ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0332 good E KOG2697 Amino acid transport and metabolism Histidinol dehydrogenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0332 111183 108799 -795
(795 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YCL030c_2 [E] KOG2697 Histidinol dehydrogenase 698 0.0
SPBC1711.13 [E] KOG2697 Histidinol dehydrogenase 431 e-120
YCL030c_1 [E] KOG4311 Histidinol dehydrogenase 383 e-106
At5g63890 [E] KOG2697 Histidinol dehydrogenase 380 e-105
SPBC29A3.02c [E] KOG4311 Histidinol dehydrogenase 221 3e-57
At1g31860 [E] KOG4311 Histidinol dehydrogenase 89 3e-17
>YCL030c_2 [E] KOG2697 Histidinol dehydrogenase
Length = 428
Score = 698 bits (1801), Expect = 0.0
Identities = 346/428 (80%), Positives = 385/428 (89%)
Query: 368 KAVTRPIQKTAEIMNLVNPIIENVIKNGDKALVELTAKFDGVQLETPVLEAPYPEEYLDG 427
KA++RPIQKT+EIM+LVNPIIENV G+ AL+E T KFDGV+L PVL AP+PEEY +G
Sbjct: 1 KALSRPIQKTSEIMHLVNPIIENVRDKGNSALLEYTEKFDGVKLSNPVLNAPFPEEYFEG 60
Query: 428 LTDELRDALDLSIENVKKFHAAQMQSETLDVETQPGVVCSRFPRPIEKVGLYIPGGTAIL 487
LT+E+++ALDLSIENV+KFHAAQ+ +ETL+VETQPGV+CSRFPRPIEKVGLYIPGGTAIL
Sbjct: 61 LTEEMKEALDLSIENVRKFHAAQLPTETLEVETQPGVLCSRFPRPIEKVGLYIPGGTAIL 120
Query: 488 PSTALMLGVPAQVAGCKEIVFASPPRKSDGRVSPEVVYVASKVGASKIVLXXXXXXXXXX 547
PSTALMLGVPAQVA CKEIVFASPPRKSDG+VSPEVVYVA KVGASKIVL
Sbjct: 121 PSTALMLGVPAQVAQCKEIVFASPPRKSDGKVSPEVVYVAEKVGASKIVLAGGAQAVAAM 180
Query: 548 XXXTESVPKVDKILGPGNQFVTAAKMYVQNDTQALCSIDMPAGPSEVLVICDEEADVDFV 607
TE++PKVDKILGPGNQFVTAAKMYVQNDTQALCSIDMPAGPSEVLVI DE+ADVDFV
Sbjct: 181 AYGTETIPKVDKILGPGNQFVTAAKMYVQNDTQALCSIDMPAGPSEVLVIADEDADVDFV 240
Query: 608 ASDLLSQAEHGIDSQVILVGVSLSDSKIEALQNAVHEQAMQLPRVDIVRKCIAHSSIILC 667
ASDLLSQAEHGIDSQVILVGV+LS+ KI+ +Q+AVH QA+QLPRVDIVRKCIAHS+I+LC
Sbjct: 241 ASDLLSQAEHGIDSQVILVGVNLSEKKIQEIQDAVHNQALQLPRVDIVRKCIAHSTIVLC 300
Query: 668 DSYEEAFKMSNQYAPEHLILQISNAEDYVKDVDHAGSIFVGAYTPESCGDYSSGTNHTLP 727
D YEEA +MSNQYAPEHLILQI+NA DYVK VD+AGS+FVGAYTPESCGDYSSGTNHTLP
Sbjct: 301 DGYEEALEMSNQYAPEHLILQIANANDYVKLVDNAGSVFVGAYTPESCGDYSSGTNHTLP 360
Query: 728 TYGYARQYSGVNTATFQKFITSQVVTPVGLEHIGHAVMSVAKVEGLDAHRNAVKIRMSKL 787
TYGYARQYSG NTATFQKFIT+Q +TP GLE+IG AVM VAK EGLD HRNAVKIRMSKL
Sbjct: 361 TYGYARQYSGANTATFQKFITAQNITPEGLENIGRAVMCVAKKEGLDGHRNAVKIRMSKL 420
Query: 788 GLLPSGFE 795
GL+P F+
Sbjct: 421 GLIPKDFQ 428
>SPBC1711.13 [E] KOG2697 Histidinol dehydrogenase
Length = 439
Score = 431 bits (1109), Expect = e-120
