ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0398 check: MH D KOG0588 Cell cycle control, cell division, chromosome partitioning Serine/threonine protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0398 128119 131454 1112
(1112 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR507c [D] KOG0588 Serine/threonine protein kinase 986 0.0
YCL024w [T] KOG0583 Serine/threonine protein kinase 752 0.0
YKL101w [D] KOG0588 Serine/threonine protein kinase 378 e-104
CE28218 [D] KOG0588 Serine/threonine protein kinase 274 5e-73
7294217 [D] KOG0588 Serine/threonine protein kinase 266 2e-70
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 265 2e-70
At3g01090 [T] KOG0583 Serine/threonine protein kinase 265 4e-70
At3g29160 [T] KOG0583 Serine/threonine protein kinase 261 4e-69
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 253 9e-67
At5g39440 [T] KOG0583 Serine/threonine protein kinase 251 4e-66
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 243 2e-63
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 242 3e-63
7290150 [T] KOG0583 Serine/threonine protein kinase 241 6e-63
YDR477w [T] KOG0583 Serine/threonine protein kinase 233 1e-60
CE28643 [T] KOG0583 Serine/threonine protein kinase 231 6e-60
CE07458 [T] KOG0583 Serine/threonine protein kinase 231 6e-60
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 222 2e-57
At4g24400 [T] KOG0583 Serine/threonine protein kinase 221 6e-57
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 220 8e-57
At2g26980 [T] KOG0583 Serine/threonine protein kinase 220 8e-57
At5g35410 [T] KOG0583 Serine/threonine protein kinase 219 1e-56
CE23838 [R] KOG0586 Serine/threonine protein kinase 219 2e-56
CE27768 [R] KOG0586 Serine/threonine protein kinase 216 1e-55
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 214 5e-55
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 214 5e-55
At1g30270 [T] KOG0583 Serine/threonine protein kinase 214 6e-55
At2g30360 [T] KOG0583 Serine/threonine protein kinase 214 8e-55
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 213 2e-54
CE00847 [T] KOG0583 Serine/threonine protein kinase 213 2e-54
At1g48260 [T] KOG0583 Serine/threonine protein kinase 212 2e-54
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 211 7e-54
At2g25090 [T] KOG0583 Serine/threonine protein kinase 211 7e-54
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 210 9e-54
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 210 1e-53
7302570 [R] KOG0586 Serine/threonine protein kinase 209 3e-53
At5g10930 [T] KOG0583 Serine/threonine protein kinase 208 3e-53
7299438 [R] KOG0586 Serine/threonine protein kinase 208 3e-53
7299437 [R] KOG0586 Serine/threonine protein kinase 208 3e-53
At5g25110 [T] KOG0583 Serine/threonine protein kinase 208 4e-53
At5g45820 [T] KOG0583 Serine/threonine protein kinase 207 6e-53
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 206 1e-52
At5g01810 [T] KOG0583 Serine/threonine protein kinase 205 3e-52
At1g29230 [T] KOG0583 Serine/threonine protein kinase 205 3e-52
At1g01140 [T] KOG0583 Serine/threonine protein kinase 204 5e-52
At3g17510 [T] KOG0583 Serine/threonine protein kinase 204 6e-52
7302464 [R] KOG0586 Serine/threonine protein kinase 204 6e-52
At2g34180 [T] KOG0583 Serine/threonine protein kinase 200 9e-51
At5g01820 [T] KOG0583 Serine/threonine protein kinase 200 1e-50
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 198 3e-50
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 198 3e-50
At5g45810 [T] KOG0583 Serine/threonine protein kinase 197 6e-50
At4g30960 [T] KOG0583 Serine/threonine protein kinase 197 6e-50
At4g14580 [T] KOG0583 Serine/threonine protein kinase 197 8e-50
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 197 1e-49
CE17284 [T] KOG0583 Serine/threonine protein kinase 197 1e-49
At4g18700 [T] KOG0583 Serine/threonine protein kinase 197 1e-49
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 196 1e-49
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 195 3e-49
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 195 4e-49
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 194 6e-49
At3g23000 [T] KOG0583 Serine/threonine protein kinase 192 2e-48
7290249 [R] KOG0586 Serine/threonine protein kinase 192 2e-48
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 192 2e-48
At5g57630 [T] KOG0583 Serine/threonine protein kinase 192 2e-48
At5g07070 [T] KOG0583 Serine/threonine protein kinase 191 4e-48
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 190 9e-48
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 189 3e-47
At2g38490 [T] KOG0583 Serine/threonine protein kinase 188 5e-47
YPL141c [T] KOG0583 Serine/threonine protein kinase 187 8e-47
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 187 8e-47
At5g58380 [T] KOG0583 Serine/threonine protein kinase 186 2e-46
CE16081 [T] KOG0583 Serine/threonine protein kinase 182 2e-45
YDR122w [T] KOG0583 Serine/threonine protein kinase 182 3e-45
YLR096w [T] KOG0583 Serine/threonine protein kinase 182 3e-45
YOR233w [T] KOG0583 Serine/threonine protein kinase 181 6e-45
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 181 7e-45
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 180 1e-44
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 180 1e-44
CE28479 [T] KOG0583 Serine/threonine protein kinase 180 1e-44
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 178 4e-44
At4g40010 [T] KOG0583 Serine/threonine protein kinase 178 4e-44
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 177 6e-44
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 177 8e-44
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 176 2e-43
7303211 [T] KOG4717 Serine/threonine protein kinase 175 4e-43
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 172 2e-42
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 172 3e-42
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 171 8e-42
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 170 1e-41
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 169 2e-41
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 168 4e-41
CE21025 [D] KOG0580 Serine/threonine protein kinase 168 4e-41
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 168 4e-41
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 168 5e-41
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 167 6e-41
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 166 1e-40
7297080 [T] KOG0583 Serine/threonine protein kinase 166 1e-40
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 166 2e-40
CE24761 [D] KOG0580 Serine/threonine protein kinase 164 5e-40
YPL150w [T] KOG0583 Serine/threonine protein kinase 164 9e-40
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 163 2e-39
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 162 2e-39
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 162 3e-39
At5g63650 [T] KOG0583 Serine/threonine protein kinase 162 4e-39
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 161 5e-39
At4g33950 [T] KOG0583 Serine/threonine protein kinase 161 6e-39
At1g60940 [T] KOG0583 Serine/threonine protein kinase 161 6e-39
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 160 8e-39
At1g10940 [T] KOG0583 Serine/threonine protein kinase 160 8e-39
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 160 1e-38
At1g78290 [T] KOG0583 Serine/threonine protein kinase 160 1e-38
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 159 2e-38
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 159 2e-38
At5g66880 [T] KOG0583 Serine/threonine protein kinase 159 2e-38
At2g45490 [D] KOG0580 Serine/threonine protein kinase 159 2e-38
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 159 3e-38
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 159 3e-38
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 158 4e-38
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 158 4e-38
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 158 4e-38
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 158 5e-38
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 158 5e-38
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 158 5e-38
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 158 5e-38
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 158 5e-38
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 158 5e-38
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 158 5e-38
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 158 5e-38
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 158 5e-38
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 158 5e-38
At5g08590 [T] KOG0583 Serine/threonine protein kinase 158 5e-38
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 158 5e-38
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 157 7e-38
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 157 7e-38
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 157 1e-37
CE18454 [T] KOG4717 Serine/threonine protein kinase 156 1e-37
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 155 3e-37
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 155 3e-37
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 155 3e-37
At2g23030 [T] KOG0583 Serine/threonine protein kinase 155 3e-37
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 155 4e-37
At3g50500 [T] KOG0583 Serine/threonine protein kinase 154 6e-37
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 154 6e-37
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 154 7e-37
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 154 7e-37
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 154 7e-37
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 153 2e-36
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 153 2e-36
YPL209c [D] KOG0580 Serine/threonine protein kinase 152 2e-36
7296128 [T] KOG0583 Serine/threonine protein kinase 152 2e-36
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 152 3e-36
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 152 3e-36
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 152 4e-36
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 151 5e-36
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 150 1e-35
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 149 2e-35
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 149 2e-35
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 149 2e-35
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 149 3e-35
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 148 5e-35
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 148 5e-35
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 148 5e-35
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 148 5e-35
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 148 5e-35
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 148 5e-35
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 147 7e-35
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 147 7e-35
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 147 7e-35
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 147 9e-35
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 147 1e-34
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 146 2e-34
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 146 2e-34
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 146 2e-34
Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 146 2e-34
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 146 2e-34
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 146 2e-34
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 145 3e-34
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 145 3e-34
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 145 3e-34
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 145 3e-34
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 145 3e-34
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 145 3e-34
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 145 3e-34
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 145 5e-34
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 145 5e-34
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 145 5e-34
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 144 6e-34
7299793 [T] KOG0583 Serine/threonine protein kinase 144 6e-34
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 144 8e-34
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 144 8e-34
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 144 8e-34
7300413 [T] KOG0583 Serine/threonine protein kinase 144 8e-34
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 144 1e-33
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 143 1e-33
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 143 2e-33
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 143 2e-33
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 143 2e-33
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 143 2e-33
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 142 2e-33
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 142 3e-33
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 142 4e-33
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 142 4e-33
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 142 4e-33
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 142 4e-33
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 142 4e-33
7299536 [D] KOG0580 Serine/threonine protein kinase 141 5e-33
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 141 7e-33
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 140 8e-33
At4g32830 [D] KOG0580 Serine/threonine protein kinase 140 1e-32
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 140 1e-32
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 140 1e-32
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 139 2e-32
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 139 2e-32
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 139 2e-32
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 139 2e-32
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 139 2e-32
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 139 2e-32
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 139 3e-32
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 139 3e-32
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 139 3e-32
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 139 3e-32
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 138 4e-32
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 138 4e-32
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 138 4e-32
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 138 4e-32
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 138 6e-32
At2g25880 [D] KOG0580 Serine/threonine protein kinase 138 6e-32
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 138 6e-32
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 137 7e-32
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 137 9e-32
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 137 9e-32
7300106 [T] KOG0690 Serine/threonine protein kinase 137 9e-32
CE02604 [T] KOG0695 Serine/threonine protein kinase 137 1e-31
7300778 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 137 1e-31
CE17343 [T] KOG0583 Serine/threonine protein kinase 136 2e-31
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 136 2e-31
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 136 2e-31
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 136 2e-31
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 135 3e-31
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 135 3e-31
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 135 3e-31
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 135 3e-31
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 135 3e-31
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 135 3e-31
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 135 4e-31
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 135 5e-31
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 135 5e-31
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 135 5e-31
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 134 6e-31
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 134 6e-31
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 134 6e-31
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 134 6e-31
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 134 8e-31
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 134 8e-31
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 134 8e-31
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 134 8e-31
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 134 1e-30
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 133 1e-30
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 133 1e-30
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 133 2e-30
7302860 [T] KOG0696 Serine/threonine protein kinase 133 2e-30
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 133 2e-30
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 132 2e-30
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 132 2e-30
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 132 3e-30
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 132 3e-30
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 132 4e-30
CE21239 [T] KOG0583 Serine/threonine protein kinase 132 4e-30
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 131 5e-30
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 131 7e-30
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 131 7e-30
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 131 7e-30
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 131 7e-30
CE18366 [T] KOG0583 Serine/threonine protein kinase 130 9e-30
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 130 9e-30
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 130 9e-30
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 130 1e-29
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 130 1e-29
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 130 1e-29
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 130 1e-29
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 130 1e-29
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 130 1e-29
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 130 1e-29
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 130 1e-29
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 130 1e-29
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 130 1e-29
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 130 1e-29
7295638 [T] KOG0603 Ribosomal protein S6 kinase 130 1e-29
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 129 2e-29
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 129 2e-29
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 129 2e-29
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 129 3e-29
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 129 3e-29
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 129 3e-29
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 129 3e-29
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 129 3e-29
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 129 3e-29
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 129 3e-29
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 128 4e-29
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 128 4e-29
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 128 4e-29
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 128 4e-29
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 128 6e-29
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 128 6e-29
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 127 7e-29
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 127 7e-29
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 127 7e-29
Hs13649368 [T] KOG0583 Serine/threonine protein kinase 127 7e-29
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 127 1e-28
Hs5803125 [T] KOG0583 Serine/threonine protein kinase 127 1e-28
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 127 1e-28
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 127 1e-28
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 127 1e-28
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 127 1e-28
7301734 [T] KOG0694 Serine/threonine protein kinase 127 1e-28
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 127 1e-28
CE02586 [T] KOG0696 Serine/threonine protein kinase 127 1e-28
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 127 1e-28
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 127 1e-28
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 126 2e-28
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 126 2e-28
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 126 2e-28
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 126 2e-28
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 126 2e-28
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 126 2e-28
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 126 2e-28
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 126 2e-28
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 126 2e-28
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 126 2e-28
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 126 2e-28
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 125 3e-28
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 125 3e-28
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 125 3e-28
Hs4505811 [T] KOG0583 Serine/threonine protein kinase 125 3e-28
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 125 3e-28
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 125 3e-28
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 125 3e-28
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 125 3e-28
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 125 4e-28
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 125 4e-28
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 125 4e-28
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 125 4e-28
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 125 4e-28
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 125 4e-28
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 125 4e-28
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 125 5e-28
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 124 6e-28
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 124 6e-28
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 124 6e-28
7290147 [T] KOG0583 Serine/threonine protein kinase 124 6e-28
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 124 8e-28
7303111 [T] KOG0695 Serine/threonine protein kinase 124 8e-28
At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 123 1e-27
7302861 [T] KOG0696 Serine/threonine protein kinase 123 1e-27
Hs21237768 [T] KOG0604 MAP kinase-activated protein kinase 2 123 2e-27
Hs21237765 [T] KOG0604 MAP kinase-activated protein kinase 2 123 2e-27
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 123 2e-27
HsM4506035 [T] KOG0604 MAP kinase-activated protein kinase 2 122 2e-27
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 122 2e-27
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 122 2e-27
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 122 3e-27
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 122 4e-27
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 122 4e-27
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 122 4e-27
CE15235 [R] KOG0589 Serine/threonine protein kinase 122 4e-27
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 122 4e-27
YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 121 5e-27
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 121 5e-27
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 121 5e-27
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 121 5e-27
7294770 [T] KOG0603 Ribosomal protein S6 kinase 121 5e-27
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 121 7e-27
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 121 7e-27
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 121 7e-27
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 121 7e-27
7291707 [T] KOG1152 Signal transduction serine/threonine kinase ... 121 7e-27
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 120 9e-27
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 120 9e-27
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 120 9e-27
CE15612 [T] KOG0690 Serine/threonine protein kinase 120 9e-27
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 120 9e-27
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 120 1e-26
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 120 1e-26
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 120 1e-26
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 120 2e-26
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 120 2e-26
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 120 2e-26
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 119 2e-26
7291710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 119 2e-26
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 119 2e-26
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 119 3e-26
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 119 3e-26
Hs22064373 [D] KOG0588 Serine/threonine protein kinase 119 3e-26
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 119 3e-26
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 118 5e-26
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 118 5e-26
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 118 6e-26
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 118 6e-26
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 118 6e-26
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 118 6e-26
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 118 6e-26
7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 118 6e-26
At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protei... 118 6e-26
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 118 6e-26
YHR102w [T] KOG0201 Serine/threonine protein kinase 117 8e-26
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 117 8e-26
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 117 8e-26
CE05274 [T] KOG0690 Serine/threonine protein kinase 117 8e-26
CE03467 [T] KOG0604 MAP kinase-activated protein kinase 2 117 8e-26
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 117 1e-25
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 117 1e-25
At4g08480 [T] KOG0198 MEKK and related serine/threonine protein ... 117 1e-25
7296166 [T] KOG0614 cGMP-dependent protein kinase 117 1e-25
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 117 1e-25
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 117 1e-25
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 116 2e-25
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 116 2e-25
At4g08470 [T] KOG0198 MEKK and related serine/threonine protein ... 116 2e-25
YCR008w [D] KOG0590 Checkpoint kinase and related serine/threoni... 116 2e-25
Hs16950619 [Z] KOG0613 Projectin/twitchin and related proteins 116 2e-25
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 116 2e-25
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 115 3e-25
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 115 3e-25
Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 115 3e-25
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 115 4e-25
CE29092 [T] KOG0694 Serine/threonine protein kinase 115 5e-25
CE28993 [G] KOG0599 Phosphorylase kinase gamma subunit 115 5e-25
At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase 115 5e-25
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 114 7e-25
7297776 [D] KOG0580 Serine/threonine protein kinase 114 7e-25
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 114 9e-25
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 114 9e-25
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 114 1e-24
CE17354 [T] KOG0694 Serine/threonine protein kinase 114 1e-24
CE17353 [T] KOG0694 Serine/threonine protein kinase 114 1e-24
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 114 1e-24
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 113 1e-24
Hs16950615 [Z] KOG0613 Projectin/twitchin and related proteins 113 1e-24
CE27899 [D] KOG0590 Checkpoint kinase and related serine/threoni... 113 1e-24
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 113 1e-24
SPBC337.04 [R] KOG0586 Serine/threonine protein kinase 113 2e-24
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 113 2e-24
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 113 2e-24
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 113 2e-24
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 113 2e-24
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 112 2e-24
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 112 2e-24
Hs18596354 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 112 2e-24
ECU03g0620 [D] KOG0590 Checkpoint kinase and related serine/thre... 112 2e-24
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 112 2e-24
At5g58950 [T] KOG0192 Tyrosine kinase specific for activated (GT... 112 2e-24
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 112 2e-24
7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 112 2e-24
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 112 3e-24
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 112 3e-24
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 112 3e-24
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 112 4e-24
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 112 4e-24
YLR113w [T] KOG0660 Mitogen-activated protein kinase 111 6e-24
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 111 6e-24
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 111 6e-24
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 111 6e-24
CE27410 [T] KOG0583 Serine/threonine protein kinase 111 6e-24
7301004 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 111 6e-24
7291742_1 [T] KOG0612 Rho-associated coiled-coil containing prot... 111 7e-24
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 110 9e-24
SPAC29A4.16 [D] KOG0590 Checkpoint kinase and related serine/thr... 110 9e-24
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 110 9e-24
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 110 9e-24
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 110 9e-24
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 110 1e-23
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 110 1e-23
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 110 1e-23
YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 110 2e-23
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 110 2e-23
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 110 2e-23
At3g20860 [R] KOG0589 Serine/threonine protein kinase 110 2e-23
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 109 2e-23
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 109 2e-23
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 109 2e-23
Hs16950617 [Z] KOG0613 Projectin/twitchin and related proteins 109 2e-23
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 109 2e-23
Hs5902140_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 109 2e-23
7299507 [T] KOG0607 MAP kinase-interacting kinase and related se... 109 3e-23
YKL116c [R] KOG0586 Serine/threonine protein kinase 108 4e-23
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 108 4e-23
At3g46930 [T] KOG0192 Tyrosine kinase specific for activated (GT... 108 4e-23
Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases 108 5e-23
CE20717 [T] KOG0583 Serine/threonine protein kinase 108 5e-23
7303860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 108 5e-23
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 108 5e-23
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 108 6e-23
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 108 6e-23
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 108 6e-23
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 108 6e-23
ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase 108 6e-23
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 107 8e-23
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 107 8e-23
At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 107 8e-23
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 107 1e-22
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 986 bits (2549), Expect = 0.0
Identities = 579/1161 (49%), Positives = 743/1161 (63%), Gaps = 106/1161 (9%)
Query: 1 MNGNGITTLKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNA---QG 57
+NGN I +K +TIGPWKLG TLG+GSTGKV +A N + GQ+AAVK+ISK++FN G
Sbjct: 3 INGNSIPAIKDNTIGPWKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSG 62
Query: 58 STMIGGNDPDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLL 117
++++G PD LPYGIEREIIIMKLLNHPNVLRLYDVWET+ DLY+VLEY EKGELFNLL
Sbjct: 63 TSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLL 122
Query: 118 VERGPLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALES 177
VERGPLPE+EA+RFFRQIIIG+SYCHALGIVHRDLKPENLLLDHK+N+K+ADFGMAALE+
Sbjct: 123 VERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALET 182
Query: 178 KDKLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLL 237
+ KLLETSCGSPHYAAPEIVSG+PY GF SDVWSCGVIL+ALLTGRLPFDEEDGNIR LL
Sbjct: 183 EGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLL 242
Query: 238 LKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIR 297
LKVQ G+FEMP DDEIS EAQDLI +ILTVDPE+RIKTR+ILKHPLL+KYPSI+DSKSIR
Sbjct: 243 LKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQKYPSIRDSKSIR 302
Query: 298 NLPREDTYLNPLSLEGGNQCVDETILQNLVVLWHGRNKEDIITKLMEPGANLEKTFYALL 357
LPREDTYL PLS N +D TILQNLV+LWHGR+ E I KL EPGAN EKT YALL
Sbjct: 303 GLPREDTYLTPLS--ESNSSIDATILQNLVILWHGRDPEGIKEKLREPGANAEKTLYALL 360
Query: 358 HRFKHDNYXXXXXXXXXXXXXSVSSNSLMYVGSLPSPNKSDSPVTTPKKKRTSIIVASSS 417
+RFK D S+SS S+ SP+K S ++ R S+I +SS
Sbjct: 361 YRFKCDTQKELIKQQQVKKRQSISSVSV-------SPSKKVSTTPQRRRNRESLISVTSS 413
Query: 418 HKRPVSMQKL--SSQHSSPVKNGSIGKRLSKTFPSNKRISQLVSNSSSPTPAA-HKRVSR 474
K+P+S K SS SS + KRLSK F S K++S +V N SSPTPA+ +KR S
Sbjct: 414 RKKPISFNKFTASSASSSNLTTPGSSKRLSKNFSSKKKLSTIV-NQSSPTPASRNKRASV 472
Query: 475 INDSAAPPVPKEMLR-------DYKRQSKRQSKRFSLLPNMKRGSITTKLIATYAKLSED 527
IN V K R ++S R KR SL+P+MKR S+TTKL++TYAKL+ED
Sbjct: 473 IN------VEKNQKRASIFSTTKKNKRSSRSIKRMSLIPSMKRESVTTKLMSTYAKLAED 526
Query: 528 SEWEYIEKETKRTSQDFATLMDQIFEHEKYEQIRKEKEELXXXXXXXXXXXXXXXXXXXX 587
+WEYIEKETKRTS +FATL+D+IFE+EKYEQIRKEKEEL
Sbjct: 527 DDWEYIEKETKRTSSNFATLIDEIFEYEKYEQIRKEKEEL-ERKVREAKAREELERRRRK 585
Query: 588 XXXXXXXXXXXXXXXXXXXXXXLQDQMEDEIAKLKAEYEAVQGSSDERNTANGRSVSAPI 647
L+ Q+E +I+ L+ E + +E+ N RS+SAP+
Sbjct: 586 QEEKERARKLLEKEDLKRKQEELKKQIEIDISDLEQE---LSKHKEEKLDGNIRSISAPM 642
Query: 648 ETDRTANKRDSTFGIKNDINELINTRNFSLQTRPVSRLDPGIIAAESRLSAN------LE 701
E N+ + ++ DI+ ++ RNFSLQTRPVSRLDPGI+ + + E
Sbjct: 643 E-----NEEKNINHLEVDIDNILRRRNFSLQTRPVSRLDPGIMFSSPTEEVSPVEPKRTE 697
Query: 702 DDQASKEKTILETIRRSKFLGSQFNLNVELEKAQKD---LVSKERQEQLRKYSEQTAKYE 758
+++ + EK ILETIRRSKFLGS FN++ EL+ ++ + +++ +R + R S+ YE
Sbjct: 698 NERLTTEKKILETIRRSKFLGSSFNIDKELKLSKMEYPSIIAPQRLSEERVVSDSNDGYE 757
Query: 759 VQKLPKNAKAVATLRDDEVEP--------RKLSEVKVPQFTRRSKHFSSSNKRFSVLSLY 810
LPK+ V+ L+D RK+SE++VPQFTR+S+HFS SNKR SVLS+Y
Sbjct: 758 SLILPKDGNGVSQLKDSTATTAPVSDGRLRKISEIRVPQFTRKSRHFSESNKRLSVLSMY 817
Query: 811 STKTSFTNLVDHLKNDNYLEPLPGQPEYSSSKVAQEPEFMFETVEELDE-------NSKL 863
STK SFTNLVD LKN N + + A + EF+FETV E E + +L
Sbjct: 818 STKESFTNLVDILKNGNLDVNNQQSQRIPTPRSADDSEFLFETVNEEAEYTGNSSNDERL 877
Query: 864 FEVPET-----EEGKLASAARKESTDARKQSTNDKDINLPSLPPLQVSHDVADENGALGL 918
++V ++ KL A R ++ KQ+ N ++LP LPPL +++ +N G
Sbjct: 878 YDVGDSTIKDKSALKLNFADRFNGSNEAKQTDN---LHLPILPPLNGDNELRKQNSQEGD 934
Query: 919 GIYQ----------PNDQTQKPHKTMLIDESIDENISSTSDVSRTEVV---KKPPLNDVV 965
+ + T+K + +E E D + E V +PPLN V
Sbjct: 935 QAHPKIKSMIPESGSSSHTEKEEENEEKEEKKPEQHKQEEDQEKREKVVDDMEPPLNKSV 994
Query: 966 RK----------NNNERKPLEEITPKVENKRKI---SFFRKFSQGSEKKLGPESFDSQLK 1012
+K ++ + L+E K + I SFFRKFS+ S+K + +L
Sbjct: 995 QKIREKNAGSQAKDHSKDHLKE--HKQDKNTAIGNGSFFRKFSKSSDKTM-------ELY 1045
Query: 1013 AGVSAPKMYKALDRLLNEWTNYGLKHVESSPNDFVISGKLTSDNILSLRSTGFKITVLPG 1072
A +SA +++ L++LL WT YGLK+++S PN+ ++GKL+SDNI SLRST F++ + P
Sbjct: 1046 AKISAKQLFNGLEKLLRGWTQYGLKNIKSHPNNLTLTGKLSSDNIFSLRSTLFEVNIYP- 1104
Query: 1073 EGNGSIIQFTKKSGSTKTFNR 1093
G S++QF K SGS K +
Sbjct: 1105 RGKMSVVQFKKVSGSFKAVKK 1125
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 752 bits (1942), Expect = 0.0
Identities = 472/1113 (42%), Positives = 641/1113 (57%), Gaps = 141/1113 (12%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYG 72
TIGPWKLG TLG GSTGKV +A +E G + AVK+ISKSIFN G+ ND VLPY
Sbjct: 17 TIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNH---SNDDSVLPYN 73
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
IEREI+IMKLL+HPNVL LYDVWET+ +LY++LEY EKGELFNLLV+ GPLPE EA+ F
Sbjct: 74 IEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCF 133
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
RQIIIGISYCHALGIVHRDLKPENLLLD +N+K+ADFGMAAL++ LLETSCGSPHYA
Sbjct: 134 RQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYA 193
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDE 252
APEIVSGLPY GF SDVWSCGVIL+ALLTGRLPFDEE+GN+R+LLLKVQ G+FEMP D E
Sbjct: 194 APEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTE 253
Query: 253 ISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPL--S 310
IS +AQDLI +IL VDP QRIK R+IL HPLL+KY +IKDSKSI++LPRE+TYL PL S
Sbjct: 254 ISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADS 313
Query: 311 LEGGNQCVDETILQNLVVLWHGRNKEDIITKLMEPGANLEKTFYALLHRFKHDNYXXXXX 370
+ +D++ILQNLVVLWHGR+ +DI++KL E G N EK YALL+RFK D
Sbjct: 314 NNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLD------- 366
Query: 371 XXXXXXXXSVSSNSLMYVGSLPSPNKS--DSPVTTPKKKRTSIIVASSSHKRPVSMQKLS 428
S+ NK + T K KR+S + +SSS +
Sbjct: 367 -------------------SVRGSNKKNRNKIKKTKKNKRSSTLSSSSS-----LLLNNR 402
Query: 429 SQHSSPVKNGSIGKRLSKTFPSNKRISQLVSNS----SSPTP-AAHKRVSRINDSAA--P 481
S S+P + S KR S+ F S+++ S + +S SSP P + KR++ IN ++A
Sbjct: 403 SIQSTPRRRTS--KRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQ 460
Query: 482 PVPKEMLRDYKRQS-KRQSKRFSLLPNMKRGSITTKLIATYAKLSEDSEWEYIEKETKRT 540
P + +KR S KR SKR S +PN KR S+T+K ++ + L +D +WEYIEK+ KRT
Sbjct: 461 ATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRT 520
Query: 541 SQDFATLMDQIFEHEKYEQIRKEKEELXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 600
S +FATL+D+IFE EK+E ++EK EL
Sbjct: 521 SSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKIN--------------- 565
Query: 601 XXXXXXXXXLQDQMEDEIAKLKAEYEAVQGSSDERNTANGRSVSAPIETDRTANKRDSTF 660
+D+ E++ E + + VS+P+ N S
Sbjct: 566 ----------EDEFGSEVSDGMKELKKIND-----------KVSSPL-----INYEFSQQ 599
Query: 661 GIKNDINELINTR-NFSLQTRPVSRLDPGIIAAESRLSANLEDDQA---SKEKTILETIR 716
+ DI+ L+ R S TRP+SRLDPG+ L NL++ A EK I+ETIR
Sbjct: 600 ELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIR 659
Query: 717 RSKFLGSQFNLNVELEKAQKDLVSKERQEQLRKYSEQTAKYEVQKLPKNAKAVATLRDDE 776
RSKFLGS N+ L + +L E + + +D
Sbjct: 660 RSKFLGSLLNVRGGLSPGKSELAPIEESPIV-------------------STTPLIYNDR 700
Query: 777 VEPRKLSEVKVPQFTRRSKHFSSSNKRFSVLSLYSTKTSFTNLVDHLKNDNYLEPLPGQP 836
+EPR++S+V+VP FTR+SKHF+++N R SVLSLY+ K S +L + L ++ LP Q
Sbjct: 701 MEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYA-KDSIKDLNEFLIKED--PDLPPQG 757
Query: 837 EYSSSKVAQEPEFMFETVEELDENSKLFEVPETEEGKLAS-----------AARKESTDA 885
+ +++PE + E++ D + ++ ++++G + + D
Sbjct: 758 STDNESRSEDPE-IAESI--TDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDM 814
Query: 886 RKQSTNDKDINLPSLPPLQV---SHDVADENGALGLGIYQPNDQTQKPHKTMLIDESIDE 942
+ ++ N I+ + P L V S A GLG+YQ + S+ E
Sbjct: 815 KDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGE 874
Query: 943 NISSTSDVSRTEVVKKPPLNDVVRKNNNERKPLEEITPKVENKRKIS--FFRKFSQGSEK 1000
NI ++ L+D K +N++K + + K+ + +KFS+G
Sbjct: 875 NIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKIL 934
Query: 1001 KLGPESFDSQLKAGVSAPKMYKALDRLLNEWTNYGLKHVESSPNDFVISGKLTSDNILSL 1060
+L ++ A + ++Y+ L +LL W YGLK++ + + +I+GKL +D+IL L
Sbjct: 935 EL-------EIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFL 987
Query: 1061 RSTGFKITVLPGEGNGSIIQFTKKSGSTKTFNR 1093
RST F+I VLP S+I+F KK+GSTKT +
Sbjct: 988 RSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTK 1020
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 378 bits (970), Expect = e-104
Identities = 200/390 (51%), Positives = 273/390 (69%), Gaps = 45/390 (11%)
Query: 12 DTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISK-----------SIFNAQGSTM 60
DT+GPWKLG TLG GS+G+V +A N GQ AA+KI+ K ++ N+ S+M
Sbjct: 76 DTVGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSM 135
Query: 61 IGGN--DPDVL-----------PYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEY 107
+ N P + PYGIEREI+IMKL++H NV+ L++VWE +LY+VLEY
Sbjct: 136 VTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEY 195
Query: 108 VEKGELFNLLVERGPLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHK-FNVK 166
V+ GELF+ LV +G LPE EA+ +F+QI+ G+SYCH+ I HRDLKPENLLLD K +K
