGALPRPWNEEDANSFLEVVR---------ASSNAEVDEKLVLQFAKICSGNTCPLD 353
Query: 361 AFFGGLVAQEVLKASSGKFTPIKQYMYFDSIESLPDSEDFPRNADTTKPINSRYDNQISV 420
A GG+VAQEVLKA SGKFTPI Q++YFD++E LP + AD +P+ SRYD+QI++
Sbjct: 354 AAVGGIVAQEVLKACSGKFTPIYQWLYFDALECLPT--EGVEEADA-QPVGSRYDSQIAI 410
Query: 421 FGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQF 480
FG +FQ+++A+ K F+VG+GAIGCE+LKN+ +LGL +G G+I VTD D IEKSNLNRQF
Sbjct: 411 FGKKFQEKLADSKWFIVGAGAIGCELLKNFGMLGLGTG-NGQIFVTDMDLIEKSNLNRQF 469
Query: 481 LFRPKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNAL 540
LFRP DV + KS AADA+ MNP++ + +VGAETE +F++ F+ +LD V NAL
Sbjct: 470 LFRPHDVQKPKSMTAADAIKRMNPEVN--VTAYELRVGAETEKVFSEDFFGKLDGVANAL 527
Query: 541 DNVDARTYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEKSIPLCTLR 600
DNVDAR Y+DR+C+F + PL+E+GTLGT GN QV++P TESYSSS+DPPEKSIP+CTL+
Sbjct: 528 DNVDARIYMDRKCIFNRIPLVETGTLGTLGNVQVIVPFATESYSSSQDPPEKSIPICTLK 587
Query: 601 SFPNKIDHTIAWAKSLFQGYFSDAAENVNLYLTQPNFVEQTLK-QAPDAKGILESISDCL 659
+FPN I+HT+ WA+ F+G F +AEN Y+ P F E+ K IL+SI L
Sbjct: 588 NFPNAIEHTLQWARDAFEGVFKQSAENAAQYIADPQFTERIAKLPGIQPLEILDSIKKAL 647
Query: 660 -NNRPYNFEDCVKWARLEFEKKFSYDIQQFLYNFPKDATTSTGEPFWSGPKRAPEPLVFN 718
+++P +F CV+WARL +E ++ I+Q L+NFP D TS+G+PFWSGPKR P+PLVF+
Sbjct: 648 IDDKPKSFAHCVEWARLYWEDQYVNQIKQLLFNFPPDQITSSGQPFWSGPKRCPDPLVFD 707
Query: 719 IENPDHFHFIVASANLRAFNYGLKGDDGKPDINYYQSVLSKLIVPEFIPKADIKIQTNDD 778
+ +P H FI A+ANLRA YG++ + I ++ K+ VPEF P++ +KI+TN+
Sbjct: 708 VNDPMHLDFIYAAANLRAEVYGIEQVRNRETI---AELVQKVKVPEFKPRSGVKIETNEA 764
Query: 779 EPDPNANN----QLGGDVLENLAASLPDASTLAGFQLIPVEFEKDDDTNHHIEFITAASN 834
+ANN +L D ++ + + L + + ++ P+EFEKDDD+N H++FI A SN
Sbjct: 765 AAAASANNFDDGELDQDRVDKIISELLKNADKSS-KITPLEFEKDDDSNLHMDFIVACSN 823
Query: 835 NRALNYSIEPADRQKTKFIAGRIIPAIATTTALVTGLVNLELYKVVAGKTDIEQYKNGFV 894
RA NY I PADR K+K IAG+IIPAIATTT++++GL LE+ K++ G D+ ++KNGF
Sbjct: 824 LRAANYKIPPADRHKSKLIAGKIIPAIATTTSVLSGLAVLEVIKLIVGHRDLVKFKNGFA 883
Query: 895 NLALPFFGFSEPIASQKGKYNDKTFDKIWDRFDIQGDITLRELIDHFNKEEGLEITMVSY 954
NLALPF FSEP+ + K Y K + +WDRF++ G+++L+E +++F + E L+ITM+S
Sbjct: 884 NLALPFMAFSEPLPAAKNTYYGKEW-TLWDRFEVTGELSLQEFLNYFEENEKLKITMLSQ 942
Query: 955 DVSLLYASFFPPKKLKDRMDLPITEVVKLVTKKEILSHVKTMILEFCCEDKEGEDVEVPY 1014
VS+LY+ F P K +R+ LP++EVV+ V+K+ + H ++++ E CC D +GEDVEVPY
Sbjct: 943 GVSMLYSFFMPKAKCSERLPLPMSEVVRRVSKRRLEPHERSLVFEICCNDVDGEDVEVPY 1002
Query: 1015 V 1015
V
Sbjct: 1003 V 1003
>At5g06460 [O] KOG2012 Ubiquitin activating enzyme UBA1
Length = 1077
Score = 868 bits (2242), Expect = 0.0
Identities = 480/1029 (46%), Positives = 667/1029 (64%), Gaps = 28/1029 (2%)
Query: 3 NIKVDGEEIDESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTL 62
N + +EIDE L+SRQL V G+E M K+ SNVLI G++GLGVEIAKN++LAGVKS+TL
Sbjct: 62 NDNSNNQEIDEDLHSRQLAVYGRETMRKLFASNVLISGMQGLGVEIAKNIILAGVKSVTL 121
Query: 63 YDPSAVALQDLSTQFFLSEQDIGQARDKVSQAKLAELNSYVPVKVLEGLEDVSQLSEFQV 122
+D + V L DLS+ F +E+DIG+ R S KL ELN+ V V L G QLS+FQV
Sbjct: 122 HDENVVELWDLSSNFVFTEEDIGKNRALASVHKLQELNNAVAVSTLTGKLTKEQLSDFQV 181
Query: 123 VVVTDTISLEEKVKLNEYTHSHG--IGFISTETRGLFGNVFVDLGEEFTVIDTTGEEPKT 180
VV D IS E+ ++++Y HSH I FI + RGLFG++F D G FTV+D GEEP +
Sbjct: 182 VVFVD-ISFEKATEIDDYCHSHQPPIAFIKADVRGLFGSLFCDFGPHFTVLDVDGEEPHS 240
Query: 181 GIVSDI--ESDGTVTMLDDNRHGLEDGNYVKFSEVEGLEKLNDGTPYKVEVLGPFAFKIG 238
GI++ + E+ G V+ +DD R EDGN V FSEVEG+ +LNDG P K++ + PF+F +
Sbjct: 241 GIIASVSNENPGFVSCVDDERLEFEDGNLVVFSEVEGMTELNDGKPRKIKNVKPFSFTLE 300
Query: 239 S-VKDLGTYKKGGLFTEVKMPQKLTFKSLRESLATP-EFLYSDFAKFETTAQLHLGFQAL 296
G Y KGG+ T+VK P+ L FK LRE+L P +FL SDF+KF+ LHL FQAL
Sbjct: 301 EDTSSYGQYMKGGIVTQVKQPKVLNFKPLREALKDPGDFLLSDFSKFDRPPLLHLAFQAL 360
Query: 297 HQFQVRHQGELPRPFYEEDSNELVKLVIDLATQQPEVLGSEG--KVDEKLITELANQARG 354
+F + G P EED+ +LV++ +D+ E LG V+ KL+ LA +R
Sbjct: 361 DRFSSQ-AGRFPFAGSEEDAQKLVEIAVDIN----EGLGDARLEDVNSKLLRHLAFGSRA 415
Query: 355 DIPGIVAFFGGLVAQEVLKASSGKFTPIKQYMYFDSIESLPDSEDFPRNADTTKPINSRY 414
+ + A FGG+V QEV+KA SGKF PI Q+ YFDS+ESLP P +A +P NSRY
Sbjct: 416 VLNPMAAMFGGIVGQEVVKACSGKFHPIFQFFYFDSVESLPKE---PLDASEFRPQNSRY 472
Query: 415 DNQISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKS 474
D QISVFG QK++ + +VF+VG+GA+GCE LKN AL+G++ G +GK+ VTD+D IEKS
Sbjct: 473 DAQISVFGSTLQKKLEDARVFVVGAGALGCEFLKNLALMGVSCGTQGKLTVTDDDVIEKS 532
Query: 475 NLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLD 534
NL+RQFLFR ++G+ KS VAA A + +N L I+ ++VG ETEN+F+D+FW L
Sbjct: 533 NLSRQFLFRDWNIGQAKSTVAATAAAGINSRLN--IDALQNRVGPETENVFDDSFWENLT 590
Query: 535 FVTNALDNVDARTYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEKSI 594
V NALDNV AR YVD RCV+++KPLLESGTLG K NTQ+VIP+LTE+Y +SRDPPEK
Sbjct: 591 VVVNALDNVTARLYVDSRCVYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQA 650
Query: 595 PLCTLRSFPNKIDHTIAWAKSLFQGYFSDAAENVNLYLTQPNFVEQTLKQAPD--AKGIL 652
P+CT+ SFP+ IDH + WA+S F+G VN YL+ P + ++ A D A+ L
Sbjct: 651 PMCTVHSFPHNIDHCLTWARSEFEGLLEKTPAEVNAYLSDPVEYMKAMRTAGDAQARDTL 710
Query: 653 ESISDCLNNRPYN-FEDCVKWARLEFEKKFSYDIQQFLYNFPKDATTSTGEPFWSGPKRA 711
+ +CL N F+DC+ WARL FE F+ ++Q Y FP+DA TSTG PFWS PKR
Sbjct: 711 GRVVECLEKEKCNSFQDCITWARLRFEDYFANRVKQLCYTFPEDAATSTGAPFWSAPKRF 770
Query: 712 PEPLVFNIENPDHFHFIVASANLRAFNYGLKGDDGKPDINYYQSVLSKLIVPEFIPKADI 771
P PL F+ + H +F++A++ LRA +G+ + + ++IVP+F PK D
Sbjct: 771 PRPLQFSSTDLSHINFVMAASILRAETFGIPTPEWAKTRAGLAEAVERVIVPDFEPKKDA 830
Query: 772 KIQTNDDEPDPNANNQLGGDVLENLAASLPDA--STLAGFQLIPVEFEKDDDTNHHIEFI 829
I T++ + + V++ L A L S F++ ++FEKDDDTN+H++ I
Sbjct: 831 TIVTDEKATTLSTASVDDAAVIDELNAKLVRCRMSLQPEFRMKAIQFEKDDDTNYHMDMI 890
Query: 830 TAASNNRALNYSIEPADRQKTKFIAGRIIPAIATTTALVTGLVNLELYKVVAGKTDIEQY 889
+N RA NYS+ D+ K KFIAGRIIPAIAT+TA+ TG V LE+YKV+ G +E Y
Sbjct: 891 AGLANMRARNYSVPEVDKLKAKFIAGRIIPAIATSTAMATGFVCLEMYKVLDGSHKVEDY 950
Query: 890 KNGFVNLALPFFGFSEPIASQKGKYNDKTFDKIWDRFDIQGDITLRELIDHFNKEEGLEI 949
+N F NLALP F +EP+ + K+ D+++ +WDR+ ++G+ TLREL+D + KE+GL
Sbjct: 951 RNTFANLALPLFSMAEPVPPKVVKHQDQSW-TVWDRWVMRGNPTLRELLD-WLKEKGLNA 1008
Query: 950 TMVSYDVSLLYASFFPPKKLKDRMDLPITEVVKLVTKKEILSHVKTMILEFCCEDKEGED 1009
+S SLLY S F + K+RM+ + ++ + V E+ ++ + + + CED D
Sbjct: 1009 YSISCGSSLLYNSMF--SRHKERMNRRVVDLARDVAGVELPAYRRHVDVVVACEDDNDAD 1066
Query: 1010 VEVPYVTVH 1018
V++P V+V+
Sbjct: 1067 VDIPLVSVY 1075
>At2g30110 [O] KOG2012 Ubiquitin activating enzyme UBA1
Length = 1080
Score = 865 bits (2235), Expect = 0.0
Identities = 472/1021 (46%), Positives = 661/1021 (64%), Gaps = 24/1021 (2%)
Query: 9 EEIDESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAV 68
+EIDE L+SRQL V G+E M ++ SNVLI G+ GLG EIAKN++LAGVKS+TL+D V
Sbjct: 71 QEIDEDLHSRQLAVYGRETMRRLFASNVLISGMHGLGAEIAKNLILAGVKSVTLHDERVV 130
Query: 69 ALQDLSTQFFLSEQDIGQARDKVSQAKLAELNSYVPVKVLEGLEDVSQLSEFQVVVVTDT 128
L DLS+ F SE D+G+ R S KL +LN+ V V L + LS FQVVV +D
Sbjct: 131 ELWDLSSNFVFSEDDVGKNRADASVQKLQDLNNAVVVSSLTKSLNKEDLSGFQVVVFSD- 189
Query: 129 ISLEEKVKLNEYTHSHG--IGFISTETRGLFGNVFVDLGEEFTVIDTTGEEPKTGIVSDI 186
IS+E ++ ++Y HSH I F+ + RGLFG+VF D G EF V+D GEEP TGI++ I
Sbjct: 190 ISMERAIEFDDYCHSHQPPIAFVKADVRGLFGSVFCDFGPEFAVLDVDGEEPHTGIIASI 249
Query: 187 --ESDGTVTMLDDNRHGLEDGNYVKFSEVEGLEKLNDGTPYKVEVLGPFAFKIGS-VKDL 243
E+ ++ +DD R EDG+ V FSEVEG+ +LNDG P K++ P++F + +
Sbjct: 250 SNENQAFISCVDDERLEFEDGDLVVFSEVEGMTELNDGKPRKIKSTRPYSFTLDEDTTNY 309
Query: 244 GTYKKGGLFTEVKMPQKLTFKSLRESLATP-EFLYSDFAKFETTAQLHLGFQALHQFQVR 302
GTY KGG+ T+VK P+ L FK LRE+L P +FL+SDF+KF+ LHL FQAL F+
Sbjct: 310 GTYVKGGIVTQVKQPKLLNFKPLREALKDPGDFLFSDFSKFDRPPLLHLAFQALDHFKAE 369
Query: 303 HQGELPRPFYEEDSNELVKLVIDLATQQPEVLGSEGKVDEKLITELANQARGDIPGIVAF 362
G P EED+ +L+ + + T Q ++ VD+KL+ + A+ + + A
Sbjct: 370 -AGRFPVAGSEEDAQKLISIATAINTGQGDL--KVENVDQKLLRHFSFGAKAVLNPMAAM 426
Query: 363 FGGLVAQEVLKASSGKFTPIKQYMYFDSIESLPDSEDFPRNADTTKPINSRYDNQISVFG 422
FGG+V QEV+KA SGKF P+ Q+ YFDS+ESLP P ++ P NSRYD QISVFG
Sbjct: 427 FGGIVGQEVVKACSGKFHPLFQFFYFDSVESLPSE---PVDSSDFAPRNSRYDAQISVFG 483
Query: 423 LEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLF 482
+FQK++ + KVF VGSGA+GCE LKN AL+G++ G +GK+ VTD+D IEKSNL+RQFLF
Sbjct: 484 AKFQKKLEDAKVFTVGSGALGCEFLKNLALMGVSCGSQGKLTVTDDDIIEKSNLSRQFLF 543
Query: 483 RPKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNALDN 542
R ++G+ KS VAA A + +NP + IE ++VGAETEN+F+DAFW L V NALDN
Sbjct: 544 RDWNIGQAKSTVAASAAAVINP--RFNIEALQNRVGAETENVFDDAFWENLTVVVNALDN 601
Query: 543 VDARTYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEKSIPLCTLRSF 602
V+AR YVD RC++++KPLLESGTLGTK NTQ VIP+LTE+Y +SRDPPEK P+CT+ SF
Sbjct: 602 VNARLYVDSRCLYFQKPLLESGTLGTKCNTQSVIPHLTENYGASRDPPEKQAPMCTVHSF 661
Query: 603 PNKIDHTIAWAKSLFQGYFSDAAENVNLYLTQPNFVEQTLKQAPD--AKGILESISDCL- 659
P+ IDH + WA+S F+G VN YL+ P ++ A D A+ LE I +CL
Sbjct: 662 PHNIDHCLTWARSEFEGLLEKTPAEVNAYLSSPVEYTNSMMSAGDAQARDTLERIVECLE 721
Query: 660 NNRPYNFEDCVKWARLEFEKKFSYDIQQFLYNFPKDATTSTGEPFWSGPKRAPEPLVFNI 719
+ F+DC+ WARL FE F ++Q +Y FP+DA TSTG PFWS PKR P PL ++
Sbjct: 722 KEKCETFQDCLTWARLRFEDYFVNRVKQLIYTFPEDAATSTGAPFWSAPKRFPRPLQYSS 781
Query: 720 ENPDHFHFIVASANLRAFNYGLKGDDGKPDINYYQSVLSKLIVPEFIPKADIKIQTNDDE 779
+P +FI A+A LRA +G+ + + + ++IVP+F P+ D KI T++
Sbjct: 782 SDPSLLNFITATAILRAETFGIPIPEWTKNPKEAAEAVDRVIVPDFEPRQDAKIVTDEKA 841
Query: 780 PDPNANNQLGGDVLENLAASLPDA--STLAGFQLIPVEFEKDDDTNHHIEFITAASNNRA 837
+ V+++L A + + F++ P++FEKDDDTN+H++ I +N RA
Sbjct: 842 TTLTTASVDDAAVIDDLIAKIDQCRHNLSPDFRMKPIQFEKDDDTNYHMDVIAGLANMRA 901
Query: 838 LNYSIEPADRQKTKFIAGRIIPAIATTTALVTGLVNLELYKVVAGKTDIEQYKNGFVNLA 897
NYSI D+ K KFIAGRIIPAIAT+TA+ TGLV LELYKV+ G +E Y+N F NLA
Sbjct: 902 RNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEAYRNTFANLA 961
Query: 898 LPFFGFSEPIASQKGKYNDKTFDKIWDRFDIQGDITLRELIDHFNKEEGLEITMVSYDVS 957
LP F +EP+ + K+ D + +WDR+ ++G+ TLRE++ + +++GL +S
