ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0056 good R KOG0254 General function prediction only Predicted transporter (major facilitator superfamily)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0056 13632 15503 624
(624 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHL047c [R] KOG0254 Predicted transporter (major facilitator sup... 737 0.0
YHL040c [R] KOG0254 Predicted transporter (major facilitator sup... 632 0.0
YCL073c [R] KOG0254 Predicted transporter (major facilitator sup... 494 e-139
YKR106w [R] KOG0254 Predicted transporter (major facilitator sup... 493 e-139
YEL065w [R] KOG0254 Predicted transporter (major facilitator sup... 414 e-115
YOL158c [R] KOG0254 Predicted transporter (major facilitator sup... 256 9e-68
SPBC4F6.09 [R] KOG0254 Predicted transporter (major facilitator ... 225 2e-58
SPCC61.01c [R] KOG0254 Predicted transporter (major facilitator ... 144 5e-34
SPAC1F8.03c [R] KOG0254 Predicted transporter (major facilitator... 134 5e-31
YPR198w [R] KOG0254 Predicted transporter (major facilitator sup... 60 8e-09
>YHL047c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 637
Score = 737 bits (1903), Expect = 0.0
Identities = 344/589 (58%), Positives = 443/589 (74%), Gaps = 3/589 (0%)
Query: 31 EMDEDSKKGVQFSGVCDGMKQTKSLVIRKTEIMASQYNTWYSQVLFLSCAFLCAYGYSLD 90
+MD+DS + D +K TKSL+IRK+E+MA +Y+TW + +FL AF+C + Y LD
Sbjct: 30 KMDDDSSPRDEMK---DKLKGTKSLIIRKSELMAKKYDTWQLKAIFLFSAFICTFAYGLD 86
Query: 91 SSIRYVYMTYATNSYNTHSLLSTISIINMMISAVAQLFFAGLSDVFGRLRLMIVAILFYV 150
SSIR YMTYA NSY+ HSL+ST+S+I +MISAV+Q+ F GLSD+FGRL L +V+I+ Y+
Sbjct: 87 SSIRGTYMTYAMNSYSAHSLISTVSVIVLMISAVSQVIFGGLSDIFGRLTLFLVSIVLYI 146
Query: 151 VGTVIQSQAYDIQRYAAGSVFYNIGVVGVMLQVSLFLADNSSLKWRLLYSFVPAWPAIIN 210
VGT+IQSQAYD+QRYAAG+VFY +G+VGVMLQV L L+DNSSLKWRL Y+ +P+WP+II
Sbjct: 147 VGTIIQSQAYDVQRYAAGAVFYYVGLVGVMLQVVLMLSDNSSLKWRLFYTLIPSWPSIIT 206
Query: 211 MWVSGNIVKAANPLVNWSWNIAMWAFIXXXXXXXXXXXXXHMRWKASKTPEWQELESELT 270
WVSG++V+AANPL NWSWNIAMWAFI HMRWK EW+EL+ E +
Sbjct: 207 TWVSGSVVEAANPLENWSWNIAMWAFIFPLCCIPLILCMLHMRWKVRNDVEWKELQDEKS 266
Query: 271 FYQKHGFVHTIVEVFWKVDIVGLLLLTASMGCILVPLTIAGGISEQWNNGKIIXXXXXXX 330
+YQ HG V +V++FWK+D+VG+LL TA +GCILVPLT+AGG+S W N KII
Sbjct: 267 YYQTHGLVQMLVQLFWKLDVVGVLLFTAGVGCILVPLTLAGGVSTNWRNSKIIGPFVLGF 326
Query: 331 XXXXXTIYWESNWAKVPFAPFLLLKDRGIWAPMSIMFLVCFIYQMAAGYLYTILLVSMNQ 390
IYWES A VPFAPF LLKDRG+WAP+ IMF +CF+YQMAAGYLYTIL+V++++
Sbjct: 327 VLVPGFIYWESRLALVPFAPFKLLKDRGVWAPLGIMFFICFVYQMAAGYLYTILVVAVDE 386
Query: 391 TELSATRIMNLYSFVAGIYSPIFGFVVARTGRLKSFMLVGCCLYFLVMGLFYRYRGGLGA 450
+ SATRI+NLYSFV + +P G +V R+ RLKS+++ G LYF+ MGLFYRYR G A
Sbjct: 387 SASSATRIINLYSFVTAVVAPFLGLIVTRSSRLKSYIIFGGSLYFITMGLFYRYRSGQDA 446
