ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3756 good R KOG1577 General function prediction only Aldo/keto reductase family proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3756 1292883 1291954 -310
(310 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR120w [R] KOG1577 Aldo/keto reductase family proteins 394 e-110
YDR368w [R] KOG1577 Aldo/keto reductase family proteins 392 e-109
SPAC26F1.07 [R] KOG1577 Aldo/keto reductase family proteins 222 5e-58
Hs5174391 [R] KOG1577 Aldo/keto reductase family proteins 217 2e-56
ECU01g0970 [R] KOG1577 Aldo/keto reductase family proteins 213 2e-55
At2g37770 [R] KOG1577 Aldo/keto reductase family proteins 212 6e-55
SPBC8E4.04 [R] KOG1577 Aldo/keto reductase family proteins 211 1e-54
At2g37790 [R] KOG1577 Aldo/keto reductase family proteins 210 2e-54
At3g53880 [R] KOG1577 Aldo/keto reductase family proteins 209 3e-54
Hs4502049 [R] KOG1577 Aldo/keto reductase family proteins 209 4e-54
7294702 [R] KOG1577 Aldo/keto reductase family proteins 208 9e-54
At5g01670 [R] KOG1577 Aldo/keto reductase family proteins 202 7e-52
CE21733 [R] KOG1577 Aldo/keto reductase family proteins 201 1e-51
7298972 [R] KOG1577 Aldo/keto reductase family proteins 201 1e-51
7292407 [R] KOG1577 Aldo/keto reductase family proteins 200 2e-51
CE24243 [R] KOG1577 Aldo/keto reductase family proteins 199 4e-51
Hs20127592 [R] KOG1577 Aldo/keto reductase family proteins 198 7e-51
Hs11386205 [R] KOG1577 Aldo/keto reductase family proteins 197 2e-50
Hs4503285 [R] KOG1577 Aldo/keto reductase family proteins 196 3e-50
At2g37760 [R] KOG1577 Aldo/keto reductase family proteins 196 4e-50
Hs5453543 [R] KOG1577 Aldo/keto reductase family proteins 195 8e-50
Hs20127601 [R] KOG1577 Aldo/keto reductase family proteins 194 2e-49
At5g62420 [R] KOG1577 Aldo/keto reductase family proteins 190 3e-48
7294701 [R] KOG1577 Aldo/keto reductase family proteins 190 3e-48
YBR149w [R] KOG1577 Aldo/keto reductase family proteins 186 5e-47
Hs13899261 [R] KOG1577 Aldo/keto reductase family proteins 186 5e-47
At2g21260 [R] KOG1577 Aldo/keto reductase family proteins 185 8e-47
At2g21250 [R] KOG1577 Aldo/keto reductase family proteins 182 4e-46
7292408 [R] KOG1577 Aldo/keto reductase family proteins 182 7e-46
7302301 [R] KOG1577 Aldo/keto reductase family proteins 181 2e-45
CE10936 [R] KOG1577 Aldo/keto reductase family proteins 176 5e-44
Hs5174695 [R] KOG1577 Aldo/keto reductase family proteins 175 7e-44
CE06776 [R] KOG1577 Aldo/keto reductase family proteins 175 7e-44
CE17230 [R] KOG1577 Aldo/keto reductase family proteins 174 2e-43
7294572 [R] KOG1577 Aldo/keto reductase family proteins 167 1e-41
SPAC2F3.05c [R] KOG1577 Aldo/keto reductase family proteins 167 2e-41
SPAP32A8.02 [R] KOG1577 Aldo/keto reductase family proteins 164 2e-40
CE10934 [R] KOG1577 Aldo/keto reductase family proteins 164 2e-40
Hs17450865 [R] KOG1577 Aldo/keto reductase family proteins 162 8e-40
CE01200 [R] KOG1577 Aldo/keto reductase family proteins 162 8e-40
YJR096w [R] KOG1577 Aldo/keto reductase family proteins 161 1e-39
CE27788 [R] KOG1577 Aldo/keto reductase family proteins 159 4e-39
Hs17465400 [R] KOG1577 Aldo/keto reductase family proteins 157 2e-38
CE24244 [R] KOG1577 Aldo/keto reductase family proteins 155 9e-38
7294573 [R] KOG1577 Aldo/keto reductase family proteins 151 1e-36
At1g59950 [R] KOG1577 Aldo/keto reductase family proteins 150 2e-36
YHR104w [R] KOG1577 Aldo/keto reductase family proteins 148 1e-35
At1g59960 [R] KOG1577 Aldo/keto reductase family proteins 147 2e-35
CE06751 [R] KOG1577 Aldo/keto reductase family proteins 147 2e-35
Hs22054710 [R] KOG1577 Aldo/keto reductase family proteins 146 3e-35
SPAC19G12.09 [R] KOG1577 Aldo/keto reductase family proteins 144 1e-34
Hs20545142 [R] KOG1577 Aldo/keto reductase family proteins 138 9e-33
YDL124w [R] KOG1577 Aldo/keto reductase family proteins 134 2e-31
CE15543 [R] KOG1577 Aldo/keto reductase family proteins 134 2e-31
Hs20470761 [R] KOG1577 Aldo/keto reductase family proteins 133 3e-31
CE06112 [R] KOG1577 Aldo/keto reductase family proteins 122 9e-28
Hs20537171 [R] KOG1577 Aldo/keto reductase family proteins 117 3e-26
SPBC28F2.05c [R] KOG1577 Aldo/keto reductase family proteins 95 1e-19
Hs16156291 [R] KOG1577 Aldo/keto reductase family proteins 92 1e-18
CE06775 [R] KOG1577 Aldo/keto reductase family proteins 72 8e-13
At1g60680 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 69 1e-11
Hs22058392 [R] KOG1577 Aldo/keto reductase family proteins 68 2e-11
Hs22060498 [R] KOG1577 Aldo/keto reductase family proteins 67 3e-11
SPAC1F7.12 [C] KOG1575 Voltage-gated shaker-like K+ channel subu... 67 3e-11
At1g60750 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 66 7e-11
SPCC965.06 [C] KOG1575 Voltage-gated shaker-like K+ channel subu... 64 2e-10
At1g60710 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 64 3e-10
At1g60690 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 62 8e-10
At4g33670 [C] KOG1576 Predicted oxidoreductase 61 2e-09
7299543 [C] KOG1576 Predicted oxidoreductase 57 3e-08
Hs17491434 [R] KOG1577 Aldo/keto reductase family proteins 56 6e-08
At1g60730 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 56 8e-08
At5g53580 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 54 2e-07
At1g10810 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 53 5e-07
At1g04420 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 52 1e-06
Hs4504825 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 49 9e-06
>YOR120w [R] KOG1577 Aldo/keto reductase family proteins
Length = 312
Score = 394 bits (1012), Expect = e-110
Identities = 189/301 (62%), Positives = 235/301 (77%)
Query: 10 LKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIRDSGV 69
L LNTGA IP +GLGTW+S E DAY AV++AL++GYRHIDTAAIY NE+ VG+ I+DSGV
Sbjct: 12 LSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIKDSGV 71
Query: 70 PREEIFVTTKLWGTQQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNYLTFP 129
PREEIFVTTKLW TQ +PE ALD SL+RLGLDYVDLYL+HWP L+ + I + + L+ P
Sbjct: 72 PREEIFVTTKLWCTQHHEPEVALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVP 131
Query: 130 RTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIVPAA 189
DG +DI WNFIKTWE MQ LPK+GKTKA+GVSNFSI N++ LLA+ + + PAA
Sbjct: 132 TKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAA 191
Query: 190 NQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSSTILTDPTIEGIASKYNAEPANILI 249
NQ+EIHP LPQ ELI++CKSKGI++EAYSPLGS+ + +L +P I IA K N +P +++I
Sbjct: 192 NQVEIHPLLPQDELINFCKSKGIVVEAYSPLGSTDAPLLKEPVILEIAKKNNVQPGHVVI 251
Query: 250 SWGASRGYVVLPKSVNPQRIKTNLKLLDLSTEDLEKINKLTESVGAKRYVAPDFSPFAIF 309
SW RGYVVLPKSVNP RIKTN K+ LSTED E IN +++ G KR V P++SPF +F
Sbjct: 252 SWHVQRGYVVLPKSVNPDRIKTNRKIFTLSTEDFEAINNISKEKGEKRVVHPNWSPFEVF 311
Query: 310 E 310
+
Sbjct: 312 K 312
>YDR368w [R] KOG1577 Aldo/keto reductase family proteins
Length = 312
Score = 392 bits (1006), Expect = e-109
Identities = 187/306 (61%), Positives = 235/306 (76%)
Query: 5 NESPSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGI 64
N S +LKLNTGASIPV+G GTW+S + + Y++V++AL+ GYRHID AAIY NEE VG+ I
Sbjct: 7 NSSATLKLNTGASIPVLGFGTWRSVDNNGYHSVIAALKAGYRHIDAAAIYLNEEEVGRAI 66
Query: 65 RDSGVPREEIFVTTKLWGTQQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGN 124
+DSGVPREEIF+TTKLWGT+QRDPEAAL+ SL+RLGLDYVDLYL+HWPVPL +TDGN
Sbjct: 67 KDSGVPREEIFITTKLWGTEQRDPEAALNKSLKRLGLDYVDLYLMHWPVPLKTDRVTDGN 126
Query: 125 YLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDF 184
L P DG +DID +EWNFIKTWE MQ LPK+GKTKA+GVSNFSI NI+ LL + +
Sbjct: 127 VLCIPTLEDGTVDIDTKEWNFIKTWELMQELPKTGKTKAVGVSNFSINNIKELLESPNNK 186
Query: 185 IVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSSTILTDPTIEGIASKYNAEP 244
+VPA NQIEIHP LPQ ELI +CK KGI++EAYSP GS+++ +L + I +A K+ EP
Sbjct: 187 VVPATNQIEIHPLLPQDELIAFCKEKGIVVEAYSPFGSANAPLLKEQAIIDMAKKHGVEP 246
Query: 245 ANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLSTEDLEKINKLTESVGAKRYVAPDFS 304
A ++ISW RGYVVL KSVNP+RI +N K+ L +D + I+ L++ G KR V +
Sbjct: 247 AQLIISWSIQRGYVVLAKSVNPERIVSNFKIFTLPEDDFKTISNLSKVHGTKRVVDMKWG 306
Query: 305 PFAIFE 310
F IF+
Sbjct: 307 SFPIFQ 312
>SPAC26F1.07 [R] KOG1577 Aldo/keto reductase family proteins
Length = 321
Score = 222 bits (566), Expect = 5e-58
Identities = 130/291 (44%), Positives = 180/291 (61%), Gaps = 25/291 (8%)
Query: 12 LNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIRDSGVPR 71
L G+ IP +GLGTW+S NAV +ALQ GYRHID AAIYGNE+ VG GI++SGVPR
Sbjct: 18 LADGSKIPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIKESGVPR 77
Query: 72 EEIFVTTKLWGTQQRDPEA---ALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNYLTF 128
++I+VT+KLW PEA AL+ +L+ L LDY+D YLIHWPV F
Sbjct: 78 KDIWVTSKLW-CNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGED------KF 130
Query: 129 PRTADGKIDIDIEEWNFI-KTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIVP 187
P+ DG + I E N I +TW+ M+ L ++GK + IG+SNF+ N+E +L + P
Sbjct: 131 PKDKDGNL---IYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAK--VKP 185
Query: 188 AANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSS-------TILTDPTIEGIASK- 239
A +Q+E+HP LPQTE ++ K GI + AYSP G+ ++ ++ TI+ IA
Sbjct: 186 AVHQMELHPFLPQTEFVEKHKKLGIHVTAYSPFGNQNTIYESKIPKLIEHETIQKIAKSK 245
Query: 240 -YNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLSTEDLEKINKL 289
A I +SW +RG V+PKSVN QRIK+N K + L+ ED+++IN +
Sbjct: 246 GEGVTGATIAVSWAITRGTSVIPKSVNEQRIKSNFKYIPLTKEDMDEINSI 296
>Hs5174391 [R] KOG1577 Aldo/keto reductase family proteins
Length = 325
Score = 217 bits (553), Expect = 2e-56
Identities = 122/307 (39%), Positives = 179/307 (57%), Gaps = 30/307 (9%)
Query: 12 LNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIRD----- 66
L+TG +P++GLGTWKS AV AL GYRHID AAIYGNE +G+ +++
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 67 SGVPREEIFVTTKLWGTQQ--RDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGN 124
VPREE+FVT+KLW T+ D E AL +L L L+Y+DLYL+HWP
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD----- 122
Query: 125 YLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDF 184
FP+ ADG I D ++ +TW+ ++ L G +A+G+SNF+ + I+ +L+
Sbjct: 123 -NPFPKNADGTICYD--STHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS-- 177
Query: 185 IVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSS--------SSTILTDPTIEGI 236
+ PA Q+E HP L Q ELI +C+++G+ + AYSPLGSS +L +P + +
Sbjct: 178 VRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLAL 237
Query: 237 ASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKINKLTESVG 294
A KY PA IL+ W R + +PKS+ P RI N+K+ D S E+++++N L ++
Sbjct: 238 AEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKN-- 295
Query: 295 AKRYVAP 301
RY+ P
Sbjct: 296 -WRYIVP 301
>ECU01g0970 [R] KOG1577 Aldo/keto reductase family proteins
Length = 301
Score = 213 bits (543), Expect = 2e-55
Identities = 129/308 (41%), Positives = 180/308 (57%), Gaps = 30/308 (9%)
Query: 11 KLNTGASIPVVGLGTWKSPEEDAYN-AVVSALQNGYRHIDTAAIYGNEEAVG---KGIRD 66
KLN G IP VGLGTW +E A+ +AL GYRHIDTA IYGNE+ +G K + D
Sbjct: 7 KLNNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFD 66
Query: 67 SGV-PREEIFVTTKLWGTQQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNY 125
GV R+++F+T+KLW T PE L SL L +DYVDLYLIHWPV
Sbjct: 67 EGVVQRKDLFITSKLWNTFHGCPEDGLRRSLNDLQMDYVDLYLIHWPV------------ 114
Query: 126 LTFPRTADGKID-----IDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAA 180
TF DG ++ ++ +++ + W+KM+ L G K+IG+SNF N E +L
Sbjct: 115 -TFDPAPDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGT 173
Query: 181 NPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGS---SSSTILTDPTIEGIA 237
I PAA QIE+HP L Q EL+++ KSKGI + +YS LGS SS+ + D TI+ IA
Sbjct: 174 CR--ICPAAIQIELHPYLNQKELVEFMKSKGIQVISYSSLGSAPGSSAKVRDDKTIKAIA 231
Query: 238 SKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLSTEDLEKINKLTESVGAKR 297
KY P+ I++S+ ++G V+PKS + + ++ N+ L +LS ED+ I+ L + G +