Sbjct: 962 LPLFSMAEPLPPKVVKHRDMAW-TVWDRWVLKGNPTLREVL-QWLEDKGLSAYSISCGSC 1019
Query: 958 LLYASFFPPKKLKDRMDLPITEVVKLVTKKEILSHVKTMILEFCCEDKEGEDVEVPYVTV 1017
LL+ S F + K+RMD + ++ + V K E+ + + + CED++ DV++P V++
Sbjct: 1020 LLFNSMF--TRHKERMDKKVVDLARDVAKVELPPYRNHLDVVVACEDEDDNDVDIPLVSI 1077
Query: 1018 H 1018
+
Sbjct: 1078 Y 1078
>CE05449 [O] KOG2012 Ubiquitin activating enzyme UBA1
Length = 1113
Score = 761 bits (1964), Expect = 0.0
Identities = 438/1029 (42%), Positives = 642/1029 (61%), Gaps = 42/1029 (4%)
Query: 9 EEIDESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAV 68
E +D++LYSRQ+Y LG+ AM+ ++ ++VLI GL +GVEIAKN++L GV+ +T++D
Sbjct: 101 ELLDKNLYSRQIYTLGESAMVNLRTASVLISGLGSVGVEIAKNLILGGVRHVTIHDTKLA 160
Query: 69 ALQDLSTQFFLSEQDIGQARDKVSQAKLAELNSYVPVKVLEGLEDVSQLSEFQVVVVTDT 128
DLS Q++L + D+G R +LAELN V V+V + F +VV+TD
Sbjct: 161 KWSDLSAQYYLRDADVGHNRATSCYERLAELNDSVNVQVSTDELTEEFVKTFDLVVLTDA 220
Query: 129 ISLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDTTGEEPKTGIVSDIE- 187
++ ++ +T +H + T+ RG+F +F D G+ F + D TGE+ + + I+
Sbjct: 221 ARTAQR-QIAAWTRAHNRRILITDARGVFSYIFNDFGDNFRIDDATGEQVREFFIEHIDK 279
Query: 188 SDGTVTMLDDNRHGLEDGNYVKFSEVEGLEKLNDGTPYKVEVLGPFAFKIGSVK-DLGTY 246
+ G VT L++ HGLEDG++V FSEV+GL ++N P K+ V F IG Y
Sbjct: 280 TTGEVTTLENLFHGLEDGDHVTFSEVKGLTEINGCEPLKITVKNASKFNIGDFAVSFSDY 339
Query: 247 KKGGLFTEVKMPQKLTFKSLRESLATPEFLYSDFAKFETTAQLHLGFQALHQFQVRHQGE 306
K+GG +VK+P ++ +SL PEF D+AKFE +QLH + AL+ F+ ++ G
Sbjct: 340 KEGGRCRQVKVPTSVSHVPFEKSLVEPEFGIWDYAKFEYPSQLHALWTALYAFEEKY-GR 398
Query: 307 LPRPFYEEDSNELVKLVIDLATQQPEVLGSEGKVDEKLITELANQARGDIPGIVAFFGGL 366
P P +D+ L+K +I T++ + EKLI + A G++ + + GG+
Sbjct: 399 SPAPRSTQDA-ALLKELIPSGTEE---------IPEKLIELFSFSASGNLVTVSSVVGGI 448
Query: 367 VAQEVLKASSGKFTPIKQYMYFDSIESLPD---SEDFPRNADTT-KPINSRYDNQISVFG 422
AQE +K + TP+KQ+++ D +E LP S D + ++T +P SRYD Q +VFG
Sbjct: 449 AAQEAMKGVTHHMTPLKQWLHLDHVEVLPGDWTSFDNSKLSETDCQPRQSRYDGQAAVFG 508
Query: 423 LEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLF 482
+Q+ + + F+VG+GAIGCE+LKN +++G+A G G I +TD D IE SNLNRQFLF
Sbjct: 509 WPYQECLFRQRWFVVGAGAIGCELLKNLSMMGVACGEGGLIKITDMDQIEISNLNRQFLF 568
Query: 483 RPKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNALDN 542
R +DVG KSE AA AV+A N D++ IE ++VG ETE+IFND F+ +L+ V NALDN
Sbjct: 569 RRRDVGGKKSECAARAVTAFNSDVR--IEALAERVGLETEHIFNDEFFGELNGVANALDN 626
Query: 543 VDARTYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEKSIPLCTLRSF 602
VDAR Y+DRRCV+Y+ PLLESGT+GTKGNTQVV P LTESYSSS DPPEK IP+CTL++F
Sbjct: 627 VDARRYMDRRCVYYRLPLLESGTMGTKGNTQVVYPYLTESYSSSVDPPEKEIPVCTLKNF 686
Query: 603 PNKIDHTIAWAKSLFQGYFSDAAENVNLYLTQPNFVEQTLKQAPDAK--GILESISDCL- 659
PN+I HTI WA+ F+ +F+ E N +L+ + + + + IL+ + D L
Sbjct: 687 PNEIQHTIQWAREQFETFFAQPGEMANKFLSDERGFNEHVDKLISGQQIDILQKVKDALI 746
Query: 660 NNRPYNFEDCVKWARLEFEKKFSYDIQQFLYNFPKDATTSTGEPFWSGPKRAPEPLVFNI 719
+ RP + EDC++WAR +F++ + +I Q L++FP D T +G FWSG KR P L F+
Sbjct: 747 DARPSSAEDCIRWARNQFQELYHNNIAQMLHSFPPDQLTDSGAKFWSGAKRCPHVLNFDP 806
Query: 720 ENPDHFHFIVASANLRAFNYGLKGDDGKPDINYYQSVLSKLIV-PE-FIPKADIKIQTND 777
+HF+F+ A++ L A YG+ +P ++ + + L V PE F PK+ +KI D
Sbjct: 807 SKEEHFNFVFAASILIAELYGV-----QPILDREEVIRVALSVNPEPFEPKSGVKIAVTD 861
Query: 778 ----DEPDPNANNQLGGD--VLENLAASLPDASTLAGFQLIPVEFEKDDDTNHHIEFITA 831
++ + A++ + D +E L L + + +L V+FEKDDD+NHH+EFITA
Sbjct: 862 AEAKEQNERGASSMIVDDDAAIEALKLKLATLNVKSTSKLNCVDFEKDDDSNHHMEFITA 921
Query: 832 ASNNRALNYSIEPADRQKTKFIAGRIIPAIATTTALVTGLVNLELYKVVAG----KTDIE 887
ASN RA NY I PADR +TK IAG+IIPAIATTTA V GLV +ELYKVV KT +E
Sbjct: 922 ASNLRAENYDILPADRMRTKQIAGKIIPAIATTTAAVAGLVCIELYKVVDANGIPKTPME 981
Query: 888 QYKNGFVNLALPFFGFSEPIASQKGKYNDKTFDKIWDRFDIQGDITLRELIDHF-NKEEG 946
++KN F+NL++PFF +EPI + K Y D+ F +WDR D+QG +TL+E ID+ N+ G
Sbjct: 982 RFKNTFLNLSMPFFSSAEPIGAPKKTYMDREF-TLWDRIDVQGPLTLQEFIDNVQNQTGG 1040
Query: 947 LEITMVSYDVSLLYASFFPPKKLKDRMDLPITEVVKLVTKKEILSHVKTMILEFCCEDKE 1006
E++M+S LL++ F K ++R+ + V + + KK + V ++LE D +
Sbjct: 1041 CEVSMLSAGACLLFSFFMNAGKKQERLKTEVKAVYEELLKKSLHPSVHALVLEPMMSDPD 1100
Query: 1007 GEDVEVPYV 1015
GEDVEVPY+
Sbjct: 1101 GEDVEVPYI 1109
>SPBC211.09 [O] KOG2012 Ubiquitin activating enzyme UBA1
Length = 644
Score = 756 bits (1952), Expect = 0.0
Identities = 381/639 (59%), Positives = 484/639 (75%), Gaps = 8/639 (1%)
Query: 5 KVDGEEIDESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYD 64
+ D IDE LYSRQLYVLG EAM +M SNVLIIG KGLGVEIAKNV LAGVKS+TLYD
Sbjct: 9 QTDQNTIDEGLYSRQLYVLGHEAMKQMSQSNVLIIGCKGLGVEIAKNVCLAGVKSVTLYD 68
Query: 65 PSAVALQDLSTQFFLSEQDIGQARDKVSQAKLAELNSYVPVKVLEGLEDVSQLSEFQVVV 124
P ++DLS+Q+FL+E DIG R KV+ +KLAELN YVPV V++ L L F+ VV
Sbjct: 69 PQPTRIEDLSSQYFLTEDDIGVPRAKVTVSKLAELNQYVPVSVVDELS-TEYLKNFKCVV 127
Query: 125 VTDTISLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDTTGEEPKTGIVS 184
VT+T SL +++++N++TH + I +I+ ++RGLFG++F D GE F DT G EP TG+++
Sbjct: 128 VTET-SLTKQLEINDFTHKNHIAYIAADSRGLFGSIFCDFGENFICTDTDGNEPLTGMIA 186
Query: 185 DIESDGTVTMLDDNRHGLEDGNYVKFSEVEGLEKLNDGTPYKVEVLGPFAFKIGSVKDLG 244
I DG VTML++ RHGLE+G++VKF+EV+G+ LNDGTP KVEV GP+ F IGSVKDLG
Sbjct: 187 SITDDGVVTMLEETRHGLENGDFVKFTEVKGMPGLNDGTPRKVEVKGPYTFSIGSVKDLG 246
Query: 245 TYKKGGLFTEVKMPQKLTFKSLRESLATPEFLYSDFAKFETTAQLHLGFQALHQFQVRHQ 304
+ G+FT+VK+P K++FKSLRESL PE++Y DF K Q H+ FQAL F H+
Sbjct: 247 SAGYNGVFTQVKVPTKISFKSLRESLKDPEYVYPDFGKMMRPPQYHIAFQALSAFADAHE 306
Query: 305 GELPRPFYEEDSNELVKLVIDLATQQPEVLGSEGKVDEKLITELANQARGDIPGIVAFFG 364
G LPRP + D+ E + +A+ L + ++DEKLI E++ QARGD+ + AF G
Sbjct: 307 GSLPRPRNDIDAAEFFEFCKKIAS----TLQFDVELDEKLIKEISYQARGDLVAMSAFLG 362
Query: 365 GLVAQEVLKASSGKFTPIKQYMYFDSIESLPDSEDFPRNADTTKPINSRYDNQISVFGLE 424
G VAQEVLKA++ KF P+KQY YFDS+ESLP S + +T KP RYD QI+VFG E
Sbjct: 363 GAVAQEVLKATTSKFYPLKQYFYFDSLESLPSSVTI--SEETCKPRGCRYDGQIAVFGSE 420
Query: 425 FQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRP 484
FQ++IA+L FLVG+GAIGCEMLKNWA++G+A+G G I VTD DSIEKSNLNRQFLFRP
Sbjct: 421 FQEKIASLSTFLVGAGAIGCEMLKNWAMMGVATGESGHISVTDMDSIEKSNLNRQFLFRP 480
Query: 485 KDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNALDNVD 544
+DVG+ KSE A+ AVS MNP L GKI ++VG E+E IF D F+ +L VTNALDNV+
Sbjct: 481 RDVGKLKSECASTAVSIMNPSLTGKITSYQERVGPESEGIFGDEFFEKLSLVTNALDNVE 540
Query: 545 ARTYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEKSIPLCTLRSFPN 604
AR YVDRRCVF++KPLLESGTLGTKGNTQVV+P+LTESY SS+DPPEKS P+CTL++FPN
Sbjct: 541 ARMYVDRRCVFFEKPLLESGTLGTKGNTQVVVPHLTESYGSSQDPPEKSFPICTLKNFPN 600
Query: 605 KIDHTIAWAKSLFQGYFSDAAENVNLYLTQPNFVEQTLK 643
+I+HTIAWA+ LF+G F +NVN+YL+ PNF+E +LK
Sbjct: 601 RIEHTIAWARDLFEGLFKQPIDNVNMYLSSPNFLETSLK 639
>Hs21361718 [O] KOG2012 Ubiquitin activating enzyme UBA1
Length = 1052
Score = 690 bits (1781), Expect = 0.0
Identities = 423/1030 (41%), Positives = 608/1030 (58%), Gaps = 48/1030 (4%)
Query: 10 EIDESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVA 69
EID++LYSRQ YVLG AM KM S+V + G+ GLG+EIAKN+VLAG+K++T++D
Sbjct: 38 EIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQ 97
Query: 70 LQDLSTQFFLSEQDIGQARDKVSQA--KLAELNSYVPVKV----LEGLEDVSQLSEFQVV 123
DL T FFLSE D+ R++ +AELN YV V D+S L ++Q V
Sbjct: 98 AWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCV 157
Query: 124 VVTDTISLEEKVKLNEYTHSH--GIGFISTETRGLFGNVFVDLGEEFTVIDTTGEEPKTG 181
V+T+ + L + K+N++ S I FIS + G++ +F D G+EF V+DTTGEEPK
Sbjct: 158 VLTE-MKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTTGEEPKEI 216
Query: 182 IVSDIE--SDGTVTMLDDNRHGLEDGNYVKFSEVEGLEKLNDGTPYKVEVLGPFAFKIGS 239
+S+I + G VT L+++ H LE G ++ F E+ G+ LN G+ ++ V+ PF+F IG
Sbjct: 217 FISNITQANPGIVTCLENHPHKLETGQFLTFREINGMTGLN-GSIQQITVISPFSFSIGD 275
Query: 240 VKDLGTYKKGGLFTEVKMPQKLTFKSLRESLATPEFLYSDFAKFETTAQLHLGFQALHQF 299
+L Y GG+ +VK P+ + F+SL L P+ L DF+ E ++H AL QF
Sbjct: 276 TTELEPYLHGGIAVQVKTPKTVFFESLERQLKHPKCLIVDFSNPEAPLEIHTAMLALDQF 335
Query: 300 QVRHQGELPRPFYEEDSNELVKLVIDLATQQPEVLGSEGKVDEKLITELANQARGDIPGI 359
Q ++ + P ++DS EL+KL AT E L + V+ ++ L+ A+G + +
Sbjct: 336 QEKYSRK-PNVGCQQDSEELLKL----ATSISETLEEKPDVNADIVHWLSWTAQGFLSPL 390
Query: 360 VAFFGGLVAQEVLKASSGKFTPIKQYMYF---DSIESL--PDSEDFPRNADTTKPINSRY 414
A GG+ +QEVLKA +GKF+P+ Q++Y D +ESL P+ E+F P RY
Sbjct: 391 AAAVGGVASQEVLKAVTGKFSPLCQWLYLEAADIVESLGKPECEEF-------LPRGDRY 443
Query: 415 DNQISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPE-GKIIVTDNDSIEK 473
D + G +++ NL +FLVG GAIGCEMLKN+ALLG+ + E G I VTD D IEK
Sbjct: 444 DALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTSKEKGMITVTDPDLIEK 503
Query: 474 SNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQL 533
SNLNRQFLFRP + + KS AADA +N +K I+ ++KV TE I+ND F+ +
Sbjct: 504 SNLNRQFLFRPHHIQKPKSYTAADATLKINSQIK--IDAHLNKVCPTTETIYNDEFYTKQ 561
Query: 534 DFVTNALDNVDARTYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEKS 593
D + ALDNV+AR YVD RC+ +PLL+SGT+GTKG+T+V++P+LTESY+S RDPPE+
Sbjct: 562 DVIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEEE 621
Query: 594 IPLCTLRSFPNKIDHTIAWAKSLFQGYFSDAAENVNLYLTQPNFVEQTLKQAPDAKGI-- 651
IP CTL+SFP I+HTI WA+ F+ FS N + + E+ L++ +
Sbjct: 622 IPFCTLKSFPAAIEHTIQWARDKFESSFSHKPSLFNKFWQTYSSAEEVLQKIQSGHSLEG 681
Query: 652 LESISDCLNNRPYNFEDCVKWARLEFEKKFSYDIQQFLYNFPKDATTSTGEPFWSGPKRA 711
+ L+ RP N+ CV+ ARL+FEK F++ Q L+ FP D G FW PKR
Sbjct: 682 CFQVIKLLSRRPRNWSQCVELARLKFEKYFNHKALQLLHCFPLDIRLKDGSLFWQSPKRP 741
Query: 712 PEPLVFNIENPDHFHFIVASANLRAFNYGLKGDDGKPDINYYQSVLSKLIVPEFIPKADI 771
P P+ F++ P H F+ +A L A Y + + + ++LS++ + EF P +
Sbjct: 742 PSPIKFDLNEPLHLSFLQNAAKLYATVYCIPFAEEDLSADALLNILSEVKIQEFKPSNKV 801
Query: 772 KIQTNDD--EPD--PNANNQLGGDVLENLAASLPDASTLAGFQLIPVEFEKDDDTNHHIE 827
+QT++ +PD P ++ + + A L + +T + Q+ + FEKDDD N HI+
Sbjct: 802 -VQTDETARKPDHVPISSEDERNAIFQLEKAILSNEATKSDLQMAVLSFEKDDDHNGHID 860
Query: 828 FITAASNNRALNYSIEPADRQKTKFIAGRIIPAIATTTALVTGLVNLELYKVVAGKTDIE 887
