ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0137 good O KOG2089 Posttranslational modification, protein turnover, chaperones Metalloendopeptidase family - saccharolysin & thimet oligopeptidase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0137 42069 44204 712
(712 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YCL057w [O] KOG2089 Metalloendopeptidase family - saccharolysin ... 852 0.0
Hs4507491 [O] KOG2089 Metalloendopeptidase family - saccharolysi... 407 e-113
Hs14149738 [O] KOG2089 Metalloendopeptidase family - saccharolys... 396 e-110
At5g51540 [O] KOG2090 Metalloendopeptidase family - mitochondria... 222 1e-57
At1g67700 [O] KOG2089 Metalloendopeptidase family - saccharolysi... 214 4e-55
At5g65620 [O] KOG2089 Metalloendopeptidase family - saccharolysi... 207 3e-53
At5g10540 [O] KOG2089 Metalloendopeptidase family - saccharolysi... 200 7e-51
7302217 [O] KOG2090 Metalloendopeptidase family - mitochondrial ... 179 1e-44
SPAC1F3.10c [O] KOG2090 Metalloendopeptidase family - mitochondr... 167 5e-41
YKL134c [O] KOG2090 Metalloendopeptidase family - mitochondrial ... 157 7e-38
Hs20548472 [O] KOG2090 Metalloendopeptidase family - mitochondri... 153 1e-36
Hs5174567 [O] KOG2090 Metalloendopeptidase family - mitochondria... 148 2e-35
7301239 [O] KOG2089 Metalloendopeptidase family - saccharolysin ... 121 3e-27
CE28378 [O] KOG2090 Metalloendopeptidase family - mitochondrial ... 86 2e-16
>YCL057w [O] KOG2089 Metalloendopeptidase family - saccharolysin & thimet
oligopeptidase
Length = 712
Score = 852 bits (2200), Expect = 0.0
Identities = 416/692 (60%), Positives = 515/692 (74%), Gaps = 14/692 (2%)
Query: 31 AIRSIMTKTDF-VVPQAAPSWNYTTEELLKQTHEAXXXXXXXXXXXXXXXXPSVENFVTP 89
++ S+ T F + PQA P+W++T ++ +T+E PSV NFV P
Sbjct: 23 SLYSMANTTSFPIAPQAPPNWSFTPSDISGKTNEIINNSNNFYDSMSKVESPSVSNFVEP 82
Query: 90 YLHHENTISPLFNQLTFLQHVSSDKELRDTSTKVTELIENFGIESSLRFKLFRQFDIVWN 149
++ EN + P+ NQLTFLQHVSSDKE+RD S + ++ I+ SLR +F QF VW
Sbjct: 83 FMKFENELGPIINQLTFLQHVSSDKEIRDASVNSSMKLDELNIDLSLRHDIFLQFARVWQ 142
Query: 150 QLKDDAQFKKDHFE--IYKFVEKCHKDFLRSGLNLPEEQRDKVKEIKKKISNNSLQFSKN 207
D Q K D E +K+VEK +KD++ SGL L E R K+KEIKKKIS NS+ FSKN
Sbjct: 143 ----DVQSKADSVERETFKYVEKSYKDYIHSGLELDEGNRLKIKEIKKKISVNSINFSKN 198
Query: 208 LGEQNEFITFTKEELIGVSENVMKQFETVDED---GITKYKVTFKYPDIFPVLKSAKNAE 264
LGEQ E+ITFTKE+L GV ++++ QFET+ D T YKVTFKYPDIFPV+K A +A+
Sbjct: 199 LGEQKEYITFTKEQLEGVPDSILTQFETIKSDKDSNETLYKVTFKYPDIFPVMKLASSAQ 258
Query: 265 TRKRAFIGDQNKVPQNEALFLETLQLRNDLAELLNYDSYADYNLDIKMAKKEEAVLTFLN 324
TRK+AF+ DQNKVP+NEA+ L+TL+LR++LA LL YD+YA+YNL KMA+ V+ FLN
Sbjct: 259 TRKQAFLADQNKVPENEAILLDTLKLRDELASLLGYDTYANYNLYDKMAEDSTTVMNFLN 318
Query: 325 DLKNKLKPXXXXXXXXXXXXXXXXXXXXNTPYDRRYYIWDNRYYDNQYLKKNFQIDEEKI 384
DLK+KL P N D YYIWD+RYYDN+YL +NF +D EKI
Sbjct: 319 DLKDKLIPLGRKELQVLQDMKAEDVKKLNQGADPNYYIWDHRYYDNKYLLENFNVDLEKI 378
Query: 385 AEYFPLESTIKGMLQIYETVLKLKFIE---EDNGDTWHPDVKKLSVWKMDD-NFPSFVGW 440
+EYFPLE+TI GML+IYET+ LKFIE N WH DVK+++VW MDD P+FVGW
Sbjct: 379 SEYFPLEATITGMLEIYETLFNLKFIETKDSQNKSVWHDDVKQIAVWNMDDPKSPNFVGW 438
Query: 441 IYFDLHPREGKYGHAANFGISSSFLKSDGSRSYPVTALVCNFSKPTKDKPALLKHSELTT 500
IYFDLHPR+GKYGHAANFG+SSSF+ D +RSYPVTALVCNFSK TKDKP+LLKH+E+ T
Sbjct: 439 IYFDLHPRDGKYGHAANFGLSSSFMIDDTTRSYPVTALVCNFSKSTKDKPSLLKHNEIVT 498
Query: 501 FFHELGHGIHDLVGGNDIGRFNGPSATPWDFVEAPSQMLEFWTWNKKELKSLSKHYQTEE 560
FFHELGHGIHDLVG N RFNGP + PWDFVEAPSQMLEFWTWNK EL +LS HY+T E
Sbjct: 499 FFHELGHGIHDLVGQNKESRFNGPGSVPWDFVEAPSQMLEFWTWNKNELINLSSHYKTGE 558
Query: 561 KIPDSLLDSLVRTKHINGALFALRQLHFGLFDMKVHTTKDISKLNVTELWNSLREEICLI 620
KIP+SL++SL++TKH+NGALF LRQLHFGLFDMKVHT KD+ L++ + WN LR++I LI
Sbjct: 559 KIPESLINSLIKTKHVNGALFTLRQLHFGLFDMKVHTCKDLQNLSICDTWNQLRQDISLI 618
Query: 621 DNGDIQTKGFNSFGHIMSDSYSAGYYGYMWADVFASDMYYTKFLEDPLNSDVGVQYRDII 680
NG +KG++SFGHIMSDSYSAGYYGY+WA+VFA+DMY+TKF +DPLN+ G+QYRDI+
Sbjct: 619 SNGGTLSKGYDSFGHIMSDSYSAGYYGYLWAEVFATDMYHTKFAKDPLNAKNGIQYRDIV 678