Query: 451 ESGIIGAMVVWGIASCMYTYPVTTSAQSVTSHENMATVTAMLLTIFRIXXXXXXXXXXXI 510
+ GII MV+WG++SC++ YP S QSVTSHENMATVTA+ T+FRI I
Sbjct: 447 DGGIIAGMVIWGLSSCLFDYPTIVSIQSVTSHENMATVTALNYTVFRIGGAVAAAISGAI 506
Query: 511 WTNLLYPKLLQNLGDVELASAAYTAPLTFIVSHPWNTEVRTAMIDAYRHVQKYEVLVGLI 570
WT LYPKLL +GD +LA+AAY +PLTFI+S+PW T VR+AM++AYRHVQKYEV+V L+
Sbjct: 507 WTQSLYPKLLHYMGDADLATAAYGSPLTFILSNPWGTPVRSAMVEAYRHVQKYEVIVALV 566
Query: 571 FVAPMLVLTFCLRDPELTDDYGQKLAEGQCVQTEGEDPIAEWFSDRFKK 619
F APM +LTFC+RDP LT+D+ QKL + + VQT+ +DPI +W + RF K
Sbjct: 567 FSAPMFLLTFCVRDPRLTEDFAQKLPDREYVQTKEDDPINDWIAKRFAK 615
>YHL040c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 627
Score = 632 bits (1630), Expect = 0.0
Identities = 296/614 (48%), Positives = 417/614 (67%), Gaps = 3/614 (0%)
Query: 1 MHNNPVLKMENDQIEDGVGHRKEGAAEKINEMDEDSKKGVQFSGVCDGMKQTKSLVIRKT 60
+H+ +K E + G+ H E E N+ + DS Q S + ++Q +SL+I++T
Sbjct: 4 VHSRDPVKEEKKHVFMGMEH--ELNPETHNDSNSDSYGLPQLSEKYNALRQNRSLIIQQT 61
Query: 61 EIMASQYNTWYSQVLFLSCAFLCAYGYSLDSSIRYVYMTYATNSYNTHSLLSTISIINMM 120
EI+ S YN WY Q + L AF+C YGY LD +IRY+Y YAT+SY+ HSLLSTI++IN +
Sbjct: 62 EIIGSAYNKWYLQAILLLSAFICGYGYGLDGNIRYIYTGYATSSYSEHSLLSTINVINAV 121
Query: 121 ISAVAQLFFAGLSDVFGRLRLMIVAILFYVVGTVIQSQAYDIQRYAAGSVFYNIGVVGVM 180
+SA +Q+ +A LSDVFGRL L I A++ YVVGT+IQSQAYD+QRYAAG++FYN G VGV+
Sbjct: 122 VSAASQIIYARLSDVFGRLYLFISAVILYVVGTIIQSQAYDVQRYAAGAIFYNAGYVGVI 181
Query: 181 LQVSLFLADNSSLKWRLLYSFVPAWPAIINMWVSGNIVKAANPLVNWSWNIAMWAFIXXX 240
L + + L+D SSLKWRLLY FVP WP IIN W++GNI ANP+VNWSW++ MWAFI
Sbjct: 182 LILLIILSDFSSLKWRLLYQFVPTWPFIINTWIAGNITSRANPVVNWSWDVGMWAFIFPL 241
Query: 241 XXXXXXXXXXHMRWKASKTPEWQELESELTFYQKHGFVHTIVEVFWKVDIVGLLLLTASM 300
HM+W+A KTPEW L+ + ++YQ+HGF+ + ++FW +D+VG+LL+ S+
Sbjct: 242 SCVPIVLCMLHMQWRARKTPEWHALKGQKSYYQEHGFIKILKQLFWMLDVVGVLLMGCSL 301
Query: 301 GCILVPLTIAGGISEQWNNGKIIXXXXXXXXXXXXTIYWESNWAKVPFAPFLLLKDRGIW 360
GCILVPLT+AGG+ WN+ ++I WE +A+ P P+ L+KDR +W
Sbjct: 302 GCILVPLTLAGGVKTTWNDSRLIGPFVLGFVLIPILWIWEYRFARDPILPYRLVKDRAVW 361
Query: 361 APMSIMFLVCFIYQMAAGYLYTILLVSMNQTELSATRIMNLYSFVAGIYSPIFGFVVART 420
+ M I FL+ FIY MAA YLYT+++V++N++ SATRI L SFV+ + SP F +V R
Sbjct: 362 SSMGISFLIDFIYYMAADYLYTVMIVAVNESVKSATRIATLSSFVSTVASPFFALLVTRC 421
Query: 421 GRLKSFMLVGCCLYFLVMGLFYRYRGGLGAESGIIGAMVVWGIASCMYTYPVTTSAQSVT 480
RLK F++ GC L+ + MGL Y +RGG + SGIIGA+ VWG+ + ++TYPVT S QS
Sbjct: 422 TRLKPFIMFGCALWMVAMGLLYHFRGGSQSHSGIIGALCVWGVGTTLFTYPVTVSVQSAV 481
Query: 481 SHENMATVTAMLLTIFRIXXXXXXXXXXXIWTNLLYPKLLQNLGDVELASAAYTAPLTFI 540
SHENMATVTA+ T++RI IWT LY ++L+ +GDV LA+ AY +P TFI
Sbjct: 482 SHENMATVTALNYTLYRIGSAVGSAVSGAIWTQTLYKQILKRMGDVALATTAYESPYTFI 541
Query: 541 VSHPWNTEVRTAMIDAYRHVQKYEVLVGLIFVAPMLVLTFCLRDPELTDDYG-QKLAEGQ 599