Sbjct: 196 VDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIK 255
Query: 167 LADFGMAALESKDKLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF 226
+ADFGMAALE +KLL+TSCGSPHYA+PEIV G PYHG SDVWSCG++L+ALLTG LPF
Sbjct: 256 IADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPF 315
Query: 227 DEEDGNIRNLLLKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
+ D NI+ LLLKVQSGK++MP + +SSEA+DLI++IL +DPE+RI T+EILKHPL++K
Sbjct: 316 N--DDNIKKLLLKVQSGKYQMPSN--LSSEARDLISKILVIDPEKRITTQEILKHPLIKK 371
Query: 287 YPSIKDSKSIRNLPREDT----------YLNPLS-----LEGGNQCVDETILQNLVVLWH 331
Y + +K +R + +++ LN +S L + +DE+IL++L +LWH
Sbjct: 372 YDDLPVNKVLRKMRKDNMARGKSNSDLHLLNNVSPSIVTLHSKGE-IDESILRSLQILWH 430
Query: 332 GRNKEDIITKLMEPGANLEKTFYALLHRFK 361
G ++E I KL++ + EK FY+LL ++K
Sbjct: 431 GVSRELITAKLLQKPMSEEKLFYSLLLQYK 460
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 274 bits (701), Expect = 5e-73
Identities = 150/343 (43%), Positives = 210/343 (60%), Gaps = 21/343 (6%)
Query: 15 GPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIE 74
GP+KL TLG G TG V + G++ A+KI++K + + + +E
Sbjct: 45 GPYKLEKTLGKGQTGLVKTGTHCITGRKVAIKIVNKEKLS------------ESVLQKVE 92
Query: 75 REIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQ 134
REI IMKL+ HP+VL LYDV+E K LY++LE+V GELF+ LV +G L EA +FFRQ
Sbjct: 93 REIAIMKLIEHPHVLHLYDVYENKKYLYLLLEHVSGGELFDYLVRKGRLMSKEARKFFRQ 152
Query: 135 IIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAP 194
II + +CHA I HRDLKPENLLLD + N+K+ADFGMA+L+ + +LETSCGSPHYA P
Sbjct: 153 IISALDFCHAHNICHRDLKPENLLLDERNNIKVADFGMASLQVEGSMLETSCGSPHYACP 212
Query: 195 EIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEIS 254
E++ G Y G ++DVWSCGVILYALL G LPFD D N+RNLL KV+ G F +P +
Sbjct: 213 EVIRGEKYDGRKADVWSCGVILYALLVGALPFD--DDNLRNLLEKVKRGVFHIP--HFVP 268
Query: 255 SEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPLSLEGG 314
++ Q L+ ++ VDP +R ++ KHP + + T++ P G
Sbjct: 269 ADVQSLLRAMIEVDPGKRYSLADVFKHPWVSGTTKADPELELPMSQVVQTHVIP-----G 323
Query: 315 NQCVDETILQNLVVLWHGRNKEDIITKLMEPGANLEKTFYALL 357
+D +L+++ L ++K+ +I +L+ P N EK Y LL
Sbjct: 324 EDSIDPDVLRHMNCLGCFKDKQKLINELLSPKHNTEKMVYFLL 366
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 266 bits (679), Expect = 2e-70
Identities = 149/354 (42%), Positives = 213/354 (60%), Gaps = 21/354 (5%)
Query: 4 NGITTLKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGG 63
N +T +GP++L TLG G TG V + + G++ A+KII++ +
Sbjct: 5 NNVTAENCQFVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLS--------- 55
Query: 64 NDPDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPL 123
+ + +EREI IMKL++HP+VL L DV+E K LY++LE+V GELF+ LV++G L
Sbjct: 56 ---ESVLMKVEREIAIMKLIDHPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRL 112
Query: 124 PENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLE 183
EA +FFRQII + +CH+ I HRDLKPENLLLD K N+K+ADFGMA+L+ +LE
Sbjct: 113 TPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIKIADFGMASLQPAGSMLE 172
Query: 184 TSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSG 243
TSCGSPHYA PE++ G Y G ++DVWSCGVILYALL G LPFD D N+R LL KV+ G
Sbjct: 173 TSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFD--DDNLRQLLEKVKRG 230
Query: 244 KFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPRED 303
F +P + + Q L+ ++ V+P++R+ EI +HP + + + +
Sbjct: 231 VFHIP--HFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAGGKGELELELPMMEVVQ 288
Query: 304 TYLNPLSLEGGNQCVDETILQNLVVLWHGRNKEDIITKLMEPGANLEKTFYALL 357
T++ P + VD +L + L + KE +I +L+ N EK Y LL
Sbjct: 289 THVIPTA-----TAVDPDVLNAICSLGCFKEKEKLIQELLSSSHNTEKVIYFLL 337
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 265 bits (678), Expect = 2e-70
Identities = 149/346 (43%), Positives = 212/346 (61%), Gaps = 24/346 (6%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+GP++L TLG G TG V + + GQ+ A+KI+++ + + + +
Sbjct: 48 VGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLS------------ESVLMKV 95
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
EREI I+KL+ HP+VL+L+DV+E K LY+VLE+V GELF+ LV++G L EA +FFR
Sbjct: 96 EREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFR 155
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QI+ + +CH+ I HRDLKPENLLLD K N+++ADFGMA+L+ D LLETSCGSPHYA
Sbjct: 156 QIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYAC 215
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE++ G Y G +D+WSCGVIL+ALL G LPFD D N+R LL KV+ G F MP I
Sbjct: 216 PEVIKGEKYDGRRADMWSCGVILFALLVGALPFD--DDNLRQLLEKVKRGVFHMP--HFI 271
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHP--LLRKYPSIKDSKSIRNLPREDTYLNPLSL 311
+ Q L+ ++ V+PE+R+ +I KHP L K+ + + P + L
Sbjct: 272 PPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKH---EPDPCLEPAPGRRVAMRSLPS 328
Query: 312 EGGNQCVDETILQNLVVLWHGRNKEDIITKLMEPGANLEKTFYALL 357
G +D +L+++ L R++E + +L N EK Y LL
Sbjct: 329 NGE---LDPDVLESMASLGCFRDRERLHRELRSEEENQEKMIYYLL 371
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 265 bits (676), Expect = 4e-70
Identities = 159/367 (43%), Positives = 228/367 (61%), Gaps = 37/367 (10%)
Query: 1 MNGNGITTLKG-DTIGP-WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISK-SIFNAQG 57
M+G+G + G ++I P +KLG TLG+GS G+V +A + G + A+KI+++ I N +
Sbjct: 1 MDGSGTGSRSGVESILPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNME- 59
Query: 58 STMIGGNDPDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLL 117
+ + REI I++L HP+++RLY+V ET D+Y+V+EYV GELF+ +
Sbjct: 60 -----------MEEKVRREIKILRLFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYI 108
Query: 118 VERGPLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALES 177
VE+G L E+EA FF+QII G+ YCH +VHRDLKPENLLLD K NVK+ADFG++ +
Sbjct: 109 VEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSKCNVKIADFGLSNIMR 168
Query: 178 KDKLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLL 237
L+TSCGSP+YAAPE++SG Y G E DVWSCGVILYALL G LPFD+E NI NL
Sbjct: 169 DGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE--NIPNLF 226
Query: 238 LKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIR 297
K++ G + +P +S A+DLI R+L VDP +R+ EI +HP + +
Sbjct: 227 KKIKGGIYTLP--SHLSPGARDLIPRMLVVDPMKRVTIPEIRQHPWFQAH---------- 274
Query: 298 NLPREDTYLNPLSLEGGNQCVDETILQNLVVLWHGRNK--EDIITKLMEPGANLEKTFYA 355
LPR P +++ + +DE ILQ ++ + RN E + + G T+Y
Sbjct: 275 -LPRYLAVPPPDTVQQAKK-IDEEILQEVINMGFDRNHLIESLRNRTQNDGT---VTYYL 329
Query: 356 LL-HRFK 361
+L +RF+
Sbjct: 330 ILDNRFR 336
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 261 bits (667), Expect = 4e-69
Identities = 154/348 (44%), Positives = 220/348 (62%), Gaps = 33/348 (9%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISK-SIFNAQGSTMIGGNDPDVLPYGIER 75
+KLG TLG+GS GKV +A + G + A+KI+++ I N + + + R
Sbjct: 20 YKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNME------------MEEKVRR 67
Query: 76 EIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
EI I++L HP+++R Y+V ET+ D+Y+V+EYV+ GELF+ +VE+G L E+EA FF+QI
Sbjct: 68 EIKILRLFMHPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQI 127
Query: 136 IIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPE 195
I G+ YCH +VHRDLKPENLLLD + N+K+ADFG++ + L+TSCGSP+YAAPE
Sbjct: 128 ISGVEYCHRNMVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDGHFLKTSCGSPNYAAPE 187
Query: 196 IVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISS 255
++SG Y G E DVWSCGVILYALL G LPFD+E NI NL K++ G + +P +SS
Sbjct: 188 VISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE--NIPNLFKKIKGGIYTLP--SHLSS 243
Query: 256 EAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPLSLEGGN 315
EA+DLI R+L VDP +RI EI +H + + LPR P ++E
Sbjct: 244 EARDLIPRMLIVDPVKRITIPEIRQHRWFQTH-----------LPRYLAVSPPDTVEQAK 292
Query: 316 QCVDETILQNLVVLWHGRNKEDIITKLMEPGAN-LEKTFYALL-HRFK 361
+ ++E I+Q +V + RN+ ++ L N T+Y LL +RF+
Sbjct: 293 K-INEEIVQEVVNMGFDRNQ--VLESLRNRTQNDATVTYYLLLDNRFR 337
>SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase
Length = 775
Score = 253 bits (647), Expect = 9e-67
Identities = 178/521 (34%), Positives = 263/521 (50%), Gaps = 52/521 (9%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVK-IISKSIFNAQGSTMIGGNDPDVLPYG 72
+GPW+LG +LG G +A + GQ A VK I+ S + I G
Sbjct: 7 VGPWELGLSLGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEG--------- 57
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
E+++++L+ HPNVL+L DV + L++V+EY+ GELF+ ++ +G E + +F
Sbjct: 58 ---ELVLLRLIEHPNVLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFL 114
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
QI+ G+ YCH L I HRDLKPENL LD ++K+ +FGMA+++ KLL+TSCGSPHYA
Sbjct: 115 WQILCGLEYCHKLHICHRDLKPENLYLDAHGSIKIGEFGMASIQQPGKLLQTSCGSPHYA 174
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDE 252
+PEI+ G Y G SD+WSCG+I +ALLTG+LPFD D NIR+LLLKV G+FEMP +
Sbjct: 175 SPEIIMGRSYDGCASDIWSCGIIFFALLTGKLPFD--DDNIRSLLLKVCQGQFEMPSN-- 230
Query: 253 ISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPLSLE 312
IS +AQ L+ R+L VD RI +I +HP L + S I + P
Sbjct: 231 ISPQAQHLLYRMLDVDSSTRITMEQIREHPFLSCFVHPNISIPIISAP------------ 278
Query: 313 GGNQCVDETILQNLVVLWH-GRNKEDIITKLMEPGANLEKTFYALLHRFKHDNYXXX--- 368
Q +D I+Q+L +++ + + KL +EKT Y LL R H
Sbjct: 279 --IQPIDPLIVQHLSLVFRCSDDPMPLYEKLASQSPLVEKTLYTLLSRHLHPPSSAAVDR 336
Query: 369 XXXXXXXXXXSVSSNSLMYVGSLPSPNKSDSPVTTPKKKRTSIIVASSSHKRPVSMQKLS 428
+ +SN G + + + P I A+ S RP + +
Sbjct: 337 NRAVVDDLLGTAASN-----GQQMDEEEIEQAINIPTLAPYPISYAAESVPRPATS---A 388
Query: 429 SQHSSPV-KNGSIGKRLSKTFPSNKRISQLVSNSSSPTPAAHKRVSRINDSAAPPVPKEM 487
S +PV +G+ + T P + I Q + +SS P K V+ A P M
Sbjct: 389 SPFLTPVTTSGTFNYSFNATNPQS--ILQRPATTSSAVPQLPKSVT---PGLAYPHDSSM 443
Query: 488 L-RDYKRQSKRQSKRFSLLPNMKRGSITTKLIATYAKLSED 527
L +Y+ S + F++ N ++ + AT +S D
Sbjct: 444 LSSNYRPPSALSPRNFNVSINDPEVQLSRR--ATSLDMSND 482
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 251 bits (641), Expect = 4e-66
Identities = 142/329 (43%), Positives = 205/329 (62%), Gaps = 29/329 (8%)
Query: 7 TTLKGDTIGP-WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGND 65
TT K +I P +++G TLG GS KV +A + G + A+KI+++S G
Sbjct: 8 TTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMG-------- 59
Query: 66 PDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPE 125
+ ++REI I++ L HP+++R Y+V ET D+Y+V+EYV+ GELF+ +VE+G L E
Sbjct: 60 ---IEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQE 116
Query: 126 NEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETS 185
+EA F+QII G+ YCH IVHRDLKPEN+LLD + N+K+ DFG++ + L+TS
Sbjct: 117 DEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTS 176
Query: 186 CGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKF 245
CGSP+YAAPE++SG PY G + D+WSCGVILYALL G LPFD+E NI N+ K++ G +
Sbjct: 177 CGSPNYAAPEVISGKPY-GPDVDIWSCGVILYALLCGTLPFDDE--NIPNVFEKIKRGMY 233
Query: 246 EMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTY 305
+P + +S A+DLI R+L VDP RI EI +HP + + S
Sbjct: 234 TLP--NHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLS------------ 279
Query: 306 LNPLSLEGGNQCVDETILQNLVVLWHGRN 334
+ PL + ++E I+QN+V + RN
Sbjct: 280 IPPLDTIDQAKKIEEEIIQNVVNIGFDRN 308
>SPAC644.06c [D] KOG0588 Serine/threonine protein kinase
Length = 593
Score = 243 bits (619), Expect = 2e-63
Identities = 152/433 (35%), Positives = 227/433 (52%), Gaps = 37/433 (8%)
Query: 12 DTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPY 71
+TIG W+LG TLG GST V +A + G AA+KII +
Sbjct: 7 NTIGVWRLGKTLGTGSTSCVRLAKHAKTGDLAAIKIIP------------------IRYA 48
Query: 72 GIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRF 131
I EI++M+LL HPN+LRLYDVW + +Y+ LEYV GELF+ + + GPL E EA +
Sbjct: 49 SIGMEILMMRLLRHPNILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHY 108
Query: 132 FRQIIIGISYCHALGIVHRDLKPENLLLD-HKFNVKLADFGMAALESKDKLLETSCGSPH 190
QI+ +++CH HRDLK EN+L+ ++ +K+ADFGMA +E D LE CGS H
Sbjct: 109 LSQILDAVAHCHRFRFRHRDLKLENILIKVNEQQIKIADFGMATVEPNDSCLENYCGSLH 168
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
Y APEIVS PY G +DVWSCGVILY+LL+ +LPF ++ ++ + K++ G +++P
Sbjct: 169 YLAPEIVSHKPYRGAPADVWSCGVILYSLLSNKLPFGGQNTDV--IYNKIRHGAYDLP-- 224
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPLS 310
ISS AQDL+ R+L V+P RI E+ HP L S+ S P + LS
Sbjct: 225 SSISSAAQDLLHRMLDVNPSTRITIPEVFSHPFLMGCTSLSSMDS--TTPPTPS----LS 278
Query: 311 LEGGNQCVDETILQNLVVLWHGRNKEDIITKLMEPGANLEKTFYALLHRFKHDNY---XX 367
++ +D ++ + VLW + + ++ +L + N EK Y +L D+
Sbjct: 279 IDE----IDPLVVDCMCVLWKKSSSKKVVRRLQQRDDNDEKYVYKVLSEILRDDMLKKQR 334
Query: 368 XXXXXXXXXXXSVSSNSLMYVGSLPSPNKSDSPVTTPKKKRTSIIVASSSH-KRPVSMQK 426
+ N+L S+ + + S V+T +K ++ + P+S
Sbjct: 335 FDENKYLSLYDLIHDNNLFTKASISTTSLVKSNVSTNSRKSSNFEDELARRVSSPLSALN 394
Query: 427 LSSQHSSPVKNGS 439
SQ P++ S
Sbjct: 395 QMSQSPIPIRVSS 407
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 242 bits (617), Expect = 3e-63
Identities = 150/345 (43%), Positives = 199/345 (57%), Gaps = 32/345 (9%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
IGP+ + TLG GS GKV +A + Q+ A+K IS+ + M +
Sbjct: 31 IGPYIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHM-----------RV 79
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
EREI +KLL HP++++LYDV T D+ MV+EY GELF+ +VE+ + E+E RFF+
Sbjct: 80 EREISYLKLLRHPHIIKLYDVITTPTDIVMVIEYAG-GELFDYIVEKKRMTEDEGRRFFQ 138
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QII I YCH IVHRDLKPENLLLD NVK+ADFG++ + + L+TSCGSP+YAA
Sbjct: 139 QIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNIMTDGNFLKTSCGSPNYAA 198
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+++G Y G E DVWSCG++LY +L GRLPFD+E I NL KV S + MP D +
Sbjct: 199 PEVINGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDE--FIPNLFKKVNSCVYVMP--DFL 254
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPLSLEG 313
S AQ LI R++ DP QRI +EI + P NLP YL P+
Sbjct: 255 SPGAQSLIRRMIVADPMQRITIQEIRRDPWFNV-----------NLP---DYLRPMEEVQ 300
Query: 314 GNQCVDETILQNLVVLWHGRNKEDIITKLMEPGANLEKTFYALLH 358
G+ D I+ L G +++ I+ L N K Y LLH
Sbjct: 301 GSY-ADSRIVSKLGEAM-GFSEDYIVEALRSDENNEVKEAYNLLH 343
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 241 bits (614), Expect = 6e-63
Identities = 133/306 (43%), Positives = 192/306 (62%), Gaps = 29/306 (9%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
IG + LG+TLG G+ GKV + ++ + AVKI+++ + ++G I
Sbjct: 25 IGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQ--KIKSLDVVGK---------I 73
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
REI +KL HP++++LY V T D++M++EYV GELF+ +V+ G L E++A RFF+
Sbjct: 74 RREIQNLKLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQ 133
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QII G+ YCH IVHRDLKPENLLLDH +VK+ADFG++ + + L TSCGSP+YAA
Sbjct: 134 QIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAA 193
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE++SG Y G E D+WSCGVILYALL G LPFD+E ++ L K++SG F +P + +
Sbjct: 194 PEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDE--HVPTLFRKIKSGIFPIP--EYL 249
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPLSLEG 313
+ + +L+ ++L VDP +R EI KH +K +LP YL P S+E
Sbjct: 250 NKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQK-----------DLP---AYLFPSSIEQ 295
Query: 314 GNQCVD 319
+ +D
Sbjct: 296 DSNVID 301
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 233 bits (595), Expect = 1e-60
Identities = 142/335 (42%), Positives = 199/335 (59%), Gaps = 19/335 (5%)
Query: 11 GDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLP 70
G IG +++ TLG GS GKV +AY+ T GQ+ A+KII+K + S M G
Sbjct: 49 GAHIGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAK--SDMQGR------- 99
Query: 71 YGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVR 130
IEREI ++LL HP++++LYDV ++ ++ MV+EY ELF+ +V+R + E EA R
Sbjct: 100 --IEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGN-ELFDYIVQRDKMSEQEARR 156
Query: 131 FFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPH 190
FF+QII + YCH IVHRDLKPENLLLD NVK+ADFG++ + + L+TSCGSP+
Sbjct: 157 FFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPN 216
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
YAAPE++SG Y G E DVWSCGVILY +L RLPFD+E +I L + +G + +P
Sbjct: 217 YAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDE--SIPVLFKNISNGVYTLP-- 272
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLR-KYPSIKDSKSIRNLPREDTYLNPL 309
+S A LI R+L V+P RI EI++ + P ++ P E+ N
Sbjct: 273 KFLSPGAAGLIKRMLIVNPLNRISIHEIMQDDWFKVDLPEYLLPPDLKPHPEEENENNDS 332
Query: 310 SLEGGNQCVDE--TILQNLVVLWHGRNKEDIITKL 342
+G + DE L N++ G K++I L
Sbjct: 333 KKDGSSPDNDEIDDNLVNILSSTMGYEKDEIYESL 367
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 231 bits (588), Expect = 6e-60
Identities = 127/288 (44%), Positives = 182/288 (63%), Gaps = 21/288 (7%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
IG + L TLGVG+ GKV + +ET + AVKI+++ + ++G I
Sbjct: 22 IGHYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQ--KIKSLDVVGK---------I 70
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
REI + L HP+++RLY V T D++M++E+V GELF+ +V+ G L EA RFF+
Sbjct: 71 RREIQNLSLFRHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQ 130
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QII G+ YCH +VHRDLKPENLLLD + NVK+ADFG++ + + L TSCGSP+YAA
Sbjct: 131 QIISGVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGDFLRTSCGSPNYAA 190
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE++SG Y G E DVWSCGVILYALL G LPFD+E ++ +L K++SG F P D +
Sbjct: 191 PEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE--HVPSLFRKIKSGVFPTP--DFL 246
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRK------YPSIKDSKS 295
+L+ +L VDP +R ++++ H +K +P I +S++
Sbjct: 247 ERPIVNLLHHMLCVDPMKRATIKDVIAHEWFQKDLPNYLFPPINESEA 294
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 231 bits (588), Expect = 6e-60
Identities = 127/288 (44%), Positives = 182/288 (63%), Gaps = 21/288 (7%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
IG + L TLGVG+ GKV + +ET + AVKI+++ + ++G I
Sbjct: 22 IGHYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQ--KIKSLDVVGK---------I 70
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
REI + L HP+++RLY V T D++M++E+V GELF+ +V+ G L EA RFF+
Sbjct: 71 RREIQNLSLFRHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQ 130
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QII G+ YCH +VHRDLKPENLLLD + NVK+ADFG++ + + L TSCGSP+YAA
Sbjct: 131 QIISGVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGDFLRTSCGSPNYAA 190
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE++SG Y G E DVWSCGVILYALL G LPFD+E ++ +L K++SG F P D +
Sbjct: 191 PEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE--HVPSLFRKIKSGVFPTP--DFL 246
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRK------YPSIKDSKS 295
+L+ +L VDP +R ++++ H +K +P I +S++
Sbjct: 247 ERPIVNLLHHMLCVDPMKRATIKDVIAHEWFQKDLPNYLFPPINESEA 294
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 222 bits (566), Expect = 2e-57
Identities = 137/417 (32%), Positives = 221/417 (52%), Gaps = 34/417 (8%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
IG + LG TLGVG+ GKV + ++ G + AVKI+++ + ++G I
Sbjct: 13 IGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQ--KIRSLDVVGK---------I 61
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
+REI +KL HP++++LY V T D +MV+EYV GELF+ + + G + E EA R F+
Sbjct: 62 KREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQ 121
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QI+ + YCH +VHRDLKPEN+LLD N K+ADFG++ + S + L TSCGSP+Y A
Sbjct: 122 QILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYTA 181
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE++SG Y G E D+WSCGVILYALL G LPFD+E ++ L K++ G F +P + +
Sbjct: 182 PEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDE--HVPTLFKKIRGGVFYIP--EYL 237
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPLSLEG 313
+ L+ +L VDP +R ++I +H + + LP +YL P
Sbjct: 238 NRSVATLLMHMLQVDPLKRATIKDIREHEWFK-----------QGLP---SYLFPEDPSY 283
Query: 314 GNQCVDETILQNLVVLWHGRNKEDIITKLM--EPGANLEKTFYALLHRFKHDNYXXXXXX 371
+D+ ++ + + E ++ L +P L ++ ++ + N
Sbjct: 284 DANVIDDEAVKEVCEKFECTESE-VMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYL 342
Query: 372 XXXXXXXSVSSNSLMYV--GSLPSPNKSDSPVTTPKKKRTSIIVASSSHKRPVSMQK 426
S +S M++ G P P + + K R + +++ + ++++K
Sbjct: 343 ASSPPSGSFMDDSAMHIPPGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKK 399
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 221 bits (562), Expect = 6e-57
Identities = 121/268 (45%), Positives = 172/268 (64%), Gaps = 16/268 (5%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G ++LG T+G G+ KV A N G+ A+KI+ +S T+I D I
Sbjct: 6 VGKYELGRTIGEGTFAKVKFAQNTETGESVAMKIVDRS-------TIIKRKMVDQ----I 54
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
+REI IMKL+ HP V+RLY+V + +Y++LEY+ GELF+ +V G L E+EA ++F
Sbjct: 55 KREISIMKLVRHPCVVRLYEVLASRTKIYIILEYITGGELFDKIVRNGRLSESEARKYFH 114
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAAL-ESKDKLLETSCGSPHYA 192
Q+I G+ YCH+ G+ HRDLKPENLLLD + N+K++DFG++AL E +L+T+CG+P+Y
Sbjct: 115 QLIDGVDYCHSKGVYHRDLKPENLLLDSQGNLKISDFGLSALPEQGVTILKTTCGTPNYV 174
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDE 252
APE++S Y+G +D+WSCGVILY L+ G LPFDE D + L K+ +F P
Sbjct: 175 APEVLSHKGYNGAVADIWSCGVILYVLMAGYLPFDEMD--LPTLYSKIDKAEFSCP--SY 230
Query: 253 ISSEAQDLIARILTVDPEQRIKTREILK 280
+ A+ LI RIL +PE RI EI K
Sbjct: 231 FALGAKSLINRILDPNPETRITIAEIRK 258
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 220 bits (561), Expect = 8e-57
Identities = 119/268 (44%), Positives = 167/268 (61%), Gaps = 15/268 (5%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
IG + LG TLGVG+ GKV + +E G + AVKI+++ + ++G I
Sbjct: 15 IGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQ--KIRSLDVVGK---------I 63
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
REI +KL HP++++LY V T D++MV+EYV GELF+ + + G L E E+ R F+
Sbjct: 64 RREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQ 123
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QI+ G+ YCH +VHRDLKPEN+LLD N K+ADFG++ + S + L TSCGSP+YAA
Sbjct: 124 QILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA 183
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE++SG Y G E D+WS GVILYALL G LPFD D ++ L K+ G F P +
Sbjct: 184 PEVISGRLYAGPEVDIWSSGVILYALLCGTLPFD--DDHVPTLFKKICDGIFYTP--QYL 239
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKH 281
+ L+ +L VDP +R ++I +H
Sbjct: 240 NPSVISLLKHMLQVDPMKRASIKDIREH 267
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 220 bits (561), Expect = 8e-57
Identities = 117/276 (42%), Positives = 170/276 (61%), Gaps = 18/276 (6%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G +++G T+G G+ KV A N G+ A+KI+ K + I
Sbjct: 11 VGKYEVGRTIGEGTFAKVKFARNSETGEPVALKILDKEKVLKHK-----------MAEQI 59
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
REI MKL+ HPNV++LY+V + ++++LEYV GELF+ +V G + E+EA R+F+
Sbjct: 60 RREIATMKLIKHPNVVQLYEVMASKTKIFIILEYVTGGELFDKIVNDGRMKEDEARRYFQ 119
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESK---DKLLETSCGSPH 190
Q+I + YCH+ G+ HRDLKPENLLLD N+K++DFG++AL + D LL TSCG+P+
Sbjct: 120 QLIHAVDYCHSRGVYHRDLKPENLLLDSYGNLKISDFGLSALSQQVRDDGLLHTSCGTPN 179
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
Y APE+++ Y G +D+WSCGV+LY LL G LPFD D N+ NL K+ SG+F P
Sbjct: 180 YVAPEVLNDRGYDGATADMWSCGVVLYVLLAGYLPFD--DSNLMNLYKKISSGEFNCP-- 235
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
+S A LI RIL +P R+ +E+ + +K
Sbjct: 236 PWLSLGAMKLITRILDPNPMTRVTPQEVFEDEWFKK 271
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 219 bits (559), Expect = 1e-56
Identities = 118/279 (42%), Positives = 179/279 (63%), Gaps = 16/279 (5%)
Query: 8 TLKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPD 67
T K +G +++G T+G G+ KV A N G A+KI++KS T++ D
Sbjct: 2 TKKMRRVGKYEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKS-------TILKNRMVD 54
Query: 68 VLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENE 127
I+REI IMK++ HPN++RLY+V + +Y+VLE+V GELF+ +V +G L E+E
Sbjct: 55 Q----IKREISIMKIVRHPNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESE 110
Query: 128 AVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKD-KLLETSC 186
+ ++F+Q++ +++CH G+ HRDLKPENLLLD N+K++DFG++AL + +LL T+C
Sbjct: 111 SRKYFQQLVDAVAHCHCKGVYHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVELLRTTC 170
Query: 187 GSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFE 246
G+P+Y APE++SG Y G +D+WSCGVIL+ +L G LPF E D + L K+ + +F
Sbjct: 171 GTPNYVAPEVLSGQGYDGSAADIWSCGVILFVILAGYLPFSETD--LPGLYRKINAAEFS 228
Query: 247 MPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
P S+E + LI RIL +P+ RI+ + I K P R
Sbjct: 229 CP--PWFSAEVKFLIHRILDPNPKTRIQIQGIKKDPWFR 265
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 219 bits (558), Expect = 2e-56
Identities = 148/449 (32%), Positives = 226/449 (49%), Gaps = 46/449 (10%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G +KL T+G G+ KV +A + G + A+KII K+ N +
Sbjct: 167 VGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLF----------- 215
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
RE+ IMK L+HPN+++LY V ET + LY+VLEY GE+F+ LV G + E EA FR
Sbjct: 216 -REVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFR 274
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QI+ + Y H+ I+HRDLK ENLLLD N+K+ADFG + S L+T CGSP YAA
Sbjct: 275 QIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFCGSPPYAA 334
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+ SG Y G E DVWS GVILY L++G LPFD + N++ L +V GK+ +P +
Sbjct: 335 PELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQ--NLKELRERVLRGKYRIP--FYM 390
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPLSLEG 313
S++ ++L+ + L ++P++R I+K + N+ ED L P +E
Sbjct: 391 STDCENLLKKFLVINPQRRSSLDNIMKDRWM-------------NVGYEDDELKPF-IEP 436
Query: 314 GNQCVDETILQNLVVLWH-GRNKEDIITKL-MEPGANLEKTFYALLHRFKHDNYXXXXXX 371
+DE ++ L+ ++ G NK I+ + E ++ T+ L R +
Sbjct: 437 PKDQIDEQRIEKLIQIFQLGFNKAAILESVEKEKFEDIHATYLLLGERKSDMDASEITMA 496
Query: 372 XXXXXXXSVSSNSLM-----------YVGSLPSPNKSDSPVTTPKKKRTSI---IVASSS 417
S++ +S + +V S + S SP + T+ I A S+
Sbjct: 497 QSLLSHSSINVSSSLGQHPAGVITREHVTSSSASGSSASPSRYSRSSATATGASITAGSA 556
Query: 418 HKRPVSMQKLSSQHSSPVKNGSIGKRLSK 446
+ QK ++P S +R S+
Sbjct: 557 LASAANAQKHQQSSAAPSSGSSSSRRSSQ 585
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 216 bits (551), Expect = 1e-55
Identities = 132/351 (37%), Positives = 193/351 (54%), Gaps = 31/351 (8%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G +KL T+G G+ KV +A + G + A+KII K+ N +
Sbjct: 119 VGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLF----------- 167
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
RE+ IMK L+HPN+++LY V ET + LY+VLEY GE+F+ LV G + E EA FR
Sbjct: 168 -REVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFR 226
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QI+ + Y H+ I+HRDLK ENLLLD N+K+ADFG + S L+T CGSP YAA
Sbjct: 227 QIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFCGSPPYAA 286
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+ SG Y G E DVWS GVILY L++G LPFD + N++ L +V GK+ +P +
Sbjct: 287 PELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQ--NLKELRERVLRGKYRIP--FYM 342
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPLSLEG 313
S++ ++L+ + L ++P++R I+K + N+ ED L P +E
Sbjct: 343 STDCENLLKKFLVINPQRRSSLDNIMKDRWM-------------NVGYEDDELKPF-IEP 388
Query: 314 GNQCVDETILQNLVVLWH-GRNKEDIITKLMEPGANLEKTFYALLHRFKHD 363
+DE ++ L+ ++ G NK I+ + + Y LL K D
Sbjct: 389 PKDQIDEQRIEKLIQIFQLGFNKAAILESVEKEKFEDIHATYLLLGERKSD 439
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 214 bits (546), Expect = 5e-55
Identities = 154/467 (32%), Positives = 241/467 (50%), Gaps = 47/467 (10%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
IG ++L T+G G+ KV +A + G++ AVKII K+ N+ +
Sbjct: 17 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLF----------- 65
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
RE+ IMK+LNHPN+++L++V ET K LY+V+EY GE+F+ LV G + E EA FR
Sbjct: 66 -REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFR 124
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QI+ + YCH IVHRDLK ENLLLD N+K+ADFG + + L+T CGSP YAA
Sbjct: 125 QIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAA 184
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+ G Y G E DVWS GVILY L++G LPFD + N++ L +V GK+ +P +
Sbjct: 185 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQ--NLKELRERVLRGKYRIP--FYM 240
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPLSLEG 313
S++ ++L+ + L ++P +R +I+K + N+ ED L P +E
Sbjct: 241 STDCENLLKKFLILNPSKRGTLEQIMKDRWM-------------NVGHEDDELKPY-VEP 286
Query: 314 GNQCVDETILQNLVVLWHGRNKEDIITKLMEPGANLEKTFYALLHRFKHDNYXXXXXXXX 373
D + +V + G +E+I L+ N Y LL +K
Sbjct: 287 LPDYKDPRRTELMVSM--GYTREEIQDSLVGQRYNEVMATYLLL-GYKSSELEGDTITLK 343
Query: 374 XXXXXSVSSNSLMYVGSLPSPNKSDSPVTTPKKKRTS-----IIVASSSHKRPVSMQKLS 428
++++S + PS S PK++R S I S+S+ + Q +
Sbjct: 344 PRPSADLTNSSAQF----PSHKVQRSVSANPKQRRFSDQAGPAIPTSNSYSK--KTQSNN 397
Query: 429 SQHSSPVKNGSIGKRLSKT--FPSNKRISQLVSNSSSPTPAAHKRVS 473
+++ P ++ G++ S T P++ + L ++PTP+ + +S
Sbjct: 398 AENKRPEEDRESGRKASSTAKVPASP-LPGLERKKTTPTPSTNSVLS 443
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 214 bits (546), Expect = 5e-55
Identities = 154/467 (32%), Positives = 241/467 (50%), Gaps = 47/467 (10%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
IG ++L T+G G+ KV +A + G++ AVKII K+ N+ +
Sbjct: 17 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLF----------- 65
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
RE+ IMK+LNHPN+++L++V ET K LY+V+EY GE+F+ LV G + E EA FR
Sbjct: 66 -REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFR 124
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QI+ + YCH IVHRDLK ENLLLD N+K+ADFG + + L+T CGSP YAA
Sbjct: 125 QIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAA 184
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+ G Y G E DVWS GVILY L++G LPFD + N++ L +V GK+ +P +
Sbjct: 185 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQ--NLKELRERVLRGKYRIP--FYM 240
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPLSLEG 313
S++ ++L+ + L ++P +R +I+K + N+ ED L P +E
Sbjct: 241 STDCENLLKKFLILNPSKRGTLEQIMKDRWM-------------NVGHEDDELKPY-VEP 286
Query: 314 GNQCVDETILQNLVVLWHGRNKEDIITKLMEPGANLEKTFYALLHRFKHDNYXXXXXXXX 373
D + +V + G +E+I L+ N Y LL +K
Sbjct: 287 LPDYKDPRRTELMVSM--GYTREEIQDSLVGQRYNEVMATYLLL-GYKSSELEGDTITLK 343
Query: 374 XXXXXSVSSNSLMYVGSLPSPNKSDSPVTTPKKKRTS-----IIVASSSHKRPVSMQKLS 428
++++S + PS S PK++R S I S+S+ + Q +
Sbjct: 344 PRPSADLTNSSAQF----PSHKVQRSVSANPKQRRFSDQAGPAIPTSNSYSK--KTQSNN 397
Query: 429 SQHSSPVKNGSIGKRLSKT--FPSNKRISQLVSNSSSPTPAAHKRVS 473
+++ P ++ G++ S T P++ + L ++PTP+ + +S
Sbjct: 398 AENKRPEEDRESGRKASSTAKVPASP-LPGLERKKTTPTPSTNSVLS 443
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 214 bits (545), Expect = 6e-55
Identities = 115/274 (41%), Positives = 171/274 (61%), Gaps = 16/274 (5%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G ++LG TLG G+ KV A N G A+K+I K + MI I
Sbjct: 28 VGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVIDKE--KVLKNKMIAQ---------I 76
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
+REI MKL+ HPNV+R+++V + +Y VLE+V GELF+ + G L E+EA ++F+
Sbjct: 77 KREISTMKLIKHPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQ 136
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAAL-ESKDKLLETSCGSPHYA 192
Q+I + YCH+ G+ HRDLKPENLLLD +K++DFG++AL + +D LL T+CG+P+Y
Sbjct: 137 QLINAVDYCHSRGVYHRDLKPENLLLDANGALKVSDFGLSALPQQEDGLLHTTCGTPNYV 196
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDE 252
APE+++ Y G ++D+WSCGVIL+ L+ G LPF ED N+ +L K+ +F P
Sbjct: 197 APEVINNKGYDGAKADLWSCGVILFVLMAGYLPF--EDSNLTSLYKKIFKAEFTCP--PW 252
Query: 253 ISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
S+ A+ LI RIL +P RI E++++ +K
Sbjct: 253 FSASAKKLIKRILDPNPATRITFAEVIENEWFKK 286
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 214 bits (544), Expect = 8e-55
Identities = 112/271 (41%), Positives = 169/271 (62%), Gaps = 17/271 (6%)
Query: 15 GPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIE 74
G ++LG LG G+ KV A + GQ AVKI++K + L I+
Sbjct: 19 GKYELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPA----------LANNIK 68
Query: 75 REIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQ 134
REI IM+ L+HPN+++L++V T ++ +E+V+ GELFN + + G L E+ + R+F+Q
Sbjct: 69 REISIMRRLSHPNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQ 128
Query: 135 IIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESK---DKLLETSCGSPHY 191
+I + YCHA G+ HRDLKPENLL+D N+K++DFG++AL + D LL T CG+P Y
Sbjct: 129 LISAVGYCHARGVYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAY 188
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDD 251
APEI+S Y G + DVWSCG++L+ L+ G LPF+ D N+ N+ K+ G++ P
Sbjct: 189 VAPEILSKKGYEGAKVDVWSCGIVLFVLVAGYLPFN--DPNVMNMYKKIYKGEYRFP--R 244
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKHP 282
+S + + ++R+L ++PE RI EILK P
Sbjct: 245 WMSPDLKRFVSRLLDINPETRITIDEILKDP 275
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 213 bits (541), Expect = 2e-54
Identities = 154/467 (32%), Positives = 240/467 (50%), Gaps = 47/467 (10%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
IG ++L T+G G+ KV +A + G++ AVKII K+ N+ +
Sbjct: 50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLF----------- 98
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
RE+ IMK+LNHPN+++L++V ET K LY+V+EY GE+F+ LV G + E EA FR
Sbjct: 99 -REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFR 157
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QI+ + YCH IVHRDLK ENLLLD N+K+ADFG + + L+T CGSP YAA
Sbjct: 158 QIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAA 217
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+ G Y G E DVWS GVILY L++G LPFD + N++ L +V GK+ +P +
Sbjct: 218 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQ--NLKELRERVLRGKYRIP--FYM 273
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPLSLEG 313
S++ ++L+ + L ++P +R +I+K + N+ ED L P +E
Sbjct: 274 STDCENLLKKFLILNPSKRGTLEQIMKDRWM-------------NVGHEDDELKPY-VEP 319
Query: 314 GNQCVDETILQNLVVLWHGRNKEDIITKLMEPGANLEKTFYALLHRFKHDNYXXXXXXXX 373
D + +V + G +E+I L+ N Y LL +K
Sbjct: 320 LPDYKDPRRTELMVSM--GYTREEIQDSLVGQRYNEVMATYLLL-GYKSSELEGDTITLK 376
Query: 374 XXXXXSVSSNSLMYVGSLPSPNKSDSPVTTPKKKRTS-----IIVASSSHKRPVSMQKLS 428
++++S PS S PK++R S I S+S+ + Q +
Sbjct: 377 PRPSADLTNSS----APSPSHKVQRSVSANPKQRRFSDQAGPAIPTSNSYSK--KTQSNN 430
Query: 429 SQHSSPVKNGSIGKRLSKT--FPSNKRISQLVSNSSSPTPAAHKRVS 473
+++ P ++ G++ S T P++ + L ++PTP+ + +S
Sbjct: 431 AENKRPEEDRESGRKASSTAKVPASP-LPGLERKKTTPTPSTNSVLS 476
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 213 bits (541), Expect = 2e-54
Identities = 116/272 (42%), Positives = 165/272 (60%), Gaps = 15/272 (5%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
IG + + T+G G+ G V + G A+KI+++ G+ N+ D L
Sbjct: 21 IGNFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNL---- 76
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
+ L HP++ RL+ V T D+++V+E V GELF+ + +G LP E+ R+F+
Sbjct: 77 -------QKLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQ 129
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QII G+SYCH IVHRDLKPENLLLD N+K+ADFG++ + LL T+CGSP+YAA
Sbjct: 130 QIISGVSYCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNYMTDGDLLSTACGSPNYAA 189
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE++S Y G E D+WSCGVILYA+L G LPFD D N+ L K++SG++ +P E
Sbjct: 190 PELISNKLYVGPEVDLWSCGVILYAMLCGTLPFD--DQNVPTLFAKIKSGRYTVPYSME- 246
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
+A DLI+ +L VDP +R + I+ H R
Sbjct: 247 -KQAADLISTMLQVDPVKRADVKRIVNHSWFR 277
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 212 bits (540), Expect = 2e-54
Identities = 122/303 (40%), Positives = 179/303 (58%), Gaps = 20/303 (6%)
Query: 9 LKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDV 68
+KG +G ++LG TLG G++ KV A + G+ A+KII KS
Sbjct: 3 IKGMRVGKYELGRTLGEGNSAKVKFAIDTLTGESFAIKIIEKSCITRLN----------- 51
Query: 69 LPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEA 128
+ + I+REI +K+L HPN++RL++V + +YMVLE V G+LF+ +V +G L E +
Sbjct: 52 VSFQIKREIRTLKVLKHPNIVRLHEVLASKTKIYMVLECVTGGDLFDRIVSKGKLSETQG 111
Query: 129 VRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALES---KDKLLETS 185
+ F+Q+I G+SYCH G+ HRDLK EN+LLD K ++K+ DFG++AL +D LL T+
Sbjct: 112 RKMFQQLIDGVSYCHNKGVFHRDLKLENVLLDAKGHIKITDFGLSALSQHYREDGLLHTT 171
Query: 186 CGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKF 245
CGSP+Y APE+++ Y G SD+WSCGVILY +LTG LPFD D N+ + K+ G
Sbjct: 172 CGSPNYVAPEVLANEGYDGAASDIWSCGVILYVILTGCLPFD--DANLAVICRKIFKG-- 227
Query: 246 EMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK--YPSIKDSKSIRNLPRED 303
+ P IS A+ +I R+L +P R+ I H + PS D L +ED
Sbjct: 228 DPPIPRWISLGAKTMIKRMLDPNPVTRVTIAGIKAHDWFKHDYTPSNYDDDDDVYLIQED 287
Query: 304 TYL 306
++
Sbjct: 288 VFM 290
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 211 bits (536), Expect = 7e-54
Identities = 118/279 (42%), Positives = 171/279 (60%), Gaps = 18/279 (6%)
Query: 4 NGITTLKGDT--IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMI 61
N IT+ + IG ++L T+G G+ KV +A + G++ AVKII K+ N +
Sbjct: 45 NSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKL 104
Query: 62 GGNDPDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERG 121
RE+ IMK+LNHPN+++L++V ET K LY+V+EY GE+F+ LV G
Sbjct: 105 F------------REVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHG 152
Query: 122 PLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKL 181
+ E EA FRQI+ + YCH IVHRDLK ENLLLD N+K+ADFG + +
Sbjct: 153 RMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNK 212
Query: 182 LETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQ 241
L+T CGSP YAAPE+ G Y G E DVWS GVILY L++G LPFD + N++ L +V
Sbjct: 213 LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQ--NLKELRERVL 270
Query: 242 SGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILK 280
GK+ +P +S++ ++L+ ++L ++P +R +I+K
Sbjct: 271 RGKYRIP--FYMSTDCENLLKKLLVLNPIKRGSLEQIMK 307
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 211 bits (536), Expect = 7e-54
Identities = 115/281 (40%), Positives = 166/281 (58%), Gaps = 26/281 (9%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKS-IFNAQGSTMIGGNDPDVLPYGIER 75
+ +G LG G+ KV + G A+K+I K +F +G + IER
Sbjct: 15 YNIGRLLGTGNFAKVYHGTEISTGDDVAIKVIKKDHVFKRRG-----------MMEQIER 63
Query: 76 EIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
EI +M+LL HPNV+ L +V T K ++ V+EYV GELF ++ G LPE+ A ++F+Q+
Sbjct: 64 EIAVMRLLRHPNVVELREVMATKKKIFFVMEYVNGGELFEMIDRDGKLPEDLARKYFQQL 123
Query: 136 IIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAAL----------ESKDKLLETS 185
I + +CH+ G+ HRD+KPENLLLD + ++K+ DFG++AL S D LL T
Sbjct: 124 ISAVDFCHSRGVFHRDIKPENLLLDGEGDLKVTDFGLSALMMPEGLGGRRGSSDDLLHTR 183
Query: 186 CGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKF 245
CG+P Y APE++ Y G +D+WSCG++LYALL G LPF +E N+ L K+ +
Sbjct: 184 CGTPAYVAPEVLRNKGYDGAMADIWSCGIVLYALLAGFLPFIDE--NVMTLYTKIFKAEC 241
Query: 246 EMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
E P S E+++L++R+L DPEQRI EI P RK
Sbjct: 242 EFP--PWFSLESKELLSRLLVPDPEQRISMSEIKMIPWFRK 280
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 210 bits (535), Expect = 9e-54
Identities = 160/513 (31%), Positives = 244/513 (47%), Gaps = 43/513 (8%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G ++L T+G G++ KV +A + G++ A+KII K+ N +
Sbjct: 56 VGNYRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLF----------- 104
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
RE+ IMK LNHPN+++L++V ET K LY+V+EY GE+F+ LV G + E EA FR
Sbjct: 105 -REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFR 163
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QI+ + YCH IVHRDLK ENLLLD + N+K+ADFG + + L+T CGSP YAA
Sbjct: 164 QIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAA 223
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+ G Y G E D+WS GVILY L++G LPFD N++ L +V GK+ +P +
Sbjct: 224 PELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGH--NLKELRERVLRGKYRVP--FYM 279
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPLSLEG 313
S++ + ++ R L ++P +R +I+K + N+ E L P + E
Sbjct: 280 STDCESILRRFLVLNPAKRCTLEQIMKDKWI-------------NIGYEGEELKPYT-EP 325
Query: 314 GNQCVDETILQNLVVLWHGRNKEDIITKLMEPGANLEKTFYALLHRFKH---DNYXXXXX 370
D ++ V++ G +E+I L N Y LL R D
Sbjct: 326 EEDFGDTKRIE--VMVGMGYTREEIKESLTSQKYNEVTATYLLLGRKTEEGGDRGAPGLA 383
Query: 371 XXXXXXXXSVSSNSLMYVGSLPSPNKSDSPVTTPKKKRTSIIVASSSHKRPVSMQKLSSQ 430
++ + G+ S + S T +++R S S S+
Sbjct: 384 LARVRAPSDTTNGTSSSKGTSHSKGQRSSSSTYHRQRRHSDFCGPSPAPLHPKRSPTSTG 443
Query: 431 HSSPVKNGSIGKRLS-KTFPSNKR----ISQLVSNSSSPTPA---AHKRVSRINDSAAPP 482
+ + G++ S T S R S +VS++ +P A ++ S + PP
Sbjct: 444 EAELKEERLPGRKASCSTAGSGSRGLPPSSPMVSSAHNPNKAEIPERRKDSTSTPNNLPP 503
Query: 483 VPKEMLRDYKRQSKRQSKRFSLLPNMKRGSITT 515
Y + ++R SLLPN K S T
Sbjct: 504 SMMTRRNTYVCTERPGAERPSLLPNGKENSSGT 536
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 210 bits (534), Expect = 1e-53
Identities = 113/265 (42%), Positives = 163/265 (60%), Gaps = 16/265 (6%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
++L TLG G+ GKV A G+ A+K I K ++ D++ I RE
Sbjct: 55 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIK---------DEQDMVH--IRRE 103
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I IM LNHP+++ +Y+V+E + +++EY KGEL++ + ER L E E FFRQI+
Sbjct: 104 IEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIV 163
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEI 196
+ YCH G+VHRDLK EN+LLD N+K+ADFG++ L KDK L+T CGSP YA+PEI
Sbjct: 164 SAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEI 223
Query: 197 VSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISSE 256
V+G PY G E D W+ GV+LY L+ G +PFD D +NL+ ++ SG++ P S+
Sbjct: 224 VNGRPYRGPEVDSWALGVLLYTLVYGTMPFDGFDH--KNLIRQISSGEYREPTQ---PSD 278
Query: 257 AQDLIARILTVDPEQRIKTREILKH 281
A+ LI +L V+P++R +I H
