ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0490 check: MH U KOG0058 Intracellular trafficking, secretion, and vesicular transport Peptide exporter, ABC superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0490 160778 162895 706
(706 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR188w [U] KOG0058 Peptide exporter ABC superfamily 844 0.0
YPL270w [U] KOG0058 Peptide exporter ABC superfamily 491 e-138
SPBC9B6.09c [U] KOG0058 Peptide exporter ABC superfamily 459 e-129
Hs9961244 [U] KOG0058 Peptide exporter ABC superfamily 409 e-113
CE16149 [U] KOG0058 Peptide exporter ABC superfamily 391 e-108
7290042 [U] KOG0058 Peptide exporter ABC superfamily 345 2e-94
At5g39040 [U] KOG0058 Peptide exporter ABC superfamily 335 1e-91
CE15650 [U] KOG0058 Peptide exporter ABC superfamily 311 2e-84
Hs9955966 [U] KOG0058 Peptide exporter ABC superfamily 296 6e-80
Hs6005804 [U] KOG0058 Peptide exporter ABC superfamily 290 5e-78
CE07240 [U] KOG0058 Peptide exporter ABC superfamily 286 6e-77
At1g27940 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 280 5e-75
7292782 [U] KOG0058 Peptide exporter ABC superfamily 279 9e-75
At1g02520 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 277 4e-74
At4g01820 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 275 2e-73
Hs4505769 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 274 4e-73
At3g62150 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 273 5e-73
Hs9961252 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 272 1e-72
Hs9961250 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 272 1e-72
Hs4505771 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 272 1e-72
At1g28010 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 271 2e-72
At1g02530 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 270 4e-72
At4g01830 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 270 7e-72
Hs9955968 [U] KOG0058 Peptide exporter ABC superfamily 269 1e-71
CE15714 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 269 1e-71
At3g28860 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 268 3e-71
CE28355 [U] KOG0058 Peptide exporter ABC superfamily 267 5e-71
At2g36910 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 267 5e-71
Hs21536378 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 266 8e-71
At1g10680 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 266 8e-71
HsM4502457 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 265 2e-70
CE23999 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 265 2e-70
At2g47000 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 265 2e-70
CE11932 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 263 5e-70
CE27353 [U] KOG0058 Peptide exporter ABC superfamily 263 9e-70
CE24404 [U] KOG0058 Peptide exporter ABC superfamily 263 9e-70
At3g28390 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 261 2e-69
At3g28360 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 261 3e-69
CE03260 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 260 4e-69
At3g28380 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 260 6e-69
At3g28345 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 259 1e-68
CE23998 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 257 4e-68
CE14926 [U] KOG0058 Peptide exporter ABC superfamily 256 8e-68
At5g46540 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 255 1e-67
7303208 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 253 5e-67
At4g25960 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 253 9e-67
CE06485 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 251 2e-66
CE03262 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 248 2e-65
CE29212 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 247 4e-65
CE03818 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 247 4e-65
CE03308 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 244 3e-64
Hs9665248 [U] KOG0058 Peptide exporter ABC superfamily 243 6e-64
CE03263 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 243 1e-63
At1g70610 [U] KOG0058 Peptide exporter ABC superfamily 242 1e-63
Hs9961246 [U] KOG0058 Peptide exporter ABC superfamily 242 2e-63
At4g18050 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 242 2e-63
CE05221 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 241 2e-63
SPCC663.03 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 239 1e-62
CE03261 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 238 2e-62
7303379 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 235 2e-61
7295351 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 231 2e-60
7295352 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 228 2e-59
At2g39480 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 227 4e-59
At3g55320 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 224 4e-58
Hs9961248 [U] KOG0058 Peptide exporter ABC superfamily 224 5e-58
CE24868 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 215 2e-55
At5g03910 [U] KOG0058 Peptide exporter ABC superfamily 204 3e-52
SPCC737.09c [P] KOG0056 Heavy metal exporter HMT1 ABC superfamily 204 5e-52
YKL209c [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 198 3e-50
CE04268 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 196 1e-49
Hs9955963 [P] KOG0056 Heavy metal exporter HMT1 ABC superfamily 186 8e-47
At5g58270 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC su... 186 8e-47
7300071 [P] KOG0056 Heavy metal exporter HMT1 ABC superfamily 186 8e-47
At4g28620 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC su... 179 1e-44
7292113 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC supe... 178 2e-44
At4g25450 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 178 3e-44
At4g28630 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC su... 172 1e-42
Hs4757706 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC su... 169 1e-41
Hs22058461 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC s... 169 1e-41
YMR301c [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC supe... 160 6e-39
SPAC15A10.01 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC... 156 9e-38
SPBC2G5.09c [Q] KOG0055 Multidrug/pheromone exporter ABC superfa... 152 2e-36
CE28847 [P] KOG0056 Heavy metal exporter HMT1 ABC superfamily 149 2e-35
SPBC359.05 [Q] KOG0054 Multidrug resistance-associated protein/m... 140 7e-33
YDR135c [Q] KOG0054 Multidrug resistance-associated protein/mito... 140 9e-33
SPAC3F10.11c [Q] KOG0054 Multidrug resistance-associated protein... 139 1e-32
CE25015 [Q] KOG0054 Multidrug resistance-associated protein/mito... 139 1e-32
Hs21541820 [Q] KOG0054 Multidrug resistance-associated protein/m... 138 3e-32
7297388 [Q] KOG0054 Multidrug resistance-associated protein/mito... 137 4e-32
Hs22057784 [U] KOG0058 Peptide exporter ABC superfamily 137 6e-32
CE04425 [Q] KOG0054 Multidrug resistance-associated protein/mito... 135 2e-31
7301757 [Q] KOG0054 Multidrug resistance-associated protein/mito... 135 2e-31
At1g30400 [Q] KOG0054 Multidrug resistance-associated protein/mi... 135 3e-31
CE29412 [Q] KOG0054 Multidrug resistance-associated protein/mito... 134 5e-31
7303902 [Q] KOG0054 Multidrug resistance-associated protein/mito... 134 5e-31
CE23037 [Q] KOG0054 Multidrug resistance-associated protein/mito... 132 1e-30
Hs4507317 [Q] KOG0054 Multidrug resistance-associated protein/mi... 132 2e-30
Hs10947122 [Q] KOG0054 Multidrug resistance-associated protein/m... 132 2e-30
7298738 [Q] KOG0054 Multidrug resistance-associated protein/mito... 131 4e-30
Hs5032135 [Q] KOG0054 Multidrug resistance-associated protein/mi... 129 1e-29
Hs10947124 [Q] KOG0054 Multidrug resistance-associated protein/m... 129 1e-29
At2g34660 [Q] KOG0054 Multidrug resistance-associated protein/mi... 129 1e-29
At2g07680 [Q] KOG0054 Multidrug resistance-associated protein/mi... 129 1e-29
At3g21250 [Q] KOG0054 Multidrug resistance-associated protein/mi... 128 3e-29
CE26370 [Q] KOG0054 Multidrug resistance-associated protein/mito... 128 3e-29
CE23650 [Q] KOG0054 Multidrug resistance-associated protein/mito... 127 4e-29
CE23649 [Q] KOG0054 Multidrug resistance-associated protein/mito... 127 4e-29
7298517 [Q] KOG0054 Multidrug resistance-associated protein/mito... 127 4e-29
YLL015w [Q] KOG0054 Multidrug resistance-associated protein/mito... 127 6e-29
Hs9955960 [Q] KOG0054 Multidrug resistance-associated protein/mi... 127 8e-29
Hs9955958 [Q] KOG0054 Multidrug resistance-associated protein/mi... 127 8e-29
Hs9955954 [Q] KOG0054 Multidrug resistance-associated protein/mi... 127 8e-29
Hs9955952 [Q] KOG0054 Multidrug resistance-associated protein/mi... 127 8e-29
Hs9955950 [Q] KOG0054 Multidrug resistance-associated protein/mi... 127 8e-29
Hs4826838 [Q] KOG0054 Multidrug resistance-associated protein/mi... 127 8e-29
Hs4557481 [Q] KOG0054 Multidrug resistance-associated protein/mi... 126 1e-28
YLL048c [Q] KOG0054 Multidrug resistance-associated protein/mito... 125 3e-28
7299468 [Q] KOG0054 Multidrug resistance-associated protein/mito... 125 3e-28
YGR281w [Q] KOG0054 Multidrug resistance-associated protein/mito... 124 4e-28
CE24285 [Q] KOG0054 Multidrug resistance-associated protein/mito... 123 8e-28
Hs5032101 [Q] KOG0054 Multidrug resistance-associated protein/mi... 122 1e-27
SPAC30.04c [Q] KOG0054 Multidrug resistance-associated protein/m... 122 2e-27
7297379 [Q] KOG0054 Multidrug resistance-associated protein/mito... 122 2e-27
Hs5031915 [Q] KOG0054 Multidrug resistance-associated protein/mi... 121 3e-27
7301758 [Q] KOG0054 Multidrug resistance-associated protein/mito... 121 3e-27
At3g13100 [Q] KOG0054 Multidrug resistance-associated protein/mi... 120 5e-27
At1g30410 [Q] KOG0054 Multidrug resistance-associated protein/mi... 120 5e-27
7297980 [Q] KOG0054 Multidrug resistance-associated protein/mito... 119 1e-26
7298518 [Q] KOG0054 Multidrug resistance-associated protein/mito... 119 2e-26
Hs9955970 [Q] KOG0054 Multidrug resistance-associated protein/mi... 119 2e-26
ECU01g1410 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC s... 118 3e-26
ECU01g0200 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC s... 118 3e-26
At3g13080 [Q] KOG0054 Multidrug resistance-associated protein/mi... 118 4e-26
7300555 [Q] KOG0054 Multidrug resistance-associated protein/mito... 118 4e-26
At3g60160 [Q] KOG0054 Multidrug resistance-associated protein/mi... 116 1e-25
CE09548 [Q] KOG0054 Multidrug resistance-associated protein/mito... 116 1e-25
Hs20539468 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 115 2e-25
At2g47800 [Q] KOG0054 Multidrug resistance-associated protein/mi... 115 2e-25
YHL035c [Q] KOG0054 Multidrug resistance-associated protein/mito... 114 5e-25
SPAC9E9.12c [Q] KOG0054 Multidrug resistance-associated protein/... 114 5e-25
7291275 [Q] KOG0054 Multidrug resistance-associated protein/mito... 113 9e-25
At3g13090 [Q] KOG0054 Multidrug resistance-associated protein/mi... 113 1e-24
Hs6715561 [Q] KOG0054 Multidrug resistance-associated protein/mi... 112 1e-24
At3g62700 [Q] KOG0054 Multidrug resistance-associated protein/mi... 112 1e-24
At3g60970 [Q] KOG0054 Multidrug resistance-associated protein/mi... 112 1e-24
At1g04120 [Q] KOG0054 Multidrug resistance-associated protein/mi... 112 3e-24
CE03119 [Q] KOG0054 Multidrug resistance-associated protein/mito... 111 4e-24
Hs15100172 [Q] KOG0054 Multidrug resistance-associated protein/m... 110 7e-24
At3g59140 [Q] KOG0054 Multidrug resistance-associated protein/mi... 110 1e-23
Hs14211905 [Q] KOG0054 Multidrug resistance-associated protein/m... 109 2e-23
Hs22056689 [U] KOG0058 Peptide exporter ABC superfamily 108 2e-23
Hs15149474 [Q] KOG0054 Multidrug resistance-associated protein/m... 107 6e-23
7297613 [Q] KOG0054 Multidrug resistance-associated protein/mito... 106 1e-22
ECU10g1230 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC s... 101 4e-21
At1g30420 [Q] KOG0054 Multidrug resistance-associated protein/mi... 100 6e-21
ECU11g1200 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC s... 100 1e-20
ECU03g0240 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC s... 99 2e-20
At1g67940 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 99 2e-20
Hs21729888 [Q] KOG0054 Multidrug resistance-associated protein/m... 99 3e-20
Hs21729886 [Q] KOG0054 Multidrug resistance-associated protein/m... 99 3e-20
7301180 [Q] KOG0054 Multidrug resistance-associated protein/mito... 98 5e-20
Hs6995996 [Q] KOG0054 Multidrug resistance-associated protein/mi... 96 2e-19
Hs21729876 [Q] KOG0054 Multidrug resistance-associated protein/m... 92 4e-18
YKR104w [Q] KOG0054 Multidrug resistance-associated protein/mito... 89 2e-17
CE27270 [U] KOG0058 Peptide exporter ABC superfamily 87 1e-16
ECU04g0480 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC s... 84 6e-16
YKR103w [Q] KOG0054 Multidrug resistance-associated protein/mito... 83 2e-15
Hs9955972 [Q] KOG0054 Multidrug resistance-associated protein/mi... 82 2e-15
At5g06530 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 81 6e-15
At3g21090 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 81 6e-15
At4g25750 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 80 8e-15
At5g52860 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 80 1e-14
At2g37010 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 80 1e-14
Hs4506341 [IR] KOG0060 Long-chain acyl-CoA transporter ABC super... 79 2e-14
At1g31770 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 79 2e-14
Hs9955956 [Q] KOG0054 Multidrug resistance-associated protein/mi... 79 3e-14
At1g65410 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 79 3e-14
At5g60740 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 77 1e-13
At3g25620 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 77 1e-13
At1g53270 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 76 2e-13
7295829 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 76 2e-13
7295924 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 76 2e-13
At4g27420 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 75 3e-13
CE25783 [Q] KOG0054 Multidrug resistance-associated protein/mito... 75 3e-13
At1g53390 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 75 5e-13
At1g51500 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 75 5e-13
7296045 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 75 5e-13
At1g51460 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 74 8e-13
CE05669 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 73 1e-12
7295722 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 73 2e-12
At3g13220 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 72 2e-12
At1g17840 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 72 2e-12
Hs8051577 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 72 4e-12
Hs8051575 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 72 4e-12
CE28537 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 72 4e-12
At3g55100 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 72 4e-12
7295821 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 71 5e-12
Hs20143975 [Q] KOG0061 Transporter ABC superfamily (Breast cance... 71 6e-12
CE09192 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 71 6e-12
At3g52310 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 71 6e-12
CE02547 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfa... 70 8e-12
YOL075c [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-1... 70 1e-11
Hs4757850 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 70 1e-11
At2g13610 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 70 1e-11
At5g19410 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 70 1e-11
At5g09930 [R] KOG0927 Predicted transporter (ABC superfamily) 70 1e-11
At3g55130 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 70 1e-11
At3g55110 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 69 2e-11
At2g39350 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 69 2e-11
7297581 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 69 2e-11
At1g54350 [IR] KOG0060 Long-chain acyl-CoA transporter ABC super... 69 2e-11
7294101 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 69 2e-11
Hs4826958 [IR] KOG0060 Long-chain acyl-CoA transporter ABC super... 69 3e-11
Hs10947129 [IR] KOG0060 Long-chain acyl-CoA transporter ABC supe... 69 3e-11
Hs10947127 [IR] KOG0060 Long-chain acyl-CoA transporter ABC supe... 69 3e-11
CE05518 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfa... 68 4e-11
At3g53510 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 68 4e-11
At2g01320 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 68 4e-11
7290367 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 68 4e-11
At3g55090 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 68 6e-11
7293647 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfa... 68 6e-11
YCR011c [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 67 7e-11
At1g71960 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 67 7e-11
Hs10947131 [IR] KOG0060 Long-chain acyl-CoA transporter ABC supe... 67 9e-11
At5g13580 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 67 1e-10
At5g64840 [R] KOG0927 Predicted transporter (ABC superfamily) 66 2e-10
At2g37360 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 65 3e-10
CE09356 [IR] KOG0059 Lipid exporter ABCA1 and related proteins A... 65 4e-10
CE05663 [J] KOG0066 eIF2-interacting protein ABC50 (ABC superfam... 64 8e-10
CE02546 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfa... 64 8e-10
At1g71330 [Q] KOG0054 Multidrug resistance-associated protein/mi... 64 8e-10
7296258 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 64 8e-10
Hs9945308 [I] KOG0064 Peroxisomal long-chain acyl-CoA transporte... 63 2e-09
CE20234 [IR] KOG0059 Lipid exporter ABCA1 and related proteins A... 63 2e-09
At3g53480 [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1... 62 2e-09
At4g33460 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 62 3e-09
At2g37280 [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1... 62 3e-09
Hs17865630 [IR] KOG0059 Lipid exporter ABCA1 and related protein... 61 5e-09
YOR153w [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-1... 61 7e-09
Hs4501849 [IR] KOG0059 Lipid exporter ABCA1 and related proteins... 61 7e-09
YPL058c [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-1... 59 2e-08
YDR011w [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-1... 59 3e-08
SPBC29A3.09c [EJ] KOG0062 ATPase component of ABC transporters w... 59 3e-08
At2g36380 [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1... 59 3e-08
YOR328w [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-1... 59 3e-08
Hs4557876 [IR] KOG0059 Lipid exporter ABCA1 and related proteins... 59 3e-08
Hs17933764 [IR] KOG0059 Lipid exporter ABCA1 and related protein... 59 3e-08
At3g16340 [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1... 59 3e-08
At2g41700 [IR] KOG0059 Lipid exporter ABCA1 and related proteins... 59 3e-08
YDR406w [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-1... 58 4e-08
YFR009w [EJ] KOG0062 ATPase component of ABC transporters with d... 58 6e-08
At1g66950 [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1... 58 6e-08
7295830 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 58 6e-08
YIL013c [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-1... 57 7e-08
Hs7262393 [I] KOG0064 Peroxisomal long-chain acyl-CoA transporte... 57 7e-08
At1g63270 [IR] KOG0059 Lipid exporter ABCA1 and related proteins... 57 7e-08
7295535 [IR] KOG0059 Lipid exporter ABCA1 and related proteins A... 57 7e-08
CE01492 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 57 1e-07
At1g15520 [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1... 57 1e-07
7301693 [IR] KOG0059 Lipid exporter ABCA1 and related proteins A... 57 1e-07
CE00704 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 57 1e-07
At4g15230 [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1... 57 1e-07
Hs11967971 [Q] KOG0061 Transporter ABC superfamily (Breast cance... 56 2e-07
CE29170 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 56 2e-07
ECU03g0390 [Q] KOG0061 Transporter ABC superfamily (Breast cance... 55 3e-07
CE24327 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 55 3e-07
CE22226 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 55 4e-07
At5g14100 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 55 4e-07
Hs16156905 [IR] KOG0059 Lipid exporter ABCA1 and related protein... 55 5e-07
YOR011w [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-1... 54 6e-07
At1g59870 [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1... 54 6e-07
At5g60790 [R] KOG0927 Predicted transporter (ABC superfamily) 54 8e-07
At1g15210 [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1... 54 8e-07
At4g39850 [IR] KOG0060 Long-chain acyl-CoA transporter ABC super... 54 1e-06
HsM5915658 [IR] KOG0059 Lipid exporter ABCA1 and related protein... 53 1e-06
Hs21536376 [IR] KOG0059 Lipid exporter ABCA1 and related protein... 53 1e-06
At2g29940 [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1... 53 1e-06
7292671 [J] KOG0066 eIF2-interacting protein ABC50 (ABC superfam... 53 1e-06
Hs17933762 [IR] KOG0059 Lipid exporter ABCA1 and related protein... 53 2e-06
Hs17933760 [IR] KOG0059 Lipid exporter ABCA1 and related protein... 53 2e-06
Hs17647115 [IR] KOG0059 Lipid exporter ABCA1 and related protein... 53 2e-06
Hs11967969 [Q] KOG0061 Transporter ABC superfamily (Breast cance... 52 3e-06
Hs10947137 [R] KOG0927 Predicted transporter (ABC superfamily) 52 3e-06
At2g26910 [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1... 52 3e-06
SPCC18B5.01c [Q] KOG0065 Pleiotropic drug resistance proteins (P... 51 5e-06
7295524 [IR] KOG0059 Lipid exporter ABCA1 and related proteins A... 51 5e-06
YNR070w [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-1... 51 7e-06
7293943 [IR] KOG0059 Lipid exporter ABCA1 and related proteins A... 51 7e-06
7291597 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 51 7e-06
>YLR188w [U] KOG0058 Peptide exporter ABC superfamily
Length = 695
Score = 844 bits (2181), Expect = 0.0
Identities = 440/669 (65%), Positives = 525/669 (77%), Gaps = 7/669 (1%)
Query: 3 PTMLRLRYIVQNVPLRVNSPSTILRYPINLGKRSPLISFQSRSFARCSIALQAAKKQGKP 62
P +LR ++ + + S ++ + P+ LI + F SI LQ+ QGK
Sbjct: 12 PKLLRSQFASASA---LYSTKSLFKPPMYQKAEINLIIPHRKHFLLRSIRLQSDIAQGKK 68
Query: 63 SLTATVKGLRLSPHDSKASGWQDIKRLFLLAKPETRSMFXXXXXXXXXXXXXXXVPTVIG 122
S T+K LS +SK+SG++DIKRLF+L+KPE++ + VP+VIG
Sbjct: 69 STKPTLK---LSNANSKSSGFKDIKRLFVLSKPESKYIGLALLLILISSSVSMAVPSVIG 125
Query: 123 KLLDIA-RXXXXXXXXXXXTMIFGLTSTQFYTALGGVFVVGALANVGRIVILKVTGERLV 181
KLLD+A ++G T QF+TALG VF++GA+AN RI+ILKVTGERLV
Sbjct: 126 KLLDLASESDGEDEEGSKSNKLYGFTKKQFFTALGAVFIIGAVANASRIIILKVTGERLV 185
Query: 182 ARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGF 241
ARLRTRTMKAAL+QDATFLD NRVGDLISRLSSDA IV+KSVTQN+SDGTRA+IQGFVGF
Sbjct: 186 ARLRTRTMKAALDQDATFLDTNRVGDLISRLSSDASIVAKSVTQNVSDGTRAIIQGFVGF 245
Query: 242 GMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTI 301
GMMSF+SWKLTCVMM+LAPPLG MAL+YG++IRNLSRQLQTSVG LTKV+EEQL+AT+TI
Sbjct: 246 GMMSFLSWKLTCVMMILAPPLGAMALIYGRKIRNLSRQLQTSVGGLTKVAEEQLNATRTI 305
Query: 302 QAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTG 361
QAY GEK E+ RYA EVR VFH+GLKEA+TSG FFG TG VGN A+L+LLL GTSMI++G
Sbjct: 306 QAYGGEKNEVRRYAKEVRNVFHIGLKEAVTSGLFFGSTGLVGNTAMLSLLLVGTSMIQSG 365
Query: 362 LMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPV 421
MTVG+LSSFMMYAV ELMKGAGAAARVFELNDRKPLI PTIGKDPV
Sbjct: 366 SMTVGELSSFMMYAVYTGSSLFGLSSFYSELMKGAGAAARVFELNDRKPLIRPTIGKDPV 425
Query: 422 TLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYD 481
+L K I F +V F+YPTRP+H IF+DLN T++PGEHVC VGPSG GKST+ASLLLRYYD
Sbjct: 426 SLAQKPIVFKNVSFTYPTRPKHQIFKDLNITIKPGEHVCAVGPSGSGKSTIASLLLRYYD 485
Query: 482 IGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISR 541
+ SG I+ G+++IR+FNLRKYRRL+G VQQEP+LF+GTILDNI Y +P E+ + RI R
Sbjct: 486 VNSGSIEFGDEDIRNFNLRKYRRLIGYVQQEPLLFNGTILDNILYCIPPEIAEQDDRIRR 545
Query: 542 AIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALD 601
AIG+ANCTKFLANFPDGLQT VG RG QLSGGQKQRIALARAFLLDP++LILDEATSALD
Sbjct: 546 AIGKANCTKFLANFPDGLQTMVGARGAQLSGGQKQRIALARAFLLDPAVLILDEATSALD 605
Query: 602 SQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPD 661
SQSEE+VA++LQ+R RG TTISIAHR+STI+HS+RVIVL +HG+V ETGSF LIAIP+
Sbjct: 606 SQSEEIVAKNLQRRVERGFTTISIAHRLSTIKHSTRVIVLGKHGSVVETGSFRDLIAIPN 665
Query: 662 SSLNKLLSK 670
S LN LL++
Sbjct: 666 SELNALLAE 674
>YPL270w [U] KOG0058 Peptide exporter ABC superfamily
Length = 820
Score = 491 bits (1263), Expect = e-138
Identities = 279/657 (42%), Positives = 394/657 (59%), Gaps = 12/657 (1%)
Query: 21 SPSTILRYPIN-LGKRSPLI--SFQSRSFARCSIALQAAKKQGKPSLTATVKGLRLSPH- 76
+PS+ P++ L RSP + S +SF RC+ + + + PS + KG S H
Sbjct: 83 TPSSSQLIPLSRLCLRSPAVGKSLILQSF-RCNSS-KTVPETSLPSASPISKGSARSAHA 140
Query: 77 --DSKASGWQDIKRLFLLAKPETRSMFXXXXXXXXXXXXXXXVPTVIGKLLDIARXXXXX 134
SK ++DI RLF+LAK + + + +P VIG +LD +
Sbjct: 141 KEQSKTDDYKDIIRLFMLAKRDWKLLLTAILLLTISCSIGMSIPKVIGIVLDTLKTSSGS 200
Query: 135 XXXXXXTMIFGLTSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALE 194
IF L +F + ++G AN GR ++L++ ER+VARLR +K L
Sbjct: 201 DFFDLKIPIFSLPLYEFLSFFTVALLIGCAANFGRFILLRILSERVVARLRANVIKKTLH 260
Query: 195 QDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCV 254
QDA F D+++VGDLISRL SDA +VS+S+TQ +SDG +A+I G VG GMM +S +L+ +
Sbjct: 261 QDAEFFDNHKVGDLISRLGSDAYVVSRSMTQKVSDGVKALICGVVGVGMMCSLSPQLSIL 320
Query: 255 MMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRY 314
++ PP+ A V+GK+IRN S+ LQ + G+LT+V+EEQLS KT+Q++ E E+ RY
Sbjct: 321 LLFFTPPVLFSASVFGKQIRNTSKDLQEATGQLTRVAEEQLSGIKTVQSFVAEGNELSRY 380
Query: 315 ADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMY 374
+R +F VG A T+ FF T +G+++ L +L G+ ++ +++GDL++FM+Y
Sbjct: 381 NVAIRDIFQVGKTAAFTNAKFFTTTSLLGDLSFLTVLAYGSYLVLQSQLSIGDLTAFMLY 440
Query: 375 AVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVK 434
E+M+GAGAA+R+FEL DRKP I PT+G + I F V
Sbjct: 441 TEYTGNAVFGLSTFYSEIMQGAGAASRLFELTDRKPSISPTVG-HKYKPDRGVIEFKDVS 499
Query: 435 FSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNI 494
FSYPTRP IF++LNF + PG VCIVGPSG GKST+A LLLRYY+ +G I + N +I
Sbjct: 500 FSYPTRPSVQIFKNLNFKIAPGSSVCIVGPSGRGKSTIALLLLRYYNPTTGTITIDNQDI 559
Query: 495 RDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLAN 554
N + RR +G+VQQEP+L SGTI DNITY + +E R Q C F+
Sbjct: 560 SKLNCKSLRRHIGIVQQEPVLMSGTIRDNITYGLTYTPTKEEIR--SVAKQCFCHNFITK 617
Query: 555 FPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSL-Q 613
FP+ T +GP GT LSGGQKQRIA+ARA + P+ILILDEATSALD +SE + + Q
Sbjct: 618 FPNTYDTVIGPHGTLLSGGQKQRIAIARALIKKPTILILDEATSALDVESEGAINYTFGQ 677
Query: 614 QRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
++ T +SIAHR+STI+ S VIVL G+V E G F +L A P S+L++LL++
Sbjct: 678 LMKSKSMTIVSIAHRLSTIRRSENVIVLGHDGSVVEMGKFKELYANPTSALSQLLNE 734
>SPBC9B6.09c [U] KOG0058 Peptide exporter ABC superfamily
Length = 726
Score = 459 bits (1180), Expect = e-129
Identities = 251/586 (42%), Positives = 367/586 (61%), Gaps = 13/586 (2%)
Query: 85 DIKRLFLLAKPETRSMFXXXXXXXXXXXXXXXVPTVIGKLLDIARXXXXXXXXXXXTMIF 144
++ RLF LA+ + + F +P ++GK+LD T I
Sbjct: 143 NVFRLFTLARGQGWNFFIAGSLLLVSSGVTMSIPYIVGKILDAG-----SSGDSSVTHIM 197
Query: 145 GLTSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNR 204
G+ S FY L G+F +G+ N GRI+ L++ ER+V+RLR R + D F D ++
Sbjct: 198 GIPSGTFYIGLLGLFFLGSACNFGRIITLRLLSERIVSRLRARLFAKCMSLDGAFFDFHK 257
Query: 205 VGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGV 264
GDLISRL++D+ IV KS++ LSDG R+ + G GMM ++S +LT M L+ PP+ +
Sbjct: 258 HGDLISRLTTDSSIVGKSLSMYLSDGLRSSVSAIAGIGMMLYVSMRLTGYMSLIVPPIAL 317
Query: 265 MALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHV 324
A YG+ +R LSR Q ++G+LT+VSEE+L+ +T QA+ GE++E++RY D +R +F +
Sbjct: 318 GAFFYGEYVRKLSRTTQDALGDLTRVSEEKLANVRTTQAFLGERQEVNRYNDYIRNLFVL 377
Query: 325 GLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXX 384
+EA SG FFG TGF+GN ++A+L G M+ G +TVG LSSF++Y V
Sbjct: 378 AKREAFASGIFFGSTGFLGNATVIAILALGGRMVAAGDITVGQLSSFLLYTVYAGGSIVG 437
Query: 385 XXXXXXELMKGAGAAARVFELNDRKPLIHPTIG-KDPVTLENKSIHFNHVKFSYPTRPQH 443
++MKG GAA+R+FEL D KP I PT+G PVT+ + F +V F+YPTRP
Sbjct: 438 LSGCFTDIMKGLGAASRLFELLDAKPKIAPTVGIPVPVTVGKAILSFRNVGFAYPTRPSA 497
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYR 503
IF++L+F + PG +V IV PSGGGKST++ LLLR+Y SG+I +I +N+ ++R
Sbjct: 498 SIFDNLSFDIHPGTNVAIVAPSGGGKSTISQLLLRFYAPSSGKILADGVDISTYNVHQWR 557
Query: 504 RLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTV 563
G+V QEP+LFSGTI +NI Y + I A +ANC+ F+ +FP+ T V
Sbjct: 558 SHFGLVGQEPVLFSGTIGENIAYGKSNA---SQEEIEDAAKRANCS-FVLSFPEKWSTQV 613
Query: 564 GPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQ-RSARGKTT 622
G RG QLSGGQKQRIA+ARA L +P+ LILDEATSALD ++E +V +++Q R TT
Sbjct: 614 GTRGLQLSGGQKQRIAIARALLRNPAFLILDEATSALDGEAEVMVDKTIQSLMHNRSMTT 673
Query: 623 ISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLL 668
I+IAH+++TI+ + ++IV+ G V E GSF++L + P ++ KL+
Sbjct: 674 ITIAHKLATIRRADQIIVVG-DGKVLEQGSFERL-SRPGTNFYKLM 717
>Hs9961244 [U] KOG0058 Peptide exporter ABC superfamily
Length = 738
Score = 409 bits (1050), Expect = e-113
Identities = 232/595 (38%), Positives = 345/595 (56%), Gaps = 17/595 (2%)
Query: 80 ASGWQDIKRLFLLAKPETRSMFXXXXXXXXXXXXXXXVPTVIGKLLDIARXXXXXXXXXX 139
A+G + ++L LA PE R + P +GK++D+
Sbjct: 151 AAGLPEARKLLGLAYPERRRLAAAVGFLTMSSVISMSAPFFLGKIIDVI--------YTN 202
Query: 140 XTMIFGLTSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATF 199
T+ + T+ L VF+ GA AN R+ +++ +G+R+V RLRT + L Q+ F
Sbjct: 203 PTVDYSDNLTRLCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAF 262
Query: 200 LDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLA 259
D R G+LI+RLSSD ++ +SVT+NLSDG RA Q VG MM F+S L ++ +
Sbjct: 263 FDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVGISMMFFVSPNLATFVLSVV 322
Query: 260 PPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVR 319
PP+ ++A++YG+ +R L++ Q S+ + T+++EE++ +T++A+ E EI +YA +V
Sbjct: 323 PPVSIIAVIYGRYLRKLTKVTQDSLAQATQLAEERIGNVRTVRAFGKEMTEIEKYASKVD 382
Query: 320 KVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXX 379
V + KEA+ FFG TG GN+ +L++L G ++ + MTVG+LSSF+MYA
Sbjct: 383 HVMQLARKEAVARAGFFGATGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVG 442
Query: 380 XXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKS----IHFNHVKF 435
ELMKG GA R++EL +R+P + G V L KS + F +V F
Sbjct: 443 ISIGGLSSFYSELMKGLGAGGRLWELLEREPKLPFNEG---VILNEKSFQGALEFKNVHF 499
Query: 436 SYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIR 495
+YP RP+ IF+D + ++ G +VGPSG GKSTV SLLLR Y+ SG I L +IR
Sbjct: 500 AYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYNPASGTISLDGHDIR 559
Query: 496 DFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANF 555
N R +G V QEP+LFS +I +NI Y I R AN F+ NF
Sbjct: 560 QLNPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVAFIRNF 619
Query: 556 PDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQR 615
P G T VG +G LSGGQKQRIA+ARA L +P IL+LDEATSALD+++E +V ++L R
Sbjct: 620 PQGFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEAL-DR 678
Query: 616 SARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
G+T + IAHR+STI++++ V VL++ G + E G ++L++ P+ KL++K
Sbjct: 679 LMDGRTVLVIAHRLSTIKNANMVAVLDQ-GKITEYGKHEELLSKPNGIYRKLMNK 732
>CE16149 [U] KOG0058 Peptide exporter ABC superfamily
Length = 733
Score = 391 bits (1005), Expect = e-108
Identities = 232/595 (38%), Positives = 346/595 (57%), Gaps = 8/595 (1%)
Query: 79 KASGWQDIKRLFLLAKPETRSMFXXXXXXXXXXXXXXXVPTVIGKLLDI-ARXXXXXXXX 137
K + W+D+K + LA P + P V+GKL+D
Sbjct: 133 KNASWKDLKAILSLAGPYKWRIMLGISFLGISSSIFLFTPRVLGKLIDEWDETKQDKMDP 192
Query: 138 XXXTMIFGLTSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDA 197
++ + AL GVF++GA+A RI + G+ ++ LR + L QD
Sbjct: 193 NDKALLLARFFKENPIALAGVFMLGAIAIAARIYCMHTAGQLVINDLRKSVFNSVLRQDM 252
Query: 198 TFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMML 257
F D N+VG+++SRLS+DA IV SV+ NLSDG RA+I F G+M + S + V+ +
Sbjct: 253 AFFDKNKVGEIVSRLSTDALIVGYSVSMNLSDGARALITCFGSGGLMVYTSLAMCKVIFV 312
Query: 258 LAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADE 317
+ P + V+GK R + +Q +V +V+ E+LS+ +T++ E+KE+ Y+D+
Sbjct: 313 VVPVIVGTFAVFGKLQRKYTLMMQEAVAGANQVATERLSSVRTVRMLVAERKELAAYSDK 372
Query: 318 VRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVX 377
+ +++ + KE L G FG F G +AL ++L G+++I GL+T G+LSSF +YAV
Sbjct: 373 INEIWQISKKEGLAKGFMFGSFQFTGYLALSSILFYGSNLISQGLLTYGELSSFCLYAVL 432
Query: 378 XXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSY 437
ELMKG GA++R+FEL +R+P I P G + +I F HV F Y
Sbjct: 433 SAGSLSAMSGFYLELMKGLGASSRLFELKNREPRI-PLEGGVQIGNVKDTIRFEHVAFGY 491
Query: 438 PTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDF 497
R +F +++F V G+ +VG SG GKST+ASLLLR YD SG I + +++D
Sbjct: 492 ADRDP--LFHNISFDVPAGKITAVVGSSGSGKSTIASLLLRLYDPTSGRILVDGTDLKDI 549
Query: 498 NLRKYRRLLGVVQQEPMLFSGTILDNITY-AVPQELVNDETRISRAIGQANCTKFLANFP 556
+ +RR +G V QEP+LFS TI +NI Y ++ E V D +S A Q+N +F++ FP
Sbjct: 550 DPSYWRRHIGTVGQEPVLFSTTIKENIIYGSLEPENVTDAEIVS-AADQSNADEFISRFP 608
Query: 557 DGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRS 616
T VG G+ LSGGQKQRIA+ARA + P+ILI+DEATSALD+ SE +V +L +
Sbjct: 609 IKYDTKVGEHGSTLSGGQKQRIAIARALVNKPNILIMDEATSALDASSEYLVRIALNKLL 668
Query: 617 ARGKTTIS-IAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
A K T+ IAHR+STI+H+ +++V++R G+VAE+GS+D+LIAIPD KL+ K
Sbjct: 669 ANSKQTVMIIAHRLSTIKHADQIVVVDR-GSVAESGSYDELIAIPDGIFRKLVEK 722
>7290042 [U] KOG0058 Peptide exporter ABC superfamily
Length = 643
Score = 345 bits (884), Expect = 2e-94
Identities = 216/647 (33%), Positives = 341/647 (52%), Gaps = 35/647 (5%)
Query: 44 RSFARCSIALQAAKKQGKPSLTATVKGLRLSPHDSKASGWQDIKRLFLLAKPETRSMFXX 103
R FA+ S L K P T G + P K G RL L K E +
Sbjct: 3 RGFAQSSKWLARNAKANLP----TAVGAGIVPAPVKM-GRSQYGRLLSLTKSEKWVLTAG 57
Query: 104 XXXXXXXXXXXXXVPTVIGKLLDIARXXXXXXXXXXXTMIFGLTSTQFYTALGGVFVVGA 163
VP +GK++D+ + ++ L G+FV+G
Sbjct: 58 IGCLVVSSAITMSVPLFLGKVIDVVFNKSGMDSAAMAKL------GEYSVLLFGIFVLGG 111
Query: 164 LANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSV 223
AN R+ + R+V LR+R ++ L Q+ + D G+LI+RLS+D +V S+
Sbjct: 112 FANFARVHLFGNAALRIVRSLRSRLYRSMLMQEVGWFDTKGTGELINRLSNDTLMVGTSL 171
Query: 224 TQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTS 283
+QN+SDG R+V VG GMM + S +L V L+ P + MA+VYG+ +R +++
Sbjct: 172 SQNVSDGLRSVAMIGVGTGMMIYTSPQLAAVSALVVPAMAGMAIVYGRYVRRITKVELDK 231
Query: 284 VGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGV----- 338
E+ K +EE+ KT++ +C E++E+ + ++ + +G KE FFG+
Sbjct: 232 YAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYKETRARAIFFGLVRPKG 291
Query: 339 ---------------TGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXX 383
TGF GN ++++L G +++ +T+G L++FM+YA
Sbjct: 292 KVLRKIIKICYPLFQTGFCGNFIIISVLYYGGTLVLQDSLTIGALTAFMLYAGYVAISMN 351
Query: 384 XXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQH 443
+L KG GA+ R++E+ DR+ I G P+ + F +V F++PTRP+
Sbjct: 352 GLSNFYSQLNKGIGASERIWEILDRECSIPIDKGVVPLEKPVGEVGFQNVFFTFPTRPES 411
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYR 503
+ D + + PG +VG SG GK+T+A L+LR YD G + L ++R N + R
Sbjct: 412 AVLTDFSLNLMPGTTTAVVGRSGSGKTTIALLMLRLYDPQGGTVHLDGIDLRTVNPQWLR 471
Query: 504 RLLGVVQQEPMLFSGTILDNITY-AVPQELVNDETRISRAIGQANCTKFLANFPDGLQTT 562
+G V QEP+LFS +I +NI Y A P E + E R+ + I AN ++F PDGL T
Sbjct: 472 NNIGAVSQEPVLFSCSIRENILYGANPGETPSPE-RLQQVIEDANVSQFTDQLPDGLDTL 530
Query: 563 VGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTT 622
VG RG LSGGQKQR+A+ARA + +P+ILILDEATSALD+ SE +V +L +G+T
Sbjct: 531 VGQRGMMLSGGQKQRVAIARALIKNPAILILDEATSALDAVSENLVQNAL-DNLIQGRTV 589
Query: 623 ISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLS 669
++IAHR+STI+++ ++ VL+ G + E GS+++L+ I + +L++
Sbjct: 590 LTIAHRLSTIRNADQIAVLS-DGKIVEQGSYNELMGIQEGVFRELVA 635
>At5g39040 [U] KOG0058 Peptide exporter ABC superfamily
Length = 639
Score = 335 bits (860), Expect = 1e-91
Identities = 198/602 (32%), Positives = 316/602 (51%), Gaps = 12/602 (1%)
Query: 58 KQGKPSLTATVKGLRLSPHDSKASGWQDIKRLFLLAKPETRSMFXXXXXXXXXXXXXXXV 117
++ KP + GL H + R+F LAKP+ + V
Sbjct: 29 QEDKPKANGSENGLNDLEHGVVEAANVGFGRVFALAKPDAGKLVIGTIALLIGSTTNLLV 88
Query: 118 PTVIGKLLDIARXXXXXXXXXXXTMIFGLTSTQFYTALGGVFVVGALANVGRIVILKVTG 177
P G ++DI ++I + + V+G++ R +
Sbjct: 89 PKFGGMIIDIVSRDVKTPEQQTESLIAVRNAVVIILL---IVVIGSICTALRAWLFNSAS 145
Query: 178 ERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQG 237
ER+VARLR + + Q+ F D + G+L+SRLS D I+ + T NLS+ R V
Sbjct: 146 ERVVARLRKDLFRHLMHQEIAFYDVTKTGELLSRLSEDTQIIKNAATTNLSEALRNVTTA 205
Query: 238 FVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSA 297
+G G M SWKLT L P + V +G+ +R LS Q + ++EE A
Sbjct: 206 LIGVGFMFTSSWKLT-----LVPVISVAVKQFGRYLRELSHTTQAAAAVAASIAEESFGA 260
Query: 298 TKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSM 357
+T++++ E + +Y+ +V + +GLK+A+ G FFG ++++ ++ G +
Sbjct: 261 VRTVRSFAKESYMVSQYSKKVDETLKLGLKQAVLVGLFFGGLNAAFTLSVITVVSYGAYL 320
Query: 358 IKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIG 417
G MTVG L+SF++Y++ MK AGA+ RVF++ DR + +
Sbjct: 321 TIYGSMTVGALTSFILYSLTVGSSVSSLSSLYTTAMKAAGASRRVFQILDRVSSMSSSGD 380
Query: 418 KDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLL 477
K PV + + N V F+YP+RP H I + ++ + PG V +VGPSGGGK+T+A+L+
Sbjct: 381 KCPVGNPDGDVELNDVWFAYPSRPSHMILKGISLRLTPGSKVALVGPSGGGKTTIANLIE 440
Query: 478 RYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDET 537
R+YD G+I L ++ + + + + + +V QEP+LF+ ++ +NI Y E T
Sbjct: 441 RFYDPLKGKILLNGVSLMEISHQYLHKQISIVSQEPILFNCSVEENIAYGFDGEA--SFT 498
Query: 538 RISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEAT 597
I A AN +F+ FPD T VG RG +LSGGQKQRIA+ARA L +PS+L+LDEAT
Sbjct: 499 DIENAAKMANAHEFIEAFPDKYNTVVGERGLRLSGGQKQRIAIARALLTNPSVLLLDEAT 558
Query: 598 SALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
SALD++SE +V ++ A G+T + IAHR+ST++ + V V++ G VAE G+ D+L+
Sbjct: 559 SALDAESEYLVQDAMDSLMA-GRTVLVIAHRLSTVKTADCVAVIS-DGEVAEKGTHDELL 616
Query: 658 AI 659
++
Sbjct: 617 SL 618
>CE15650 [U] KOG0058 Peptide exporter ABC superfamily
Length = 586
Score = 311 bits (798), Expect = 2e-84
Identities = 183/551 (33%), Positives = 300/551 (54%), Gaps = 12/551 (2%)
Query: 117 VPTVIGKLLDIARXXXXXXXXXXXTMIFGLTSTQFYT----ALGGVFVVGALANVGRIVI 172
+P ++GKL+D +F + +++ +L G+ +GALA ++
Sbjct: 11 IPRILGKLID---QFDSNTGVQKAEEVFTMKIAKYFKEQPMSLVGLLAIGALATAAKVYC 67
Query: 173 LKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTR 232
L++ G +V LR + + QD TF D N VG++ SR ++D IV SV+ +L G R
Sbjct: 68 LQIAGVNIVGSLRKMVYSSIIRQDMTFFDKNMVGEIGSRHAADTVIVGYSVSSSLRAGVR 127
Query: 233 AVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSE 292
AV+ G GMM S +L+ V L AP + + ++G+ + + QLQ ++ + +
Sbjct: 128 AVLVGVGSIGMMLMTSLELSTVSFLTAPIVMGIFKMFGRVQQQCTWQLQEVAADVNQTAI 187
Query: 293 EQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLL 352
E+++ KTI+ E++ I Y + V + EAL G+ G F G A ++L
Sbjct: 188 ERMANMKTIRMLSAEQQSIDEYCKKGELVLDISKTEALAKGSLIGSFQFTGYSAFSSILF 247
Query: 353 TGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLI 412
G+ +I TG +T G+LSSF +YAV E+MKG GA++R+ EL + +P++
Sbjct: 248 YGSHLINTGHITYGELSSFCLYAVLAAASLSNISGFYNEVMKGLGASSRLLELKNAQPIM 307
Query: 413 HPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTV 472
+ G + SI F +V F+Y R + E+++F + G+ ++GPSG GKS++
Sbjct: 308 NLNSGIKKTDI-TTSIQFENVSFAYAGRKK--TLENISFDIPRGKITAVIGPSGSGKSSI 364
Query: 473 ASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQEL 532
A+L+LR YD G + + ++RD N +R +G V QEP+LF+ +I +NI
Sbjct: 365 ANLMLRLYDPADGRVTVDGVDLRDLNATTWRHAIGTVGQEPVLFTCSIRENILMGTEHPE 424
Query: 533 VNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILI 592
+ + A AN F+ F +G +T VG G +LSGGQKQRIA+ARA + P I+I
Sbjct: 425 KVSQYELEEAAQLANALDFIQGFENGFETMVGEHGCKLSGGQKQRIAIARALISKPKIMI 484
Query: 593 LDEATSALDSQSEEVVAQSLQQ-RSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETG 651
LDEATSALD+ S+ ++ +L T + IAHR++T+Q + +V+ +NR G + G
Sbjct: 485 LDEATSALDATSDYLIRMTLDNLLKNHNLTVLVIAHRLATMQQADQVVYVNR-GRIEGQG 543
Query: 652 SFDKLIAIPDS 662
+FD+++ I +S
Sbjct: 544 TFDEMMKIQNS 554
>Hs9955966 [U] KOG0058 Peptide exporter ABC superfamily
Length = 766
Score = 296 bits (759), Expect = 6e-80
Identities = 183/586 (31%), Positives = 315/586 (53%), Gaps = 22/586 (3%)
Query: 75 PHDSKASGWQDIKRLFLLAKPETRSMFXXXXXXXXXXXXXXXVPTVIGKLLDIARXXXXX 134
P +ASG +++L KP+ + +P G+ +D
Sbjct: 164 PPPEQASG-ATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSM 222
Query: 135 XXXXXXTMIFGLTSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALE 194
+I L A+G F G + ++ RL RLR ++ +
Sbjct: 223 DQFSTAVVIVCLL------AIGSSFAAGIRGGIFTLIFA-----RLNIRLRNCLFRSLVS 271
Query: 195 QDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQ--GFVGFGMMSFISWKLT 252
Q+ +F D NR GDLISRL+SD +VS V+QN++ R ++ G V F M +SW+L+
Sbjct: 272 QETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVF--MFSLSWQLS 329
Query: 253 CVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIH 312
V + P + +++ +YGK + LS+++Q ++ + +EE +SA KT++++ E++E
Sbjct: 330 LVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAE 389
Query: 313 RYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFM 372
Y ++++V+ + KEA + +G V +++L G ++ +G MT G+L +F+
Sbjct: 390 VYLRKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISGQMTSGNLIAFI 449
Query: 373 MYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNH 432
+Y LM+G GAA +VFE DR+P + P LE + + F +
Sbjct: 450 IYEFVLGDCMESVGSVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGR-VDFEN 508
Query: 433 VKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGND 492
V F+Y TRP + ++++F++ PG+ +VGPSG GKS+ ++L +Y + G + L
Sbjct: 509 VTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGK 568
Query: 493 NIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFL 552
I ++ + R++ +V QEP+LF+ +I DNI+Y +P + A +AN F+
Sbjct: 569 PISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFE---MVVEAAQKANAHGFI 625
Query: 553 ANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSL 612
DG T G +G QLSGGQKQR+A+ARA + +P +LILDEATSALD++SE ++ Q++
Sbjct: 626 MELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAI 685
Query: 613 QQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
+ + T + IAHR+ST++H+ ++VL++ G V + G+ +L+A
Sbjct: 686 -HGNLQKHTVLIIAHRLSTVEHAHLIVVLDK-GRVVQQGTHQQLLA 729
>Hs6005804 [U] KOG0058 Peptide exporter ABC superfamily
Length = 718
Score = 290 bits (742), Expect = 5e-78
Identities = 187/544 (34%), Positives = 290/544 (52%), Gaps = 14/544 (2%)
Query: 117 VPTVIGKLLDIARXXXXXXXXXXXTMIFGLTSTQFYTALGGVFVVGALANVGRIVILKVT 176
+P ++G+L+ + T S T L ++ V L G +V+L
Sbjct: 148 IPLLLGQLVKVVAKYTRDHVGSFMT-----ESQNLSTHLLILYGVQGLLTFGYLVLLSHV 202
Query: 177 GERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQ 236
GER+ +R + L Q+ TF D N+ G L+SRL++D S +S G R+ Q
Sbjct: 203 GERMAVDMRRALFSSLLRQNITFFDANKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCSQ 262
Query: 237 GFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLS 296
+S +S +LT ++M+ P L + + G +R LSRQ Q + V++E L
Sbjct: 263 VAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSGLRKLSRQCQEHIARAMGVADEALG 322
Query: 297 ATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTS 356
+T++A E++E RY E+ + F G++ N +L L G S
Sbjct: 323 NVRTVRALAMEQREEERYGAELEACRCRAEELGRGIALFQGLSNIAFNCMVLGTLFIGGS 382
Query: 357 MIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTI 416
++ +T GDL SF++ + ++++G A ARVFE P I P
Sbjct: 383 LVAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARVFEYMALNPCI-PLS 441
Query: 417 GKDPVTLENK--SIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVAS 474
G V E S+ F +V FSYP RP + +D T+ PG+ V +VG SGGGK+TVAS
Sbjct: 442 GGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLTLPPGKIVALVGQSGGGKTTVAS 501
Query: 475 LLLRYYDIGSGEIKLGNDNIRDFNLRKYR-RLLGVVQQEPMLFSGTILDNITYAVPQELV 533
LL R+YD +G + L ++R + R +++G + QEP+LF TI++NI + +L
Sbjct: 502 LLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEPVLFGTTIMENIRFG---KLE 558
Query: 534 NDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILIL 593
+ + A +AN +F+ +FP+G T VG RGT LSGGQKQR+A+ARA + P++LIL
Sbjct: 559 ASDEEVYTAAREANAHEFITSFPEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLIL 618
Query: 594 DEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSF 653
DEATSALD++SE VV ++L + SA G+T + IAHR+ST++ + IV+ G V E G+
Sbjct: 619 DEATSALDAESERVVQEALDRASA-GRTVLVIAHRLSTVR-GAHCIVVMADGRVWEAGTH 676
Query: 654 DKLI 657
++L+
Sbjct: 677 EELL 680
>CE07240 [U] KOG0058 Peptide exporter ABC superfamily
Length = 761
Score = 286 bits (733), Expect = 6e-77
Identities = 162/488 (33%), Positives = 271/488 (55%), Gaps = 7/488 (1%)
Query: 183 RLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFG 242
R+R + + QD F D + GD +SRL+SD +S +V+ N++ R +
Sbjct: 271 RIRLDLFTSLIRQDIAFYDTAKTGDTMSRLTSDCQTISSTVSTNVNVFMRNGVMLIGALA 330
Query: 243 MMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQ 302
M +SW+L V + P +G + Y +S +LQ ++ E +++EE +S +T++
Sbjct: 331 FMILMSWRLAMVTFIAVPLVGFITKAYSSFYDKISEKLQQTIAETNQMAEEVVSTMRTVR 390
Query: 303 AYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGL 362
++ EKKE+ R+ D + V K+++ + F N L+A+L G ++ TG
Sbjct: 391 SFACEKKELKRFEDRLSSTLSVNRKKSIAYLFYTWNNEFCDNAILVAVLFYGGHLVMTGK 450
Query: 363 MTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVT 422
M L +F++Y + LM+ GA+ +VF+L +RKP + P
Sbjct: 451 MEKEQLITFLLYQMQLGENLYYLSYVMSGLMEAVGASRKVFDLMNRKPQFELDGMQRPFV 510
Query: 423 LENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDI 482
N +I F+HV F+YP+RP + + +DL +++ GE V +VGPSGGGKS++ SL+ +Y+
Sbjct: 511 --NGNITFSHVGFTYPSRPNNPVLKDLTLSIKSGETVALVGPSGGGKSSIVSLIEHFYEP 568
Query: 483 GSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRA 542
G + L I+D N Y + + +V QEP+L++G++ NI Y +D S+
Sbjct: 569 DEGSVTLDGVPIKDINHVYYHQKVALVAQEPVLYNGSVRHNILYGCDFATEDDMLNASK- 627
Query: 543 IGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDS 602
AN F+ G T G +G Q+SGGQKQRIA+ARA + +P++LILDEATSALD+
Sbjct: 628 --MANVHDFVMELEKGYDTNCGEKGVQMSGGQKQRIAIARALVRNPAVLILDEATSALDT 685
Query: 603 QSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDS 662
+SE +V Q+L R A+ +T I +AHR+STI+ ++++ V+ + G + + G+ +L+ D
Sbjct: 686 ESEALVQQAL-SRCAQERTVIIVAHRLSTIEKANKIAVIVK-GCLVQMGTHTELMTDTDG 743
Query: 663 SLNKLLSK 670
L+S+
Sbjct: 744 MYYSLVSR 751
>At1g27940 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1245
Score = 280 bits (716), Expect = 5e-75
Identities = 177/486 (36%), Positives = 275/486 (56%), Gaps = 11/486 (2%)
Query: 176 TGERLVARLRTRTMKAALEQDATFLDHN-RVGDLISRLSSDAGIVSKSVTQNLSDGTRAV 234
TGER ARLR +K+ L +D TF D R +LI +SSDA +V ++ R +
Sbjct: 117 TGERQTARLRINYLKSILAKDITFFDTEARDSNLIFHISSDAILVQDAIGDKTDHVLRYL 176
Query: 235 IQGFVGFGMMSFIS-WKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEE 293
Q GF ++ F+S W+LT + + + P + + Y + +S + +T+ + KV+EE
Sbjct: 177 SQFIAGF-VIGFLSVWQLTLLTLGVVPLIAIAGGGYAIVMSTISEKSETAYADAGKVAEE 235
Query: 294 QLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLT 353
+S +T+ A+ GE+K + Y++ ++K +G + L G G+T + A LL
Sbjct: 236 VMSQVRTVYAFVGEEKAVKSYSNSLKKALKLGKRSGLAKGLGVGLTYSLLFCAWALLLWY 295
Query: 354 GTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIH 413
+ +++ G + ++ + + KG AAA +F +
Sbjct: 296 ASLLVRHGKTNGAKAFTTILNVIFSGFALGQAAPSLSAIAKGRVAAANIFRMIGNNNSES 355
Query: 414 PTIGKDPVTLENKS--IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKST 471
+ TL+N + I F V F+YP+RP + +FE+L+FT+R G+ VGPSG GKST
Sbjct: 356 SQRLDEGTTLQNVAGRIEFQKVSFAYPSRP-NMVFENLSFTIRSGKTFAFVGPSGSGKST 414
Query: 472 VASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQE 531
+ S++ R+Y+ SGEI L ++I+ L+ +R LG+V QEP LF+ TI NI +E
Sbjct: 415 IISMVQRFYEPNSGEILLDGNDIKSLKLKWFREQLGLVSQEPALFATTIASNILLG--KE 472
Query: 532 LVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSIL 591
N + +I A AN F+ + P+G T VG GTQLSGGQKQRIA+ARA L +P IL
Sbjct: 473 NANMD-QIIEAAKAANADSFIKSLPNGYNTQVGEGGTQLSGGQKQRIAIARAVLRNPKIL 531
Query: 592 ILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETG 651
+LDEATSALD++SE++V Q+L + +TTI +AHR+STI++ +++VL R G V ETG
Sbjct: 532 LLDEATSALDAESEKIVQQALDNVMEK-RTTIVVAHRLSTIRNVDKIVVL-RDGQVRETG 589
Query: 652 SFDKLI 657
S +L+
Sbjct: 590 SHSELM 595
Score = 266 bits (679), Expect = 1e-70
Identities = 167/496 (33%), Positives = 257/496 (51%), Gaps = 8/496 (1%)
Query: 177 GERLVARLRTRTMKAALEQDATF--LDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAV 234
GERL +R+R A L + + LD N G L S L++DA +V ++ LS + +
Sbjct: 750 GERLTSRVRLSLFSAILSNEIGWFDLDENNTGSLTSILAADATLVRSALADRLSTIVQNL 809
Query: 235 IQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQ 294
+ F SW++ V+ P L +L ++ + T V+ E
Sbjct: 810 SLTVTALALAFFYSWRVAAVVTACFPLLIAASLTEQLFLKGFGGDYTRAYSRATSVAREA 869
Query: 295 LSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTG 354
++ +T+ AY EK+ ++ E+ K SG +G++ F+ + L
Sbjct: 870 IANIRTVAAYGAEKQISEQFTCELSKPTKNAFVRGHISGFGYGLSQFLAFCSYALGLWYV 929
Query: 355 TSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHP 414
+ +I GD M + +++KG A VF + R+ I P
Sbjct: 930 SVLINHKETNFGDSIKSFMVLIVTAFSVSETLALTPDIVKGTQALGSVFRVLHRETKISP 989
Query: 415 TIGKDPVTLENKS-IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVA 473
+ + K I F +V F YPTRP+ IF++LN V G+ + +VGPSG GKSTV
Sbjct: 990 DQPNSRMVSQVKGDIEFRNVSFVYPTRPEIDIFKNLNLRVSAGKSLAVVGPSGSGKSTVI 1049
Query: 474 SLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELV 533
L++R+YD +G + + +I+ NLR R+ L +VQQEP LFS TI +NI Y
Sbjct: 1050 GLIMRFYDPSNGNLCIDGQDIKTLNLRSLRKKLALVQQEPALFSTTIYENIKYGNENA-- 1107
Query: 534 NDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILIL 593
E I A AN +F+ +G +T G +G QLSGGQKQR+A+ARA L DPS+L+L
Sbjct: 1108 -SEAEIMEAAKAANAHEFIIKMEEGYKTHAGDKGVQLSGGQKQRVAIARAVLKDPSVLLL 1166
Query: 594 DEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSF 653
DEATSALD+ SE++V ++L + +G+TT+ +AHR+STI+ + V VL++ G V E GS
Sbjct: 1167 DEATSALDTSSEKLVQEAL-DKLMKGRTTVLVAHRLSTIRKADTVAVLHK-GRVVEKGSH 1224
Query: 654 DKLIAIPDSSLNKLLS 669
+L++IP+ +L S
Sbjct: 1225 RELVSIPNGFYKQLTS 1240
>7292782 [U] KOG0058 Peptide exporter ABC superfamily
Length = 761
Score = 279 bits (714), Expect = 9e-75
Identities = 184/576 (31%), Positives = 295/576 (50%), Gaps = 9/576 (1%)
Query: 85 DIKRLFLLAKPETRSMFXXXXXXXXXXXXXXXVPTVIGKLLDIARXXXXXXXXXXXTMIF 144
D KRL+ +P + +P ++G L++ F
Sbjct: 118 DWKRLWTYLEPHLWELIGAVCAALIVAYINIRIPNLLGDLVNTLARYANTYVMDPINNSF 177
Query: 145 GLTSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNR 204
++ + L ++++ + I +L GE++ A++R + QD F D NR
Sbjct: 178 VKDVSKPASNLLSLYMLQSGFTFMYIYLLSRVGEQMAAKMRQDLFTQIVVQDIAFFDENR 237
Query: 205 VGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGV 264
G+L++RL++D S Q +S G R+ Q +G + F+ + L + P V
Sbjct: 238 TGELVNRLTADVQDFKTSFKQFVSQGLRSAAQ-LIGGSISLFMISPHMAAIALASVPCVV 296
Query: 265 MALVY-GKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFH 323
M + Y GK++R+LS+ Q T V EE LS +T+++ E +E+ + E +
Sbjct: 297 MFMTYLGKKLRSLSKSSQAQAERATGVCEEALSNIRTVRSSACEYREMQLFEAETNEAAR 356
Query: 324 VGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXX 383
+ K F G+T F N +L+ L G ++ T ++ G L +F++ +
Sbjct: 357 LAQKLGYGIAIFQGLTNFFLNTLVLSTLFMGGHLMSTESLSPGALMAFLVASQGVQRSLA 416
Query: 384 XXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGK-DPVTLENKSIHFNHVKFSYPTRPQ 442
+++G A +RVFE +P + G P + I F +V F+YP +P
Sbjct: 417 QGSILLGTMIRGMSAGSRVFEFLSLQPQVELLRGYIIPQERLHGEIRFENVSFAYPMQPD 476
Query: 443 HHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKY 502
H + +D + T+RPG+ V +VG SG GKST+ASL+ R+Y+ +G IKL + D +
Sbjct: 477 HLVLKDFSLTLRPGQTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWL 536
Query: 503 R-RLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQT 561
R +LG ++Q+P+LF +IL+NI Y P E + A + F+ PDG T
Sbjct: 537 RSNVLGFIEQQPVLFGTSILENIRYGKPDA---GEEDVYAAARLSQSHDFVTALPDGYAT 593
Query: 562 TVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKT 621
VG RGTQLSGGQ+QRIA+ARA L +P ILILDEATSALD+ SE V ++L + +T
Sbjct: 594 HVGERGTQLSGGQRQRIAIARALLKNPRILILDEATSALDATSEAEVQKAL-DTVVQNRT 652
Query: 622 TISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
T+ IAHR+STI+++ ++VL++ G V ETG D+L+
Sbjct: 653 TLVIAHRLSTIRNADLIVVLDQ-GRVVETGKHDELM 687
>At1g02520 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1278
Score = 277 bits (709), Expect = 4e-74
Identities = 171/512 (33%), Positives = 269/512 (52%), Gaps = 10/512 (1%)
Query: 152 YTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDH--NRVGDLI 209
+ ALG V + + ++ + V G +L+ R+R+ + A+ + + D N G +
Sbjct: 756 FVALG---VTSLIVSPTQMYLFAVAGGKLIRRIRSMCFEKAVHMEVAWFDEPQNSSGTMG 812
Query: 210 SRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVY 269
+RLS+DA ++ V LS + V G + SW+L +++++ P +G+ V
Sbjct: 813 ARLSADATLIRALVGDALSLAVQNVASAASGLIIAFTASWELALIILVMLPLIGINGFVQ 872
Query: 270 GKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEA 329
K ++ S ++ E ++V+ + + + +T+ ++C E+K + Y + G+K+
Sbjct: 873 VKFMKGFSADAKSKYEEASQVANDAVGSIRTVASFCAEEKVMQMYKKQCEGPIKDGIKQG 932
Query: 330 LTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXX 389
SG FG + F+ G +++ G T ++
Sbjct: 933 FISGLGFGFSFFILFCVYATSFYAGARLVEDGKTTFNNVFQVFFALTMAAIGISQSSTFA 992
Query: 390 XELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKS--IHFNHVKFSYPTRPQHHIFE 447
+ K AAA +F + DRK I + + LEN I H+ F+YP RP IF
Sbjct: 993 PDSSKAKVAAASIFAIIDRKSKIDSS-DETGTVLENVKGDIELRHLSFTYPARPDIQIFR 1051
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLG 507
DL T+R G+ V +VG SG GKSTV SLL R+YD SG I L ++ L+ R+ +G
Sbjct: 1052 DLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGHITLDGVELKKLQLKWLRQQMG 1111
Query: 508 VVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRG 567
+V QEP+LF+ TI NI Y E E+ I A AN KF+++ G T VG RG
Sbjct: 1112 LVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELANAHKFISSIQQGYDTVVGERG 1171
Query: 568 TQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAH 627
QLSGGQKQR+A+ARA + +P IL+LDEATSALD++SE VV +L R +TTI +AH
Sbjct: 1172 IQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDAL-DRVMVNRTTIVVAH 1230
Query: 628 RVSTIQHSSRVIVLNRHGTVAETGSFDKLIAI 659
R+STI+++ VI + ++G +AE G+ + LI I
Sbjct: 1231 RLSTIKNAD-VIAVVKNGVIAEKGTHETLIKI 1261
Score = 273 bits (698), Expect = 7e-73
Identities = 172/517 (33%), Positives = 272/517 (52%), Gaps = 13/517 (2%)
Query: 159 FVVGALANVG----RIVILKVTGERLVARLRTRTMKAALEQDATFLD-HNRVGDLISRLS 213
FV L +G ++ +TGER AR+R+ +K L QD F D G+++ R+S
Sbjct: 106 FVYLGLGTLGAAFLQVACWMITGERQAARIRSTYLKTILRQDIGFFDVETNTGEVVGRMS 165
Query: 214 SDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFIS-WKLTCVMMLLAPPLGVMALVYGKR 272
D ++ ++ + + + ++ FVG +++FI W LT VM+ P L +
Sbjct: 166 GDTVLIQDAMGEKVGKFIQ-LVSTFVGGFVLAFIKGWLLTLVMLTSIPLLAMAGAAMALI 224
Query: 273 IRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTS 332
+ S + Q + + V E+ + + +T+ ++ GEK+ I+ Y + + +++ ++
Sbjct: 225 VTRASSRGQAAYAKAATVVEQTIGSIRTVASFTGEKQAINSYKKFITSAYKSSIQQGFST 284
Query: 333 GAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXEL 392
G GV FV + + G MI T G + + ++ V
Sbjct: 285 GLGLGVMFFVFFSSYALAIWFGGKMILEKGYTGGAVINVIIIVVAGSMSLGQTSPCVTAF 344
Query: 393 MKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKS-IHFNHVKFSYPTRPQHHIFEDLNF 451
G AA ++FE RKPLI V + + I V FSYP RP IF+ +
Sbjct: 345 AAGQAAAYKMFETIKRKPLIDAYDVNGKVLEDIRGDIELKDVHFSYPARPDEEIFDGFSL 404
Query: 452 TVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQ 511
+ G +VG SG GKSTV SL+ R+YD SG + + N+++F L+ R +G+V Q
Sbjct: 405 FIPSGATAALVGESGSGKSTVISLIERFYDPKSGAVLIDGVNLKEFQLKWIRSKIGLVSQ 464
Query: 512 EPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLS 571
EP+LFS +I++NI Y V + I A AN KF+ P GL T VG GTQLS
Sbjct: 465 EPVLFSSSIMENIAYGKENATVEE---IKAATELANAAKFIDKLPQGLDTMVGEHGTQLS 521
Query: 572 GGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVST 631
GGQKQRIA+ARA L DP IL+LDEATSALD++SE VV ++L R +TT+ +AHR+ST
Sbjct: 522 GGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEAL-DRVMVNRTTVIVAHRLST 580
Query: 632 IQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLL 668
++++ + V++R G + E GS +L+ + + ++L+
Sbjct: 581 VRNADMIAVIHR-GKMVEKGSHSELLKDSEGAYSQLI 616
>At4g01820 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1229
Score = 275 bits (702), Expect = 2e-73
Identities = 166/492 (33%), Positives = 258/492 (51%), Gaps = 8/492 (1%)
Query: 172 ILKVTGERLVARLRTRTMKAALEQDATFLD--HNRVGDLISRLSSDAGIVSKSVTQNLSD 229
+ V G RL+ R+R + + + + D N G + SRLS+DA ++ V +LS
Sbjct: 725 LFAVAGGRLIQRIRVMCFEKVVHMEVGWFDDPENSSGTIGSRLSADAALIKTLVGDSLSL 784
Query: 230 GTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTK 289
+ G + SWKL +++++ P +G+ + K I+ + + E ++
Sbjct: 785 SVKNAAAAVSGLIIAFTASWKLAVIILVMIPLIGINGYLQIKFIKGFTADAKAKYEEASQ 844
Query: 290 VSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLA 349
V+ + + + +T+ ++C E+K + Y G+K+ L SG FG++ FV +
Sbjct: 845 VANDAVGSIRTVASFCAEEKVMEMYKKRCEDTIKSGIKQGLISGVGFGISFFVLYSVYAS 904
Query: 350 LLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRK 409
G ++K G D+ + + K GAAA +F + D K
Sbjct: 905 CFYVGARLVKAGRTNFNDVFQVFLALTMTAIGISQASSFAPDSSKAKGAAASIFGIIDGK 964
Query: 410 PLIHPTIGKDPVTLENKS--IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGG 467
+I + + LEN I H+ F+Y TRP IF DL F +R G+ V +VG SG
Sbjct: 965 SMIDSR-DESGLVLENVKGDIELCHISFTYQTRPDVQIFRDLCFAIRAGQTVALVGESGS 1023