FITAASN RA YSIEPADR KTK IAG+IIPAIATTTA V+GLV LE+ KV G E
Sbjct: 861 FITAASNLRAKMYSIEPADRFKTKRIAGKIIPAIATTTATVSGLVALEMIKVTGG-YPFE 919
Query: 888 QYKNGFVNLALPFFGFSEPIASQKGKYNDKTFDKIWDRFDIQG--DITLRELIDHFNKEE 945
YKN F+NLA+P F+E +K K + IWDR+ + G D TL + I+ ++
Sbjct: 920 VYKNCFLNLAIPIVVFTETTEVRKTKIRNGISFTIWDRWTVHGKEDFTLLDFINAVKEKY 979
Query: 946 GLEITMVSYDVSLLYASFFPPKKLKDRMDLPITEVVKLVTKKEILSHVKTMILEFCCEDK 1005
G+E TMV V +LY P R+ L + ++VK T+K+ + + + F +
Sbjct: 980 GIEPTMVVQGVKMLYVPVMPGH--AKRLKLTMHKLVKPTTEKKYVD----LTVSFAPDID 1033
Query: 1006 EGEDVEVPYV 1015
ED+ P V
Sbjct: 1034 GDEDLPGPPV 1043
>Hs4507767 [O] KOG2012 Ubiquitin activating enzyme UBA1
Length = 1011
Score = 632 bits (1631), Expect = 0.0
Identities = 388/1018 (38%), Positives = 579/1018 (56%), Gaps = 29/1018 (2%)
Query: 11 IDESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVAL 70
+DE LYSRQLYVLG AM ++Q + VL+ GL+GLG E+AKN+VL GV SLTL+DP
Sbjct: 10 LDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCW 69
Query: 71 QDLSTQFFLSEQDIGQARDKVSQAKLAELNSYVPVKVLEGLEDVSQLSEFQVVVVTDTIS 130
DL+ QF LSEQD+ ++R + SQ LA+LN V V V G L +FQVVV+T
Sbjct: 70 SDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQVVVLT-AAK 128
Query: 131 LEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDTTGEEPKTGIVSDIE--S 188
LEE++K+ H HG+ F++ +TRGL G +F D GE+FTV D T EP T + I S
Sbjct: 129 LEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQHISQGS 188
Query: 189 DGTVTMLDD-NRHGLEDGNYVKFSEVEGLEKLNDGTPYKVEVLGPFAFKIGSVKDLGTYK 247
G +T+ N H DG+ V FS +EG+ +LND P + V + +IG Y
Sbjct: 189 PGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYL 248
Query: 248 KGGLFTEVKMPQKLTFKSLRESLATPEFLYSDFAKFETTAQLHLGFQALHQFQVRHQGEL 307
+GG TEVK P+ + KSL +L P + + LH F ALH+FQ H G
Sbjct: 249 RGGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKFQHLH-GRP 307
Query: 308 PRPFYEEDSNELVKLVIDLAT-QQPEVLGSEGKVDEKLITELANQARGDIPGIVAFFGGL 366
P+P+ D+ +V L DL ++ E E +DE L+ +A + + +VA +
Sbjct: 308 PQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSARCLEPMVACWVSS 367
Query: 367 VAQEVLKASSGKFTPIKQYMYFDSIESLPDSEDFPRNADTTKPINSRYDNQISVFGLEFQ 426
+ + KF P+ Q++YFD+++ LP+ + + + SRYD QI+VFG FQ
Sbjct: 368 CPGSA-EGNLQKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIAVFGAGFQ 426
Query: 427 KRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKD 486
+++ LVG+GAIGCE+LK +AL+GL +G G + V D D IE+SNL+RQFLFR +D
Sbjct: 427 EKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQD 486
Query: 487 VGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNALDNVDAR 546
VGR K+EVAA A +NPDL ++ P + TE+I+ D F++++D V ALD+ AR
Sbjct: 487 VGRPKAEVAAAAARGLNPDL--QVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQAR 544
Query: 547 TYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESY---SSSRDPPEKSIPLCTLRSFP 603
YV RC Y KPLLE+GT GT G+ V +P++TE+Y +S+ + P+CT+R FP
Sbjct: 545 RYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFP 604
Query: 604 NKIDHTIAWAKSLFQGYFSDAAENVNLYLTQPNFVEQTLKQAPDAKGILESISDCLNNRP 663
+ +HT+ WA+ F+ F +AE +N + Q P +L+ + L RP
Sbjct: 605 STAEHTLQWARHEFEELFRLSAETINHH--QQAHTSLADMDEPQTLTLLKPVLGVLRVRP 662
Query: 664 YNFEDCVKWARLEFEKKFSYDIQQFLYNFPKDATTSTGEPFWSGPKRAPEPLVFNIENPD 723
N++DCV WA ++ F Y I+Q L +FP + G PFWSGPK+ P+PL F+
Sbjct: 663 QNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTNQDT 722
Query: 724 HFHFIVASANLRAFNYGLKGDDGKPDINYYQSVLSKLIVPEFIPKADIKIQTNDDEPDPN 783
H +++A+ANL A +GL G D + +L L P+ P+ I ++ E +
Sbjct: 723 HLLYVLAAANLYAQMHGLPGSQ---DWTALRELLKLLPQPD--PQQMAPIFASNLEL-AS 776
Query: 784 ANNQLGGDVLENLAASLPDASTLAGFQLIPVEFEKDDDTNHHIEFITAASNNRALNYSIE 843
A+ + G + + L +L S G L P+ FEKDDD+N H++F+ AA++ R NY I
Sbjct: 777 ASAEFGPEQQKELNKALEVWS--VGPPLKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIP 834
Query: 844 PADRQKTKFIAGRIIPAIATTTALVTGLVNLELYKVVAGKTDIEQYKNGFVNLALPFFGF 903
P +R ++K I G+IIPAIATTTA V GL+ LELYKVV+G +++ +++LA +
Sbjct: 835 PVNRAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIR 894
Query: 904 SEPIASQKGKYNDKTFDKIWDRFDI---QGDITLRELIDHFNKEEGLEITMVSYDVSLLY 960
P A ++ + WDR + Q + TL L+ H ++ GL + ++ + +LLY
Sbjct: 895 YMPFAPAIQTFHHLKWTS-WDRLKVPAGQPERTLESLLAHLQEQHGLRVRILLHGSALLY 953
Query: 961 ASFFPPKKLKDRMDLPITEVVKLVTKKEILSHVKTMILEFCCEDKEGEDVEVPYVTVH 1018
A+ + P+K + L +TE+V+ +T + + ++LE C EG+D + + +H
Sbjct: 954 AAGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSC---EGDDEDTAFPPLH 1008
>ECU03g0930 [O] KOG2012 Ubiquitin activating enzyme UBA1
Length = 991
Score = 602 bits (1552), Expect = e-172
Identities = 380/1047 (36%), Positives = 558/1047 (53%), Gaps = 120/1047 (11%)
Query: 10 EIDESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVA 69
+IDESLYSRQLYV+GKEAM KM S VL++GL GLG E+ KNV LAG+ + L+D AV+
Sbjct: 8 DIDESLYSRQLYVVGKEAMKKMMGSKVLVMGLDGLGQEVVKNVCLAGISKVALFDDRAVS 67
Query: 70 LQDLSTQFFLSEQDIGQARDKVSQAKLAELNSYVPVKVLEGLEDVSQLSEFQVVVVTDTI 129
+DL + F+L ++DIG+ RD + +N YV V V+ DV+ + +VV +
Sbjct: 68 EEDLCSGFYLRKEDIGKPRDASVVGRFRSMNEYVDVDVVS---DVNSFEGYDIVVACNE- 123
Query: 130 SLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDTTGEEPKTGIVSDIESD 189
S E+++LNE G FI + RGLF VF D G EF +D TGE P +G+++DI D
Sbjct: 124 SYGEQIRLNEMARKDGCMFIGCQVRGLFSQVFCDFGAEFVCVDRTGEIPASGMINDISED 183
Query: 190 GTVTMLDDNRHGLEDGNYVKFSEVEGLEKLNDGTPYKVEVLGPFAFKIGSVKDLGTYKK- 248
G +T++D RH LED + +K ++ + E G ++V+ + P + S+ + +++
Sbjct: 184 GVMTVVDGQRHNLEDYDIIKITQCDEYE----GKYFRVKAVSPTQVMLQSIDGVRMFEEE 239
Query: 249 ------------GGLFTEVKMPQKLTFKSLRESLATPEFLYSDFAKFETTAQLHLGFQAL 296
GG F + K P ++FK L ++ P L + E + +H F AL
Sbjct: 240 MEFKAEKFKPVYGGDFEQQKKPIMISFKPLGRTIDEPGILGFNHEVEERSLVIHKCFVAL 299
Query: 297 HQFQVRHQGELPRPFYEEDSNELVKLVIDLATQQPEVLGSEGKVDEKLITELANQARGDI 356
++ + EL + + K + E LI Q G +
Sbjct: 300 GEYMEQSGQELSGEGFLSFFVKKYKSHFEF---------------EALIRSFGKQCGGML 344
Query: 357 PGIVAFFGGLVAQEVLKASSGKFTPIKQYMYFDSIESLP-DSEDFPRNADTTKPINSRYD 415
+ + GG VAQEVLK KFTP+ Q+ YFD+++ +P D ED R+ RY
Sbjct: 345 MPMCSVIGGFVAQEVLKGVGSKFTPLHQFFYFDAVDVIPNDPEDDGRDY-------GRYG 397
Query: 416 NQISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSN 475
+ G +R+ L VF+VG+GAIGCE LKN + G+ G G+I VTD D+IE+SN
Sbjct: 398 PMVRCLGKRCVERLFGLHVFMVGAGAIGCEHLKNMVMCGI--GSNGRISVTDMDAIEQSN 455
Query: 476 LNRQFLFRPKDVGRNKSEVAADAVSAMNPDLK-------------------------GKI 510
LNRQFLFR DV K+E+A +N D G
Sbjct: 456 LNRQFLFRSGDVSSMKAEIAVREAMLLNEDFLKVPRRADSEEPERGVSEMTNGISCIGSA 515
Query: 511 EPKID----KVGAETENIFNDAFWNQLDFVTNALDNVDARTYVDRRCVFYKKPLLESGTL 566
+P + K G ETE +F+D F+ +D V ALDNVDAR YVD RCV +K ++++GT
Sbjct: 516 QPNLIYYNLKAGKETETVFSDRFFQSVDVVATALDNVDARVYVDGRCVVNRKFMVDAGTS 575
Query: 567 GTKGNTQVVIPNLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFSDAAE 626
GTKGN QVV+P TESY SS+DPPEKSIPLCT+++FP I+HTI WA+S F+ F D
Sbjct: 576 GTKGNVQVVVPFHTESYGSSQDPPEKSIPLCTIKNFPYAIEHTIEWARSEFEFKFHDEIL 635
Query: 627 NVNLYLTQPNFVEQTLKQAPDAKGILESISDCLNNRPYNFEDCVKWARLEFEKKFSYDIQ 686
+ YL++ E T ++ + + E++ D ++ P N ++C++ L F K F I+
Sbjct: 636 LIKEYLSREK--EGTSEEEREEEPSNEAMEDVVDKIPTNGKECIRNGILLFVKLFHTSIK 693
Query: 687 QFLYNFPKDATTSTGEPFWSGPKRAPEPLVFNIENPDHFHFIVASANLRAFNYGLKGDDG 746
+ FP D+ T G+PFW PKR P + F++ N H F+ ++AN+ + N+G+K
Sbjct: 694 NLITAFPPDSKTKEGQPFWMPPKRPPMTVSFDVNNDLHILFVQSAANIFSLNFGIKQQIS 753
Query: 747 KPDINYYQSVLSKLIVPEFIPKADIKIQTNDDEP--DPNANNQLGGDVLENLAASLPDAS 804
K + + V ++++V E AD P DP+A
Sbjct: 754 KEMV--VEFVKNEILVEELSSAADNTCVEESPRPCIDPSA-------------------- 791
Query: 805 TLAGFQLIPVEFEKDDDTNHHIEFITAASNNRALNYSIEPADRQKTKFIAGRIIPAIATT 864
++P FEKDDDTN H++F+ AA+N RA+NY I+ ADR K IAGRIIPAIATT
Sbjct: 792 ------IVPCIFEKDDDTNFHVDFLYAAANLRAINYKIKQADRLTVKGIAGRIIPAIATT 845
Query: 865 TALVTGLVNLELYKVVAGKTDIEQYKNGFVNLALPFFGFSEPIASQKGKY---NDKTFDK 921
TA+V+GL LE+ K G D ++KN F+NLALPFF ++P+ K Y N K
Sbjct: 846 TAVVSGLAVLEMIKYALG-VDYTKHKNSFLNLALPFFASTDPVEPVKHSYKIENKKYTFT 904
Query: 922 IWDRFDIQGDITLRELIDHFNKEEGLEITMVSYDVSLLYASFFPPKKLKDRMDLPITEVV 981
+W+R + + D L ++ F + +I+MV+ SL+Y F K D ++ + E+V
Sbjct: 905 LWNRLEYK-DSKLGTILKAFEIQFKRKISMVTAGNSLIYWDF--DSKYADNLEKTVGELV 961
Query: 982 KLVTKKEILSHVKTMILEFCCEDKEGE 1008
+ ++L+ +D EGE
Sbjct: 962 NRRPDEMF------VVLDVITDDDEGE 982
>HsM8922684 [O] KOG2012 Ubiquitin activating enzyme UBA1
Length = 459
Score = 291 bits (745), Expect = 4e-78
Identities = 178/458 (38%), Positives = 259/458 (55%), Gaps = 16/458 (3%)
Query: 566 LGTKGNTQVVIPNLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFSDAA 625
+GTKG+T+V++P+LTESY+S RDPPE+ IP CTL+SFP I+HTI WA+ F+ FS
Sbjct: 1 MGTKGHTEVIVPHLTESYNSHRDPPEEEIPFCTLKSFPAAIEHTIQWARDKFESSFSHKP 60
Query: 626 ENVNLYLTQPNFVEQTLKQAPDAKGI--LESISDCLNNRPYNFEDCVKWARLEFEKKFSY 683
N + + E+ L++ + + L+ RP N+ CV+ ARL+FEK F++
Sbjct: 61 SLFNKFWQTYSSAEEVLQKIQSGHSLEGCFQVIKLLSRRPRNWSQCVELARLKFEKYFNH 120
Query: 684 DIQQFLYNFPKDATTSTGEPFWSGPKRAPEPLVFNIENPDHFHFIVASANLRAFNYGLKG 743
Q L+ FP D G FW PKR P P+ F++ P H F+ +A L A Y +
Sbjct: 121 KALQLLHCFPLDIRLKDGSLFWQSPKRPPSPIKFDLNEPLHLSFLQNAAKLYATVYCIPF 180
Query: 744 DDGKPDINYYQSVLSKLIVPEFIPKADIKIQTNDD--EPD--PNANNQLGGDVLENLAAS 799
+ + ++LS++ + EF P + + T++ +PD P ++ + + A
Sbjct: 181 AEEDLSADALLNILSEVKIQEFKPSNKV-VHTDETARKPDHVPISSEDERNAIFQLEKAI 239
Query: 800 LPDASTLAGFQLIPVEFEKDDDTNHHIEFITAASNNRALNYSIEPADRQKTKFIAGRIIP 859
L + +T + Q+ + FEKDDD N HI+FITAASN RA YSIEPADR KTK IAG+IIP
Sbjct: 240 LSNEATKSDLQMAVLSFEKDDDHNGHIDFITAASNLRAKMYSIEPADRFKTKRIAGKIIP 299
Query: 860 AIATTTALVTGLVNLELYKVVAGKTDIEQYKNGFVNLALPFFGFSEPIASQKGKYNDKTF 919
AIATTTA V+GLV LE+ KV G E YKN F+NLA+P F+E +K K +
Sbjct: 300 AIATTTATVSGLVALEMIKVTGG-YPFEAYKNCFLNLAIPIVVFTETTEVRKTKIRNGIS 358
Query: 920 DKIWDRFDIQG--DITLRELIDHFNKEEGLEITMVSYDVSLLYASFFPPKKLKDRMDLPI 977
IWDR+ + G D TL + I+ ++ G+E TMV V +LY P R+ L +
Sbjct: 359 FTIWDRWTVHGKEDFTLLDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGH--AKRLKLTM 416