Sbjct: 279 ARGLIRWMLMVNPDRRATIEDIANH 303
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 209 bits (531), Expect = 3e-53
Identities = 115/276 (41%), Positives = 163/276 (58%), Gaps = 16/276 (5%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G ++L T+G G+ V +A N + A+KII K+ N +
Sbjct: 38 VGYYELEKTIGKGNFAVVKLATNIVTKTKVAIKIIDKTCLNEEYLNKTF----------- 86
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
REI I+K L HP++ RLY+V E+ +Y+V EY GE+F+ LV G + E EA R F
Sbjct: 87 -REIAILKSLRHPHITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANGRMKEPEAARVFT 145
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
Q++ + YCH G+VHRDLK EN+LLD N+KLADFG + + L+T CGSP YAA
Sbjct: 146 QLVSAVHYCHRRGVVHRDLKAENVLLDKDMNIKLADFGFSNHYEEGATLKTWCGSPPYAA 205
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+ GL Y G +SD+WS GV+LYAL+ G LPFD + I L +V GKF +P +
Sbjct: 206 PEVFQGLEYDGPKSDIWSLGVVLYALVCGALPFDGK--TILELKSRVVLGKFRIP--FFM 261
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPS 289
S E + LI +L V+P++R ++I+KH L ++ S
Sbjct: 262 SQECEQLIRNMLVVEPDRRYTIKQIIKHRWLSEWQS 297
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 208 bits (530), Expect = 3e-53
Identities = 114/275 (41%), Positives = 168/275 (60%), Gaps = 18/275 (6%)
Query: 15 GPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIE 74
G +++G LG G+ KV G+ A+K+I+K + M I+
Sbjct: 10 GKYEMGRLLGKGTFAKVYYGKEIIGGECVAIKVINKDQVMKRPGMM----------EQIK 59
Query: 75 REIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQ 134
REI IMKL+ HPN++ L +V T ++ V+E+V+ GELF + +G L E+ A R+F+Q
Sbjct: 60 REISIMKLVRHPNIVELKEVMATKTKIFFVMEFVKGGELF-CKISKGKLHEDAARRYFQQ 118
Query: 135 IIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALES---KDKLLETSCGSPHY 191
+I + YCH+ G+ HRDLKPENLLLD ++K++DFG++AL +D LL T CG+P Y
Sbjct: 119 LISAVDYCHSRGVSHRDLKPENLLLDENGDLKISDFGLSALPEQILQDGLLHTQCGTPAY 178
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDD 251
APE++ Y G ++D+WSCGV+LY LL G LPF +E N+ N+ K+ FE P
Sbjct: 179 VAPEVLKKKGYDGAKADIWSCGVVLYVLLAGCLPFQDE--NLMNMYRKIFRADFEFP--P 234
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
S EA+ LI+++L VDP++RI I++ P LRK
Sbjct: 235 WFSPEARRLISKLLVVDPDRRISIPAIMRTPWLRK 269
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 208 bits (530), Expect = 3e-53
Identities = 111/271 (40%), Positives = 163/271 (59%), Gaps = 16/271 (5%)
Query: 9 LKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDV 68
+ G+ G +K+ TLG G+ KV +A + G++ A+K+I K+ N +
Sbjct: 90 VNGNGNGVYKIIKTLGKGNFAKVKLAIHVPTGREVAIKVIDKTQLNTSARQKL------- 142
Query: 69 LPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEA 128
RE+ IMKLLNHPN++RL+ V E+ + LY+V+EY +GELF+ LV+ G + E +A
Sbjct: 143 -----YREVKIMKLLNHPNIVRLFQVIESERTLYLVMEYASRGELFDHLVKNGRMRERDA 197
Query: 129 VRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGS 188
FRQ++ I YCH+ +VHRDLK ENLLLD N+K+ADFG + LET CGS
Sbjct: 198 RVIFRQLVSAIQYCHSKFVVHRDLKAENLLLDQHMNIKIADFGFGNTFDPNAQLETFCGS 257
Query: 189 PHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMP 248
P YAAPE+ G Y G E D WS GV+LY L++G LPFD G ++ L +V GK+ +P
Sbjct: 258 PPYAAPELFMGRKYAGPEVDAWSLGVVLYTLVSGSLPFD--GGTLKELRERVLRGKYRVP 315
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREIL 279
IS + ++L+ + L ++P +R ++
Sbjct: 316 --YYISMDCENLMRKFLVLNPAKRTSLSAVM 344
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 208 bits (530), Expect = 3e-53
Identities = 114/271 (42%), Positives = 161/271 (59%), Gaps = 16/271 (5%)
Query: 9 LKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDV 68
+ G+ G +K+ TLG G+ KV +A + G++ A+K+I K+ N +
Sbjct: 55 VNGNGYGVYKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALNT------------I 102
Query: 69 LPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEA 128
+ RE+ IMK LNHPN++RL V E+ + LY+V+EYV GELFN LV+ G + E +A
Sbjct: 103 ARQKLYREVNIMKKLNHPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDA 162
Query: 129 VRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGS 188
FRQ++ I YCH+ IVHRDLK ENLLLD + +K+ADFG + LET CGS
Sbjct: 163 RVLFRQLVSAIEYCHSKSIVHRDLKAENLLLDQQMKLKIADFGFSTTFEPKAPLETFCGS 222
Query: 189 PHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMP 248
P YAAPE+ G Y G E D WS GV+LY L++G LPFD N++ L +V GK+ +P
Sbjct: 223 PPYAAPELFRGKKYSGPEVDSWSLGVVLYTLVSGSLPFD--GTNLKELRDRVLRGKYRVP 280
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREIL 279
+S E + LI + L ++P QR ++
Sbjct: 281 --YYVSIECESLIRKFLVLNPTQRTSLSAVM 309
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 208 bits (529), Expect = 4e-53
Identities = 110/273 (40%), Positives = 169/273 (61%), Gaps = 19/273 (6%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+++G LG G+ GKV T G+ A+KII+K +G + I+RE
Sbjct: 15 YEMGRLLGKGTFGKVYYGKEITTGESVAIKIINKDQVKREG-----------MMEQIKRE 63
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I IM+L+ HPN++ L +V T ++ ++EYV+ GELF+ +V +G L E+ A ++F+Q+I
Sbjct: 64 ISIMRLVRHPNIVELKEVMATKTKIFFIMEYVKGGELFSKIV-KGKLKEDSARKYFQQLI 122
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALES---KDKLLETSCGSPHYAA 193
+ +CH+ G+ HRDLKPENLL+D ++K++DFG++AL +D LL T CG+P Y A
Sbjct: 123 SAVDFCHSRGVSHRDLKPENLLVDENGDLKVSDFGLSALPEQILQDGLLHTQCGTPAYVA 182
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE++ Y G + D+WSCG+ILY LL G LPF +E N+ + K+ +FE P
Sbjct: 183 PEVLRKKGYDGAKGDIWSCGIILYVLLAGFLPFQDE--NLMKMYRKIFKSEFEYP--PWF 238
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
S E++ LI+++L VDP +RI I++ P RK
Sbjct: 239 SPESKRLISKLLVVDPNKRISIPAIMRTPWFRK 271
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 207 bits (528), Expect = 6e-53
Identities = 123/299 (41%), Positives = 184/299 (61%), Gaps = 25/299 (8%)
Query: 1 MNGNGITTLKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTM 60
M+ NGI ++ ++LG LG G+ KV A N G+ A+K+I K Q
Sbjct: 1 MDKNGIVLMR-----KYELGRLLGQGTFAKVYHARNIKTGESVAIKVIDK-----QKVAK 50
Query: 61 IGGNDPDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVER 120
+G D I+REI +M+L+ HP+V+ L++V + +Y +EYV+ GELF+ V +
Sbjct: 51 VGLIDQ------IKREISVMRLVRHPHVVFLHEVMASKTKIYFAMEYVKGGELFDK-VSK 103
Query: 121 GPLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAAL-ESK- 178
G L EN A ++F+Q+I I YCH+ G+ HRDLKPENLLLD ++K++DFG++AL ESK
Sbjct: 104 GKLKENIARKYFQQLIGAIDYCHSRGVYHRDLKPENLLLDENGDLKISDFGLSALRESKQ 163
Query: 179 -DKLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLL 237
D LL T+CG+P Y APE++ Y G ++DVWSCGV+LY LL G LPF E+ N+ +
Sbjct: 164 QDGLLHTTCGTPAYVAPEVIGKKGYDGAKADVWSCGVVLYVLLAGFLPFHEQ--NLVEMY 221
Query: 238 LKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK-YPSIKDSKS 295
K+ G+F+ P + E + L++RIL +P RIK +I+++ +K + I+ KS
Sbjct: 222 RKITKGEFKCP--NWFPPEVKKLLSRILDPNPNSRIKIEKIMENSWFQKGFKKIETPKS 278
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 206 bits (525), Expect = 1e-52
Identities = 113/267 (42%), Positives = 165/267 (61%), Gaps = 16/267 (5%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
IG ++L T+G G+ KV +A + G++ A+KII K+ N +
Sbjct: 53 IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF----------- 101
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
RE+ IMK+LNHPN+++L++V ET K LY+++EY G++F+ LV G + E EA FR
Sbjct: 102 -REVRIMKILNHPNIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFR 160
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QI+ + YCH IVHRDLK ENLLLD N+K+ADFG + + L+T CGSP YAA
Sbjct: 161 QIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAA 220
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+ G Y G E DVWS GVILY L++G LPFD + N++ L +V GK+ +P +
Sbjct: 221 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQ--NLKELRERVLRGKYRIP--FYM 276
Query: 254 SSEAQDLIARILTVDPEQRIKTREILK 280
S++ ++L+ R L ++P +R +I+K
Sbjct: 277 STDCENLLKRFLVLNPIKRGTLEQIMK 303
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 205 bits (522), Expect = 3e-52
Identities = 114/273 (41%), Positives = 166/273 (60%), Gaps = 19/273 (6%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+++G LG G+ KV A + G A+K+I K G T I+RE
Sbjct: 12 YEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTE-----------QIKRE 60
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I M+LL HPN++ L++V T +Y V+E+V+ GELFN V G L E+ A ++F+Q++
Sbjct: 61 ISAMRLLRHPNIVELHEVMATKSKIYFVMEHVKGGELFNK-VSTGKLREDVARKYFQQLV 119
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALES---KDKLLETSCGSPHYAA 193
+ +CH+ G+ HRDLKPENLLLD N+K++DFG++AL +D LL T+CG+P Y A
Sbjct: 120 RAVDFCHSRGVCHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVA 179
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE++S Y GF++DVWSCGVIL+ LL G LPF D N+ L K+ GK E+ + +
Sbjct: 180 PEVISRNGYDGFKADVWSCGVILFVLLAGYLPF--RDSNLMELYKKI--GKAEVKFPNWL 235
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
+ A+ L+ RIL +P R+ T +I+K RK
Sbjct: 236 APGAKRLLKRILDPNPNTRVSTEKIMKSSWFRK 268
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 205 bits (522), Expect = 3e-52
Identities = 118/294 (40%), Positives = 173/294 (58%), Gaps = 20/294 (6%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G ++LG LG G+ KV +A N G + A+K+I K G L I
Sbjct: 71 MGKYELGKLLGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSG-----------LVAHI 119
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
+REI I++ + HP ++ L++V T +Y V+EYV GELFN V +G LPE A R+F+
Sbjct: 120 KREISILRRVRHPYIVHLFEVMATKSKIYFVMEYVGGGELFNT-VAKGRLPEETARRYFQ 178
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALES---KDKLLETSCGSPH 190
Q+I +S+CH G+ HRDLKPENLLLD+K N+K++DFG++A+ +D L T CG+P
Sbjct: 179 QLISSVSFCHGRGVYHRDLKPENLLLDNKGNLKVSDFGLSAVAEQLRQDGLCHTFCGTPA 238
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
Y APE+++ Y ++DVWSCGVIL+ L+ G +PF D NI + K+ G+F P
Sbjct: 239 YIAPEVLTRKGYDAAKADVWSCGVILFVLMAGHIPF--YDKNIMVMYKKIYKGEFRCP-- 294
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK-YPSIKDSKSIRNLPRED 303
SS+ L+ R+L +P+ RI EI+K+ +K + +K L RED
Sbjct: 295 RWFSSDLVRLLTRLLDTNPDTRITIPEIMKNRWFKKGFKHVKFYIEDDKLCRED 348
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 204 bits (520), Expect = 5e-52
Identities = 113/277 (40%), Positives = 168/277 (59%), Gaps = 20/277 (7%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKS-IFNAQGSTMIGGNDPDVLPYG 72
+G +++G TLG GS KV A N G QAA+KI+ + +F + +
Sbjct: 16 VGNYEMGRTLGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRHK------------MVEQ 63
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
++REI MKL+ HPNV+ + +V + +Y+VLE V GELF+ + ++G L E+EA R+F
Sbjct: 64 LKREISTMKLIKHPNVVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRLKEDEARRYF 123
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALE---SKDKLLETSCGSP 189
+Q+I + YCH+ G+ HRDLKPENL+LD +K++DFG++A +D LL T+CG+P
Sbjct: 124 QQLINAVDYCHSRGVYHRDLKPENLILDANGVLKVSDFGLSAFSRQVREDGLLHTACGTP 183
Query: 190 HYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPG 249
+Y APE++S Y G +DVWSCGVIL+ L+ G LPFDE N+ L ++ +F P
Sbjct: 184 NYVAPEVLSDKGYDGAAADVWSCGVILFVLMAGYLPFDEP--NLMTLYKRICKAEFSCP- 240
Query: 250 DDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
S A+ +I RIL +P RI E+L+ +K
Sbjct: 241 -PWFSQGAKRVIKRILEPNPITRISIAELLEDEWFKK 276
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 204 bits (519), Expect = 6e-52
Identities = 125/302 (41%), Positives = 174/302 (57%), Gaps = 26/302 (8%)
Query: 10 KGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVL 69
KG +G ++LG TLG G+ GKV A + G AVKII KS ++
Sbjct: 13 KGMRLGKYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSL--------- 63
Query: 70 PYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAV 129
I+REI +K+L HP+++RL++V + + MV+E V GELF+ +V G L E +
Sbjct: 64 --QIKREIRTLKMLKHPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGR 121
Query: 130 RFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALES---KDKLLETSC 186
+ F+Q+I GISYCH+ G+ HRDLK EN+LLD K ++K+ DFG++AL D LL T+C
Sbjct: 122 KMFQQLIDGISYCHSKGVFHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLHTTC 181
Query: 187 GSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFE 246
GSP+Y APE+++ Y G SD+WSCGVILY +LTG LPFD D N+ L K+ G +
Sbjct: 182 GSPNYVAPEVLANRGYDGAASDIWSCGVILYVILTGCLPFD--DRNLAVLYQKICKG--D 237
Query: 247 MPGDDEISSEAQDLIARILTVDPEQR-----IKTREILKHPLLRKYPSIKDSKSIRNLPR 301
P +S A+ +I R+L +P R IK E K L PSI D +
Sbjct: 238 PPIPRWLSPGARTMIKRMLDPNPVTRITVVGIKASEWFK---LEYIPSIPDDDDEEEVDT 294
Query: 302 ED 303
+D
Sbjct: 295 DD 296
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 204 bits (519), Expect = 6e-52
Identities = 113/266 (42%), Positives = 163/266 (60%), Gaps = 16/266 (6%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
IG +KL T+G G+ KV +A + G++ A+KII K+ N GS +
Sbjct: 148 IGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNP-GSLQ-----------KL 195
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
RE+ IMK+L+HPN+++L+ V ET K LY+++EY GE+F+ LV G + E EA FR
Sbjct: 196 FREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFR 255
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QI+ + YCH I+HRDLK ENLLLD + N+K+ADFG + + L+T CGSP YAA
Sbjct: 256 QIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAA 315
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+ G Y G E DVWS GVILY L++G LPFD +R L +V GK+ +P +
Sbjct: 316 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD--GSTLRELRERVLRGKYRIP--FYM 371
Query: 254 SSEAQDLIARILTVDPEQRIKTREIL 279
S++ ++L+ + L ++P +R I+
Sbjct: 372 STDCENLLRKFLVLNPAKRASLETIM 397
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 200 bits (509), Expect = 9e-51
Identities = 116/291 (39%), Positives = 171/291 (57%), Gaps = 20/291 (6%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+++G LG GS KV +A N G+ A+K+I K G L I+RE
Sbjct: 57 YEIGKLLGHGSFAKVYLARNIHSGEDVAIKVIDKEKIVKSG-----------LAGHIKRE 105
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I I++ + HP ++ L +V T +Y+V+EYV GEL+N V RG L E A R+F+Q+I
Sbjct: 106 ISILRRVRHPYIVHLLEVMATKTKIYIVMEYVRGGELYNT-VARGRLREGTARRYFQQLI 164
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDK---LLETSCGSPHYAA 193
+++CH+ G+ HRDLK ENLLLD K NVK++DFG++ + + K + +T CG+P Y A
Sbjct: 165 SSVAFCHSRGVYHRDLKLENLLLDDKGNVKVSDFGLSVVSEQLKQEGICQTFCGTPAYLA 224
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+++ Y G ++D+WSCGVIL+ L+ G LPFD D NI + K+ G+F+ P
Sbjct: 225 PEVLTRKGYEGAKADIWSCGVILFVLMAGYLPFD--DKNILVMYTKIYKGQFKCP--KWF 280
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRK-YPSIKDSKSIRNLPRED 303
S E L+ R+L +P+ RI EI+KH +K + +K L RED
Sbjct: 281 SPELARLVTRMLDTNPDTRITIPEIMKHRWFKKGFKHVKFYIENDKLCRED 331
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 200 bits (508), Expect = 1e-50
Identities = 113/303 (37%), Positives = 176/303 (57%), Gaps = 24/303 (7%)
Query: 10 KGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVL 69
+G G +++G +G G+ KV + GQ A+K++SK G + GN
Sbjct: 15 RGQLFGKYEVGKLVGCGAFAKVYHGRSTATGQSVAIKVVSKQRLQKGG---LNGN----- 66
Query: 70 PYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAV 129
I+REI IM L HP+++RL++V T ++ V+E+ + GELF V +G E+ +
Sbjct: 67 ---IQREIAIMHRLRHPSIVRLFEVLATKSKIFFVMEFAKGGELF-AKVSKGRFCEDLSR 122
Query: 130 RFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESK---DKLLETSC 186
R+F+Q+I + YCH+ GI HRDLKPENLLLD K ++K++DFG++AL + D LL T C
Sbjct: 123 RYFQQLISAVGYCHSRGIFHRDLKPENLLLDEKLDLKISDFGLSALTDQIRPDGLLHTLC 182
Query: 187 GSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFE 246
G+P Y APE+++ Y G + D+WSCG+IL+ L G LPF+ D N+ + K+ G+F
Sbjct: 183 GTPAYVAPEVLAKKGYDGAKIDIWSCGIILFVLNAGYLPFN--DHNLMVMYRKIYKGEFR 240
Query: 247 MPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSK-----SIRNLPR 301
+P S + + L+ R+L +P+ RI EI+ P ++ + SK S LP
Sbjct: 241 IP--KWTSPDLRRLLTRLLDTNPQTRITIEEIIHDPWFKQGYDDRMSKFHLEDSDMKLPA 298
Query: 302 EDT 304
++T
Sbjct: 299 DET 301
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 198 bits (504), Expect = 3e-50
Identities = 110/268 (41%), Positives = 155/268 (57%), Gaps = 16/268 (5%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G + + TLG G+ V + + + A+KII KS +A I
Sbjct: 17 VGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKI------------ 64
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
RE+ IMK+L+HP++++LY V ET LY+V EY + GE+F+ L G L E+EA R F
Sbjct: 65 YREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFW 124
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QI+ + YCH IVHRDLK ENLLLD+ N+K+ADFG +LL T CGSP YAA
Sbjct: 125 QILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAA 184
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+ G Y G + D+WS GV+LY L+ G LPFD + L +V G+F +P +
Sbjct: 185 PEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFD--GPTLPILRQRVLEGRFRIP--YFM 240
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKH 281
S + + LI R+L +DP +R+ +I +H
Sbjct: 241 SEDCEHLIRRMLVLDPSKRLTIAQIKEH 268
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 198 bits (504), Expect = 3e-50
Identities = 108/265 (40%), Positives = 156/265 (58%), Gaps = 16/265 (6%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+++ LG G+ GKV +AY+ ++ AVK+I KS ++ + I RE
Sbjct: 75 FEITKKLGSGTYGKVSLAYDHKFDREVAVKLIKKSAIESKADLV-----------RIRRE 123
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I IM LNHPN++++Y+V+E + +V+EY GEL++ + G LPE EA R FRQI
Sbjct: 124 IRIMSALNHPNIIQIYEVFENKDKIILVMEYSSGGELYDYVSRCGSLPEAEARRIFRQIT 183
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEI 196
+ YCH + HRDLK EN+LLD N K+ADFG++ + LL T CGSP YA+PEI
Sbjct: 184 SAVLYCHKHRVAHRDLKLENILLDQNNNAKIADFGLSNYFADKNLLTTFCGSPLYASPEI 243
Query: 197 VSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISSE 256
++G PY G E D WS G++LY L+ G +PFD D N ++ +++ G + P E S
Sbjct: 244 INGTPYKGPEVDCWSLGILLYTLVYGSMPFDGRDFN--RMVRQIKRGAYFEP---ETPST 298
Query: 257 AQDLIARILTVDPEQRIKTREILKH 281
A LI +L V+PE+R +I H
Sbjct: 299 ASMLIRNMLRVNPERRATIFDIASH 323
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 197 bits (502), Expect = 6e-50
Identities = 116/315 (36%), Positives = 178/315 (55%), Gaps = 24/315 (7%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G +++G LG G+ KV +A N G+ A+K+I K G L I
Sbjct: 25 LGKYEMGRLLGHGTFAKVYLARNAQSGESVAIKVIDKEKVLKSG-----------LIAHI 73
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
+REI I++ + HPN+++L++V T +Y V+EYV+ GELFN V +G L E A ++F+
Sbjct: 74 KREISILRRVRHPNIVQLFEVMATKSKIYFVMEYVKGGELFNK-VAKGRLKEEMARKYFQ 132
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALES---KDKLLETSCGSPH 190
Q+I +S+CH G+ HRDLKPENLLLD N+K++DFG++A+ +D L T CG+P
Sbjct: 133 QLISAVSFCHFRGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPA 192
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
Y APE+++ Y G + D+WSCGVIL+ L+ G LPF D N+ + K+ G F P
Sbjct: 193 YVAPEVLARKGYDGAKVDIWSCGVILFVLMAGFLPF--HDRNVMAMYKKIYRGDFRCPRW 250
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK-YPSIK----DSKSIRNLPREDTY 305
+ E L+ R+L PE+R +I++ +K + IK D + N+ +D
Sbjct: 251 FPV--EINRLLIRMLETKPERRFTMPDIMETSWFKKGFKHIKFYVEDDHQLCNVADDDEI 308
Query: 306 LNPLSLEGGNQCVDE 320
+ S+ G + V E
Sbjct: 309 ESIESVSGRSSTVSE 323
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 197 bits (502), Expect = 6e-50
Identities = 110/288 (38%), Positives = 172/288 (59%), Gaps = 19/288 (6%)
Query: 2 NGNGITTLKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMI 61
NG+ + G G ++LG LG G+ KV A N G+ A+K++ K + +
Sbjct: 9 NGSDGGSSTGLLHGRYELGRLLGHGTFAKVYHARNIQTGKSVAMKVVGK-----EKVVKV 63
Query: 62 GGNDPDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERG 121
G D I+REI +M+++ HPN++ L++V + +Y +E V GELF V +G
Sbjct: 64 GMVDQ------IKREISVMRMVKHPNIVELHEVMASKSKIYFAMELVRGGELF-AKVAKG 116
Query: 122 PLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALE---SK 178
L E+ A +F+Q+I + +CH+ G+ HRDLKPENLLLD + N+K+ DFG++A +
Sbjct: 117 RLREDVARVYFQQLISAVDFCHSRGVYHRDLKPENLLLDEEGNLKVTDFGLSAFTEHLKQ 176
Query: 179 DKLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLL 238
D LL T+CG+P Y APE++ Y G ++D+WSCGVIL+ LL G LPF +D N+ N+
Sbjct: 177 DGLLHTTCGTPAYVAPEVILKKGYDGAKADLWSCGVILFVLLAGYLPF--QDDNLVNMYR 234
Query: 239 KVQSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
K+ G F+ PG +SS+A+ L+ ++L +P RI +++ P +K
Sbjct: 235 KIYRGDFKCPG--WLSSDARRLVTKLLDPNPNTRITIEKVMDSPWFKK 280
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 197 bits (501), Expect = 8e-50
Identities = 112/286 (39%), Positives = 171/286 (59%), Gaps = 19/286 (6%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G ++LG LG GS KV +A + + G+ A+KII K T+ G +P ++
Sbjct: 18 LGKYELGRRLGSGSFAKVHVARSISTGELVAIKIIDKQ------KTIDSGMEPRII---- 67
Query: 74 EREIIIMKLL-NHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
REI M+ L NHPNVL++++V T +Y+V+EY GELF L+ G L E+ A R+F
Sbjct: 68 -REIEAMRRLHNHPNVLKIHEVMATKSKIYLVVEYAAGGELFTKLIRFGRLNESAARRYF 126
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAAL---ESKDKLLETSCGSP 189
+Q+ +S+CH GI HRD+KP+NLLLD + N+K++DFG++AL S + LL T+CG+P
Sbjct: 127 QQLASALSFCHRDGIAHRDVKPQNLLLDKQGNLKVSDFGLSALPEHRSNNGLLHTACGTP 186
Query: 190 HYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPG 249
Y APE+++ Y G ++D WSCGV L+ LL G +PFD D NI + K+ + P
Sbjct: 187 AYTAPEVIAQRGYDGAKADAWSCGVFLFVLLAGYVPFD--DANIVAMYRKIHKRDYRFP- 243
Query: 250 DDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKS 295
IS A+ +I ++L +PE R+ ++ +K I + +S
Sbjct: 244 -SWISKPARSIIYKLLDPNPETRMSIEAVMGTVWFQKSLEISEFQS 288
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 197 bits (500), Expect = 1e-49
Identities = 159/532 (29%), Positives = 250/532 (46%), Gaps = 65/532 (12%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
IG ++L T+G G+ KV +A + G++ A+KII K+ N +
Sbjct: 53 IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF----------- 101
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
RE+ IMK+LNHPN+++L++V ET K LY+++EY GE+F+ LV G + E EA FR
Sbjct: 102 -REVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGKMKEKEARSKFR 160
Query: 134 Q-----------------------IIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADF 170
Q I+ + YCH IVHRDLK ENLLLD N+K+ADF
Sbjct: 161 QGCQAGQTIKVQVSFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADF 220
Query: 171 GMAALESKDKLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEED 230
G + + L+T CGSP YAAPE+ G Y G E DVWS GVILY L++G LPFD +
Sbjct: 221 GFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQ- 279
Query: 231 GNIRNLLLKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSI 290
N++ L +V GK+ +P +S++ ++L+ R L ++P +R +I+K +
Sbjct: 280 -NLKELRERVLRGKYRIP--FYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWI------ 330
Query: 291 KDSKSIRNLPREDTYLNPLSLEGGNQCVDETILQNLVVLWHGRNKEDIITKLMEPGANLE 350
N E+ L P +E D+ + +V + G ++E+I L + +
Sbjct: 331 -------NAGHEEDELKPF-VEPELDISDQKRIDIMVGM--GYSQEEIQESLSKMKYDEI 380
Query: 351 KTFYALLHRFKHDNYXXXXXXXXXXXXXSVSSNSLMYVGSLPSP-NKSDSPVTTPKKKRT 409
Y LL R + V +S + + SP +K V++ +K+R
Sbjct: 381 TATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRR 440
Query: 410 SIIVASSSHKRPVSMQKLSSQHSSP---VKNGSIGKRLSKTFPSNKRI---SQLVSNSSS 463
A + V+ K S ++ ++G ++ S + K I S ++ N+S+
Sbjct: 441 YSDHAGPAIPSVVAYPKRSQTSTADGDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASN 500
Query: 464 PTPA---AHKRVSRINDSAAPPVPKEMLRDYKRQSKRQSKRFSLLPNMKRGS 512
P A K+ S + S Y + + R S++ N K S
Sbjct: 501 PNKADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENS 552
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 197 bits (500), Expect = 1e-49
Identities = 125/351 (35%), Positives = 192/351 (54%), Gaps = 39/351 (11%)
Query: 15 GPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIE 74
G + + LG G GKV +A + Q+ A+KII K +G + P V +
Sbjct: 9 GFYAVHDELGSGGFGKVRLATHLLTNQKVAIKIIDKK--------QLGHDLPRV-----Q 55
Query: 75 REIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQ 134
E+ ++ L+H N+ RLY ET ++V+EY GE+F+ +V + L E+EA FFRQ
Sbjct: 56 TEMDALRNLSHQNICRLYHYIETEDKFFIVMEYCSGGEMFDYIVRKERLEESEARHFFRQ 115
Query: 135 IIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKL----LETSCGSPH 190
++ I++ H+ G HRDLKPENLLL ++KL DFG+ A K ++ L+T CGSP
Sbjct: 116 LVSAIAFVHSQGYAHRDLKPENLLLTEDLHLKLIDFGLCAKTEKGRIDKHNLDTCCGSPA 175
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
YAAPE++ GL Y G E+DVWS G++LY LL G LPF ED N++ + K+QSG F P
Sbjct: 176 YAAPELIQGLQYKGNEADVWSMGILLYTLLVGALPF--EDDNMQIMYKKIQSGCFYEP-- 231
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLL-RKYPSIKDSKSIRNLPREDTYLNPL 309
+ +S ++ L+ +L V PE+RI +++L+H L KY +I +
Sbjct: 232 EFLSPLSKQLLRAMLQVVPERRISVKKLLEHDWLNHKYTQPVKWNTIYD----------- 280
Query: 310 SLEGGNQCVDETILQNLVVLWHGRNKEDIITKLMEPGAN-LEKTFYALLHR 359
+D + + + + + + +I K+ E + + T+YALLHR
Sbjct: 281 -----KNFIDRDVARVMSKYYGFESTDKMIEKIKEWNFDYMTSTYYALLHR 326
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 197 bits (500), Expect = 1e-49
Identities = 107/276 (38%), Positives = 167/276 (59%), Gaps = 19/276 (6%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G +++G LG G+ KV +A N + A+K+I K + GG L I
Sbjct: 23 LGRYEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDKE------KVLKGG-----LIAHI 71
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
+REI I++ + HPN+++L++V T +Y V+EYV GELFN V +G L E A ++F+
Sbjct: 72 KREISILRRVRHPNIVQLFEVMATKAKIYFVMEYVRGGELFNK-VAKGRLKEEVARKYFQ 130
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALES---KDKLLETSCGSPH 190
Q+I +++CHA G+ HRDLKPENLLLD N+K++DFG++A+ +D L T CG+P
Sbjct: 131 QLISAVTFCHARGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPA 190
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
Y APE+++ Y + D+WSCGVIL+ L+ G LPF D N+ + K+ G+F P
Sbjct: 191 YVAPEVLARKGYDAAKVDIWSCGVILFVLMAGYLPF--HDRNVMAMYKKIYRGEFRCP-- 246
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
S+E L++++L +PE+R EI+++ +K
Sbjct: 247 RWFSTELTRLLSKLLETNPEKRFTFPEIMENSWFKK 282
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 196 bits (499), Expect = 1e-49
Identities = 107/259 (41%), Positives = 149/259 (57%), Gaps = 16/259 (6%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G+ GKV + N+ GQ+ A+K I K A+ + I RE+ IM
Sbjct: 88 LGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLV-----------RIRREVQIMSS 136
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
++HPN++ +Y+V+E + + +V+E+ GEL++ L ER L E EA R FRQ+ + YC
Sbjct: 137 VHHPNIIHIYEVFENREKMVLVMEFAAGGELYDYLSERKVLTEEEARRIFRQVATAVYYC 196
Query: 143 HALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEIVSGLPY 202
H I HRDLK EN+LLD K N K+ADFG++ + +LL T CGSP YA+PEIV G PY
Sbjct: 197 HKHKICHRDLKLENILLDEKGNAKIADFGLSNVFDDQRLLGTFCGSPLYASPEIVEGTPY 256
Query: 203 HGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISSEAQDLIA 262
G E D WS GV+LY L+ G +PFD N + L+ ++ G + P S A LI
Sbjct: 257 QGPEVDCWSLGVLLYTLVYGSMPFD--GSNFKRLVKQISQGDYYEP---RKPSRASTLIR 311
Query: 263 RILTVDPEQRIKTREILKH 281
+LTV P +R +I H
Sbjct: 312 DMLTVCPRKRASIEQICSH 330
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 195 bits (496), Expect = 3e-49
Identities = 121/319 (37%), Positives = 183/319 (56%), Gaps = 26/319 (8%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
++L T+G G KV +A + G+ A+KI+ K+ G+D LP I+ E
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTL---------GSD---LPR-IKTE 57
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I +K L H ++ +LY V ET+ ++MVLEY GELF+ ++ + L E E FRQI+
Sbjct: 58 IEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIV 117
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALE--SKDKLLETSCGSPHYAAP 194
++Y H+ G HRDLKPENLL D +KL DFG+ A +KD L+T CGS YAAP
Sbjct: 118 SAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAP 177
Query: 195 EIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEIS 254
E++ G Y G E+DVWS G++LY L+ G LPFD D N+ L K+ GK+++P +S
Sbjct: 178 ELIQGKSYLGSEADVWSMGILLYVLMCGFLPFD--DDNVMALYKKIMRGKYDVP--KWLS 233
Query: 255 SEAQDLIARILTVDPEQRIKTREILKHPLLRK---YPSIKDSKSIRNLPREDTYLNPLSL 311
+ L+ ++L VDP++RI + +L HP + + YP SK+ + +D + LS+
Sbjct: 234 PSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKN-PFIHLDDDCVTELSV 292
Query: 312 EGGNQCVDETILQNLVVLW 330
N + +++L+ LW
Sbjct: 293 HHRN---NRQTMEDLISLW 308
>SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase
Length = 532
Score = 195 bits (495), Expect = 4e-49
Identities = 109/269 (40%), Positives = 156/269 (57%), Gaps = 16/269 (5%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+GPW LG TLG G+ KV + K Q K+ K ++N + D D +
Sbjct: 20 VGPWLLGRTLGQGNLAKVKLG----KHFQTNEKVALKMVYNDELE------DKDTWKR-L 68
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
+RE+ I++ L+HPN++ LY V+ K + LEY++ +L +++V+ L E + FR
Sbjct: 69 QREVTILRQLHHPNIITLYQVFRVPKYTVLALEYMDT-DLHSMVVKHNRLDECTTRKIFR 127
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QI+ I YCH + HRDLK EN+LL+ VKL DFG++ L TSCG+PHYAA
Sbjct: 128 QIVHAIDYCHLHRVAHRDLKLENILLNKDLVVKLTDFGLSNFMLDGSFLSTSCGTPHYAA 187
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE++ G Y G + DVW CG++LY +L G PF ED I N+L +V G + +P +
Sbjct: 188 PEVIQGRYYDGCDVDVWGCGILLYLMLVGEFPF--EDVTISNVLSRVCKGIYTIP--SFV 243
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHP 282
SS A DLI ++L V P RIK EI++HP
Sbjct: 244 SSSASDLIRQMLMVLPTSRIKVAEIMQHP 272
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 194 bits (493), Expect = 6e-49
Identities = 109/260 (41%), Positives = 155/260 (58%), Gaps = 17/260 (6%)
Query: 22 TLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMK 81
TLG G+ GKV A E+ G+ A+K I K + M I REI IM
Sbjct: 58 TLGKGTYGKVKKA-RESSGRLVAIKSIRKDKIKDEQDLM-----------HIRREIEIMS 105
Query: 82 LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISY 141
LNHP+++ +++V+E S + +V+EY +G+L++ + ER L E EA FFRQI+ + Y
Sbjct: 106 SLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHY 165
Query: 142 CHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEIVSGLP 201
CH +VHRDLK EN+LLD N+K+ADFG++ L + K L+T CGSP YA+PEIV+G P
Sbjct: 166 CHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKP 225
Query: 202 YHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISSEAQDLI 261
Y G E D WS GV+LY L+ G +PFD D I L+ ++ +G + P S+A LI
Sbjct: 226 YTGPEVDSWSLGVLLYILVHGTMPFDGHDHKI--LVKQISNGAYREPPK---PSDACGLI 280
Query: 262 ARILTVDPEQRIKTREILKH 281
+L V+P +R ++ H
Sbjct: 281 RWLLMVNPTRRATLEDVASH 300
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 192 bits (489), Expect = 2e-48
Identities = 110/289 (38%), Positives = 175/289 (60%), Gaps = 20/289 (6%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G ++LG LG GS KV +A + + AVKII K T+ G +P ++
Sbjct: 22 LGKYELGRRLGSGSFAKVHLARSIESDELVAVKIIEKK------KTIESGMEPRII---- 71
Query: 74 EREIIIMKLL-NHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
REI M+ L +HPN+L++++V T +Y+V+E GELF+ ++ RG LPE+ A R+F
Sbjct: 72 -REIDAMRRLRHHPNILKIHEVMATKSKIYLVMELASGGELFSKVLRRGRLPESTARRYF 130
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALES--KDKLLETSCGSPH 190
+Q+ + + H G+ HRD+KP+NLLLD + N+K++DFG++AL ++ LL T+CG+P
Sbjct: 131 QQLASALRFSHQDGVAHRDVKPQNLLLDEQGNLKVSDFGLSALPEHLQNGLLHTACGTPA 190
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
Y APE++S Y G ++D WSCGVIL+ LL G +PFD D NI + K+ + P
Sbjct: 191 YTAPEVISRRGYDGAKADAWSCGVILFVLLVGDVPFD--DSNIAAMYRKIHRRDYRFP-- 246
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNL 299
IS +A+ +I ++L +P R+ ++K +K S++ S+ RN+
Sbjct: 247 SWISKQAKSIIYQMLDPNPVTRMSIETVMKTNWFKK--SLETSEFHRNV 293
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 192 bits (489), Expect = 2e-48
Identities = 114/284 (40%), Positives = 163/284 (57%), Gaps = 26/284 (9%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G + + T+G G+ V +A + + A+KII KS + +
Sbjct: 138 VGFYDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNLQKV------------ 185
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
RE+ IMK L HP++++LY V ET +Y+V EY +GE+F+ + + G + E+ A F
Sbjct: 186 YREVEIMKRLKHPHIIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFW 245
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QII + YCH GIVHRDLK ENLLLD N+K+ADFG + +LL T CGSP YAA
Sbjct: 246 QIISAVEYCHKKGIVHRDLKAENLLLDLNMNIKIADFGFSNHFKPGELLATWCGSPPYAA 305
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+ G Y G E D+WS GV+LY L+ G LPFD +++L +V SG+F +P +
Sbjct: 306 PEVFEGKQYTGPEIDIWSLGVVLYVLVCGALPFD--GSTLQSLRDRVLSGRFRIP--FFM 361
Query: 254 SSEAQDLIARILTVDPEQR-----IKTR-----EILKHPLLRKY 287
SSE + LI R+L ++P +R IK E+L+H L+ KY
Sbjct: 362 SSECEHLIRRMLVLEPTRRYTIDQIKRHRWMCPELLEHVLIAKY 405
>ECU03g0980 [T] KOG0583 Serine/threonine protein kinase
Length = 566
Score = 192 bits (488), Expect = 2e-48
Identities = 109/306 (35%), Positives = 172/306 (55%), Gaps = 13/306 (4%)
Query: 9 LKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDV 68
++G IG ++ LG GS+ KVV+ + G++ A+KII + + + M D V
Sbjct: 50 IEGKWIGSYRFVKQLGTGSSSKVVLGRDVRSGEKVAIKIIPRRVNGGETGDMEMRCDQRV 109
Query: 69 LPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEA 128
RE+II +LNHP++ RL + + +++ EYV+ +L+++++ GPL E E
Sbjct: 110 F-----REVIISSVLNHPHIARLKNFLYSPTHYFLIFEYVKGRQLYDIIISSGPLKEKEG 164
Query: 129 VRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGS 188
R+FRQ++ I Y H +VHRDLK EN+L+D NVKL DFG++ LL T CGS
Sbjct: 165 QRYFRQLLSAIDYIHRNSVVHRDLKIENILIDENDNVKLIDFGLSNFYDNKTLLNTFCGS 224
Query: 189 PHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMP 248
++AAPE++ G Y G E DVWS GV+LYA+L G +PFD+ED ++ L K+ F+
Sbjct: 225 LYFAAPELLQGQRYCGPEIDVWSLGVVLYAILCGCVPFDDED--VQGLQAKIMDADFKF- 281
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK-YPSIKDSKSIRNLP---REDT 304
IS EA +LI ++ P R+ +++ + K S +S + + P +
Sbjct: 282 -CKTISREAMELIRGMIVAQPSSRMGLSQVIGSEWVNKGQKSRINSYAAKRYPIMKLNEK 340
Query: 305 YLNPLS 310
Y+ P+S
Sbjct: 341 YIRPIS 346
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 192 bits (488), Expect = 2e-48
Identities = 108/266 (40%), Positives = 158/266 (58%), Gaps = 16/266 (6%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
IG +++G T+G G+ KV + Y+ T G AVKII K++ +G L +
Sbjct: 9 IGKYEIGRTIGEGNFAKVKLGYDTTNGTYVAVKIIDKALVIQKG-----------LESQV 57
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
+REI MKLLNHPN++++++V T + +V+EYV G+L + L R + E++A + F+
Sbjct: 58 KREIRTMKLLNHPNIVQIHEVIGTKTKICIVMEYVSGGQLSDRL-GRQKMKESDARKLFQ 116
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
Q+I + YCH G+ HRDLKP+NLLLD K N+K++DFG++A+ +L T+CGSP Y A
Sbjct: 117 QLIDAVDYCHNRGVYHRDLKPQNLLLDSKGNLKVSDFGLSAVPKSGDMLSTACGSPCYIA 176
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE++ Y G DVWSCGVIL+ LL G PFD D + L K+ + P
Sbjct: 177 PELIMNKGYSGAAVDVWSCGVILFELLAGYPPFD--DHTLPVLYKKILRADYTFP--PGF 232
Query: 254 SSEAQDLIARILTVDPEQRIKTREIL 279
+ E + LI IL +P RI EI+
Sbjct: 233 TGEQKRLIFNILDPNPLSRITLAEII 258
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 191 bits (486), Expect = 4e-48
Identities = 112/306 (36%), Positives = 171/306 (55%), Gaps = 24/306 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+++G LG G+ KV + + A+K+I K G L I+RE
Sbjct: 12 YEVGRLLGQGTFAKVYFGRSNHTNESVAIKMIDKDKVMRVG-----------LSQQIKRE 60
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I +M++ HPNV+ LY+V T +Y V+EY + GELFN V +G L E+ A ++F Q+I
Sbjct: 61 ISVMRIAKHPNVVELYEVMATKSRIYFVIEYCKGGELFNK-VAKGKLKEDVAWKYFYQLI 119
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAAL---ESKDKLLETSCGSPHYAA 193
+ +CH+ G+ HRD+KPENLLLD N+K++DFG++AL + +D LL T+CG+P Y A
Sbjct: 120 SAVDFCHSRGVYHRDIKPENLLLDDNDNLKVSDFGLSALADCKRQDGLLHTTCGTPAYVA 179
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+++ Y G ++D+WSCGV+L+ LL G LPF D N+ + K+ F+ P
Sbjct: 180 PEVINRKGYEGTKADIWSCGVVLFVLLAGYLPF--HDTNLMEMYRKIGKADFKCP--SWF 235
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKD---SKSIRNLPREDTYLNPLS 310
+ E + L+ ++L + E RI +I + RK +K K + RE T NP+
Sbjct: 236 APEVKRLLCKMLDPNHETRITIAKIKESSWFRKGLHLKQKKMEKMEKQQVREAT--NPME 293
Query: 311 LEGGNQ 316
G Q
Sbjct: 294 AGGSGQ 299
>SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase
Length = 891
Score = 190 bits (483), Expect = 9e-48
Identities = 106/282 (37%), Positives = 164/282 (57%), Gaps = 12/282 (4%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISK---SIFNAQGSTMIGGNDPDVLP 70
IG + LG T+G GS GKV +A++ G+Q A+KI+++ I A+ +
Sbjct: 122 IGNYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSE 181
Query: 71 YGIE----REIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPEN 126
E RE + LL HP + DV+ T+ YMV E+V+ G++ + ++ G L E
Sbjct: 182 KNKEIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEK 241
Query: 127 EAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSC 186
+A +F RQI +SY H +VHRDLK EN+L+ ++K+ DFG++ L + L T C
Sbjct: 242 QARKFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNLYRRQSRLRTFC 301
Query: 187 GSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFE 246
GS ++AAPE+++ PY G E DVWS G++LY L+ G++PFD D N+ L K++ G E
Sbjct: 302 GSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPFD--DQNMSALHAKIKKGTVE 359
Query: 247 MPGDDEISSEAQDLIARILTVDPEQRIKTREILKHP-LLRKY 287
P +SS+ + L++R+L DP +R E+L HP ++R Y
Sbjct: 360 YP--SYLSSDCKGLLSRMLVTDPLKRATLEEVLNHPWMIRNY 399
>Hs14042947 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 189 bits (479), Expect = 3e-47
Identities = 112/286 (39%), Positives = 162/286 (56%), Gaps = 23/286 (8%)
Query: 19 LGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREII 78
LG LG GS KV AY+E A+KII + A D L + REI
Sbjct: 14 LGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPA-----------DFLEKFLPREIE 62
Query: 79 IMKLLNHPNVLRLYDVWETSKD-LYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIII 137
I+ +LNH ++++ Y+++ETS +Y+V+E +G+L L+ RG L E+EA + F Q+ +
Sbjct: 63 ILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSL 122
Query: 138 GISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKD-----KLLETSCGSPHYA 192
I YCH L +VHRDLK +NLLLD FN+KL+DF + +D L +T CGSP YA
Sbjct: 123 AIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYA 182
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDE 252
APE++ G+PY D+WS GVILY ++ G +P+D D NI+ +L + + P
Sbjct: 183 APEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYD--DSNIKKMLRIQKEHRVNFPRSKH 240
Query: 253 ISSEAQDLIARILTVDPEQRIKTREILKH----PLLRKYPSIKDSK 294
++ E +DLI +L D +R+ EIL H P R PS+ +K
Sbjct: 241 LTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINK 286
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 188 bits (477), Expect = 5e-47
Identities = 106/277 (38%), Positives = 161/277 (57%), Gaps = 21/277 (7%)
Query: 10 KGDTIGPWKLGSTLGVGSTGKVVMAYN-ETKGQQAAVKIISKSIFNAQGSTMIGGNDPDV 68
K G + LG LG G+ KV A + + G+ A+K++ K D
Sbjct: 21 KSALFGKYDLGKLLGSGAFAKVYQAEDLQNGGESVAIKVVQKKRLK------------DG 68
Query: 69 LPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEA 128
L ++REI +M+ L HP+++ L +V T +Y V+E + GELF+ V E+ +
Sbjct: 69 LTAHVKREISVMRRLRHPHIVLLSEVLATKTKIYFVMELAKGGELFSR-VTSNRFTESLS 127
Query: 129 VRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESK---DKLLETS 185
++FRQ+I + YCHA G+ HRDLKPENLLLD ++K++DFG++A++ + D +L T
Sbjct: 128 RKYFRQLISAVRYCHARGVFHRDLKPENLLLDENRDLKVSDFGLSAMKEQIHPDGMLHTL 187
Query: 186 CGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKF 245
CG+P Y APE++ Y G ++D+WSCGV+L+ L G LPF D NI L K+ ++
Sbjct: 188 CGTPAYVAPELLLKKGYDGSKADIWSCGVVLFLLNAGYLPF--RDPNIMGLYRKIHKAQY 245
Query: 246 EMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHP 282
++P D SS+ + L+ R+L +PE RI EILK P
Sbjct: 246 KLP--DWTSSDLRKLLRRLLEPNPELRITVEEILKDP 280
>YPL141c [T] KOG0583 Serine/threonine protein kinase
Length = 865
Score = 187 bits (475), Expect = 8e-47
Identities = 116/295 (39%), Positives = 170/295 (57%), Gaps = 31/295 (10%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKG----------QQAAVKIISK-SIFNAQGSTMI 61
T GP+ LGSTLG G GKV + + + +Q A+K+I + SI N +
Sbjct: 37 TFGPYILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEV- 95
Query: 62 GGNDPDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERG 121
I REI +K L+HPN+++L +V + S+ + +VLEY GE + + ++
Sbjct: 96 ----------KIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKR 145
Query: 122 PLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMA-ALESKDK 180
L E A R F Q+I G+ Y H+ G+VHRDLK ENLLLD N+ + DFG S+++
Sbjct: 146 RLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNE 205
Query: 181 LLETSCGSPHYAAPE-IVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGN-----IR 234
L++TSCGSP YAAPE ++S PY ++D+WSCGVILYA+L G LP+D++ N I
Sbjct: 206 LMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIG 265
Query: 235 NLLLKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPS 289
L + S + P D I +DL+ R+L DP++RI ++I KH L+ + S
Sbjct: 266 RLYNYINSTPLKFP--DYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWLKPHSS 318
>SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase
Length = 423
Score = 187 bits (475), Expect = 8e-47
Identities = 110/277 (39%), Positives = 157/277 (55%), Gaps = 17/277 (6%)
Query: 11 GDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLP 70
G +G W + T+G GS GKV + N G++AA+K+I + N + +
Sbjct: 47 GRQVGNWIIKKTIGAGSMGKVKLVVNILTGEKAALKMIPFTPNNTSQTVRV--------- 97
Query: 71 YGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVR 130
+RE ++ +LL HPN+ R+ D T Y++ EYV G+L ++ RG L E+ A
Sbjct: 98 ---QREALLGRLLRHPNICRVIDCIRTPACTYILFEYVPGGQLLEYILARGKLDEDLARS 154
Query: 131 FFRQIIIGISYCHALGIVHRDLKPENLLLDHKFN-VKLADFGMAALESKDKLLETSCGSP 189
F Q+I + Y H IVHRDLK EN+LL VKL DFG++ SKD LL T CGS
Sbjct: 155 FAMQLINALVYLHKNFIVHRDLKIENVLLTQDSRQVKLIDFGLSNFYSKDDLLRTYCGSL 214
Query: 190 HYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPG 249
++AAPE++ PY G E DVWS GV++Y ++ GR+PFD D ++ L K++SGK E P
Sbjct: 215 YFAAPELLDAKPYIGPEVDVWSLGVVIYVMVCGRVPFD--DVSVPMLHSKIKSGKLEFP- 271
Query: 250 DDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
IS + LIA +L V+P +R + K P L+K
Sbjct: 272 -SYISEDCCSLIAAMLNVNPRKRCSLEQAAKFPWLKK 307
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 186 bits (472), Expect = 2e-46
Identities = 105/281 (37%), Positives = 160/281 (56%), Gaps = 19/281 (6%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ +G LG G+ KV + Q A+K+I K G L I+RE
Sbjct: 12 YDVGRLLGQGTFAKVYYGRSILTNQSVAIKMIDKEKVMKVG-----------LIEQIKRE 60
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I +M++ HPNV+ LY+V T +Y V+EY + GELFN V +G L ++ A ++F Q+I