++ W T R A+++AY++VQ+ E +V L+F P++ + CLRDP+LTD + + +G+
Sbjct: 542 ETYTWGTPQRNALMNAYKYVQRLETIVALVFCVPLIAFSLCLRDPKLTDTVAVEYIEDGE 601
Query: 600 CVQTEGEDPIAEWF 613
V T+ DPI +WF
Sbjct: 602 YVDTKDNDPILDWF 615
>YCL073c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 615
Score = 494 bits (1273), Expect = e-139
Identities = 237/533 (44%), Positives = 342/533 (63%)
Query: 57 IRKTEIMASQYNTWYSQVLFLSCAFLCAYGYSLDSSIRYVYMTYATNSYNTHSLLSTISI 116
+++ EIM++Q+++ ++L +S AF+C +G SLD ++R Y YATNSY+ HSLLST+ +
Sbjct: 43 LKENEIMSAQFDSLKYKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQV 102
Query: 117 INMMISAVAQLFFAGLSDVFGRLRLMIVAILFYVVGTVIQSQAYDIQRYAAGSVFYNIGV 176
IN ++S +Q+ ++ LSD FGRLRL +VA +FY++GT+IQSQA + YAAGSVFYN G
Sbjct: 103 INAVVSVGSQVVYSRLSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGY 162
Query: 177 VGVMLQVSLFLADNSSLKWRLLYSFVPAWPAIINMWVSGNIVKAANPLVNWSWNIAMWAF 236
VG L ++L L+D SSLKWR+ Y + WP II W+SGNI+ AANP NWSWNIAMWAF
Sbjct: 163 VGTNLLLTLILSDFSSLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAF 222
Query: 237 IXXXXXXXXXXXXXHMRWKASKTPEWQELESELTFYQKHGFVHTIVEVFWKVDIVGLLLL 296
I +M++K+SKT EW+ L+ + + G +V +FWK+DIVG+LL+
Sbjct: 223 IYPLSALPIIFLILYMKYKSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDIVGILLI 282
Query: 297 TASMGCILVPLTIAGGISEQWNNGKIIXXXXXXXXXXXXTIYWESNWAKVPFAPFLLLKD 356
T S+GCILVPLT+A S++W+N KII +YWE+ +AK P PF LL D
Sbjct: 283 TVSLGCILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAKSPLLPFKLLSD 342
Query: 357 RGIWAPMSIMFLVCFIYQMAAGYLYTILLVSMNQTELSATRIMNLYSFVAGIYSPIFGFV 416
RGIWAP+ + F F + ++ YLY +LLVSM ++ SA RI+NL FVA SP + +
Sbjct: 343 RGIWAPLGVTFFNFFTFFISCDYLYPVLLVSMKESSTSAARIVNLPDFVAATASPFYSLL 402
Query: 417 VARTGRLKSFMLVGCCLYFLVMGLFYRYRGGLGAESGIIGAMVVWGIASCMYTYPVTTSA 476
VA+T +LK ++ GC + + MGLFY+YRGG G+ G+I A V+ G++ + + V
Sbjct: 403 VAKTRKLKLSVIGGCAAWMVCMGLFYKYRGGSGSHEGVIAASVIMGLSGLLCSNSVIVIL 462
Query: 477 QSVTSHENMATVTAMLLTIFRIXXXXXXXXXXXIWTNLLYPKLLQNLGDVELASAAYTAP 536
Q++T+H MA +T + T ++ IWT + +L +NLG+ LA AY +P
Sbjct: 463 QAMTTHSRMAVITGIQYTFSKLGAAIGASVSGAIWTQTMPNQLYKNLGNDTLAEIAYASP 522
Query: 537 LTFIVSHPWNTEVRTAMIDAYRHVQKYEVLVGLIFVAPMLVLTFCLRDPELTD 589
TFI +PW + R A++++YR+VQ+ + VGL P T +RDPEL D
Sbjct: 523 YTFISDYPWGSPERDAVVESYRYVQRIIMTVGLACTVPFFAFTMFMRDPELID 575
>YKR106w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 615
Score = 493 bits (1268), Expect = e-139
Identities = 236/533 (44%), Positives = 342/533 (63%)
Query: 57 IRKTEIMASQYNTWYSQVLFLSCAFLCAYGYSLDSSIRYVYMTYATNSYNTHSLLSTISI 116
+++ EIM++Q+++ ++L +S AF+C +G SLD ++R Y YATNSY+ HSLLST+ +
Sbjct: 43 LKENEIMSAQFDSLKYKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQV 102