Query: 978 TEVVKLVTKKEILSHVKTMILEFCCEDKEGEDVEVPYV 1015
++VK T+K+ + + + F + ED+ P V
Sbjct: 417 HKLVKPTTEKKYVD----LTVSFAPDIDGDEDLPGPPV 450
>At2g21470 [O] KOG2013 SMT3/SUMO-activating complex catalytic component UBA2
Length = 700
Score = 175 bits (444), Expect = 3e-43
Identities = 147/467 (31%), Positives = 214/467 (45%), Gaps = 69/467 (14%)
Query: 426 QKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPK 485
Q I KV +VG+G IGCE+LK AL G I + D D+IE SNLNRQFLFR
Sbjct: 7 QSAIKGAKVLMVGAGGIGCELLKTLALSGFED-----IHIIDMDTIEVSNLNRQFLFRRS 61
Query: 486 DVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENI-FNDAFWNQLDFVTNALDNVD 544
VG++K++VA DAV P++ I A +N F+ F+ Q D V N LDN+D
Sbjct: 62 HVGQSKAKVARDAVLRFRPNIN------IRSYHANVKNPEFDVDFFKQFDVVLNGLDNLD 115
Query: 545 ARTYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEKSIPLCTLRSFPN 604
AR +V+R C+ PL+ESGT G G V I TE Y P K+ P+CT+ S P
Sbjct: 116 ARRHVNRLCLAADVPLVESGTTGFLGQVTVHIKGKTECYECQTKPAPKTYPVCTITSTPT 175
Query: 605 KIDHTIAWAKS-LFQGYFSDAAENVNLYLTQPNFVEQTLKQAPDAKGILESISDCLNNRP 663
K H I WAK LF F D ++ +L + N + + + + + E D
Sbjct: 176 KFVHCIVWAKDLLFAKLFGDKNQDNDLNVRSNN----SASSSKETEDVFERSED------ 225
Query: 664 YNFEDCVKWARLEFEKKFSYDIQQFLYNFPKDATTSTGEPFWSGPKRAPEPLVFNIENPD 723
ED ++ R ++ F +I+ L N E W +R P P+ P+
Sbjct: 226 ---EDIEQYGRKIYDHVFGSNIEAALSN----------EETWKN-RRRPRPIYSKDVLPE 271
Query: 724 HFHFIVASANLRAFNYGLKGDDGKPDINYYQSVLSKLIVPEFIPKADIKIQTNDDEPDPN 783
+ N N + D ++ +P +K N E
Sbjct: 272 S----LTQQNGSTQNCSVTDGD---------------LMVSAMPSLGLK---NPQELWGL 309
Query: 784 ANNQLGGDVLENLAASLPDASTLAGFQLIPVEFEKDDDTNHHIEFITAASNNRALNYSIE 843
N L +E L G + F+KDD +EF+TAA+N RA ++ I
Sbjct: 310 TQNSL--VFIEALKLFFAKRKKEIGH----LTFDKDDQL--AVEFVTAAANIRAESFGIP 361
Query: 844 PADRQKTKFIAGRIIPAIATTTALVTGLVNLELYKVVAGKTDIEQYK 890
+ K IAG I+ A+ATT A++ GL+ +E KV+ K D+++++
Sbjct: 362 LHSLFEAKGIAGNIVHAVATTNAIIAGLIVIEAIKVL--KKDVDKFR 406
>Hs4885649 [O] KOG2013 SMT3/SUMO-activating complex catalytic component UBA2
Length = 640
Score = 166 bits (420), Expect = 2e-40
Identities = 149/476 (31%), Positives = 219/476 (45%), Gaps = 70/476 (14%)
Query: 424 EFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFR 483
E + +A +V +VG+G IGCE+LKN L G + I + D D+I+ SNLNRQFLF+
Sbjct: 10 ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSH-----IDLIDLDTIDVSNLNRQFLFQ 64
Query: 484 PKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNALDNV 543
K VGR+K++VA ++V P K I D + N+ F+ Q V NALDN
Sbjct: 65 KKHVGRSKAQVAKESVLQFYP--KANIVAYHDSIMNPDYNV---EFFRQFILVMNALDNR 119
Query: 544 DARTYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEKSIPLCTLRSFP 603
AR +V+R C+ PL+ESGT G G + +TE Y P +++ P CT+R+ P
Sbjct: 120 AARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTP 179
Query: 604 NKIDHTIAWAKSLFQGYF--SDAAENVNLYLTQPNFVEQTLKQAPDAKGILESISDCLNN 661
++ H I WAK LF F DA + V+ P + + A+ E
Sbjct: 180 SEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPEAAWEPTEAEARARASNED------- 232
Query: 662 RPYNFEDCVKWARLEFEKKFSYD-IQQFLYNFPKDAT-TSTGEPFWSGPKRAPEPLVFNI 719
D + + E+ K YD ++ F F D T + W ++ P PL +
Sbjct: 233 -----GDIKRISTKEWAKSTGYDPVKLFTKLFKDDIRYLLTMDKLWR-KRKPPVPLDW-A 285
Query: 720 ENPDHFHFIVASANLRAFNYGLKGDDGKPDINYYQSVLSKLIVPEFIPKADIKIQTNDDE 779
E AS GLK D D+ Y + SK I
Sbjct: 286 EVQSQGEETNASDQQNEPQLGLK-DQQVLDVKSYARLFSKSI------------------ 326
Query: 780 PDPNANNQLGGDVLENLAASLPDASTLAGFQLIPVEFEKDDDTNHHIEFITAASNNRALN 839
E L L + G +LI ++KDD + ++F+T+A+N R
Sbjct: 327 --------------ETLRVHLAEKGD--GAELI---WDKDDPS--AMDFVTSAANLRMHI 365
Query: 840 YSIEPADRQKTKFIAGRIIPAIATTTALVTGLVNLELYKVVAGKTDIEQYKNGFVN 895
+S+ R K +AG IIPAIATT A++ GL+ LE K+++GK I+Q + F+N
Sbjct: 366 FSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGK--IDQCRTIFLN 419
>7295159_1 [O] KOG2013 SMT3/SUMO-activating complex catalytic component UBA2
Length = 731
Score = 165 bits (418), Expect = 3e-40
Identities = 135/478 (28%), Positives = 214/478 (44%), Gaps = 76/478 (15%)
Query: 420 VFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQ 479
VF Q+ + KV +VG+G IGCE+LKN L G I + D D+I+ SNLNRQ
Sbjct: 8 VFPPTLQELVKKSKVLVVGAGGIGCEVLKNLVLSGFTD-----IEIIDLDTIDLSNLNRQ 62
Query: 480 FLFRPKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNA 539
FLF + VG++K+ VA ++ + NPD KI D V T + F+ + D V +A
Sbjct: 63 FLFHREHVGKSKARVARESALSFNPD--AKITAYHDSV---TSTDYGVNFFKKFDLVLSA 117
Query: 540 LDNVDARTYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEKSIPLCTL 599
LDN AR +V+R C+ PL+ESGT G G +++ LT+ Y + ++S P CT+
Sbjct: 118 LDNRAARNHVNRMCLNADVPLIESGTAGYNGQVELIKRGLTQCYECTPKDKQRSFPGCTI 177
Query: 600 RSFPNKIDHTIAWAKSLFQGYFSDAAENVNLYLTQPNFVEQTLKQAPDAKGILESISDCL 659
R+ P++ H I WAK LF F ++ E+ ++ P+ + PDAK
Sbjct: 178 RNTPSEPIHCIVWAKHLFNQLFGESLEDEDI---SPDAAD------PDAK---------- 218
Query: 660 NNRPYNFEDCVKWARLEFEKKFSYDIQQFLYNFPKDATTSTGEPFWSGPKRAPEPLVFNI 719
KD GEP G ++ E
Sbjct: 219 ---------------------------------EKDGGDGNGEPKGDGKEKGEESKEEKE 245
Query: 720 ENPDHFHFIVASANLRAFNYGLKGDDGKPDINYYQSVLSKLIVPEFI---PKADIKIQTN 776
D + + N R + D GK ++ ++ L+ + KA + +Q +
Sbjct: 246 AKEDTANGNIMRINTRQWAKDCNYDAGKLFNKFFNEDITYLLRMSNLWKTRKAPVPVQWD 305
Query: 777 DDEPDPNANNQLGGDVLENLAASLPD-----ASTLAGFQLIPVEFEKDD------DTNHH 825
P+ ++ +Q + S+ + A++L ++ E DD D
Sbjct: 306 TLLPEGSSGDQKDVAKQHHKVWSIEECAQVFANSLKELSANFLKLEGDDTLAWDKDDQPA 365
Query: 826 IEFITAASNNRALNYSIEPADRQKTKFIAGRIIPAIATTTALVTGLVNLELYKVVAGK 883
++F+ A +N R+ + IE R + K +AG IIPAIATT A+ G+ + +KV+ K
Sbjct: 366 MDFVAACANVRSHIFDIERKSRFEIKSMAGNIIPAIATTNAITAGISVMRAFKVLEAK 423
>SPBC16H5.03c [O] KOG2013 SMT3/SUMO-activating complex catalytic component UBA2
Length = 628
Score = 157 bits (397), Expect = 8e-38
Identities = 116/357 (32%), Positives = 177/357 (49%), Gaps = 49/357 (13%)
Query: 423 LEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLF 482
+E + + KV LVG+G IGCE+LKN + G+ ++ + D D+I+ SNLNRQFLF
Sbjct: 17 VEALRNFKSAKVLLVGAGGIGCELLKNLLMSGVK-----EVHIIDLDTIDLSNLNRQFLF 71
Query: 483 RPKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNALDN 542
R K V + K+ VAA S+ NP++K + K E+ FN A++ Q D V NALDN
Sbjct: 72 RKKHVKQPKAIVAAKTASSFNPNVKLEAYHANIK-----EDRFNVAWFRQFDLVFNALDN 126
Query: 543 VDARTYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEKSIPLCTLRSF 602
+DAR +V+++C+ PL+ESGT G G QV+I TE Y + P K+ P+CT+RS
Sbjct: 127 LDARRHVNKQCLLASVPLIESGTTGFLGQVQVIIHGKTECYDCNPKEPPKTYPVCTIRST 186
Query: 603 PNKIDHTIAWAKS-LFQGYFSDAAE------NVNLYLTQPNFVEQTLKQAPDAKGILESI 655
P++ H + WAKS F FS+ E NV+ + + + ++ + + SI
Sbjct: 187 PSQPIHCVVWAKSYFFPQLFSNDQESDGIIDNVSANEMERREIAELARETTELNELRSSI 246
Query: 656 SDCLNNRPYNF-----EDCVK-------WARLEFEKKFSYDIQQFLYNFPKDATTSTGEP 703
N F +D V+ W K+ SY + L N K + E
Sbjct: 247 GQSDNGFEKIFTKMFTKDIVRLREVPDAWTYRSPPKELSY--SELLENAEKATSPWLNEQ 304
Query: 704 -FWS-----------------GPKRAPEPLVFNIENPDHFHFIVASANLRAFNYGLK 742
W+ K + + L F+ ++ D F+ A+ANLRA +G++
Sbjct: 305 NVWNVAESFAVLRDSIRRLALRSKSSKDDLSFDKDDKDTLDFVAAAANLRAHVFGIQ 361
Score = 54.7 bits (130), Expect = 7e-07
Identities = 42/169 (24%), Positives = 81/169 (47%), Gaps = 7/169 (4%)
Query: 26 EAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVALQDLSTQFFLSEQDIG 85
EA+ + + VL++G G+G E+ KN++++GVK + + D + L +L+ QF ++ +
Sbjct: 18 EALRNFKSAKVLLVGAGGIGCELLKNLLMSGVKEVHIIDLDTIDLSNLNRQFLFRKKHVK 77
Query: 86 QARDKVSQAKLAELNSYVPVK-----VLEGLEDVSQLSEFQVVVVTDTISLEEKVKLNEY 140
Q + V+ + N V ++ + E +V+ +F +V +L+ + +N+
Sbjct: 78 QPKAIVAAKTASSFNPNVKLEAYHANIKEDRFNVAWFRQFD-LVFNALDNLDARRHVNKQ 136
Query: 141 THSHGIGFISTETRGLFGNVFVDLGEEFTVIDTTGEE-PKTGIVSDIES 188
+ I + T G G V V + + D +E PKT V I S
Sbjct: 137 CLLASVPLIESGTTGFLGQVQVIIHGKTECYDCNPKEPPKTYPVCTIRS 185
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/78 (39%), Positives = 45/78 (56%), Gaps = 4/78 (5%)
Query: 814 VEFEKDDDTNHHIEFITAASNNRALNYSIEPADRQKTKFIAGRIIPAIATTTALVTGLVN 873
+ F+KDD ++F+ AA+N RA + I+ K +AG IIPAIATT A++ GL
Sbjct: 334 LSFDKDDKDT--LDFVAAAANLRAHVFGIQQLSEFDIKQMAGNIIPAIATTNAVIAGLCI 391
Query: 874 LELYKVVAGKTDIEQYKN 891
+ KV+ G D+ KN
Sbjct: 392 TQAIKVLQG--DLNDLKN 407
>YDR390c [O] KOG2013 SMT3/SUMO-activating complex catalytic component UBA2
Length = 636
Score = 150 bits (378), Expect = 1e-35
Identities = 137/471 (29%), Positives = 216/471 (45%), Gaps = 84/471 (17%)
Query: 413 RYDNQISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIE 472
R + +++ G + K++ + + LVG+G IG E+LK+ L+ G+I + D D+I+
Sbjct: 3 RETSLVTIIGEDSYKKLRSSRCLLVGAGGIGSELLKDIILMEF-----GEIHIVDLDTID 57
Query: 473 KSNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQ 532
SNLNRQFLFR KD+ + KS A AV N K+ P V + F ++ Q
Sbjct: 58 LSNLNRQFLFRQKDIKQPKSTTAVKAVQHFN---NSKLVPYQGNV--MDISTFPLHWFEQ 112
Query: 533 LDFVTNALDNVDARTYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEK 592
D + NALDN+ AR YV++ F PL+ESGT G G Q +IP TE + ++ K
Sbjct: 113 FDIIFNALDNLAARRYVNKISQFLSLPLIESGTAGFDGYMQPIIPGKTECFECTKKETPK 172
Query: 593 SIPLCTLRSFPNKIDHTIAWAKSLFQGYFSDAAENVNLYLTQPNFVEQTLKQAPDAKGIL 652
+ P+CT+RS P++ H I WAK+ +L F +T D
Sbjct: 173 TFPVCTIRSTPSQPIHCIVWAKN---------------FLFNQLFASETSGNEDD----- 212
Query: 653 ESISDCLNNRPYNFEDCVKWARLEFEKKFSYDIQQFLYNFPKDATTSTGEPFWSGPKRAP 712
NN+ + +D + R++ E Y++Q+ + + +DA+ R P
Sbjct: 213 -------NNQDWGTDDAEEIKRIKQETNELYELQKIIIS--RDAS------------RIP 251
Query: 713 EPLVFNIENPDHFHFIVASANLRAFNYGLKGDDGKPDINYYQSVLSKLIVPEFIPKADIK 772
E + N + ++A NL KP +P +D +
Sbjct: 252 E--ILNKLFIQDINKLLAIENLWKTR-------TKP-----------------VPLSDSQ 285
Query: 773 IQTNDDEPDPNANNQLG--GDVLENLAASLPDASTLAGFQLIPVEFEKDD-DTNHHIEFI 829
I T + +A+N +G + + N + +EF+KDD DT +EF+
Sbjct: 286 INT-PTKTAQSASNSVGTIQEQISNFINITQKLMDRYPKEQNHIEFDKDDADT---LEFV 341
Query: 830 TAASNNRALNYSIEPADRQKTKFIAGRIIPAIATTTALVTGLVNLELYKVV 880
A+N R+ ++I K IAG IIPAIATT A+V G +L +V+
