ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0277 good S KOG0293 Function unknown WD40 repeat-containing protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0277 89978 92128 717
(717 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YCL039w [S] KOG0293 WD40 repeat-containing protein 403 e-112
SPAC343.04c [S] KOG0293 WD40 repeat-containing protein 126 1e-28
At5g08560 [S] KOG0293 WD40 repeat-containing protein 116 1e-25
At5g43920 [S] KOG0293 WD40 repeat-containing protein 108 2e-23
Hs13376761 [S] KOG0293 WD40 repeat-containing protein 82 3e-15
At3g49660 [R] KOG0266 WD40 repeat-containing protein 55 5e-07
>YCL039w [S] KOG0293 WD40 repeat-containing protein
Length = 745
Score = 403 bits (1036), Expect = e-112
Identities = 263/736 (35%), Positives = 379/736 (50%), Gaps = 87/736 (11%)
Query: 48 FDRVQLTKLLIDALKQIGYEETAITLQKESGGILVESTHVKSLFSAIKEGRFYHCTLDLL 107
FD+ QLTKLLI LK++GY+ A L ESGG ES H+++ F IK G+F+ ++
Sbjct: 27 FDKKQLTKLLIHTLKELGYDSAANQLLLESGGYQNESNHIQTFFKLIKTGQFHLINWQIV 86
Query: 108 LQLPIFLESLELSGDLSHVELPQTKRNISTTIIDHFLAEYEKLGFVMKRL--SEFKDVDI 165
LP+ S S L + +P T +T++ DH L + + L +M + S D +I
Sbjct: 87 CSLPLAHSSPLRSEWLQRLLIP-TPTPATTSLFDHMLLQLQYLQQLMSSVNSSTCSDAEI 145
Query: 166 VKLTICVEMLVAIQTLAFSEILMSDRRMALE----------LLRLVIRPTISIWDTLLTL 215
L VE+++ + F E A LR +++ I IWD+LL
Sbjct: 146 ATLRNYVEIMILVNRQIFLEFFHPVTNSASHKGPHTALPVLYLRKILKNFIEIWDSLLV- 204
Query: 216 QTMKYDSEIQWQTGNDVMYSNSFSSFQPEHLLSQLSTLIVCGQNSNAAPFVTREATFEHI 275
ND + N + F PE L +LST + A + R+ + I
Sbjct: 205 -------------SND-QFLNEENIFNPETTLRELSTYLT-NPKLTAQLNLERDHLIDAI 249
Query: 276 AHFINPNDLVPRGRLMQLLKQAIQYQRSRDLLSFHIEDSSTGTKRSASSTYNLLQDNVTK 335
+ +I+PN+LVP+GRL+ LLKQAI+YQ+S+D+ + I+ + S NLLQDN +
Sbjct: 250 SKYIDPNELVPKGRLLHLLKQAIKYQQSQDIFNI-IDPDDDASFSSPPHRINLLQDNFSH 308
Query: 336 STQFQFDNIKTLNRNNDEIWFLQFSSDGRFLASASPSKKFERKIIIYDVKNNFEIYAICC 395
F KT+ DEIWFL FS +G++LASA+ I +YDV+ +F+IY C
Sbjct: 309 DLTVTFQEWKTIQDTTDEIWFLTFSPNGKYLASATSESSRGYFITVYDVEQDFKIYKTCV 368
Query: 396 ETRQSVLYLKFSPDNTKLIACSINSAAKIYDLNQLSPP----TYDGYLCEYDQLKPVASV 451
QSVLYL FSPD+ L+AC + IYD+N S P T L +L P+ S
Sbjct: 369 SLSQSVLYLMFSPDSRYLVACPFSEDVTIYDMNATSLPDASATDSFLLYPSTRLSPMDSF 428
Query: 452 ---FVTFPTTSDSSAISSNNTPASAET--MRLWCGDWFHDPELKDFIVLGSPDSDVIIYD 506
T+P ++SSA SS++ PA+A + R+WC D FH E ++V+GSPD + I++
Sbjct: 429 KLDTTTYPDDTESSA-SSSSRPANANSNQSRVWCCDAFHTAERAGWMVVGSPDREAIVHS 487
Query: 507 MKTA----TIFARISMTMGEDLKSS-----------------------------FPHVHD 533
+ T ++ R + +G D S FP VHD
Sbjct: 488 LTTKESLFSLKGRTCIALGHDENISGRKSIDPAKVLYKPTSSNGNWQYVEDDETFPRVHD 547