Query: 117 INMMISAVAQLFFAGLSDVFGRLRLMIVAILFYVVGTVIQSQAYDIQRYAAGSVFYNIGV 176
IN ++S +Q+ ++ LSD FGRLRL +VA +FY++GT+IQSQA + YAAGSVFYN G
Sbjct: 103 INAVVSVGSQVVYSRLSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGY 162
Query: 177 VGVMLQVSLFLADNSSLKWRLLYSFVPAWPAIINMWVSGNIVKAANPLVNWSWNIAMWAF 236
VG L ++L L+D SSLKWR+ Y + WP II W+SGNI+ AANP NWSWNIAMWAF
Sbjct: 163 VGTNLLLTLILSDFSSLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAF 222
Query: 237 IXXXXXXXXXXXXXHMRWKASKTPEWQELESELTFYQKHGFVHTIVEVFWKVDIVGLLLL 296
I +M++K+SKT EW+ L+ + + G +V +FWK+DIVG+LL+
Sbjct: 223 IYPLSTLPIIFLILYMKYKSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDIVGILLI 282
Query: 297 TASMGCILVPLTIAGGISEQWNNGKIIXXXXXXXXXXXXTIYWESNWAKVPFAPFLLLKD 356
T S+GCILVPLT+A S++W+N KII +YWE+ +AK P PF LL D
Sbjct: 283 TVSLGCILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAKSPLLPFKLLSD 342
Query: 357 RGIWAPMSIMFLVCFIYQMAAGYLYTILLVSMNQTELSATRIMNLYSFVAGIYSPIFGFV 416
RGIWAP+ + F F + ++ YLY +LLVSM ++ SA RI+NL FVA SP + +
Sbjct: 343 RGIWAPLGVTFFNFFTFFISCDYLYPVLLVSMKESSTSAARIVNLPDFVAATASPFYSLL 402
Query: 417 VARTGRLKSFMLVGCCLYFLVMGLFYRYRGGLGAESGIIGAMVVWGIASCMYTYPVTTSA 476
VA+T +LK ++ GC + + MGLFY+YRGG G+ G+I A V+ G++ + + V
Sbjct: 403 VAKTRKLKLSVIGGCAAWMVCMGLFYKYRGGSGSHEGVIAASVIMGLSGLLCSNSVIVIL 462
Query: 477 QSVTSHENMATVTAMLLTIFRIXXXXXXXXXXXIWTNLLYPKLLQNLGDVELASAAYTAP 536
Q++T+H MA +T + T ++ IWT + +L +NLG+ LA AY +P
Sbjct: 463 QAMTTHSRMAVITGIQYTFSKLGAAIGASVSGAIWTQTMPNQLYKNLGNDTLAEIAYASP 522
Query: 537 LTFIVSHPWNTEVRTAMIDAYRHVQKYEVLVGLIFVAPMLVLTFCLRDPELTD 589
TFI +PW + R A++++YR+VQ+ + VGL P T +R+PEL D
Sbjct: 523 YTFISDYPWGSPERDAVVESYRYVQRIIMTVGLACTVPFFTFTMFMRNPELID 575
>YEL065w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 628
Score = 414 bits (1064), Expect = e-115
Identities = 214/536 (39%), Positives = 318/536 (58%), Gaps = 6/536 (1%)
Query: 57 IRKTEIMASQYNTWYSQVLFLSCAFLCAYGYSLDSSIRYVYMTYATNSYNTHSLLSTISI 116
+ EI A YN +V FL AY Y LD +IRY + YAT+SY+ HSLLST++
Sbjct: 54 VHNIEIYAEMYNRPIYRVALFFSLFLIAYAYGLDGNIRYTFQAYATSSYSQHSLLSTVNC 113
Query: 117 INMMISAVAQLFFAGLSDVFGRLRLMIVAILFYVVGTVIQSQAYDIQRYAAGSVFYNIGV 176
I +I+AV Q+FFA LSD+FGR +MIV+I+FY +GT+I+SQA +I R+A G FY +G+
Sbjct: 114 IKTVIAAVGQIFFARLSDIFGRFSIMIVSIIFYSMGTIIESQAVNITRFAVGGCFYQLGL 173
Query: 177 VGVMLQVSLFLADNSSLKWRLLYSFVPAWPAIINMWVSGNIVKAANPLVNWSWNIAMWAF 236
G++L + + +D S+L WRLL F+PA P IIN W+SGN+ A + NW W I MWAF
Sbjct: 174 TGIILILEVIASDFSNLNWRLLALFIPALPFIINTWISGNVTSAID--ANWKWGIGMWAF 231
Query: 237 IXXXXXXXXXXXXXHMRWKASKTPEWQELESELTFYQKHGFVHTIVEV-FWKVDIVGLLL 295
I HMR+ A K + L+ E K + +++ FWK+DI+G+LL
Sbjct: 232 ILPLACIPLGICMLHMRYLARKHAK-DRLKPEFEALNKLKWKSFCIDIAFWKLDIIGMLL 290
Query: 296 LTASMGCILVPLTIAGGISEQWNNGKIIX-XXXXXXXXXXXTIYWESNWAKVPFAPFLLL 354