Sbjct: 232 KKYGCAPSQIILSYITAQGICVIPKSRSKEHLRENIDLKELSREDISAIDAL--NTGHRY 289
Query: 298 YVAPDFSP 305
P F P
Sbjct: 290 VDPPGFGP 297
>At2g37770 [R] KOG1577 Aldo/keto reductase family proteins
Length = 290
Score = 212 bits (539), Expect = 6e-55
Identities = 123/290 (42%), Positives = 166/290 (56%), Gaps = 26/290 (8%)
Query: 4 SNESPSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVG-- 61
+N KLNTGA P VGLGTW++ +AV +A++ GYRHID A IYGNE+ +G
Sbjct: 2 ANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAV 61
Query: 62 --KGIRDSGVPREEIFVTTKLWGTQQ--RDPEAALDLSLQRLGLDYVDLYLIHWPVPLNA 117
K D V RE++F+T+KLW T +D AL+ +L+ L L+YVDLYLIHWP +
Sbjct: 62 LKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK 121
Query: 118 SSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEAL 177
S+ + + +DI TW+ M+ L SGK +AIGVSNFS K + L
Sbjct: 122 GSV--------GIKPENLLPVDIP-----STWKAMEALYDSGKARAIGVSNFSTKKLADL 168
Query: 178 LAANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSST-----ILTDPT 232
L + PA NQ+E HP QT+L ++CKSKG+ + AYSPLGS +T +L +P
Sbjct: 169 LELAR--VPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPI 226
Query: 233 IEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLSTED 282
+ +A K PA + + WG G+ VLPKS N RIK N + D S D
Sbjct: 227 LNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPD 276
>SPBC8E4.04 [R] KOG1577 Aldo/keto reductase family proteins
Length = 325
Score = 211 bits (536), Expect = 1e-54
Identities = 127/312 (40%), Positives = 182/312 (57%), Gaps = 30/312 (9%)
Query: 12 LNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIRDSGVPR 71
L G IP +GLGTW+S +++ NAV +AL+ GYRHIDTA IYGNE+ +G+GIR+SGVPR
Sbjct: 17 LPNGDKIPSIGLGTWRSGKDETKNAVCAALKAGYRHIDTAHIYGNEKEIGEGIRESGVPR 76
Query: 72 EEIFVTTKLWGTQQRD--PEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNYLTFP 129
+I+VT+KLW R AL+ +LQ L L+Y+D YLIHWP L + P
Sbjct: 77 TDIWVTSKLWCNAHRAGLVPLALEKTLQDLNLEYIDAYLIHWPFALLSGP------EELP 130
Query: 130 RTADGKI---DIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIV 186
R G++ D+ IEE TW+ M+ L ++GK + IG+SNF+ + ++ +L +
Sbjct: 131 RNEKGELIYEDVPIEE-----TWQAMEELLETGKVRYIGISNFNNEYLDRVLKIAK--VK 183
Query: 187 PAANQIEIHPQLPQTELIDYCKSKGILIEAYSPL-------GSSSSTILTDPTIEGIASK 239
P +Q+E+HP LPQTE ++ K I + AYSPL S S ++ T+ IA+
Sbjct: 184 PTIHQMELHPYLPQTEYLEKHKKLQIHVSAYSPLANQNDAYNSDISKLIEHKTLVDIANA 243
Query: 240 --YNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLSTEDLEKINKLTESVGAKR 297
PANI ISW RG VLPKSVN RI +N + L+ +++E IN + +R
Sbjct: 244 RGEGITPANIAISWAVKRGTSVLPKSVNESRIVSNFLYIPLTDKEMEAINNIGV---VRR 300
Query: 298 YVAPDFSPFAIF 309
+ F+P +F
Sbjct: 301 FSHGKFAPKPMF 312
>At2g37790 [R] KOG1577 Aldo/keto reductase family proteins
Length = 350
Score = 210 bits (535), Expect = 2e-54
Identities = 129/293 (44%), Positives = 170/293 (57%), Gaps = 29/293 (9%)
Query: 11 KLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVG---KGIRDS 67
+LNTGA IP VGLGTW++ NAV +A++ GYRHID A IYGNE+ +G K + D
Sbjct: 9 ELNTGAKIPSVGLGTWQADPGLVGNAVDAAVKIGYRHIDCAQIYGNEKEIGLVLKKLFDG 68
Query: 68 G-VPREEIFVTTKLWGTQQRDPE---AALDLSLQRLGLDYVDLYLIHWPVPLNASSITDG 123
G V REE+F+T+KLW T DP+ AL+ +LQ L LDYVDLYLIHWPV L S
Sbjct: 69 GVVKREEMFITSKLWCT-YHDPQEVPEALNRTLQDLQLDYVDLYLIHWPVSLKKGS---- 123
Query: 124 NYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPD 183
G +I + TW+ M+ L SGK +AIGVSNFS K + LL
Sbjct: 124 ---------TGFKPENILPTDIPSTWKAMESLFDSGKARAIGVSNFSSKKLADLLVVAR- 173
Query: 184 FIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSST-----ILTDPTIEGIAS 238
+ PA NQ+E HP Q L D+CKSKG+ + YSPLGS +T +L +P + G+A
Sbjct: 174 -VPPAVNQVECHPSWQQNVLRDFCKSKGVHLSGYSPLGSPGTTWLTSDVLKNPILGGVAE 232
Query: 239 KYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLSTEDLEKINKLTE 291
K PA + + WG G VLPKS + RIK N + + S + + ++K +E
Sbjct: 233 KLGKTPAQVALRWGLQMGQSVLPKSTHEDRIKQNFDVFNWSIPE-DMLSKFSE 284
>At3g53880 [R] KOG1577 Aldo/keto reductase family proteins
Length = 315
Score = 209 bits (533), Expect = 3e-54
Identities = 129/322 (40%), Positives = 181/322 (56%), Gaps = 30/322 (9%)
Query: 4 SNESPSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKG 63
++E +LNTGA IP VGLGTW++ +AV +A++ GY+HID A+ YGNE +GK
Sbjct: 2 ADEIGFFQLNTGAKIPSVGLGTWQAAPGVVGDAVAAAVKIGYQHIDCASRYGNEIEIGKV 61
Query: 64 IR----DSGVPREEIFVTTKLWGTQQRDPEA--ALDLSLQRLGLDYVDLYLIHWPVPLNA 117
++ D V RE++F+T+K+W T P+ AL+ +LQ L LDYVDLYL+HWPV L
Sbjct: 62 LKKLFDDGVVKREKLFITSKIWLTDLDPPDVQDALNRTLQDLQLDYVDLYLMHWPVRLKK 121
Query: 118 SSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEAL 177
++ P IDI TW+ M+ L SGK +AIGVSNFS K + L
Sbjct: 122 GTVDFKPENIMP------IDIP-------STWKAMEALVDSGKARAIGVSNFSTKKLSDL 168
Query: 178 LAANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSST-----ILTDPT 232
+ A + PA NQ+E HP Q +L ++CKSKGI + YSPLGS +T +L P
Sbjct: 169 VEAAR--VPPAVNQVECHPSWQQHKLHEFCKSKGIHLSGYSPLGSPGTTWVKADVLKSPV 226
Query: 233 IEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLL--DLSTEDLEKINKLT 290
IE IA + PA + WG G+ +LPKS N RI+ N +L + E +K +K+
Sbjct: 227 IEMIAKEIGKSPAQTALRWGLQMGHSILPKSTNEGRIRENFDVLGWSIPKEMFDKFSKIE 286
Query: 291 ES--VGAKRYVAPDFSPFAIFE 310
++ V +V SP+ E
Sbjct: 287 QARLVQGTSFVHETLSPYKTLE 308
>Hs4502049 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 209 bits (532), Expect = 4e-54
Identities = 124/290 (42%), Positives = 162/290 (55%), Gaps = 24/290 (8%)
Query: 10 LKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGI----R 65
L LN GA +P++GLGTWKSP AV A+ GYRHID A +Y NE VG I R
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 66 DSGVPREEIFVTTKLWGTQQRD--PEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDG 123
+ V REE+F+ +KLW T + A +L L LDY+DLYLIHWP
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK---- 120
Query: 124 NYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPD 183
FP G ++ + N + TW M+ L G KAIG+SNF+ +E +L
Sbjct: 121 --EFFPLDESG--NVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 184 FIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGS--------SSSTILTDPTIEG 235
PA NQIE HP L Q +LI YC+SKGI++ AYSPLGS ++L DP I+
Sbjct: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKA 236
Query: 236 IASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDL 283
IA+K+N A +LI + R VV+PKSV P+RI N K+ D LS++D+
Sbjct: 237 IAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDM 286
>7294702 [R] KOG1577 Aldo/keto reductase family proteins
Length = 302
Score = 208 bits (529), Expect = 9e-54
Identities = 125/295 (42%), Positives = 172/295 (57%), Gaps = 26/295 (8%)
Query: 8 PSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKG---- 63
P++K N G +P++GLGTW SP+ AV A+ GYRHID A +Y NE+ VG G
Sbjct: 4 PNVKFNNGKEVPIIGLGTWGSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAK 63
Query: 64 IRDSGVPREEIFVTTKLWGTQQRDP--EAALDLSLQRLGLDYVDLYLIHWPVPLNASSIT 121
I++ V RE++F+T+KLW T R ++AL+ +L L L Y+DLYLIHWP+
Sbjct: 64 IKEGVVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPM-----GYK 118
Query: 122 DGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAAN 181
+G L FP DGK +++ TW+ M+ L + G K+IGVSNF+ + IE +L
Sbjct: 119 EGCDL-FPTDKDGK--TLYSPVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVA 175
Query: 182 PDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGS--------SSSTILTDPTI 233
I P NQIE HP L Q +LID+CKSK I I AYSPLGS IL + I
Sbjct: 176 T--IPPVTNQIECHPYLTQKKLIDFCKSKDITITAYSPLGSPNRPWAKAGDPVILEEAKI 233
Query: 234 EGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKI 286
+ IA+K P ILI + R +V+PKSV RI++N ++ D L+ E++E I
Sbjct: 234 KEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDRIESNFQVFDFELTPEEIEII 288
>At5g01670 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 202 bits (513), Expect = 7e-52
Identities = 115/300 (38%), Positives = 173/300 (57%), Gaps = 27/300 (9%)
Query: 2 STSNESPSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVG 61
S S +L +G IP VGLGTW+S + A+ V + ++ GYRHIDTA YG++ VG
Sbjct: 8 SEGQNMESFRLLSGHKIPAVGLGTWRSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQREVG 67
Query: 62 KGIR---DSGVPREEIFVTTKLWGTQQRDPE---AALDLSLQRLGLDYVDLYLIHWPVPL 115
+GI+ +G+ R ++FVT+KLW T + PE AL +L+ L L+Y+DLYLIHWP+ L
Sbjct: 68 QGIKRAMHAGLERRDLFVTSKLWCT-ELSPERVRPALQNTLKELQLEYLDLYLIHWPIRL 126
Query: 116 NASSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIE 175
+ + P A +D D+E W +M++L K + IGV NF++ +
Sbjct: 127 REGA-------SKPPKAGDVLDFDME-----GVWREMENLSKDSLVRNIGVCNFTVTKLN 174
Query: 176 ALLAANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSS--TILTDPTI 233
LL ++PA Q+E+HP ++++CK I AYSPLGS ++ D T+
Sbjct: 175 KLLGFAE--LIPAVCQMEMHPGWRNDRILEFCKKNE--IHAYSPLGSQEGGRDLIHDQTV 230
Query: 234 EGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKINKLTE 291
+ IA K N P IL+ WG RG V+PKS+NP+RIK N+K+ D + +D + +N +T+
Sbjct: 231 DRIAKKLNKTPGQILVKWGLQRGTSVIPKSLNPERIKENIKVFDWVIPEQDFQALNSITD 290
>CE21733 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 201 bits (511), Expect = 1e-51
Identities = 119/304 (39%), Positives = 177/304 (58%), Gaps = 33/304 (10%)
Query: 9 SLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVG---KGIR 65
SLKLN+G SIP +GLGTW+S + A+ +A+ GYRHID A +Y N++ VG K I
Sbjct: 4 SLKLNSGYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEIL 63
Query: 66 DSG-VPREEIFVTTKLWGTQQRDPEA--ALDLSLQRLGLDYVDLYLIHWPVPLNASSITD 122
D G V REE+F+T+K+W T + +A +D+ L L L YVDL LIHWP +
Sbjct: 64 DEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWP-----QGYAE 118
Query: 123 GNYLTFPRTADGKI---DIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLA 179
G L FP +GK+ D+D +++TW+ + K+GK ++IG+SNF+ I+ +
Sbjct: 119 GAEL-FPAGENGKMRYSDVD-----YLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWD 172
Query: 180 ANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSS---------TILTD 230
A + PA Q+E+HP Q +L ++CK KGI++ YSPLG+ S +LT+
Sbjct: 173 AAE--VKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGNPGSAFFRKDGDPNVLTN 230
Query: 231 PTIEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKINK 288
+ GIA + PA I++ W G +PKSV PQRI NL + D L+ E++ KI+
Sbjct: 231 EVVAGIAKAHGKTPAQIILRWFVDSGLSAIPKSVTPQRISENLAVFDFQLTAEEISKIDG 290
Query: 289 LTES 292
+ ++
Sbjct: 291 INKN 294
>7298972 [R] KOG1577 Aldo/keto reductase family proteins
Length = 329
Score = 201 bits (511), Expect = 1e-51
Identities = 120/306 (39%), Positives = 181/306 (58%), Gaps = 30/306 (9%)
Query: 10 LKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIR---D 66
L N G +PV+G+GTW++ +E+ A+ +AL+ GYRHIDTA +YGNE+A+G+ ++ D
Sbjct: 7 LTFNNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLD 66
Query: 67 SG-VPREEIFVTTKLWGTQQR--DPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDG 123
+G V REE+F+ TK+ R + E + SL+ L LDYVDLYL+H P +N + DG
Sbjct: 67 AGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININE--DG 124
Query: 124 NYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPD 183
+F +G +++D+ N W M+ L + G TK+IGVSNFS + LL
Sbjct: 125 ---SFKLDKEGLMEVDVTT-NHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCK- 179
Query: 184 FIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGS-------SSSTILTD------ 230
I PA NQIE H L Q +L+D+CKS+ I + AYSPLGS + + I+ D
Sbjct: 180 -IRPANNQIEHHVYLQQRDLVDFCKSENITVTAYSPLGSKGIAKFNAGAGIVRDLPDLMD 238
Query: 231 -PTIEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKIN 287
P ++ IA+ + PA +L+ W G +PKS NP R+K NL + D L+ E++ K++
Sbjct: 239 IPEVKEIAASHGKTPAQVLLRWIIDTGVSAIPKSTNPARLKQNLDVFDFELTAEEVAKLS 298
Query: 288 KLTESV 293
L +++
Sbjct: 299 SLDQNI 304
>7292407 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 200 bits (509), Expect = 2e-51
Identities = 126/316 (39%), Positives = 178/316 (55%), Gaps = 26/316 (8%)
Query: 11 KLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIR----D 66
K N G I +GLGT+ S E D AV+ A+ GYRHIDTA YGNE VG +R +
Sbjct: 10 KHNDGTHIQGIGLGTFASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAE 69
Query: 67 SGVPREEIFVTTKLWGT--QQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGN 124
+ RE+IF+TTKLW + E A +L+ +GLDYVDLYLIHWP S G+