Query: 468 GKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYA 527
GKSTV SLL R+YD SG I L ++ L+ R+ +G+V QEP+LF+ TI NI Y
Sbjct: 1024 GKSTVISLLQRFYDPDSGHITLDRVELKKLQLKWVRQQMGLVGQEPVLFNDTIRSNIAYG 1083
Query: 528 VPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLD 587
+ + E I A AN F+++ G T VG RG QLSGGQKQR+A+ARA + +
Sbjct: 1084 KGGDEAS-EAEIIAAAELANAHGFISSIQQGYDTVVGERGIQLSGGQKQRVAIARAIVKE 1142
Query: 588 PSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTV 647
P IL+LDEATSALD++SE VV +L R +TT+ +AHR+STI+++ VI + ++G +
Sbjct: 1143 PKILLLDEATSALDAESERVVQDAL-DRVMVNRTTVVVAHRLSTIKNAD-VIAVVKNGVI 1200
Query: 648 AETGSFDKLIAI 659
E G+ + LI I
Sbjct: 1201 VEKGTHETLINI 1212
Score = 271 bits (693), Expect = 3e-72
Identities = 172/523 (32%), Positives = 273/523 (51%), Gaps = 25/523 (4%)
Query: 159 FVVGALANVG----RIVILKVTGERLVARLRTRTMKAALEQDATFLD-HNRVGDLISRLS 213
FV L +G ++ +TGER AR+R+ +K L QD F D G+++ R+S
Sbjct: 73 FVYLGLGTLGAAFLQVACWMITGERQAARIRSLYLKTILRQDIGFFDVETSTGEVVGRMS 132
Query: 214 SDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFIS-WKLTCVMMLLAPPLGVMALVYGKR 272
D ++ +++ + + + +I FVG +++F+ W LT VM++ P L +
Sbjct: 133 GDTVLILEAMGEKVGKFIQ-LIATFVGGFVLAFVKGWLLTLVMLVSIPLLAIAGAAMPII 191
Query: 273 IRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTS 332
+ S + Q + + + V E+ L + +T+ ++ GEK+ + Y + + + +K+ +
Sbjct: 192 VTRASSREQAAYAKASTVVEQTLGSIRTVASFTGEKQAMKSYREFINLAYRASVKQGFSM 251
Query: 333 GAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXEL 392
G GV FV + + G MI T G++ + M+ V
Sbjct: 252 GLGLGVVFFVFFCSYALAIWFGGEMILKKGYTGGEVVNVMVTVVASSMSLGQTTPCLTAF 311
Query: 393 MKGAGAAARVFELNDRKPLIHPTIGKDPVTLENK-------SIHFNHVKFSYPTRPQHHI 445
G AA ++FE +RKP I D L K I V FSYP RP +
Sbjct: 312 AAGKAAAYKMFETIERKPSI------DAFDLNGKVLEDIRGEIELRDVCFSYPARPMEEV 365
Query: 446 FEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRL 505
F + + G +VG SG GKS+V SL+ R+YD SG + + N+++F L+ R
Sbjct: 366 FGGFSLLIPSGATAALVGESGSGKSSVISLIERFYDPSSGSVLIDGVNLKEFQLKWIRGK 425
Query: 506 LGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGP 565
+G+V QEP+LFS +I++NI Y V + I A AN F+ P GL+T VG
Sbjct: 426 IGLVSQEPVLFSSSIMENIGYGKENATVEE---IQAAAKLANAANFIDKLPRGLETLVGE 482
Query: 566 RGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISI 625
GTQLSGGQKQRIA+ARA L DP IL+LDEATSALD++SE VV ++L R +TT+ +
Sbjct: 483 HGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEAL-DRVMMSRTTVIV 541
Query: 626 AHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLL 668
AHR+ST++++ + V++R G + E GS +L+ + + +L+
Sbjct: 542 AHRLSTVRNADMIAVIHR-GKIVEEGSHSELLKDHEGAYAQLI 583
>Hs4505769 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1279
Score = 274 bits (700), Expect = 4e-73
Identities = 170/510 (33%), Positives = 285/510 (55%), Gaps = 14/510 (2%)
Query: 151 FYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLIS 210
+Y+ +G +V A V + R + ++R + A + Q+ + D + VG+L +
Sbjct: 117 YYSGIGAGVLVAAYIQVS---FWCLAAGRQIHKIRKQFFHAIMRQEIGWFDVHDVGELNT 173
Query: 211 RLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYG 270
RL+ D +++ + + +++ F GF + WKLT V++ ++P LG+ A V+
Sbjct: 174 RLTDDVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGWKLTLVILAISPVLGLSAAVWA 233
Query: 271 KRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEAL 330
K + + + + + + V+EE L+A +T+ A+ G+KKE+ RY + + +G+K+A+
Sbjct: 234 KILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAI 293
Query: 331 TSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXX 390
T+ G + + GT+++ +G ++G + + +++V
Sbjct: 294 TANISIGAAFLLIYASYALAFWYGTTLVLSGEYSIGQVLT--VFSVLIGAFSVGQASPSI 351
Query: 391 ELMKGA-GAAARVFELNDRKPLI--HPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFE 447
E A GAA +F++ D KP I + G P ++ ++ F +V FSYP+R + I +
Sbjct: 352 EAFANARGAAYEIFKIIDNKPSIDSYSKSGHKPDNIKG-NLEFRNVHFSYPSRKEVKILK 410
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLG 507
LN V+ G+ V +VG SG GKST L+ R YD G + + +IR N+R R ++G
Sbjct: 411 GLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIG 470
Query: 508 VVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRG 567
VV QEP+LF+ TI +NI Y + + DE I +A+ +AN F+ P T VG RG
Sbjct: 471 VVSQEPVLFATTIAENIRYG-RENVTMDE--IEKAVKEANAYDFIMKLPHKFDTLVGERG 527
Query: 568 TQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAH 627
QLSGGQKQRIA+ARA + +P IL+LDEATSALD++SE VV +L ++ +G+TTI IAH
Sbjct: 528 AQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVAL-DKARKGRTTIVIAH 586
Query: 628 RVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
R+ST++++ VI G + E G+ D+L+
Sbjct: 587 RLSTVRNAD-VIAGFDDGVIVEKGNHDELM 615
Score = 251 bits (640), Expect = 4e-66
Identities = 162/486 (33%), Positives = 262/486 (53%), Gaps = 8/486 (1%)
Query: 177 GERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSSDAGIVSKSVTQNLSDGTRAV 234
GE L RLR ++ L QD ++ D N G L +RL++DA V ++ L+ T+ +
Sbjct: 780 GEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQNI 839
Query: 235 IQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQ 294
G + W+LT +++ + P + + +V K + + + + + K++ E
Sbjct: 840 ANLGTGIIISFIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGAGKIATEA 899
Query: 295 LSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTG 354
+ +T+ + E+K H YA ++ + L++A G F T + + G
Sbjct: 900 IENFRTVVSLTQEQKFEHMYAQSLQVPYRNSLRKAHIFGITFSFTQAMMYFSYAGCFRFG 959
Query: 355 TSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLI-- 412
++ LM+ D+ V + K +AA + + ++ PLI
Sbjct: 960 AYLVAHKLMSFEDVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISAAHIIMIIEKTPLIDS 1019
Query: 413 HPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTV 472
+ T G P TLE ++ F V F+YPTRP + + L+ V+ G+ + +VG SG GKSTV
Sbjct: 1020 YSTEGLMPNTLEG-NVTFGEVVFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTV 1078
Query: 473 ASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQEL 532
LL R+YD +G++ L I+ N++ R LG+V QEP+LF +I +NI Y +
Sbjct: 1079 VQLLERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRV 1138
Query: 533 VNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILI 592
V+ E I RA +AN F+ + P+ T VG +GTQLSGGQKQRIA+ARA + P IL+
Sbjct: 1139 VSQE-EIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILL 1197
Query: 593 LDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGS 652
LDEATSALD++SE+VV ++L ++ G+T I IAHR+STIQ++ ++V ++G V E G+
Sbjct: 1198 LDEATSALDTESEKVVQEAL-DKAREGRTCIVIAHRLSTIQNADLIVVF-QNGRVKEHGT 1255
Query: 653 FDKLIA 658
+L+A
Sbjct: 1256 HQQLLA 1261
>At3g62150 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1292
Score = 273 bits (699), Expect = 5e-73
Identities = 173/520 (33%), Positives = 271/520 (51%), Gaps = 12/520 (2%)
Query: 152 YTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLD-HNRVGDLIS 210
+ LG +V AL V +I +GER R+R+ ++ L QD F D G+++
Sbjct: 128 FVYLGLGTLVAALLQVSGWMI---SGERQAGRIRSLYLQTILRQDIAFFDVETNTGEVVG 184
Query: 211 RLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYG 270
R+S D ++ ++ + + + V GF + W LT VM+ P L +
Sbjct: 185 RMSGDTVLIQDAMGEKVGKAIQLVSTFIGGFVIAFTEGWLLTLVMVSSIPLLVMSGAALA 244
Query: 271 KRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEAL 330
I ++ + QTS + V E+ + + +T+ ++ GEK+ I Y + + G+ E
Sbjct: 245 IVISKMASRGQTSYAKAAVVVEQTVGSIRTVASFTGEKQAISNYNKHLVSAYRAGVFEGA 304
Query: 331 TSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXX 390
++G G V + G MI T G + + +
Sbjct: 305 STGLGLGTLNIVIFCTYALAVWYGGKMILEKGYTGGQVLIIIFAVLTGSMSLGQASPCLS 364
Query: 391 ELMKGAGAAARVFELNDRKPLIHP--TIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFED 448
G AA ++FE RKP I T GK + I N+V FSYP RP+ IF
Sbjct: 365 AFAAGQAAAYKMFEAIKRKPEIDASDTTGKVLDDIRG-DIELNNVNFSYPARPEEQIFRG 423
Query: 449 LNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGV 508
+ ++ G V +VG SG GKSTV SL+ R+YD SGE+++ N+++F L+ R +G+
Sbjct: 424 FSLSISSGSTVALVGQSGSGKSTVVSLIERFYDPQSGEVRIDGINLKEFQLKWIRSKIGL 483
Query: 509 VQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGT 568
V QEP+LF+ +I +NI Y V + I +A AN +KF+ P GL T VG GT
Sbjct: 484 VSQEPVLFTSSIKENIAYGKENATVEE---IRKATELANASKFIDKLPQGLDTMVGEHGT 540
Query: 569 QLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHR 628
QLSGGQKQRIA+ARA L DP IL+LDEATSALD++SE +V ++L R +TT+ +AHR
Sbjct: 541 QLSGGQKQRIAVARAILKDPRILLLDEATSALDAESERIVQEAL-DRIMVNRTTVVVAHR 599
Query: 629 VSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLL 668
+ST++++ + V+++ G + E GS +L+ P+ + ++L+
Sbjct: 600 LSTVRNADMIAVIHQ-GKIVEKGSHSELLRDPEGAYSQLI 638
Score = 261 bits (666), Expect = 3e-69
Identities = 161/494 (32%), Positives = 256/494 (51%), Gaps = 11/494 (2%)
Query: 171 VILKVTGERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSSDAGIVSKSVTQNLS 228
+ + G +LV R+R+ + + + + D N G + +RLS+DA V V L+
Sbjct: 792 IFFSIAGCKLVQRIRSMCFEKVVRMEVGWFDETENSSGAIGARLSADAATVRGLVGDALA 851
Query: 229 DGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELT 288
+ + G + SW+L +++ + P +G+ +Y K + S + E +
Sbjct: 852 QTVQNLASVTAGLVIAFVASWQLAFIVLAMLPLIGLNGYIYMKFMVGFSADAK----EAS 907
Query: 289 KVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALL 348
+V+ + + + +T+ ++C E+K + Y + G+++ + SG FGV+ FV +
Sbjct: 908 QVANDAVGSIRTVASFCAEEKVMKMYKKKCEGPMRTGIRQGIVSGIGFGVSFFVLFSSYA 967
Query: 349 ALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDR 408
A G ++ G T + + K + AAA +F + DR
Sbjct: 968 ASFYAGARLVDDGKTTFDSVFRVFFALTMAAVAISQSSSLSPDSSKASNAAASIFAVIDR 1027
Query: 409 KPLIHPTIGKDPVTLENKS-IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGG 467
+ I P+ V K I H+ F YP+RP IF+DL ++R G+ + +VG SG
Sbjct: 1028 ESKIDPSDESGRVLDNVKGDIELRHISFKYPSRPDVQIFQDLCLSIRAGKTIALVGESGS 1087
Query: 468 GKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYA 527
GKSTV +LL R+YD SG+I L I+ L+ R+ G+V QEP+LF+ TI NI Y
Sbjct: 1088 GKSTVIALLQRFYDPDSGQITLDGVEIKTLQLKWLRQQTGLVSQEPVLFNETIRANIAYG 1147
Query: 528 VPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLD 587
+ ET I A +N F++ G T VG RG QLSGGQKQR+A+ARA + D
Sbjct: 1148 KGGDAT--ETEIVSAAELSNAHGFISGLQQGYDTMVGERGVQLSGGQKQRVAIARAIVKD 1205
Query: 588 PSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTV 647
P +L+LDEATSALD++SE VV +L R +TT+ +AHR+STI+++ VI + ++G +
Sbjct: 1206 PKVLLLDEATSALDAESERVVQDAL-DRVMVNRTTVVVAHRLSTIKNAD-VIAVVKNGVI 1263
Query: 648 AETGSFDKLIAIPD 661
E G + LI I D
Sbjct: 1264 VEKGKHETLINIKD 1277
>Hs9961252 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1232
Score = 272 bits (695), Expect = 1e-72
Identities = 169/509 (33%), Positives = 270/509 (52%), Gaps = 11/509 (2%)
Query: 151 FYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLIS 210
+Y+ LG +V A V + R + ++R + A L Q+ + D N +L +
Sbjct: 119 YYSGLGAGVLVAAYIQVS---FWTLAAGRQIRKIRQKFFHAILRQEIGWFDINDTTELNT 175
Query: 211 RLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYG 270
RL+ D +S+ + + +AV F GF + WKLT V+M ++P LG+ A V+
Sbjct: 176 RLTDDISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWA 235
Query: 271 KRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEAL 330
K + S + + + V+EE L A +T+ A+ G+ KE+ RY + +G+K+A+
Sbjct: 236 KILSAFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKEIGIKKAI 295
Query: 331 TSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXX 390
++ G+ + + G++++ + T+G+ + +
Sbjct: 296 SANISMGIAFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILIGAFSVGQAAPCID 355
Query: 391 ELMKGAGAAARVFELNDRKPLIHPTI--GKDPVTLENKSIHFNHVKFSYPTRPQHHIFED 448
GAA +F++ D P I G P +++ ++ FN V FSYP+R I +
Sbjct: 356 AFANARGAAYVIFDIIDNNPKIDSFSERGHKPDSIKG-NLEFNDVHFSYPSRANVKILKG 414
Query: 449 LNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGV 508
LN V+ G+ V +VG SG GKST L+ R YD G I + +IR+FN+ R ++GV
Sbjct: 415 LNLKVQSGQTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGV 474
Query: 509 VQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGT 568
V QEP+LFS TI +NI Y +++ I +A+ +AN +F+ P T VG RG
Sbjct: 475 VSQEPVLFSTTIAENICYGRGNVTMDE---IKKAVKEANAYEFIMKLPQKFDTLVGERGA 531
Query: 569 QLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHR 628
QLSGGQKQRIA+ARA + +P IL+LDEATSALD++SE V Q+ ++ G+TTI IAHR
Sbjct: 532 QLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEV-QAALDKAREGRTTIVIAHR 590
Query: 629 VSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ST++++ VI G + E GS +L+
Sbjct: 591 LSTVRNAD-VIAGFEDGVIVEQGSHSELM 618
Score = 224 bits (570), Expect = 5e-58
Identities = 162/490 (33%), Positives = 252/490 (51%), Gaps = 63/490 (12%)
Query: 177 GERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSSDAGIVSKSVTQNLSDGTRAV 234
GE L RLR+ KA L QD ++ D N G L +RL++DA V + L+ +
Sbjct: 780 GEILTRRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLA----LI 835
Query: 235 IQGFVGFG---MMSFI-SWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKV 290
Q G ++SFI W+LT +++ + P + V +V K + +++ + + K+
Sbjct: 836 AQNIANLGTGIIISFIYGWQLTLLLLAVVPIIAVSGIVEMKLLAGNAKRDKKELEAAGKI 895
Query: 291 SEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLAL 350
+ E + +T+ + E+K Y +++ + V
Sbjct: 896 ATEAIENIRTVVSLTQERKFESMYVEKLYGPYRV-------------------------- 929
Query: 351 LLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKP 410
S I G + +G SSF + K +AA +F L +R+P
Sbjct: 930 ----FSAIVFGAVALGHASSF-----------------APDYAKAKLSAAHLFMLFERQP 968
Query: 411 LI--HPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGG 468
LI + G P E +I FN V F+YPTR + + L+ V+ G+ + +VG SG G
Sbjct: 969 LIDSYSEEGLKPDKFEG-NITFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCG 1027
Query: 469 KSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAV 528
KSTV LL R+YD +G + L + N++ R LG+V QEP+LF +I +NI Y
Sbjct: 1028 KSTVVQLLERFYDPLAGTVLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGD 1087
Query: 529 PQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDP 588
+V+ + +S A AN F+ P +T VG +GTQLSGGQKQRIA+ARA + P
Sbjct: 1088 NSRVVSQDEIVS-AAKAANIHPFIETLPHKYETRVGDKGTQLSGGQKQRIAIARALIRQP 1146
Query: 589 SILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVA 648
IL+LDEATSALD++SE+VV ++L ++ G+T I IAHR+STIQ++ ++V ++G V
Sbjct: 1147 QILLLDEATSALDTESEKVVQEAL-DKAREGRTCIVIAHRLSTIQNADLIVVF-QNGRVK 1204
Query: 649 ETGSFDKLIA 658
E G+ +L+A
Sbjct: 1205 EHGTHQQLLA 1214
>Hs9961250 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1286
Score = 272 bits (695), Expect = 1e-72
Identities = 169/509 (33%), Positives = 270/509 (52%), Gaps = 11/509 (2%)
Query: 151 FYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLIS 210
+Y+ LG +V A V + R + ++R + A L Q+ + D N +L +
Sbjct: 119 YYSGLGAGVLVAAYIQVS---FWTLAAGRQIRKIRQKFFHAILRQEIGWFDINDTTELNT 175
Query: 211 RLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYG 270
RL+ D +S+ + + +AV F GF + WKLT V+M ++P LG+ A V+
Sbjct: 176 RLTDDISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWA 235
Query: 271 KRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEAL 330
K + S + + + V+EE L A +T+ A+ G+ KE+ RY + +G+K+A+
Sbjct: 236 KILSAFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKEIGIKKAI 295
Query: 331 TSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXX 390
++ G+ + + G++++ + T+G+ + +
Sbjct: 296 SANISMGIAFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILIGAFSVGQAAPCID 355
Query: 391 ELMKGAGAAARVFELNDRKPLIHPTI--GKDPVTLENKSIHFNHVKFSYPTRPQHHIFED 448
GAA +F++ D P I G P +++ ++ FN V FSYP+R I +
Sbjct: 356 AFANARGAAYVIFDIIDNNPKIDSFSERGHKPDSIKG-NLEFNDVHFSYPSRANVKILKG 414
Query: 449 LNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGV 508
LN V+ G+ V +VG SG GKST L+ R YD G I + +IR+FN+ R ++GV
Sbjct: 415 LNLKVQSGQTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGV 474
Query: 509 VQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGT 568
V QEP+LFS TI +NI Y +++ I +A+ +AN +F+ P T VG RG
Sbjct: 475 VSQEPVLFSTTIAENICYGRGNVTMDE---IKKAVKEANAYEFIMKLPQKFDTLVGERGA 531
Query: 569 QLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHR 628
QLSGGQKQRIA+ARA + +P IL+LDEATSALD++SE V Q+ ++ G+TTI IAHR
Sbjct: 532 QLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEV-QAALDKAREGRTTIVIAHR 590
Query: 629 VSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ST++++ VI G + E GS +L+
Sbjct: 591 LSTVRNAD-VIAGFEDGVIVEQGSHSELM 618
Score = 232 bits (592), Expect = 1e-60
Identities = 163/497 (32%), Positives = 259/497 (51%), Gaps = 23/497 (4%)
Query: 177 GERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSSDAGIVSKSVTQNLSDGTRAV 234
GE L RLR+ KA L QD ++ D N G L +RL++DA V + L+ +
Sbjct: 780 GEILTRRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLA----LI 835
Query: 235 IQGFVGFG---MMSFI-SWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKV 290
Q G ++SFI W+LT +++ + P + V +V K + +++ + + K+
Sbjct: 836 AQNIANLGTGIIISFIYGWQLTLLLLAVVPIIAVSGIVEMKLLAGNAKRDKKELEAAGKI 895
Query: 291 SEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLAL 350
+ E + +T+ + E+K Y +++ + +++A G F ++ +
Sbjct: 896 ATEAIENIRTVVSLTQERKFESMYVEKLYGPYRNSVQKAHIYGITFSISQAFMYFSYAGC 955
Query: 351 LLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKP 410
G +I G M D+ V + K +AA +F L +R+P
Sbjct: 956 FRFGAYLIVNGHMRFRDVILVFSAIVFGAVALGHASSFAPDYAKAKLSAAHLFMLFERQP 1015
Query: 411 LI--HPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGG 468
LI + G P E +I FN V F+YPTR + + L+ V+ G+ + +VG SG G
Sbjct: 1016 LIDSYSEEGLKPDKFEG-NITFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCG 1074
Query: 469 KSTVASLLLRYYDIGSGEI-------KLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTIL 521
KSTV LL R+YD +G + L + N++ R LG+V QEP+LF +I
Sbjct: 1075 KSTVVQLLERFYDPLAGTVFVDFGFQLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIA 1134
Query: 522 DNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALA 581
+NI Y +V+ + +S A AN F+ P +T VG +GTQLSGGQKQRIA+A
Sbjct: 1135 ENIAYGDNSRVVSQDEIVSAAKA-ANIHPFIETLPHKYETRVGDKGTQLSGGQKQRIAIA 1193
Query: 582 RAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVL 641
RA + P IL+LDEATSALD++SE+VV ++L ++ G+T I IAHR+STIQ++ ++V
Sbjct: 1194 RALIRQPQILLLDEATSALDTESEKVVQEAL-DKAREGRTCIVIAHRLSTIQNADLIVVF 1252
Query: 642 NRHGTVAETGSFDKLIA 658
++G V E G+ +L+A
Sbjct: 1253 -QNGRVKEHGTHQQLLA 1268
>Hs4505771 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1279
Score = 272 bits (695), Expect = 1e-72
Identities = 169/509 (33%), Positives = 270/509 (52%), Gaps = 11/509 (2%)
Query: 151 FYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLIS 210
+Y+ LG +V A V + R + ++R + A L Q+ + D N +L +
Sbjct: 119 YYSGLGAGVLVAAYIQVS---FWTLAAGRQIRKIRQKFFHAILRQEIGWFDINDTTELNT 175
Query: 211 RLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYG 270
RL+ D +S+ + + +AV F GF + WKLT V+M ++P LG+ A V+
Sbjct: 176 RLTDDISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWA 235
Query: 271 KRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEAL 330
K + S + + + V+EE L A +T+ A+ G+ KE+ RY + +G+K+A+
Sbjct: 236 KILSAFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKEIGIKKAI 295
Query: 331 TSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXX 390
++ G+ + + G++++ + T+G+ + +
Sbjct: 296 SANISMGIAFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILIGAFSVGQAAPCID 355
Query: 391 ELMKGAGAAARVFELNDRKPLIHPTI--GKDPVTLENKSIHFNHVKFSYPTRPQHHIFED 448
GAA +F++ D P I G P +++ ++ FN V FSYP+R I +
Sbjct: 356 AFANARGAAYVIFDIIDNNPKIDSFSERGHKPDSIKG-NLEFNDVHFSYPSRANVKILKG 414
Query: 449 LNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGV 508
LN V+ G+ V +VG SG GKST L+ R YD G I + +IR+FN+ R ++GV
Sbjct: 415 LNLKVQSGQTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGV 474
Query: 509 VQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGT 568
V QEP+LFS TI +NI Y +++ I +A+ +AN +F+ P T VG RG
Sbjct: 475 VSQEPVLFSTTIAENICYGRGNVTMDE---IKKAVKEANAYEFIMKLPQKFDTLVGERGA 531
Query: 569 QLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHR 628
QLSGGQKQRIA+ARA + +P IL+LDEATSALD++SE V Q+ ++ G+TTI IAHR
Sbjct: 532 QLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEV-QAALDKAREGRTTIVIAHR 590
Query: 629 VSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ST++++ VI G + E GS +L+
Sbjct: 591 LSTVRNAD-VIAGFEDGVIVEQGSHSELM 618
Score = 239 bits (610), Expect = 1e-62
Identities = 163/490 (33%), Positives = 259/490 (52%), Gaps = 16/490 (3%)
Query: 177 GERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSSDAGIVSKSVTQNLSDGTRAV 234
GE L RLR+ KA L QD ++ D N G L +RL++DA V + L+ +
Sbjct: 780 GEILTRRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLA----LI 835
Query: 235 IQGFVGFG---MMSFI-SWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKV 290
Q G ++SFI W+LT +++ + P + V +V K + +++ + + K+
Sbjct: 836 AQNIANLGTGIIISFIYGWQLTLLLLAVVPIIAVSGIVEMKLLAGNAKRDKKELEAAGKI 895
Query: 291 SEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLAL 350
+ E + +T+ + E+K Y +++ + +++A G F ++ +
Sbjct: 896 ATEAIENIRTVVSLTQERKFESMYVEKLYGPYRNSVQKAHIYGITFSISQAFMYFSYAGC 955
Query: 351 LLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKP 410
G +I G M D+ V + K +AA +F L +R+P
Sbjct: 956 FRFGAYLIVNGHMRFRDVILVFSAIVFGAVALGHASSFAPDYAKAKLSAAHLFMLFERQP 1015
Query: 411 LI--HPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGG 468
LI + G P E +I FN V F+YPTR + + L+ V+ G+ + +VG SG G
Sbjct: 1016 LIDSYSEEGLKPDKFEG-NITFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCG 1074
Query: 469 KSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAV 528
KSTV LL R+YD +G + L + N++ R LG+V QEP+LF +I +NI Y
Sbjct: 1075 KSTVVQLLERFYDPLAGTVLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGD 1134
Query: 529 PQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDP 588
+V+ + +S A AN F+ P +T VG +GTQLSGGQKQRIA+ARA + P
Sbjct: 1135 NSRVVSQDEIVS-AAKAANIHPFIETLPHKYETRVGDKGTQLSGGQKQRIAIARALIRQP 1193
Query: 589 SILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVA 648
IL+LDEATSALD++SE+VV ++L ++ G+T I IAHR+STIQ++ ++V ++G V
Sbjct: 1194 QILLLDEATSALDTESEKVVQEAL-DKAREGRTCIVIAHRLSTIQNADLIVVF-QNGRVK 1251
Query: 649 ETGSFDKLIA 658
E G+ +L+A
Sbjct: 1252 EHGTHQQLLA 1261
>At1g28010 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1247
Score = 271 bits (694), Expect = 2e-72
Identities = 174/487 (35%), Positives = 273/487 (55%), Gaps = 11/487 (2%)
Query: 176 TGERLVARLRTRTMKAALEQDATFLDHN-RVGDLISRLSSDAGIVSKSVTQNLSDGTRAV 234
TGER ARLR +K+ L +D TF D R + I +SSDA +V ++ R +
Sbjct: 118 TGERQTARLRINYLKSILAKDITFFDTEARDSNFIFHISSDAILVQDAIGDKTGHVLRYL 177
Query: 235 IQGFVGFGMMSFIS-WKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEE 293
Q GF ++ F+S W+LT + + + P + + Y + +S + + + + KV+EE
Sbjct: 178 CQFIAGF-VIGFLSVWQLTLLTLGVVPLIAIAGGGYAIVMSTISEKSEAAYADAGKVAEE 236
Query: 294 QLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLT 353
+S +T+ A+ GE+K + Y++ ++K + + L G G+T + A L
Sbjct: 237 VMSQVRTVYAFVGEEKAVKSYSNSLKKALKLSKRSGLAKGLGVGLTYSLLFCAWALLFWY 296
Query: 354 GTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIH 413
+ +++ G + ++ + + KG AAA +F++ L
Sbjct: 297 ASLLVRHGKTNGAKAFTTILNVIYSGFALGQAVPSLSAISKGRVAAANIFKMIGNNNLES 356
Query: 414 PTIGKDPVTLENK--SIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKST 471
++ TL+N I F V F+YP+RP + +FE+L+FT+ G+ VGPSG GKST
Sbjct: 357 SERLENGTTLQNVVGKIEFCGVSFAYPSRP-NMVFENLSFTIHSGKTFAFVGPSGSGKST 415
Query: 472 VASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQE 531
+ S++ R+Y+ SGEI L ++I++ L+ R +G+V QEP LF+ TI NI +E
Sbjct: 416 IISMVQRFYEPRSGEILLDGNDIKNLKLKWLREQMGLVSQEPALFATTIASNILLG--KE 473
Query: 532 LVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSIL 591
N + +I A AN F+ + P+G T VG GTQLSGGQKQRIA+ARA L +P IL
Sbjct: 474 KANMD-QIIEAAKAANADSFIKSLPNGYNTQVGEGGTQLSGGQKQRIAIARAVLRNPKIL 532
Query: 592 ILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETG 651
+LDEATSALD++SE++V Q+L + +TTI IAHR+STI++ +++VL R G V ETG
Sbjct: 533 LLDEATSALDAESEKIVQQALDNVMEK-RTTIVIAHRLSTIRNVDKIVVL-RDGQVRETG 590
Query: 652 SFDKLIA 658
S +LI+
Sbjct: 591 SHSELIS 597
Score = 260 bits (664), Expect = 6e-69
Identities = 171/520 (32%), Positives = 265/520 (50%), Gaps = 13/520 (2%)
Query: 158 VFVVGALANVGRIVILK-----VTGERLVARLRTRTMKAALEQDATF--LDHNRVGDLIS 210
+ VGA I IL+ + GERL +R+R A L + + LD N G L S
Sbjct: 728 IIFVGAGIVTAPIYILQHYFYTLMGERLTSRVRLSLFSAILSNEIGWFDLDENNTGSLTS 787
Query: 211 RLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYG 270
L++DA +V ++ LS + + + F SW++ V+ P L +L
Sbjct: 788 ILAADATLVRSAIADRLSTIVQNLSLTITALALAFFYSWRVAAVVTACFPLLIAASLTEQ 847
Query: 271 KRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEAL 330
++ + T ++ E +S +T+ A+ EK+ ++ E+ K L
Sbjct: 848 LFLKGFGGDYTRAYSRATSLAREAISNIRTVAAFSAEKQISEQFTCELSKPTKSALLRGH 907
Query: 331 TSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXX 390
SG +G++ + + L + +IK D M +
Sbjct: 908 ISGFGYGLSQCLAFCSYALGLWYISVLIKRNETNFEDSIKSFMVLLVTAYSVAETLALTP 967
Query: 391 ELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKS-IHFNHVKFSYPTRPQHHIFEDL 449
+++KG A VF + R+ I P + K I F +V F+YPTRP+ IF++L
Sbjct: 968 DIVKGTQALGSVFRVLHRETEIPPDQPNSRLVTHIKGDIEFRNVSFAYPTRPEIAIFKNL 1027
Query: 450 NFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVV 509
N V G+ + +VGPSG GKSTV L++R+YD +G + + +I+ NLR R+ L +V
Sbjct: 1028 NLRVSAGKSLAVVGPSGSGKSTVIGLIMRFYDPSNGNLCIDGHDIKSVNLRSLRKKLALV 1087
Query: 510 QQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQ 569
QQEP LFS +I +NI Y E I A AN +F++ +G T VG +G Q
Sbjct: 1088 QQEPALFSTSIHENIKYGNENA---SEAEIIEAAKAANAHEFISRMEEGYMTHVGDKGVQ 1144
Query: 570 LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRV 629
LSGGQKQR+A+ARA L DPS+L+LDEATSALD+ +E+ V ++L + +G+TTI +AHR+
Sbjct: 1145 LSGGQKQRVAIARAVLKDPSVLLLDEATSALDTSAEKQVQEAL-DKLMKGRTTILVAHRL 1203
Query: 630 STIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLS 669
STI+ + ++VL++ G V E GS +L++ D KL S
Sbjct: 1204 STIRKADTIVVLHK-GKVVEKGSHRELVSKSDGFYKKLTS 1242
>At1g02530 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1273
Score = 270 bits (691), Expect = 4e-72
Identities = 165/512 (32%), Positives = 269/512 (52%), Gaps = 10/512 (1%)
Query: 152 YTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDH--NRVGDLI 209
+ ALG V + + ++ + V G +L+ R+++ + A+ + ++ D N G +
Sbjct: 751 FVALG---VTSLIVSPSQMYLFAVAGGKLIRRIQSMCFEKAVHMEVSWFDEPENSSGTMG 807
Query: 210 SRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVY 269
+RLS+DA ++ V LS + G + SW+L +++++ P +G+ +
Sbjct: 808 ARLSTDAALIRALVGDALSLAVQNAASAASGLIIAFTASWELALIILVMLPLIGINGFLQ 867
Query: 270 GKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEA 329
K ++ S ++ E ++V+ + + + +T+ ++C E+K + Y + G+K+
Sbjct: 868 VKFMKGFSADAKSKYEEASQVANDAVGSIRTVASFCAEEKVMQMYNKQCEGPIKDGVKQG 927
Query: 330 LTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXX 389
SG FG + F+ +++ G T D+
Sbjct: 928 FISGLGFGFSFFILFCVYATSFYAAARLVEDGKTTFIDVFQVFFALTMAAIGISQSSTFA 987
Query: 390 XELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKS--IHFNHVKFSYPTRPQHHIFE 447
+ K AAA +F + DRK I + + LEN I H+ F+YP RP IF
Sbjct: 988 PDSSKAKVAAASIFAIIDRKSKIDSS-DETGTVLENVKGDIELRHLSFTYPARPGIQIFR 1046
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLG 507
DL T+R G+ V +VG SG GKSTV SLL R+YD SG+I L ++ L+ R+ +G
Sbjct: 1047 DLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGQITLDGVELKKLQLKWLRQQMG 1106
Query: 508 VVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRG 567
+V QEP+LF+ TI NI Y E E+ I A AN KF+++ G T VG +G
Sbjct: 1107 LVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELANAHKFISSIQQGYDTVVGEKG 1166
Query: 568 TQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAH 627
QLSGGQKQR+A+ARA + +P IL+LDEATSALD++SE +V +L R +TT+ +AH
Sbjct: 1167 IQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERLVQDAL-DRVIVNRTTVVVAH 1225
Query: 628 RVSTIQHSSRVIVLNRHGTVAETGSFDKLIAI 659
R+STI+++ VI + ++G +AE G+ + LI I
Sbjct: 1226 RLSTIKNAD-VIAIVKNGVIAENGTHETLIKI 1256
Score = 263 bits (673), Expect = 5e-70
Identities = 165/510 (32%), Positives = 262/510 (51%), Gaps = 21/510 (4%)
Query: 159 FVVGALANVG----RIVILKVTGERLVARLRTRTMKAALEQDATFLD-HNRVGDLISRLS 213
FV L +G ++ +TGER A++R+ +K L QD F D G+++ R+S
Sbjct: 93 FVYLGLGRLGAAFLQVACWMITGERQAAKIRSNYLKTILRQDIGFFDVETNTGEVVGRMS 152
Query: 214 SDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRI 273
D + ++ + + + V GF + W LT VM+ P L + +
Sbjct: 153 GDTVHIQDAMGEKVGKFIQLVSTFVGGFALAFAKGWLLTLVMLTSIPFLAMAGAAMALLV 212
Query: 274 RNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSG 333
S + Q + + V E+ + + +T+ ++ GEK+ I+ Y + + +++ ++G
Sbjct: 213 TRASSRGQAAYAKAATVVEQTIGSIRTVASFTGEKQAINSYKKYITSAYKSSIQQGFSTG 272
Query: 334 AFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELM 393
GV +V + + G MI T G + + ++ V
Sbjct: 273 LGLGVMIYVFFSSYALAIWFGGKMILEKGYTGGSVINVIIIVVAGSMSLGQTSPCVTAFA 332
Query: 394 KGAGAAARVFELNDRKPLIHP------TIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFE 447
G AA ++FE RKPLI +G +E K +HF SYP RP IF+
Sbjct: 333 AGQAAAYKMFETIKRKPLIDAYDVNGKVLGDIRGDIELKDVHF-----SYPARPDEEIFD 387
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLG 507
+ + G +VG SG GKSTV +L+ R+YD +GE+ + N+++F L+ R +G
Sbjct: 388 GFSLFIPSGATAALVGESGSGKSTVINLIERFYDPKAGEVLIDGINLKEFQLKWIRSKIG 447
Query: 508 VVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRG 567
+V QEP+LFS +I++NI Y + + I A AN KF+ N P GL T VG G
Sbjct: 448 LVCQEPVLFSSSIMENIAYGKENATLQE---IKVATELANAAKFINNLPQGLDTKVGEHG 504
Query: 568 TQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAH 627
TQLSGGQKQRIA+ARA L DP +L+LDEATSALD++SE VV ++L R +TT+ +AH
Sbjct: 505 TQLSGGQKQRIAIARAILKDPRVLLLDEATSALDTESERVVQEAL-DRVMVNRTTVVVAH 563
Query: 628 RVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
R+ST++++ + V++ G + E GS +L+
Sbjct: 564 RLSTVRNADMIAVIH-SGKMVEKGSHSELL 592
>At4g01830 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1230
Score = 270 bits (689), Expect = 7e-72
Identities = 163/492 (33%), Positives = 259/492 (52%), Gaps = 8/492 (1%)
Query: 172 ILKVTGERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSSDAGIVSKSVTQNLSD 229
+ + G RL+ R+R+ + + + + D N G + +RLS+DA ++ V +L
Sbjct: 726 LFAIAGGRLIRRIRSMCFEKVVHMEVGWFDEPGNSSGAMGARLSADAALIRTLVGDSLCL 785
Query: 230 GTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTK 289
+ V G + SW++ +++++ P +G+ + K ++ S + E ++
Sbjct: 786 SVKNVASLVTGLIIAFTASWEVAIIILVIIPFIGINGYIQIKFMKGFSADAKAKYEEASQ 845
Query: 290 VSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLA 349
V+ + + + +T+ ++C E+K + Y G+K+ L SG FG++ FV +
Sbjct: 846 VANDAVGSIRTVASFCAEEKVMEMYKKRCEDTIKSGIKQGLISGVGFGISFFVLYSVYAS 905
Query: 350 LLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRK 409
G ++K G D+ + + KG GAA +F + DR
Sbjct: 906 CFYVGARLVKAGRTNFNDVFQVFLALTLTAVGISQASSFAPDSSKGKGAAVSIFRIIDRI 965
Query: 410 PLIHPTIGKDPVTLENKS--IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGG 467
I + + LEN I H+ F+Y TRP +F DL ++R G+ V +VG SG
Sbjct: 966 SKIDSR-DESGMVLENVKGDIELCHISFTYQTRPDVQVFRDLCLSIRAGQTVALVGESGS 1024
Query: 468 GKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYA 527
GKSTV SLL R+YD SG I L ++ L+ R+ +G+V QEP+LF+ TI NI Y
Sbjct: 1025 GKSTVISLLQRFYDPDSGHITLDGVELKKLRLKWLRQQMGLVGQEPVLFNDTIRANIAYG 1084
Query: 528 VPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLD 587
E E I A AN +F+++ G T VG RG QLSGGQKQR+A+ARA + +
Sbjct: 1085 KGGEEAT-EAEIIAASELANAHRFISSIQKGYDTVVGERGIQLSGGQKQRVAIARAIVKE 1143
Query: 588 PSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTV 647
P IL+LDEATSALD++SE VV +L R +TTI +AHR+STI+++ VI + ++G +
Sbjct: 1144 PKILLLDEATSALDAESERVVQDAL-DRVMVNRTTIVVAHRLSTIKNAD-VIAVVKNGVI 1201
Query: 648 AETGSFDKLIAI 659
AE G+ + LI I
Sbjct: 1202 AEKGTHETLINI 1213
Score = 266 bits (680), Expect = 8e-71
Identities = 174/519 (33%), Positives = 274/519 (52%), Gaps = 19/519 (3%)
Query: 154 ALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLD-HNRVGDLISRL 212
ALG F+ ++ +TGER AR+R+ +K L QD F D G+++ R+
Sbjct: 85 ALGAAFL--------QVACWMITGERQAARIRSLYLKTILRQDIGFFDVEMTTGEVVGRM 136
Query: 213 SSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFI-SWKLTCVMMLLAPPLGVMALVYGK 271
S D ++ ++ + + + +I FVG +++F+ W LT VM+ P L +
Sbjct: 137 SGDTVLILDAMGEKVGKFIQ-LISTFVGGFVIAFLRGWLLTLVMLTSIPLLAMSGAAIAI 195
Query: 272 RIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALT 331
+ S Q Q + + + V E+ L + +T+ ++ GEK+ + Y + + + +K+
Sbjct: 196 IVTRASSQEQAAYAKASNVVEQTLGSIRTVASFTGEKQAMSSYKELINLAYKSNVKQGFV 255
Query: 332 SGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXE 391
+G GV V G MI T G + + M+ V
Sbjct: 256 TGLGLGVMFLVFFSTYALGTWFGGEMILRKGYTGGAVINVMVTVVSSSIALGQASPCLTA 315
Query: 392 LMKGAGAAARVFELNDRKPLIHPTIGKDPVTLEN--KSIHFNHVKFSYPTRPQHHIFEDL 449
G AA ++FE +R+PLI T + LE+ I V FSYP RP+ +F
Sbjct: 316 FTAGKAAAYKMFETIEREPLID-TFDLNGKVLEDIRGEIELRDVCFSYPARPKEEVFGGF 374
Query: 450 NFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVV 509
+ + G +VG SG GKSTV SL+ R+YD SG++ + ++++F L+ R +G+V
Sbjct: 375 SLLIPSGTTTALVGESGSGKSTVISLIERFYDPNSGQVLIDGVDLKEFQLKWIRGKIGLV 434
Query: 510 QQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQ 569
QEP+LFS +I++NI Y V + I A AN KF+ P GL+T VG GTQ
Sbjct: 435 SQEPVLFSSSIMENIGYGKEGATVEE---IQAASKLANAAKFIDKLPLGLETLVGEHGTQ 491
Query: 570 LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRV 629
LSGGQKQRIA+ARA L DP IL+LDEATSALD++SE VV ++L R +TT+ +AHR+
Sbjct: 492 LSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEAL-DRIMVNRTTVIVAHRL 550
Query: 630 STIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLL 668
ST++++ + V++R G + E GS +L+ + + ++LL
Sbjct: 551 STVRNADIIAVIHR-GKIVEEGSHSELLKDHEGAYSQLL 588
>Hs9955968 [U] KOG0058 Peptide exporter ABC superfamily
Length = 723
Score = 269 bits (688), Expect = 1e-71
Identities = 176/586 (30%), Positives = 299/586 (50%), Gaps = 65/586 (11%)
Query: 75 PHDSKASGWQDIKRLFLLAKPETRSMFXXXXXXXXXXXXXXXVPTVIGKLLDIARXXXXX 134
P +ASG +++L KP+ + +P G+ +D
Sbjct: 164 PPPEQASG-ATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSM 222
Query: 135 XXXXXXTMIFGLTSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALE 194
+I L A+G F G + ++ RL RLR ++ +
Sbjct: 223 DQFSTAVVIVCLL------AIGSSFAAGIRGGIFTLIFA-----RLNIRLRNCLFRSLVS 271
Query: 195 QDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQ--GFVGFGMMSFISWKLT 252
Q+ +F D NR GDLISRL+SD +VS V+QN++ R ++ G V F M +SW+L+
Sbjct: 272 QETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVF--MFSLSWQLS 329
Query: 253 CVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIH 312
V + P + +++ +YGK + LS+++Q ++ + +EE +SA KT++++ E++E
Sbjct: 330 LVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAE 389
Query: 313 RYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFM 372
Y ++++V+ + KEA + +G VG+V
Sbjct: 390 VYLRKLQQVYKLNRKEAAAYMYYVWGSGSVGSV--------------------------- 422
Query: 373 MYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNH 432
LM+G GAA +VFE DR+P + P LE + + F +
Sbjct: 423 ----------------YSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGR-VDFEN 465
Query: 433 VKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGND 492
V F+Y TRP + ++++F++ PG+ +VGPSG GKS+ ++L +Y + G + L
Sbjct: 466 VTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGK 525
Query: 493 NIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFL 552
I ++ + R++ +V QEP+LF+ +I DNI+Y +P + A +AN F+
Sbjct: 526 PISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFE---MVVEAAQKANAHGFI 582
Query: 553 ANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSL 612
DG T G +G QLSGGQKQR+A+ARA + +P +LILDEATSALD++SE ++ Q++
Sbjct: 583 MELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAI 642
Query: 613 QQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
+ + T + IAHR+ST++H+ ++VL++ G V + G+ +L+A
Sbjct: 643 -HGNLQKHTVLIIAHRLSTVEHAHLIVVLDK-GRVVQQGTHQQLLA 686
>CE15714 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1294
Score = 269 bits (687), Expect = 1e-71
Identities = 173/509 (33%), Positives = 277/509 (53%), Gaps = 13/509 (2%)
Query: 152 YTALG-GVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLIS 210
Y LG G+F G L +VI E+L R R + + + Q+ + D N G L +
Sbjct: 109 YVYLGCGIFAAGFLQASCFMVIC----EKLSNRFRRQFFHSVMRQEIAWYDKNTSGTLSN 164
Query: 211 RLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYG 270
+L + V + + + + Q GF + W LT +MM L+P + + L
Sbjct: 165 KLFDNLERVREGTGDKVGLAFQMMAQFIGGFAVAFTYDWLLTLIMMSLSPFMMICGLFLA 224
Query: 271 KRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEAL 330
K + + + ++EE L++ +T+ A+ G++ E RY D + G+K++
Sbjct: 225 KLLATAATKEAKQYAVAGGIAEEVLTSIRTVIAFNGQEYECKRYEDALEHGKKTGIKKSF 284
Query: 331 TSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXX 390
GA + + GT+ + +G + G + + +
Sbjct: 285 LIGAGLASFFVIIYASYCLAFWVGTNFVYSGRLESGTVLTVFFSVMMGSMALGQAGQQFA 344
Query: 391 ELMKGAGAAARVFELNDRKPLI--HPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFED 448
+ GAAA ++E+ DR P I + T G+ P + + I N V+F+YPTR I +
Sbjct: 345 TIGTALGAAASLYEVIDRIPEIDAYSTEGQTPSKISGR-ISVNKVEFTYPTRADVKILKG 403
Query: 449 LNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGV 508
++ +PG+ V +VG SG GKST+ LL R+Y+ +G+I + + I DFN++ R+L+GV
Sbjct: 404 VSLDAQPGQTVALVGSSGCGKSTIIQLLQRFYNPDAGQILIDDIPIEDFNIKYLRQLVGV 463
Query: 509 VQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGT 568
V QEP LF+ +I NI Y + V+DE I+RA+ +AN F+ FP+GL T VG RG
Sbjct: 464 VSQEPNLFNTSIEQNIRYG--RSDVSDED-IARALKEANAADFIKTFPEGLNTLVGDRGV 520
Query: 569 QLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHR 628
Q+SGGQKQRIA+ARA + +P IL+LDEATSALD++SE +V QS + ++RG+TTI IAHR
Sbjct: 521 QMSGGQKQRIAIARALVRNPKILLLDEATSALDAESESIV-QSALENASRGRTTIVIAHR 579
Query: 629 VSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ST++++ ++IV+ + G V E G+ + LI
Sbjct: 580 LSTVRNADKIIVM-KAGQVMEVGTHETLI 607
Score = 236 bits (603), Expect = 7e-62
Identities = 156/493 (31%), Positives = 258/493 (51%), Gaps = 17/493 (3%)
Query: 175 VTGERLVARLRTRTMKAALEQDATFLD--HNRVGDLISRLSSDAGIVSKSVTQNLSDGTR 232
V ERL R+R++ + L QDAT+ D + G + +RL++DA + ++ L
Sbjct: 773 VAAERLTMRIRSKVYRNVLRQDATYFDMPKHSPGRITTRLATDAPNIKSAIDYRLGSIFN 832
Query: 233 AVIQGFVGFGMMSFISWKLTCVMMLLAPPLGV----MALVYGKRIRNLSRQLQTSVGELT 288
A+ G G+ + W++ ++M + P + V M +G + +++++ +
Sbjct: 833 AIASVGGGLGIAFYYGWQMAFLVMAIFPFMAVGQALMMKYHGGSATSDAKEMENA----G 888
Query: 289 KVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALL 348
K + E + +T+QA + K + + + + +A+ G +G +
Sbjct: 889 KTAMEAIENIRTVQALTLQTKLYNIFCSHLDAPHGGNISKAIIRGLTYGFANSIQFFTYA 948
Query: 349 ALLLTGTSMI--KTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELN 406
A G +I K LM ++ + E +K AA +F +
Sbjct: 949 AAFRFGLFLIFDKNVLMEPENVLRVLFAISFSFGTIGFAASYFPEYIKATFAAGLIFNML 1008
Query: 407 DRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSG 466
+ +P I + + N V F YP RP I + LN V+PG+ + +VGPSG
Sbjct: 1009 EEEPRIDGMTSSGTYPQLSGEVKLNKVFFRYPERPAVPILQGLNVHVKPGQTLALVGPSG 1068
Query: 467 GGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITY 526
GKSTV SLL R YD G + + N+++R N + R+ + +V QEP+LF +I +NI Y
Sbjct: 1069 CGKSTVISLLERLYDPLEGAVTVDNNDLRQMNPKHLRKHIALVSQEPILFDTSIRENIVY 1128
Query: 527 AV-PQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFL 585
+ P E +++ I A +AN KF+ PDG +T VG +GTQLSGGQKQRIA+ARA +
Sbjct: 1129 GLQPGEYTHEQ--IETACSKANIHKFIDELPDGYETRVGEKGTQLSGGQKQRIAIARALI 1186
Query: 586 LDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHG 645
+P IL+LDEATSALD++SE+ V +L +A+ +T I +AHR+STI ++ ++V+ ++G
Sbjct: 1187 RNPKILLLDEATSALDTESEKQVQVAL-DAAAKDRTCIVVAHRLSTIVNAGCIMVV-KNG 1244
Query: 646 TVAETGSFDKLIA 658
V E G+ ++LIA
Sbjct: 1245 QVVEQGTHNELIA 1257
>At3g28860 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1252
Score = 268 bits (684), Expect = 3e-71
Identities = 166/504 (32%), Positives = 264/504 (51%), Gaps = 13/504 (2%)
Query: 160 VVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHN-RVGDLISRLSSDAGI 218
+V ++ I +GER VA LR + ++A L+QD F D + R GD++ +S+D +
Sbjct: 95 LVVCFSSYAEIACWMYSGERQVAALRKKYLEAVLKQDVGFFDTDARTGDIVFSVSTDTLL 154
Query: 219 VSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSR 278
V ++++ + + + G + +WKL + + + P + +Y + ++
Sbjct: 155 VQDAISEKVGNFIHYLSTFLAGLVVGFVSAWKLALLSVAVIPGIAFAGGLYAYTLTGITS 214
Query: 279 QLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGV 338
+ + S ++E+ ++ +T+ +Y GE K ++ Y+D ++ +G K + G G
Sbjct: 215 KSRESYANAGVIAEQAIAQVRTVYSYVGESKALNAYSDAIQYTLKLGYKAGMAKGLGLGC 274
Query: 339 TGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGA 398
T + ++ + I+ G G + + A+ KG A
Sbjct: 275 TYGIACMSWALVFWYAGVFIRNGQTDGGKAFTAIFSAIVGGMSLGQSFSNLGAFSKGKAA 334
Query: 399 AARVFELNDRKPLI--HPTIGK--DPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVR 454
++ E+ +++P I P GK D V + +I F V FSYP+RP IF + N
Sbjct: 335 GYKLMEIINQRPTIIQDPLDGKCLDQV---HGNIEFKDVTFSYPSRPDVMIFRNFNIFFP 391
Query: 455 PGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPM 514
G+ V +VG SG GKSTV SL+ R+YD SG+I L I+ L+ R +G+V QEP
Sbjct: 392 SGKTVAVVGGSGSGKSTVVSLIERFYDPNSGQILLDGVEIKTLQLKFLREQIGLVNQEPA 451
Query: 515 LFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQ 574
LF+ TIL+NI Y P + + A AN F+ P G T VG RG QLSGGQ
Sbjct: 452 LFATTILENILYGKPDATM---VEVEAAASAANAHSFITLLPKGYDTQVGERGVQLSGGQ 508
Query: 575 KQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQH 634
KQRIA+ARA L DP IL+LDEATSALD+ SE +V ++L R G+TT+ +AHR+ TI++
Sbjct: 509 KQRIAIARAMLKDPKILLLDEATSALDASSESIVQEAL-DRVMVGRTTVVVAHRLCTIRN 567
Query: 635 SSRVIVLNRHGTVAETGSFDKLIA 658
+ V+ + G V ETG+ ++LIA
Sbjct: 568 VDSIAVI-QQGQVVETGTHEELIA 590
Score = 260 bits (665), Expect = 4e-69
Identities = 162/520 (31%), Positives = 274/520 (52%), Gaps = 16/520 (3%)
Query: 158 VFVVGALANVGRIVI----LKVTGERLVARLRTRTMKAALEQDATFLDHNRVGD--LISR 211
+++ L VG +I + GE L R+R + A L + + D + + +R
Sbjct: 733 IYIGAGLYAVGAYLIQHYFFSIMGENLTTRVRRMMLSAILRNEVGWFDEDEHNSSLIAAR 792
Query: 212 LSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGK 271
L++DA V ++ + +S + + F + + W+++ +++ P L +
Sbjct: 793 LATDAADVKSAIAERISVILQNMTSLLTSFIVAFIVEWRVSLLILGTFPLLVLANFAQQL 852
Query: 272 RIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALT 331
++ + + + + ++ E +S +T+ A+ + K + + E+R L + T
Sbjct: 853 SLKGFAGDTAKAHAKTSMIAGEGVSNIRTVAAFNAQSKILSLFCHELRVPQKRSLYRSQT 912
Query: 332 SGAFFGVT--GFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXX 389
SG FG++ G+ AL+ L G ++ G+ T + + V
Sbjct: 913 SGFLFGLSQLALYGSEALI--LWYGAHLVSKGVSTFSKVIKVFVVLVITANSVAETVSLA 970
Query: 390 XELMKGAGAAARVFELNDRKPLIHPT-IGKDPVTLENKSIHFNHVKFSYPTRPQHHIFED 448
E+++G A VF + DR+ I P DPV I F HV F+YP+RP +F D
Sbjct: 971 PEIIRGGEAVGSVFSVLDRQTRIDPDDADADPVETIRGDIEFRHVDFAYPSRPDVMVFRD 1030
Query: 449 LNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGV 508
N +R G +VG SG GKS+V +++ R+YD +G++ + +IR NL+ R +G+
Sbjct: 1031 FNLRIRAGHSQALVGASGSGKSSVIAMIERFYDPLAGKVMIDGKDIRRLNLKSLRLKIGL 1090
Query: 509 VQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGT 568
VQQEP LF+ TI DNI Y E+ + A AN F++ P+G +T VG RG
Sbjct: 1091 VQQEPALFAATIFDNIAYGKDGA---TESEVIDAARAANAHGFISGLPEGYKTPVGERGV 1147
Query: 569 QLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHR 628
QLSGGQKQRIA+ARA L +P++L+LDEATSALD++SE V+ ++L +R RG+TT+ +AHR
Sbjct: 1148 QLSGGQKQRIAIARAVLKNPTVLLLDEATSALDAESECVLQEAL-ERLMRGRTTVVVAHR 1206
Query: 629 VSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLL 668
+STI+ + V+ + G + E GS +L++ P+ + ++LL
Sbjct: 1207 LSTIRGVDCIGVI-QDGRIVEQGSHSELVSRPEGAYSRLL 1245
>CE28355 [U] KOG0058 Peptide exporter ABC superfamily
Length = 787
Score = 267 bits (682), Expect = 5e-71
Identities = 167/536 (31%), Positives = 287/536 (53%), Gaps = 14/536 (2%)
Query: 142 MIFGLTSTQFYTALGGVFVVGALANVGRIVILKVTG-------ERLVARLRTRTMKAALE 194
+I + +T+ Y AL + + ++ V G R+ +R ++
Sbjct: 206 VIATVVATKSYPALSNAVYIMTIISLVSAVAAGFRGGSFEYAYARIQRAIRYDLFHGLVK 265
Query: 195 QDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCV 254
QD F D ++ G++ SRL++D +S +V N++ R + M +SW+L+ V
Sbjct: 266 QDVAFYDAHKTGEVTSRLAADCQTMSDTVALNVNVFLRNCVMLLGSMIFMMKLSWRLSLV 325
Query: 255 MMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRY 314
+L P + V + ++G LS + Q ++ E V+EE LS +T++++ E E R+
Sbjct: 326 TFILVPIIFVASKIFGTYYDLLSERTQDTIAESNDVAEEVLSTMRTVRSFSCENVEADRF 385
Query: 315 ADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMY 374
++ V +A+ F V+ + ++++L G ++ T M L SF++Y
Sbjct: 386 YGKLTHTLDVTRTKAIAYIGFLWVSELFQSFIIVSVLWYGGHLVLTQKMKGDLLVSFLLY 445
Query: 375 AVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVK 434
+ LM+ GA+ +VFE DR+P I P + K I F +V
Sbjct: 446 QMQLGDNLRQMGEVWTGLMQSVGASRKVFEYIDREPQIQHNGEYMPENVVGK-IEFRNVH 504
Query: 435 FSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNI 494
FSYPTR I +DL+FTV PGE V +VGPSG GKS+ SLL +Y +G++ + +
Sbjct: 505 FSYPTRSDQPILKDLSFTVEPGETVALVGPSGSGKSSCISLLENFYVPNAGQVLVDGVPL 564
Query: 495 RDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLAN 554
+F + + +V QEP+LF+ ++++N+ Y V +T I R+ AN F+
Sbjct: 565 EEFEHHYIHKKIALVGQEPVLFARSVMENVRYGVEVA----DTEIIRSCEMANAHGFIMQ 620
Query: 555 FPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQ 614
+T VG +GTQ+SGGQKQRIA+ARA + +P+IL+LDEATSALD++SE +V +++
Sbjct: 621 TTLKYETNVGEKGTQMSGGQKQRIAIARALVREPAILLLDEATSALDTESEHLVQEAI-Y 679
Query: 615 RSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
++ GK+ I IAHR+ST++ + +++V+N+ G V + G+ + L+ + + KL+ +
Sbjct: 680 KNLDGKSVILIAHRLSTVEKADKIVVINK-GRVEQIGNHETLLKDTNGTYAKLVQR 734
>At2g36910 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1286
Score = 267 bits (682), Expect = 5e-71
Identities = 171/499 (34%), Positives = 270/499 (53%), Gaps = 11/499 (2%)
Query: 176 TGERLVARLRTRTMKAALEQDATFLDHN-RVGDLISRLSSDAGIVSKSVTQNLSDGTRAV 234
+GER ++R + ++AAL QD F D R D++ +++DA +V ++++ L + +
Sbjct: 114 SGERQTTKMRIKYLEAALNQDIQFFDTEVRTSDVVFAINTDAVMVQDAISEKLGNFIHYM 173
Query: 235 IQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQ 294
GF + W+L V + + P + V+ ++ + LS + Q S+ + + E+
Sbjct: 174 ATFVSGFIVGFTAVWQLALVTLAVVPLIAVIGGIHTTTLSKLSNKSQESLSQAGNIVEQT 233
Query: 295 LSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTG 354
+ + + A+ GE + Y+ ++ +G K L G G T FV LL G
Sbjct: 234 VVQIRVVMAFVGESRASQAYSSALKIAQKLGYKTGLAKGMGLGATYFVVFCCYALLLWYG 293
Query: 355 TSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXX-XXXELMKGAGAAARVFELNDRKPLIH 413
+++ L T G L+ M+AV K AAA++F + D KP I
Sbjct: 294 GYLVRHHL-TNGGLAIATMFAVMIGGLALGQSAPSMAAFAKAKVAAAKIFRIIDHKPTIE 352
Query: 414 PTIGKDPVTLENKS--IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKST 471
+ V L++ + + +V FSYP+RP I + +V G+ + +VG SG GKST
Sbjct: 353 RN-SESGVELDSVTGLVELKNVDFSYPSRPDVKILNNFCLSVPAGKTIALVGSSGSGKST 411
Query: 472 VASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQE 531
V SL+ R+YD SG++ L +++ LR R+ +G+V QEP LF+ +I +NI P
Sbjct: 412 VVSLIERFYDPNSGQVLLDGQDLKTLKLRWLRQQIGLVSQEPALFATSIKENILLGRPDA 471
Query: 532 LVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSIL 591
D+ I A AN F+ PDG T VG RG QLSGGQKQRIA+ARA L +P+IL
Sbjct: 472 ---DQVEIEEAARVANAHSFIIKLPDGFDTQVGERGLQLSGGQKQRIAIARAMLKNPAIL 528
Query: 592 ILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETG 651
+LDEATSALDS+SE++V ++L R G+TT+ IAHR+STI+ + V VL + G+V+E G
Sbjct: 529 LLDEATSALDSESEKLVQEAL-DRFMIGRTTLIIAHRLSTIRKADLVAVL-QQGSVSEIG 586
Query: 652 SFDKLIAIPDSSLNKLLSK 670
+ D+L + ++ + L K
Sbjct: 587 THDELFSKGENGVYAKLIK 605
Score = 241 bits (614), Expect = 4e-63
Identities = 155/490 (31%), Positives = 249/490 (50%), Gaps = 15/490 (3%)
Query: 175 VTGERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSSDAGIVSKSVTQNLSDGTR 232
+ GE L R+R + + A L+ + + D N + +RL+ DA V ++ +S +
Sbjct: 767 IVGENLTKRVREKMLSAVLKNEMAWFDQEENESARIAARLALDANNVRSAIGDRISVIVQ 826
Query: 233 AVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSE 292
V + W+L V++ + P + ++ + S L+ + + T+++
Sbjct: 827 NTALMLVACTAGFVLQWRLALVLVAVFPVVVAATVLQKMFMTGFSGDLEAAHAKGTQLAG 886
Query: 293 EQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLL 352
E ++ +T+ A+ E K + Y + + +G+ +GV F + L
Sbjct: 887 EAIANVRTVAAFNSEAKIVRLYTANLEPPLKRCFWKGQIAGSGYGVAQFCLYASYALGLW 946
Query: 353 TGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLI 412
+ ++K G+ M + + +KG A VFEL DRK I
Sbjct: 947 YASWLVKHGISDFSKTIRVFMVLMVSANGAAETLTLAPDFIKGGQAMRSVFELLDRKTEI 1006
Query: 413 HPTIGKDPVTLE-----NKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGG 467
P DP T + H+ FSYP+RP IF DL+ R G+ + +VGPSG
Sbjct: 1007 EPD---DPDTTPVPDRLRGEVELKHIDFSYPSRPDIQIFRDLSLRARAGKTLALVGPSGC 1063
Query: 468 GKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYA 527
GKS+V SL+ R+Y+ SG + + +IR +NL+ R+ + +V QEP LF TI +NI Y
Sbjct: 1064 GKSSVISLIQRFYEPSSGRVMIDGKDIRKYNLKAIRKHIAIVPQEPCLFGTTIYENIAYG 1123
Query: 528 VPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLD 587
E I +A A+ KF++ P+G +T VG RG QLSGGQKQRIA+ARA +
Sbjct: 1124 ---HECATEAEIIQAATLASAHKFISALPEGYKTYVGERGVQLSGGQKQRIAIARALVRK 1180
Query: 588 PSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTV 647
I++LDEATSALD++SE V ++L Q + G+T+I +AHR+STI+++ + V++ G V
Sbjct: 1181 AEIMLLDEATSALDAESERSVQEALDQ-ACSGRTSIVVAHRLSTIRNAHVIAVID-DGKV 1238
Query: 648 AETGSFDKLI 657
AE GS L+
Sbjct: 1239 AEQGSHSHLL 1248
>Hs21536378 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1321
Score = 266 bits (680), Expect = 8e-71
Identities = 163/514 (31%), Positives = 266/514 (51%), Gaps = 15/514 (2%)
Query: 150 QFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLI 209
+F + G+ V + +I + R + ++R + + + + D N VG+L
Sbjct: 140 KFASYYAGIAVAVLITGYIQICFWVIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELN 199
Query: 210 SRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVY 269
+R S D ++ ++ ++ + + GF + F WKLT V++ ++P +G+ A
Sbjct: 200 TRFSDDINKINDAIADQMALFIQRMTSTICGFLLGFFRGWKLTLVIISVSPLIGIGAATI 259
Query: 270 GKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEA 329
G + + + + V++E +S+ +T+ A+ GEK+E+ RY + G+++
Sbjct: 260 GLSVSKFTDYELKAYAKAGVVADEVISSMRTVAAFGGEKREVERYEKNLVFAQRWGIRKG 319
Query: 330 LTSGAFFGVTGFVGNVALLALLLT----GTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXX 385
+ G F TGFV + L L T ++ G T G L + +
Sbjct: 320 IVMGFF---TGFVWCLIFLCYALAFWYGSTLVLDEGEYTPGTLVQIFLSVIVGALNLGNA 376
Query: 386 XXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLEN--KSIHFNHVKFSYPTRPQH 443
G AA +FE DRKP+I + +D L+ I F++V F YP+RP+
Sbjct: 377 SPCLEAFATGRAAATSIFETIDRKPIID-CMSEDGYKLDRIKGEIEFHNVTFHYPSRPEV 435
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYR 503
I DLN ++PGE +VGPSG GKST L+ R+YD G + + +IR N++ R
Sbjct: 436 KILNDLNMVIKPGEMTALVGPSGAGKSTALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLR 495
Query: 504 RLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTV 563
+G+V+QEP+LFS TI +NI Y + D I +A +AN F+ + P T V
Sbjct: 496 DQIGIVEQEPVLFSTTIAENIRYGREDATMED---IVQAAKEANAYNFIMDLPQQFDTLV 552
Query: 564 GPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTI 623
G G Q+SGGQKQR+A+ARA + +P IL+LD ATSALD++SE +V Q + + G T I
Sbjct: 553 GEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMV-QEVLSKIQHGHTII 611
Query: 624 SIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
S+AHR+ST++ + +I HGT E G+ ++L+
Sbjct: 612 SVAHRLSTVRAADTIIGF-EHGTAVERGTHEELL 644
Score = 224 bits (572), Expect = 3e-58
Identities = 155/491 (31%), Positives = 252/491 (50%), Gaps = 16/491 (3%)
Query: 176 TGERLVARLRTRTMKAALEQDATFLD--HNRVGDLISRLSSDA----GIVSKSVTQNLSD 229
+GE L RLR +A L QD + D N G L +RL++DA G + ++
Sbjct: 823 SGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTRLATDASQVQGAAGSQIGMIVNS 882
Query: 230 GTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTK 289
T + + F SWKL+ V++ P L + + + + + + ++ + +
Sbjct: 883 FTNVTVAMIIAFSF----SWKLSLVILCFFPFLALSGATQTRMLTGFASRDKQALEMVGQ 938
Query: 290 VSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLA 349
++ E LS +T+ E++ I E+ K F +++A G F + +A A
Sbjct: 939 ITNEALSNIRTVAGIGKERRFIEALETELEKPFKTAIQKANIYGFCFAFAQCIMFIANSA 998
Query: 350 LLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRK 409
G +I + + + V K +AAR F+L DR+
Sbjct: 999 SYRYGGYLISNEGLHFSYVFRVISAVVLSATALGRAFSYTPSYAKAKISAARFFQLLDRQ 1058
Query: 410 PLI--HPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGG 467
P I + T G+ + K I F KF+YP+RP + L+ ++ PG+ + VG SG
Sbjct: 1059 PPISVYNTAGEKWDNFQGK-IDFVDCKFTYPSRPDSQVLNGLSVSISPGQTLAFVGSSGC 1117
Query: 468 GKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYA 527
GKST LL R+YD G++ + + + N++ R +G+V QEP+LF+ +I+DNI Y
Sbjct: 1118 GKSTSIQLLERFYDPDQGKVMIDGHDSKKVNVQFLRSNIGIVSQEPVLFACSIMDNIKYG 1177
Query: 528 VPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLD 587
+ + E R+ A QA F+ + P+ +T VG +G+QLS G+KQRIA+ARA + D
Sbjct: 1178 DNTKEIPME-RVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRD 1236
Query: 588 PSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTV 647
P IL+LDEATSALD++SE+ V +L ++ G+T I IAHR+STIQ++ +I + G V
Sbjct: 1237 PKILLLDEATSALDTESEKTVQVAL-DKAREGRTCIVIAHRLSTIQNAD-IIAVMAQGVV 1294
Query: 648 AETGSFDKLIA 658
E G+ ++L+A
Sbjct: 1295 IEKGTHEELMA 1305
>At1g10680 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1227
Score = 266 bits (680), Expect = 8e-71
Identities = 160/497 (32%), Positives = 278/497 (55%), Gaps = 15/497 (3%)
Query: 176 TGERLVARLRTRTMKAALEQDATFLDHN-RVGDLISRLSSDAGIVSKSVTQNLSDGTRAV 234
TGER A++R +++ L QD + D G++IS ++S+ +V ++++ + + +
Sbjct: 111 TGERQAAKIRKAYLRSMLSQDISLFDTEISTGEVISAITSEILVVQDAISEKVGNFMHFI 170
Query: 235 IQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQ 294
+ GF + W+++ V + + P + + +Y L +++ S + +++EE
Sbjct: 171 SRFIAGFAIGFASVWQISLVTLSIVPFIALAGGIYAFVSSGLIVRVRKSYVKANEIAEEV 230
Query: 295 LSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTG 354
+ +T+QA+ GE+K + Y +R ++ G K L G G FV ++ L+
Sbjct: 231 IGNVRTVQAFTGEEKAVSSYQGALRNTYNYGRKAGLAKGLGLGSLHFVLFLSWALLIWFT 290
Query: 355 TSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHP 414
+ ++ G+ G+ + M+ V M+ + AA +F++ +R
Sbjct: 291 SIVVHKGIANGGESFTTMLNVVIAGLSLGQAAPDISTFMRASAAAYPIFQMIERNT--ED 348
Query: 415 TIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVAS 474
G+ + N I F V F+YP+RP IF+ LNF + G+ V +VG SG GKST+ S
Sbjct: 349 KTGRKLGNV-NGDILFKDVTFTYPSRPDVVIFDKLNFVIPAGKVVALVGGSGSGKSTMIS 407
Query: 475 LLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYA---VPQE 531
L+ R+Y+ G + L ++IR +L+ R +G+V QEP+LF+ TI +NI Y E
Sbjct: 408 LIERFYEPTDGAVMLDGNDIRYLDLKWLRGHIGLVNQEPVLFATTIRENIMYGKDDATSE 467
Query: 532 LVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSIL 591
+ + ++S AI F+ N P+G +T VG RG QLSGGQKQRI+++RA + +PSIL
Sbjct: 468 EITNAAKLSEAI------SFINNLPEGFETQVGERGIQLSGGQKQRISISRAIVKNPSIL 521
Query: 592 ILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETG 651
+LDEATSALD++SE++V ++L R G+TT+ +AHR+ST++++ + V+ G + E+G
Sbjct: 522 LLDEATSALDAESEKIVQEAL-DRVMVGRTTVVVAHRLSTVRNADIIAVVG-GGKIIESG 579
Query: 652 SFDKLIAIPDSSLNKLL 668
S D+LI+ PD + + LL
Sbjct: 580 SHDELISNPDGAYSSLL 596
Score = 254 bits (650), Expect = 2e-67
Identities = 169/501 (33%), Positives = 265/501 (52%), Gaps = 16/501 (3%)
Query: 175 VTGERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSSDAGIVSKSVTQN---LSD 229
+ GERL R+R + A L + + D N L SRL SDA ++ V L +
Sbjct: 728 IMGERLTLRVRQKMFSAILRNEIGWFDKVDNTSSMLASRLESDATLLRTIVVDRSTILLE 787
Query: 230 GTRAVIQGFVGFGMMSFI-SWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELT 288
V+ F+ +SFI +W+LT V++ P + + ++ L + +
Sbjct: 788 NLGLVVTAFI----ISFILNWRLTLVVLATYPLIISGHISEKIFMQGYGGNLSKAYLKAN 843
Query: 289 KVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALL 348
++ E +S +T+ A+C E+K + Y+ E+ + + +G +GV+ F +
Sbjct: 844 MLAGESISNIRTVVAFCAEEKVLDLYSKELLEPSERSFRRGQMAGILYGVSQFFIFSSYG 903
Query: 349 ALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDR 408
L G+ +++ GL + + M + +L+KG VFEL DR
Sbjct: 904 LALWYGSILMEKGLSSFESVMKTFMVLIVTALVMGEVLALAPDLLKGNQMVVSVFELLDR 963
Query: 409 KPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGG 468
+ + G++ +E +I V FSYP+RP IF D N V G+ + +VG SG G
Sbjct: 964 RTQVVGDTGEELSNVEG-TIELKGVHFSYPSRPDVTIFSDFNLLVPSGKSMALVGQSGSG 1022
Query: 469 KSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAV 528
KS+V SL+LR+YD +G I + +I+ L+ RR +G+VQQEP LF+ TI +NI Y
Sbjct: 1023 KSSVLSLVLRFYDPTAGIIMIDGQDIKKLKLKSLRRHIGLVQQEPALFATTIYENILYGK 1082
Query: 529 PQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDP 588
E+ + A AN F+++ P+G T VG RG Q+SGGQ+QRIA+ARA L +P
Sbjct: 1083 EGA---SESEVMEAAKLANAHSFISSLPEGYSTKVGERGIQMSGGQRQRIAIARAVLKNP 1139
Query: 589 SILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVA 648
IL+LDEATSALD +SE VV Q+L R R +TT+ +AHR+STI++S + V+ + G +
Sbjct: 1140 EILLLDEATSALDVESERVVQQAL-DRLMRDRTTVVVAHRLSTIKNSDMISVI-QDGKII 1197
Query: 649 ETGSFDKLIAIPDSSLNKLLS 669
E GS + L+ + +KL+S
Sbjct: 1198 EQGSHNILVENKNGPYSKLIS 1218
>HsM4502457 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1321
Score = 265 bits (677), Expect = 2e-70
Identities = 162/514 (31%), Positives = 266/514 (51%), Gaps = 15/514 (2%)
Query: 150 QFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLI 209
+F + G+ V + +I + R + ++R + + + + D N VG+L
Sbjct: 140 KFASYYAGIAVAVLITGYIQICFWVIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELN 199
Query: 210 SRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVY 269
+R S D ++ ++ ++ + + GF + F WKLT V++ ++P +G+ A
Sbjct: 200 TRFSDDINKINDAIADQMALFIQRMTSTICGFLLGFFRGWKLTLVIISVSPLIGIGAATI 259
Query: 270 GKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEA 329
G + + + + V++E +S+ +T+ A+ GEK+E+ RY + G+++
Sbjct: 260 GLSVSKFTDYELKAYAKAGVVADEVISSMRTVAAFGGEKREVERYEKNLVFAQRWGIRKG 319
Query: 330 LTSGAFFGVTGFVGNVALLALLLT----GTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXX 385
+ G F TGFV + L + T ++ G T G L + +
Sbjct: 320 IVMGFF---TGFVWCLIFLCYAVAFWYGSTLVLDEGEYTPGTLVQIFLSVIVGALNLGNA 376
Query: 386 XXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLEN--KSIHFNHVKFSYPTRPQH 443
G AA +FE DRKP+I + +D L+ I F++V F YP+RP+
Sbjct: 377 SPCLEAFATGRAAATSIFETIDRKPIID-CMSEDGYKLDRIKGEIEFHNVTFHYPSRPEV 435
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYR 503
I DLN ++PGE +VGPSG GKST L+ R+YD G + + +IR N++ R
Sbjct: 436 KILNDLNMVIKPGEMTALVGPSGAGKSTALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLR 495