Sbjct: 342 ATAANIRSHIFNIPMKSVFDIKQIAGNIIPAIATTNAIVAGASSLISLRVL 392
>Hs19923744 [O] KOG2015 NEDD8-activating complex catalytic component UBA3
Length = 463
Score = 122 bits (307), Expect = 2e-27
Identities = 71/198 (35%), Positives = 110/198 (54%), Gaps = 26/198 (13%)
Query: 433 KVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKDVGRNKS 492
KV ++G+G +GCE+LKN AL G +I V D D+I+ SNLNRQFLFRPKD+GR K+
Sbjct: 71 KVLVIGAGGLGCELLKNLALSGFR-----QIHVIDMDTIDVSNLNRQFLFRPKDIGRPKA 125
Query: 493 EVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNALDNVDARTYVDRR 552
EVAA+ ++ P+ + P K+ FND F+ Q + LD++ AR +++
Sbjct: 126 EVAAEFLNDRVPNC--NVVPHFYKI-----QDFNDTFYRQFHIIVCGLDSIIARRWINGM 178
Query: 553 CVFYKK------------PLLESGTLGTKGNTQVVIPNLTESYSSSRD--PPEKSIPLCT 598
+ PL++ GT G KGN +V++P +T + + PP+ + P+CT
Sbjct: 179 LISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCT 238
Query: 599 LRSFPNKIDHTIAWAKSL 616
+ S P +H I + + L
Sbjct: 239 IASMPRLPEHCIEYVRML 256
>CE25131 [O] KOG2013 SMT3/SUMO-activating complex catalytic component UBA2
Length = 438
Score = 122 bits (307), Expect = 2e-27
Identities = 75/201 (37%), Positives = 109/201 (53%), Gaps = 11/201 (5%)
Query: 424 EFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFR 483
E ++I K+ ++G+G IGCE+LKN A+ G K+ V D D+I+ SNLNRQFLFR
Sbjct: 6 EKHEKIVQSKILVIGAGGIGCELLKNLAVTGFR-----KVHVIDLDTIDISNLNRQFLFR 60
Query: 484 PKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNALDNV 543
+ V +K+ A V P +IE D + E +N F+ D V NALDN
Sbjct: 61 KEHVSSSKAATATQVVKQFCP----QIELTFDH-DSIFEKKYNMEFFQAYDIVLNALDNR 115
Query: 544 DARTYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEK-SIPLCTLRSF 602
AR YV+R C +PL++SG+ G G V++ TE Y P ++ + P CT+R+
Sbjct: 116 AARNYVNRMCHAANRPLIDSGSGGYFGQVSVIMRGKTECYECVDKPVQQTTYPGCTIRNT 175
Query: 603 PNKIDHTIAWAKSLFQGYFSD 623
P++ H WAK +F F +
Sbjct: 176 PSEHIHCTVWAKHVFNQLFGE 196
>CE25130 [O] KOG2013 SMT3/SUMO-activating complex catalytic component UBA2
Length = 456
Score = 118 bits (296), Expect = 4e-26
Identities = 74/197 (37%), Positives = 108/197 (54%), Gaps = 12/197 (6%)
Query: 429 IANLKVF-LVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKDV 487
I+ + +F ++G+G IGCE+LKN A+ G K+ V D D+I+ SNLNRQFLFR + V
Sbjct: 28 ISKISIFQVIGAGGIGCELLKNLAVTGFR-----KVHVIDLDTIDISNLNRQFLFRKEHV 82
Query: 488 GRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNALDNVDART 547
+K+ A V P +IE D + E +N F+ D V NALDN AR
Sbjct: 83 SSSKAATATQVVKQFCP----QIELTFDH-DSIFEKKYNMEFFQAYDIVLNALDNRAARN 137
Query: 548 YVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEK-SIPLCTLRSFPNKI 606
YV+R C +PL++SG+ G G V++ TE Y P ++ + P CT+R+ P++
Sbjct: 138 YVNRMCHAANRPLIDSGSGGYFGQVSVIMRGKTECYECVDKPVQQTTYPGCTIRNTPSEH 197
Query: 607 DHTIAWAKSLFQGYFSD 623
H WAK +F F +
Sbjct: 198 IHCTVWAKHVFNQLFGE 214
>Hs4885585 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 component
Length = 346
Score = 116 bits (291), Expect = 2e-25
Identities = 105/388 (27%), Positives = 171/388 (44%), Gaps = 70/388 (18%)
Query: 10 EIDESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVA 69
E + + Y RQ+ + G EA +++ S VL++GLKGLG EIAKN++LAGVK LT+ D V
Sbjct: 13 EEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVT 72
Query: 70 LQDLSTQFFLSEQDIGQARDKVSQAKLAELNSYVPVKVLEGLEDV-----SQLSEFQVVV 124
+D QF + +G+ R + S + LN V VKV ED+ S ++F V
Sbjct: 73 PEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKV--DTEDIEKKPESFFTQFDAVC 130
Query: 125 VTDTISLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDTTGEEPKTGIVS 184
+T S + VK+++ H + I F + + G G F +LGE + E+ K VS
Sbjct: 131 LT-CCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEH----EFVEEKTKVAKVS 185
Query: 185 DIESDGTVTMLDDNRHGLEDGNYVKFSEVEGLEKLNDGTPYKVEVLGPFAFKIGSVKDLG 244
G+EDG K ++++ E
Sbjct: 186 ---------------QGVEDGPDTKRAKLDSSET-------------------------- 204
Query: 245 TYKKGGLFTEVKMPQKLTFKSLRESLATPEFLYSDFAKFETTAQLHLGFQALHQFQVRHQ 304
T VK +K+ F ++E+L A + T + Q L +F+
Sbjct: 205 --------TMVK--KKVVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKG 254
Query: 305 GELPRPFYEEDSNELVKLVIDLATQQPEVLGSEGKVDEKLITELANQARGDIPGIVAFFG 364
+ YEEDS L+++ + +VL S G + L + ++ + A G
Sbjct: 255 RDPSSDTYEEDSELLLQI-------RNDVLDSLGISPDLLPEDFVRYCFSEMAPVCAVVG 307
Query: 365 GLVAQEVLKASSGKFTPIKQYMYFDSIE 392
G++AQE++KA S + P + +FD ++
Sbjct: 308 GILAQEIVKALSQRDPPHNNFFFFDGMK 335
Score = 67.8 bits (164), Expect = 8e-11
Identities = 43/142 (30%), Positives = 72/142 (50%), Gaps = 12/142 (8%)
Query: 412 SRYDNQISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSI 471
++YD QI ++GLE QKR+ +V LVG +G E+ KN L G+ + + D++ +
Sbjct: 17 AQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKG-----LTMLDHEQV 71
Query: 472 EKSNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWN 531
+ QFL R VGRN++E + + +NP ++ K+D E + ++F+
Sbjct: 72 TPEDPGAQFLIRTGSVGRNRAEASLERAQNLNP----MVDVKVDTEDIEKK---PESFFT 124
Query: 532 QLDFVTNALDNVDARTYVDRRC 553
Q D V + D VD+ C
Sbjct: 125 QFDAVCLTCCSRDVIVKVDQIC 146
>7303261 [O] KOG2015 NEDD8-activating complex catalytic component UBA3
Length = 450
Score = 113 bits (282), Expect = 2e-24
Identities = 66/197 (33%), Positives = 108/197 (54%), Gaps = 27/197 (13%)
Query: 433 KVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKDVGRNKS 492
+V ++G+G +GCE+LK+ AL+G G + V D D+IE SNLNRQFLFR D+G +K+
Sbjct: 50 QVLIIGAGGLGCELLKDLALMGF-----GNLHVIDMDTIELSNLNRQFLFRRTDIGASKA 104
Query: 493 EVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNALDNVDARTYVDRR 552
E AA ++A P ++ P K+ F+++F+ Q V LD++ AR +++
Sbjct: 105 ECAARFINARVPTC--RVTPHFKKI-----QDFDESFYQQFHLVVCGLDSIVARRWINGM 157
Query: 553 CVFYKK-------------PLLESGTLGTKGNTQVVIPNLTESYSSSRD--PPEKSIPLC 597
+ + P+++ GT G KGN +V++P T + D PP+ + PLC
Sbjct: 158 LLSMLRYEEDGTIDTSSIVPMIDGGTEGFKGNARVILPGFTACIECTLDLFPPQVNYPLC 217
Query: 598 TLRSFPNKIDHTIAWAK 614
T+ + P +H I + K
Sbjct: 218 TIANTPRLPEHCIEYVK 234
>At5g19180 [O] KOG2015 NEDD8-activating complex catalytic component UBA3
Length = 477
Score = 105 bits (262), Expect = 4e-22
Identities = 68/197 (34%), Positives = 108/197 (54%), Gaps = 27/197 (13%)
Query: 432 LKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKDVGRNK 491
+++ ++G+G +GCE+LK+ AL G + + V D D IE +NLNRQFLFR +DVG+ K
Sbjct: 47 VRILVIGAGGLGCELLKDLALSGFRN-----LEVIDMDRIEVTNLNRQFLFRIEDVGKPK 101
Query: 492 SEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNALDNVDARTYVDR 551
+EVAA V M +I P ++ E + I F+N + + LD+++AR Y++
Sbjct: 102 AEVAAKRV--MERVSGVEIVPHFSRI--EDKEI---EFYNDFNIIALGLDSIEARKYING 154
Query: 552 -RCVFYK------------KPLLESGTLGTKGNTQVVIPNLTESYSSS--RDPPEKSIPL 596
C F + KP+++ GT G KG+ +V++P +T + + PP+ PL
Sbjct: 155 VACGFLEYNEDDTPKRETIKPMVDGGTEGFKGHARVILPGVTPCFECTIYLFPPQVKFPL 214
Query: 597 CTLRSFPNKIDHTIAWA 613
CTL P H I +A
Sbjct: 215 CTLAETPRNAAHCIEYA 231
>SPAC24H6.12c [O] KOG2015 NEDD8-activating complex catalytic component UBA3
Length = 444
Score = 103 bits (258), Expect = 1e-21
Identities = 64/197 (32%), Positives = 102/197 (51%), Gaps = 19/197 (9%)
Query: 424 EFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFR 483
E K + K+ ++G+G +GCE+LK+ AL G + V D D+I+ +NLNRQFLF
Sbjct: 37 ETLKSAFSSKILIIGAGGLGCEILKDLALSGFRD-----LSVIDMDTIDITNLNRQFLFN 91
Query: 484 PKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNALDNV 543
++ K+ VAA + P + P K+ +T F+ + + LD+V
Sbjct: 92 ESNIDEPKANVAASMIMKRIPST--VVTPFYGKIQDKTIE-----FYKEFKLIICGLDSV 144
Query: 544 DARTYVDRRCVFYKK-----PLLESGTLGTKGNTQVVIPNLTESYSSSRD--PPEKSIPL 596
+AR +++ V K PL++ G+ G KG +V+IP +T Y S D P+ S P+
Sbjct: 145 EARRWINSTLVAIAKTGDLIPLVDGGSEGLKGQARVIIPTITSCYECSLDMLTPKISYPI 204
Query: 597 CTLRSFPNKIDHTIAWA 613
CTL + P +H + WA
Sbjct: 205 CTLANTPRLPEHCVEWA 221
>ECU02g1340 [O] KOG2013 SMT3/SUMO-activating complex catalytic component UBA2
Length = 429
Score = 103 bits (256), Expect = 2e-21
Identities = 66/187 (35%), Positives = 101/187 (53%), Gaps = 13/187 (6%)
Query: 433 KVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKDVGRNKS 492
++ +VG G IGCE+LK A L S I + D+D+++ SNLNRQF F D+G++K+
Sbjct: 5 RILVVGCGGIGCELLKLLAREKLES-----ITLVDSDTVDLSNLNRQFFFNRDDIGKSKA 59
Query: 493 EVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQLDFVTNALDNVDARTYVDRR 552
VAA +N + + P + TE F+ F+ V + LDN++AR+YV++R
Sbjct: 60 TVAAGIFKKLNE--RCDVFPICADI---TE--FDARFFAGYRTVYSCLDNIEARSYVNQR 112
Query: 553 CVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAW 612
C + PL++ G G KG N +E + + +CT+RS P +H IAW
Sbjct: 113 CFISRTPLVDGGCGGFKGQAYYFDYN-SECFDCIPKKVSREHLVCTIRSRPTNFEHCIAW 171
Query: 613 AKSLFQG 619
AK +F G
Sbjct: 172 AKHVFLG 178
>CE04374 [O] KOG2015 NEDD8-activating complex catalytic component UBA3
Length = 437
Score = 103 bits (256), Expect = 2e-21
Identities = 80/261 (30%), Positives = 122/261 (46%), Gaps = 43/261 (16%)
Query: 411 NSRYDNQISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDS 470
+S Y V G E + + N K+ ++G+G +GCE+LKN AL G + I V D D+
Sbjct: 22 DSAYKVPWFVPGPENFEALQNTKILVIGAGGLGCELLKNLALSGFRT-----IEVIDMDT 76
Query: 471 IEKSNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKG--------KIEPKIDKVGAETE 522
I+ SNLNRQFLFR DVG++K+EVAA V + + +I+ G E
Sbjct: 77 IDVSNLNRQFLFRESDVGKSKAEVAAAFVQQRVVGCQNYFNFISIFRHNCRIEDKGQE-- 134
Query: 523 NIFNDAFWNQLDFVTNALDNVDARTYV----------------DRRCVFYKKPLLESGTL 566
F+ + + LD++ AR ++ D + P+++ GT
Sbjct: 135 ------FYRKFSIIICGLDSIPARRWINGMLCDLVLEMADGKPDENTII---PMIDGGTE 185
Query: 567 GTKGNTQVVIPNLTESYSSSRD--PPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFSDA 624
G KGN +V+ P T + D PP+ + PLCT+ P +H I + K +
Sbjct: 186 GFKGNARVIYPKFTACIDCTLDLYPPQVNFPLCTIAHTPRLPEHCIEYIKVVVWPE-EKP 244
Query: 625 AENVNLYLTQPNFVEQTLKQA 645
E V+L P VE L++A
Sbjct: 245 FEGVSLDADDPIHVEWVLERA 265
Score = 58.2 bits (139), Expect = 7e-08