Query: 681 LARGGLYEIEDNLTEFLGRKPNNKAFLKELGL 712
LARGGLY+I DNL EFLGR+P+ AFLKELGL
Sbjct: 679 LARGGLYDINDNLKEFLGREPSKDAFLKELGL 710
>Hs4507491 [O] KOG2089 Metalloendopeptidase family - saccharolysin & thimet
oligopeptidase
Length = 689
Score = 407 bits (1045), Expect = e-113
Identities = 241/618 (38%), Positives = 343/618 (54%), Gaps = 27/618 (4%)
Query: 102 NQLTFLQHVSSDKELRDTSTKVTELIENFGIESSLRFKLFRQFDIVWNQLKDDAQFKKDH 161
N L F QHVS K++R ST+ + + F +E S+R ++++ IVW Q K +KD
Sbjct: 80 NILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQR--IVWLQEK----VQKDS 133
Query: 162 F--EIYKFVEKCHKDFLRSGLNLPEEQRDKVKEIKKKISNNSLQFSKNLGEQNEFITFTK 219
E +++E+ K R+GL+LP E ++ +K IKKK+S + F+KNL E F+ FT
Sbjct: 134 LRPEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTL 193
Query: 220 EELIGVSENVMKQFETVDEDGITKYKVTFKYPDIFPVLKSAKNAETRKRAFIGDQNKVPQ 279
+EL G+ E+ + E + EDG K KVT KYP FP+LK ETR++ + +
Sbjct: 194 QELGGLPEDFLNSLEKM-EDG--KLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKE 250
Query: 280 -NEALFLETLQLRNDLAELLNYDSYADYNLDIKMAKKEEAVLTFLNDLKNKLKPXXXXXX 338
N A+ E + LR + LL + ++ADY L++ MAK + V TFL++L KLKP
Sbjct: 251 ENCAILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQER 310
Query: 339 XXXXXXXXXXXXXXNTPYDRRYYIWDNRYYDNQYLKKNFQIDEEKIAEYFPLESTIKGML 398
P+D R WD RYY NQ + + +D+ + EYFP++ G+L
Sbjct: 311 AVILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLL 370
Query: 399 QIYETVLKLKFIEEDNGDTWHPDVKKLSVWKMDDNFPSFVGWIYFDLHPREGKYGHAANF 458
IY+ +L L F E+ WH DV+ + D VG Y DL+PREGKYGHAA F
Sbjct: 371 GIYQELLGLAFHHEEGASAWHEDVRLYTA--RDAASGEVVGKFYLDLYPREGKYGHAACF 428
Query: 459 GISSSFLKSDGSRSYPVTALVCNFSKPTKDKPALLKHSELTTFFHELGHGIHDLVGGNDI 518
G+ L+ DGSR + A+V NF+KPT D P+LL+H E+ T+FHE GH +H L +
Sbjct: 429 GLQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEF 488
Query: 519 GRFNGPSATPWDFVEAPSQMLEFWTWNKKELKSLSKHYQTEEKIPDSLLDSLVRTKHING 578
F+G + DFVEAPSQMLE W W ++ L +S+HY+T +P LL+ L+ ++ N
Sbjct: 489 AMFSG-THVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANT 547
Query: 579 ALFALRQLHFGLFDMKVHTTKDISKLNVTELWNSLREEICLIDNGDIQTKGFN---SFGH 635
LF LRQ+ D +HT D + E + L +EI G T G N +FGH
Sbjct: 548 GLFNLRQIVLAKVDQALHTQTD---ADPAEEYARLCQEIL----GVPATPGTNMPATFGH 600
Query: 636 IMSDSYSAGYYGYMWADVFASDMYYTKF-LEDPLNSDVGVQYRDIILARGGLYEIEDNLT 694
++ Y A YYGY+W++V++ DM++T+F E LNS VG+ YR IL GG + L
Sbjct: 601 -LAGGYDAQYYGYLWSEVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLR 659
Query: 695 EFLGRKPNNKAFLKELGL 712
FLGR P AFL GL
Sbjct: 660 RFLGRDPKQDAFLLSKGL 677
>Hs14149738 [O] KOG2089 Metalloendopeptidase family - saccharolysin & thimet
oligopeptidase
Length = 704
Score = 396 bits (1018), Expect = e-110
Identities = 231/614 (37%), Positives = 335/614 (53%), Gaps = 23/614 (3%)
Query: 104 LTFLQHVSSDKELRDTSTKVTELIENFGIESSLRFKLFRQFDIVWNQLKDDAQFKKDHFE 163
L F QHVSSDKE+R ST+ + + F IE S+R +F + L++ K E
Sbjct: 106 LDFPQHVSSDKEVRAASTEADKRLSRFDIEMSMRGDIFERIV----HLQETCDLGKIKPE 161
Query: 164 IYKFVEKCHKDFLRSGLNLPEEQRDKVKEIKKKISNNSLQFSKNLGEQNEFITFTKEELI 223
+++EK K R+GL+LPE+ ++++K +KK++S + F+KNL E + F+ F+K EL
Sbjct: 162 ARRYLEKSIKMGKRNGLHLPEQVQNEIKSMKKRMSELCIDFNKNLNEDDTFLVFSKAELG 221
Query: 224 GVSENVMKQFETVDEDGITKYKVTFKYPDIFPVLKSAKNAETRKRAFIGDQNKVPQNEAL 283
+ ++ + E D+D KYK+T KYP FPV+K ETR+R + + + +
Sbjct: 222 ALPDDFIDSLEKTDDD---KYKITLKYPHYFPVMKKCCIPETRRRMEMAFNTRCKEENTI 278
Query: 284 FLETL-QLRNDLAELLNYDSYADYNLDIKMAKKEEAVLTFLNDLKNKLKPXXXXXXXXXX 342
L+ L LR +A+LL Y ++AD+ L++ AK V FL+DL KLKP
Sbjct: 279 ILQQLLPLRTKVAKLLGYSTHADFVLEMNTAKSTSRVTAFLDDLSQKLKPLGEAEREFIL 338
Query: 343 XXXXXXXXXXNTPYDRRYYIWDNRYYDNQYLKKNFQIDEEKIAEYFPLESTIKGMLQIYE 402
YD + WD YY Q + + ID+E + EYFP+E +G+L Y+
Sbjct: 339 NLKKKECKDRGFEYDGKINAWDLYYYMTQTEELKYSIDQEFLKEYFPIEVVTEGLLNTYQ 398
Query: 403 TVLKLKFIEEDNGDTWHPDVKKLSVWKMDDNFPSFVGWIYFDLHPREGKYGHAANFGISS 462
+L L F + + W+ V +V D +G Y DL+PREGKY HAA FG+
Sbjct: 399 ELLGLSFEQMTDAHVWNKSVTLYTV--KDKATGEVLGQFYLDLYPREGKYNHAACFGLQP 456