Sbjct: 70 GVIKREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPF----SYKYRGD 125
Query: 125 YLTFPRTADGKID-IDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPD 183
P+ A+G+++ +DI+ ++ TW M+ L G TK+IGVSNF+ + + LLA
Sbjct: 126 NELIPKDANGEVELVDID---YLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLLANCK- 181
Query: 184 FIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSS-----TILTDPTIEGIAS 238
I P NQIE+HP L Q +LI CK GIL+ A+SPLG ++ T + D ++ IA
Sbjct: 182 -IKPIHNQIEVHPALDQKKLIALCKKNGILVTAFSPLGRHNAELRTPTFMYDGKVQAIAD 240
Query: 239 KYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTED---LEKINKLTESV 293
KYN A ++I + G + LPKS NP+RI+ N + D L ED L+ +
Sbjct: 241 KYNKSIAQVVIRYVIELGTIPLPKSSNPKRIEENFNVFDFKLDAEDHAILDSYHNGERVA 300
Query: 294 GAKRYVAPDFSPFAIF 309
A++ + + PF ++
Sbjct: 301 HARQAIKSKYYPFNVY 316
>CE24243 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 199 bits (506), Expect = 4e-51
Identities = 118/299 (39%), Positives = 175/299 (58%), Gaps = 33/299 (11%)
Query: 9 SLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVG---KGIR 65
SLKLN+G SIP +GLGTW+S + A+ +A+ GYRHID A +Y N++ VG K I
Sbjct: 4 SLKLNSGYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEIL 63
Query: 66 DSG-VPREEIFVTTKLWGTQQRDPEA--ALDLSLQRLGLDYVDLYLIHWPVPLNASSITD 122
D G V REE+F+T+K+W T + +A +D+ L L L YVDL LIHWP +
Sbjct: 64 DEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWP-----QGYAE 118
Query: 123 GNYLTFPRTADGKI---DIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLA 179
G L FP +GK+ D+D +++TW+ + K+GK ++IG+SNF+ I+ +
Sbjct: 119 GAEL-FPAGENGKMRYSDVD-----YLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWD 172
Query: 180 ANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSS---------TILTD 230
A + PA Q+E+HP Q +L ++CK KGI++ YSPLG+ S +LT+
Sbjct: 173 AAE--VKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGNPGSAFFRKDGDPNVLTN 230
Query: 231 PTIEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKIN 287
+ GIA + PA I++ W G +PKSV PQRI N+ ++D LS E+++ I+
Sbjct: 231 EVVAGIAKAHGKTPAQIILRWFVDSGLSAIPKSVTPQRIIENISVIDFQLSAEEIQAID 289
>Hs20127592 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 198 bits (504), Expect = 7e-51
Identities = 120/289 (41%), Positives = 161/289 (55%), Gaps = 22/289 (7%)
Query: 10 LKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKG----IR 65
++L+T A +P+VGLGTWKSP AV A+ GYRHID A +Y NE VG+ I+
Sbjct: 5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64
Query: 66 DSGVPREEIFVTTKLWGTQQRDP--EAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDG 123
+ V RE++F+ +KLW T P A + +L+ L L Y+D+YLIHWP G
Sbjct: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWP-----QGFKSG 119
Query: 124 NYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPD 183
+ L FP+ D K + + F+ WE M+ L G KA+GVSNFS IE LL
Sbjct: 120 DDL-FPK--DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGL 176
Query: 184 FIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGS--------SSSTILTDPTIEG 235
P NQ+E HP L Q +LI YC SKGI + AYSPLGS ++L DP I+
Sbjct: 177 KYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKE 236
Query: 236 IASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLSTEDLE 284
IA+K+ A +LI + R +V+PKSV P RI N+++ D D E
Sbjct: 237 IAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEE 285
>Hs11386205 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 197 bits (501), Expect = 2e-50
Identities = 122/314 (38%), Positives = 182/314 (57%), Gaps = 31/314 (9%)
Query: 10 LKLNTGASIPVVGLGTWKSPEEDAYNAVVS---ALQNGYRHIDTAAIYGNEEAVGKGIR- 65
++LN G +PV+G GT+ PE AV A++ G+RHID+A +Y NEE VG IR
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 66 ---DSGVPREEIFVTTKLWGT--QQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSI 120
D V RE+IF T+KLW T Q + + AL+ SL++L LDYVDLYL+H+P+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 121 TDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAA 180
P+ +GK+ D + + TWE M+ +G K+IGVSNF+ + +E +L
Sbjct: 128 P------LPKDENGKVIFDTVDLS--ATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNK 179
Query: 181 NPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGS---------SSSTILTDP 231
P NQ+E HP L Q++L+D+CKSK I++ A+S LG+ +S +L DP
Sbjct: 180 PGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDP 239
Query: 232 TIEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKINKL 289
+ +A K+ PA I + + RG VVL KS N QRI+ N+++ + L++ED++ ++ L
Sbjct: 240 VLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGL 299
Query: 290 TESVGAKRYVAPDF 303
+ RYV DF
Sbjct: 300 NRNY---RYVVMDF 310
>Hs4503285 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 196 bits (499), Expect = 3e-50
Identities = 127/314 (40%), Positives = 181/314 (57%), Gaps = 33/314 (10%)
Query: 10 LKLNTGASIPVVGLGTW---KSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIR- 65
+KLN G +PV+G GT+ + P+ A AV A++ G+ HID+A +Y NEE VG IR
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 66 ---DSGVPREEIFVTTKLWGTQQRDPEA---ALDLSLQRLGLDYVDLYLIHWPVPLNASS 119
D V RE+IF T+KLW R PE AL+ SL+ L LDYVDLYLIH+PV S
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHR-PELVRPALERSLKNLQLDYVDLYLIHFPV-----S 121
Query: 120 ITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLA 179
+ G + P+ +GKI D + TWE M+ +G K+IGVSNF+ + +E +L
Sbjct: 122 VKPGEEV-IPKDENGKILFDTVD--LCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILN 178
Query: 180 ANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGS---------SSSTILTD 230
P NQ+E HP Q +L+D+CKSK I++ AYS LGS +S +L D
Sbjct: 179 KPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLED 238
Query: 231 PTIEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKINK 288
P + +A K+ PA I + + RG VVL KS N QRI+ N+++ + L++E+++ I+
Sbjct: 239 PVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDG 298
Query: 289 LTESVGAKRYVAPD 302
L +V RY+ D
Sbjct: 299 LNRNV---RYLTLD 309
>At2g37760 [R] KOG1577 Aldo/keto reductase family proteins
Length = 294
Score = 196 bits (498), Expect = 4e-50
Identities = 122/286 (42%), Positives = 158/286 (54%), Gaps = 33/286 (11%)
Query: 11 KLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVG----KGIRD 66
+LNTGA +P VGLGT+ A+ A++ GYRHID A+IYGNE+ +G K I D
Sbjct: 9 ELNTGAKLPCVGLGTYAM----VATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGD 64
Query: 67 SGVPREEIFVTTKLWGTQQ--RDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDG- 123
V REE+F+T+KLW D AL+ +LQ L +DYVDLYLIHWP L S+
Sbjct: 65 GFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTP 124
Query: 124 NYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPD 183
LT P + TW+ M+ L SGK +AIGVSNFS K + LL N
Sbjct: 125 EMLTKP--------------DITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLL--NVA 168
Query: 184 FIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSS-----TILTDPTIEGIAS 238
+ PA NQ+E HP Q L + CKSKG+ + YSPLGS S +L +P + +A
Sbjct: 169 RVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAE 228
Query: 239 KYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLS-TEDL 283
K A + + WG G+ VLPKS + R+K NL + D S EDL
Sbjct: 229 KLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDL 274
>Hs5453543 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 195 bits (495), Expect = 8e-50
Identities = 126/314 (40%), Positives = 181/314 (57%), Gaps = 33/314 (10%)
Query: 10 LKLNTGASIPVVGLGTW---KSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIR- 65
+KLN G +PV+G GT+ + P+ A A A++ G+RHID+A +Y NEE VG IR
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 66 ---DSGVPREEIFVTTKLWGTQQRDPEA---ALDLSLQRLGLDYVDLYLIHWPVPLNASS 119
D V RE+IF T+KLW R PE AL+ SL+ L LDYVDLYLIH+PV S
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHR-PELVRPALERSLKNLQLDYVDLYLIHFPV-----S 121
Query: 120 ITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLA 179
+ G + P+ +GKI D + TWE ++ +G K+IGVSNF+ + +E +L
Sbjct: 122 VKPGEEV-IPKDENGKILFDTVD--LCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 180 ANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGS---------SSSTILTD 230
P NQ+E HP Q +L+D+CKSK I++ AYS LGS +S +L D
Sbjct: 179 KPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLED 238
Query: 231 PTIEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKINK 288
P + +A K+ PA I + + RG VVL KS N QRI+ N+++ + L++E+++ I+
Sbjct: 239 PVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDG 298
Query: 289 LTESVGAKRYVAPD 302
L +V RY+ D
Sbjct: 299 LNRNV---RYLTLD 309
>Hs20127601 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 194 bits (492), Expect = 2e-49
Identities = 123/305 (40%), Positives = 176/305 (57%), Gaps = 30/305 (9%)
Query: 10 LKLNTGASIPVVGLGTWKSPE---EDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIR- 65
+KLN G +PV+G GT+ PE A A++ G+RHID+A +Y NEE VG IR
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 66 ---DSGVPREEIFVTTKLWGTQQRDPEA---ALDLSLQRLGLDYVDLYLIHWPVPLNASS 119
D V RE+IF T+KLW T R PE AL+ SL++ LDYVDLYLIH P+ S
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHR-PELVRPALENSLKKAQLDYVDLYLIHSPM-----S 121
Query: 120 ITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLA 179
+ G L+ P +GK+ DI + TWE M+ +G K+IGVSNF+ + +E +L
Sbjct: 122 LKPGEELS-PTDENGKVIFDIVD--LCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 180 ANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGS---------SSSTILTD 230
P NQ+E HP +++L+D+CKSK I++ AYS LGS +S +L D
Sbjct: 179 KPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLED 238
Query: 231 PTIEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKINK 288
P + +A K+ PA I + + RG VVL KS N QRI+ N+++ + L+ ED++ I+
Sbjct: 239 PVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDG 298
Query: 289 LTESV 293
L ++
Sbjct: 299 LDRNL 303
>At5g62420 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 190 bits (482), Expect = 3e-48
Identities = 115/296 (38%), Positives = 170/296 (56%), Gaps = 29/296 (9%)
Query: 11 KLNTGASIPVVGLGTW--KSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVG----KGI 64
+L G +IP++G+GT+ + E +AV A++ GYRH DTA IYG+EEA+G + I
Sbjct: 7 RLRCGETIPLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQAI 66
Query: 65 RDSGVPREEIFVTTKLWGTQQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGN 124
V R+++FVT+KLW + DP +AL +L+ +GLDY+D YL+HWP+ L G
Sbjct: 67 SYGTVQRDDLFVTSKLWSSDHHDPISALIQTLKTMGLDYLDNYLVHWPIKLK-----PGV 121
Query: 125 YLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDF 184
P+ + + D+ IEE TW+ M+ + G ++IGVSNFS K I LL DF
Sbjct: 122 SEPIPKEDEFEKDLGIEE-----TWQGMERCLEMGLCRSIGVSNFSSKKIFDLL----DF 172
Query: 185 --IVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGS-----SSSTILTDPTIEGIA 237
+ P+ NQ+E+HP Q +L C+ I + YSPLG S+ ++ P I+ IA
Sbjct: 173 ASVSPSVNQVEMHPLWRQRKLRKVCEENNIHVSGYSPLGGPGNCWGSTAVIEHPIIKSIA 232
Query: 238 SKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKINKLTE 291
K+NA PA + + WG S+G V+ KS N R+ N + L+ L +DL I+ L E
Sbjct: 233 LKHNATPAQVALRWGMSKGASVIVKSFNGARMIENKRALEIKLDDQDLSLIDHLEE 288
>7294701 [R] KOG1577 Aldo/keto reductase family proteins
Length = 305
Score = 190 bits (482), Expect = 3e-48
Identities = 113/300 (37%), Positives = 167/300 (55%), Gaps = 25/300 (8%)
Query: 7 SPSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIR- 65
+P+ L+ G ++P++GLGTW+SP E AV A+ GYRH D A IYGNE VG +R
Sbjct: 3 TPNFLLSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALRE 62
Query: 66 --DSG-VPREEIFVTTKLWGTQQRDP--EAALDLSLQRLGLDYVDLYLIHWPVPLNASSI 120
D G V R+E+F+T+KLW T + A + S++ LG+ Y++LYL+HWP+ + S
Sbjct: 63 KMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGS- 121
Query: 121 TDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAA 180
D Y T P T E+ +++ TW M++L G +AIGVSNF+ + + LL+
Sbjct: 122 -DNLYPTCPDTNKAA----FEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSV 176
Query: 181 NPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSS--------TILTDPT 232
+ P QIE HP L Q LI C I + AYS LGS + +L PT
Sbjct: 177 AK--LKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLGSGHTPYEKPGAYPLLQHPT 234