Sbjct: 61 ISVMRIARHPNVVELYEVMATKTRIYFVMEYCKGGELFNK-VAKGKLRDDVAWKYFYQLI 119
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAAL---ESKDKLLETSCGSPHYAA 193
+ +CH+ + HRD+KPENLLLD N+K++DFG++AL + +D LL T+CG+P Y A
Sbjct: 120 NAVDFCHSREVYHRDIKPENLLLDDNENLKVSDFGLSALADCKRQDGLLHTTCGTPAYVA 179
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+++ Y G ++D+WSCGV+L+ LL G LPF D N+ + K+ F+ P
Sbjct: 180 PEVINRKGYDGTKADIWSCGVVLFVLLAGYLPF--HDSNLMEMYRKIGKADFKAP--SWF 235
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSK 294
+ E + L+ ++L +PE RI I + RK +K K
Sbjct: 236 APEVRRLLCKMLDPNPETRITIARIRESSWFRKGLHMKQKK 276
>CE16081 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 182 bits (463), Expect = 2e-45
Identities = 105/294 (35%), Positives = 165/294 (55%), Gaps = 22/294 (7%)
Query: 11 GDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLP 70
G IG ++LG LG G+ KV + ++ ++ AVKI+ K+ +A+ ++
Sbjct: 43 GRRIGFYRLGKELGAGNFSKVKLGVHQLTKEKVAVKIMDKAKMDAKAQKLLS-------- 94
Query: 71 YGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVR 130
REI M+ +NHPN+++L++V ET +++V+EY GEL+ + ERG L E +A
Sbjct: 95 ----REIQAMEEMNHPNIVKLFEVVETLTRVHLVIEYASGGELYTYVHERGKLTEGDAKP 150
Query: 131 FFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPH 190
F QI+ +S+ H+ IVHRD+K EN++ VKL DFG + L ++++L T CGSP
Sbjct: 151 LFAQIVSAVSHMHSRNIVHRDIKAENVMFSSPNTVKLVDFGFSCLVDREQMLRTFCGSPP 210
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
YAAPE+ Y G DVW+ GV+L+ +L G PF E + ++ + + +GK+++P
Sbjct: 211 YAAPELFQDTSYAGELVDVWALGVLLFFMLIGVTPFKAE--TVPDMKVLITAGKYQIP-- 266
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLR------KYPSIKDSKSIRN 298
D +S A +LI +L D QR + KH +R Y SIK + I N
Sbjct: 267 DYVSLLATELIKSMLKTDTGQRADIDSVKKHFWMRDCRFTKSYLSIKATAKIDN 320
>YDR122w [T] KOG0583 Serine/threonine protein kinase
Length = 1064
Score = 182 bits (462), Expect = 3e-45
Identities = 98/284 (34%), Positives = 166/284 (57%), Gaps = 19/284 (6%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIIS---KSIFNAQGSTMIGGNDPDVL 69
++G W+ T+G GS GKV +A + + AVKI++ K+ + + N+ DVL
Sbjct: 116 SLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVL 175
Query: 70 PYGIE------------REIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLL 117
+ RE + ++L HP++ RL+++ S YM+ EYV G+L + +
Sbjct: 176 ERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYI 235
Query: 118 VERGPLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALES 177
++ G + E++A +F R I + Y HA IVHRDLK EN+++ +K+ DFG++ +
Sbjct: 236 IQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYD 295
Query: 178 KDKLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLL 237
K L T CGS ++AAPE++ PY G E DVWS GV+L+ L+ G++PFD+E+ ++ L
Sbjct: 296 SRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSV--LH 353
Query: 238 LKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKH 281
K++ GK E P +S E L++++L VDP++R +++++H
Sbjct: 354 EKIKQGKVEYP--QHLSIEVISLLSKMLVVDPKRRATLKQVVEH 395
>YLR096w [T] KOG0583 Serine/threonine protein kinase
Length = 1147
Score = 182 bits (461), Expect = 3e-45
Identities = 100/301 (33%), Positives = 169/301 (55%), Gaps = 19/301 (6%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKII---SKSIFNAQGSTMIGGNDPDVL 69
++G W+ T+G GS GKV + + + +KI+ SK+ + Q S N+ ++L
Sbjct: 95 SLGDWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEIL 154
Query: 70 PYG--IEREII----------IMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLL 117
+E+EI + ++L HP++ RL+++ S YM+ EYV G+L + +
Sbjct: 155 ERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYI 214
Query: 118 VERGPLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALES 177
++ G L E+ A +F R I + Y HA IVHRDLK EN+++ +K+ DFG++ +
Sbjct: 215 IQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFD 274
Query: 178 KDKLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLL 237
K L T CGS ++AAPE++ PY G E D+WS G++LY L+ G++PFD+E+ +I L
Sbjct: 275 YRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSI--LH 332
Query: 238 LKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIR 297
K++ GK + P +S E L+ R++ VDP +R + +++HP + + K +
Sbjct: 333 EKIKKGKVDYP--SHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWMNRGYDFKAPSYVP 390
Query: 298 N 298
N
Sbjct: 391 N 391
>YOR233w [T] KOG0583 Serine/threonine protein kinase
Length = 800
Score = 181 bits (459), Expect = 6e-45
Identities = 112/290 (38%), Positives = 162/290 (55%), Gaps = 24/290 (8%)
Query: 10 KGDTIGPWKLGSTLGVGSTGKVVMAYNETKG-----QQAAVKIISKSIFNAQGSTMIGGN 64
K T GP+ +GSTLG G GKV + + + +Q A+K+I + I
Sbjct: 39 KHATFGPYIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIK-- 96
Query: 65 DPDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLP 124
I REI +K L HPN++ L +V + SK + +VLE+V GE + + + L
Sbjct: 97 --------IYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLK 148
Query: 125 ENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKD-KLLE 183
E+ A R F Q+I G++Y H G+VHRDLK ENLLLD N+ + DFG +D +L++
Sbjct: 149 ESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMK 208
Query: 184 TSCGSPHYAAPE-IVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGN-----IRNLL 237
TSCGSP YAAPE +VS Y ++DVWSCGVILYA+L G LP+D++ N I L
Sbjct: 209 TSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLY 268
Query: 238 LKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKY 287
+ + P + I+ +DL+ RIL +P +RI + I +H L+ +
Sbjct: 269 KYITQTPLKFP--EYITPIPRDLLRRILVPNPRRRINLQTIKRHVWLKPH 316
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 181 bits (458), Expect = 7e-45
Identities = 99/265 (37%), Positives = 152/265 (57%), Gaps = 19/265 (7%)
Query: 22 TLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMK 81
TLG G+ +VV+A + G+ AVK I K + S+ IE EI +++
Sbjct: 28 TLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESS-------------IENEIAVLR 74
Query: 82 LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISY 141
+ H N++ L D++E+ LY+V++ V GELF+ +VE+G E +A RQ++ + Y
Sbjct: 75 KIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYY 134
Query: 142 CHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEIVS 198
H +GIVHRDLKPENLL D + + ++DFG++ +E K ++ T+CG+P Y APE+++
Sbjct: 135 LHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLA 194
Query: 199 GLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGDDEISSEA 257
PY D WS GVI Y LL G PF DE D + +LK + +F+ P D+IS A
Sbjct: 195 QKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEY-EFDSPYWDDISDSA 252
Query: 258 QDLIARILTVDPEQRIKTREILKHP 282
+D I ++ DP +R + +HP
Sbjct: 253 KDFIRNLMEKDPNKRYTCEQAARHP 277
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 180 bits (457), Expect = 1e-44
Identities = 98/264 (37%), Positives = 152/264 (57%), Gaps = 19/264 (7%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G+ +V++A ++ + A+K I+K + +M E EI ++
Sbjct: 26 LGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSM-------------ENEIAVLHK 72
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
+ HPN++ L D++E+ LY++++ V GELF+ +VE+G E +A R Q++ + Y
Sbjct: 73 IKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYL 132
Query: 143 HALGIVHRDLKPENLL---LDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEIVSG 199
H LGIVHRDLKPENLL LD + ++DFG++ +E +L T+CG+P Y APE+++
Sbjct: 133 HDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQ 192
Query: 200 LPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGDDEISSEAQ 258
PY D WS GVI Y LL G PF DE D + +LK + +F+ P D+IS A+
Sbjct: 193 KPY-SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEY-EFDSPYWDDISDSAK 250
Query: 259 DLIARILTVDPEQRIKTREILKHP 282
D I ++ DPE+R + L+HP
Sbjct: 251 DFIRHLMEKDPEKRFTCEQALQHP 274
>Hs16418343 [T] KOG0583 Serine/threonine protein kinase
Length = 268
Score = 180 bits (456), Expect = 1e-44
Identities = 102/271 (37%), Positives = 160/271 (58%), Gaps = 18/271 (6%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
++LG T+G G+ KV A+++ ++ A+K+I K G + + + RE
Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKM-----------GGPEEFIQRFLPRE 58
Query: 77 IIIMKLLNHPNVLRLYDVWETSKD-LYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
+ I++ L+H N++++Y++ E++ + +V+E E G++F+ ++ GPLPE+ A FRQ+
Sbjct: 59 LQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQM 118
Query: 136 IIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAAL--ESKDKLLETSCGSPHYAA 193
+ I YCH G+ HRDLK EN LL FN+KL DFG A + +S +L +T CGS YAA
Sbjct: 119 VEAIRYCHGCGVAHRDLKCENALL-QGFNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAA 177
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE++ G+P+ + DVWS GV+LY +L LPFD+ D I +L + Q G P I
Sbjct: 178 PEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTD--IPKMLWQQQKG-VSFPTHLSI 234
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLL 284
S++ QDL+ R+L D R E+ HP L
Sbjct: 235 SADCQDLLKRLLEPDMILRPSIEEVSWHPWL 265
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 180 bits (456), Expect = 1e-44
Identities = 106/345 (30%), Positives = 192/345 (54%), Gaps = 23/345 (6%)
Query: 12 DTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPY 71
+ IG + +G +G G+ V +A ++ + A+K I S + + +
Sbjct: 11 EKIGLYDVGRAIGKGNFATVRIARHKIAKTKVAIKSIDVSALDRENLIKL---------- 60
Query: 72 GIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRF 131
ERE+ I+K+++HP++++ Y++ LY+V EY GEL+ L+E+G + EN A ++
Sbjct: 61 --EREVKIVKVIDHPHIVKSYEIMRVDNMLYIVSEYCSSGELYETLIEKGRVAENVARKW 118
Query: 132 FRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHY 191
F + ++Y H+ GIVHRDLK EN+LL N+K+ DFG + ++ D+LL T CGSP Y
Sbjct: 119 FSETASAVAYLHSQGIVHRDLKAENILLGKNSNIKIIDFGFSNFQTGDQLLNTWCGSPPY 178
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDD 251
AAPE++ G Y G ++D+WS GV+LY L+ G PF + ++ L V SG ++P
Sbjct: 179 AAPELLLGNSYDGMKADIWSMGVLLYILVAGGFPFPSD--SVNKLKRSVLSGLVKIP--Y 234
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPLSL 311
+S E D I ++L ++P +R + +L+H + ++ +++ + L E + + +
Sbjct: 235 WVSVECADFIRKMLVLNPGKRYTIQNVLQHRWMHIRDDVQKNQAAQLL--EAIPSSSIEI 292
Query: 312 EGGNQCVDETILQNLVVLWHGR-NKEDIITKLMEPGANLEKTFYA 355
+ ++ TI+ + + HG+ ++E II ++ G + E +A
Sbjct: 293 RQQSTKLNPTIM--MFMQQHGKWSEEQIIDAVL--GRDFESPIFA 333
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 178 bits (452), Expect = 4e-44
Identities = 111/288 (38%), Positives = 156/288 (53%), Gaps = 18/288 (6%)
Query: 6 ITTLKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGND 65
+ T G+ I +K+G+ LG GS V A + G + A+K+I K G
Sbjct: 1 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQ----- 55
Query: 66 PDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVER-GPLP 124
++ E+ I L HP++L LY+ +E S +Y+VLE GE+ L R P
Sbjct: 56 ------RVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFS 109
Query: 125 ENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAA-LESKDKLLE 183
ENEA F QII G+ Y H+ GI+HRDL NLLL N+K+ADFG+A L+ +
Sbjct: 110 ENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHY 169
Query: 184 TSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSG 243
T CG+P+Y +PEI + HG ESDVWS G + Y LL GR PFD + ++N L KV
Sbjct: 170 TLCGTPNYISPEIAT-RSAHGLESDVWSLGCMFYTLLIGRPPFDTD--TVKNTLNKVVLA 226
Query: 244 KFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIK 291
+EMP +S EA+DLI ++L +P R+ +L HP + + S K
Sbjct: 227 DYEMP--TFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTK 272
>At4g40010 [T] KOG0583 Serine/threonine protein kinase
Length = 350
Score = 178 bits (452), Expect = 4e-44
Identities = 102/272 (37%), Positives = 151/272 (55%), Gaps = 19/272 (6%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G+ G + + G+ AVK I + + + ++REII +
Sbjct: 10 LGSGNFGVAKLVREKANGEFYAVKYIERGL---------------KIDEHVQREIINHRD 54
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L HPN++R +V+ T L +V+EY GELF + G E+E +F+Q+I G+SYC
Sbjct: 55 LKHPNIIRFKEVFVTPTHLAIVMEYAAGGELFERICNAGRFSEDEGRYYFKQLISGVSYC 114
Query: 143 HALGIVHRDLKPENLLLD--HKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEIVSGL 200
HA+ I HRDLK EN LLD ++K+ DFG + +++ G+P Y APE++S
Sbjct: 115 HAMQICHRDLKLENTLLDGSPSSHLKICDFGYSKSSVLHSQPKSTVGTPAYVAPEVLSRK 174
Query: 201 PYHGFESDVWSCGVILYALLTGRLPFD--EEDGNIRNLLLKVQSGKFEMPGDDEISSEAQ 258
Y+G +DVWSCGV LY +L G PF+ E+ NIRN + ++ S + +P ISSE +
Sbjct: 175 EYNGKIADVWSCGVTLYVMLVGAYPFEDPEDPRNIRNTIQRILSVHYTIPDYVRISSECK 234
Query: 259 DLIARILTVDPEQRIKTREILKHPLLRKYPSI 290
L++RI DP++RI EI KHP K P +
Sbjct: 235 HLLSRIFVADPDKRITVPEIEKHPWFLKGPLV 266
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 177 bits (450), Expect = 6e-44
Identities = 111/288 (38%), Positives = 156/288 (53%), Gaps = 18/288 (6%)
Query: 6 ITTLKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGND 65
+ T G+ I +K+G+ LG GS V A + G + A+K+I K G
Sbjct: 1 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQ----- 55
Query: 66 PDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVER-GPLP 124
++ E+ I L HP++L LY+ +E S +Y+VLE GE+ L R P
Sbjct: 56 ------RVKNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFS 109
Query: 125 ENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAA-LESKDKLLE 183
ENEA F QII G+ Y H+ GI+HRDL NLLL N+K+ADFG+A L+ +
Sbjct: 110 ENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHY 169
Query: 184 TSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSG 243
T CG+P+Y +PEI + HG ESDVWS G + Y LL GR PFD + ++N L KV
Sbjct: 170 TLCGTPNYISPEIAT-RSAHGLESDVWSLGCMFYTLLIGRPPFDTD--TVKNTLNKVVLA 226
Query: 244 KFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIK 291
+EMP +S EA+DLI ++L +P R+ +L HP + + S K
Sbjct: 227 DYEMP--TFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTK 272
>Hs16507245 [T] KOG0583 Serine/threonine protein kinase
Length = 358
Score = 177 bits (449), Expect = 8e-44
Identities = 103/273 (37%), Positives = 154/273 (55%), Gaps = 19/273 (6%)
Query: 19 LGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREII 78
+G LG GS KV AY+E AVKII + D + + RE+
Sbjct: 14 VGINLGKGSYAKVKSAYSERLKFNVAVKIIDRK-----------KTPTDFVERFLPREMD 62
Query: 79 IMKLLNHPNVLRLYDVWETSKD-LYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIII 137
I+ +NH ++++ Y+++ETS +Y+++E +G+L + +G L E+ A + FRQ+
Sbjct: 63 ILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSS 122
Query: 138 GISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDK-----LLETSCGSPHYA 192
+ YCH L IVHRDLK ENLLLD FN+KL+DFG + +D L +T CGS YA
Sbjct: 123 AVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYA 182
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDE 252
APE++ +PY D+WS GVILY ++ G +P+D+ D IR +L + + + P
Sbjct: 183 APEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSD--IRKMLRIQKEHRVDFPRSKN 240
Query: 253 ISSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
++ E +DLI R+L D QR+ EIL H L+
Sbjct: 241 LTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQ 273
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 176 bits (445), Expect = 2e-43
Identities = 123/353 (34%), Positives = 187/353 (52%), Gaps = 31/353 (8%)
Query: 11 GDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLP 70
G G + L TLG G V +A + G++ AVK+I K+ + T+ G+
Sbjct: 10 GKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLD----TLATGH------ 59
Query: 71 YGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGP-LPENEAV 129
+ +E+ MKL+ HPN++RLY+V +T LY++LE ++G++F+ +++ L E+
Sbjct: 60 --LFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPK 117
Query: 130 RFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFN-VKLADFGMAALESKDKLLETSCGS 188
++F QI+ ISYCH L +VHRDLKPEN++ K VKL DFG + K L TSCGS
Sbjct: 118 KYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGS 177
Query: 189 PHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMP 248
Y+APEI+ G Y D+WS GVIL+ L+ G+ PF E N L + K+ +P
Sbjct: 178 LAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQE--ANDSETLTMIMDCKYTVP 235
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNP 308
+S E +DLI R+L DP++R EI HP L+ +K N+P +Y N
Sbjct: 236 --SHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQGVDPSPATK--YNIPLV-SYKN- 289
Query: 309 LSLEGGNQCVDETILQNLVVLWHGRNKEDIITKLMEPGA--NLEKTFYALLHR 359
LS E N + +L ++ D I + +E ++ T++ L R
Sbjct: 290 LSEEEHNSIIQRMVLGDIA-------DRDAIVEALETNRYNHITATYFLLAER 335
>7303211 [T] KOG4717 Serine/threonine protein kinase
Length = 860
Score = 175 bits (443), Expect = 4e-43
Identities = 153/499 (30%), Positives = 222/499 (43%), Gaps = 61/499 (12%)
Query: 11 GDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLP 70
G G + L TLG G V +A + G + AVK++ K+ + DV
Sbjct: 14 GKIAGLYDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKLD------------DVSK 61
Query: 71 YGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGP-LPENEAV 129
+ +E+ MKL+ HPNV+RLY+V +T LY+VLE + G+L++ +++ L E A
Sbjct: 62 AHLFQEVRCMKLVQHPNVVRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELAR 121
Query: 130 RFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFN-VKLADFGMAALESKDKLLETSCGS 188
++FRQI+ I+YCH L +VHRDLKPEN++ K VKL DFG + + LET CGS
Sbjct: 122 KYFRQILRAITYCHQLHVVHRDLKPENVVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGS 181
Query: 189 PHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMP 248
Y+APEI+ G Y D+WS GVILY L+ G+ PF E N L + K+ +P
Sbjct: 182 LAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF--EKANDSETLTMIMDCKYTVP 239
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKY--PSIKDSKSIRNLP------ 300
+S++ +DLIA +L DP++R EI L+ P S S LP
Sbjct: 240 --SHVSTDCRDLIASMLVRDPKKRATVEEIASSAWLKPIDEPDSTTSTSEHFLPLVSREQ 297
Query: 301 --REDTYLNPLSLEGGNQCVDETILQNLVVLWHGRNKEDIITK----LMEPGANLEKTFY 354
ED + GN E ILQ L +NK + IT L E +
Sbjct: 298 LGEEDHAFIIQKMINGNIASKEEILQAL-----DKNKYNHITATYFLLAELRLRRRREEL 352
Query: 355 ALLHRFKHDNYXXXXXXXXXXXXXSVSSNSLMYVGSLPSP---NKSDSPVT---TPKKKR 408
A R +D V S V PSP K P++ TP +
Sbjct: 353 AQKQRLLND------------ASMKVGDASRKLVPEKPSPTEAQKGGVPISINVTPAAQF 400
Query: 409 TSIIVASSSHKRPVSMQKLSSQHSSPVKNGSIGKRLSKTFPSNKR------ISQLVSNSS 462
+ R S+ + + S + ++G L T S + S+ + S
Sbjct: 401 ANDGGKPDKRSRKCSIVREEDEEESATECTAVGNELKVTSSSRREAFSDSPFSRSIHERS 460
Query: 463 SPTPAAHKRVSRINDSAAP 481
S P + +I +S P
Sbjct: 461 SSEPGNQTKGEQIANSGVP 479
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 172 bits (437), Expect = 2e-42
Identities = 104/289 (35%), Positives = 162/289 (55%), Gaps = 25/289 (8%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
++ G +G G+ V + Q A+KII KS + ++ E
Sbjct: 284 YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDM-------------VDSE 330
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I+I++ L+HPN+++L++V+ET ++Y++LEYV+ G+LF+ ++E PE +A +
Sbjct: 331 ILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLC 390
Query: 137 IGISYCHALGIVHRDLKPENLLL----DHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
+ + H IVHRDLKPENLL+ D +KLADFG+A + + + T CG+P Y
Sbjct: 391 KALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLA--KHVVRPIFTVCGTPTYV 448
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEM--PGD 250
APEI+S Y G E D+W+ GVILY LL G PF + + L +Q G FE P
Sbjct: 449 APEILSEKGY-GLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYW 507
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLR---KYPSIKDSKSI 296
D IS A+DL++R+L VDP++R ++L+HP + K ++K K +
Sbjct: 508 DNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIETAGKTNTVKRQKQV 556
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 172 bits (436), Expect = 3e-42
Identities = 103/292 (35%), Positives = 164/292 (55%), Gaps = 27/292 (9%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ + + +G GS +VV + Q A+K+I +G + E E
Sbjct: 98 YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKY--REGREVC------------ESE 143
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
+ +++ + H N+++L +V+ET + +YMV+E GELF+ ++ +G E +A R + ++
Sbjct: 144 LRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVL 203
Query: 137 IGISYCHALGIVHRDLKPENLLLDH---KFNVKLADFGMAALESK--DKLLETSCGSPHY 191
G+ Y HALGI HRDLKPENLL H + + DFG+A+ K D L++T+CG+P Y
Sbjct: 204 DGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEY 263
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD- 250
APE++ PY D+W+ GVI Y LL+G +PF ED N L ++ GK+ G+
Sbjct: 264 IAPEVLVRKPYTN-SVDMWALGVIAYILLSGTMPF--EDDNRTRLYRQILRGKYSYSGEP 320
Query: 251 -DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPR 301
+S+ A+D I R+LTVDP R+ + L+HP + S+ S S++NL R
Sbjct: 321 WPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV---VSMAASSSMKNLHR 369
>ECU07g0360 [D] KOG0580 Serine/threonine protein kinase
Length = 272
Score = 171 bits (432), Expect = 8e-42
Identities = 100/277 (36%), Positives = 151/277 (54%), Gaps = 18/277 (6%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIIS-KSIFNAQGSTMIGGNDPDVLPY 71
T+ +++G LG G G+V +A KG A+KII K I + + I
Sbjct: 6 TLDRFEIGRLLGRGKFGQVWLAREREKGFIVALKIIPIKEIQTVETARQI---------- 55
Query: 72 GIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERG-PLPENEAVR 130
REI I L HPN+LR+Y + ++Y++LEY KGE F L +RG E E
Sbjct: 56 --RREIEIHSNLKHPNILRMYGHFHDKDNIYLILEYAGKGEFFKFLSDRGGKFGEKETSL 113
Query: 131 FFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPH 190
+ RQ+++ ++Y ++HRD+KPENLLL +K+ADFG A + DK T CG+
Sbjct: 114 YIRQVMLALTYMKECNVIHRDIKPENLLLGSDNQLKIADFGWAVYNA-DKRRMTFCGTME 172
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
Y APE+V+ H D+W G++ Y L G+ PF+ ++ N+R K+ S K+ +P
Sbjct: 173 YLAPEMVNN-DIHDSGIDLWCLGILTYEFLMGKTPFESKNRNMREAYKKINSLKYTIP-- 229
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKY 287
+ ISS A D I+R+L + P R++ E L HP + K+
Sbjct: 230 ETISSNASDFISRLLVLSPGDRMELTEALNHPFIVKH 266
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 170 bits (431), Expect = 1e-41
Identities = 106/295 (35%), Positives = 169/295 (56%), Gaps = 15/295 (5%)
Query: 19 LGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREII 78
+ TLG G+ G+V +A+ ++ A+KIISK F A GS DP + +E EI
Sbjct: 222 MSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKF-AIGSAREA--DPAL---NVETEIE 275
Query: 79 IMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIG 138
I+K LNHP ++++ + ++ ++D Y+VLE +E GELF+ +V L E +F Q+++
Sbjct: 276 ILKKLNHPCIIKIKNFFD-AEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLA 334
Query: 139 ISYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYAAPE 195
+ Y H GI+HRDLKPEN+LL + +K+ DFG + + + L+ T CG+P Y APE
Sbjct: 335 VQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPE 394
Query: 196 IVSGLPYHGFES--DVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD--D 251
++ + G+ D WS GVIL+ L+G PF E + +L ++ SGK+ +
Sbjct: 395 VLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQV-SLKDQITSGKYNFIPEVWA 453
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYL 306
E+S +A DL+ ++L VDP+ R T E L+HP L+ + + + + E T L
Sbjct: 454 EVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTAL 508
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 169 bits (428), Expect = 2e-41
Identities = 104/296 (35%), Positives = 166/296 (55%), Gaps = 16/296 (5%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFN-AQGSTMIGGNDPDVLPYGIEREIIIMK 81
LG G+ G V + Y+ QQ A+KI+ K++ + A+ ST +DPD + E IMK
Sbjct: 163 LGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNF--SDPD----RVLNEAKIMK 216
Query: 82 LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISY 141
L+HP V+R++D+ + +YMVLE++ G+L N ++ L E+ + +F Q+ + Y
Sbjct: 217 NLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKY 276
Query: 142 CHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPE--I 196
H GI HRDLKP+N+LL D + +K++DFG++ KD ++ T CG+P Y APE I
Sbjct: 277 LHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLI 336
Query: 197 VSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISSE 256
G + + D+WS GV+L+ L+G LPF +E G +K + P +S
Sbjct: 337 TGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQR 396
Query: 257 AQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLP----REDTYLNP 308
A+ LI ++L VDPE+R ++L+ LR P ++ +K + L E+ +L P
Sbjct: 397 AKLLINQMLIVDPERRPSIDDVLQSSWLRDAPMLQKAKRLMKLDGMEIEEENFLEP 452
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 168 bits (426), Expect = 4e-41
Identities = 97/265 (36%), Positives = 150/265 (56%), Gaps = 21/265 (7%)
Query: 23 LGVGSTGKVVMAYNETK-GQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMK 81
LG G+ KV +A +++ GQ AVK I K + ++ E EI +++
Sbjct: 28 LGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKEESL-------------ENEIKVLR 74
Query: 82 LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISY 141
L H N+++L+D ++ + +Y+V+E V GELF+ +V +G E +A RQ++ + +
Sbjct: 75 KLRHNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEAVGF 134
Query: 142 CHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEIVS 198
H G+VHRDLKPENLL D + ++DFG++ E ++ T+CG+P Y APE++
Sbjct: 135 MHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKTEDSG-VMATACGTPGYVAPEVLQ 193
Query: 199 GLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGDDEISSEA 257
PY G DVWS GVI Y LL G PF DE D N+ ++K + +F+ P D+IS A
Sbjct: 194 QKPY-GKAVDVWSIGVIAYILLCGYPPFYDESDANLFAQIIKGEY-EFDAPYWDQISDSA 251
Query: 258 QDLIARILTVDPEQRIKTREILKHP 282
+D I ++ DPE R ++ L HP
Sbjct: 252 KDFITHLMCCDPEARFTCQDALSHP 276
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 168 bits (426), Expect = 4e-41
Identities = 94/282 (33%), Positives = 158/282 (55%), Gaps = 19/282 (6%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYG 72
++ + +G LG G G V ++ + + A+K++ K+ G + +
Sbjct: 40 SLDDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLG-----------VSHQ 88
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAV--R 130
++REI I L HPN+L LY + K ++++L+Y +GELFN+L + NE + R
Sbjct: 89 LKREIEIQYHLRHPNILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIAGR 148
Query: 131 FFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPH 190
F RQ+ + YCH+ G++HRD+KPENLLLD K N+KLADFG + + K T CG+
Sbjct: 149 FVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWSVVADHSK-RHTLCGTMD 207
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
Y APE+VS P H F D+W+ G++L+ +L G PF + G+ L+ +++ K +P
Sbjct: 208 YLAPEMVSNQP-HDFNVDIWAIGILLFEMLVGYAPFANQTGD--KLIARIKECKIYIP-- 262
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKD 292
++ A LI I+ +P++R+ +I+ HP +++ +D
Sbjct: 263 SVVTDGAASLINAIIKKEPQERLPLVDIMAHPWIKEMKQRED 304
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 168 bits (426), Expect = 4e-41
Identities = 102/280 (36%), Positives = 147/280 (52%), Gaps = 15/280 (5%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMK- 81
LG G + V + G++ A KII G T +P + +EI I++
Sbjct: 29 LGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGET-----NPYHMLEATRQEISILRQ 83
Query: 82 LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISY 141
++ HP ++ L DV+E+ +++V E KGELF+ L L E + RQI G+ Y
Sbjct: 84 VMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEY 143
Query: 142 CHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPE-----I 196
HA IVHRDLKPEN+LLD NVK+ DFG A + + L CG+P Y APE +
Sbjct: 144 IHAKSIVHRDLKPENILLDENHNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPETLKCNM 203
Query: 197 VSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGK--FEMPGDDEIS 254
G P + E D+W+CGVI++ LL G PF + +L + GK F P +IS
Sbjct: 204 FEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMV--MLRNIMEGKYSFTSPEWADIS 261
Query: 255 SEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSK 294
+ +DLI + L VDP QRI +E+L+HP + + D +
Sbjct: 262 EDPKDLIRKCLVVDPSQRITVKEVLRHPFFNQMVLMGDRR 301
>Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 476
Score = 168 bits (425), Expect = 5e-41
Identities = 98/267 (36%), Positives = 146/267 (53%), Gaps = 17/267 (6%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
W L TLG G+ G+V +A N + AVKI+ M D P I++E
Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVD----------MKRAVD---CPENIKKE 55
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I I K+LNH NV++ Y Y+ LEY GELF+ + +PE +A RFF Q++
Sbjct: 56 ICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLM 115
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAAL---ESKDKLLETSCGSPHYAA 193
G+ Y H +GI HRD+KPENLLLD + N+K++DFG+A + ++++LL CG+ Y A
Sbjct: 116 AGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVA 175
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE++ +H DVWSCG++L A+L G LP+D+ + + + + P +I
Sbjct: 176 PELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPW-KKI 234
Query: 254 SSEAQDLIARILTVDPEQRIKTREILK 280
S L+ +IL +P RI +I K
Sbjct: 235 DSAPLALLHKILVENPSARITIPDIKK 261
>ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 488
Score = 167 bits (424), Expect = 6e-41
Identities = 104/286 (36%), Positives = 161/286 (55%), Gaps = 18/286 (6%)
Query: 3 GNGITTLKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIG 62
G IT L+ T + L LG G+ + +A E+ G+Q A+K++ ++
Sbjct: 28 GTVITDLEYHT--KYMLKKLLGRGAYAQCYLAEIES-GEQYAMKVVRLKDIKSRK----- 79
Query: 63 GNDPDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGP 122
+ +E EI I L++PNV+++Y + +S+ ++MVLE E+G L LL G
Sbjct: 80 ------VHEKLESEIAIHSKLDNPNVVKMYRSFRSSEYVFMVLELCERGALDALLKRNGK 133
Query: 123 LPENEAVRFFRQIIIGISYCH-ALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKL 181
L E RF +Q + G+ Y H ++ +VHRDLK NL LD KFNVK+ DFG++A+ +
Sbjct: 134 LKERHVARFVKQTVEGLIYLHNSVSVVHRDLKLGNLFLDSKFNVKIGDFGLSAVIKDGEK 193
Query: 182 LETSCGSPHYAAPEIVSG-LPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKV 240
T CG+P+Y APE++ G H FE+D+WS GVI+Y LL G PF ++ N+ ++ +
Sbjct: 194 KVTMCGTPNYIAPEVLFGKASGHSFEADIWSLGVIIYTLLVGVPPFQKK--NVEDIYKMI 251
Query: 241 QSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
+ + P + ++SSEA DLI +IL +P +R IL H L K
Sbjct: 252 KLNNYIFPENCDLSSEAIDLITQILNTNPLERPTLEHILSHKFLSK 297
>Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 489
Score = 166 bits (421), Expect = 1e-40
Identities = 103/272 (37%), Positives = 152/272 (55%), Gaps = 21/272 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
++L LG G+ V GQ+ A KII+ +A+ + ERE
Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKL------------ERE 60
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I +LL HPN++RL+D Y++ + V GELF +V R E +A +QI+
Sbjct: 61 ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL 120
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMA-ALESKDKLLETSCGSPHYA 192
+ +CH +G+VHRDLKPENLLL K VKLADFG+A +E + + G+P Y
Sbjct: 121 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL 180
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD-- 250
+PE++ PY G D+W+CGVILY LL G PF +ED + L ++++G ++ P
Sbjct: 181 SPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQH--RLYQQIKAGAYDFPSPEW 237
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHP 282
D ++ EA+DLI ++LT++P +RI E LKHP
Sbjct: 238 DTVTPEAKDLINKMLTINPSKRITAAEALKHP 269
>7297080 [T] KOG0583 Serine/threonine protein kinase
Length = 329
Score = 166 bits (421), Expect = 1e-40
Identities = 94/252 (37%), Positives = 146/252 (57%), Gaps = 19/252 (7%)
Query: 19 LGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREII 78
LG +G G+ KV + ++E G++ AVKIISK ++ + + REI
Sbjct: 70 LGKVIGTGNYAKVKIGFSEEYGKRVAVKIISKVKAPSEYTQKF-----------LPREIE 118
Query: 79 IMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIG 138
+K L+H N++ Y ETS +Y++++ E G L + + ER L E ++ F+Q++
Sbjct: 119 AVKGLHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDEPQSRTLFKQLVSA 178
Query: 139 ISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDK-----LLETSCGSPHYAA 193
+ Y H+ G+VHRD+K ENLLLD +N+KL DFG A +++ L +T CGS YA+
Sbjct: 179 VEYIHSKGVVHRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILSKTFCGSYAYAS 238
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PEI+ G+ Y F SD+W+CGV+ YA++ GRLP+ DG+ ++LLK + P
Sbjct: 239 PEILKGVAYDPFMSDIWACGVVCYAMVFGRLPY---DGSNVHILLKRINQSLVFPKSPSA 295
Query: 254 SSEAQDLIARIL 265
SSE + +I IL
Sbjct: 296 SSECKHMIMHIL 307
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 166 bits (420), Expect = 2e-40
Identities = 142/465 (30%), Positives = 216/465 (45%), Gaps = 47/465 (10%)
Query: 14 IGPWKLGST-LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYG 72
+G + +GS LG GS KV + G++ A+K+I K A+ T + N
Sbjct: 58 VGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKK--RAKKDTYVTKN-------- 107
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
+ RE I +++ HPN+ +L D+ ET Y+V+E G L + + E+ L E+EA R+
Sbjct: 108 LRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYI 167
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGM---AALESKDKLLETSCGSP 189
RQ+I + + H G+VHRDLK ENLLLD N+KL DFG+ A + T CGSP
Sbjct: 168 RQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSP 227
Query: 190 HYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPG 249
YAAPE+++ Y G + DVWS GV +YA+LTG LPF E ++R L K+ + P
Sbjct: 228 AYAAPELLARKKY-GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMN-PL 285
Query: 250 DDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPL 309
++S+ A + +L DP +R ++ L + L + + K +P TY N +
Sbjct: 286 PTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWLNENYTGK-------VPCNVTYPNRI 338
Query: 310 SLEGGNQCVDETILQNLVVLWHGRNKEDIITKLMEPGANLEKTFYALLHRFKHDNYXXXX 369
SLE + V + + L G D+I ++ A Y LL++ K + Y
Sbjct: 339 SLEDLSPSVVLHMTEKL-----GYKNSDVINTVLSNRACHILAIYFLLNK-KLERY---- 388
Query: 370 XXXXXXXXXSVSSNSLMYVGSLPSPNKSDSPVTTPKKKRTSIIVASSSH----KRPVSMQ 425
S +SL Y L K +P + + + H K+P +
Sbjct: 389 -----LSGKSDIQDSLCYKTRLYQIEKYRAPKESYEASLDTWTRDLEFHAVQDKKPKEQE 443
Query: 426 KLSSQHSSPVKNGSIGKRLSKTFPSNKRISQLVSNSSSPTPAAHK 470
K P K+L K PS+K+ S + T A K
Sbjct: 444 KRGDFLHRP-----FSKKLDKNLPSHKQPSGSLMTQIQNTKALLK 483
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 164 bits (416), Expect = 5e-40
Identities = 92/269 (34%), Positives = 147/269 (54%), Gaps = 17/269 (6%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYG 72
TI +++G LG G G V +A +T A+K++ KS +I G + +
Sbjct: 26 TINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKS-------QLISGG----VEHQ 74
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
+EREI I LNHPN+++LY + +K +Y+VLEY GE++ L E A ++
Sbjct: 75 LEREIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPTAAKYM 134
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
+I +SYCH ++HRD+KPENLL+ + +K+ DFG + +K +T CG+ Y
Sbjct: 135 YEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSNK-RQTMCGTMDYL 193
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDE 252
PE+V+G H D+W+ GV+ Y L G+ PF+ ED + +++ +F P D
Sbjct: 194 PPEMVNGAD-HSDAVDLWAIGVLCYEFLVGKPPFEHEDQS--KTYAAIKAARFTYP--DS 248
Query: 253 ISSEAQDLIARILTVDPEQRIKTREILKH 281
+ A+DLI R+L VDP+ R ++ +H
Sbjct: 249 VKKGARDLIGRLLVVDPKARCTLEQVKEH 277
>YPL150w [T] KOG0583 Serine/threonine protein kinase
Length = 901
Score = 164 bits (414), Expect = 9e-40
Identities = 143/524 (27%), Positives = 236/524 (44%), Gaps = 61/524 (11%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G +K+ +G GS GKV +A + ++ +K K NDP+++
Sbjct: 38 VGNYKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDK-------------NDPNIV---- 80
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
RE+ + + P + +LY+V T ++M LEY EL++ L+ + E F
Sbjct: 81 -REVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFA 139
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
QI + Y H++ VHRDLK EN+LLD N KL DFG LET CG+ Y A
Sbjct: 140 QISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMA 199
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE++ Y GF+ D+WS GVILY L+TG LPFD++D + + K++ I
Sbjct: 200 PELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDA---KVI 256
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPR------------ 301
+A+DLI+R+L +P +R ++L+HP L+ Y S+ ++ + L R
Sbjct: 257 PDDARDLISRLLAKNPGERPSLSQVLRHPFLQPYGSVVLDQTQKILCRQRSGGTQFKSKL 316
Query: 302 EDTYLNPLSLEG-GNQCVDETILQN---------LVVLWHGRNKEDI-ITKLMEPGANLE 350
E L L G Q + ++IL+ L++L G+ +E+ K +++
Sbjct: 317 ERRLLKRLKQSGVDTQAIKQSILKKKCDSLSGLWLLLLAQGKKQENCKYPKRSRSVLSVK 376
Query: 351 KTFYALLHRFKHDNYXXXXXXXXXXXXXSVSSNSLMYVGSLPSPNKSDSPVTTPKKKRTS 410
K + H + + S + ++ GS S +PV+ K K ++
Sbjct: 377 KVIESATHN-DTNGISEDVLKPSLELSRAASLSKMLNKGS--DFVTSMTPVSRKKSKDSA 433
Query: 411 IIVASSSHKRPVSMQKLSSQH--SSPVKNGSIGKRLSKTFPSNKRISQLVSNSSSPTPAA 468
++ + K +S Q+ S SP K+ + +++S F S K S++S+ +
Sbjct: 434 KVLNPTLSK--ISSQRAYSHSIAGSPRKSNNFLQKVSSFFKSKK------SSNSNSNNSI 485
Query: 469 HKRVSR--INDSAAPPVPKEMLRDYKRQSKRQSKRFSLLPNMKR 510
H VS I + P L+ K Q R + N R
Sbjct: 486 HTNVSESLIASNRGAPSSGSFLK--KNSGSIQKSRTDTVANPSR 527
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 163 bits (412), Expect = 2e-39
Identities = 101/278 (36%), Positives = 149/278 (53%), Gaps = 18/278 (6%)
Query: 11 GDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLP 70
G+TI +++ LG G V A Q A+K+I K + G T
Sbjct: 8 GETIEDYEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTN---------- 57
Query: 71 YGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERG-PLPENEAV 129
+ +E+ I L HP+VL+LY ++ + +Y+VLE GEL + P E EA
Sbjct: 58 -RVRQEVEIHSRLKHPSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTETEAA 116
Query: 130 RFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAA-LESKDKLLETSCGS 188
+Q++ G+ Y H+ I+HRD+ NLLL + +VK+ADFG+A L+ D+ T CG+
Sbjct: 117 SILKQVVAGLLYLHSHNIMHRDISLSNLLLSREMHVKIADFGLATQLKRPDERHMTMCGT 176
Query: 189 PHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMP 248
P+Y +PE+VS HG +DVWS G +LY LL GR PF E +++ L KV ++ MP
Sbjct: 177 PNYISPEVVSRTS-HGLPADVWSVGCMLYTLLVGRPPF--ETDAVQSTLNKVVMSEYIMP 233
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
+S EAQDLI ++L P +RI +L HP + K
Sbjct: 234 A--HLSYEAQDLINKLLKKLPHERITLEAVLCHPFMLK 269
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 162 bits (411), Expect = 2e-39
Identities = 95/265 (35%), Positives = 145/265 (53%), Gaps = 23/265 (8%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G+ +V + G+ A+K I KS P +E EI ++K
Sbjct: 29 LGSGAFSEVFLVKQRLTGKLFALKCIKKS--------------PAFRDSSLENEIAVLKK 74
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
+ H N++ L D++E++ Y+V++ V GELF+ ++ERG E +A +Q++ + Y
Sbjct: 75 IKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYL 134
Query: 143 HALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEIVSG 199
H GIVHRDLKPENLL + + + DFG++ +E ++ ++ T+CG+P Y APE+++
Sbjct: 135 HENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKME-QNGIMSTACGTPGYVAPEVLAQ 193
Query: 200 LPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSG--KFEMPGDDEISSEA 257
PY D WS GVI Y LL G PF EE + L K++ G +FE P D+IS A
Sbjct: 194 KPY-SKAVDCWSIGVITYILLCGYPPFYEETES--KLFEKIKEGYYEFESPFWDDISESA 250
Query: 258 QDLIARILTVDPEQRIKTREILKHP 282
+D I +L DP +R + L HP
Sbjct: 251 KDFICHLLEKDPNERYTCEKALSHP 275
>Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 473
Score = 162 bits (410), Expect = 3e-39
Identities = 96/271 (35%), Positives = 160/271 (58%), Gaps = 23/271 (8%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+++ S LG G+T V + + A+K++ K++ D + + E
Sbjct: 46 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTV------------DKKI----VRTE 89
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I ++ L+HPN+++L +++ET ++ +VLE V GELF+ +VE+G E +A +QI+
Sbjct: 90 IGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQIL 149
Query: 137 IGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
++Y H GIVHRDLKPENLL +K+ADFG++ + L++T CG+P Y A
Sbjct: 150 EAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCA 209
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGK--FEMPGDD 251
PEI+ G Y G E D+WS G+I Y LL G PF +E G+ + + ++ + + F P D
Sbjct: 210 PEILRGCAY-GPEVDMWSVGIITYILLCGFEPFYDERGD-QFMFRRILNCEYYFISPWWD 267
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKHP 282
E+S A+DL+ +++ +DP++R+ T + L+HP
Sbjct: 268 EVSLNAKDLVRKLIVLDPKKRLTTFQALQHP 298
>At5g63650 [T] KOG0583 Serine/threonine protein kinase
Length = 360
Score = 162 bits (409), Expect = 4e-39
Identities = 91/236 (38%), Positives = 133/236 (55%), Gaps = 15/236 (6%)
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
+ REII + L HPN++R +V T L +V+EY GELF + G E EA FF
Sbjct: 45 VAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFF 104
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFN--VKLADFGMAALESKDKLLETSCGSPH 190
+Q+I G+ YCH+L I HRDLK EN LLD +K+ DFG + +++ G+P
Sbjct: 105 QQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPA 164
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDG--NIRNLLLKVQSGKFEMP 248
Y APE++S Y G +DVWSCGV LY +L G PF++ D N R + ++ + ++++P
Sbjct: 165 YIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIP 224
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDT 304
IS E + L++RI + +RI +EI KHP ++NLP+E T
Sbjct: 225 DYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWY-----------LKNLPKELT 269
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 161 bits (408), Expect = 5e-39
Identities = 94/271 (34%), Positives = 142/271 (51%), Gaps = 11/271 (4%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREI-IIMK 81
LG G + V ++ Q+ AVK+I + G + L +E+ I+ K
Sbjct: 26 LGRGVSSVVRRCIHKPTSQEYAVKVI-----DVTGGGSFSPEEVRELREATLKEVDILRK 80
Query: 82 LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISY 141
+ HPN+++L D +ET+ ++V + +++GELF+ L E+ L E E + R ++ I
Sbjct: 81 VSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVICT 140
Query: 142 CHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEIV---- 197
H L IVHRDLKPEN+LLD N+KL DFG + + L CG+P Y APEI+
Sbjct: 141 LHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSM 200
Query: 198 -SGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISSE 256
P +G E D+WS GVI+Y LL G PF + ++ + +F P D+ S
Sbjct: 201 NEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDT 260
Query: 257 AQDLIARILTVDPEQRIKTREILKHPLLRKY 287
+DL++R L V P+ R E L HP ++Y
Sbjct: 261 VKDLVSRFLVVQPQNRYTAEEALAHPFFQQY 291
>At4g33950 [T] KOG0583 Serine/threonine protein kinase
Length = 357
Score = 161 bits (407), Expect = 6e-39
Identities = 95/269 (35%), Positives = 143/269 (52%), Gaps = 19/269 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
++L +G G+ G + ++ + AVK I + + + ++RE
Sbjct: 21 YELVKDIGSGNFGVARLMRDKQSNELVAVKYIERG---------------EKIDENVKRE 65
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