Query: 463 SFLKSDGSRSYPVTALVCNFSKPTKDKPALLKHSELTTFFHELGHGIHDLVGGNDIGRFN 522
L DGSR V ALV NFS+P +P+LL+H E+ T+FHE GH +H + D RF+
Sbjct: 457 GCLLPDGSRMMAVAALVVNFSQPVAGRPSLLRHDEVRTYFHEFGHVMHQICAQTDFARFS 516
Query: 523 GPSATPWDFVEAPSQMLEFWTWNKKELKSLSKHYQTEEKIPDSLLDSLVRTKHINGALFA 582
G + DFVE PSQMLE W W+ L+ LSKHY+ I D LL+ LV ++ +N L
Sbjct: 517 GTNVET-DFVEVPSQMLENWVWDVDSLRRLSKHYKDGSPIADDLLEKLVASRLVNTGLLT 575
Query: 583 LRQLHFGLFDMKVHTTKDISKLNVTELWNSLREEICLIDNGDIQTKGFN---SFGHIMSD 639
LRQ+ D +HT + L+ + EI G T G N +FGH ++
Sbjct: 576 LRQIVLSKVDQSLHTN---TSLDAASEYAKYCSEIL----GVAATPGTNMPATFGH-LAG 627
Query: 640 SYSAGYYGYMWADVFASDMYYTKF-LEDPLNSDVGVQYRDIILARGGLYEIEDNLTEFLG 698
Y YYGY+W++VF+ DM+Y+ F E +N +VG++YR++IL GG + D L FL
Sbjct: 628 GYDGQYYGYLWSEVFSMDMFYSCFKKEGIMNPEVGMKYRNLILKPGGSLDGMDMLHNFLK 687
Query: 699 RKPNNKAFLKELGL 712
R+PN KAFL GL
Sbjct: 688 REPNQKAFLMSRGL 701
>At5g51540 [O] KOG2090 Metalloendopeptidase family - mitochondrial
intermediate peptidase
Length = 860
Score = 222 bits (566), Expect = 1e-57
Identities = 151/556 (27%), Positives = 253/556 (45%), Gaps = 54/556 (9%)
Query: 174 DFLRSGLNLPEEQRDKVKEIKKKISNNSLQFSKNLGEQ----------------NEFITF 217
DF R G++L E+ DKV + I +FS+N+ + + +
Sbjct: 154 DFERGGIHLDPEKLDKVNNLTTNIFQLCREFSENIADDPGHVDIFPGSRIPRHLHHLLNP 213
Query: 218 TKEELIGVSENVMKQFETVDEDGITKYKVTFKYPDIFPVLKSAKNAETRKRAFIGDQNKV 277
T G S + + G +++ + +L+ + E RK +I +
Sbjct: 214 TYRSTSGGSRGSTRSAHKSKQKG---FRINTDPRTVSSILQWTSDEEVRKMVYIQGNSVP 270
Query: 278 PQNEALFLETLQLRNDLAELLNYDSYADYNLDIKMAKKEEAVLTFLNDLKNKLKPXXXXX 337
N + + + R++L++++ +SYAD ++ +AK + V +FL +L +KP
Sbjct: 271 HANHGVLEKLIAARHELSQMMGCNSYADIMVEPNLAKSPKVVTSFLQELSKTVKPKADEE 330
Query: 338 XXXXXXXXXXXXXXXNTPYDRRYYIWDNRYYDNQYLKKNFQIDEEKIAEYFPLESTIKGM 397
+ + WD YY + +D +A YFPL I+G+
Sbjct: 331 FIAIRDFKREKCGNPSAELEP----WDETYYTSMMKSSINDVDTAVVASYFPLPQCIEGL 386
Query: 398 LQIYETVLKLKF--IEEDNGDTWHPDVKKLSVWKMDDNFPSFVGWIYFDLHPREGKYGHA 455
+ E++ F I G++WHP+V KLS+ D+ +G++Y DL+ R+GKY
Sbjct: 387 KVLVESLFGATFHTIPLAPGESWHPNVVKLSLHHPDEGD---LGYLYLDLYSRKGKYPGC 443
Query: 456 ANFGISSSFLKSDGSRSYPVTALVCNFSKPTKDKPALLKHSELTTFFHELGHGIHDLVGG 515
A+F I S+ PV ALVCNFS+ L HSE+ FHE GH +H L+
Sbjct: 444 ASFAIRGGRKISETEYQLPVIALVCNFSRACDSSIVKLNHSEVEVLFHEFGHALHSLLSR 503
Query: 516 NDIGRFNGPSATPWDFVEAPSQMLEFWTWNKKELKSLSKHYQTEEKIPDSLLDSLVRTKH 575
D F+G + D E PS + E++ W+ + LK ++HY T E IP+ L++SL ++
Sbjct: 504 TDYQHFSG-TRVALDLAEMPSNLFEYYAWDYRLLKRFARHYSTGETIPEKLVNSLQGARN 562
Query: 576 INGALFALRQLHFGLFDMKV-----HTTKDISKLNVTEL------WNSLREEICLIDNGD 624
+ A RQ+ + L D + T +D+S L V EL WN +
Sbjct: 563 MFAATEMQRQVFYALIDQMLFGEQPETARDVSHL-VAELKRQHTSWNHVE---------- 611
Query: 625 IQTKGFNSFGHIMSDSYSAGYYGYMWADVFASDMYYTKFLEDPLNSDVGVQYRDIILARG 684
T + F H++ +Y AGYY Y++A FAS ++ + EDPL+ + G R+ G
Sbjct: 612 -GTHWYIRFSHLL--NYGAGYYSYLYAKCFASTIWQSICEEDPLSLNTGTLLREKFFKHG 668
Query: 685 GLYEIEDNLTEFLGRK 700
G + + LT+ G++
Sbjct: 669 GAKDPAELLTDLAGKE 684
>At1g67700 [O] KOG2089 Metalloendopeptidase family - saccharolysin & thimet
oligopeptidase
Length = 998
Score = 214 bits (545), Expect = 4e-55
Identities = 166/627 (26%), Positives = 290/627 (45%), Gaps = 36/627 (5%)
Query: 82 SVENFVTPYLHHENTISPLFNQLTFLQHVSSDKELRDTSTKVTELIENFGIESSLRFKLF 141
S EN V P E L F + +S +R ST+ + I+ + R ++
Sbjct: 73 SYENVVLPLAELEARQLSLIQCCVFPKMLSPHDNVRKASTEAEQKIDAHILSCRKREDVY 132
Query: 142 RQFDIVWNQLKDDAQFKKDHFEIYKFVEKCHKDFLRSGLNLPEEQRDKVKEIKKKISNNS 201
R I A+ + E +++ +DF +GLNL +R++V+ +K +I S
Sbjct: 133 RIIKIY------AAKGESISPEAKCYLQCLVRDFEDNGLNLTAIKREEVERLKYEIDELS 186
Query: 202 LQFSKNLGEQNEFITFTKEELIGVSENVMKQFETVDEDGITKYKVTFKYPDIFPVLKSAK 261
L++ +NL E + + FT++EL G+ ++ E ++K+T + + +L+ K
Sbjct: 187 LRYIQNLNEDSSCLFFTEDELAGLPLEFLQNLEKTQNK---EFKLTLESRHVAAILELCK 243
Query: 262 NAETRKRAFIGDQNKVPQNEALFLETL-QLRNDLAELLNYDSYADYNLDIKMAKKEEAVL 320
A+TRK + + L+ L Q R+ LA + Y +ADY LD +M+K V+
Sbjct: 244 IAKTRKTVAMAYGKRCGDTNIPVLQRLVQSRHRLACVCGYAHFADYALDRRMSKTSMRVI 303