+T GC+LVP T+AGG+ E+W II + WE +++ P P+ L+
Sbjct: 291 ITVFFGCVLVPFTLAGGLKEEWKTAHIIVPEVIGWVVVLPLYMLWEIKYSRHPLTPWDLI 350
Query: 355 KDRGIWAPMSIMFLVCFIYQMAAGYLYTILLVSMNQTELSATRIMNLYSFVAGIYSPIFG 414
+DRGI+ + I F + F + M Y+YT+L+V+++++ SATRI +LYSFV+ I I G
Sbjct: 351 QDRGIFFALLIAFFINFNWYMQGDYMYTVLVVAVHESIKSATRITSLYSFVSVIVGTILG 410
Query: 415 FVVARTGRLKSFMLVGCCLYFLVMGLFYRYRGGLGAESGIIGAMVVWGIASCMYTYPVTT 474
F++ + R K F++ G + + GL YRG GA SGIIG++ + G + +TY
Sbjct: 411 FILIKVRRTKPFIIFGISCWIVSFGLLVHYRGDSGAHSGIIGSLCLLGFGAGSFTYVTQA 470
Query: 475 SAQ-SVTSHENMATVTAMLLTIFRIXXXXXXXXXXXIWTNLLYPKLLQNLGDVELASAAY 533
S Q S +H MA VT++ L + I +WTN+L ++ + + D LA+ AY
Sbjct: 471 SIQASAKTHARMAVVTSLYLATYNIGSAFGSSVSGAVWTNILPKEISKRISDPTLAAQAY 530
Query: 534 TAPLTFIVSHPWNTEVRTAMIDAYRHVQKYEVLVGLIFVAPMLVLTFCLRDPELTD 589
+P TFI ++ W T R A++ +YR+VQK ++GL+F P+L F LR+ +LTD
Sbjct: 531 GSPFTFITTYTWGTPERIALVMSYRYVQKILCIIGLVFCFPLLGCAFMLRNHKLTD 586
>YOL158c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 606
Score = 256 bits (653), Expect = 9e-68
Identities = 161/517 (31%), Positives = 250/517 (48%), Gaps = 21/517 (4%)
Query: 77 LSCAFLCAYGYSLDSSIRYVYMTYATNSYNTHSLLSTISIINMMISAVAQLFFAGLSDVF 136
L FL Y L I TYA NS+ HS + +I+ + ++++V + +A +SD F
Sbjct: 67 LVALFLQGYCTGLGGQISQSIQTYAANSFGKHSQVGSINTVKSIVASVVAVPYARISDRF 126
Query: 137 GRLRLMIVAILFYVVGTVIQSQAYDIQRYAAGSVFYNIGVVGVMLQVSLFLADNSSLKWR 196
GR+ I A++ Y +G +I + AG V G G L + D S L+ R
Sbjct: 127 GRIECWIFALVLYTIGEIISAATPTFSGLFAGIVIQQFGYSGFRLLATALTGDLSGLRDR 186
Query: 197 LLYSFVPAWPAIINMWVSGNIVKAANPLV---NWSWNIAMWAFIXXXXXXXXXX---XXX 250
+ P IIN WVSGNIV + V W W ++ I
Sbjct: 187 TFAMNIFLIPVIINTWVSGNIVSSVAGNVAPYKWRWGYGIFCIIVPISTLILVLPYVYAQ 246
Query: 251 HMRWKASKTPEWQELESELTFYQKHGFVHTIVEVFWK----VDIVGLLLLTASMGCILVP 306
++ W++ K P + E T Q WK ++++G++L TA + +L+P
Sbjct: 247 YISWRSGKLPPLKLKEKGQTLRQ----------TLWKFADDINLIGVILFTAFLVLVLLP 296
Query: 307 LTIAGGISEQWNNGKIIXXXXXXXXXXXXTIYWESNWAKVPFAPFLLLKDRGIWAPMSIM 366
LTIAGG + +W G II + WE +AK PF P + L D I+ + +
Sbjct: 297 LTIAGGATSKWREGHIIAMIVVGGCLGFIFLIWELKFAKNPFIPRVYLGDPTIYVALLME 356
Query: 367 FLVCFIYQMAAGYLYTILLVSMNQTELSATRIMNLYSFVAGIYSPIFGFVVARTGRLKSF 426
F+ Q+ YL T+L+V+ ++ LSA RI LY+F+ + + G ++ K F
Sbjct: 357 FVWRLGLQIELEYLVTVLMVAFGESTLSAQRIAQLYNFLQSCTNIVVGIMLHFYPHPKVF 416
Query: 427 MLVGCCLYFLVMGLFYRYRGGLGAESGIIGAMVVWGIASCMYTYPVTTSAQSVTSHENMA 486
++ G L + MGL Y+YR SG+IGA +V GIA M +P+ T + T+H MA
Sbjct: 417 VVAGSLLGVIGMGLLYKYRVVYDGISGLIGAEIVVGIAGGMIRFPMWTLVHASTTHNEMA 476
Query: 487 TVTAMLLTIFRIXXXXXXXXXXXIWTNLLYPKLLQNLGDVELASAAYTAPLTFIVSHPWN 546
TVT +L+++++I IWT L +L+Q LG L A Y +PL ++ +P
Sbjct: 477 TVTGLLMSVYQIGDAVGASIAGAIWTQRLAKELIQRLGS-SLGMAIYKSPLNYLKKYPIG 535
