ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0105 good E KOG1250 Amino acid transport and metabolism Threonine/serine dehydratases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0105 33141 32011 -377
(377 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YCL064c [E] KOG1250 Threonine/serine dehydratases 315 9e-86
Hs5803161 [E] KOG1250 Threonine/serine dehydratases 127 2e-29
Hs19923959 [E] KOG1250 Threonine/serine dehydratases 124 2e-28
7299166 [E] KOG1250 Threonine/serine dehydratases 64 4e-10
SPBC1677.03c [E] KOG1250 Threonine/serine dehydratases 58 3e-08
>YCL064c [E] KOG1250 Threonine/serine dehydratases
Length = 360
Score = 315 bits (806), Expect = 9e-86
Identities = 158/326 (48%), Positives = 213/326 (64%), Gaps = 1/326 (0%)
Query: 24 LFSKTPLLKHQFKRSKGPQVLLKYEFLQPSGSFKSRGIGHLISTKVEEIKKSSPEKIGHV 83
+++KTPLL+ F Q LKYE LQPSGSFKSRGIG+LI I+K ++ V
Sbjct: 4 VYNKTPLLRQFFPGKASAQFFLKYECLQPSGSFKSRGIGNLIMKSAIRIQKDG-KRSPQV 62
Query: 84 FXXXXXXXXXXXXXXXXXXNVPCTVVVSNATRPRIIEKIRSYGADVVVHGNHWKEADSFM 143
F ++PCTVVV AT+ R+++KIR+ GA V+V G +WKEAD+F+
Sbjct: 63 FASSGGNAGFAAATACQRLSLPCTVVVPTATKKRMVDKIRNTGAQVIVSGAYWKEADTFL 122
Query: 144 KEHLMKKLDSFKYEPIYSHPFDNPLIWEGHSFMVDEIMDVLASSKIPITKIKGIVCSFXX 203
K ++M K+DS EPIY HPFDNP IWEGHS M+DEI+ L S I + K+KGIVCS
Sbjct: 123 KTNVMNKIDSQVIEPIYVHPFDNPDIWEGHSSMIDEIVQDLKSQHISVNKVKGIVCSVGG 182
Query: 204 XXXXXXXXXXXQRYNLADKIPIVCVETKGTDVLSASLRVGAPVEFEKISSCATSLGTATI 263
+RY LAD+IPIV VET G V + SL++G PV+F+KI+S ATSLGTA I
Sbjct: 183 GGLYNGIIQGLERYGLADRIPIVGVETNGCHVFNTSLKIGQPVQFKKITSIATSLGTAVI 242
Query: 264 STTAYQNVKRHGSKSAVISDTEVISTCLQFSNDTNIVAEPGCGATLYFGYNIDKLQNILG 323
S ++ +++ ++S VI D +VI TCL++++ N+V EP CGA L+ GYN L+N LG
Sbjct: 243 SNQTFEYARKYNTRSVVIEDKDVIETCLKYTHQFNMVIEPACGAALHLGYNTKILENALG 302
Query: 324 SDIKDDDYVILIGCGGSSTSLEDLKE 349
S + DD VI+I CGGSS +++DL+E
Sbjct: 303 SKLAADDIVIIIACGGSSNTIKDLEE 328
>Hs5803161 [E] KOG1250 Threonine/serine dehydratases
Length = 328
Score = 127 bits (320), Expect = 2e-29
Identities = 105/341 (30%), Positives = 147/341 (42%), Gaps = 23/341 (6%)
Query: 24 LFSKTPLLKHQ-FKRSKGPQVLLKYEFLQPSGSFKSRGIGHLISTKVEEIKKSSPEKIGH 82
L KTP+ + G V LK + QPSGSFK RGIGH K+ + + H
Sbjct: 7 LHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFC-------KRWAKQGCAH 59
Query: 83 VFXXXXXXXXXXXXXXXXXXNVPCTVVVSNATRPRIIEKIRSYGADVVVHGNHWKEADSF 142
VP T+VV T IE++++ GA V G EA
Sbjct: 60 FVCSSAGNAGMAAAYAARQLGVPATIVVPGTTPALTIERLKNEGATCKVVGELLDEAFEL 119