Query: 321 TFLNDLKNKLKPXXXXXXXXXXXXXXXXXXXXNTPYDRRYYIWDNRYYDNQYLKKNFQID 380
FL D+ + L P+ + D YY + + F +D
Sbjct: 304 RFLEDISSSL--TDLAIREFSILEDLKRKEEGEIPFG----VEDLLYYIKRVEELQFDLD 357
Query: 381 EEKIAEYFPLESTIKGMLQIYETVLKLKFIEEDNGDTWHPDVKKLSVWKMDDNFPSFVGW 440
I +YFP+ + G+ +I + + +KF E D W+ D++ +V+ D +G+
Sbjct: 358 FGDIRQYFPVNLVLSGIFKICQDLFGIKFEEVTEVDVWYHDIRAFAVF--DSGSGKLLGY 415
Query: 441 IYFDLHPREGKYGHAANFGISSSFLKSDGSRSYPVTALVCNFSKPTKDKPALLKHSELTT 500
Y D+ REGK H+ + ++ L S+G+ PV L+ F+K + L S++
Sbjct: 416 FYLDMFTREGKCNHSCVVALQNNALFSNGACQIPVALLIAQFAKDGSGEAVPLGFSDVVN 475
Query: 501 FFHELGHGIHDLVGGNDIGRFNGPSATPWDFVEAPSQMLEFWTWNKKELKSLSKHYQTEE 560
FHE GH + + RF+G P DF E PSQ+LE W +
Sbjct: 476 LFHEFGHVVQHICNRASFARFSGLRVDP-DFREIPSQLLENW-------------QDITK 521
Query: 561 KIPDSLLDSLVRTKHINGALFALRQLHFGLFDMKVHTTKDISKLNVTELWNSLREEICLI 620
+ D + +L R ++ AL +L+++ + LFD +++ D L +L SL ++ +
Sbjct: 522 PLVDEVCKTLKRWRYSFSALKSLQEILYCLFDQIIYSDDDADLL---QLIRSLHPKVMIG 578
Query: 621 DNGDIQTKGFNSFGHIMSDSYSAGYYGYMWADVFASDMYYTKFLEDPLNSDVGVQYRDII 680
T + F + S A Y +W++V+A+D++ +KF + N G+Q+RD +
Sbjct: 579 LPVVEGTNPASCFPRAVIGS-EATCYSRLWSEVYAADIFASKFGDGHPNLYAGLQFRDKV 637
Query: 681 LARGGLYEIEDNLTEFLGRKPNNKAFL 707
LA GG E + LT FLGR+P+ +AF+
Sbjct: 638 LAPGGGKEPMELLTNFLGREPSTQAFI 664
>At5g65620 [O] KOG2089 Metalloendopeptidase family - saccharolysin & thimet
oligopeptidase
Length = 714
Score = 207 bits (528), Expect = 3e-53
Identities = 168/675 (24%), Positives = 305/675 (44%), Gaps = 74/675 (10%)
Query: 81 PSVENFVTPYLHHENTISPLFNQLTFLQHVSSDKELRDTSTKVTELIENFGIESSLRFKL 140
P+ V P + ++ ++ + L+ V ELR V F + +
Sbjct: 64 PTWPKLVEPLEKIVDRLTVVWGMINHLKAVKDTPELRAAIEDVQPEKVKFQLRLGQSKPI 123
Query: 141 FRQFDIV-----WNQLKDDAQFKKDHFEIYKFVEKCHKDFLRSGLNLPEEQRDKVKEIKK 195
+ F + W+ L + Q + VE K+ + G+ L +E+R++ +I++
Sbjct: 124 YNAFKAIRESPDWSSLSEARQ---------RLVEAQIKEAVLIGIALDDEKREEFNKIEQ 174
Query: 196 KISNNSLQFSKNLGEQN---EFITFTKEELIGVSENVMKQF----------ETVDEDGIT 242
++ S +FS+N+ + E + K+E+ G+ + + F E+G
Sbjct: 175 ELEKLSHKFSENVLDATKKFEKLITDKKEIEGLPPSALGLFAQAAVSKGHENATAENG-- 232
Query: 243 KYKVTFKYPDIFPVLKSAKNAETRKRAFIGDQNKVPQ----NEALFLETLQLRNDLAELL 298
+ +T P PV++ AKN R+ + ++ N A+ + L+LR + A+LL
Sbjct: 233 PWIITLDAPSYLPVMQHAKNRALREEVYRAYLSRASSGDLDNTAIIDQILKLRLEKAKLL 292
Query: 299 NYDSYADYNLDIKMAKKEEAVLTFLNDLKNKLKPXXXXXXXXXXXXXXXXXXXXNTPYDR 358
Y++YA+ ++ +KMA E+A +L KL+
Sbjct: 293 GYNNYAEVSMAMKMATVEKAA-----ELLEKLRSASWDAAVQDMEDLKSFAKNQGAAESD 347
Query: 359 RYYIWDNRYYDNQYLKKNFQIDEEKIAEYFPLESTIKGMLQIYETVLKLKFIEEDN-GDT 417
WD ++ + + + I+EE++ YF L + G+ + +T+ + D
Sbjct: 348 SMTHWDTTFWSERLRESKYDINEEELRPYFSLPKVMDGLFSLAKTLFGIDIEPADGLAPV 407
Query: 418 WHPDVKKLSVWKMDDNFPSFVGWIYFDLH--PREGKYGHAANFGISSSFLKSDGSRSY-- 473
W+ DV+ +++ D+ + + + YFD + P E + G + +S S + + S
Sbjct: 408 WNNDVR---FYRVKDSSGNPIAYFYFDPYSRPSEKRGGAWMDEVVSRSRVMAQKGSSVRL 464
Query: 474 PVTALVCNFSKPTKDKPALLKHSELTTFFHELGHGIHDLVGGNDIGRFNGPSATPWDFVE 533
PV +VCN + P DKP+L+ E+ T FHE GH + ++ D G G WD VE
Sbjct: 465 PVAHMVCNQTPPVGDKPSLMTFREVETVFHEFGHALQHMLTKQDEGLVAGIRNIEWDAVE 524
Query: 534 APSQMLEFWTWNKKELKSLSKHYQTEEKIPDSLLDSLVRTKHINGALFALRQLHFGLFDM 593
PSQ +E W +++ L S++KHY+T E +P+ + L+ + F+LRQL F D+
Sbjct: 525 LPSQFMENWCYHRDTLMSIAKHYETGETLPEEVYKKLLAARTFRAGSFSLRQLKFASVDL 584
Query: 594 KVHT---------TKDI-SKLNV-TELWNSLREEICLIDNGDIQTKGFNSFGHIMSDSYS 642
++HT D+ +++V T++ L E+ L SF HI + Y+
Sbjct: 585 ELHTKYVPGGPESIYDVDQRVSVKTQVIPPLPEDRFLC-----------SFSHIFAGGYA 633
Query: 643 AGYYGYMWADVFASDMYYTKFLEDPLN-----SDVGVQYRDIILARGGLYEIEDNLTEFL 697
AGYY Y WA+V ++D ++ F + L+ + G ++R+ ILA GG EF
Sbjct: 634 AGYYSYKWAEVLSADA-FSAFEDAGLDDIKAVKETGQRFRNTILALGGGKAPLKVFVEFR 692
Query: 698 GRKPNNKAFLKELGL 712
GR+P+ + L+ GL
Sbjct: 693 GREPSPEPLLRHNGL 707
>At5g10540 [O] KOG2089 Metalloendopeptidase family - saccharolysin & thimet
oligopeptidase
Length = 723
Score = 200 bits (508), Expect = 7e-51
Identities = 153/578 (26%), Positives = 268/578 (45%), Gaps = 48/578 (8%)