Query: 504 RLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTV 563
+G+V+QEP+LFS TI +NI Y + D I +A +AN F+ + P T V
Sbjct: 496 DQIGIVEQEPVLFSTTIAENIRYGREDATMED---IVQAAKEANAYNFIMDLPQQFDTLV 552
Query: 564 GPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTI 623
G G Q+SGGQKQR+A+ARA + +P IL+LD ATSALD++SE +V Q + + G T I
Sbjct: 553 GEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMV-QEVLSKIQHGHTII 611
Query: 624 SIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
S+AHR+ST++ + +I HGT E G+ ++L+
Sbjct: 612 SVAHRLSTVRAADTIIGF-EHGTAVERGTHEELL 644
Score = 224 bits (572), Expect = 3e-58
Identities = 155/491 (31%), Positives = 252/491 (50%), Gaps = 16/491 (3%)
Query: 176 TGERLVARLRTRTMKAALEQDATFLD--HNRVGDLISRLSSDA----GIVSKSVTQNLSD 229
+GE L RLR +A L QD + D N G L +RL++DA G + ++
Sbjct: 823 SGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTRLATDASQVQGAAGSQIGMIVNS 882
Query: 230 GTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTK 289
T + + F SWKL+ V++ P L + + + + + + ++ + +
Sbjct: 883 FTNVTVAMIIAFSF----SWKLSLVILCFFPFLALSGATQTRMLTGFASRDKQALEMVGQ 938
Query: 290 VSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLA 349
++ E LS +T+ E++ I E+ K F +++A G F + +A A
Sbjct: 939 ITNEALSNIRTVAGIGKERRFIEALETELEKPFKTAIQKANIYGFCFAFAQCIMFIANSA 998
Query: 350 LLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRK 409
G +I + + + V K +AAR F+L DR+
Sbjct: 999 SYRYGGYLISNEGLHFSYVFRVISAVVLSATALGRAFSYTPSYAKAKISAARFFQLLDRQ 1058
Query: 410 PLI--HPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGG 467
P I + T G+ + K I F KF+YP+RP + L+ ++ PG+ + VG SG
Sbjct: 1059 PPISVYNTAGEKWDNFQGK-IDFVDCKFTYPSRPDSQVLNGLSVSISPGQTLAFVGSSGC 1117
Query: 468 GKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYA 527
GKST LL R+YD G++ + + + N++ R +G+V QEP+LF+ +I+DNI Y
Sbjct: 1118 GKSTSIQLLERFYDPDQGKVMIDGHDSKKVNVQFLRSNIGIVSQEPVLFACSIMDNIKYG 1177
Query: 528 VPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLD 587
+ + E R+ A QA F+ + P+ +T VG +G+QLS G+KQRIA+ARA + D
Sbjct: 1178 DNTKEIPME-RVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRD 1236
Query: 588 PSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTV 647
P IL+LDEATSALD++SE+ V +L ++ G+T I IAHR+STIQ++ +I + G V
Sbjct: 1237 PKILLLDEATSALDTESEKTVQVAL-DKAREGRTCIVIAHRLSTIQNAD-IIAVMAQGVV 1294
Query: 648 AETGSFDKLIA 658
E G+ ++L+A
Sbjct: 1295 IEKGTHEELMA 1305
>CE23999 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1269
Score = 265 bits (677), Expect = 2e-70
Identities = 162/492 (32%), Positives = 265/492 (52%), Gaps = 13/492 (2%)
Query: 172 ILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGT 231
I+K G+ R+R + + L +DA + D+ G L + L+ + + + ++
Sbjct: 123 IMKYVGDNTTYRVRKQYISRLLRKDAEYFDNVSTGHLSTVLNDNLERFREVFNEKIALIF 182
Query: 232 RAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVS 291
+ VG + + W+L + + + + + + + T ++
Sbjct: 183 ALLTDFVVGTALAFYTDWRLASYGIFFSLGIAFSGFINSAGVMKTTGKQNTHYANAGSIA 242
Query: 292 EEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALL 351
+ L A KT+ + G+ EI RY +E++ G+ AL G T F N +L
Sbjct: 243 FQTLGAYKTVCSLNGQNTEIERYTEELKAGEKYGIHRALMYSISRGFTYFFCNSLNTVIL 302
Query: 352 LTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPL 411
G +MI +G + + Y + L + A + E+ ++
Sbjct: 303 YVGANMIYSGSLEPAVVVRIFHYMMFGAFCLSEALPHISRLAGAISSTAPIAEMLIKEDN 362
Query: 412 IHPTIGKDPVTLE-----NKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSG 466
+ I KD + N +I F +VKFSYPTRP + + ++F V+ GE + +VG SG
Sbjct: 363 V---IEKDETDYDVEVEVNGNISFKNVKFSYPTRPDAQVLKGISFDVQNGECIALVGASG 419
Query: 467 GGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITY 526
GKSTV LLL YY+I SG I + ++ D N+++ RR++GVV QEP+LF+ TI +NI +
Sbjct: 420 SGKSTVVQLLLHYYNIDSGNIFIDGMDLNDMNIKRLRRVIGVVSQEPVLFNTTIEENIRF 479
Query: 527 AVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLL 586
P + + I A+ +AN F+ +FP G++T VG RGTQLSGGQKQRIA+AR +
Sbjct: 480 GNPNVSLPE---IYGALRKANAYDFVCSFPKGIKTIVGERGTQLSGGQKQRIAIARTLVR 536
Query: 587 DPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGT 646
+P IL+LDEATSALD++SE+VV ++L+ S +G+TTI +AHR+STI+++S++IV+ + G
Sbjct: 537 NPKILLLDEATSALDNESEQVVQKALENAS-QGRTTIVVAHRLSTIRNASKIIVMQK-GE 594
Query: 647 VAETGSFDKLIA 658
+ E G+ D+LIA
Sbjct: 595 IVEVGNHDELIA 606
Score = 211 bits (536), Expect = 4e-54
Identities = 147/488 (30%), Positives = 235/488 (48%), Gaps = 12/488 (2%)
Query: 178 ERLVARLRTRTMKAALEQDATFLD--HNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVI 235
E+L RLR ++ L F D ++ L +RL++D+ V +V L V+
Sbjct: 764 EQLSTRLRIKSFSHMLSLPCAFYDDPNHSATRLSNRLNTDSSNVKAAVDDRLGCVIMTVV 823
Query: 236 QGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQL 295
+ S WK+T +++ P L + Y ++ + + + E L
Sbjct: 824 AISIAITTASLYCWKMTLEVLIFFPLLYLAEYCYDAATETSIQEDTIAFENSNRTAIEAL 883
Query: 296 SATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGT 355
+T++A E K + ++ ++K+ K A+ GA G++ GT
Sbjct: 884 ENMRTVRALNLEDKIMSLISEHLQKIHKSYFKRAIIQGAANGLSLSCYLFVYSVSFKFGT 943
Query: 356 SMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPT 415
+ + D + + K AA +F L + +
Sbjct: 944 YLALRKEVAPMDTYLILETLSMTANMAGSAAAYLPDYKKAVHAAGLIFHLFTYPATMPFS 1003
Query: 416 IGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASL 475
+E I +V+F Y RP I +N V PG+ + +VGPSG GKST+ SL
Sbjct: 1004 SSDGKKNIEKGEIIGENVQFHYDQRPDRMILNGVNLKVDPGKTLALVGPSGCGKSTIISL 1063
Query: 476 LLRYYDIGSGEI------KLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVP 529
L R+Y GE+ K+ ++N+ D NL R L +V QEP LF+ +I +N+ Y +
Sbjct: 1064 LERFYHAVDGEVVSIDAHKIDSENVEDINLNHLRSNLALVSQEPTLFNCSIRENLLYGLT 1123
Query: 530 QELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPS 589
+ + + + +A+ AN F+ FP GL T VG RG QLSGGQKQRIA+ARA L +P
Sbjct: 1124 RSV--PQLELEKALQTANAFNFVFQFPQGLDTIVGERGAQLSGGQKQRIAIARAILRNPK 1181
Query: 590 ILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAE 649
+L+LDEATSALDS SE+VV +L S R +T+ +AHR+ T+ ++ + VL ++G VAE
Sbjct: 1182 VLLLDEATSALDSDSEKVVQNALDTASER-LSTVVVAHRLLTVVNADSIAVL-KNGKVAE 1239
Query: 650 TGSFDKLI 657
G+ ++L+
Sbjct: 1240 QGTHEELL 1247
>At2g47000 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1286
Score = 265 bits (676), Expect = 2e-70
Identities = 165/511 (32%), Positives = 263/511 (51%), Gaps = 11/511 (2%)
Query: 158 VFVVGALANV----GRIVILKVTGERLVARLRTRTMKAALEQDATFLDH--NRVGDLISR 211
+F+V A++ + + G +LV R+R+ + + + + D N G + +R
Sbjct: 765 IFMVLGFASIIAYPAQTFFFAIAGCKLVQRIRSMCFEKVVHMEVGWFDEPENSSGTIGAR 824
Query: 212 LSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGK 271
LS+DA + V +L+ + + G + W+L V++ + P + + +Y K
Sbjct: 825 LSADAATIRGLVGDSLAQTVQNLSSILAGLIIAFLACWQLAFVVLAMLPLIALNGFLYMK 884
Query: 272 RIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALT 331
++ S + GE ++V+ + + + +T+ ++C E K ++ Y+ + G+++ +
Sbjct: 885 FMKGFSADAKKMYGEASQVANDAVGSIRTVASFCAEDKVMNMYSKKCEGPMKNGIRQGIV 944
Query: 332 SGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXE 391
SG FG + FV + A G ++ G T + +
Sbjct: 945 SGIGFGFSFFVLFSSYAASFYVGARLVDDGKTTFDSVFRVFFALTMAAMAISQSSSLSPD 1004
Query: 392 LMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKS-IHFNHVKFSYPTRPQHHIFEDLN 450
K AAA +F + DR+ I P++ V K I HV F YP RP IF+DL
Sbjct: 1005 SSKADVAAASIFAIMDRESKIDPSVESGRVLDNVKGDIELRHVSFKYPARPDVQIFQDLC 1064
Query: 451 FTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQ 510
++R G+ V +VG SG GKSTV +LL R+YD SGEI L I+ L+ R+ G+V
Sbjct: 1065 LSIRAGKTVALVGESGSGKSTVIALLQRFYDPDSGEITLDGVEIKSLRLKWLRQQTGLVS 1124
Query: 511 QEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQL 570
QEP+LF+ TI NI Y + E+ I + +N F++ G T VG RG QL
Sbjct: 1125 QEPILFNETIRANIAYGKGGDA--SESEIVSSAELSNAHGFISGLQQGYDTMVGERGIQL 1182
Query: 571 SGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVS 630
SGGQKQR+A+ARA + DP +L+LDEATSALD++SE VV +L R +TTI +AHR+S
Sbjct: 1183 SGGQKQRVAIARAIVKDPKVLLLDEATSALDAESERVVQDAL-DRVMVNRTTIVVAHRLS 1241
Query: 631 TIQHSSRVIVLNRHGTVAETGSFDKLIAIPD 661
TI+++ VI + ++G + E G D LI I D
Sbjct: 1242 TIKNAD-VIAVVKNGVIVEKGKHDTLINIKD 1271
Score = 263 bits (671), Expect = 9e-70
Identities = 164/498 (32%), Positives = 271/498 (53%), Gaps = 11/498 (2%)
Query: 175 VTGERLVARLRTRTMKAALEQDATFLD-HNRVGDLISRLSSDAGIVSKSVTQNLSDGTRA 233
++GER AR+R+ +K L QD F D G+++ R+S D ++ ++ + + +
Sbjct: 129 ISGERQAARIRSLYLKTILRQDIAFFDIDTNTGEVVGRMSGDTVLIQDAMGEKVGKAIQ- 187
Query: 234 VIQGFVGFGMMSFI-SWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSE 292
++ FVG +++F+ W LT VM+ P L + + I + + QT+ + V E
Sbjct: 188 LLATFVGGFVIAFVRGWLLTLVMLSSIPLLVMAGALLAIVIAKTASRGQTAYAKAATVVE 247
Query: 293 EQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLL 352
+ + + +T+ ++ GEK+ I Y + + G+ E ++G G V + +
Sbjct: 248 QTIGSIRTVASFTGEKQAISNYNKHLVTAYKAGVIEGGSTGLGLGTLFLVVFCSYALAVW 307
Query: 353 TGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLI 412
G +I T G + + ++ + G AA ++FE +R+P I
Sbjct: 308 YGGKLILDKGYTGGQVLNIIIAVLTGSMSLGQTSPCLSAFAAGQAAAYKMFETIERRPNI 367
Query: 413 --HPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKS 470
+ T GK ++ I V F+YP RP IF + + G V +VG SG GKS
Sbjct: 368 DSYSTNGKVLDDIKG-DIELKDVYFTYPARPDEQIFRGFSLFISSGTTVALVGQSGSGKS 426
Query: 471 TVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQ 530
TV SL+ R+YD +G++ + N+++F L+ R +G+V QEP+LF+ +I DNI Y +
Sbjct: 427 TVVSLIERFYDPQAGDVLIDGINLKEFQLKWIRSKIGLVSQEPVLFTASIKDNIAYG-KE 485
Query: 531 ELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSI 590
+ +E I A AN +KF+ P GL T VG GTQLSGGQKQRIA+ARA L DP I
Sbjct: 486 DATTEE--IKAAAELANASKFVDKLPQGLDTMVGEHGTQLSGGQKQRIAVARAILKDPRI 543
Query: 591 LILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAET 650
L+LDEATSALD++SE VV ++L R +TT+ +AHR+ST++++ + V+++ G + E
Sbjct: 544 LLLDEATSALDAESERVVQEAL-DRIMVNRTTVVVAHRLSTVRNADMIAVIHQ-GKIVEK 601
Query: 651 GSFDKLIAIPDSSLNKLL 668
GS +L+ P+ + ++L+
Sbjct: 602 GSHTELLKDPEGAYSQLI 619
>CE11932 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1321
Score = 263 bits (673), Expect = 5e-70
Identities = 166/483 (34%), Positives = 262/483 (53%), Gaps = 8/483 (1%)
Query: 178 ERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQG 237
E++ RLR +K+ L Q+ ++ D N G L ++L + V + + + + Q
Sbjct: 165 EQMNNRLRREFVKSILRQEISWFDTNHSGTLATKLFDNLERVKEGTGDKIGMAFQYLSQF 224
Query: 238 FVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSA 297
GF + SW+LT VM+ + P + K + + + + KV EE +S+
Sbjct: 225 ITGFIVAFTHSWQLTLVMLAVTPIQALCGFAIAKSMSTFAIRETLRYAKAGKVVEETISS 284
Query: 298 TKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSM 357
+T+ + G + E+ RY+ V + G+ + L G FG ++ G
Sbjct: 285 IRTVVSLNGLRYELERYSTAVEEAKKAGVLKGLFLGISFGAMQASNFISFALAFYIGVGW 344
Query: 358 IKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPT-- 415
+ G + GD+ + + L GAA+ ++E+ DRKP+I +
Sbjct: 345 VHDGSLNFGDMLTTFSSVMMGSMALGLAGPQLAVLGTAQGAASGIYEVLDRKPVIDSSSK 404
Query: 416 IGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASL 475
G+ + ++ I +V F+YP+RP I +N V G+ V +VG SG GKST+ SL
Sbjct: 405 AGRKDMKIKG-DITVENVHFTYPSRPDVPILRGMNLRVNAGQTVALVGSSGCGKSTIISL 463
Query: 476 LLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVND 535
LLRYYD+ G+I + ++RD NL R+ + VV QEP LF+ TI +NI ++ +E +
Sbjct: 464 LLRYYDVLKGKITIDGVDVRDINLEFLRKNVAVVSQEPALFNCTIEENI--SLGKEGITR 521
Query: 536 ETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDE 595
E ++ A AN KF+ P+G T VG RGTQLSGGQKQRIA+ARA + +P IL+LDE
Sbjct: 522 EEMVA-ACKMANAEKFIKTLPNGYNTLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDE 580
Query: 596 ATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDK 655
ATSALD++SE +V Q+L ++A+G+TTI IAHR+STI+++ +I+ ++G V E G
Sbjct: 581 ATSALDAESEGIVQQAL-DKAAKGRTTIIIAHRLSTIRNAD-LIISCKNGQVVEVGDHRA 638
Query: 656 LIA 658
L+A
Sbjct: 639 LMA 641
Score = 234 bits (596), Expect = 4e-61
Identities = 152/489 (31%), Positives = 251/489 (51%), Gaps = 9/489 (1%)
Query: 175 VTGERLVARLRTRTMKAALEQDATFLD--HNRVGDLISRLSSDAGIVSKSVTQNLSDGTR 232
+ E L LR + + L Q F D N G + +RL++D + ++ S
Sbjct: 820 IASESLTRDLRNKLFRNVLSQHIGFFDSPQNASGKISTRLATDVPNLRTAIDFRFSTVIT 879
Query: 233 AVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSE 292
++ G G+ F W++ +++ + P + + G+R + + + + K++
Sbjct: 880 TLVSMVAGIGLAFFYGWQMALLIIAILPIVAFGQYLRGRRFTGKNVKSASEFADSGKIAI 939
Query: 293 EQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLL 352
E + +T+QA E + +++ +KEA G +G V +
Sbjct: 940 EAIENVRTVQALAREDTFYENFCEKLDIPHKEAIKEAFIQGLSYGCASSVLYLLNTCAYR 999
Query: 353 TGTSMIKTGLMTVGDLSSF-MMYAVXXXXXXXXXXXXXX-ELMKGAGAAARVFELNDRKP 410
G ++I T T+ + +MYA+ E K A +F + +
Sbjct: 1000 MGLALIITDPPTMQPMRVLRVMYAITISTSTLGFATSYFPEYAKATFAGGIIFGMLRKIS 1059
Query: 411 LIHP-TIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGK 469
I ++ + L K I F +V+F+YP RP+ I + L+F+V PG+ + +VGPSG GK
Sbjct: 1060 KIDSLSLAGEKKKLYGKVI-FKNVRFAYPERPEIEILKGLSFSVEPGQTLALVGPSGCGK 1118
Query: 470 STVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVP 529
STV +LL R+YD GEI + I+ N R + +V QEP LF +I +NI Y +
Sbjct: 1119 STVVALLERFYDTLGGEIFIDGSEIKTLNPEHTRSQIAIVSQEPTLFDCSIAENIIYGLD 1178
Query: 530 QELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPS 589
V ++ A AN F+A P+G +T VG RGTQLSGGQKQRIA+ARA + +P
Sbjct: 1179 PSSVT-MAQVEEAARLANIHNFIAELPEGFETRVGDRGTQLSGGQKQRIAIARALVRNPK 1237
Query: 590 ILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAE 649
IL+LDEATSALD++SE+VV ++L R+ G+T I IAHR++T+ ++ + V++ +GT+ E
Sbjct: 1238 ILLLDEATSALDTESEKVVQEAL-DRAREGRTCIVIAHRLNTVMNADCIAVVS-NGTIIE 1295
Query: 650 TGSFDKLIA 658
G+ +L++
Sbjct: 1296 KGTHTQLMS 1304
>CE27353 [U] KOG0058 Peptide exporter ABC superfamily
Length = 815
Score = 263 bits (671), Expect = 9e-70
Identities = 169/522 (32%), Positives = 281/522 (53%), Gaps = 33/522 (6%)
Query: 143 IFGLTSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDH 202
+ L ST F GG F A A + R ++R ++ ++Q+ F D
Sbjct: 252 MLSLASTVFGGLRGGSFTY-AHATIDR-------------QIRNDLFRSVVKQEIGFFDM 297
Query: 203 NRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPL 262
N+ G++ SRLS+D +S +++ ++ TR + F M +SWKL+ + ++ P +
Sbjct: 298 NKTGEICSRLSADCQTMSNTLSLYMNVLTRNLTMLFGSLIFMFTLSWKLSMITLINIPII 357
Query: 263 GVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVF 322
++ ++G LS + Q SV + V+EE LS+ +T++++ E E R+ +
Sbjct: 358 FLVNKIFGVWYDMLSEETQNSVAKANDVAEEVLSSIRTVKSFACENYESSRFMTFLNVTL 417
Query: 323 HVGLKEALTSGAFFGVTGFVGNVALLAL------LLTGTSMIKTGLMTVGDLSSFMMYAV 376
+ ++ F V G + + LL + L G ++ + G L SF++Y
Sbjct: 418 KIATRKV------FVVIGLIWSNELLQMGILTIVLWYGGHLVIENKVESGLLVSFLLYQF 471
Query: 377 XXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFS 436
LM+ GA+ +VFE DR P + T P + K I F HV FS
Sbjct: 472 QLGENLRELGEVWNGLMQAVGASRKVFEFIDRPPRVENTGTYAPDGMTGK-IEFRHVAFS 530
Query: 437 YPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRD 496
YP RP I EDL FTV PGE V +VGPSGGGKS+ ++L +Y+ SGE+ + +R+
Sbjct: 531 YPIRPDLPIMEDLTFTVEPGEVVALVGPSGGGKSSCIAMLEHFYEPTSGEVLIDGVPVRE 590
Query: 497 FNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLAN-F 555
++ + + +V QEP+L++ ++ +NI Y + + D+ + + AN F+ N
Sbjct: 591 YDHKFLHTKVALVGQEPVLYARSVTENIGYGLDK---YDDDMVQNSAKLANAHTFIMNDT 647
Query: 556 PDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQR 615
DG T VG +G+Q+SGGQKQRIA+ARA + P +L+LDEATSALD++SE V +++ +
Sbjct: 648 TDGYNTNVGEKGSQMSGGQKQRIAIARALVRQPVVLLLDEATSALDAESEHTVQEAI-SK 706
Query: 616 SARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ +GKT I IAHR+ST++++ +++V+N+ G V + G+ L+
Sbjct: 707 NLKGKTVILIAHRLSTVENADKIVVINK-GKVEQLGNHKTLM 747
>CE24404 [U] KOG0058 Peptide exporter ABC superfamily
Length = 807
Score = 263 bits (671), Expect = 9e-70
Identities = 164/517 (31%), Positives = 267/517 (50%), Gaps = 8/517 (1%)
Query: 155 LGGVFVVGALANVGRIVILKVTGERLVAR-LRTRTMKAALEQDATFLDHNRVGDLISRLS 213
L V A N R + ++ ERL AR +R +A L QD +F D N+ G L+SR++
Sbjct: 277 LAAVQFTEATVNTVRYICMQYA-ERLTARNIRVSLFRAILHQDISFFDDNKTGQLMSRIT 335
Query: 214 SDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRI 273
D+ +S S+ + F +M + SW+L + P + + YG +
Sbjct: 336 KDSESISNSLPVYIETTVNNSFMLFGSAPIMFYYSWQLAISTFVTFPIILLTTKFYGLIV 395
Query: 274 RNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSG 333
LS + + + EE LSA +T++++ EK E RY + F + K +
Sbjct: 396 EKLSEKENDATAVSNETVEEVLSAIRTVRSFAAEKIENMRYTRDTDAWFKISTKTVVFGT 455
Query: 334 AFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELM 393
F + N+ + + L G + G M L +++ Y ++M
Sbjct: 456 FFNYFWATMWNIEDVIIYLYGGYLTLNGRMEPDALLTYIFYHWRLHSALNAFSSLFSDVM 515
Query: 394 KGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTV 453
K G++ +V + +R+P + G + + I F V+F+YPTR ++ +N ++
Sbjct: 516 KTIGSSRKVIHIMNRQPELDYEFGTETPEIVGNII-FEDVEFAYPTRKNANVLNKINLSI 574
Query: 454 RPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEP 513
PG+ + +VGPSG GKST+ SL+ ++Y SG I + I++ + Y + +V QEP
Sbjct: 575 DPGKTIALVGPSGNGKSTLVSLIQQFYTPQSGRILIDGTPIQNIDHLHYHTNIALVAQEP 634
Query: 514 MLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGG 573
LFSGT+ +NI Y + D R++ AN +F++ G T G +G Q+SGG
Sbjct: 635 TLFSGTVRENILYGLENGTDEDMMRVAE---MANVHEFVSKMEKGYDTKCGEKGVQMSGG 691
Query: 574 QKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQ 633
QKQRIA+ARA + DP +LILDEATSALDS+SE +V ++L R AR +T + IAHR+ST++
Sbjct: 692 QKQRIAIARALIRDPRVLILDEATSALDSESEAMVQEAL-NRCARERTVLVIAHRLSTVR 750
Query: 634 HSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
+ R+ V+ + G V E G+ ++L+ + KL+SK
Sbjct: 751 SADRIAVIEK-GNVTEMGNHEELMKNTEGLYYKLVSK 786
>At3g28390 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1225
Score = 261 bits (668), Expect = 2e-69
Identities = 173/507 (34%), Positives = 276/507 (54%), Gaps = 31/507 (6%)
Query: 176 TGERLVARLRTRTMKAALEQDATFLDHN--RVGDLISRLSSDAGIVSKSVTQNLSD---G 230
TGER A++R + +KA L QD + D + D+I+ +SSD+ ++ +++ L +
Sbjct: 93 TGERQAAKMREKYLKAVLRQDVGYFDLHVTSTSDVITSVSSDSLVIQDFLSEKLPNFLMN 152
Query: 231 TRAVIQGF-VGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTK 289
T A + + VGF ++ W+LT V L + L+YG+ + +S +++ E
Sbjct: 153 TSAFVASYIVGFLLL----WRLTIVGFPFIILLLIPGLMYGRALIRISMKIREEYNEAGS 208
Query: 290 VSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLA 349
++E+ +S+ +T+ A+ EKK I +++ ++ +GL++ L G G G A+
Sbjct: 209 IAEQVISSVRTVYAFGSEKKMIEKFSTALQGSVKLGLRQGLAKGIAIGSNGIT--YAIWG 266
Query: 350 LLLT-GTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDR 408
L G+ M+ G +SS ++ + R+ ++ +R
Sbjct: 267 FLTWYGSRMVMNHGSKGGTVSSVIVCVTFGGTSLGQSLSNLKYFSEAFVVGERIMKVINR 326
Query: 409 KPLIHPTIGKDPVTLENK-------SIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCI 461
P G D LE + + FNHVKF+YP+RP+ IF+DL V G+ V +
Sbjct: 327 VP------GIDSDNLEGQILEKTRGEVEFNHVKFTYPSRPETPIFDDLCLRVPSGKTVAL 380
Query: 462 VGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTIL 521
VG SG GKSTV SLL R+YD +GEI + I ++ R +G+V QEP+LF+ +I
Sbjct: 381 VGGSGSGKSTVISLLQRFYDPIAGEILIDGLPINKLQVKWLRSQMGLVSQEPVLFATSIK 440
Query: 522 DNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALA 581
+NI + +++ ++A +N F++ FP+ QT VG RG QLSGGQKQRIA+A
Sbjct: 441 ENILFGKEDASMDEVVEAAKA---SNAHSFISQFPNSYQTQVGERGVQLSGGQKQRIAIA 497
Query: 582 RAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVL 641
RA + P IL+LDEATSALDS+SE VV ++L S G+TTI IAHR+STI+++ VI +
Sbjct: 498 RAIIKSPIILLLDEATSALDSESERVVQEALDNASI-GRTTIVIAHRLSTIRNAD-VICV 555
Query: 642 NRHGTVAETGSFDKLIAIPDSSLNKLL 668
+G + ETGS ++L+ D L+
Sbjct: 556 VHNGRIIETGSHEELLEKLDGQYTSLV 582
Score = 252 bits (644), Expect = 1e-66
Identities = 172/514 (33%), Positives = 261/514 (50%), Gaps = 7/514 (1%)
Query: 149 TQFYTALG-GVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLD--HNRV 205
T+ Y L G+ + L+N+ + GE L R+R R + L + + D N
Sbjct: 697 TRIYVLLFVGLALFTFLSNISQHYGFAYMGEYLTKRIRERMLGKILTFEVNWFDKDENSS 756
Query: 206 GDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVM 265
G + SRL+ DA +V V +S + + + + ISW+ + VMM + P + V
Sbjct: 757 GAICSRLAKDANMVRSLVGDRMSLLVQTISAVSITCAIGLVISWRFSIVMMSVQPVIVVC 816
Query: 266 ALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVG 325
++++SR E +K++ E +S +TI A+ +++ I+
Sbjct: 817 FYTQRVLLKSMSRNAIKGQDESSKLAAEAVSNIRTITAFSSQERIINLLKMVQEGPRKDS 876
Query: 326 LKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXX 385
+++ +G G + + G +I G M + +
Sbjct: 877 ARQSWLAGIMLGTSQSLITCVSALNFWYGGKLIADGKMMSKEFLEIFLIFASTGRVIAEA 936
Query: 386 XXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKS-IHFNHVKFSYPTRPQHH 444
+L+KG+ A A VF + DR I P V + K I F++V F+YPTRP
Sbjct: 937 GTMTKDLVKGSDAVASVFAVLDRNTTIEPENPDGYVPKKVKGQISFSNVDFAYPTRPDVI 996
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
IF++ + + G+ IVGPSG GKST+ SL+ R+YD G +K+ +IR +LR R+
Sbjct: 997 IFQNFSIDIEDGKSTAIVGPSGSGKSTIISLIERFYDPLKGIVKIDGRDIRSCHLRSLRQ 1056
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
+ +V QEP LF+GTI +NI Y + DE+ I A AN F+ + +G T G
Sbjct: 1057 HIALVSQEPTLFAGTIRENIMYGGASNKI-DESEIIEAAKAANAHDFITSLSNGYDTCCG 1115
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
RG QLSGGQKQRIA+ARA L +PS+L+LDEATSALDSQSE VV +L +R G+T++
Sbjct: 1116 DRGVQLSGGQKQRIAIARAVLKNPSVLLLDEATSALDSQSESVVQDAL-ERLMVGRTSVV 1174
Query: 625 IAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
IAHR+STIQ + VL +G V E G+ L+A
Sbjct: 1175 IAHRLSTIQKCDTIAVL-ENGAVVECGNHSSLLA 1207
>At3g28360 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1158
Score = 261 bits (667), Expect = 3e-69
Identities = 167/489 (34%), Positives = 269/489 (54%), Gaps = 13/489 (2%)
Query: 176 TGERLVARLRTRTMKAALEQDATFLDHN--RVGDLISRLSSDAGIVSKSVTQNLSDGTRA 233
TGER A++R R ++A L QD + D + D+I+ +SSD+ ++ +++ L +
Sbjct: 22 TGERQAAKMRERYLRAVLRQDVGYFDLHVTSTSDIITSVSSDSLVIQDFLSEKLPNILMN 81
Query: 234 VIQGFVGFGMMSF-ISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSE 292
FVG ++ F + W+LT V L + L+YG+ + +SR+++ E ++E
Sbjct: 82 A-SAFVGSYIVGFMLLWRLTIVGFPFIILLLIPGLMYGRALIGISRKIREEYNEAGSIAE 140
Query: 293 EQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLL 352
+ +S+ +T+ A+ EKK I +++D ++ +GL++ L G G G V A+ L
Sbjct: 141 QAISSVRTVYAFVSEKKMIEKFSDALQGSVKLGLRQGLAKGIAIGSNGIV--YAIWGFLT 198
Query: 353 T-GTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPL 411
G+ M+ G +S+ + + A R+ ++ R P
Sbjct: 199 WYGSRMVMNYGYKGGTVSTVTVCVTFGGTALGQALSNLKYFSEAFVAGERIQKMIKRVPD 258
Query: 412 IHP-TIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKS 470
I + + + FN+VK YP+RP+ IF+DL + G+ V +VG SG GKS
Sbjct: 259 IDSDNLNGHILETIRGEVEFNNVKCKYPSRPETLIFDDLCLKIPSGKTVALVGGSGSGKS 318
Query: 471 TVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQ 530
TV SLL R+YD G+I + + +I + ++ R +G+V QEP LF+ +I +NI +
Sbjct: 319 TVISLLQRFYDPNEGDILIDSVSINNMQVKWLRSQMGMVSQEPSLFATSIKENILFGKED 378
Query: 531 ELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSI 590
++ ++A +N F++ FP G QT VG RG +SGGQKQRIA+ARA + P I
Sbjct: 379 ASFDEVVEAAKA---SNAHNFISQFPHGYQTQVGERGVHMSGGQKQRIAIARALIKSPII 435
Query: 591 LILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAET 650
L+LDEATSALD +SE VV ++L S G+TTI IAHR+STI+++ + VL+ +G + ET
Sbjct: 436 LLLDEATSALDLESERVVQEALDNASV-GRTTIVIAHRLSTIRNADIICVLH-NGCIVET 493
Query: 651 GSFDKLIAI 659
GS DKL+ I
Sbjct: 494 GSHDKLMEI 502
Score = 247 bits (631), Expect = 4e-65
Identities = 171/524 (32%), Positives = 263/524 (49%), Gaps = 26/524 (4%)
Query: 142 MIFGLTSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLD 201
+ FGL F+T++ + + GE L R+R + + L + + D
Sbjct: 634 LFFGLALFTFFTSISQQYSFSYM------------GEYLTKRIREQMLSKILTFEVNWFD 681
Query: 202 H--NRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLA 259
N G + SRL+ DA +V V + +S + + V + I+W+ T VM+ +
Sbjct: 682 EEENSSGAICSRLAKDANVVRSLVGERMSLLVQTISTVMVACTIGLVIAWRFTIVMISVQ 741
Query: 260 PPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEK---KEIHRYAD 316
P + V + ++N+S++ + E +K++ E +S +TI + ++ K + R +
Sbjct: 742 PVIIVCYYIQRVLLKNMSKKAIIAQDESSKLAAEAVSNIRTITTFSSQERIMKLLERVQE 801
Query: 317 EVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAV 376
R+ +++ +G G T + G +I G M +
Sbjct: 802 GPRRE---SARQSWLAGIMLGTTQSLITCTSALNFWYGGKLIADGKMVSKAFFELFLIFK 858
Query: 377 XXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLEN--KSIHFNHVK 434
+L KG+ + VF + DR+ I P D LE I F +V
Sbjct: 859 TTGRAIAEAGTMTTDLAKGSNSVDSVFTVLDRRTTIEPE-NPDGYILEKIKGQITFLNVD 917
Query: 435 FSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNI 494
F+YPTRP IF + + + G+ IVGPS GKSTV L+ R+YD G +K+ +I
Sbjct: 918 FAYPTRPNMVIFNNFSIEIHEGKSTAIVGPSRSGKSTVIGLIERFYDPLQGIVKIDGRDI 977
Query: 495 RDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLAN 554
R ++LR R+ + +V QEP LF+GTI +NI Y + DE+ I A AN +F+ +
Sbjct: 978 RSYHLRSLRQHMSLVSQEPTLFAGTIRENIMYGRASNKI-DESEIIEAGKTANAHEFITS 1036
Query: 555 FPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQ 614
DG T G RG QLSGGQKQRIA+AR L +PSIL+LDEATSALDSQSE VV +L+
Sbjct: 1037 LSDGYDTYCGDRGVQLSGGQKQRIAIARTILKNPSILLLDEATSALDSQSERVVQDALEH 1096
Query: 615 RSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
GKT++ IAHR+STIQ+ + VL++ G V E+G+ L+A
Sbjct: 1097 VMV-GKTSVVIAHRLSTIQNCDTIAVLDK-GKVVESGTHASLLA 1138
>CE03260 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1318
Score = 260 bits (665), Expect = 4e-69
Identities = 163/535 (30%), Positives = 280/535 (51%), Gaps = 30/535 (5%)
Query: 142 MIFGLTSTQFYTA-------LGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALE 194
+I TS FY + GG+ ++ + N + + + R+ ++++ +++ L
Sbjct: 122 LIHNATSDDFYDSAMTNVWLFGGIGIIVLIVNFVQYMCFQYCCIRITSKMKQHYIQSILR 181
Query: 195 QDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCV 254
Q+A + D N G L ++L + +++ + L R ++ G + F W+L +
Sbjct: 182 QNAGWFDKNHSGTLTTKLHDNMERINEGIGDKLGVLIRGMVMFVAGIVISFFYEWRLALM 241
Query: 255 MMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRY 314
MM + P V + + + + + + VG+ ++EE L +T+QA+ G+++ + +Y
Sbjct: 242 MMGIGPLCCVCMSLMSRSMSSFTSKELAGVGKAGSIAEESLMGVRTVQAFNGQEEMVEKY 301
Query: 315 ADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLAL-------LLTGTSMIKTGLM-TVG 366
E+ K +++ L G F G + LL L + G +++ ++ T G
Sbjct: 302 TVELGKGKSFAIQKGLWGGVF-------GGIFLLFLFSYFGGGIYYGGQLLRWKIIETPG 354
Query: 367 DLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLI--HPTIGKDPVTLE 424
D+ ++ + L+ AAA ++E+ DR P I + T G+ +
Sbjct: 355 DVFIVVISMLIGAYFLGLISPHLMVLLNARVAAATIYEIIDRTPDIDVYSTEGQKMTNVV 414
Query: 425 NKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGS 484
K + F V F YPTR + + LN TV+PG V +VG SG GKST LL R Y+
Sbjct: 415 GKVV-FEEVHFRYPTRKKVKVLNGLNLTVKPGTSVALVGHSGCGKSTSVGLLTRLYEPEG 473
Query: 485 GEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIG 544
G++ + ++R N+ R+ +G+VQQEP+LF+ TI +N+ P D R+ +
Sbjct: 474 GKVMIDGQDVRSLNIDWLRKTVGIVQQEPILFNDTIHNNLLIGNPSATREDMIRVCK--- 530
Query: 545 QANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQS 604
AN F+ P+G +T +G QLSGGQKQR+A+AR + DP +L+LDEATSALD+QS
Sbjct: 531 MANAHDFIQKMPNGYETMIGDGSVQLSGGQKQRVAIARTLIRDPKVLLLDEATSALDAQS 590
Query: 605 EEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAI 659
E VV QS +A+G+TTI IAHR+STI+ + + IV +G + E+G+ ++L+A+
Sbjct: 591 ESVV-QSALNNAAKGRTTIMIAHRLSTIREADK-IVFFENGVIVESGNHEELVAL 643
Score = 241 bits (614), Expect = 4e-63
Identities = 169/523 (32%), Positives = 271/523 (51%), Gaps = 38/523 (7%)
Query: 152 YTALG-GVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDH--NRVGDL 208
Y ALG VF+ ++ + + E L + R ++ K L QDA+F D+ + G L
Sbjct: 804 YVALGLFVFITQVISGT----LFTIVAENLGLKFRVQSFKNLLYQDASFFDNPAHAPGKL 859
Query: 209 ISRLSSDA----GIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGV 264
I+RL+SDA +V + Q + T I G+ I+ T +++L A +
Sbjct: 860 ITRLASDAPNVKAVVDTRMLQVIYSITSITINLITGYIFCWRIAIAGTIMIVLFATMMIS 919
Query: 265 MALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYAD-------- 316
MA K R +Q++ E K++ E + + KTIQ ++ + Y D
Sbjct: 920 MAY---KIARENLKQIRKD--EAGKIAIEIIESVKTIQLLTSTQRFLTHYKDAQLVQHKS 974
Query: 317 EVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAV 376
E+RK + + A++ + A+ GT ++ G++ + +
Sbjct: 975 EMRKSYIQSVNNAISQTFMY--------FAMFVCYGVGTPLMYHGIVEAEPTFRAINCMM 1026
Query: 377 XXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFS 436
E +K AA +F+L RK + + + ++ F VKFS
Sbjct: 1027 MGSVAVMHSSHNFPEFVKAKTAAGMLFKLIYRKSKTGDVMEGNNTEIRG-NVLFESVKFS 1085
Query: 437 YPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRD 496
YP RP + DL+F+ G+ V +VGPSG GKST ++L R+YD+ G +++ NI+
Sbjct: 1086 YPQRPMQPVMTDLHFSAHSGQTVALVGPSGTGKSTCIAMLERFYDVSGGALRIDGQNIKS 1145
Query: 497 FNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFP 556
+L R + +V QEP LF+GTI +N+ + + V ++ +A+ AN ++FLAN P
Sbjct: 1146 LSLHHLRTQMALVGQEPRLFAGTIKENVCFGLKDVSVE---KVHQALELANASRFLANLP 1202
Query: 557 DGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRS 616
G+ T VG +G QLSGGQKQRIA+ARA + DP IL+LDEATSALDS+SE V ++L R+
Sbjct: 1203 AGIDTEVGEKGGQLSGGQKQRIAIARALVRDPKILLLDEATSALDSESERAVQEAL-DRA 1261
Query: 617 ARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAI 659
G+T I+IAHR+S+IQ+S ++ ++ HG V E G+ L+++
Sbjct: 1262 REGRTCITIAHRLSSIQNSDLIVYID-HGMVQEAGNHAHLMSL 1303
>At3g28380 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1240
Score = 260 bits (664), Expect = 6e-69
Identities = 172/499 (34%), Positives = 273/499 (54%), Gaps = 13/499 (2%)
Query: 176 TGERLVARLRTRTMKAALEQDATFLDHN--RVGDLISRLSSDAGIVSKSVTQNLSDGTRA 233
TGER AR+R + ++A L QD + D + D+I+ +SSD+ ++ +++ L +
Sbjct: 105 TGERQAARMREKYLRAVLRQDVGYFDLHVTSTSDVITSISSDSLVIQDFLSEKLPNFLMN 164
Query: 234 VIQGFVGFGMMSFI-SWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSE 292
FV ++SFI W+LT V L V L+YG+ + ++SR++ E ++E
Sbjct: 165 A-SAFVASYIVSFILMWRLTIVGFPFIILLLVPGLMYGRALVSISRKIHEQYNEAGSIAE 223
Query: 293 EQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLL 352
+ +S+ +T+ A+ E K I +++ +R +GL++ L G G G A+ A L
Sbjct: 224 QAISSVRTVYAFGSENKMIGKFSTALRGSVKLGLRQGLAKGITIGSNGVTH--AIWAFLT 281
Query: 353 TGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAA-ARVFELNDRKPL 411
S + + G ++ + + A A R+ E+ R P
Sbjct: 282 WYGSRLVMNHGSKGGTVFVVISCITYGGVSLGQSLSNLKYFSEAFVAWERILEVIKRVPD 341
Query: 412 IHPTIGKDPVTLENKS-IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKS 470
I + + K + FNHVKF+Y +RP+ IF+DL + G+ V +VG SG GKS
Sbjct: 342 IDSNKKEGQILERMKGEVEFNHVKFTYLSRPETTIFDDLCLKIPAGKTVALVGGSGSGKS 401
Query: 471 TVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQ 530
TV SLL R+YD +GEI + +I + R +G+V QEP+LF+ +I +NI +
Sbjct: 402 TVISLLQRFYDPIAGEILIDGVSIDKLQVNWLRSQMGLVSQEPVLFATSITENILFGKED 461
Query: 531 ELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSI 590
+++ ++A +N F++ FP G +T VG RG Q+SGGQKQRIA+ARA + P I
Sbjct: 462 ASLDEVVEAAKA---SNAHTFISQFPLGYKTQVGERGVQMSGGQKQRIAIARAIIKSPKI 518
Query: 591 LILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAET 650
L+LDEATSALDS+SE VV +SL S G+TTI IAHR+STI+++ + V++ +G + ET
Sbjct: 519 LLLDEATSALDSESERVVQESLDNASI-GRTTIVIAHRLSTIRNADVICVIH-NGQIVET 576
Query: 651 GSFDKLIAIPDSSLNKLLS 669
GS ++L+ D L+S
Sbjct: 577 GSHEELLKRIDGQYTSLVS 595
Score = 246 bits (629), Expect = 7e-65
Identities = 169/526 (32%), Positives = 264/526 (50%), Gaps = 14/526 (2%)
Query: 143 IFGLTS-------TQFYTALG-GVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALE 194
+F LTS T+ Y L G+ + L N+ + GE L R+R + + L
Sbjct: 699 VFFLTSHDQIKEKTRIYVLLFVGLAIFSFLVNISQHYGFAYMGEYLTKRIREQMLSKILT 758
Query: 195 QDATF--LDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLT 252
+ + +D N G + SRL+ DA +V V +S + + + + I+W+L
Sbjct: 759 FEVNWFDIDDNSSGAICSRLAKDANVVRSMVGDRMSLLVQTISAVIIACIIGLVIAWRLA 818
Query: 253 CVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIH 312
VM+ + P + V +++LS + + E +K++ E +S +TI A+ +++ I
Sbjct: 819 IVMISVQPLIVVCFYTQRVLLKSLSEKASKAQDESSKLAAEAVSNIRTITAFSSQERIIK 878
Query: 313 RYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFM 372
+ + +G G + + G +I G +
Sbjct: 879 LLKKVQEGPRRESVHRSWLAGIVLGTSRSLITCTSALNFWYGGRLIADGKIVSKAFFEIF 938
Query: 373 MYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKS-IHFN 431
+ V +L +G A VF + DR I P V + K I F
Sbjct: 939 LIFVTTGRVIADAGTMTTDLARGLDAVGSVFAVLDRCTTIEPKNPDGYVAEKIKGQITFL 998
Query: 432 HVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGN 491
+V F+YPTRP IFE+ + + G+ IVG SG GKST+ L+ R+YD G +K+
Sbjct: 999 NVDFAYPTRPDVVIFENFSIEIDEGKSTAIVGTSGSGKSTIIGLIERFYDPLKGTVKIDG 1058
Query: 492 DNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKF 551
+IR ++LR R+ + +V QEPMLF+GTI +NI Y + + DE+ I A AN F
Sbjct: 1059 RDIRSYHLRSLRKYISLVSQEPMLFAGTIRENIMYGGTSDKI-DESEIIEAAKAANAHDF 1117
Query: 552 LANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQS 611
+ + +G T G +G QLSGGQKQRIA+ARA L +PS+L+LDEATSALDS+SE VV +
Sbjct: 1118 ITSLSNGYDTNCGDKGVQLSGGQKQRIAIARAVLKNPSVLLLDEATSALDSKSERVVQDA 1177
Query: 612 LQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
L +R G+T+I IAHR+STIQ+ ++VL + G + E+G+ L+
Sbjct: 1178 L-ERVMVGRTSIMIAHRLSTIQNCDMIVVLGK-GKIVESGTHSSLL 1221
>At3g28345 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1240
Score = 259 bits (661), Expect = 1e-68
Identities = 170/508 (33%), Positives = 264/508 (51%), Gaps = 12/508 (2%)
Query: 157 GVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSS 214
G+ V+ L N+ + GE L R+R R + L + + D N G + SRL+
Sbjct: 721 GLAVLSFLINISQHYNFAYMGEYLTKRIRERMLSKVLTFEVGWFDRDENSSGAICSRLAK 780
Query: 215 DAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIR 274
DA +V V ++ + V + F M I+W+L VM+ + P + V ++
Sbjct: 781 DANVVRSLVGDRMALVVQTVSAVTIAFTMGLVIAWRLALVMIAVQPVIIVCFYTRRVLLK 840
Query: 275 NLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGA 334
++S++ + E +K++ E +S +TI A+ +++ + ++++ +G
Sbjct: 841 SMSKKAIKAQDESSKLAAEAVSNVRTITAFSSQERIMKMLEKAQESPRRESIRQSWFAGF 900
Query: 335 FFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMK 394
++ + + G +I+ G +T L M V +L K
Sbjct: 901 GLAMSQSLTSCTWALDFWYGGRLIQDGYITAKALFETFMILVSTGRVIADAGSMTTDLAK 960
Query: 395 GAGAAARVFELNDRKPLIHPTIGKDPVTLENKSI----HFNHVKFSYPTRPQHHIFEDLN 450
G+ A VF + DR I P +DP E + I F V FSYPTRP IF++ +
Sbjct: 961 GSDAVGSVFAVLDRYTSIDP---EDPDGYETERITGQVEFLDVDFSYPTRPDVIIFKNFS 1017
Query: 451 FTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQ 510
+ G+ IVGPSG GKST+ L+ R+YD G +K+ +IR ++LR RR + +V
Sbjct: 1018 IKIEEGKSTAIVGPSGSGKSTIIGLIERFYDPLKGIVKIDGRDIRSYHLRSLRRHIALVS 1077
Query: 511 QEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQL 570
QEP LF+GTI +NI Y + + DE I A AN F+ + +G T G RG QL
Sbjct: 1078 QEPTLFAGTIRENIIYGGVSDKI-DEAEIIEAAKAANAHDFITSLTEGYDTYCGDRGVQL 1136
Query: 571 SGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVS 630
SGGQKQRIA+ARA L +PS+L+LDEATSALDSQSE VV +L +R G+T++ IAHR+S
Sbjct: 1137 SGGQKQRIAIARAVLKNPSVLLLDEATSALDSQSERVVQDAL-ERVMVGRTSVVIAHRLS 1195
Query: 631 TIQHSSRVIVLNRHGTVAETGSFDKLIA 658
TIQ+ + VL++ G + E G+ L++
Sbjct: 1196 TIQNCDAIAVLDK-GKLVERGTHSSLLS 1222
Score = 258 bits (660), Expect = 2e-68
Identities = 170/499 (34%), Positives = 275/499 (55%), Gaps = 15/499 (3%)
Query: 176 TGERLVARLRTRTMKAALEQDATFLDHN--RVGDLISRLSSDAGIVSKSVTQNLSDGTRA 233
TGER AR+R + ++A L QD + D + D+I+ +SSD+ ++ +++ L + +
Sbjct: 105 TGERQTARMREKYLRAVLRQDVGYFDLHVTSTSDVITSVSSDSFVIQDVLSEKLPNFLMS 164
Query: 234 VIQGFVGFGMMSFIS-WKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSE 292
FVG ++ FI W+L V + L + L+YG+ + ++SR+++ E V+E
Sbjct: 165 A-STFVGSYIVGFILLWRLAIVGLPFIVLLVIPGLMYGRALISISRKIREEYNEAGFVAE 223
Query: 293 EQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLL 352
+ +S+ +T+ A+ GE+K I +++ ++ +G+K+ L G G G A+ +
Sbjct: 224 QAISSVRTVYAFSGERKTISKFSTALQGSVKLGIKQGLAKGITIGSNGIT--FAMWGFMS 281
Query: 353 T-GTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPL 411
G+ M+ G + + + A R+ E+ +R P
Sbjct: 282 WYGSRMVMYHGAQGGTVFAVAAAIAIGGVSLGGGLSNLKYFFEAASVGERIMEVINRVPK 341
Query: 412 IHPTIGKDPVTLEN--KSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGK 469
I D LE + F +VKF YP+R + IF+D V G+ V +VG SG GK
Sbjct: 342 IDSD-NPDGHKLEKIRGEVEFKNVKFVYPSRLETSIFDDFCLRVPSGKTVALVGGSGSGK 400
Query: 470 STVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVP 529
STV SLL R+YD +GEI + +I ++ R +G+V QEP LF+ TI +NI +
Sbjct: 401 STVISLLQRFYDPLAGEILIDGVSIDKLQVKWLRSQMGLVSQEPALFATTIKENILFGKE 460
Query: 530 QELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPS 589
++D ++A +N F++ P+G +T VG RG Q+SGGQKQRIA+ARA + P+
Sbjct: 461 DASMDDVVEAAKA---SNAHNFISQLPNGYETQVGERGVQMSGGQKQRIAIARAIIKSPT 517
Query: 590 ILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAE 649
IL+LDEATSALDS+SE VV ++L+ S G+TTI IAHR+STI+++ VI + ++G + E
Sbjct: 518 ILLLDEATSALDSESERVVQEALENASI-GRTTILIAHRLSTIRNAD-VISVVKNGHIVE 575
Query: 650 TGSFDKLIAIPDSSLNKLL 668
TGS D+L+ D + L+
Sbjct: 576 TGSHDELMENIDGQYSTLV 594
>CE23998 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1225
Score = 257 bits (657), Expect = 4e-68
Identities = 165/516 (31%), Positives = 268/516 (50%), Gaps = 47/516 (9%)
Query: 145 GLTSTQFYTALGGV--FVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDH 202
G+ F+ L G F+ +L + I+K G+ R+R + + L++DA + D
Sbjct: 98 GMNQVVFHFFLCGCAYFIFASLQHA----IMKYVGDNTTYRVRKQYISRLLKKDAQYFDS 153
Query: 203 NRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPL 262
G L + L+ + + + ++ V +G + + W+L + + +
Sbjct: 154 VSTGHLSTVLNDNLERFREVFNEKIALIIAFVTDFTLGTALAFYTDWRLASYGIFFSLGI 213
Query: 263 GVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVF 322
+ + + + T ++ + L A KT+ + G+K EI RY +E++
Sbjct: 214 AFSGFINSAGVMKTTGKQNTHYANAGSIAFQTLGAYKTVCSLNGQKTEIERYTEELKAGE 273
Query: 323 HVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXX 382
G++ AL GVT F N +L G +MI +G + +
Sbjct: 274 KYGIRRALMYSISRGVTYFFCNSLNTVVLYVGATMIYSGTLETAVV-------------- 319
Query: 383 XXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQ 442
+ D + D N +I F +VKFSYPTRP
Sbjct: 320 ----------------------VRDDNVIEKDETDYDVEVEVNGNISFKNVKFSYPTRPD 357
Query: 443 HHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKY 502
+ + ++F V+ GE + +VG SG GKSTV LLL YY+I SG I + ++ D N+++
Sbjct: 358 AQVLKGISFDVQNGECIALVGASGSGKSTVVQLLLHYYNIDSGNIFIDGMDLNDMNIKRL 417
Query: 503 RRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTT 562
RR++GVV QEP+LF+ TI +NI + P + + I A+ +AN F+ +FP G++T
Sbjct: 418 RRVIGVVSQEPVLFNTTIEENIRFGNPNVSLPE---IYGALRKANAYDFVCSFPKGIKTI 474
Query: 563 VGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTT 622
VG RGTQLSGGQKQRIA+AR + +P IL+LDEATSALD++SE+VV ++L+ S +G+TT
Sbjct: 475 VGERGTQLSGGQKQRIAIARTLVRNPKILLLDEATSALDNESEQVVQKALENAS-QGRTT 533
Query: 623 ISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
I +AHR+STI+++S++IV+ + G + E G+ D+LIA
Sbjct: 534 IVVAHRLSTIRNASKIIVMQK-GEIVEVGNHDELIA 568
Score = 222 bits (566), Expect = 1e-57
Identities = 149/482 (30%), Positives = 237/482 (48%), Gaps = 6/482 (1%)
Query: 178 ERLVARLRTRTMKAALEQDATFLD--HNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVI 235
E+L RLR ++ L F D ++ L +RL++D+ V +V L V+
Sbjct: 726 EQLSTRLRIKSFSHMLSLPCAFYDDPNHSATRLSNRLNTDSSNVKAAVDDRLGCVIMTVV 785
Query: 236 QGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQL 295
+ S WK+T +++ P L + Y ++ + + + E L
Sbjct: 786 AISIAITTASLYCWKMTLEVLMFFPLLYLAEYCYEAATETAIQEDTIAFENSNRTAIEAL 845
Query: 296 SATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGT 355
+T++A E K + ++ ++K+ K A+ GA G++ GT
Sbjct: 846 ENVRTVRALNLEDKIMSLISEHLQKIHKSYFKRAIIQGAANGLSLSCFLFVYSVSFKFGT 905
Query: 356 SMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPT 415
+ + D +M + K AA +F L + +
Sbjct: 906 YLALRKEVAPMDTYLVLMTLSMTANMAGSAAAYLPDYKKAVHAAGLIFHLFTYPATMPFS 965
Query: 416 IGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASL 475
+E I +V+F Y RP I +N V PG+ + +VGPSG GKST+ SL
Sbjct: 966 SSDGKKNIEKGEIIGENVQFHYDQRPDRMILNGVNLKVDPGKTLALVGPSGCGKSTIISL 1025
Query: 476 LLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVND 535
L R+Y GE+K+ ++N+ D NL R L +V QEP LF+ +I +N+ Y + + +
Sbjct: 1026 LERFYHAVDGEVKIDSENVEDINLNHLRSNLALVSQEPTLFNCSIRENLLYGLTRSV--P 1083
Query: 536 ETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDE 595
+ + +A+ AN F+ FP GL T VG RG QLSGGQKQRIA+ARA L +P +L+LDE
Sbjct: 1084 QLELEKALQTANAFNFVFQFPQGLDTLVGERGAQLSGGQKQRIAIARAILRNPKVLLLDE 1143
Query: 596 ATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDK 655
ATSALDS SE+VV +L S R +T+ +AHR+ST+ ++ + VL ++G VAE G+ ++
Sbjct: 1144 ATSALDSDSEKVVQNALDTASER-LSTVVVAHRLSTVVNADSIAVL-KNGKVAEQGTHEE 1201
Query: 656 LI 657
L+
Sbjct: 1202 LL 1203
>CE14926 [U] KOG0058 Peptide exporter ABC superfamily
Length = 633
Score = 256 bits (654), Expect = 8e-68
Identities = 159/494 (32%), Positives = 256/494 (51%), Gaps = 7/494 (1%)
Query: 178 ERLVAR-LRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQ 236
E+L AR +R + ++ L Q+ +F D N+ G L+SR++ D+ +S ++ ++ +
Sbjct: 123 EKLTARNIRIQLFRSILHQEISFFDENKTGQLVSRITHDSESISNTLPVHIETLVNNLFM 182
Query: 237 GFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLS 296
F +M SW+LT + P +M YG + LS + + + EE LS
Sbjct: 183 FFGSIPIMFCYSWQLTLTSFIEFPITLLMTRYYGLAVEKLSEKENDATAASNETVEEVLS 242
Query: 297 ATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTS 356
A +T++++ E E RY F + K + + + L G
Sbjct: 243 AIRTVRSFAAENFEQKRYTKNTEDWFKISTKTVTLGTIYNYFWALMLRSQDVIRYLYGGY 302
Query: 357 MIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTI 416
+ G M L +F+ Y +MK G + +V L +RKP +
Sbjct: 303 LALNGRMAPEALLTFIFYHWRLHTAINAFSSLFSGVMKTIGLSRKVIHLINRKPQLDYDF 362
Query: 417 GKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL 476
G + ++ K I F V+F+YPTR ++ +N ++ G+ V +VGPSG GKST+ SL+
Sbjct: 363 GTETPEIQGK-IEFEVVEFAYPTRKTVNVINGINLSIESGKTVALVGPSGNGKSTLVSLI 421
Query: 477 LRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDE 536
++Y SG I I++ N + Y + +V QEP LFSGTI +NI + + E
Sbjct: 422 QQFYTPQSGRILTDGIPIQNINHQHYHSNIALVAQEPTLFSGTIRENILFGIEN---GTE 478
Query: 537 TRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEA 596
+ +A AN +F++ DG T G +G Q+SGGQKQRIA+ARA + +P +LILDEA
Sbjct: 479 EAMLKAAEMANVHEFVSKMDDGYDTKCGEKGVQMSGGQKQRIAIARALIRNPRVLILDEA 538
Query: 597 TSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
TSALDS+SE +V ++L + A+ +T I IAHR+ST++ + ++ V+ +G+V E G D+L
Sbjct: 539 TSALDSESEGMVQEAL-NKCAKERTVIVIAHRLSTVRKAQKIAVI-ENGSVKEMGCHDEL 596
Query: 657 IAIPDSSLNKLLSK 670
+ D KL+SK
Sbjct: 597 MENQDGLYYKLVSK 610
>At5g46540 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1248
Score = 255 bits (652), Expect = 1e-67
Identities = 166/502 (33%), Positives = 262/502 (52%), Gaps = 9/502 (1%)
Query: 172 ILKVTGERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSSDAGIVSKSVTQNLSD 229
+ + G +L+ R+R+ + L QD ++ D N G + +RLS+DA V KS+ ++
Sbjct: 746 LFAIAGAKLIKRIRSLSFDRVLHQDISWFDDTKNSSGVIGARLSTDASTV-KSIVGDVLG 804
Query: 230 GTRAVIQGFVGFGMMSFIS-WKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELT 288
+ +G +++F + W L + +L+AP + K I + + E +
Sbjct: 805 LIMQNMATIIGAFIIAFTANWLLALMALLVAPVMFFQGYYQIKFITGFGAKARGKYEEAS 864
Query: 289 KVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALL 348
+V+ + +S+ +T+ ++C E K + Y ++ + G K L SG +G + V
Sbjct: 865 QVASDAVSSIRTVASFCAEDKVMDLYQEKCDEPKQQGFKLGLVSGLCYGGSYLALYVIES 924
Query: 349 ALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDR 408
L G+ +I+ T G+ ++ K +AA +F++ D
Sbjct: 925 VCFLGGSWLIQNRRATFGEFFQVFFALTLTAVGVTQTSTMAPDINKAKDSAASIFDILDS 984
Query: 409 KPLIHPTIGKDPVT-LENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGG 467
KP I + K + + + I HV F YP RP IF DL T+ G+ V +VG SG
Sbjct: 985 KPKIDSSSEKGTILPIVHGDIELQHVSFRYPMRPDIQIFSDLCLTISSGQTVALVGESGS 1044
Query: 468 GKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYA 527
GKSTV SLL R+YD SG+I L I+ L R +G+V QEP+LF+ TI NI Y
Sbjct: 1045 GKSTVISLLERFYDPDSGKILLDQVEIQSLKLSWLREQMGLVSQEPVLFNETIGSNIAYG 1104
Query: 528 VPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLD 587
+E I A AN F+++ P G +T+VG RG QLSGGQKQRIA+ARA L D
Sbjct: 1105 KIGGATEEE--IITAAKAANVHNFISSLPQGYETSVGERGVQLSGGQKQRIAIARAILKD 1162
Query: 588 PSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTV 647
P IL+LDEATSALD++SE VV +L Q +TT+ +AH ++TI+ + + V+ ++G +
Sbjct: 1163 PKILLLDEATSALDAESERVVQDALDQVMV-NRTTVVVAHLLTTIKDADMIAVV-KNGVI 1220
Query: 648 AETGSFDKLIAIPDSSLNKLLS 669
AE+G + L+ I + L++
Sbjct: 1221 AESGRHETLMEISGGAYASLVA 1242
Score = 251 bits (640), Expect = 4e-66
Identities = 165/500 (33%), Positives = 258/500 (51%), Gaps = 15/500 (3%)
Query: 175 VTGERLVARLRTRTMKAALEQDATFLD-HNRVGDLISRLSSDAGIVSKSVTQNLSDGTRA 233
VTGER R+R +K L QD F D G++I R+S D ++ S+ + + T+
Sbjct: 102 VTGERQSTRIRRLYLKTILRQDIGFFDTETNTGEVIGRMSGDTILIQDSMGEKVGKFTQL 161
Query: 234 VIQGFVGFGMMSFISWKLTCVMMLLAPPL----GVMALVYGKRIRNLSRQLQTSVGELTK 289
V GF + + KLT ++ P + G M + K+ ++++Q + E
Sbjct: 162 VSSFVGGFTVAFIVGMKLTLALLPCVPLIVGTGGAMTYIMSKK----AQRVQLAYTEAGN 217
Query: 290 VSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLA 349
V ++ + + +T+ A+ GEK+ + +Y ++ + +K+ L SG G+ V
Sbjct: 218 VVQQAVGSIRTVVAFTGEKQSMGKYEKKLEIAYKSMVKQGLYSGLGIGIMMVVVYCTYGF 277
Query: 350 LLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRK 409
+ G I T G + + + + G AA ++FE RK
Sbjct: 278 AIWYGARQIIEKGYTGGQVMNVITSILTGGMALGQTLPSLNSFAAGTAAAYKMFETIKRK 337
Query: 410 PLIHPTIGKDPVTLENKS-IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGG 468
P I V E K I V F YP RP IF + TV G V +VG SG G
Sbjct: 338 PKIDAYDMSGEVLEEIKGDIELRDVYFRYPARPDVQIFVGFSLTVPNGMTVALVGQSGSG 397
Query: 469 KSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAV 528
KSTV SL+ R+YD SGE+ + +++ F ++ R +G+V QEP+LF+ TI +NI Y
Sbjct: 398 KSTVISLIERFYDPESGEVLIDGIDLKKFQVKWIRSKIGLVSQEPILFATTIRENIVYGK 457
Query: 529 PQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDP 588
+ I A+ AN + F+ P GL+T VG GTQLSGGQKQRIA+ARA L +P
Sbjct: 458 KDA---SDQEIRTALKLANASNFIDKLPQGLETMVGEHGTQLSGGQKQRIAIARAILKNP 514
Query: 589 SILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVA 648
IL+LDEATSALD++SE +V +L + +TT+ +AHR++TI+ + + V+ + G V
Sbjct: 515 KILLLDEATSALDAESERIVQDAL-VKLMLSRTTVVVAHRLTTIRTADMIAVV-QQGKVI 572
Query: 649 ETGSFDKLIAIPDSSLNKLL 668
E G+ D++I P+ + ++L+
Sbjct: 573 EKGTHDEMIKDPEGTYSQLV 592
>7303208 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1313
Score = 253 bits (647), Expect = 5e-67
Identities = 165/511 (32%), Positives = 257/511 (50%), Gaps = 10/511 (1%)
Query: 152 YTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDH--NRVGDLI 209
Y + G+ V +A +I + GERL RLR +A L Q+ + D N G L
Sbjct: 793 YFLIAGIVV--GIATFLQIYFFGIAGERLTERLRGLMFEAMLRQEVAWFDDKANGTGSLC 850
Query: 210 SRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVY 269
+RLS DA V + Q + +++ +G + + W L V + P + + +
Sbjct: 851 ARLSGDAAAVQGATGQRIGTIVQSISTLALGIALSMYYEWSLGLVALAFTPFILIAFYMQ 910
Query: 270 GKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEA 329
+ + ++ TK++ E +S +T+ + E+ Y + + +
Sbjct: 911 RTLMAKENMGSAKTMENCTKLAVEVVSNIRTVASLGREEMFHQNYIGMLIPAVEISKRNT 970
Query: 330 LTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXX 389
G +G+ + A A + GT + + GD+ +
Sbjct: 971 HFRGLVYGLARSLMFFAYAACMYYGTWCVIHRGILFGDVFKVSQALIMGTASIANALAFA 1030
Query: 390 XELMKGAGAAARVFELNDRKPLI--HPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFE 447
+ KG AA +F R+P I P + +DP E + F+ VKFSYPTR + + +
Sbjct: 1031 PNMQKGVSAAKTIFTFLRRQPSIVDRPGVSRDPWHSEGY-VRFDKVKFSYPTRSEIQVLK 1089
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLG 507
L V G+ + +VGPSG GKST L+ R+YD+ G + ++R+ ++ R LG
Sbjct: 1090 GLELAVSKGQKIALVGPSGCGKSTCIQLIQRFYDVDEGATLIDECDVRNVSMTNLRNQLG 1149
Query: 508 VVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRG 567
+V QEP+LF TI +NI+Y V D+ IS A ++N +F+AN P G T +G +G
Sbjct: 1150 IVSQEPILFDRTIRENISYGDNARNVTDQEIIS-ACKKSNIHEFIANLPLGYDTRMGEKG 1208
Query: 568 TQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAH 627
QLSGGQKQRIA+ARA + +P I++LDEATSALD++SE+VV +L S G+TTISIAH
Sbjct: 1209 AQLSGGQKQRIAIARALIRNPKIMLLDEATSALDAESEKVVQDALDAAS-EGRTTISIAH 1267
Query: 628 RVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
R+ST+ HS VI + +G V E G +L+A
Sbjct: 1268 RLSTVVHSD-VIFVFENGLVCEAGDHKQLLA 1297
Score = 249 bits (637), Expect = 8e-66
Identities = 160/498 (32%), Positives = 260/498 (52%), Gaps = 23/498 (4%)
Query: 181 VARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVG 240
+ +R++ ++ L QD + D N+ G++ SR++ D + + + + ++ FVG
Sbjct: 176 ILTIRSKFFRSILHQDMKWYDFNQSGEVASRMNEDLSKMEDGLAEKVVMFVHYLV-AFVG 234
Query: 241 FGMMSFIS-WKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATK 299
+++F+ W+L+ V + P + + L+++ T V+E LS +
Sbjct: 235 SLVLAFVKGWQLSLVCLTSLPLTFIAMGLVAVATSRLAKKEVTMYAGAAVVAEGALSGIR 294
Query: 300 TIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIK 359
T++A+ GE KE+ Y + V + +K + SG FG+ F + G ++
Sbjct: 295 TVKAFEGEAKEVAAYKERVVAAKILNIKRNMFSGIGFGLLWFFIYASYALAFWYGVGLVI 354
Query: 360 TGL-------MTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLI 412
G G + + + GA A+VF + ++ P I
Sbjct: 355 KGYHEPAYENYDAGTMITVFFSVMMGSMNIGMAAPYIEAFGIAKGACAKVFHIIEQIPEI 414
Query: 413 HPTIGK-----DPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGG 467
+P G+ +P+T +I F V+F YPTRP+ I LN + G+ V +VGPSG
Sbjct: 415 NPIDGEGKKLNEPLT----TIEFKEVEFQYPTRPEVSILNKLNLKIHRGQTVALVGPSGC 470
Query: 468 GKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYA 527
GKST L+ R+YD +G + N++D ++ R +GVV QEP+LF+ +I +NI Y
Sbjct: 471 GKSTCIQLVQRFYDPQAGNLLFNGTNLKDLDINWLRSRIGVVGQEPILFATSIYENIRYG 530
Query: 528 VPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLD 587
++ +E I A AN F+ P G T VG RG QLSGGQKQRIA+ARA + D
Sbjct: 531 -REDATREE--IEAAAAAANAAIFIKKLPKGYDTLVGERGAQLSGGQKQRIAIARALIRD 587
Query: 588 PSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTV 647
P IL+LDEATSALD+ SE V +L++ SA G+TTI +AHR+ST++ + R++V+N+ G V
Sbjct: 588 PEILLLDEATSALDTASEAKVQAALEKVSA-GRTTIIVAHRLSTVRRADRIVVINK-GEV 645
Query: 648 AETGSFDKLIAIPDSSLN 665
E+G+ +L+ + D N
Sbjct: 646 VESGTHQELMELKDHYFN 663
>At4g25960 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1233
Score = 253 bits (645), Expect = 9e-67
Identities = 156/496 (31%), Positives = 267/496 (53%), Gaps = 9/496 (1%)
Query: 176 TGERLVARLRTRTMKAALEQDATFLDHNR-VGDLISRLSSDAGIVSKSVTQNLSDGTRAV 234
TGER A++R +++ L QD + D G++IS ++SD +V ++++ + + +
Sbjct: 107 TGERQAAKMRRAYLRSMLSQDISLFDTEASTGEVISAITSDILVVQDALSEKVGNFLHYI 166
Query: 235 IQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQ 294
+ GF + W+++ V + + P + + +Y L +++ S + +++EE
Sbjct: 167 SRFIAGFAIGFTSVWQISLVTLSIVPLIALAGGIYAFVAIGLIARVRKSYIKAGEIAEEV 226
Query: 295 LSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTG 354
+ +T+QA+ GE++ + Y + + + G K LT G G V ++ L+
Sbjct: 227 IGNVRTVQAFTGEERAVRLYREALENTYKYGRKAGLTKGLGLGSMHCVLFLSWALLVWFT 286
Query: 355 TSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHP 414
+ ++ + G + M+ V ++ AA +F++ +R +
Sbjct: 287 SVVVHKDIADGGKSFTTMLNVVIAGLSLGQAAPDISAFVRAKAAAYPIFKMIERNT-VTK 345
Query: 415 TIGKDPVTLENKSIH--FNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTV 472
T K L H F FSYP+RP IF+ LN + G+ V +VG SG GKSTV
Sbjct: 346 TSAKSGRKLGKVDGHIQFKDATFSYPSRPDVVIFDRLNLAIPAGKIVALVGGSGSGKSTV 405
Query: 473 ASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQEL 532
SL+ R+Y+ SG + L +NI + +++ R +G+V QEP LF+ TI +NI Y
Sbjct: 406 ISLIERFYEPISGAVLLDGNNISELDIKWLRGQIGLVNQEPALFATTIRENILYGKDDAT 465
Query: 533 VNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILI 592
+ I+RA + F+ N P+G +T VG RG QLSGGQKQRIA++RA + +PSIL+
Sbjct: 466 AEE---ITRAAKLSEAISFINNLPEGFETQVGERGIQLSGGQKQRIAISRAIVKNPSILL 522
Query: 593 LDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGS 652
LDEATSALD++SE+ V ++L R G+TT+ +AHR+ST++++ +I + G + E G+
Sbjct: 523 LDEATSALDAESEKSVQEAL-DRVMVGRTTVVVAHRLSTVRNAD-IIAVVHEGKIVEFGN 580
Query: 653 FDKLIAIPDSSLNKLL 668
+ LI+ PD + + LL
Sbjct: 581 HENLISNPDGAYSSLL 596
Score = 252 bits (644), Expect = 1e-66
Identities = 172/503 (34%), Positives = 270/503 (53%), Gaps = 24/503 (4%)
Query: 177 GERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSSDAGIVSKSVTQNLSDGTRAV 234
GERL R+R +A L+ + + D N L SRL SDA ++ V D + +
Sbjct: 738 GERLTLRVRENMFRAILKNEIGWFDEVDNTSSMLASRLESDATLLKTIVV----DRSTIL 793
Query: 235 IQGFVGFGMMSFI-----SWKLTCVMMLLAPPLGVMALVYGKR-IRNLSRQLQTSVGELT 288
+Q +G + SFI +W+LT V+ L PL + + K ++ L + +
Sbjct: 794 LQN-LGLVVTSFIIAFILNWRLTLVV-LATYPLVISGHISEKLFMQGYGGDLNKAYLKAN 851
Query: 289 KVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALL 348
++ E +S +T+ A+C E+K + Y+ E+ + + +G F+GV+ F +
Sbjct: 852 MLAGESVSNIRTVAAFCAEEKILELYSRELLEPSKSSFRRGQIAGLFYGVSQFFIFSSYG 911
Query: 349 ALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDR 408
L G++++ GL + M + +L+KG A VFE+ DR
Sbjct: 912 LALWYGSTLMDKGLAGFKSVMKTFMVLIVTALAMGETLALAPDLLKGNQMVASVFEILDR 971
Query: 409 KPLIHPTIGKDPVTLENK--SIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSG 466
K I +G+ L N +I V FSYP+RP IF D + VR G+ + +VG SG
Sbjct: 972 KTQI---VGETSEELNNVEGTIELKGVHFSYPSRPDVVIFRDFDLIVRAGKSMALVGQSG 1028
Query: 467 GGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITY 526
GKS+V SL+LR+YD +G++ + +I+ +L+ R+ +G+VQQEP LF+ TI +NI Y
Sbjct: 1029 SGKSSVISLILRFYDPTAGKVMIEGKDIKKLDLKALRKHIGLVQQEPALFATTIYENILY 1088
Query: 527 AVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLL 586
++ + + AN F+ + P+G T VG RG Q+SGGQ+QRIA+ARA L
Sbjct: 1089 GNEGA---SQSEVVESAMLANAHSFITSLPEGYSTKVGERGVQMSGGQRQRIAIARAILK 1145
Query: 587 DPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGT 646
+P+IL+LDEATSALD +SE VV Q+L + A +TT+ +AHR+STI+++ + VL+ G
Sbjct: 1146 NPAILLLDEATSALDVESERVVQQALDRLMA-NRTTVVVAHRLSTIKNADTISVLH-GGK 1203
Query: 647 VAETGSFDKLIAIPDSSLNKLLS 669
+ E GS KL+ KL+S
Sbjct: 1204 IVEQGSHRKLVLNKSGPYFKLIS 1226
>CE06485 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1238
Score = 251 bits (642), Expect = 2e-66
Identities = 155/492 (31%), Positives = 261/492 (52%), Gaps = 9/492 (1%)
Query: 172 ILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGT 231
+ K G+ RLR + + L++DA + D G L + L+ + ++ + ++
Sbjct: 120 LFKYIGDNTTYRLRHKFILRLLKKDAKYFDTISTGYLSTVLNDNLERFREAFNEKIAFII 179
Query: 232 RAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVS 291
+G + + SW L + A + + L+ + + + ++
Sbjct: 180 CFSTDFAIGTALAFYTSWTLASYGSVFAFGIVISGLLNSTSMMKSNEKQSMHYSNAGAIA 239
Query: 292 EEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALL 351
+ L + KT+ + G+ +E+ +Y+ E+++ G + A G++ F N +L
Sbjct: 240 FQALCSFKTVISLNGQTQELEKYSAELKEGEKFGSRRAFFLATSRGLSHFFCNALNGTIL 299
Query: 352 LTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPL 411
G +I M + + Y + L+ +A +F++
Sbjct: 300 YVGADLIYNKTMNTVAIVTLFHYMLFSAFSLGEAFLHISYLLNAINSATPIFDVLTSDDD 359
Query: 412 IHPTIGKDPVTLENKSIH----FNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGG 467
+ + T NK+I FN+VKF+YP+RP I ++F V+ GE + +VG SG
Sbjct: 360 MIENNQDNEQTDSNKTIQGMLSFNNVKFAYPSRPDVDILRGISFDVKQGECIALVGASGS 419
Query: 468 GKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYA 527
GKST+ LLL +Y+I SG IK+G+ ++ D NL++ R +GVV QEP+LF+ TI +NI +
Sbjct: 420 GKSTIVQLLLHFYNIQSGTIKIGDSHLHDINLKQLRNAIGVVSQEPVLFNTTIEENIRFG 479
Query: 528 VPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLD 587
P + I A+ +AN F+ N DGL+T VG RG QLSGGQKQRIA+AR + +
Sbjct: 480 NPNA---TSSEIYEALRKANAYDFVCNIKDGLKTIVGERGAQLSGGQKQRIAIARVLVKN 536
Query: 588 PSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTV 647
P+IL+LDEATSALDS SE V +L ++++ G+TTI IAHR+STI+H +++V++ +G +
Sbjct: 537 PAILLLDEATSALDSASERAVQLAL-KKASEGRTTIIIAHRLSTIRHCDKIMVMS-NGKI 594
Query: 648 AETGSFDKLIAI 659
AE GS ++LI++
Sbjct: 595 AEVGSHEELISM 606
Score = 212 bits (540), Expect = 1e-54
Identities = 146/484 (30%), Positives = 238/484 (49%), Gaps = 11/484 (2%)
Query: 178 ERLVARLRTRTMKAALEQDATFLDHNRVGD--LISRLSSDAGIVSKSVTQNLSDGTRAVI 235
E+L RLR ++ + L F D + L++RL++D + +V L +++
Sbjct: 750 EKLSTRLRIKSFQHLLSLPCAFYDDPKHSPTRLVNRLNTDPSNIKAAVDARLGSLLMSMV 809
Query: 236 QGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQL 295
+ + + SWKLT +L +Y K ++ + K++ E L
Sbjct: 810 SFSLAILIACYYSWKLTLQAILY-----YAKFLYKKTTTISIKEDSVAFENSNKIAIEVL 864
Query: 296 SATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGT 355
KT++A E + I+ + + + + ++ G G + + GT
Sbjct: 865 DNMKTVKALNMEARVINLVMEYLAVLKTSYPRRSVVMGLANGFSAGCSQIVYAISFKFGT 924
Query: 356 SMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPT 415
+I + D+ ++ + K +A +F L +
Sbjct: 925 YLILQKEVIPMDMYLSLITLSYTSNMAGSAISYMPDFRKAIHSAGLIFNLFTYPATMPFN 984
Query: 416 IGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASL 475
++ ++ +VKF Y RP + + + +N V G+ + IVGPSG GKST+ SL
Sbjct: 985 SDTGSRSITKGEVNGENVKFHYHQRPDYTVLDSVNLKVEAGKTLAIVGPSGSGKSTIISL 1044
Query: 476 LLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVND 535
L +Y G IK+ NDN+ + NL R LG+V Q P+LF+ +I DNI Y + + +
Sbjct: 1045 LEMFYRADQGFIKIDNDNVENINLDHLRSNLGLVSQGPVLFNCSIRDNILYGLTRNI--S 1102
Query: 536 ETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDE 595
+T I A+ AN F+ P GL T VG RG QLSGGQKQRIA+ RA L +P +L+LDE
Sbjct: 1103 QTEIENALQIANAFNFVFQLPQGLDTIVGDRGAQLSGGQKQRIAITRAILRNPKLLLLDE 1162
Query: 596 ATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDK 655
ATSALD++SE++V +L S R +TI +AHR+STI ++ + VL R+G V E G+ ++
Sbjct: 1163 ATSALDTESEKIVQNALDTASER-LSTIVVAHRLSTIINADSIAVL-RNGKVVEQGTHNQ 1220
Query: 656 LIAI 659
L+A+
Sbjct: 1221 LLAV 1224
>CE03262 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1327
Score = 248 bits (633), Expect = 2e-65
Identities = 165/534 (30%), Positives = 283/534 (52%), Gaps = 28/534 (5%)
Query: 142 MIFGLTSTQF--------YTALG-GVFVVGALANVGRIVILKVTGERLVARLRTRTMKAA 192
+++ TS QF Y LG G+F+ ++ N + + + R++A++R R + +
Sbjct: 134 LVYPPTSKQFRNKANENVYIFLGIGIFI--SITNFIQYMCFQHCCTRVMAQMRHRFVYSV 191
Query: 193 LEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGF---VGFGMMSFI-S 248
L Q+A + D N G + ++L+ + + + + D +++GF + ++++I
Sbjct: 192 LRQNAGWFDKNHSGTITTKLNDSM----ERIREGIGDKLGVLLRGFAMLIAAIVVAYIYE 247
Query: 249 WKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEK 308
W+L +M+ +AP + + +++ + + + VG+ ++EE L +T+QA+ G++
Sbjct: 248 WRLASMMLGVAPTCCICMSLLARQMTSTTIKELIGVGKAGSIAEESLMGVRTVQAFNGQE 307
Query: 309 KEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTV-GD 367
+ + RY E+ K + + SG F G+ F L +L G ++K G++T GD
Sbjct: 308 EMVGRYEAELEKGRKFAVWKGFWSGFFGGLFFFWLFSFLGCGMLYGAYLLKVGIITTPGD 367