Identities = 212/420 (50%), Positives = 305/420 (72%), Gaps = 3/420 (0%)
Query: 368 KAVTRPIQKTAEIMNLVNPIIENVIKNGDKALVELTAKFDGVQLETPVLEAPYPEEYLDG 427
+ + RPIQ T +I +V PIIE+V G+ +L++ +KF+ VQL++ VL+AP+ ++ +
Sbjct: 23 RLLARPIQNTQKIRTIVQPIIEDVKSRGEASLIDYASKFEKVQLKSAVLKAPFDDDLMK- 81
Query: 428 LTDELRDALDLSIENVKKFHAAQMQSETLDVETQPGVVCSRFPRPIEKVGLYIPGGTAIL 487
++ +++ +D++ N+ FH++Q++ T+ V+T GVVC R RPI +VGLYIPGGTA+L
Sbjct: 82 ISPMIKEDIDIAFNNIFAFHSSQLRP-TIAVQTMRGVVCQRMSRPINRVGLYIPGGTAVL 140
Query: 488 PSTALMLGVPAQVAGCKEIVFASPPRKSDGRVSPEVVYVASKVGASKIVLXXXXXXXXXX 547
PSTALMLGVPA+VAGC +V ++P RK DG V+PE+VY+A+K+GA I+L
Sbjct: 141 PSTALMLGVPAKVAGCPHVVISTPVRK-DGTVAPEIVYIANKIGAEAIILAGGAQAIAAM 199
Query: 548 XXXTESVPKVDKILGPGNQFVTAAKMYVQNDTQALCSIDMPAGPSEVLVICDEEADVDFV 607
VPKV+KI GPGNQFVTAAKM+VQND AL +ID+PAGPSEVLVI DE + + V
Sbjct: 200 AYGISGVPKVNKIFGPGNQFVTAAKMHVQNDYGALVAIDLPAGPSEVLVIADETCNPESV 259
Query: 608 ASDLLSQAEHGIDSQVILVGVSLSDSKIEALQNAVHEQAMQLPRVDIVRKCIAHSSIILC 667
A DLLSQAEHG+DSQ+IL+ VSLS + +Q A+++ A++L R I++ I S I+
Sbjct: 260 ALDLLSQAEHGLDSQIILLTVSLSPEMFDRIQKAINDHALRLSRSYIIKHAIKKSVIVQV 319
Query: 668 DSYEEAFKMSNQYAPEHLILQISNAEDYVKDVDHAGSIFVGAYTPESCGDYSSGTNHTLP 727
D+ ++AF+ SN Y PEHL+L + NA Y+ +D+AGS+FVG ++P S GDY+SGTNHTLP
Sbjct: 320 DNVDQAFEWSNLYGPEHLVLHLKNASSYIPKIDNAGSVFVGPWSPVSMGDYASGTNHTLP 379
Query: 728 TYGYARQYSGVNTATFQKFITSQVVTPVGLEHIGHAVMSVAKVEGLDAHRNAVKIRMSKL 787
TYGYA YSGV+T +F K+IT+Q +T G++ +G V+ +A++EGL AH +AV++R +L
Sbjct: 380 TYGYASSYSGVSTDSFLKYITTQELTEEGIQRLGPTVIRLAELEGLTAHADAVRVRGVRL 439
>YCL030c_1 [E] KOG4311 Histidinol dehydrogenase
Length = 371
Score = 383 bits (983), Expect = e-106
Identities = 201/371 (54%), Positives = 265/371 (71%), Gaps = 5/371 (1%)
Query: 1 MLPVVPVFNAVNALK-EKTYLYLSSQLVLDGKDMTKDDILEFVQNSHGQNISVLLKDAKF 59
+LP++P+ + + + +K Y+ L Q++LDG ++ ++IL+F + +++ L KF
Sbjct: 2 VLPILPLIDDLASWNSKKEYVSLVGQVLLDGSSLSNEEILQFSKEEEVPLVALSLPSGKF 61
Query: 60 EDDDLIVLLNNGVVTLFIDSDDY--AAHLVE-IGVPSIRLTLLKDGAYQFSFGQIQEIQQ 116
DD++I LNNGV +LFI S D A HLVE + VP R+ + ++G + F Q+ Q
Sbjct: 62 SDDEIIAFLNNGVSSLFIASQDAKTAEHLVEQLNVPKERVVVEENGVFSNQFMVKQKFSQ 121
Query: 117 SQLVKASEISLETFTNSVLSGMKTDRPDGLYTTLVVDENERSLGLVYSNKESVSLAIETQ 176
++V ++S + T VL ++TDRPDGLYTTLVVD+ ER LGLVYS+K+S++ AI+
Sbjct: 122 DKIVSIKKLSKDMLTKEVLGEVRTDRPDGLYTTLVVDQYERCLGLVYSSKKSIAKAIDLG 181
Query: 177 TGIYFSRSRNEIWRKGATSGNVQKLLSIELDCDGDALKFVVRQGGSGSFCHLETESCFGN 236