Query: 547 TEVRTAMIDAYRHVQKYEVLVGLIFVAPMLVLTFCLR 583
+EVR MI++Y +Q+ ++V + F A VL F LR
Sbjct: 536 SEVRVQMIESYSKIQRLLIIVSISFAAFNAVLCFFLR 572
>SPBC4F6.09 [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 612
Score = 225 bits (573), Expect = 2e-58
Identities = 163/590 (27%), Positives = 276/590 (46%), Gaps = 25/590 (4%)
Query: 10 ENDQIEDGVGHRKEGAAEKINEMDEDSKKGVQ---FSGVCDGMKQTKSLVIRKTEIMASQ 66
E D++E + + + + +KGV+ F+ + + I+ ++
Sbjct: 23 EEDKLEKNIQDETSIKEVSLQDAKQSDEKGVEEKVFNDESFSIDVAPKPEDELSGIVKAR 82
Query: 67 YNTWYS-QVLFLSC---AFLCAYGYSLDSSIRYVYMTYATNSYNTHSLLSTISIINMMIS 122
Y T +S ++ F C FL + S + Y YAT+++ HSLLSTI++ N +IS
Sbjct: 83 YLTEHSSRISFYICYFSIFLLFFAISFQAECYYSLTAYATSAFAGHSLLSTIAVANNIIS 142
Query: 123 AVAQLFFAGLSDVFGRLRLMIVAILFYVVGTVIQSQAYDIQRYAAGSVFYNIGVVGVMLQ 182
A + A LSDVFGRL + ++L Y+VG ++ + + ++Q YA GSV YN G GV L
Sbjct: 143 AAIKPPLARLSDVFGRLEAFLFSLLLYLVGLILMAASTNVQTYAGGSVLYNAGYTGVELI 202
Query: 183 VSLFLADNSSLKWRLLYSFVPAWPAIINMWVSGNIVKAANPLVNWSWNIAMWAFIXXXXX 242
+++F+AD SS+ R L + P ++ +W+ + + W W IA+W +
Sbjct: 203 MTIFMADTSSMANRSLVLGISYLPFVVTIWIGPRVAQEFYMHSTWRWGIAVWTILIPACS 262
Query: 243 XXXXXXXXHMRWKASKTPEWQE--LESELTFYQKHGFVHTIVEVFWKVDIVGLLLLTASM 300
+ +++A W+E L+ LT VE+F K+DI+GL+L+TA +
Sbjct: 263 IPFLAVYSYYQFRA-----WREGALKGTLTI--------NPVELFKKLDIIGLILMTAGL 309
Query: 301 GCILVPLTIAGGISEQWNNGKIIXXXXXXXXXXXXTIYWESNWAKVPFAPFLLLKDRGIW 360
+L+ +++A + +W++ K I + +E A P PF L+++ I
Sbjct: 310 ALVLLSISLASYDTGKWSDAKFIVMIIIGGLCLIAFVLYEIFVASFPALPFRLMREPTIG 369
Query: 361 APMSIMFLVCFIYQMAAGYLYTILLVSMNQTELSATRIMNLYSFVAGIYSPIFGFVVART 420
A ++ FL + Y Y+ L V + +A I YSF + G ++ T
Sbjct: 370 ACCAMSFLFYITFYCWDNYYYSFLQVVHYTSITAAGYISYTYSFTSCATGFFLGILIRLT 429
Query: 421 GRLKSFMLVGCCLYFLVMGLFYRYRGGLGAESGIIGAMVVWGIASCMYTYPVTTSAQSVT 480
R K + + +Y L GL RYRG I ++ GI + +T + Q+V
Sbjct: 430 KRYKWYFVASIPVYILGQGLMIRYRGEQYNWGYQIMPQIIVGIGGGVIANLLTVAVQTVV 489
Query: 481 SHENMATVTAMLLTIFRIXXXXXXXXXXXIWTNLLYPKLLQNLGDVELASAAYT--APLT 538
S EN A VTA++ T+ I IW +++ +L +NL +L AYT LT
Sbjct: 490 STENFAIVTALVSTVTPIGGAVGSAISGAIWNSVMPKRLEKNLPS-DLKDQAYTIFESLT 548
Query: 539 FIVSHPWNTEVRTAMIDAYRHVQKYEVLVGLIFVAPMLVLTFCLRDPELT 588
+S+ T+ R A+I +Y VQK V F M+ + + +P L+
Sbjct: 549 VQLSYTRGTDARNAIILSYSEVQKILTSVATGFAGAMIFPVWFVANPRLS 598
>SPCC61.01c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 597
Score = 144 bits (362), Expect = 5e-34
Identities = 117/542 (21%), Positives = 237/542 (43%), Gaps = 13/542 (2%)
Query: 57 IRKTEIMASQYNTWYSQVLFLSCAFLCAYGYSLDSSIRYVYMTYATNSYNTHSLLSTISI 116
+ K E +AS ++ V +L +L ++ SL+ Y YAT++++ HS L+TI++
Sbjct: 50 VSKAEAIASTWSKRSIIVAYLGL-YLLSFASSLEQQTTYSLQRYATSNFSAHSNLATINL 108
Query: 117 INMMISAVAQLFFAGLSDVFGRLRLMIVAILFYVVGTVIQSQAYDIQRYAAGSVFYNIGV 176