Query: 368 LSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENK- 426
+ +M + L+ +AA +++ DR P I P K L+N
Sbjct: 368 VFIVVMSMLLGAYFLGLISPHMMVLLNARVSAASIYQTIDRVPKIDP-YSKAGKRLQNVV 426
Query: 427 -SIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSG 485
+ F +V F YP+R I LN V PG V +VG SG GKST LL R Y+ +G
Sbjct: 427 GRVKFENVHFRYPSRKDAKILNGLNLVVEPGTSVALVGHSGCGKSTSVGLLTRLYEPEAG 486
Query: 486 EIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQ 545
+ + ++R+ N+ R +G+VQQEP+LF+ TI +N+ P ET I
Sbjct: 487 NVTIDGTDVRELNIEWLRNTVGIVQQEPILFNDTIHNNLLIGNPGS--TRETMI-EVCKM 543
Query: 546 ANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSE 605
AN F+ P G T +G G QLSGGQKQR+A+AR + DP +L+LDEATSALD+QSE
Sbjct: 544 ANAHDFIEKMPKGYDTLIGDGGVQLSGGQKQRVAIARTLIRDPKVLLLDEATSALDAQSE 603
Query: 606 EVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAI 659
+V QS +++G+TTI IAHR+STI+ + +++ + G + E G+ ++L+ +
Sbjct: 604 SIV-QSALNNASKGRTTIMIAHRLSTIREADKIVFFEK-GVIVEAGNHEELVRL 655
Score = 229 bits (584), Expect = 1e-59
Identities = 161/496 (32%), Positives = 252/496 (50%), Gaps = 23/496 (4%)
Query: 171 VILKVTGERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSSDAGIVSKSVTQNLS 228
V+ V E L R R ++ + L QDA++ D+ + G LI+RL+SDA + V +
Sbjct: 829 VLFAVVSENLSMRFRVQSFRNLLYQDASYFDNPAHAPGKLITRLASDAPNIKAVVDARML 888
Query: 229 DGTRAVIQGFVGFGMMSFISWKL----TCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSV 284
A+ + W++ T +++LLA ++ L Y + N+ +
Sbjct: 889 QVIYALAAIIANIAIAFIYCWQIGILGTSLILLLA--FVMIGLAYKISLMNVEQIQNDDA 946
Query: 285 GELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGN 344
G +++ E + KTIQ + Y ++ LK+ + + +T
Sbjct: 947 G---RIAIEIIENVKTIQLLTRCELFFDHYQTSSKQQKRSELKKGMIEAINYSLTQSFMY 1003
Query: 345 VALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFE 404
+ G +I G + D ++ + E +K AA +F
Sbjct: 1004 FMMCFTYAVGIRIIYQGDKSSDDTFKGIIAMMLGAVAVMNSAQYFPEFVKAKTAAGMLFN 1063
Query: 405 LNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGP 464
+ RKP + D + +I F +VKFSYP RP I + L +T G+ V +VGP
Sbjct: 1064 IIYRKPRTGDLMEGDRPEIRG-NILFENVKFSYPQRPLQPIMKGLQWTALRGQTVALVGP 1122
Query: 465 SGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNI 524
SG GKST +L R+YD+ G +++ +IR +L R + +V QEP LF+GTI +N+
Sbjct: 1123 SGSGKSTNIGMLERFYDVTGGALRIDGQDIRKLSLFHLRTQMALVGQEPRLFAGTIRENV 1182
Query: 525 TYA---VPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALA 581
VP E +N +A+ AN +FLAN P G+ T VG +G QLSGGQKQRIA+A
Sbjct: 1183 CLGLKDVPLEKIN------QALELANANRFLANLPAGIDTDVGEKGGQLSGGQKQRIAIA 1236
Query: 582 RAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVL 641
RA + DP IL+LDEATSALDS+SE V ++L R+ G+T I+IAHR+S+IQ+S ++ +
Sbjct: 1237 RALVRDPKILLLDEATSALDSESERAVQEAL-DRAREGRTCITIAHRLSSIQNSDLIVYI 1295
Query: 642 NRHGTVAETGSFDKLI 657
++ G V E G+ +L+
Sbjct: 1296 DK-GKVQEAGNHTQLM 1310
>CE29212 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1265
Score = 247 bits (631), Expect = 4e-65
Identities = 163/519 (31%), Positives = 265/519 (50%), Gaps = 28/519 (5%)
Query: 151 FYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLIS 210
+Y LG V+ + +I + ERLV +LR +KA L Q + D + G+L +
Sbjct: 116 YYLVLG---VLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTA 172
Query: 211 RLSSDAGIVSKSVTQNLSDGTRAVIQGFV----GFGMMSFISWKLTCVMMLLAPPLGVMA 266
RL+ D + V + L D ++Q F G+G+ F SW +T VMM AP + +
Sbjct: 173 RLTDDL----ERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSG 228
Query: 267 LVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGL 326
K + +R Q + ++EE S+ +T+ + G K+E+ R+ + + VG
Sbjct: 229 AKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALE----VGR 284
Query: 327 KEALTSGAFFGVTGFVGNVAL-----LALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXX 381
+ + + G+ N+ + LA T +I G + + +
Sbjct: 285 QTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTS 344
Query: 382 XXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKS--IHFNHVKFSYPT 439
GAA+ V + + P I P + + ++N I F V F YP+
Sbjct: 345 LGGALPHLASFGTARGAASTVLRVINSHPKIDP-YSLEGILVDNMKGDISFKDVHFRYPS 403
Query: 440 RPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNL 499
R H+ + ++ ++ G+ + +VG SG GKST+ +LL R+YD G + + ++R+ N+
Sbjct: 404 RKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNV 463
Query: 500 RKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGL 559
R +G+V QEP+LF GTI +NI + +D+ + A AN F+ PDG
Sbjct: 464 HSLREQIGIVSQEPVLFDGTIYENIKMG-NEHATHDQ--VVEACKMANANDFIKRLPDGY 520
Query: 560 QTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARG 619
T VG +G QLSGGQKQRIA+ARA + +P IL+LDEATSALD+++E V +L Q A G
Sbjct: 521 GTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQAQA-G 579
Query: 620 KTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
+TTI +AHR+STI++ R+ V + G + E+GS ++L++
Sbjct: 580 RTTIIVAHRLSTIRNVDRIFVF-KAGNIVESGSHEELMS 617
Score = 229 bits (583), Expect = 1e-59
Identities = 167/514 (32%), Positives = 256/514 (49%), Gaps = 22/514 (4%)
Query: 152 YTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNR--VGDLI 209
+ +G F VG + L GE L +LR K L QD F D R G L
Sbjct: 747 FVLMGITFFVGFFTSAN---CLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLC 803
Query: 210 SRLSSDAGIVSKSVTQ-NLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGV---- 264
+R ++DA V T+ + + I G +G G + W+L +++++ P L +
Sbjct: 804 TRFATDAPNVRYVFTRLPVVLASIVTICGALGIGF--YYGWQLALILVVMVPLLVMGGYF 861
Query: 265 -MALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFH 323
M + +GK+IR+ QL G KV+ + + +T+ + +++ Y + +R+ F+
Sbjct: 862 EMQMRFGKQIRDT--QLLEEAG---KVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFN 916
Query: 324 VGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXX 383
LK A T GA F + + A G+ + M D+
Sbjct: 917 TNLKHAHTYGAVFAFSQSLIFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIG 976
Query: 384 XXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQH 443
+++K AA+ +F L + I V +I +V F+YPTR
Sbjct: 977 NTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDT 1036
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYR 503
+ + ++ G+ V +VG SG GKST+ LL R+Y+ G I + DNIR+ N+ R
Sbjct: 1037 KVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLR 1096
Query: 504 RLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTV 563
+ +V QEP LF TI +NI Y + + E I A AN F+ PDG T V
Sbjct: 1097 EQVCIVSQEPTLFDCTIGENICYGTNRNVTYQE--IVEAAKMANIHNFILGLPDGYDTHV 1154
Query: 564 GPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTI 623
G +GTQLSGGQKQRIA+ARA + PS+L+LDEATSALD++SE++V ++L + +G+T +
Sbjct: 1155 GEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEAL-DAAKQGRTCL 1213
Query: 624 SIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
IAHR+STIQ+S VI + G + E G+ D+LI
Sbjct: 1214 VIAHRLSTIQNSD-VIAIVSEGKIVEKGTHDELI 1246
>CE03818 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1268
Score = 247 bits (631), Expect = 4e-65
Identities = 157/488 (32%), Positives = 269/488 (54%), Gaps = 12/488 (2%)
Query: 178 ERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQG 237
ER + +R + +K+ L QDA + D +G L ++SS + + + V
Sbjct: 125 ERRLHCIRKKYLKSVLRQDAKWFDETTIGGLTQKMSSGIEKIKDGIGDKVGVLVGGVATF 184
Query: 238 FVGFGMMSFISWKLTCVMMLLAP-PLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLS 296
G + ++ W+LT VMM+ P LG M L K + ++ ++ ++ E ++
Sbjct: 185 ISGVSIGFYMCWQLTLVMMITVPLQLGSMYLS-AKHLNRATKNEMSAYSNAGGMANEVIA 243
Query: 297 ATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTS 356
+T+ A+ + EI+RYA ++ + +G+++A+ + + G +
Sbjct: 244 GIRTVMAFNAQPFEINRYAHQLNEARRMGIRKAIILAICTAFPLMLMFTCMAVAFWYGAT 303
Query: 357 MIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAAR-VFELNDRKPLIHPT 415
+ G ++ G + + + +AV + GA A +F++ D +P I T
Sbjct: 304 LAAAGAVSSGAVFA-VFWAVLIGTRRLGEAAPHLGAITGARLAIHDIFKVIDHEPEIKCT 362
Query: 416 I--GKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVA 473
GK P ++ K + F+ ++F+YPTRP+ I + ++F V PGE V +VG SG GKST
Sbjct: 363 SSEGKIPEKIQGK-LTFDGIEFTYPTRPELKILKGVSFEVNPGETVALVGHSGCGKSTSI 421
Query: 474 SLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELV 533
LL+R+Y+ +G IKL I+++N+R R +G+VQQEP++F T+ +NI + L+
Sbjct: 422 GLLMRFYNQCAGMIKLDGIPIQEYNIRWLRSTIGIVQQEPIIFVATVAENI--RMGDVLI 479
Query: 534 NDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILIL 593
D+ I A AN +F+ D T +G QLSGGQKQR+A+ARA + P IL+L
Sbjct: 480 TDQD-IEEACKMANAHEFICKLSDRYDTVIGAGAVQLSGGQKQRVAIARAIVRKPQILLL 538
Query: 594 DEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSF 653
DEATSALD++SE +V Q+ +++ G+TT+ IAHR+STI+++S+++V ++ G +AE G+
Sbjct: 539 DEATSALDTESERMV-QTALDKASEGRTTLCIAHRLSTIRNASKILVFDQ-GLIAERGTH 596
Query: 654 DKLIAIPD 661
D+LI+ D
Sbjct: 597 DELISKDD 604
Score = 228 bits (580), Expect = 3e-59
Identities = 150/490 (30%), Positives = 255/490 (51%), Gaps = 9/490 (1%)
Query: 172 ILKVTGERLVARLRTRTMKAALEQDATFLDHNR--VGDLISRLSSDAGIVSKSVTQNLSD 229
+L GE + RLR + ++QDA++ D +R VG L SRL++DA V ++ Q L++
Sbjct: 771 LLGKAGETMSGRLRMDVFRNIMQQDASYFDDSRHNVGSLTSRLATDAPNVQAAIDQRLAE 830
Query: 230 GTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTK 289
++ F G G+ + W + + + A L V+ + ++ ++ S E ++
Sbjct: 831 VLTGIVSLFCGVGVAFYYGWNMAPIGLATALLLVVVQSSVAQYLKFRGQRDMDSAIEASR 890
Query: 290 VSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLA 349
+ E +S KT+QA ++ + + + L F + G
Sbjct: 891 LVTESISNWKTVQALTKQEYMYDAFTAASKSPHRRAIVRGLWQSLSFALAGSFVMWNFAI 950
Query: 350 LLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRK 409
+ G +I T + + E ++ +A +F + +K
Sbjct: 951 AYMFGLWLISNNWSTPYTVFQVIEALNMASMSVMLAASYFPEYVRARISAGIMFTMIRQK 1010
Query: 410 PLI-HPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGG 468
+I + + D T++ +I+ V F+YP R + + + N + G+ V +VGPSG G
Sbjct: 1011 SVIDNRGLTGDTPTIKG-NINMRGVYFAYPNRRRQLVLDGFNMSANFGQTVALVGPSGCG 1069
Query: 469 KSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAV 528
KST L+ RYYD G +K+ + +IRD +++ R + +V QEP LF+ TI +NITY +
Sbjct: 1070 KSTTIQLIERYYDALCGSVKIDDSDIRDLSVKHLRDNIALVGQEPTLFNLTIRENITYGL 1129
Query: 529 PQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDP 588
+ + D+ + +A AN F+ PDG T+VG G +LSGGQKQR+A+ARA + DP
Sbjct: 1130 -ENITQDQ--VEKAATLANIHTFVMGLPDGYDTSVGASGGRLSGGQKQRVAIARAIVRDP 1186
Query: 589 SILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVA 648
IL+LDEATSALD++SE++V ++L ++ G+T + IAHR+STIQ++ ++IV R+G
Sbjct: 1187 KILLLDEATSALDTESEKIVQEAL-DKARLGRTCVVIAHRLSTIQNADKIIVC-RNGKAI 1244
Query: 649 ETGSFDKLIA 658
E G+ L+A
Sbjct: 1245 EEGTHQTLLA 1254
>CE03308 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1266
Score = 244 bits (624), Expect = 3e-64
Identities = 154/484 (31%), Positives = 263/484 (53%), Gaps = 12/484 (2%)
Query: 178 ERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQG 237
ER + +R +++ L QDA + D N VG L ++SS + + + +
Sbjct: 123 ERRLYCIRKHLLQSVLRQDAKWFDENTVGGLTQKMSSGIEKIKDGIGDKIGVLVSGIATF 182
Query: 238 FVGFGMMSFISWKLTCVMMLLAP-PLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLS 296
G + ++ W+LT VM++ P LG M L K + ++ ++ ++ E ++
Sbjct: 183 ISGVALGFYMCWQLTLVMLVTVPLQLGSMYLS-AKHLNRATKNEMSAYSSAGGMANEVIA 241
Query: 297 ATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTS 356
+T+ A+ + EI RY ++ K +G+++A+ + F+ V + G
Sbjct: 242 GIRTVIAFNAQPFEIERYGAQLAKARKMGIRKAIVLALCSAMPLFLMFVLMAGAFWYGAI 301
Query: 357 MIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAAR-VFELNDRKPLIHPT 415
+ G+ T G + +AV + GA A +F++ D +P I+ T
Sbjct: 302 LTSYGVATSGTTFG-VFWAVILGTRRLGEAAPHMGAITGARLAVNDIFKVIDHEPEINCT 360
Query: 416 I--GKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVA 473
G+ P + K + F++++F+YPTRP I + ++F V PGE + +VG SG GKST
Sbjct: 361 KQEGRRPDKVNGKLV-FDNIQFTYPTRPDVKILKGVSFEVNPGETIALVGHSGCGKSTSI 419
Query: 474 SLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELV 533
LL+R+Y+ +G IKL I D+N++ R +G+VQQEP++F T+ +N+ + + +
Sbjct: 420 GLLMRFYNQCAGSIKLDGIPIEDYNIQWLRSTIGIVQQEPIIFLATVAENV--RMGDDSI 477
Query: 534 NDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILIL 593
D+ I A QAN F+ +G T +G QLSGGQKQR+A+ARA + P IL+L
Sbjct: 478 TDKD-IENACRQANAHDFIGKLSEGYNTVIGAGAVQLSGGQKQRVAIARAIVRKPQILLL 536
Query: 594 DEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSF 653
DEATSALD++SE +V Q+ +++ G+TT+ IAHR+STI+++S+++V ++ G + E G
Sbjct: 537 DEATSALDTESERMV-QTALDKASEGRTTLCIAHRLSTIRNASKILVFDQ-GLIPERGIH 594
Query: 654 DKLI 657
D+LI
Sbjct: 595 DQLI 598
Score = 230 bits (586), Expect = 6e-60
Identities = 162/498 (32%), Positives = 265/498 (52%), Gaps = 25/498 (5%)
Query: 172 ILKVTGERLVARLRTRTMKAALEQDATFLD---HNRVGDLISRLSSDAGIVSKSVTQNLS 228
+L TGE + +RLR K ++QDAT+ D HN VG+L SRL++D+ V ++ L+
Sbjct: 769 LLGKTGETMSSRLRMDVFKNIMQQDATYFDDPKHN-VGNLTSRLATDSQNVQAAIDHRLA 827
Query: 229 DGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELT 288
+ V+ F G + + W + + ++ A L + + ++ + S E +
Sbjct: 828 EVLNGVVSLFTGIAVAFWFGWSMAPIGLITALLLVIAQSAVAQYLKYRGPKDMESAIEAS 887
Query: 289 KVSEEQLSATKTIQAYCGEKKEIHRYA----DEVRKVFHVGLKEALTSGAFFGVTG--FV 342
++ E +S KT+QA ++ H + + ++ F GL ++L+ F + G F+
Sbjct: 888 RIVTESISNWKTVQALTKQEYMFHAFTAASKNPRKRAFTKGLWQSLS----FALAGSFFL 943
Query: 343 GNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARV 402
N A+ + G +I T + + E ++ +A +
Sbjct: 944 WNFAIAYMF--GLWLISNNWTTPFAVFQVIEALNMASMSVMMAASYFPEYVRARISAGIM 1001
Query: 403 FELNDRKPLI--HPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVC 460
F + +K I G+ P I V F+YP R + I + N + + GE V
Sbjct: 1002 FTMIRQKAKIDNRGLTGETPDI--RGDISMKGVYFAYPNRNRQLILNNFNMSAQFGETVA 1059
Query: 461 IVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTI 520
+VGPSG GKST L+ RYYD G +K+ + +IRD +++ R + +V QEP LF+ TI
Sbjct: 1060 LVGPSGCGKSTSIQLIERYYDAICGAVKIDDHDIRDISVKHLRHNIALVGQEPTLFNLTI 1119
Query: 521 LDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIAL 580
+NITY + E V+ E ++ +A AN F+ N P+G T+VG G +LSGGQKQRIA+
Sbjct: 1120 RENITYGL--ENVSQE-QVEKAATLANIHSFVENLPEGYDTSVGASGGRLSGGQKQRIAI 1176
Query: 581 ARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIV 640
ARA + +P IL+LDEATSALD++SE++V ++L ++ G+T + IAHR+STIQ++ ++IV
Sbjct: 1177 ARAIVRNPKILLLDEATSALDTESEKIVQEAL-DKARLGRTCVVIAHRLSTIQNADKIIV 1235
Query: 641 LNRHGTVAETGSFDKLIA 658
R+G E G+ L+A
Sbjct: 1236 C-RNGKAIEEGTHQTLLA 1252
>Hs9665248 [U] KOG0058 Peptide exporter ABC superfamily
Length = 808
Score = 243 bits (621), Expect = 6e-64
Identities = 144/477 (30%), Positives = 256/477 (53%), Gaps = 5/477 (1%)
Query: 182 ARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGF 241
+ L+ A L Q+ F N+ G+++SR++ D +S S+++NLS +++G
Sbjct: 318 SHLQGEVFGAVLRQETEFFQQNQTGNIMSRVTEDTSTLSDSLSENLSLFLWYLVRGLCLL 377
Query: 242 GMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTI 301
G+M + S LT V ++ P L ++ GK + L Q++ S+ + ++V+ E LSA T+
Sbjct: 378 GIMLWGSVSLTMVTLITLPLLFLLPKKVGKWYQLLEVQVRESLAKSSQVAIEALSAMPTV 437
Query: 302 QAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTG 361
+++ E+ E ++ ++++++ + KEA+ T G + + +L G ++ +G
Sbjct: 438 RSFANEEGEAQKFREKLQEIKTLNQKEAVAYAVNSWTTSISGMLLKVGILYIGGQLVTSG 497
Query: 362 LMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPV 421
++ G+L +F++Y + + K G++ ++FE DR P P+ P+
Sbjct: 498 AVSSGNLVTFVLYQMQFTQAVEVLLSIYPRVQKAVGSSEKIFEYLDRTPRCPPSGLLTPL 557
Query: 422 TLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYD 481
LE + F V F+YP RP + + L FT+RPGE +VGP+G GKSTVA+LL Y
Sbjct: 558 HLEG-LVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQ 616
Query: 482 IGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISR 541
G++ L + + R R + V QEP +F ++ +NI Y + Q+ +E I+
Sbjct: 617 PTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEE--ITA 674
Query: 542 AIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALD 601
A ++ F++ P G T V G+QLSGGQ+Q +ALARA + P +LILD+ATSALD
Sbjct: 675 AAVKSGAHSFISGLPQGYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALD 734
Query: 602 SQSEEVVAQSLQQRSAR-GKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ S+ V Q L + R ++ + I +S ++ + ++ L G + E G+ +L+
Sbjct: 735 ANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQADHILFL-EGGAIREGGTHQQLM 790
>CE03263 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1270
Score = 243 bits (619), Expect = 1e-63
Identities = 159/516 (30%), Positives = 267/516 (50%), Gaps = 20/516 (3%)
Query: 152 YTALG-GVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLIS 210
Y LG G+FV + N + + + R++A++R R + + L Q+A + D + G + +
Sbjct: 146 YIFLGIGIFVT--ITNYIQYMCFQHCCSRIMAQMRHRYVYSVLRQNAGWFDKHHSGTIAT 203
Query: 211 RLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPP-LGVMALVY 269
+L+ + + + L R V + W+L C+++ +AP +G M+L+
Sbjct: 204 KLNDSMERIREGIGDKLGVLLRGVAMLVASVVVAYIYEWRLACMLLGVAPTCIGCMSLMA 263
Query: 270 GKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEA 329
+ ++L V + ++EE L +T+QA+ G+++ + RY E+ K G K A
Sbjct: 264 RQMTATTVKELG-GVEKAGSIAEESLMGVRTVQAFNGQEEMVERYRVELNK----GRKFA 318
Query: 330 LTSGAFFGVTGFVGNVALLAL----LLTGTSMIKTGLM-TVGDLSSFMMYAVXXXXXXXX 384
+ G + G+ G + L A L G ++ G++ + GD+ +M +
Sbjct: 319 IWKGFWSGLFGGMFFFWLFAFQGCGFLYGAYLLSVGIIKSPGDVFIIVMAMLLGSYFTGL 378
Query: 385 XXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDP-VTLENKSIHFNHVKFSYPTRPQH 443
L+ AA ++E DR P I P K + + F +V F YPTR
Sbjct: 379 ISPHLMVLLNARVAAGSIYETIDRVPKIDPYSKKGKFLDKVIGRVKFENVHFRYPTRKDA 438
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYR 503
I LN T+ PG V +VG SG GKST LL R Y+ +G + + ++R+ N+ R
Sbjct: 439 KILNGLNLTIEPGTSVALVGHSGCGKSTSVGLLTRLYEPEAGNVTIDGTDVRELNIDYLR 498
Query: 504 RLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTV 563
++G+VQQEP+LF+ TI +N+ P ++ AN F+ P G T +
Sbjct: 499 NVIGIVQQEPILFNDTIHNNLLLGNPNA---TREKMIEVCKMANAHDFIEKMPKGYDTMI 555
Query: 564 GPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTI 623
G G QLSGGQKQR+A+AR + +P +L+LDEATSALD+QSE +V QS +++G+TTI
Sbjct: 556 GDGGVQLSGGQKQRVAIARTLVREPKVLLLDEATSALDAQSESIV-QSALNNASKGRTTI 614
Query: 624 SIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAI 659
IAHR+STI+ + +++ + G + E G+ ++L+ +
Sbjct: 615 MIAHRLSTIREADKIVFFEK-GVIVEAGNHEELVRL 649
Score = 205 bits (522), Expect = 2e-52
Identities = 123/272 (45%), Positives = 169/272 (61%), Gaps = 14/272 (5%)
Query: 391 ELMKGAGAAARVFELNDRKPLIHPTI-GKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDL 449
E +K AA +F + RKP + G P N I F +VKFSYP RP I + L
Sbjct: 993 EFVKAKTAAGLLFNIIYRKPRTGDLLEGSRPEVRGN--ILFENVKFSYPQRPHQPIMKGL 1050
Query: 450 NFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVV 509
+T G+ V +VGPSG GKST +L R+YD+ G +++ +IR +L R + +V
Sbjct: 1051 QWTALRGQTVALVGPSGSGKSTCIGMLERFYDVTGGTLRIDGQDIRGLSLFHLRTQMALV 1110
Query: 510 QQEPMLFSGTILDNITYA---VPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPR 566
QEP LF+GTI +NI VP E +N A+ AN +FLAN P G++T VG +
Sbjct: 1111 GQEPRLFAGTIKENICLGLENVPMEKIN------HALELANANRFLANLPAGIETDVGEK 1164
Query: 567 GTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIA 626
G++LSGGQKQRIA+ARA + DP IL+LDEATSALDS+SE V ++L R+ G+T I+IA
Sbjct: 1165 GSKLSGGQKQRIAIARALVRDPKILLLDEATSALDSESERAVQEAL-DRAREGRTCITIA 1223
Query: 627 HRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
HR+S+IQ+S VIV +G V E G+ +L++
Sbjct: 1224 HRLSSIQNSD-VIVYIENGRVQEAGNHKQLMS 1254
>At1g70610 [U] KOG0058 Peptide exporter ABC superfamily
Length = 659
Score = 242 bits (618), Expect = 1e-63
Identities = 158/466 (33%), Positives = 249/466 (52%), Gaps = 15/466 (3%)
Query: 196 DATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVM 255
D +F D VGDL SRL SD VS+ + +L+ R V+QG + +SW L
Sbjct: 189 DISFFDSQTVGDLTSRLGSDCQQVSRVIGNDLNMIFRNVLQGTGALIYLLILSWPLGLCT 248
Query: 256 MLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYA 315
+++ L + VYG + ++ +Q +V++E S +T++ Y EK+E RY
Sbjct: 249 LVICCILAAVMFVYGMYQKKTAKLIQEITASANEVAQETYSLMRTVRVYGTEKQEFKRYN 308
Query: 316 DEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYA 375
++++ + L+++ G + + + + +L G I G +T L+ F++Y+
Sbjct: 309 HWLQRLADISLRQSAAYGIWNWSFNTLYHATQIIAVLVGGLSILAGQITAEQLTKFLLYS 368
Query: 376 VXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKF 435
LM+ GA+ +VF++ D KP + + I F V F
Sbjct: 369 EWLIYATWWVGDNLSSLMQSVGASEKVFQMMDLKP-------RTRLQRLTGHIEFVDVSF 421
Query: 436 SYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIR 495
SYP+R + + +++N +V PGE V IVG SG GKST+ +LLL+ Y+ SG+I L ++
Sbjct: 422 SYPSRDEVAVVQNVNISVHPGEVVAIVGLSGSGKSTLVNLLLQLYEPTSGQILLDGVPLK 481
Query: 496 DFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANF 555
+ +++ R+ +G V QEP LF I NI Y + + ++ I A QA F+
Sbjct: 482 ELDVKWLRQRIGYVGQEPKLFRTDISSNIKYGCDRNISQED--IISAAKQAYAHDFITAL 539
Query: 556 PDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSE---EVVAQSL 612
P+G T V LSGGQKQRIA+ARA L DP ILILDEATSALD++SE + V +S+
Sbjct: 540 PNGYNTIVD--DDLLSGGQKQRIAIARAILRDPRILILDEATSALDAESEHNVKGVLRSI 597
Query: 613 QQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
SA ++ I IAHR+STIQ + R++ ++ G V E GS +L++
Sbjct: 598 GNDSATKRSVIVIAHRLSTIQAADRIVAMD-SGRVVEMGSHKELLS 642
>Hs9961246 [U] KOG0058 Peptide exporter ABC superfamily
Length = 703
Score = 242 bits (617), Expect = 2e-63
Identities = 150/467 (32%), Positives = 245/467 (52%), Gaps = 9/467 (1%)
Query: 176 TGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVI 235
T R+ R+R + + L QD F + G+L SRLSSD ++S + N + R+++
Sbjct: 217 TMSRINLRIREQLFSSLLRQDLGFFQETKTGELNSRLSSDTTLMSNWLPLNANVLLRSLV 276
Query: 236 QGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQL 295
+ +G M IS +LT + +L P VY R + + R++Q +V +V E +
Sbjct: 277 KVVGLYGFMLSISPRLTLLSLLHMPFTIAAEKVYNTRHQEVLREIQDAVARAGQVVREAV 336
Query: 296 SATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGT 355
+T++++ E+ E+ RY + + + + + L + + + + +L G
Sbjct: 337 GGLQTVRSFGAEEHEVCRYKEALEQCRQLYWRRDLERALYLLIRRVLHLGVQMLMLSCGL 396
Query: 356 SMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPT 415
++ G +T G L SFM+Y +++ GAA +VF DR+P +
Sbjct: 397 QQMQDGELTQGSLLSFMIYQESVGSYVQTLVYIYGDMLSNVGAAEKVFSYMDRQPNLPSP 456
Query: 416 IGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASL 475
P TL+ + F V F+YP RP + + L FT+RPGE +VGP+G GKSTVA+L
Sbjct: 457 GTLAPTTLQGV-VKFQDVSFAYPNRPDRPVLKGLTFTLRPGEVTALVGPNGSGKSTVAAL 515
Query: 476 LLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVND 535
L Y G++ L I + + V QEP+LFSG++ +NI Y + +
Sbjct: 516 LQNLYQPTGGQVLLDEKPISQYEHCYLHSQVVSVGQEPVLFSGSVRNNIAYGLQS---CE 572
Query: 536 ETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDE 595
+ ++ A A+ F+ G+ T VG +G+QL+ GQKQR+A+ARA + DP +LILDE
Sbjct: 573 DDKVMAAAQAAHADDFIQEMEHGIYTDVGEKGSQLAAGQKQRLAIARALVRDPRVLILDE 632
Query: 596 ATSALDSQSEEVVAQSLQQRSARG-KTTISIAHRVSTIQHSSRVIVL 641
ATSALD Q E Q+LQ ++RG +T + IAHR+ +Q + +++VL
Sbjct: 633 ATSALDVQCE----QALQDWNSRGDRTVLVIAHRLQAVQRAHQILVL 675
>At4g18050 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1323
Score = 242 bits (617), Expect = 2e-63
Identities = 153/449 (34%), Positives = 236/449 (52%), Gaps = 14/449 (3%)
Query: 210 SRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVY 269
S + S G + QN++ T +I F +W L +++ L+P + +
Sbjct: 823 STVRSLVGDALALIVQNIATVTTGLIIAFTA-------NWILALIVLALSPFIVIQGYAQ 875
Query: 270 GKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEA 329
K + S + E ++V+ + +S+ +T+ ++C E+K + Y + G++
Sbjct: 876 TKFLTGFSADAKAMYEEASQVANDAVSSIRTVASFCAEEKVMDLYQQKCDGPKKNGVRLG 935
Query: 330 LTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXX 389
L SGA FG + F ++G +I+ G T G++
Sbjct: 936 LLSGAGFGFSFFFLYCINCVCFVSGAGLIQIGKATFGEVFKVFFALTIMAIGVSQTSAMA 995
Query: 390 XELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKS--IHFNHVKFSYPTRPQHHIFE 447
+ K +AA +F++ D P I + + TL+N + I F HV F YP RP IF
Sbjct: 996 PDSNKAKDSAASIFDILDSTPKIDSS-SDEGTTLQNVNGDIEFRHVSFRYPMRPDVQIFR 1054
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLG 507
DL T+ G+ V +VG SG GKSTV S++ R+Y+ SG+I + I+ F L R+ +G
Sbjct: 1055 DLCLTIPSGKTVALVGESGSGKSTVISMIERFYNPDSGKILIDQVEIQTFKLSWLRQQMG 1114
Query: 508 VVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRG 567
+V QEP+LF+ TI NI Y +E I A AN F+++ P G T+VG RG
Sbjct: 1115 LVSQEPILFNETIRSNIAYGKTGGATEEE--IIAAAKAANAHNFISSLPQGYDTSVGERG 1172
Query: 568 TQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAH 627
QLSGGQKQRIA+ARA L DP IL+LDEATSALD++SE VV +L R +TT+ +AH
Sbjct: 1173 VQLSGGQKQRIAIARAILKDPKILLLDEATSALDAESERVVQDAL-DRVMVNRTTVVVAH 1231
Query: 628 RVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
R++TI+++ VI + ++G +AE G + L
Sbjct: 1232 RLTTIKNAD-VIAVVKNGVIAEKGRHETL 1259
Score = 235 bits (599), Expect = 2e-61
Identities = 156/496 (31%), Positives = 252/496 (50%), Gaps = 7/496 (1%)
Query: 175 VTGERLVARLRTRTMKAALEQDATFLD-HNRVGDLISRLSSDAGIVSKSVTQNLSDGTRA 233
VTGER A +R +K L QD + D G++I R+S D ++ ++ + + T+
Sbjct: 100 VTGERQSATIRGLYLKTILRQDIGYFDTETNTGEVIGRMSGDTILIQDAMGEKVGKFTQL 159
Query: 234 VIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEE 293
+ GF + + L V+ P + + + ++ + Q + E V E+
Sbjct: 160 LCTFLGGFAIAFYKGPLLAGVLCSCIPLIVIAGAAMSLIMSKMAGRGQVAYAEAGNVVEQ 219
Query: 294 QLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLT 353
+ A +T+ A+ GEK+ +Y ++ + +++ L SG G V + +
Sbjct: 220 TVGAIRTVVAFTGEKQATEKYESKLEIAYKTVVQQGLISGFGLGTMLAVIFCSYGLAVWY 279
Query: 354 GTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIH 413
G +I G + + + + G AA ++FE R P I
Sbjct: 280 GAKLIMEKGYNGGQVINVIFAVLTGGMSLGQTSPSLNAFAAGRAAAFKMFETIKRSPKID 339
Query: 414 PTIGKDPVTLENKS-IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTV 472
V + + I V F YP RP IF + V G+ V +VG SG GKSTV
Sbjct: 340 AYDMSGSVLEDIRGDIELKDVYFRYPARPDVQIFAGFSLFVPNGKTVALVGQSGSGKSTV 399
Query: 473 ASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQEL 532
SL+ R+YD SG++ + N +++ L+ R +G+V QEP+LF+ TI +NI Y +E
Sbjct: 400 ISLIERFYDPESGQVLIDNIDLKKLQLKWIRSKIGLVSQEPVLFATTIKENIAYG--KED 457
Query: 533 VNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILI 592
D+ I AI AN KF+ P GL T VG GTQ+SGGQKQR+A+ARA L +P IL+
Sbjct: 458 ATDQ-EIRTAIELANAAKFIDKLPQGLDTMVGEHGTQMSGGQKQRLAIARAILKNPKILL 516
Query: 593 LDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGS 652
LDEATSALD++SE +V +L + +TT+ +AHR++TI+ ++ VI + G + E G+
Sbjct: 517 LDEATSALDAESERIVQDALVNLMS-NRTTVVVAHRLTTIR-TADVIAVVHQGKIVEKGT 574
Query: 653 FDKLIAIPDSSLNKLL 668
D++I P+ + ++L+
Sbjct: 575 HDEMIQDPEGAYSQLV 590
>CE05221 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1283
Score = 241 bits (616), Expect = 2e-63
Identities = 153/491 (31%), Positives = 257/491 (52%), Gaps = 10/491 (2%)
Query: 172 ILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGT 231
I+K G+ +R + + L +D ++ D G L L+ + + + ++
Sbjct: 148 IMKFVGDNTAYNVRRQYISRLLRKDISYFDGMSTGHLSIVLNDNMERFREVFNEKIALII 207
Query: 232 RAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALV--YGKRIRNLSRQLQTSVGELTK 289
+ +G + + W+L C + + + + L+ +GK ++N +Q + +
Sbjct: 208 ALLTDFVIGTILAFYTDWRLACYGTVFSFGIVLSGLLDSWGK-MKNNEKQNE-HISNAGS 265
Query: 290 VSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLA 349
++ + L KT+ + G+++E+ RY +E++ L A F N
Sbjct: 266 IAFQALGCYKTVSSLNGQQQEVERYTEELKNGEKYALNRAFVFSLSRSADYFFTNALNFV 325
Query: 350 LLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFE-LNDR 408
+L G +MI G + G + + Y + L + + L D
Sbjct: 326 ILYFGANMIYEGTIEPGVVVRILYYILFGSYCLGEAILHISRLASAIPLTVPIADILLDS 385
Query: 409 KPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGG 468
++ I F +V FSYPTRP + ++++F V+ GE + +VG SG G
Sbjct: 386 DATADEFFSEEIKDTFQGIISFKNVLFSYPTRPDVPVLKEISFNVQGGECIALVGASGSG 445
Query: 469 KSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAV 528
KSTV LLL YY+I SG I + ++I + N+++ R+ +GVV QEP+LF+ +I +NI +
Sbjct: 446 KSTVIQLLLHYYNIDSGRISIDGNDIYNINIKQLRQAMGVVFQEPVLFNTSIEENIRFGK 505
Query: 529 PQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDP 588
P E I A+ AN F+ NFPDG++T VG RG QLSGGQKQRIA+AR + +P
Sbjct: 506 PDA---TEQEIIDALKNANAFDFVCNFPDGIKTIVGERGAQLSGGQKQRIAIARTLVRNP 562
Query: 589 SILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVA 648
IL+LDEATSALD++SE +V ++LQ+ S G+TTI +AHR+STI++++++IV+ + G +
Sbjct: 563 RILLLDEATSALDNESEFIVQEALQKASI-GRTTIVVAHRLSTIRNANKIIVMEK-GEIV 620
Query: 649 ETGSFDKLIAI 659
E G +LIA+
Sbjct: 621 EVGDHKQLIAM 631
Score = 213 bits (543), Expect = 6e-55
Identities = 142/484 (29%), Positives = 235/484 (48%), Gaps = 6/484 (1%)
Query: 176 TGERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSSDAGIVSKSVTQNLSDGTRA 233
T E+L +LR+ + K + F D + L +RL++D+ V+ +V L
Sbjct: 782 TAEKLSIKLRSMSFKHLMSLPCAFYDDPCHTATRLSNRLNADSSNVTAAVDDRLGSVIMT 841
Query: 234 VIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEE 293
++ + M F SWK++ +++ P L + + + + + + + E
Sbjct: 842 LVAILLAVIMSFFYSWKMSLQVLMFCPLLYLAGYCNDNFVDQAVEEDSIAFEKSNRAAIE 901
Query: 294 QLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLT 353
L +T++A E + I ++K+ + K A+ G G
Sbjct: 902 ALENVRTVRALNMENRVILLVTSHLQKIRNSYFKRAVIQGTANGFACSCYFFIYAVSFKF 961
Query: 354 GTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIH 413
GT ++ + D +M + K AA +F L ++
Sbjct: 962 GTWLVLREEILPMDTYLVLMTLSMTASYAGSAVAYLPDHRKAIHAAGLIFHLFTYPAIMP 1021
Query: 414 PTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVA 473
+ ++N I +V F Y R I + ++ + G + +VGPSG GKST+
Sbjct: 1022 YDSSQGKRNIKNGEIELKNVSFEYAQRSDKMILDGVSLKLPAGRTLALVGPSGSGKSTII 1081
Query: 474 SLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELV 533
SLL R+Y GE+K+ +N+ D NL R + +V QEP+LF+ +I +N + +
Sbjct: 1082 SLLERFYHAVDGEVKIDEENVVDVNLHHLRESVSLVSQEPVLFNCSIKENFLFGISHNA- 1140
Query: 534 NDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILIL 593
+ I +A+ AN F++ FP GL T VG RG QLSGGQKQRIA+ARA L +P +L+L
Sbjct: 1141 -SQLEIDQALKVANAFSFVSQFPQGLDTLVGERGAQLSGGQKQRIAIARAILRNPKVLLL 1199
Query: 594 DEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSF 653
DEATSALDS SE+VV +L S R +T+ +AHR+ST+ ++ + VL ++G VAE G+
Sbjct: 1200 DEATSALDSDSEKVVQNALDTASER-LSTVVVAHRLSTVVNADSIAVL-KNGKVAEQGTH 1257
Query: 654 DKLI 657
++L+
Sbjct: 1258 EELL 1261
>SPCC663.03 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1362
Score = 239 bits (610), Expect = 1e-62
Identities = 155/486 (31%), Positives = 251/486 (50%), Gaps = 12/486 (2%)
Query: 178 ERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSSDAGIVSKSVTQNLSDGTR-AV 234
E ++ R+R + L QD F D N VG + + LS+ I S + GT +
Sbjct: 865 EAVLQRIRYHLFRTLLRQDVEFFDRSENTVGAITTSLSTK--IQSLEGLSGPTLGTFFQI 922
Query: 235 IQGFVGFGMMSFIS-WKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEE 293
+ + ++S + WKL V + +P + + + + +L + E + E
Sbjct: 923 LTNIISVTILSLATGWKLGLVTLSTSPVIITAGYYRVRALDQVQEKLSAAYKESAAFACE 982
Query: 294 QLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLT 353
SA +T+ + E+ Y D + K +L SG FF V +
Sbjct: 983 STSAIRTVASLNREENVFAEYCDSLIKPGRESAIASLKSGLFFSAAQGVTFLINALTFWY 1042
Query: 354 GTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIH 413
G+++++ G + + + V ++ K AA + L++ KP I
Sbjct: 1043 GSTLMRKGEYNIVQFYTCFIAIVFGIQQAGQFFGYSADVTKAKAAAGEIKYLSESKPKID 1102
Query: 414 P--TIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKST 471
T GK +L++ +I F V+FSYPTR + LN TV+PG+ V VG SG GKST
Sbjct: 1103 TWSTEGKKVESLQSAAIEFRQVEFSYPTRRHIKVLRGLNLTVKPGQFVAFVGSSGCGKST 1162
Query: 472 VASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQE 531
L+ R+YD +G + + N+RD+N+ YR+ + +V QEP L+ GT+ +NI ++
Sbjct: 1163 TIGLIERFYDCDNGAVLVDGVNVRDYNINDYRKQIALVSQEPTLYQGTVRENIVLGASKD 1222
Query: 532 LVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSIL 591
+ +E + A +AN +F+ P+G T G +G+ LSGGQKQRIA+ARA + +P IL
Sbjct: 1223 VSEEE--MIEACKKANIHEFILGLPNGYNTLCGQKGSSLSGGQKQRIAIARALIRNPKIL 1280
Query: 592 ILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETG 651
+LDEATSALDS SE+VV ++L S +G+TT++IAHR+S+IQ + + V + G +AE G
Sbjct: 1281 LLDEATSALDSHSEKVVQEALNAAS-QGRTTVAIAHRLSSIQDADCIFVFD-GGVIAEAG 1338
Query: 652 SFDKLI 657
+ +L+
Sbjct: 1339 THAELV 1344
Score = 223 bits (567), Expect = 1e-57
Identities = 148/491 (30%), Positives = 240/491 (48%), Gaps = 11/491 (2%)
Query: 175 VTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAV 234
+ GER+ R+R + A L Q+ + D G++ +R+++D + + + + A+
Sbjct: 166 IAGERIARRIRQDYLHAILSQNIGYFDRLGAGEITTRITTDTNFIQDGLGEKVGLVFFAI 225
Query: 235 IQGFVGFGMMSFISWKLTCVMMLLAPPL-GVMALVYGKRIRNLSRQLQTSVGELTKVSEE 293
GF + WK T ++ + P + G + L +N Q+ V E + EE
Sbjct: 226 ATFVSGFVIAFIRHWKFTLILSSMFPAICGGIGLGVPFITKNTKGQIAV-VAESSTFVEE 284
Query: 294 QLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLT 353
S + A+ + Y + G+ +A+ G G FV
Sbjct: 285 VFSNIRNAFAFGTQDILAKLYNKYLITAQRFGINKAIAMGLMVGWMFFVAYGVYGLAFWE 344
Query: 354 GTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIH 413
G ++ G + V L + + A AA ++F+ DR I+
Sbjct: 345 GGRLLHAGDLDVSKLIGCFFAVLIASYSLANISPKMQSFVSCASAAKKIFDTIDRVSPIN 404
Query: 414 PTIGKDPVTLENKS-IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTV 472
V + K I +++F YPTRP+ + ++ + G+ +VG SG GKST+
Sbjct: 405 AFTPTGDVVKDIKGEIELKNIRFVYPTRPEVLVLDNFSLVCPSGKITALVGASGSGKSTI 464
Query: 473 ASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQEL 532
L+ R+YD G++ L ++R N+ R + +VQQEP+LF+ T+ +NITY +P +
Sbjct: 465 IGLVERFYDPIGGQVFLDGKDLRTLNVASLRNQISLVQQEPVLFATTVFENITYGLPDTI 524
Query: 533 VND------ETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLL 586
E R+ A AN F+ P+ T VG RG +SGGQKQRIA+ARA +
Sbjct: 525 KGTLSKEELERRVYDAAKLANAYDFIMTLPEQFSTNVGQRGFLMSGGQKQRIAIARAVIS 584
Query: 587 DPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGT 646
DP IL+LDEATSALDS+SE +V ++L S R +TTI IAHR+STI+++ ++V+N G
Sbjct: 585 DPKILLLDEATSALDSKSEVLVQKALDNAS-RSRTTIVIAHRLSTIRNADNIVVVNA-GK 642
Query: 647 VAETGSFDKLI 657
+ E GS ++L+
Sbjct: 643 IVEQGSHNELL 653
>CE03261 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1291
Score = 238 bits (608), Expect = 2e-62
Identities = 165/515 (32%), Positives = 261/515 (50%), Gaps = 45/515 (8%)
Query: 147 TSTQFYTALG-GVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRV 205
T Y LG G+FV ++ + + + + R++ +R R + + L Q+A + D N
Sbjct: 135 TMENVYIFLGLGIFV--SINDFCQYMCFQRVCSRMMTVMRNRYISSILRQNAGWFDKNLS 192
Query: 206 GDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVM 265
G + +RL+ + + V L R + + W+L +M+ L P +
Sbjct: 193 GTITTRLNDNMERIQDGVGDKLGVLIRGISMVIASVVISLIYEWRLALMMLGLIPVSTIC 252
Query: 266 ALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVG 325
+ + + + + VGE ++EE L +TIQA+ G+++ + +Y K + G
Sbjct: 253 MTLLSRFLEKSTGEELEKVGEAGAIAEECLMGVRTIQAFNGQEEMVAKY----EKQLNSG 308
Query: 326 LKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTG-LMTVGDLSSFMMYAVXXXXXXXX 384
K A+ G + G G + L+A + G ++ G L+ VG + S
Sbjct: 309 KKHAIWGGFWSGFFGGIFFFWLMAFM--GCGILYGGYLLKVGIIKS-------------- 352
Query: 385 XXXXXXELMKGAGAAARVFELNDRKPLIHPTI--GKDPVTLENKSIHFNHVKFSYPTRPQ 442
AA +++ DR P I P GK + K + F +V F YPTR +
Sbjct: 353 -------------PAASIYKTIDRVPKIDPYSRHGKKIEKVVGK-VTFENVHFRYPTRKE 398
Query: 443 HHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKY 502
+ LN TV PG V +VG SG GKST LL R Y+ G +++ ++RD NL
Sbjct: 399 AKVLNGLNLTVEPGTSVALVGHSGCGKSTSVGLLTRLYEPEQGSVQIDGVDVRDLNLEWL 458
Query: 503 RRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTT 562
R ++G+VQQEP+LF+ TI +N+ + P ET I R AN F+ P G T
Sbjct: 459 RNVVGIVQQEPILFNDTIHNNLLFGNPD--ATRETMI-RVCKMANAHDFIKKMPKGYDTQ 515
Query: 563 VGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTT 622
+G G QLSGGQKQR+A+AR + DP +L+LDEATSALD+QSE VV QS +++G+TT
Sbjct: 516 IGDGGVQLSGGQKQRVAIARTLIRDPKVLLLDEATSALDAQSESVV-QSALNNASKGRTT 574
Query: 623 ISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
I IAHR+STI+ + +++ + G + E G+ ++L+
Sbjct: 575 IMIAHRLSTIREADKIVFFEK-GVIVEAGNHEELV 608
Score = 225 bits (574), Expect = 2e-58
Identities = 162/504 (32%), Positives = 259/504 (51%), Gaps = 35/504 (6%)
Query: 171 VILKVTGERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSSDAGIVSKSVTQNLS 228
V+ + E L R R + L QDA + D+ + G LI+RL++D V V +
Sbjct: 793 VMFAIVSENLGVRFRVAAFRNLLYQDAAYFDNPAHAPGSLITRLAADPPCVKAVVDGRMM 852
Query: 229 D---GTRAVIQ----GFVGFGMMSFISWKLTCVMMLLAPPLGV-MALVYGKRIRNLSRQL 280
T AVI GF+ ++ + L ++ + L +++V + + N
Sbjct: 853 QVVYATAAVIACVTIGFINCWQVAILGTALIFLLGFIMAGLAFKISIVAAEHMEN----- 907
Query: 281 QTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVT- 339
+ K++ E + KTIQ ++ ++ Y +E +K L++++ + ++
Sbjct: 908 ----DDAGKIAIEIIENVKTIQLLTRTRRFLNSYENESKKRKRTELRKSVYEAVNYCISQ 963
Query: 340 GFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAA 399
F+ ++ L +I G TV +M + + + AA
Sbjct: 964 NFMYYMSCFCFALA-IRIINQGDQTVDKTFRCLMAMMLCCEGIIMSAQFFPQFVGAKSAA 1022
Query: 400 ARVFELNDRKPLIHPT-IGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEH 458
++F L +R+P G P N I F +VKFSYP RP + + L +T G+
Sbjct: 1023 GQMFNLINRQPQTGDLKSGTKPEIRGN--ILFENVKFSYPQRPHQPVMKQLQWTALRGQT 1080
Query: 459 VCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSG 518
V +VGPSG GKST +L R+YD+ G +++ +I++ +L R + +V QEP LF G
Sbjct: 1081 VALVGPSGSGKSTCIGMLERFYDVTGGALRMDGQDIKNISLYHLRTQMALVGQEPRLFVG 1140
Query: 519 TILDNITYA---VPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQK 575
TI +N+ VP E +N +A+ AN +FL N PDG+ T VG RG QLSGGQK
Sbjct: 1141 TIRENVCLGLKDVPLEKIN------QALELANANRFLGNLPDGIDTEVGERGGQLSGGQK 1194
Query: 576 QRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHS 635
QRIA+ARA + DP IL+LDEATSALDS+SE V ++L R+ G+T I+IAHR+S+IQ+S
Sbjct: 1195 QRIAIARALVRDPKILLLDEATSALDSESERAVQEAL-DRAREGRTCITIAHRLSSIQNS 1253
Query: 636 SRVIVLNRHGTVAETGSFDKLIAI 659
++ ++ G V E+G+ +L+ +
Sbjct: 1254 DLIVYID-DGRVQESGTHKELMQL 1276
>7303379 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1279
Score = 235 bits (599), Expect = 2e-61
Identities = 163/516 (31%), Positives = 262/516 (50%), Gaps = 25/516 (4%)
Query: 157 GVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLD--HNRVGDLISRLSS 214
G+ ++ L N+ + + G ++ RLR R + QD + D N VG L SRL+S
Sbjct: 761 GIGLMAGLGNMLQTYMFTTAGVKMTTRLRKRAFGTIIGQDIAYFDDERNSVGALCSRLAS 820
Query: 215 DAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIR 274
D V + + +AV VG + SW+ T + ++ P + + + G+ I
Sbjct: 821 DCSNVQGATGARVGTMLQAVATLVVGMVVGFVFSWQQTLLTLVTLPLVCLSVYLEGRFIM 880
Query: 275 NLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEV--------RKVFHVGL 326
+++ + S+ E ++V+ E ++ +T+ C E++ + +Y ++ RKV GL
Sbjct: 881 KSAQKAKASIEEASQVAVEAITNIRTVNGLCLERQVLDQYVQQIDRVDIACRRKVRFRGL 940
Query: 327 KEALTSGAFF---GVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXX 383
AL A F G++ + G + + + +IK ++ +++
Sbjct: 941 VFALGQAAPFLAYGISMYYGGILVAEERMNYEDIIK--------VAEALIFGSWMLGQAL 992
Query: 384 XXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQH 443
+ + AG +F+ +P P + V I + +V F YPTR
Sbjct: 993 AYAPNVNDAILSAGRLMDLFKRTSTQPN-PPQSPYNTVEKSEGDIVYENVGFEYPTRKGT 1051
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYR 503
I + LN T++ V +VGPSG GKST LLLRYYD SG + L +F L R
Sbjct: 1052 PILQGLNLTIKKSTTVALVGPSGSGKSTCVQLLLRYYDPVSGSVNLSGVPSTEFPLDTLR 1111
Query: 504 RLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTV 563
LG+V QEP+LF TI +NI Y I A ++N F++ P G T +
Sbjct: 1112 SKLGLVSQEPVLFDRTIAENIAYGNNFRDDVSMQEIIEAAKKSNIHNFISALPQGYDTRL 1171
Query: 564 GPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTI 623
G + +QLSGGQKQRIA+ARA + +P ILILDEATSALD +SE+VV Q+L + + G+T +
Sbjct: 1172 G-KTSQLSGGQKQRIAIARALVRNPKILILDEATSALDLESEKVVQQALDE-ARSGRTCL 1229
Query: 624 SIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAI 659
+IAHR++T++++ + VL R G V E G+ D+L+A+
Sbjct: 1230 TIAHRLTTVRNADLICVLKR-GVVVEHGTHDELMAL 1264
Score = 227 bits (579), Expect = 4e-59
Identities = 162/521 (31%), Positives = 263/521 (50%), Gaps = 26/521 (4%)
Query: 153 TALGGVFVVGALANVGRIVILKVTGERL----VARLRTRTMKAALEQDATFLDHNRVGDL 208
TA G +VG++A I + R+ + R+R ++A L QD + D + +
Sbjct: 116 TAFGIGSLVGSVAMFLLITLAIDLANRIALNQIDRIRKLFLEAMLRQDIAWYDTSSGSNF 175
Query: 209 ISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALV 268
S+++ D + + + + + ++ +G WKLT V++ P + V
Sbjct: 176 ASKMTEDLDKLKEGIGEKIVIVVFLIMTFVIGIVSAFVYGWKLTLVVLSCVPFIIAATSV 235
Query: 269 YGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKE 328
+ +L+ + S + V EE S +T+ A+ G++KE R+ + + G K+
Sbjct: 236 VARLQGSLAEKELKSYSDAANVVEEVFSGIRTVFAFSGQEKEKERFGKLLIPAENTGRKK 295
Query: 329 ALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSS---------FMMYAVXXX 379
L SG ++ + + + + G ++I + DL +++AV
Sbjct: 296 GLYSGMGNALSWLIIYLCMALAIWYGVTLI----LDERDLPDRVYTPAVLVIVLFAVIMG 351
Query: 380 XXXXXXXXXXXELMKGAGAAAR-VFELNDRKPLIHPTIGKDPVTLENKSIH--FNHVKFS 436
E + A AA + +F + DR + P K EN + H F ++F
Sbjct: 352 AQNLGFASPHVEAIAVATAAGQTLFNIIDRPSQVDPMDEKGNRP-ENTAGHIRFEGIRFR 410
Query: 437 YPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRD 496
YP RP I + L V PG+ V VG SG GKST+ L+ R+YD +G +KL ++R
Sbjct: 411 YPARPDVEILKGLTVDVLPGQTVAFVGASGCGKSTLIQLMQRFYDPEAGSVKLDGRDLRT 470
Query: 497 FNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFP 556
N+ R +GVV QEP+LF+ TI +NI Y P D + +RA ANC F+ P
Sbjct: 471 LNVGWLRSQIGVVGQEPVLFATTIGENIRYGRPSATQADIEKAARA---ANCHDFITRLP 527
Query: 557 DGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRS 616
G T VG +G Q+SGGQKQRIA+ARA + P +L+LDEATSALD SE+ V QS + +
Sbjct: 528 KGYDTQVGEKGAQISGGQKQRIAIARALVRQPQVLLLDEATSALDPTSEKRV-QSALELA 586
Query: 617 ARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
++G TT+ +AHR+STI ++ +++ L + G VAE G+ ++L+
Sbjct: 587 SQGPTTLVVAHRLSTITNADKIVFL-KDGVVAEQGTHEELM 626
>7295351 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1302
Score = 231 bits (590), Expect = 2e-60
Identities = 162/520 (31%), Positives = 256/520 (49%), Gaps = 12/520 (2%)
Query: 147 TSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLD--HNR 204
T+ + LG F+ G + + + + G L R+R T A + Q+ + D +N
Sbjct: 772 TAVLSWACLGLAFLTGLVCFL-QTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNS 830
Query: 205 VGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGV 264
VG L +RLS +A + ++ LS +A+ + + +WKL + + P +
Sbjct: 831 VGALSARLSGEAVDIQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVG 890
Query: 265 MALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHV 324
++ K + N + + + E +++ E ++ +T+ E I Y +E+++V +
Sbjct: 891 SVILEAKMMSNAVVREKQVIEEACRIATESITNIRTVAGLRREADVIREYTEEIQRVEVL 950
Query: 325 GLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXX 384
++ G A L G ++ G + D+ +
Sbjct: 951 IRQKLRWRGVLNSTMQASAFFAYAVALCYGGVLVSEGQLPFQDIIKVSETLLYGSMMLAQ 1010
Query: 385 XXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENK-----SIHFNHVKFSYPT 439
A R+F++ DRKP I +G TL + + + ++F YPT
Sbjct: 1011 SLAFTPAFSAALIAGHRLFQILDRKPKIQSPMGTIKNTLAKQLNLFEGVRYRGIQFRYPT 1070
Query: 440 RPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIR-DFN 498
RP I L+ V G+ V +VG SG GKST LL RYYD G I + +D+I+ D
Sbjct: 1071 RPDAKILNGLDLEVLKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQHDLT 1130
Query: 499 LRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDG 558
L R LG+V QEP LF +I +NI Y + V+ I A AN F+ + P+G
Sbjct: 1131 LDGVRTKLGIVSQEPTLFERSIAENIAYGDNRRSVS-MVEIIAAAKSANAHSFIISLPNG 1189
Query: 559 LQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSAR 618
T +G RGTQLSGGQKQRIA+ARA + +P IL+LDEATSALD QSE++V Q+L +
Sbjct: 1190 YDTRMGARGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQAL-DTACS 1248
Query: 619 GKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
G+T I IAHR+ST+Q++ VI + ++G V E G+ +LI+
Sbjct: 1249 GRTCIVIAHRLSTVQNAD-VICVIQNGQVVEQGNHMQLIS 1287
Score = 218 bits (555), Expect = 3e-56
Identities = 164/522 (31%), Positives = 262/522 (49%), Gaps = 29/522 (5%)
Query: 160 VVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIV 219
VV ++ + + + + R V R+R + + + QD + D + + D +
Sbjct: 129 VVMFISGIFSVDVFNMVALRQVTRMRIKLFSSVIRQDIGWHDLASKQNFTQSMVDDVEKI 188
Query: 220 SKSVTQNLSDGTRAVIQGFVGFGMMSF-ISWKLTCVMMLLAPPLGVMALVYGKRIRNLSR 278
+++ + V+ GF+ +SF WKLT + P + ++ K L+
Sbjct: 189 RDGISEKVGHFVYLVV-GFIITVAISFSYGWKLTLAVSSYIPLVILLNYYVAKFQGKLTA 247
Query: 279 QLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALT-SGAFFG 337
+ Q S ++EE LS+ +T+ ++ GEK E+ RY + F V ++A GAF G
Sbjct: 248 REQESYAGAGNLAEEILSSIRTVVSFGGEKSEVQRYEN-----FLVPARKASQWKGAFSG 302
Query: 338 VTGFVGNVALLALLLTGTSMIKTGLMTVGDLS--------SFMMYAVXXXXXXXXXXXXX 389
++ V ++L L G L+ + D + + +M A
Sbjct: 303 LSDAVLK-SMLYLSCAGAFWYGVNLI-IDDRNVENKEYTPAILMIAFFGIIVGADNIART 360
Query: 390 XELMKG----AGAAARVFELNDRKPLIHP--TIGKDPVTLENKSIHFNHVKFSYPTRPQH 443
++ G A +F++ D I P T GK + F V F YP+RP+
Sbjct: 361 APFLESFATARGCATNLFKVIDLTSKIDPLSTDGKLLNYGLRGDVEFQDVFFRYPSRPEV 420
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYR 503
+ LN +R G+ V +VG SG GKST LL R+YD G + L + +IR +N++ R
Sbjct: 421 IVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLLQRFYDPVFGSVLLDDLDIRKYNIQWLR 480
Query: 504 RLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTV 563
+ VV QEP+LF GTI NI+Y P + I A QA +F+ N P+ ++ +
Sbjct: 481 SNIAVVGQEPVLFLGTIAQNISYGKPGA---TQKEIEAAATQAGAHEFITNLPESYRSMI 537
Query: 564 GPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTI 623
G RG+QLSGGQKQRIA+ARA + +P IL+LDEATSALD QSE+ V Q+L S +G+TTI
Sbjct: 538 GERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLAS-KGRTTI 596
Query: 624 SIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLN 665
++HR+S I+ + +++ ++ G V E GS D L+A+ + N
Sbjct: 597 VVSHRLSAIRGADKIVFIH-DGKVLEEGSHDDLMALEGAYYN 637
>7295352 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1320
Score = 228 bits (581), Expect = 2e-59
Identities = 173/527 (32%), Positives = 270/527 (50%), Gaps = 43/527 (8%)
Query: 160 VVGALANVGRIV---ILKVTGERLVARLRTRTMKAALEQDATFLDH--NRVGDLISRLSS 214
V+G A V + + G L R+R++T + + Q+ + D N +G L +RLS
Sbjct: 793 VIGIAAGVVCYIQTFFFNLAGVWLTTRMRSKTFRCIMNQEMGWFDRKENSIGALSARLSG 852
Query: 215 DAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFI----SWKLTCVMMLLAPPLGVMALVYG 270
DA V ++ LS+ +IQ F F I SW+L + + +P + V ++V+
Sbjct: 853 DAASVQGAIGFPLSN----IIQAFTNFICSIAIAFPYSWELALICLSTSPFM-VASIVFE 907
Query: 271 KRIRNLSRQLQTSVGELT-KVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEA 329
R S + V E T +++ E ++ +T+ E++ I Y EV + H +
Sbjct: 908 ARFGEKSALKEKEVLEETSRIATETITQIRTVAGLRREEELIKIYDKEVERYRH----QI 963
Query: 330 LTSGAFFGVTGFVGNVALL---ALLLT-GTSMIKTGLM---TVGDLSSFMMYAVXXXXXX 382
L+ + G+ +G + A+ LT G M G + T+ +S+ M+Y +
Sbjct: 964 LSRLKWRGLVNSLGKSLMFFGYAVTLTYGGHMCADGKIKFETIMKISNTMLYGLFILAQS 1023
Query: 383 XXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKD----------PVTLENKSIHFNH 432
+ A R++E+ DRKP I + + + + +
Sbjct: 1024 LAFTPAFNAALLSAN---RMYEIIDRKPQIQSPESFEIQQNGNGTAYKTNVVQQGVSYRG 1080
Query: 433 VKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGND 492
+ FSYP+RP + ++ N + G+ V +VG SG GKST LL+RYYD G+I + +
Sbjct: 1081 LNFSYPSRPHIKVLQNFNLDINQGQTVALVGASGSGKSTCVQLLMRYYDPDEGKILIDQE 1140
Query: 493 NIR-DFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKF 551
+I D +L+ RR LG+V QEP LF +I DNI Y V + +I A AN +F
Sbjct: 1141 SIHHDMDLKTLRRRLGIVSQEPSLFEKSIADNIGYGDTSRQVPMQ-QIIEAAKMANAHEF 1199
Query: 552 LANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQS 611
+ + P T +G +GTQLSGGQKQRIA+ARA + +P IL+LDEATSALD QSE VV Q+
Sbjct: 1200 IMSLPAQYDTVLGSKGTQLSGGQKQRIAIARAMVRNPKILLLDEATSALDFQSERVVQQA 1259
Query: 612 LQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
L + G+T I IAHR+STIQ+++ VI + + G + E GS +L+A
Sbjct: 1260 LDS-ACSGRTCIVIAHRLSTIQNAN-VICVIQAGKIVEQGSHSQLLA 1304
Score = 206 bits (525), Expect = 8e-53
Identities = 158/560 (28%), Positives = 262/560 (46%), Gaps = 44/560 (7%)
Query: 122 GKLLDIARXXXXXXXXXXXTMIFGLTST--QFYTALGGVFVVGALANVGRIVILKVTGER 179
GK+L A ++ FG+ T GV+ V A R+ + +
Sbjct: 103 GKILTNASYEENMQELRKDSVSFGILMTLNTLLMLFSGVYYVDAF---NRLAL------K 153
Query: 180 LVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFV 239
L R+R KA L Q+ + D + + R++ + + + +NL + +
Sbjct: 154 LTVRMRREFFKATLRQEIGWHDMAKDQNFAVRITDNMEKIRSGIAENLGHYVEIMCDVII 213
Query: 240 GFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATK 299
+ WKL ++ P V+ L+ Q Q+S + V EE + A +
Sbjct: 214 SVVLSFIYGWKLALAIVFYIPLTLVVNSAVAHYQGKLTGQEQSSYVRASSVVEEVIGAIR 273
Query: 300 TIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALL-LTGTSMI 358
T+ A+ GE+ E RY D + LK AL +G + G + + + A+L +TG
Sbjct: 274 TVVAFGGERSESLRY-DSL-------LKPALKAGKWKGAFSGLSDTVMKAMLFITGAGSF 325
Query: 359 KTG---LMTVGDLS----------SFMMYAVXXXXXXXXXXXXXXELMK----GAGAAAR 401
G ++ D S + +M + ++ G+A+
Sbjct: 326 WYGANLILYYRDPSIPIDEREYTPAVVMIVISGIIVSANQISRTSPFLETFAMARGSASA 385
Query: 402 VFELNDRKPLIHPT--IGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHV 459
+ ++ DR LI P GK ++ F V F YP R + LN V G+ V
Sbjct: 386 ILDVIDRTSLIDPLSKAGKILNYGLKGAVEFRDVFFRYPAREDVIVLRGLNVVVEEGQTV 445
Query: 460 CIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGT 519
+VGPSG GKST LL R+YD G++ L +++R +N++ R + VV QEP+LF G+
Sbjct: 446 ALVGPSGCGKSTCIQLLQRFYDPVFGQVLLDGEDVRKYNIKWLRSNIAVVGQEPVLFQGS 505
Query: 520 ILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIA 579
I +NI + P+ + + A AN F+ G T + +G QLSGGQ+QRIA
Sbjct: 506 IGENIRHGKPEA---TQKEVEDAAKAANAHDFIIALHKGYDTDISEKGVQLSGGQRQRIA 562
Query: 580 LARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVI 639
+ARA + P IL+LDEATSALD SE++V Q+ ++ +G+TT+ ++HR+S I+H+ R++
Sbjct: 563 IARALIQQPKILLLDEATSALDYHSEKLV-QAALDKACKGRTTLVVSHRLSAIRHAHRIV 621
Query: 640 VLNRHGTVAETGSFDKLIAI 659
+ +G E G+ ++L+ +
Sbjct: 622 YI-ENGKAVEQGTHEELMKL 640
>At2g39480 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1407
Score = 227 bits (579), Expect = 4e-59
Identities = 161/539 (29%), Positives = 265/539 (48%), Gaps = 36/539 (6%)
Query: 143 IFGLTSTQFYTALGG---------------VFVVGALANVGRIVILKVTGERLVARLRTR 187
+ L T +YT+ G + +V +AN + + GE++ R+R
Sbjct: 855 VIALVVTTYYTSKGSHLREEVDKWCLIIACMGIVTVVANFLQHFYFGIMGEKMTERVRRM 914
Query: 188 TMKAALEQDATFLDH--NRVGDLISRLSSDAGIVSKSVTQNLS----DGTRAVIQGFVGF 241
A L + + D N L RL++DA V + + LS D ++ +G
Sbjct: 915 MFSAMLRNEVGWYDEEENSPDTLSMRLANDATFVRAAFSNRLSIFIQDSFAVIVAILIGL 974
Query: 242 GMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTI 301
+ W+L V + P L + A+ + S+ +Q + + V E+ + T+
Sbjct: 975 ----LLGWRLALVALATLPVLTLSAIAQKLWLAGFSKGIQEMHRKASLVLEDAVRNIYTV 1030
Query: 302 QAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLL--TGTSMIK 359
A+C K + Y +++++ + G FG + F+ A ALLL T S+ +
Sbjct: 1031 VAFCAGNKVMELYRLQLQRILRQSFFHGMAIGFAFGFSQFL-LFACNALLLWYTALSVDR 1089
Query: 360 TGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHP--TIG 417
+ L+ +M+++ ++K + A VFE+ DR P I P T
Sbjct: 1090 RYMKLSTALTEYMVFSFATFALVEPFGLAPY-ILKRRRSLASVFEIIDRVPTIEPDDTSA 1148
Query: 418 KDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLL 477
P + SI ++ F YPTRP+ + + + V G+ V +VG SG GKST+ SL+
Sbjct: 1149 LSPPNVYG-SIELKNIDFCYPTRPEVLVLSNFSLKVNGGQTVAVVGVSGSGKSTIISLIE 1207
Query: 478 RYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDET 537
RYYD +G++ L +++ +NLR R +G++QQEP++FS TI +NI YA E
Sbjct: 1208 RYYDPVAGQVLLDGRDLKSYNLRWLRSHMGLIQQEPIIFSTTIRENIIYARHNA---SEA 1264
Query: 538 RISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEAT 597
+ A AN F+++ P G T +G RG +L+ GQKQRIA+AR L + IL++DEA+
Sbjct: 1265 EMKEAARIANAHHFISSLPHGYDTHIGMRGVELTQGQKQRIAIARVVLKNAPILLIDEAS 1324
Query: 598 SALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
S+++S+S VV ++L KTTI IAHRV+ ++H ++VLN G + E G+ D L
Sbjct: 1325 SSIESESSRVVQEALDTLIMGNKTTILIAHRVAMMRHVDNIVVLN-GGKIVEEGTHDCL 1382
Score = 195 bits (496), Expect = 2e-49
Identities = 142/516 (27%), Positives = 256/516 (49%), Gaps = 19/516 (3%)
Query: 146 LTSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLD-HNR 204
L+ T Y A GGVF+ G + + +TGER A +R++ ++ L QD +F D +
Sbjct: 135 LSLTIVYIA-GGVFISGWI----EVSCWILTGERQTAVIRSKYVQVLLNQDMSFFDTYGN 189
Query: 205 VGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFIS-WKLTCVMMLLAPPLG 263
GD++S++ SD ++ ++++ + + + F+ ++ F++ W++ + + P +
Sbjct: 190 NGDIVSQVLSDVLLIQSALSEKVGNYIHNMAT-FISGLIIGFVNCWEIALITLATGPFIV 248
Query: 264 VMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFH 323
+ + L+ +Q + E ++E+ +S +T+ A+ E + YA ++
Sbjct: 249 AAGGISNIFLHRLAENIQDAYAEAASIAEQAVSYVRTLYAFTNETLAKYSYATSLQATLR 308
Query: 324 VGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXX 383
G+ +L G G T + + L G + G++ + + +
Sbjct: 309 YGILISLVQGLGLGFTYGLAICSCAMQLWIGRFFVIHHRANGGEIITALFAVILSGLGLN 368
Query: 384 XXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLE--NKSIHFNHVKFSYPTRP 441
+G AA R+FE+ R ++ + L +I F +V FSY +RP
Sbjct: 369 QAATNFYSFDQGRIAAYRLFEMISRSS---SGTNQEGIILSAVQGNIEFRNVYFSYLSRP 425
Query: 442 QHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRK 501
+ I TV + V +VG +G GKS++ L+ R+YD GE+ L +NI++ L
Sbjct: 426 EIPILSGFYLTVPAKKAVALVGRNGSGKSSIIPLMERFYDPTLGEVLLDGENIKNLKLEW 485
Query: 502 YRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQT 561
R +G+V QEP L S +I +NI Y L +I A +A+ F+++ G +T
Sbjct: 486 LRSQIGLVTQEPALLSLSIRENIAYGRDATL----DQIEEAAKKAHAHTFISSLEKGYET 541
Query: 562 TVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKT 621
VG G L+ QK ++++ARA LLDP+IL+LDE T LD ++E VV ++L G++
Sbjct: 542 QVGKTGLTLTEEQKIKLSIARAVLLDPTILLLDEVTGGLDFEAERVVQEALDLLML-GRS 600
Query: 622 TISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
TI IA R+S I+++ + V+ G + E G+ D+LI
Sbjct: 601 TIIIARRLSLIRNADYIAVM-EEGQLLEMGTHDELI 635
>At3g55320 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1408
Score = 224 bits (571), Expect = 4e-58
Identities = 159/540 (29%), Positives = 261/540 (47%), Gaps = 34/540 (6%)
Query: 143 IFGLTSTQFYTALGG---------------VFVVGALANVGRIVILKVTGERLVARLRTR 187
+ L T++Y + GG + +V +AN + + GE++ R+R
Sbjct: 856 VIALVVTEYYKSKGGHLREEVDKWCLIIACMGIVTVVANFLQHFYFGIMGEKMTERVRRM 915
Query: 188 TMKAALEQDATFLD--HNRVGDLISRLSSDAGIVSKSVTQNLS----DGTRAVIQGFVGF 241
A L + + D N L RL++DA V + + LS D ++ +G
Sbjct: 916 MFSAMLRNEVGWFDDEENSPDTLSMRLANDATFVRAAFSNRLSIFIQDSFAVIVALLIGL 975
Query: 242 GMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTI 301
+ W+L V + P L + A+ + S+ +Q + + V E+ + T+
Sbjct: 976 ----LLGWRLALVALATLPILTLSAIAQKLWLAGFSKGIQEMHRKASLVLEDAVRNIYTV 1031
Query: 302 QAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSM-IKT 360
A+C K + Y +++++ + G FG + F+ A ALLL T++ +
Sbjct: 1032 VAFCAGNKVMELYRMQLQRILRQSYLHGMAIGFAFGFSQFL-LFACNALLLWCTALSVNR 1090
Query: 361 GLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGK-- 418
G M + + M ++K + VFE+ DR P I P
Sbjct: 1091 GYMKLSTAITEYMVFSFATFALVEPFGLAPYILKRRKSLISVFEIVDRVPTIEPDDNSAL 1150
Query: 419 DPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLR 478
P + SI +V F YPTRP+ + + + + G+ V +VG SG GKST+ SL+ R
Sbjct: 1151 KPPNVYG-SIELKNVDFCYPTRPEILVLSNFSLKISGGQTVAVVGVSGSGKSTIISLVER 1209
Query: 479 YYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETR 538
YYD +G++ L +++ +NLR R +G+VQQEP++FS TI +NI YA E
Sbjct: 1210 YYDPVAGQVLLDGRDLKLYNLRWLRSHMGLVQQEPIIFSTTIRENIIYARHNA---SEAE 1266
Query: 539 ISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATS 598
+ A AN F+++ P G T +G RG +L+ GQKQRIA+AR L + I+++DEA+S
Sbjct: 1267 MKEAARIANAHHFISSLPHGYDTHIGMRGVELTPGQKQRIAIARVVLKNAPIILIDEASS 1326
Query: 599 ALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
+++S+S VV ++L KTTI IAHR + ++H ++VLN G + E G+ D L A
Sbjct: 1327 SIESESSRVVQEALDTLIMGNKTTILIAHRAAMMRHVDNIVVLN-GGRIVEEGTHDSLAA 1385
Score = 199 bits (506), Expect = 1e-50
Identities = 140/514 (27%), Positives = 257/514 (49%), Gaps = 15/514 (2%)
Query: 146 LTSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLD-HNR 204
L+ T Y A GGVF+ G + + +TGER A +R++ ++ L QD +F D +
Sbjct: 137 LSLTIVYIA-GGVFISGWI----EVSCWILTGERQTAVIRSKYVQVLLNQDMSFFDTYGN 191
Query: 205 VGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFIS-WKLTCVMMLLAPPLG 263
GD++S++ SD ++ ++++ + + + F+ ++ F++ W++ + + P +
Sbjct: 192 NGDIVSQVLSDVLLIQSALSEKVGNYIHNMAT-FISGLVIGFVNCWEIALITLATGPFIV 250
Query: 264 VMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFH 323
+ + L+ +Q + E ++E+ +S +T+ A+ E + YA ++
Sbjct: 251 AAGGISNIFLHRLAENIQDAYAEAAGIAEQAISYIRTLYAFTNETLAKYSYATSLQATLR 310
Query: 324 VGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXX 383
G+ +L G G T + + L G + G G++ + + +
Sbjct: 311 YGILISLVQGLGLGFTYGLAICSCALQLWIGRFFVHNGRANGGEIIAALFAVILSGLGLN 370
Query: 384 XXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQH 443
+G AA R+FE+ R + G +++ +I F +V FSY +RP+
Sbjct: 371 QAATNFYSFDQGRIAAYRLFEMITRSSSVANQEGAVLASVQG-NIEFRNVYFSYLSRPEI 429
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYR 503
I TV + V +VG +G GKS++ L+ R+YD GE+ L +NI++ L R
Sbjct: 430 PILSGFYLTVPAKKAVALVGRNGSGKSSIIPLMERFYDPTLGEVLLDGENIKNLKLEWLR 489
Query: 504 RLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTV 563
+G+V QEP L S +I +NI Y L +I A A+ F+++ G +T V
Sbjct: 490 SQIGLVTQEPALLSLSIRENIAYGRDATL----DQIEEAAKNAHAHTFISSLEKGYETQV 545
Query: 564 GPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTI 623
G G ++ QK ++++ARA LL+P+IL+LDE T LD ++E +V ++L G++TI
Sbjct: 546 GRAGLAMTEEQKIKLSIARAVLLNPTILLLDEVTGGLDFEAERIVQEALDLLML-GRSTI 604
Query: 624 SIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
IA R+S I+++ + V+ G + E G+ D+LI
Sbjct: 605 IIARRLSLIKNADYIAVM-EEGQLVEMGTHDELI 637
>Hs9961248 [U] KOG0058 Peptide exporter ABC superfamily
Length = 653
Score = 224 bits (570), Expect = 5e-58
Identities = 137/431 (31%), Positives = 222/431 (50%), Gaps = 4/431 (0%)
Query: 176 TGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVI 235
T R+ R+R + + L QD F + G+L SRLSSD ++S + N + R+++
Sbjct: 217 TMSRINLRIREQLFSSLLRQDLGFFQETKTGELNSRLSSDTTLMSNWLPLNANVLLRSLV 276
Query: 236 QGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQL 295
+ +G M IS +LT + +L P VY R + + R++Q +V +V E +
Sbjct: 277 KVVGLYGFMLSISPRLTLLSLLHMPFTIAAEKVYNTRHQEVLREIQDAVARAGQVVREAV 336
Query: 296 SATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGT 355
+T++++ E+ E+ RY + + + + + L + + + + +L G
Sbjct: 337 GGLQTVRSFGAEEHEVCRYKEALEQCRQLYWRRDLERALYLLIRRVLHLGVQMLMLSCGL 396
Query: 356 SMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPT 415
++ G +T G L SFM+Y +++ GAA +VF DR+P +
Sbjct: 397 QQMQDGELTQGSLLSFMIYQESVGSYVQTLVYIYGDMLSNVGAAEKVFSYMDRQPNLPSP 456
Query: 416 IGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASL 475