Query: 233 IEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLL---DLSTEDLEKINKL 289
I IA KY A +L+ + G +V+P+SV+ Q + N K + +L+ +D++ IN+L
Sbjct: 235 ILAIAEKYERTAAQVLLRFQTQSGIIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINEL 294
>YBR149w [R] KOG1577 Aldo/keto reductase family proteins
Length = 344
Score = 186 bits (471), Expect = 5e-47
Identities = 107/291 (36%), Positives = 171/291 (57%), Gaps = 14/291 (4%)
Query: 12 LNTGASIPVVGLGTWKSPEE--DAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIR---- 65
LN G IP +GLGT E+ + AV +A++ GYRHIDTA Y E VG+ I+
Sbjct: 27 LNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLE 86
Query: 66 DSGVPREEIFVTTKLWGTQQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDG-- 123
D + RE++F+TTK+W + + +L+ SL+ LGL+YVDL L HWP+ G
Sbjct: 87 DGSIKREDLFITTKVWPVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKGIS 146
Query: 124 NYLTFPRTADGKIDIDIEEWNFIKTWEKMQHL---PKSGKTKAIGVSNFSIKNIEALLAA 180
+ P GK + + ++++T+++++ + P + +AIGVSNFSI+ +E L+
Sbjct: 147 GLVKTPVDDSGKT-MYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIKE 205
Query: 181 NPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSSTILTDPTIEGIASKY 240
+ P NQ+E HP LPQ EL +C IL+ AYSPLGS + L P ++ +A KY
Sbjct: 206 CR--VKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVKKLAEKY 263
Query: 241 NAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLSTEDLEKINKLTE 291
N ++LIS+ +G +V+P+S+NP RI ++++ L+ ++L+++N E
Sbjct: 264 NVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFASLTKDELQELNDFGE 314
>Hs13899261 [R] KOG1577 Aldo/keto reductase family proteins
Length = 307
Score = 186 bits (471), Expect = 5e-47
Identities = 114/297 (38%), Positives = 162/297 (54%), Gaps = 21/297 (7%)
Query: 18 IPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIR----DSGVPREE 73
IP VGL +WK+ AV A+ GYRH D A Y NE VG GIR + V RE+
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 74 IFVTTKLWGTQQRDP--EAALDLSLQRLGLDYVDLYLIHWPV---PLNASSITDGNYLTF 128
+F+ TKLW T + E A SL+ L L+Y+DLYLIHWP+ P + I + L+F
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 129 ----PRTADGKID----IDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAA 180
PR D +D + + +F+ TWE M+ L +G K IGVSNF+ + +E LL
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 181 NPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSS--TILTDPTIEGIAS 238
P NQIE HP L Q LI +C+S+ + + AY PLG S ++ +P I+ IA
Sbjct: 184 PGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGVDLIDNPVIKRIAK 243
Query: 239 KYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKINKLTESV 293
++ PA ILI + R +V+P S+ P IK N+++ D L+ D++ I L ++
Sbjct: 244 EHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNL 300
>At2g21260 [R] KOG1577 Aldo/keto reductase family proteins
Length = 309
Score = 185 bits (469), Expect = 8e-47
Identities = 104/296 (35%), Positives = 167/296 (56%), Gaps = 24/296 (8%)
Query: 10 LKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIRDSG- 68
+ LN+G +P++GLG W+ +E+ + ++ A++ GYRH+D AA Y NE VG+ + ++
Sbjct: 3 ITLNSGFKMPIIGLGVWRMEKEELRDLIIDAIKIGYRHLDCAANYKNEAEVGEALTEAFT 62
Query: 69 ---VPREEIFVTTKLWGTQQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSI--TDG 123
V RE++F+TTKLW + A SL++L LDY+DL+L+H P+ + I TD
Sbjct: 63 TGLVKREDLFITTKLWSSDHGHVIEACKDSLKKLQLDYLDLFLVHIPIATKHTGIGTTDS 122
Query: 124 NYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPD 183
DG +DID + TW M+ L G ++IG+SN+ + LA +
Sbjct: 123 -----ALGDDGVLDID-TTISLETTWHDMEKLVSMGLVRSIGISNYDVFLTRDCLAYSK- 175
Query: 184 FIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSS--------TILTDPTIEG 235
I PA NQIE HP + L+ +C+ GI + A++PLG +++ + L DP ++
Sbjct: 176 -IKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGATANAEWFGTVSCLDDPVLKD 234
Query: 236 IASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKINKL 289
+A KY A I++ WG R VV+PK+ P+R++ N ++ D LS ED+E I +
Sbjct: 235 VAEKYKQTVAQIVLRWGIQRNTVVIPKTSKPERLEENFQVFDFQLSKEDMEVIKSM 290
>At2g21250 [R] KOG1577 Aldo/keto reductase family proteins
Length = 309
Score = 182 bits (463), Expect = 4e-46
Identities = 104/294 (35%), Positives = 165/294 (55%), Gaps = 20/294 (6%)
Query: 10 LKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIRDSG- 68
+ LN+G +P+VGLG W+ +E + +++A++ GYRH+D AA Y NE VG + ++
Sbjct: 3 ITLNSGFKMPIVGLGVWRMEKEGIRDLILNAIKIGYRHLDCAADYRNETEVGDALTEAFK 62
Query: 69 ---VPREEIFVTTKLWGTQQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNY 125
V RE++F+TTKLW + A SL++L LDY+DL+L+H+PV A+ T
Sbjct: 63 TGLVKREDLFITTKLWNSDHGHVIEACKDSLKKLQLDYLDLFLVHFPV---ATKHTGVGT 119
Query: 126 LTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFI 185
DG +DID + TW M+ L G ++IG+SN+ + LA + I
Sbjct: 120 TDSALGDDGVLDID-TTISLETTWHDMEKLVSMGLVRSIGISNYDVFLTRDCLAYSK--I 176
Query: 186 VPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSS--------TILTDPTIEGIA 237
PA NQIE HP + L+ +C+ GI + A++PLG +++ + L DP ++ +A
Sbjct: 177 KPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGATANAEWFGTVSCLDDPVLKDVA 236
Query: 238 SKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKINKL 289
KY A +++ WG R VV+PK+ P R++ N ++ D LS ED+E I +
Sbjct: 237 EKYKKTVAQVVLRWGIQRKTVVIPKTSKPARLEENFQVFDFELSKEDMEVIKSM 290
>7292408 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 182 bits (461), Expect = 7e-46
Identities = 115/317 (36%), Positives = 170/317 (53%), Gaps = 30/317 (9%)
Query: 4 SNESPSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVG-- 61
S++ P +K N G I +GLGT+ S D A + A+ GYRHIDTA Y NE VG
Sbjct: 2 SSKIPYVKHNNGTQIQSIGLGTYTSLGGDCERATLHAIDVGYRHIDTAYFYENENEVGAA 61
Query: 62 --KGIRDSGVPREEIFVTTKLW--GTQQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNA 117
+ I + + RE+I +TTKLW + + E A +LQ GL YVDLYL+HWP
Sbjct: 62 VQRKIAEGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPY---- 117
Query: 118 SSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEAL 177
S + G+ P D K ++++ + +++ TW +M+ L + G TK+IGVSNF+ + + L
Sbjct: 118 SYVYRGDNEMMP--TDAKGEVELNDIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRL 175
Query: 178 LAANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLG-----SSSSTILTDPT 232
LA I P NQIE HP L Q +LI CK I++ AY PLG + + D
Sbjct: 176 LANCK--IKPIHNQIECHPALNQKKLIALCKKNDIVVTAYCPLGRPNPAEKTPNYIYDAK 233
Query: 233 IEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDL------- 283
++ I KY A +++ + G + LPKS NP+RI+ N ++ D L ED
Sbjct: 234 VQAIGDKYKKSTAQVVLRYLIEIGTIPLPKSSNPKRIEENFQIFDFQLDAEDHAILDSYN 293
Query: 284 --EKINKLTESVGAKRY 298
E++ +T ++ +K Y
Sbjct: 294 TGERLIPMTHAIKSKNY 310
>7302301 [R] KOG1577 Aldo/keto reductase family proteins
Length = 311
Score = 181 bits (458), Expect = 2e-45
Identities = 114/294 (38%), Positives = 161/294 (53%), Gaps = 28/294 (9%)
Query: 4 SNESPSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKG 63
+N +P+++LN G +P +GLGTWKS E DAY++ AL GYRH+DTA +Y NE VG+
Sbjct: 2 TNLAPTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQA 61
Query: 64 ----IRDSGVPREEIFVTTKLWGTQQRDP---EAALDLSLQRLGLDYVDLYLIHWPVPLN 116
I + V REE+FVTTKL G DP E A LSL LGL+YVDLYL+H PV
Sbjct: 62 ISEKIAEGVVTREEVFVTTKLGGI-HHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQK 120
Query: 117 ASSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEA 176
F ++ +++ + +++ TW +M+ L G T++IG+SNF+ E
Sbjct: 121 -----------FHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTER 169
Query: 177 LLAANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSST-----ILTDP 231
+LA I P NQ+E HP Q +L ++ K G++I AY PL L D
Sbjct: 170 VLANCR--IRPVVNQVECHPGFQQRQLREHAKRHGLVICAYCPLARPQPARQWPPFLYDE 227
Query: 232 TIEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDL 283
+ +A KY A I + + G V LPKS N RI+ N ++ D LS +D+
Sbjct: 228 HAQNLAKKYGRTTAQICLRYLVQLGVVPLPKSSNKARIEENFRVFDFELSPDDV 281
>CE10936 [R] KOG1577 Aldo/keto reductase family proteins
Length = 283
Score = 176 bits (445), Expect = 5e-44
Identities = 99/285 (34%), Positives = 154/285 (53%), Gaps = 22/285 (7%)
Query: 9 SLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIR--- 65
S+KLNTG P++GLGT+K + + +AL GYR DTA +Y NE+ +G +
Sbjct: 2 SIKLNTGYDCPLIGLGTYKIIGDQVLPVLDAALTAGYRLFDTAKVYNNEKEIGDALEILL 61
Query: 66 -DSGVPREEIFVTTKLWGTQQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGN 124
+ RE+IF+TTK+ + + +D SL L Y+D+YLIH+P S G+
Sbjct: 62 PKHNLKREDIFITTKMHPNTVENVKKLVDESLSLLKTSYIDMYLIHYP-----KSFDYGD 116
Query: 125 YLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDF 184
+T I TW + +GK +++GVS+F I+++E L +F
Sbjct: 117 QDPMNKTLR------------IATWNDLWECKNAGKIRSVGVSSFEIRHLEELKDLGKNF 164
Query: 185 IVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSSTILTDPTIEGIASKYNAEP 244
P NQ+E HP + EL +YCKS+GI +A+S L + T+L+ I +A KY+
Sbjct: 165 -PPCCNQVEYHPHFTREELKNYCKSEGIFFQAFSSLARHNETLLSSEIITRLAEKYHVPK 223
Query: 245 ANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLSTEDLEKINKL 289
+L+SW S+ ++PKS NP+R+ NLK + L E+++KI L
Sbjct: 224 TTVLLSWATSQKVGIIPKSTNPERLAQNLKTVLLEEEEVKKICNL 268
>Hs5174695 [R] KOG1577 Aldo/keto reductase family proteins
Length = 326
Score = 175 bits (444), Expect = 7e-44
Identities = 115/313 (36%), Positives = 167/313 (52%), Gaps = 34/313 (10%)
Query: 1 MSTSNESPSLKLNTGASIPVVGLGTWKSPEEDAYNAVVS----ALQNGYRHIDTAAIYGN 56
M S S + L+ G SIP++GLGT+ P+ A + A+ GYRHID A IY N
Sbjct: 1 MDLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQN 60
Query: 57 EEAVGKGIRDS----GVPREEIFVTTKLWGTQQRDPEAA---LDLSLQRLGLDYVDLYLI 109
E VG+ IR+ V RE+IF KLW T PE L+ +L+ L LDYVDLY+I
Sbjct: 61 EHEVGEAIREKIAEGKVRREDIFYCGKLWATNHV-PEMVRPTLERTLRVLQLDYVDLYII 119
Query: 110 HWPVPLNASSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNF 169
P+ + G+ + +PR +GK + N TWE M+ +G K++GVSNF
Sbjct: 120 EVPM-----AFKPGDEI-YPRDENGKWLY--HKSNLCATWEAMEACKDAGLVKSLGVSNF 171
Query: 170 SIKNIEALLAANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSS------ 223
+ + +E +L P +NQ+E HP Q +L+ +C+ I+I AYSPLG+S
Sbjct: 172 NRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWV 231
Query: 224 ---SSTILTDPTIEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLS- 279
S +L D + + +YN A I++ + RG VV+PKS N +RIK N ++ D S
Sbjct: 232 NVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSL 291
Query: 280 ----TEDLEKINK 288
+D+E +NK
Sbjct: 292 TEEEMKDIEALNK 304
>CE06776 [R] KOG1577 Aldo/keto reductase family proteins
Length = 317
Score = 175 bits (444), Expect = 7e-44
Identities = 114/325 (35%), Positives = 168/325 (51%), Gaps = 48/325 (14%)
Query: 4 SNESPSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKG 63
S+ + S+KL+ G +PV+GLGTW+S + AV +A++ GYR IDTA++Y NEEA+G
Sbjct: 2 SSATASIKLSNGVEMPVIGLGTWQSSPAEVITAVKTAVKAGYRLIDTASVYQNEEAIGTA 61
Query: 64 IR----DSGVPREEIFVTTKLWGTQQRDP---EAALDLSLQRLGLDYVDLYLIHWPVPLN 116
I+ + V REE+F+TTK W T + P E L SL++L L+YVDLYL H P N
Sbjct: 62 IKELLEEGVVKREELFITTKAW-THELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAFN 120
Query: 117 ASSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEA 176
++ P +E+ W + + K+G KA+GVSN++ I
Sbjct: 121 DDM---SEHIASP----------VED-----VWRQFDAVYKAGLAKAVGVSNWNNDQISR 162
Query: 177 LLAANPDFIVPAAN-QIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSSTILTDPT--- 232
LA + P N Q+E+H PQ + +D+CK I + +Y+ LGS T PT
Sbjct: 163 ALALG---LTPVHNSQVELHLYFPQHDHVDFCKKHNISVTSYATLGSPGRVNFTLPTGQK 219
Query: 233 --------------IEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDL 278
+ +A K + PA +L+ + RG +LPKS+ RIK N ++ D
Sbjct: 220 LDWAPAPSDLQDQNVLALAEKTHKTPAQVLLRYALDRGCAILPKSIQENRIKENFEVFDF 279
Query: 279 STEDLEKINKLTESVGAKRYVAPDF 303
S + E I KL ES ++R DF
Sbjct: 280 SLTE-EDIAKLEESKNSQRLFLQDF 303
>CE17230 [R] KOG1577 Aldo/keto reductase family proteins
Length = 333
Score = 174 bits (440), Expect = 2e-43
Identities = 116/302 (38%), Positives = 164/302 (53%), Gaps = 30/302 (9%)
Query: 9 SLKLNTGASIPVVGLGTWKSPEEDAYN-AVVSALQNGYRHIDTAAIYGNEEAVGKGIRD- 66
S+ LNTGA +P+ GLGTW+ +E A+ +AL GYR IDTA +Y NE +GK + +
Sbjct: 5 SIPLNTGAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVLHEY 64
Query: 67 --SG-VPREEIFVTTKLWGTQQ--RDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSIT 121