II + L HPN++R +V T L +V+EY GELF + G E+EA FF+Q+I
Sbjct: 66 IINHRSLRHPNIVRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLI 125
Query: 137 IGISYCHALGIVHRDLKPENLLLDHK--FNVKLADFGMAALESKDKLLETSCGSPHYAAP 194
G+SYCHA+ + HRDLK EN LLD +K+ DFG + +++ G+P Y AP
Sbjct: 126 SGVSYCHAMQVCHRDLKLENTLLDGSPAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAP 185
Query: 195 EIVSGLPYHGFESDVWSCGVILYALLTGRLPFD--EEDGNIRNLLLKVQSGKFEMPGDDE 252
E++ Y G +DVWSCGV LY +L G PF+ EE N R + ++ + ++ +P
Sbjct: 186 EVLLKKEYDGKVADVWSCGVTLYVMLVGAYPFEDPEEPKNFRKTIHRILNVQYAIPDYVH 245
Query: 253 ISSEAQDLIARILTVDPEQRIKTREILKH 281
IS E + LI+RI DP +RI EI H
Sbjct: 246 ISPECRHLISRIFVADPAKRISIPEIRNH 274
>At1g60940 [T] KOG0583 Serine/threonine protein kinase
Length = 361
Score = 161 bits (407), Expect = 6e-39
Identities = 88/236 (37%), Positives = 135/236 (56%), Gaps = 15/236 (6%)
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
+ REII + L HPN++R +V T + + +EY GELF + G E+EA FF
Sbjct: 45 VAREIINHRSLRHPNIIRFKEVVLTPTHIAIAMEYAAGGELFERICSAGRFSEDEARYFF 104
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHK--FNVKLADFGMAALESKDKLLETSCGSPH 190
+Q+I G+SYCHA+ I HRDLK EN LLD +K+ DFG + + +++ G+P
Sbjct: 105 QQLISGVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSMPKSTVGTPA 164
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDG--NIRNLLLKVQSGKFEMP 248
Y APE++S Y G +DVWSCGV LY +L G PF++++ N + + ++ + K+++P
Sbjct: 165 YIAPEVLSRGEYDGKMADVWSCGVTLYVMLVGAYPFEDQEDPKNFKKTIQRIMAVKYKIP 224
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDT 304
IS + + L++RI + +RI +I KHP ++NLPRE T
Sbjct: 225 DYVHISQDCKHLLSRIFVTNSNKRITIGDIKKHPWF-----------LKNLPRELT 269
>Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 499
Score = 160 bits (406), Expect = 8e-39
Identities = 104/272 (38%), Positives = 150/272 (54%), Gaps = 21/272 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
++L LG G+ V GQ A KII+ +A+ + ERE
Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQGYAAKIINTKKLSARDHQKL------------ERE 61
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I +LL HPN++RL+D Y+V + V GELF +V R E +A +QI+
Sbjct: 62 ARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMA-ALESKDKLLETSCGSPHYA 192
+++CH GIVHRDLKPENLLL K VKLADFG+A ++ + G+P Y
Sbjct: 122 ESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD-- 250
+PE++ PY G D+W+CGVILY LL G PF +ED + L ++++G ++ P
Sbjct: 182 SPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQH--RLYQQIKAGAYDFPSPEW 238
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHP 282
D ++ EA+DLI ++LT++P +RI E LKHP
Sbjct: 239 DTVTPEAKDLINKMLTINPAKRITASEALKHP 270
>At1g10940 [T] KOG0583 Serine/threonine protein kinase
Length = 363
Score = 160 bits (406), Expect = 8e-39
Identities = 91/236 (38%), Positives = 135/236 (56%), Gaps = 15/236 (6%)
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
+ REII + L HPN++R +V T L + +EY GELF + G E+EA FF
Sbjct: 45 VAREIINHRSLRHPNIIRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFF 104
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHK--FNVKLADFGMAALESKDKLLETSCGSPH 190
+Q+I G+SYCHA+ I HRDLK EN LLD +K+ DFG + +++ G+P
Sbjct: 105 QQLISGVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSRPKSTVGTPA 164
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDG--NIRNLLLKVQSGKFEMP 248
Y APE++S Y G +DVWSCGV LY +L G PF++++ N R + K+ + ++++P
Sbjct: 165 YIAPEVLSRREYDGKMADVWSCGVTLYVMLVGAYPFEDQEDPKNFRKTIQKIMAVQYKIP 224
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDT 304
IS + ++L++RI + +RI EI KH S ++NLPRE T
Sbjct: 225 DYVHISQDCKNLLSRIFVANSLKRITIAEIKKH-----------SWFLKNLPRELT 269
>Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 505
Score = 160 bits (404), Expect = 1e-38
Identities = 106/312 (33%), Positives = 168/312 (52%), Gaps = 25/312 (8%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQ-----------GSTMIG 62
+ +KL S +G G+ G V +AYNE++ + A+K++SK Q G
Sbjct: 125 LNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQG 184
Query: 63 GNDPDVLPYG-IEREIIIMKLLNHPNVLRLYDVWE--TSKDLYMVLEYVEKGELFNLLVE 119
G +LP + +EI I+K L+H NV++L +V + +LY+V + + KG + + +
Sbjct: 185 GPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCD 244
Query: 120 RGPLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMA-ALESK 178
+ P E +A + R +I+G+ Y H IVHRD+KP NLLL +VK+ADFG++ E
Sbjct: 245 K-PFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGN 303
Query: 179 DKLLETSCGSPHYAAPEIV--SGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNL 236
D L ++ G+P + APE + SG + G DVW+ GV LY + G+ PF D I L
Sbjct: 304 DAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPF--IDDFILAL 361
Query: 237 LLKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK-----YPSIK 291
K+++ P + EIS E +DLI ++L +PE RI +I HP + K PS +
Sbjct: 362 HRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLPSEE 421
Query: 292 DSKSIRNLPRED 303
+ S+ + E+
Sbjct: 422 EHCSVVEVTEEE 433
>At1g78290 [T] KOG0583 Serine/threonine protein kinase
Length = 343
Score = 160 bits (404), Expect = 1e-38
Identities = 95/255 (37%), Positives = 142/255 (55%), Gaps = 17/255 (6%)
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
++REI+ + L HPN++R +V T+ L +V+EY GELF + G E+EA FF
Sbjct: 45 VQREIMNHRSLIHPNIIRFKEVLLTATHLALVMEYAAGGELFGRICSAGRFSEDEARFFF 104
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLD--HKFNVKLADFGMAALESKDKLLETSCGSPH 190
+Q+I G++YCH+L I HRDLK EN LLD VK+ DFG + +T+ G+P
Sbjct: 105 QQLISGVNYCHSLQICHRDLKLENTLLDGSEAPRVKICDFGYSKSGVLHSQPKTTVGTPA 164
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDE--EDGNIRNLLLKVQSGKFEMP 248
Y APE++S Y G +DVWSCGV LY +L G PF++ + + R + ++ ++ +P
Sbjct: 165 YIAPEVLSTKEYDGKIADVWSCGVTLYVMLVGAYPFEDPSDPKDFRKTIGRILKAQYAIP 224
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNP 308
+S E + L++RI +PE+RI EI H S ++NLP E Y
Sbjct: 225 DYVRVSDECRHLLSRIFVANPEKRITIEEIKNH-----------SWFLKNLPVE-MYEGS 272
Query: 309 LSLEG-GNQCVDETI 322
L + G Q V+E +
Sbjct: 273 LMMNGPSTQTVEEIV 287
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 159 bits (403), Expect = 2e-38
Identities = 95/271 (35%), Positives = 148/271 (54%), Gaps = 14/271 (5%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREI-IIMK 81
+G G + V + G + AVKI+ + + + + + RE I+ +
Sbjct: 30 IGRGVSSVVRRCVHRATGHEFAVKIMEVT------AERLSPEQLEEVREATRRETHILRQ 83
Query: 82 LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISY 141
+ HP+++ L D +E+S +++V + + KGELF+ L E+ L E E R ++ +S+
Sbjct: 84 VAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSF 143
Query: 142 CHALGIVHRDLKPENLLLDHKFNVKLADFGMAA-LESKDKLLETSCGSPHYAAPEIV--- 197
HA IVHRDLKPEN+LLD ++L+DFG + LE +KL E CG+P Y APEI+
Sbjct: 144 LHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLREL-CGTPGYLAPEILKCS 202
Query: 198 --SGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISS 255
P +G E D+W+CGVIL+ LL G PF + ++ +F P D+ SS
Sbjct: 203 MDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSS 262
Query: 256 EAQDLIARILTVDPEQRIKTREILKHPLLRK 286
+DLI+R+L VDPE R+ + L+HP +
Sbjct: 263 TVKDLISRLLQVDPEARLTAEQALQHPFFER 293
>7298323 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 514
Score = 159 bits (403), Expect = 2e-38
Identities = 92/271 (33%), Positives = 144/271 (52%), Gaps = 20/271 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
W L TLG G+ G+V + N G+ A+K++ PD + +E
Sbjct: 22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLK------------KHPDAAN-SVRKE 68
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGP--LPENEAVRFFRQ 134
+ I K+L ++LR + Y+ LEY GELF+ + E +P++EA R+F Q
Sbjct: 69 VCIQKMLQDKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIGEEPDVGMPQHEAQRYFTQ 128
Query: 135 IIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAAL---ESKDKLLETSCGSPHY 191
++ G++Y H GI HRDLKPENLLLD NVK++DFGMA + + K++LL+ CG+ Y
Sbjct: 129 LLSGLNYLHQRGIAHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPY 188
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD- 250
APE++ YH +D+WSCGVIL +L G LP+D+ N + +++
Sbjct: 189 VAPEVLQ-KAYHAQPADLWSCGVILVTMLAGELPWDQPSTNCTEFTNWRDNDHWQLQTPW 247
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKH 281
++ + A L+ ++L P R+ + L H
Sbjct: 248 SKLDTLAISLLRKLLATSPGTRLTLEKTLDH 278
>At5g66880 [T] KOG0583 Serine/threonine protein kinase
Length = 361
Score = 159 bits (402), Expect = 2e-38
Identities = 94/263 (35%), Positives = 139/263 (52%), Gaps = 19/263 (7%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
+G G+ G + ++ + AVK I + D + ++REII +
Sbjct: 28 IGSGNFGVARLMRDKLTKELVAVKYIERG---------------DKIDENVQREIINHRS 72
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L HPN++R +V T L +++EY GEL+ + G E+EA FF+Q++ G+SYC
Sbjct: 73 LRHPNIVRFKEVILTPTHLAIIMEYASGGELYERICNAGRFSEDEARFFFQQLLSGVSYC 132
Query: 143 HALGIVHRDLKPENLLLDHK--FNVKLADFGMAALESKDKLLETSCGSPHYAAPEIVSGL 200
H++ I HRDLK EN LLD +K+ DFG + +++ G+P Y APE++
Sbjct: 133 HSMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLRQ 192
Query: 201 PYHGFESDVWSCGVILYALLTGRLPFD--EEDGNIRNLLLKVQSGKFEMPGDDEISSEAQ 258
Y G +DVWSCGV LY +L G PF+ EE + R + ++ S K+ +P D IS E
Sbjct: 193 EYDGKIADVWSCGVTLYVMLVGAYPFEDPEEPRDYRKTIQRILSVKYSIPDDIRISPECC 252
Query: 259 DLIARILTVDPEQRIKTREILKH 281
LI+RI DP RI EI H
Sbjct: 253 HLISRIFVADPATRISIPEIKTH 275
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 159 bits (402), Expect = 2e-38
Identities = 87/279 (31%), Positives = 150/279 (53%), Gaps = 16/279 (5%)
Query: 8 TLKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPD 67
T K ++ +++G LG G G+V +A A+K+I K
Sbjct: 13 TEKQWSLADFEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKYK---------- 62
Query: 68 VLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENE 127
+ + + RE+ I L HPN+LRL+ + ++ ++++LEY GEL+ +L + G L E +
Sbjct: 63 -IHHQLRREMEIQTSLRHPNILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQ 121
Query: 128 AVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCG 187
A + + ++YCH ++HRD+KPENLLLDH+ +K+ADFG + S + +T CG
Sbjct: 122 AATYIASLSQALAYCHGKCVIHRDIKPENLLLDHEGRLKIADFGWSVQSSNKR--KTMCG 179
Query: 188 SPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEM 247
+ Y APE+V H + D W+ G++ Y L G PF+ E + ++ ++
Sbjct: 180 TLDYLAPEMVENRD-HDYAVDNWTLGILCYEFLYGNPPFEAE--SQKDTFKRILKIDLSF 236
Query: 248 PGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
P +S EA++LI+++L DP +R+ +I++HP + K
Sbjct: 237 PLTPNVSEEAKNLISQLLVKDPSKRLSIEKIMQHPWIVK 275
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 159 bits (401), Expect = 3e-38
Identities = 100/274 (36%), Positives = 153/274 (55%), Gaps = 14/274 (5%)
Query: 17 WKLGSTLGVGSTGKVVMAYN-ETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVL----PY 71
+ L LG G+ +V +A + ++ G+ AVKII K + ++ N+ VL
Sbjct: 31 YNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESL--ENEIRVLRRFSAN 88
Query: 72 GIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRF 131
+ + + L HPN+++L + +E +Y+V+E V GELF+ +VE+G E +A
Sbjct: 89 HFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHL 148
Query: 132 FRQIIIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGS 188
RQI+ + Y H G+VHRDLKPENLL D + ++DFG++ +E ++ T+CG+
Sbjct: 149 IRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSG-IMATACGT 207
Query: 189 PHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEM 247
P Y APE+++ PY G DVWS GVI Y LL G PF DE D N+ +LK +F+
Sbjct: 208 PGYVAPEVLAQKPY-GKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILK-GDFEFDS 265
Query: 248 PGDDEISSEAQDLIARILTVDPEQRIKTREILKH 281
P DEIS A+ I ++ V E+R ++ L H
Sbjct: 266 PYWDEISESAKHFIKNLMCVTVEKRYTCKQALGH 299
>Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 159 bits (401), Expect = 3e-38
Identities = 103/272 (37%), Positives = 150/272 (54%), Gaps = 17/272 (6%)
Query: 20 GSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIII 79
G LG G V ++ G Q A K I K S+ G + D IERE+ I
Sbjct: 16 GEELGSGQFAVVKKCREKSTGLQYAAKFIKK---RRTKSSRRGVSRED-----IEREVSI 67
Query: 80 MKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGI 139
+K + HPNV+ L++V+E D+ ++LE V GELF+ L E+ L E EA F +QI+ G+
Sbjct: 68 LKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGV 127
Query: 140 SYCHALGIVHRDLKPEN-LLLDH---KFNVKLADFGMAALESKDKLLETSCGSPHYAAPE 195
Y H+L I H DLKPEN +LLD K +K+ DFG+A + G+P + APE
Sbjct: 128 YYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPE 187
Query: 196 IVSGLPYHGFESDVWSCGVILYALLTGRLPF--DEEDGNIRNLLLKVQSGKFEMPGDDEI 253
IV+ P G E+D+WS GVI Y LL+G PF D + + N + + +FE
Sbjct: 188 IVNYEPL-GLEADMWSIGVITYILLSGASPFLGDTKQETLAN--VSAVNYEFEDEYFSNT 244
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
S+ A+D I R+L DP++R+ ++ L+HP ++
Sbjct: 245 SALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 276
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 821
Score = 158 bits (400), Expect = 4e-38
Identities = 100/287 (34%), Positives = 153/287 (52%), Gaps = 33/287 (11%)
Query: 19 LGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREII 78
+ +G G+ V A T G+ AVKIISK +IG D G+ RE+
Sbjct: 200 IDEVVGQGAFATVKKAIERTTGKTFAVKIISKR-------KVIGNMD------GVTRELE 246
Query: 79 IMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIG 138
+++ LNHP ++RL +E ++ YMV+E+V G+L + + G + E+ RQI+
Sbjct: 247 VLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTA 306
Query: 139 ISYCHALGIVHRDLKPENLLL--DHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEI 196
I Y H++GI HRDLKP+N+L+ D VK+ DFG+A ++ ++T CG+ Y APE+
Sbjct: 307 IKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEV 366
Query: 197 VSG----LPYHGFES--------DVWSCGVILYALLTGRLPFDEEDGNIRNLLLK-VQSG 243
+ G + +E D+WS G ++Y +LTG LPF G+ ++ L K + G
Sbjct: 367 IRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPF---SGSTQDQLYKQIGRG 423
Query: 244 KF-EMP-GDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYP 288
+ E P D IS EA+D I +L VDP R + L HP ++ P
Sbjct: 424 SYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWIKMSP 470
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 158 bits (400), Expect = 4e-38
Identities = 89/267 (33%), Positives = 151/267 (56%), Gaps = 13/267 (4%)
Query: 22 TLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMK 81
TLG G+ V +A G+ A+KII+K ++ ++ +REI I+K
Sbjct: 172 TLGSGTFAVVKLAVEVNSGKWYAIKIINKR------KILLTSSEKRATEM-FQREIDILK 224
Query: 82 LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISY 141
L+HP V++ ++++E +L++V+EYVE G+L + L+ G + E + +Q++ + +
Sbjct: 225 SLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLH 284
Query: 142 CHALGIVHRDLKPENLLLDHKFNVKLADFGMA-ALESKDKLLETSCGSPHYAAPEIVSGL 200
H G+ HRD+KPEN+L+ + F++K++DFG+A + LET CG+ Y APE++
Sbjct: 285 LHKQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGTGTFLETFCGTMGYLAPEVLKSK 344
Query: 201 PYH---GFES--DVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISS 255
+ G++ D+WS G +LY +LT +PF L+ + E ++EIS
Sbjct: 345 NVNLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEISE 404
Query: 256 EAQDLIARILTVDPEQRIKTREILKHP 282
E DLI R+L ++PE+RI E L+HP
Sbjct: 405 EGIDLINRMLEINPEKRISESEALQHP 431
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 158 bits (400), Expect = 4e-38
Identities = 96/284 (33%), Positives = 151/284 (52%), Gaps = 19/284 (6%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G + LG +G GS V +A + + G + AVK I K + + + + +
Sbjct: 7 VGDYALGPRIGSGSFAVVWLAKHRSSGLEVAVKEIDKKLLSPK------------VRDNL 54
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
+EI I+ ++HPN++R Y+ ET +++VLEY G+L + G +PE A F R
Sbjct: 55 LKEISILSTIDHPNIIRFYEAIETGDRIFLVLEYCSGGDLAGYINRHGKVPEAVAKHFMR 114
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKF---NVKLADFGMAALESKDKLLETSCGSPH 190
Q+ +G+ +HRDLKP+NLLL K +K+ DFG A + + + ET CGSP
Sbjct: 115 QLALGLQVLQEKHFIHRDLKPQNLLLSSKEVTPLLKIGDFGFARSLTPESMAETFCGSPL 174
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
Y APEI+ Y ++D+WS G IL+ L+TG+ PFD + +I+ V+ + + P D
Sbjct: 175 YMAPEIIRNQKYDA-KADLWSAGAILFQLVTGKPPFD-GNNHIQLFHNIVRDTELKFPED 232
Query: 251 --DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKD 292
+EI + DL +L +P +R+ RE H LR+ I D
Sbjct: 233 TRNEIHPDCVDLCRSLLRRNPIERLTFREFFNHMFLREPRQIPD 276
>CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 158 bits (399), Expect = 5e-38
Identities = 101/265 (38%), Positives = 147/265 (55%), Gaps = 20/265 (7%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G+ V ++T G + A KII+ +A+ + ERE I +
Sbjct: 18 LGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL------------EREARICRK 65
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L HPN++RL+D + Y+V + V GELF +V R E +A +QI+ I+YC
Sbjct: 66 LQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYC 125
Query: 143 HALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYAAPEIVSG 199
H+ GIVHRDLKPENLLL K VKLADFG+A + + G+P Y +PE++
Sbjct: 126 HSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKK 185
Query: 200 LPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD--DEISSEA 257
PY D+W+CGVILY LL G PF +ED + L ++++G ++ P D ++ EA
Sbjct: 186 DPY-SKPVDIWACGVILYILLVGYPPFWDEDQH--RLYAQIKAGAYDYPSPEWDTVTPEA 242
Query: 258 QDLIARILTVDPEQRIKTREILKHP 282
+ LI +LTV+P++RI + LK P
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVP 267
>CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 158 bits (399), Expect = 5e-38
Identities = 101/265 (38%), Positives = 147/265 (55%), Gaps = 20/265 (7%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G+ V ++T G + A KII+ +A+ + ERE I +
Sbjct: 18 LGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL------------EREARICRK 65
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L HPN++RL+D + Y+V + V GELF +V R E +A +QI+ I+YC
Sbjct: 66 LQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYC 125
Query: 143 HALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYAAPEIVSG 199
H+ GIVHRDLKPENLLL K VKLADFG+A + + G+P Y +PE++
Sbjct: 126 HSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKK 185
Query: 200 LPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD--DEISSEA 257
PY D+W+CGVILY LL G PF +ED + L ++++G ++ P D ++ EA
Sbjct: 186 DPY-SKPVDIWACGVILYILLVGYPPFWDEDQH--RLYAQIKAGAYDYPSPEWDTVTPEA 242
Query: 258 QDLIARILTVDPEQRIKTREILKHP 282
+ LI +LTV+P++RI + LK P
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVP 267
>CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 350
Score = 158 bits (399), Expect = 5e-38
Identities = 101/265 (38%), Positives = 147/265 (55%), Gaps = 20/265 (7%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G+ V ++T G + A KII+ +A+ + ERE I +
Sbjct: 18 LGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL------------EREARICRK 65
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L HPN++RL+D + Y+V + V GELF +V R E +A +QI+ I+YC
Sbjct: 66 LQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYC 125
Query: 143 HALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYAAPEIVSG 199
H+ GIVHRDLKPENLLL K VKLADFG+A + + G+P Y +PE++
Sbjct: 126 HSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKK 185
Query: 200 LPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD--DEISSEA 257
PY D+W+CGVILY LL G PF +ED + L ++++G ++ P D ++ EA
Sbjct: 186 DPY-SKPVDIWACGVILYILLVGYPPFWDEDQH--RLYAQIKAGAYDYPSPEWDTVTPEA 242
Query: 258 QDLIARILTVDPEQRIKTREILKHP 282
+ LI +LTV+P++RI + LK P
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVP 267
>CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 158 bits (399), Expect = 5e-38
Identities = 101/265 (38%), Positives = 147/265 (55%), Gaps = 20/265 (7%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G+ V ++T G + A KII+ +A+ + ERE I +
Sbjct: 18 LGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL------------EREARICRK 65
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L HPN++RL+D + Y+V + V GELF +V R E +A +QI+ I+YC
Sbjct: 66 LQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYC 125
Query: 143 HALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYAAPEIVSG 199
H+ GIVHRDLKPENLLL K VKLADFG+A + + G+P Y +PE++
Sbjct: 126 HSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKK 185
Query: 200 LPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD--DEISSEA 257
PY D+W+CGVILY LL G PF +ED + L ++++G ++ P D ++ EA
Sbjct: 186 DPY-SKPVDIWACGVILYILLVGYPPFWDEDQH--RLYAQIKAGAYDYPSPEWDTVTPEA 242
Query: 258 QDLIARILTVDPEQRIKTREILKHP 282
+ LI +LTV+P++RI + LK P
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVP 267
>CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 158 bits (399), Expect = 5e-38
Identities = 101/265 (38%), Positives = 147/265 (55%), Gaps = 20/265 (7%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G+ V ++T G + A KII+ +A+ + ERE I +
Sbjct: 18 LGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL------------EREARICRK 65
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L HPN++RL+D + Y+V + V GELF +V R E +A +QI+ I+YC
Sbjct: 66 LQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYC 125
Query: 143 HALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYAAPEIVSG 199
H+ GIVHRDLKPENLLL K VKLADFG+A + + G+P Y +PE++
Sbjct: 126 HSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKK 185
Query: 200 LPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD--DEISSEA 257
PY D+W+CGVILY LL G PF +ED + L ++++G ++ P D ++ EA
Sbjct: 186 DPY-SKPVDIWACGVILYILLVGYPPFWDEDQH--RLYAQIKAGAYDYPSPEWDTVTPEA 242
Query: 258 QDLIARILTVDPEQRIKTREILKHP 282
+ LI +LTV+P++RI + LK P
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVP 267
>CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 518
Score = 158 bits (399), Expect = 5e-38
Identities = 101/265 (38%), Positives = 147/265 (55%), Gaps = 20/265 (7%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G+ V ++T G + A KII+ +A+ + ERE I +
Sbjct: 18 LGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL------------EREARICRK 65
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L HPN++RL+D + Y+V + V GELF +V R E +A +QI+ I+YC
Sbjct: 66 LQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYC 125
Query: 143 HALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYAAPEIVSG 199
H+ GIVHRDLKPENLLL K VKLADFG+A + + G+P Y +PE++
Sbjct: 126 HSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKK 185
Query: 200 LPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD--DEISSEA 257
PY D+W+CGVILY LL G PF +ED + L ++++G ++ P D ++ EA
Sbjct: 186 DPY-SKPVDIWACGVILYILLVGYPPFWDEDQH--RLYAQIKAGAYDYPSPEWDTVTPEA 242
Query: 258 QDLIARILTVDPEQRIKTREILKHP 282
+ LI +LTV+P++RI + LK P
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVP 267
>CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 158 bits (399), Expect = 5e-38
Identities = 101/265 (38%), Positives = 147/265 (55%), Gaps = 20/265 (7%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G+ V ++T G + A KII+ +A+ + ERE I +
Sbjct: 18 LGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL------------EREARICRK 65
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L HPN++RL+D + Y+V + V GELF +V R E +A +QI+ I+YC
Sbjct: 66 LQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYC 125
Query: 143 HALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYAAPEIVSG 199
H+ GIVHRDLKPENLLL K VKLADFG+A + + G+P Y +PE++
Sbjct: 126 HSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKK 185
Query: 200 LPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD--DEISSEA 257
PY D+W+CGVILY LL G PF +ED + L ++++G ++ P D ++ EA
Sbjct: 186 DPY-SKPVDIWACGVILYILLVGYPPFWDEDQH--RLYAQIKAGAYDYPSPEWDTVTPEA 242
Query: 258 QDLIARILTVDPEQRIKTREILKHP 282
+ LI +LTV+P++RI + LK P
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVP 267
>CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 482
Score = 158 bits (399), Expect = 5e-38
Identities = 101/265 (38%), Positives = 147/265 (55%), Gaps = 20/265 (7%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G+ V ++T G + A KII+ +A+ + ERE I +
Sbjct: 18 LGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL------------EREARICRK 65
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L HPN++RL+D + Y+V + V GELF +V R E +A +QI+ I+YC
Sbjct: 66 LQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYC 125
Query: 143 HALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYAAPEIVSG 199
H+ GIVHRDLKPENLLL K VKLADFG+A + + G+P Y +PE++
Sbjct: 126 HSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKK 185
Query: 200 LPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD--DEISSEA 257
PY D+W+CGVILY LL G PF +ED + L ++++G ++ P D ++ EA
Sbjct: 186 DPY-SKPVDIWACGVILYILLVGYPPFWDEDQH--RLYAQIKAGAYDYPSPEWDTVTPEA 242
Query: 258 QDLIARILTVDPEQRIKTREILKHP 282
+ LI +LTV+P++RI + LK P
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVP 267
>CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 720
Score = 158 bits (399), Expect = 5e-38
Identities = 101/265 (38%), Positives = 147/265 (55%), Gaps = 20/265 (7%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G+ V ++T G + A KII+ +A+ + ERE I +
Sbjct: 18 LGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL------------EREARICRK 65
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L HPN++RL+D + Y+V + V GELF +V R E +A +QI+ I+YC
Sbjct: 66 LQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYC 125
Query: 143 HALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYAAPEIVSG 199
H+ GIVHRDLKPENLLL K VKLADFG+A + + G+P Y +PE++
Sbjct: 126 HSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKK 185
Query: 200 LPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD--DEISSEA 257
PY D+W+CGVILY LL G PF +ED + L ++++G ++ P D ++ EA
Sbjct: 186 DPY-SKPVDIWACGVILYILLVGYPPFWDEDQH--RLYAQIKAGAYDYPSPEWDTVTPEA 242
Query: 258 QDLIARILTVDPEQRIKTREILKHP 282
+ LI +LTV+P++RI + LK P
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVP 267
>CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 559
Score = 158 bits (399), Expect = 5e-38
Identities = 101/265 (38%), Positives = 147/265 (55%), Gaps = 20/265 (7%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G+ V ++T G + A KII+ +A+ + ERE I +
Sbjct: 18 LGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL------------EREARICRK 65
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L HPN++RL+D + Y+V + V GELF +V R E +A +QI+ I+YC
Sbjct: 66 LQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYC 125
Query: 143 HALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYAAPEIVSG 199
H+ GIVHRDLKPENLLL K VKLADFG+A + + G+P Y +PE++
Sbjct: 126 HSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKK 185
Query: 200 LPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD--DEISSEA 257
PY D+W+CGVILY LL G PF +ED + L ++++G ++ P D ++ EA
Sbjct: 186 DPY-SKPVDIWACGVILYILLVGYPPFWDEDQH--RLYAQIKAGAYDYPSPEWDTVTPEA 242
Query: 258 QDLIARILTVDPEQRIKTREILKHP 282
+ LI +LTV+P++RI + LK P
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVP 267
>At5g08590 [T] KOG0583 Serine/threonine protein kinase
Length = 353
Score = 158 bits (399), Expect = 5e-38
Identities = 88/234 (37%), Positives = 132/234 (55%), Gaps = 15/234 (6%)
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
+ REII + L HPN++R +V T L +V+EY GELF+ + G E EA FF
Sbjct: 45 VAREIINHRSLKHPNIIRFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFF 104
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFN--VKLADFGMAALESKDKLLETSCGSPH 190
+Q+I G+ YCH+L I HRDLK EN LLD +K+ DFG + +++ G+P
Sbjct: 105 QQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSILHSRPKSTVGTPA 164
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDE--EDGNIRNLLLKVQSGKFEMP 248
Y APE++S Y G +DVWSCGV LY +L G PF++ + N R + ++ + ++++P
Sbjct: 165 YIAPEVLSRREYDGKHADVWSCGVTLYVMLVGAYPFEDPNDPKNFRKTIQRIMAVQYKIP 224
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPRE 302
IS E + L++RI + +RI +EI HP ++NLP+E
Sbjct: 225 DYVHISQECKHLLSRIFVTNSAKRITLKEIKNHPWY-----------LKNLPKE 267
>7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 493
Score = 158 bits (399), Expect = 5e-38
Identities = 100/266 (37%), Positives = 149/266 (55%), Gaps = 21/266 (7%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G+ V ++ G + A KII+ A+ + ERE I +
Sbjct: 20 LGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKL------------EREARICRK 67
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L+HPN++RL+D + Y+V + V GELF +V R E +A +QI+ +++C
Sbjct: 68 LHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHC 127
Query: 143 HALGIVHRDLKPENLLLDHKFN---VKLADFGMA-ALESKDKLLETSCGSPHYAAPEIVS 198
H G+VHRDLKPENLLL K VKLADFG+A ++ + G+P Y +PE++
Sbjct: 128 HQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLK 187
Query: 199 GLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD--DEISSE 256
PY G D+W+CGVILY LL G PF +ED + L ++++G ++ P D ++ E
Sbjct: 188 KEPY-GKSVDIWACGVILYILLVGYPPFWDEDQH--RLYSQIKAGAYDYPSPEWDTVTPE 244
Query: 257 AQDLIARILTVDPEQRIKTREILKHP 282
A++LI ++LTV+P +RI E LKHP
Sbjct: 245 AKNLINQMLTVNPNKRITAAEALKHP 270
>SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 496
Score = 157 bits (398), Expect = 7e-38
Identities = 100/274 (36%), Positives = 155/274 (56%), Gaps = 15/274 (5%)
Query: 16 PWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIER 75
P+ +G +G G+ V + Y++ + AVK ++K S M G V +
Sbjct: 9 PYHIGREIGTGAFASVRLCYDDN-AKIYAVKFVNKKHAT---SCMNAG----VWARRMAS 60
Query: 76 EIIIMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQ 134
EI + KL N H N++ Y+ E + ++VLE+ + G+LF+ + + E+ A +F Q
Sbjct: 61 EIQLHKLCNGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQ 120
Query: 135 IIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAAL---ESKDKLLETSCGSPHY 191
++ GIS+ H+ G+ HRDLKPEN+LLD+ N+K++DFG A+L + K +LL + GSP Y
Sbjct: 121 LMEGISFMHSKGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPY 180
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRN-LLLKVQSGKFEMPGD 250
AAPEI Y G + DVWSCG+IL+ALL G P+DE N + LL K Q +
Sbjct: 181 AAPEITQ--QYDGSKVDVWSCGIILFALLLGNTPWDEAISNTGDYLLYKKQCERPSYHPW 238
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLL 284
+ +S A +I +L DP +R + +++HP L
Sbjct: 239 NLLSPGAYSIITGMLRSDPFKRYSVKHVVQHPWL 272
>ECU08g1480 [R] KOG0586 Serine/threonine protein kinase
Length = 467
Score = 157 bits (398), Expect = 7e-38
Identities = 104/297 (35%), Positives = 151/297 (50%), Gaps = 33/297 (11%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG GS G V+ A + G A+K I K D G+E +I + +
Sbjct: 16 LGSGSYGDVLSAVDNITGMDVAIKFIKK--------------DAGECKRGLESKIQL--I 59
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
LNH N+ +LY TSK+L +VLE V +L + G L E A F Q++ + Y
Sbjct: 60 LNHENICKLYGCISTSKNLVLVLELVRGVDLHRYIRRNGRLEEAYARSLFIQMLRAVDYL 119
Query: 143 HALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEIVSGLPY 202
H IVHRDLK EN+++ + VK+ DFG++ +L CG+P A PEI++G+PY
Sbjct: 120 HTHSIVHRDLKLENVMISGE-TVKICDFGLSTFYDSSSVLRDYCGTPQCAPPEIMNGIPY 178
Query: 203 HGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISSEAQDLIA 262
G E D+W GVILYA++ G+LPF++ D + + V +M D+ +SSE +DLI
Sbjct: 179 IGPEVDIWCLGVILYAMVHGKLPFEDGDTKLSSRHAIVS----KMRIDESLSSELRDLIR 234
Query: 263 RILTVDPEQRIKTREILKHPLL-------RKYPSIKDSKSIRNL-----PREDTYLN 307
+ + D RIK ++++HP + RK D SI L RED N
Sbjct: 235 KTIEPDRSMRIKMDQMMEHPWINSARERYRKSVVFIDDNSIERLAEIGFKREDILRN 291
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 157 bits (396), Expect = 1e-37
Identities = 99/274 (36%), Positives = 150/274 (54%), Gaps = 31/274 (11%)
Query: 20 GSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIII 79
G +G G G V + + G + A K + K G + + RE+ I
Sbjct: 110 GRNIGKGKFGSVRICKSRKNGTEFACKTLKK------------GEET------VHREVEI 151
Query: 80 MKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIG 138
M+ L+ HP V+ L+ V+E S ++V+E G L + +V+ G E A F+ +++
Sbjct: 152 MQHLSGHPRVVTLHAVYEESDCFHLVMELCSGGRLIDQMVKVGRYSEQRAANIFKDLMLV 211
Query: 139 ISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEIVS 198
I+YCH +G+VHRD+KPEN+LL ++LADFG+A +K + L GSP Y APE++S
Sbjct: 212 INYCHEMGVVHRDIKPENILLTAAGKIQLADFGLAMRIAKGQTLSGLAGSPAYVAPEVLS 271
Query: 199 GLPYHGFESDVWSCGVILYALLTGRLPF--DEEDG---NIRNLLLKVQSGKFEMPGDDEI 253
+ + DVWS GV+LYALL+G LPF D D I+N+ L +G +E +
Sbjct: 272 --ENYSEKVDVWSAGVLLYALLSGVLPFKGDSLDAIFEAIKNVKLDFNTGVWE-----SV 324
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRKY 287
S A+DL+AR+LT + RI E+L+HP + Y
Sbjct: 325 SKPARDLLARMLTREESARITADEVLRHPWILFY 358
>CE18454 [T] KOG4717 Serine/threonine protein kinase
Length = 1016
Score = 156 bits (395), Expect = 1e-37
Identities = 100/268 (37%), Positives = 151/268 (56%), Gaps = 21/268 (7%)
Query: 15 GPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIE 74
G + L T+G G V +A + G+ AVKII K+ + ++ I
Sbjct: 25 GLYDLEKTIGQGHFAVVKLAKHVFTGEMVAVKIIDKTKMDEASTSQI------------M 72
Query: 75 REIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLV--ERGPLPENEAVRFF 132
+E+ MKL+ H N++RLY+V +T ++++LE + +L + ++ E+G + E+ A ++F
Sbjct: 73 KEVRCMKLVQHANIVRLYEVLDTQTKIFLILELGDY-DLHDFIIKHEKG-VCESLAQQYF 130
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFN-VKLADFGMAALESKDKLLETSCGSPHY 191
QI+ I YCH L +VHRDLKPEN++ K VKL DFG + + L TSCGS Y
Sbjct: 131 CQIMTAIDYCHQLHVVHRDLKPENVVFFEKLGMVKLTDFGFSNSYEPGEQLNTSCGSLAY 190
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDD 251
+APEI+ G Y DVWS GVILY L+ GRLPF E N L K+ K+ +P D
Sbjct: 191 SAPEILLGDSYDAPAVDVWSLGVILYMLVCGRLPFQE--ANDSETLTKILDCKYSIP--D 246
Query: 252 EISSEAQDLIARILTVDPEQRIKTREIL 279
+S E ++LI +L +P++R +I+
Sbjct: 247 VLSDECRNLIQSMLVREPQKRASLEKIV 274
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 155 bits (392), Expect = 3e-37
Identities = 82/208 (39%), Positives = 128/208 (61%), Gaps = 4/208 (1%)
Query: 76 EIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
EI + + ++HPN++ D +E S ++Y++LE E L LL +R L E E QI
Sbjct: 88 EIKVHQSMSHPNIVGFIDCFEDSTNIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQI 147
Query: 136 IIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLE-TSCGSPHYAAP 194
+ + Y H ++HRDLK N++LD NVK+ DFG+AAL D+ + T CG+P+Y AP
Sbjct: 148 LGALKYMHKKRVIHRDLKLGNIMLDESNNVKIGDFGLAALLMDDEERKMTICGTPNYIAP 207
Query: 195 EIV-SGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
EI+ + H FE D+WS GV++YALL G+ PF +D ++ + K+++ + P + +I
Sbjct: 208 EILFNSKEGHSFEVDLWSAGVVMYALLIGKPPF--QDKEVKTIYRKIKANSYSFPSNVDI 265
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKH 281
S+EA+DLI+ +LT DP R +I+ H
Sbjct: 266 SAEAKDLISSLLTHDPSIRPSIDDIVDH 293
>Hs20545357 [T] KOG0583 Serine/threonine protein kinase
Length = 436
Score = 155 bits (392), Expect = 3e-37
Identities = 87/262 (33%), Positives = 138/262 (52%), Gaps = 16/262 (6%)
Query: 11 GDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLP 70
G IG +++ +G G+ +V + + ++ A+KI+ K+ + + ++
Sbjct: 68 GKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLS-------- 119
Query: 71 YGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVR 130
REI M+ L+HPN++RLY+V ET L++V+EY GELF + G L E E+
Sbjct: 120 ----REISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKL 175
Query: 131 FFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPH 190
F QI+ + + H I+HRDLK EN+ VK+ DFG + + K ++L T CGSP
Sbjct: 176 IFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPP 235
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
YAAPE+ Y G D+W+ GV+LY ++TG +PF E + L + G + +P
Sbjct: 236 YAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAE--TVAKLKKSILEGTYSVP-- 291
Query: 251 DEISSEAQDLIARILTVDPEQR 272
+S LI +L P +R
Sbjct: 292 PHVSEPCHRLIRGVLQQIPTER 313
>At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 490
Score = 155 bits (392), Expect = 3e-37
Identities = 103/272 (37%), Positives = 150/272 (54%), Gaps = 25/272 (9%)
Query: 19 LGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREII 78
LG LG G G + ++ GQ+ A K I K Q DVL REI
Sbjct: 24 LGQVLGQGQFGTTFLCTHKQTGQKLACKSIPKRKLLCQEDY------DDVL-----REIQ 72
Query: 79 IMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIII 137
IM L+ +PNV+R+ +E +K++++V+E E GELF+ +V+RG E EA + + I+
Sbjct: 73 IMHHLSEYPNVVRIESAYEDTKNVHLVMELCEGGELFDRIVKRGHYSEREAAKLIKTIVG 132
Query: 138 GISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYAAP 194
+ CH+LG+VHRDLKPEN L D ++K DFG++ + + GS +Y AP
Sbjct: 133 VVEACHSLGVVHRDLKPENFLFSSSDEDASLKSTDFGLSVFCTPGEAFSELVGSAYYVAP 192
Query: 195 EIVSGLPYHGFESDVWSCGVILYALLTGRLPF--DEEDGNIRNLLLKVQSGK--FEMPGD 250
E++ ++G E DVWS GVILY LL G PF + E G R K+ GK FE+
Sbjct: 193 EVLH--KHYGPECDVWSAGVILYILLCGFPPFWAESEIGIFR----KILQGKLEFEINPW 246
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHP 282
IS A+DLI ++L +P++R+ ++L HP
Sbjct: 247 PSISESAKDLIKKMLESNPKKRLTAHQVLCHP 278
>At2g23030 [T] KOG0583 Serine/threonine protein kinase
Length = 339
Score = 155 bits (392), Expect = 3e-37
Identities = 98/290 (33%), Positives = 144/290 (48%), Gaps = 30/290 (10%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+++ LG G+ G + N+ + AVK I + + + RE
Sbjct: 4 YEMVKDLGFGNFGLARLMRNKQTNELVAVKFIDRGY---------------KIDENVARE 48
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
II + LNHPN++R +V T L +V+EY GELF + G E EA FF+Q+I
Sbjct: 49 IINHRALNHPNIVRFKEVVLTPTHLGIVMEYAAGGELFERISSVGRFSEAEARYFFQQLI 108
Query: 137 IGISYCHALGIVHRDLKPENLLLDHK--FNVKLADFGMAALESKDKLLETSCGSPHYAAP 194
G+ Y HAL I HRDLK EN LLD +K+ DFG + +++ G+P Y AP
Sbjct: 109 CGVHYLHALQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSVLHSNPKSTVGTPAYIAP 168
Query: 195 EIVSGLPYHGFESDVWSCGVILYALLTGRLPFDE--EDGNIRNLLLKVQSGKFEMPGDDE 252
E+ Y G DVWSCGV LY +L G PF++ + N R + K+ + +++PG
Sbjct: 169 EVFCRSEYDGKSVDVWSCGVALYVMLVGAYPFEDPKDPRNFRKTVQKIMAVNYKIPGYVH 228
Query: 253 ISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPRE 302
IS + + L++RI +P R +EI H ++NLPRE
Sbjct: 229 ISEDCRKLLSRIFVANPLHRSTLKEIKSHAWF-----------LKNLPRE 267
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 155 bits (391), Expect = 4e-37
Identities = 97/298 (32%), Positives = 159/298 (52%), Gaps = 25/298 (8%)
Query: 1 MNGNGITTLKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISK---------- 50
+NGN + + +K+G +G G+ V + + G++ A+KII K
Sbjct: 183 VNGNRCSE-SSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKQCAP 241
Query: 51 SIFNAQGSTMIGGNDPDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEK 110
S + ++G + + IE E+ I++ + HPN++ L + ET+ +L++V+E V+
Sbjct: 242 SNTDTSCEAIVGSTE-----HLIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKG 296
Query: 111 GELFNLLVERGPLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLL----DHKFNVK 166
G+LF+ + E + + + Y H L IVHRD+KPENLL+ D ++K
Sbjct: 297 GDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLK 356
Query: 167 LADFGMAALESKDKLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF 226
L DFG+A + + L T CG+P Y APEI++ Y G + D+W+ GVI Y LL G PF
Sbjct: 357 LGDFGLATV--VEGPLYTVCGTPTYVAPEIIAETGY-GLKVDIWAAGVITYILLCGFPPF 413
Query: 227 DEEDGNIRNLLLKVQSGKFEMPGD--DEISSEAQDLIARILTVDPEQRIKTREILKHP 282
E+ +L ++ +GK E P D I+ A++LI+++L V+ E R +IL HP
Sbjct: 414 RSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHP 471
>At3g50500 [T] KOG0583 Serine/threonine protein kinase
Length = 362
Score = 154 bits (390), Expect = 6e-37
Identities = 86/210 (40%), Positives = 122/210 (57%), Gaps = 4/210 (1%)
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
++REII + L HPN++R +V T L +V+EY GEL+ + G E+EA FF
Sbjct: 64 VQREIINHRSLRHPNIVRFKEVILTPSHLAIVMEYAAGGELYERICNAGRFSEDEARFFF 123
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHK--FNVKLADFGMAALESKDKLLETSCGSPH 190
+Q+I G+SYCHA+ I HRDLK EN LLD +K+ DFG + +++ G+P
Sbjct: 124 QQLISGVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSVLHSQPKSTVGTPA 183
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFD--EEDGNIRNLLLKVQSGKFEMP 248
Y APEI+ Y G +DVWSCGV LY +L G PF+ +E + R + ++ S + +P
Sbjct: 184 YIAPEILLRQEYDGKLADVWSCGVTLYVMLVGAYPFEDPQEPRDYRKTIQRILSVTYSIP 243
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREI 278
D +S E + LI+RI DP RI EI
Sbjct: 244 EDLHLSPECRHLISRIFVADPATRITIPEI 273
>At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 154 bits (390), Expect = 6e-37
Identities = 104/300 (34%), Positives = 160/300 (52%), Gaps = 29/300 (9%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ LGS LG G G + + G++ A K I K N+ DV + RE
Sbjct: 132 YNLGSKLGHGQFGTTFVCVEKGTGEEYACKSIPKRKLE---------NEEDV--EDVRRE 180
Query: 77 IIIMK-LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
I IMK LL PNV+ + +E S ++MV+E GELF+ +VERG E +A + I
Sbjct: 181 IEIMKHLLGQPNVISIKGAYEDSVAVHMVMELCRGGELFDRIVERGHYSERKAAHLAKVI 240
Query: 136 IIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
+ + CH+LG++HRDLKPEN L D +K DFG++ + GSP+Y
Sbjct: 241 LGVVQTCHSLGVMHRDLKPENFLFVNDDEDSPLKAIDFGLSMFLKPGENFTDVVGSPYYI 300
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGD- 250
APE+++ +G E+D+WS GV++Y LL+G PF E + I N +V G+ ++ D
Sbjct: 301 APEVLN--KNYGPEADIWSAGVMIYVLLSGSAPFWGETEEEIFN---EVLEGELDLTSDP 355
Query: 251 -DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNPL 309
++S A+DLI ++L +P QR+ +++L HP +R D + + P + T L+ L
Sbjct: 356 WPQVSESAKDLIRKMLERNPIQRLTAQQVLCHPWIR------DEGNAPDTPLDTTVLSRL 409
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 154 bits (389), Expect = 7e-37
Identities = 96/280 (34%), Positives = 149/280 (52%), Gaps = 6/280 (2%)
Query: 76 EIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
EI I K ++HPN+++ D +E ++Y++LE G L LL R L E E F QI
Sbjct: 129 EIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQI 188
Query: 136 IIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAA-LESKDKLLETSCGSPHYAAP 194
I Y H+ ++HRDLK N+ D +N+K+ DFG+AA L ++ + T CG+P+Y AP
Sbjct: 189 CGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAP 248
Query: 195 EIVSGL-PYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
E++ G H FE D+WS GV+LYALL G+ PF D + + +++ F P D I
Sbjct: 249 EVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARD--VNTIYERIKCRDFSFPRDKPI 306
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLR-KYPSIKDSKSIRNLPREDTYLNPLSLE 312
S E + LI IL++DP +R EI+ + R +P S + P + SL
Sbjct: 307 SDEGKILIRDILSLDPIERPSLTEIMDYVWFRGTFPPSIPSTVMSEAPNFEDIPEEQSLV 366
Query: 313 GGNQCVDET-ILQNLVVLWHGRNKEDIITKLMEPGANLEK 351
C++++ +L+++ R K D I+ + LE+
Sbjct: 367 NFKDCMEKSLLLESMSSDKIQRQKRDYISSIKSSIDKLEE 406
>Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 588
Score = 154 bits (389), Expect = 7e-37
