ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0287 good OJ KOG2590 Posttranslational modification, protein turnover, chaperones RNA-binding protein LARP/SRO9 and related La domain proteins
r_klactIII0287 good OJ KOG2590 Translation, ribosomal structure and biogenesis RNA-binding protein LARP/SRO9 and related La domain proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0287 95408 93921 -496
(496 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YCL037c [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related L... 99 2e-20
YDR515w [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related L... 79 1e-14
Hs22049862 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and relate... 68 4e-11
Hs8922390 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related... 62 3e-09
7301667 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related L... 61 3e-09
SPAC1527.03 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and relat... 58 4e-08
CE28950 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related L... 57 5e-08
CE28663 [T] KOG2591 c-Mpl binding protein contains La domain 57 8e-08
At5g46250 [R] KOG1855 Predicted RNA-binding protein 55 2e-07
7292338 [T] KOG2591 c-Mpl binding protein contains La domain 52 2e-06
7298671 [A] KOG4213 RNA-binding protein La 51 5e-06
>YCL037c [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related La domain
proteins
Length = 466
Score = 98.6 bits (244), Expect = 2e-20
Identities = 90/329 (27%), Positives = 150/329 (45%), Gaps = 50/329 (15%)
Query: 179 RQTNKTSSSNGTNEKISVNGTTPASASGSSDITKNGYTEESNQADKRPETXXXXXXXXXX 238
R +K +SNG + K S N T AS++ SS+ + + N K+ +
Sbjct: 126 RSGSKNGASNGNSNK-SKNNKTAASSTSSSNANRKKKHHQHNA--KKQQQMKKDGFESAV 182
Query: 239 XXGISAPPSAETDGKKVESQQ--------------------RRFTPNSKPFYPRXXXXXX 278
S +++ +G+ + QQ R+F ++ P+
Sbjct: 183 GEEDSKDATSQENGQSTQQQQPPHHRNHHHSHHHNSNGPQRRKFHNSNNAGMPQNQGFPP 242
Query: 279 XXXXXXXXXXXXXXXXXXXXXXXSKYQRQRSYAPV--MYQQNYT--PSYVLVNEIVRQIQ 334
+ +Q P+ + QQ Y P + +N I RQI+
Sbjct: 243 QFKPYQGRNARNNNNNRSKYHNHFHHNQQHPQQPMVKLQQQFYPVQPVLMAINNIARQIE 302
Query: 335 YYFSIQNLSKDMFLKSQMNAQGYVPLALISRFHRMLNLSY-GDVGLILAALRELKNSENS 393
YYFS +NL+ D +L+S+++ G+ PL+LIS+F+R++N+S+ GD LILAALRE+ +E +
Sbjct: 303 YYFSEENLTVDNYLRSKLSKDGFAPLSLISKFYRVVNMSFGGDTNLILAALREIVANEAA 362
Query: 394 NVNIAKLT---EPFENVVG-----NPLFQYALSSKVWTADESISEPKSYDT-----VEFV 440
VN+A+ T + +NV G +PL +Y + SK W S P++++T E V
Sbjct: 363 TVNVAEGTLAAKEGDNVTGEAKEPSPLDKYFVRSKSW----SNWLPETFETEINIEKELV 418
Query: 441 SDELELFKIEPINPIIDSLPSFKPNSSTE 469
D L+ F I + +P + SSTE
Sbjct: 419 GDALDQFMIS-----LPPVPQQEEESSTE 442
>YDR515w [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related La domain
proteins
Length = 447
Score = 79.3 bits (194), Expect = 1e-14
Identities = 80/337 (23%), Positives = 143/337 (41%), Gaps = 64/337 (18%)
Query: 164 KKDSEGEKKATKKQDRQTNKTSSSNGTNEKISVNGTTPASASGS-SDITKNGYTEESNQA 222