Query: 173 KDFLRSGLNLPEEQRDKVKEIKKKISNNSLQFSKNLGEQN---EFITFTKEELIGVSEN- 228
K+ + SG+ L +++R++ +I++++ S +FS+N+ + E + K+E+ G+ +
Sbjct: 151 KEAVLSGIALEDDKREEFNKIEQELEKLSHKFSENVLDATKKFEKLITDKKEIEGLPPSA 210
Query: 229 --------VMKQFETVDEDGITKYKVTFKYPDIFPVLKSAKNAETRKRAFIGDQNKVPQ- 279
V K ET D + +T P PV++ AKN R+ + ++
Sbjct: 211 LGLFAQAAVSKGHETATAD-TGPWLITLDAPSYLPVMQHAKNRALREEVYRAYLSRASSG 269
Query: 280 ---NEALFLETLQLRNDLAELLNYDSYADYNLDIKMAKKEEAVLTFLNDLKNKLKPXXXX 336
N A+ + L+LR + A+LL Y +YA+ ++ KMA E+A ++L KL+
Sbjct: 270 DLDNTAIIDQILKLRLEKAKLLGYRNYAEVSMATKMATVEKA-----DELLEKLRSASWD 324
Query: 337 XXXXXXXXXXXXXXXXNTPYDRRYYIWDNRYYDNQYLKKNFQIDEEKIAEYFPLESTIKG 396
WD ++ + + + I+EE++ YF L +
Sbjct: 325 PAVQDIEDLKSFAKNQGAAEADSLTHWDITFWSERLRESKYDINEEELRPYFSLPKVMDA 384
Query: 397 MLQIYETVLKLKFIEEDN-GDTWHPDVKKLSVWKMDDNFPSFVGWIYFDLHPREGKYGHA 455
+ + +T+ + + D W+ DV+ V D+ + + YFD + R +
Sbjct: 385 LFGLAKTLFGIDVVPADGVAPVWNSDVRFYCV---KDSSGNPTAYFYFDPYSRPSEKRDG 441
Query: 456 A----NFGISSSFLKSDGSRSYPVTALVCNFSKPTKDKPALLKHSELTTFFHELGHGIHD 511
A F S + S PV +VCN + P DKP+L+ E+ T FHE GH +
Sbjct: 442 AWMDEVFSRSRVMAQKGSSVRLPVAQMVCNQTPPVGDKPSLMTFREVETVFHEFGHALQH 501
Query: 512 LVGGNDIGRFNGPSATPWDFVEAPSQMLEFWTWNKKELKSLSKHYQTEEKIPDSLLDSLV 571
++ D G G WD VE PSQ +E W +++ L S++KHYQT E +P+++ L+
Sbjct: 502 MLTKEDEGLVAGIRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYQTGETLPENVYKKLL 561
Query: 572 RTKHINGALFALRQLHFGLFDMKVHT------TKDISKLN-----VTELWNSLREEICLI 620
+ +LRQL F D+++HT + I +++ T++ L E+ L
Sbjct: 562 AARTFRAGSLSLRQLKFATVDLELHTKYMPGGAETIYEVDQRVSIKTQVIPPLPEDRFLC 621
Query: 621 DNGDIQTKGFN-SFGHIMSDSYSAGYYGYMWADVFASDMYYTKFLEDPLN-----SDVGV 674
I F S H++S Y+AGYY Y WA+V ++D ++ F + L+ + G
Sbjct: 622 SFSHIFAVCFTCSPSHVLSGGYAAGYYSYKWAEVLSADA-FSAFEDAGLDDIKAVKETGQ 680
Query: 675 QYRDIILARGGLYEIEDNLTEFLGRKPNNKAFLKELGL 712
++R+ ILA GG EF GR+P+ + L+ GL
Sbjct: 681 RFRNTILALGGGKAPLKVFVEFRGREPSPEPLLRHNGL 718
>7302217 [O] KOG2090 Metalloendopeptidase family - mitochondrial
intermediate peptidase
Length = 699
Score = 179 bits (454), Expect = 1e-44
Identities = 135/532 (25%), Positives = 232/532 (43%), Gaps = 36/532 (6%)
Query: 174 DFLRSGLNLPEEQRDKVKEIKKKISNNSLQFSKNLGEQNEFITFTKEELIGVSENVMKQF 233
DF + G++LPEE+R +V + I +F + + + + V E+ F
Sbjct: 170 DFEQCGIHLPEEERMRVVRLNDYILQLGQKFMSGAVQPS---VLPRSQ---VPESFRNYF 223
Query: 234 ETVDEDGITKYKVTFKYPDIFPVLKSAKNAETRKRAFIGDQNKVPQNEALFLETLQLRND 293
T E+ I I + +A+N + R+ A+ E L + L R++
Sbjct: 224 PTSGENVI-----------ITGLCTNAENVQMREAAYRLYLQPSKSQEDLLRDLLLCRHE 272
Query: 294 LAELLNYDSYADYNLDIKMAKKEEAVLTFLNDLKNKLKPXXXXXXXXXXXXXXXXXXXXN 353
LA +D+YA L +K E V F+++L KL+P
Sbjct: 273 LARSCGFDTYAHRALKGSTMEKPEVVREFIDELSEKLRPRADCDFALMSQMKRREGGKA- 331
Query: 354 TPYDRRYYIWDNRYYDNQYLKKNFQIDEEKIAEYFPLESTIKGMLQIYETVLKLKFIEED 413
D R +WD YY NQ ++ F+ + YF L ++G+ + + ++ D
Sbjct: 332 ---DARAEVWDTPYYTNQLRRQLFEEHANEFLPYFSLGGCMEGLDNLLHALYGIRLQNTD 388
Query: 414 --NGDTWHPDVKKLSVWKMDDNFPSFVGWIYFDLHPREGKYGHAANFGISSSFLKSDGSR 471
G+ WH D+ KL+V + +G+IY D + R GK +F I DGS
Sbjct: 389 LKPGEAWHNDIYKLAVVHEREGL---LGYIYCDFYERVGKPNQDCHFTIQGGKRMPDGSY 445
Query: 472 SYPVTALVCNFSKPTKDKPALLKHSELTTFFHELGHGIHDLVGGNDIGRFNGPSATPWDF 531
PV ++ ++P P LL + L FHE+GH +H ++ + G + DF
Sbjct: 446 QLPVVVVMLGLAQPRWSGPTLLSPARLDNLFHEMGHAMHSMLARTEHQHVTGTRCST-DF 504
Query: 532 VEAPSQMLEFWTWNKKELKSLSKHYQTEEKIPDSLLDSLVRTKHINGALFALRQLHFGLF 591
E PS ++E++ + + L++ ++H+QT E I + +L L +K++ A Q+ +
Sbjct: 505 AEVPSVLMEYFAGDPRVLRTFARHFQTHEPISEDMLRRLCASKNLFAASETQLQVFYSAL 564
Query: 592 DMKVHTTKDISKLNVTELWNSLREE---ICLIDNGDIQTKGFNSFGHIMSDSYSAGYYGY 648
D + H + T+ S+++ + +DN Q + F H++ Y A YY Y
Sbjct: 565 DQEYHGASARHGQSSTDTLRSVQDHYYGLPYVDNTAWQLR----FSHLV--GYGAKYYAY 618
Query: 649 MWADVFASDMYYTKFLEDPLNSDVGVQYRDIILARGGLYEIEDNLTEFLGRK 700
+ + AS ++ T F +P N G +YR ILA GG + FL R+
Sbjct: 619 LVSKTIASWIWQTYFEANPFNRQAGEKYRAEILAHGGAVPSRKLVANFLQRE 670
>SPAC1F3.10c [O] KOG2090 Metalloendopeptidase family - mitochondrial
intermediate peptidase