G+Y+SRSRNEIW KG TSGN QKLL I DCD DALKF+V Q G FCHLET SCFG
Sbjct: 182 RGVYYSRSRNEIWIKGETSGNGQKLLQISTDCDSDALKFIVEQENVG-FCHLETMSCFGE 240
Query: 237 FRHGLYGLQKLLQERLLNAPEGSYTKRLFNDSDLLTAKIKEEAEELTEAVDKKDIAWECA 296
F+HGL GL+ LL++RL +APE SYT+RLFNDS LL AKIKEEAEELTEA KK+++WE A
Sbjct: 241 FKHGLVGLESLLKQRLQDAPEESYTRRLFNDSALLDAKIKEEAEELTEAKGKKELSWEAA 300
Query: 297 DLFYFAMARLVANGVSLEDVERNLNTKHLKITRRKGDAKPKFLKKEPVAVHEEDGKIVLN 356
DLFYFA+A+LVAN VSL+DVE NLN KHLK+TRRKGDAKPKF+ + + G I L+
Sbjct: 301 DLFYFALAKLVANDVSLKDVENNLNMKHLKVTRRKGDAKPKFVGQPKAEEEKLTGPIHLD 360
Query: 357 VVSASDKAAVE 367
VV ASDK V+
Sbjct: 361 VVKASDKVGVQ 371
>At5g63890 [E] KOG2697 Histidinol dehydrogenase
Length = 466
Score = 380 bits (975), Expect = e-105
Identities = 204/430 (47%), Positives = 278/430 (64%), Gaps = 6/430 (1%)
Query: 358 VSASDKAAVEKAVTRPIQKTAEIMNLVNPIIENVIKNGDKALVELTAKFDGVQLETPVLE 417
+S + V+ +RP + I VNPII+ V NGD A+ E T +FD VQL V +
Sbjct: 37 LSELSSSQVDSLKSRPRIDFSSIFATVNPIIDAVRSNGDNAVKEYTERFDKVQLNKVVED 96
Query: 418 APYPEEYLDGLTDELRDALDLSIENVKKFHAAQMQSETLDVETQPGVVCSRFPRPIEKVG 477
E + L +++A D++ +N+ FH AQ +E VE GV C R R I VG
Sbjct: 97 MS--ELSVPELDSNVKEAFDVAYDNIYAFHLAQKSTEK-SVENMKGVRCKRVSRSIGSVG 153
Query: 478 LYIPGGTAILPSTALMLGVPAQVAGCKEIVFASPPRKSDGRVSPEVVYVASKVGASKIVL 537
LY+PGGTA+LPSTALML +PAQ+AGCK +V A+PP K DG + EV+Y A + G + I+
Sbjct: 154 LYVPGGTAVLPSTALMLAIPAQIAGCKTVVLATPPSK-DGSICKEVLYCAKRAGVTHILK 212
Query: 538 XXXXXXXXXXXXXTESVPKVDKILGPGNQFVTAAKMYVQNDTQALCSIDMPAGPSEVLVI 597
T+S PKV+KI GPGNQ+VTAAKM +QN ++A+ SIDMPAGPSEVLVI
Sbjct: 213 AGGAQAIAAMAWGTDSCPKVEKIFGPGNQYVTAAKMILQN-SEAMVSIDMPAGPSEVLVI 271
Query: 598 CDEEADVDFVASDLLSQAEHGIDSQVILVGVSLSDSKIEALQNAVHEQAMQLPRVDIVRK 657
DE A ++A+DLLSQAEHG DSQV+LV V S + A++ + +Q LPR + K
Sbjct: 272 ADEHASPVYIAADLLSQAEHGPDSQVVLVVVGDSVD-LNAIEEEIAKQCKSLPRGEFASK 330
Query: 658 CIAHSSIILCDSYEEAFKMSNQYAPEHLILQISNAEDYVKDVDHAGSIFVGAYTPESCGD 717
++HS + EA SN YAPEHLI+ + +AE + +++AGS+F+G +TPES GD
Sbjct: 331 ALSHSFTVFARDMIEAISFSNLYAPEHLIINVKDAEKWEGLIENAGSVFIGPWTPESVGD 390
Query: 718 YSSGTNHTLPTYGYARQYSGVNTATFQKFITSQVVTPVGLEHIGHAVMSVAKVEGLDAHR 777
Y+SGTNH LPTYGYAR YSGV+ +F KF+T Q +T GL ++G V ++A++EGLDAH+
Sbjct: 391 YASGTNHVLPTYGYARMYSGVSLDSFLKFMTVQSLTEEGLRNLGPYVATMAEIEGLDAHK 450
Query: 778 NAVKIRMSKL 787
AV +R+ +
Sbjct: 451 RAVTLRLKDI 460
>SPBC29A3.02c [E] KOG4311 Histidinol dehydrogenase
Length = 417
Score = 221 bits (564), Expect = 3e-57
Identities = 120/220 (54%), Positives = 155/220 (69%), Gaps = 3/220 (1%)