Identities = 102/291 (35%), Positives = 157/291 (53%), Gaps = 20/291 (6%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGS----TMIGGNDPD-- 67
+ + L +G GS G V +AYNE A+K++SK Q G P
Sbjct: 162 LNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPG 221
Query: 68 --VLPYG----IEREIIIMKLLNHPNVLRLYDVWETSKD--LYMVLEYVEKGELFNLLVE 119
+ P G + +EI I+K L+HPNV++L +V + + LYMV E V +G + +
Sbjct: 222 GCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL 281
Query: 120 RGPLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMA-ALESK 178
+ PL E++A +F+ +I GI Y H I+HRD+KP NLL+ ++K+ADFG++ +
Sbjct: 282 K-PLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGS 340
Query: 179 DKLLETSCGSPHYAAPEIVSGLP--YHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNL 236
D LL + G+P + APE +S + G DVW+ GV LY + G+ PF +E I L
Sbjct: 341 DALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDE--RIMCL 398
Query: 237 LLKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKY 287
K++S E P +I+ + +DLI R+L +PE RI EI HP + ++
Sbjct: 399 HSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRH 449
>At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 541
Score = 154 bits (389), Expect = 7e-37
Identities = 99/275 (36%), Positives = 149/275 (54%), Gaps = 19/275 (6%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ LG LG G G + + G++ A K ISK ++ D D + RE
Sbjct: 91 YTLGKELGRGQFGVTYLCTENSTGKKYACKSISKK-------KLVTKADKD----DMRRE 139
Query: 77 IIIMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
I IM+ L+ PN++ +E K + +V+E GELF+ ++ +G E A RQI
Sbjct: 140 IQIMQHLSGQPNIVEFKGAYEDEKAVNLVMELCAGGELFDRIIAKGHYTERAAASVCRQI 199
Query: 136 IIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
+ + CH +G++HRDLKPEN LL D K +K DFG++ + K+ GS +Y
Sbjct: 200 VNVVKICHFMGVLHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEGKVYRDIVGSAYYV 259
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGDD 251
APE++ +G E D+WS G+ILY LL+G PF E + I + +L+ FE
Sbjct: 260 APEVLR--RRYGKEVDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGHI-DFESQPWP 316
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
ISS A+DL+ R+LT DP++RI ++L+HP LR+
Sbjct: 317 SISSSAKDLVRRMLTADPKRRISAADVLQHPWLRE 351
>Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 664
Score = 153 bits (386), Expect = 2e-36
Identities = 98/272 (36%), Positives = 148/272 (54%), Gaps = 21/272 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
++L +G G+ V G + A KII+ +A+ + ERE
Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKL------------ERE 61
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I +LL H N++RL+D Y+V + V GELF +V R E +A +QI+
Sbjct: 62 ARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMA-ALESKDKLLETSCGSPHYA 192
+ +CH +G+VHRDLKPENLLL K VKLADFG+A ++ + G+P Y
Sbjct: 122 EAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD-- 250
+PE++ Y G D+W+CGVILY LL G PF +ED + L ++++G ++ P
Sbjct: 182 SPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQH--KLYQQIKAGAYDFPSPEW 238
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHP 282
D ++ EA++LI ++LT++P +RI E LKHP
Sbjct: 239 DTVTPEAKNLINQMLTINPAKRITAHEALKHP 270
>At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 521
Score = 153 bits (386), Expect = 2e-36
Identities = 97/275 (35%), Positives = 150/275 (54%), Gaps = 19/275 (6%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ L LG G G + ++ G++ A K ISK +G + RE
Sbjct: 73 YTLSKELGRGQFGVTYLCTEKSTGKRFACKSISKKKLVTKGDKE-----------DMRRE 121
Query: 77 IIIMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
I IM+ L+ PN++ +E K + +V+E GELF+ ++ +G E A RQI
Sbjct: 122 IQIMQHLSGQPNIVEFKGAYEDEKAVNLVMELCAGGELFDRILAKGHYSERAAASVCRQI 181
Query: 136 IIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
+ ++ CH +G++HRDLKPEN LL D K +K DFG++ + ++ + GS +Y
Sbjct: 182 VNVVNICHFMGVMHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEGRVYKDIVGSAYYV 241
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGDD 251
APE++ +G E D+WS G+ILY LL+G PF E + I + +L+ + FE
Sbjct: 242 APEVLK--RRYGKEIDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGEI-DFESQPWP 298
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
IS+ A+DL+ R+LT DP++RI E+LKHP LR+
Sbjct: 299 SISNSAKDLVRRMLTQDPKRRISAAEVLKHPWLRE 333
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 152 bits (385), Expect = 2e-36
Identities = 90/284 (31%), Positives = 149/284 (51%), Gaps = 25/284 (8%)
Query: 10 KGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVL 69
K ++ ++LG LG G GKV + + G A+K++ K +++
Sbjct: 97 KSLSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKE---------------EII 141
Query: 70 PYGIE----REIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPE 125
Y ++ RE+ I LNHPN+ + Y + K +Y+++EY+ GE++ LL GP +
Sbjct: 142 KYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFND 201
Query: 126 NEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETS 185
A + QI + Y H I+HRD+KPEN+L+ +KL DFG + + + +T
Sbjct: 202 ILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTV 261
Query: 186 CGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKF 245
CG+ Y +PE+V Y D W+ GV+ + LLTG PF+EE + ++ +
Sbjct: 262 CGTIDYLSPEMVESREY-DHTIDAWALGVLAFELLTGAPPFEEEMKD--TTYKRIAALDI 318
Query: 246 EMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHP-LLRKYP 288
+MP + IS +AQDLI ++L DP+ R++ ++ HP +LR P
Sbjct: 319 KMPSN--ISQDAQDLILKLLKYDPKDRMRLGDVKMHPWILRNKP 360
>7296128 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 152 bits (385), Expect = 2e-36
Identities = 91/268 (33%), Positives = 148/268 (54%), Gaps = 22/268 (8%)
Query: 11 GDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIIS--KSIFNAQGSTMIGGNDPDV 68
G IG ++ +G G+ KV +A ++ + A+K++ ++ +A+ M+
Sbjct: 38 GRRIGLYRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKALRMLSS----- 92
Query: 69 LPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEA 128
EI ++ ++HPN+LRL++V ET +Y+V E++ GEL+N + + GPL E A
Sbjct: 93 -------EIATLECVHHPNILRLFEVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHA 145
Query: 129 VRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAAL----ESKDKLLET 184
+Q+++ + + H+LG VHRD+K EN+LL + +KLADFG + ++ L+T
Sbjct: 146 APLLKQLLLAVKHMHSLGYVHRDIKAENVLLLSEDRLKLADFGFSTQLINGTGANQKLDT 205
Query: 185 SCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGK 244
CGSP YAAPE+ S Y G DVW+ G++LY ++ G +PF I L + G
Sbjct: 206 FCGSPPYAAPELFSDDHYIGAPVDVWALGILLYFMVVGNMPF--RAPTIPGLKAAILKGD 263
Query: 245 FEMPGDDEISSEAQDLIARILTVDPEQR 272
+ +PG ++S LI RIL P QR
Sbjct: 264 YLLPG--QLSLPCIRLIQRILIHIPAQR 289
>SPAC890.03 [T] KOG0583 Serine/threonine protein kinase
Length = 672
Score = 152 bits (384), Expect = 3e-36
Identities = 93/275 (33%), Positives = 139/275 (49%), Gaps = 23/275 (8%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
+G +++ S +G GS GKV +A + K++ KS Q +
Sbjct: 28 VGTYRIESVVGEGSFGKVYLAAHLLTN----TKVVLKSSCRKQAIILA------------ 71
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
REI + L HPN+ RLY+V T +Y+ +EY GEL++ + L E R
Sbjct: 72 -REIHHHRRLLHPNITRLYEVVCTEDRIYLAMEYCPNGELYDWVAREKRLDEKTTCRIMW 130
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALE--SKDKLLETSCGSPHY 191
Q+ I Y H G VHRDLK EN+ LD +NVKL DFG + S+ + T CG+ Y
Sbjct: 131 QLCCAIQYLHRQGCVHRDLKLENIFLDKAYNVKLGDFGFSRDSDCSRRTFMNTRCGTVAY 190
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDD 251
APE+V G Y G D+WS G+I+YALL GRLPFDE+D ++ + + ++ +
Sbjct: 191 CAPELVQGHKYIGECVDIWSLGIIMYALLIGRLPFDEDDVSLTEQKIINECPQY----PE 246
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
+S + L+ +L D R +I+ HP ++
Sbjct: 247 TLSKNSSSLLKSLLCKDYRLRPSIDQIISHPYFKE 281
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 152 bits (384), Expect = 3e-36
Identities = 91/272 (33%), Positives = 145/272 (52%), Gaps = 22/272 (8%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+K+G T+G G+ V + ++ A+KII KS + + I+ E
Sbjct: 46 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK-------------EHMIQNE 92
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
+ I++ + HPN++ L + + +LY+V+E V+ G+LF+ + E +A +
Sbjct: 93 VSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLA 152
Query: 137 IGISYCHALGIVHRDLKPENLLL----DHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
I Y H+L IVHRD+KPENLL+ D ++KL DFG+A + D L T CG+P Y
Sbjct: 153 SAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATI--VDGPLYTVCGTPTYV 210
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD-- 250
APEI++ Y G + D+W+ GVI Y LL G PF + L ++ G+ + P
Sbjct: 211 APEIIAETGY-GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYW 269
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHP 282
D +S A++LI +L VD +QR ++L+HP
Sbjct: 270 DNVSDSAKELITMMLLVDVDQRFSAVQVLEHP 301
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 152 bits (383), Expect = 4e-36
Identities = 93/273 (34%), Positives = 144/273 (52%), Gaps = 13/273 (4%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+++G LG G V + G++ A K I K + + V IERE
Sbjct: 13 YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKR--------RLSSSRRGVSREEIERE 64
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
+ I++ + HPN++ L+D++E D+ ++LE V GELF+ L E+ L E+EA +F +QI+
Sbjct: 65 VNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQIL 124
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKF----NVKLADFGMAALESKDKLLETSCGSPHYA 192
G+ Y H+ I H DLKPEN++L K +KL DFG+A + G+P +
Sbjct: 125 DGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFV 184
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDE 252
APEIV+ P G E+D+WS GVI Y LL+G PF E + + F+
Sbjct: 185 APEIVNYEPL-GLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSN 243
Query: 253 ISSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
S A+D I R+L DP++R+ + L+H ++
Sbjct: 244 TSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIK 276
>Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 151 bits (382), Expect = 5e-36
Identities = 94/292 (32%), Positives = 157/292 (53%), Gaps = 27/292 (9%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ + + +G GS +VV +T + A+K++ + + + E
Sbjct: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACV--------------SE 108
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
+ +++ ++H +++L +++ET +YMV+E GELF+ L+ +G E +AVR + +
Sbjct: 109 LSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVA 168
Query: 137 IGISYCHALGIVHRDLKPENLLLDH---KFNVKLADFGMA--ALESKDKLLETSCGSPHY 191
GI Y HAL I HR+LKPENLL H + + + DFG+A +S D ++T CG+P Y
Sbjct: 169 DGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEY 228
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD- 250
APE++ PY D+W+ GVI YALL+G LPFD+E L K+ GK+ G+
Sbjct: 229 IAPEVLLRKPYTS-AVDMWALGVITYALLSGFLPFDDESQT--RLYRKILKGKYNYTGEP 285
Query: 251 -DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPR 301
IS A+D I ++L ++ R+ + L HP + ++ S++NL R
Sbjct: 286 WPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWV---ITMAAGSSMKNLQR 334
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 150 bits (378), Expect = 1e-35
Identities = 99/267 (37%), Positives = 141/267 (52%), Gaps = 17/267 (6%)
Query: 19 LGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREII 78
LG LG G G + + ++ G++ A K ISK Q I+ EI
Sbjct: 46 LGEQLGWGQFGVIRVCSDKLTGERLACKSISKDRLVTQDDMK-----------SIKLEIA 94
Query: 79 IM-KLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIII 137
IM KL HPNV+ L V+E +++V+E GELF+ L + G E A F+ ++
Sbjct: 95 IMAKLAGHPNVVNLKAVYEEKDSVHLVMELCAGGELFHKLEKYGRYSEVRARVLFKHLMQ 154
Query: 138 GISYCHALGIVHRDLKPENLL---LDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAP 194
+ +CH GIVHRDLKPEN+L + +KLADFG+A + L + GSP Y AP
Sbjct: 155 VVKFCHDSGIVHRDLKPENILMATMSSSSPIKLADFGLATYIKPGEKLSGTVGSPFYIAP 214
Query: 195 EIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEIS 254
E+++G + +DVWS GVILY LL+G PF + + ++ +F D I+
Sbjct: 215 EVLAG--GYNQAADVWSAGVILYILLSGAPPFWGKTKSKIFDAVRAADLRFSAEPWDNIT 272
Query: 255 SEAQDLIARILTVDPEQRIKTREILKH 281
S A+DLI +L VDP QR+ E+L H
Sbjct: 273 SYAKDLIRGMLCVDPSQRLSADEVLAH 299
>HsM8923212 [T] KOG4717 Serine/threonine protein kinase
Length = 244
Score = 149 bits (377), Expect = 2e-35
Identities = 94/251 (37%), Positives = 141/251 (55%), Gaps = 18/251 (7%)
Query: 11 GDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLP 70
G G + L TLG G V +A + G++ AVK+I K+ + T+ G+
Sbjct: 10 GKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLD----TLATGH------ 59
Query: 71 YGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGP-LPENEAV 129
+ +E+ MKL+ HPN++RLY+V +T LY++LE + G++F+ +++ L E+ A
Sbjct: 60 --LFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAK 117
Query: 130 RFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFN-VKLADFGMAALESKDKLLETSCGS 188
++F QI+ ISYCH L +VHRDLKPEN++ K VKL DFG + K L TSCGS
Sbjct: 118 KYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGS 177
Query: 189 PHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMP 248
Y+APEI+ G Y D+WS GVIL+ L+ + PF E N L + K+ +P
Sbjct: 178 LAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCEQPPFQE--ANDSETLTMIMDCKYTVP 235
Query: 249 GDDEISSEAQD 259
+S E ++
Sbjct: 236 --SHVSKECKE 244
>At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 583
Score = 149 bits (377), Expect = 2e-35
Identities = 94/274 (34%), Positives = 144/274 (52%), Gaps = 19/274 (6%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ +G LG G G + ++ G++ A K I+K + RE
Sbjct: 134 YSVGRKLGQGQFGTTFLCVDKKTGKEFACKTIAKRKLTTPEDVE-----------DVRRE 182
Query: 77 IIIMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
I IM L+ HPNV+++ +E + +++V+E GELF+ +++RG E +A R I
Sbjct: 183 IQIMHHLSGHPNVIQIVGAYEDAVAVHVVMEICAGGELFDRIIQRGHYTEKKAAELARII 242
Query: 136 IIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
+ I CH+LG++HRDLKPEN L D + +K DFG++ + GSP+Y
Sbjct: 243 VGVIEACHSLGVMHRDLKPENFLFVSGDEEAALKTIDFGLSVFFKPGETFTDVVGSPYYV 302
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGDD 251
APE++ ++ E DVWS GVI+Y LL+G PF DE + I +LK P
Sbjct: 303 APEVLR--KHYSHECDVWSAGVIIYILLSGVPPFWDETEQGIFEQVLKGDLDFISEPW-P 359
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
+S A+DL+ R+L DP++R+ T E+L HP R
Sbjct: 360 SVSESAKDLVRRMLIRDPKKRMTTHEVLCHPWAR 393
>At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 495
Score = 149 bits (376), Expect = 2e-35
Identities = 101/272 (37%), Positives = 143/272 (52%), Gaps = 25/272 (9%)
Query: 19 LGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREII 78
LG LG G G + ++ A K I K ++ D + + REI
Sbjct: 28 LGKKLGQGQFGTTYLCTEKSTSANYACKSIPKR-------KLVCREDYE----DVWREIQ 76
Query: 79 IMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIII 137
IM L+ HPNV+R+ +E S +++V+E E GELF+ +V +G E EAV+ + I+
Sbjct: 77 IMHHLSEHPNVVRIKGTYEDSVFVHIVMEVCEGGELFDRIVSKGHFSEREAVKLIKTILG 136
Query: 138 GISYCHALGIVHRDLKPENLLLD---HKFNVKLADFGMAALESKDKLLETSCGSPHYAAP 194
+ CH+LG++HRDLKPEN L D +K DFG++ + L GSP+Y AP
Sbjct: 137 VVEACHSLGVMHRDLKPENFLFDSPKDDAKLKATDFGLSVFYKPGQYLYDVVGSPYYVAP 196
Query: 195 EIVSGLPYHGFESDVWSCGVILYALLTGRLPF--DEEDGNIRNLLLKVQSGKFEMPGD-- 250
E++ +G E DVWS GVILY LL+G PF + E G R +L GK + D
Sbjct: 197 EVLK--KCYGPEIDVWSAGVILYILLSGVPPFWAETESGIFRQIL----QGKLDFKSDPW 250
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHP 282
IS A+DLI ++L P++RI E L HP
Sbjct: 251 PTISEAAKDLIYKMLERSPKKRISAHEALCHP 282
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 446
Score = 149 bits (375), Expect = 3e-35
Identities = 96/271 (35%), Positives = 148/271 (54%), Gaps = 21/271 (7%)
Query: 20 GSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIII 79
G TLG G+ G V A N G+ AVKI+ K GN + + E+ I
Sbjct: 40 GKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALK--------GNKVQL--EALYDELDI 89
Query: 80 MKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGI 139
++ L+HPN++ D +E+ Y++ + + GELF+ ++++G E +AVR +I+ +
Sbjct: 90 LQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAV 149
Query: 140 SYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMA-ALESKDKLLETSCGSPHYAAPE 195
Y H+ IVHRDLKPENLL K + + +ADFG+A L+S ++LL GS Y APE
Sbjct: 150 KYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPE 209
Query: 196 IVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSG----KFEMPGDD 251
+++ HG D+WS GVI Y LL G F E +++ L + +G KF P D
Sbjct: 210 VLT-QDGHGKPCDIWSIGVITYTLLCGYSAFRAE--RVQDFLDECTTGEYPVKFHRPYWD 266
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKHP 282
+S++A+ I + L +DP +R E+L+ P
Sbjct: 267 SVSNKAKQFILKALNLDPSKRPTAAELLEDP 297
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 148 bits (373), Expect = 5e-35
Identities = 86/275 (31%), Positives = 143/275 (51%), Gaps = 21/275 (7%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYG 72
TI +++G LG G G V +A + A+K++ KS +G + +
Sbjct: 73 TIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEG-----------VEHQ 121
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
+ REI I L+HPN+LRLY+ + + +Y++LEY +GEL+ L + E
Sbjct: 122 LRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIM 181
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
++ + YCH ++HRD+KPENLLL K +K+ADFG ++ + +T CG+ Y
Sbjct: 182 EELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGW-SVHAPSLRRKTMCGTLDYL 240
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGN--IRNLLLKVQSGKFEMPGD 250
PE++ G H + D+W GV+ Y LL G PF+ N R ++ K ++
Sbjct: 241 PPEMIEG-RMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIV------KVDLKFP 293
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
+ + AQDLI+++L +P +R+ ++ HP +R
Sbjct: 294 ASVPTGAQDLISKLLRHNPSERLPLAQVSAHPWVR 328
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 148 bits (373), Expect = 5e-35
Identities = 90/276 (32%), Positives = 146/276 (52%), Gaps = 19/276 (6%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYG 72
T+ +++G LG G G V +A + A+K++ KS +G L +
Sbjct: 5 TVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEG-----------LEHQ 53
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
+ REI I L HPN+LRLY+ + ++ +Y++LEY +GEL+ L + L E
Sbjct: 54 LRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATII 113
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
++ ++YCH ++HRD+KPENLLL + VK+ADFG ++ + +T CG+ Y
Sbjct: 114 EEVADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGW-SVHTPLPERKTMCGTLDYL 172
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDE-EDGNIRNLLLKVQSGKFEMPGDD 251
PE++ G Y + D+W GV+ Y LL G PF+ +LKV +F +
Sbjct: 173 PPEMIEGRTYDE-KVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDV-RFPL---- 226
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKHPLLRKY 287
+ A+DLI+R+L P +R+ +ILKHP ++ +
Sbjct: 227 SMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAH 262
>CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 357
Score = 148 bits (373), Expect = 5e-35
Identities = 102/302 (33%), Positives = 154/302 (50%), Gaps = 20/302 (6%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISK-------SIFNAQGSTMIGGND- 65
+ ++L +G GS G V +AYNE A+K++ K + F N
Sbjct: 18 LNQYRLMEEIGQGSYGIVKLAYNEEDKNLYALKVLDKMKLLKNFACFRQPPPRRNKENAA 77
Query: 66 PDVLPYG---IEREIIIMKLLNHPNVLRLYDVWETSKD--LYMVLEYVEKGELFNLLVER 120
P VL +++EI I+K L+HPNV++L +V + D LYMV E+VEKG + + ++
Sbjct: 78 PSVLRNPLQLVQKEIAILKKLSHPNVVKLVEVLDDPNDNYLYMVFEFVEKGSILEIPTDK 137
Query: 121 GPLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAA-LESKD 179
PL E+ A +FR + G+ Y H IVHRD+KP NLLL VK+ADFG++ E D
Sbjct: 138 -PLDEDTAWSYFRDTLCGLEYLHYQKIVHRDIKPSNLLLSDIGQVKIADFGVSCEFEGID 196
Query: 180 KLLETSCGSPHYAAPEIV---SGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNL 236
L + G+P + APE + + Y G D+WS G+ LYA + G +PF D I L
Sbjct: 197 AFLSGTAGTPAFMAPEALTEGANHFYSGRAQDIWSLGITLYAFVIGTVPF--VDNYIIAL 254
Query: 237 LLKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSI 296
K+++ P +S QD+I +L DP R+ E+ H + + ++ S
Sbjct: 255 HKKIKNDPIVFPEAPILSEALQDIILGMLKKDPGHRLMLHEVKVHTWVTRDGTVPMSSEQ 314
Query: 297 RN 298
N
Sbjct: 315 EN 316
>At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 610
Score = 148 bits (373), Expect = 5e-35
Identities = 95/272 (34%), Positives = 143/272 (51%), Gaps = 21/272 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ LG LG G G + +T G++ A K I+K D DV + RE
Sbjct: 150 YSLGRKLGQGQFGTTFLCVEKTTGKEFACKSIAKRKLLT---------DEDV--EDVRRE 198
Query: 77 IIIMK-LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
I IM L HPNV+ + +E +++V+E GELF+ +++RG E +A R I
Sbjct: 199 IQIMHHLAGHPNVISIKGAYEDVVAVHLVMECCAGGELFDRIIQRGHYTERKAAELTRTI 258
Query: 136 IIGISYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYA 192
+ + CH+LG++HRDLKPEN L K +K DFG++ D + GSP+Y
Sbjct: 259 VGVVEACHSLGVMHRDLKPENFLFVSKHEDSLLKTIDFGLSMFFKPDDVFTDVVGSPYYV 318
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD-- 250
APE++ +G E+DVWS GVI+Y LL+G PF E + + +V G + D
Sbjct: 319 APEVLR--KRYGPEADVWSAGVIVYILLSGVPPFWAE--TEQGIFEQVLHGDLDFSSDPW 374
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHP 282
IS A+DL+ ++L DP++R+ ++L HP
Sbjct: 375 PSISESAKDLVRKMLVRDPKKRLTAHQVLCHP 406
>At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 601
Score = 148 bits (373), Expect = 5e-35
Identities = 104/304 (34%), Positives = 154/304 (50%), Gaps = 23/304 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAY---NETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
++LG +G G G A + KGQQ AVK+I K A+ +T I D +
Sbjct: 148 YELGDEVGRGHFGYTCAAKFKKGDNKGQQVAVKVIPK----AKMTTAIAIED-------V 196
Query: 74 EREIIIMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERG-PLPENEAVRF 131
RE+ I++ L+ H N+ YD +E ++Y+V+E E GEL + ++ RG E +A
Sbjct: 197 RREVKILRALSGHNNLPHFYDAYEDHDNVYIVMELCEGGELLDRILSRGGKYTEEDAKTV 256
Query: 132 FRQIIIGISYCHALGIVHRDLKPENLLLDHK---FNVKLADFGMAALESKDKLLETSCGS 188
QI+ +++CH G+VHRDLKPEN L K +K DFG++ D+ L GS
Sbjct: 257 MIQILNVVAFCHLQGVVHRDLKPENFLFTSKEDTSQLKAIDFGLSDYVRPDERLNDIVGS 316
Query: 189 PHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEM 247
+Y APE++ + E+D+WS GVI+Y LL G PF + I +LK F+
Sbjct: 317 AYYVAPEVLH--RSYSTEADIWSVGVIVYILLCGSRPFWARTESGIFRAVLKADP-SFDD 373
Query: 248 PGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLN 307
P +SSEA+D + R+L DP +R+ + L HP ++ K I YL
Sbjct: 374 PPWPLLSSEARDFVKRLLNKDPRKRLTAAQALSHPWIKDSNDAKVPMDILVFKLMRAYLR 433
Query: 308 PLSL 311
SL
Sbjct: 434 SSSL 437
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 148 bits (373), Expect = 5e-35
Identities = 98/294 (33%), Positives = 151/294 (51%), Gaps = 33/294 (11%)
Query: 7 TTLKGDTIGP------------WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFN 54
+T G IGP + L LG G G +++ G++ A K ISK
Sbjct: 63 STSSGSQIGPILNRPMIDLSALYDLHKELGRGQFGITYKCTDKSNGREYACKSISKR--- 119
Query: 55 AQGSTMIGGNDPDVLPYGIEREIIIMK-LLNHPNVLRLYDVWETSKDLYMVLEYVEKGEL 113
+I D + + RE++I++ L PN++ +E +L++V+E GEL
Sbjct: 120 ----KLIRRKDIE----DVRREVMILQHLTGQPNIVEFRGAYEDKDNLHLVMELCSGGEL 171
Query: 114 FNLLVERGPLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADF 170
F+ ++++G E EA FRQI+ + CH +G+VHRDLKPEN LL + +K DF
Sbjct: 172 FDRIIKKGSYSEKEAANIFRQIVNVVHVCHFMGVVHRDLKPENFLLVSNEEDSPIKATDF 231
Query: 171 GMAALESKDKLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEED 230
G++ + K+ GS +Y APE++ +G E DVWS GV+LY LL+G PF E
Sbjct: 232 GLSVFIEEGKVYRDIVGSAYYVAPEVLH--RNYGKEIDVWSAGVMLYILLSGVPPFWGE- 288
Query: 231 GNIRNLLLKVQSGKFEMPGD--DEISSEAQDLIARILTVDPEQRIKTREILKHP 282
+ + + GK ++ IS A+DLI ++L DP++RI E L+HP
Sbjct: 289 -TEKTIFEAILEGKLDLETSPWPTISESAKDLIRKMLIRDPKKRITAAEALEHP 341
>At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 501
Score = 147 bits (372), Expect = 7e-35
Identities = 100/272 (36%), Positives = 143/272 (51%), Gaps = 25/272 (9%)
Query: 19 LGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREII 78
LG LG G G + ++ A K I K ++ D + + REI
Sbjct: 27 LGKKLGQGQFGTTYLCTEKSSSANYACKSIPKR-------KLVCREDYE----DVWREIQ 75
Query: 79 IMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIII 137
IM L+ HPNV+R+ +E S +++V+E E GELF+ +V +G E EA + + I+
Sbjct: 76 IMHHLSEHPNVVRIKGTYEDSVFVHIVMEVCEGGELFDRIVSKGCFSEREAAKLIKTILG 135
Query: 138 GISYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYAAP 194
+ CH+LG++HRDLKPEN L D + +K DFG++ + L GSP+Y AP
Sbjct: 136 VVEACHSLGVMHRDLKPENFLFDSPSDDAKLKATDFGLSVFYKPGQYLYDVVGSPYYVAP 195
Query: 195 EIVSGLPYHGFESDVWSCGVILYALLTGRLPF--DEEDGNIRNLLLKVQSGKFEMPGD-- 250
E++ +G E DVWS GVILY LL+G PF + E G R +L GK + D
Sbjct: 196 EVLK--KCYGPEIDVWSAGVILYILLSGVPPFWAETESGIFRQIL----QGKIDFKSDPW 249
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHP 282
IS A+DLI ++L P++RI E L HP
Sbjct: 250 PTISEGAKDLIYKMLDRSPKKRISAHEALCHP 281
>At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 606
Score = 147 bits (372), Expect = 7e-35
Identities = 101/279 (36%), Positives = 149/279 (53%), Gaps = 23/279 (8%)
Query: 18 KLGSTLGVGSTGKVVMAY---NETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIE 74
+LG +G G G A E KGQ AVKII KS + +T I D +
Sbjct: 151 ELGEEIGRGHFGYTCSAKFKKGELKGQVVAVKIIPKS----KMTTAIAIED-------VR 199
Query: 75 REIIIMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERG-PLPENEAVRFF 132
RE+ I++ L+ H N+++ YD +E + ++Y+ +E E GEL + ++ RG EN+A
Sbjct: 200 REVKILQALSGHKNLVQFYDAFEDNANVYIAMELCEGGELLDRILARGGKYSENDAKPVI 259
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHK---FNVKLADFGMAALESKDKLLETSCGSP 189
QI+ +++CH G+VHRDLKPEN L K +K DFG++ D+ L GS
Sbjct: 260 IQILNVVAFCHFQGVVHRDLKPENFLYTSKEENSQLKAIDFGLSDFVRPDERLNDIVGSA 319
Query: 190 HYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMP 248
+Y APE++ + E+DVWS GVI Y LL G PF + I +LK F+ P
Sbjct: 320 YYVAPEVLH--RSYTTEADVWSIGVIAYILLCGSRPFWARTESGIFRAVLKADP-SFDEP 376
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKY 287
+SS+A+D + R+L DP +R+ + L HP +R Y
Sbjct: 377 PWPFLSSDAKDFVKRLLFKDPRRRMSASQALMHPWIRAY 415
>Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 360
Score = 147 bits (372), Expect = 7e-35
Identities = 99/280 (35%), Positives = 145/280 (51%), Gaps = 23/280 (8%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
++L +G G V N GQQ AVKI+ + F + P + ++RE
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSS---------PGLSTEDLKRE 62
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPL----PENEAVRFF 132
I +L HP+++ L + + + LYMV E+++ +L +V+R E A +
Sbjct: 63 ASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYM 122
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETS-CGS 188
RQI+ + YCH I+HRD+KP +LL K N VKL FG+A + L+ G+
Sbjct: 123 RQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGT 182
Query: 189 PHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMP 248
PH+ APE+V PY G DVW CGVIL+ LL+G LPF G L + GK++M
Sbjct: 183 PHFMAPEVVKREPY-GKPVDVWGCGVILFILLSGCLPF---YGTKERLFEGIIKGKYKMN 238
Query: 249 GD--DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
IS A+DL+ R+L +DP +RI E L HP L++
Sbjct: 239 PRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKE 278
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 147 bits (371), Expect = 9e-35
Identities = 85/266 (31%), Positives = 138/266 (50%), Gaps = 17/266 (6%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+++G LG G G V +A + A+K++ K+ G + + + RE
Sbjct: 132 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAG-----------VEHQLRRE 180
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
+ I L HPN+LRLY + + +Y++LEY G ++ L + E + +I
Sbjct: 181 VEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTANLYNRIA 240
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEI 196
+SYCH+ ++HRD+KPENLLL +K+ADFG ++ + T CG+ Y PE+
Sbjct: 241 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW-SVHAPSSRRTTLCGTLDYLPPEM 299
Query: 197 VSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISSE 256
+ G H + D+WS GV+ Y L G+ PF E + ++ +F P D ++
Sbjct: 300 IEG-RMHDEKVDLWSLGVLCYEFLVGKPPF--EANTYQETYKRISRVEFTFP--DFVTEG 354
Query: 257 AQDLIARILTVDPEQRIKTREILKHP 282
A+DLI+R+L +P QR RE+L+HP
Sbjct: 355 ARDLISRLLKHNPSQRPMLREVLEHP 380
>At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 646
Score = 147 bits (370), Expect = 1e-34
Identities = 95/272 (34%), Positives = 142/272 (51%), Gaps = 21/272 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ LG LG G G + + G + A K ISK D DV + RE
Sbjct: 186 YSLGRKLGQGQFGTTFLCLEKGTGNEYACKSISKRKLLT---------DEDV--EDVRRE 234
Query: 77 IIIMK-LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
I IM L HPNV+ + +E +++V+E GELF+ +++RG E +A R I
Sbjct: 235 IQIMHHLAGHPNVISIKGAYEDVVAVHLVMELCSGGELFDRIIQRGHYTERKAAELARTI 294
Query: 136 IIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
+ + CH+LG++HRDLKPEN L + +K DFG++ D++ GSP+Y
Sbjct: 295 VGVLEACHSLGVMHRDLKPENFLFVSREEDSLLKTIDFGLSMFFKPDEVFTDVVGSPYYV 354
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD-- 250
APE++ +G ESDVWS GVI+Y LL+G PF E + + +V G + D
Sbjct: 355 APEVLR--KRYGPESDVWSAGVIVYILLSGVPPFWAE--TEQGIFEQVLHGDLDFSSDPW 410
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHP 282
IS A+DL+ ++L DP++R+ ++L HP
Sbjct: 411 PSISESAKDLVRKMLVRDPKRRLTAHQVLCHP 442
>YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 513
Score = 146 bits (369), Expect = 2e-34
Identities = 96/290 (33%), Positives = 146/290 (50%), Gaps = 39/290 (13%)
Query: 19 LGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREII 78
LG LG G V A N+ GQQ AVKI F+AQ ND E
Sbjct: 202 LGKELGAGHYALVKEAKNKKTGQQVAVKI-----FHAQQ------NDDQKKNKQFREETN 250
Query: 79 IMKLLNHPNVLRLYD-----VWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
I+ + HPN++ L D + ++ Y+VLE ++ GELF +V + L ++E+ F+
Sbjct: 251 ILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFK 310
Query: 134 QIIIGISYCHALGIVHRDLKPENLLL-------------------DHKFNVKLADFGMAA 174
Q++ G+ Y H I+HRD+KPEN+LL + VK+ADFG+A
Sbjct: 311 QLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAK 370
Query: 175 LESKDKLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDG--N 232
+ + T CG+P Y APE+++ Y + D+WS GVILY L G PF ++ G +
Sbjct: 371 FTGEMQFTNTLCGTPSYVAPEVLTKKGYTS-KVDLWSAGVILYVCLCGFPPFSDQLGPPS 429
Query: 233 IRNLLLKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHP 282
++ +L+ + F P D+I LI+ +L ++P++R E L HP
Sbjct: 430 LKEQILQAKYA-FYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHP 478
>At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 528
Score = 146 bits (369), Expect = 2e-34
Identities = 91/282 (32%), Positives = 146/282 (51%), Gaps = 23/282 (8%)
Query: 12 DTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPY 71
D + LG LG G G + + G Q A K I+K ++ D +
Sbjct: 68 DVKASYSLGKELGRGQFGVTHLCTQKATGHQFACKTIAKR-------KLVNKEDIE---- 116
Query: 72 GIEREIIIMK-LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVR 130
+ RE+ IM L PN++ L +E +++V+E GELF+ ++ +G E A
Sbjct: 117 DVRREVQIMHHLTGQPNIVELKGAYEDKHSVHLVMELCAGGELFDRIIAKGHYSERAAAS 176
Query: 131 FFRQIIIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCG 187
R I+ + CH++G++HRDLKPEN LL D +K DFG++ ++ + G
Sbjct: 177 LLRTIVQIVHTCHSMGVIHRDLKPENFLLLNKDENSPLKATDFGLSVFYKPGEVFKDIVG 236
Query: 188 SPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFE 246
S +Y APE++ +G E+D+WS GV+LY LL G PF E + I N +L+ G +
Sbjct: 237 SAYYIAPEVLK--RKYGPEADIWSIGVMLYILLCGVPPFWAESENGIFNAILR---GHVD 291
Query: 247 MPGD--DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
D IS +A+DL+ ++L DP+QR+ ++L HP +++
Sbjct: 292 FSSDPWPSISPQAKDLVKKMLNSDPKQRLTAAQVLNHPWIKE 333
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 146 bits (368), Expect = 2e-34
Identities = 84/266 (31%), Positives = 138/266 (51%), Gaps = 17/266 (6%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+++G LG G G V +A + A+K++ K+ G + + + RE
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAG-----------VEHQLRRE 181
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
+ I L HPN+LRLY + + +Y++LEY G ++ L + E + ++
Sbjct: 182 VEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELA 241
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEI 196
+SYCH+ ++HRD+KPENLLL +K+ADFG ++ + T CG+ Y PE+
Sbjct: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW-SVHAPSSRRTTLCGTLDYLPPEM 300
Query: 197 VSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISSE 256
+ G H + D+WS GV+ Y L G+ PF E + ++ +F P D ++
Sbjct: 301 IEG-RMHDEKVDLWSLGVLCYEFLVGKPPF--EANTYQETYKRISRVEFTFP--DFVTEG 355
Query: 257 AQDLIARILTVDPEQRIKTREILKHP 282
A+DLI+R+L +P QR RE+L+HP
Sbjct: 356 ARDLISRLLKHNPSQRPMLREVLEHP 381
>Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 501
Score = 146 bits (368), Expect = 2e-34
Identities = 81/219 (36%), Positives = 135/219 (60%), Gaps = 14/219 (6%)
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
+ EI I+K++ HPN+L+L DV+ T K+ ++ LE E+F+ ++++G E + R
Sbjct: 68 KNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVR 127
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKF---NVKLADFGMAALESKDKLLETSCGSPH 190
Q++ ++Y H+L IVHR+LK ENL+ ++ + ++DF +A LE + L++ CG+P
Sbjct: 128 QVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLE--NGLIKEPCGTPE 185
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEE------DGNIRNLLLKVQSG- 243
Y APE+V G +G D W+ GVI+Y LL+G PF EE + + +NL K+ +G
Sbjct: 186 YLAPEVV-GRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGD 244
Query: 244 -KFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKH 281
+F+ P D+IS A+DL+ R++ V+ +QRI E + H
Sbjct: 245 YEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISH 283
>At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 146 bits (368), Expect = 2e-34
Identities = 93/282 (32%), Positives = 147/282 (51%), Gaps = 23/282 (8%)
Query: 12 DTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPY 71
D + LG LG G G + + G Q A K I+K ++ D +
Sbjct: 63 DVKSSYTLGKELGRGQFGVTHLCTQKATGLQFACKTIAKR-------KLVNKEDIE---- 111
Query: 72 GIEREIIIMK-LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVR 130
+ RE+ IM L PN++ L +E +++V+E GELF+ ++ +G E A
Sbjct: 112 DVRREVQIMHHLTGQPNIVELKGAYEDKHSVHLVMELCAGGELFDRIIAKGHYSERAAAS 171
Query: 131 FFRQIIIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCG 187
R I+ I CH++G++HRDLKPEN LL D +K DFG++ ++ + G
Sbjct: 172 LLRTIVQIIHTCHSMGVIHRDLKPENFLLLSKDENSPLKATDFGLSVFYKPGEVFKDIVG 231
Query: 188 SPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFE 246
S +Y APE++ +G E+D+WS GV+LY LL G PF E + I N +L SG+ +
Sbjct: 232 SAYYIAPEVLR--RKYGPEADIWSIGVMLYILLCGVPPFWAESENGIFNAIL---SGQVD 286
Query: 247 MPGD--DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
D IS +A+DL+ ++L DP+QR+ ++L HP +++
Sbjct: 287 FSSDPWPVISPQAKDLVRKMLNSDPKQRLTAAQVLNHPWIKE 328
>At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 531
Score = 146 bits (368), Expect = 2e-34
Identities = 93/275 (33%), Positives = 145/275 (51%), Gaps = 21/275 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ LG LG G G M G A K I K +I D + ++RE
Sbjct: 80 YSLGKELGRGQFGITYMCKEIGTGNTYACKSILKR-------KLISKQDKE----DVKRE 128
Query: 77 IIIMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
I IM+ L+ PN++ + +E + +++V+E GELF+ ++ +G E A R I
Sbjct: 129 IQIMQYLSGQPNIVEIKGAYEDRQSIHLVMELCAGGELFDRIIAQGHYSERAAAGIIRSI 188
Query: 136 IIGISYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYA 192
+ + CH +G+VHRDLKPEN LL K +K DFG++ + K+ GS +Y
Sbjct: 189 VNVVQICHFMGVVHRDLKPENFLLSSKEENAMLKATDFGLSVFIEEGKVYRDIVGSAYYV 248
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD-- 250
APE++ +G E D+WS GVILY LL+G PF E N + + +V G+ + +
Sbjct: 249 APEVLR--RSYGKEIDIWSAGVILYILLSGVPPFWAE--NEKGIFDEVIKGEIDFVSEPW 304
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
IS A+DL+ ++LT DP++RI ++L+HP ++
Sbjct: 305 PSISESAKDLVRKMLTKDPKRRITAAQVLEHPWIK 339
>Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 145 bits (367), Expect = 3e-34
Identities = 95/272 (34%), Positives = 142/272 (51%), Gaps = 17/272 (6%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ +G LG G V ++ G + A K I K A V IERE
Sbjct: 23 YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRR--------GVSREEIERE 74
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
+ I++ + H NV+ L+DV+E D+ ++LE V GELF+ L ++ L E EA F +QI+
Sbjct: 75 VSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQIL 134
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKF----NVKLADFGMAALESKDKLLETSCGSPHYA 192
G++Y H I H DLKPEN++L K ++KL DFG+A + G+P +
Sbjct: 135 DGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFV 194
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPF--DEEDGNIRNLLLKVQSGKFEMPGD 250
APEIV+ P G E+D+WS GVI Y LL+G PF D + + N + S F+
Sbjct: 195 APEIVNYEPL-GLEADMWSIGVITYILLSGASPFLGDTKQETLAN--ITAVSYDFDEEFF 251
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHP 282
+ S A+D I ++L + +R+ +E L+HP
Sbjct: 252 SQTSELAKDFIRKLLVKETRKRLTIQEALRHP 283
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 145 bits (366), Expect = 3e-34
Identities = 90/280 (32%), Positives = 145/280 (51%), Gaps = 19/280 (6%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
IG +++G LG G G+V +A + G A+K + KS + +
Sbjct: 115 IGMFEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSK-----------IEKQV 163
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
REI I L H N+LRLY + K +Y++LE+ +GEL+ L E A ++
Sbjct: 164 RREIEIQSNLRHKNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIF 223
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAA 193
Q+ +SY H ++HRD+KPEN+LL +KL+DFG ++ + T CG+ Y
Sbjct: 224 QMANALSYLHKKHVIHRDIKPENILLGIDGEIKLSDFGW-SVHAPSNRRTTLCGTLDYLP 282
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE+V G H + D+WS GV+ Y L G PF++ G+ + K ++ +
Sbjct: 283 PEMVEG-KEHTEKVDLWSLGVLTYEFLVGAPPFEDMSGHSATY---KRIAKVDLKIPSFV 338
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDS 293
+A+DLI+R+L +PE+R+ ++++HP + KY KDS
Sbjct: 339 PPDARDLISRLLQHNPEKRMSLEQVMRHPWIVKY---KDS 375
>Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 992
Score = 145 bits (366), Expect = 3e-34
Identities = 82/227 (36%), Positives = 129/227 (56%), Gaps = 4/227 (1%)
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERG-PLPENEAVRF 131
I +EI IM L+HP +++ D +E ++ MVLE V GELF +++ L E E +++
Sbjct: 584 IRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKY 643
Query: 132 FRQIIIGISYCHALGIVHRDLKPENLLLDHK--FNVKLADFGMAALESKDKLLETSCGSP 189
RQI G+ Y H GIVH DLKPEN++ +K +KL DFG+A L+ G+P
Sbjct: 644 MRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTP 703
Query: 190 HYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPG 249
+ APE+++ P G+ +D+WS GVI Y L++G PF ++ N + + F+
Sbjct: 704 EFVAPEVINYEPI-GYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEA 762
Query: 250 DDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSI 296
DEIS +A+D I+ +L D + R+ + L+HP L K ++K +
Sbjct: 763 FDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKL 809
>Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1845
Score = 145 bits (366), Expect = 3e-34
Identities = 82/227 (36%), Positives = 129/227 (56%), Gaps = 4/227 (1%)
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERG-PLPENEAVRF 131
I +EI IM L+HP +++ D +E ++ MVLE V GELF +++ L E E +++
Sbjct: 1437 IRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKY 1496
Query: 132 FRQIIIGISYCHALGIVHRDLKPENLLLDHK--FNVKLADFGMAALESKDKLLETSCGSP 189
RQI G+ Y H GIVH DLKPEN++ +K +KL DFG+A L+ G+P
Sbjct: 1497 MRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTP 1556
Query: 190 HYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPG 249
+ APE+++ P G+ +D+WS GVI Y L++G PF ++ N + + F+
Sbjct: 1557 EFVAPEVINYEPI-GYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEA 1615
Query: 250 DDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSI 296
DEIS +A+D I+ +L D + R+ + L+HP L K ++K +
Sbjct: 1616 FDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKL 1662
>Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1914
Score = 145 bits (366), Expect = 3e-34
Identities = 82/227 (36%), Positives = 129/227 (56%), Gaps = 4/227 (1%)
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERG-PLPENEAVRF 131
I +EI IM L+HP +++ D +E ++ MVLE V GELF +++ L E E +++
Sbjct: 1506 IRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKY 1565
Query: 132 FRQIIIGISYCHALGIVHRDLKPENLLLDHK--FNVKLADFGMAALESKDKLLETSCGSP 189
RQI G+ Y H GIVH DLKPEN++ +K +KL DFG+A L+ G+P
Sbjct: 1566 MRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTP 1625
Query: 190 HYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPG 249
+ APE+++ P G+ +D+WS GVI Y L++G PF ++ N + + F+
Sbjct: 1626 EFVAPEVINYEPI-GYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEA 1684
Query: 250 DDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSI 296
DEIS +A+D I+ +L D + R+ + L+HP L K ++K +
Sbjct: 1685 FDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKL 1731
>Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 991
Score = 145 bits (366), Expect = 3e-34
Identities = 82/227 (36%), Positives = 129/227 (56%), Gaps = 4/227 (1%)
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERG-PLPENEAVRF 131
I +EI IM L+HP +++ D +E ++ MVLE V GELF +++ L E E +++
Sbjct: 584 IRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKY 643
Query: 132 FRQIIIGISYCHALGIVHRDLKPENLLLDHK--FNVKLADFGMAALESKDKLLETSCGSP 189
RQI G+ Y H GIVH DLKPEN++ +K +KL DFG+A L+ G+P
Sbjct: 644 MRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTP 703
Query: 190 HYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPG 249
+ APE+++ P G+ +D+WS GVI Y L++G PF ++ N + + F+
Sbjct: 704 EFVAPEVINYEPI-GYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEA 762
Query: 250 DDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSI 296
DEIS +A+D I+ +L D + R+ + L+HP L K ++K +
Sbjct: 763 FDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKL 809
>CE09360 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 2783
Score = 145 bits (366), Expect = 3e-34
Identities = 91/296 (30%), Positives = 151/296 (50%), Gaps = 22/296 (7%)
Query: 6 ITTLKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGND 65
I L D + + LG G+ G V A + G+ A K++
Sbjct: 184 IHRLPNDLQAKYIIHEELGKGAYGTVYRATEKATGKTWAAKMVQVR-------------- 229
Query: 66 PDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPE 125
P V + EI +M L+H +L L++ ++ +++++ E+V GELF ++E L
Sbjct: 230 PGVKKENVIHEISMMNQLHHEKLLNLHEAFDMGNEMWLIEEFVSGGELFEKILEDDSLMS 289