P TL+ + F V F+YP RP + + L FT+RPGE +VGP+G GKSTVA+L
Sbjct: 457 GTLAPTTLQGV-VKFQDVSFAYPNRPDRPVLKGLTFTLRPGEVTALVGPNGSGKSTVAAL 515
Query: 476 LLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVND 535
L Y G++ L I + + V QEP+LFSG++ +NI Y + +
Sbjct: 516 LQNLYQPTGGQVLLDEKPISQYEHCYLHSQVVSVGQEPVLFSGSVRNNIAYGLQS---CE 572
Query: 536 ETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDE 595
+ ++ A A+ F+ G+ T VG +G+QL+ GQKQR+A+ARA + DP +LILDE
Sbjct: 573 DDKVMAAAQAAHADDFIQEMEHGIYTDVGEKGSQLAAGQKQRLAIARALVRDPRVLILDE 632
Query: 596 ATSALDSQSEE 606
ATSALD Q E+
Sbjct: 633 ATSALDVQCEQ 643
>CE24868 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1239
Score = 215 bits (548), Expect = 2e-55
Identities = 156/525 (29%), Positives = 265/525 (49%), Gaps = 35/525 (6%)
Query: 149 TQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDL 208
T Y LG ++ LA + + I + T R++ +R + A L QDA +LD + G +
Sbjct: 121 TLIYAGLGFGVIILVLALIQGVCIQRGTS-RILDSIRKEFLGAVLRQDANWLDKHSSGSI 179
Query: 209 ISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMM----SFISWKLTCVMMLLAPPLGV 264
+L+ + ++S L + +++GF F +FI+W+LT + + P
Sbjct: 180 TCQLNENIEVIS----DGLGNKCCMLVRGFAMFTSSIIACAFINWQLTFITFTMGPVSAF 235
Query: 265 MALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEK---KEIHRYADEVRKV 321
+ + K + +L + + + EE + +T+Q+ G+ ++++ ++++K
Sbjct: 236 VLHLLTKVNEVSNEELMSLSAQSHAIIEESILNVRTVQSCNGQNFMITKLNQVNEKIKKF 295
Query: 322 FHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMI-------KTGLMTVGDLSSFMMY 374
++ K +G F G+ FV +TG S+ + GD+ +
Sbjct: 296 YN---KSTFWAGFFDGLALFV------IYFITGISLFFGCRLYFNQEIGKAGDVILIVNT 346
Query: 375 AVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVK 434
L + A + +++ + P G+ ++ +I F V+
Sbjct: 347 ICVTGYFLGLLGPHMSSLQQAATSFLLLYKTIESAPKSEGKEGEIKISSTRGNIEFRDVR 406
Query: 435 FSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNI 494
F Y TR + + + L+ V PG+ V +VG SG GKST LL + Y GEI + NI
Sbjct: 407 FKYFTR-DNEVLQGLSLQVLPGQTVALVGTSGCGKSTSIGLLTKLYRASEGEILIDGKNI 465
Query: 495 RDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLAN 554
+ + R+ +G+VQQEP LF GTI++NI V++ET I A AN + F+
Sbjct: 466 DMLDAKSLRQQIGIVQQEPKLFDGTIMENIKLG---RNVDEET-IKTAADIANASSFIEK 521
Query: 555 FPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQ 614
+G +T +GP G QLSGGQKQRI +ARA + PSIL+LDEATSALDS +E +V ++L
Sbjct: 522 LENGYETRLGPGGVQLSGGQKQRICIARALVTSPSILLLDEATSALDSHNEHIVNKAL-T 580
Query: 615 RSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAI 659
+++ G+TTI IAHR+S+++ R+ VL++ G E G+ D+LI +
Sbjct: 581 KASEGRTTIIIAHRLSSLKSVDRIYVLDQ-GKTKEIGTHDELILL 624
Score = 190 bits (483), Expect = 6e-48
Identities = 108/279 (38%), Positives = 172/279 (60%), Gaps = 8/279 (2%)
Query: 391 ELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLN 450
E+++G+ +A ++F D K + T G + K + + V F+YP+ P ++ E +
Sbjct: 964 EIVRGSASANQIFSFFD-KNRTNSTSGLSKPEINGK-VEVSDVTFAYPSTPHRNVCEGFS 1021
Query: 451 FTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQ 510
+ G + +VG SG GKST+ S+L R+Y +G I + +++I ++ R + VV
Sbjct: 1022 LNIPKGHSIALVGASGCGKSTIISMLERFYSAKAGRISVDDNDIDGIDVNHLRNNISVVG 1081
Query: 511 QEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQL 570
QEP+LF+ TI +NIT + + V + + +A AN F+ +FP G T VG G L
Sbjct: 1082 QEPVLFNATIRENITIGIDEVSVEE---VQKACKAANAAGFIESFPLGYDTIVGEGGASL 1138
Query: 571 SGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVS 630
SGGQKQRIA+ARA + P IL+LDEATSALD+QSEE+V ++L+ + G+T+I +AHR+S
Sbjct: 1139 SGGQKQRIAIARAIIRKPKILLLDEATSALDTQSEEIVQKALRS-ATTGRTSIIVAHRLS 1197
Query: 631 TIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLS 669
T+QH + ++R G VAE G+ +L+A+ DS +L++
Sbjct: 1198 TVQHCDTIYYISR-GAVAEYGTHAELVAM-DSKYARLVA 1234
>At5g03910 [U] KOG0058 Peptide exporter ABC superfamily
Length = 634
Score = 204 bits (520), Expect = 3e-52
Identities = 152/477 (31%), Positives = 245/477 (50%), Gaps = 29/477 (6%)
Query: 181 VARLRTRTMKAALEQDATFLDHNR---VGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQG 237
V ++R + LE++ F + GD+ R++++A V+ ++ L+ + IQ
Sbjct: 147 VYKIRVFAYRRVLERELEFFEGGNGISSGDIAYRITAEASEVADTIYALLNTVVPSAIQI 206
Query: 238 FVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSA 297
V M S LT V ++ P + ++ G R+R +SR+ Q + +L+ E L A
Sbjct: 207 SVMTAHMIVASPALTLVSAMVIPSVALLIAYLGDRLRKISRKAQIASAQLSTYLNEVLPA 266
Query: 298 TKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTG--FVGNVALL---ALLL 352
++A E E R+ R K+ + ++G++++ A++L
Sbjct: 267 ILFVKANNAEISESVRFQRFARADLDERFKKKKMKSLIPQIVQVMYLGSLSIFCVGAVIL 326
Query: 353 TGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELN--DRKP 410
G+S+ + +++ +F++ V EL +G A R+F+L + K
Sbjct: 327 AGSSLSSSAIVSFVASLAFLIDPVQDLGKAYN------ELKQGEPAIERLFDLTSLESKV 380
Query: 411 LIHPTIGKDPVTLENKS--IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGG 468
+ P + + LE + + + F Y + + LN ++ GE V +VGPSGGG
Sbjct: 381 IERP----EAIQLEKVAGEVELCDISFKYDEN-MLPVLDGLNLHIKAGETVALVGPSGGG 435
Query: 469 KSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAV 528
K+T+ LLLR Y+ SG I + +I+D L R+ +G+V Q+ LFSGTI DNI Y
Sbjct: 436 KTTLIKLLLRLYEPSSGSIIIDKIDIKDIKLESLRKHVGLVSQDTTLFSGTIADNIGY-- 493
Query: 529 PQELVN--DETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLL 586
++L D R+ A AN +F+ N P+G T VGPRG+ LSGGQKQR+A+ARA
Sbjct: 494 -RDLTTGIDMKRVELAAKTANADEFIRNLPEGYNTGVGPRGSSLSGGQKQRLAIARALYQ 552
Query: 587 DPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNR 643
SILILDEATSALDS SE +V ++L +R + T I IAHR+ T+ + RV ++ R
Sbjct: 553 KSSILILDEATSALDSLSELLVREAL-ERVMQDHTVIVIAHRLETVMMAQRVFLVER 608
>SPCC737.09c [P] KOG0056 Heavy metal exporter HMT1 ABC superfamily
Length = 505
Score = 204 bits (518), Expect = 5e-52
Identities = 130/391 (33%), Positives = 205/391 (52%), Gaps = 9/391 (2%)
Query: 278 RQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFG 337
R++ S E V + + +T++ + + E RY V ++ ++ L S F
Sbjct: 109 RKMVNSWRESYAVQNDAIMNFETVKNFDADDFENERYGHAV-DIYLKQERKVLFSLNFLN 167
Query: 338 VT-GFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGA 396
+ G + +L L + G TVGD + Y + L
Sbjct: 168 IVQGGIFTFSLAIACLLSAYRVTFGFNTVGDFVILLTYMIQLQQPLNFFGTLYRSLQNSI 227
Query: 397 GAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPG 456
R+ E+ + KP + + + + F+HV F+Y P+ + D+NF +PG
Sbjct: 228 IDTERLLEIFEEKPTVVEKPNAPDLKVTQGKVIFSHVSFAYD--PRKPVLSDINFVAQPG 285
Query: 457 EHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLF 516
+ + +VG SGGGKST+ +LLR++D+ SG I + + +IR+ L R +GVV Q+ LF
Sbjct: 286 KVIALVGESGGGKSTIMRILLRFFDVNSGSITIDDQDIRNVTLSSLRSSIGVVPQDSTLF 345
Query: 517 SGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQ 576
+ TIL NI YA P N+E I A A + FPDG + VG RG +LSGG+KQ
Sbjct: 346 NDTILYNIKYAKP-SATNEE--IYAAAKAAQIHDRILQFPDGYNSRVGERGLKLSGGEKQ 402
Query: 577 RIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSS 636
R+A+ARA L DPSI++LDEATSALD+ +E + Q+ R A G+T I IAHR+STI ++
Sbjct: 403 RVAVARAILKDPSIILLDEATSALDTNTERQI-QAALNRLASGRTAIVIAHRLSTITNAD 461
Query: 637 RVIVLNRHGTVAETGSFDKLIAIPDSSLNKL 667
++ ++ +G + ETG+ ++LI + K+
Sbjct: 462 LILCIS-NGRIVETGTHEELIKRDGGAYKKM 491
>YKL209c [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1290
Score = 198 bits (503), Expect = 3e-50
Identities = 139/509 (27%), Positives = 244/509 (47%), Gaps = 29/509 (5%)
Query: 177 GERLVARLRTRTMKAALEQ---------DATFLDHNRVGDLISRLSSDAGIVSKSVTQNL 227
GER R+R++ ++A LE+ + D ++ + L S + S QNL
Sbjct: 100 GERQGFRIRSQILEAYLEEKPMEWYDNNEKLLGDFTQINRCVEELRSSSAEASAITFQNL 159
Query: 228 SDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGEL 287
I +G + SW LT +++ +P + A+V+ + I S + + +
Sbjct: 160 -----VAICALLGTSF--YYSWSLTLIILCSSPIITFFAVVFSRMIHVYSEKENSETSKA 212
Query: 288 TKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVAL 347
++ ++A + ++ YC ++ E ++ + + +K A G+ F+
Sbjct: 213 AQLLTWSMNAAQLVRLYCTQRLERKKFKEIILNCNTFFIKSCFFVAANAGILRFLTLTMF 272
Query: 348 LALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFEL-- 405
+ G++MIK G + + D+ + + L KG A ++ L
Sbjct: 273 VQGFWFGSAMIKKGKLNINDVITCFHSCIMLGSTLNNTLHQIVVLQKGGVAMEKIMTLLK 332
Query: 406 --NDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVG 463
+ R PL + P+ + F +V FSYP+RP + ++++ G+ IVG
Sbjct: 333 DGSKRNPLNKTVAHQFPLDYATSDLTFANVSFSYPSRPSEAVLKNVSLNFSAGQFTFIVG 392
Query: 464 PSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDN 523
SG GKST+++LLLR+YD +G I + NI+ + + + VV+Q LF+ T+ N
Sbjct: 393 KSGSGKSTLSNLLLRFYDGYNGSISINGHNIQTIDQKLLIENITVVEQRCTLFNDTLRKN 452
Query: 524 ITYAVPQELVN-----DETR--ISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQ 576
I + N +E R I A A +F+ + PDGL+T +G G LSGGQ+Q
Sbjct: 453 ILLGSTDSVRNADCSTNENRHLIKDACQMALLDRFILDLPDGLETLIGTGGVTLSGGQQQ 512
Query: 577 RIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSS 636
R+A+ARAF+ D IL LDEA SALD ++ +++ + +GKTTI + H +S I+ S
Sbjct: 513 RVAIARAFIRDTPILFLDEAVSALDIVHRNLLMKAI-RHWRKGKTTIILTHELSQIE-SD 570
Query: 637 RVIVLNRHGTVAETGSFDKLIAIPDSSLN 665
+ L + G V E+G+ +L+A P ++ +
Sbjct: 571 DYLYLMKEGEVVESGTQSELLADPTTTFS 599
Score = 183 bits (465), Expect = 7e-46
Identities = 138/530 (26%), Positives = 246/530 (46%), Gaps = 24/530 (4%)
Query: 145 GLTSTQFYTALGGVFVVGALA-----NVGRIVILKVTGERLVARLRTRTMKAALEQDATF 199
G T + Y A + V+G A N + +L E V LR M+ ++ +
Sbjct: 751 GKTGSSHYLAKWSLLVLGVAAADGIFNFAKGFLLDCCSEYWVMDLRNEVMEKLTRKNMDW 810
Query: 200 L--DHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMML 257
++N+ ++ + + +D + V++ LS T V +G WKL+ V +
Sbjct: 811 FSGENNKASEISALVLNDLRDLRSLVSEFLSAMTSFVTVSTIGLIWALVSGWKLSLVCIS 870
Query: 258 LAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADE 317
+ P + + + +YG ++ +TSV +L + ++ KTI+ E Y D
Sbjct: 871 MFPLIIIFSAIYGGILQKCETDYKTSVAQLENCLYQIVTNIKTIKCLQAEFHFQLTYHDL 930
Query: 318 VRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVX 377
K+ + K A+ +G +T + + G ++ T ++ + +
Sbjct: 931 KIKMQQIASKRAIATGFGISMTNMIVMCIQAIIYYYGLKLVMIHEYTSKEMFTTFTLLLF 990
Query: 378 XXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHP-------TIGKDPVTLENKS--- 427
++ +G AA+ ++ + D K T+G T K
Sbjct: 991 TIMSCTSLVSQIPDISRGQRAASWIYRILDEKHNTLEVENNNARTVGIAGHTYHGKEKKP 1050
Query: 428 -IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGE 486
+ ++ F+YP+ P +++++NF + G+ + I+G SG GKST+ LL + Y+ G+
Sbjct: 1051 IVSIQNLTFAYPSAPTAFVYKNMNFDMFCGQTLGIIGESGTGKSTLVLLLTKLYNCEVGK 1110
Query: 487 IKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQA 546
IK+ ++ D+NL R+ + VV+Q+P+LF+GTI DN+TY + E++ E + A+
Sbjct: 1111 IKIDGTDVNDWNLTSLRKEISVVEQKPLLFNGTIRDNLTYGLQDEIL--EIEMYDALKYV 1168
Query: 547 NCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEE 606
F+ + P GL T + T LSGGQ QR+ +ARA L ILILDE TSALDS S
Sbjct: 1169 GIHDFVISSPQGLDTRIDT--TLLSGGQAQRLCIARALLRKSKILILDECTSALDSVSSS 1226
Query: 607 VVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
++ + ++ T+ I H ++ + + VL + G V E G+FD L
Sbjct: 1227 II-NEIVKKGPPALLTMVITHSEQMMRSCNSIAVL-KDGKVVERGNFDTL 1274
>CE04268 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1283
Score = 196 bits (498), Expect = 1e-49
Identities = 148/512 (28%), Positives = 244/512 (46%), Gaps = 11/512 (2%)
Query: 152 YTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNR--VGDLI 209
YTAL + V +GRI I + G +R + L A + D R G L+
Sbjct: 764 YTAL--IIVKTIFEALGRIFIA-LYGHGFCKFMRNEMFRKVLRHGAAYFDEERNSPGRLV 820
Query: 210 SRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVY 269
++ +++ +++ + Q L V+ +I+WK+ + P V+ ++
Sbjct: 821 HKVINESSTLNEIMEQKLDMLIPGVVCSLFSIVCALWINWKMALLCSFQFPAYFVIRILQ 880
Query: 270 GKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEA 329
+ RQ+ + ++ L+ TI+AY + + + D ++ V K++
Sbjct: 881 IREGTKRQRQMVDEEKKAANLASVVLANMSTIKAYNLQSHFYNVFCDALKPVSQCMQKQS 940
Query: 330 LTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXX 389
L S F + + L G M+ ++V D ++
Sbjct: 941 LISALVFACQYSFTYILIAITLHFGKVMMLANEISVFDYMRVVLLTQFGANFFSQLIASV 1000
Query: 390 XELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENK-SIHFNHVKFSYPTRPQHHIFED 448
+ K AA V + P+ + ++ + + + ++ V F YP+RP + +
Sbjct: 1001 SDFTKAQIAAENVMRVIREPPVDMDNLSEEGLRPKLEGNLCLKDVSFRYPSRPIVPVLTN 1060
Query: 449 LNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGV 508
LN VR GE + +VGPSG GKS+V SL R Y+ G + + NI+ N RR +
Sbjct: 1061 LNLKVRGGESIALVGPSGSGKSSVISLFQRMYNATDGVVIIDKYNIKSINPAYLRRCIVQ 1120
Query: 509 VQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGT 568
V QEP LFS TI +NI + + + + ++ A A+ F+ + P G T VG G
Sbjct: 1121 VGQEPDLFSFTIKENIAFGMMESEATID-KVIEAAKIADIHNFITSLPQGYDTEVGEFGA 1179
Query: 569 QLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQ--QRSARGK-TTISI 625
QLSGGQKQRIA+ARA + P++L+LDEATSALDS SE V + + +RS + + T I I
Sbjct: 1180 QLSGGQKQRIAIARAIIRKPTVLLLDEATSALDSASEREVQNAFERVKRSTKTQCTCIQI 1239
Query: 626 AHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
AHR+STI++ ++ V+ HG +AE GS ++LI
Sbjct: 1240 AHRLSTIRNVDKIYVI-VHGEIAEEGSHEQLI 1270
Score = 196 bits (497), Expect = 1e-49
Identities = 112/244 (45%), Positives = 152/244 (61%), Gaps = 11/244 (4%)
Query: 427 SIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGE 486
++HF + FSYP+R + + ++F V GE + IVG SG GKST+ +LLLR+YD G
Sbjct: 349 ALHFRDIHFSYPSRKETEVLRGISFKVEAGEKIAIVGSSGSGKSTLTALLLRFYDPTKGA 408
Query: 487 IKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYA---VPQELVNDETRISRAI 543
I L +NI+ R +V QEP+LF GTI DNI Y Q+ +ND R
Sbjct: 409 ILLDGENIKTMCPDDLRGQCSLVSQEPVLFDGTISDNIRYGRLDATQQEINDAAR----- 463
Query: 544 GQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQ 603
+ KF+ + PDG+QT VG RG QLSGGQKQR+A+ARA + P +LI DEATSALD+
Sbjct: 464 -KVGAWKFINSLPDGMQTRVGERGHQLSGGQKQRVAIARAVIRKPIVLIFDEATSALDNI 522
Query: 604 SEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSS 663
EE V ++ S G TTI+IAHR+STI++S R+IVL+ G + E G D+LIA +
Sbjct: 523 HEEEVNAAIDLAS-EGLTTITIAHRLSTIKNSDRIIVLH-EGKIVEEGVPDELIADANGI 580
Query: 664 LNKL 667
+K+
Sbjct: 581 FHKM 584
>Hs9955963 [P] KOG0056 Heavy metal exporter HMT1 ABC superfamily
Length = 842
Score = 186 bits (473), Expect = 8e-47
Identities = 134/446 (30%), Positives = 216/446 (48%), Gaps = 10/446 (2%)
Query: 213 SSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKR 272
SS G++S V N+ +I G + F M F +W V + ++ L + +V R
Sbjct: 378 SSVTGLLSYLVF-NVIPTLADIIIGIIYFSMF-FNAWFGLIVFLCMSLYLTLTIVVTEWR 435
Query: 273 IRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTS 332
+ R + T + + L +T++ Y E E+ RY + + K + K + +
Sbjct: 436 TK-FRRAMNTQENATRARAVDSLLNFETVKYYNAESYEVERYREAIIKYQGLEWKSSASL 494
Query: 333 GAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXEL 392
V + LLA L + + VGD F Y + +
Sbjct: 495 VLLNQTQNLVIGLGLLAGSLLCAYFVTEQKLQVGDYVLFGTYIIQLYMPLNWFGTYYRMI 554
Query: 393 MKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFT 452
+F+L + + G P+ + I F +V FSY + +D++FT
Sbjct: 555 QTNFIDMENMFDLLKEETEVKDLPGAGPLRFQKGRIEFENVHFSYADGRE--TLQDVSFT 612
Query: 453 VRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQE 512
V PG+ + +VGPSG GKST+ LL R+YDI SG I++ +I R +GVV Q+
Sbjct: 613 VMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQDISQVTQASLRSHIGVVPQD 672
Query: 513 PMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSG 572
+LF+ TI DNI Y + + A A + FP+G +T VG RG +LSG
Sbjct: 673 TVLFNDTIADNIRYG---RVTAGNDEVEAAAQAAGIHDAIMAFPEGYRTQVGERGLKLSG 729
Query: 573 GQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTI 632
G+KQR+A+AR L P I++LDEATSALD+ +E + SL + A +TTI +AHR+ST+
Sbjct: 730 GEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVCA-NRTTIVVAHRLSTV 788
Query: 633 QHSSRVIVLNRHGTVAETGSFDKLIA 658
++ +++V+ + G + E G + L++
Sbjct: 789 VNADQILVI-KDGCIVERGRHEALLS 813
>At5g58270 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC superfamily
Length = 728
Score = 186 bits (473), Expect = 8e-47
Identities = 124/360 (34%), Positives = 187/360 (51%), Gaps = 9/360 (2%)
Query: 299 KTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGV-TGFVGNVALLALLLTGTSM 357
+T++ + E E +Y D+ K + + S AF + + AL ++ +
Sbjct: 350 ETVKYFNNEGYEAEKY-DQFLKKYEDAALQTQRSLAFLNFGQSIIFSTALSTAMVLCSQG 408
Query: 358 IKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIG 417
I G MTVGDL E ++ +F+L + K I T
Sbjct: 409 IMNGQMTVGDLVMVNGLLFQLSLPLNFLGSVYRETIQSLVDMKSMFQLLEEKSDITNTSD 468
Query: 418 KDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLL 477
P+ L+ +I F +V FSY P+ I + ++F V G+ V IVG SG GKST+ +L
Sbjct: 469 AKPLVLKGGNIEFENVHFSY--LPERKILDGISFVVPAGKSVAIVGTSGSGKSTILRMLF 526
Query: 478 RYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDET 537
R++D SG I++ +I++ L R +GVV Q+ +LF+ TI NI Y L E
Sbjct: 527 RFFDTDSGNIRIDGQDIKEVRLDSLRSSIGVVPQDTVLFNDTIFHNIHYG---RLSATEE 583
Query: 538 RISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEAT 597
+ A +A + ++NFPD T VG RG +LSGG+KQR+ALAR FL P+IL+ DEAT
Sbjct: 584 EVYEAARRAAIHETISNFPDKYSTIVGERGLKLSGGEKQRVALARTFLKSPAILLCDEAT 643
Query: 598 SALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
SALDS +E + +L + A +T+I IAHR++T ++VL +G V E G D+L+
Sbjct: 644 SALDSTTEAEILNAL-KALASNRTSIFIAHRLTTAMQCDEIVVL-ENGKVVEQGPHDELL 701
>7300071 [P] KOG0056 Heavy metal exporter HMT1 ABC superfamily
Length = 866
Score = 186 bits (473), Expect = 8e-47
Identities = 126/389 (32%), Positives = 198/389 (50%), Gaps = 16/389 (4%)
Query: 278 RQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFG 337
R++ + E S + L +T++ Y E E+ Y + + K KE S
Sbjct: 425 RRMNLADNEQRARSVDSLLNFETVKYYGAEHYEVDCYREAILKY----QKEEFLSMLTLN 480
Query: 338 VTGFVGNVALLALLLTGTSM-----IKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXEL 392
+ N+ L LL G+ + + +TVGD F Y + +
Sbjct: 481 MLNTAQNIILCLGLLAGSLLCVYLVVHHQTLTVGDFVLFSTYLMELYMPLNWFGTYYRAI 540
Query: 393 MKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFT 452
K +F+L + I G P+ I F++V F Y P+ + +++FT
Sbjct: 541 QKNFVDMENMFDLLKEEEEIVDAPGCSPLLTAGGGIEFSNVTFGYS--PEKIVLRNVSFT 598
Query: 453 VRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQE 512
V G+ V IVGPSG GKST+ LL R+YD+ +G I + NI+ + R+ +GVV Q+
Sbjct: 599 VPAGKTVAIVGPSGAGKSTIMRLLFRFYDVQTGAILIDGQNIKLVQQQSLRKAIGVVPQD 658
Query: 513 PMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSG 572
+LF+ TI NI YA +L + + A A+ + + FP+ +T VG RG +LSG
Sbjct: 659 TVLFNNTIFYNIEYA---KLGASDEAVYEAARAADIHERILGFPEKYETKVGERGLRLSG 715
Query: 573 GQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTI 632
G+KQR+A+AR L P I++LDEATSALD+ +E + Q+ R +TTI +AHR+STI
Sbjct: 716 GEKQRVAIARTLLKAPIIVLLDEATSALDTHTERNI-QAALARVCANRTTIIVAHRLSTI 774
Query: 633 QHSSRVIVLNRHGTVAETGSFDKLIAIPD 661
H+ ++VL + G++AE G ++L+ D
Sbjct: 775 IHADEILVL-QQGSIAERGRHEELVLRED 802
>At4g28620 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC superfamily
Length = 680
Score = 179 bits (455), Expect = 1e-44
Identities = 142/472 (30%), Positives = 232/472 (49%), Gaps = 34/472 (7%)
Query: 207 DLISRLSSDAGIVSKSVTQNLSDGTRAV--IQGFVGFGMMSFISWKLTCVMMLLAPPLG- 263
DL L+ D G +++ + + G+RA+ I + F +M I +++ V +LA G
Sbjct: 203 DLRYHLNRDTGALNRIIDR----GSRAINTILSAMVFNIMPTIL-EISMVSCILAYKFGA 257
Query: 264 ----VMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSAT----------KTIQAYCGEKK 309
+ L G I Q + ++E + A+ +T++ + E
Sbjct: 258 VYALITCLSVGSYIAFTLAMTQWRIKIRKAMNEAENDASTRAIDSLINYETVKYFNNEDY 317
Query: 310 EIHRYADEVRKVFHVGLKEALTSGAFFGV-TGFVGNVALLALLLTGTSMIKTGLMTVGDL 368
E +Y D++ + + ++ S A F+ + AL ++ + I G MTVGDL
Sbjct: 318 EARKY-DQLHENYEDAALQSRKSFALLNFGQSFIFSTALSTAMVLCSQGIMNGQMTVGDL 376
Query: 369 SSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFE-LNDRKPLIHPTIGKD--PVTLEN 425
+ ++G +F+ L +R + I + P+ L+
Sbjct: 377 VMVNGLLFQLSLPLYFLGVVYSDTVQGLVDMKSMFKFLEERSDIGDKDIDRKLPPLVLKG 436
Query: 426 KSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSG 485
SI F +V FSY P+ I + ++F V G+ V IVG SG GKST+ ++ R++D+ SG
Sbjct: 437 GSISFENVHFSY--LPERKILDGISFEVPAGKSVAIVGSSGSGKSTILRMIFRFFDVDSG 494
Query: 486 EIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQ 545
+K+ +I++ L R +GVV Q+ +LF+ TI NI Y L E + A +
Sbjct: 495 NVKIDGQDIKEVRLESLRSSIGVVPQDTVLFNDTIFHNIHYG---NLSATEEEVYNAARR 551
Query: 546 ANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSE 605
A + FPD T VG RG LSGG+KQR+ALARAFL P+IL+ DEATSALDS++E
Sbjct: 552 AAIHDTIMKFPDKYSTAVGERGLMLSGGEKQRVALARAFLKSPAILLCDEATSALDSKTE 611
Query: 606 EVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ ++L+ A +T I IAHR++T ++V+ + G V E G+ + L+
Sbjct: 612 AEIMKTLRS-LASNRTCIFIAHRLTTAMQCDEILVMEK-GKVVEKGTHEVLL 661
>7292113 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC superfamily
Length = 606
Score = 178 bits (452), Expect = 2e-44
Identities = 128/416 (30%), Positives = 205/416 (48%), Gaps = 14/416 (3%)
Query: 244 MSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQA 303
++F + CV + A L V + + R Q + G + + L +T++
Sbjct: 167 LAFAGVSMGCVGIYAAYTLSVTQ--WRTQFRVFMNQAENEAGNK---AVDSLINYETVKY 221
Query: 304 YCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLM 363
+ EK E Y + ++K LK + + + + AL +++ I G M
Sbjct: 222 FNNEKYEAGCYNEVLKKYEAASLKTSSSLALLNFGQNAIFSSALSLIMVLAAKEIAQGNM 281
Query: 364 TVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTL 423
TVGDL E+ + +F L + I P+ +
Sbjct: 282 TVGDLVMVNALLFQLSIPLGFLGSVYREVRQALLDMRAMFTLMNVDSSIQTAANAQPLFV 341
Query: 424 E--NKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYD 481
+ N SI F +V F Y P IF DL+FT+ G++V IVG SG GKS++ LL R+++
Sbjct: 342 DTTNSSIEFRNVSFEY--EPGKPIFRDLSFTIPAGKNVAIVGGSGSGKSSMVRLLFRFFE 399
Query: 482 IGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISR 541
SG++ +G +I +L R+++ VV Q+ +LF TI NI Y L +
Sbjct: 400 PNSGKVLIGGQDISAVDLESLRKVIAVVPQDSVLFHNTIEHNIHYG---NLSKSHAEVQN 456
Query: 542 AIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALD 601
A A+ + ++P T VG RG +LSGG+KQR+A+ARA L + ILI DEATS+LD
Sbjct: 457 AARMADLHDSIMSWPGQYSTQVGERGLKLSGGEKQRVAIARAILKNTPILIFDEATSSLD 516
Query: 602 SQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
S +E + Q+L R+ G+T+I IAHR+ST++ + ++VL +G V E G+ +L+
Sbjct: 517 SITEHNILQAL-TRATSGRTSICIAHRLSTVKDADEILVL-ENGRVGERGTHSELL 570
>At4g25450 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 280
Score = 178 bits (451), Expect = 3e-44
Identities = 95/226 (42%), Positives = 146/226 (64%), Gaps = 3/226 (1%)
Query: 433 VKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGND 492
V F+YP RP + + L+ T+ G +VG SG GKST+ LL R+Y+ G I +G +
Sbjct: 41 VHFAYPLRPDVKVLDGLSLTLNSGTVTALVGSSGAGKSTIVQLLARFYEPTQGRITVGGE 100
Query: 493 NIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFL 552
++R F+ ++ +++ +V QEP+LFS ++ +NI Y +P E V+ + I +A AN F+
Sbjct: 101 DVRMFDKSEWAKVVSIVNQEPVLFSLSVAENIAYGLPNEHVSKDD-IIKAAKAANAHDFI 159
Query: 553 ANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSL 612
+ P G T VG RG LSGGQ+QR+A+AR+ L + ILILDEATSALD+ SE +V QS
Sbjct: 160 ISLPQGYDTLVGERGGLLSGGQRQRVAIARSLLKNAPILILDEATSALDAVSERLV-QSA 218
Query: 613 QQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
R + +TT+ IAHR+ST+Q ++++ V + G + E G+ +L+A
Sbjct: 219 LNRLMKDRTTLVIAHRLSTVQSANQIAVCS-DGKIIELGTHSELVA 263
>At4g28630 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC superfamily
Length = 677
Score = 172 bits (437), Expect = 1e-42
Identities = 117/362 (32%), Positives = 182/362 (49%), Gaps = 10/362 (2%)
Query: 299 KTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMI 358
+T++ + E E +Y D + + L+ + F+ + AL ++ + I
Sbjct: 304 ETVKYFNNEDYEARKYDDLLGRYEDAALQTQKSLAFLDFGQSFIFSTALSTSMVLCSQGI 363
Query: 359 KTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGK 418
G MTVGDL E ++G +F+L + + I +
Sbjct: 364 MNGEMTVGDLVMVNGLLFQLSLPLYFLGGVYRETVQGLVDMKSLFQLLEERSDIGDKDTE 423
Query: 419 D---PVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASL 475
P+ L SI F +V FSY P+ I + ++F V G+ V IVG SG GKST+ +
Sbjct: 424 TKLPPLVLRGGSISFENVHFSY--LPERKILDGISFEVPAGKSVAIVGSSGSGKSTILRM 481
Query: 476 LLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVND 535
+ R++D SG +++ +I++ L R +GVV Q+ +LF+ TI NI Y L
Sbjct: 482 IFRFFDTDSGNVRIDGQDIKEVTLESLRSCIGVVPQDTVLFNDTIFHNIHYG---NLSAT 538
Query: 536 ETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDE 595
E + A +A + FPD T VG RG LSGG+KQR+ALARAFL P+IL+ DE
Sbjct: 539 EEEVYDAARRAVIHDTIMKFPDKYSTAVGERGLMLSGGEKQRVALARAFLKSPAILLCDE 598
Query: 596 ATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDK 655
AT+ALDS++E + ++ + A +T I IAHR++T +IV+ + G V E G+
Sbjct: 599 ATNALDSKTEAEIMKTFRS-LASNRTCIFIAHRLTTAMQCDEIIVMEK-GKVVEKGTHQV 656
Query: 656 LI 657
L+
Sbjct: 657 LL 658
>Hs4757706 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC superfamily
Length = 752
Score = 169 bits (429), Expect = 1e-41
Identities = 116/371 (31%), Positives = 186/371 (49%), Gaps = 9/371 (2%)
Query: 299 KTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMI 358
+T++ + E+ E RY ++ LK T + +V L A+++ + I
Sbjct: 341 ETVKYFNNERYEAQRYDGFLKTYETASLKSTSTLAMLNFGQSAIFSVGLTAIMVLASQGI 400
Query: 359 KTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGK 418
G +TVGDL E + +F L I +
Sbjct: 401 VAGTLTVGDLVMVNGLLFQLSLPLNFLGTVYRETRQALIDMNTLFTLLKVDTQIKDKVMA 460
Query: 419 DP--VTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL 476
P +T + ++ F++V F Y + + ++F V G+ V IVG SG GKST+ LL
Sbjct: 461 SPLQITPQTATVAFDNVHFEYIEGQK--VLSGISFEVPAGKKVAIVGGSGSGKSTIVRLL 518
Query: 477 LRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDE 536
R+Y+ G I L NI+D +L RR +GVV Q+ +LF TI N+ Y +
Sbjct: 519 FRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEV 578
Query: 537 TRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEA 596
+++ G + + P G T VG RG +LSGG+KQR+A+ARA L DP +++ DEA
Sbjct: 579 YAVAKLAGLHDA---ILRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEA 635
Query: 597 TSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
TS+LDS +EE + +++ + +T+I IAHR+ST+ + +IVL++ G VAE G+ L
Sbjct: 636 TSSLDSITEETILGAMKD-VVKHRTSIFIAHRLSTVVDADEIIVLDQ-GKVAERGTHHGL 693
Query: 657 IAIPDSSLNKL 667
+A P S +++
Sbjct: 694 LANPHSIYSEM 704
>Hs22058461 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC superfamily
Length = 753
Score = 169 bits (429), Expect = 1e-41
Identities = 116/371 (31%), Positives = 186/371 (49%), Gaps = 9/371 (2%)
Query: 299 KTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMI 358
+T++ + E+ E RY ++ LK T + +V L A+++ + I
Sbjct: 342 ETVKYFNNERYEAQRYDGFLKTYETASLKSTSTLAMLNFGQSAIFSVGLTAIMVLASQGI 401
Query: 359 KTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGK 418
G +TVGDL E + +F L I +
Sbjct: 402 VAGTLTVGDLVMVNGLLFQLSLPLNFLGTVYRETRQALIDMNTLFTLLKVDTQIKDKVMA 461
Query: 419 DP--VTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL 476
P +T + ++ F++V F Y + + ++F V G+ V IVG SG GKST+ LL
Sbjct: 462 SPLQITPQTATVAFDNVHFEYIEGQK--VLSGISFEVPAGKKVAIVGGSGSGKSTIVRLL 519
Query: 477 LRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDE 536
R+Y+ G I L NI+D +L RR +GVV Q+ +LF TI N+ Y +
Sbjct: 520 FRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEV 579
Query: 537 TRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEA 596
+++ G + + P G T VG RG +LSGG+KQR+A+ARA L DP +++ DEA
Sbjct: 580 YAVAKLAGLHDA---ILRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEA 636
Query: 597 TSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
TS+LDS +EE + +++ + +T+I IAHR+ST+ + +IVL++ G VAE G+ L
Sbjct: 637 TSSLDSITEETILGAMKD-VVKHRTSIFIAHRLSTVVDADEIIVLDQ-GKVAERGTHHGL 694
Query: 657 IAIPDSSLNKL 667
+A P S +++
Sbjct: 695 LANPHSIYSEM 705
>YMR301c [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC superfamily
Length = 690
Score = 160 bits (405), Expect = 6e-39
Identities = 103/331 (31%), Positives = 170/331 (51%), Gaps = 22/331 (6%)
Query: 346 ALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFEL 405
AL A++ G + + G +TVGDL +L + +F+L
Sbjct: 353 ALTAMMYMGCTGVIGGNLTVGDLVLINQLVFQLSVPLNFLGSVYRDLKQSLIDMETLFKL 412
Query: 406 --------NDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGE 457
N +PL+ P +T EN V F Y P I ++ +FT+ G
Sbjct: 413 RKNEVKIKNAERPLMLPENVPYDITFEN-------VTFGY--HPDRKILKNASFTIPAGW 463
Query: 458 HVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFS 517
IVG SG GKST+ L+ R+YD SG I + +I+++++ R+++GVV Q+ LF+
Sbjct: 464 KTAIVGSSGSGKSTILKLVFRFYDPESGRILINGRDIKEYDIDALRKVIGVVPQDTPLFN 523
Query: 518 GTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQR 577
TI +N+ + + + + + +A + P G T VG RG +SGG+KQR
Sbjct: 524 DTIWENVKFG---RIDATDEEVITVVEKAQLAPLIKKLPQGFDTIVGERGLMISGGEKQR 580
Query: 578 IALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARG-KTTISIAHRVSTIQHSS 636
+A+AR L + I+ DEATSALD+ +E+ + ++++ G +T++ IAHR+ TI +
Sbjct: 581 LAIARVLLKNARIMFFDEATSALDTHTEQALLRTIRDNFTSGSRTSVYIAHRLRTIADAD 640
Query: 637 RVIVLNRHGTVAETGSFDKLIAIPDSSLNKL 667
++IVL+ +G V E G +L+A+P S +L
Sbjct: 641 KIIVLD-NGRVREEGKHLELLAMPGSLYREL 670
>SPAC15A10.01 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC superfamily
Length = 624
Score = 156 bits (395), Expect = 9e-38
Identities = 106/336 (31%), Positives = 160/336 (47%), Gaps = 7/336 (2%)
Query: 278 RQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFG 337
RQ + + + + E L + ++ + E E+ RY + +K A +
Sbjct: 293 RQANAADSKASAAAIESLINYEAVKTFNNESYEMSRYEKHLSAYEKANVKVASSLAFLNS 352
Query: 338 VTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAG 397
+ + AL ++ G I T +TVGDL E+ +
Sbjct: 353 GQAIIFSTALTLMMYMGCRGIVTSNLTVGDLVMINQLVFQLSIPLNFLGSVYREMRQAFT 412
Query: 398 AAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSY-PTRPQHHIFEDLNFTVRPG 456
++F L + + L+ SI F++V FSY P RP I +F + G
Sbjct: 413 DMEQLFSLKRINIQVKEAPDARDLVLKGGSIQFDNVHFSYNPNRP---ILNGCSFNIPAG 469
Query: 457 EHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLF 516
V VG SG GKST+ LL R+YD SG+I + N + L R+ +GVV Q+ LF
Sbjct: 470 AKVAFVGASGCGKSTILRLLFRFYDTDSGKILIDNQRLDQITLNSLRKAIGVVPQDTPLF 529
Query: 517 SGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQ 576
+ TIL NI Y P + NDE I A +A + +FP+G QT VG RG +SGG+KQ
Sbjct: 530 NDTILYNIGYGNP-KASNDE--IVEAAKKAKIHDIIESFPEGYQTKVGERGLMISGGEKQ 586
Query: 577 RIALARAFLLDPSILILDEATSALDSQSEEVVAQSL 612
R+A++R L +P IL DEATSALD+ +E + +++
Sbjct: 587 RLAVSRLLLKNPEILFFDEATSALDTNTERALLRNI 622
>SPBC2G5.09c [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1035
Score = 152 bits (383), Expect = 2e-36
Identities = 128/464 (27%), Positives = 219/464 (46%), Gaps = 42/464 (9%)
Query: 208 LISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMAL 267
L++ +S ++S + + T A+I G W+L V++ ++P L + +
Sbjct: 583 LVNNISDMRNMISSLIEEVFIAFTMAII----GIAWSFATGWRLAAVLVAVSPILCLTSR 638
Query: 268 VYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLK 327
++ + R Q V T + + + TI+ Y + + +RK +
Sbjct: 639 MFSYIYVSTERMCQDVVISTTSILHKTIVNLDTIKGYSVLSFFRENHKNSLRKSW----- 693
Query: 328 EALTSGAFFGVTGFVGNVALL----ALLLTGTSM-IKTGLMTVGDLSSFMMYAVXXXXXX 382
EA AF+ GF N +LL ALL +S+ I TV + + A
Sbjct: 694 EAFKRRAFWTSLGFAINNSLLYFVRALLFYCSSIFISKEFYTVEQMVQVLSLATFTLLMA 753
Query: 383 XXXXXXXXELMKGAGAAARVFELNDRKP--------LIHPTIGKDPVTLENKSIHFNHVK 434
+ A +RV +L+ KP L P +GK I F+ V
Sbjct: 754 STCIMSLPNVSASRIATSRVLKLSSLKPGNLHKSGYLKFPLVGK---------IEFDGVS 804
Query: 435 FSYPTRPQHHI-FEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDN 493
F+YP ++H+ +++ ++ E V IVG SG GKST+ LL + Y S +I +
Sbjct: 805 FAYPDSERNHLALNNVSLSIEAREKVAIVGISGSGKSTLVELLRKTYP--SEDIYIDGYP 862
Query: 494 IRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLA 553
+ + + + + +V Q+P L TIL+++ Y V +++ + A+ + T+ +
Sbjct: 863 LTNIDTNWLLKKVAIVDQKPHLLGSTILESLLYGVDRDI----NSVMDALDKTYMTEVIQ 918
Query: 554 NFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQ 613
N P+GL T + SGGQ QR+A ARA L +P +LILDE TSALDS+S ++ +++Q
Sbjct: 919 NLPNGLDTPLLEFSKNFSGGQIQRLAFARALLRNPRLLILDECTSALDSKSSLLLEKTIQ 978
Query: 614 QRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
S T + I H+ S ++ + R+IV++ G V E+GSFD+L+
Sbjct: 979 NLSC---TVLIITHQPSLMKLADRIIVMD-SGIVKESGSFDELM 1018
Score = 119 bits (297), Expect = 2e-26
Identities = 81/220 (36%), Positives = 122/220 (54%), Gaps = 9/220 (4%)
Query: 426 KSIHFNHVKFSYPTRPQHHIFEDLNFTVRP--GEHVCIVGPSGGGKSTVASLLLRYYDIG 483
+ F++V F+YP+R ++ +F +N +V GE V I+GPSG GKST SLLLRY+
Sbjct: 130 RGFRFDNVSFAYPSRDEN-LFSLINVSVFIPFGELVHIIGPSGSGKSTFISLLLRYFSPT 188
Query: 484 SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAI 543
G I L + + + + + +V Q+P++F TI +NI +D + R
Sbjct: 189 YGNIYLDDFPLEEIDEHVLGSTITLVCQQPVIFDMTIRENIIMRNENASESDFEEVCRL- 247
Query: 544 GQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQ 603
A +F F T + LSGGQ+QRIALARA L D ILILDE TSALD
Sbjct: 248 --ALVDEFALTFDQSYDTPC--KEASLSGGQQQRIALARALLRDTEILILDEPTSALDPI 303
Query: 604 SEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNR 643
++ +V +++ +GKTT+ I H +S I + V+V+++
Sbjct: 304 TKNLVMDAIRAH-RKGKTTLVITHDMSQINNDELVLVIDK 342
>CE28847 [P] KOG0056 Heavy metal exporter HMT1 ABC superfamily
Length = 704
Score = 149 bits (375), Expect = 2e-35
Identities = 104/390 (26%), Positives = 192/390 (48%), Gaps = 25/390 (6%)
Query: 271 KRIRNLSRQ--LQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKE 328
K + +LS + L G++ +V + S+ I Y ++ + + F L+
Sbjct: 310 KHLHSLSLRWHLSRKTGQVLRVMDRGTSSVNNILNY-----QVTEWKTQASLAFLNCLQN 364
Query: 329 ALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXX 388
A+ G +G + ++ + +TVGD F Y +
Sbjct: 365 AIIG------IGMIGGSVFVVYMI-----VHEKTLTVGDYVLFTTYLLQLYTPLNFFGTI 413
Query: 389 XXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFED 448
+ K +F+L + + + P T +I ++ F Y T + ++
Sbjct: 414 YRVIQKAFVDMENMFDLMNDEVEVKDLPHALPYTDPRGTISVKNLTFEYNTGLP--VIKN 471
Query: 449 LNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGV 508
++F + G+ V +VG SG GKST+ LL R ++ G I+ ++R++ + R+ +G+
Sbjct: 472 ISFEIGNGQTVALVGSSGSGKSTLIRLLFRLFESTEGSIEFDGIDVRNYTMHSLRQQIGI 531
Query: 509 VQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGT 568
V Q+ +LF+ TI+ NI + P +DE + A A + + + P+G T VG RG
Sbjct: 532 VPQDTVLFNDTIMYNIRFGRPD--ASDE-EVIEAAKAAMIHEKITSLPEGYATMVGERGL 588
Query: 569 QLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHR 628
+LSGG+KQR+A+AR L P + LDEATSALD+ +E + + L ++ + +T + +AHR
Sbjct: 589 KLSGGEKQRVAIARTILKKPQFIFLDEATSALDTPTERAIQKCL-EKLCKSRTGVVVAHR 647
Query: 629 VSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
+ST+ ++ ++VL++ G + E G+ +L+A
Sbjct: 648 LSTVVNADLILVLDK-GIILERGNHKELLA 676
>SPBC359.05 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1465
Score = 140 bits (353), Expect = 7e-33
Identities = 135/533 (25%), Positives = 230/533 (42%), Gaps = 52/533 (9%)
Query: 159 FVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGI 218
F+ A + + + + G R L +K L F + G +++R S+D
Sbjct: 954 FLSCAFISSSSLTMTVLCGIRSGRYLHDSMLKTILRAPMGFFETTSSGRILNRFSNDVYK 1013
Query: 219 VSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALV----YGKRIR 274
V + V+ R IQ G++ + + + +LL PL + L Y + R
Sbjct: 1014 VDEVVSLTFMFFFRNSIQVLFILGVICYSA----PLSLLLIVPLFFLYLYNRAYYVRTSR 1069
Query: 275 NLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEK---KEIHRYADEVRKVFHVGLKEA-- 329
L R + L +E LS TI+AY ++ +E D +V+ + +
Sbjct: 1070 ELKRLDNVTRSPLYAHVQESLSGLSTIRAYGMQETFVEENDLRIDTNHRVWFMFFSSSRW 1129
Query: 330 ------------LTSGAFFGVTGFVG---NVALLALLLTGTSMIKTGLMTVGDLSSFMMY 374
+ AF+G+ + N L+ L+ I GL SF++
Sbjct: 1130 QAIRVECIGDLIIFCTAFYGILSAIKGSPNPGLVGFSLSYAIQITQGL-------SFIVQ 1182
Query: 375 AVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVK 434
E + A + N R P PT G ++ FNH
Sbjct: 1183 QSVDAENNTVSVERILEYINVKSEAPEIIPEN-RPPCEWPTDG---------AVSFNHYS 1232
Query: 435 FSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNI 494
Y ++N + P E + IVG +G GKST+A L R + G+I++ N++I
Sbjct: 1233 AKY-REDLSFALNNINIEISPREKIGIVGRTGAGKSTLAMALFRIIEPTEGKIEIDNEDI 1291
Query: 495 RDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLAN 554
F L R L ++ QE +F G I +N+ P + D+ +I + A+ ++
Sbjct: 1292 TKFGLYDLRSRLSIIPQESQIFEGNIRENLD---PNHRLTDK-KIWEVLEIASLKNCISQ 1347
Query: 555 FPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQ 614
DGL + V G S GQ+Q I LAR L IL+LDEAT+++ ++++ +V Q++++
Sbjct: 1348 LEDGLYSRVAEGGANFSSGQRQLICLARVLLTSTRILLLDEATASVHAETDAIVQQTIRK 1407
Query: 615 RSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKL 667
R + +T +++AHR++T+ S R++VL+ HG V E + KL+ DS L
Sbjct: 1408 R-FKDRTILTVAHRINTVMDSDRILVLD-HGKVVEFDATKKLLENKDSMFYSL 1458
Score = 86.3 bits (212), Expect = 1e-16
Identities = 113/526 (21%), Positives = 220/526 (41%), Gaps = 63/526 (11%)
Query: 172 ILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSD-- 229
++ + G R L + +L ++ + +GD+I+ ++ D TQ +SD
Sbjct: 316 LIMLLGMRWKTELLASIYRKSLLLSSSARQNRSIGDIINYMAVD--------TQKISDLP 367
Query: 230 --------GTRAVIQGFVG-FGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQL 280
G + + +M + ++ ++L P ++A VY K+ +++ L
Sbjct: 368 IYLFIIVSGPFQIALALSNLYHLMGYSAFTGVAASVILFPCNIIVANVY-KKFQSI---L 423
Query: 281 QTSVGELTKVSEEQLSATKTIQAYCGE----KKEIH-RYADEVRKVFHVGLKEALTSGAF 335
+ +K+ E ++ ++I+ Y E +K +H R E+ + +G A+ A+
Sbjct: 424 MKNKDSRSKLMTEIINNIRSIKLYAWETPFLQKLLHIRNTKELSMLKKIGFITAIGDFAW 483
Query: 336 FGVTGFVGNVALLALLLT-GTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMK 394
T V VA A ++ G + T + +S F + L++
Sbjct: 484 IFTTIIVTTVAFGAFIIFHGKTQALTADIVFPAVSLFNLLQFPLAMLPTVISS----LLE 539
Query: 395 GAGAAARVFELNDRKPLIHPTIGKDPVT-------LENKSIHFNHVKFSYPTRPQHHIFE 447
+ + +R++E + L + + + P T LE KS F+ K + + +
Sbjct: 540 ASVSVSRIYEFLIAQELDYNGVQRFPATEIPHEICLEIKSGTFSWSKKTLKQQVTPTL-R 598
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEI-KLGNDNIRDFNLRKYRRLL 506
+NF + GE CI G G GKS++ + SG + + G+ L
Sbjct: 599 QINFVAKNGELTCIFGKVGAGKSSLLEACMGNMYKNSGSVFQCGS--------------L 644
Query: 507 GVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPR 566
Q+P +F TI +NI + D + I + F +G QT VG +
Sbjct: 645 AYAAQQPWIFDATIRENILFGSEF----DPELYEKTIHACCLKRDFEIFTEGDQTEVGQK 700
Query: 567 GTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSL--QQRSARGKTTIS 624
G LSGGQK RI+LARA I +LD+ S++D + ++L + R +
Sbjct: 701 GASLSGGQKSRISLARAIYSQADIYLLDDVLSSVDQHVSRDLIKNLFGPEGFLRTHCVVL 760
Query: 625 IAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
+ ++ ++ + + +L+ +G + E G+++ L +S L + LS+
Sbjct: 761 TTNSLNVLKEADSIYILS-NGKIVEKGNYEHLFVSTNSELKQQLSE 805
>YDR135c [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1515
Score = 140 bits (352), Expect = 9e-33
Identities = 131/518 (25%), Positives = 235/518 (45%), Gaps = 27/518 (5%)
Query: 152 YTALGGVFVVGALANVGRIVILKVTGERLVAR-LRTRTMKAALEQDATFLDHNRVGDLIS 210
Y ALG + ALA + + ++L V ++ L + L TF + +G +++
Sbjct: 995 YFALG---IGSALATLIQTIVLWVFCTIHASKYLHNLMTNSVLRAPMTFFETTPIGRILN 1051
Query: 211 RLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYG 270
R S+D V + + S ++ ++ +W+ +++ PL V + Y
Sbjct: 1052 RFSNDIYKVDALLGRTFSQFFVNAVKVTFTITVICATTWQFIFIII----PLSVFYIYYQ 1107
Query: 271 KRIRNLSRQLQTSVGELTKVS-----EEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVG 325
+ SR+L+ + +T+ +E L T++ Y +K+ H +
Sbjct: 1108 QYYLRTSRELRR-LDSITRSPIYSHFQETLGGLATVRGYSQQKRFSHINQCRIDNNMSAF 1166
Query: 326 LKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXX 385
+ +G++ +L +K G +T G + + YA+
Sbjct: 1167 YPSINANRWLAYRLELIGSIIILGAATLSVFRLKQGTLTAGMVGLSLSYALQITQTLNWI 1226
Query: 386 XXXXXELMKGAGAAARVFELNDRK---PLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQ 442
E+ + R+ E D K PLI I FN+ Y RP+
Sbjct: 1227 VRMTVEVETNIVSVERIKEYADLKSEAPLIVEGHRPPKEWPSQGDIKFNNYSTRY--RPE 1284
Query: 443 HH-IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRK 501
+ + +N ++P E V IVG +G GKS++ L R + G I + N I + L
Sbjct: 1285 LDLVLKHINIHIKPNEKVGIVGRTGAGKSSLTLALFRMIEASEGNIVIDNIAINEIGLYD 1344
Query: 502 YRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFP-DGLQ 560
R L ++ Q+ +F GT+ +NI P DE I RA+ ++ + + + DGL
Sbjct: 1345 LRHKLSIIPQDSQVFEGTVRENID---PINQYTDEA-IWRALELSHLKEHVLSMSNDGLD 1400
Query: 561 TTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGK 620
+ G LS GQ+Q + LARA L+ IL+LDEAT+A+D ++++VV +++ + + + +
Sbjct: 1401 AQLTEGGGNLSVGQRQLLCLARAMLVPSKILVLDEATAAVDVETDKVVQETI-RTAFKDR 1459
Query: 621 TTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
T ++IAHR++TI S R+IVL+ +G VAE S +L++
Sbjct: 1460 TILTIAHRLNTIMDSDRIIVLD-NGKVAEFDSPGQLLS 1496
Score = 92.0 bits (227), Expect = 3e-18
Identities = 112/487 (22%), Positives = 202/487 (40%), Gaps = 59/487 (12%)
Query: 206 GDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVM 265
GD+++ +S D Q+L+ + G + + +KL M + + V+
Sbjct: 403 GDIVNLMSVDV-----QKLQDLTQWLNLIWSGPFQIIICLYSLYKLLGNSMWVGVIILVI 457
Query: 266 ALVYGKRIRNLSRQLQTSV----GELTKVSEEQLSATKTIQAYCGEKK-----EIHRYAD 316
+ + + ++LQ S E T+V E L+ K+++ Y EK E R
Sbjct: 458 MMPLNSFLMRIQKKLQKSQMKYKDERTRVISEILNNIKSLKLYAWEKPYREKLEEVRNNK 517
Query: 317 EVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGL----MTVGDLSSFM 372
E++ + +G A+TS F V V + T + T L +T+ +L SF
Sbjct: 518 ELKNLTKLGCYMAVTSFQFNIVPFLVSCCTFAVFVYTEDRALTTDLVFPALTLFNLLSFP 577
Query: 373 MYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFN- 431
+ + ++ + + R+F + L ++ + P + N
Sbjct: 578 LMIIPMVLNS---------FIEASVSIGRLFTFFTNEELQPDSVQRLPKVKNIGDVAINI 628
Query: 432 --HVKFSYPTRPQHHI-FEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIK 488
F + +P++ + +++NF + G CIVG G GK+ + S +L
Sbjct: 629 GDDATFLWQRKPEYKVALKNINFQAKKGNLTCIVGKVGSGKTALLSCML----------- 677
Query: 489 LGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANC 548
D R + V Q P + +GT+ +NI + D + I
Sbjct: 678 --GDLFRVKGFATVHGSVAYVSQVPWIMNGTVKENILFGHRY----DAEFYEKTIKACAL 731
Query: 549 TKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVV 608
T LA DG +T VG +G LSGGQK R++LARA +LD+ +A+D E V
Sbjct: 732 TIDLAILMDGDKTLVGEKGISLSGGQKARLSLARAVYARADTYLLDDPLAAVD----EHV 787
Query: 609 AQSLQQR------SARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDS 662
A+ L + KT + ++VS + + + +L+ +G + + G++D++ DS
Sbjct: 788 ARHLIEHVLGPNGLLHTKTKVLATNKVSALSIADSIALLD-NGEITQQGTYDEITKDADS 846
Query: 663 SLNKLLS 669
L KLL+
Sbjct: 847 PLWKLLN 853
>SPAC3F10.11c [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1478
Score = 139 bits (351), Expect = 1e-32
Identities = 137/518 (26%), Positives = 224/518 (42%), Gaps = 50/518 (9%)
Query: 163 ALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKS 222
AL ++ + I + L +KA L +F + G +++R SSD V +
Sbjct: 971 ALISLSSLTITVFCAIKSCRYLHDSMVKAVLRAPMSFFETTPTGRILNRFSSDVYRVDEV 1030
Query: 223 VTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMA---LVYGKRIRNLSRQ 279
+++ R + Q + F +++ I + M+L+ P + + Y + R L R
Sbjct: 1031 ISRVFMFFFRNLFQ--IVF-VLAVICYSSPMFMILIVPLFFLYRYNQVYYTQTSRELKRL 1087
Query: 280 LQTSVGELTKVSEEQLSATKTIQAYCGEKKEI----------HR-----YADEVRKVFHV 324
+ L +E L TI+AY E I HR ++ + V
Sbjct: 1088 DSVTRSPLYAHFQESLGGLSTIRAYDMEDTFISENDIRVDTNHRIWFLYFSSNRWQAIRV 1147
Query: 325 GLKEALT--SGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXX 382
AL S AFFGV V G G + + YAV
Sbjct: 1148 EAIGALVVFSSAFFGVLSAV-----------------RGNPNSGLVGLSLSYAVQITQSL 1190
Query: 383 XXXXXXXXELMKGAGAAARVFE---LNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPT 439
++ + R+ E L P I P + +I F+H Y
Sbjct: 1191 TFVVRQSVDVETNIVSVERMLEYIGLPSEAPSIIPDHRPPEGWPSHGAIKFDHYSVRYRE 1250
Query: 440 RPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNL 499
+ D++ ++P E + IVG +G GKST+ L R + SG+I+L + NI L
Sbjct: 1251 NLPL-VLNDISVNIKPQEKIGIVGRTGAGKSTLTLALFRLIEPTSGDIQLDDINITSIGL 1309
Query: 500 RKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGL 559
R L ++ QE F GTI +N+ P DE I A+ A+ +F+ GL
Sbjct: 1310 HDLRSRLAIIPQENQAFEGTIRENLD---PNANATDE-EIWHALEAASLKQFIQTLDGGL 1365
Query: 560 QTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARG 619
+ V G LS GQ+Q + L RA L +L+LDEAT+A+D +++ +V +++++R
Sbjct: 1366 YSRVTEGGANLSSGQRQLMCLTRALLTPTRVLLLDEATAAVDVETDAIVQRTIRER-FND 1424
Query: 620 KTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+T ++IAHR++T+ S+R++VL+ HG V E S KL+
Sbjct: 1425 RTILTIAHRINTVMDSNRILVLD-HGKVVEFDSTKKLL 1461
Score = 94.4 bits (233), Expect = 5e-19
Identities = 126/528 (23%), Positives = 223/528 (41%), Gaps = 74/528 (14%)
Query: 175 VTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTR-- 232
V G R + L T + +L + VGD+++ +S D TQ + D T
Sbjct: 337 VLGMRWRSELITAIYRKSLRLSSAARQSRSVGDIVNYMSVD--------TQKVCDLTMFL 388
Query: 233 -AVIQG-------------FVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSR 278
++ G VG+G +S V LL P V+A ++ KR +N R
Sbjct: 389 FVIVSGPFQIVLALTNLYHLVGYGALSG-----AFVTFLLFPCNVVIASIF-KRFQN--R 440
Query: 279 QLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGV 338
Q++ ++ E ++ ++I+ Y E + + ++R + + + + G+
Sbjct: 441 QMKNKDAR-SQFMTEIINNIRSIKLYAWENIFLQKLL-QLRNTRELRMLKKI------GI 492
Query: 339 TGFVGNVA------LLALLLTGTSMI---KTGLMTVGDLSSFMMYAVXXXXXXXXXXXXX 389
+GN L++ GT ++ KT +++V + + +
Sbjct: 493 VNTIGNFTWLFAPILVSAATFGTFIVLYGKTRVLSVDIVFACLSLFNLLQFPLTMLPIVV 552
Query: 390 XELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVK--FSYPTRPQHHI-- 445
+++ + A +R++ L + + P E + K FS+ Q+
Sbjct: 553 SSVLEASVAISRIYGFLTAGELDSNAVQRYPANKEPSGVCLEIKKGTFSWSGPGQNAAEP 612
Query: 446 -FEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEI-KLGNDNIRDFNLRKYR 503
D++F R GE CIVG G GKS++ L SG + + G+
Sbjct: 613 TLRDIDFVARRGELCCIVGKVGMGKSSLLEACLGNMQKHSGSVFRCGS------------ 660
Query: 504 RLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTV 563
+ Q+P + + TI +NI + + + E I RA + LA DG QT V
Sbjct: 661 --IAYAAQQPWILNATIQENILFGLELDPEFYEKTI-RACCLLRDFEILA---DGDQTEV 714
Query: 564 GPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQ-SEEVVAQSLQQRSARGKTT 622
G +G LSGGQK RI+LARA I +LD+ SA+D + ++V L +
Sbjct: 715 GEKGISLSGGQKARISLARAVYSRSDIYLLDDILSAVDQHVNRDLVRNLLGSKGLLRSRC 774
Query: 623 ISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
+ ++ T+ + +I + R+G + E+GSF +L + PDS L +LLS+
Sbjct: 775 VILSTNSLTVLKEASMIYMLRNGKIIESGSFTQLSSSPDSQLFQLLSE 822
>CE25015 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1528
Score = 139 bits (350), Expect = 1e-32
Identities = 132/521 (25%), Positives = 228/521 (43%), Gaps = 23/521 (4%)
Query: 147 TSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTM-KAALEQDATFLDHNRV 205
+ TQ + V +G +V I+ G +RL T+ + + F D +
Sbjct: 1012 SETQIRLGIYAVLGMGQATSVCAASIIMALGMVCASRLLHATLLENIMRSPMAFFDVTPL 1071
Query: 206 GDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVM 265
G +++R D V + + +S R + +++ I W + LL P +
Sbjct: 1072 GRILNRFGKDVDGVDTDIPRTMSMFIRTAVSSIE---IIAIILWATPLAISLLLP---LF 1125
Query: 266 ALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVG 325
Y R L R S + +E + +I+AY K I V +
Sbjct: 1126 IRFYVSTSRQLKRLESASRSPIYSHFQESIQGASSIRAYGVVDKFIRESQHRVDENLATY 1185
Query: 326 LKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXX 385
+ + VGN+ +L+ + ++ G + + YA+
Sbjct: 1186 YPSIVANRWLAVRLEMVGNLIVLSSAGAAVYFRDSPGLSAGLVGLSVSYALNITQTLNWA 1245
Query: 386 XXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHV----KFSYPTRP 441
EL A R+ E I PT G + +L KS N FS RP
Sbjct: 1246 VRMTSELETNIVAVERINEYT-----ITPTEGNNSQSLAPKSWPENGEISIKNFSVRYRP 1300
Query: 442 QHH-IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLR 500
+ + + P E + IVG +G GKS++ L R + G I++ NI D L
Sbjct: 1301 GLDLVLHGVTAHISPCEKIGIVGRTGAGKSSLTLALFRIIEADGGCIEIDGTNIADLLLE 1360
Query: 501 KYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQ 560
+ R L +V Q+P+LFSGT+ N+ P +D+ +I A+ A+ F+ + +GL
Sbjct: 1361 QLRSRLTIVPQDPVLFSGTMRMNLD---PFFAFSDD-QIWEALRNAHLDSFVKSLQEGLH 1416
Query: 561 TTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGK 620
+ G LS GQ+Q I LARA L +L+LDEA +A+D +++ ++ ++++++ +
Sbjct: 1417 HHISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLLQKTIREQ-FKDC 1475
Query: 621 TTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPD 661
T ++IAHR++T+ S R++VL++ G VAE + KL++ PD
Sbjct: 1476 TVLTIAHRLNTVMDSDRLLVLDK-GCVAEFDTPKKLLSNPD 1515
Score = 83.6 bits (205), Expect = 1e-15
Identities = 62/237 (26%), Positives = 119/237 (50%), Gaps = 23/237 (9%)
Query: 425 NKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGS 484
+ +I + F++ ++ + D+ F ++ G+ V IVG G GKS++ LL + S
Sbjct: 611 DSAIKMDGGSFAWGSKEEDRKLHDITFNIKRGQLVAIVGRVGSGKSSLLHALLGEMNKLS 670
Query: 485 GEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIG 544
G +++ + V Q + + ++ +NI + P D I
Sbjct: 671 GSVQVNGS-------------VAYVPQLAWIQNLSLRNNILFNRPY----DAKLYQNVIE 713
Query: 545 QANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQS 604
+ L + P +T +G +G LSGGQKQR++LARA + I++LD+ SA+DS
Sbjct: 714 NCALVQDLESLPAEDRTEIGEKGINLSGGQKQRVSLARAVYQNAEIVLLDDPLSAVDSHV 773
Query: 605 EEVVAQSLQQRSARG----KTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ + +++ +A G KT + + H ++ ++H +VIVL + T++E G++ +L+
Sbjct: 774 GKHIFENVIS-TATGCLGTKTRVLLTHGLTYLKHCDQVIVL-KDETISEMGTYQELM 828
>Hs21541820 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1463
Score = 138 bits (347), Expect = 3e-32
Identities = 142/537 (26%), Positives = 241/537 (44%), Gaps = 31/537 (5%)
Query: 145 GLTSTQFY-TALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHN 203
G + +FY T + V +L + R V+ + A L R + L TF +
Sbjct: 931 GSSDIRFYLTVYATIAGVNSLCTLLRAVLFAAGTLQAAATLHRRLLHRVLMAPVTFFNAT 990
Query: 204 RVGDLISRLSSDAGIVSKSVT--QNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPP 261
G +++R S D S+ N+ A + G + + S + W ++LL PP
Sbjct: 991 PTGRILNRFSFDVACADDSLPFILNILLANAAGLLGLLAV-LGSGLPW-----LLLLLPP 1044
Query: 262 LGVMALVYGKRIRNLSRQLQTSVGELT-KVSEEQLSATKTIQAYCGEKKEIHRYADEVRK 320
L +M + R SR+L+ +G LT L+ T + +R+ +E +
Sbjct: 1045 LSIMYYHVQRHYRASSRELRR-LGSLTLSPLYSHLADTLAGLSVLRATGATYRFEEENLR 1103
Query: 321 VFHVGLKEALTSGAFFGVTGF----VGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAV 376
+ + + + A +G + A+ + GL G + + YA+
Sbjct: 1104 LLELNQRCQFATSATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLSLSYAL 1163
Query: 377 XXXXXXXXXXXXXXELMKGAGAAARVFELN---DRKPLIHPT-IGKDPVTLENKSIHFNH 432
+ + R+ E ++P P +G +T + F
Sbjct: 1164 SLTGLLSGLVSSFTQTEAMLVSVERLEEYTCDLPQEPQGQPLQLGTGWLT--QGGVEFQD 1221
Query: 433 VKFSY-PTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGN 491
V +Y P P + + + F V+PGE V IVG +G GKS++ +L R + SG + L
Sbjct: 1222 VVLAYRPGLP--NALDGVTFCVQPGEKVGIVGRTGSGKSSLLLVLFRLLEPSSGRVLLDG 1279
Query: 492 DNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKF 551
+ L + R L ++ QEP LFSGT+ +N+ PQ L D + +A+ Q + ++
Sbjct: 1280 VDTSQLELAQLRSQLAIIPQEPFLFSGTVRENLD---PQGLHKDRA-LWQALKQCHLSEV 1335
Query: 552 LANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQS 611
+ + GL +G G LS GQ+Q + LARA L D IL +DEAT+++D ++++++ Q+
Sbjct: 1336 ITSM-GGLDGELGEGGRSLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQT 1394
Query: 612 LQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLL 668
+ +R A KT ++IAHR++TI +S RV+VL V E S L P S +LL
Sbjct: 1395 ICKRFA-NKTVLTIAHRLNTILNSDRVLVLQAE-RVVELDSPATLRNQPHSLFQQLL 1449
Score = 60.8 bits (146), Expect = 7e-09
Identities = 54/193 (27%), Positives = 86/193 (43%), Gaps = 22/193 (11%)
Query: 453 VRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQE 512
V+ G V VG G GKS++ + + +GE+ ++ +R + G+ QE
Sbjct: 594 VKKGMLVGTVGKVGCGKSSLLAAI-------AGELHRLRGHVA---VRGLSKGFGLATQE 643
Query: 513 PMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSG 572
P + TI DNI + D + L+ P G QT VG +G LSG
Sbjct: 644 PWIQFATIRDNILFGK----TFDAQLYKEVLEACALNDDLSILPAGDQTEVGEKGVTLSG 699
Query: 573 GQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARG----KTTISIAHR 628
GQ+ RIALARA + + +LD+ +A+D+ VA R G T + HR
Sbjct: 700 GQRARIALARAVYQEKELYLLDDPLAAVDAD----VANHPLHRCILGMLSYTTRLLCTHR 755
Query: 629 VSTIQHSSRVIVL 641
++ + V+++
Sbjct: 756 TEYLERADAVLLM 768
>7297388 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1327
Score = 137 bits (346), Expect = 4e-32
Identities = 126/519 (24%), Positives = 234/519 (44%), Gaps = 29/519 (5%)
Query: 158 VFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAG 217
+ V+ L V R + + RL + F + N G +++R S D G
Sbjct: 792 ITVLTILVTVARSFLFFNLAMKASIRLHNSMFRGITRAAMYFFNTNPSGRILNRFSKDMG 851
Query: 218 IVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGV----MALVYGKRI 273
V + + + D VIQ F+ + + + + ++ LG+ + Y K
Sbjct: 852 QVDEILPAVMMD----VIQIFLALAGIVIVIAVVNPLFLIPTVVLGIIFYQLRTFYLKTS 907
Query: 274 RNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEK---KEIHRYADEVRKVFHVGLKEAL 330
R++ R + + L+ TI+A+ ++ E Y D F++ + +
Sbjct: 908 RDVKRMEAITRSPVYSHLAASLTGLSTIRAFGAQRVLEAEFDNYQDMHSSAFYMFISTSR 967
Query: 331 TSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXX 390
G + + +A++ L S GD+ + A+
Sbjct: 968 AFGYWLDCFCVI-YIAIITL-----SFFIFPPANGGDVGLAITQAMGMTGMVQWGMRQSA 1021
Query: 391 ELMKGAGAAARVFELNDRKP---LIHPTIGKDPVTL-ENKSIHFNHVKFSYPTRPQ-HHI 445
EL A RV E D +P L P K P + E I F+ + Y P+ ++
Sbjct: 1022 ELENTMTAVERVVEYEDIEPEGALEAPADKKPPKSWPEQGKIVFDELSLRYTPDPKSENV 1081
Query: 446 FEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRL 505
+ L+F ++P E V IVG +G GKS++ + L R G + + + + L R
Sbjct: 1082 LKSLSFVIKPKEKVGIVGRTGAGKSSLINALFRL-SYNDGSVLIDKRDTSEMGLHDLRSK 1140
Query: 506 LGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGP 565
+ ++ QEP+LFSGT+ N+ P + +D+ ++ R++ + + +A+ P GLQ+ +
Sbjct: 1141 ISIIPQEPVLFSGTMRYNLD---PFDEYSDD-KLWRSLEEVKLKEVVADLPSGLQSKITE 1196
Query: 566 RGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISI 625
GT S GQ+Q + LARA L + IL++DEAT+ +D Q++ ++ +++ + + T ++I
Sbjct: 1197 GGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDGLIQTTIRNK-FKECTVLTI 1255
Query: 626 AHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSL 664
AHR+ TI S +V+V++ G E G+ +L+ + DS +
Sbjct: 1256 AHRLHTIMDSDKVLVMDA-GRAVEFGTPYELLTLADSKV 1293
Score = 104 bits (259), Expect = 5e-22
Identities = 64/208 (30%), Positives = 106/208 (50%), Gaps = 18/208 (8%)
Query: 449 LNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGV 508
+N V+PG + IVG +G GKS++ +L SGEIK+ +
Sbjct: 438 VNLRVQPGTMLGIVGRTGSGKSSLIQAILGELPAESGEIKVNGS-------------MSY 484
Query: 509 VQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGT 568
QEP LFSGT+ NI + P D R ++ + + + P +T VG RG
Sbjct: 485 ASQEPWLFSGTVRQNILFGQPM----DRRRYAKVVKKCALERDFELLPFKDKTIVGERGA 540
Query: 569 QLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHR 628
LSGGQK RI+LARA + SI +LD+ SA+D+ + + + R + I H+
Sbjct: 541 SLSGGQKARISLARAVYRETSIYLLDDPLSAVDTHVARHLFEQCMRGYLRERIVILATHQ 600
Query: 629 VSTIQHSSRVIVLNRHGTVAETGSFDKL 656
+ +QH+ +++++++ G V+ G+++ L
Sbjct: 601 LQFLQHADQIVIMDK-GRVSAVGTYESL 627
>Hs22057784 [U] KOG0058 Peptide exporter ABC superfamily
Length = 359
Score = 137 bits (345), Expect = 6e-32
Identities = 84/210 (40%), Positives = 118/210 (56%), Gaps = 31/210 (14%)
Query: 461 IVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTI 520
+VGP G GKSTV SLLLR +D SG I L +IR N R +G
Sbjct: 175 LVGPGGSGKSTVLSLLLRLFDPASGTISLDGHDIRQLNPVWLRSKIG------------- 221
Query: 521 LDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIAL 580
T++ R AN + NFP G T VG +G LSGGQKQRIA+
Sbjct: 222 ----------------TQVQRVAEVANAVVLIRNFPQGFNTVVGEKGVLLSGGQKQRIAI 265
Query: 581 ARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIV 640
ARA L +P IL+LDEATSALD+++E +V ++L G+T + IAH +STI++++ V V
Sbjct: 266 ARALLKNPKILLLDEATSALDAENEYLVQEALDP-LMDGRTALVIAHHLSTIKNANMVAV 324
Query: 641 LNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
L++ G + E G ++L++ P+ KL++K
Sbjct: 325 LDQ-GKITEYGKHEELLSKPNGIYRKLMNK 353
Score = 98.2 bits (243), Expect = 4e-20
Identities = 58/184 (31%), Positives = 99/184 (53%), Gaps = 11/184 (5%)
Query: 118 PTVIGKLLDIARXXXXXXXXXXXTMIFGLTSTQFYTALGGVFVVGALANVGRIVILKVTG 177
P +GK++D T+ + T+ L GVF+ GA AN R+ +++ +
Sbjct: 4 PFFLGKIID--------AIYTNPTVDYSDNLTRLCLGLSGVFLCGAAANAIRVYLMQTSR 55
Query: 178 ERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQG 237
+R+V RLRT + L Q+ F D G+LI+RLSSD ++ +SVT+NLSDG RA +
Sbjct: 56 QRVVKRLRTSLFSSILGQEVAFFDKAGTGELINRLSSDTALLGRSVTENLSDGLRAGARA 115
Query: 238 FVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSA 297
VG MM +S ++ + + ++ ++YG+ +R L++ Q S+ + T +E+ S
Sbjct: 116 SVGIRMMFCVSPNRATFVVSVVRLVSIIDVIYGRYLRKLTKVTQDSLAQAT---QEERSV 172
Query: 298 TKTI 301
T +
Sbjct: 173 TALV 176
>CE04425 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1421
Score = 135 bits (341), Expect = 2e-31
Identities = 124/500 (24%), Positives = 218/500 (42%), Gaps = 51/500 (10%)
Query: 184 LRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGF-G 242
L L+ ++ F D N G +++R S D G+ + + + FVG G
Sbjct: 886 LHNSMFDCVLKTESEFFDKNSEGMILNRFSKDIGLTDDLLAFTYFEFVFGTLT-FVGIVG 944
Query: 243 MMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQ 302
++S + + + +Y R R L R + L + TI+
Sbjct: 945 LVSMVRPIVILACAFITAGFYFCRKMYVHRSRELKRIEAAARSPLNTTITSTVHGLSTIR 1004
Query: 303 AYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFG------VTGFVGNVALLALLLTGTS 356
AY E + I ++ + V+ L S +FG V+ FV VA++ +L T
Sbjct: 1005 AYRKENEMIEKFC-ALHDVYMAAYNMGLLSARWFGICIDFLVSVFVSIVAIVVVLQYET- 1062
Query: 357 MIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELND-------RK 409
+TVG++ ++ AV EL G + RV E R+
Sbjct: 1063 ------LTVGEVGLCLVCAVQLSGFFSWIMRQSAELENGMVSVERVLEYTKLKSEEEARR 1116
Query: 410 P--------LIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCI 461
P L++ K + EN S+++ K + ++L+F V G+ + +
Sbjct: 1117 PHDAYLDKQLLNSWPTKGEIEFENVSVNYGETK----------VLKNLSFVVLGGQKIGV 1166
Query: 462 VGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTIL 521
VG +G GKST+ ++ + SG + + ++ +L R + ++ QEP++FSGT+
Sbjct: 1167 VGRTGAGKSTLIKIIFGLKEYCSGRVTIDGVDLDHISLNFRRGGMSIIPQEPVIFSGTVR 1226
Query: 522 DNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALA 581
+N+ P + +D T I A+ Q + + GL +G RG LS GQ+Q LA
Sbjct: 1227 ENLD---PFDEYDDAT-IWFALEQCELKRSITK-EKGLNVELGQRGVSLSVGQRQLFCLA 1281
Query: 582 RAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVL 641
RA + IL++DEAT+ +D ++ + ++++ + T I++AHR+ TI +S V+V
Sbjct: 1282 RAMIHRSKILVIDEATANVDGVTDACIQKTIRD-FFKNATIITVAHRLHTIMNSDNVMVF 1340
Query: 642 NRHGTVAETGSFDKLIAIPD 661
+ E FDK I + D
Sbjct: 1341 EK----GELVEFDKPITLLD 1356
Score = 84.3 bits (207), Expect = 6e-16
Identities = 62/218 (28%), Positives = 101/218 (45%), Gaps = 20/218 (9%)
Query: 441 PQHHIF--EDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFN 498
P H ++ +DL+F G I+G G GKS++ +L + G + +