Identities = 26/82 (31%), Positives = 50/82 (60%)
Query: 13 ESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVALQD 72
+S Y +V G E +Q++ +L+IG GLG E+ KN+ L+G +++ + D + + +
Sbjct: 22 DSAYKVPWFVPGPENFEALQNTKILVIGAGGLGCELLKNLALSGFRTIEVIDMDTIDVSN 81
Query: 73 LSTQFFLSEQDIGQARDKVSQA 94
L+ QF E D+G+++ +V+ A
Sbjct: 82 LNRQFLFRESDVGKSKAEVAAA 103
>YPR066w [O] KOG2015 NEDD8-activating complex catalytic component UBA3
Length = 299
Score = 101 bits (252), Expect = 5e-21
Identities = 57/197 (28%), Positives = 105/197 (52%), Gaps = 26/197 (13%)
Query: 433 KVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKDVGRNKS 492
K+ ++G+G +GCE+LKN +L ++ + D D+IE +NLNRQFLF KD+G+ K+
Sbjct: 4 KILVLGAGGLGCEILKNLTMLSFVK----QVHIVDIDTIELTNLNRQFLFCDKDIGKPKA 59
Query: 493 EVAADAVSAMNPDLKGKIEPKIDKVGAETENI--FNDAFWNQLDFVTNALDNVDARTYVD 550
+VAA V+ P L +V A +++ +F+ F+ + LD ++ R +++
Sbjct: 60 QVAAQYVNTRFPQL---------EVVAHVQDLTTLPPSFYKDFQFIISGLDAIEPRRFIN 110
Query: 551 RRCVFYKK--------PLLESGTLGTKGNTQVVIPNLTESYSSSRD---PPEKSIPLCTL 599
V P ++ GT G KG+ + +IP +T + S D + ++P+CT+
Sbjct: 111 ETLVKLTLESNYEICIPFIDGGTEGLKGHVKTIIPGITACWECSIDTLPSQQDTVPMCTI 170
Query: 600 RSFPNKIDHTIAWAKSL 616
+ P I+H + + ++
Sbjct: 171 ANNPRCIEHVVEYVSTI 187
>SPAC4C5.04 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 component
Length = 307
Score = 95.9 bits (237), Expect = 3e-19
Identities = 65/182 (35%), Positives = 93/182 (50%), Gaps = 6/182 (3%)
Query: 1 MTNIKVDGEEIDESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSL 60
M N ++ EEI +LY RQ+ + G A ++ S VL+I L EIAKN+VL+G+ L
Sbjct: 1 MGNHNINAEEI--ALYDRQIRLWGFNAQQALKQSRVLLITASPLANEIAKNLVLSGIGKL 58
Query: 61 TLYDPSAVALQDLSTQFFLSEQDIGQARDKVSQAKLAELNSYVPVKVLEGL---EDVSQL 117
+ D V +D+ QFF+ DIGQ R V + KL ELN V + L D ++
Sbjct: 59 CVLDSMTVYEKDVEEQFFIEASDIGQLRANVFKKKLHELNPLVEIDTDTSLISEIDEGKI 118
Query: 118 SEFQVVVVTDTISLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDTTGEE 177
S+F +V+ T + EE ++NE T F +T GL+G F DL ID +
Sbjct: 119 SKFSMVIATQ-LDYEEFCRINELTRICNASFYATSCFGLYGFAFCDLINHNFAIDRVVDN 177
Query: 178 PK 179
K
Sbjct: 178 TK 179
>YPR180w [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 component
Length = 347
Score = 91.7 bits (226), Expect = 5e-18
Identities = 59/194 (30%), Positives = 106/194 (54%), Gaps = 6/194 (3%)
Query: 3 NIKVDGEEIDE-SLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLT 61
++KV+ DE +LY RQ+ + G A M+ + VL+I L +G EI K++VL+G+ LT
Sbjct: 2 DMKVEKLSEDEIALYDRQIRLWGMTAQANMRSAKVLLINLGAIGSEITKSIVLSGIGHLT 61
Query: 62 LYDPSAVALQDLSTQFFLSEQDIGQARDKVSQAKLAELNSYVPVKV-LEGLEDVSQ--LS 118
+ D V +DL +QFF+ +D+GQ + ++ ++ +LN + + + L++ +
Sbjct: 62 ILDGHMVTEEDLGSQFFIGSEDVGQWKIDATKERIQDLNPRIELNFDKQDLQEKDEEFFQ 121
Query: 119 EFQVVVVTDTISLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDTTGEEP 178
+F +VV T+ + ++E +K+N T I + GLF VF+DL EF D +
Sbjct: 122 QFDLVVATE-MQIDEAIKINTLTRKLNIPLYVAGSNGLFAYVFIDL-IEFISEDEKLQSV 179
Query: 179 KTGIVSDIESDGTV 192
+ V I S+ ++
Sbjct: 180 RPTTVGPISSNRSI 193
Score = 60.8 bits (146), Expect = 1e-08
Identities = 41/154 (26%), Positives = 72/154 (46%), Gaps = 12/154 (7%)
Query: 414 YDNQISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEK 473
YD QI ++G+ Q + + KV L+ GAIG E+ K+ L G+ G + + D + +
Sbjct: 16 YDRQIRLWGMTAQANMRSAKVLLINLGAIGSEITKSIVLSGI-----GHLTILDGHMVTE 70
Query: 474 SNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWNQL 533
+L QF +DVG+ K + + + +NP +IE DK + + ++ F+ Q
Sbjct: 71 EDLGSQFFIGSEDVGQWKIDATKERIQDLNP----RIELNFDKQDLQEK---DEEFFQQF 123
Query: 534 DFVTNALDNVDARTYVDRRCVFYKKPLLESGTLG 567
D V +D ++ PL +G+ G
Sbjct: 124 DLVVATEMQIDEAIKINTLTRKLNIPLYVAGSNG 157
>7299631 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 component
Length = 337
Score = 85.9 bits (211), Expect = 3e-16
Identities = 54/170 (31%), Positives = 89/170 (51%), Gaps = 4/170 (2%)
Query: 6 VDGEEIDESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDP 65
V+ E + LY RQ+ + G E+ +++ + +LI GL GLG EI KN++L+GV S+ L D
Sbjct: 12 VELTEAENELYDRQIRLWGLESQKRLRTAKILIAGLCGLGAEITKNIILSGVNSVKLLDD 71
Query: 66 SAVALQDLSTQFFLSEQDIGQARDKVSQAKLAELNSYVPVKV-LEGLEDVSQ--LSEFQV 122
V +D +QF + + + R + S + LN V + E L++ + +F V
Sbjct: 72 KDVTEEDFCSQFLVPRESLNTNRAEASLTRARALNPMVDISADREPLKEKTSEFFGQFDV 131
Query: 123 VVVTDTISLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVID 172
VVV + EE ++++ G+ FI+T+ G FG F L + V D
Sbjct: 132 VVVNGATN-EELLRIDTICRDLGVKFIATDVWGTFGFYFASLQKHSYVED 180
Score = 57.0 bits (136), Expect = 1e-07
Identities = 34/114 (29%), Positives = 58/114 (50%), Gaps = 7/114 (6%)
Query: 405 DTTKPINSRYDNQISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKII 464
+ T+ N YD QI ++GLE QKR+ K+ + G +G E+ KN L G+ S +
Sbjct: 13 ELTEAENELYDRQIRLWGLESQKRLRTAKILIAGLCGLGAEITKNIILSGVNS-----VK 67
Query: 465 VTDNDSIEKSNLNRQFLFRPKDVGRNKSEVAADAVSAMNP--DLKGKIEPKIDK 516
+ D+ + + + QFL + + N++E + A+NP D+ EP +K
Sbjct: 68 LLDDKDVTEEDFCSQFLVPRESLNTNRAEASLTRARALNPMVDISADREPLKEK 121
>At5g50680 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 component
Length = 320
Score = 75.1 bits (183), Expect = 5e-13
Identities = 56/172 (32%), Positives = 89/172 (51%), Gaps = 16/172 (9%)
Query: 6 VDGEEIDE---SLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTL 62
+DG+E+ E +LY RQ+ V G A ++ S+VL+ G+KG E KN+VLAGV S+TL
Sbjct: 1 MDGDELTEQETALYDRQIRVWGAGAQRRLSKSHVLVSGIKGTVAEFCKNIVLAGVGSVTL 60
Query: 63 YDPSAVALQDLSTQFFLSEQD---IGQARDKVSQAKLAELNSYVPVKVLEGLEDVSQL-- 117
D V + + F + + +G+ ++ L + N V V + +G D+S L
Sbjct: 61 LDDRLVTTEVFNANFLILPDENAYVGKTVAEICCDSLKDFNPMVHVSIEKG--DLSTLGV 118
Query: 118 ---SEFQVVVVTDTISLEEKVKLNEYTH--SHGIGFISTETRGLFGNVFVDL 164
+F VVV+ + S K +NE + + F + + RG G +FVDL
Sbjct: 119 DFFEKFDVVVIGYS-SRATKKAVNEKCRNLAKDVAFYTVDCRGSCGEIFVDL 169
>At5g50580 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 component
Length = 320
Score = 75.1 bits (183), Expect = 5e-13
Identities = 56/172 (32%), Positives = 89/172 (51%), Gaps = 16/172 (9%)
Query: 6 VDGEEIDE---SLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTL 62
+DG+E+ E +LY RQ+ V G A ++ S+VL+ G+KG E KN+VLAGV S+TL
Sbjct: 1 MDGDELTEQETALYDRQIRVWGAGAQRRLSKSHVLVSGIKGTVAEFCKNIVLAGVGSVTL 60
Query: 63 YDPSAVALQDLSTQFFLSEQD---IGQARDKVSQAKLAELNSYVPVKVLEGLEDVSQL-- 117
D V + + F + + +G+ ++ L + N V V + +G D+S L
Sbjct: 61 LDDRLVTTEVFNANFLILPDENAYVGKTVAEICCDSLKDFNPMVHVSIEKG--DLSTLGV 118
Query: 118 ---SEFQVVVVTDTISLEEKVKLNEYTH--SHGIGFISTETRGLFGNVFVDL 164
+F VVV+ + S K +NE + + F + + RG G +FVDL
Sbjct: 119 DFFEKFDVVVIGYS-SRATKKAVNEKCRNLAKDVAFYTVDCRGSCGEIFVDL 169
>CE05246 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 component
Length = 343
Score = 74.7 bits (182), Expect = 7e-13
Identities = 65/212 (30%), Positives = 96/212 (44%), Gaps = 15/212 (7%)
Query: 12 DESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVALQ 71
++++Y RQ+ + G EA K+++S VLIIG K LG E+AK + LAGV + L D V +
Sbjct: 7 EQAIYDRQIRLWGMEAQNKIRNSKVLIIGGKQLGAEVAKTLSLAGVDEMHLVDHRLVDTE 66
Query: 72 DLSTQFF--LSEQDIGQARDKVSQAKLAELNSYVPVKVLEGLEDV---------SQLSEF 120
++ F S + + S L LN V + ++E EDV L++F
Sbjct: 67 EIGMNFLYDASVDNSKMTKWAASYNFLYNLNRNVKLFIVE--EDVLSKNDSEIEEYLTKF 124
Query: 121 QVVVVTDTISLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDTTGEEPKT 180
+VVV D S E K+N H I FIS G G F D ++ +
Sbjct: 125 TLVVVLDE-SYERTAKVNNICRKHHIRFISGAIYGWIGYAFFDFDGHAYLVKAKSPDCLN 183
Query: 181 GIVSDIESDGTVTMLDDNRHGLEDGNYVKFSE 212
S+ TV +D+ LE +Y F E
Sbjct: 184 EEESETGKTSTVVTVDE-EFVLETFSYPSFVE 214
>CE01166 [O] KOG2016 NEDD8-activating complex APP-BP1/UBA5 component
Length = 525
Score = 74.7 bits (182), Expect = 7e-13
Identities = 56/189 (29%), Positives = 91/189 (47%), Gaps = 26/189 (13%)
Query: 16 YSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVALQDLST 75
Y RQ+ + G+E + ++ ++G L EI K++VLAGV+S + D + V D+
Sbjct: 10 YDRQVRLWGEEGQASIGSTSACVLGSDSLATEILKSLVLAGVQSFYVVDDAKVEQADIGQ 69
Query: 76 QFFLSEQDIGQARDKVSQAKLAELNSYV-------PVKVLEGLEDVSQLSEFQVVVVTDT 128
FFL DIG++R + + KL ELN V P L +EDV +L+ F VVV +
Sbjct: 70 NFFLHADDIGRSRAEATLEKLTELNPSVSGSASSQPPTAL-AMEDVEKLTTFSVVVAANQ 128
Query: 129 ISLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDTTGEEPKTGIVSDIES 188
NE I T T GL G + + + +E T+ ++ E P+ + D
Sbjct: 129 ---------NEE--------IDTTTFGLIGTIRICI-KEHTIANSHEENPRPDLRLDAPF 170
Query: 189 DGTVTMLDD 197
+ M+++
Sbjct: 171 SKLIEMINE 179
Score = 58.9 bits (141), Expect = 4e-08
Identities = 27/98 (27%), Positives = 56/98 (56%), Gaps = 5/98 (5%)
Query: 411 NSRYDNQISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDS 470
++RYD Q+ ++G E Q I + ++GS ++ E+LK+ L G+ S V D+
Sbjct: 7 STRYDRQVRLWGEEGQASIGSTSACVLGSDSLATEILKSLVLAGVQS-----FYVVDDAK 61
Query: 471 IEKSNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKG 508
+E++++ + F D+GR+++E + ++ +NP + G
Sbjct: 62 VEQADIGQNFFLHADDIGRSRAEATLEKLTELNPSVSG 99
>CE28320 [H] KOG2017 Molybdopterin synthase sulfurylase
Length = 402
Score = 73.9 bits (180), Expect = 1e-12
Identities = 49/173 (28%), Positives = 77/173 (44%), Gaps = 13/173 (7%)
Query: 404 ADTTKPINSRYDNQISV--FGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEG 461
A +K RY Q+ V FG+ QK + NL V +VG+G +GC + G+ G
Sbjct: 8 AGISKKDAGRYSRQLLVDDFGVSGQKNLKNLNVLIVGAGGLGCPVATYLGAAGI-----G 62
Query: 462 KIIVTDNDSIEKSNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAET 521
I + D D I NL+RQ ++ VG++K++ AD + N DL ++ ++
Sbjct: 63 TIGIVDYDHISLDNLHRQVAYKEDQVGKSKAQALADNIKLQNSDL----NVQVHNTSLDS 118
Query: 522 ENIFNDAFWNQLDFVTNALDNVDARTYVDRRCVFYKKPLLESGTLGTKGNTQV 574
N + + V + DNV R ++ CV PL+ L G V
Sbjct: 119 SNAMQ--LFKNYEIVCDCTDNVATRYLINDVCVLLNIPLVSGSALRWDGQLSV 169
>Hs20559018 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 component
Length = 377
Score = 73.2 bits (178), Expect = 2e-12
Identities = 86/347 (24%), Positives = 142/347 (40%), Gaps = 78/347 (22%)