Query: 126 NEAVR-FFRQIIIGISYCHALGIVHRDLKPENLLLDHKFN--VKLADFGMAALESKDKLL 182
E VR + QI++G+S+ H IVH DLKPEN+LL K + +K+ DFG+A K +
Sbjct: 290 EEEVRDYMHQILLGVSHMHKNQIVHLDLKPENILLKAKNSNELKIIDFGLARKLDPKKSV 349
Query: 183 ETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF--DEEDGNIRNLLLKV 240
+ G+P + APE+V+ P G +D+W+ GVI Y LL+G PF D ++ + N +
Sbjct: 350 KLLFGTPEFCAPEVVNYQPV-GLSTDMWTVGVISYVLLSGLSPFLGDSDEDTLAN--VSA 406
Query: 241 QSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSI 296
F+ P D++S A+D I R++ D +R+ ++ L+HP + K D +
Sbjct: 407 SDWDFDDPSWDDVSDLAKDFICRLMIKDKRKRMSVQDALRHPWITKMQPKLDKSGV 462
>SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 652
Score = 145 bits (365), Expect = 5e-34
Identities = 96/282 (34%), Positives = 149/282 (52%), Gaps = 19/282 (6%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
I +++ LG G GKV + + + A+KII K+ + +G + +
Sbjct: 132 INHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKT----ERRPKLGRANASSQKEKV 187
Query: 74 EREIIIMKLLNHPNVLRLYDVWE--TSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRF 131
REI I+K HPNV+RL +V + +S +Y+VLEY+ GE+ + L +EA ++
Sbjct: 188 RREIAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQY 247
Query: 132 FRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAAL------ESKDKLLETS 185
FR +++G+ Y H GI+HRD+KP NLLL+ VK++DFG++ + E D L +
Sbjct: 248 FRDVVLGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIANAGLNEDNDVELAKT 307
Query: 186 CGSPHYAAPEIV-----SGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKV 240
G+P + APE+ P DVW+ GV L+ LL GR PF+ L K+
Sbjct: 308 VGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLFGRCPFNA--SMEYELFDKI 365
Query: 241 QSGKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHP 282
+ + +P +I E +DL+ R+L DPEQRI E+ HP
Sbjct: 366 VNERLNIPSTPDIGEEGRDLLKRLLCKDPEQRITLVEVKLHP 407
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 145 bits (365), Expect = 5e-34
Identities = 92/274 (33%), Positives = 147/274 (53%), Gaps = 26/274 (9%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+++ +GVGS ++ + AVKII KS DP E
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS-----------KRDPT------EEI 464
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I+++ HPN++ L DV++ K +Y+V E ++ GEL + ++ + E EA I
Sbjct: 465 EILLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTIT 524
Query: 137 IGISYCHALGIVHRDLKPENLL-LDHKFN---VKLADFGMA-ALESKDKLLETSCGSPHY 191
+ Y HA G+VHRDLKP N+L +D N +++ DFG A L +++ LL T C + ++
Sbjct: 525 KTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANF 584
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGD 250
APE++ Y D+WS GV+LY +LTG PF + D +L ++ SGKF + G
Sbjct: 585 VAPEVLKRQGYDA-ACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGG 643
Query: 251 --DEISSEAQDLIARILTVDPEQRIKTREILKHP 282
+ +S A+DL++++L VDP QR+ +L+HP
Sbjct: 644 YWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHP 677
Score = 129 bits (324), Expect = 3e-29
Identities = 83/263 (31%), Positives = 145/263 (54%), Gaps = 25/263 (9%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQA----AVKIISKSIFNAQGSTMIGGNDPDVLPYG 72
++L LG GS GKV + + G A A+K++ K+ + D +
Sbjct: 68 FELLKVLGQGSFGKVFLV-KKISGSDARQLYAMKVLKKATLKVR----------DRVRTK 116
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
+ER+I++ +NHP +++L+ ++T LY++L+++ G+LF L + E + +
Sbjct: 117 MERDILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYL 174
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKD--KLLETSCGSPH 190
++ + + + H+LGI++RDLKPEN+LLD + ++KL DFG++ ES D K + CG+
Sbjct: 175 AELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK-ESIDHEKKAYSFCGTVE 233
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
Y APE+V+ H +D WS GV+++ +LTG LPF +D + + + K MP
Sbjct: 234 YMAPEVVNRRG-HTQSADWWSFGVLMFEMLTGTLPFQGKDR--KETMTMILKAKLGMP-- 288
Query: 251 DEISSEAQDLIARILTVDPEQRI 273
+S EAQ L+ + +P R+
Sbjct: 289 QFLSPEAQSLLRMLFKRNPANRL 311
>At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 145 bits (365), Expect = 5e-34
Identities = 93/267 (34%), Positives = 146/267 (53%), Gaps = 22/267 (8%)
Query: 11 GDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLP 70
G +G + +G +G GS V A + G + A+K I+ N + L
Sbjct: 6 GRVVGDYLVGRQIGSGSFSVVWEARHRVDGTEVAIKEIAMDRLNKK------------LQ 53
Query: 71 YGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVR 130
+ EI I++ +NHPN++RL D+ ++ +++VLEY + G+L + G +PE A
Sbjct: 54 ESLMSEIFILRRINHPNIIRLIDMIKSPGKVHLVLEYCKGGDLSVYVQRHGIVPEATAKH 113
Query: 131 FFRQIIIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCG 187
F +Q+ G+ I+HRDLKP+NLLL ++ ++K+ADFG A L ET CG
Sbjct: 114 FMQQLAAGLQVLRDNNIIHRDLKPQNLLLSTNENDADLKIADFGFARSLQPRGLAETLCG 173
Query: 188 SPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLK--VQSGKF 245
SP Y APEI+ L + ++D+WS G IL+ L+TGR PF GN + LL+ ++S +
Sbjct: 174 SPLYMAPEIMQ-LQKYDAKADLWSVGAILFQLVTGRTPF---TGNSQIQLLQNIIRSTEL 229
Query: 246 EMPGD-DEISSEAQDLIARILTVDPEQ 271
PGD ++S + DL ++L +P Q
Sbjct: 230 HFPGDCRDLSLDCIDLCQKLLRRNPGQ 256
>Hs4507271 [T] KOG0583 Serine/threonine protein kinase
Length = 433
Score = 144 bits (364), Expect = 6e-34
Identities = 102/284 (35%), Positives = 150/284 (51%), Gaps = 29/284 (10%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYG- 72
IG + +G LG GS GKV + + AVKI+ K +P G
Sbjct: 46 IGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRR-------------IPNGE 92
Query: 73 --IEREIIIMKLLNHPNVLRLYDVW--ETSKDLYMVLEYVEKG--ELFNLLVERGPLPEN 126
+++EI +++ L H NV++L DV E + +YMV+EY G E+ + + E+ P
Sbjct: 93 ANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKR-FPVC 151
Query: 127 EAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMA-ALE--SKDKLLE 183
+A +F Q+I G+ Y H+ GIVH+D+KP NLLL +K++D G+A AL + D
Sbjct: 152 QAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCR 211
Query: 184 TSCGSPHYAAPEIVSGL-PYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQS 242
TS GSP + PEI +GL + GF+ D+WS GV LY + TG PF E NI L +
Sbjct: 212 TSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPF--EGDNIYKLFENIGK 269
Query: 243 GKFEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
G + +PGD DL+ +L +P +R R+I +H RK
Sbjct: 270 GSYAIPGD--CGPPLSDLLKGMLEYEPAKRFSIRQIRQHSWFRK 311
>7299793 [T] KOG0583 Serine/threonine protein kinase
Length = 540
Score = 144 bits (364), Expect = 6e-34
Identities = 123/433 (28%), Positives = 204/433 (46%), Gaps = 47/433 (10%)
Query: 14 IGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYG- 72
+G + +G LG GS GKV A N + AVKI++K +P G
Sbjct: 142 VGKYIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRKLRR-------------IPNGE 188
Query: 73 --IEREIIIMKLLNHPNVLRLYDVW--ETSKDLYMVLEYVEKGELFNLLVERGP---LPE 125
+ REI ++K L H +V+ L DV E + +Y+V+EY G +++ P +P
Sbjct: 189 QNVTREIALLKQLKHRHVVELVDVLYNEEKQKMYLVMEYCVGG--LQEMIDYQPDKRMPL 246
Query: 126 NEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAA---LESKDKLL 182
+A +F+Q++ G+ Y H+ ++H+D+KP NLLL +K++DFG+A L + D
Sbjct: 247 FQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQTLKISDFGVAEQLDLFAPDDTC 306
Query: 183 ETSCGSPHYAAPEIVSG-LPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQ 241
T GSP + PEI +G + GF+ D+WS GV LY L TG+ PF E NI LL +
Sbjct: 307 TTGQGSPAFQPPEIANGHETFAGFKVDIWSSGVTLYNLATGQYPF--EGDNIYRLLENIG 364
Query: 242 SGKFEMPG-DDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLP 300
G++E P E+ ++ +LI +L DP +R+ +EI R P +K I
Sbjct: 365 RGQWEAPAWLYEMDADFANLILGMLQADPSKRLSLQEIRHDTWFRSAP-VKTGPPI---- 419
Query: 301 REDTYLNPLSLEGGNQCVDETILQNLVVLWHGRNKEDIITKLMEPGANLEKTFYALLHRF 360
P+ G++ + T++ L +G +ED+ + L + A
Sbjct: 420 -------PIPPLKGDKYRNSTVIPYLEAYHYGTQEEDVYFTEHDVNQELARQAAAAASEI 472
Query: 361 KHDNYXXXXXXXXXXXXXSVSSNSLMYVGSLPSPNKSDSPVTTPKKKRTSIIVASSSHKR 420
+ S S+ + SL + ++ ++PV KKK +++ +
Sbjct: 473 RAKQSAAALAACHTYEPPSTSAAAAS--NSLGNGSREEAPV---KKKGSALKRRAKKLTS 527
Query: 421 PVSMQKLSSQHSS 433
+S++KLS +S
Sbjct: 528 CISVRKLSHCRTS 540
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 144 bits (363), Expect = 8e-34
Identities = 91/264 (34%), Positives = 145/264 (54%), Gaps = 30/264 (11%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG GS ++ Q VKIISK + + +T ++EI +KL
Sbjct: 432 LGEGSFSICRKCVHKKSNQALQVKIISKRM---EANT--------------QKEITALKL 474
Query: 83 LN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISY 141
HPN+++L++V+ ++V+E + GELF+ L ++ E EA R+++ +S+
Sbjct: 475 CEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSH 534
Query: 142 CHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKD-KLLETSCGSPHYAAPEIV 197
H LG+VHRDLKPENLL + +K+ DFG A L+ D + L+T C + H PE++
Sbjct: 535 MHDLGVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHSCRPELL 594
Query: 198 SGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIR-----NLLLKVQSGKFEMPGD-- 250
+ Y D+WS GVILY +L+G++PF D ++ ++ K++ G F G+
Sbjct: 595 NQNGYDE-SCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAW 653
Query: 251 DEISSEAQDLIARILTVDPEQRIK 274
+S EA+DLI +LTVDP +R+K
Sbjct: 654 KNVSQEAKDLIQGLLTVDPNKRLK 677
Score = 126 bits (317), Expect = 2e-28
Identities = 92/318 (28%), Positives = 155/318 (47%), Gaps = 35/318 (11%)
Query: 17 WKLGSTLGVGSTGKVVMAYN---ETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
++L LG G+ GKV + G+ A+K++ K+ + T
Sbjct: 49 FELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRT-------- 100
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
ER+++ + P ++ L+ ++T L+++L+Y+ GELF L +R E+E +
Sbjct: 101 ERQVL-EHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVG 159
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAA--LESKDKLLETSCGSPHY 191
+I++ + + H LGI++RD+K EN+LLD +V L DFG++ + + + + CG+ Y
Sbjct: 160 EIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEY 219
Query: 192 AAPEIV-SGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
AP+IV G H D WS GV++Y LLTG PF + + + K E P
Sbjct: 220 MAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYP 279
Query: 251 DEISSEAQDLIARILTVDPEQRI-----KTREILKHPLLRKY---------------PSI 290
E+S+ A+DLI R+L DP++R+ EI +H +K P I
Sbjct: 280 QEMSALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVI 339
Query: 291 KDSKSIRNLPREDTYLNP 308
+D + N E T ++P
Sbjct: 340 RDELDVSNFAEEFTEMDP 357
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 144 bits (363), Expect = 8e-34
Identities = 97/314 (30%), Positives = 161/314 (50%), Gaps = 35/314 (11%)
Query: 1 MNGNGITTLKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTM 60
++GN I G +++ +GVGS ++ + AVKII KS
Sbjct: 404 LHGNNIHFTDG-----YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKS--------- 449
Query: 61 IGGNDPDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVER 120
DP E I+++ HPN++ L DV++ K +Y+V+E + GEL + ++ +
Sbjct: 450 --KRDPS------EEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQ 501
Query: 121 GPLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKF----NVKLADFGMA-AL 175
E EA I + Y H+ G+VHRDLKP N+L + ++++ DFG A L
Sbjct: 502 RYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQL 561
Query: 176 ESKDKLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIR 234
+ + LL T C + ++ APE++ Y D+WS G++LY +L G PF + D
Sbjct: 562 RAGNGLLMTPCYTANFVAPEVLKRQGYDA-ACDIWSLGILLYTMLAGFTPFANGPDDTPE 620
Query: 235 NLLLKVQSGKFEMPGD--DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKD 292
+L ++ SGK+ + G D IS A+D+++++L VDP QR+ ++LKHP + ++
Sbjct: 621 EILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVN----RE 676
Query: 293 SKSIRNLPREDTYL 306
S L R+D +L
Sbjct: 677 YLSPNQLSRQDVHL 690
Score = 130 bits (328), Expect = 9e-30
Identities = 84/275 (30%), Positives = 146/275 (52%), Gaps = 26/275 (9%)
Query: 17 WKLGSTLGVGSTGKVVMAYN---ETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
++L LG GS GKV + GQ A+K++ K+ + D + +
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVR----------DRVRSKM 108
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
ER+I+ +NHP +++L+ ++T LY++L+++ G+LF L + E + +
Sbjct: 109 ERDILAE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLA 166
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMA-ALESKDKLLETSCGSPHYA 192
++ + + + H+LGI++RDLKPEN+LLD + ++K+ DFG++ DK + CG+ Y
Sbjct: 167 ELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYM 226
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDE 252
APE+V+ H +D WS GV+++ +LTG LPF +D + + + K MP
Sbjct: 227 APEVVNRRG-HTQSADWWSFGVLMFEMLTGSLPFQGKDR--KETMALILKAKLGMP--QF 281
Query: 253 ISSEAQDLIARILTVDPEQRI-----KTREILKHP 282
+S EAQ L+ + +P R+ EI +HP
Sbjct: 282 LSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHP 316
>At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 530
Score = 144 bits (363), Expect = 8e-34
Identities = 95/275 (34%), Positives = 145/275 (52%), Gaps = 21/275 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+KLG LG G G + G+ A K SI + T I D ++RE
Sbjct: 54 YKLGRELGRGEFGVTYLCTEIETGEIFACK----SILKKKLKTSIDIED-------VKRE 102
Query: 77 IIIMKLL-NHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
+ IM+ + HPN++ L + +E K +++V+E E GELF+ +V RG E A + I
Sbjct: 103 VEIMRQMPEHPNIVTLKETYEDDKAVHLVMELCEGGELFDRIVARGHYTERAAASVIKTI 162
Query: 136 IIGISYCHALGIVHRDLKPENLLLDHK---FNVKLADFGMAALESKDKLLETSCGSPHYA 192
I + CH G++HRDLKPEN L +K ++K DFG++ + GSP+Y
Sbjct: 163 IEVVQMCHKHGVMHRDLKPENFLFANKKETASLKAIDFGLSVFFKPGERFNEIVGSPYYM 222
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPF--DEEDGNIRNLLLKVQSGKFEMPGD 250
APE++ +G E D+WS GVILY LL G PF + E G + +L V F+
Sbjct: 223 APEVLR--RSYGQEIDIWSAGVILYILLCGVPPFWAETEHGVAKAILKSVID--FKRDPW 278
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
++S A+DLI ++L DP +R+ +++L HP ++
Sbjct: 279 PKVSDNAKDLIKKMLHPDPRRRLTAQQVLDHPWIQ 313
>7300413 [T] KOG0583 Serine/threonine protein kinase
Length = 302
Score = 144 bits (363), Expect = 8e-34
Identities = 90/276 (32%), Positives = 145/276 (51%), Gaps = 18/276 (6%)
Query: 17 WKLGSTLGVGSTGKVVMA-YNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIER 75
+ +G +G GS V+ A Y + G V + K I A+ T D + R
Sbjct: 28 YNVGHKIGEGSYATVITAGYADDHGH--GVHLACKIIDKAKAPT-------DFVNKFFPR 78
Query: 76 EIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
E+ I+ ++H N+++++ + + +++ + Y E G+L + + GP+ E ++ +F Q+
Sbjct: 79 ELEILTKIDHSNIIQIHSILQRGPKIFIFMRYAENGDLLSHIKRSGPIDEKQSKIWFFQM 138
Query: 136 IIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAAL----ESKDKLLETSCGSPHY 191
+ Y H L I HRDLK EN+LL + N+KLADFG A ++ ET CGS Y
Sbjct: 139 SKALKYLHNLDIAHRDLKCENILLSKRLNIKLADFGFARYCRDDNGREMKSETYCGSAAY 198
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPG-- 249
AAPE+V G PY +D WS GVIL+ ++ ++PFD D N+ LL ++ KF
Sbjct: 199 AAPEVVCGRPYDPKLADAWSLGVILFIMMNAKMPFD--DSNLTKLLEDQRNRKFAFRRKL 256
Query: 250 DDEISSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
+ IS++A+ ++ +L + R REIL LR
Sbjct: 257 QETISAQAKATVSVLLEPEAHARWNLREILNCAWLR 292
>At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 547
Score = 144 bits (362), Expect = 1e-33
Identities = 93/276 (33%), Positives = 142/276 (50%), Gaps = 20/276 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ LG LG G G + + G+ A K I K +I D + + RE
Sbjct: 98 YSLGRELGRGQFGITYICTEISSGKNFACKSILKR-------KLIRTKDRE----DVRRE 146
Query: 77 IIIMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
I IM L+ PN++ + +E + +++V+E E GELF+ + +RG E A R +
Sbjct: 147 IQIMHYLSGQPNIVEIKGAYEDRQSVHLVMELCEGGELFDKITKRGHYSEKAAAEIIRSV 206
Query: 136 IIGISYCHALGIVHRDLKPENLLLDHKFN----VKLADFGMAALESKDKLLETSCGSPHY 191
+ + CH +G++HRDLKPEN LL K +K DFG++ + K+ E GS +Y
Sbjct: 207 VKVVQICHFMGVIHRDLKPENFLLSSKDEASSMLKATDFGVSVFIEEGKVYEDIVGSAYY 266
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGD 250
APE++ +G D+WS GVILY LL G PF E D I +L+ + FE
Sbjct: 267 VAPEVLK--RNYGKAIDIWSAGVILYILLCGNPPFWAETDKGIFEEILRGEI-DFESEPW 323
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
IS A+DL+ +L DP++R ++L+HP +R+
Sbjct: 324 PSISESAKDLVRNMLKYDPKKRFTAAQVLEHPWIRE 359
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 143 bits (361), Expect = 1e-33
Identities = 90/283 (31%), Positives = 152/283 (52%), Gaps = 30/283 (10%)
Query: 22 TLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMK 81
T+GVGS + ++ + AVK+I KS DP E I+++
Sbjct: 423 TIGVGSYSECKRCVHKATNMEYAVKVIDKS-----------KRDPS------EEIEILLR 465
Query: 82 LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISY 141
HPN++ L DV++ K +Y+V E + GEL + ++ + E EA I + Y
Sbjct: 466 YGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEY 525
Query: 142 CHALGIVHRDLKPENLL-LDHKFN---VKLADFGMA-ALESKDKLLETSCGSPHYAAPEI 196
H+ G+VHRDLKP N+L +D N +++ DFG A L +++ LL T C + ++ APE+
Sbjct: 526 LHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEV 585
Query: 197 VSGLPYHGFES--DVWSCGVILYALLTGRLPFDEEDGNI-RNLLLKVQSGKFEMPGD--D 251
L G++ D+WS G++LY +L G PF + +L ++ SGKF + G +
Sbjct: 586 ---LKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWN 642
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSK 294
+S A+DL++++L VDP QR+ +++L+HP + + + S+
Sbjct: 643 TVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQ 685
Score = 135 bits (339), Expect = 5e-31
Identities = 86/263 (32%), Positives = 149/263 (55%), Gaps = 25/263 (9%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETK---GQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
++L LG GS GKV + T+ G A+K++ K+ + D + +
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVR----------DRVRTKM 111
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
ER+I+ +NHP V++L+ ++T LY++L+++ G+LF L + E + +
Sbjct: 112 ERDILAD--VNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLA 169
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMA--ALESKDKLLETSCGSPHY 191
++ +G+ + H+LGI++RDLKPEN+LLD + ++KL DFG++ A++ + K + CG+ Y
Sbjct: 170 ELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAY-SFCGTVEY 228
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEED-GNIRNLLLKVQSGKFEMPGD 250
APE+V+ H +D WS GV+++ +LTG LPF +D L+LK + G MP
Sbjct: 229 MAPEVVN-RQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLG---MP-- 282
Query: 251 DEISSEAQDLIARILTVDPEQRI 273
+S+EAQ L+ + +P R+
Sbjct: 283 QFLSTEAQSLLRALFKRNPANRL 305
>Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 456
Score = 143 bits (360), Expect = 2e-33
Identities = 95/297 (31%), Positives = 158/297 (52%), Gaps = 36/297 (12%)
Query: 5 GITTLKGDTIGPWKLGSTLGVGST----------GKVVMAYNETKGQQAAVKIISKSIFN 54
G T + + PWK T G +T G+V G + A KII
Sbjct: 152 GETGIPQHELAPWKPELTTGPHATPLPLFGRGRFGQVHKCEETATGLKLAAKIIKTR--- 208
Query: 55 AQGSTMIGGNDPDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELF 114
G D + ++ EI +M L+H N+++LYD +E+ D+ +V+EYV+ GELF
Sbjct: 209 -------GMKDKEE----VKNEISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGGELF 257
Query: 115 NLLVERG-PLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHK--FNVKLADFG 171
+ +++ L E + + F +QI GI + H + I+H DLKPEN+L ++ +K+ DFG
Sbjct: 258 DRIIDESYNLTELDTILFMKQICEGIRHMHQMYILHLDLKPENILCVNRDAKQIKIIDFG 317
Query: 172 MAALESKDKLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF--DEE 229
+A + L+ + G+P + APE+V+ + F +D+WS GVI Y LL+G PF D +
Sbjct: 318 LARRYKPREKLKVNFGTPEFLAPEVVN-YDFVSFPTDMWSVGVIAYMLLSGLSPFLGDND 376
Query: 230 DGNIRNLLLKVQSGKFEMPGDD--EISSEAQDLIARILTVDPEQRIKTREILKHPLL 284
+ N+L + ++++ ++ +IS EA++ I+++L + RI E LKHP L
Sbjct: 377 AETLNNIL----ACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALKHPWL 429
>At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 484
Score = 143 bits (360), Expect = 2e-33
Identities = 93/273 (34%), Positives = 147/273 (53%), Gaps = 23/273 (8%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ LG LG G G M + G++ A K I+K +I D + + RE
Sbjct: 24 YSLGHKLGQGQFGTTYMCKEISTGREYACKSITKR-------KLISKEDVE----DVRRE 72
Query: 77 IIIMK-LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
I IM L + N++ + +E +++V+E GELF+ +++RG E +A + I
Sbjct: 73 IQIMHHLAGYKNIVTIKGAYEDPLYVHIVMELCSGGELFDRIIQRGHYSERKAAELIKII 132
Query: 136 IIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
+ + CH+LG++HRDLKPEN LL D F++K DFG++ ++ E GSP+Y
Sbjct: 133 VGVVEACHSLGVMHRDLKPENFLLVNKDDDFSLKAIDFGLSVFFKPGQIFEDVVGSPYYV 192
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGD- 250
APE++ L ++G E+DVW+ GVILY L++G PF E I + +LK G + D
Sbjct: 193 APEVL--LKHYGPEADVWTAGVILYILVSGVPPFWAETQQGIFDAVLK---GHIDFDSDP 247
Query: 251 -DEISSEAQDLIARILTVDPEQRIKTREILKHP 282
IS A++LI +L P +R+ ++L+HP
Sbjct: 248 WPLISDSAKNLIRGMLCSRPSERLTAHQVLRHP 280
>At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 556
Score = 143 bits (360), Expect = 2e-33
Identities = 96/271 (35%), Positives = 143/271 (52%), Gaps = 19/271 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ L LG G G + G A K ISK +I D + + RE
Sbjct: 97 YTLSRKLGQGQFGTTYLCTEIASGVDYACKSISKR-------KLISKEDVE----DVRRE 145
Query: 77 IIIMK-LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
I IM L H +++ + +E S +++V+E GELF+ +++RG E +A + I
Sbjct: 146 IQIMHHLAGHGSIVTIKGAYEDSLYVHIVMELCAGGELFDRIIQRGHYSERKAAELTKII 205
Query: 136 IIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
+ + CH+LG++HRDLKPEN LL D F++K DFG++ ++ GSP+Y
Sbjct: 206 VGVVEACHSLGVMHRDLKPENFLLVNKDDDFSLKAIDFGLSVFFKPGQIFTDVVGSPYYV 265
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGDD 251
APE++ L +G E+DVW+ GVILY LL+G PF E I + +LK FE
Sbjct: 266 APEVL--LKRYGPEADVWTAGVILYILLSGVPPFWAETQQGIFDAVLKGYI-DFESDPWP 322
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKHP 282
IS A+DLI R+L+ P +R+ E+L+HP
Sbjct: 323 VISDSAKDLIRRMLSSKPAERLTAHEVLRHP 353
>At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 544
Score = 143 bits (360), Expect = 2e-33
Identities = 95/273 (34%), Positives = 144/273 (51%), Gaps = 23/273 (8%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ L LG G G + + G A K ISK +I D + + RE
Sbjct: 85 YTLSRKLGQGQFGTTYLCTDIATGVDYACKSISKR-------KLISKEDVE----DVRRE 133
Query: 77 IIIMK-LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
I IM L H N++ + +E +++V+E GELF+ ++ RG E +A + I
Sbjct: 134 IQIMHHLAGHKNIVTIKGAYEDPLYVHIVMELCAGGELFDRIIHRGHYSERKAAELTKII 193
Query: 136 IIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
+ + CH+LG++HRDLKPEN LL D F++K DFG++ ++ + GSP+Y
Sbjct: 194 VGVVEACHSLGVMHRDLKPENFLLVNKDDDFSLKAIDFGLSVFFKPGQIFKDVVGSPYYV 253
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGD- 250
APE++ L ++G E+DVW+ GVILY LL+G PF E I + +LK G + D
Sbjct: 254 APEVL--LKHYGPEADVWTAGVILYILLSGVPPFWAETQQGIFDAVLK---GYIDFDTDP 308
Query: 251 -DEISSEAQDLIARILTVDPEQRIKTREILKHP 282
IS A+DLI ++L P +R+ E+L+HP
Sbjct: 309 WPVISDSAKDLIRKMLCSSPSERLTAHEVLRHP 341
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 142 bits (359), Expect = 2e-33
Identities = 82/270 (30%), Positives = 148/270 (54%), Gaps = 23/270 (8%)
Query: 22 TLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMK 81
TLG GS G+V + + G+ A+K++ K I + + ND E +++
Sbjct: 92 TLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIV-VRLKQVEHTND----------ERLMLS 140
Query: 82 LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISY 141
++ HP ++R++ ++ ++ ++M+++Y+E GELF+LL + P A + ++ + + Y
Sbjct: 141 IVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEY 200
Query: 142 CHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEIVSGLP 201
H+ I++RDLKPEN+LLD ++K+ DFG A + + T CG+P Y APE+VS P
Sbjct: 201 LHSKDIIYRDLKPENILLDKNGHIKITDFGFA--KYVPDVTYTLCGTPDYIAPEVVSTKP 258
Query: 202 YHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISSEAQDLI 261
Y+ D WS G+++Y +L G PF D N K+ + + P + + +DL+
Sbjct: 259 YNK-SIDWWSFGILIYEMLAGYTPF--YDSNTMKTYEKILNAELRFP--PFFNEDVKDLL 313
Query: 262 ARILTVDPEQRI-----KTREILKHPLLRK 286
+R++T D QR+ T ++ HP ++
Sbjct: 314 SRLITRDLSQRLGNLQNGTEDVKNHPWFKE 343
>At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 599
Score = 142 bits (358), Expect = 3e-33
Identities = 102/303 (33%), Positives = 155/303 (50%), Gaps = 23/303 (7%)
Query: 18 KLGSTLGVGSTGKVVMAY---NETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIE 74
+LG +G G G A E K Q+ AVK+I KS + ++ I D +
Sbjct: 145 ELGEEIGRGHFGYTCSAKFKKGELKDQEVAVKVIPKS----KMTSAISIED-------VR 193
Query: 75 REIIIMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERG-PLPENEAVRFF 132
RE+ I++ L+ H N+++ YD +E + ++Y+V+E GEL + ++ RG E++A
Sbjct: 194 REVKILRALSGHQNLVQFYDAFEDNANVYIVMELCGGGELLDRILARGGKYSEDDAKAVL 253
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSP 189
QI+ +++CH G+VHRDLKPEN L K +K+ DFG++ D+ L GS
Sbjct: 254 IQILNVVAFCHLQGVVHRDLKPENFLYTSKEENSMLKVIDFGLSDFVRPDERLNDIVGSA 313
Query: 190 HYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMP 248
+Y APE++ + E+DVWS GVI Y LL G PF + I +LK F+ P
Sbjct: 314 YYVAPEVLH--RSYTTEADVWSIGVIAYILLCGSRPFWARTESGIFRAVLKADP-SFDEP 370
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDTYLNP 308
+S EA+D + R+L DP +R+ + L HP + Y I I + YL
Sbjct: 371 PWPSLSFEAKDFVKRLLYKDPRKRMTASQALMHPWIAGYKKIDIPFDILIFKQIKAYLRS 430
Query: 309 LSL 311
SL
Sbjct: 431 SSL 433
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 142 bits (357), Expect = 4e-33
Identities = 87/275 (31%), Positives = 150/275 (53%), Gaps = 23/275 (8%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYG 72
T+ +++ TLG GS G+V + + G+ A+K++ K + + ND
Sbjct: 66 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQV-VKMKQVEHTND------- 117
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
E ++KL+ HP ++R++ ++ +++++MV++Y+E GELF+LL + P A +
Sbjct: 118 ---ERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYA 174
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
++I+ + Y HA I++RDLKPEN+LLD ++K+ DFG A + + T CG+P Y
Sbjct: 175 AEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFA--KEVQTVTWTLCGTPDYI 232
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDE 252
APE+++ PY+ D WS GV++Y +L G PF D K+ GK P
Sbjct: 233 APEVITTKPYNK-SVDWWSLGVLIYEMLAGYTPF--YDTTPMKTYEKILQGKVVYP--PY 287
Query: 253 ISSEAQDLIARILTVDPEQRI-----KTREILKHP 282
+ DL+++++T D +RI +R+I HP
Sbjct: 288 FHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHP 322
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 142 bits (357), Expect = 4e-33
Identities = 91/269 (33%), Positives = 145/269 (53%), Gaps = 19/269 (7%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
+G GS G+V + Q A+K I K +G ++ ++ ++REI IM+
Sbjct: 10 IGEGSFGRVYKGRRKYSAQVVALKFIPK----------LGRSEKELR--NLQREIEIMRG 57
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L HPN++ + D +ET K++ +V +Y E GELF +L + G LPE++ Q++ + Y
Sbjct: 58 LRHPNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYL 116
Query: 143 HALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSC-GSPHYAAPEIVSGLP 201
H+ I+HRD+KP+N+LL +KL DFG A S + ++ TS G+P Y +PE+V P
Sbjct: 117 HSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERP 176
Query: 202 YHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISSEAQDLI 261
Y +D+WS G ILY L G PF +I L+ + P IS ++ +
Sbjct: 177 Y-DHTADLWSVGCILYELAVGTPPFYAT--SIFQLVSLILKDPVRWP--STISPCFKNFL 231
Query: 262 ARILTVDPEQRIKTREILKHPLLRKYPSI 290
+LT DP QR+ ++L HP + + +I
Sbjct: 232 QGLLTKDPRQRLSWPDLLYHPFIAGHVTI 260
>At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 407
Score = 142 bits (357), Expect = 4e-33
Identities = 92/277 (33%), Positives = 147/277 (52%), Gaps = 20/277 (7%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKS----IFNAQGSTMIGGNDPDV 68
TI + +G GS GKVV+ + GQ A+K KS + A T + DV
Sbjct: 105 TINEYVRVCKIGSGSYGKVVLYRSTLDGQYYAIKAFHKSHLLRLRVAPSETAMS----DV 160
Query: 69 LPYGIEREIIIMKLLNHPNVLRLYDVWETSKD--LYMVLEYVEKGELFNLLVERGPLPEN 126
L RE++IMK+L HPN++ L +V + + YMVLEYV+ +++ G L E
Sbjct: 161 L-----REVMIMKILEHPNIVNLIEVIDDPETDHFYMVLEYVDGKWVYDGSGPPGALGEK 215
Query: 127 EAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMA-ALESKDKLLETS 185
A ++ R I+ G+ Y HA ++H D+KP+NLL+ VK+ DF ++ + D L S
Sbjct: 216 TARKYLRDIVTGLMYLHAHDVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRS 275
Query: 186 CGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKF 245
G+P + APE G+ Y G +D W+ GV LY ++ G+ PF + +++ K+ +
Sbjct: 276 PGTPVFTAPECCLGITYSGRAADTWAVGVTLYCMILGQYPFLAD--TLQDTYDKIVNNPL 333
Query: 246 EMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHP 282
+P D ++ +DLI +L DP QR+ + + +HP
Sbjct: 334 IIP--DGLNPLLRDLIEGLLCKDPSQRMTLKNVSEHP 368
>At3g06030 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 651
Score = 142 bits (357), Expect = 4e-33
Identities = 84/290 (28%), Positives = 153/290 (51%), Gaps = 26/290 (8%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
W+ G +G G+ G+V M N G+ A+K + + +A G +E E
Sbjct: 68 WRKGELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRE------LEEE 121
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
+ ++K L+HPN++R S L +++E+V G + +LL + G PE + + +Q++
Sbjct: 122 VQLLKNLSHPNIVRYLGTVRESDSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLL 181
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSC--------GS 188
+G+ Y H GI+HRD+K N+L+D+K ++LADFG + K++E + G+
Sbjct: 182 LGLEYLHNNGIMHRDIKGANILVDNKGCIRLADFG-----ASKKVVELATVNGAKSMKGT 236
Query: 189 PHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMP 248
P++ APE++ H F +D+WS G + + TG+ P+ E+ +L + K P
Sbjct: 237 PYWMAPEVILQTG-HSFSADIWSVGCTVIEMATGKPPWSEQYQQFA-AVLHIGRTKAHPP 294
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREILKHPLL-----RKYPSIKDS 293
+++S EA+D + + L +P R+ E+L+HP + YP+ ++S
Sbjct: 295 IPEDLSPEAKDFLMKCLHKEPSLRLSATELLQHPFVTGKRQEPYPAYRNS 344
>At1g09000 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 666
Score = 142 bits (357), Expect = 4e-33
Identities = 82/272 (30%), Positives = 148/272 (54%), Gaps = 13/272 (4%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVK-IISKSIFNAQGSTMIGGNDPDVLPYGIER 75
W+ G +G G+ G V M N G+ AVK ++ + F ++ T + +E
Sbjct: 69 WRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQE-------LEE 121
Query: 76 EIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
E+ ++K L+HPN++R L ++LE+V G + +LL + GP PE+ + RQ+
Sbjct: 122 EVKLLKNLSHPNIVRYLGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQL 181
Query: 136 IIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLL---ETSCGSPHYA 192
++G+ Y H I+HRD+K N+L+D+K +KLADFG + ++ + ++ G+P++
Sbjct: 182 LLGLEYLHNHAIMHRDIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWM 241
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDE 252
APE++ H F +D+WS G + ++TG+ P+ ++ + + + + K P D
Sbjct: 242 APEVILQTG-HSFSADIWSVGCTVIEMVTGKAPWSQQYKEVAAIFF-IGTTKSHPPIPDT 299
Query: 253 ISSEAQDLIARILTVDPEQRIKTREILKHPLL 284
+SS+A+D + + L P R E+LKHP +
Sbjct: 300 LSSDAKDFLLKCLQEVPNLRPTASELLKHPFV 331
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 141 bits (356), Expect = 5e-33
Identities = 88/267 (32%), Positives = 142/267 (52%), Gaps = 21/267 (7%)
Query: 19 LGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREII 78
+G LG G G V +A + A+K++ K IG ++ + + + REI
Sbjct: 156 IGRLLGRGKFGNVYLAREKESQFVVALKVLFKR--------QIGESNVE---HQVRREIE 204
Query: 79 IMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLP---ENEAVRFFRQI 135
I L HP++LRLY + +Y++LEY +G LFN L + P+ E ++ + + +
Sbjct: 205 IQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNAL-QAQPMKRFDERQSATYIQAL 263
Query: 136 IIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPE 195
+ Y H I+HRD+KPENLLL HK +K+ADFG + E + + T CG+ Y PE
Sbjct: 264 CSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHE-PNSMRMTLCGTVDYLPPE 322
Query: 196 IVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISS 255
+V G P H D+WS GV+ + LL G PF + N K+ +++P + IS
Sbjct: 323 MVQGKP-HTKNVDLWSLGVLCFELLVGHAPFYSK--NYDETYKKILKVDYKLP--EHISK 377
Query: 256 EAQDLIARILTVDPEQRIKTREILKHP 282
A LI+++L ++P+ R+ +++ HP
Sbjct: 378 AASHLISKLLVLNPQHRLPLDQVMVHP 404
>At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 141 bits (355), Expect = 7e-33
Identities = 98/280 (35%), Positives = 147/280 (52%), Gaps = 23/280 (8%)
Query: 15 GPWKLGSTLGVGSTGKVVMAY---NETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPY 71
G ++LG +G G G A + KGQ AVKIISKS + S
Sbjct: 140 GKYELGREVGRGHFGHTCWAKAKKGKIKGQTVAVKIISKSKMTSALSIE----------- 188
Query: 72 GIEREIIIMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGP-LPENEAV 129
+ RE+ ++K L+ H ++++ YDV+E S ++++V+E E GEL + ++ RG PE EA
Sbjct: 189 DVRREVKLLKALSGHSHMVKFYDVFEDSDNVFVVMELCEGGELLDSILARGGRYPEAEAK 248
Query: 130 RFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSC 186
R QI+ ++ H G+VHRDLKPEN L K +K+ DFG++ D+ L
Sbjct: 249 RILVQILSATAFFHLQGVVHRDLKPENFLFTSKNEDAVLKVIDFGLSDYARFDQRLNDVV 308
Query: 187 GSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKF 245
GS +Y APE++ + E+D+WS GVI Y LL G PF + I +L+
Sbjct: 309 GSAYYVAPEVLH--RSYSTEADIWSIGVISYILLCGSRPFYGRTESAIFRCVLRANPNFD 366
Query: 246 EMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
++P IS A+D + R+L D +R+ + L HP LR
Sbjct: 367 DLPW-PSISPIAKDFVKRLLNKDHRKRMTAAQALAHPWLR 405
>At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 140 bits (354), Expect = 8e-33
Identities = 94/276 (34%), Positives = 145/276 (52%), Gaps = 23/276 (8%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ LG LG G G M G A K I K ++ +G D ++ E
Sbjct: 69 YSLGRELGRGGLGITYMCKEIGTGNIYACKSILKRKLISE----LGRED-------VKTE 117
Query: 77 IIIMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
I IM+ L+ PNV+ + +E +++V+E GELF+ ++ +G E A + I
Sbjct: 118 IQIMQHLSGQPNVVEIKGSYEDRHSVHLVMELCAGGELFDRIIAQGHYSERAAAGTIKSI 177
Query: 136 IIGISYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYA 192
+ + CH G++HRDLKPEN L K +K+ DFG++A + K+ + GSP+Y
Sbjct: 178 VDVVQICHLNGVIHRDLKPENFLFSSKEENAMLKVTDFGLSAFIEEGKIYKDVVGSPYYV 237
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPF--DEEDGNIRNLL-LKVQSGKFEMPG 249
APE++ +G E D+WS GVILY LL G PF D E+G +L K+ + P
Sbjct: 238 APEVLR--QSYGKEIDIWSAGVILYILLCGVPPFWADNEEGVFVEILKCKIDFVREPWP- 294
Query: 250 DDEISSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
IS A+DL+ ++LT DP++RI ++L+HP ++
Sbjct: 295 --SISDSAKDLVEKMLTEDPKRRITAAQVLEHPWIK 328
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 140 bits (353), Expect = 1e-32
Identities = 81/270 (30%), Positives = 136/270 (50%), Gaps = 16/270 (5%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYG 72
T+ + +G LG G G V +A + A+K++ KS + +
Sbjct: 27 TLSDFDIGKPLGRGKFGHVYLAREKRSNHVVALKVLFKSQLQQSQ-----------VEHQ 75
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
+ RE+ I L HPN+LRLY + K +Y++LEY +GEL+ L + E A +
Sbjct: 76 LRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKDLQKCKYFSERRAATYV 135
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
+ + YCH ++HRD+KPENLL+ + +K+ADFG + + T CG+ Y
Sbjct: 136 ASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFNRR--RTMCGTLDYL 193
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDE 252
PE+V + H D+WS G++ Y L G PF+ + + + ++ + P
Sbjct: 194 PPEMVESVE-HDASVDIWSLGILCYEFLYGVPPFEAMEHS--DTYRRIVQVDLKFPPKPI 250
Query: 253 ISSEAQDLIARILTVDPEQRIKTREILKHP 282
IS+ A+DLI+++L + QR+ ++L+HP
Sbjct: 251 ISASAKDLISQMLVKESSQRLPLHKLLEHP 280
>At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 140 bits (353), Expect = 1e-32
Identities = 90/252 (35%), Positives = 139/252 (54%), Gaps = 20/252 (7%)
Query: 39 KGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKLLN-HPNVLRLYDVWET 97
KGQ+ AVK+I KS + +T I D + RE+ +++ L H N+++ YD +E
Sbjct: 148 KGQEVAVKVIPKS----KMTTAIAIED-------VSREVKMLRALTGHKNLVQFYDAFED 196
Query: 98 SKDLYMVLEYVEKGELFNLLVERG-PLPENEAVRFFRQIIIGISYCHALGIVHRDLKPEN 156
+++Y+V+E + GEL + +++RG E++A + QI+ ++YCH G+VHRDLKPEN
Sbjct: 197 DENVYIVMELCKGGELLDKILQRGGKYSEDDAKKVMVQILSVVAYCHLQGVVHRDLKPEN 256
Query: 157 LLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCG 213
L D +K DFG++ D+ L GS +Y APE++ +G E+D+WS G
Sbjct: 257 FLFSTKDETSPLKAIDFGLSDYVKPDERLNDIVGSAYYVAPEVLHRT--YGTEADMWSIG 314
Query: 214 VILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQR 272
VI Y LL G PF + I +LK + E P +S EA D + R+L D +R
Sbjct: 315 VIAYILLCGSRPFWARTESGIFRAVLKAEPNFEEAPW-PSLSPEAVDFVKRLLNKDYRKR 373
Query: 273 IKTREILKHPLL 284
+ + L HP L
Sbjct: 374 LTAAQALCHPWL 385
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 140 bits (352), Expect = 1e-32
Identities = 93/309 (30%), Positives = 158/309 (51%), Gaps = 28/309 (9%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ G LG GS G V+ A ++ + A+K ++K + ++ ERE
Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLL------------ERE 163
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
+ I+K + H +++ L V+ET K +Y+V+E E GEL +L +G ENE + +
Sbjct: 164 VNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLA 223
Query: 137 IGISYCHALGIVHRDLKPENLLL---------DHKFNVKLADFGMAALES--KDKLLETS 185
I+Y H IVHRDLK EN+++ + N+K+ DFG+A + + +L+ +
Sbjct: 224 SAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQAT 283
Query: 186 CGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKF 245
CG+P Y APE++S Y + D+WS GV++Y LL G PF L++ F
Sbjct: 284 CGTPIYMAPEVISAHDY-SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHF 342
Query: 246 EMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLL--RKYPSIKDSKSIRNLPRED 303
E + IS A+ ++ +++ VDP RI +E+L + L K S++ + + + ++
Sbjct: 343 ENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMM--KE 400
Query: 304 TYLNPLSLE 312
NP S+E
Sbjct: 401 WKNNPESVE 409
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 139 bits (351), Expect = 2e-32
Identities = 92/290 (31%), Positives = 149/290 (50%), Gaps = 26/290 (8%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
++L +GVGS + T + AVKII KS DP E
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKS-----------KRDPS------EEI 468
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I+M+ HPN++ L DV++ + +Y+V + ++ GEL + ++++ E EA I
Sbjct: 469 EILMRYGQHPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVIS 528
Query: 137 IGISYCHALGIVHRDLKPENLL-LDHKF---NVKLADFGMA-ALESKDKLLETSCGSPHY 191
+ Y H G+VHRDLKP N+L +D ++++ DFG A L ++ LL T C + ++
Sbjct: 529 KTVDYLHCQGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANF 588
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGD 250
APE++ Y D+WS GV+ Y +L G PF + + +LL++ +GKF + G
Sbjct: 589 VAPEVLMQQGYDA-ACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGG 647
Query: 251 --DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRN 298
D IS A+DL++ +L +DP QR +ILKH + + + + RN
Sbjct: 648 NWDNISDGAKDLLSHMLHMDPHQRYTAEQILKHSWITHRDQLPNDQPKRN 697
Score = 137 bits (344), Expect = 1e-31
Identities = 88/273 (32%), Positives = 153/273 (55%), Gaps = 26/273 (9%)
Query: 17 WKLGSTLGVGSTGKVVMAYNET---KGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
++L LG GS GKV + +T GQ A+K++ K+ + D + +
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVR----------DRVRTKM 122
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
ER+I++ +NHP +++L+ ++T LY++L+++ G++F L + E + +
Sbjct: 123 ERDILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLA 180
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALE-SKDKLLETSCGSPHYA 192
++ + + + H LGIV+RDLKPEN+LLD ++KL DFG++ ++K + CG+ Y
Sbjct: 181 ELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYM 240
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGN-IRNLLLKVQSGKFEMPGDD 251
APE+V+ H +D WS GV+++ +LTG LPF +D N N++LK + G MP
Sbjct: 241 APEVVNRRG-HSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLG---MP--Q 294
Query: 252 EISSEAQDLIARILTVDPEQRIKT---REILKH 281
+S+EAQ L+ + +P R+ + EI +H
Sbjct: 295 FLSAEAQSLLRMLFKRNPANRLGSEGVEEIKRH 327
>Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 795
Score = 139 bits (351), Expect = 2e-32
Identities = 96/278 (34%), Positives = 149/278 (53%), Gaps = 23/278 (8%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIIS-KSIFNAQGSTMIGGNDPDVLPYGIEREIIIMK 81
LG G G+V ++ G A KII KS + + ++ EI IM
Sbjct: 497 LGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDRED---------------VKNEINIMN 541
Query: 82 LLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLV-ERGPLPENEAVRFFRQIIIGIS 140
L+H N+++LYD +E+ +V+EYV+ GELF+ + E+ L E + V F RQI G+
Sbjct: 542 QLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVH 601
Query: 141 YCHALGIVHRDLKPENLLLDHK--FNVKLADFGMAALESKDKLLETSCGSPHYAAPEIVS 198
Y H I+H DLKPEN+L ++ +K+ DFG+A + L+ + G+P + APE+V+
Sbjct: 602 YLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVN 661
Query: 199 GLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGDDEISSEA 257
+ F +D+WS GVI Y LL+G PF E D N ++ S F+ + +S EA
Sbjct: 662 -YEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNC-SWDFDADTFEGLSEEA 719
Query: 258 QDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKS 295
+D ++R+L + R+ + LKH L P+ K S+S
Sbjct: 720 KDFVSRLLVKEKSCRMSATQCLKHEWLNNLPA-KASRS 756
>CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 336
Score = 139 bits (351), Expect = 2e-32
Identities = 80/275 (29%), Positives = 142/275 (51%), Gaps = 7/275 (2%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSI----FNAQGSTMIGGNDPDVLPYG 72
+++G+ +G G+ V + + G + A+K+ +S F ++ + +
Sbjct: 57 YEIGAIIGKGNFSSVHLTRRKEDGTKCALKVRYQSTLQFSFPSKFFQQVEKRAMRGKCFF 116
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
++ E+ ++ L+ H +++ + D + T ++V E+ + G+L+ + + G + E +A
Sbjct: 117 VDNEVEMLSLIQHDHIISIIDAFSTENQYFIVFEHAQYGDLYETIRKNGRIEEPDAAIIT 176
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
Q+ ++Y H +VHRD+KPENLLL KF+VKL DFG+A L CG+P Y
Sbjct: 177 LQVASALNYLHERNVVHRDVKPENLLLVDKFSVKLCDFGLACHILGP--LYRICGTPTYC 234
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDE 252
APE++ Y D+WS GV+LY +L G PF D L+ +MP
Sbjct: 235 APEVLRETGY-STRCDIWSLGVVLYVMLVGYAPFRAPDQTRLFKLIMQAKPNLDMPEWKG 293
Query: 253 ISSEAQDLIARILTVDPEQRIKTREILKHPLLRKY 287
IS +A+DL++R++ E+R +I+ HP + Y
Sbjct: 294 ISLKAKDLVSRLMNKTEERRPLASQIMAHPWIAPY 328
>At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 382
Score = 139 bits (351), Expect = 2e-32
Identities = 90/276 (32%), Positives = 145/276 (51%), Gaps = 21/276 (7%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFN----AQGSTMIGGNDPDV 68
TI + +G GS GKVV+ + + A+K KS + A T +G DV
Sbjct: 93 TINEFVRERKIGSGSYGKVVLYRSTVDDKHYAIKAFHKSHLSRLRVAPSETAMG----DV 148
Query: 69 LPYGIEREIIIMKLLNHPNVLRLYDVWETSK--DLYMVLEYVEKGELFNLLVERGPLPEN 126
L RE++IMK L HPN++ L +V + + D YMVLEYV+ ++ G L E
Sbjct: 149 L-----REVMIMKTLEHPNIVNLIEVIDDPEFDDFYMVLEYVDGKWAYDDSGPPGALGEI 203
Query: 127 EAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSC 186