Length = 762
Score = 167 bits (423), Expect = 5e-41
Identities = 140/553 (25%), Positives = 242/553 (43%), Gaps = 61/553 (11%)
Query: 173 KDFLRSGLNLPEEQRDK-VKEIKKKISNNSLQFSKNLGEQNEFITFTKEELIGVSENVMK 231
+DF +SG+NL +R+ VK+ + + F+ ++ ++T +K+ L G ++
Sbjct: 192 QDFEKSGVNLESSKRNSFVKKSSESATLGRAFFNNSMNRPQRYLTISKQRLAGSDPYFVR 251
Query: 232 QFETVDEDGITKYKVTFKYPDIFPVLKSAKNAETRKRAFIGDQNKVPQNEALFLETLQLR 291
D++ I V ++ L S N + RK ++ + L L+ +
Sbjct: 252 SLSKNDKNFIMIPTVGYEGTQ---ALISVANPDVRKEIYMEGHKGTVEEVELLNSYLRSK 308
Query: 292 NDLAELLNYDSYADYNLDIKMAKKEEAVLTFLNDLKNKLKPXXXXXXXXXXXXXXXXXXX 351
++A+L+ S+AD L KMA + V+ FL +L K
Sbjct: 309 AEVAKLVGKSSFADLQLIDKMANAPKHVVEFLENLSLK---NSSVLKKILNNLALMKKKE 365
Query: 352 XNTPYDRRYYIWDNRYYDNQYL------KKNFQIDEEKIAEYFPLESTIKGMLQIYETVL 405
N + + +WD YY +Y K + +F + + I+G+ +++ ++
Sbjct: 366 LNLNFLPSFDVWDREYYTARYKQSLINQKPSLNPSITNYRRFFSVGTVIQGLSRLFSSLY 425
Query: 406 KLKFIEED--NGDTWHPDVKKLSVWKMDDNFPSFVGWIYFDLHPREGKYGHAANFGISSS 463
L+F+ D G+ WHPDV K++V+ +D+ +G IYFDL R GK AA+F I SS
Sbjct: 426 GLRFVPADISPGEVWHPDVNKVNVYNENDHV---MGVIYFDLFARTGKTDGAAHFTIRSS 482
Query: 464 F----------------------LKSDGSRSYPVTALVCNFSKPTKDKPALLKHSELTTF 501
+K + PV +L+CNF + + P L ++ T
Sbjct: 483 RELDLTSFDDSISLGFDDATNIRVKDNKRYQIPVISLLCNFVRSSGMDPTFLDLWDVKTL 542
Query: 502 FHELGHGIHDLVGGNDIGRFNGPSATPWDFVEAPSQMLEFWTWNKKELKSLSKHYQTEEK 561
FHE+GH +H ++G G DFVE PS ++EF+ N L +++ TE
Sbjct: 543 FHEMGHAMHSILGHTKYQNLAGTRCAT-DFVELPSIIMEFFMSNPAVLPLYARYEGTEIP 601
Query: 562 IPDSLLDSLVRTKHINGALFALRQLHFGLFDMKVHTTKDISKLNVTELWNSLREEICLID 621
+P +L+ ++ + L Q+ + D H SK+ + +NS+ E +
Sbjct: 602 LPVQVLNHHNMVENSSAPLDLQSQICMAMVDQLFH-----SKVVLDPSFNSIDE----VT 652
Query: 622 NGDIQTKGFNS---------FGHIMSDSYSAGYYGYMWADVFASDMYYTKFLEDPLNSDV 672
N + GF S F H+ YSA YY Y++ V AS ++ F +PL+ +
Sbjct: 653 NVTRKFSGFESAPPAAWYLQFSHLY--GYSATYYSYIFDTVLASLIFSKLFAGNPLSREA 710
Query: 673 GVQYRDIILARGG 685
G ++R IL GG
Sbjct: 711 GEKFRKAILRWGG 723
>YKL134c [O] KOG2090 Metalloendopeptidase family - mitochondrial
intermediate peptidase
Length = 770
Score = 157 bits (396), Expect = 7e-38
Identities = 142/547 (25%), Positives = 244/547 (43%), Gaps = 47/547 (8%)
Query: 174 DFLRSGLNLPEEQRDKVKEIKKKISNNSLQFSKNL---GEQNEFITFTKEELIGVSENVM 230
DF +SG+ + + R+K ++ ++IS +F + G + I + VS ++
Sbjct: 204 DFEKSGIYMNPDVREKFIQLSQEISLVGQEFINHTDYPGSNSVKIPCKDLDNSKVSTFLL 263
Query: 231 KQFETVDEDGITKYKV-TFKYPDIFPVLKSAKNAETRKRAFIGDQNKVPQNEALFLETLQ 289
KQ D G YKV TF Y + +LKS +N RK+ + + + ++
Sbjct: 264 KQLNK-DVKG-QNYKVPTFGYA-AYALLKSCENEMVRKKLWTALHSCSDKQVKRLSHLIK 320
Query: 290 LRNDLAELLNYDSYADYNLDIKMAKK--EEAVLTFLNDLKNKLKPXXXXXXXXXXXXXXX 347
LR LA L++ SYA+Y L+ K + ++ +LT +N+ K
Sbjct: 321 LRAILANLMHKTSYAEYQLEGKWQDRRCQDFILTLMNNTIEKTANELKFIAELKAKDLKK 380
Query: 348 XXXXXNTPYDRRYYIWDNRYYDNQYLKKN--FQIDEEKIAEYFPLESTIKGMLQIYETV- 404
+ WD YY +Y + N + ++I+ YF L + I+G+ +++ +
Sbjct: 381 PLTTNTDEILKLVRPWDRDYYTGKYFQLNPSNSPNAKEISYYFTLGNVIQGLSDLFQQIY 440
Query: 405 -LKLKFIEEDNGDTWHPDVKKLSVWKMDDNFPSFVGWIYFDLHPREGKYGHAANFGISSS 463
++L+ D G+TW PDV++L+V ++ +G IY DL R GK + A+F + S
Sbjct: 441 GIRLEPAITDEGETWSPDVRRLNVISEEEGI---IGIIYCDLFERNGKTSNPAHFTVCCS 497
Query: 464 FL---------------KSDGSR-SYPVTALVCNFSK---PTKDKPALLKHSELTTFFHE 504
DG+ PV +LVCNFS +K L+ SE+ T FHE
Sbjct: 498 RQIYPSETDFSTIQVGENPDGTYFQLPVISLVCNFSPILIASKKSLCFLQLSEVETLFHE 557
Query: 505 LGHGIHDLVGGNDIGRFNGPSATPWDFVEAPSQMLEFWTWNKKELKSLSKHYQTEEKIPD 564
+GH +H ++G + +G DFVE PS ++E + + + L + KHY T E I
Sbjct: 558 MGHAMHSMLGRTHMQNISGTRCAT-DFVELPSILMEHFAKDIRILTKIGKHYGTGETIQA 616
Query: 565 SLLDSLVRTKHINGALFALRQLHFGLFDMKVHTTK---DISKLNVTELWNSLREEICLID 621
+L +++ + Q + D H K DI +V E + +L + ++
Sbjct: 617 DMLQRFMKSTNFLQNCETYSQAKMAMLDQSFHDEKIISDIDNFDVVENYQALERRLKVL- 675
Query: 622 NGDIQTKGFNSFGHIMSDS--YSAGYYGYMWADVFASDMYYTKFLEDPLNSDVGVQYRDI 679
D Q+ FGH+ +A Y+ AS ++Y F +DP + G +++
Sbjct: 676 -VDDQSNWCGRFGHLFGSGQLITATYFD----RTIASKIWYALFEDDPYSRKNGDKFKKH 730
Query: 680 ILARGGL 686