Sbjct: 493 PLHVVYAVQDLSFEFVAGTCYGIIGSVGSGKSSLLLTILSESRMTRGNLSVNGS------ 546
Query: 499 LRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDG 558
QEP +F+G+I DNI + ++ R A+ T L F +G
Sbjct: 547 -------FAYCAQEPWIFTGSIQDNIVFGSEF----NKERYENALELCLLTPDLRQFANG 595
Query: 559 LQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSAR 618
T VG G+ LSGGQ+ R+ALARA D I +LD+ SA+D+ + + ++L +
Sbjct: 596 DMTIVGDNGSTLSGGQRARVALARAVYADADIYLLDDPLSAVDAHVGKKLYENLIRGFLS 655
Query: 619 GKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
K I + H++ + VI++ + V GS D+L
Sbjct: 656 DKLVILVTHQIHFLSELDSVILMKNNKMVG-NGSLDEL 692
>7301757 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1346
Score = 135 bits (341), Expect = 2e-31
Identities = 123/528 (23%), Positives = 234/528 (44%), Gaps = 30/528 (5%)
Query: 151 FYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLIS 210
+ T LG +V + G + R+ L R + F + N G +++
Sbjct: 795 YATILGATLIVYLIRTFGFFKMCL----RISLHLHDRLFRGITRASMYFFNTNSSGRILN 850
Query: 211 RLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVY- 269
R S D V + L D +I +++ ++ L ++ LG++ +Y
Sbjct: 851 RFSKDIRTVDTDLPHTLLDCLAFIIDVSGVVIIVAIANYWLLIPAAIIGVILGMIRYLYV 910
Query: 270 --GKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLK 327
+ ++ L ++ V LT + + L+ + +QA ++E H Y + + + L
Sbjct: 911 NTSRSVKRLESISRSPVFSLTNQTFQGLTTIRALQAQSALEQEFHEYQNTNTSAWFLFLS 970
Query: 328 EALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXX 387
+ V V A+ T + ++ GD+ ++++
Sbjct: 971 CTRAFALWSDVLCIVYMTAV-----TFSFLLLKDEFDSGDVGLAILHSTTMTGMCQWGMR 1025
Query: 388 XXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKS-------IHFNHVKFSYPTR 440
EL + RV E ++ + + P + KS I F + K Y +
Sbjct: 1026 QTAELENQMTSVERVLEYTEQPS---EALLETPEKFKPKSEWPSKGRIEFINFKLRYSPK 1082
Query: 441 PQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLR 500
+ + +DLNFT+ P E + IVG +G GKS++ + R G I++ + +I L
Sbjct: 1083 -EAPVLKDLNFTIEPREKIGIVGRTGAGKSSIIQSIFRLA-CNEGMIRIDDVDIEHIGLH 1140
Query: 501 KYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQ 560
R + ++ Q+P+LFSGT+ N+ P + +DE + +A+G +++ GL
Sbjct: 1141 DLRSQVSIIPQDPVLFSGTLRYNLD---PMDERSDE-EMWKALGDVELRSYVSTLIGGLN 1196
Query: 561 TTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGK 620
+ G+ S GQ+Q + LARA L ILI+DEAT+ +D ++++++ Q+++ + A
Sbjct: 1197 CRMYDGGSNFSVGQRQLVCLARAILRHNKILIMDEATANVDPETDKLIQQTIRSKFAH-C 1255
Query: 621 TTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLL 668
T ++IAHR+ T+ S RV+V++ G V E G +L+ L +L+
Sbjct: 1256 TVLTIAHRLHTVMDSDRVLVMDA-GEVRELGHPYELLQRTGGYLRQLV 1302
Score = 81.6 bits (200), Expect = 4e-15
Identities = 62/233 (26%), Positives = 100/233 (42%), Gaps = 20/233 (8%)
Query: 426 KSIHFNHVKFSYPTRPQHH--IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG 483
K + +V S+ T H ED + ++ +VGP G GKS+ ++LL I
Sbjct: 418 KCVVLKNVSASWDTSDGHANCAIEDFSTDIKDQTLAAVVGPVGAGKSSFLNVLLGEVGID 477
Query: 484 SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAI 543
GE + + QE +F GTI DNI + +E R + +
Sbjct: 478 KGEAMVHGK-------------ISYASQESWVFEGTIRDNIVFVEDY----NERRYKKVV 520
Query: 544 GQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQ 603
+ + P G T VG RG LSGGQK R++LARA I +LD+ SA+D+
Sbjct: 521 KVCGLERDMELLPRGDLTVVGERGVSLSGGQKARVSLARAVYRKADIYLLDDPLSAVDTH 580
Query: 604 SEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
+ + + K I + H+V + ++++ G + GS+ +L
Sbjct: 581 VGKHIFDRCIRDFLSNKIRILVTHQVQYLFDVEHLLLMG-SGKIMAQGSYQEL 632
>At1g30400 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1622
Score = 135 bits (339), Expect = 3e-31
Identities = 136/526 (25%), Positives = 241/526 (44%), Gaps = 28/526 (5%)
Query: 160 VVGALANVGRIVILKVTGERLVA-------RLRTRTMKAALEQDATFLDHNRVGDLISRL 212
+V AL + G++ + + L+ ++ + + L F N +G +I+R
Sbjct: 956 IVYALLSFGQVSVTLINSYWLIMSSLYAAKKMHDAMLGSILRAPMVFFQTNPLGRIINRF 1015
Query: 213 SSDAGIVSKSVTQ--NLSDGTRA-VIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVY 269
+ D G + ++V N+ G+ A ++ + G++S +S L +M LL G L Y
Sbjct: 1016 AKDMGDIDRTVAVFVNMFMGSIAQLLSTVILIGIVSTLS--LWAIMPLLVVFYGAY-LYY 1072
Query: 270 GKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKK--EIH-RYADEVRKVFHVGL 326
R + R T+ + E L+ +I+AY + EI+ R D + V +
Sbjct: 1073 QNTSREIKRMDSTTRSPVYAQFGEALNGLSSIRAYKAYDRMAEINGRSMDNNIRFTLVNM 1132
Query: 327 KEALTSGAFFGVTG--FVGNVALLALLLTGTSMIKTGLM-TVGDLSSFMMYAVXXXXXXX 383
G V G V A LA++ G + + T+G L S+ +
Sbjct: 1133 AANRWLGIRLEVLGGLMVWLTASLAVMQNGKAANQQAYASTMGLLLSYALSITSSLTAVL 1192
Query: 384 XXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQ- 442
+ E+ PL+ P + SI F V Y RP+
Sbjct: 1193 RLASLAENSLNSVERVGNYIEIPSEAPLVIENNRPPPGWPSSGSIKFEDVVLRY--RPEL 1250
Query: 443 HHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKY 502
+ ++F + P + V IVG +G GKS++ + L R ++ G I + +I F L
Sbjct: 1251 PPVLHGVSFLISPMDKVGIVGRTGAGKSSLLNALFRIVELEKGRILIDECDIGRFGLMDL 1310
Query: 503 RRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTT 562
R++LG++ Q P+LFSGT+ N+ P ND + ++ +A+ + P GL
Sbjct: 1311 RKVLGIIPQAPVLFSGTVRFNLD---PFSEHND-ADLWESLERAHLKDTIRRNPLGLDAE 1366
Query: 563 VGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTT 622
V G S GQ+Q ++LARA L IL+LDEAT+A+D +++ ++ +++++ + T
Sbjct: 1367 VTEAGENFSVGQRQLLSLARALLRRSKILVLDEATAAVDVRTDVLIQKTIRE-EFKSCTM 1425
Query: 623 ISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLL 668
+ IAHR++TI +V+VL+ G V E S + L++ +SS +K++
Sbjct: 1426 LIIAHRLNTIIDCDKVLVLD-SGKVQEFSSPENLLSNGESSFSKMV 1470
Score = 92.0 bits (227), Expect = 3e-18
Identities = 62/237 (26%), Positives = 114/237 (47%), Gaps = 17/237 (7%)
Query: 420 PVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRY 479
P+ +I + FS+ ++ ++N + G V +VG +G GK+++ S +L
Sbjct: 606 PIEPGQPAISIRNGYFSWDSKADRPTLSNINLDIPLGSLVAVVGSTGEGKTSLISAML-- 663
Query: 480 YDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRI 539
GE+ +D R + V Q +F+ T+ DNI + P D+ +
Sbjct: 664 -----GELPARSDATVTL-----RGSVAYVPQVSWIFNATVRDNILFGAPF----DQEKY 709
Query: 540 SRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSA 599
R I L P G T +G RG +SGGQKQR+++ARA + + ILD+ SA
Sbjct: 710 ERVIDVTALQHDLELLPGGDLTEIGERGVNISGGQKQRVSMARAVYSNSDVCILDDPLSA 769
Query: 600 LDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
LD+ + V + +R T + + +++ + ++++++ GTV E G++++L
Sbjct: 770 LDAHVGQQVFEKCIKRELGQTTRVLVTNQLHFLSQVDKILLVH-EGTVKEEGTYEEL 825
>CE29412 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1534
Score = 134 bits (337), Expect = 5e-31
Identities = 127/521 (24%), Positives = 228/521 (43%), Gaps = 17/521 (3%)
Query: 147 TSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTM-KAALEQDATFLDHNRV 205
+ TQ + V +G +V I+ G +RL T+ + + F D +
Sbjct: 1012 SETQIRLGIYAVLGMGQATSVCAASIIMALGMVCASRLLHATLLENIMRSPMAFFDVTPL 1071
Query: 206 GDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVM 265
G +++R D ++ + + A++Q F + + + + + ++ +
Sbjct: 1072 GRILNRFGKDIDVIDYRLPSCIMTFVGAIVQAVTIFAVPIYATPLSSFPITIVLIGYYFL 1131
Query: 266 ALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVG 325
Y R L R S + +E + +I+AY K I V +
Sbjct: 1132 LRFYVSTSRQLKRLESASRSPIYSHFQESIQGASSIRAYGVVDKFIRESQHRVDENLATY 1191
Query: 326 LKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXX 385
+ + VGN+ +L+ + ++ G + + YA+
Sbjct: 1192 YPSIVANRWLAVRLEMVGNLIVLSSAGAAVYFRDSPGLSAGLVGLSVSYALNITQTLNWA 1251
Query: 386 XXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHV----KFSYPTRP 441
EL A R+ E I PT G + +L KS N FS RP
Sbjct: 1252 VRMTSELETNIVAVERINEYT-----ITPTEGNNSQSLAPKSWPENGEISIKNFSVRYRP 1306
Query: 442 QHH-IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLR 500
+ + + P E + IVG +G GKS++ L R + G I++ NI D L
Sbjct: 1307 GLDLVLHGVTAHISPCEKIGIVGRTGAGKSSLTLALFRIIEADGGCIEIDGTNIADLLLE 1366
Query: 501 KYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQ 560
+ R L +V Q+P+LFSGT+ N+ P +D+ +I A+ A+ F+ + +GL
Sbjct: 1367 QLRSRLTIVPQDPVLFSGTMRMNLD---PFFAFSDD-QIWEALRNAHLDSFVKSLQEGLH 1422
Query: 561 TTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGK 620
+ G LS GQ+Q I LARA L +L+LDEA +A+D +++ ++ ++++++ +
Sbjct: 1423 HHISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLLQKTIREQ-FKDC 1481
Query: 621 TTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPD 661
T ++IAHR++T+ S R++VL++ G VAE + KL++ PD
Sbjct: 1482 TVLTIAHRLNTVMDSDRLLVLDK-GCVAEFDTPKKLLSNPD 1521
Score = 83.6 bits (205), Expect = 1e-15
Identities = 62/237 (26%), Positives = 119/237 (50%), Gaps = 23/237 (9%)
Query: 425 NKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGS 484
+ +I + F++ ++ + D+ F ++ G+ V IVG G GKS++ LL + S
Sbjct: 611 DSAIKMDGGSFAWGSKEEDRKLHDITFNIKRGQLVAIVGRVGSGKSSLLHALLGEMNKLS 670
Query: 485 GEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIG 544
G +++ + V Q + + ++ +NI + P D I
Sbjct: 671 GSVQVNGS-------------VAYVPQLAWIQNLSLRNNILFNRPY----DAKLYQNVIE 713
Query: 545 QANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQS 604
+ L + P +T +G +G LSGGQKQR++LARA + I++LD+ SA+DS
Sbjct: 714 NCALVQDLESLPAEDRTEIGEKGINLSGGQKQRVSLARAVYQNAEIVLLDDPLSAVDSHV 773
Query: 605 EEVVAQSLQQRSARG----KTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ + +++ +A G KT + + H ++ ++H +VIVL + T++E G++ +L+
Sbjct: 774 GKHIFENVIS-TATGCLGTKTRVLLTHGLTYLKHCDQVIVL-KDETISEMGTYQELM 828
>7303902 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1344
Score = 134 bits (337), Expect = 5e-31
Identities = 137/540 (25%), Positives = 236/540 (43%), Gaps = 51/540 (9%)
Query: 158 VFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAG 217
+ ++ + N+ +L ++ RL D F N+ G +++R + D
Sbjct: 797 IIILSVIMNLSSSFLLFNIAKKASIRLHNTIFNRVTRADMHFFSINKHGSILNRFTKDMS 856
Query: 218 IVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLS 277
V + + L D V+Q + + I +LL P L + + Y +RNL
Sbjct: 857 QVDEVLPVVLVD----VMQ--IALWLAGIIIVIANVNPLLLVPTLMLSVIFY--HLRNLY 908
Query: 278 RQLQTSVGELTKVSEE--------QLSATKTIQAYCGEK---KEIHRYADEVRKVFHVGL 326
+ + + ++ L+ TI+A ++ KE Y D F + +
Sbjct: 909 LKTSRDLKRVEAINRSPVYSHLAASLNGLTTIRALDAQRVLEKEFDSYQDAHSSAFFMYI 968
Query: 327 KEALTSG----------------AFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSS 370
+ G +FF GN A + L++T S T +T+ S
Sbjct: 969 STSQAFGYCMNCICVIYISIITLSFFAFPP--GNGADVGLVITQVSHY-TKAVTITCQSP 1025
Query: 371 F-MMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKP---LIHPTIGKDPVTL-EN 425
F A+ EL A RV E +P L P K P T E
Sbjct: 1026 FGYPQAMGLIDMVQWGVRQTAELENTMTAVERVVEYESIEPEGMLEAPDDKKPPKTWPEQ 1085
Query: 426 KSIHFNHVKFSY-PTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGS 484
I F + Y P ++ + L+F ++P E V IVG +G GKS++ + L R
Sbjct: 1086 GEIIFKELNLRYTPNAKAENVLKSLSFVIQPREKVGIVGRTGAGKSSLINALFRL-SYTD 1144
Query: 485 GEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIG 544
G + + + R L RR + ++ QEP+LFSGT+ N+ P + +DE ++ +
Sbjct: 1145 GSVLIDTRDTRQMGLHDLRRQISIIPQEPVLFSGTMRYNLD---PFDEYSDE-KLWGCLE 1200
Query: 545 QANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQS 604
+ + +++ PDGL + + GT S GQ+Q + LARA L + IL++DEAT+ +D Q+
Sbjct: 1201 EVKLKEVVSDLPDGLASKISEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQT 1260
Query: 605 EEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSL 664
+ ++ +++ + R T ++IAHR+ TI S +V+V++ G V E GS +L+ DS +
Sbjct: 1261 DGLIQATIRSK-FRDCTVLTIAHRLHTIIDSDKVMVMDA-GRVVEFGSPYELMTKSDSKV 1318
Score = 97.8 bits (242), Expect = 5e-20
Identities = 62/245 (25%), Positives = 107/245 (43%), Gaps = 18/245 (7%)
Query: 413 HPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTV 472
+P + L +I +K + + +N ++PG V ++G +G GKS++
Sbjct: 435 NPPSNNNEADLLKSAISIRDLKAKWDPNSPDYTLSGINLEIKPGSVVAVIGLTGSGKSSL 494
Query: 473 ASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQEL 532
+L SG++++ L QE LFSGT+ NI + P
Sbjct: 495 IQAILGELKANSGQLQVNGS-------------LSYTSQESWLFSGTVRQNILFGQPM-- 539
Query: 533 VNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILI 592
D R + + + P T VG RG LSGGQK RI+LAR+ SI +
Sbjct: 540 --DSQRYEEVVKKCALERDFDLLPLRDNTIVGERGATLSGGQKARISLARSVYRKASIYL 597
Query: 593 LDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGS 652
LD+ SA+D+ + + RG T + + H+ + H ++++L +G + G
Sbjct: 598 LDDPLSAVDASVARHLFDQCVRGHLRGSTVVLVTHQEQFLPHVDQIVIL-ANGQIKALGD 656
Query: 653 FDKLI 657
++ L+
Sbjct: 657 YESLL 661
>CE23037 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1144
Score = 132 bits (333), Expect = 1e-30
Identities = 132/531 (24%), Positives = 233/531 (43%), Gaps = 31/531 (5%)
Query: 152 YTALGGV-FVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLIS 210
Y GG+ ++ ALA +L + R L + + A L +F D G +I+
Sbjct: 628 YAGFGGLEMLLLALA----FTVLTIGSLRASYGLHSPLIHALLVAPISFFDTTPTGRIIN 683
Query: 211 RLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVM----A 266
RLS D ++ K L D R Q + M+ + T + ++ A PL ++
Sbjct: 684 RLSRDLDVIDK-----LQDNIRMCTQTLLNACMILVLISISTPIFLVCAAPLILIYYFVM 738
Query: 267 LVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGL 326
+ Y R L R + + E + +I+A+ ++ + V K
Sbjct: 739 IYYIPTSRQLKRLESANRSPILSTIAESIHGASSIRAFDKTERTTTALSTNVDKFAQCRY 798
Query: 327 KEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXX 386
+++ +GN +L L+ T K +T G + YA+
Sbjct: 799 LSHMSNRWLATRLELLGNTCVLFASLSATLSTKYFGLTPGMAGLSVSYALTITEVLNICV 858
Query: 387 XXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKS-------IHFNHVKFSYPT 439
E+ + RV E +P I K +LEN+ I + Y
Sbjct: 859 RSVSEIESNIVSVERVNEYQKLEPEAPWRIEK---SLENEEKWPVKGKIELDGFSMRY-R 914
Query: 440 RPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNL 499
+ + ++++ + GE + ++G +G GKS++ L R + SG IK+ + I L
Sbjct: 915 KNLPLVLKNIDLKIEGGERIGVIGRTGSGKSSLTMALYRMIEGESGTIKIDDVEIDTIGL 974
Query: 500 RKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGL 559
+ R L ++ QEP++FSGT+ N+ P +D+ +I + +F L
Sbjct: 975 HQLRSKLIIIPQEPVVFSGTLRFNLD---PFNQYSDD-QIWNCLEICQLKQFAQEDDKTL 1030
Query: 560 QTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARG 619
+ G +S G++Q + L RA L I+ILDEAT+++D+ ++ +V ++++Q +
Sbjct: 1031 DRYIAEGGKNMSVGERQLLCLCRALLRGARIVILDEATASVDTVTDGIVQRAIRQHFPQ- 1089
Query: 620 KTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
TTISIAHR+ TI S R++VL+ G VAE + L+ PDS ++LL++
Sbjct: 1090 STTISIAHRLDTIVDSDRIVVLDA-GRVAEFDTPSNLLLNPDSLYSQLLNE 1139
Score = 103 bits (257), Expect = 9e-22
Identities = 109/485 (22%), Positives = 198/485 (40%), Gaps = 62/485 (12%)
Query: 206 GDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSF-ISWKL---TCVMMLLAPP 261
G++++ + D I+ SV L + Q + M++ + W C+M+L P
Sbjct: 34 GEILNHAAVDIEIIVHSVPY-LQNMWSVPFQVTLAMTMLAITLGWAAMAGVCIMILFIP- 91
Query: 262 LGVMALVYGKRIRNLSRQLQTSV-GELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRK 320
+ R LS+Q Q + E TK+S E L+ K ++ Y E+ + D++ +
Sbjct: 92 ----LNLCTSRFIKLSQQKQMKIKDERTKLSNEMLNGIKVVKLYAWEES----FEDQINR 143
Query: 321 VFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXX 380
+ +K + NV +L+ ++ + L+ +G + +++++
Sbjct: 144 LRAKEVK-------------MLRNVCILSRIVDVANAASPFLVAIGSFTCYVLWSPDENG 190
Query: 381 XXXXXXXXXXELMK-------------GAGAAARVFELNDRKPLIHPTIGKDPVTLENKS 427
+ ARV R+ L + + +
Sbjct: 191 LTPSVAFVALTIFNQLRQPMRMVANLINTLVQARVSNKRLRQFLNDEEMERKTEVALGNA 250
Query: 428 IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEI 487
I F + ++ + +DL+ T++PG+ + IVG GGGKS++ S +L + G +
Sbjct: 251 IVFKNASLNWKGPQNPPVLKDLSATIKPGQLIAIVGSVGGGKSSLLSAVLDEMVLLDGRV 310
Query: 488 KLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQAN 547
K+G + V Q +F+ TI +NI + EL N + +G
Sbjct: 311 KVGGS-------------IAYVPQHSWIFNKTIKENILFG--NELSN--YFYDQVVGSCQ 353
Query: 548 CTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEV 607
+F G T VG G LSGGQK RI+LARA D I +LD+ SA+D+
Sbjct: 354 LKTDFRHFQQGENTMVGENGITLSGGQKARISLARAVYQDKDIYLLDDPLSAVDAHVGRA 413
Query: 608 VAQSL--QQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLN 665
+ + R KT + + H + ++ + V+ G + + GSF+ IA D
Sbjct: 414 LFDKVIGPDGLLRSKTRVLVTHNLQYTKYVDTIYVI-EDGQIVQHGSFED-IAYVDGPFG 471
Query: 666 KLLSK 670
+L S+
Sbjct: 472 RLWSE 476
>Hs4507317 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1581
Score = 132 bits (331), Expect = 2e-30
Identities = 126/512 (24%), Positives = 224/512 (43%), Gaps = 43/512 (8%)
Query: 171 VILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDG 230
V ++ TG ++ RL + + F + +G +++R SSD + + + L
Sbjct: 1083 VTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECL 1142
Query: 231 TRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQ----TSVGE 286
+R+ + ++S++ T V ++ PL V+ K R SR LQ T+
Sbjct: 1143 SRSTLLCVSALAVISYV----TPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLP 1198
Query: 287 LTKVSEEQLSATKTIQAYCGE---KKEIHRYADE--VRKVFHVGLKEALTSGAFFGVTGF 341
L E + TI+A+ E ++++ Y D + +F L +
Sbjct: 1199 LLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRM-----EY 1253
Query: 342 VGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAAR 401
+G +L +T S ++ G + + YA+ ++ GA R
Sbjct: 1254 IGACVVLIAAVTSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMELQLGAVKR 1313
Query: 402 VF-----ELNDRKPLIHPTI------GKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLN 450
+ E + L+ P++ + + ++N S V++ +P + + +N
Sbjct: 1314 IHGLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLS-----VRYDSSLKP---VLKHVN 1365
Query: 451 FTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQ 510
+ PG+ + I G +G GKS+ + R D G I + +IR L L ++
Sbjct: 1366 ALISPGQKIGICGRTGSGKSSFSLAFFRMVDTFEGHIIIDGIDIRKLPLHTLPSRLSIIL 1425
Query: 511 QEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQL 570
Q+P+LFSGTI N+ P+ +D T + A+ A + P GL + G
Sbjct: 1426 QDPVLFSGTIRFNLD---PERKCSDST-LWEALEIAQLKLVVKALPGGLDAIITEGGENF 1481
Query: 571 SGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVS 630
S GQ+Q LARAF+ SI I+DEAT+++D +E ++ Q + + +T ++IAHRV
Sbjct: 1482 SQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENIL-QKVVMTAFADRTVVTIAHRVH 1540
Query: 631 TIQHSSRVIVLNRHGTVAETGSFDKLIAIPDS 662
TI + VIVL R G + E +KL++ DS
Sbjct: 1541 TILSADLVIVLKR-GAILEFDKPEKLLSRKDS 1571
Score = 76.6 bits (187), Expect = 1e-13
Identities = 62/221 (28%), Positives = 105/221 (47%), Gaps = 24/221 (10%)
Query: 450 NFTVR--PGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEI--------KLGND------N 493
N T+R G+ IVG G GKS++ L SG + ++G D
Sbjct: 698 NITIRIPRGQLTMIVGQVGCGKSSLLLAALGEMQKVSGAVFWSSLPDSEIGEDPSPERET 757
Query: 494 IRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLA 553
D ++RK R + Q+P L + T+ +NI + P ++ R I + +
Sbjct: 758 ATDLDIRK-RGPVAYASQKPWLLNATVEENIIFESPF----NKQRYKMVIEACSLQPDID 812
Query: 554 NFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQS-- 611
P G QT +G RG LSGGQ+QRI++ARA +++ LD+ SALD + + Q+
Sbjct: 813 ILPHGDQTQIGERGINLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGI 872
Query: 612 LQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGS 652
L+ +T + + H++ + H+ +I + + GT+ G+
Sbjct: 873 LELLRDDKRTVVLVTHKLQYLPHADWIIAM-KDGTIQREGT 912
>Hs10947122 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1549
Score = 132 bits (331), Expect = 2e-30
Identities = 128/475 (26%), Positives = 222/475 (45%), Gaps = 37/475 (7%)
Query: 199 FLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLL 258
F D +G +++R S+D I+ + + L TR+ + GM+S+ T V ++
Sbjct: 1083 FFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYA----TPVFLVA 1138
Query: 259 APPLGVMALVYGKRIRNLSRQLQ-----TSVGELTKVSEEQLSATKTIQAYCGEKKEIHR 313
PLGV K R S+ LQ T + L SE T TI+A+ E + R
Sbjct: 1139 LLPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLT-TIRAFRHETRFKQR 1197
Query: 314 YAD--EVRKVFHVGLKEALTSGAFFGV-TGFVGN-VALLALLLTGTSMIKTGLMTVGDLS 369
+ + + ++ L A + V T ++G + L A + + + +GL+ +G
Sbjct: 1198 MLELTDTNNIAYLFLSAA---NRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLG--- 1251
Query: 370 SFMMYAVXXXXXXXXXXXXXXELMKGAGAAARV-----FELNDRKPLIHPTIGKDPVTLE 424
++YA+ +L GA +V E + + + P+ + E
Sbjct: 1252 --LLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQE 1309
Query: 425 NK-SIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG 483
+ IH V++ +P + + + ++PG+ V I G +G GKS+++ R DI
Sbjct: 1310 GEIKIHDLCVRYENNLKP---VLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIF 1366
Query: 484 SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAI 543
G+I + +I L R L ++ Q+P+LFSG+I N+ P+ D+ R+ A+
Sbjct: 1367 DGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLD---PECKCTDD-RLWEAL 1422
Query: 544 GQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQ 603
A + + P GL V G S GQ+Q LARAF+ SILI+DEAT+++D
Sbjct: 1423 EIAQLKNMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMA 1482
Query: 604 SEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
+E ++ Q + + +T +++AHRV TI + VIV+ R G + E + + L+A
Sbjct: 1483 TENIL-QKVVMTAFADRTVVTMAHRVHTILTADLVIVMKR-GNILEYDTPESLLA 1535
Score = 77.0 bits (188), Expect = 9e-14
Identities = 58/211 (27%), Positives = 101/211 (47%), Gaps = 11/211 (5%)
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRD--FNLRKYRRL 505
+++ + G+ IVG G GKS++ +L G++ N N + F + R
Sbjct: 690 NIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEATRSRNR 749
Query: 506 LGVVQ--QEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTV 563
V Q+P L + T+ +NIT+ P ++ R + + P G QT +
Sbjct: 750 YSVAYAAQKPWLLNATVEENITFGSPF----NKQRYKAVTDACSLQPDIDLLPFGDQTEI 805
Query: 564 GPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQS--LQQRSARGKT 621
G RG LSGGQ+QRI +ARA + +I+ LD+ SALD + + Q L+ +T
Sbjct: 806 GERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRT 865
Query: 622 TISIAHRVSTIQHSSRVIVLNRHGTVAETGS 652
+ + H++ + H+ +I + + G+V G+
Sbjct: 866 LVLVTHKLQYLTHADWIIAM-KDGSVLREGT 895
>7298738 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1014
Score = 131 bits (329), Expect = 4e-30
Identities = 127/481 (26%), Positives = 219/481 (45%), Gaps = 35/481 (7%)
Query: 188 TMKAALEQDATFLDH-NRVGDLISRLSSDAGIVSKSVTQNLSDGTRA--VIQGFVGFGMM 244
TM + + A + H N G +++R + D G V + + + D + I G +G +
Sbjct: 516 TMFQGVSRTALYFFHANPSGRILNRFAMDLGQVDEILPAVMLDCIQIFLTISGIIGVLCI 575
Query: 245 SFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAY 304
+ + + + M LA + Y R+L R + + L+ TI+A
Sbjct: 576 TNPWYLINTITMFLA--FHFLRTFYLSTSRDLKRLEAIARSPMYSHFSATLNGLSTIRAM 633
Query: 305 CGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMT 364
+ Y D + + G L++ FG + VA + + +T S +
Sbjct: 634 EAQDLLTKEY-DNYQDIHSSGYYTFLSTNRAFGYYLDLFCVAYV-ISVTLMSYFNPPVDN 691
Query: 365 VGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFEL------------NDRKPLI 412
G + + A+ EL + RV E +D+KP +
Sbjct: 692 PGQIGLVITQAMSMTGTVQWGMRQSAELENSMTSVERVLEYRHLEAEGEFESPDDKKPPM 751
Query: 413 H-PTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKST 471
+ P G ++ E S+ +N P + + LNF + P E + IVG +G GKS+
Sbjct: 752 NWPQEGL--ISAEQLSLRYN------PDPKADRVLKSLNFIIMPREKIGIVGRTGAGKSS 803
Query: 472 VASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQE 531
+ + L R G + + N +I L R + ++ QEP+LFSGT+ N+ P E
Sbjct: 804 LINALFRL-SYNEGSLVIDNTDILGIGLHDLRSKISIIPQEPVLFSGTLRCNLD---PFE 859
Query: 532 LVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSIL 591
DE ++ A+ + + ++ P+GL++ V G+ S GQ+Q + LARA L + IL
Sbjct: 860 QYADE-KLWEALEEVHLKDEVSELPNGLESVVAEGGSNYSVGQRQLVCLARAILRENRIL 918
Query: 592 ILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETG 651
++DEAT+ +D Q++ ++ QS +R R T ++IAHR++TI S RV+VL+ GT+ E G
Sbjct: 919 VMDEATANVDPQTDALI-QSTIRRKFRDCTVLTIAHRLNTIIDSDRVMVLDA-GTLVEFG 976
Query: 652 S 652
S
Sbjct: 977 S 977
Score = 97.4 bits (241), Expect = 6e-20
Identities = 90/391 (23%), Positives = 168/391 (42%), Gaps = 62/391 (15%)
Query: 269 YGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKE 328
+G+ I L R +S+ ++ + LS T+ R A V + V +
Sbjct: 20 FGRLIERLRRSEMSSIRKVNYIRGTLLSFEITLS----------RIAIFVSLLGFVLMGG 69
Query: 329 ALTSGAFFGVTGFVGNV--ALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXX 386
LT+ F VT F + + +G S ++T+ + FMM +
Sbjct: 70 ELTAERAFSVTAFYNILRRTVCKFFPSGMSQFAEMMVTLRRIKGFMMRSETEALY----- 124
Query: 387 XXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIF 446
+KG G ++FE G+ V L++ +NH +
Sbjct: 125 ------LKG-GQTNKLFE------------GEPLVKLQSFQARWNHDHVE-------PVL 158
Query: 447 EDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLL 506
E++N ++ P + V ++GP G GKS++ +L SG++K+ D +
Sbjct: 159 ENINISLSPPQLVAVIGPVGSGKSSLIQAILGELPGESGKLKVQGD-------------I 205
Query: 507 GVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPR 566
QEP LF+ ++ DNI + +P D+ R I + G +T VG R
Sbjct: 206 SYASQEPWLFNASVRDNILFGLPM----DKHRYRNVIRNCALERDF-ELLHGDRTFVGER 260
Query: 567 GTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIA 626
G LSGGQ+ RI+LARA +LD+ SA+D+ + + + R K I +
Sbjct: 261 GASLSGGQRARISLARAVYRQADTYLLDDPLSAVDTHVGRHLFEECMRGFLRDKLVILVT 320
Query: 627 HRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
H++ ++H+ ++++++ G ++ G++++++
Sbjct: 321 HQLQFLEHADLIVIMDK-GKISAVGTYEEML 350
>Hs5032135 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1549
Score = 129 bits (325), Expect = 1e-29
Identities = 127/485 (26%), Positives = 224/485 (46%), Gaps = 37/485 (7%)
Query: 199 FLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLL 258
F D +G +++R S+D I+ + + L TR+ + GM+S+ T V ++
Sbjct: 1083 FFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYA----TPVFLVA 1138
Query: 259 APPLGVMALVYGKRIRNLSRQLQ-----TSVGELTKVSEEQLSATKTIQAYCGEKKEIHR 313
PLGV K R S+ LQ T + L SE T TI+A+ E + R
Sbjct: 1139 LLPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLT-TIRAFRHETRFKQR 1197
Query: 314 YAD--EVRKVFHVGLKEALTSGAFFGV-TGFVGN-VALLALLLTGTSMIKTGLMTVGDLS 369
+ + + ++ L A + V T ++G + L A + + + +GL+ +G
Sbjct: 1198 MLELTDTNNIAYLFLSAA---NRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLG--- 1251
Query: 370 SFMMYAVXXXXXXXXXXXXXXELMKGAGAAARV-----FELNDRKPLIHPTIGKDPVTLE 424
++YA+ +L GA +V E + + + P+ + E
Sbjct: 1252 --LLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQE 1309
Query: 425 NK-SIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG 483
+ IH V++ +P + + + ++PG+ V I G +G GKS+++ R DI
Sbjct: 1310 GEIKIHDLCVRYENNLKP---VLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIF 1366
Query: 484 SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAI 543
G+I + +I L R L ++ Q+P+LFSG+I N+ P+ D+ R+ A+
Sbjct: 1367 DGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLD---PECKCTDD-RLWEAL 1422
Query: 544 GQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQ 603
A + + P GL V G S GQ+Q LARAF+ SILI+DEAT+++D
Sbjct: 1423 EIAQLKNMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMA 1482
Query: 604 SEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSS 663
+E ++ Q + + +T +++AHRVS+I + V+V + G + E + L A +
Sbjct: 1483 TENIL-QKVVMTAFADRTVVTMAHRVSSIMDAGLVLVFS-EGILVECDTVPNLFAHKNGP 1540
Query: 664 LNKLL 668
+ L+
Sbjct: 1541 FSTLV 1545
Score = 77.0 bits (188), Expect = 9e-14
Identities = 58/211 (27%), Positives = 101/211 (47%), Gaps = 11/211 (5%)
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRD--FNLRKYRRL 505
+++ + G+ IVG G GKS++ +L G++ N N + F + R
Sbjct: 690 NIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEATRSRNR 749
Query: 506 LGVVQ--QEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTV 563
V Q+P L + T+ +NIT+ P ++ R + + P G QT +
Sbjct: 750 YSVAYAAQKPWLLNATVEENITFGSPF----NKQRYKAVTDACSLQPDIDLLPFGDQTEI 805
Query: 564 GPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQS--LQQRSARGKT 621
G RG LSGGQ+QRI +ARA + +I+ LD+ SALD + + Q L+ +T
Sbjct: 806 GERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRT 865
Query: 622 TISIAHRVSTIQHSSRVIVLNRHGTVAETGS 652
+ + H++ + H+ +I + + G+V G+
Sbjct: 866 LVLVTHKLQYLTHADWIIAM-KDGSVLREGT 895
>Hs10947124 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1513
Score = 129 bits (325), Expect = 1e-29
Identities = 127/485 (26%), Positives = 224/485 (46%), Gaps = 37/485 (7%)
Query: 199 FLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLL 258
F D +G +++R S+D I+ + + L TR+ + GM+S+ T V ++
Sbjct: 1047 FFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYA----TPVFLVA 1102
Query: 259 APPLGVMALVYGKRIRNLSRQLQ-----TSVGELTKVSEEQLSATKTIQAYCGEKKEIHR 313
PLGV K R S+ LQ T + L SE T TI+A+ E + R
Sbjct: 1103 LLPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLT-TIRAFRHETRFKQR 1161
Query: 314 YAD--EVRKVFHVGLKEALTSGAFFGV-TGFVGN-VALLALLLTGTSMIKTGLMTVGDLS 369
+ + + ++ L A + V T ++G + L A + + + +GL+ +G
Sbjct: 1162 MLELTDTNNIAYLFLSAA---NRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLG--- 1215
Query: 370 SFMMYAVXXXXXXXXXXXXXXELMKGAGAAARV-----FELNDRKPLIHPTIGKDPVTLE 424
++YA+ +L GA +V E + + + P+ + E
Sbjct: 1216 --LLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQE 1273
Query: 425 NK-SIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG 483
+ IH V++ +P + + + ++PG+ V I G +G GKS+++ R DI
Sbjct: 1274 GEIKIHDLCVRYENNLKP---VLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIF 1330
Query: 484 SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAI 543
G+I + +I L R L ++ Q+P+LFSG+I N+ P+ D+ R+ A+
Sbjct: 1331 DGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLD---PECKCTDD-RLWEAL 1386
Query: 544 GQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQ 603
A + + P GL V G S GQ+Q LARAF+ SILI+DEAT+++D
Sbjct: 1387 EIAQLKNMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMA 1446
Query: 604 SEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSS 663
+E ++ Q + + +T +++AHRVS+I + V+V + G + E + L A +
Sbjct: 1447 TENIL-QKVVMTAFADRTVVTMAHRVSSIMDAGLVLVFS-EGILVECDTVPNLFAHKNGP 1504
Query: 664 LNKLL 668
+ L+
Sbjct: 1505 FSTLV 1509
Score = 77.0 bits (188), Expect = 9e-14
Identities = 58/211 (27%), Positives = 101/211 (47%), Gaps = 11/211 (5%)
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRD--FNLRKYRRL 505
+++ + G+ IVG G GKS++ +L G++ N N + F + R
Sbjct: 654 NIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEATRSRNR 713
Query: 506 LGVVQ--QEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTV 563
V Q+P L + T+ +NIT+ P ++ R + + P G QT +
Sbjct: 714 YSVAYAAQKPWLLNATVEENITFGSPF----NKQRYKAVTDACSLQPDIDLLPFGDQTEI 769
Query: 564 GPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQS--LQQRSARGKT 621
G RG LSGGQ+QRI +ARA + +I+ LD+ SALD + + Q L+ +T
Sbjct: 770 GERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRT 829
Query: 622 TISIAHRVSTIQHSSRVIVLNRHGTVAETGS 652
+ + H++ + H+ +I + + G+V G+
Sbjct: 830 LVLVTHKLQYLTHADWIIAM-KDGSVLREGT 859
>At2g34660 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1623
Score = 129 bits (325), Expect = 1e-29
Identities = 132/533 (24%), Positives = 241/533 (44%), Gaps = 42/533 (7%)
Query: 160 VVGALANVGRIVILKVTGERLVA-------RLRTRTMKAALEQDATFLDHNRVGDLISRL 212
++ AL + G++++ L+ +L + + L +F N +G +I+R
Sbjct: 961 LIYALLSFGQVLVTLTNSYWLIMSSLYAAKKLHDNMLHSILRAPMSFFHTNPLGRIINRF 1020
Query: 213 SSDAGIVSKSVTQ--NLSDG-TRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVY 269
+ D G + ++V N+ G ++ V G++S +S L +M LL G L Y
Sbjct: 1021 AKDLGDIDRTVAVFVNMFMGQVSQLLSTVVLIGIVSTLS--LWAIMPLLVLFYGAY-LYY 1077
Query: 270 GKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEA 329
R + R S + E L+ TI+AY K R AD + ++
Sbjct: 1078 QNTAREVKRMDSISRSPVYAQFGEALNGLSTIRAY----KAYDRMADINGRSMDNNIRFT 1133
Query: 330 LTSGAFFGVTGFVG----NVALLALLLTGT-SMIKTG--------LMTVGDLSSFMMYAV 376
L + G ++G + L + LT + ++++ G T+G L S+ +
Sbjct: 1134 LVN---MGANRWLGIRLETLGGLMIWLTASFAVMQNGRAENQQAFASTMGLLLSYALNIT 1190
Query: 377 XXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFS 436
+ E+ P + P + SI F V
Sbjct: 1191 SLLTGVLRLASLAENSLNAVERVGNYIEIPPEAPPVIENNRPPPGWPSSGSIKFEDVVLR 1250
Query: 437 YPTRPQ-HHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIR 495
Y RPQ + ++F + P + V IVG +G GKS++ + L R ++ G I + + ++
Sbjct: 1251 Y--RPQLPPVLHGVSFFIHPTDKVGIVGRTGAGKSSLLNALFRIVEVEKGRILIDDCDVG 1308
Query: 496 DFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANF 555
F L R++LG++ Q P+LFSGT+ N+ P ND + ++ +A+ +
Sbjct: 1309 KFGLMDLRKVLGIIPQSPVLFSGTVRFNLD---PFGEHND-ADLWESLERAHLKDTIRRN 1364
Query: 556 PDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQR 615
P GL V G S GQ+Q ++L+RA L IL+LDEAT+A+D +++ ++ +++++
Sbjct: 1365 PLGLDAEVSEAGENFSVGQRQLLSLSRALLRRSKILVLDEATAAVDVRTDALIQKTIRE- 1423
Query: 616 SARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLL 668
+ T + IAHR++TI +++VL+ G V E S + L++ SS +K++
Sbjct: 1424 EFKSCTMLIIAHRLNTIIDCDKILVLD-SGRVQEFSSPENLLSNEGSSFSKMV 1475
Score = 97.4 bits (241), Expect = 6e-20
Identities = 69/237 (29%), Positives = 114/237 (47%), Gaps = 17/237 (7%)
Query: 420 PVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRY 479
P+ +I + FS+ ++ ++N V G V +VG +G GK+++ S +L
Sbjct: 606 PIEPGEPAISIRNGYFSWDSKGDRPTLSNINLDVPLGSLVAVVGSTGEGKTSLISAIL-- 663
Query: 480 YDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRI 539
GE+ +D I R + V Q +F+ T+ DNI + P D +
Sbjct: 664 -----GELPATSDAIVTL-----RGSVAYVPQVSWIFNATVRDNILFGSPF----DREKY 709
Query: 540 SRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSA 599
RAI + L P G T +G RG +SGGQKQR+++ARA + + I D+ SA
Sbjct: 710 ERAIDVTSLKHDLELLPGGDLTEIGERGVNISGGQKQRVSMARAVYSNSDVYIFDDPLSA 769
Query: 600 LDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
LD+ + V + +R KT + + +++ + R IVL GTV E G++++L
Sbjct: 770 LDAHVGQQVFEKCIKRELGQKTRVLVTNQLHFLSQVDR-IVLVHEGTVKEEGTYEEL 825
>At2g07680 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1146
Score = 129 bits (325), Expect = 1e-29
Identities = 127/524 (24%), Positives = 225/524 (42%), Gaps = 33/524 (6%)
Query: 160 VVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIV 219
++ ++ + R G + + + + F D G +++R SSD +
Sbjct: 637 IINSILTLVRAFSFAFGGLKAAVHVHNALISKLINAPTQFFDQTPSGRILNRFSSDLYTI 696
Query: 220 SKSVTQNLSDGTRAVIQGFVGF-GMMSFISWKLTCVMMLLAPPLGV---MALVYGKRIRN 275
S+ L+ ++ FVG G++ +S+ ++LL P + + + Y R
Sbjct: 697 DDSLPFILN----ILLANFVGLLGIIVVLSYVQVLFLLLLLPFWYIYSKLQVFYRSTSRE 752
Query: 276 LSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAF 335
L R S + E L + TI+A+ E+ + R+ + + E + S
Sbjct: 753 LRRLDSVSRSPIYASFTETLDGSSTIRAFKSEEHFVGRFIEHLTLYQRTSYSEIIASLWL 812
Query: 336 FGVTGFVGN-----VALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXX 390
+G+ VA++A+L +G + T G + + YA
Sbjct: 813 SLRLQLLGSMIVLFVAVMAVLGSGGNF-PISFGTPGLVGLALSYAAPLVSLLGSLLTSFT 871
Query: 391 ELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENK-----SIHFNHVKFSY-PTRPQHH 444
E K + RV + D + P +L +K + F++V Y T P
Sbjct: 872 ETEKEMVSVERVLQYMD----VPQEEVSGPQSLSDKWPVHGLVEFHNVTMRYISTLPP-- 925
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
++FT++ G HV ++G +G GKS++ + L R + SGEI + NI +R+ R
Sbjct: 926 ALTQISFTIQGGMHVGVIGRTGAGKSSILNALFRLTPVCSGEILVDGKNISHLPIRELRS 985
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
L VV Q P LF G++ DN+ P L +++ RI + + K GL + V
Sbjct: 986 CLAVVPQSPFLFQGSLRDNLD---PLGL-SEDWRIWEILDKCK-VKAAVESVGGLDSYVK 1040
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
G S GQ+Q + LARA L IL LDE T+ +D + ++ ++ +G T I+
Sbjct: 1041 ESGCSFSVGQRQLLCLARALLKSSKILCLDECTANIDVHTASLLHNTISS-ECKGVTVIT 1099
Query: 625 IAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLL 668
IAHR+ST+ +++L+R G + E G L+ S+ + +
Sbjct: 1100 IAHRISTVVDLDSILILDR-GILVEQGKPQHLLQDDSSTFSSFV 1142
Score = 72.8 bits (177), Expect = 2e-12
Identities = 62/221 (28%), Positives = 94/221 (42%), Gaps = 33/221 (14%)
Query: 444 HIFEDLNFTVRP-------GEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRD 496
++ ED N T++ G V ++G G GK+++ + LL G I L
Sbjct: 321 NVEEDYNLTIKQVSLRVPKGSFVAVIGEVGSGKTSLLNSLLGEMRCVHGSILLNGS---- 376
Query: 497 FNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFP 556
+ V Q P L SGT+ +NI + P D R + ++
Sbjct: 377 ---------VAYVPQVPWLLSGTVRENILFGKPF----DSKRYFETLSACALDVDISLMV 423
Query: 557 DGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRS 616
G +G +G LSGGQ+ R ALARA + +LD+ SA+DSQ V + QR+
Sbjct: 424 GGDMACIGDKGLNLSGGQRARFALARAVYHGSDMYLLDDVLSAVDSQ----VGCWILQRA 479
Query: 617 ARG-----KTTISIAHRVSTIQHSSRVIVLNRHGTVAETGS 652
G KT + H + S+ +IV+ G V +GS
Sbjct: 480 LLGPLLNKKTRVMCTHNIQVSNLSTHMIVVMDKGKVNWSGS 520
>At3g21250 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1305
Score = 128 bits (322), Expect = 3e-29
Identities = 131/529 (24%), Positives = 226/529 (41%), Gaps = 24/529 (4%)
Query: 153 TALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMK----AALEQDATFLDHNRVGDL 208
T L GV+ + + + G + +T L + A + F D VG +
Sbjct: 775 TMLIGVYSIISTLSAGFVYARAITTAHLGLKASKAFFSGFTNAVFKAPMLFFDSTPVGRI 834
Query: 209 ISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALV 268
++R SSD ++ V ++ +M++++W++ + +L V+
Sbjct: 835 LTRASSDLNVLDYDVPFAFIFVVAPAVELTAALLIMTYVTWQVIIIALLALAATKVVQDY 894
Query: 269 YGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEV-RKVFHVGLK 327
Y R L R T+ + + E TI+A+ ++ Y + V L
Sbjct: 895 YLASARELIRINGTTKAPVMNYAAETSLGVVTIRAFGTAERFFKNYLNLVDADAVLFFLS 954
Query: 328 EALTSGAFFGVTGFVGNVALL--ALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXX 385
A + + NV L ALLL +I G + G + + YA+
Sbjct: 955 NAAMEWVILRIET-LQNVTLFTCALLLI---LIPKGYIAPGLVGLSLSYALTLTQTQVFL 1010
Query: 386 XXXXXELMKGAGAAARV---FELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSY-PTRP 441
L + R+ + + P I N +IH +K Y P P
Sbjct: 1011 TRWYCTLSNSIISVERIKQYMNIPEEPPAIIDDKRPPSSWPSNGTIHLQELKIRYRPNAP 1070
Query: 442 QHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRK 501
+ + ++ T R G V +VG +G GKST+ S L R + SG I + +I L+
Sbjct: 1071 L--VLKGISCTFREGTRVGVVGRTGSGKSTLISALFRLVEPASGCILIDGIDISKIGLKD 1128
Query: 502 YRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQT 561
R L ++ QEP LF G I N+ P + +D+ I +A+ + ++N P+ L +
Sbjct: 1129 LRMKLSIIPQEPTLFRGCIRTNLD---PLGVYSDD-EIWKALEKCQLKTTISNLPNKLDS 1184
Query: 562 TVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKT 621
+V G S GQ+Q L R L IL+LDEAT+++DS ++ ++ + +++ A T
Sbjct: 1185 SVSDEGENWSVGQRQLFCLGRVLLKRNKILVLDEATASIDSATDAIIQRIIREEFA-DCT 1243
Query: 622 TISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
I++AHRV T+ S V+VL+ G + E KL+ DS +KL+++
Sbjct: 1244 VITVAHRVPTVIDSDMVMVLS-FGDLVEYNEPSKLME-TDSYFSKLVAE 1290
Score = 116 bits (291), Expect = 1e-25
Identities = 111/493 (22%), Positives = 212/493 (42%), Gaps = 42/493 (8%)
Query: 176 TGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSK---------SVTQN 226
+G R+ + L K L+ + + G++++ ++ DA + + S++
Sbjct: 189 SGMRIRSALMVAAYKKQLKLSSLGRKRHSSGEIVNYIAVDAYRMGEFLWWFHSGWSLSLQ 248
Query: 227 LSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGE 286
L T AV+ G VG G + L C G++ L + K ++N Q + +
Sbjct: 249 LLLST-AVLFGVVGAGAFPGLILLLLC---------GLLNLPFAKMLQNCQTQFMIAQDK 298
Query: 287 LTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVA 346
+ + E L++ K I+ E E + + R L +A + AF ++
Sbjct: 299 RLRSTSEILNSMKVIKLQSWED-EFKKKIESCRDDEFTWLAKAQLTKAFGSFLYWMSPTI 357
Query: 347 LLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARV--FE 404
+ +++ G +++K+ + + + + +++G + R+ F
Sbjct: 358 VSSVVFLGCALLKSAPLNASTIFTVLATLRVMSEPVKIIPDAISAIIQGNVSFQRLNNFL 417
Query: 405 LNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGP 464
L+D + I + + ++ F + + +++ ++ G+ V + GP
Sbjct: 418 LDDELKM--DEIERSGLDASGTAVDIQVGNFGWEPETKIPTLRNIHLEIKHGQKVAVCGP 475
Query: 465 SGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNI 524
G GKS++ +L GEI + ++ F Y V Q + SGTI DNI
Sbjct: 476 VGAGKSSLLHAVL-------GEIPKVSGTVKVFGSIAY------VSQTSWIQSGTIRDNI 522
Query: 525 TYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAF 584
Y P E R + AI K + F G T +G RG LSGGQKQRI LARA
Sbjct: 523 LYGKPME----SRRYNAAIKACALDKDMNGFGHGDLTEIGQRGINLSGGQKQRIQLARAV 578
Query: 585 LLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRH 644
D + +LD+ SA+D+ + V+ + S + KT I + H+V + +++V+
Sbjct: 579 YADADVYLLDDPFSAVDAHTAGVLFHKCVEDSLKEKTVILVTHQVEFLSEVDQILVM-EE 637
Query: 645 GTVAETGSFDKLI 657
GT+ ++G +++L+
Sbjct: 638 GTITQSGKYEELL 650
>CE26370 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1525
Score = 128 bits (321), Expect = 3e-29
Identities = 124/509 (24%), Positives = 233/509 (45%), Gaps = 42/509 (8%)
Query: 171 VILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDG 230
+IL + R L + + F D +G +++R+ D +++ + L D
Sbjct: 1028 IILTIGVLRASRILHAGLLGNIMRSPMAFFDVTPIGRILNRIGKDI----EAIDRTLPDV 1083
Query: 231 TRAVIQGFVGFGMMSFISWKLTCVMMLLAPP-----LGVMALVYGKRIR---NLSRQLQ- 281
R + M+ + T V+++ A P +++++Y +R + SRQL+
Sbjct: 1084 IRHM--------SMTIFNVVATLVVIMWATPWAGIAFAILSVIYFIVLRFYISTSRQLKR 1135
Query: 282 ---TSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGV 338
S + +E + +I+A+ G + + + + ++ + + V
Sbjct: 1136 LESASRSPIYSHFQESIQGASSIRAF-GVVDNFIKQSQQRVDDHLIAYYPSIVANRWLAV 1194
Query: 339 T-GFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAG 397
VGN+ +L+ + ++ G + + YA+ EL
Sbjct: 1195 RLEMVGNLIVLSAAGAAVYFRDSPGLSAGLVGLSVSYALNITQTLNWAVRMTSELETNIV 1254
Query: 398 AAARVFELNDRKPLIHPTIGKDPVTLENKSI----HFNHVKFSYPTRPQHH-IFEDLNFT 452
+ R+ E + PT G + L KS + FS RP + ++
Sbjct: 1255 SVERIKEYT-----VTPTEGNNSRRLAAKSWPEKGEISIKNFSVRYRPGLDLVLHGISAH 1309
Query: 453 VRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQE 512
+ P E V IVG +G GKS++ L R + G I++ NI + L + R L +V Q+
Sbjct: 1310 IAPSEKVGIVGRTGAGKSSLTLALFRIIEADGGSIEIDGINIANLQLEQLRSCLTIVPQD 1369
Query: 513 PMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSG 572
P+LFSGT+ N+ P +D +++ A+ A+ F+ + DGL+ + G LS
Sbjct: 1370 PVLFSGTMKMNLD---PFSAYSD-SQVWEALENAHLKPFVKSLQDGLEHKISEGGENLSV 1425
Query: 573 GQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTI 632
GQ+Q I LARA L +L+LDEA +A+D +++ ++ ++++++ + T ++IAHR++T+
Sbjct: 1426 GQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLIQKTIREQ-FKECTVLTIAHRLNTV 1484
Query: 633 QHSSRVIVLNRHGTVAETGSFDKLIAIPD 661
S R++VL++ G VAE S L+A PD
Sbjct: 1485 MDSDRLLVLDK-GRVAEFDSPKNLLANPD 1512
Score = 103 bits (256), Expect = 1e-21
Identities = 68/215 (31%), Positives = 120/215 (55%), Gaps = 25/215 (11%)
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLG 507
+++F ++ G+ V IVG G GKS++ LL + SG +++ N NI
Sbjct: 633 EISFKIQKGQLVAIVGKVGSGKSSLLHALLGEMNKLSGSVQI-NGNI------------A 679
Query: 508 VVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCT--KFLANFPDGLQTTVGP 565
V Q+ + + ++ +NI + P +L N E + NC + LAN P G +T +G
Sbjct: 680 YVPQQAWIQNMSLRNNILFNKPYDLENYEDVVK------NCALKEDLANLPAGDRTEIGE 733
Query: 566 RGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSA---RGKTT 622
+G LSGGQKQR++LARA +P I++LD+ SA+DS + + +++ S KT
Sbjct: 734 KGINLSGGQKQRVSLARAVYQNPDIILLDDPLSAVDSHVGKHIFENVISSSTGCLASKTR 793
Query: 623 ISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ + H ++ ++H ++IVL + GT++E G++ +L+
Sbjct: 794 VLVTHGLTYLKHCDQLIVL-KEGTISELGTYQELL 827
>CE23650 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1427
Score = 127 bits (320), Expect = 4e-29
Identities = 127/512 (24%), Positives = 224/512 (42%), Gaps = 40/512 (7%)
Query: 149 TQFYTALGGV-FVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGD 207
T FY A+ V VV ++ + + + RL R +A + +F D G
Sbjct: 834 TGFYAAVYLVALVVLTISGLFKACVFVKVSLTAATRLHDRMFQAVIHGATSFFDSTPTGR 893
Query: 208 LISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMAL 267
+++R S D + L +Q + + + +L A PL V+ +
Sbjct: 894 ILNRFSKDMD----EIDVKLPFTAEVFLQNMITCLGFLVVITSVFPYFLLFAIPLFVVFV 949
Query: 268 VYGK----RIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFH 323
V+ IRNL R S L L TI + ++ +R+ + ++K H
Sbjct: 950 VFVSCFRAGIRNLKRSEHISRSPLYDHVSASLEGITTIHTF----QQSNRFLEVLKK--H 1003
Query: 324 VGLKEALTSGAFFGVTGFVGNVA----LLALLLTGT----SMIKTGLMTVGDLSSFMMYA 375
+ SGA F + +A LL +++T +++ TG ++ D + +A
Sbjct: 1004 LDCN----SGAIFMFQSAMRWLAVWLDLLVVVMTAIVALLTVMLTGTVSPADAGMAIAFA 1059
Query: 376 VXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLE-----NKSIHF 430
V EL + RV D P + + +E N I+F
Sbjct: 1060 VQMSGIFQFAVRTQTELEAKMTSVERVSYYADNIPEDGEWNTRQGLDIESSWPANGQINF 1119
Query: 431 NHVKFSYPTRPQHHI-FEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKL 489
+ V Y R H + D+ F ++ GE V I+G +G GKS++A+L+ R Y + +G I +
Sbjct: 1120 SEVNLRY--RKSHPLALNDITFEIKGGEKVGIIGRTGSGKSSLANLIFRLYPVTNGTIYI 1177
Query: 490 GNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCT 549
+IR L K RR + + Q+P LFSGT+ N+ L ++ I A+ + +
Sbjct: 1178 DGVDIRTVGLVKLRRGISAIAQDPSLFSGTVRFNL----DPSLEYSDSMIWEALEKCHLK 1233
Query: 550 KFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVA 609
+ + L+ V G S G++Q LARA L+ I+ILDEAT+++D+ +++++
Sbjct: 1234 TLVQSLDKKLEADVSHGGNNFSVGERQLFCLARALLMKSRIVILDEATASVDAGTDKLIQ 1293
Query: 610 QSLQQRSARGKTTISIAHRVSTIQHSSRVIVL 641
+ ++ A T I IAHR+ +++ R++ L
Sbjct: 1294 EVIKTVFA-DATVIIIAHRLDNVRNMDRIMHL 1324
Score = 83.6 bits (205), Expect = 1e-15
Identities = 57/205 (27%), Positives = 100/205 (47%), Gaps = 17/205 (8%)
Query: 452 TVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQ 511
+++ GEH+ ++G G GKS + + SG + +D L R V Q
Sbjct: 507 SIKRGEHIAVIGAVGCGKSAILKAI-------SGHMFTTDDA-----LSVDRSQTVYVPQ 554
Query: 512 EPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLS 571
+ +F+GT+ DNI + + +N E R +A+ T+ L G +T VG RG LS
Sbjct: 555 KAWIFNGTVQDNILFG---DKMNSE-RYYKAVNGCQLTEDLTTLSVGDRTEVGERGATLS 610
Query: 572 GGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVST 631
GGQK R+ALARA ++ + D+ ++LD + + + + Q+ + K + + + +
Sbjct: 611 GGQKARVALARAVFQTKNLYLFDDIFASLDKKVANKIHEEIIQKLLKKKALMMVTNNMEL 670
Query: 632 IQHSSRVIVLNRHGTVAETGSFDKL 656
+ H RV+ + G + G+ D L
Sbjct: 671 LHHFDRVLFV-EGGNIVADGNHDIL 694
>CE23649 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1400
Score = 127 bits (320), Expect = 4e-29
Identities = 127/512 (24%), Positives = 224/512 (42%), Gaps = 40/512 (7%)
Query: 149 TQFYTALGGV-FVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGD 207
T FY A+ V VV ++ + + + RL R +A + +F D G
Sbjct: 807 TGFYAAVYLVALVVLTISGLFKACVFVKVSLTAATRLHDRMFQAVIHGATSFFDSTPTGR 866
Query: 208 LISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMAL 267
+++R S D + L +Q + + + +L A PL V+ +
Sbjct: 867 ILNRFSKDMD----EIDVKLPFTAEVFLQNMITCLGFLVVITSVFPYFLLFAIPLFVVFV 922
Query: 268 VYGK----RIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFH 323
V+ IRNL R S L L TI + ++ +R+ + ++K H
Sbjct: 923 VFVSCFRAGIRNLKRSEHISRSPLYDHVSASLEGITTIHTF----QQSNRFLEVLKK--H 976
Query: 324 VGLKEALTSGAFFGVTGFVGNVA----LLALLLTGT----SMIKTGLMTVGDLSSFMMYA 375
+ SGA F + +A LL +++T +++ TG ++ D + +A
Sbjct: 977 LDCN----SGAIFMFQSAMRWLAVWLDLLVVVMTAIVALLTVMLTGTVSPADAGMAIAFA 1032
Query: 376 VXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLE-----NKSIHF 430
V EL + RV D P + + +E N I+F
Sbjct: 1033 VQMSGIFQFAVRTQTELEAKMTSVERVSYYADNIPEDGEWNTRQGLDIESSWPANGQINF 1092
Query: 431 NHVKFSYPTRPQHHI-FEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKL 489
+ V Y R H + D+ F ++ GE V I+G +G GKS++A+L+ R Y + +G I +
Sbjct: 1093 SEVNLRY--RKSHPLALNDITFEIKGGEKVGIIGRTGSGKSSLANLIFRLYPVTNGTIYI 1150
Query: 490 GNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCT 549
+IR L K RR + + Q+P LFSGT+ N+ L ++ I A+ + +
Sbjct: 1151 DGVDIRTVGLVKLRRGISAIAQDPSLFSGTVRFNL----DPSLEYSDSMIWEALEKCHLK 1206
Query: 550 KFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVA 609
+ + L+ V G S G++Q LARA L+ I+ILDEAT+++D+ +++++
Sbjct: 1207 TLVQSLDKKLEADVSHGGNNFSVGERQLFCLARALLMKSRIVILDEATASVDAGTDKLIQ 1266
Query: 610 QSLQQRSARGKTTISIAHRVSTIQHSSRVIVL 641
+ ++ A T I IAHR+ +++ R++ L
Sbjct: 1267 EVIKTVFA-DATVIIIAHRLDNVRNMDRIMHL 1297
Score = 70.5 bits (171), Expect = 8e-12
Identities = 48/152 (31%), Positives = 77/152 (50%), Gaps = 16/152 (10%)
Query: 452 TVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQ 511
+++ GEH+ ++G G GKS + + SG + +D L R V Q
Sbjct: 507 SIKRGEHIAVIGAVGCGKSAILKAI-------SGHMFTTDDA-----LSVDRSQTVYVPQ 554
Query: 512 EPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLS 571
+ +F+GT+ DNI + + +N E R +A+ T+ L G +T VG RG LS
Sbjct: 555 KAWIFNGTVQDNILFG---DKMNSE-RYYKAVNGCQLTEDLTTLSVGDRTEVGERGATLS 610
Query: 572 GGQKQRIALARAFLLDPSILILDEATSALDSQ 603
GGQK R+ALARA ++ + D+ ++LD +
Sbjct: 611 GGQKARVALARAVFQTKNLYLFDDIFASLDKK 642
>7298517 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1275
Score = 127 bits (320), Expect = 4e-29
Identities = 123/518 (23%), Positives = 224/518 (42%), Gaps = 29/518 (5%)
Query: 158 VFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAG 217
+ V+ + + R + R +L + F + N G +++R S D G
Sbjct: 752 ITVLSIMVTIKRSFLFFNLAMRASIQLHNSMFRGISRASMYFFNKNPAGSILNRFSKDMG 811
Query: 218 IVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMA-------LVYG 270
V + L VIQ F+ FG + + + ++ A G++ L
Sbjct: 812 ----QVDEMLPTIIMTVIQDFLLFGGNIIVIAIVNPLFLIPALAFGIVIYYLRSFYLKTS 867
Query: 271 KRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEAL 330
++ L ++ V S LS + A + E Y D ++ +
Sbjct: 868 LDVKRLEASTRSPVYSHFAASLNGLSTIRAFGAGSILEAEFDGYQDMHSSASYMFIS--- 924
Query: 331 TSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXX 390
TS AF ++ +L + + S + D+ + A+
Sbjct: 925 TSRAF---AYWMDIFCVLFIAMITLSFFIFPPSSAADVGLAITQAMGLTGTVQWTVRQSA 981
Query: 391 ELMKGAGAAARVFELNDRKPL--IHPTIGKDPVTL--ENKSIHFNHVKFSY-PTRPQHHI 445
EL + R+ E + +P + T K P E I F + Y P +
Sbjct: 982 ELENTMISVERMIEYEEIEPEGPLEATADKKPHESWPEQGKIEFVELSLRYEPYLKSESV 1041
Query: 446 FEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRL 505
+ L+F ++P E V IVG +G GKS++ + L R G +++ + + D L R
Sbjct: 1042 LKSLSFVIKPKEKVGIVGRTGAGKSSLINALFRL-SYNDGSVRIDDKDTNDMGLHDLRSK 1100
Query: 506 LGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGP 565
+ ++ QEP+LFSGT+ N+ P + +D+ R+ A+ + +A+ GL+T +
Sbjct: 1101 ISIIPQEPVLFSGTVRHNLD---PFDEYSDD-RLWCALEEVELKDVVASVATGLETKITE 1156
Query: 566 RGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISI 625
G+ S GQ+Q + LARA L D IL++DEAT+ +D Q++ ++ +++ + R T +++
Sbjct: 1157 GGSNFSVGQRQLVCLARAILRDNRILVMDEATANVDPQTDALIQATIRNK-FRECTVLTV 1215
Query: 626 AHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSS 663
AHR+ TI S RV+V++ G V E G+ +L+ D++
Sbjct: 1216 AHRLHTIMDSDRVLVMDA-GRVVEFGTPYELLTADDTN 1252
Score = 102 bits (255), Expect = 2e-21
Identities = 99/423 (23%), Positives = 171/423 (40%), Gaps = 54/423 (12%)
Query: 265 MALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGE----KKEIHRYADEVRK 320
+ + GK+I L + + ++ E ++ + I+ Y E K H E+
Sbjct: 211 LQMYLGKKISGLRLKTAIRSDKRMRIMTEIIAGIQVIKMYAWELPFEKMVAHARHKEINS 270
Query: 321 VFHVGLKEALT---------SGAFFGVTGFVGNVALLALLLTG-TSMIKTGLMTV--GDL 368
+ HV + L F + GFV L+ LT + + T V ++
Sbjct: 271 IRHVAYAKCLIWSFNRFLTPVSIFLSLVGFV----LMGRFLTAEVAFLITAYYNVVRTNM 326
Query: 369 SSFMMYAVXXXXXXXXXXXXXXELMKGA------------GAAARVFELNDRKPLIHPTI 416
+++ V +L+ GA + E + K L+ PT
Sbjct: 327 TAYFSVGVTQTAETLVSIKRVQKLLLSGEVVAKDENVVSNGAEEDLQEARE-KLLVTPTP 385
Query: 417 GKDPVTLENKS---IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVA 473
+ P + S + + +K + T + +N V G V IVG +G GKS++
Sbjct: 386 MRAPEKPPHNSEDCVSISELKAKWTTNSPDYTLSGVNLQVHAGALVAIVGHTGSGKSSLI 445
Query: 474 SLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELV 533
+L + SGEI++ + QEP LFSGT+ NI + P
Sbjct: 446 QAILGELRVESGEIEVTGS-------------MSYASQEPWLFSGTVRQNILFGQPM--- 489
Query: 534 NDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILIL 593
D R + + + P +T +G RG LSGGQK RI+LAR+ D SI +L
Sbjct: 490 -DRRRYDLVVRKCALERDFELLPLKDKTILGDRGASLSGGQKARISLARSVYRDASIYLL 548
Query: 594 DEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSF 653
D+ SA+DS + + + R K I + H++ +Q + +++++ G V G++
Sbjct: 549 DDPLSAVDSSVARRLFEECLRGHLRDKIVILVTHQLQFLQQADQIVIMEM-GKVKAVGTY 607
Query: 654 DKL 656
+ L
Sbjct: 608 ESL 610
>YLL015w [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1559
Score = 127 bits (319), Expect = 6e-29
Identities = 126/534 (23%), Positives = 227/534 (41%), Gaps = 38/534 (7%)
Query: 163 ALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKS 222
A N+ I++L R +L K+ + TF + VG +I+R SSD V +
Sbjct: 1033 AFNNLRSIMMLLYCSIRGSKKLHESMAKSVIRSPMTFFETTPVGRIINRFSSDMDAVDSN 1092
Query: 223 VTQNLSDGTRAVIQGFV-----GFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLS 277
+ S ++++ V G+ M F+ + + V++ + + L R L
Sbjct: 1093 LQYIFSFFFKSILTYLVTVILVGYNMPWFLVFNMFLVVIYIYYQTFYIVLS-----RELK 1147
Query: 278 RQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFG 337
R + S + + E L+ I AY ++ I+ ++++ T+
Sbjct: 1148 RLISISYSPIMSLMSESLNGYSIIDAYDHFERFIYLNYEKIQYNVDFVFNFRSTNRWLSV 1207
Query: 338 VTGFVGNVALLALLLTGTSMIKTGL-MTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGA 396
+G +LA + + + T ++ G + M Y++ +
Sbjct: 1208 RLQTIGATIVLATAILALATMNTKRQLSSGMVGLLMSYSLEVTGSLTWIVRTTVTIETNI 1267
Query: 397 GAAARVFELNDRKP---LIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTV 453
+ R+ E + P I+P D I F + Y + ++N +
Sbjct: 1268 VSVERIVEYCELPPEAQSINPEKRPDENWPSKGGIEFKNYSTKYRENLDP-VLNNINVKI 1326
Query: 454 RPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEP 513
P E V IVG +G GKST++ L R + G+I + +I D L R L ++ Q+
Sbjct: 1327 EPCEKVGIVGRTGAGKSTLSLALFRILEPTEGKIIIDGIDISDIGLFDLRSHLAIIPQDA 1386
Query: 514 MLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFL-----------------ANFP 556
F GT+ N+ P + E + RA+ QA+ L N
Sbjct: 1387 QAFEGTVKTNLD---PFNRYS-EDELKRAVEQAHLKPHLEKMLHSKPRGDDSNEEDGNVN 1442
Query: 557 DGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRS 616
D L + G+ LS GQ+Q + LARA L IL+LDEAT+++D ++++++ ++ +R
Sbjct: 1443 DILDVKINENGSNLSVGQRQLLCLARALLNRSKILVLDEATASVDMETDKIIQDTI-RRE 1501
Query: 617 ARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
+ +T ++IAHR+ T+ S ++IVL++ G+V E S KL++ S L K
Sbjct: 1502 FKDRTILTIAHRIDTVLDSDKIIVLDQ-GSVREFDSPSKLLSDKTSIFYSLCEK 1554
Score = 81.3 bits (199), Expect = 5e-15
Identities = 67/226 (29%), Positives = 109/226 (47%), Gaps = 15/226 (6%)
Query: 450 NFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVV 509
+F + G+ VC+VG G GKST +L SG D+I L +
Sbjct: 659 HFEAKRGDLVCVVGRVGAGKSTFLKAILGQLPCMSGS----RDSIPP-KLIIRSSSVAYC 713
Query: 510 QQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQ 569
QE + + ++ +NI + D+ I L PDG +T VG +G
Sbjct: 714 SQESWIMNASVRENILFGHKF----DQDYYDLTIKACQLLPDLKILPDGDETLVGEKGIS 769
Query: 570 LSGGQKQRIALARAFLLDPSILILDEATSALDSQ-SEEVVAQSLQQRSA--RGKTTISIA 626
LSGGQK R++LARA I +LD+ SA+D++ S+ ++ L ++A + KT I
Sbjct: 770 LSGGQKARLSLARAVYSRADIYLLDDILSAVDAEVSKNIIEYVLIGKTALLKNKTIILTT 829
Query: 627 HRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPD--SSLNKLLSK 670
+ VS ++HS + L +G + E G+++ ++ + S L KLL +
Sbjct: 830 NTVSILKHSQMIYAL-ENGEIVEQGNYEDVMNRKNNTSKLKKLLEE 874
>Hs9955960 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1482
Score = 127 bits (318), Expect = 8e-29
Identities = 134/534 (25%), Positives = 234/534 (43%), Gaps = 65/534 (12%)
Query: 152 YTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISR 211
Y ALG + +A G + + + G L + + L +F + G+L++R
Sbjct: 970 YGALG---ISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNR 1026
Query: 212 LSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLA--------PPLG 263
S + V + + VI+ F+G S + C+++LLA PPLG
Sbjct: 1027 FSKELDTVDSMIPE--------VIKMFMG----SLFNVIGACIVILLATPIAAIIIPPLG 1074
Query: 264 VMALV----YGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRY---AD 316
++ Y R L R S + E L I+A+ +++ IH+ D
Sbjct: 1075 LIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVD 1134
Query: 317 EVRKVFHVGLKEALTSGAFFGVT-GFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYA 375
E +K ++ ++ + + V VGN +L L ++I ++ G + + Y+
Sbjct: 1135 ENQKAYY----PSIVANRWLAVRLECVGNCIVLFAALF--AVISRHSLSAGLVGLSVSYS 1188
Query: 376 VXXXXXXXXXXXXXXELMKGAGAAARVFELNDRK------------PLIHPTIGKDPVTL 423
+ E+ A R+ E ++ + P P +G+
Sbjct: 1189 LQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGR----- 1243
Query: 424 ENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG 483
+ F + Y + +N T+ GE V IVG +G GKS++ L R +
Sbjct: 1244 ----VEFRNYCLRY-REDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESA 1298
Query: 484 SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAI 543
GEI + NI L R + ++ Q+P+LFSG++ N+ P +DE + ++
Sbjct: 1299 EGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLD---PFSQYSDE-EVWTSL 1354
Query: 544 GQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQ 603
A+ F++ PD L G LS GQ+Q + LARA L IL+LDEAT+A+D +
Sbjct: 1355 ELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLE 1414
Query: 604 SEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+++++ QS + T ++IAHR++TI +RVIVL++ G + E G+ L+
Sbjct: 1415 TDDLI-QSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDK-GEIQEYGAPSDLL 1466
Score = 78.6 bits (192), Expect = 3e-14
Identities = 63/244 (25%), Positives = 112/244 (45%), Gaps = 28/244 (11%)
Query: 417 GKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL 476
G + +T+ N + F + PT + F++ G V +VG G GKS++ S L
Sbjct: 591 GTNSITVRNAT--FTWARSDPPT------LNGITFSIPEGALVAVVGQVGCGKSSLLSAL 642
Query: 477 LRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDE 536
L D G + + + V Q+ + + ++ +NI + E E
Sbjct: 643 LAEMDKVEGHVAIKGS-------------VAYVPQQAWIQNDSLRENILFGCQLE----E 685
Query: 537 TRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEA 596
I L P G +T +G +G LSGGQKQR++LARA + I + D+
Sbjct: 686 PYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDP 745
Query: 597 TSALDSQSEEVVAQSL--QQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFD 654
SA+D+ + + +++ + + KT I + H +S + +IV++ G ++E GS+
Sbjct: 746 LSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMS-GGKISEMGSYQ 804
Query: 655 KLIA 658
+L+A
Sbjct: 805 ELLA 808
>Hs9955958 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1489
Score = 127 bits (318), Expect = 8e-29
Identities = 134/534 (25%), Positives = 234/534 (43%), Gaps = 65/534 (12%)
Query: 152 YTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISR 211
Y ALG + +A G + + + G L + + L +F + G+L++R
Sbjct: 977 YGALG---ISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNR 1033
Query: 212 LSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLA--------PPLG 263
S + V + + VI+ F+G S + C+++LLA PPLG
Sbjct: 1034 FSKELDTVDSMIPE--------VIKMFMG----SLFNVIGACIVILLATPIAAIIIPPLG 1081
Query: 264 VMALV----YGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRY---AD 316
++ Y R L R S + E L I+A+ +++ IH+ D
Sbjct: 1082 LIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVD 1141
Query: 317 EVRKVFHVGLKEALTSGAFFGVT-GFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYA 375