A ++ R ++ G+ Y HA ++H D+KP+NLL+ VK+ DF ++ + D L S
Sbjct: 204 TARKYLRDVVAGLMYLHAHNVIHGDIKPDNLLVTSTGRVKIGDFSVS--QDDDDQLRRSP 261
Query: 187 GSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFE 246
G+P + APE G+ Y G +D W+ GV LY ++ G+ PF + +++ K+
Sbjct: 262 GTPVFTAPECCLGITYSGRSADTWAVGVTLYCMILGQYPFLGD--TLQDTYDKIVHNPLI 319
Query: 247 MPGDDEISSEAQDLIARILTVDPEQRIKTREILKHP 282
+P + ++ +DLI +L DP QR+ + + +HP
Sbjct: 320 IP--EGLNPRLRDLIEGLLCKDPNQRMTLKAVAEHP 353
>At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 139 bits (350), Expect = 2e-32
Identities = 94/302 (31%), Positives = 156/302 (51%), Gaps = 24/302 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ LG +G G G + + G++ A K ISK T + D + RE
Sbjct: 57 YDLGREVGRGEFGITYLCTDIKTGEKYACKSISKKKLR----TAVDIED-------VRRE 105
Query: 77 IIIMKLL-NHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
+ IMK + HPN++ L D +E +++V+E E GELF+ +V RG E A + I
Sbjct: 106 VEIMKHMPRHPNIVSLKDAFEDDDAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTI 165
Query: 136 IIGISYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYA 192
+ + CH G++HRDLKPEN L +K +K DFG++ + GSP+Y
Sbjct: 166 LEVVQICHKHGVMHRDLKPENFLFANKKETSALKAIDFGLSVFFKPGEGFNEIVGSPYYM 225
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPF--DEEDGNIRNLLLKVQSGKFEMPGD 250
APE++ +G E D+WS GVILY LL G PF + E G + ++ V F+
Sbjct: 226 APEVLR--RNYGPEVDIWSAGVILYILLCGVPPFWAETEQGVAQAIIRSVID--FKRDPW 281
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLL---RKYPSIKDSKSIRNLPREDTYLN 307
+S A+DL+ ++L DP++R+ ++L+H + +K P++ ++++ ++ + +N
Sbjct: 282 PRVSETAKDLVRKMLEPDPKKRLSAAQVLEHSWIQNAKKAPNVSLGETVKARLKQFSVMN 341
Query: 308 PL 309
L
Sbjct: 342 KL 343
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 139 bits (350), Expect = 2e-32
Identities = 87/272 (31%), Positives = 142/272 (51%), Gaps = 29/272 (10%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYG 72
T ++LG GVGS KVV A + G A+KI+ K + T
Sbjct: 38 TYHDFELGKIYGVGSYSKVVRAKKKDNGTVYALKIMDKKFITKENKTAY----------- 86
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
++ E I++ L HP +++L+ ++ ++ LYM LE E GELF+ + +G L E+EA +
Sbjct: 87 VKLERIVLDQLEHPGIVKLFFTFQDTQSLYMALESCEGGELFDQITRKGRLSEDEARFYS 146
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFG------------MAALESKDK 180
+++ + Y H +G++HRD+KPENLLL ++K+ADFG + S DK
Sbjct: 147 AEVVDALEYIHNMGLIHRDIKPENLLLTLDGHIKIADFGSVKPMQDSQITVLPNAASDDK 206
Query: 181 LLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKV 240
T G+ Y PE+++ P F +D+W+ G LY +L+G PF +D + + ++
Sbjct: 207 AC-TFVGTAAYVPPEVLNSSP-ATFGNDLWALGCTLYQMLSGTSPF--KDASEWLIFQRI 262
Query: 241 QSGKFEMPGDDEISSEAQDLIARILTVDPEQR 272
+ + P + S A+DLI R+L DP +R
Sbjct: 263 IARDIKFP--NHFSEAARDLIDRLLDTDPSRR 292
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 139 bits (349), Expect = 3e-32
Identities = 92/275 (33%), Positives = 137/275 (49%), Gaps = 21/275 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+++G LG G+ V A + + A KI++K + + ++ E
Sbjct: 31 YRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDF-------------VKNE 77
Query: 77 IIIMKLLN--HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQ 134
I I+K ++ HPN+L L D +ET +LY++ E GELF+ + +G E +A R
Sbjct: 78 IAILKRVSYEHPNILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRT 137
Query: 135 IIIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAAL--ESKDKLLETSCGSP 189
+ Y H GIVHRDLKPENLL D ++ +ADFG++ +S+ +L T+CG+P
Sbjct: 138 TTSAVKYLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYEDSQYYMLMTACGTP 197
Query: 190 HYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPG 249
Y APE+ Y G D+W+ GVI Y LL+G PF + F P
Sbjct: 198 EYMAPEVFRRTGY-GKPVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILANEYTFNDPC 256
Query: 250 DDEISSEAQDLIARILTVDPEQRIKTREILKHPLL 284
IS A+D I + L DP +R+ + LKHP L
Sbjct: 257 WSGISETAKDFIKKCLENDPSKRLTAADALKHPFL 291
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 139 bits (349), Expect = 3e-32
Identities = 87/260 (33%), Positives = 140/260 (53%), Gaps = 32/260 (12%)
Query: 21 STLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREI--- 77
+T+G G+ G+V + +T A+K++S PDV+ E+ +
Sbjct: 53 ATVGTGTFGRVHLVKEKTAKHFFALKVMSI---------------PDVIRLKQEQHVHNE 97
Query: 78 -IIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
++K ++HP ++RL+ W + LYM++EYV GELF+ L RG + + +II
Sbjct: 98 KSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEII 157
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLE---TSCGSPHYAA 193
I Y H+ IV+RDLKPEN+LLD ++KL DFG A KL++ T CG+P Y A
Sbjct: 158 CAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFA-----KKLVDRTWTLCGTPEYLA 212
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PE++ HG D W+ G++++ +L+G PF D N + K+ +GK + P +
Sbjct: 213 PEVIQS-KGHGRAVDWWALGILIFEMLSGFPPF--FDDNPFGIYQKILAGKIDFP--RHL 267
Query: 254 SSEAQDLIARILTVDPEQRI 273
+DLI ++L VD +R+
Sbjct: 268 DFHVKDLIKKLLVVDRTRRL 287
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 139 bits (349), Expect = 3e-32
Identities = 85/268 (31%), Positives = 140/268 (51%), Gaps = 29/268 (10%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
++ G GVGS KVV A + G A+KI+ K + T ++ E
Sbjct: 41 FEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAY-----------VKLE 89
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I++ L HP +++LY ++ + LYM LE E GELF+ + +G L E+EA + +++
Sbjct: 90 RIVLDQLEHPGIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTAEVV 149
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFG------------MAALESKDKLLET 184
+ Y H++G++HRD+KPENLLL ++K+ADFG + S DK T
Sbjct: 150 DALEYIHSMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITVLPNAASDDKAC-T 208
Query: 185 SCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGK 244
G+ Y PE+++ P F +D+W+ G LY +L+G PF +D + + ++ +
Sbjct: 209 FVGTAAYVPPEVLNSSP-ATFGNDLWALGCTLYQMLSGTSPF--KDASEWLIFQRIIARD 265
Query: 245 FEMPGDDEISSEAQDLIARILTVDPEQR 272
+ P + S A+DLI R+L +P +R
Sbjct: 266 IKFP--NHFSEAARDLIDRLLDTEPSRR 291
>At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 577
Score = 139 bits (349), Expect = 3e-32
Identities = 90/252 (35%), Positives = 137/252 (53%), Gaps = 20/252 (7%)
Query: 39 KGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKLLN-HPNVLRLYDVWET 97
KGQ AVK+I KS + +T I D + RE+ I++ L H N+++ YD +E
Sbjct: 149 KGQDVAVKVIPKS----KMTTAIAIED-------VRREVKILRALTGHKNLVQFYDAFED 197
Query: 98 SKDLYMVLEYVEKGELFNLLVERG-PLPENEAVRFFRQIIIGISYCHALGIVHRDLKPEN 156
+++Y+V+E + GEL + +++RG E +A + QI+ ++YCH G+VHRDLKPEN
Sbjct: 198 DENVYIVMELCQGGELLDKILQRGGKYSEVDAKKVMIQILSVVAYCHLQGVVHRDLKPEN 257
Query: 157 LLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCG 213
L D +K DFG++ D+ L GS +Y APE++ +G E+D+WS G
Sbjct: 258 FLFTTKDESSPLKAIDFGLSDYVRPDERLNDIVGSAYYVAPEVLHRT--YGTEADMWSIG 315
Query: 214 VILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQR 272
VI Y LL G PF + I +LK + E P +S +A D + R+L D +R
Sbjct: 316 VIAYILLCGSRPFWARSESGIFRAVLKAEPNFEEAPW-PSLSPDAVDFVKRLLNKDYRKR 374
Query: 273 IKTREILKHPLL 284
+ + L HP L
Sbjct: 375 LTAAQALCHPWL 386
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 138 bits (348), Expect = 4e-32
Identities = 72/210 (34%), Positives = 127/210 (60%), Gaps = 6/210 (2%)
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
I++EI + ++L+H +V++ Y +E +++Y++LEY + + ++L R L E E +
Sbjct: 127 IDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL 186
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAA-LESKDKLLETSCGSPHY 191
RQI+ G+ Y H I+HRDLK N ++ +K+ DFG+AA LE + T CG+P+Y
Sbjct: 187 RQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNY 246
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDD 251
+PE+++ HG ESD+W+ G ++Y +L GR PF E N++ ++ ++ MP
Sbjct: 247 LSPEVLN-KQGHGCESDIWALGCVMYTMLLGRPPF--ETTNLKETYRCIREARYTMP--S 301
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKH 281
+ + A+ LIA +L+ +PE R +I++H
Sbjct: 302 SLLAPAKHLIASMLSKNPEDRPSLDDIIRH 331
>At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 554
Score = 138 bits (348), Expect = 4e-32
Identities = 90/274 (32%), Positives = 140/274 (50%), Gaps = 19/274 (6%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ LG LG G G + G A K I K + D D ++RE
Sbjct: 102 YTLGKELGRGQFGITYTCKENSTGNTYACKSILKRKLTRK-------QDID----DVKRE 150
Query: 77 IIIMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
I IM+ L+ N++ + +E + +++V+E ELF+ ++ +G E A R +
Sbjct: 151 IQIMQYLSGQENIVEIKGAYEDRQSIHLVMELCGGSELFDRIIAQGHYSEKAAAGVIRSV 210
Query: 136 IIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
+ + CH +G++HRDLKPEN LL D +K DFG++ + K+ GS +Y
Sbjct: 211 LNVVQICHFMGVIHRDLKPENFLLASTDENAMLKATDFGLSVFIEEGKVYRDIVGSAYYV 270
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGDD 251
APE++ +G E D+WS G+ILY LL G PF E + I N ++K + F+
Sbjct: 271 APEVLR--RSYGKEIDIWSAGIILYILLCGVPPFWSETEKGIFNEIIKGEI-DFDSQPWP 327
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
IS A+DL+ ++LT DP+QRI + L+HP +R
Sbjct: 328 SISESAKDLVRKLLTKDPKQRISAAQALEHPWIR 361
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 138 bits (348), Expect = 4e-32
Identities = 94/303 (31%), Positives = 162/303 (53%), Gaps = 44/303 (14%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYG 72
+I +++ ++ G+ G V++A T G A+K++ K+ MI N + +
Sbjct: 824 SIDDFEVMKSISRGAFGHVILARKNTTGDLFAIKVLRKA-------DMIRKNAVESIL-- 874
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
ER+I+I +P V+R + + S++LY+V+EY+ G+ +++L + G L E A +
Sbjct: 875 AERDILINA--RNPFVVRFFYSFTCSENLYLVMEYLNGGDFYSMLRKIGCLDEANARVYI 932
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMA------------------- 173
++++ + Y H+ G+VHRDLKP+NLL+ H +VKL DFG++
Sbjct: 933 AEVVLALEYLHSEGVVHRDLKPDNLLIAHDGHVKLTDFGLSKVGLINNTDDLSGPVSSAT 992
Query: 174 --ALESKDKL-----LETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF 226
+E K KL ++ G+P Y APEI+ G HG +D WS G+ILY L G PF
Sbjct: 993 SLLVEEKPKLPTLDHKRSAVGTPDYLAPEILLGTG-HGATADWWSVGIILYEFLVGIPPF 1051
Query: 227 DEEDGNIRNLLLKVQSGKFEMPG-DDEISSEAQDLIARILTVDPEQRIKTR---EILKHP 282
+ + + + + + + + P +++S EA+DLI R+LT DP QR+ R E+ +H
Sbjct: 1052 NAD--HPQQIFDNILNRNIQWPPVPEDMSHEARDLIDRLLTEDPHQRLGARGAAEVKQHS 1109
Query: 283 LLR 285
+
Sbjct: 1110 FFK 1112
>7304283 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7175
Score = 138 bits (348), Expect = 4e-32
Identities = 79/217 (36%), Positives = 127/217 (58%), Gaps = 8/217 (3%)
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERG-PLPENEAVRF 131
I REI IM L+H ++ L+D +E ++ ++LE++ GELF + G + E E + +
Sbjct: 6180 IRREIDIMNQLHHQKLINLHDAFEDDDEMILILEFLSGGELFERITAEGYVMTEAEVINY 6239
Query: 132 FRQIIIGISYCHALGIVHRDLKPENLLLDHK--FNVKLADFGMAALESKDKLLETSCGSP 189
RQI GI + H I+H D+KPEN++ + NVKL DFG+A +++++ + G+
Sbjct: 6240 MRQICEGIRHMHEQNIIHLDIKPENIMCQTRSSTNVKLIDFGLATRLDPNEVVKITTGTA 6299
Query: 190 HYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF--DEEDGNIRNLLLKVQSGKFEM 247
+AAPEIV+ P GF +D+W+ GV+ Y LL+G PF D + ++N +K F++
Sbjct: 6300 EFAAPEIVNREPV-GFYTDMWATGVLSYVLLSGLSPFAGDNDVQTLKN--VKACDWDFDV 6356
Query: 248 PGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLL 284
IS EA+D I ++L + E+R+ E L HP L
Sbjct: 6357 ESFKYISEEAKDFIRKLLVRNKEKRMTAHECLLHPWL 6393
>At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 595
Score = 138 bits (347), Expect = 6e-32
Identities = 94/278 (33%), Positives = 146/278 (51%), Gaps = 23/278 (8%)
Query: 17 WKLGSTLGVGSTGKVVMAYN---ETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
++LG +G G G + K AVKIISK A+ +T I D +
Sbjct: 143 YELGKEVGRGHFGHTCSGRGKKGDIKDHPIAVKIISK----AKMTTAIAIED-------V 191
Query: 74 EREIIIMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERG-PLPENEAVRF 131
RE+ ++K L+ H +++ YD E + ++Y+V+E + GEL + ++ RG PE++A
Sbjct: 192 RREVKLLKSLSGHKYLIKYYDACEDANNVYIVMELCDGGELLDRILARGGKYPEDDAKAI 251
Query: 132 FRQIIIGISYCHALGIVHRDLKPENLLLD---HKFNVKLADFGMAALESKDKLLETSCGS 188
QI+ +S+CH G+VHRDLKPEN L ++KL DFG++ D+ L GS
Sbjct: 252 VVQILTVVSFCHLQGVVHRDLKPENFLFTSSREDSDLKLIDFGLSDFIRPDERLNDIVGS 311
Query: 189 PHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEM 247
+Y APE++ + E+D+WS GVI Y LL G PF + I +L+ + ++
Sbjct: 312 AYYVAPEVLH--RSYSLEADIWSIGVITYILLCGSRPFWARTESGIFRTVLRTEPNYDDV 369
Query: 248 PGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
P SSE +D + R+L D +R+ + L HP LR
Sbjct: 370 PW-PSCSSEGKDFVKRLLNKDYRKRMSAVQALTHPWLR 406
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 138 bits (347), Expect = 6e-32
Identities = 80/270 (29%), Positives = 134/270 (49%), Gaps = 16/270 (5%)
Query: 13 TIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYG 72
T + +G LG G G V +A + A+K++ K+ + +
Sbjct: 15 TTSDFDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQLQQSQ-----------VEHQ 63
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
+ RE+ I L HPN+LRLY + K +Y++LEY +GEL+ L + E A +
Sbjct: 64 LRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERRAATYV 123
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
+ + YCH ++HRD+KPENLL+ + +K+ADFG + + T CG+ Y
Sbjct: 124 ASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFNRR--RTMCGTLDYL 181
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDE 252
PE+V + H D+WS G++ Y L G PF+ + + ++ + P
Sbjct: 182 PPEMVESVE-HDASVDIWSLGILCYEFLYGVPPFEAREHS--ETYKRIVQVDLKFPPKPI 238
Query: 253 ISSEAQDLIARILTVDPEQRIKTREILKHP 282
+SS A+DLI+++L + QR+ ++L+HP
Sbjct: 239 VSSSAKDLISQMLVKESTQRLALHKLLEHP 268
>At1g53570 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 138 bits (347), Expect = 6e-32
Identities = 86/284 (30%), Positives = 145/284 (50%), Gaps = 11/284 (3%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
WK G LG G+ G+V + +N KG+ A+K + K I + Q S + L + +E
Sbjct: 214 WKKGKFLGSGTFGQVYLGFNSEKGKMCAIKEV-KVISDDQTSK-------ECLKQ-LNQE 264
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
I ++ L HPN+++ Y + + L + LEYV G + LL + G E + RQI+
Sbjct: 265 INLLNQLCHPNIVQYYGSELSEETLSVYLEYVSGGSIHKLLKDYGSFTEPVIQNYTRQIL 324
Query: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEI 196
G++Y H VHRD+K N+L+D +KLADFGMA + + + GSP++ APE+
Sbjct: 325 AGLAYLHGRNTVHRDIKGANILVDPNGEIKLADFGMAKHVTAFSTMLSFKGSPYWMAPEV 384
Query: 197 VSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISSE 256
V + D+WS G + + T + P+ + +G + K+ + K D +S++
Sbjct: 385 VMSQNGYTHAVDIWSLGCTILEMATSKPPWSQFEGVA--AIFKIGNSKDTPEIPDHLSND 442
Query: 257 AQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLP 300
A++ I L +P R ++L+HP LR + + ++ P
Sbjct: 443 AKNFIRLCLQRNPTVRPTASQLLEHPFLRNTTRVASTSLPKDFP 486
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 137 bits (346), Expect = 7e-32
Identities = 88/291 (30%), Positives = 151/291 (51%), Gaps = 18/291 (6%)
Query: 75 REIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQ 134
+EI I + LNHPN+++ ++ +E S+++Y+VLE +K + L R + E E + Q
Sbjct: 72 QEITIHRSLNHPNIVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSITEFECRYYIYQ 131
Query: 135 IIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAA-LESKDKLLETSCGSPHYAA 193
II G+ Y H I+HRDLK NL L+ +VK+ DFG+A +E + + +T CG+P+Y A
Sbjct: 132 IIQGVKYLHDNRIIHRDLKLGNLFLNDLLHVKIGDFGLATRIEYEGERKKTLCGTPNYIA 191
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
PEI++ H FE D+WS G ++Y LL G+ PF E +++ K++ ++ +P +
Sbjct: 192 PEILT-KKGHSFEVDIWSIGCVMYTLLVGQPPF--ETKTLKDTYSKIKKCEYRVP--SYL 246
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLR--KYPSIKDSKSIRNLPREDTYLNPLSL 311
A D++ +L +PE R ++L L+ K P S + PR
Sbjct: 247 RKPAADMVIAMLQPNPESRPAIGQLLNFEFLKGSKVPMFLPSSCLTMAPR---------- 296
Query: 312 EGGNQCVDETILQNLVVLWHGRNKEDIITKLMEPGANLEKTFYALLHRFKH 362
G N +++++ + ++ +G +D + ANL A +H
Sbjct: 297 IGSNDTIEDSMHRKPLMEMNGIRPDDTRLESTFLKANLHDAITASAQVCRH 347
>YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 447
Score = 137 bits (345), Expect = 9e-32
Identities = 96/297 (32%), Positives = 146/297 (48%), Gaps = 25/297 (8%)
Query: 20 GSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIII 79
G TLG GS G V A + + A+KI+ K GN+ + + E+ I
Sbjct: 50 GRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQ--------GNNVQLQM--LYEELSI 99
Query: 80 MKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGI 139
++ L+HPN++ D +E+ Y+V + GELF+ ++ RG E +AV QI+ +
Sbjct: 100 LQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAV 159
Query: 140 SYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMA-ALESKDKLLETSCGSPHYAAPE 195
Y H+ +VHRDLKPEN+L K + +ADFG+A L+ ++ L+ + GS Y APE
Sbjct: 160 EYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPE 219
Query: 196 IVSGLPYHGFESDVWSCGVILYALLTGRLPFDEE--DGNIRNLLLKVQSGKFEMPGDDEI 253
+++ HG D+WS GVI Y LL G PF E +G + F MP D I
Sbjct: 220 VLT-QDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNI 278
Query: 254 SSEAQDLIARILTVDPEQRIKTREILKHPLLRK--------YPSIKDSKSIRNLPRE 302
S + + I + L ++P R E+L P + P +K S+R R+
Sbjct: 279 SIDVKRFILKALRLNPADRPTATELLDDPWITSKRVETSNILPDVKKGFSLRKKLRD 335
>Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1050
Score = 137 bits (345), Expect = 9e-32
Identities = 94/298 (31%), Positives = 150/298 (49%), Gaps = 29/298 (9%)
Query: 12 DTIGPWKLG--STLGVGSTGKVVMA-YNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDV 68
+T+G ++ +G G+ V + E + AVK I+K A+ T++G
Sbjct: 9 ETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNL-AKSQTLLG------ 61
Query: 69 LPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEA 128
+EI I+K L H N++ LYD E + +Y+V+EY G+L + L L E+
Sbjct: 62 ------KEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTI 115
Query: 129 VRFFRQIIIGISYCHALGIVHRDLKPENLLLD---------HKFNVKLADFGMAALESKD 179
F +QI + H+ GI+HRDLKP+N+LL + VK+ADFG A +
Sbjct: 116 RLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSN 175
Query: 180 KLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLK 239
+ T CGSP Y APE++ Y G ++D+WS G I+Y LTG+ PF + + ++L L
Sbjct: 176 MMAATLCGSPMYMAPEVIMSQHYDG-KADLWSIGTIVYQCLTGKAPF--QASSPQDLRLF 232
Query: 240 VQSGKFEMPG-DDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSI 296
+ K +P E S+ + L+ +L + + R+ E HP L PS++ S +
Sbjct: 233 YEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASPSVRKSPPV 290
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 137 bits (345), Expect = 9e-32
Identities = 91/287 (31%), Positives = 152/287 (52%), Gaps = 25/287 (8%)
Query: 2 NGNGITTLKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMI 61
N +G+ K T+ ++ LG G+ GKV++ + + A+KI+ K + +
Sbjct: 173 NSSGV---KKVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQK----- 224
Query: 62 GGNDPDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERG 121
D + + + E ++K NHP ++ L ++T+ L V++YV GELF L
Sbjct: 225 -----DEVAHTLT-ESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHER 278
Query: 122 PLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALE-SKDK 180
E+ + +II + Y H+ GI++RDLK ENLLLD ++K+ADFG+ + + +
Sbjct: 279 IFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGR 338
Query: 181 LLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKV 240
+T CG+P Y APE++ Y G D W GV++Y ++ GRLPF D ++ L+ V
Sbjct: 339 TTKTFCGTPEYLAPEVLDDNDY-GQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILV 397
Query: 241 QSGKFEMPGDDEISSEAQDLIARILTVDPEQRI-----KTREILKHP 282
+ KF I+ EA++L+A +L DP++R+ +EI HP
Sbjct: 398 EEVKFPR----NITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHP 440
>CE02604 [T] KOG0695 Serine/threonine protein kinase
Length = 597
Score = 137 bits (344), Expect = 1e-31
Identities = 89/280 (31%), Positives = 150/280 (52%), Gaps = 21/280 (7%)
Query: 1 MNGNGITTLKGDTIGPWKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTM 60
MNGNG ++ ++ ++L + +G GS KVV A + + Q A+KII K +FN
Sbjct: 238 MNGNG-SSKWAVSLNDFRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFN------ 290
Query: 61 IGGNDPDVLPYGIEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVER 120
D D+ E+ + N+P ++ L+ ++T L+ V+E+V G+L + ++
Sbjct: 291 ---EDEDIDWVQTEKSVF-EAASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQ 346
Query: 121 GPLPENEAVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKD- 179
LPE A + +II+ + + H+ GI++RDLK +N+L+D + ++KL D+GM KD
Sbjct: 347 RKLPEEHARFYSGEIILALHFLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDG 406
Query: 180 KLLETSCGSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFD------EEDGNI 233
L T CG+P+Y APEI+ G Y GF D W+ GV+++ ++ GR PFD E+
Sbjct: 407 DLTSTFCGTPNYIAPEILRGDEY-GFSVDWWALGVLMFEMMAGRSPFDIVGMQNSEENTE 465
Query: 234 RNLLLKVQSGKFEMPGDDEISSEAQDLIARILTVDPEQRI 273
L + + +P +S A ++ L DP +R+
Sbjct: 466 DYLFQIILERQIRIP--RSLSVRASGILKGFLNKDPTERL 503
>7300778 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 450
Score = 137 bits (344), Expect = 1e-31
Identities = 101/314 (32%), Positives = 152/314 (48%), Gaps = 25/314 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
++L +G G V + QQ AVKI+ + F A P + ++RE
Sbjct: 12 YELCEVIGKGPFSIVRRCIHRESNQQFAVKIVDVAKFTAS---------PGLSTADLKRE 62
Query: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPL----PENEAVRFF 132
I +L HP+++ L + + + LYMV E++E +L +V R E A +
Sbjct: 63 ATICHMLKHPHIVELLETYSSEGMLYMVFEFMEGSDLCFEVVRRAVAGFVYSEAVACHYM 122
Query: 133 RQIIIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAA-LESKDKLLETS--C 186
RQI+ + YCH I+HRD++P LL D+ VKL FG A L + +ET
Sbjct: 123 RQILEALRYCHENDILHRDVRPACALLATVDNSAPVKLGGFGSAIQLPGTRETIETHGRV 182
Query: 187 GSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGK-- 244
G PHY APE+V+ Y G DVW GV+L+ LL+GRLPF G+ L V G+
Sbjct: 183 GCPHYMAPEVVTRRLY-GKGCDVWGAGVMLHVLLSGRLPFL---GSGVRLQQSVARGRLS 238
Query: 245 FEMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDSKSIRNLPREDT 304
FE P IS+ A+DL+ ++L +P R+ E+L HP +R ++ + +
Sbjct: 239 FEAPEWKSISANAKDLVMKMLAANPHHRLSITEVLDHPWIRDRDKLQRTHLADTVEELKR 298
Query: 305 YLNPLSLEGGNQCV 318
Y L+G Q +
Sbjct: 299 YNARRKLKGAVQAI 312
>CE17343 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 136 bits (343), Expect = 2e-31
Identities = 93/274 (33%), Positives = 133/274 (47%), Gaps = 13/274 (4%)
Query: 17 WKLG--STLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIE 74
WKL LG GS +V A K + A KII+ + + D + +
Sbjct: 67 WKLKFEKVLGSGSYSRVARATFGEKKLEVAAKIINITPTREK---------EDYIKKFLP 117
Query: 75 REIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQ 134
RE I+KLL H N+ RLY++ + V EY G+L + + + E +A FRQ
Sbjct: 118 REKEIVKLLKHDNICRLYEMISFQDHIIFVNEYCAGGDLLRKMKDIVAMKEEDAKFTFRQ 177
Query: 135 IIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCGSPHYAAP 194
+I +++ + IVHRDLK EN+ +D NVKL DFG + + + T CGS Y AP
Sbjct: 178 LIAALTHLQSYNIVHRDLKCENIFMDKHGNVKLGDFGFSRILKPGEKSGTFCGSRAYVAP 237
Query: 195 EIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEIS 254
EI G Y G DVWS GVILY +L G +PFD+ D R ++ + + K + P S
Sbjct: 238 EIFRGREYSGNAVDVWSTGVILYIMLAGSMPFDDRDP--RKMIERQLAHKIKFPKSCTSS 295
Query: 255 SEAQDLIARILTVDPEQRIKTREILKHPLLRKYP 288
++ L+ IL R + I + LR P
Sbjct: 296 VFSKALVLEILQPHAPNRPTYKAICESEWLRTQP 329
>At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 560
Score = 136 bits (343), Expect = 2e-31
Identities = 95/302 (31%), Positives = 153/302 (50%), Gaps = 24/302 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ LG LG G G + ++ A K SI + T + D + RE
Sbjct: 63 YTLGRELGRGEFGVTYLCTDKETDDVFACK----SILKKKLRTAVDIED-------VRRE 111
Query: 77 IIIMKLL-NHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
+ IM+ + HPNV+ L + +E +++V+E E GELF+ +V RG E A + I
Sbjct: 112 VEIMRHMPEHPNVVTLKETYEDEHAVHLVMELCEGGELFDRIVARGHYTERAAAAVTKTI 171
Query: 136 IIGISYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYA 192
+ + CH G++HRDLKPEN L +K +K DFG++ + GSP+Y
Sbjct: 172 MEVVQVCHKHGVMHRDLKPENFLFGNKKETAPLKAIDFGLSVFFKPGERFNEIVGSPYYM 231
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPF--DEEDGNIRNLLLKVQSGKFEMPGD 250
APE++ +G E D+WS GVILY LL G PF + E G + ++ V F
Sbjct: 232 APEVLK--RNYGPEVDIWSAGVILYILLCGVPPFWAETEQGVAQAIIRSVLD--FRRDPW 287
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLL---RKYPSIKDSKSIRNLPREDTYLN 307
++S A+DLI ++L D ++R+ +++L HP L + P++ +++R ++ T +N
Sbjct: 288 PKVSENAKDLIRKMLDPDQKRRLTAQQVLDHPWLQNAKTAPNVSLGETVRARLKQFTVMN 347
Query: 308 PL 309
L
Sbjct: 348 KL 349
>At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 582
Score = 136 bits (343), Expect = 2e-31
Identities = 95/299 (31%), Positives = 151/299 (49%), Gaps = 22/299 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ LG LG G G + ++ A K ISK T I D + RE
Sbjct: 66 YDLGKELGRGEFGVTHECIEISTRERFACKRISKEKLR----TEIDVED-------VRRE 114
Query: 77 IIIMKLL-NHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
+ IM+ L HPN++ + +E +Y+V+E E GELF+ +V RG E A + I
Sbjct: 115 VEIMRCLPKHPNIVSFKEAFEDKDAVYLVMEICEGGELFDRIVSRGHYTERAAASVAKTI 174
Query: 136 IIGISYCHALGIVHRDLKPENLLLDH---KFNVKLADFGMAALESKDKLLETSCGSPHYA 192
+ + CH G++HRDLKPEN L + +K DFG++ + GSP+Y
Sbjct: 175 LEVVKVCHEHGVIHRDLKPENFLFSNGTETAQLKAIDFGLSIFFKPAQRFNEIVGSPYYM 234
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKFEMPGDD 251
APE++ +G E DVWS GVILY LL G PF E + I + +++ + FE
Sbjct: 235 APEVLR--RNYGPEIDVWSAGVILYILLCGVPPFWAETEEGIAHAIVR-GNIDFERDPWP 291
Query: 252 EISSEAQDLIARILTVDPEQRIKTREILKHPLLR---KYPSIKDSKSIRNLPREDTYLN 307
++S EA++L+ +L +P R+ +E+L+HP +R + P++ ++R ++ +N
Sbjct: 292 KVSHEAKELVKNMLDANPYSRLTVQEVLEHPWIRNAERAPNVNLGDNVRTKIQQFLLMN 350
>At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 136 bits (342), Expect = 2e-31
Identities = 95/280 (33%), Positives = 149/280 (52%), Gaps = 23/280 (8%)
Query: 15 GPWKLGSTLGVGSTGKVVMAY---NETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPY 71
G ++LG +G G G A + K Q AVKIISK A+ ++ + D
Sbjct: 141 GKYELGKEVGRGHFGHTCWAKAKKGKMKNQTVAVKIISK----AKMTSTLSIED------ 190
Query: 72 GIEREIIIMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGP-LPENEAV 129
+ RE+ ++K L+ H ++++ YDV+E + ++++V+E E GEL + ++ RG PE +A
Sbjct: 191 -VRREVKLLKALSGHRHMVKFYDVYEDADNVFVVMELCEGGELLDRILARGGRYPEVDAK 249
Query: 130 RFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSC 186
R QI+ ++ H G+VHRDLKPEN L + +K+ DFG++ D+ L
Sbjct: 250 RILVQILSATAFFHLQGVVHRDLKPENFLFTSRNEDAILKVIDFGLSDFIRYDQRLNDVV 309
Query: 187 GSPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF-DEEDGNIRNLLLKVQSGKF 245
GS +Y APE++ + E+D+WS GVI Y LL G PF + I +L+
Sbjct: 310 GSAYYVAPEVLH--RSYSTEADMWSIGVISYILLCGSRPFYGRTESAIFRCVLRANPNFE 367
Query: 246 EMPGDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
+MP IS A+D + R+L D +R+ + L HP LR
Sbjct: 368 DMPW-PSISPTAKDFVKRLLNKDHRKRMTAAQALAHPWLR 406
>SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 445
Score = 135 bits (341), Expect = 3e-31
Identities = 88/281 (31%), Positives = 138/281 (48%), Gaps = 34/281 (12%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG+G ++ MA + G Q A KII K + + + + E+ I++
Sbjct: 166 LGIGGFSRIYMAMDNNTGGQYACKIIDKKKISTKR-------------FFEDHEMTILRK 212
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L+HPN++++ + + ++ E V G+LF+ L + G +PE + QI+ G+ Y
Sbjct: 213 LDHPNIIKVNMEYNSETQFFIFEEMVTGGDLFSYLTKLGTVPEVTTLFIMFQILQGLKYL 272
Query: 143 HALGIVHRDLKPENLLL----DHKFNVKLADFGMAALESKDKLLETSCGSPHYAAPEI-- 196
H I+HRDLK EN+L+ D F + L DFG+A K K L T G+P Y APEI
Sbjct: 273 HEQNIIHRDLKLENILIASSSDTIFRIILTDFGVARCMQKGKRLSTFVGTPEYTAPEIQR 332
Query: 197 --------VSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMP 248
+G E D+WS GVI++ LL+G P DG +K + F P
Sbjct: 333 LKGRSQVEKENSSGYGKEVDLWSLGVIMFLLLSGNSP-SFADG------VKEKQVDFRDP 385
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPS 289
+S +A+DLI+ +L +P R ++ L HP ++ S
Sbjct: 386 VWKSVSRQAKDLISNLLKTNPPDRFTVKQCLSHPWFARHSS 426
>CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 469
Score = 135 bits (341), Expect = 3e-31
Identities = 90/266 (33%), Positives = 142/266 (52%), Gaps = 19/266 (7%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG G GKV++ Y ++ A+K ++ + D I+ E+ +MK
Sbjct: 175 LGKGGFGKVLLGYKKSDRSVVAIKQLNTQFSTRCSRAIAKTRD-------IQNEVEVMKK 227
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVE----RGPLPENEAVRFFRQIIIG 138
L+HPN++ +YD +K YMV+EYV GE F+ LV+ + L E+ F Q+I
Sbjct: 228 LSHPNIVAIYDCITVAKYSYMVIEYVGGGEFFSKLVDSKYNQMGLGESLGKYFAFQLIDA 287
Query: 139 ISYCHALGIVHRDLKPENLLLDHKFN---VKLADFGMAALESKDKLLETSCGSPHYAAPE 195
+ Y H++GI HRD+KPEN+L +K +KL DFGMA ++ ++T CG+P Y APE
Sbjct: 288 VLYLHSVGICHRDIKPENILCSNKAERCILKLTDFGMA--KNSVNRMKTHCGTPSYCAPE 345
Query: 196 IVS--GLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEI 253
IV+ G+ Y + D+WS G +L+ +G PF EE +++ + F I
Sbjct: 346 IVANQGVEYTP-KVDIWSLGCVLFITFSGYPPFSEEYTDLKMDEQVLTGRLFFHEQWHRI 404
Query: 254 SSEAQDLIARILTVDPEQRIKTREIL 279
+ E Q++I +LTV+P R E++
Sbjct: 405 TDETQNMIQWMLTVEPLIRPSAVELM 430
>At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 529
Score = 135 bits (341), Expect = 3e-31
Identities = 86/276 (31%), Positives = 142/276 (51%), Gaps = 21/276 (7%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
++ G LG G G + ++ QQ A K I ++ +D + + RE
Sbjct: 78 YEFGRELGRGQFGVTYLVTHKETKQQVACKSIPTR-------RLVHKDDIE----DVRRE 126
Query: 77 IIIMKLLN-HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQI 135
+ IM L+ H N++ L +E + +++E E GELF+ ++ +G E A RQ+
Sbjct: 127 VQIMHHLSGHRNIVDLKGAYEDRHSVNLIMELCEGGELFDRIISKGLYSERAAADLCRQM 186
Query: 136 IIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPHYA 192
++ + CH++G++HRDLKPEN L D +K DFG++ + GS +Y
Sbjct: 187 VMVVHSCHSMGVMHRDLKPENFLFLSKDENSPLKATDFGLSVFFKPGDKFKDLVGSAYYV 246
Query: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD-- 250
APE++ +G E+D+WS GVILY LL+G PF E N + + G+ + D
Sbjct: 247 APEVLK--RNYGPEADIWSAGVILYILLSGVPPFWGE--NETGIFDAILQGQLDFSADPW 302
Query: 251 DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
+S A+DL+ ++L DP+ R+ E+L HP +R+
Sbjct: 303 PALSDGAKDLVRKMLKYDPKDRLTAAEVLNHPWIRE 338
>At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 135 bits (341), Expect = 3e-31
Identities = 94/278 (33%), Positives = 139/278 (49%), Gaps = 23/278 (8%)
Query: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
+ +G LG G G +A ++ G + AVK I K A+ + I D ++RE
Sbjct: 108 YTIGKLLGHGQFGYTYVATDKKTGDRVAVKKIDK----AKMTIPIAVED-------VKRE 156
Query: 77 I-IIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVER--GPLPENEAVRFFR 133
+ I+ L H NV+R Y+ +E +Y+V+E E GEL + ++ R E +A R
Sbjct: 157 VKILQALTGHENVVRFYNAFEDKNSVYIVMELCEGGELLDRILARKDSRYSERDAAVVVR 216
Query: 134 QIIIGISYCHALGIVHRDLKPENLLL---DHKFNVKLADFGMAALESKDKLLETSCGSPH 190
Q++ + CH G+VHRD+KPEN L + +K DFG++ K GS +
Sbjct: 217 QMLKVAAECHLRGLVHRDMKPENFLFKSTEEDSPLKATDFGLSDFIKPGKKFHDIVGSAY 276
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF--DEEDGNIRNLLLKVQSGKFEMP 248
Y APE++ G ESDVWS GVI Y LL GR PF EDG + +L F
Sbjct: 277 YVAPEVLK--RRSGPESDVWSIGVISYILLCGRRPFWDKTEDGIFKEVL--KNKPDFRRK 332
Query: 249 GDDEISSEAQDLIARILTVDPEQRIKTREILKHPLLRK 286
IS+ A+D + ++L DP R+ + L HP +R+
Sbjct: 333 PWPTISNSAKDFVKKLLVKDPRARLTAAQALSHPWVRE 370
>At1g63700 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 883
Score = 135 bits (341), Expect = 3e-31
Identities = 85/279 (30%), Positives = 139/279 (49%), Gaps = 20/279 (7%)
Query: 13 TIGP---WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVL 69
T+ P WK G LG+GS G V + +N G+ A+K ++ + +DP
Sbjct: 393 TVSPGSRWKKGRLLGMGSFGHVYLGFNSESGEMCAMKEVT-----------LCSDDPKSR 441
Query: 70 PYG--IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENE 127
+ +EI ++ L H N+++ Y LY+ LEYV G ++ LL E G EN
Sbjct: 442 ESAQQLGQEISVLSRLRHQNIVQYYGSETVDDKLYIYLEYVSGGSIYKLLQEYGQFGENA 501
Query: 128 AVRFFRQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKLLETSCG 187
+ +QI+ G++Y HA VHRD+K N+L+D VK+ADFGMA + + G
Sbjct: 502 IRNYTQQILSGLAYLHAKNTVHRDIKGANILVDPHGRVKVADFGMAKHITAQSGPLSFKG 561
Query: 188 SPHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEM 247
SP++ APE++ D+WS G + + T + P+ + +G + K+ + K E+
Sbjct: 562 SPYWMAPEVIKNSNGSNLAVDIWSLGCTVLEMATTKPPWSQYEG--VPAMFKIGNSK-EL 618
Query: 248 PG-DDEISSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
P D +S E +D + + L +P R ++L H +R
Sbjct: 619 PDIPDHLSEEGKDFVRKCLQRNPANRPTAAQLLDHAFVR 657
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 135 bits (341), Expect = 3e-31
Identities = 89/273 (32%), Positives = 147/273 (53%), Gaps = 25/273 (9%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
+G GS G+V + GQ A+K I K QG T D D+ + + +EI I++
Sbjct: 12 VGEGSFGRVYKGRRKYTGQTVAMKFIMK-----QGKT-----DKDI--HSLRQEIEILRK 59
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
L H N++ + D +E +++ +V E+ + GELF +L + LPE + +Q++ + Y
Sbjct: 60 LKHENIIEMLDSFENAREFCVVTEFAQ-GELFEILEDDKCLPEEQVQAIAKQLVKALDYL 118
Query: 143 HALGIVHRDLKPENLLLDHKFNVKLADFGMA-ALESKDKLLETSCGSPHYAAPEIVSGLP 201
H+ I+HRD+KP+N+L+ VKL DFG A A+ + +L + G+P Y APE+V P
Sbjct: 119 HSNRIIHRDMKPQNILIGAGSVVKLCDFGFARAMSTNTVVLRSIKGTPLYMAPELVKEQP 178
Query: 202 YHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGDDEISSEAQDLI 261
Y D+WS GVILY L G+ PF ++ L+ + + P DE+S+ + +
Sbjct: 179 YDR-TVDLWSLGVILYELYVGQPPF--YTNSVYALIRHIVKDPVKYP--DEMSTYFESFL 233
Query: 262 ARILTVDPEQRIKTREILKHPLLRKYPSIKDSK 294
+L +P R L P LR++P +K+++
Sbjct: 234 KGLLNKEPHSR------LTWPALREHPFVKETQ 260
>CE21086 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 637
Score = 135 bits (340), Expect = 4e-31
Identities = 78/215 (36%), Positives = 124/215 (57%), Gaps = 19/215 (8%)
Query: 23 LGVGSTGKVVM-AYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMK 81
LG GS +VV+ A T + A+K IS I G D + I+RE I K
Sbjct: 24 LGEGSFAEVVLVAKVGTPNKMFAMKEIS-----------IVGKD-ECFMESIKRECSIQK 71
Query: 82 LLN---HPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIG 138
L+ H N++ L+++ ++ ++L Y + G+LF + + G L +EA R+F+Q+I G
Sbjct: 72 RLSKSRHLNMIHLFEIRTNPENYQLILSYADGGDLFEKINQHGGLGSDEAHRYFKQLIDG 131
Query: 139 ISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAAL---ESKDKLLETSCGSPHYAAPE 195
+ + H G+ HRD+KPENLLL +K+ADFG A + +++L CGSP Y APE
Sbjct: 132 LRFIHEEGVTHRDIKPENLLLTKSGILKIADFGFATMHRFNGAEQMLNAYCGSPPYIAPE 191
Query: 196 IVSGLPYHGFESDVWSCGVILYALLTGRLPFDEED 230
+++G+ Y G D+WS GV+L A++ G +P+++ D
Sbjct: 192 VLTGIDYRGPAVDIWSAGVVLIAMIAGAVPWEQAD 226
Score = 117 bits (292), Expect = 1e-25
Identities = 74/216 (34%), Positives = 114/216 (52%), Gaps = 16/216 (7%)
Query: 83 LNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISYC 142
+ H NV+++ + ET K +V+EY + G+LF+ L E+ +A +F+Q+I G+ +
Sbjct: 401 IGHENVIQMMKMIETPKFYSLVMEYADGGDLFDELKEQEKFSRKDAHSYFKQLIKGLKFI 460
Query: 143 HALGIVHRDLKPENLLL------DHKFNVKLADFGMAALESKDK---LLETSCGSPHYAA 193
H GIVHRD+K ENLLL D +K+ DFG+A KD +L CGS YAA
Sbjct: 461 HEQGIVHRDIKLENLLLVYSESEDDPGTLKITDFGLATKYRKDGEEIMLSEDCGSKPYAA 520
Query: 194 PEIVSGLPYHGFESDVWSCGVILYALLTG----RLPFDEEDGNIRNLLLKVQSGKFEMPG 249
PE+ +G Y G D+WS GV+L +L G ++ E+D N + + K +
Sbjct: 521 PEVCTGNDYRGPPVDIWSAGVVLMTMLVGEHSWKVANKEKDAAYSN-WINAKDEKANL-- 577
Query: 250 DDEISSEAQDLIARILTVDPEQRIKTREILKHPLLR 285
+ IS L+ ++L +PE+R +I P R
Sbjct: 578 WNVISGPTTALLRKLLHANPEKRATMAKIEADPWFR 613
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 135 bits (339), Expect = 5e-31
Identities = 89/266 (33%), Positives = 140/266 (52%), Gaps = 32/266 (12%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LG GS GQ+ AVKI+S+ L +RE+ ++L
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSRR-----------------LEANTQREVAALRL 459
Query: 83 L-NHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQIIIGISY 141
+HPNV+ L++V Y+VLE + GEL + ++ E+EA + R ++ +S+
Sbjct: 460 CQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSF 519
Query: 142 CH-ALGIVHRDLKPENLLLDHK---FNVKLADFGMAAL--ESKDKLLETSCGSPHYAAPE 195
H G+VHRDLKPEN+L VK+ DFG A L +S ++T C + YAAPE
Sbjct: 520 MHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPE 579
Query: 196 IVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDG-----NIRNLLLKVQSGKFEMPGD 250
+++ Y D+WS GVILY +L+G++PF G ++ K++ G+F + G+
Sbjct: 580 LLAQQGYDE-SCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGE 638
Query: 251 --DEISSEAQDLIARILTVDPEQRIK 274
+S EA++L+ +LTVDP +R+K
Sbjct: 639 AWQGVSEEAKELVRGLLTVDPAKRLK 664
Score = 127 bits (319), Expect = 1e-28
Identities = 94/319 (29%), Positives = 154/319 (47%), Gaps = 36/319 (11%)
Query: 17 WKLGSTLGVGSTGKVVM---AYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGI 73
++L LG G+ GKV + A G+ A+K++ K+ + T
Sbjct: 33 FELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRT-------- 84
Query: 74 EREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFR 133
ER ++ + + P ++ L+ ++T L+++L+YV GE+F L +R E E +
Sbjct: 85 ERSVLEL-VRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGG 143
Query: 134 QIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMA---ALESKDKLLETSCGSPH 190
+I++ + + H LGI++RDLK EN+LLD + ++ L DFG++ E K++ + CG+
Sbjct: 144 EIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTF-SFCGTIE 202
Query: 191 YAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGKFEMPGD 250
Y APEI+ HG D WS G++L+ LLTG PF E + + K P
Sbjct: 203 YMAPEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFP 262
Query: 251 DEISSEAQDLIARILTVDPEQRI-----KTREILKHPLL----------RKYPS-----I 290
I AQDL+ R+L DP++R+ +E+ HP RK P+ I
Sbjct: 263 PRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQI 322
Query: 291 KDSKSIRNLPREDTYLNPL 309
+ + N E T L P+
Sbjct: 323 RSELDVGNFAEEFTRLEPV 341
>CE06635 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7160
Score = 135 bits (339), Expect = 5e-31
Identities = 78/221 (35%), Positives = 126/221 (56%), Gaps = 16/221 (7%)
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLV-ERGPLPENEAVRF 131
+ +EI M +L HP ++ L+D +E ++ M+ E++ GELF + E + E+EAV +
Sbjct: 6305 VRKEIQTMSVLRHPTLVNLHDAFEDDNEMVMIYEFMSGGELFEKVADEHNKMSEDEAVEY 6364
Query: 132 FRQIIIGISYCHALGIVHRDLKPENLLLDHKFN--VKLADFGMAALESKDKLLETSCGSP 189
RQ+ G+ + H VH DLKPEN++ K + +KL DFG+ A + ++ + G+
Sbjct: 6365 MRQVCKGLCHMHENNYVHLDLKPENIMFTTKRSNELKLIDFGLTAHLDPKQSVKVTTGTA 6424
Query: 190 HYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF--DEEDGNIRNLLLKVQSGKFEM 247
+AAPE+ G P G+ +D+WS GV+ Y LL+G PF + +D +RN V+S + M
Sbjct: 6425 EFAAPEVAEGKPV-GYYTDMWSVGVLSYILLSGLSPFGGENDDETLRN----VKSCDWNM 6479
Query: 248 PGDDE----ISSEAQDLIARILTVDPEQRIKTREILKHPLL 284
DD IS + +D I ++L DP R+ + L+HP L
Sbjct: 6480 --DDSAFSGISEDGKDFIRKLLLADPNTRMTIHQALEHPWL 6518
>CE06634 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 6831
Score = 135 bits (339), Expect = 5e-31
Identities = 78/221 (35%), Positives = 126/221 (56%), Gaps = 16/221 (7%)
Query: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLV-ERGPLPENEAVRF 131
+ +EI M +L HP ++ L+D +E ++ M+ E++ GELF + E + E+EAV +
Sbjct: 5976 VRKEIQTMSVLRHPTLVNLHDAFEDDNEMVMIYEFMSGGELFEKVADEHNKMSEDEAVEY 6035
Query: 132 FRQIIIGISYCHALGIVHRDLKPENLLLDHKFN--VKLADFGMAALESKDKLLETSCGSP 189
RQ+ G+ + H VH DLKPEN++ K + +KL DFG+ A + ++ + G+
Sbjct: 6036 MRQVCKGLCHMHENNYVHLDLKPENIMFTTKRSNELKLIDFGLTAHLDPKQSVKVTTGTA 6095
Query: 190 HYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPF--DEEDGNIRNLLLKVQSGKFEM 247
+AAPE+ G P G+ +D+WS GV+ Y LL+G PF + +D +RN V+S + M
Sbjct: 6096 EFAAPEVAEGKPV-GYYTDMWSVGVLSYILLSGLSPFGGENDDETLRN----VKSCDWNM 6150
Query: 248 PGDDE----ISSEAQDLIARILTVDPEQRIKTREILKHPLL 284
DD IS + +D I ++L DP R+ + L+HP L
Sbjct: 6151 --DDSAFSGISEDGKDFIRKLLLADPNTRMTIHQALEHPWL 6189
>CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 425
Score = 134 bits (338), Expect = 6e-31
Identities = 94/286 (32%), Positives = 149/286 (51%), Gaps = 34/286 (11%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LGVG GKVV + G + A+K++ D E E+ +M
Sbjct: 78 LGVGINGKVVECEHRQSGDKFALKVLR-----------------DTQKARREVELHVMAS 120
Query: 83 LNHPNVLRLYDVWETSKD----LYMVLEYVEKGELFNLLVERGP--LPENEAVRFFRQII 136
H +V+ ++DV++ S + L +V+E ++ GELFN + ERG E EA +I
Sbjct: 121 -GHGHVVSVHDVYKNSYNGVDCLLVVMENMKGGELFNRIQERGQKAFTEREAAGIVNEIC 179
Query: 137 IGISYCHALGIVHRDLKPENLL---LDHKFNVKLADFGMAAL--ESKDKLLETSCGSPHY 191
+++ H + I HRDLKPENLL +KL DFG A ES+ + L+T+C +P+Y
Sbjct: 180 SAVAHLHRMSIAHRDLKPENLLYVTTASNAALKLTDFGFAKKTDESEPQGLKTACFTPYY 239
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRN--LLLKVQSGKFEMPG 249
APE++ G + D+WS GVI+Y LL G PF + G + + K++SG++ P
Sbjct: 240 CAPEVL-GTEKYDKSCDLWSIGVIMYILLCGYPPFYSQHGQPMSPGMKAKIKSGQYTFPS 298
Query: 250 D--DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDS 293
D +S A+DLI ++L +P +RI + ++H + Y + D+
Sbjct: 299 PEWDCVSEAAKDLIRKLLRTEPTERITIEQTMEHKWISHYRRVPDT 344
>CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 443
Score = 134 bits (338), Expect = 6e-31
Identities = 94/286 (32%), Positives = 149/286 (51%), Gaps = 34/286 (11%)
Query: 23 LGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIEREIIIMKL 82
LGVG GKVV + G + A+K++ D E E+ +M
Sbjct: 96 LGVGINGKVVECEHRQSGDKFALKVLR-----------------DTQKARREVELHVMAS 138
Query: 83 LNHPNVLRLYDVWETSKD----LYMVLEYVEKGELFNLLVERGP--LPENEAVRFFRQII 136
H +V+ ++DV++ S + L +V+E ++ GELFN + ERG E EA +I
Sbjct: 139 -GHGHVVSVHDVYKNSYNGVDCLLVVMENMKGGELFNRIQERGQKAFTEREAAGIVNEIC 197
Query: 137 IGISYCHALGIVHRDLKPENLL---LDHKFNVKLADFGMAAL--ESKDKLLETSCGSPHY 191
+++ H + I HRDLKPENLL +KL DFG A ES+ + L+T+C +P+Y
Sbjct: 198 SAVAHLHRMSIAHRDLKPENLLYVTTASNAALKLTDFGFAKKTDESEPQGLKTACFTPYY 257
Query: 192 AAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRN--LLLKVQSGKFEMPG 249
APE++ G + D+WS GVI+Y LL G PF + G + + K++SG++ P
Sbjct: 258 CAPEVL-GTEKYDKSCDLWSIGVIMYILLCGYPPFYSQHGQPMSPGMKAKIKSGQYTFPS 316
Query: 250 D--DEISSEAQDLIARILTVDPEQRIKTREILKHPLLRKYPSIKDS 293
D +S A+DLI ++L +P +RI + ++H + Y + D+
Sbjct: 317 PEWDCVSEAAKDLIRKLLRTEPTERITIEQTMEHKWISHYRRVPDT 362
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.312 0.131 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,275,036
Number of Sequences: 60738
Number of extensions: 2808324
Number of successful extensions: 14936
Number of sequences better than 1.0e-05: 1756
Number of HSP's better than 0.0 without gapping: 652
Number of HSP's successfully gapped in prelim test: 1104
Number of HSP's that attempted gapping in prelim test: 10085
Number of HSP's gapped (non-prelim): 2428
length of query: 1112
length of database: 30,389,216
effective HSP length: 117
effective length of query: 995
effective length of database: 23,282,870
effective search space: 23166455650
effective search space used: 23166455650
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)