Query: 143 MKEHLMKKLDSFKYEPIYSHPFDNPLIWEGHSFMVDEIMDVLASSKIPITKIKGIVCSFX 202
K L K + Y P PFD+PLIWEGH+ +V E+ + L K I S
Sbjct: 120 AKA-LAKNNPGWVYIP----PFDDPLIWEGHASIVKELKETLWE------KPGAIALSVG 168
Query: 203 XXXXXXXXXXXXQRYNLADKIPIVCVETKGTDVLSASLRVGAPVEFEKISSCATSLGTAT 262
Q D +P++ +ET G A+ G V KI+S A +LG T
Sbjct: 169 GGGLLCGVVQGLQECGWGD-VPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKT 227
Query: 263 ISTTAYQNVKRHGSKSAVISDTEVISTCLQFSNDTNIVAEPGCGATL--YFGYNIDKLQN 320
+ + A + + H S VISD E ++ +F +D I+ EP GA L + + I KLQ
Sbjct: 228 VGSQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKILVEPAWGAALAAVYSHVIQKLQ- 286
Query: 321 ILGSDIKDDDYVILIGCGGSSTSLEDLKELSSFTNCEFELP 361
+ G+ +++I CGGS+ SL L+ L LP
Sbjct: 287 LEGNLRTPLPSLVVIVCGGSNISLAQLRALKEQLGMTNRLP 327
>Hs19923959 [E] KOG1250 Threonine/serine dehydratases
Length = 329
Score = 124 bits (311), Expect = 2e-28
Identities = 95/335 (28%), Positives = 155/335 (45%), Gaps = 38/335 (11%)
Query: 28 TPLLKH-QFKRSKGPQVLLKYEFLQPSGSFKSRGIGHLISTKVEEIKKSSPEKIGHVFXX 86
TPLL+ + G V LK E +QPSGSFK RGIGH E KK H+
Sbjct: 18 TPLLESWALSQVAGMPVFLKCENVQPSGSFKIRGIGHFCQ---EMAKKG----CRHLVCS 70
Query: 87 XXXXXXXXXXXXXXXXNVPCTVVVSNATRPRIIEKIRSYGADVVVHGNHWKEADSFMKEH 146
+P T+V+ +T +++++++ GA+V + G W EA+ ++
Sbjct: 71 SGGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEAN--LRAQ 128
Query: 147 LMKKLDSFKYEPIYSHPFDNPLIWEGHSFMVDEIMDVLASSKIPIT-------KIKGIVC 199
+ K D ++ P PFD+PLIW+GH+ +V E+ VL + + + G+V
Sbjct: 129 ELAKRDGWENVP----PFDHPLIWKGHASLVQELKAVLRTPPGALVLAVGGGGLLAGVVA 184
Query: 200 SFXXXXXXXXXXXXXQRYNLADKIPIVCVETKGTDVLSASLRVGAPVEFEKISSCATSLG 259
+PI+ +ET G +A++ G V I+S A SLG
Sbjct: 185 GLLEVGW--------------QHVPIIAMETHGAHCFNAAITAGKLVTLPDITSVAKSLG 230
Query: 260 TATISTTAYQNVKRHGSKSAVISDTEVISTCLQFSNDTNIVAEPGCGATLYFGYN--IDK 317
T++ A + ++ S V+ DTE +S Q +D ++ EP CGA L Y+ + +
Sbjct: 231 AKTVAARALECMQVCKIHSEVVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRR 290
Query: 318 LQNILGSDIKDDDYVILIGCGGSSTSLEDLKELSS 352
LQ G V++I CGG++ + +L+ L +
Sbjct: 291 LQ-AEGCLPPSLTSVVVIVCGGNNINSRELQALKT 324
>7299166 [E] KOG1250 Threonine/serine dehydratases
Length = 469
Score = 63.9 bits (154), Expect = 4e-10
Identities = 68/318 (21%), Positives = 122/318 (37%), Gaps = 36/318 (11%)
Query: 27 KTPLLKHQFKRSKGPQVLLKYEFLQPSGSFKSRGIGHLISTKVEEIKKSSPEKIGHVFXX 86
+TP K G ++ LK +FLQ +GSFK RG + + + EE K++ V
Sbjct: 77 RTPCPKSTSSDLYGMELYLKKDFLQYTGSFKERGARYALLSLTEEQKRTG------VISA 130
Query: 87 XXXXXXXXXXXXXXXXNVPCTVVVSNATRPRIIEKIRSYGADVVVHGNHWKEADSFMKEH 146