Query: 36 VLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVALQDLSTQFFLSEQDIGQARDKVSQAK 95
VL+ G+KGLG EIAKN++LAGVK LT+ D ++ ++ QF + +G+ R + S +
Sbjct: 88 VLLAGMKGLGAEIAKNLILAGVKGLTMLDHKQISPEEPGAQFLIRIGSVGRNRAEASLER 147
Query: 96 LAELNSYVPVKVLEGLEDVSQLSEFQVVVVTDTISLEEKVKLNEYTHSHGIGFISTETRG 155
LN V VK+ ED+ + E D + ++ H + I F + +
Sbjct: 148 AQNLNPMVDVKL--DTEDIEKKPE-SFFTQFDAV--------DQICHKNSIKFFAGDVFS 196
Query: 156 LFGNVFVDLGEEFTVIDTTGEEPKTGIVSDIESDGTVTMLDDNRHGLEDGNYVKFSEVEG 215
G F +LGE + E+ K VS G+EDG K +++
Sbjct: 197 YHGYTFANLGEH----EFVEEKTKVAKVS---------------QGVEDGPDTKRVKLDS 237
Query: 216 LEKLNDGTPYKVEVLGPFAFKIGSVKDLGTYKKGGLFTEVKMPQKLTFKSLRESLATPEF 275
E T VK +K+ F ++E+L
Sbjct: 238 SET----------------------------------TMVK--KKVVFCPVKEALEVDWS 261
Query: 276 LYSDFAKFETTAQLHLGFQALHQFQVRHQGELPRPFYEEDSNELVKLVIDLATQQPEVLG 335
A + T H Q L +F+ + + EDS L+++ + +VL
Sbjct: 262 SKKAKAALKRTTSDHFLLQVLLKFRTDKGRDPSSDTHGEDSELLLQI-------RNDVLD 314
Query: 336 SEGKV-DEKLITELANQARGDIPGIVAFFGGLVAQEVLKASSGKFTP 381
S G + D + IT + ++ + A GG++AQE++KA S + P
Sbjct: 315 SLGIIPDPRFITYFFS----EMAPVCAVVGGILAQEIVKALSQQDPP 357
>At4g24940 [O] KOG2014 SMT3/SUMO-activating complex AOS1/RAD31 component
Length = 319
Score = 71.6 bits (174), Expect = 6e-12
Identities = 55/172 (31%), Positives = 86/172 (49%), Gaps = 16/172 (9%)
Query: 6 VDGEEIDE---SLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTL 62
+DGEE+ E +LY RQ+ V G A ++ +++L+ G+KG E KN+VLAGV S+TL
Sbjct: 1 MDGEELTEQETALYDRQIRVWGANAQRRLTKAHILVSGIKGTVAEFCKNIVLAGVGSVTL 60
Query: 63 YDPSAVALQDLSTQFFLSEQD---IGQARDKVSQAKLAELNSYVPVKVLEGLEDVSQL-- 117
D ++ L+ F + + G+ ++ L + N V V V +G D+S L
Sbjct: 61 MDDRLANMEALNANFLIPPDENVYSGKTVAEICSDSLKDFNPMVRVSVEKG--DLSMLGT 118
Query: 118 ---SEFQVVVVTDTISLEEKVKLNEYTH--SHGIGFISTETRGLFGNVFVDL 164
+F VVV+ S K +NE + F + + R G +FVDL
Sbjct: 119 DFFEQFDVVVI-GYGSRATKKYVNEKCRKLKKRVAFYTVDCRDSCGEIFVDL 169
Score = 51.2 bits (121), Expect = 8e-06
Identities = 38/158 (24%), Positives = 68/158 (42%), Gaps = 17/158 (10%)
Query: 405 DTTKPINSRYDNQISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKII 464
+ T+ + YD QI V+G Q+R+ + + G E KN L G+ G +
Sbjct: 5 ELTEQETALYDRQIRVWGANAQRRLTKAHILVSGIKGTVAEFCKNIVLAGV-----GSVT 59
Query: 465 VTDNDSIEKSNLNRQFLFRPKD---VGRNKSEVAADAVSAMNPDLKGKIEP-KIDKVGAE 520
+ D+ LN FL P + G+ +E+ +D++ NP ++ +E + +G +
Sbjct: 60 LMDDRLANMEALNANFLIPPDENVYSGKTVAEICSDSLKDFNPMVRVSVEKGDLSMLGTD 119
Query: 521 TENIFNDAFWNQLDFVTNALDNVDARTYVDRRCVFYKK 558
F+ Q D V + + YV+ +C KK
Sbjct: 120 --------FFEQFDVVVIGYGSRATKKYVNEKCRKLKK 149
>At1g05180 [O] KOG2016 NEDD8-activating complex APP-BP1/UBA5 component
Length = 540
Score = 70.9 bits (172), Expect = 1e-11
Identities = 47/164 (28%), Positives = 80/164 (48%), Gaps = 8/164 (4%)
Query: 16 YSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVALQDLST 75
Y RQL + G+ ++ +++ ++ G E KN+VL GV S+T+ D S V DL
Sbjct: 24 YDRQLRIWGEVGQAALEEASICLLNCGPTGSEALKNLVLGGVGSITVVDGSKVQFGDLGN 83
Query: 76 QFFLSEQDIGQARDKVSQAKLAELNSYVPVKVLEGLEDV------SQLSEFQVVVVTDTI 129
F + + +GQ++ K A L ELN V K +E D S S+F +V+ T +
Sbjct: 84 NFMVDAKSVGQSKAKSVCAFLQELNDSVNAKFIEENPDTLITTNPSFFSQFTLVIATQLV 143
Query: 130 SLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDT 173
+ +KL+ + + + GL G V + + +E +ID+
Sbjct: 144 E-DSMLKLDRICRDANVKLVLVRSYGLAGFVRISV-KEHPIIDS 185
Score = 55.5 bits (132), Expect = 4e-07
Identities = 49/203 (24%), Positives = 84/203 (41%), Gaps = 12/203 (5%)
Query: 412 SRYDNQISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSI 471
++YD Q+ ++G Q + + L+ G G E LKN L G+ G I V D +
Sbjct: 22 TKYDRQLRIWGEVGQAALEEASICLLNCGPTGSEALKNLVLGGV-----GSITVVDGSKV 76
Query: 472 EKSNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWN 531
+ +L F+ K VG++K A +V A +L + K + +T N +F++
Sbjct: 77 QFGDLGNNFMVDAKSVGQSK----AKSVCAFLQELNDSVNAKFIEENPDTLITTNPSFFS 132
Query: 532 QLDFVTNALDNVDARTYVDRRCVFYKKPLLESGTLGTKGNTQVVI---PNLTESYSSSRD 588
Q V D+ +DR C L+ + G G ++ + P + D
Sbjct: 133 QFTLVIATQLVEDSMLKLDRICRDANVKLVLVRSYGLAGFVRISVKEHPIIDSKPDHFLD 192
Query: 589 PPEKSIPLCTLRSFPNKIDHTIA 611
+ P L+SF ID ++
Sbjct: 193 DLRLNNPWPELKSFVETIDLNVS 215
>At2g32410 [O] KOG2016 NEDD8-activating complex APP-BP1/UBA5 component
Length = 523
Score = 69.7 bits (169), Expect = 2e-11
Identities = 46/164 (28%), Positives = 79/164 (48%), Gaps = 8/164 (4%)
Query: 16 YSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVALQDLST 75
Y RQL + G+ ++ +++ ++ G E KN+V+ G+ S+T+ D S V + DL
Sbjct: 8 YDRQLRIWGELGQSALETASICLLNCGPTGSEALKNLVIGGIGSITIVDGSKVEIGDLGN 67
Query: 76 QFFLSEQDIGQARDKVSQAKLAELNSYVPVKVLEGLEDV------SQLSEFQVVVVTDTI 129
F + + +GQ+R K L ELN V +E D S S+F +V+ T +
Sbjct: 68 NFMVDAKSVGQSRAKTVCGFLQELNDSVKANFVEENPDTLISTDPSFFSQFTLVIATQLV 127
Query: 130 SLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDT 173
+ VKL+ + + + GL G V + + +E T I+T
Sbjct: 128 E-DSMVKLDRICREANVMLVLARSYGLTGFVRISV-KEHTAIET 169
Score = 51.6 bits (122), Expect = 6e-06
Identities = 43/199 (21%), Positives = 83/199 (41%), Gaps = 12/199 (6%)
Query: 412 SRYDNQISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSI 471
++YD Q+ ++G Q + + L+ G G E LKN + G+ G I + D +
Sbjct: 6 TKYDRQLRIWGELGQSALETASICLLNCGPTGSEALKNLVIGGI-----GSITIVDGSKV 60
Query: 472 EKSNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWN 531
E +L F+ K VG+++++ + +N +K + +T + +F++
Sbjct: 61 EIGDLGNNFMVDAKSVGQSRAKTVCGFLQELNDSVKANFVEE----NPDTLISTDPSFFS 116
Query: 532 QLDFVTNALDNVDARTYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSS---SRD 588
Q V D+ +DR C L+ + + G G ++ + T + S D
Sbjct: 117 QFTLVIATQLVEDSMVKLDRICREANVMLVLARSYGLTGFVRISVKEHTAIETKPDHSLD 176
Query: 589 PPEKSIPLCTLRSFPNKID 607
+ P L+S+ ID
Sbjct: 177 DLRLNSPWPELKSYVESID 195
>Hs4502169 [O] KOG2016 NEDD8-activating complex APP-BP1/UBA5 component
Length = 534
Score = 66.6 bits (161), Expect = 2e-10
Identities = 50/167 (29%), Positives = 78/167 (45%), Gaps = 11/167 (6%)
Query: 8 GEEIDESLYSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSA 67
G+ + E Y RQL + G ++ ++V +I G EI KN+VL G+ S T+ D +
Sbjct: 5 GKLLKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQ 64
Query: 68 VALQDLSTQFFLSEQDIGQARDKVSQAKLAELNSYV--------PVKVLEGLEDVSQLSE 119
V+ +D FFL IG+ R + + L ELNS V P +L+ D S
Sbjct: 65 VSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLD--NDPSFFCR 122
Query: 120 FQVVVVTDTISLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGE 166
F VVV T + ++L + + I + T GL G + + + E
Sbjct: 123 FTVVVATQ-LPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKE 168
Score = 52.0 bits (123), Expect = 5e-06
Identities = 25/96 (26%), Positives = 49/96 (51%), Gaps = 5/96 (5%)
Query: 413 RYDNQISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIE 472
+YD Q+ ++G Q+ + + V L+ + A G E+LKN L G+ G + D + +
Sbjct: 12 KYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGI-----GSFTIIDGNQVS 66
Query: 473 KSNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKG 508
+ F + +G+N++E A + + +N D+ G
Sbjct: 67 GEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSG 102
>At5g55130 [H] KOG2017 Molybdopterin synthase sulfurylase
Length = 464
Score = 65.9 bits (159), Expect = 3e-10
Identities = 51/190 (26%), Positives = 88/190 (45%), Gaps = 15/190 (7%)
Query: 413 RYDNQISV--FGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDS 470
RY Q+ + F +E Q + V ++G+G +G ALL LA+ G++ + D+D
Sbjct: 71 RYSRQLLLPSFAVEGQSNLLKSSVLVIGAGGLGSP-----ALLYLAACGVGQLGIIDHDV 125
Query: 471 IEKSNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFW 530
+E +N++RQ + +G K + AA A ++N + K++ ++ + T N
Sbjct: 126 VELNNMHRQIIHTEAFIGHPKVKSAAAACRSINSTI--KVDEYVEAL--RTSNALE--IL 179
Query: 531 NQLDFVTNALDNVDARTYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSS--SRD 588
+Q D + +A DN +R + CV KPL+ LG +G V N Y
Sbjct: 180 SQYDIIVDATDNPPSRYMISDCCVLLGKPLVSGAALGMEGQLTVYNHNGGPCYRCLFPTP 239
Query: 589 PPEKSIPLCT 598
PP + C+
Sbjct: 240 PPTSACQRCS 249
>YHR111w [H] KOG2017 Molybdopterin synthase sulfurylase
Length = 440
Score = 65.5 bits (158), Expect = 4e-10
Identities = 59/212 (27%), Positives = 93/212 (43%), Gaps = 17/212 (8%)
Query: 392 ESLPDSEDFPRNADTTKPINSRYDNQISVF---GLEFQKRIANLKVFLVGSGAIGCEMLK 448
E L ED R+ + RY Q+ V G+ Q ++ N KV +VG+G +GC
Sbjct: 25 EQLAKREDSSRDYPLSLEEYQRYGRQMIVEETGGVAGQVKLKNTKVLVVGAGGLGCP--- 81
Query: 449 NWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKG 508
AL LA G+I + DND +E SNL+RQ L VG K E A ++ +NP +
Sbjct: 82 --ALPYLAGAGVGQIGIVDNDVVETSNLHRQVLHDSSRVGMLKCESARQYITKLNPHINV 139
Query: 509 KIEPKIDKVGAETENIFNDAFWNQLDFVTNALDNVDARTYVDRRCVFYKKPLLESGTLGT 568
P V + N F+ + +++ + D+ R V V ++ + LGT
Sbjct: 140 VTYP----VRLNSSNAFD--IFKGYNYILDCTDSPLTRYLVSDVAVNLGITVVSASGLGT 193
Query: 569 KGNTQVV-IPNLTESYSS--SRDPPEKSIPLC 597
+G ++ N+ Y PP ++ C
Sbjct: 194 EGQLTILNFNNIGPCYRCFYPTPPPPNAVTSC 225
>At1g05350 [H] KOG2336 Molybdopterin biosynthesis-related protein
Length = 445
Score = 63.9 bits (154), Expect = 1e-09
Identities = 50/176 (28%), Positives = 89/176 (50%), Gaps = 20/176 (11%)
Query: 427 KRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKD 486
+RI V +VG G +G + G+ G++++ D D++E +N+NR F FRP
Sbjct: 78 ERIREFSVAIVGIGGVGSVAAEMLTRCGI-----GRLLLYDYDTVELANMNRLF-FRPDQ 131
Query: 487 VGRNKSEVAADAVSAMNPD-LKGKIEPKIDKV-GAE--TENIFNDAF------WNQLDFV 536
VG K++ A ++ +NPD + I V G E T ++ N +F + +D V
Sbjct: 132 VGMTKTDAAVQTLAEINPDVVLESFTMNITTVQGFETFTSSLTNKSFCPSKEGGSGVDLV 191
Query: 537 TNALDNVDARTYVDRRCVFYKKPLLESGTL--GTKGNTQVVIPNLTESYSSSRDPP 590
+ +DN +AR V++ C ++ +ESG G+ Q+++P T ++ + PP
Sbjct: 192 LSCVDNYEARMAVNQACNELRQTWMESGVSEDAVSGHIQLLVPGETACFACA--PP 245
>7297432 [H] KOG2017 Molybdopterin synthase sulfurylase
Length = 453
Score = 63.2 bits (152), Expect = 2e-09