SG + RE+IFVT+KL T D ++ L+ L L+Y+DLYLIH P P
Sbjct: 65 ISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKHQ--- 121
Query: 122 DGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAAN 181
+G++ P +G ++ + E I TW ++ L K GK KA+GVSNFS ++AL A
Sbjct: 122 EGSFA--PLMENG--ELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAA 177
Query: 182 PDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSSTI------------LT 229
+ PA Q+E H PQ EL CK G+ + AY+PLGS L
Sbjct: 178 E--VKPANQQVECHIYWPQQELRALCKKLGVTVTAYAPLGSPGRKAARPDGVWPEGDPLL 235
Query: 230 DPTIEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKIN 287
+P ++ +A+KY+ A ILI G +PKSV+P RI N+ D LS ED+ +N
Sbjct: 236 EPIVKQLAAKYHKTAAQILIRHLTQHGISTIPKSVSPDRIVENISTFDFKLSDEDMHTLN 295
Query: 288 KL 289
+
Sbjct: 296 SI 297
>7294572 [R] KOG1577 Aldo/keto reductase family proteins
Length = 317
Score = 167 bits (424), Expect = 1e-41
Identities = 106/291 (36%), Positives = 153/291 (52%), Gaps = 23/291 (7%)
Query: 7 SPSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIRD 66
+P++KLN G +P++GLGT+ S + + AV A+ GYRHIDTA Y NE VGK IRD
Sbjct: 4 APTVKLNNGYEMPILGLGTYNSKDNEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRD 63
Query: 67 ----SGVPREEIFVTTKLWGTQQRDPEAALDL---SLQRLGLDYVDLYLIHWPVPLNASS 119
V RE+IF+ TKLW DPE + L GLDY+DLYL+H PV
Sbjct: 64 KIAEGVVKREDIFLVTKLWNI-FHDPERVEGICRKQLSNFGLDYIDLYLMHMPV---GYK 119
Query: 120 ITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLA 179
D N L P+ D + + + +++ T++ M+ L K G ++IGVSNF+ + + +LA
Sbjct: 120 YVDDNTL-LPKNEDDV--LQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVLA 176
Query: 180 ANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSSTI-----LTDPTIE 234
I P NQ+E P L Q L +CK + + Y+PLG I + P +
Sbjct: 177 NCE--IKPVTNQVECSPALNQKALTAFCKKNDVTLTGYTPLGKPKPDIQKPDFIYSPEVA 234
Query: 235 GIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDL 283
IA KY I++ + G + +PKS N RI N + D L+ E++
Sbjct: 235 VIAKKYGKTTPQIVLRYLVGLGVIPIPKSSNTNRISENFDIFDFELTAEEM 285
>SPAC2F3.05c [R] KOG1577 Aldo/keto reductase family proteins
Length = 275
Score = 167 bits (423), Expect = 2e-41
Identities = 103/289 (35%), Positives = 158/289 (54%), Gaps = 39/289 (13%)
Query: 10 LKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGI----R 65
+KLN G P G++ +++V +ALQ GYRHID+A +Y NE G+ I
Sbjct: 6 VKLNNGLKCPQFAYGSYMVNRTKCFDSVYAALQCGYRHIDSAQMYHNEADCGRAILKFME 65
Query: 66 DSGVPREEIFVTTKLWGTQ-QRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGN 124
++G RE+I+ T+KL + +++D S++ GL Y+DL+L+H P
Sbjct: 66 ETGTKREDIWFTSKLNDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPYG---------- 115
Query: 125 YLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDF 184
+ I++W+ ++ + GK +AIGVSNF +I+ LL ++P
Sbjct: 116 -------------------DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPK- 155
Query: 185 IVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSSTILTDPTIEGIASKYNAEP 244
I+P NQIE+HP Q +++DYC+SKGI + AY+PL + + IASKYN
Sbjct: 156 IIPCVNQIELHPFCSQQKVVDYCESKGIQLAAYAPLVHGEK--FGNKQLLAIASKYNKSE 213
Query: 245 ANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKINKLTE 291
A I+I + RG++VLPKS P+RIK N + D +S ED+EK+ L E
Sbjct: 214 AQIMIRYCLQRGFIVLPKSSTPRRIKENGDVFDFEISKEDMEKLYNLDE 262
>SPAP32A8.02 [R] KOG1577 Aldo/keto reductase family proteins
Length = 283
Score = 164 bits (415), Expect = 2e-40
Identities = 102/285 (35%), Positives = 150/285 (51%), Gaps = 35/285 (12%)
Query: 3 TSNESPSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGK 62
+ ES ++ L G IP +G G + + Y V AL +GYRHIDTAA+YGNE+ GK
Sbjct: 4 SQTESTTVTLTNGMVIPRIGFGAFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDICGK 63
Query: 63 GIRD----SGVPREEIFVTTKLWG-TQQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNA 117
I D + V R +IF+T+KL + AA+ SL LG Y+DL+LI P
Sbjct: 64 AIVDWCEKNNVKRTDIFLTSKLANCSDYYSTRAAIRSSLHHLG-TYIDLFLIQSP----- 117
Query: 118 SSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEAL 177
A GK + I +W+ M+ SG +++GVSN+ +K+++ L
Sbjct: 118 --------------AGGK-------KSRIASWKAMEEFVDSGDIRSVGVSNYGVKHLQEL 156
Query: 178 LAANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSSTILTDPTIEGIA 237
A+NP F P NQIE+HP L Q +++ YC+S I IEAYSPL + L D + IA
Sbjct: 157 YASNPKF-YPCVNQIELHPFLSQDDIVKYCQSHDIAIEAYSPL--THGIRLNDEKLVPIA 213
Query: 238 SKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLSTED 282
K N A +LI W +GY+ + KS + + ++L + + + D
Sbjct: 214 KKLNISVAQLLIRWSLQKGYIPIIKSTKKEHMLSDLDVFNFTIPD 258
>CE10934 [R] KOG1577 Aldo/keto reductase family proteins
Length = 297
Score = 164 bits (414), Expect = 2e-40
Identities = 98/290 (33%), Positives = 155/290 (52%), Gaps = 28/290 (9%)
Query: 9 SLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIR--- 65
S KLN+G +IP VG GT+K E+ A+ +AL GYR DTA Y NE+ +G+ ++
Sbjct: 12 SQKLNSGYNIPFVGFGTYKVTGENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILL 71
Query: 66 -DSGVPREEIFVTTKLWGTQQRDPEAA---LDLSLQRLGLDYVDLYLIHWPVPLNASSIT 121
G+ R ++F+T+K + + EA ++ SLQ L DY+D+YL+H+P P N S
Sbjct: 72 PKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKP-NDSDND 130
Query: 122 DGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAAN 181
D N + + A +E ++ +GK ++IGVSN+ I ++E L
Sbjct: 131 DVNNAEYRKIA----------------YEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYA 174
Query: 182 PDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSSTILTDPTIEGIASKYN 241
+ P ANQ+E HP + L YCK K I +A+S L ++ DP + +A K+N
Sbjct: 175 K--VPPCANQLEYHPHFARIPLQKYCKEKNIFFQAFSSLARHEPKLIEDPVVVELAKKHN 232
Query: 242 AEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKINKL 289
+L++W + ++PKSV P RI N K++D L+ ED++ + L
Sbjct: 233 TSVPLVLLAWALRQNVGIVPKSVTPSRIVENFKVIDIALTPEDIQSLTAL 282
>Hs17450865 [R] KOG1577 Aldo/keto reductase family proteins
Length = 310
Score = 162 bits (409), Expect = 8e-40
Identities = 111/313 (35%), Positives = 164/313 (51%), Gaps = 43/313 (13%)
Query: 1 MSTSNESPSLKLNTGASIPVVGLGTWK---SPEEDAYNAVVSALQNGYRHIDTAAIYGNE 57
M+ +S S++LN G +PV+G GT+ +P+ A A A+ G+RHID+A +Y NE
Sbjct: 1 MTDLKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNE 60
Query: 58 EAVGKGI----RDSGVPREEIFVTTKLWGTQQRDP--EAALDLSLQRLGLDYVDLYLIHW 111
E VG+ I D V REEIF T KLW T R AL+ SL++LG DYVDL++IH
Sbjct: 61 EEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHV 120
Query: 112 PVPLNASSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSI 171
P + G L P+ A G+I ++ E TWE K
Sbjct: 121 PFAMKP-----GKEL-LPKDASGEIILETVE--LCDTWENQGDKHKL------------- 159
Query: 172 KNIEALLAANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSST----- 226
+E +L P NQ+E HP L Q++L+++CKSK I++ AYS LGS
Sbjct: 160 --LELILNKPGLRYKPTCNQVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDP 217
Query: 227 ----ILTDPTIEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LST 280
+L +P ++ IA K++ P + + + RG VVL KS + +RIK N ++ D L+
Sbjct: 218 DCPHLLEEPILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTP 277
Query: 281 EDLEKINKLTESV 293
ED++ I+ L ++
Sbjct: 278 EDMKAIDGLNRNL 290
>CE01200 [R] KOG1577 Aldo/keto reductase family proteins
Length = 287
Score = 162 bits (409), Expect = 8e-40
Identities = 95/285 (33%), Positives = 160/285 (55%), Gaps = 31/285 (10%)
Query: 17 SIPVVGLGTWKSPEEDAYNAVVSA-LQNGYRHIDTAAIYGNEEAVGKGIRD----SGVPR 71
++P++G+GTW+ +E+ V+ A + GYR IDTA +Y NE +G+ + +G+ R
Sbjct: 10 NMPLIGIGTWQVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPANGLKR 69
Query: 72 EEIFVTTKLWGTQQRDPEA--ALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNYLTFP 129
E+I++T+KL + +A +++ SL L ++Y+DL LIHWP G+ L
Sbjct: 70 EDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWP----------GSSLKSE 119
Query: 130 RTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIVPAA 189
A+ K+ ++ +W M + GK +++GVSNF I ++E L +VPA
Sbjct: 120 NPANKKLRVE--------SWNVMCEMMAEGKLRSVGVSNFEICHLEEL--KKDSNVVPAV 169
Query: 190 NQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSS--STILTDPTIEGIASKYNAEPANI 247
NQ+E HP Q +L+ YC I +AYS LGS + + +P I+ +A KYN E +
Sbjct: 170 NQVEYHPHFHQDDLVKYCNENNIHFQAYSSLGSPTYRKQLSEEPLIKELAQKYNVEIPVL 229
Query: 248 LISWGASRGYVVLPKSVNPQRIKTNLKL--LDLSTEDLEKINKLT 290
L+ + +G VLP++ NP+ + TN K+ L ++ ED++++ LT
Sbjct: 230 LLGFAYCQGISVLPRTTNPEHVATNFKVTKLAITQEDIDRLLALT 274
>YJR096w [R] KOG1577 Aldo/keto reductase family proteins
Length = 282
Score = 161 bits (407), Expect = 1e-39
Identities = 102/281 (36%), Positives = 144/281 (50%), Gaps = 37/281 (13%)
Query: 11 KLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGI-----R 65
KL+ G IP + LGT+ P V ++ GYRH DTA +YGNE+ VG GI
Sbjct: 7 KLSNGFKIPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWLNE 66
Query: 66 DSG-VPREEIFVTTKLWGTQQ--RDPEAALDLSLQRL-GLDYVDLYLIHWPVPLNASSIT 121
D G REEIF TTKLW +Q + +AA+ L + GL Y+DL LIH P+
Sbjct: 67 DPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL-------- 118
Query: 122 DGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAAN 181
+G+ L ++TW MQ G K+IGVSN+ K+I+ LL
Sbjct: 119 EGSKLR------------------LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWP 160
Query: 182 PDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSSTILTDPTIEGIASKYN 241
P NQIEI P + + EL DYCKSKG+++EA++PL +T+P + + + +
Sbjct: 161 ELKHKPVVNQIEISPWIMRQELADYCKSKGLVVEAFAPLCHGYK--MTNPDLLKVCKEVD 218
Query: 242 AEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLSTED 282
P +LI W GY+ LPK+ +R++ NL + D
Sbjct: 219 RNPGQVLIRWSLQHGYLPLPKTKTVKRLEGNLAAYNFELSD 259
>CE27788 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 159 bits (403), Expect = 4e-39
Identities = 105/306 (34%), Positives = 159/306 (51%), Gaps = 45/306 (14%)
Query: 4 SNESPSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKG 63
S++ P L+ G +P +GLGTW+ E+ + +A+ GYRHIDTA +Y NE +G
Sbjct: 2 SSKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTVIRNAVLAGYRHIDTATLYQNEHQIGDA 61
Query: 64 IRD---SGV-PREEIFVTTKLWGTQQRDP--EAALDLSLQRLGLDYVDLYLIHWPVPLNA 117
+ + G+ RE+IF+TTK + + E AL SL+RL LDYVDLYL H P A
Sbjct: 62 LAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIP----A 117
Query: 118 SSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEAL 177
S+ DG++ + D+ +E+ W + + G TKAIGVSNF+ I +
Sbjct: 118 STKDDGSF---------RSDVKVED-----IWRGFEKVYGLGLTKAIGVSNFNESQIVRI 163
Query: 178 LAANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGS--------------- 222
+ N + A+Q+E+H LPQ + CK ILI AY+ LGS
Sbjct: 164 M--NIQKVPIHASQLELHLYLPQKAHRELCKKHNILITAYATLGSPGRMSVVGSNGRPLF 221
Query: 223 ----SSSTILTDPTIEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDL 278
+S + D ++ +A KY+ PA IL+ G +V+PK+ NP+R+K N+ + D
Sbjct: 222 ESTQNSENEMNDKHVKALAQKYSKTPAQILLRATVEMGIIVIPKTTNPERMKENINIFDF 281
Query: 279 STEDLE 284
+ + E
Sbjct: 282 NISNAE 287
>Hs17465400 [R] KOG1577 Aldo/keto reductase family proteins
Length = 384
Score = 157 bits (396), Expect = 2e-38
Identities = 118/375 (31%), Positives = 171/375 (45%), Gaps = 77/375 (20%)
Query: 10 LKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIRDS-- 67
++L+T A +P+VGLGTW+S AV A+ YRHID A Y N+ VG+ I++
Sbjct: 5 VELSTKAKMPIVGLGTWRSLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQ 64
Query: 68 --GVPREEIFVTTKL------WGTQQRDP--EAALDLSLQRLGLDYVDLYLIHWP----- 112
V RE++F+ +K+ W T P A + +L+ L L Y+D+YLIHWP
Sbjct: 65 EKAVMREDLFIVSKVHMAHLVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS 124
Query: 113 -----------------VPLNASSITDGN----YLTFPRTADGKIDIDIE------EWNF 145
LN + D + ++ + +T D D + + F
Sbjct: 125 LKKWYADVVFSKHQDPETLLNRTKCPDADSSKLFILYLQTGDDFFPKDDKGNMISGKGTF 184
Query: 146 IKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIVPAANQ-------------- 191
+ WE M+ L G KA+GVSNF+ IE LL P NQ
Sbjct: 185 LDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQNSLGTMQNRAGFPR 244
Query: 192 --------IEIHPQLPQTELIDYCKSKGILIEAYSPLGS--------SSSTILTDPTIEG 235
+E HP L Q +LI YC SKGI + AYSPLGS ++L DP I+
Sbjct: 245 DEDCLLLQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKE 304
Query: 236 IASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLSTEDLEKINKLTESVGA 295
IA+K+ A +LI + R V+PKS+ P I N+++ D D E L+ +
Sbjct: 305 IAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFN--- 361
Query: 296 KRYVAPDFSPFAIFE 310
+ + A DF F+ E
Sbjct: 362 RNWRAFDFKEFSHLE 376
>CE24244 [R] KOG1577 Aldo/keto reductase family proteins
Length = 339
Score = 155 bits (391), Expect = 9e-38
Identities = 95/301 (31%), Positives = 161/301 (52%), Gaps = 28/301 (9%)
Query: 9 SLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIRD-- 66
++ LN+G +PV+G GTW+ P+ A V AL+ GYRHID+A + N+E V GI+D
Sbjct: 6 TVTLNSGYEMPVIGYGTWQLPKNLAAERVRDALEAGYRHIDSALSFKNQEEVAAGIKDWC 65
Query: 67 --SGVPREEIFVTTKLWGTQQRDPEA--ALDLSLQRLGLDYVDLYLIHWPVPLNASSITD 122
V REE+F+++K+W T +D L+ Y+DL +IHWP A
Sbjct: 66 KIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFGW-AEDEPP 124
Query: 123 GNYLTFPRTADGKI---DIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLA 179
G +PR A+GK+ D+D +++TW+ ++ +SGK ++IG++NF+I +E +
Sbjct: 125 GERGLWPRGANGKMRYSDVD-----YLETWKALEDAHRSGKIRSIGLANFNIGQVEQVWT 179
Query: 180 ANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSS---------TILTD 230
I PA Q+E++P L Q E+ +C+ KGI++ A+ G+ S +L +
Sbjct: 180 KG--LIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAFMLTGNPGSALYRKHEDPNLLYN 237
Query: 231 PTIEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDLEKINK 288
T++ IA + +L+ W L KS +RI+ N+ + L+++++ +I
Sbjct: 238 ETLQSIAKGHGKSVVQVLVRWAIDLRTTALVKSSESKRIRQNINIFKFRLTSQEIARIKA 297
Query: 289 L 289
L
Sbjct: 298 L 298
>7294573 [R] KOG1577 Aldo/keto reductase family proteins
Length = 252
Score = 151 bits (382), Expect = 1e-36
Identities = 93/256 (36%), Positives = 141/256 (54%), Gaps = 20/256 (7%)
Query: 7 SPSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKG--- 63
+P++KLN G +P++GLGT+ + AV AL+ GYRHIDTA +Y NE +GK
Sbjct: 4 APTVKLNNGYEMPILGLGTYNLKKSRCEAAVCHALEMGYRHIDTAYLYRNEGIIGKVLAK 63
Query: 64 -IRDSGVPREEIFVTTKLWGT--QQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSI 120
I D + RE++F+ TKLW + + + A D+ L+ LG+DY+DLYL+H PV I
Sbjct: 64 LIGDQKLKREQVFLVTKLWDIYHEPKMVKYACDMQLKLLGVDYIDLYLMHSPV--GVDYI 121
Query: 121 TDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAA 180
+D + + D+D ++ T+ M+ L G +++G+SNF+ ++ LL
Sbjct: 122 SDEDLMPHENGQLRTNDVD-----YVDTYRSMEQLVHLGLVRSLGLSNFNANQLKRLLEN 176
Query: 181 NPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSS-----TILTDPTIEG 235
I PA QIE HP+L Q LI+ CK I + AYSPLG + TD +
Sbjct: 177 CQ--IKPANLQIECHPELVQVPLIELCKFHNITVVAYSPLGRPKACNPLPDYYTDSKLLA 234
Query: 236 IASKYNAEPANILISW 251
+A+KY PA I++ +
Sbjct: 235 LAAKYGKTPAQIILRY 250
>At1g59950 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 150 bits (380), Expect = 2e-36
Identities = 103/289 (35%), Positives = 149/289 (50%), Gaps = 28/289 (9%)
Query: 18 IPVVGLGTWKSPEEDAY---NAVVSALQNGYRHIDTAAIYGNEEAVGKGIRDS---GV-- 69
+PV+ LGT SP + V+ A++ GYRH DT+ Y EE +G+ + ++ G+
Sbjct: 15 MPVLALGTAASPPPEPIVLKRTVLEAIKLGYRHFDTSPRYQTEEPLGEALAEAVSLGLIQ 74
Query: 70 PREEIFVTTKLWGTQQRDPEA--ALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNYLT 127
R E+FVT+KLW A+ SL+ L LDY+DLYLIHWPV S G Y
Sbjct: 75 SRSELFVTSKLWCADAHGGLVVPAIQRSLETLKLDYLDLYLIHWPV-----SSKPGKY-K 128
Query: 128 FPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIVP 187
FP D + +D E W +M+ + G K IGVSNFS K ++ +L+ I P
Sbjct: 129 FPIEEDDFLPMDYET-----VWSEMEECQRLGVAKCIGVSNFSCKKLQHILSIAK--IPP 181
Query: 188 AANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGS-----SSSTILTDPTIEGIASKYNA 242
+ NQ+E+ P Q +L + CKSKGI++ AYS LGS + I+ ++ IA
Sbjct: 182 SVNQVEMSPVWQQRKLRELCKSKGIVVTAYSVLGSRGAFWGTHKIMESDVLKEIAEAKGK 241
Query: 243 EPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLSTEDLEKINKLTE 291
A + + W G ++ KS R++ NLK+ D S + EK TE
Sbjct: 242 TVAQVSMRWAYEEGVSMVVKSFRKDRLEENLKIFDWSLTEEEKQRISTE 290
>YHR104w [R] KOG1577 Aldo/keto reductase family proteins
Length = 327
Score = 148 bits (373), Expect = 1e-35
Identities = 103/311 (33%), Positives = 155/311 (49%), Gaps = 26/311 (8%)
Query: 7 SPSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIR- 65
S + LN G +P+VGLG WK ++ N + A++ GYR D A YGNE+ VG+GIR
Sbjct: 2 SSLVTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRK 61
Query: 66 ---DSGVPREEIFVTTKLWGTQQRDP--EAALDLSLQRLGLDYVDLYLIHWPVPLNASSI 120
+ V R++IFV +KLW + AL +L +GLDY+DLY IH+P+
Sbjct: 62 AISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPF 121
Query: 121 TDGNYLTFPRTADGKIDIDIEEWN--FIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALL 178
+ F AD + I E + I T+ ++ G K+IGVSNF I+ LL
Sbjct: 122 EEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLL 181
Query: 179 AANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSS------------ST 226
I P A QIE HP L Q L+++CK I + AYS G S T
Sbjct: 182 RGCR--IKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKTTPT 239
Query: 227 ILTDPTIEGIASKY-NAEPANILISWGASRGYVVLPKSVNPQRIKTNL---KLLDLSTED 282
+ + I+ ++ + + + +L+ W RG V+PKS +R+ NL K L+ ++
Sbjct: 240 LFENDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIPKSSKKERLLGNLEIEKKFTLTEQE 299
Query: 283 LEKINKLTESV 293
L+ I+ L ++
Sbjct: 300 LKDISALNANI 310
>At1g59960 [R] KOG1577 Aldo/keto reductase family proteins
Length = 326
Score = 147 bits (371), Expect = 2e-35
Identities = 103/295 (34%), Positives = 153/295 (50%), Gaps = 33/295 (11%)
Query: 8 PSLKLNTGAS----IPVVGLGTWKSPEEDAY---NAVVSALQNGYRHIDTAAIYGNEEAV 60
P+L + +G S +PV+G GT SP + V+ A++ GYRH DT+ Y EE +
Sbjct: 7 PTLAIRSGPSGHHSMPVLGFGTAASPLPEPTMLKETVIEAIKLGYRHFDTSPRYQTEEPI 66
Query: 61 GKGIRDS---GV--PREEIFVTTKLWGTQQRDPEA--ALDLSLQRLGLDYVDLYLIHWPV 113
G+ + ++ G+ R E FVTTKLW A+ SL+ L LDY+DLY+IHWPV
Sbjct: 67 GEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYIIHWPV 126
Query: 114 PLNASSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKN 173
S G Y FP D + +D E W +M+ + G K IGVSNFS K
Sbjct: 127 -----SSKPGKY-KFPIDEDDFMPMDFEV-----VWSEMEECQRLGLAKCIGVSNFSCKK 175
Query: 174 IEALLAANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGS-----SSSTIL 228
++ +L+ I P+ NQ+E+ P Q +L + C+S I++ AYS LGS + I+
Sbjct: 176 LQHILSIAT--IPPSVNQVEMSPIWQQRKLRELCRSNDIVVTAYSVLGSRGAFWGTPKIM 233
Query: 229 TDPTIEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLDLS-TED 282
++ IA A + + W +G ++ KS +R++ NLK+ D S TED
Sbjct: 234 ESDVLKEIAEAKEKTVAQVSMRWAYEQGVSMVVKSFTKERLEENLKIFDWSLTED 288
>CE06751 [R] KOG1577 Aldo/keto reductase family proteins
Length = 287
Score = 147 bits (370), Expect = 2e-35
Identities = 96/290 (33%), Positives = 150/290 (51%), Gaps = 31/290 (10%)
Query: 11 KLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIRDSGVP 70
KL G IP + LGT+++ + + AV AL+ GYR DTA Y NE+ +G ++ +P
Sbjct: 3 KLKNGQEIPKLALGTYEAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTL-LP 61
Query: 71 R-----EEIFVTTKLWGTQQRDPEAAL----DLSLQRLGLDYVDLYLIHWPVPLNASSIT 121
R E+I++T+K++ ++ + + SL+ L Y+DL L+H+P PL+ +
Sbjct: 62 RHNICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPRPLDTEDLN 121
Query: 122 DGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAAN 181
+ N + TW ++ L GK ++IGVSN+ +IE + +
Sbjct: 122 ENNKMYRK-----------------DTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYI 164
Query: 182 PDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSSTILTDPTIEGIASKYN 241
I P NQIE HP + L YC IL +A+SPLG + T+L D T+E IA +
Sbjct: 165 T--IEPQVNQIEYHPHFQRKVLRAYCNKNEILFQAFSPLGRGNKTLLGDSTMERIALCHK 222
Query: 242 AEPANILISWGASRGYVVLPKSVNPQRIKTNLK--LLDLSTEDLEKINKL 289
AN++++W Y V+ KSV P R+ N L+LS ++ EKIN L
Sbjct: 223 TTVANVILAWIMKGKYGVVAKSVTPSRVAENYTSLSLELSDDEFEKINGL 272
>Hs22054710 [R] KOG1577 Aldo/keto reductase family proteins
Length = 418
Score = 146 bits (369), Expect = 3e-35
Identities = 101/276 (36%), Positives = 146/276 (52%), Gaps = 46/276 (16%)
Query: 6 ESPSLKLNTGASIPVVGLGTWK---SPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGK 62
+S S++LN G +P++G GT+ +P+ A A A+ G+RHID A Y NEE VGK
Sbjct: 5 QSHSVRLNDGHVMPMLGFGTYAPDHTPKSKAGEATEVAIDAGFRHIDAAFFYQNEEEVGK 64
Query: 63 GIR----DSGVPREEIFVTTKLWGTQQRDPE---AALDLSLQRLGLDYVDLYLIHWPV-- 113
IR D V RE+IF TT+LW T R PE AL+ SL++L LDYVDL++IH P+
Sbjct: 65 AIREKIADGPVKREDIFYTTELWTTFFR-PELVRPALEGSLKKLQLDYVDLFIIHNPLAM 123
Query: 114 -------------PLNASSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGK 160
P + SS+ P+ A G I D + TWE ++ ++G
Sbjct: 124 KLLRRQKGNSHRKPSSLSSVFQPGEELLPKDASGNIIFDTVDLR--DTWEALEKCKEAGL 181
Query: 161 TKAIGVSNFSIKNIEALLAANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPL 220
TK+IGVSNF+ K +E +L ++ P Q++L+++CKSK I++ AY L
Sbjct: 182 TKSIGVSNFNHKLLELIL---------NKPGLKYKPTCNQSKLLEFCKSKDIVLVAYRAL 232
Query: 221 GS---------SSSTILTDPTIEGIASKYNAEPANI 247
S S +L +PT++ IA KYN P +
Sbjct: 233 ASHRDPNWMDPDSPYLLEEPTLKSIAKKYNRSPGQV 268
>SPAC19G12.09 [R] KOG1577 Aldo/keto reductase family proteins
Length = 284
Score = 144 bits (364), Expect = 1e-34
Identities = 94/288 (32%), Positives = 153/288 (52%), Gaps = 46/288 (15%)
Query: 18 IPVVGLGT--WKSPEEDAYNAVVSALQN----GYRHIDTAAIYGNEEAVGKGIRDSGVPR 71
+P G+GT +K + + +V +++N G+ HID A +YGNEE VG ++++ VPR
Sbjct: 12 VPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVALKEANVPR 71
Query: 72 EEIFVTTKLWGTQQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNYLTFPRT 131
++F+T+K+ PE AL+ SL++LG DY+DLYL+H P+P
Sbjct: 72 SKLFITSKVMHNVDNIPE-ALNESLRKLGTDYLDLYLLHSPIPF---------------- 114
Query: 132 ADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIVPAANQ 191
+ KI I + W+ M+ +G ++GVSNF I ++E LL + I P NQ
Sbjct: 115 YEKKIPIS-------EGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTST--ITPRVNQ 165
Query: 192 IEIHPQLPQT--ELIDYCKSKGILIEAYSPLGSSSSTILTD---PTIE---GIASKYNAE 243
IE HPQ+ + L+++C+SKGI++E Y PL S ++ D P E + SKY+
Sbjct: 166 IEFHPQVYKAAKPLVEFCQSKGIIVEGYGPL----SPLVRDAQGPVAEFTKSLESKYHVS 221
Query: 244 PANILISWGASRGYVVLPKSVNPQRIK--TNLKLLDLSTEDLEKINKL 289
IL+ W S+G + + + +R+K N L D++++ L
Sbjct: 222 DTQILLKWAYSKGVIPITTTSKIERMKECLNFDSFTLDKADIDELGTL 269
>Hs20545142 [R] KOG1577 Aldo/keto reductase family proteins
Length = 280
Score = 138 bits (348), Expect = 9e-33
Identities = 100/288 (34%), Positives = 138/288 (47%), Gaps = 64/288 (22%)
Query: 10 LKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEE--AVGKGIRDS 67
L LN G +P++GLGTWKSP AV A+ GY HID A + NE A+ + +R+
Sbjct: 5 LVLNNGTKMPILGLGTWKSPPGRVTEAVNVAINVGYCHIDCAH-HENEVGVAIQEKLREQ 63
Query: 68 GVPREEIFVTTKLWGTQQRDPEAALDLSLQRLGLDYVDLYLIHWP--VPLNASSITDGNY 125
V REE+F+ T W PLN GN
Sbjct: 64 VVKREELFIVT--------------------------------WEGIFPLNEL----GNV 87
Query: 126 LTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFI 185
+ + N + TW M+ L KAIG+SNF+ +E LL
Sbjct: 88 VP-------------SDTNILDTWAAMEELVDEWLMKAIGISNFNHLQVERLLNKPGLKY 134
Query: 186 VPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSS--------STILTDPTIEGIA 237
P NQIE HP L Q +LI YC+SKGI++ AYSP+G+ S ++L DP I+ IA
Sbjct: 135 KPVVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPVGTPSRPWVNPEDPSLLRDPRIKAIA 194
Query: 238 SKYNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKLLD--LSTEDL 283
+K+N A +LI + R V+PKSV P+ I N K+ D L+++D+
Sbjct: 195 AKHNKTTAQVLIRFPMQRNLGVIPKSVTPELIADNFKVFDFELNSQDM 242
>YDL124w [R] KOG1577 Aldo/keto reductase family proteins
Length = 312
Score = 134 bits (337), Expect = 2e-31
Identities = 100/303 (33%), Positives = 149/303 (49%), Gaps = 50/303 (16%)
Query: 12 LNTGASIP---VVGLGT--WKSPEEDA------YNAVVSALQ-NGYRHIDTAAIYGNEEA 59
LN G IP ++G GT +K+ E DA +V AL+ G HID A IY
Sbjct: 10 LNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDAAEIYRTYPE 69
Query: 60 VGKGIRDSGVPREEIFVTTKLWGTQQR---DPEAALDLSLQRLGLDYVDLYLIHWPVPLN 116
VGK + + PR IF+T K + Q + P LDL+L+++G DYVDLYL+H P
Sbjct: 70 VGKALSLTEKPRNAIFLTDK-YSPQIKMSDSPADGLDLALKKMGTDYVDLYLLHSPF--- 125
Query: 117 ASSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEA 176
+ ++ + + W+ M+ L KSGK K IGVSNF++++++
Sbjct: 126 -------------------VSKEVNGLSLEEAWKDMEQLYKSGKAKNIGVSNFAVEDLQR 166
Query: 177 LLAANPDFIVPAANQIEIHPQLPQTE--LIDYCKSKGILIEAYSPLGSSSSTILTDPT-- 232
+L + P NQIE P L + +C+ IL+EAYSPLG D +