+L GGL
Sbjct: 731 LLKWGGL 737
>Hs20548472 [O] KOG2090 Metalloendopeptidase family - mitochondrial
intermediate peptidase
Length = 713
Score = 153 bits (386), Expect = 1e-36
Identities = 106/405 (26%), Positives = 183/405 (45%), Gaps = 21/405 (5%)
Query: 286 ETLQLRNDLAELLNYDSYADYNLDIKMAKKEEAVLTFLNDLKNKLKPXXXXXXXXXXXXX 345
E L R+ LA+L+ Y +++ L +AK E V+ FL L +KL
Sbjct: 284 ELLSSRDLLAKLVGYSTFSHRALQGTIAKNPETVMQFLEKLSDKLSERTLKDFEMIRGMK 343
Query: 346 XXXXXXXNTPYDRRYYIWDNRYYDNQYLKKNFQIDEEKIAEYFPLESTIKGMLQIYETVL 405
P + WD YY + + I+ +F L + ++G+ + +L
Sbjct: 344 MKL-----NPQNSVIMPWDPPYYSGVIRAERYNIEPSLYCPFFSLGACMEGLNILLNRLL 398
Query: 406 KLKFIEED--NGDTWHPDVKKLSVWKMDDNFPSFVGWIYFDLHPREGKYGHAANFGISSS 463
+ E G+ W DV+KL+V + +G+IY D R K +F I
Sbjct: 399 GISLYAEQPAKGEVWSEDVRKLAVVHESEGL---LGYIYCDFFQRADKPHQDCHFTIRGG 455
Query: 464 FLKSDGSRSYPVTALVCNFSKPTKDKPALLKHSELTTFFHELGHGIHDLVGGNDIGRFNG 523
LK DG PV L+ N + ++ P LL S + FHE+GH +H ++G G
Sbjct: 456 RLKEDGDYQLPVVVLMLNLPRSSRSSPTLLTPSMMENLFHEMGHAMHSMLGRTRYQHVTG 515
Query: 524 PSATPWDFVEAPSQMLEFWTWNKKELKSLSKHYQTEEKIPDSLLDSLVRTKHINGALFAL 583
+ P DF E PS ++E++ + + + ++HYQT + +P +++ L +K + A
Sbjct: 516 -TRCPTDFAEVPSILMEYFANDYRVVNQFARHYQTGQPLPKNMVSRLCESKKVCAAADMQ 574
Query: 584 RQLHFGLFDMKVHTTKDISKLNVTELWNSLREE---ICLIDNGDIQTKGFNSFGHIMSDS 640
Q+ + D +++ K + + T++ +E+ + + N Q + F H++
Sbjct: 575 LQVFYATLD-QIYHGKHPLRNSTTDILKETQEKFYGLPYVPNTAWQLR----FSHLV--G 627
Query: 641 YSAGYYGYMWADVFASDMYYTKFLEDPLNSDVGVQYRDIILARGG 685
Y A YY Y+ + AS ++ FL+DP N G +YR +LA GG
Sbjct: 628 YGARYYSYLMSRAVASMVWKECFLQDPFNRAAGERYRREMLAHGG 672
>Hs5174567 [O] KOG2090 Metalloendopeptidase family - mitochondrial
intermediate peptidase
Length = 713
Score = 148 bits (374), Expect = 2e-35
Identities = 103/405 (25%), Positives = 181/405 (44%), Gaps = 21/405 (5%)
Query: 286 ETLQLRNDLAELLNYDSYADYNLDIKMAKKEEAVLTFLNDLKNKLKPXXXXXXXXXXXXX 345
E L R+ LA+L+ Y +++ L +AK E V+ FL L +KL
Sbjct: 284 ELLSSRDLLAKLVGYSTFSHRALQGTIAKNPETVMQFLEKLSDKLSERTLKDFEMIRGMK 343
Query: 346 XXXXXXXNTPYDRRYYIWDNRYYDNQYLKKNFQIDEEKIAEYFPLESTIKGMLQIYETVL 405
+ WD YY + + I+ +F L + ++G+ + +L
Sbjct: 344 MKLNAQNSEVMP-----WDPPYYSGVIRAERYNIEPSLYCPFFSLGACMEGLNILLNRLL 398
Query: 406 KLKFIEED--NGDTWHPDVKKLSVWKMDDNFPSFVGWIYFDLHPREGKYGHAANFGISSS 463
+ E G+ W DV+KL+V + +G+IY D R K +F I
Sbjct: 399 GISLYAEQPAKGEVWSEDVRKLAVVHESEGL---LGYIYCDFFQRADKPHQDCHFTIRGG 455
Query: 464 FLKSDGSRSYPVTALVCNFSKPTKDKPALLKHSELTTFFHELGHGIHDLVGGNDIGRFNG 523
LK DG P+ L+ N + ++ P LL + FHE+GH +H ++G G
Sbjct: 456 RLKEDGDYQLPLVVLMLNLPRSSRSSPTLLTPGMMENLFHEMGHAMHSMLGRTRYQHVTG 515
Query: 524 PSATPWDFVEAPSQMLEFWTWNKKELKSLSKHYQTEEKIPDSLLDSLVRTKHINGALFAL 583
+ P DF E PS ++E++ + + + ++HYQT + +P +++ L +K + A
Sbjct: 516 -TRCPTDFAEVPSILMEYFANDYRVVNQFARHYQTGQPLPKNMVSRLCESKKVCAAADMQ 574
Query: 584 RQLHFGLFDMKVHTTKDISKLNVTELWNSLREE---ICLIDNGDIQTKGFNSFGHIMSDS 640
Q+ + D +++ K + + T++ +E+ + + N Q + F H++
Sbjct: 575 LQVFYATLD-QIYHGKHPLRNSTTDILKETQEKFYGLPYVPNTAWQLR----FSHLV--G 627
Query: 641 YSAGYYGYMWADVFASDMYYTKFLEDPLNSDVGVQYRDIILARGG 685
Y A YY Y+ + AS ++ FL+DP N G +YR +LA GG
Sbjct: 628 YGARYYSYLMSRAVASMVWKECFLQDPFNRAAGERYRREMLAHGG 672
>7301239 [O] KOG2089 Metalloendopeptidase family - saccharolysin & thimet
oligopeptidase
Length = 730
Score = 121 bits (304), Expect = 3e-27
Identities = 108/447 (24%), Positives = 185/447 (41%), Gaps = 23/447 (5%)
Query: 274 QNKVPQNEALFLETLQLRNDLAELLNYDSYADYNLDIKMAKKEEAVLTFLNDLKNKLKPX 333
Q K +N + LR A LL Y+S+AD ++ KM + L + KL
Sbjct: 289 QEKSLENSTHIEKIRGLRKRQANLLGYESFADMSMQTKMVGSVDN----LKQIFAKLLKF 344
Query: 334 XXXXXXXXXXXXXXXXXXXNTPYDRRYYIWDNRYYDNQYLKKNFQIDEEKIAEYFPLEST 393
Y Y D Y+ + L + ++K+ E+FPL
Sbjct: 345 AGPAQSVELEKLQGFAQDSGCEYKLEAY--DVAYWRRKQLAAEHGLQDQKLREFFPLPRV 402
Query: 394 IKGMLQIYETVLKLKFIEEDNGDTWHPDVKKLSVWKMDD-NFPSFVGWIYFDLHPREGKY 452
+ G+ + E + +K +E+ N + WHP VK V+ D N + VG Y D + +E K+
Sbjct: 403 LSGLFALSEKLFGIKIVEQPNAEVWHPAVKFYDVFDADSVNSSTPVGGFYVDCYSKEHKF 462