Query: 534 IKISSDDNDLIVMNNEKYIDVFDIS------TLKYCIKENATFVSPRKRRLLIGKRMTGM 587
+KIS DD +++M ++ IDV+D S L + F+ PR RL +GK MT +
Sbjct: 548 VKISYDDKYVLLMTHQGVIDVYDFSGFPSKEELSKQTVDPKNFLIPRIARLDVGKNMTCI 607
Query: 588 QFPDTS-----QCSPDPXXXXXXXXXIQNQELQLWDYQRDILIQRYIGQIQSNFIIRSCF 642
P + +Q+ ELQ+WDY+ +ILIQ+Y GQ Q +FIIRSCF
Sbjct: 608 SLPLNTTHQGFHRQQISESQHLVLVSLQDNELQMWDYKENILIQKYFGQKQQHFIIRSCF 667
Query: 643 GYYSNFIASGSEDGKIYLWDRFYGNIIGVIPAHS---ENSTSSQSKICNIVAWNPQDQTM 699
Y + + SGSEDGKIY+WDR GN++ V+ HS NST K CN+VA NP D+ M
Sbjct: 668 AYGNKLVMSGSEDGKIYIWDRIRGNLVSVLSGHSTVMSNSTKPMGKNCNVVASNPADKEM 727
Query: 700 FASGGDDGLVKVWRVS 715
FASGGDDG +K+W++S
Sbjct: 728 FASGGDDGKIKIWKIS 743
>SPAC343.04c [S] KOG0293 WD40 repeat-containing protein
Length = 507
Score = 126 bits (317), Expect = 1e-28
Identities = 105/447 (23%), Positives = 191/447 (42%), Gaps = 90/447 (20%)
Query: 267 TREATFEHIAHFINPNDLVPRGRLMQLLKQAIQYQRSRDLLSFHIEDSSTGTKRSASSTY 326
TR ++ +I+P L+P+ RL LL+QA YQ S + +H + +
Sbjct: 141 TRLDLLNQLSEYISPEILLPKRRLEHLLQQAKDYQVSSQV--YH----------NVLKNF 188
Query: 327 NLLQDNVTKSTQFQFDNIKTLNRNNDEIWFLQFSSDGRFLASASPSKKFERKIIIYDVKN 386
+ L D ++ + ++DE+W + +S +GR+LASAS K II+DV N
Sbjct: 189 SFLSDYKADPSELPTKEYHVFHDHSDEVWQISYSHNGRYLASASKDKT----AIIFDVVN 244
Query: 387 NFEIYAICCETRQSVLYLKFSPDNTKLIACSINSAAKIYDLNQLSPPTYDGYLCEYDQLK 446
++ + +V Y+++SPD+ L++CS + + ++D
Sbjct: 245 LKRVFRLIGHI-DTVAYIRWSPDDRYLLSCSCDKSVILWD-------------------- 283
Query: 447 PVASVFVTFPTTSDSSAISSNNTPASAETMRLWCGDWFHDPELKDFIVLGSPDSDVIIYD 506
A + + C W P+ FI GSPD + +
Sbjct: 284 ----------------AFTGEKLRDYKHGFSVSCCCWL--PDGLSFIT-GSPDCHITHWS 324
Query: 507 MKTATIFARISMTMGEDLKSSFPHVHDIKISSDDNDLIVMNNEKYIDVFDISTLKYCIKE 566
+ ++ ED+ +++D+ ++SD L ++ E+ I+ D Y ++
Sbjct: 325 LNGEILYK------WEDV-----NIYDMALTSDGTKLYIVGFEQLINAEDKHIAIYSVET 373
Query: 567 NATFVSPRKRRLLIGKRMTGMQFPDTSQCSPDPXXXXXXXXXIQNQELQLWDYQRDILIQ 626
+++ + ++T + S+ + ++ LWD + + +++
Sbjct: 374 RECI-----KKISLQSKVTSICLSKDSKYA---------LTNLEPHTTFLWDLEENRIVR 419
Query: 627 RYIGQIQSNFIIRSCFGYYSN-FIASGSEDGKIYLWDRFYGNIIGVIPAHSENSTSSQSK 685
+Y+G NF+I SCFG + F+ SGSED KI +W R G ++ + H K
Sbjct: 420 QYMGHKLGNFLIGSCFGGKDDTFVLSGSEDDKIRIWHRESGKLLATLSGHV--------K 471
Query: 686 ICNIVAWNPQDQTMFASGGDDGLVKVW 712
N VA+NP D FAS GDD V++W
Sbjct: 472 CVNYVAYNPVDPYQFASAGDDNTVRIW 498
>At5g08560 [S] KOG0293 WD40 repeat-containing protein
Length = 589
Score = 116 bits (290), Expect = 1e-25
Identities = 105/451 (23%), Positives = 192/451 (42%), Gaps = 97/451 (21%)
Query: 267 TREATFEHIAHFINPNDLVPRGRLMQLLKQAIQYQRSRDLLSFHIEDSSTGTKRSASSTY 326
+R E + + + ++P RL L++ ++ QR D FH + S