Sbjct: 167 ILKVAE--VKPQVNQIEFSPFLQNQTPGIYKFCQEHDILVEAYSPLGPLQKKTAQDDSQP 224
Query: 233 ----IEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRIK--TNLKLLDLSTEDLEKI 286
++ ++ KY A I++ W RG + + S PQRI NL DL+ E+++KI
Sbjct: 225 FFEYVKELSEKYIKSEAQIILRWVTKRGVLPVTTSSKPQRISDAQNLFSFDLTAEEVDKI 284
Query: 287 NKL 289
+L
Sbjct: 285 TEL 287
>CE15543 [R] KOG1577 Aldo/keto reductase family proteins
Length = 376
Score = 134 bits (337), Expect = 2e-31
Identities = 104/323 (32%), Positives = 156/323 (48%), Gaps = 46/323 (14%)
Query: 8 PSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQN-GYRHIDTAAIYGNEEAVGKGIRD 66
P+ L+ +P++GLGT S ++AV+ +++ GYR IDTA YG E+ +G +++
Sbjct: 3 PTTVLSNNVEMPLIGLGTTHSGGY-YHDAVLHSIKKCGYRLIDTAKRYGVEKQLGIAVKN 61
Query: 67 SGVPREEIFVTTKLWGTQQRDPEA-ALDLSLQRLGLDYVDLYLIH------WPVPLNASS 119
VPREE+F++TKLW D A S ++L DY+D+Y+IH W V +
Sbjct: 62 CSVPREEMFLSTKLWPVDCGDEVYNAFQTSCEKLQTDYLDMYMIHMPQLPDWIVNQKETK 121
Query: 120 ----------ITDGNY--------LTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKT 161
DG + L F A I + I K K+ K
Sbjct: 122 EKTWRQMELLYEDGKFGFCFKCFKLAFGE-ATSYIALKISCNELCKLNLKLPMSISRSKN 180
Query: 162 ------------KAIGVSNFSIKNIEALLAANPDFIVPAANQIEIHPQLPQTELIDYCKS 209
++IGVSN+SI++++ LL I+P ANQ+E+HP Q +L +YC
Sbjct: 181 PQTNFTIITEHVRSIGVSNYSIEDLDELLEFAS--ILPHANQVELHPWFHQADLKNYCDE 238
Query: 210 KGILIEAYSPLGSSSSTILTDPTIEGIASKYNAEPANILISWGASRGYVVLPKSVNPQRI 269
GIL Y PL + L D T+ IASKY PA I + W + +PKS + +R+
Sbjct: 239 LGILTMGYCPL--AKGKYLEDETLCKIASKYQKSPAQICLRWSIQQNVPTVPKSTDCRRL 296
Query: 270 KTNLKLLD--LSTEDLEKINKLT 290
K N + D LS ED+ +N +
Sbjct: 297 KENTNVFDFELSAEDMNTLNSFS 319
>Hs20470761 [R] KOG1577 Aldo/keto reductase family proteins
Length = 222
Score = 133 bits (335), Expect = 3e-31
Identities = 90/243 (37%), Positives = 118/243 (48%), Gaps = 44/243 (18%)
Query: 10 LKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIRDS-- 67
++LNT A +P+VGLGTWKSP V A+ GYRHID A +Y NE VG+ I++
Sbjct: 5 VELNTKAKMPIVGLGTWKSPLGKVKEVVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64
Query: 68 --GVPREEIFVTTKLWGTQQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNY 125
V RE++F+ KLW T P LG D +
Sbjct: 65 EKAVKREDLFIINKLWPTFFERP----------LGYKSGDDFF----------------- 97
Query: 126 LTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFI 185
D K ++ + F+ WE M+ L G KA+GVSNF+ IE LL
Sbjct: 98 -----RKDDKGNMIGGKAMFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKY 152
Query: 186 VPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGS--------SSSTILTDPTIEGIA 237
P NQ+E HP L Q +LI YC SKGI I AYSPLGS ++L DP I+ IA
Sbjct: 153 KPVTNQVECHPYLTQEKLIQYCHSKGITIMAYSPLGSPDRLWAKPEDPSLLEDPKIKEIA 212
Query: 238 SKY 240
+++
Sbjct: 213 ARH 215
>CE06112 [R] KOG1577 Aldo/keto reductase family proteins
Length = 301
Score = 122 bits (305), Expect = 9e-28
Identities = 83/292 (28%), Positives = 140/292 (47%), Gaps = 28/292 (9%)
Query: 9 SLKLNTGASIPVVGLGTWK-SPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIR-- 65
+ K + G +P +GLG + ++D ++ +AL++GYR DTA +Y NE +G ++
Sbjct: 11 AFKFSDGYEMPKIGLGISRIETQQDLDVSIEAALKSGYRQFDTANLYKNETFLGNSLKKY 70
Query: 66 --DSGVPREEIFVTTKLWGTQQR---DPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSI 120
G+ RE++F+TTK+ + + E L SL L DYVDL LIH+P
Sbjct: 71 LPQFGLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIHYPRD------ 124
Query: 121 TDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAA 180
R D +I + W+ ++ +SG+ ++IGVSN+ + ++ +
Sbjct: 125 ---------RDTGNDDDYEINKSRRKIVWQTLEKAKESGRVRSIGVSNYEVYHLVEMFEY 175
Query: 181 NPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGSSSSTILTDPTIEGIASKY 240
I P NQ E P L + L +C I++++YS L IL + + + KY
Sbjct: 176 AK--IRPVLNQYEYQPYLTRPTLKKFCDLNNIVVQSYSSLCWGDKEILQEKPLVDLCQKY 233
Query: 241 NAEPANILISWGASRGYVVLPKSVNPQRIKTNLK---LLDLSTEDLEKINKL 289
N P IL ++ ++PKS P RI NL + L+ ++L+ + L
Sbjct: 234 NQTPQAILYAFAHCSNTSMIPKSATPSRIHDNLHNTIKIKLTEDELKSLRSL 285
>Hs20537171 [R] KOG1577 Aldo/keto reductase family proteins
Length = 241
Score = 117 bits (292), Expect = 3e-26
Identities = 88/298 (29%), Positives = 127/298 (42%), Gaps = 80/298 (26%)
Query: 12 LNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIRDS---- 67
LN G +P++GLGTW SP AV A+ GY HID A +Y NE VG IR+
Sbjct: 7 LNNGTKMPILGLGTWNSPPGQVTEAVKVAINVGYCHIDCAHVYQNENDVGVAIREKLREQ 66
Query: 68 GVPREEIFVTTKLWGTQQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNYLT 127
V EE+F+T+KL ++
Sbjct: 67 VVKCEELFITSKLCFKPGKE---------------------------------------F 87
Query: 128 FPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIVP 187
FP G ++ N + TW M+ L G KAIG+SNF
Sbjct: 88 FPLDEPGNGNVVPSNSNILDTWAGMEELVDEGLVKAIGISNF------------------ 129
Query: 188 AANQIEIHPQLPQTELIDYCKSKGILIEAYSPLGS--------SSSTILTDPTIEGIASK 239
N + Q +LI YC+SKGI++ AYS S ++L DP I+ I +K
Sbjct: 130 --NHL-------QEKLIQYCQSKGIMVTAYSSFSSPDRPWAKPEDPSLLEDPRIKAITAK 180
Query: 240 YNAEPANILISWGASRGYVVLPKSVNPQRIKTNLKL--LDLSTEDLEKINKLTESVGA 295
+N A +LI + R VV+PKSV P+ I N K+ +L+++D+ + + G+
Sbjct: 181 HNKTTAQVLIWFPMQRNLVVIPKSVTPECIAENFKVFNFELNSQDMTTLFSYNRTGGS 238
>SPBC28F2.05c [R] KOG1577 Aldo/keto reductase family proteins
Length = 276
Score = 94.7 bits (234), Expect = 1e-19
Identities = 77/267 (28%), Positives = 126/267 (46%), Gaps = 48/267 (17%)
Query: 31 EDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIRDS-----GVPREEIFVTTKLWGTQQ 85
+D Y V+ AL G R ID+A Y NE+ + I+D + RE+I + TK+ + Q
Sbjct: 24 KDCYQQVIEALSLGIRVIDSAITYRNEKECEQAIQDFCHQNVNIKREDITLITKIPDSLQ 83
Query: 86 RDPEA--ALDLSLQRLGLDYVDLYLIH---WPVPLNASSITDGNYLTFPRTADGKIDIDI 140
A++ SL+R G +D+ LIH WPV
Sbjct: 84 GFERTWKAVEQSLRRTGRPKLDVVLIHSPKWPV--------------------------- 116
Query: 141 EEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIVPAANQIEIHPQLPQ 200
I++W + K G+ IGVSN++I ++E +++ +PA NQ+E +
Sbjct: 117 ---RRIESWRALLQHQKEGRINKIGVSNYNIHHLEEIISLG--LPLPAINQVEFSAFNNR 171
Query: 201 TELIDYCKSKGILIEAYSPLGSSSSTILTDPTIEGIASKYNAEPANILISWGASRGYVVL 260
+ YC + GIL++A+SPL + L+D + ++ KYN PANIL+ + +G +
Sbjct: 172 PTFLSYCFNHGILVQAFSPL--TRGYRLSDIRLLDLSLKYNKTPANILLRYCLQKGVSPI 229
Query: 261 PKSVNPQRIKTNLK----LLDLSTEDL 283
K+ + I N+K +LD S D+
Sbjct: 230 FKASSFVHIHENVKAEQFMLDPSDMDV 256
>Hs16156291 [R] KOG1577 Aldo/keto reductase family proteins
Length = 130
Score = 92.0 bits (227), Expect = 1e-18
Identities = 53/120 (44%), Positives = 74/120 (61%), Gaps = 9/120 (7%)
Query: 5 NESPSLKLNTGASIPVVGLGTW---KSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVG 61
N S+KLN G +P++G GT K + AV A+ GYRHID+A + NEE +G
Sbjct: 4 NRLLSVKLNDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIG 63
Query: 62 KGIR----DSGVPREEIFVTTKLWGTQQRDP--EAALDLSLQRLGLDYVDLYLIHWPVPL 115
+ IR + V R++IF TTK+WGT R + L++SL++L L Y+DLYL H+PVPL
Sbjct: 64 QAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPL 123
>CE06775 [R] KOG1577 Aldo/keto reductase family proteins
Length = 134
Score = 72.4 bits (176), Expect = 8e-13
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 4/84 (4%)
Query: 1 MSTSNESPSLKLNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAV 60
+ S+ L L+ S+P VGLGTW+S ED +AV +A++NGY IDTA+ Y NEE +
Sbjct: 39 LKNSDAKSHLTLSNAHSMPAVGLGTWQSNAEDVISAVKAAVKNGYSLIDTASGYNNEEFI 98
Query: 61 GKGIR----DSGVPREEIFVTTKL 80
G I+ + V RE++F+TTK+
Sbjct: 99 GTAIKEVIAEGVVKREDLFITTKV 122
>At1g60680 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 340
Score = 68.6 bits (166), Expect = 1e-11
Identities = 77/322 (23%), Positives = 134/322 (40%), Gaps = 79/322 (24%)
Query: 29 PEEDAYNAVVSALQNGYRHIDTAAIYG---NEEAVGKGIRDSGVPREEI------FVTTK 79
PE DA + A+ +G DT+ +YG NE +GK ++D + E+ F+
Sbjct: 29 PETDAIALLHHAINSGVTFFDTSDMYGPETNELLLGKALKDGVKEKVELATKFGFFIVEG 88
Query: 80 LWGTQQRDPE---AALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNYLTFPRTADGKI 136
+ DPE AA + SL+RL + +DLY H D ++
Sbjct: 89 EISEVRGDPEYVRAACEASLKRLDIACIDLYYQH--------------------RIDTRV 128
Query: 137 DIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIVPAANQIEIHP 196
I+I T +++ L + GK K IG+S S I A +P I + +
Sbjct: 129 PIEI-------TMRELKKLVEEGKIKYIGLSEASASTIRRAHAVHP--ITAVQIEWSLWS 179
Query: 197 QLPQTELIDYCKSKGILIEAYSPLG--------------------SSSSTI--------- 227
+ + ++I C+ GI I AYSPLG +++T+
Sbjct: 180 RDAEEDIIPICRELGIGIVAYSPLGRGFLAAGPKLAENLENDDFRKATTTLPRFQQENVD 239
Query: 228 ---LTDPTIEGIASKYNAEPANILISWGASRGYVV--LPKSVNPQRIKTNLKLLD--LST 280
+ + +A K PA + ++W +G V +P + + + N++ L L+
Sbjct: 240 HNKILFEKVSAMAEKKGCTPAQLALAWVHHQGDDVCPIPGTTKIENLNQNIRALSVKLTP 299
Query: 281 EDLEKINKLT--ESVGAKRYVA 300
E++ +++ L ESV +RY+A
Sbjct: 300 EEISELDSLAKPESVKGERYMA 321
>Hs22058392 [R] KOG1577 Aldo/keto reductase family proteins
Length = 156
Score = 67.8 bits (164), Expect = 2e-11
Identities = 49/155 (31%), Positives = 71/155 (45%), Gaps = 18/155 (11%)
Query: 152 MQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIVPAANQIEIHPQLPQTELIDYCKSKG 211
M+ L G KAIG+S F+ ++ +L P +IE L Q +LI YC+SKG
Sbjct: 1 MKELVDEGLVKAIGISKFNYSHVRRILNKRGLKYQPMVKEIEFCTYLTQKKLIQYCQSKG 60
Query: 212 ILIEAYSPLGS--------SSSTILTDPTIEGIASKYNAEPANILISWGASRGYVVLPKS 263
I++ AYSPL S++L D + I K+N A R VV PKS
Sbjct: 61 IMVTAYSPLDCLDRPWAKLKDSSVLEDARSKVITVKHNKTT--------AQRNLVVNPKS 112
Query: 264 VNPQRIKTNLK--LLDLSTEDLEKINKLTESVGAK 296
V + I N K +LS++D+ + + K
Sbjct: 113 VTQKCIAENFKAFYFELSSKDMTTLPSYNRNCALK 147
>Hs22060498 [R] KOG1577 Aldo/keto reductase family proteins
Length = 594
Score = 67.4 bits (163), Expect = 3e-11
Identities = 48/142 (33%), Positives = 68/142 (47%), Gaps = 18/142 (12%)
Query: 152 MQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIVPAANQIEIHPQLPQTELIDYCKSKG 211
M+ L G KAIG+S F+ ++ +L P +IE L Q +LI YC+SKG
Sbjct: 1 MKELVDEGLVKAIGISKFNYSHVRRILNKRGLKYQPMVKEIEFCTYLTQKKLIQYCQSKG 60
Query: 212 ILIEAYSPLGS--------SSSTILTDPTIEGIASKYNAEPANILISWGASRGYVVLPKS 263
I++ AYSPL S++L D + I K+N A R VV PKS
Sbjct: 61 IMVTAYSPLDCLDRPWAKLKDSSVLEDARSKVITVKHNKTT--------AQRNLVVNPKS 112
Query: 264 VNPQRIKTNLK--LLDLSTEDL 283
V + I N K +LS++D+
Sbjct: 113 VTQKCIAENFKAFYFELSSKDM 134
>SPAC1F7.12 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 340
Score = 67.0 bits (162), Expect = 3e-11
Identities = 82/346 (23%), Positives = 139/346 (39%), Gaps = 101/346 (29%)
Query: 17 SIPVVGLGT------WKSPEEDAYNAVVS-ALQNGYRHIDTAAIYG---NEEAVGKGIRD 66
++P +G G + E+A AV++ A G D++ +YG NEE +G+ +
Sbjct: 12 TVPAIGFGCMGLHAMYGPSSEEANQAVLTHAADLGCTFWDSSDMYGFGANEECIGRWFKQ 71
Query: 67 SGVPREEIFVTTKLWGTQQRDPEA--------------ALDLSLQRLGLDYVDLYLIHWP 112
+G R+EIF+ TK +++PE ALDLSL+RLG+D +DLY +H
Sbjct: 72 TG-RRKEIFLATKFG--YEKNPETGELSLNNEPDYIEKALDLSLKRLGIDCIDLYYVH-- 126
Query: 113 VPLNASSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIK 172
G+ I+ K ++ ++GK + IG+S S
Sbjct: 127 ------------------RFSGETPIE-------KIMGALKKCVEAGKIRYIGLSECSAN 161
Query: 173 NIEALLAANPDFIVPAANQIEIHP-----QLPQTELIDYCKSKGILIEAYSPLGSSSST- 226
I A P +A Q+E P + P+ ++ C+ I I Y+PLG T
Sbjct: 162 TIRRAAAVYP----VSAVQVEYSPFSLEIERPEIGVMKACRENNITIVCYAPLGRGFLTG 217
Query: 227 ----------------------------ILTDPTIEGIASKYNAEPANILISWGASRGYV 258
+ IE IA+ N P + ++W ++G
Sbjct: 218 AYKSPDDFPEGDFRRKAPRYQKENFYKNLELVTKIEKIATANNITPGQLSLAWLLAQGDD 277
Query: 259 VLPKSVNPQRIK--------TNLKLLDLSTEDLEKINKLTESVGAK 296
+LP +R+K +KL D + +++ + E +GA+
Sbjct: 278 ILP-IPGTKRVKYLEENFGALKVKLSDATVKEIREACDNAEVIGAR 322
>At1g60750 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 330
Score = 65.9 bits (159), Expect = 7e-11
Identities = 77/304 (25%), Positives = 133/304 (43%), Gaps = 65/304 (21%)
Query: 28 SPEEDAYNAVVSALQNGYRHIDTAAIYG---NEEAVGKGIRDSGVPREEIFVTTKLWGTQ 84
+PE +A + A+ G +DT+ IYG NE +GK ++D R+++ + TK T
Sbjct: 38 TPETNAVALLRHAINAGVTFLDTSDIYGPETNELLLGKALKDG--LRDKVELATKFGITA 95
Query: 85 QRD--------PE---AALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNYLTFPRTAD 133
D PE A + SL+RLG+ +DLY H D
Sbjct: 96 SEDGKFGFRGDPEYVRIACEASLKRLGVTCIDLYYQH--------------------RID 135
Query: 134 GKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIVPAANQIE 193
+ I+I T +++ L + GK K IG+S S I A +P I +