E +K ++ ++ + + V VGN +L L ++I ++ G + + Y+
Sbjct: 1142 ENQKAYY----PSIVANRWLAVRLECVGNCIVLFAALF--AVISRHSLSAGLVGLSVSYS 1195
Query: 376 VXXXXXXXXXXXXXXELMKGAGAAARVFELNDRK------------PLIHPTIGKDPVTL 423
+ E+ A R+ E ++ + P P +G+
Sbjct: 1196 LQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGR----- 1250
Query: 424 ENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG 483
+ F + Y + +N T+ GE V IVG +G GKS++ L R +
Sbjct: 1251 ----VEFRNYCLRY-REDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESA 1305
Query: 484 SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAI 543
GEI + NI L R + ++ Q+P+LFSG++ N+ P +DE + ++
Sbjct: 1306 EGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLD---PFSQYSDE-EVWTSL 1361
Query: 544 GQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQ 603
A+ F++ PD L G LS GQ+Q + LARA L IL+LDEAT+A+D +
Sbjct: 1362 ELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLE 1421
Query: 604 SEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+++++ QS + T ++IAHR++TI +RVIVL++ G + E G+ L+
Sbjct: 1422 TDDLI-QSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDK-GEIQEYGAPSDLL 1473
Score = 78.6 bits (192), Expect = 3e-14
Identities = 63/244 (25%), Positives = 112/244 (45%), Gaps = 28/244 (11%)
Query: 417 GKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL 476
G + +T+ N + F + PT + F++ G V +VG G GKS++ S L
Sbjct: 598 GTNSITVRNAT--FTWARSDPPT------LNGITFSIPEGALVAVVGQVGCGKSSLLSAL 649
Query: 477 LRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDE 536
L D G + + + V Q+ + + ++ +NI + E E
Sbjct: 650 LAEMDKVEGHVAIKGS-------------VAYVPQQAWIQNDSLRENILFGCQLE----E 692
Query: 537 TRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEA 596
I L P G +T +G +G LSGGQKQR++LARA + I + D+
Sbjct: 693 PYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDP 752
Query: 597 TSALDSQSEEVVAQSL--QQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFD 654
SA+D+ + + +++ + + KT I + H +S + +IV++ G ++E GS+
Sbjct: 753 LSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMS-GGKISEMGSYQ 811
Query: 655 KLIA 658
+L+A
Sbjct: 812 ELLA 815
>Hs9955954 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1416
Score = 127 bits (318), Expect = 8e-29
Identities = 134/534 (25%), Positives = 234/534 (43%), Gaps = 65/534 (12%)
Query: 152 YTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISR 211
Y ALG + +A G + + + G L + + L +F + G+L++R
Sbjct: 904 YGALG---ISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNR 960
Query: 212 LSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLA--------PPLG 263
S + V + + VI+ F+G S + C+++LLA PPLG
Sbjct: 961 FSKELDTVDSMIPE--------VIKMFMG----SLFNVIGACIVILLATPIAAIIIPPLG 1008
Query: 264 VMALV----YGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRY---AD 316
++ Y R L R S + E L I+A+ +++ IH+ D
Sbjct: 1009 LIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVD 1068
Query: 317 EVRKVFHVGLKEALTSGAFFGVT-GFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYA 375
E +K ++ ++ + + V VGN +L L ++I ++ G + + Y+
Sbjct: 1069 ENQKAYY----PSIVANRWLAVRLECVGNCIVLFAALF--AVISRHSLSAGLVGLSVSYS 1122
Query: 376 VXXXXXXXXXXXXXXELMKGAGAAARVFELNDRK------------PLIHPTIGKDPVTL 423
+ E+ A R+ E ++ + P P +G+
Sbjct: 1123 LQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGR----- 1177
Query: 424 ENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG 483
+ F + Y + +N T+ GE V IVG +G GKS++ L R +
Sbjct: 1178 ----VEFRNYCLRY-REDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESA 1232
Query: 484 SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAI 543
GEI + NI L R + ++ Q+P+LFSG++ N+ P +DE + ++
Sbjct: 1233 EGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLD---PFSQYSDE-EVWTSL 1288
Query: 544 GQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQ 603
A+ F++ PD L G LS GQ+Q + LARA L IL+LDEAT+A+D +
Sbjct: 1289 ELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLE 1348
Query: 604 SEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+++++ QS + T ++IAHR++TI +RVIVL++ G + E G+ L+
Sbjct: 1349 TDDLI-QSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDK-GEIQEYGAPSDLL 1400
>Hs9955952 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1475
Score = 127 bits (318), Expect = 8e-29
Identities = 134/534 (25%), Positives = 234/534 (43%), Gaps = 65/534 (12%)
Query: 152 YTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISR 211
Y ALG + +A G + + + G L + + L +F + G+L++R
Sbjct: 963 YGALG---ISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNR 1019
Query: 212 LSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLA--------PPLG 263
S + V + + VI+ F+G S + C+++LLA PPLG
Sbjct: 1020 FSKELDTVDSMIPE--------VIKMFMG----SLFNVIGACIVILLATPIAAIIIPPLG 1067
Query: 264 VMALV----YGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRY---AD 316
++ Y R L R S + E L I+A+ +++ IH+ D
Sbjct: 1068 LIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVD 1127
Query: 317 EVRKVFHVGLKEALTSGAFFGVT-GFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYA 375
E +K ++ ++ + + V VGN +L L ++I ++ G + + Y+
Sbjct: 1128 ENQKAYY----PSIVANRWLAVRLECVGNCIVLFAALF--AVISRHSLSAGLVGLSVSYS 1181
Query: 376 VXXXXXXXXXXXXXXELMKGAGAAARVFELNDRK------------PLIHPTIGKDPVTL 423
+ E+ A R+ E ++ + P P +G+
Sbjct: 1182 LQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGR----- 1236
Query: 424 ENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG 483
+ F + Y + +N T+ GE V IVG +G GKS++ L R +
Sbjct: 1237 ----VEFRNYCLRY-REDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESA 1291
Query: 484 SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAI 543
GEI + NI L R + ++ Q+P+LFSG++ N+ P +DE + ++
Sbjct: 1292 EGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLD---PFSQYSDE-EVWTSL 1347
Query: 544 GQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQ 603
A+ F++ PD L G LS GQ+Q + LARA L IL+LDEAT+A+D +
Sbjct: 1348 ELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLE 1407
Query: 604 SEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+++++ QS + T ++IAHR++TI +RVIVL++ G + E G+ L+
Sbjct: 1408 TDDLI-QSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDK-GEIQEYGAPSDLL 1459
>Hs9955950 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1472
Score = 127 bits (318), Expect = 8e-29
Identities = 134/534 (25%), Positives = 234/534 (43%), Gaps = 65/534 (12%)
Query: 152 YTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISR 211
Y ALG + +A G + + + G L + + L +F + G+L++R
Sbjct: 960 YGALG---ISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNR 1016
Query: 212 LSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLA--------PPLG 263
S + V + + VI+ F+G S + C+++LLA PPLG
Sbjct: 1017 FSKELDTVDSMIPE--------VIKMFMG----SLFNVIGACIVILLATPIAAIIIPPLG 1064
Query: 264 VMALV----YGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRY---AD 316
++ Y R L R S + E L I+A+ +++ IH+ D
Sbjct: 1065 LIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVD 1124
Query: 317 EVRKVFHVGLKEALTSGAFFGVT-GFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYA 375
E +K ++ ++ + + V VGN +L L ++I ++ G + + Y+
Sbjct: 1125 ENQKAYY----PSIVANRWLAVRLECVGNCIVLFAALF--AVISRHSLSAGLVGLSVSYS 1178
Query: 376 VXXXXXXXXXXXXXXELMKGAGAAARVFELNDRK------------PLIHPTIGKDPVTL 423
+ E+ A R+ E ++ + P P +G+
Sbjct: 1179 LQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGR----- 1233
Query: 424 ENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG 483
+ F + Y + +N T+ GE V IVG +G GKS++ L R +
Sbjct: 1234 ----VEFRNYCLRY-REDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESA 1288
Query: 484 SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAI 543
GEI + NI L R + ++ Q+P+LFSG++ N+ P +DE + ++
Sbjct: 1289 EGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLD---PFSQYSDE-EVWTSL 1344
Query: 544 GQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQ 603
A+ F++ PD L G LS GQ+Q + LARA L IL+LDEAT+A+D +
Sbjct: 1345 ELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLE 1404
Query: 604 SEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+++++ QS + T ++IAHR++TI +RVIVL++ G + E G+ L+
Sbjct: 1405 TDDLI-QSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDK-GEIQEYGAPSDLL 1456
Score = 63.9 bits (154), Expect = 8e-10
Identities = 44/146 (30%), Positives = 78/146 (53%), Gaps = 16/146 (10%)
Query: 521 LDNITYAVPQELVNDETRISRAIGQANCTK------FLANFPDGLQTTVGPRGTQLSGGQ 574
L+ IT+++P E + +GQ C K LA D ++ V +G LSGGQ
Sbjct: 661 LNGITFSIP------EGALVAVVGQVGCGKSSLLSALLAEM-DKVEGHVAIKGVNLSGGQ 713
Query: 575 KQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSL--QQRSARGKTTISIAHRVSTI 632
KQR++LARA + I + D+ SA+D+ + + +++ + + KT I + H +S +
Sbjct: 714 KQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYL 773
Query: 633 QHSSRVIVLNRHGTVAETGSFDKLIA 658
+IV++ G ++E GS+ +L+A
Sbjct: 774 PQVDVIIVMS-GGKISEMGSYQELLA 798
>Hs4826838 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1531
Score = 127 bits (318), Expect = 8e-29
Identities = 134/534 (25%), Positives = 234/534 (43%), Gaps = 65/534 (12%)
Query: 152 YTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISR 211
Y ALG + +A G + + + G L + + L +F + G+L++R
Sbjct: 1019 YGALG---ISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNR 1075
Query: 212 LSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLA--------PPLG 263
S + V + + VI+ F+G S + C+++LLA PPLG
Sbjct: 1076 FSKELDTVDSMIPE--------VIKMFMG----SLFNVIGACIVILLATPIAAIIIPPLG 1123
Query: 264 VMALV----YGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRY---AD 316
++ Y R L R S + E L I+A+ +++ IH+ D
Sbjct: 1124 LIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVD 1183
Query: 317 EVRKVFHVGLKEALTSGAFFGVT-GFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYA 375
E +K ++ ++ + + V VGN +L L ++I ++ G + + Y+
Sbjct: 1184 ENQKAYY----PSIVANRWLAVRLECVGNCIVLFAALF--AVISRHSLSAGLVGLSVSYS 1237
Query: 376 VXXXXXXXXXXXXXXELMKGAGAAARVFELNDRK------------PLIHPTIGKDPVTL 423
+ E+ A R+ E ++ + P P +G+
Sbjct: 1238 LQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGR----- 1292
Query: 424 ENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG 483
+ F + Y + +N T+ GE V IVG +G GKS++ L R +
Sbjct: 1293 ----VEFRNYCLRY-REDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESA 1347
Query: 484 SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAI 543
GEI + NI L R + ++ Q+P+LFSG++ N+ P +DE + ++
Sbjct: 1348 EGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLD---PFSQYSDE-EVWTSL 1403
Query: 544 GQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQ 603
A+ F++ PD L G LS GQ+Q + LARA L IL+LDEAT+A+D +
Sbjct: 1404 ELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLE 1463
Query: 604 SEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+++++ QS + T ++IAHR++TI +RVIVL++ G + E G+ L+
Sbjct: 1464 TDDLI-QSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDK-GEIQEYGAPSDLL 1515
Score = 78.6 bits (192), Expect = 3e-14
Identities = 63/244 (25%), Positives = 112/244 (45%), Gaps = 28/244 (11%)
Query: 417 GKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL 476
G + +T+ N + F + PT + F++ G V +VG G GKS++ S L
Sbjct: 640 GTNSITVRNAT--FTWARSDPPT------LNGITFSIPEGALVAVVGQVGCGKSSLLSAL 691
Query: 477 LRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDE 536
L D G + + + V Q+ + + ++ +NI + E E
Sbjct: 692 LAEMDKVEGHVAIKGS-------------VAYVPQQAWIQNDSLRENILFGCQLE----E 734
Query: 537 TRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEA 596
I L P G +T +G +G LSGGQKQR++LARA + I + D+
Sbjct: 735 PYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDP 794
Query: 597 TSALDSQSEEVVAQSL--QQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFD 654
SA+D+ + + +++ + + KT I + H +S + +IV++ G ++E GS+
Sbjct: 795 LSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMS-GGKISEMGSYQ 853
Query: 655 KLIA 658
+L+A
Sbjct: 854 ELLA 857
>Hs4557481 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1545
Score = 126 bits (316), Expect = 1e-28
Identities = 128/489 (26%), Positives = 223/489 (45%), Gaps = 31/489 (6%)
Query: 184 LRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGM 243
L + + L F D G +++R + D V ++ Q+L R+ I F+G
Sbjct: 1056 LHKQLLNNILRAPMRFFDTTPTGRIVNRFAGDISTVDDTLPQSL----RSWITCFLGIIS 1111
Query: 244 MSFISWKLTCVMMLLAPPLGVM----ALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATK 299
+ T V ++ PLG++ + Y R L R + + E +S
Sbjct: 1112 TLVMICMATPVFTIIVIPLGIIYVSVQMFYVSTSRQLRRLDSVTRSPIYSHFSETVSGLP 1171
Query: 300 TIQAYCGEKKEIHRYADEVR-KVFHVGLKEALTSGAFFGVT-GFVGNVALLALLLTGTSM 357
I+A+ +++ + +EVR + +TS + + VGN L + + M
Sbjct: 1172 VIRAFEHQQRFLKH--NEVRIDTNQKCVFSWITSNRWLAIRLELVGN---LTVFFSALMM 1226
Query: 358 IKTGLMTVGDLSSFMMY-AVXXXXXXXXXXXXXXELMKGAGAAARVFE---LNDRKPLIH 413
+ GD F++ A+ E+ A R+ E + + P +
Sbjct: 1227 VIYRDTLSGDTVGFVLSNALNITQTLNWLVRMTSEIETNIVAVERITEYTKVENEAPWV- 1285
Query: 414 PTIGKDPVTLENKS-IHFNHVKFSYPTRPQHH-IFEDLNFTVRPGEHVCIVGPSGGGKST 471
T + P +K I FN+ + Y RP+ + + + E + +VG +G GKS+
Sbjct: 1286 -TDKRPPPDWPSKGKIQFNNYQVRY--RPELDLVLRGITCDIGSMEKIGVVGRTGAGKSS 1342
Query: 472 VASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQE 531
+ + L R + G+I + +I L R L ++ Q+P+LFSG++ N+ P
Sbjct: 1343 LTNCLFRILEAAGGQIIIDGVDIASIGLHDLREKLTIIPQDPILFSGSLRMNLD---PFN 1399
Query: 532 LVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSIL 591
+DE I +A+ A+ F+A+ GL V G LS GQ+Q + L RA L IL
Sbjct: 1400 NYSDE-EIWKALELAHLKSFVASLQLGLSHEVTEAGGNLSIGQRQLLCLGRALLRKSKIL 1458
Query: 592 ILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETG 651
+LDEAT+A+D +++ ++ ++Q A T I+IAHR+ TI S +V+VL+ +G + E G
Sbjct: 1459 VLDEATAAVDLETDNLIQTTIQNEFAH-CTVITIAHRLHTIMDSDKVMVLD-NGKIIECG 1516
Query: 652 SFDKLIAIP 660
S ++L+ IP
Sbjct: 1517 SPEELLQIP 1525
Score = 90.9 bits (224), Expect = 6e-18
Identities = 64/236 (27%), Positives = 113/236 (47%), Gaps = 21/236 (8%)
Query: 425 NKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGS 484
+K++ F+ F++ + + D+N + G+ V ++GP G GKS++ S +L +
Sbjct: 634 DKAMQFSEASFTWEHDSEATV-RDVNLDIMAGQLVAVIGPVGSGKSSLISAMLGEMENVH 692
Query: 485 GEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIG 544
G I + + V Q+ + +GTI DNI + +E R + +
Sbjct: 693 GHITI-------------KGTTAYVPQQSWIQNGTIKDNILFGTEF----NEKRYQQVLE 735
Query: 545 QANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQS 604
L P G +G +G LSGGQKQRI+LARA + I +LD+ SA+D+
Sbjct: 736 ACALLPDLEMLPGGDLAEIGEKGINLSGGQKQRISLARATYQNLDIYLLDDPLSAVDAHV 795
Query: 605 EEVVAQSLQQRSA--RGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
+ + + + +GKT + + H + + ++VL +GT+ E GS+ L+A
Sbjct: 796 GKHIFNKVLGPNGLLKGKTRLLVTHSMHFLPQVDEIVVLG-NGTIVEKGSYSALLA 850
>YLL048c [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1661
Score = 125 bits (313), Expect = 3e-28
Identities = 112/530 (21%), Positives = 233/530 (43%), Gaps = 54/530 (10%)
Query: 148 STQFYTALGGVFVVG---ALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNR 204
ST +Y L ++G AL G+ ++ V G ++ + L F D
Sbjct: 1100 STMYYLVL--YLIIGFAQALLGAGKTILNFVAGINASRKIFNMILNKVLHSKIRFFDATP 1157
Query: 205 VGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGV 264
G +++R S D + + +T + ++I+ +++FI+ + V ++++
Sbjct: 1158 TGRIMNRFSKDIEAIDQELTPYIQGAFYSLIECLSTVILITFITPQFLSVAIVVSILYYF 1217
Query: 265 MALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGE----KKEIHRYADEVRK 320
+ Y R L R S + + E L TI+A+ E ++ +H+ + +
Sbjct: 1218 VGYFYMAGSRELKRFESISRSPIYQHFSETLVGVTTIRAFGDEGRFMQENLHKIDENNKP 1277
Query: 321 VFHVGLKEALTSGAFFGVTGFVGNVALLA---LLLTGTSMIKTGLMTVGDLSSFMMYAVX 377
F++ + + +G++ + +L + + +G+ + + YA+
Sbjct: 1278 FFYLWVANRWLAFRI----DMIGSLVIFGAGLFILFNINNLDSGMAGIS-----LTYAIS 1328
Query: 378 XXXXXXXXXXXXXELMKGAGAAARVFELND--RKPLIHPTIGKDPVTLENKSIHFNHVKF 435
E+ + RV E + ++P P ++ I N +
Sbjct: 1329 FTEGALWLVRLYSEVEMNMNSVERVKEYMEIEQEPYNEHKEIPPPQWPQDGKIEVNDLSL 1388
Query: 436 SY-PTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNI 494
Y P P+ + ++++F+V + IVG +G GKST+ + L R+ + +G IK+ N +I
Sbjct: 1389 RYAPNLPR--VIKNVSFSVDAQSKIGIVGRTGAGKSTIITALFRFLEPETGHIKIDNIDI 1446
Query: 495 RDFNLRKYRRLLGVVQQEPMLFSGTILDNI----------------------TYAVPQEL 532
+L++ RR + ++ Q+P LFSGTI N+ + Q
Sbjct: 1447 SGVDLQRLRRSITIIPQDPTLFSGTIKTNLDPYDEFSDRQIFEALKRVNLISEEQLQQGA 1506
Query: 533 VNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILI 592
+ + + + N KFL L + + G+ LS GQ+Q + LAR+ L P I++
Sbjct: 1507 TRETSNEASSTNSENVNKFL-----DLSSEISEGGSNLSQGQRQLMCLARSLLRSPKIIL 1561
Query: 593 LDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLN 642
LDEAT+++D S+ + +++ ++ +G T ++IAHR+ ++ +++V++
Sbjct: 1562 LDEATASIDYSSDAKIQETI-RKEFQGSTILTIAHRLRSVIDYDKILVMD 1610
Score = 72.8 bits (177), Expect = 2e-12
Identities = 58/233 (24%), Positives = 102/233 (42%), Gaps = 22/233 (9%)
Query: 430 FNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKL 489
F + S+ Q +DLN + G+ ++GP+G GK+++ LL GE+ L
Sbjct: 696 FENSTISWDKDNQDFKLKDLNIEFKTGKLNVVIGPTGSGKTSLLMALL-------GEMYL 748
Query: 490 GNDNIRDFNLRKYRRLL----------GVVQQEPMLFSGTILDNITYAVPQELVNDETRI 539
N + L + L+ Q L + T+ +NI + P +E R
Sbjct: 749 LNGKVVVPALEPRQELIVDANGTTNSIAYCSQAAWLLNDTVKNNILFNSPF----NEARY 804
Query: 540 SRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSA 599
+ + G T +G +G LSGGQKQR++LARA + ++LD+ SA
Sbjct: 805 KAVVEACGLKRDFEILKAGDLTEIGEKGITLSGGQKQRVSLARALYSNARHVLLDDCLSA 864
Query: 600 LDSQSEE-VVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETG 651
+DS + + + +T I ++H ++ ++ ++VL G V + G
Sbjct: 865 VDSHTASWIYDNCITGPLMEDRTCILVSHNIALTLRNAELVVLLEDGRVKDQG 917
>7299468 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1307
Score = 125 bits (313), Expect = 3e-28
Identities = 121/475 (25%), Positives = 217/475 (45%), Gaps = 23/475 (4%)
Query: 199 FLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLL 258
F + N G +++R S D G + + + + D V+Q F+ + + ++L
Sbjct: 814 FFNTNPSGRILNRFSKDLGQLDEVLPSVMLD----VVQLFLTLLGIIVVICITNPYYLIL 869
Query: 259 APPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSAT----KTIQAYCGEKKEIHRY 314
L ++ + SR ++ LSAT TI+A G +KE+
Sbjct: 870 TLALAIIFYYIREFYLKTSRDVKRLEAVARSPIYSHLSATITGLPTIRAL-GAQKELIAE 928
Query: 315 ADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMY 374
D ++ + G L + FG ++ L +++ + + G++ +
Sbjct: 929 FDNLQDLHSSGYYTFLATNRAFGY--YLDCFCTLYIVIIILNYFINPPQSPGEVGLAITQ 986
Query: 375 AVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPL--IHPTIGKDPVTL--ENKSIHF 430
A+ EL A RV E ++ +P GK P E I
Sbjct: 987 AMGMTGMVQWAMRQSAELENTMTAVERVVEYDEIEPEGEFDSREGKKPSPSWPEKGEIIA 1046
Query: 431 NHVKFSYPTRPQ-HHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKL 489
+ Y PQ ++ + LNF +RP E V IVG +G GKS++ + L R G I +
Sbjct: 1047 EDLCLRYFPDPQAKYVLKALNFRIRPCEKVGIVGRTGAGKSSLINALFRL-SYNEGIITI 1105
Query: 490 GNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCT 549
+ D L R + ++ QEP+LFSG++ N+ P E ND ++ A+ +
Sbjct: 1106 DERDTADMGLFDLRSKISIIPQEPVLFSGSMRYNLD---PFEEYND-AKLWDALEEVKLK 1161
Query: 550 KFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVA 609
++ P+GLQ+ + G+ S GQ+Q + LARA L + +L++DEAT+ +D Q++ ++
Sbjct: 1162 PLISELPNGLQSKISEGGSNFSVGQRQLVCLARAILRENRVLVMDEATANVDPQTDALIQ 1221
Query: 610 QSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSL 664
+++ + R T ++IAHR++TI S RV+V++ G + E GS +L+ +S +
Sbjct: 1222 ATIRSK-FRDCTVLTIAHRLNTIMDSDRVLVMDA-GHLVEFGSPYELLTSSESKI 1274
Score = 86.7 bits (213), Expect = 1e-16
Identities = 56/229 (24%), Positives = 105/229 (45%), Gaps = 18/229 (7%)
Query: 428 IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEI 487
I F+ + + + ED+N + + V ++GP G GKS++ +L SG +
Sbjct: 413 IEFSQFQARWESHSLEPTLEDINLQLGRRKLVAVIGPVGAGKSSLIQAILGELPGESGTL 472
Query: 488 KLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQAN 547
++ QEP LF+GT+ NI + + D+ R + +
Sbjct: 473 RINGS-------------YSYAAQEPWLFTGTVRQNILFGLDW----DKHRYRTVVKKCA 515
Query: 548 CTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEV 607
+ P G +T VG RG LSGGQK RI+LARA I +LD+ SA+D+
Sbjct: 516 LERDFELLPFGDKTIVGERGASLSGGQKARISLARAVYRRADIYLLDDPLSAVDTHVGRH 575
Query: 608 VAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
+ + R + I + H++ ++ + ++++++ G ++ G++ +
Sbjct: 576 LFDQCMRGYLRSELVILVTHQLQFLEQADLIVIMDK-GRISAMGTYSSM 623
>YGR281w [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1477
Score = 124 bits (312), Expect = 4e-28
Identities = 140/546 (25%), Positives = 231/546 (41%), Gaps = 39/546 (7%)
Query: 151 FYTALGGVFVVGALANV-GRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLI 209
FY L FV A + G+ IL G L R +K L +++D +G ++
Sbjct: 933 FYMGLYSFFVFAAFIFMNGQFTILCAMGIMASKWLNLRAVKRILHTPMSYIDTTPLGRIL 992
Query: 210 SRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMS--FISWKLTCVMMLLAPPLGVMAL 267
+R + D + +T++L T + VG +M ++ W + LL + ++A
Sbjct: 993 NRFTKDTDSLDNELTESLRLMT-SQFANIVGVCVMCIVYLPWFAIAIPFLLVIFV-LIAD 1050
Query: 268 VYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLK 327
Y R + R + E L TI+AY +++ + + + K+ G
Sbjct: 1051 HYQSSGREIKRLEAVQRSFVYNNLNEVLGGMDTIKAYRSQERFLAKSDFLINKMNEAGYL 1110
Query: 328 EALTS---GAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXX 384
+ G F + AL+ LL T +VG L ++++
Sbjct: 1111 VVVLQRWVGIFLDMVAIA--FALIITLLCVTRAFPISAASVGVLLTYVLQLPGLLNTILR 1168
Query: 385 XXXXXXELMKGAG-----AAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSY-P 438
M A A E + RKP + P + I F +V F+Y P
Sbjct: 1169 AMTQTENDMNSAERLVTYATELPLEASYRKPEMTPPESWPSMG----EIIFENVDFAYRP 1224
Query: 439 TRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFN 498
P + ++LN ++ GE + I G +G GKST+ S L R ++ +G+I + N +I
Sbjct: 1225 GLPI--VLKNLNLNIKSGEKIGICGRTGAGKSTIMSALYRLNELTAGKILIDNVDISQLG 1282
Query: 499 LRKYRRLLGVVQQEPMLFSGTI---LDNITYAVPQELVNDETRISRAIGQANCTKFLANF 555
L RR L ++ Q+P+LF GTI LD EL + R AI + + +
Sbjct: 1283 LFDLRRKLAIIPQDPVLFRGTIRKNLDPFNERTDDELWDALVR-GGAIAKDDLPEVKLQK 1341
Query: 556 PD-----------GLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQS 604
PD L V G+ S G++Q +AL RA + ILILDEATS++D ++
Sbjct: 1342 PDENGTHGKMHKFHLDQAVEEEGSNFSLGERQLLALTRALVRQSKILILDEATSSVDYET 1401
Query: 605 EEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSL 664
+ + + + T + IAHR+ TI + R++VL + G VAE + L + DS
Sbjct: 1402 DGKIQTRIVEEFG-DCTILCIAHRLKTIVNYDRILVLEK-GEVAEFDTPWTLFSQEDSIF 1459
Query: 665 NKLLSK 670
+ S+
Sbjct: 1460 RSMCSR 1465
Score = 92.0 bits (227), Expect = 3e-18
Identities = 66/222 (29%), Positives = 107/222 (47%), Gaps = 19/222 (8%)
Query: 446 FEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRL 505
F+DLNF ++ GE + I GP G GKS++ + + G++++ D + +
Sbjct: 604 FKDLNFDIKKGEFIMITGPIGTGKSSLLNAMAGSMRKTDGKVEVNGDLL----------M 653
Query: 506 LGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGP 565
G P + + ++ DNI + P ++ + + + L P G T +G
Sbjct: 654 CGY----PWIQNASVRDNIIFGSPF----NKEKYDEVVRVCSLKADLDILPAGDMTEIGE 705
Query: 566 RGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISI 625
RG LSGGQK RI LAR+ I + D+ SA+DS+ + + KT I
Sbjct: 706 RGITLSGGQKARINLARSVYKKKDIYLFDDVLSAVDSRVGKHIMDECLTGMLANKTRILA 765
Query: 626 AHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKL 667
H++S I+ +SRVIVL G V + G+ D+L A + +N L
Sbjct: 766 THQLSLIERASRVIVLGTDGQV-DIGTVDELKARNQTLINLL 806
>CE24285 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1153
Score = 123 bits (309), Expect = 8e-28
Identities = 81/241 (33%), Positives = 137/241 (56%), Gaps = 10/241 (4%)
Query: 433 VKFS-YPTRPQHH---IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIK 488
VKF Y TR + + D++ V GE + IVG +G GKS+ A L R + G I
Sbjct: 910 VKFDGYSTRYREGLDLVLHDISADVAAGEKIGIVGRTGAGKSSFALALFRMIEAAGGRIV 969
Query: 489 LGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANC 548
+ + + L R + ++ Q+P+LFSGT+ N+ P +D+ +I RA+ A+
Sbjct: 970 IDDVEVSQIGLHDLRSNITIIPQDPVLFSGTLRFNLD---PFFTYSDD-QIWRALELAHL 1025
Query: 549 TKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVV 608
F A PDGL + G LS GQ+Q +ALARA L +L+LDEAT+A+D ++ ++
Sbjct: 1026 KHFAAGLPDGLLYKISEAGENLSVGQRQLVALARALLRHTRVLVLDEATAAVDVATDALI 1085
Query: 609 AQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLL 668
+++++ + T +IAHR++TI R++VL++ G++ E + D L+A +S+ K++
Sbjct: 1086 QETIRE-EFKECTVFTIAHRLNTIMDYDRIMVLDK-GSILEFDTPDALMADKNSAFAKMV 1143
Query: 669 S 669
+
Sbjct: 1144 A 1144
Score = 64.7 bits (156), Expect = 5e-10
Identities = 45/156 (28%), Positives = 76/156 (47%), Gaps = 17/156 (10%)
Query: 447 EDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLL 506
+D++ T + +VG G GKS++ LL ++G ++G + +
Sbjct: 677 QDVDLTAPRNSLIAVVGKVGSGKSSLLQALLG--EMGKLRGRIGVNG-----------RV 723
Query: 507 GVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPR 566
V Q+P + + T+ DNIT+ P D R + + + P G QT +G +
Sbjct: 724 AYVPQQPWIQNMTLRDNITFGRPF----DRKRYDQVLYACALKADIKILPAGDQTEIGEK 779
Query: 567 GTQLSGGQKQRIALARAFLLDPSILILDEATSALDS 602
G LSGGQK R++LARA + + +LD+ SA+D+
Sbjct: 780 GINLSGGQKARVSLARAVYQNLDVYLLDDPLSAVDA 815
>Hs5032101 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1437
Score = 122 bits (307), Expect = 1e-27
Identities = 132/515 (25%), Positives = 224/515 (42%), Gaps = 34/515 (6%)
Query: 150 QFYTALGGVF--VVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGD 207
Q+Y ++ + V+ L + +V +K T R +RL + L F D G
Sbjct: 912 QYYASIYALSMAVMLILKAIRGVVFVKGT-LRASSRLHDELFRRILRSPMKFFDTTPTGR 970
Query: 208 LISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFI-SWKLTCVMMLLAPPLGVMA 266
+++R S D V + + VI F GM++ + W L V L+ V+
Sbjct: 971 ILNRFSKDMDEVDVRLPFQAEMFIQNVILVFFCVGMIAGVFPWFLVAVGPLVIL-FSVLH 1029
Query: 267 LVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGL 326
+V IR L R + + TI AY ++ +HRY + +
Sbjct: 1030 IVSRVLIRELKRLDNITQSPFLSHITSSIQGLATIHAYNKGQEFLHRYQELLDD------ 1083
Query: 327 KEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTV---GDLSSF-----MMYAVXX 378
FF T + +A+ L++ + TGLM V G + + YAV
Sbjct: 1084 ----NQAPFFLFTCAMRWLAVRLDLISIALITTTGLMIVLMHGQIPPAYAGLAISYAVQL 1139
Query: 379 XXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKD----PVTLENKSIHFNHVK 434
E + R+ L P K+ P + + F + +
Sbjct: 1140 TGLFQFTVRLASETEARFTSVERINHYIKTLSLEAPARIKNKAPSPDWPQEGEVTFENAE 1199
Query: 435 FSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNI 494
Y + + ++FT++P E + IVG +G GKS++ L R ++ G IK+ I
Sbjct: 1200 MRYRENLPL-VLKKVSFTIKPKEKIGIVGRTGSGKSSLGMALFRLVELSGGCIKIDGVRI 1258
Query: 495 RDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLAN 554
D L R L ++ QEP+LFSGT+ N+ P E +I A+ + + + +A
Sbjct: 1259 SDIGLADLRSKLSIIPQEPVLFSGTVRSNLD---PFNQYT-EDQIWDALERTHMKECIAQ 1314
Query: 555 FPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQ 614
P L++ V G S G++Q + +ARA L ILILDEAT+A+D++++ ++ +++++
Sbjct: 1315 LPLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIRE 1374
Query: 615 RSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAE 649
A T ++IAHR+ T+ S R++VL G V E
Sbjct: 1375 AFA-DCTMLTIAHRLHTVLGSDRIMVL-AQGQVVE 1407
Score = 92.8 bits (229), Expect = 2e-18
Identities = 68/238 (28%), Positives = 108/238 (44%), Gaps = 25/238 (10%)
Query: 420 PVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRY 479
P E K IH H++ R H I + ++ G+ V I G G GK+++ S +L
Sbjct: 559 PEEEEGKHIHLGHLRLQ---RTLHSI----DLEIQEGKLVGICGSVGSGKTSLISAILGQ 611
Query: 480 YDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRI 539
+ G I + V Q+ + + T+ DNI + DE R
Sbjct: 612 MTLLEGSIAISGT-------------FAYVAQQAWILNATLRDNILFGKEY----DEERY 654
Query: 540 SRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSA 599
+ + LA P T +G RG LSGGQ+QRI+LARA D SI ILD+ SA
Sbjct: 655 NSVLNSCCLRPDLAILPSSDLTEIGERGANLSGGQRQRISLARALYSDRSIYILDDPLSA 714
Query: 600 LDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
LD+ + S ++ + KT + + H++ + VI + + G + E G+ ++L+
Sbjct: 715 LDAHVGNHIFNSAIRKHLKSKTVLFVTHQLQYLVDCDEVIFM-KEGCITERGTHEELM 771
>SPAC30.04c [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1469
Score = 122 bits (305), Expect = 2e-27
Identities = 101/325 (31%), Positives = 155/325 (47%), Gaps = 25/325 (7%)
Query: 337 GVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGA 396
G++G VG +A L LL ++ G + + AV L
Sbjct: 1126 GISGLVGAIAGLIALLQKD-------LSPGVVGFSLNQAVIFSSSVLLFVRSCNSLQAEM 1178
Query: 397 GAAARVFELNDRKPLIHPTI-GKDPVTLENKS-IHFNHVKFSYPTRPQHHIFEDLNFTVR 454
+ RV E + PTI G+ P T + I FNHV SY I +D+N +
Sbjct: 1179 NSYERVLEYSKLPQEPAPTIAGQVPATWPKEGDIVFNHVSVSYSAAGPT-ILKDVNLHIN 1237
Query: 455 PGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPM 514
P E V +VG +G GKST+ LLR+ SGEI + + NL R+ + + Q+P+
Sbjct: 1238 PSEKVAVVGRTGSGKSTLGLTLLRFTHRISGEIYINGRETQSVNLNALRQRISFIPQDPI 1297
Query: 515 LFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDG-------LQTTVGPRG 567
LFSGT+ N+ P + + D ++ A+ + + + D L T V G
Sbjct: 1298 LFSGTVRSNLD---PFDELEDNF-LNEALKTSGASSMIMAHTDDQKPIHITLDTHVASEG 1353
Query: 568 TQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTT-ISIA 626
+ S GQKQ +ALARA + I+ILDE T+++D ++ + ++L R A G T + IA
Sbjct: 1354 SNFSQGQKQVLALARAIVRRSKIIILDECTASVDDAMDQKIQKTL--REAFGDATMLCIA 1411
Query: 627 HRVSTIQHSSRVIVLNRHGTVAETG 651
HR+ TI +V+VL++ G + E G
Sbjct: 1412 HRLKTIVDYDKVMVLDK-GVLVEYG 1435
Score = 90.9 bits (224), Expect = 6e-18
Identities = 77/234 (32%), Positives = 111/234 (46%), Gaps = 21/234 (8%)
Query: 419 DPV-TLENKS--IHFNHVKFSYPTRPQHHIF--EDLNFTVRPGEHVCIVGPSGGGKSTVA 473
DPV T+E+ S I F + ++ + P F DLN + ++GP+G GKS++
Sbjct: 599 DPVNTIEDTSQEIGFFNASLTWVSNPSPGDFCLRDLNIVFPRNKLSIVIGPTGSGKSSLI 658
Query: 474 SLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELV 533
S LL GE+ L N +NL + + + V Q P L + TI DNI + P
Sbjct: 659 SALL-------GELSL---NKGSYNLPRSKGV-SYVSQVPWLRNATIRDNILFDYPYI-- 705
Query: 534 NDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILIL 593
E R + I L +F T +G +G LSGGQKQRIALARA SI+++
Sbjct: 706 --EERYKKVIQACGLLTDLQSFVASDLTEIGEKGVTLSGGQKQRIALARAVYSPTSIVLM 763
Query: 594 DEATSALD-SQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGT 646
D+ SALD S + Q +T I + H V S+ IV ++G+
Sbjct: 764 DDVFSALDIHTSNWIYKHCFQSSLMENRTVILVTHNVHLFMDSAAFIVTVKNGS 817
>7297379 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1487
Score = 122 bits (305), Expect = 2e-27
Identities = 141/550 (25%), Positives = 236/550 (42%), Gaps = 75/550 (13%)
Query: 148 STQFYTAL-GGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVG 206
+T+FY ++ + V +L + R + G + + + +K + F D VG
Sbjct: 958 TTKFYLSIFTAIAVSNSLVTLARAFLFAYAGIKAAIFMHEKLLKKVMFAKFNFFDITSVG 1017
Query: 207 DLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMA 266
+++R SSD V S+ L+ A + G VG CV + P LG++
Sbjct: 1018 RILNRFSSDTNTVDDSLPFILNI-LLAQLAGLVG----------ALCVSLYAMPWLGLVI 1066
Query: 267 LVYGKRIRNLSRQLQTSVGELTKVSEEQLSA-----TKTIQAYCGEKKEIHRYADEVRKV 321
+ +L ++ + + ++ ++S +S T+T+Q + R + ++
Sbjct: 1067 IPMVPIYLSLQQRYRHASRDIKRLSSNAMSPLYTHFTETLQGLTTIRSM--RASPRFQRD 1124
Query: 322 FHVGLKEA----LTSGA----------FFGVTGFVGNVALLALLLTGTSMIKTGLMTVGD 367
F V L+E+ LT A G T VG LLA + T + GL+ +
Sbjct: 1125 FQVKLEESIKAQLTQSAAQQWLALRLQLLG-TLLVGGAGLLAAI-TASHTTNPGLVGL-- 1180
Query: 368 LSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARV---FELNDRK--------PLIHPTI 416
+ YA+ E + A R+ +L + + P PT
Sbjct: 1181 ---CISYALSITGQLGDLLHAVAETEQELVAVERIDQYLQLEEEQNASGSAEPPFGWPTQ 1237
Query: 417 GKDPVTLENKSIHFNHVKFSYPTRPQHHI---FEDLNFTVRPGEHVCIVGPSGGGKSTVA 473
G + F V+ SY + H+ + F E + IVG +G GK++V
Sbjct: 1238 GV---------LSFREVQLSY----REHLAPALRGITFQTEAFERIGIVGRTGAGKTSVL 1284
Query: 474 SLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELV 533
+ LLR + GEI+L N++ L R +GV+ QEP LF GT+ +N+ P+
Sbjct: 1285 AALLRVAPLTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENLD---PRHGF 1341
Query: 534 NDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILIL 593
D + I AI + L GL V G LS GQ+Q + LARA L + ++ +
Sbjct: 1342 YD-SEIWHAIKNSAAATLLVQQLGGLDGKVETCGNNLSAGQRQLLCLARALLKNAKVVAI 1400
Query: 594 DEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSF 653
DE TS LD +S+ + Q+L + + + T + IAHR+ + R+IVL+ G + E G+
Sbjct: 1401 DEGTSNLDDESDLSIQQAL-RNAFKSCTLLFIAHRLRGLHAMDRIIVLD-DGRICEEGNP 1458
Query: 654 DKLIAIPDSS 663
L + DSS
Sbjct: 1459 QSLAS--DSS 1466
Score = 83.6 bits (205), Expect = 1e-15
Identities = 67/248 (27%), Positives = 107/248 (43%), Gaps = 24/248 (9%)
Query: 392 LMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNF 451
+M+G+G + D PL P L+ K F H T P +D+N
Sbjct: 598 IMRGSGGSGA----GDDAPLDAPKAS----VLQMKCASFCHDS-DEQTSPTPFRMKDINV 648
Query: 452 TVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQ 511
++ G+ VCI GP GGGKS+ S ++ GE+ + ++ G V Q
Sbjct: 649 DIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGEVCV----------QELTTGFGYVPQ 698
Query: 512 EPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLS 571
P L GTI DNI + + + + + A + G VG G LS
Sbjct: 699 SPWLQRGTIRDNIVWGA-----QFDEQWYKTVLHACALEEDLQILGGDLVGVGENGRTLS 753
Query: 572 GGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVST 631
GGQ+ R+ALARA D + +LD+ S+LD+ + + R + KT I + +
Sbjct: 754 GGQRARVALARAVYQDKKVYLLDDVLSSLDAHVARHIIKHCILRLLKHKTRIVVTRNIQL 813
Query: 632 IQHSSRVI 639
H+++++
Sbjct: 814 FFHANQIL 821
>Hs5031915 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1325
Score = 121 bits (304), Expect = 3e-27
Identities = 116/495 (23%), Positives = 221/495 (44%), Gaps = 25/495 (5%)
Query: 157 GVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDA 216
G+ V L + R +++ L + ++ L+ F D N +G +++R S D
Sbjct: 770 GLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDI 829
Query: 217 GIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAP--PLGVMALVYGKRIR 274
G + + D + ++Q ++ +S + + + P PLG++ + +
Sbjct: 830 GHLDDLLPLTFLDFIQTLLQ------VVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFL 883
Query: 275 NLSRQLQ----TSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEAL 330
SR ++ T+ + L TI+AY E++ D + + L
Sbjct: 884 ETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEER-CQELFDAHQDLHSEAWFLFL 942
Query: 331 TSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXX 390
T+ +F V A+ +++ S+I + G + + YA+
Sbjct: 943 TTSRWFAVR-LDAICAMFVIIVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSA 1001
Query: 391 ELMKGAGAAARVFELNDRKPLIHPTIGKDPVTL--ENKSIHFNHVKFSY-PTRPQHHIFE 447
E+ + RV E D + K P I F++V F Y P P + +
Sbjct: 1002 EVENMMISVERVIEYTDLEKEAPWEYQKRPPPAWPHEGVIIFDNVNFMYSPGGPL--VLK 1059
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLG 507
L ++ E V IVG +G GKS++ S L R + G+I + + L R+ +
Sbjct: 1060 HLTALIKSQEKVGIVGRTGAGKSSLISALFRLSE-PEGKIWIDKILTTEIGLHDLRKKMS 1118
Query: 508 VVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRG 567
++ QEP+LF+GT+ N+ P + DE + A+ + + + + P + T + G
Sbjct: 1119 IIPQEPVLFTGTMRKNLD---PFKEHTDE-ELWNALQEVQLKETIEDLPGKMDTELAESG 1174
Query: 568 TQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAH 627
+ S GQ+Q + LARA L ILI+DEAT+ +D +++E++ + ++++ A T ++IAH
Sbjct: 1175 SNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAH-CTVLTIAH 1233
Query: 628 RVSTIQHSSRVIVLN 642
R++TI S +++VL+
Sbjct: 1234 RLNTIIDSDKIMVLD 1248
Score = 107 bits (267), Expect = 6e-23
Identities = 95/409 (23%), Positives = 175/409 (42%), Gaps = 35/409 (8%)
Query: 254 VMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHR 313
V+++L P + +GK +L + T + E ++ + I+ Y EK +
Sbjct: 243 VLIILLP----LQSCFGKLFSSLRSKTATFTDARIRTMNEVITGIRIIKMYAWEKSFSNL 298
Query: 314 YAD----EVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLS 369
+ E+ K+ + +FF + + V +L G+ + + + L
Sbjct: 299 ITNLRKKEISKILRSSCLRGMNLASFFSASKIIVFVTFTTYVLLGSVITASRVFVAVTLY 358
Query: 370 SFMMYAVXXXXXXXXXXXXXXEL-MKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSI 428
+ V + ++ + E++ R + P+ GK K +
Sbjct: 359 GAVRLTVTLFFPSAIERVSEAIVSIRRIQTFLLLDEISQRNRQL-PSDGK-------KMV 410
Query: 429 HFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIK 488
H + + + L+FTVRPGE + +VGP G GKS++ S +L GE+
Sbjct: 411 HVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVL-------GELA 463
Query: 489 LGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANC 548
+ L + V Q+P +FSGT+ NI + E + R + I
Sbjct: 464 PSH------GLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYE----KERYEKVIKACAL 513
Query: 549 TKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVV 608
K L DG T +G RGT LSGGQK R+ LARA D I +LD+ SA+D++ +
Sbjct: 514 KKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHL 573
Query: 609 AQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ + K TI + H++ ++ +S++++L + G + + G++ + +
Sbjct: 574 FELCICQILHEKITILVTHQLQYLKAASQILIL-KDGKMVQKGTYTEFL 621
>7301758 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1302
Score = 121 bits (304), Expect = 3e-27
Identities = 123/506 (24%), Positives = 217/506 (42%), Gaps = 50/506 (9%)
Query: 179 RLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGF 238
R+ R+ + + + F G +++R SSD + ++ Q + D +
Sbjct: 791 RISLRIHDQLFQGVIRAFMHFFTLATSGRILNRFSSDVLAIDVNLPQAMMDSIEFAVNAL 850
Query: 239 VGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSAT 298
++S T + LL P V+AL+YG R S T G T L+ T
Sbjct: 851 AVLAVVS------TANIWLLIPATVVVALLYGSRSPIYSHTNATFKGLAT---IRALNGT 901
Query: 299 KTIQAYCGEKKEIHRYADEVRKV--FHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTS 356
K ++ ++ H Y +E HV + A AF+ T + + +LA+ +
Sbjct: 902 KYME------RDFHYYQNENTSALYLHVSINRAF---AFW--TDLICVLYILAVTFSFLL 950
Query: 357 MIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTI 416
K GD+ + ++ EL + RV E + I
Sbjct: 951 FDKHRGYYSGDVGLAITQSMKLVLMCQAGMRQTVELENMMTSVERVME--------YVNI 1002
Query: 417 GKDPVTLENKSIH------------FNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGP 464
+P +S++ F ++ Y +I + L FT+R E + IVG
Sbjct: 1003 PSEPAYETEESVNLPKHWPSGGQLDFRDLRLRYSNHGP-YILKGLTFTIRGEEKIGIVGH 1061
Query: 465 SGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNI 524
+ GKS++ L R I +G I + L RR + ++ Q+P+LFSG++ N+
Sbjct: 1062 TAAGKSSIVHALFRLAHI-NGHISIDGFETSQLGLHDLRRRISIIPQDPVLFSGSLRFNL 1120
Query: 525 TYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAF 584
P E DE + A+ +F++N DG+ + G S GQ+Q + LARA
Sbjct: 1121 D---PFEEKTDE-ELWLALEAVKLKEFVSNLKDGINCRLHDCGANFSMGQRQLVCLARAL 1176
Query: 585 LLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRH 644
L ILI+DEAT+ +D +++ ++ +++ + A T ++IAHR+ T+ + RV+V++
Sbjct: 1177 LRQNKILIMDEATANVDPETDNLIQEAIHTKFAH-CTVLTIAHRLHTVMDNDRVMVVDM- 1234
Query: 645 GTVAETGSFDKLIAIPDSSLNKLLSK 670
G V E G +L+ L++ + K
Sbjct: 1235 GRVVELGHPHELLHNRHGYLHRFVEK 1260
Score = 103 bits (256), Expect = 1e-21
Identities = 72/236 (30%), Positives = 111/236 (46%), Gaps = 21/236 (8%)
Query: 424 ENKSIHFNHVKFSYPTRPQ---HHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYY 480
E KSI + + S+ + Q H ED++F + + V IVG G GKST+ ++L
Sbjct: 419 EVKSITVHKLSASWDQKKQEKRHRHIEDVSFQAQDQQFVGIVGTVGAGKSTLLQVILGEL 478
Query: 481 DIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRIS 540
DI SG +++ +L QEP L G++ DNI + P DE R
Sbjct: 479 DIISGSVEVNG-------------VLSYAPQEPWLLRGSLRDNILFTEPY----DEQRYL 521
Query: 541 RAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSAL 600
+ + + + P G T VG G LSGGQK R++LARA I +LD+ SA+
Sbjct: 522 EVLRVCHLDRDVEQLPLGDSTRVGEGGASLSGGQKARVSLARAVYRKADIYLLDDPLSAV 581
Query: 601 DSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
DS +++ K I + HRV ++H +++L G ++ G +D L
Sbjct: 582 DSHVSKMLLDRCLNEFLSKKIRILVTHRVQLLRHVDHLVLL-EGGRISVQGHYDAL 636
>At3g13100 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1248
Score = 120 bits (302), Expect = 5e-27
Identities = 124/518 (23%), Positives = 223/518 (42%), Gaps = 37/518 (7%)
Query: 169 RIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLS 228
R ++ +TG ++ L + +F D +G +++R S+D V + S
Sbjct: 735 RAMLSAMTGFKIATELFNQMHFRIFRASMSFFDATPIGRILNRASTDQSAVDLRLPSQFS 794
Query: 229 DGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELT 288
+ A + G+M ++W++ V + + Y R L+R S L
Sbjct: 795 NLAIAAVNILGIIGVMGQVAWQVLIVFIPVIAACTWYRQYYISAARELARLSGISRSPLV 854
Query: 289 KVSEEQLSATKTIQAYCGEKK---EIHRYADEVRKV-FHVGLKEALTSGAFFGVTGFVGN 344
+ E LS TI+++ E + +I R D ++ FH A+++ + + +
Sbjct: 855 QHFSETLSGITTIRSFDQEPRFRTDIMRLNDCYSRLRFH-----AISAMEWLCFRLDLLS 909
Query: 345 VALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFE 404
AL L + G++ + YA+ +L + R+ +
Sbjct: 910 TVAFALSLVILVSVPEGVINPSFAGLAVTYALNLNSLQATLIWTLCDLENKMISVERMLQ 969
Query: 405 LND------------RKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFT 452
D R P G+ +T+ N + + P P + L T
Sbjct: 970 YIDIPSEPSLVIESTRPEKSWPCRGE--ITICNLQVRYG------PHLPM--VLRGLTCT 1019
Query: 453 VRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQE 512
R G IVG +G GKST+ L R + +GEI++ NI L R L ++ QE
Sbjct: 1020 FRGGLKTGIVGRTGCGKSTLIQTLFRIVEPAAGEIRIDGINILTIGLHDLRSRLSIIPQE 1079
Query: 513 PMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSG 572
P +F GT+ N+ P E D+ +I A+ + + L + V G S
Sbjct: 1080 PTMFEGTVRSNLD---PLEEYADD-QIWEALDKCQLGDEIRKKELKLDSPVSENGQNWSV 1135
Query: 573 GQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTI 632
GQ+Q + L R L +LILDEAT+++D+ ++ ++ ++L+Q + G T I+IAHR+S++
Sbjct: 1136 GQRQLVCLGRVLLKRSKVLILDEATASVDTATDTLIQETLRQHFS-GCTVITIAHRISSV 1194
Query: 633 QHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
S V++L++ G + E S +L+ SS +KL+++
Sbjct: 1195 IDSDMVLLLDQ-GLIEEHDSPARLLEDKSSSFSKLVAE 1231
Score = 92.4 bits (228), Expect = 2e-18
Identities = 60/223 (26%), Positives = 108/223 (47%), Gaps = 18/223 (8%)
Query: 435 FSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNI 494
FS+ +D+ F + G ++ I G G GKS++ S +L GE+ + N+
Sbjct: 386 FSWDDSSPIPTLKDIRFKIPHGMNIAICGTVGSGKSSLLSSIL-------GEVPKISGNL 438
Query: 495 RDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLAN 554
+ + Y + Q P + SG + +NI + P + R + + K L
Sbjct: 439 KVCGRKAY------IAQSPWIQSGKVEENILFGKPMQ----REWYQRVLEACSLNKDLEV 488
Query: 555 FPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQ 614
FP QT +G RG LSGGQKQRI +ARA D I + D+ SA+D+ + + + +
Sbjct: 489 FPFRDQTVIGERGINLSGGQKQRIQIARALYQDADIYLFDDPFSAVDAHTGSHLFKEVLL 548
Query: 615 RSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
R KT I + H++ + + ++V+ + G + + G +++++
Sbjct: 549 GLLRNKTVIYVTHQLEFLPEADLILVM-KDGRITQAGKYNEIL 590
>At1g30410 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1495
Score = 120 bits (302), Expect = 5e-27
Identities = 132/537 (24%), Positives = 224/537 (41%), Gaps = 42/537 (7%)
Query: 156 GGVFVVGALANVGRIVILKVTGERLVA-------RLRTRTMKAALEQDATFLDHNRVGDL 208
G VV AL G++ + L+ RL + + L F N G +
Sbjct: 950 GFYIVVYALLGFGQVAVTFTNSFWLITSSLHAARRLHDAMLSSILRAPMLFFHTNPTGRV 1009
Query: 209 ISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALV 268
I+R S D G + ++V ++ + Q F ++ +S +M L L
Sbjct: 1010 INRFSKDIGDIDRNVANLMNMFMNQLWQLLSTFALIGTVSTISLWAIMPLLILFYAAYLY 1069
Query: 269 YGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKE 328
Y R + R + + E L+ +I+AY K R A K ++
Sbjct: 1070 YQSTSREVRRLDSVTRSPIYAQFGEALNGLSSIRAY----KAYDRMAKINGKSMDNNIRF 1125
Query: 329 ALTSGA-----------FFGVTGFVGNVALLALLLTGTSMIKTGLM-TVGDLSSFMMYAV 376
L + + GV + A A+L G + + G T+G L S+ +
Sbjct: 1126 TLANTSSNRWLTIRLETLGGV--MIWLTATFAVLQNGNTNNQAGFASTMGLLLSYTLNIT 1183
Query: 377 XXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLI----HPTIGKDPVTLENKSIHFNH 432
+ +L I P G SI F
Sbjct: 1184 SLLSGVLRQASRAENSLNSVERVGNYIDLPSEATDIIENNRPVCGWP----SGGSIKFED 1239
Query: 433 VKFSY-PTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGN 491
V Y P P + L F V P E V +VG +G GKS++ + L R ++ G I + +
Sbjct: 1240 VHLRYRPGLPP--VLHGLTFFVSPSEKVGVVGRTGAGKSSMLNALFRIVEVEKGRIMIDD 1297
Query: 492 DNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKF 551
++ F L RR+L ++ Q P+LFSGT+ NI P ND + A+ +A+
Sbjct: 1298 CDVAKFGLTDVRRVLSIIPQSPVLFSGTVRFNID---PFSEHND-AGLWEALHRAHIKDV 1353
Query: 552 LANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQS 611
++ P GL V G S GQ+Q ++LARA L IL+LDEAT+++D +++ ++ ++
Sbjct: 1354 ISRNPFGLDAEVCEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDVRTDSLIQRT 1413
Query: 612 LQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLL 668
+++ + T + IAHR++TI +++VL+ G V E S +L++ S+ +++
Sbjct: 1414 IRE-EFKSCTMLVIAHRLNTIIDCDKILVLS-SGQVLEYDSPQELLSRDTSAFFRMV 1468
Score = 85.5 bits (210), Expect = 3e-16
Identities = 117/497 (23%), Positives = 205/497 (40%), Gaps = 56/497 (11%)
Query: 179 RLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGF 238
R+ RLR+ T+ AA+ + L H +R + +G V+ +T + ++ + + Q
Sbjct: 367 RVGFRLRS-TLVAAIFHKSLRLTHE------ARKNFASGKVTNMITTD-ANALQQISQQL 418
Query: 239 VGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSV----GELTK----- 289
G F ++ M+LL LGV +L +G I L LQT + +LTK
Sbjct: 419 HGLWSAPF---RIIVSMILLYQQLGVASL-FGSLILFLLIPLQTLIISKMRKLTKEGLQW 474
Query: 290 ------VSEEQLSATKTIQAYCGEKKEIHRYA----DEVRKVFHVGLKEALTSGAFFGVT 339
++ E LS+ T++ Y EK R +E+ L A S +
Sbjct: 475 TDKRVGITNEILSSMDTVKCYAWEKSFESRIQGIRNEELSWFRKAQLLSAFNSFILNSIP 534
Query: 340 GFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAA 399
V V+ +L G + T L + + + + +++ +
Sbjct: 535 VVVTVVSFGVFVLLGGDLTPARAFTSLSLFAVLRFPLNMLPNLLS------QVVNANVSL 588
Query: 400 ARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHV 459
R+ EL + I P+ +I + FS+ ++ D+N + G V
Sbjct: 589 QRIEELLLSEERI--LAQNPPLQPGTPAISIKNGYFSWDSKTTKPTLSDINLEIPVGTLV 646
Query: 460 CIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGT 519
IVG +G GK+++ S +L G + + R + V Q +F+ T
Sbjct: 647 AIVGGTGEGKTSLISAML------------GELSHAETTSVVIRGSVAYVPQVSWIFNAT 694
Query: 520 ILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIA 579
+ +NI + E R RAI L P T +G RG +SGGQKQR++
Sbjct: 695 VRENILFGSDFE----SERYWRAIDATALQHDLDLLPGRDLTEIGERGVNISGGQKQRVS 750
Query: 580 LARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVI 639
+ARA + + I D+ SALD+ V S + RGKT + + +++ + ++I
Sbjct: 751 MARAVYSNSDVYIFDDPLSALDAHVAHQVFDSCMKDELRGKTRVLVTNQLHFLPLMDKII 810
Query: 640 VLNRHGTVAETGSFDKL 656
+++ G + E G+F +L
Sbjct: 811 LVS-EGMIKEEGTFVEL 826
>7297980 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1896
Score = 119 bits (299), Expect = 1e-26
Identities = 115/479 (24%), Positives = 205/479 (42%), Gaps = 20/479 (4%)
Query: 189 MKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFIS 248
++ L T D VG ++SR S D V + + Q ++D + ++S +
Sbjct: 1423 LENVLRAPMTMFDTTPVGRILSRFSKDVESVDQKMPQVINDCIWCAFEVLATIVVISLST 1482
Query: 249 WKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEK 308
V++ +A Y R L R S + E ++ TI+AY
Sbjct: 1483 PIFLAVIVPIAFLYYFAQRFYVATSRQLMRLESVSRSPIYSHFSETVTGASTIRAYNVGD 1542
Query: 309 KEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDL 368
+ I +V K + + VGN L +L + G G +
Sbjct: 1543 RFIEESDAKVDKNQVCKYPSVIANRWLAIRLEMVGN---LIILFASLFAVLGGQTNPGLV 1599
Query: 369 SSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLEN--- 425
+ YA+ ++ + R+ E + K + +D +N
Sbjct: 1600 GLSVSYALQVTQTLNWLVRMSSDIETNIVSVERIKEYGETKQEAPWELEQDKNKPKNWPQ 1659
Query: 426 -KSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGS 484
+ F + + Y + ++F ++ GE V IVG +G GKS++ L R +
Sbjct: 1660 EGRVEFQNFQVRY-REGLDLVLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAG 1718
Query: 485 GEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIG 544
G I + +I L R L ++ Q+P+LFSG++ N+ P E+ D+ I +A+
Sbjct: 1719 GRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLD---PFEIKTDD-EIWKALE 1774
Query: 545 QANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQS 604
++ F+ + GL + G LS GQ+Q + LARA L +L+LDEAT+A+D ++
Sbjct: 1775 LSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLET 1834
Query: 605 EEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSS 663
++++ + T ++IAHR++TI S +VIVL++ G + E S +L+ P S+
Sbjct: 1835 DDLI-------QFKECTVLTIAHRLNTILDSDKVIVLDK-GQIIEFASPTELLDNPKSA 1885
Score = 82.4 bits (202), Expect = 2e-15
Identities = 112/503 (22%), Positives = 199/503 (39%), Gaps = 62/503 (12%)
Query: 175 VTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAV 234
+ G R+ L + AL + + VG++++ ++ DA + +T L+ A
Sbjct: 399 IVGLRIRTALINAIYRKALRISNSTKKESTVGEIVNLMAVDAQRFME-LTTYLNMIWSAP 457
Query: 235 IQGFVGFGMMSFISWKLT--------CVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGE 286
+Q G+ + W+ VM++L P GV+A RI+ + E
Sbjct: 458 LQ----IGLALYFLWQQLGPSVLAGLAVMIILIPVNGVIA----SRIKTYQIRQMKYKDE 509
Query: 287 LTKVSEEQLSATKTIQAYCGE---KKEIHRYAD-EVRKVFHVGLKEALTSGAFFGVTGFV 342
K+ E LS K ++ Y E +K++ D E+ + A TS + V
Sbjct: 510 RVKLMNEVLSGIKVLKLYAWEPSFEKQVLDIRDKEIATLRSTAYLNAGTSFLWSCAPFLV 569
Query: 343 GNVALLALLLTGTSMIKTGLMTVGDLSSF--MMYAVXXXXXXXXXXXXXXELMKGAGAAA 400
V +L + + T LS F + + + +
Sbjct: 570 SLVTFATYVLIDENNVLDATKTFVSLSLFNILRFPLTMLPMLITNLVQTQVSVNRINKFL 629
Query: 401 RVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVC 460
EL D ++H + P+++EN + ++N V+ G V
Sbjct: 630 NSEEL-DPNSVLHDSSKPHPMSIENGEFSWG----------DEITLRNINIEVKKGSLVA 678
Query: 461 IVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTI 520
+VG G GKS+V L + +G + L V Q+ + + T+
Sbjct: 679 LVGTVGSGKSSVVQAFLGEMEKLAGVVNTVGK-------------LAYVPQQAWIQNATV 725
Query: 521 LDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIAL 580
DNI + D R ++ I + G T +G +G LSGGQKQRI+L
Sbjct: 726 RDNILFGQTY----DRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISL 781
Query: 581 ARAFLLDPSILILDEATSALDSQ-----SEEVVA-QSLQQRSARGKTTISIAHRVSTIQH 634
ARA D + +LD+ SA+D+ EEV+ + + R +R + + H V+ +
Sbjct: 782 ARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSR----VLVTHGVTFLPQ 837
Query: 635 SSRVIVLNRHGTVAETGSFDKLI 657
+ V+ + G ++E+G+FD+L+
Sbjct: 838 VDSIYVI-KMGEISESGTFDQLV 859
>7298518 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1307
Score = 119 bits (298), Expect = 2e-26
Identities = 75/242 (30%), Positives = 134/242 (54%), Gaps = 29/242 (11%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+ + L+FT++P E V IVG +G GKS++ + L R G I + + + D L R
Sbjct: 1067 VLKGLSFTIQPMEKVGIVGRTGAGKSSLINALFRL-SYNDGAILIDSLDTNDIGLHDLRS 1125
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
+ ++ QEP+LFSGT+ N+ P E D+ ++ +A+ + + ++ P GLQ+ +
Sbjct: 1126 KISIIPQEPVLFSGTMRYNLD---PFEQYPDD-KLWKALEDVHLKEEISELPSGLQSIIS 1181
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
GT S GQ+Q + LARA L + IL++DEAT+ +D Q++ ++ +++ + + T ++
Sbjct: 1182 EGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDALIQATIRNK-FKDCTVLT 1240
Query: 625 IAHRVSTIQHSSRVIVLNR---------------------HGTVAETG--SFDKLIAIPD 661
IAHR++TI S +V+V++ HG V +TG SFD L+ + +
Sbjct: 1241 IAHRLNTIMDSDKVLVMDAGHVVEFGSPYELLTASKAKVFHGMVMQTGKASFDHLLKVAE 1300
Query: 662 SS 663
++
Sbjct: 1301 NT 1302
Score = 88.6 bits (218), Expect = 3e-17
Identities = 63/246 (25%), Positives = 118/246 (47%), Gaps = 31/246 (12%)
Query: 416 IGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASL 475
IGK+P TL + ++ + + ++N ++R G+ V ++GP G GKS++
Sbjct: 426 IGKEPDTL----VEIKALRARWGQEQHDLVLNNVNMSLRRGQLVAVIGPVGSGKSSLIQA 481
Query: 476 LLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVND 535
+L SG +++ KY QEP LF+ ++ DNI + +P +
Sbjct: 482 ILGELPPESGSVQVSG---------KY----SYASQEPWLFNASVRDNILFGLPMDKQRY 528
Query: 536 ETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDE 595
T + R + + G T VG RG LSGGQ+ RI LARA + +LD+
Sbjct: 529 RTVLKRCALERDLELL-----HGDGTIVGERGASLSGGQRARICLARAVYRRADVYLLDD 583
Query: 596 ATSALDSQSEEVVAQSLQQRSARG----KTTISIAHRVSTIQHSSRVIVLNRHGTVAETG 651
SA+D+ V + L RG + I + H++ ++ + ++++++ G V+ G
Sbjct: 584 PLSAVDTH----VGRHLFDECMRGFLGKQLVILVTHQLQFLEDADLIVIMDK-GHVSACG 638
Query: 652 SFDKLI 657
++++++
Sbjct: 639 TYEEML 644
>Hs9955970 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1527
Score = 119 bits (297), Expect = 2e-26
Identities = 78/214 (36%), Positives = 123/214 (57%), Gaps = 6/214 (2%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+ DL+ V GE V IVG +G GKS++ L R + GEI++ N+ D L R
Sbjct: 1305 VLRDLSLHVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRS 1364
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
L ++ Q+P+LFSGT+ N+ P ++E I A+ ++ F+++ P GL
Sbjct: 1365 QLTIIPQDPILFSGTLRMNLD---PFGSYSEED-IWWALELSHLHTFVSSQPAGLDFQCS 1420
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
G LS GQ+Q + LARA L IL+LDEAT+A+D +++ ++ +++ + T ++
Sbjct: 1421 EGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATIRTQFDT-CTVLT 1479
Query: 625 IAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
IAHR++TI +RV+VL++ G VAE S LIA
Sbjct: 1480 IAHRLNTIMDYTRVLVLDK-GVVAEFDSPANLIA 1512
Score = 82.4 bits (202), Expect = 2e-15
Identities = 71/259 (27%), Positives = 118/259 (45%), Gaps = 31/259 (11%)
Query: 419 DPVTLENKSI--------HFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKS 470
DP ++E K+I H ++ P H L+ V G V +VGP G GKS
Sbjct: 612 DPQSVERKTISPGYAITIHSGTFTWAQDLPPTLH---SLDIQVPKGALVAVVGPVGCGKS 668
Query: 471 TVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQ 530
++ S LL + G++ + + V Q+ + + T+ +N+ +
Sbjct: 669 SLVSALLGEMEKLEGKVHMKGS-------------VAYVPQQAWIQNCTLQENVLFG--- 712
Query: 531 ELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSI 590
+ +N + R + + L P G QT +G +G LSGGQ+QR++LARA D I
Sbjct: 713 KALNPK-RYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADI 771
Query: 591 LILDEATSALDSQSEEVVAQSL--QQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVA 648
+LD+ SA+DS + + + + GKT + + H +S + + +IVL G V+
Sbjct: 772 FLLDDPLSAVDSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVL-ADGQVS 830
Query: 649 ETGSFDKLIAIPDSSLNKL 667
E G + L+ S N L
Sbjct: 831 EMGPYPALLQRNGSFANFL 849
>ECU01g1410 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC superfamily
Length = 596
Score = 118 bits (296), Expect = 3e-26
Identities = 114/440 (25%), Positives = 188/440 (41%), Gaps = 75/440 (17%)
Query: 252 TCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEI 311
TCVM+ + Y K I N + + E +S ++A C E+ E+
Sbjct: 187 TCVMLRIRAR-------YRKEINNADNSVSRRIHEC-------VSNVDLVRACCSEQFEV 232
Query: 312 HRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLT-----GTSMIKTGLMTVG 366
R A E+ ++ + L + G+T +G AL ++L G + + MTVG
Sbjct: 233 SRLAGEMETMWALKLSDK----GCVGMTN-LGQRALFSVLFVHVAFKGIADMAALRMTVG 287
Query: 367 DLSSFMMYAVXXXXXXXXXXXXXXELM-----------------------KGAGAAARVF 403
DLS + + +L GAGAAA
Sbjct: 288 DLSVLFSFVLSIDASMWTLGGIARDLGFWLTDCTDLLCLHDGLERAAEQGPGAGAAAEGM 347
Query: 404 ELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQH----HIFEDLNFTVRPGEHV 459
P E ++ F+ V F+YP + H+ ++F + GE V
Sbjct: 348 AACPSSP-----------PGEAAAVEFDDVSFAYPRSAAYPRSAHVLSGVSFRIMRGERV 396
Query: 460 CIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGT 519
I+G G GKST+ L+L + G I++ + + R R +G + Q+ +LF +
Sbjct: 397 GIIGRPGSGKSTILRLILMLHR-HKGRIRVNGAELWSASPRAVRGSIGCILQDGLLFDES 455
Query: 520 ILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIA 579
IL N+ Y P+ + R + G ++ + GL + R LSGG+ Q ++
Sbjct: 456 ILYNVMYGCPRAGFHRVLRECKNAGLSDVVR-----RKGLHS----RMKALSGGEMQMVS 506
Query: 580 LARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVI 639
LAR FL D +++LDEATS LD+++E V + RGKT + + H + +H RVI
Sbjct: 507 LARCFLKDAPLMLLDEATSKLDAETERDVFGLMM--GMRGKTIVMVLHDLWMTEHLDRVI 564
Query: 640 VLNRHGTVAETGSFDKLIAI 659
+++ GTV E G+ +L+ +
Sbjct: 565 LVD-SGTVKEVGTHSELMGL 583
>ECU01g0200 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC superfamily
Length = 596
Score = 118 bits (296), Expect = 3e-26
Identities = 114/440 (25%), Positives = 188/440 (41%), Gaps = 75/440 (17%)
Query: 252 TCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEI 311
TCVM+ + Y K I N + + E +S ++A C E+ E+
Sbjct: 187 TCVMLRIRAR-------YRKEINNADNSVSRRIHEC-------VSNVDLVRACCSEQFEV 232
Query: 312 HRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLT-----GTSMIKTGLMTVG 366
R A E+ ++ + L + G+T +G AL ++L G + + MTVG
Sbjct: 233 SRLAGEMETMWALKLSDK----GCVGMTN-LGQRALFSVLFVHVAFKGIADMAALRMTVG 287
Query: 367 DLSSFMMYAVXXXXXXXXXXXXXXELM-----------------------KGAGAAARVF 403
DLS + + +L GAGAAA
Sbjct: 288 DLSVLFSFVLSIDASMWTLGGIARDLGFWLTDCTDLLCLHDGLERAAEQGPGAGAAAEGM 347
Query: 404 ELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQH----HIFEDLNFTVRPGEHV 459
P E ++ F+ V F+YP + H+ ++F + GE V
Sbjct: 348 AACPSSP-----------PGEAAAVEFDDVSFAYPRSAAYPRSAHVLSGVSFRIMRGERV 396
Query: 460 CIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGT 519
I+G G GKST+ L+L + G I++ + + R R +G + Q+ +LF +
Sbjct: 397 GIIGRPGSGKSTILRLILMLHR-HKGRIRVNGAELWSASPRAVRGSIGCILQDGLLFDES 455
Query: 520 ILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIA 579
IL N+ Y P+ + R + G ++ + GL + R LSGG+ Q ++
Sbjct: 456 ILYNVMYGCPRAGFHRVLRECKNAGLSDVVR-----RKGLHS----RMKALSGGEMQMVS 506
Query: 580 LARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVI 639
LAR FL D +++LDEATS LD+++E V + RGKT + + H + +H RVI
Sbjct: 507 LARCFLKDAPLMLLDEATSKLDAETERDVFGLMM--GMRGKTIVMVLHDLWMTEHLDRVI 564
Query: 640 VLNRHGTVAETGSFDKLIAI 659
+++ GTV E G+ +L+ +
Sbjct: 565 LVD-SGTVKEVGTHSELMGL 583
>At3g13080 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1514
Score = 118 bits (295), Expect = 4e-26
Identities = 115/508 (22%), Positives = 215/508 (41%), Gaps = 17/508 (3%)
Query: 169 RIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLS 228
R +L G + L + +F D G ++SR S+D V +
Sbjct: 1008 RATLLVTAGYKTATELFHKMHHCIFRSPMSFFDSTPSGRIMSRASTDQSAVDLELPYQFG 1067
Query: 229 DGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELT 288
VIQ G+MS +SW + V + + Y R LSR + L
Sbjct: 1068 SVAITVIQLIGIIGVMSQVSWLVFLVFIPVVAASIWYQRYYIAAARELSRLVGVCKAPLI 1127
Query: 289 KVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALL 348
+ E +S TI+++ +E +D +R + T+GA + + ++ L
Sbjct: 1128 QHFSETISGATTIRSF---SQEFRFRSDNMRLSDGYSRPKFYTAGAMEWLCFRLDMLSSL 1184
Query: 349 ALLLTGTSMIK--TGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFE-- 404
+ + ++ TG++ + Y + L + R+ +
Sbjct: 1185 TFVFSLVFLVSIPTGVIDPSLAGLAVTYGLSLNTLQAWLIWTLCNLENKIISVERILQYA 1244
Query: 405 -LNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSY-PTRPQHHIFEDLNFTVRPGEHVCIV 462
+ PL+ + + + ++ Y P P + + T + G IV
Sbjct: 1245 SVPSEPPLVIESNRPEQSWPSRGEVEIRDLQVRYAPHMPL--VLRGITCTFKGGLRTGIV 1302
Query: 463 GPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILD 522
G +G GKST+ L R + +GEI++ NI L R L ++ Q+P +F GT+