Sbjct: 201 SRSKVLEELQTLLPASVIIPEKRLECLVENSLHIQR--DSCVFH---------NTLDSDL 249
Query: 327 NLLQDNVTKSTQFQFDNIKTLNRNNDEIWFLQFSSDGRFLASASPSKKFERKIIIYDVK- 385
+L D+ Q + L + DE+WFLQFS +G++LAS+S ++ II+++
Sbjct: 250 SLYSDHQCGKHQIPSQTAQILESHTDEVWFLQFSHNGKYLASSSK----DQTAIIWEISA 305
Query: 386 -NNFEIYAICCETRQSVLYLKFSPDNTKLIACSINSAAKIYDLNQLSPPTYDGYLCEYDQ 444
+ + + V+ + +SPD+ +++ C + +D++ ++ E
Sbjct: 306 DGHISLKHTLVGHHKPVIAILWSPDDRQVLTCGAEEVIRRWDVDSGDCV----HMYEKGG 361
Query: 445 LKPVASVFVTFPTTSDSSAISSNNTPASAETMRLWCGDWFHDPELKDFIVLGSPDSDVII 504
+ P++ CG W+ D + I+ G D + +
Sbjct: 362 ISPIS------------------------------CG-WYPDGQ---GIIAGMTDRSICM 387
Query: 505 YDMKTATIFARISMTMGEDLKSSFPHVHDIKISSDDNDLIVMNNEKYIDVFDI-STLKYC 563
+D+ G+ + V DI ++ D L+ + + I +FD +T++
Sbjct: 388 WDLDGR----EKECWKGQRTQK----VSDIAMTDDGKWLVSVCKDSVISLFDREATVERL 439
Query: 564 IKENATFVSPRKRRLLIGKRMTGMQFPDTSQCSPDPXXXXXXXXXIQNQELQLWDYQRDI 623
I+E +T + ++ + NQE++LW+ + D
Sbjct: 440 IEEE--------------DMITSFSLSNDNK---------YILVNLLNQEIRLWNIEGDP 476
Query: 624 -LIQRYIGQIQSNFIIRSCFGYYSN-FIASGSEDGKIYLWDRFYGNIIGVIPAHSENSTS 681
++ RY G +S FIIRSCFG Y FIASGSED ++Y+W R G +I +P H
Sbjct: 477 KIVSRYKGHKRSRFIIRSCFGGYKQAFIASGSEDSQVYIWHRSTGKLIVELPGH------ 530
Query: 682 SQSKICNIVAWNPQDQTMFASGGDDGLVKVW 712
+ N V+W+P + M AS DDG +++W
Sbjct: 531 --AGAVNCVSWSPTNLHMLASASDDGTIRIW 559
>At5g43920 [S] KOG0293 WD40 repeat-containing protein
Length = 523
Score = 108 bits (271), Expect = 2e-23
Identities = 109/440 (24%), Positives = 187/440 (41%), Gaps = 106/440 (24%)
Query: 284 LVPRGRLMQLLKQAIQYQRSRDLLSFHIEDSSTGTKRSASSTYNLLQDNVTKSTQFQFDN 343
++P RL L++ A+ Q D +H ++ +L +D+ Q +
Sbjct: 169 VIPERRLEHLVETAVMDQI--DTCMYH----------NSCDAVSLYKDHCCGRDQIPSET 216
Query: 344 IKTLNRNNDEIWFLQFSSDGRFLASASPSKKFERKIIIYDV--KNNFEIYAICCETRQSV 401
++ L + +E+WF+QFS+ G++LA+AS + II+ V N E+ + V
Sbjct: 217 VQILVAHKNEVWFVQFSNSGKYLATASS----DCTAIIWKVLDDNKVELKHTLESHQNPV 272
Query: 402 LYLKFSPDNTKLIACSINSAAKIYDLNQLSPPTYDGYLCEYDQLKPVASVFVTFPTTSDS 461
++ +SPD+TKL+ C K++D++ G L TF +
Sbjct: 273 SFVSWSPDDTKLLTCGNAEVLKLWDVDT-------GVLRH------------TFGNNNTG 313
Query: 462 SAISSNNTPASAETMRLWCGDWFHDPELKDFIVLGS--PDSDVIIYDMKTATIFARISMT 519
+SS C WF D +V GS P+ ++++D T
Sbjct: 314 FTVSS-------------CA-WFPDSTR---LVCGSSDPERGIVMWD------------T 344
Query: 520 MGEDLKS----SFPHVHDIKISSDDNDLIVMNNEKYIDVFDIST-LKYCIKENATFVSPR 574
G ++K+ P V D+ ++ D +I + ++K I + ++ T ++ I E S
Sbjct: 345 DGNEIKAWRGTRIPKVVDLAVTPDGESMITVFSDKEIRILNLETKVERVISEEQPITS-- 402
Query: 575 KRRLLIGKRMTGMQFPDTSQCSPDPXXXXXXXXXIQNQELQLWDYQRDILIQ-RYIGQIQ 633
+ G F C QE+ LWD + ++ G Q
Sbjct: 403 -----LSISGDGKFFIVNLSC----------------QEIHLWDLAGEWKQPLKFSGHRQ 441