Query: 453 GHAANFGISSSFLKSDGSRSY-PVTALVCNFSKPTKD--KPALLKHSELTTFFHELGHGI 509
G N G S+ S P+ AL+ NFS+P KP LL + +L F G G+
Sbjct: 463 GR--NNGWMVGIRNSNKSAGLTPLCALIFNFSEPQSPDAKPPLLGYDDLQMLFKTFGSGL 520
Query: 510 HDLVGGNDIGRFNGPSATPWDFVEAPSQMLEFWTWNKKELKSLSKHYQTEEKIPDSLLDS 569
L+ G S WD + ++ + + ++SLS H+ + E + L
Sbjct: 521 QHLLTQAGYSDLAGLSNIEWDASQVSGHVMSNFLDDPTVIRSLSGHFSSGEPLEAELSQK 580
Query: 570 LVRTKHINGALFALRQLHFGLFDMKVHTTKDISKLNVTELWNSLREEICL-IDNGDIQTK 628
+ K + L+ D+++H + V +LW + C+ +D D
Sbjct: 581 MRLLKTQLAGYNLCQDLYLADLDVELHRSNAFWLEVVRKLWPVYQ---CMPLDKKDAHP- 636
Query: 629 GFNSFGHIMSDSYSAGYYGYMWADVFASDMYYTKFLEDPLNSD---VGVQYRDIILARGG 685
S I + ++A + ++++ + A+D+ + F E + VG +Y+ L+ GG
Sbjct: 637 --CSLTDIFAGDWAAAQFSHLYSRLIAADI-SSSFAEQRSEENYAVVGRRYKQTFLSCGG 693
Query: 686 LYEIEDNLTEFLGRKPNNKAFLKELGL 712
+ F GR P+ +A LK L +
Sbjct: 694 SVPTAEVFRRFQGRDPSAEALLKSLDI 720
>CE28378 [O] KOG2090 Metalloendopeptidase family - mitochondrial
intermediate peptidase
Length = 784
Score = 85.9 bits (211), Expect = 2e-16
Identities = 135/693 (19%), Positives = 268/693 (38%), Gaps = 107/693 (15%)
Query: 107 LQHVSSDKELR----DTSTKVTELIENFGIESSLRFKLFRQFDIVWNQLKDDAQFKKDHF 162
++ + S+ E R D S EL+E+ ++L KL + +I + DD +
Sbjct: 95 VRQLHSEPEFRNAAEDVSRNFCELVESLNTNTALYQKL-KSSEITESSRLDDVDKRT--- 150
Query: 163 EIYKFVEKCHKDFLRSGLNLPEEQRDKVKEIKKKISNNSLQFSKNLGE-------QNEFI 215
+ DF +SG++L + Q+++ ++ +I + +F +N FI
Sbjct: 151 -----LTLLLDDFEQSGVHLKDNQKEQFVQLSSEIFDAGARFQQNCDRIVSVGNFSAIFI 205
Query: 216 TFTKEELIGVSENVM---KQFETVDE-----DGITKY-KVTFKYPD-IFPVLKSAKNAET 265
F+ +++ E + K F+T + + + K+ + + P I+ + ++ +
Sbjct: 206 HFSDNKMLNCHERIYFSKKNFKTPQKWMKIAEKLKKFDQAKYGLPSQIYTPVSNSLDRSK 265
Query: 266 RKRAFIGDQNKVPQNEALFLETLQLRNDLAELLNYDSYADYNLDIKMAKKEEAVLTFLND 325
RK + E+ + R+ L++L ++S+A + + + V +FL
Sbjct: 266 RKMVYNTFYRHDDIQESYLQHLISSRHQLSQLTGFESFAHRAQRNSLLENYDTVRSFLWG 325
Query: 326 LKNKLKPXXXXXXXXXXXXXXXXXXXXNTPYD------------------RRYYIWDNRY 367
+ K + N + R YY R
Sbjct: 326 VVEKCRGAFEKELAVLIDVSAQCSQQDNNNGNNEISTIAEHDLGFLMHLYRVYYTHPTRK 385
Query: 368 YD--------------------NQYLKKNFQIDEEKI-----------------AEYFPL 390
Y N L+ N + KI + +F
Sbjct: 386 YSSMSRRDWNIFVHCAFEGYCSNFELRGNINVKNGKIKRISESAYDIAQVSQQSSPFFTF 445
Query: 391 ESTIKGMLQIYETVLKLKFIEED--NGDTWHPD-VKKLSVWKMDDNFPSFVGWIYFDLHP 447
S G + + + ++ IEE +G+ W+ V KL +N +G IY D+
Sbjct: 446 NSIWNGFSTLTQRLYGVRLIEEPLISGEMWNSSGVMKLQAVDEQNNE---LGVIYVDVSI 502
Query: 448 REGKYGHAANFGISSSFLKSDGSRSYPVTALVCNF--SKPTKDKPALLKHSELTTFFHEL 505
R K ++ + S SDG+ P+ L ++ + + + T FHEL
Sbjct: 503 RPEKAVGDCHYTVRCSKQLSDGTWQMPILVLSLGLVDGHSSQWRNSRVSFHSAETMFHEL 562
Query: 506 GHGIHDLVGGNDIGRFNGPSATPWDFVEAPSQMLEFWTWNKKELKSLSKHY-QTEEKIPD 564
GH +H ++G G + P DF E PS ++E++ + + + + + EE++
Sbjct: 563 GHAMHSILGRTKYQHVAG-TRCPQDFSEIPSNLMEYFFSDLGVMTDIIRRTDRPEEQLSI 621
Query: 565 SLLDSLVRTKHINGALFALRQLHFGLFDMKVH---TTKDIS--KLNVTELWNSLREEICL 619
+L+ ++H A+ ++Q +GL+D++VH I+ ++ TEL++ + +
Sbjct: 622 ESAATLLASRHSFTAIETVQQAAYGLYDLEVHGPIAAPQIASGRMTTTELFHDIMNKTM- 680
Query: 620 IDNGDIQTKGFNSFGHIMSDS--YSAGYYGYMWADVFASDMYYTKFLEDPLNSDVGVQYR 677
IQ ++F H + Y A YY Y+ A A ++ +FL DP + G +
Sbjct: 681 ---PHIQRSPDSAFQHRFHHTVQYGAKYYSYLVARASACLIWQQRFLNDPFSRKWGDCWA 737
Query: 678 DIILARGGLYEIEDNLTEFLGRKPNNKAFLKEL 710
+ + + GG + L + LG +P + L
Sbjct: 738 E-VQSHGGGHHPAVLLEKILGFRPTENDLTQAL 769
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,294,179
Number of Sequences: 60738
Number of extensions: 1872294
Number of successful extensions: 5217
Number of sequences better than 1.0e-05: 14
Number of HSP's better than 0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 5126
Number of HSP's gapped (non-prelim): 16
length of query: 712
length of database: 30,389,216
effective HSP length: 114
effective length of query: 598
effective length of database: 23,465,084
effective search space: 14032120232
effective search space used: 14032120232
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)