+ ++ AV + +DVFGR + +A+ V+G + + + +IQ + + Y G
Sbjct: 109 VGNILLAVVRAPMVKAADVFGRSESLSLALGMTVLGYLSLAFSRNIQMFTVAYILYICGQ 168
Query: 177 VGVMLQVSLFLADNSSLKWRLLYSFVPAWPAIINMWVSGNIVKAANPLVNWSWNI--AMW 234
G+ L L +AD SSL R + S +P P + +W+ + +A +P N+ W + +W
Sbjct: 169 TGLGLLSQLIIADTSSLLNRGILSAIPELPYLATVWIGPVLAQAFHPEKNYGWRLGYGIW 228
Query: 235 AFIXXXXXXXXXXXXXHMRWKASKTPEWQELESELTFYQKHGFVHTIVEVFW-KVDIVGL 293
AFI + KA ++E + + + +FW ++D +G+
Sbjct: 229 AFILPTVSLPLLASLFLNQRKAKAAGLYREHHNLINHSTPEKL--RLFYLFWQELDGLGI 286
Query: 294 LLLTASMGCILVPLTIAGGISEQWNNGKIIXXXXXXXXXXXXTIYWESNWAKVPFAPFLL 353
+L + +L+P + + + + + +++ +A+ P
Sbjct: 287 VLFVSGFTLLLLPFSHSSQVVSPDSTILTLFTITLSIALLVTLCFYDVKYARYPVFALKS 346
Query: 354 LKDRGIWAPMSIMFLVCFIYQMAAGYLYTILLVSMNQTELSATRIMNLYSFVAGIYSPIF 413
LKDR I ++F Y + + +L + L VS + ++ +N++ F + +
Sbjct: 347 LKDRTILGSCVLIFTYFMSYYIFSNFLTSFLQVSYGLSIDMSSLTLNVFVFSMTTTAILS 406
Query: 414 GFVVARTGRLKSFMLVGCCLYFL-VMGLFYRYRGGLGAESGIIGAMVVWGIASCMYTYPV 472
GF++ R GR K +++ +Y L ++G+ ++ +++ G+ + T
Sbjct: 407 GFLMKRFGRFKMLLMISVPMYVLGILGIILFGINDNHYTRPLVLVLILAGMGGGLLTLSA 466
Query: 473 TTSAQSVTSHENMATVTAMLLTIFRIXXXXXXXXXXXIWTNLLYPKLLQNLGD----VEL 528
+ QSV+SH + + LT + +W+ L +LL +L D E+
Sbjct: 467 QIAVQSVSSHAKLGMNLTLYLTFSSVGGAFGSAIAGGVWSKRLSSRLLHDLKDHLPVPEI 526
Query: 529 ASAAYTAPLTFIVSHPWNTEVRTAMIDAYRHVQKYEVLVGLIFVAPMLVLTFCLRDPELT 588
S L +S+P T++R + AY +K + L+ M +RD L+
Sbjct: 527 ES--IFRDLRTALSYPQGTQIRNIINVAYTATEKDLFHISLVASLFMFAGLVIIRDVPLS 584
Query: 589 DD 590
+
Sbjct: 585 TE 586
>SPAC1F8.03c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 630
Score = 134 bits (336), Expect = 5e-31
Identities = 117/504 (23%), Positives = 216/504 (42%), Gaps = 34/504 (6%)
Query: 75 LFLSCAF-----LCAYGYSLDSSIRYVYMTYATNSYNTHSLLSTISIINMMISAVAQLFF 129
++L+ AF C++ ++ SS Y Y YAT S+N S++ST+ I +IS+V +
Sbjct: 81 MYLAYAFGIAILACSWASAIQSSTTYSYQVYATASFNRTSMISTLEIATAIISSVCKPIL 140
Query: 130 AGLSDVFGRLRLMIVAILFYVVGTVIQSQAYDIQRYAAGSVFYNIGVVGVMLQVSLFLAD 189
SD+ R + +LFYV+G ++ + + I Y GSVF +IG G+ +L + D
Sbjct: 141 GKFSDITSRPMTYTLVLLFYVIGFIVVASSSTISAYVIGSVFISIGSSGLDYLNTLVVGD 200
Query: 190 NSSLKWRLLYSFVPAWPAIINMWVSGNIVKAANPLVNWSWNIAMWAFIXXXXXXXXXXXX 249
+SLKWR + + + P I +W +G IV+ NW W M+A I
Sbjct: 201 LTSLKWRGFMTALLSTPYIATVWFTGFIVQGIID-SNWRWGYGMFAIIMPAVMTPAVIIL 259
Query: 250 XHMRWKASKTPEWQELESELTFYQKHGFVHTIVEVFWK----VDIVGLLLLTASMGCILV 305
++ +A+K +++ + T +K+ + + WK VD+ GL+LL +L+
Sbjct: 260 MYLERQANKDENIKKIINYQT-EEKNKNKQSKWQKLWKAVLEVDLFGLILLGVGWSILLL 318
Query: 306 PLTIAGGISEQWNNGKIIXXXXXXXXXXXXTIYWESNWAKVPFAPFLLLKDRGIWAPMSI 365
P ++ W N +I +E A P P ++ I A
Sbjct: 319 PFSLTSYAKNGWKNPSMIAMMVVGGVILIAYSGYEMFIAPYPSCPRRVMNRTFITA---- 374