Query: 634 SNFIIRSCFGYY-SNFIASGSEDGKIYLWDRFYGNIIGVIPAHSENSTSSQSKICNIVAW 692
S ++IRSCFG S+FIASGSED ++Y+W+ + V+ HS N V+W
Sbjct: 442 SKYVIRSCFGGLDSSFIASGSEDSQVYIWNLKNTKPLEVLSGHSMT--------VNCVSW 493
Query: 693 NPQDQTMFASGGDDGLVKVW 712
NP++ M AS DD +++W
Sbjct: 494 NPKNPRMLASASDDQTIRIW 513
>Hs13376761 [S] KOG0293 WD40 repeat-containing protein
Length = 367
Score = 82.0 bits (201), Expect = 3e-15
Identities = 41/105 (39%), Positives = 61/105 (58%), Gaps = 9/105 (8%)
Query: 609 IQNQELQLWDYQRDILIQRYIGQIQSNFIIRSCFGYYS-NFIASGSEDGKIYLWDRFYGN 667
+ Q + LWD Q +L+++Y G Q + I SCFG ++ +FIASGSED K+Y+W +
Sbjct: 251 VATQGVHLWDLQDRVLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWHKRSEL 310
Query: 668 IIGVIPAHSENSTSSQSKICNIVAWNPQDQTMFASGGDDGLVKVW 712
I + H+ + N V+WNPQ +M AS DDG V++W
Sbjct: 311 PIAELTGHT--------RTVNCVSWNPQIPSMMASASDDGTVRIW 347
Score = 56.6 bits (135), Expect = 1e-07
Identities = 42/145 (28%), Positives = 74/145 (50%), Gaps = 14/145 (9%)
Query: 284 LVPRGRLMQLLKQAIQYQRSRDLLSFHIEDSSTGTKRSASSTYNLLQDNVTKSTQFQFDN 343
++P RL LL+QA++ QR R L +H +T + S +LL D+V QF
Sbjct: 1 MLPPRRLQTLLRQAVELQRDRCL--YH----NTKLDNNLDSV-SLLIDHVCSRRQFPCYT 53
Query: 344 IKTLNRNNDEIWFLQFSSDGRFLASASPSKKFERKIIIYDVKNNFEIYAICCETR---QS 400
+ L + +E+WF +FS+DG LA+ S + +II+ V + + +
Sbjct: 54 QQILTEHCNEVWFCKFSNDGTKLATGSK----DTTVIIWQVDPDTHLLKLLKTLEGHAYG 109
Query: 401 VLYLKFSPDNTKLIACSINSAAKIY 425
V Y+ +SPD+ L+AC + ++++
Sbjct: 110 VSYIAWSPDDNYLVACGPDDCSELW 134
>At3g49660 [R] KOG0266 WD40 repeat-containing protein
Length = 317
Score = 54.7 bits (130), Expect = 5e-07
Identities = 34/102 (33%), Positives = 52/102 (50%), Gaps = 11/102 (10%)
Query: 611 NQELQLWDYQRDILIQRYIGQIQSNFIIRSCFGYYSNFIASGSEDGKIYLWDRFYGNIIG 670
++ L+LWD + LI+ IG F + F SN I SGS D + +WD G +
Sbjct: 92 DKTLKLWDVETGSLIKTLIGHTNYAFCVN--FNPQSNMIVSGSFDETVRIWDVTTGKCLK 149
Query: 671 VIPAHSENSTSSQSKICNIVAWNPQDQTMFASGGDDGLVKVW 712
V+PAHS+ T+ V +N +D ++ S DGL ++W
Sbjct: 150 VLPAHSDPVTA--------VDFN-RDGSLIVSSSYDGLCRIW 182
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.134 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,657,234
Number of Sequences: 60738
Number of extensions: 1758642
Number of successful extensions: 7222
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 7177
Number of HSP's gapped (non-prelim): 23
length of query: 717
length of database: 30,389,216
effective HSP length: 114
effective length of query: 603
effective length of database: 23,465,084
effective search space: 14149445652
effective search space used: 14149445652
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)