KKD G+ +T + +N S N K++++ ++ A+A+G+ IT N + Q+
Sbjct: 123 KKDFNGQTNSTSEISNVSNLESKPLDANAKVNIHSSSGATANGNIKRITNNNNSTNGRQS 182
Query: 223 ------DKRPETXXXXXXXXXXXXGISAPPSAETDGKKVESQQRRFTPNSKPFYPRXXXX 276
+ + IS P + + + + + NS+ Y +
Sbjct: 183 RNYQNRNGKTRYNNNSRHSQAANNAISFPNNYQARPEYIPNASHWLNNNSRNSYKQL--- 239
Query: 277 XXXXXXXXXXXXXXXXXXXXXXXXXSKYQRQRSYAPVMYQQ--------NYTPSYVLVNE 328
S +++Q+ Y + YQQ + P + +
Sbjct: 240 -------------------------SYFRQQQYYNNINYQQQLQTPYYYSMEPIFKSIES 274
Query: 329 IVRQIQYYFSIQNLSKDMFLKSQMNA--QGYVPLALISRFHRMLNLSY-GDVGLILAALR 385
I QI++YFS +NL D FL+S+ G++P++LI +F+RM+NLS GD LILA++R
Sbjct: 275 IKNQIEFYFSEENLKTDEFLRSKFKKANDGFIPMSLIGKFYRMVNLSLGGDPNLILASMR 334
Query: 386 E-LKNSENSNVNIA--KLTEPFENVVG--NPLFQYALSSKVWTADESISEPKSYDTVEFV 440
E L++ E +++ IA + +N+ NPL Y + + W +E +
Sbjct: 335 EVLQHKETNHLEIALGSIEGAQKNMADDFNPLENYFIRRENW------AEYAMESNFDEN 388
Query: 441 SDELELFKIEPI-------NPIIDSLPSFKPNSSTEK 470
DE E + IE + N P+F P++ K
Sbjct: 389 DDETEKYNIEKLLGPNDLDNYSYMGYPNFFPSNENGK 425
>Hs22049862 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related La domain
proteins
Length = 891
Score = 67.8 bits (164), Expect = 4e-11
Identities = 34/80 (42%), Positives = 54/80 (67%), Gaps = 1/80 (1%)
Query: 324 VLVNEIVRQIQYYFSIQNLSKDMFLKSQMNAQGYVPLALISRFHRMLNLSYGDVGLILAA 383
+L + I RQI+YYFS+ NL +D FL+ +M+A G++P+ LI+ FHR+ L+ D+ LI AA
Sbjct: 197 LLKDYIKRQIEYYFSVDNLERDFFLRRKMDADGFLPITLIASFHRVQALT-TDISLIFAA 255
Query: 384 LRELKNSENSNVNIAKLTEP 403
L++ K E + + + EP
Sbjct: 256 LKDSKVVEIVDEKVRRREEP 275
>Hs8922390 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related La domain
proteins
Length = 328
Score = 61.6 bits (148), Expect = 3e-09
Identities = 34/88 (38%), Positives = 56/88 (63%), Gaps = 2/88 (2%)
Query: 317 QNYTPSYVLVNEIV-RQIQYYFSIQNLSKDMFLKSQMNAQGYVPLALISRFHRMLNLSYG 375
Q Y L+ E + RQI+YYFS++NL +D FL+ +M+ QG++P++LI+ F R+ L+
Sbjct: 12 QVYPVEEALLKEYIKRQIEYYFSVENLERDFFLRGKMDEQGFLPISLIAGFQRVQALT-T 70
Query: 376 DVGLILAALRELKNSENSNVNIAKLTEP 403
++ LIL AL++ E + + K EP
Sbjct: 71 NLNLILEALKDSTEVEIVDEKMRKEIEP 98
>7301667 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related La domain
proteins
Length = 1184
Score = 61.2 bits (147), Expect = 3e-09
Identities = 27/58 (46%), Positives = 45/58 (77%), Gaps = 1/58 (1%)
Query: 329 IVRQIQYYFSIQNLSKDMFLKSQMNAQGYVPLALISRFHRMLNLSYGDVGLILAALRE 386
I +Q++YYFS+ NL+ D FL+ +M+ +GY+P+ LI+ FHR+L L+ DV +I+ A++E
Sbjct: 477 IKKQVEYYFSVDNLTGDFFLRRKMDPEGYIPVTLIASFHRVLALT-TDVAVIVNAIKE 533
>SPAC1527.03 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related La domain
proteins
Length = 475
Score = 57.8 bits (138), Expect = 4e-08
Identities = 27/57 (47%), Positives = 42/57 (73%), Gaps = 1/57 (1%)
Query: 329 IVRQIQYYFSIQNLSKDMFLKSQMNAQGYVPLALISRFHRMLNLSYGDVGLILAALR 385
+ Q++YYFSI+NL KDMFL+ M+ +GYVPLA ++ F+R+ + S D+ L+ AA +
Sbjct: 329 LTSQLEYYFSIENLCKDMFLRKHMDDEGYVPLAFLASFNRIKSFS-TDLNLLHAACK 384