Query: 366 MFLVCFIYQMAAGYL-------YTILLVSMNQTELSATRIMNLYSFVAGIYSPIFGFVVA 418
++ F Y + AGYL YT +L + + T N + ++ G +
Sbjct: 375 -VIIDFFYYL-AGYLQSMYFTTYTWILYDWSYRDW--TYFNNTMTIALCVFGVFAGAMHR 430
Query: 419 RTGRLKSFMLVGCCLYFLVMGLFYRYRGGLGAESGIIGAMVVWGIASCMYTYPVTTSAQS 478
R K ++G + + G+ R + + ++++ G+ S Q+
Sbjct: 431 VFHRYKYLQIIGLVIKIVGYGILIRPNFAATGKVDLAWSLILIGMGGSFSVVGSQVSCQA 490
Query: 479 VTSHENMATVTAMLLTIFRIXXXXXXXXXXXIWTNLLYPKLLQ-----NLGDVELASAAY 533
H+++A +++L I I++N + PK L+ ++ D ++ + +
Sbjct: 491 SVPHQDLAIASSLLPLYTNIGGAIGAAIASPIFSNKV-PKYLREYLPSSINDTQVYN--F 547
Query: 534 TAPLTFIVSHPWNTEVRTAMIDAY 557
+ + I +P TE+R I AY
Sbjct: 548 YSDSSLIREYPVGTEIRDGAIKAY 571
>YPR198w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 543
Score = 60.5 bits (145), Expect = 8e-09
Identities = 83/384 (21%), Positives = 162/384 (41%), Gaps = 32/384 (8%)
Query: 122 SAVAQLFFAGLSDVFGRLRLMIVAILFYVVGTVIQSQAYDIQRYAAGSVFYNIGVVGVML 181
+AV L + L+++ G ++++++ + +G++I + + + +G V G G+
Sbjct: 56 NAVFMLLWGRLAEILGTKECLMISVIVFEIGSLISALSNSMATLISGRVVAGFGGSGI-- 113
Query: 182 QVSLFLADNSSLK--WRLLYSFVPAWPAIINMWVSGNIVKAANPLVNWSW----NIAMWA 235
+ F+ S ++ R + A +I V I A N ++W W N+ + A
Sbjct: 114 ESLAFVVGTSIVRENHRGIMITALAISYVIAEGVGPFIGGAFNEHLSWRWCFYINLPIGA 173
Query: 236 FIXXXXXXXXXXXXXHMR-WKASKTPEWQELE-SELTFYQKHGFVHTIVEVF-WKVDIVG 292
F H + W SK + + EL K F EV +K+D+VG
Sbjct: 174 FAFIILAFCNTSGEPHQKMWLPSKIKKIMNYDYGELL---KASFWKNTFEVLVFKLDMVG 230
Query: 293 LLLLTASMGCILVPLTIAGGISEQWNNGKIIXXXXXXXXXXXXTIYWESNWAKV------ 346
++L +A +++ L+ GG + WN+G II ++ ++ +
Sbjct: 231 IILSSAGFTLLMLGLSF-GGNNFPWNSGIIICFFTVGPILLLLFCAYDFHFLSLSGLHYD 289
Query: 347 -----PFAPFLLLKDRGIWAPMSIMFLVCFIYQMAAGYLYTIL-LVSMNQTELSATRIMN 400
P + + + GI+ FL CF Y++ + YL + LV + L++ +
Sbjct: 290 NKRIKPLLTWNIASNCGIFTSSITGFLSCFAYELQSAYLVQLYQLVFKKKPTLASIHLWE 349
Query: 401 LYSFVAGIYSPIFGFVVARTGRLKSFMLVGCCLYFLVMGLFYRYRGGLGAESGIIGAMVV 460
L S A I + ++ ++ G +K ++ G + GLF G L S IG ++
Sbjct: 350 L-SIPAMIATMAIAYLNSKYGIIKPAIVFGVLCGIVGSGLFTLINGEL---SQSIGYSIL 405
Query: 461 WGIA-SCMYTYPVTTSAQSVTSHE 483
GIA ++ + +S +TS +
Sbjct: 406 PGIAFGSIFQATLLSSQVQITSDD 429
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.326 0.138 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,638,380
Number of Sequences: 60738
Number of extensions: 1221636
Number of successful extensions: 3714
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3685
Number of HSP's gapped (non-prelim): 11
length of query: 624
length of database: 30,389,216
effective HSP length: 112
effective length of query: 512
effective length of database: 23,586,560
effective search space: 12076318720
effective search space used: 12076318720
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)