Identities = 49/181 (27%), Positives = 78/181 (43%), Gaps = 13/181 (7%)
Query: 396 DSEDFPRNADTTKPINSRYDNQISV--FGLEFQKRIANLKVFLVGSGAIGCEMLKNWALL 453
+S D + T +RY Q+ + FG++ Q ++ N V +VG G +GC + A
Sbjct: 54 ESPDVAVHTKLTNDDIARYSRQLILPDFGVQGQLKLKNSSVLIVGLGGLGCPAAQYLAAA 113
Query: 454 GLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKGKIEPK 513
G G + + D D +E+SN +RQ L G +K+E A A+ +NP + + +
Sbjct: 114 GC-----GHLGLVDYDEVERSNFHRQILHSEDRCGMSKAESARIALLELNPHCEIQCHSR 168
Query: 514 IDKVGAETENIFNDAFWNQLDFVTNALDNVDARTYVDRRCVFYKKPLLESGTLGTKGNTQ 573
+ N + D V + DNV R + CV KPL+ L G
Sbjct: 169 M----LYPHNAMH--IIRGYDVVLDCTDNVPTRYLLSDACVMLSKPLVSGSALKMDGQLT 222
Query: 574 V 574
V
Sbjct: 223 V 223
Score = 52.8 bits (125), Expect = 3e-06
Identities = 33/97 (34%), Positives = 52/97 (53%), Gaps = 2/97 (2%)
Query: 12 DESLYSRQLYV--LGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVA 69
D + YSRQL + G + LK+++S+VLI+GL GLG A+ + AG L L D V
Sbjct: 68 DIARYSRQLILPDFGVQGQLKLKNSSVLIVGLGGLGCPAAQYLAAAGCGHLGLVDYDEVE 127
Query: 70 LQDLSTQFFLSEQDIGQARDKVSQAKLAELNSYVPVK 106
+ Q SE G ++ + ++ L ELN + ++
Sbjct: 128 RSNFHRQILHSEDRCGMSKAESARIALLELNPHCEIQ 164
>SPAC2G11.10c [H] KOG2017 Molybdopterin synthase sulfurylase
Length = 401
Score = 59.7 bits (143), Expect = 2e-08
Identities = 44/161 (27%), Positives = 75/161 (46%), Gaps = 13/161 (8%)
Query: 412 SRYDNQ--ISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDND 469
SRY Q +S GL Q + V ++G+G +GC ++ G+ G + + D D
Sbjct: 22 SRYGRQMLLSEIGLPGQLSLKRSSVLVIGAGGLGCPAMQYLVAAGI-----GTLGIMDGD 76
Query: 470 SIEKSNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAF 529
++KSNL+RQ + G +K+ A + +NP++ I ++ A N+F +
Sbjct: 77 VVDKSNLHRQIIHSTSKQGMHKAISAKQFLEDLNPNV--IINTYLE--FASASNLF--SI 130
Query: 530 WNQLDFVTNALDNVDARTYVDRRCVFYKKPLLESGTLGTKG 570
Q D V + DN R + CV +PL+ + L +G
Sbjct: 131 IEQYDVVLDCTDNQYTRYLISDTCVLLGRPLVSASALKLEG 171
>CE13096 [H] KOG2336 Molybdopterin biosynthesis-related protein
Length = 419
Score = 58.9 bits (141), Expect = 4e-08
Identities = 47/170 (27%), Positives = 80/170 (46%), Gaps = 23/170 (13%)
Query: 427 KRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKD 486
+RI V +VG G +G + + G+ GK+I+ D D +E +N+NR F ++P
Sbjct: 80 ERIREKTVAVVGVGGVGSVVAEMLTRCGI-----GKLILFDYDKVEIANMNRLF-YQPNQ 133
Query: 487 VGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWN----------QLDFV 536
G +K E A D + +NPD ++ ++ T + F D F N ++D V
Sbjct: 134 AGLSKVEAARDTLIHVNPD----VQIEVHNFNITTMDNF-DTFVNRIRKGSLTDGKIDLV 188
Query: 537 TNALDNVDARTYVDRRCVFYKKPLLESGTL--GTKGNTQVVIPNLTESYS 584
+ +DN +AR V+ C + +ESG G+ Q + P T ++
Sbjct: 189 LSCVDNFEARMAVNMACNEENQIWMESGVSENAVSGHIQYIEPGKTACFA 238
>At5g37530 [O] KOG2018 Predicted dinucleotide-utilizing enzyme involved in
molybdopterin and thiamine biosynthesis
Length = 414
Score = 57.4 bits (137), Expect = 1e-07
Identities = 51/204 (25%), Positives = 96/204 (47%), Gaps = 14/204 (6%)
Query: 392 ESLPDSEDFPRNADTTKPINSRYDNQISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWA 451
E+ PD+ ++ + ++ I FGLE Q ++ V ++G G +G A
Sbjct: 11 ETRPDTVANGQDLLKDEIVSEHLTRNIQFFGLESQHKVTGSYVVVIGLGGVGSHA----A 66
Query: 452 LLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKGKIE 511
+ L SG GK+++ D D + S+LNR + DVG K+ S++ P+ IE
Sbjct: 67 SMLLRSGV-GKLLLVDFDQVSLSSLNRHAVATRADVGIPKAMCLKKHFSSIFPEC--HIE 123
Query: 512 PKIDKVGAETENIFNDAFWNQLDFVTNALDNVDARTYVDRRCVFYKKPLLESGTLGTKGN 571
K+ + +E + + DFV + +DN+D + + CV +L + G + +
Sbjct: 124 AKVMLYDSSSE---EEILSGKPDFVLDCIDNIDTKVGLLAACVKRGLKVLSATGAGARAD 180
Query: 572 -TQVVIPNLTESYSSSRDPPEKSI 594
T++ + ++ E S+ DP +S+
Sbjct: 181 PTRIRVADIRE---STIDPLSRSV 201
>SPAC323.06c [O] KOG2016 NEDD8-activating complex APP-BP1/UBA5 component
Length = 500
Score = 56.6 bits (135), Expect = 2e-07
Identities = 44/172 (25%), Positives = 83/172 (47%), Gaps = 12/172 (6%)
Query: 16 YSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVALQDLST 75
Y RQ+ + E ++ S+V ++ +G E KN++L G+ S + D ++V
Sbjct: 10 YDRQVRLWKAEGQNAIEKSHVCLLYANTVGCEALKNLILPGIGSFAVVDDTSVDFSMDGM 69
Query: 76 QFFLSEQDIGQARDKVSQAKLAELNSYVPVKVLEGL------EDVSQLSEFQVVVVTDTI 129
FF+ G++R + + + L +LN V ++ LE +++ S+F VV+ +
Sbjct: 70 NFFIQYDQEGKSRARCTASLLQQLNPNVEMEYLEMSPEALIDKNIEYFSKFSVVL---SS 126
Query: 130 SLEEK--VKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDTTGEEPK 179
+L+EK +L EY SH I + + G G + + E+T + E P+
Sbjct: 127 NLKEKPLFRLEEYLRSHKIPLLHFNSVGFAGILRIST-HEYTTTQSQPELPQ 177
>SPAC1A6.10 [O] KOG2018 Predicted dinucleotide-utilizing enzyme involved in
molybdopterin and thiamine biosynthesis
Length = 485
Score = 56.6 bits (135), Expect = 2e-07
Identities = 56/221 (25%), Positives = 94/221 (42%), Gaps = 29/221 (13%)
Query: 374 ASSGKFTPIKQYMYFDSIESLPDSEDFPRNADTTKPINSRYDNQISVFGLEFQKRIANLK 433
+SSG PI+ Y + E + + N I + + FG + +R+ N
Sbjct: 76 SSSG--VPIEIYDAGEEDEGISKGVPYDENL-----IREQLARNYAFFGEDGMERLRNSF 128
Query: 434 VFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKDVGRNKSE 493
V +VG G +G +W + LA KI + D D + S+LNR + +DVG K+
Sbjct: 129 VIVVGCGGVG-----SWVINMLARSGVQKIRIVDFDQVSLSSLNRHSIATLQDVGTPKTL 183
Query: 494 VAADAVSAMNPDLKGKIEPKIDKVGAETENIFN-----DAFWNQLDFVTNALDNVDARTY 548
A+ P + ++D A +FN D DFV +A+DN+ +
Sbjct: 184 AIKKAIKKFAPWI------EVDARNA----LFNPDSADDLLSGNPDFVIDAIDNIQTKVD 233
Query: 549 VDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDP 589
+ C +K P++ S K + V N+ + ++S DP
Sbjct: 234 LLSYCYNHKLPVIASTGSACKSDPTRV--NIADISATSEDP 272
>Hs13376212 [H] KOG2336 Molybdopterin biosynthesis-related protein
Length = 404
Score = 55.8 bits (133), Expect = 3e-07
Identities = 46/173 (26%), Positives = 79/173 (45%), Gaps = 18/173 (10%)
Query: 427 KRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKD 486
++I V +VG G +G + G+ GK+++ D D +E +N+NR F F+P
Sbjct: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGI-----GKLLLFDYDKVELANMNRLF-FQPHQ 122
Query: 487 VGRNKSEVAADAVSAMNPDLKGKIEPKIDKVGAETENIFNDAFWN-------QLDFVTNA 539
G +K + A + +NPD+ ++ + E F D N +D V +
Sbjct: 123 AGLSKVQAAEHTLRNINPDVLFEVH-NYNITTVENFQHFMDRISNGGLEEGKPVDLVLSC 181
Query: 540 LDNVDARTYVDRRCVFYKKPLLESGTL--GTKGNTQVVIPNLTESYSSSRDPP 590
+DN +AR ++ C + +ESG G+ Q++IP ES + PP
Sbjct: 182 VDNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIPG--ESACFACAPP 232
>Hs7657339 [H] KOG2017 Molybdopterin synthase sulfurylase
Length = 460
Score = 54.7 bits (130), Expect = 7e-07
Identities = 50/185 (27%), Positives = 80/185 (43%), Gaps = 13/185 (7%)
Query: 392 ESLPDSEDFPRNADTTKPINSRYDNQISV--FGLEFQKRIANLKVFLVGSGAIGCEMLKN 449
E L P A ++ RY Q+ + G+ Q R+ V +VG G +GC + +
Sbjct: 41 ERLVPVSPLPPKAALSRDEILRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQY 100
Query: 450 WALLGLASGPEGKIIVTDNDSIEKSNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKGK 509
A G+ G++ + D D +E SNL RQ L G+ K+ AA ++ +N ++
Sbjct: 101 LAAAGV-----GRLGLVDYDVVEMSNLARQVLHGEALAGQAKAFSAAASLRRLNSAVEC- 154
Query: 510 IEPKIDKVGAETENIFNDAFWNQLDFVTNALDNVDARTYVDRRCVFYKKPLLESGTLGTK 569
+ A T D + D V + DNV R V+ CV +PL+ + L +
Sbjct: 155 ----VPYTQALTPATALDLV-RRYDVVADCSDNVPTRYLVNDACVLAGRPLVSASALRFE 209
Query: 570 GNTQV 574
G V
Sbjct: 210 GQITV 214
Score = 51.6 bits (122), Expect = 6e-06
Identities = 38/95 (40%), Positives = 51/95 (53%), Gaps = 3/95 (3%)
Query: 12 DESL-YSRQLYV--LGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAV 68
DE L YSRQL + LG L++ + VLI+G GLG +A+ + AGV L L D V
Sbjct: 58 DEILRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDYDVV 117
Query: 69 ALQDLSTQFFLSEQDIGQARDKVSQAKLAELNSYV 103
+ +L+ Q E GQA+ + A L LNS V
Sbjct: 118 EMSNLARQVLHGEALAGQAKAFSAAASLRRLNSAV 152
>7294767 [O] KOG2016 NEDD8-activating complex APP-BP1/UBA5 component
Length = 524
Score = 53.5 bits (127), Expect = 2e-06
Identities = 55/268 (20%), Positives = 103/268 (37%), Gaps = 14/268 (5%)
Query: 411 NSRYDNQISVFGLEFQKRIANLKVFLVGSGAIGCEMLKNWALLGLASGPEGKIIVTDNDS 470
+ +YD QI ++G Q + V LV A+GCE K L G+ G V D +
Sbjct: 15 SKKYDRQIRLWGEHGQTLLEAATVCLVNVTAVGCETAKGLVLPGI-----GGFTVADGST 69
Query: 471 IEKSNLNRQFLFRPKDVGRNKSEVAADAVSAMNPDLKGK-IEPKIDKVGAETENIFNDAF 529
+++ +L F +G++K+ + +NPD+ G ++ D + A N F
Sbjct: 70 VKEEDLGNNFFLDSSYLGKSKALACMQLLQELNPDVNGDYVDESADFLLANRPN-----F 124
Query: 530 WNQLDFVTNALDNVDARTYVDRRCVFYKKPLLESGTLGTKGNTQVVIPNLTESYSSSRDP 589
++ D V + N + R PL+ +LG G ++ + E P
Sbjct: 125 FDSFDLVIASNLNEQTLLLLAERLWELNVPLIYCRSLGMLGTIRL---QIREHCIVEAHP 181
Query: 590 PEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFSDAAENVNLYLTQPNFVEQTLKQAPDAK 649
+ L F +H + + + +N++ Q QT + +
Sbjct: 182 DNRQFDLRLEHPFDALREHLDGTEVTSKVPWLLVLHKYLNVWQKQQADGTQTPRNYKEKN 241
Query: 650 GILESISDCLNNRPYNFEDCVKWARLEF 677
+ E+I + + N+E+ +K F
Sbjct: 242 QLKETIREEMKADEENYEEAIKAVNTAF 269
Score = 52.4 bits (124), Expect = 4e-06
Identities = 26/85 (30%), Positives = 44/85 (51%)
Query: 16 YSRQLYVLGKEAMLKMQHSNVLIIGLKGLGVEIAKNVVLAGVKSLTLYDPSAVALQDLST 75
Y RQ+ + G+ ++ + V ++ + +G E AK +VL G+ T+ D S V +DL
Sbjct: 18 YDRQIRLWGEHGQTLLEAATVCLVNVTAVGCETAKGLVLPGIGGFTVADGSTVKEEDLGN 77
Query: 76 QFFLSEQDIGQARDKVSQAKLAELN 100
FFL +G+++ L ELN
Sbjct: 78 NFFLDSSYLGKSKALACMQLLQELN 102
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.136 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,523,580
Number of Sequences: 60738
Number of extensions: 2786360
Number of successful extensions: 7001
Number of sequences better than 1.0e-05: 51
Number of HSP's better than 0.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 6685
Number of HSP's gapped (non-prelim): 136
length of query: 1019
length of database: 30,389,216
effective HSP length: 116
effective length of query: 903
effective length of database: 23,343,608
effective search space: 21079278024
effective search space used: 21079278024
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)