>CE28950 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related La domain
proteins
Length = 1109
Score = 57.4 bits (137), Expect = 5e-08
Identities = 28/56 (50%), Positives = 42/56 (75%), Gaps = 1/56 (1%)
Query: 331 RQIQYYFSIQNLSKDMFLKSQMNAQGYVPLALISRFHRMLNLSYGDVGLILAALRE 386
+QI+YYFS +NL KD FL+ +M +GY+P+ALI+ F R+ +L+ D LIL AL++
Sbjct: 526 KQIEYYFSEENLQKDFFLRRKMGPEGYLPVALIASFPRVRSLT-EDYSLILEALKD 580
>CE28663 [T] KOG2591 c-Mpl binding protein contains La domain
Length = 692
Score = 56.6 bits (135), Expect = 8e-08
Identities = 32/76 (42%), Positives = 48/76 (63%), Gaps = 9/76 (11%)
Query: 332 QIQYYFSIQNLSKDMFLKSQMNAQGYVPLALISRFHRMLNLSYGDVGLILAALRELKNSE 391
Q++YYFS +NLS D +LK QM++ YVP+ +++ F +++ L+ DV LI+ AL+E N E
Sbjct: 108 QLEYYFSRENLSSDRYLKCQMDSDNYVPINVLAGFPKIMRLT-TDVDLIVEALKESTNVE 166
Query: 392 NSNVNIAKLTEPFENV 407
L E FE V
Sbjct: 167 --------LDEKFEKV 174
>At5g46250 [R] KOG1855 Predicted RNA-binding protein
Length = 411
Score = 55.1 bits (131), Expect = 2e-07
Identities = 32/77 (41%), Positives = 48/77 (61%), Gaps = 3/77 (3%)
Query: 312 PVMYQQNYTPSYVLVNEIVRQIQYYFSIQNLSKDMFLKSQM--NAQGYVPLALISRFHRM 369
PV P L +I+RQ++YYFS +NL D FL + M N +G+VP++ I+ FH+M
Sbjct: 79 PVETDGVVVPIDELNQKIIRQVEYYFSDENLPTDKFLLNAMKRNKKGFVPISTIATFHKM 138
Query: 370 LNLSYGDVGLILAALRE 386
L+ D LI++AL+E
Sbjct: 139 KKLT-RDHALIVSALKE 154
>7292338 [T] KOG2591 c-Mpl binding protein contains La domain
Length = 1521
Score = 52.0 bits (123), Expect = 2e-06
Identities = 25/61 (40%), Positives = 40/61 (64%), Gaps = 1/61 (1%)
Query: 329 IVRQIQYYFSIQNLSKDMFLKSQMNAQGYVPLALISRFHRMLNLSYGDVGLILAALRELK 388
+ Q++YYFS +NL+ D +L SQM++ YVP+ ++RF+ + L+ D+ LI LRE
Sbjct: 262 LATQLEYYFSRENLANDTYLLSQMDSDQYVPIYTVARFNLVRKLT-NDINLITEVLRESP 320
Query: 389 N 389
N
Sbjct: 321 N 321
>7298671 [A] KOG4213 RNA-binding protein La
Length = 390
Score = 50.8 bits (120), Expect = 5e-06
Identities = 30/73 (41%), Positives = 48/73 (65%), Gaps = 6/73 (8%)
Query: 329 IVRQIQYYFSIQNLSKDMFLKSQM--NAQGYVPLALISRFHRMLNLSYGDVGLILAALRE 386
I+RQ++YYF NL++D FL+ Q+ N G+VPL+++ F R+ +LS D+ I+AAL +
Sbjct: 54 IIRQVEYYFGDANLNRDKFLREQIGKNEDGWVPLSVLVTFKRLASLS-TDLSEIVAALNK 112
Query: 387 LKNSENSNVNIAK 399
SE V I++
Sbjct: 113 ---SEEGLVEISE 122
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.307 0.125 0.342
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,301,742
Number of Sequences: 60738
Number of extensions: 700484
Number of successful extensions: 2937
Number of sequences better than 1.0e-05: 11
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2918
Number of HSP's gapped (non-prelim): 18
length of query: 496
length of database: 30,389,216
effective HSP length: 110
effective length of query: 386
effective length of database: 23,708,036
effective search space: 9151301896
effective search space used: 9151301896
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)