Query: 122 ASEISLETFTNSVLSGMKTDRPDGLYTTLVVDENERSLGLVYSNKESVSLAIETQTGIYF 181
A E + + +L TDR DGL++TLVV+E +LGLVYS+KESV+ +++T TG+Y
Sbjct: 187 AEEPKKLSLADLILISANTDREDGLFSTLVVNELGIALGLVYSSKESVAESLKTGTGVYQ 246
Query: 182 SRSRNEIWRKGATSGNVQKLLSIELDCDGDALKFVVRQGGSGSFCHLETESCFGNFRHGL 241
SR R +W KGA+SG VQ L+ I++DCD D L+FVV Q G G FCHL+T CFG GL
Sbjct: 247 SRKRG-LWYKGASSGAVQHLIHIDVDCDEDCLRFVVYQTGKG-FCHLDTLHCFGQ-ASGL 303
Query: 242 YGLQKLLQERLLNAPEGSYTKRLFNDSDLLTAKIKEEAEELTEAVDKKDIAWECADLFYF 301
L+K L +R NAPEGSYT RLF+D LL AKI EEAEEL +A K+++ WE ADL YF
Sbjct: 304 CQLEKTLIDRKNNAPEGSYTARLFSDPKLLRAKIMEEAEELCDATTKENVIWEMADLMYF 363
Query: 302 AMARLVANGVSLEDVERNLNTKHLKITRRKGDAKPKFLKK 341
A+ R V +GVSL D+ R+L+ KH K+TRRKGDAK + +K
Sbjct: 364 AITRCVGSGVSLNDISRHLDLKHRKVTRRKGDAKVAWQEK 403
>At1g31860 [E] KOG4311 Histidinol dehydrogenase
Length = 281
Score = 89.0 bits (219), Expect = 3e-17
Identities = 72/241 (29%), Positives = 123/241 (50%), Gaps = 33/241 (13%)
Query: 106 FSFGQIQEIQQSQLVKA----SEISLETFTNSVLSGMKTDRPDGLYTTLVVDENERSLGL 161
+SF + +S +V A I+L+ +++L +K D GL + + + ++ +
Sbjct: 23 YSFRDTKLRSRSNVVFACNDNKNIALQAKVDNLLDRIKWD-DKGLAVAIAQNVDTGAVLM 81
Query: 162 V-YSNKESVSLAIETQTGIYFSRSRNEIWRKGATSGNVQKLLSIELDCDGDALKFVVRQG 220
+ N+E++S I ++ +FSRSR+ +W KG TS N +L + +DCD D++ ++
Sbjct: 82 QGFVNREALSTTISSRKATFFSRSRSTLWTKGETSNNFINILDVYVDCDRDSIIYLGTP- 140
Query: 221 GSGSFCHLETESCF--------------GN--FRHGLYGLQKLLQERLLNA---PEG--S 259
G CH E+C+ GN LY L+ ++ +R + EG S
Sbjct: 141 -DGPTCHTGEETCYYTSVFDQLNNDEASGNKLALTTLYSLESIISKRKEESTVPQEGKPS 199
Query: 260 YTKRLFNDSDLLTAKIKEEAEELTEAV-DKKDIA---WECADLFYFAMARLVANGVSLED 315
+T+RL D LL +KI+EEA+EL + D ++++ E AD+ Y AM L GV +ED
Sbjct: 200 WTRRLLTDDALLCSKIREEADELCRTLEDNEEVSRTPSEMADVLYHAMVLLSKRGVKMED 259
Query: 316 V 316
V
Sbjct: 260 V 260
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.134 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,596,671
Number of Sequences: 60738
Number of extensions: 1976592
Number of successful extensions: 5176
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 5155
Number of HSP's gapped (non-prelim): 7
length of query: 795
length of database: 30,389,216
effective HSP length: 114
effective length of query: 681
effective length of database: 23,465,084
effective search space: 15979722204
effective search space used: 15979722204
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)