Sbjct: 136 TTLPIEI-------TIGELKKLVEEGKIKYIGLSEASASTIRRAHAVHP--ITAVQIEWS 186
Query: 194 IHPQLPQTELIDYCKSKGILIEAYSPLGS-------------SSSTILTDPTIEGIASKY 240
+ + + ++I C+ GI I AYSPLG ++ IL + ++ +A+K
Sbjct: 187 LWSRDVEEDIIPTCRELGIGIVAYSPLGRGFLGLPRFQQENLENNKILYE-KVQAMATKK 245
Query: 241 NAEPANILISWGASRGYVV--LPKSVNPQRIKTNLKLLD--LSTEDLEKINKLTES--VG 294
+ PA + ++W +G V +P + Q + N+ L L+ E++ ++ + + V
Sbjct: 246 SCTPAQLALAWVHHQGDDVCPIPGTSKIQNLNQNIGALSVKLTPEEMVELEAIAQPDFVK 305
Query: 295 AKRY 298
+RY
Sbjct: 306 GERY 309
>SPCC965.06 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 344
Score = 64.3 bits (155), Expect = 2e-10
Identities = 85/339 (25%), Positives = 132/339 (38%), Gaps = 90/339 (26%)
Query: 14 TGASIPVVGLGTWKSPEEDAY------NAVVSALQNGYRHIDTAAIYGN---EEAVGKGI 64
+G + LG W + + Y N + A G DTA IY N E +GK I
Sbjct: 21 SGLKVSAFSLGGWLTYGNEGYDVEHTKNCLKQAWDLGINTFDTAEIYSNGNSETVMGKAI 80
Query: 65 RDSGVPREEIFVTTKLW-----------GTQQRDPEAALDLSLQRLGLDYVDLYLIHWPV 113
++ G R E +TTK++ G ++ L+ SL+RLGL YVD+ + H P
Sbjct: 81 KELGWDRSEYVITTKVFFGAGTKLPNTTGLSRKHIIEGLNASLKRLGLPYVDVIMAHRPD 140
Query: 114 PLNASSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKN 173
P + +EE L + GK G S +S
Sbjct: 141 P----------------------SVPMEE-----VVRAFTQLIQDGKAFYWGTSEWSAFE 173
Query: 174 IEAL--LAANPDFIVPAANQIEIH---------PQLPQTELIDYCKS------KGILIEA 216
IE +A + I P A+Q + + LP ++ Y + GIL
Sbjct: 174 IEHAHHIATKYNLIAPVADQPQYNYLTRDHFEKDLLPLQQIYGYGATVWSPLKSGILTGK 233
Query: 217 YS---PLGSSSSTILTD-----PTIEG------------IASKYNAEPANILISWGASRG 256
Y+ P GS ST T T EG IA + A P+ + ++W
Sbjct: 234 YNDGIPEGSRLSTTFTSLAGQLQTPEGKTQLDQVRQISKIAEQIGATPSQLALAWTLKNP 293
Query: 257 YV--VLPKSVNPQRIKTNLKLLD----LSTEDLEKINKL 289
YV + + P++I N+K ++ L+ E L+KI+++
Sbjct: 294 YVSTTILGASKPEQIVENVKAVEFIDKLTPEILKKIDEI 332
>At1g60710 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 287
Score = 63.9 bits (154), Expect = 3e-10
Identities = 63/206 (30%), Positives = 96/206 (46%), Gaps = 44/206 (21%)
Query: 29 PEEDAYNAVVSALQNGYRHIDTAAIYG---NEEAVGKGIRDSGVPREEIFVTTKL---WG 82
PE +A + A+ +G +DT+ IYG NE +GK ++D GV RE++ + TK +
Sbjct: 29 PENEAIALIHHAIHSGVTLLDTSDIYGPETNEVLLGKALKD-GV-REKVELATKFGISYA 86
Query: 83 TQQR----DPE---AALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNYLTFPRTADGK 135
+R DPE AA + SL+RL + +DLY H D +
Sbjct: 87 EGKREVRGDPEYVRAACEASLKRLDIACIDLYYQH--------------------RVDTR 126
Query: 136 IDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIVPAANQIEIH 195
+ I+I T +++ L + GK K IG+S S I A +P I + +
Sbjct: 127 VPIEI-------TMGELKKLVEEGKIKYIGLSEASASTIRRAHAVHP--ITAVQIEWSLW 177
Query: 196 PQLPQTELIDYCKSKGILIEAYSPLG 221
+ + E+I C+ GI I AYSPLG
Sbjct: 178 TRDVEEEIIPTCRELGIGIVAYSPLG 203
>At1g60690 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 345
Score = 62.4 bits (150), Expect = 8e-10
Identities = 85/357 (23%), Positives = 148/357 (40%), Gaps = 88/357 (24%)
Query: 1 MSTSNESPSLKLNT-GASIPVVGLGTW--------KSPEEDAYNAVVSALQNGYRHIDTA 51
M+ S +KL + G + GLG PE +A + A+ +G +DT+
Sbjct: 1 MAESCRVRRIKLGSQGLEVSAQGLGCMGLTGHYGASKPETEAIALIHHAIHSGVTFLDTS 60
Query: 52 AIYG---NEEAVGKGIRDSGVPREEIFVTTKLW-----GTQQ--RDP---EAALDLSLQR 98
+YG NE +GK ++D GV RE++ + TK G ++ DP AA + SL+R
Sbjct: 61 DMYGPETNEILLGKALKD-GV-REKVELATKFGISYAEGNREIKGDPAYVRAACEASLKR 118
Query: 99 LGLDYVDLYLIHWPVPLNASSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKS 158
L + +DLY H D ++ I+I T +++ L +
Sbjct: 119 LDVTCIDLYYQH--------------------RIDTRVPIEI-------TMGELKKLIEE 151
Query: 159 GKTKAIGVSNFSIKNIEALLAANPDFIVPAANQIEIHPQLPQTELIDYCKSKGILIEAYS 218
GK K IG+S S I +P I + + + + E++ C+ GI I +YS
Sbjct: 152 GKIKYIGLSEASASTIRRAHTVHP--ITAVQLEWSLWTRDVEEEIVPTCRELGIGIVSYS 209
Query: 219 PLGS---SSSTILTD--------------------------PTIEGIASKYNAEPANILI 249
PLG +S L + + ++ K PA + +
Sbjct: 210 PLGRGFFASGPKLVENLDNNDFRKALPRFQQENLDHNKILYEKVSAMSEKKGCTPAQLAL 269
Query: 250 SWGASRGYVV--LPKSVNPQRIKTNLKLLD--LSTEDLEKINKLT--ESVGAKRYVA 300
+W +G V +P + + + N++ L L+ E++ ++ + ESV +RY+A
Sbjct: 270 AWVHHQGDDVCPIPGTTKIENLNQNIRALSVKLTPEEMSELETIAQPESVKGERYMA 326
>At4g33670 [C] KOG1576 Predicted oxidoreductase
Length = 319
Score = 61.2 bits (147), Expect = 2e-09
Identities = 66/229 (28%), Positives = 98/229 (41%), Gaps = 48/229 (20%)
Query: 13 NTGASIPVVGLGTWKSP---------EEDAYNAVVSALQNGYRHIDTAAIYG---NEEAV 60
NTG + VG G SP E+DA V A + G DT+ YG +E+ +
Sbjct: 11 NTGLKVSAVGFGA--SPLGSVFGPVAEDDAVATVREAFRLGINFFDTSPYYGGTLSEKML 68
Query: 61 GKGIRDSGVPREEIFVTTKLWGTQQRDPEAA------LDLSLQRLGLDYVDLYLIHWPVP 114
GKG++ VPR + V TK ++ +A +D SL+RL LDYVD+ H
Sbjct: 69 GKGLKALQVPRSDYIVATKCGRYKEGFDFSAERVRKSIDESLERLQLDYVDILHCH---- 124
Query: 115 LNASSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNI 174
D + G +D + E T +Q L + GKT+ IG++ +
Sbjct: 125 -------DIEF--------GSLDQIVSE-----TIPALQKLKQEGKTRFIGITGLPLDIF 164
Query: 175 EALLAANPDFIVPAANQIEIHPQLPQTELID---YCKSKGILIEAYSPL 220
+L P V H + + L+D Y KSKG+ + + SPL
Sbjct: 165 TYVLDRVPPGTVDVILSY-CHYGVNDSTLLDLLPYLKSKGVGVISASPL 212
>7299543 [C] KOG1576 Predicted oxidoreductase
Length = 345
Score = 57.4 bits (137), Expect = 3e-08
Identities = 59/209 (28%), Positives = 94/209 (44%), Gaps = 45/209 (21%)
Query: 31 EDAYNAVVSALQNGYRHIDTAAIYG---NEEAVGKGIRDSGVPREEIFVTTK-------- 79
E+ V A+++G +IDTA YG +EE +G ++D VPRE ++ TK
Sbjct: 53 EEGIKTVHEAVKSGINYIDTAPWYGQGRSEEVLGLALKD--VPRESYYIATKVARYELDY 110
Query: 80 --LWGTQQRDPEAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNYLTFPRTADGKID 137
++ + +++ SL+ LGLDYVD+ IH + F + +D
Sbjct: 111 DKMFDFSAKKTRESVEKSLKLLGLDYVDVIQIH--------------DIEFAK----DLD 152
Query: 138 IDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALL---AANPDFIVPAANQIEI 194
I I E T ++ L K GK + IGVS + I ++ L A D ++ A
Sbjct: 153 IVINE-----TLPTLEQLVKEGKARFIGVSAYPISVLKEFLTRTAGRLDTVLTYARYTLT 207
Query: 195 HPQLPQTELIDYCKSK--GILIEAYSPLG 221
L E +D+ KS+ G++ A LG
Sbjct: 208 DETL--LEYLDFFKSQNLGVICAAAHALG 234
>Hs17491434 [R] KOG1577 Aldo/keto reductase family proteins
Length = 117
Score = 56.2 bits (134), Expect = 6e-08
Identities = 28/75 (37%), Positives = 43/75 (57%), Gaps = 2/75 (2%)
Query: 12 LNTGASIPVVGLGTWKSPEEDAYNAVVSALQNGYRHIDTAAIYGNEEAVGKGIRDSGVPR 71
LN G ++GLGTWKSP AV A+ YRHID + ++ N++ + +++ V R
Sbjct: 2 LNNGTKTDMLGLGTWKSPPGQVAEAVKVAINTVYRHIDCSHVHQNKDQ--EQLKEQVVRR 59
Query: 72 EEIFVTTKLWGTQQR 86
E +F+ +K WG R
Sbjct: 60 EWLFIISKPWGICHR 74
>At1g60730 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 342
Score = 55.8 bits (133), Expect = 8e-08
Identities = 75/309 (24%), Positives = 131/309 (42%), Gaps = 80/309 (25%)
Query: 29 PEEDAYNAVVSALQNGYRHIDTAAIYG---NEEAVGKGIRDSGVPREEIFVTTKLWGTQ- 84
PE +A + A+ +G +DT+ IYG NE + K ++D GV RE++ + TK +G +
Sbjct: 38 PETEAIALIHHAIHSGVTFLDTSDIYGPETNELLLSKALKD-GV-REKVELATK-YGIRY 94
Query: 85 -------QRDP---EAALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNYLTFPRTADG 134
+ DP AA + SL R+ + +DLY H D
Sbjct: 95 AEGKVEFKGDPAYVRAACEASLMRVDVACIDLYYQH--------------------RIDT 134
Query: 135 KIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIVPAANQIE- 193
++ I+I T +++ L + GK K IG+S S I A +P A QIE
Sbjct: 135 RVPIEI-------TIGELKKLVEEGKIKYIGLSEASASTIRRAHAVHPI----TALQIEW 183
Query: 194 -IHPQLPQTELIDYCKSKGILIEAYSPLG--------------SSSSTI----------- 227
+ + + ++I C+ GI I AYSPLG ++ T+
Sbjct: 184 SLWSRDVEEDIIPTCRELGIGIVAYSPLGRGFFASGPKLVENLDNNDTLPRFQQENLDHN 243
Query: 228 -LTDPTIEGIASKYNAEPANILISWGASRGYVV--LPKSVNPQRIKTNLKLLD--LSTED 282
+ + ++ K PA + ++W +G V +P + + + N+ L L+ E+
Sbjct: 244 KILFEKVSAMSEKKGCTPAQLALAWVHHQGDDVCPIPGTTKIENLNQNIGALSVKLTPEE 303
Query: 283 LEKINKLTE 291
+ ++ L +
Sbjct: 304 MSELESLAQ 312
>At5g53580 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 324
Score = 54.3 bits (129), Expect = 2e-07
Identities = 73/313 (23%), Positives = 119/313 (37%), Gaps = 77/313 (24%)
Query: 17 SIPVVGLGTWK-----------SPEEDAYNAVVSALQNGYRHIDTAAIYG-------NEE 58
S+ +G GTW S ++ A AL+NG DTA YG +E
Sbjct: 5 SVSPMGFGTWAWGNQLLWGYQTSMDDQLQQAFELALENGINLFDTADSYGTGRLNGQSER 64
Query: 59 AVGKGIRDS-GV--PREEIFVTTKL----WGTQQRDPEAALDLSLQRLGLDYVDLYLIHW 111
+GK I++S G+ + E+ V TK W A SL RL +D + + +HW
Sbjct: 65 LLGKFIKESQGLKGKQNEVVVATKFAAYPWRLTSGQFVNACRASLDRLQIDQLGIGQLHW 124
Query: 112 PVPLNASSITDGNYLTFPRTADGKIDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSI 171
A ++E + W+ + + + G +A+GVSN+
Sbjct: 125 STASYA---------------------PLQE---LVLWDGLVQMYEKGLVRAVGVSNYGP 160
Query: 172 KNIEALLAANPDFIVPAAN-QIE---IHPQLPQTELIDYCKSKGILIEAYSPLG------ 221
+ + + VP + Q++ + Q E+ C GI + +YSPLG
Sbjct: 161 QQLVKIHDYLKTRGVPLCSAQVQFSLLSMGKEQLEIKSICDELGIRLISYSPLGLGMLTG 220
Query: 222 -SSSSTILTDP-----------------TIEGIASKYNAEPANILISWGASRGYVVLPKS 263
SSS + T P + IA K + I+W +G V +P
Sbjct: 221 KYSSSKLPTGPRSLLFRQILPGLEPLLLALSEIAKKRGKTMPQVAINWCICKGTVPIPGI 280
Query: 264 VNPQRIKTNLKLL 276
+ + ++ NL L
Sbjct: 281 KSVRHVEDNLGAL 293
>At1g10810 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 344
Score = 53.1 bits (126), Expect = 5e-07
Identities = 54/206 (26%), Positives = 90/206 (43%), Gaps = 46/206 (22%)
Query: 30 EEDAYNAVVSALQNGYRHIDTAAIYG---NEEAVGKGIRDSGVPREEIFVTTKLWGTQQR 86
E D + A+ +G +DT+ IYG NE +G+ ++D RE++ + TK +G +
Sbjct: 39 ETDLIALIHHAINSGITLLDTSDIYGPETNELLLGQALKDG--MREKVELATK-FGLLLK 95
Query: 87 DPE-----------AALDLSLQRLGLDYVDLYLIHWPVPLNASSITDGNYLTFPRTADGK 135
D + AA + SL+RLG+ +DLY H D
Sbjct: 96 DQKLGYRGDPAYVRAACEASLRRLGVSCIDLYYQH--------------------RIDTT 135
Query: 136 IDIDIEEWNFIKTWEKMQHLPKSGKTKAIGVSNFSIKNIEALLAANPDFIVPAANQIEIH 195
+ I++ T +++ L + GK K IG+S I A +P + + +
Sbjct: 136 VPIEV-------TIGELKKLVEEGKIKYIGLSEACASTIRRAHAVHP--LTAVQLEWSLW 186
Query: 196 PQLPQTELIDYCKSKGILIEAYSPLG 221
+ + ++I C+ GI I AYSPLG
Sbjct: 187 SRDVEEDIIPTCRELGIGIVAYSPLG 212
>At1g04420 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 412
Score = 51.6 bits (122), Expect = 1e-06
Identities = 70/267 (26%), Positives = 110/267 (40%), Gaps = 62/267 (23%)
Query: 2 STSNESPSLKL-NTGASIPVVGLGTW----KSPEEDAYNAVVSALQNGYRHIDTAAIYG- 55
ST N KL ++ +I V +GT ++ E++++ + A++ G IDTA Y
Sbjct: 51 STKNAMEYRKLGDSDLNISEVTMGTMTFGEQNTEKESHEMLSYAIEEGINCIDTAEAYPI 110
Query: 56 --NEEAVGK-----GIRDSGVPREEIFVTTKLWGTQQRDP----------------EAAL 92
+E GK R++I + TK+ G +R + ++
Sbjct: 111 PMKKETQGKTDLYISSWLKSQQRDKIVLATKVCGYSERSAYIRDSGEILRVDAANIKESV 170
Query: 93 DLSLQRLGLDYVDLYLIHWP---VPLNASSITDGNYLTFPRTADGKIDIDIEEWN----F 145
+ SL+RLG DY+DL IHWP VPL G + +W F
Sbjct: 171 EKSLKRLGTDYIDLLQIHWPDRYVPL-----------------FGDFYYETSKWRPSVPF 213
Query: 146 IKTWEKMQHLPKSGKTKAIGVSNFSIKNI-----EALLAANPDFIVPAANQIEIHPQLP- 199
+ Q L GK + IGVSN + + A L P IV N + +
Sbjct: 214 AEQLRAFQDLIVEGKVRYIGVSNETSYGVTEFVNTAKLEGLPK-IVSIQNGYSLLVRCRY 272
Query: 200 QTELIDYC--KSKGILIEAYSPLGSSS 224
+ +L++ C K+ + + AYSPLG S
Sbjct: 273 EVDLVEVCHPKNCNVGLLAYSPLGGGS 299
>Hs4504825 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 367
Score = 48.9 bits (115), Expect = 9e-06
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 17/118 (14%)
Query: 14 TGASIPVVGLGTWKS-----PEEDAYNAVVSALQNGYRHIDTAAIY--GNEEAV-GKGIR 65
+G + +GLGTW + +E A + A NG DTA +Y G E V G I+
Sbjct: 45 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIK 104
Query: 66 DSGVPREEIFVTTKL-WGTQQRDPEA--------ALDLSLQRLGLDYVDLYLIHWPVP 114
G R + +TTK+ WG + L SL+RL L+YVD+ + P P
Sbjct: 105 KKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDP 162
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.313 0.133 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,259,593
Number of Sequences: 60738
Number of extensions: 831801
Number of successful extensions: 1907
Number of sequences better than 1.0e-05: 76
Number of HSP's better than 0.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 1556
Number of HSP's gapped (non-prelim): 88
length of query: 310
length of database: 30,389,216
effective HSP length: 106
effective length of query: 204
effective length of database: 23,950,988
effective search space: 4886001552
effective search space used: 4886001552
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)