N+P TVV+ A I+K R+Y A V+V GN EA S
Sbjct: 131 SLGNHAQALCYHGWKLNIPVTVVMPKAAPIMKIQKCRNYKARVIVDGNDMGEAKSLAMR- 189
Query: 147 LMKKLDSFKYEPIYSHPFDNPLIWEGHSFMVDEIMDVLASSKIPITKI--KGIVCSFXXX 204
M + + +Y + +D+P I G + EI++ + + + G++
Sbjct: 190 -MSREEGL----LYVNGYDHPHIMAGQGTIGLEILEQVPEPDAVVVPVGGGGLIAGIATA 244
Query: 205 XXXXXXXXXXQRYNLADKIPIVCVETKGTDVLSASLRVGAPVEFEKISSCATSLGTATIS 264
L+ K I+ VE++ + ++ P+ ++ A L +
Sbjct: 245 VKA-----------LSPKTKIIGVESEKCASFTRAMENDGPIHTPIKNTLADGLAVPKVG 293
Query: 265 TTAYQNVKRHGSKSAVISDTEVISTCLQFSNDTNIVAE--PGCGATLYFGYNIDKLQNIL 322
AY + V+ + + L+ + V E G G ++D+L+
Sbjct: 294 YNAYATAMPLIDRMVVVKEEWIAVAILRLVEEEKCVVEGAGGAGLAAILAGHLDELKG-- 351
Query: 323 GSDIKDDDYVILIGCGGS 340
V+++ CGG+
Sbjct: 352 -------KKVVVLLCGGN 362
>SPBC1677.03c [E] KOG1250 Threonine/serine dehydratases
Length = 600
Score = 57.8 bits (138), Expect = 3e-08
Identities = 62/282 (21%), Positives = 108/282 (37%), Gaps = 20/282 (7%)
Query: 23 QLFSKTPLLKHQ-FKRSKGPQVLLKYEFLQPSGSFKSRGIGHLISTKVEEIKKSSPEKIG 81
++ +TPL K S G V LK E L P SFK RG + +++ ++ K+
Sbjct: 109 EVIKETPLTKGVVISESTGVPVYLKREDLTPVFSFKIRGAHNKMASLDKQSLKNG----- 163
Query: 82 HVFXXXXXXXXXXXXXXXXXXNVPCTVVVSNATRPRIIEKIRSYGADVVVHGNHWKEADS 141
V V T+V+ T ++ GA+V++HG ++ A
Sbjct: 164 -VIACSAGNHAQGVAYSARTLGVKATIVMPQNTPEIKWRNVKRLGANVLLHGANFDIA-- 220
Query: 142 FMKEHLMKKLDSFKYEPIYSHPFDNPLIWEGHSFMVDEIMDVLASSKIPITKIKGIVCSF 201
K + E I HPFD+P + G + EI+ +I + K+ I C+
Sbjct: 221 --KAECARLAKEQNLEVI--HPFDDPYVIAGQGTIGLEILH-----QIDLRKLDAIYCAV 271
Query: 202 XXXXXXXXXXXXXQRYNLADKIPIVCVETKGTDVLSASLRVGAPVEFEKISSCATSLGTA 261
+R +A + ++ VET D L SL+ V +++ A
Sbjct: 272 GGGGLIAGIATYVKR--IAPHVKVIGVETFDADALKKSLKDKKRVTLKEVGLFADGTAVK 329
Query: 262 TISTTAYQNVKRHGSKSAVISDTEVISTCLQFSNDTNIVAEP 303
+ ++ V ++ ++ E+ + DT V EP
Sbjct: 330 LVGEETFRLVSKNIDDVVLVDKDEICAAIKDVFLDTRSVVEP 371
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.134 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,761,346
Number of Sequences: 60738
Number of extensions: 818120
Number of successful extensions: 1908
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1895
Number of HSP's gapped (non-prelim): 6
length of query: 377
length of database: 30,389,216
effective HSP length: 108
effective length of query: 269
effective length of database: 23,829,512
effective search space: 6410138728
effective search space used: 6410138728
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)