Sbjct: 1303 GRTGSGKSTLIQTLFRIVEPSAGEIRIDGVNILTIGLHDLRLRLSIIPQDPTMFEGTMRS 1362
Query: 523 NITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALAR 582
N+ P E D+ +I A+ + + L ++V G S GQ+Q + L R
Sbjct: 1363 NLD---PLEEYTDD-QIWEALDKCQLGDEVRKKEQKLDSSVSENGDNWSMGQRQLVCLGR 1418
Query: 583 AFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLN 642
L IL+LDEAT+++D+ ++ ++ ++L++ + T I+IAHR+S++ S V++L+
Sbjct: 1419 VLLKRSKILVLDEATASVDTATDNLIQKTLREHFS-DCTVITIAHRISSVIDSDMVLLLS 1477
Query: 643 RHGTVAETGSFDKLIAIPDSSLNKLLSK 670
+G + E + +L+ SS +KL+++
Sbjct: 1478 -NGIIEEYDTPVRLLEDKSSSFSKLVAE 1504
Score = 95.9 bits (237), Expect = 2e-19
Identities = 64/222 (28%), Positives = 109/222 (48%), Gaps = 18/222 (8%)
Query: 436 SYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIR 495
S+ + +D+NF V PG V + G G GKS++ S LL GE+ + +++
Sbjct: 648 SWDVSSSNPTLKDINFKVFPGMKVAVCGTVGSGKSSLLSSLL-------GEVPKVSGSLK 700
Query: 496 DFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANF 555
+ Y V Q P + SG I DNI + P E R + + + +K L
Sbjct: 701 VCGTKAY------VAQSPWIQSGKIEDNILFGKPME----RERYDKVLEACSLSKDLEIL 750
Query: 556 PDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQR 615
G QT +G RG LSGGQKQRI +ARA D I + D+ SA+D+ + + + +
Sbjct: 751 SFGDQTVIGERGINLSGGQKQRIQIARALYQDADIYLFDDPFSAVDAHTGSHLFKEVLLG 810
Query: 616 SARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
K+ I + H+V + + ++V+ + G +++ G ++ ++
Sbjct: 811 LLCSKSVIYVTHQVEFLPAADLILVM-KDGRISQAGKYNDIL 851
>7300555 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1348
Score = 118 bits (295), Expect = 4e-26
Identities = 110/468 (23%), Positives = 212/468 (44%), Gaps = 28/468 (5%)
Query: 199 FLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFIS--WKLTCVMM 256
F + N G +++R S D G V + + + D + VG ++ I W + +
Sbjct: 846 FFNTNPSGRILNRFSKDLGQVDEILPSVMMD-VMQIFLAIVGIVVVLCIINVWYILATVF 904
Query: 257 LLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYAD 316
L+ ++ + Y R++ R + + L+ TI+A+ G +KE+ D
Sbjct: 905 LVIV-FYLLRVFYLSTSRDVKRLEAVTRSPIYSHLSASLNGLATIRAF-GAQKELIAEFD 962
Query: 317 EVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAV 376
+ + G L + FG ++ V ++ + + S GD+ A+
Sbjct: 963 NYQDMHSSGYYMFLATSRAFGY--WLDCVCVVYIAVITLSFFLFSPENGGDVG----LAI 1016
Query: 377 XXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFS 436
E ++ G + N + P P GK + ++ S+ +
Sbjct: 1017 TQAMGMTVERVVEYEDLEPEGDFES--KPNKKPPKDWPEDGK--IVFDDLSLKY------ 1066
Query: 437 YPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRD 496
+P + ++ LN + E V IVG +G GKS++ + L R G I + + D
Sbjct: 1067 FPDKAADYVLRSLNIAIEGCEKVGIVGRTGAGKSSLINALFRL-SYNEGAILIDRRDTND 1125
Query: 497 FNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFP 556
L R + ++ QEP+LFSGT+ N+ P + +D ++ ++ + + +A+ P
Sbjct: 1126 LGLHDLRSKISIIPQEPVLFSGTMRYNLD---PFDEYSD-AKLWESLEEVKLKQVVADLP 1181
Query: 557 DGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRS 616
GLQ+ + GT S GQ+Q + LARA L + IL++DEAT+ +D Q++ ++ +++ +
Sbjct: 1182 SGLQSKISEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDALIQTTIRNK- 1240
Query: 617 ARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSL 664
+ T ++IAHR+ T+ S +V+V++ G E GS +L+ + +
Sbjct: 1241 FKDCTVLTIAHRLHTVMDSDKVLVMDA-GKAVEFGSPFELLTTSEKKV 1287
Score = 99.4 bits (246), Expect = 2e-20
Identities = 109/513 (21%), Positives = 206/513 (39%), Gaps = 65/513 (12%)
Query: 182 ARLRTRTM--KAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFV 239
AR+ +M + AL T L +G +++ +S+D G + SV + G V
Sbjct: 168 ARIAMTSMIYRKALRLSRTALGDTTIGQVVNLISNDVGRLDVSVIH-----MNYLWLGPV 222
Query: 240 GFGMMSFISWKL--------TCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVS 291
G+++++ ++ VM+L P + GK+ L + E ++
Sbjct: 223 EIGIITYLMYREIGISAFFGVAVMLLFIP----LQAYLGKKTSVLRLKTALRTDERVRMM 278
Query: 292 EEQLSATKTIQAYCGE-----------KKEIH--RYADEVRKVFHVGLKEALTSGAFFGV 338
E +S + I+ Y E KE++ R + +R + F +
Sbjct: 279 NEIISGIQVIKMYAWEIPFSKMINYVRTKEMNAIRNVNYIRGTLQSFIMFVTRISVFVSL 338
Query: 339 TGFVGNVALL----ALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMK 394
GFV LL A ++T I MTV +A E K
Sbjct: 339 VGFVLLGKLLTAEKAFVITAYYNILRNTMTVYFPMGISQFAELLVSIRRIQTFMLHEETK 398
Query: 395 GAGAAARVFE--LNDRKPLIHPTIGKDPVTLE---------NKSIHFNHVKFSYPTRPQH 443
+ + E L + PT+ + L+ SI + +K + +
Sbjct: 399 VRDKSEDLDEQKLGKAGLIAEPTVAQTTGVLKPSSRRTSEAEHSIVISKLKAKWDQKNTD 458
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYR 503
+ ++++ +P + V ++GP G GKS++ +L + SG +K+
Sbjct: 459 NTLDNISLKFKPRQLVAVIGPVGSGKSSLIQAVLGELNPDSGSVKVNGT----------- 507
Query: 504 RLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTV 563
L QEP LF+GT+ NI + +P D+ R + + + P +T V
Sbjct: 508 --LSYASQEPWLFTGTVRQNILFGLPM----DKHRYRTVVKRCALERDFELLPYADKTIV 561
Query: 564 GPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTI 623
G RG LSGGQK RI+LARA I +LD+ SA+D+ + + R + +
Sbjct: 562 GERGASLSGGQKARISLARAVYRKADIYLLDDPLSAVDTHVGRHLFDQCMRGFLREEIVL 621
Query: 624 SIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
+ H++ ++ + ++++++ G ++ G+++ +
Sbjct: 622 LVTHQLQFLEQADVIVIMDK-GKISAMGTYESM 653
>At3g60160 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1490
Score = 116 bits (291), Expect = 1e-25
Identities = 128/538 (23%), Positives = 223/538 (40%), Gaps = 58/538 (10%)
Query: 155 LGGVFVVGALANVG-------RIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGD 207
+G + +V AL G R +++ + G +R + + +F D G
Sbjct: 973 MGRILLVYALLAAGSSLCVLARTILVAIGGLSTAETFFSRMLCSIFRAPMSFFDSTPTGR 1032
Query: 208 LISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMAL 267
+++R S+D ++ + L ++IQ +MS ++W+
Sbjct: 1033 ILNRASTDQSVLDLEMAVKLGWCAFSIIQIVGTIFVMSQVAWQR---------------- 1076
Query: 268 VYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYA----DEVRKVFH 323
Y R LSR + E L+ TI+A+ + I R FH
Sbjct: 1077 YYTPTARELSRMSGVERAPILHHFAESLAGATTIRAFDQRDRFISSNLVLIDSHSRPWFH 1136
Query: 324 VGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGD--------LSSFMMYA 375
V S ++ FV +L+ L+ +I + +G L + +++
Sbjct: 1137 VASAMEWLSFRLNLLSHFVFAFSLVLLVTLPEGVINPSIAGLGVTYGLSLNVLQATVIWN 1196
Query: 376 VXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIH-PTIGKDPVTLENKSIHFNHVK 434
+ + K A V ++ +PL + P +G SI F ++
Sbjct: 1197 ICNAENKMISVERILQYSKIPSEAPLV--IDGHRPLDNWPNVG---------SIVFRDLQ 1245
Query: 435 FSYPTRPQHH--IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGND 492
Y +H + +++ G+ + +VG +G GKST+ L R + G I + N
Sbjct: 1246 VRYA---EHFPAVLKNITCEFPGGKKIGVVGRTGSGKSTLIQALFRIVEPSQGTIVIDNV 1302
Query: 493 NIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFL 552
+I L R LG++ Q+P LF GTI N+ P D I AI + +
Sbjct: 1303 DITKIGLHDLRSRLGIIPQDPALFDGTIRLNLD---PLAQYTDH-EIWEAIDKCQLGDVI 1358
Query: 553 ANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSL 612
+ L TV G S GQ+Q + L R L +IL+LDEAT+++DS ++ V+ Q +
Sbjct: 1359 RAKDERLDATVVENGENWSVGQRQLVCLGRVLLKKSNILVLDEATASVDSATDGVI-QKI 1417
Query: 613 QQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
+ + +T ++IAHR+ T+ S V+VL+ G +AE S KL+ DS +KL+ +
Sbjct: 1418 INQEFKDRTVVTIAHRIHTVIESDLVLVLS-DGRIAEFDSPAKLLQREDSFFSKLIKE 1474
Score = 99.4 bits (246), Expect = 2e-20
Identities = 93/406 (22%), Positives = 169/406 (40%), Gaps = 30/406 (7%)
Query: 258 LAPPLGVMALVYG--KRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYA 315
L L VMA Y + RN + + + K + E L K ++ + + +++
Sbjct: 460 LVTTLMVMACNYPLTRLQRNYQSDIMNAKDDRMKATSEILKNMKILKLQAWDNQFLNKVK 519
Query: 316 DEVRKVFHVGLK----EALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSF 371
+K + K +A T+ +G + V + +L G + +++ L++F
Sbjct: 520 TLRKKEYDCLWKSLRLQAFTTFILWGAPSLISVVTFVTCMLMGVKLTAGAVLSA--LATF 577
Query: 372 MMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFN 431
M + A+ + + +K + KD L S+
Sbjct: 578 QMLQSPIFGLPDLLSALVQSKVSADRIASYLQQSETQKDAVE-YCSKDHTEL---SVEIE 633
Query: 432 HVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGN 491
+ FS+ +D+ V+ G V + G G GKS++ S +L GEI+
Sbjct: 634 NGAFSWEPESSRPTLDDIELKVKSGMKVAVCGAVGSGKSSLLSSIL-------GEIQKLK 686
Query: 492 DNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKF 551
+R + Y V Q P + SGTI DNI + E + R + K
Sbjct: 687 GTVRVSGKQAY------VPQSPWILSGTIRDNILFGSMYE----SEKYERTVKACALIKD 736
Query: 552 LANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQS 611
F +G T +G RG +SGGQKQRI +ARA + I +LD+ SA+D+ + + +
Sbjct: 737 FELFSNGDLTEIGERGINMSGGQKQRIQIARAVYQNADIYLLDDPFSAVDAHTGRELFED 796
Query: 612 LQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ KT + + H+V + + ++V+ ++G V + G F++L+
Sbjct: 797 CLMGILKDKTVLYVTHQVEFLPAADLILVM-QNGRVMQAGKFEELL 841
>CE09548 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1573
Score = 116 bits (290), Expect = 1e-25
Identities = 130/502 (25%), Positives = 223/502 (43%), Gaps = 35/502 (6%)
Query: 184 LRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGM 243
L M+ F D G +++R+ D V + N+ + ++Q V +
Sbjct: 1088 LHAPLMRNLFRVPMAFYDTTPFGRILNRIGKDIETVDVLLPFNVQFFAQCLLQ-VVSTLI 1146
Query: 244 MSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVS-----EEQLSAT 298
+ IS T V ++ PL VM L+ + SRQL+ + +T+ E + +
Sbjct: 1147 IIMIS---TPVFGIVIIPLSVMYLMVMRYYIATSRQLKR-LESITRSPIYSHLSESIQGS 1202
Query: 299 KTIQAYCGEKKEIHRYA--DEVRKVFHVGLKEA-LTSGAFFGVT-GFVGN-VALLALLLT 353
TI+AY + R+ E + HV + + + V F+GN + L + L
Sbjct: 1203 ATIRAY----HLVDRFCKLSETKVDSHVQCRYLNYVANRWLSVRLEFIGNCIVLFSALFA 1258
Query: 354 GTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIH 413
+ T T G + + YA+ +L + RV E + +
Sbjct: 1259 ALTRTTT---TSGVIGLSVSYALNITTVLNFAVRQITKLETNIVSVERVKEYAETETEAE 1315
Query: 414 --PTIGKDPVTLENKSIHFNHVKFSYPTRPQ---HHIFEDLNFTVRPGEHVCIVGPSGGG 468
GK+P +N V +Y R + + + + LN ++P E V IVG +G G
Sbjct: 1316 WKSEPGKEPP--QNWPSEGRIVMNNYSARYRPGLNLVVKQLNVEIKPHEKVGIVGRTGAG 1373
Query: 469 KSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAV 528
KS+V L R + G+I + N+ + L R L ++ Q+P+LFSGT+ N+
Sbjct: 1374 KSSVTLSLFRIIEAAEGQIVVDGINLAEIGLHDLRSNLTIIPQDPVLFSGTLRFNLD--- 1430
Query: 529 PQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDP 588
P +D I + + AN +F + L + G +S GQ+Q + LARA L
Sbjct: 1431 PFNHYSDGD-IWKTLEMANLKEFATAHNEQLNYIITEGGDNISVGQRQLVCLARALLRKT 1489
Query: 589 SILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVA 648
+LILDEAT+A+D ++ ++ +++++ A T ++IAHR++TI R+IVLN G V
Sbjct: 1490 RVLILDEATAAVDVSTDALIQKTIREEFANA-TVLTIAHRLNTIMDYDRIIVLN-DGKVG 1547
Query: 649 ETGSFDKLIAIPDSSLNKLLSK 670
E S L++ +S + +
Sbjct: 1548 EFDSPANLLSNRNSEFYSMAKR 1569
Score = 84.7 bits (208), Expect = 4e-16
Identities = 65/212 (30%), Positives = 104/212 (48%), Gaps = 20/212 (9%)
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLG 507
+++F+V G+ V IVG G GKS++ L+ + SG I + L
Sbjct: 680 NISFSVNRGQLVTIVGRVGAGKSSMLQALMGEMEKLSGSISMHGR-------------LC 726
Query: 508 VVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRG 567
V Q+P + + T+ NIT+ DE SR + + L P G T +G +G
Sbjct: 727 YVPQQPWMQNNTLRQNITFGKQF----DEYFYSRVLDACALYRDLQILPLGDNTEIGEKG 782
Query: 568 TQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSL--QQRSARGKTTISI 625
LSGGQK RI+LARA + I +LD+ SA+D+ + S+ + R KT I +
Sbjct: 783 INLSGGQKARISLARAVYQNHDIYLLDDPMSAVDAHVGSQLFGSVIGPEGMLRNKTRILV 842
Query: 626 AHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ +S ++ S +IV+N G + +G +D L+
Sbjct: 843 TNELSFLEKSDLIIVMN-EGKIEYSGKYDDLM 873
>Hs20539468 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 131
Score = 115 bits (289), Expect = 2e-25
Identities = 64/127 (50%), Positives = 87/127 (68%), Gaps = 3/127 (2%)
Query: 492 DNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKF 551
++IR N+R YR +GVV QEP+LF TI +NI Y ++ V DE + RA +AN F
Sbjct: 5 NDIRALNVRHYRDHIGVVSQEPVLFGTTISNNIKYG--RDDVTDE-EMERAAREANAYDF 61
Query: 552 LANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQS 611
+ FP+ T VG +G Q+SGGQKQRIA+ARA + +P ILILDEATSALDS+S+ V +
Sbjct: 62 IMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAA 121
Query: 612 LQQRSAR 618
L++ + R
Sbjct: 122 LEKDTPR 128
>At2g47800 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1516
Score = 115 bits (289), Expect = 2e-25
Identities = 119/487 (24%), Positives = 217/487 (44%), Gaps = 35/487 (7%)
Query: 189 MKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFIS 248
+ + L +F D G ++SR S+D V + L V+ + + ++
Sbjct: 1033 LNSILHAPMSFFDTTPSGRILSRASTDQTNVDILIPFMLG----LVVSMYTTLLSIFIVT 1088
Query: 249 WKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVS-----EEQLSATKTIQA 303
+ PLG + + Y SR+L T + +TK E ++ TI++
Sbjct: 1089 CQYAWPTAFFVIPLGWLNIWYRNYYLASSREL-TRMDSITKAPIIHHFSESIAGVMTIRS 1147
Query: 304 YCGEK----KEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIK 359
+ ++ + + R D +R FH V +V ++ L ++L +++I+
Sbjct: 1148 FRKQELFRQENVKRVNDNLRMDFHNNGSNEWLGFRLELVGSWVLCISALFMVLLPSNVIR 1207
Query: 360 ---TGL-MTVG-DLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHP 414
GL ++ G L+S + +A+ + + + +RK + P
Sbjct: 1208 PENVGLSLSYGLSLNSVLFFAIYMSCFVENKMVSVERIKQFTDIPSE--SEWERKETLPP 1265
Query: 415 TIGKDPVTLENKSIHFNHVKFSY-PTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVA 473
+ + ++H +K Y P P + + + ++ GE V +VG +G GKST+
Sbjct: 1266 SNWPF-----HGNVHLEDLKVRYRPNTPL--VLKGITLDIKGGEKVGVVGRTGSGKSTLI 1318
Query: 474 SLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELV 533
+L R + G+I + +I L R G++ QEP+LF GT+ NI P E
Sbjct: 1319 QVLFRLVEPSGGKIIIDGIDISTLGLHDLRSRFGIIPQEPVLFEGTVRSNID---PTEQY 1375
Query: 534 NDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILIL 593
+DE I +++ + +A P+ L + V G S GQ+Q + L R L +L L
Sbjct: 1376 SDE-EIWKSLERCQLKDVVATKPEKLDSLVVDNGENWSVGQRQLLCLGRVMLKRSRLLFL 1434
Query: 594 DEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSF 653
DEAT+++DSQ++ V+ + +++ A T ISIAHR+ T+ RV+V++ G E S
Sbjct: 1435 DEATASVDSQTDAVIQKIIREDFA-SCTIISIAHRIPTVMDGDRVLVIDA-GKAKEFDSP 1492
Query: 654 DKLIAIP 660
+L+ P
Sbjct: 1493 ARLLERP 1499
Score = 106 bits (265), Expect = 1e-22
Identities = 66/234 (28%), Positives = 116/234 (49%), Gaps = 18/234 (7%)
Query: 425 NKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGS 484
N ++ FS+ D+NF V+ GE IVG G GKS++ + +L S
Sbjct: 638 NTAVEVRDGSFSWDDEDNEPALSDINFKVKKGELTAIVGTVGSGKSSLLASVLGEMHRIS 697
Query: 485 GEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIG 544
G++++ G V Q + +GT+ DNI + +P + ++ +
Sbjct: 698 GQVRVCGST-------------GYVAQTSWIENGTVQDNILFGLPMV----REKYNKVLN 740
Query: 545 QANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQS 604
+ K L G +T +G RG LSGGQKQRI LARA + + +LD+ SA+D+ +
Sbjct: 741 VCSLEKDLQMMEFGDKTEIGERGINLSGGQKQRIQLARAVYQECDVYLLDDVFSAVDAHT 800
Query: 605 EEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
+ + + + +GKT + + H+V + H+ I++ R G + E+G +D+L++
Sbjct: 801 GSDIFKKCVRGALKGKTVLLVTHQVDFL-HNVDCILVMRDGKIVESGKYDELVS 853
>YHL035c [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1592
Score = 114 bits (285), Expect = 5e-25
Identities = 128/531 (24%), Positives = 228/531 (42%), Gaps = 82/531 (15%)
Query: 160 VVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIV 219
++ A+ + ++ ++G R ++ + L F D VG +++R S D
Sbjct: 1050 IIQAMLGGFKTMMTFLSGMRASRKIFNNLLDLVLHAQIRFFDVTPVGRIMNRFSKDI--- 1106
Query: 220 SKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQ 279
+ V Q L I + + F+ +T + +A + V+ GK SR+
Sbjct: 1107 -EGVDQELIPYLEVTIFCLIQCASIIFLITVITPRFLTVAVIVFVLYFFVGKWYLTASRE 1165
Query: 280 LQTSVGELTKVS-----EEQLSATKTIQAYCGEKKEIHRYADEV----RKVFH------- 323
L+ + +TK E L TI+A+ E++ I +++ R F+
Sbjct: 1166 LKR-LDSITKSPIFQHFSETLVGVCTIRAFGDERRFILENMNKIDQNNRAFFYLSVTVKW 1224
Query: 324 -------VGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAV 376
+G L SG+F + N+A + L G S+ L T G L +Y+
Sbjct: 1225 FSFRVDMIGAFIVLASGSFILL-----NIANIDSGLAGISLTYAILFTDGALWLVRLYST 1279
Query: 377 XXXXXXXXXXXXXXELMKGAGAAA----RVFELNDRKPLIHPTIGKD-PVTLENKSIHFN 431
++ R+ LN+ P+ KD + +EN S+ +
Sbjct: 1280 FEMNMNSVERLKEYSSIEQENYLGHDEGRILLLNE------PSWPKDGEIEIENLSLRYA 1333
Query: 432 HVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGN 491
P P + +++F V P + IVG +G GKST+ + L R + +G IK+
Sbjct: 1334 ------PNLPP--VIRNVSFKVDPQSKIGIVGRTGAGKSTIITALFRLLEPITGCIKIDG 1385
Query: 492 DNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANC--- 548
+I +L RR + ++ Q+P+LF+GTI N+ P + DE +I +A+ Q N
Sbjct: 1386 QDISKIDLVTLRRSITIIPQDPILFAGTIKSNVD---PYD-EYDEKKIFKALSQVNLISS 1441
Query: 549 -----------------TKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSIL 591
KFL L T + G LS G++Q + +AR+ L +P I+
Sbjct: 1442 HEFEEVLNSEERFNSTHNKFL-----NLHTEIAEGGLNLSQGERQLLFIARSLLREPKII 1496
Query: 592 ILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLN 642
+LDEATS++D S+ ++ Q + + T ++IAHR+ ++ R+IV++
Sbjct: 1497 LLDEATSSIDYDSDHLI-QGIIRSEFNKSTILTIAHRLRSVIDYDRIIVMD 1546
Score = 70.9 bits (172), Expect = 6e-12
Identities = 59/214 (27%), Positives = 99/214 (45%), Gaps = 12/214 (5%)
Query: 449 LNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGN-----DNIRDFNLRKYR 503
LN + G+ I+G +G GKS + LL ++ SG I + + D I D
Sbjct: 688 LNIKFQIGKLNLILGSTGSGKSALLLGLLGELNLISGSIIVPSLEPKHDLIPD--CEGLT 745
Query: 504 RLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTV 563
Q L + T+ +NI + + +E R ++ I + L P G T +
Sbjct: 746 NSFAYCSQSAWLLNDTVKNNIIF----DNFYNEDRYNKVIDACGLKRDLEILPAGDLTEI 801
Query: 564 GPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQS-LQQRSARGKTT 622
G +G LSGGQKQRI+LARA ++LD+ SA+DS + + ++ + + +T
Sbjct: 802 GEKGITLSGGQKQRISLARAVYSSAKHVLLDDCLSAVDSHTAVWIYENCITGPLMKNRTC 861
Query: 623 ISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
I + H VS ++ ++ +G V G+ +L
Sbjct: 862 ILVTHNVSLTLRNAHFAIVLENGKVKNQGTITEL 895
>SPAC9E9.12c [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1427
Score = 114 bits (285), Expect = 5e-25
Identities = 130/518 (25%), Positives = 222/518 (42%), Gaps = 56/518 (10%)
Query: 164 LANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSV 223
L ++ R + G + + L + + G +++R S D
Sbjct: 915 LMDLSRAITFAKGGRTASENIHDILSERVLYSPLHWFEKTAAGRILNRFSKDM-----YA 969
Query: 224 TQNLSDGTRAVIQGFVGFGMMSFISW-KLTCVMMLLAPPLGVMALV-------YGKRIRN 275
T NL A ++G + M I+ +T VM + P ++L+ Y K +
Sbjct: 970 TDNL---LWASLEGMLLCVMAILITMLNVTLVMPIFMVPAAFVSLLVYLHGYAYSKAQKQ 1026
Query: 276 LSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHR---YADEVRKVFHVGLKE---- 328
L+ + + + E L I+A+ EK H + D++ + ++
Sbjct: 1027 LTSLQSSRTSPVFTMLGETLGGITVIRAFKKEKIFEHENMAFIDDMIQPLYISFAINRWL 1086
Query: 329 ALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXX 388
A+ + G+ GF + L+ALL I GL+ + A+
Sbjct: 1087 AIRTDGISGLVGF--STGLIALLRQN---IPPGLVGFS-----LNSAIGFNISVLVFVRA 1136
Query: 389 XXELMKGAGAAARVFEL-------NDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRP 441
E++ R++E N+ L P + K+ TL + SI V +S
Sbjct: 1137 NNEILTYINNFRRLYEYMLLPSEKNESSCLTKP-MNKEWPTLGHVSIKNLTVSYSIG--- 1192
Query: 442 QHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRK 501
Q + ED+N + P E + IVG +G GKST+ LLR+ I SG +++ +I +L
Sbjct: 1193 QAAVLEDINLEILPKEKIAIVGRTGSGKSTMGLTLLRFTMIMSGAVEVDGIDINSLDLEV 1252
Query: 502 YRRLLGVVQQEPMLFSGTILDNITYAVPQELVND-------ETRISRAIGQANCTKFLAN 554
R+ + ++ Q+P+L SGT+ N+ P E D +T ++ QA+ L
Sbjct: 1253 LRQRISLIPQDPVLISGTVRSNLD---PFEEYGDGELNEILKTASCESLVQASNKNSLDA 1309
Query: 555 FPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQ 614
F L T V G S GQ+Q +ALARA + I+ILDE+T+++D ++ + Q L +
Sbjct: 1310 FAIHLDTPVDSGGVNFSSGQRQILALARALVRKSRIVILDESTASVDDTTDRRIQQML-R 1368
Query: 615 RSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGS 652
+ + T + IAHR+ TI +V+VL+ G E GS
Sbjct: 1369 AAFKHATVLCIAHRIKTIVDYDKVLVLD-SGKTVEFGS 1405
Score = 86.7 bits (213), Expect = 1e-16
Identities = 73/236 (30%), Positives = 108/236 (44%), Gaps = 19/236 (8%)
Query: 427 SIHFNHVKFSYPTRPQHHIFE--DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGS 484
S F + S+ P +F+ +LNFT+ + +VG +G GKST+A LL + S
Sbjct: 576 SFVFENTSLSWSPTPSTALFQLKNLNFTIPRNQFTLVVGSTGSGKSTLAMALLGELHVIS 635
Query: 485 GEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIG 544
G++ + + R + V Q L +GTI NI + P DE R + I
Sbjct: 636 GKMTTPSISQR----------IAYVPQAAWLRNGTIRSNILFGEPY----DEERYFQIIK 681
Query: 545 QANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALD-SQ 603
L + DG T + G+ LSGGQKQR++LARA + + I D+ SALD S
Sbjct: 682 ACCLDSDLNSMNDGDLTYIHSNGSSLSGGQKQRVSLARALYSNAEVYIFDDIFSALDVST 741
Query: 604 SEEVVAQSLQQRSARGKTTISIAHRVS-TIQHSSRVIVL-NRHGTVAETGSFDKLI 657
S ++ + KT I H VS + + VIVL N + S +L+
Sbjct: 742 SRKIYESCFLSTLLQHKTIILFTHNVSLCLPIAENVIVLKNSTAQLVSPDSIQELV 797
>7291275 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1283
Score = 113 bits (283), Expect = 9e-25
Identities = 72/226 (31%), Positives = 128/226 (55%), Gaps = 7/226 (3%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
I LNF +P E + IVG +G GKS++ L R + G I++ +I L R
Sbjct: 1034 ILRGLNFESQPMEKIGIVGRTGAGKSSIIQALFRLA-LNEGTIEIDGLDIGKLGLHDLRS 1092
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
+ ++ Q+P+LFSGT+ N+ P + +DE+ S A+ K +A+ GL +
Sbjct: 1093 RISIIPQDPVLFSGTLRFNLD---PFDEKSDESLWS-ALDDVKLKKHVASLEGGLSCRMQ 1148
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
G+ S GQ+Q + LARA L +L++DEAT+ +D++++ ++ +++Q + A T ++
Sbjct: 1149 DGGSNFSMGQRQLVCLARAILRQNRVLVMDEATANVDTETDILIQETIQTKFAE-CTVLT 1207
Query: 625 IAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
IAHR+ T+ + V+V++ G + E G+ KL+ D +L KL+++
Sbjct: 1208 IAHRLHTVMDNDSVLVMDA-GQIVEFGAPHKLLQRKDGALLKLVNQ 1252
Score = 96.7 bits (239), Expect = 1e-19
Identities = 76/257 (29%), Positives = 117/257 (44%), Gaps = 22/257 (8%)
Query: 404 ELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPT----RPQHHIFEDLNFTVRPGEHV 459
EL+ KP + V E K + F V S+ +P+ E ++F + G+ V
Sbjct: 375 ELDAEKPKPAQSGRLHCVQSETKCLSFRKVSASWDKPSIKQPRKPHIEGISFHINAGQFV 434
Query: 460 CIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGT 519
IVG G GKST+ +L GEI+L + Y Q+P +F G+
Sbjct: 435 GIVGNVGSGKSTLLHAIL-------GEIELMQGRVEVHGRISY------AAQQPWVFQGS 481
Query: 520 ILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIA 579
I +NI + E E R + + L P G T VG RG LSGGQK RIA
Sbjct: 482 IRENILFVEQYE----EKRYRAVVHACQLDRDLELLPRGDATVVGERGISLSGGQKARIA 537
Query: 580 LARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVI 639
LARA I + D+ +A+D+Q +++ R GK I + H V ++ +++
Sbjct: 538 LARAVYRQADIYLFDDPLAAVDAQVGKLLMDKCFHRLLDGKMRILVTHHVQLLKSVDQLL 597
Query: 640 VLNRHGTVAETGSFDKL 656
+L G + + GS+++L
Sbjct: 598 LL-EGGKLTQQGSYEEL 613
>At3g13090 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1314
Score = 113 bits (282), Expect = 1e-24
Identities = 125/537 (23%), Positives = 228/537 (42%), Gaps = 26/537 (4%)
Query: 143 IFGLTSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDH 202
+ G T Y L V + + R +++ +TG ++ L T+ +F D
Sbjct: 783 VSGFTLILVYVLLA---VASSFCILIRALLVAMTGFKMATELFTQMHLRIFRASMSFFDA 839
Query: 203 NRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPL 262
+G +++R S+D + + + A I G++ ++W++ V + +
Sbjct: 840 TPMGRILNRASTDQSVADLRLPGQFAYVAIAAINILGIIGVIVQVAWQVLIVFIPVVAAC 899
Query: 263 GVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKK---EIHRYADEVR 319
Y R L+R S + E LS TI+++ E + +I R +D
Sbjct: 900 AWYRQYYISAARELARLAGISRSPVVHHFSETLSGITTIRSFDQEPRFRGDIMRLSDCYS 959
Query: 320 KV-FH-VGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVX 377
++ FH G E L ++ F +L+ L+ +I L + + YA+
Sbjct: 960 RLKFHSTGAMEWLCFRLEL-LSTFAFASSLVILVSAPEGVINPSLAGLA-----ITYALN 1013
Query: 378 XXXXXXXXXXXXXELMKGAGAAARVFELND---RKPLIHPTIGKDPVTLENKSIHFNHVK 434
+L + R+ + + PL+ T + I +++
Sbjct: 1014 LNTLQATLIWTLCDLENKMISVERMLQYTNIPSEPPLVIETTRPEKSWPSRGEITICNLQ 1073
Query: 435 FSY-PTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDN 493
Y P P + L T G IVG +G GKST+ L R + +GEI++ N
Sbjct: 1074 VRYGPHLPM--VLHGLTCTFPGGLKTGIVGRTGCGKSTLIQTLFRIVEPAAGEIRIDGIN 1131
Query: 494 IRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLA 553
I L R L ++ Q+P +F GTI N+ P E D+ +I A+ +
Sbjct: 1132 ILSIGLHDLRSRLSIIPQDPTMFEGTIRSNLD---PLEEYTDD-QIWEALDNCQLGDEVR 1187
Query: 554 NFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQ 613
L + V G S GQ+Q + L R L +L+LDEAT+++D+ ++ ++ ++L+
Sbjct: 1188 KKELKLDSPVSENGQNWSVGQRQLVCLGRVLLKRSKLLVLDEATASIDTATDNLIQETLR 1247
Query: 614 QRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
A T I+IAHR+S++ S V++L++ G + E S +L+ S +KL+++
Sbjct: 1248 HHFA-DCTVITIAHRISSVIDSDMVLLLDQ-GLIKEHDSPARLLEDRSSLFSKLVAE 1302
Score = 97.8 bits (242), Expect = 5e-20
Identities = 66/242 (27%), Positives = 114/242 (46%), Gaps = 18/242 (7%)
Query: 416 IGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASL 475
+G+ P ++ ++ FS+ D+NF V G +V I G G GKS++ S
Sbjct: 437 VGRLPSGSSEMAVEISNGTFSWDDSSPIPTLRDMNFKVSQGMNVAICGTVGSGKSSLLSS 496
Query: 476 LLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVND 535
+L GE+ + N++ + Y + Q P + SG + +NI + P E
Sbjct: 497 IL-------GEVPKISGNLKVCGRKAY------IAQSPWIQSGKVEENILFGKPME---- 539
Query: 536 ETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDE 595
R + + K L P QT +G RG LSGGQKQRI +ARA D I + D+
Sbjct: 540 REWYDRVLEACSLNKDLEILPFHDQTVIGERGINLSGGQKQRIQIARALYQDADIYLFDD 599
Query: 596 ATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDK 655
SA+D+ + + + + R KT I + H+V + + ++V+ + G + + G + +
Sbjct: 600 PFSAVDAHTGSHLFKEVLLGLLRHKTVIYVTHQVEFLPEADLILVM-KDGKITQAGKYHE 658
Query: 656 LI 657
++
Sbjct: 659 IL 660
>Hs6715561 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1503
Score = 112 bits (281), Expect = 1e-24
Identities = 86/251 (34%), Positives = 130/251 (51%), Gaps = 19/251 (7%)
Query: 414 PTIGKDPVTLENKSIHFNHVKFSYPTRPQHHI-FEDLNFTVRPGEHVCIVGPSGGGKSTV 472
PT P + I F Y RP+ + + ++F + GE V IVG +G GKS++
Sbjct: 1251 PTCAAQPPWPQGGQIEFRDFGLRY--RPELPLAVQGVSFKIHAGEKVGIVGRTGAGKSSL 1308
Query: 473 ASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQEL 532
AS LLR + G I + I L R + ++ Q+P+LF G++ N+ + QE
Sbjct: 1309 ASGLLRLQEAAEGGIWIDGVPIAHVGLHTLRSRISIIPQDPILFPGSLRMNLD--LLQE- 1365
Query: 533 VNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILI 592
+ + I A+ +A+ P LQ RG LS GQKQ + LARA L ILI
Sbjct: 1366 -HSDEAIWAALETVQLKALVASLPGQLQYKCADRGEDLSVGQKQLLCLARALLRKTQILI 1424
Query: 593 LDEATSALDSQSEEVVAQSLQQRSARGK-----TTISIAHRVSTIQHSSRVIVLNRHGTV 647
LDEAT+A+D +E LQ ++ G T + IAHR+ ++ +RV+V+++ G V
Sbjct: 1425 LDEATAAVDPGTE------LQMQAMLGSWFAQCTVLLIAHRLRSVMDCARVLVMDK-GQV 1477
Query: 648 AETGSFDKLIA 658
AE+GS +L+A
Sbjct: 1478 AESGSPAQLLA 1488
Score = 89.0 bits (219), Expect = 2e-17
Identities = 71/243 (29%), Positives = 120/243 (49%), Gaps = 28/243 (11%)
Query: 417 GKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL 476
GKD +T IH +S + P H +N TV G + +VGP G GKS++ S L
Sbjct: 625 GKDCIT-----IHSATFAWSQESPPCLH---RINLTVPQGCLLAVVGPVGAGKSSLLSAL 676
Query: 477 LRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDE 536
L G + + + V QE + + ++++N+ + QEL D
Sbjct: 677 LGELSKVEGFVSIEG-------------AVAYVPQEAWVQNTSVVENVCFG--QEL--DP 719
Query: 537 TRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEA 596
+ R + + +FP+G+ T++G +G LSGGQKQR++LARA ++ +LD+
Sbjct: 720 PWLERVLEACALQPDVDSFPEGIHTSIGEQGMNLSGGQKQRLSLARAVYRKAAVYLLDDP 779
Query: 597 TSALDSQ-SEEVVAQSLQQRS-ARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFD 654
+ALD+ + V Q + +G T I + H + + + +IVL +G +AE GS+
Sbjct: 780 LAALDAHVGQHVFNQVIGPGGLLQGTTRILVTHALHILPQADWIIVL-ANGAIAEMGSYQ 838
Query: 655 KLI 657
+L+
Sbjct: 839 ELL 841
>At3g62700 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1539
Score = 112 bits (281), Expect = 1e-24
Identities = 72/217 (33%), Positives = 115/217 (52%), Gaps = 8/217 (3%)
Query: 427 SIHFNHVKFSY-PTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSG 485
+I VK Y P P + + L ++ GE + +VG +G GKST+ +L R + G
Sbjct: 1296 NIRLEDVKVRYRPNTPL--VLKGLTIDIKGGEKIGVVGRTGSGKSTLIQVLFRLVEPSGG 1353
Query: 486 EIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQ 545
+I + +I L R G++ QEP+LF GT+ NI P E +DE I +++ +
Sbjct: 1354 KIIIDGIDICTLGLHDLRSRFGIIPQEPVLFEGTVRSNID---PTEKYSDE-EIWKSLER 1409
Query: 546 ANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSE 605
+A+ P+ L + V G S GQ+Q + L R L IL LDEAT+++DSQ++
Sbjct: 1410 CQLKDVVASKPEKLDSLVADNGENWSVGQRQLLCLGRVMLKRSRILFLDEATASVDSQTD 1469
Query: 606 EVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLN 642
++ Q + + T ISIAHR+ T+ RV+V++
Sbjct: 1470 AMI-QKIIREDFSDCTIISIAHRIPTVMDCDRVLVID 1505
Score = 105 bits (262), Expect = 2e-22
Identities = 66/234 (28%), Positives = 118/234 (50%), Gaps = 18/234 (7%)
Query: 425 NKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGS 484
N ++ FS+ E++NF V+ GE IVG G GKS++ + +L
Sbjct: 636 NVAVEIKDGSFSWDDEDDEPAIENINFEVKKGELAAIVGTVGSGKSSLLASVL------- 688
Query: 485 GEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIG 544
GE+ + +R Y V Q + +GT+ DNI + +P + ++ + +
Sbjct: 689 GEMHKLSGKVRVCGTTAY------VAQTSWIQNGTVQDNILFGLPM----NRSKYNEVLK 738
Query: 545 QANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQS 604
K + G QT +G RG LSGGQKQRI LARA + + +LD+ SA+D+ +
Sbjct: 739 VCCLEKDMQIMEFGDQTEIGERGINLSGGQKQRIQLARAVYQESDVYLLDDVFSAVDAHT 798
Query: 605 EEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
+ + + + +GKT + + H+V + + R++V+ R G + ++G +D+L++
Sbjct: 799 GSDIFKKCVRGALKGKTILLVTHQVDFLHNVDRILVM-RDGMIVQSGKYDELVS 851
>At3g60970 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1037
Score = 112 bits (281), Expect = 1e-24
Identities = 124/533 (23%), Positives = 219/533 (40%), Gaps = 48/533 (9%)
Query: 155 LGGVFVVGALANVG-------RIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGD 207
+G + +V AL G R +++ + G +R + + ++ D G
Sbjct: 520 MGRILLVYALLAAGSSLCVLARTILVAIGGLSTAETFFSRMLCSIFRAPMSYFDSTPTGR 579
Query: 208 LISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMAL 267
+++R S+D ++ + L ++IQ +MS ++W+
Sbjct: 580 ILNRASTDQSVLDLEMAVKLGWCAFSIIQIVGTIFVMSQVAWQ----------------R 623
Query: 268 VYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHR----YADEVRKVFH 323
Y R LSR + E L+ TI+A+ + I R FH
Sbjct: 624 YYTPTERELSRMSGVERAPILHHFAESLAGATTIRAFDQRDRFISSNLVLIDSHSRPWFH 683
Query: 324 VGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXX 383
V S ++ FV +L+ L+ +I + +G + Y +
Sbjct: 684 VASAMEWLSFRLNLLSHFVFAFSLVLLVTLPEGVINPSIAGLG-----VTYGLSLNVLQA 738
Query: 384 XXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLEN----KSIHFNHVKFSYPT 439
+ R+ + + + P P + D L+N SI F ++ Y
Sbjct: 739 TVIWNICNAENKMISVERILQ-HSKIPSEAPLVIDDQRPLDNWPNVGSIVFRDLQVRY-- 795
Query: 440 RPQHH--IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDF 497
+H + +++ G+ + +VG +G GKST+ L R + G I + N +I
Sbjct: 796 -AEHFPAVLKNITCAFPGGKKIGVVGRTGSGKSTLIQALFRIVEPSHGTIVIDNVDITKI 854
Query: 498 NLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPD 557
L R LG++ Q+ LF GTI N+ P D I A+ + + +
Sbjct: 855 GLHDLRSRLGIIPQDNALFDGTIRLNLD---PLAQYTDR-EIWEALDKCQLGDVIRAKDE 910
Query: 558 GLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSA 617
L TV G S GQ+Q + L R L +IL+LDEAT+++DS ++ V+ Q + +
Sbjct: 911 KLDATVVENGENWSVGQRQLVCLGRVLLKKSNILVLDEATASVDSATDGVI-QKIINQEF 969
Query: 618 RGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
+ +T ++IAHR+ T+ S V+VL+ G +AE S KL+ DS +KL+ +
Sbjct: 970 KDRTVVTIAHRIHTVIESDLVLVLS-DGRIAEFDSPAKLLQREDSFFSKLIKE 1021
Score = 97.1 bits (240), Expect = 8e-20
Identities = 65/231 (28%), Positives = 110/231 (47%), Gaps = 18/231 (7%)
Query: 427 SIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGE 486
S+ + FS+ +D+ V+ G V I G G GKS++ S +L GE
Sbjct: 213 SVEIENGAFSWEPESSRPTLDDIELKVKSGMKVAICGAVGSGKSSLPSSIL-------GE 265
Query: 487 IKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQA 546
I+ +R + Y V Q P + SGTI DNI + + + + R +
Sbjct: 266 IQKLKGTVRVSGKQAY------VPQSPWILSGTIRDNILFGS----IYESEKYERTVKAC 315
Query: 547 NCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEE 606
K F +G T +G RG +SGGQKQRI +ARA + I +LD+ SA+D+ +
Sbjct: 316 ALIKDFELFSNGDLTEIGERGINMSGGQKQRIQIARAVYQNADIYLLDDPFSAVDAHTGR 375
Query: 607 VVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ + + KT + + H+V + + ++V+ ++G V + G F++L+
Sbjct: 376 ELFEDCLMGILKDKTVLYVTHQVEFLPAADLILVM-QNGRVMQAGKFEELL 425
>At1g04120 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1514
Score = 112 bits (279), Expect = 3e-24
Identities = 124/520 (23%), Positives = 224/520 (42%), Gaps = 41/520 (7%)
Query: 169 RIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLS 228
R ++ G +L +++ +F D G +++R+S D +V + L
Sbjct: 1007 RAALVATFGLAAAQKLFLNMLRSVFRAPMSFFDSTPAGRILNRVSIDQSVVDLDIPFRLG 1066
Query: 229 DGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELT 288
IQ +M+ ++W++ +++ +A M Y R L R + +
Sbjct: 1067 GFASTTIQLCGIVAVMTNVTWQVFLLVVPVAVACFWMQKYYMASSRELVRIVSIQKSPII 1126
Query: 289 KVSEEQLSATKTIQAYCGEKKEIHR-----------YADEVRKVFHVGLKEALTSGAFFG 337
+ E ++ TI+ + EK+ I R + + + + L+ L S F
Sbjct: 1127 HLFGESIAGAATIRGFGQEKRFIKRNLYLLDCFVRPFFCSIAAIEWLCLRMELLSTLVFA 1186
Query: 338 VTGFVGNVALLALLLTGT---SM----IKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXX 390
+ LL GT SM + GL G LS +++ +
Sbjct: 1187 FC-----MVLLVSFPHGTIDPSMAGLAVTYGLNLNGRLSRWIL-SFCKLENKIISIERIY 1240
Query: 391 ELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLN 450
+ + G A + E + R P P G T+E + + + + PT + ++
Sbjct: 1241 QYSQIVGEAPAIIE-DFRPPSSWPATG----TIELVDVKVRYAE-NLPT-----VLHGVS 1289
Query: 451 FTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQ 510
G+ + IVG +G GKST+ L R + +G+I + N +I L R LG++
Sbjct: 1290 CVFPGGKKIGIVGRTGSGKSTLIQALFRLIEPTAGKITIDNIDISQIGLHDLRSRLGIIP 1349
Query: 511 QEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQL 570
Q+P LF GTI N+ P E +D+ +I A+ ++ + L + V G
Sbjct: 1350 QDPTLFEGTIRANLD---PLEEHSDD-KIWEALDKSQLGDVVRGKDLKLDSPVLENGDNW 1405
Query: 571 SGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVS 630
S GQ+Q ++L RA L IL+LDEAT+++D+ ++ ++ Q + + T +IAHR+
Sbjct: 1406 SVGQRQLVSLGRALLKQAKILVLDEATASVDTATDNLI-QKIIRTEFEDCTVCTIAHRIP 1464
Query: 631 TIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLSK 670
T+ S V+VL+ G VAE + +L+ S KL+++
Sbjct: 1465 TVIDSDLVLVLS-DGRVAEFDTPARLLEDKSSMFLKLVTE 1503
Score = 98.6 bits (244), Expect = 3e-20
Identities = 94/408 (23%), Positives = 170/408 (41%), Gaps = 21/408 (5%)
Query: 251 LTCVMMLLAPPLGVMALVYGKRIR-NLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKK 309
+ V L+A + ++ + +++ + +L T+ E + + E L + ++ E +
Sbjct: 446 IAAVATLVATIISILVTIPLAKVQEDYQDKLMTAKDERMRKTSECLRNMRVLKLQAWEDR 505
Query: 310 EIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLS 369
R +E+R+ + L++AL S AF + + + A+ + + T L G LS
Sbjct: 506 YRVRL-EEMREEEYGWLRKALYSQAFVTFIFWSSPIFVAAVTFATSIFLGTQLTAGGVLS 564
Query: 370 SFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKSIH 429
+ + + + + + R+ + L P L N +I
Sbjct: 565 ALATFRILQEPLRNFPDLVSM-MAQTKVSLDRISGFLQEEELQEDATVVIPRGLSNIAIE 623
Query: 430 FNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKL 489
F + + V G V + G G GKS+ S +L SGE+++
Sbjct: 624 IKDGVFCWDPFSSRPTLSGIQMKVEKGMRVAVCGTVGSGKSSFISCILGEIPKISGEVRI 683
Query: 490 GNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCT 549
G V Q + SG I +NI + P E +T+ I +
Sbjct: 684 CGTT-------------GYVSQSAWIQSGNIEENILFGSPME----KTKYKNVIQACSLK 726
Query: 550 KFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVA 609
K + F G QT +G RG LSGGQKQR+ LARA D I +LD+ SALD+ + +
Sbjct: 727 KDIELFSHGDQTIIGERGINLSGGQKQRVQLARALYQDADIYLLDDPFSALDAHTGSDLF 786
Query: 610 QSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ + KT + + H+V + + ++VL + G + ++G +D L+
Sbjct: 787 RDYILSALAEKTVVFVTHQVEFLPAADLILVL-KEGRIIQSGKYDDLL 833
>CE03119 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1398
Score = 111 bits (277), Expect = 4e-24
Identities = 110/499 (22%), Positives = 212/499 (42%), Gaps = 41/499 (8%)
Query: 170 IVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSD 229
+V+L + G L + L ++ D +G +I+RL+ D +V LS
Sbjct: 900 LVLLLIGGVAASKNLHKPLLHNVLRNPLSYFDITPIGRIINRLAKDMEVVDL----RLSS 955
Query: 230 GTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTK 289
R ++ + ++ +S+ + ++ P + V I++ +RQLQ + LT+
Sbjct: 956 SFRFLVMALINMTVL-IVSYTTPLFIAIIIPVFIIYFFVLKYSIKS-TRQLQR-IASLTR 1012
Query: 290 VS-----EEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGN 344
E L T++A+ + + R + + + + +GN
Sbjct: 1013 SPIFSNFSETLQGISTVRAFQWSDEFVRRNDEHLNTHVKCSYYSQMANRWLSIRLELLGN 1072
Query: 345 VALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFE 404
+ + + + ++G+ T G L + Y++ E+ + R+ E
Sbjct: 1073 IVIFSAAILAIIGKESGI-TAGMLGLSVSYSLNITFMLNMFVRQINEVETNVVSVERIDE 1131
Query: 405 L------------NDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFT 452
N+ P PT G V +E+ S + + + ++
Sbjct: 1132 YSKTKSEAEWRLDNNNLPSNWPTGGA--VNIEDYSCRYRD--------ELDLVLKQISLN 1181
Query: 453 VRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQE 512
+ PG+ V + G +G GKS++A L R + G I + L R L ++ QE
Sbjct: 1182 ILPGQKVGVCGRTGAGKSSLALALFRIVEAADGNISIDQTITSHIGLHDLREKLTIIPQE 1241
Query: 513 PMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSG 572
+LF+ T+ NI P+ D+ ++ A+ +N + P L++ V G S
Sbjct: 1242 NVLFANTLRFNID---PKGQFTDQ-QLWLALENSNLKAHVELLPHKLESPVAEGGENFSV 1297
Query: 573 GQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTI 632
GQ+Q + L RA L +L+LDEAT+ +D++++ +V +++++ A T I+IAHR+ TI
Sbjct: 1298 GQRQLLCLTRALLRKSKVLVLDEATAGIDNRTDTMVQATIREKFA-DSTIITIAHRLHTI 1356
Query: 633 QHSSRVIVLNRHGTVAETG 651
R+IV++ G + E G
Sbjct: 1357 IDYDRIIVMDA-GRIVEDG 1374
Score = 66.2 bits (160), Expect = 2e-10
Identities = 59/199 (29%), Positives = 90/199 (44%), Gaps = 19/199 (9%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
I D+ F E V +VG G GKS SLLL +G E G +R
Sbjct: 570 ILSDIEFLAGSKELVTVVGSVGSGKS---SLLLAA--LGEMEKVCGYVGVRGS------- 617
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
+ + Q+P + + ++ N+ + Q +ND + I + L PDG T +G
Sbjct: 618 -VAYLSQQPWILNQSLKKNV---LMQADLND-VLYKKVIESCALKEDLKQLPDGDDTEIG 672
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQ-SEEVVAQSLQQRSARGKTT- 622
+G LSGGQK RIALARA + LD+ SA+D+ + + + TT
Sbjct: 673 EKGINLSGGQKARIALARAVYQSKDVYFLDDPLSAVDAHVGKHIFDNVIGPNGMLSHTTR 732
Query: 623 ISIAHRVSTIQHSSRVIVL 641
I + + S +Q S ++IV+
Sbjct: 733 ILVTNCTSFLQESGKIIVM 751
>Hs15100172 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1359
Score = 110 bits (275), Expect = 7e-24
Identities = 71/225 (31%), Positives = 125/225 (55%), Gaps = 6/225 (2%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+ + LN ++ G+ V IVG +G GKS++ L R + SG I + +I +L R
Sbjct: 1136 VLDSLNLNIQSGQTVGIVGRTGSGKSSLGMALFRLVEPASGTIFIDEVDICILSLEDLRT 1195
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
L V+ Q+P+LF GT+ N+ P E DE + + + + + P+ LQ V
Sbjct: 1196 KLTVIPQDPVLFVGTVRYNLD---PFESHTDE-MLWQVLERTFMRDTIMKLPEKLQAEVT 1251
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
G S G++Q + +ARA L + I++LDEAT+++DS+++ +V +++ + +G T ++
Sbjct: 1252 ENGENFSVGERQLLCVARALLRNSKIILLDEATASMDSKTDTLVQNTIKD-AFKGCTVLT 1310
Query: 625 IAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLS 669
IAHR++T+ + V+V+ +G V E + L PDS+ LL+
Sbjct: 1311 IAHRLNTVLNCDHVLVM-ENGKVIEFDKPEVLAEKPDSAFAMLLA 1354
Score = 98.6 bits (244), Expect = 3e-20
Identities = 62/213 (29%), Positives = 104/213 (48%), Gaps = 18/213 (8%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+ ++F VR G+ + I G G GKS++ + LL + G + +
Sbjct: 495 VLHSISFVVRKGKILGICGNVGSGKSSLLAALLGQMQLQKGVVAVNGT------------ 542
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
L V Q+ +F G + +NI + D R + K L+N P G T +G
Sbjct: 543 -LAYVSQQAWIFHGNVRENILFGEKY----DHQRYQHTVRVCGLQKDLSNLPYGDLTEIG 597
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
RG LSGGQ+QRI+LARA D + +LD+ SA+D+ + V + +++ RGKT +
Sbjct: 598 ERGLNLSGGQRQRISLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKKTLRGKTVVL 657
Query: 625 IAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ H++ ++ VI+L G + E G+ +L+
Sbjct: 658 VTHQLQFLESCDEVILL-EDGEICEKGTHKELM 689
>At3g59140 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1389
Score = 110 bits (274), Expect = 1e-23
Identities = 107/500 (21%), Positives = 212/500 (42%), Gaps = 27/500 (5%)
Query: 182 ARLRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGF 241
A L ++ + + +F D +G ++SR+SSD IV V L + +
Sbjct: 895 ASLFSQLLNSLFRAPMSFYDSTPLGRILSRVSSDLSIVDLDVPFGLIFVVASSVNTGCSL 954
Query: 242 GMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTI 301
G+++ ++W++ V + + + Y + + L R T+ + E ++ TI
Sbjct: 955 GVLAIVTWQVLFVSVPMVYLAFRLQKYYFQTAKELMRINGTTRSYVANHLAESVAGAITI 1014
Query: 302 QAYCGE----KKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSM 357
+A+ E KK + FH V+ V ++L T
Sbjct: 1015 RAFDEEERFFKKSLTLIDTNASPFFHSFAANEWLIQRLETVSAIVLASTAFCMILLPTGT 1074
Query: 358 IKTGLMTVG-----DLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELND--RKP 410
+G + + L+ ++Y+V L + E+ + R P
Sbjct: 1075 FSSGFIGMALSYGLSLNMGLVYSVQNQCYLANWIISVERLNQYTHLTPEAPEVIEETRPP 1134
Query: 411 LIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKS 470
+ P G+ V + + I + R + + ++ T G + IVG +G GK+
Sbjct: 1135 VNWPVTGR--VEISDLQIRYR--------RESPLVLKGISCTFEGGHKIGIVGRTGSGKT 1184
Query: 471 TVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQ 530
T+ S L R + G+I + +I + R G++ Q+P LF+GT+ N+
Sbjct: 1185 TLISALFRLVEPVGGKIVVDGVDISKIGVHDLRSRFGIIPQDPTLFNGTVRFNLDPLCQ- 1243
Query: 531 ELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSI 590
+ + I +G+ + + +GL + V G+ S GQ+Q L RA L +
Sbjct: 1244 ---HSDAEIWEVLGKCQLKEVVQEKENGLDSLVVEDGSNWSMGQRQLFCLGRAVLRRSRV 1300
Query: 591 LILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAET 650
L+LDEAT+++D+ ++ ++ +++++ A T I++AHR+ T+ + V+ ++ G + E
Sbjct: 1301 LVLDEATASIDNATDLILQKTIRREFA-DCTVITVAHRIPTVMDCTMVLSIS-DGRIVEY 1358
Query: 651 GSFDKLIAIPDSSLNKLLSK 670
KL+ +S KL+ +
Sbjct: 1359 DEPMKLMKDENSLFGKLVKE 1378
Score = 99.0 bits (245), Expect = 2e-20
Identities = 67/211 (31%), Positives = 104/211 (48%), Gaps = 18/211 (8%)
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLG 507
+++ V+ GE V + G G GKST+ + +L SG I + +
Sbjct: 558 NVSLEVKFGEKVAVCGEVGSGKSTLLAAILGETPCVSGTID-------------FYGTIA 604
Query: 508 VVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRG 567
V Q + +GTI DNI + V DE R I +++ K L PDG QT +G RG
Sbjct: 605 YVSQTAWIQTGTIRDNILFGG----VMDEHRYRETIQKSSLDKDLELLPDGDQTEIGERG 660
Query: 568 TQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAH 627
LSGGQKQRI LARA D I +LD+ SA+D+ + + Q + GK + + H
Sbjct: 661 VNLSGGQKQRIQLARALYQDADIYLLDDPFSAVDAHTASSLFQEYVMDALAGKAVLLVTH 720
Query: 628 RVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
+V + V++++ G + E ++ +L+A
Sbjct: 721 QVDFLPAFDSVLLMS-DGEITEADTYQELLA 750
>Hs14211905 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1382
Score = 109 bits (272), Expect = 2e-23
Identities = 71/225 (31%), Positives = 126/225 (55%), Gaps = 6/225 (2%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+ +N T+R E V IVG +G GKS++ L R + +G I + +I L R
Sbjct: 1157 VLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRILIDGVDICSIGLEDLRS 1216
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
L V+ Q+P+L SGTI N+ P + D+ +I A+ + TK ++ FP L T V
Sbjct: 1217 KLSVIPQDPVLLSGTIRFNLD---PFDRHTDQ-QIWDALERTFLTKAISKFPKKLHTDVV 1272
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
G S G++Q + +ARA L + I+++DEAT+++D +++ ++ +++++ + +G T +
Sbjct: 1273 ENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTIRE-AFQGCTVLV 1331
Query: 625 IAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLS 669
IAHRV+T+ + R++V+ +G V E + L P S L++
Sbjct: 1332 IAHRVTTVLNCDRILVMG-NGKVVEFDRPEVLRKKPGSLFAALMA 1375
Score = 93.6 bits (231), Expect = 9e-19
Identities = 121/527 (22%), Positives = 208/527 (38%), Gaps = 75/527 (14%)
Query: 175 VTGERLVARLRTRTMKAALEQDATFLD--HNRVGDLISRLSSDAGIVSKSVTQNLSDGTR 232
+ +R R R A E+ F H G+ IS + D + + V G
Sbjct: 225 IINQRTAIRFRAAVSSFAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCY----GPL 280
Query: 233 AVIQ--GFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELT-K 289
+I V + S+ T + +L PL V+ R+ ++ + V + +
Sbjct: 281 VLITCASLVICSISSYFIIGYTAFIAILCYPLVFPLEVFMTRMAVKAQHHTSEVSDQRIR 340
Query: 290 VSEEQLSATKTIQAYCGEK---KEIHRYADEVRKVFH-VGLKEALTSGAFFGVTGFVGNV 345
V+ E L+ K I+ Y EK K I + RK+ GL ++LTS F +
Sbjct: 341 VTSEVLTCIKLIKMYTWEKPFAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPAVA--T 398
Query: 346 ALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFEL 405
A+ L+ T + T M L+S + + K A + F L
Sbjct: 399 AVWVLIHTSLKLKLTASMAFSMLASLNLLRLSVFFVPIAVKGLTNS--KSAVMRFKKFFL 456
Query: 406 NDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYP-----------------------TRPQ 442
+ P+ + +DP +K++ F S+ TRP+
Sbjct: 457 QE-SPVFYVQTLQDP----SKALVFEEATLSWQQTCPGIVNGALELERNGHASEGMTRPR 511
Query: 443 HHI------------FEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLG 490
+ +N V G + + G +G GKS++ S +L + G + +
Sbjct: 512 DALGPEEEGNSLGPELHKINLVVSKGMMLGVCGNTGSGKSSLLSAILEEMHLLEGSVGVQ 571
Query: 491 NDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTK 550
L V Q+ + SG I +NI D+ R + + + +
Sbjct: 572 GS-------------LAYVPQQAWIVSGNIRENILMGGAY----DKARYLQVLHCCSLNR 614
Query: 551 FLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQ 610
L P G T +G RG LSGGQKQRI+LARA D I +LD+ SA+D+ + + +
Sbjct: 615 DLELLPFGDMTEIGERGPNLSGGQKQRISLARAVYSDRQIYLLDDPLSAVDAHVGKHIFE 674
Query: 611 SLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+++ RGKT + + H++ ++ +VI+L +G + E G+ +L+
Sbjct: 675 ECIKKTLRGKTVVQVTHQLQYLEFCGQVILL-ENGKICENGTHSELM 720
>Hs22056689 [U] KOG0058 Peptide exporter ABC superfamily
Length = 473
Score = 108 bits (271), Expect = 2e-23
Identities = 65/152 (42%), Positives = 82/152 (53%), Gaps = 29/152 (19%)
Query: 461 IVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTI 520
+VGP G GKSTV SLLLR +D SG I L +IR N R +G
Sbjct: 268 LVGPGGSGKSTVLSLLLRLFDPASGTISLDGHDIRQLNPVWLRSKIG------------- 314
Query: 521 LDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIAL 580
T++ R AN + NFP G T VG +G LSGGQKQRIA+
Sbjct: 315 ----------------TQVQRVAEVANAVVLIRNFPQGFNTVVGEKGVLLSGGQKQRIAI 358
Query: 581 ARAFLLDPSILILDEATSALDSQSEEVVAQSL 612
ARA L +P IL+LDEATSALD+++E +V ++L
Sbjct: 359 ARALLKNPKILLLDEATSALDAENEYLVQEAL 390
Score = 97.4 bits (241), Expect = 6e-20
Identities = 53/153 (34%), Positives = 89/153 (57%), Gaps = 3/153 (1%)
Query: 149 TQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDL 208
T+ L GVF+ GA AN R+ +++ + +R+V RLRT + L Q+ F D G+L
Sbjct: 120 TRLCLGLSGVFLCGAAANAIRVYLMQTSRQRVVKRLRTSLFSSILGQEVAFSDKAGTGEL 179
Query: 209 ISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALV 268
I+RLSSD ++ +SVT+NLSDG RA + VG M +S ++ + P + ++ ++
Sbjct: 180 INRLSSDTALLGRSVTENLSDGLRAGARASVGIRTMFCVSPNRATFVVSVVPLVSIIDVI 239
Query: 269 YGKRIRNLSRQLQTSVGELTKVSEEQLSATKTI 301
YG+ +R L++ Q S+ + T +E+ S T +
Sbjct: 240 YGRYLRKLTKVTQDSLAQAT---QEERSVTALV 269
>Hs15149474 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1382
Score = 107 bits (267), Expect = 6e-23
Identities = 70/225 (31%), Positives = 125/225 (55%), Gaps = 6/225 (2%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+ +N T+R E V IVG +G GKS++ L R + +G I + +I L R
Sbjct: 1157 VLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRILIDGVDICSIGLEDLRS 1216
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
L V+ Q+P+L SGTI N+ P + D+ +I A+ + TK ++ FP L T V
Sbjct: 1217 KLSVIPQDPVLLSGTIRFNLD---PFDRHTDQ-QIWDALERTFLTKAISKFPKKLHTDVV 1272
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
G S G++Q + +ARA L + I+++DEAT+++D +++ ++ +++++ + +G T +
Sbjct: 1273 ENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTIRE-AFQGCTVLV 1331
Query: 625 IAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLS 669
IAHRV+T+ + ++V+ +G V E + L P S L++
Sbjct: 1332 IAHRVTTVLNCDHILVMG-NGKVVEFDRPEVLRKKPGSLFAALMA 1375
Score = 91.7 bits (226), Expect = 4e-18
Identities = 117/527 (22%), Positives = 209/527 (39%), Gaps = 75/527 (14%)
Query: 175 VTGERLVARLRTRTMKAALEQDATFLD--HNRVGDLISRLSSDAGIVSKSVTQN---LSD 229
+ +R R R A E+ F H G+ IS + D + + V L
Sbjct: 225 IINQRTAIRFRAAVSSFAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLIT 284
Query: 230 GTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTK 289
VI + ++ + ++ + + LL PL V + ++ + ++ + +
Sbjct: 285 CASLVICSISSYFIIGYTAF-IAILCYLLVFPLAVFMTRMAVKAQHHTSEVSD---QRIR 340
Query: 290 VSEEQLSATKTIQAYCGEK---KEIHRYADEVRKVFH-VGLKEALTSGAFFGVTGFVGNV 345
V+ E L+ K I+ Y EK K I + RK+ GL ++LTS F +
Sbjct: 341 VTSEVLTCIKLIKMYTWEKPFAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVA--T 398
Query: 346 ALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFEL 405
A+ L+ T + T M L+S + + K A + F L
Sbjct: 399 AVWVLIHTSLKLKLTASMAFSMLASLNLLRLSVFFVPIAVKGLTNS--KSAVMRFKKFFL 456
Query: 406 NDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYP-----------------------TRPQ 442
+ P+ + +DP +K++ F S+ TRP+
Sbjct: 457 QE-SPVFYVQTLQDP----SKALVFEEATLSWQQTCPGIVNGALELERNGHASEGMTRPR 511
Query: 443 HHI------------FEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLG 490
+ +N V G + + G +G GKS++ S +L + G + +
Sbjct: 512 DALGPEEEGNSLGPELHKINLVVSKGMMLGVCGNTGSGKSSLLSAILEEMHLLEGSVGVQ 571
Query: 491 NDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTK 550
L V Q+ + SG I +NI D+ R + + + +
Sbjct: 572 GS-------------LAYVPQQAWIVSGNIRENILMGGAY----DKARYLQVLHCCSLNR 614
Query: 551 FLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQ 610
L P G T +G RG LSGGQKQRI+LARA D I +LD+ SA+D+ + + +
Sbjct: 615 DLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDPLSAVDAHVGKHIFE 674
Query: 611 SLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+++ RGKT + + H++ ++ ++I+L +G + E G+ +L+
Sbjct: 675 ECIKKTLRGKTVVLVTHQLQYLEFCGQIILL-ENGKICENGTHSELM 720
>7297613 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 2250
Score = 106 bits (265), Expect = 1e-22
Identities = 77/244 (31%), Positives = 126/244 (51%), Gaps = 8/244 (3%)
Query: 428 IHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEI 487
IHF++V Y + Q+ + +L + G+ + I G +G GKS++ L G I
Sbjct: 2009 IHFDNVSLRYEGQKQN-VISNLTLKIPAGQRIGICGRTGSGKSSLGLSLFGVLQTTRGHI 2067
Query: 488 KLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQAN 547
+ + +I+ + R L ++ Q+ LF+ TI +N+ P D ++ + A
Sbjct: 2068 YIDDVDIQRIRPDELRTRLSIIPQDVHLFNATIRENLD---PHGYFQD-LQLWNCLELAQ 2123
Query: 548 CTKFL-ANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEE 606
+F+ + P GL T + G LS G +Q + LARA L L+LDEATS LDS +E
Sbjct: 2124 LKEFVNGHLPLGLDTVICDGGLNLSAGHRQLLCLARAILRGSVCLVLDEATSVLDSSTES 2183
Query: 607 VVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNK 666
+ ++ + RG+T I+IAHR++TI R+IVL++ G + E G+ +L + S
Sbjct: 2184 ALLKA-ADLAFRGRTIITIAHRLTTILDYDRLIVLDQ-GRIVEDGNPRELQQLEGSVFRG 2241
Query: 667 LLSK 670
LL K
Sbjct: 2242 LLEK 2245
Score = 63.2 bits (152), Expect = 1e-09
Identities = 54/206 (26%), Positives = 98/206 (47%), Gaps = 24/206 (11%)
Query: 453 VRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRL-LGVVQQ 511
V G+ +VG +G GK+++ S LL + +G N+ ++ + V Q
Sbjct: 889 VPKGKLTIVVGKNGSGKTSLLSALLMEMPLLAG------------NMFWHKTCTISYVSQ 936
Query: 512 EPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLS 571
+P L + TI +NI + R + + P G + +G RG +S
Sbjct: 937 QPWLLNDTIRENILFGESFR----PKRYDFVLEACALKPDIELMPRGDLSIIGERGINIS 992
Query: 572 GGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQ----SLQQRSARGKTTISIAH 627
GGQ+QRIA+ARA +++I+D+ ++LD++ E + Q + Q+S R T I +
Sbjct: 993 GGQRQRIAIARAIYSSANVVIMDDPLASLDNEVGEHIFQHCIREMLQKSNR--TFILVTQ 1050
Query: 628 RVSTIQHSSRVIVLNRHGTVAETGSF 653
++ I+ + +I + + G V GS+
Sbjct: 1051 QLHRIKEAEYLIAI-KDGRVEACGSY 1075
>ECU10g1230 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC superfamily
Length = 572
Score = 101 bits (251), Expect = 4e-21
Identities = 66/206 (32%), Positives = 109/206 (52%), Gaps = 6/206 (2%)
Query: 453 VRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQE 512
+R GE V I+G +G GKS++ + LLR+ + GE+ + +++ R L+ V Q
Sbjct: 368 IRKGEKVGIIGKNGCGKSSLINALLRFLEY-DGEVYVDGIDLKRIRKSSIRNLISFVPQS 426
Query: 513 PMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSG 572
LF+GT+L+NI Y+ + + + + + + G QT VG G LSG
Sbjct: 427 HHLFNGTVLENIAYSCNSV---EYDYVLKRCEHFDMHETFSKLGKGYQTLVGENGKFLSG 483
Query: 573 GQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTI 632
GQKQRI+ RA + D ++ LDE TS LD+ SE + + + ++ GKT + + H +
Sbjct: 484 GQKQRISFMRAMVKDSDVVALDEPTSNLDADSERRLVEMILKK-MDGKTVLLVVHDHDLL 542
Query: 633 QHSSRVIVLNRHGTVAETGSFDKLIA 658
+ +++ L + TV SFD+ IA
Sbjct: 543 KGFDKILGL-YNNTVRVYDSFDEFIA 567
>At1g30420 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1488
Score = 100 bits (250), Expect = 6e-21
Identities = 126/542 (23%), Positives = 220/542 (40%), Gaps = 59/542 (10%)
Query: 156 GGVFVVGALANVGRIVILKVTGERLVA-------RLRTRTMKAALEQDATFLDHNRVGDL 208
G VV AL G++ + L++ RL + + L F + N G +
Sbjct: 950 GFYIVVYALLGFGQVAVTFTNSFWLISSSLHAAKRLHDAMLNSILRAPMLFFETNPTGRV 1009
Query: 209 ISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALV 268
I+R S D G + ++V ++ + Q F ++ +S +M L +
Sbjct: 1010 INRFSKDIGDIDRNVANLMNMFMNQLWQLLSTFALIGIVSTISLWAIMPLLILFYATYIY 1069
Query: 269 YGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRYADEVRKVFHVGLKE 328
Y R + R + + + E L+ +I+AY K R A K ++
Sbjct: 1070 YQSTSREVRRLDSVTRSPIYALFGEALNGLSSIRAY----KAYDRMAKINGKSMDNNIRF 1125
Query: 329 ALTSG---------------------AFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGD 367
L S A F V + GN A+ + ++ + + +
Sbjct: 1126 TLASTSSNRWLTIRSESLGGVMIWLTATFAVLRY-GNAENQAVFASTMGLLLSYTLNITT 1184
Query: 368 LSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDPVTLENKS 427
L S ++ + A + E N+R P+ G S
Sbjct: 1185 LLSGVLRQASKAENSLNSVERVGNYIDLPSEATAIIE-NNRPVSGWPSRG---------S 1234
Query: 428 IHFNHVKFSY-PTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGE 486
I F V Y P P + L+F V P E V +VG +G GKS++ + L R ++ G
Sbjct: 1235 IQFEDVHLRYRPGLPP--VLHGLSFFVYPSEKVGVVGRTGAGKSSMLNALYRIVELEKGR 1292
Query: 487 IKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQA 546
I + + ++ F L RR + GT+ NI P ND + A+ +A
Sbjct: 1293 ILIDDYDVAKFGLTDLRR-------KQFFLLGTVRFNID---PFSEHNDAD-LWEALERA 1341
Query: 547 NCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEE 606
+ + P GL V G S GQ+Q ++LARA L IL LDEAT+++D +++
Sbjct: 1342 HIKDVIDRNPFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILFLDEATASVDVRTDS 1401
Query: 607 VVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNK 666
++ +++++ + T + IAHR++TI +++VL+ G V E S +L++ S+ K
Sbjct: 1402 LIQRTIRE-EFKSCTMLIIAHRLNTIIDCDKILVLS-SGQVLEYDSPQELLSRDTSAFFK 1459
Query: 667 LL 668
++
Sbjct: 1460 MV 1461
Score = 90.1 bits (222), Expect = 1e-17
Identities = 65/222 (29%), Positives = 107/222 (47%), Gaps = 17/222 (7%)
Query: 435 FSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNI 494
FS+ ++ D+N + G V IVG +G GK+++ S +L GE+ +
Sbjct: 622 FSWDSKTSKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAML-------GELSHAETSS 674
Query: 495 RDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLAN 554
D R + V Q +F+ T+ +NI + E R RAI L
Sbjct: 675 VDI-----RGSVAYVPQVSWIFNATLRENILFGSDFE----SERYWRAIDVTALQHDLDL 725
Query: 555 FPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQ 614
FP +T +G RG +SGGQKQR+++ARA + I I D+ SALD+ V S +
Sbjct: 726 FPGRDRTEIGERGVNISGGQKQRVSMARAVYSNSDIYIFDDPFSALDAHVAHQVFDSCVK 785
Query: 615 RSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
+GKT + + +++ + R+I+++ G + E G+F +L
Sbjct: 786 HELKGKTRVLVTNQLHFLPLMDRIILVS-EGMIKEEGNFAEL 826
>ECU11g1200 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC superfamily
Length = 600
Score = 100 bits (248), Expect = 1e-20
Identities = 68/218 (31%), Positives = 110/218 (50%), Gaps = 8/218 (3%)
Query: 426 KSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSG 485
K+I FN V Y + + +N T+ G+ V IVG +G GKST+ LL++ G
Sbjct: 362 KNIVFNDVHSYYGDKK---VLRGVNLTIEKGDKVAIVGSNGSGKSTILKTLLKFNSY-QG 417
Query: 486 EIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQ 545
I + NI+ +RR +G V Q LF+ T++ NI Y P V+D + A +
Sbjct: 418 SICIDGINIKAIENGSFRRTIGYVPQNSSLFNETVMYNIKYGSPS--VSDYAVVELA-KR 474
Query: 546 ANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSE 605
N + G T VG G +SGG++Q+I + RA L IL++DE TS LD ++E
Sbjct: 475 FNIHDSIMRLERGYFTNVGECGRHISGGERQKIVILRALLKRSEILVMDEPTSNLDKEAE 534
Query: 606 EVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNR 643
+ +++ S T I+I H + + ++V +++
Sbjct: 535 IDIIRNIID-SEGSVTVIAIVHNLDLLPFFNKVCFVDK 571
>ECU03g0240 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC superfamily
Length = 585
Score = 99.4 bits (246), Expect = 2e-20
Identities = 67/218 (30%), Positives = 111/218 (50%), Gaps = 6/218 (2%)
Query: 440 RPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNL 499
R + I ++++FT+ GE + I GP+G GKST + LLR+ D SGEI + +R +
Sbjct: 351 RGEKTILKEISFTLHKGEKLAIAGPNGAGKSTFINTLLRFLDY-SGEILIDGVEMRKYTR 409
Query: 500 RKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGL 559
R R+++ V Q+ + T+L N+ Y I + G + +N G
Sbjct: 410 RSTRQIMAYVPQDNCIVDDTVLRNLQYGNKDISFEKIKEICKRYGTH---EVFSNLEGGY 466
Query: 560 QTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARG 619
G +G +LS GQKQ ++L RA + D I ILDEATS +D ++E + + A
Sbjct: 467 FKEAGQQGCELSVGQKQYLSLMRAIIKDAPIFILDEATSDVDYKTETELIDYVMSVLA-D 525
Query: 620 KTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+T I I H S ++ ++ L ++ T+ G+ +L+
Sbjct: 526 RTIIMIVHNHSLLKKFDNILFL-KNKTMKGYGNIKELL 562
>At1g67940 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 263
Score = 99.0 bits (245), Expect = 2e-20
Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 14/208 (6%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
I + + + G V ++GPSG GKST L R ++ + L ++I + ++ RR
Sbjct: 44 ILKGVTIDIPKGMIVGVIGPSGSGKSTFLRSLNRLWEPPESTVFLDGEDITNVDVIALRR 103
Query: 505 LLGVVQQEPMLFSGTILDNITYA--VPQELVNDETRISRAIGQANCTKFLANFPDGLQTT 562
+G++ Q P+LF GT+ DN+ Y + E ++DE + + + A+ A
Sbjct: 104 RVGMLFQLPVLFQGTVADNVRYGPNLRGEKLSDE-EVYKLLSLADLDASFAK-------- 154
Query: 563 VGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSL-QQRSARGKT 621
G +LS GQ QR+ALAR +P +L+LDE TSALD S E + + + + RG T
Sbjct: 155 --KTGAELSVGQAQRVALARTLANEPEVLLLDEPTSALDPISTENIEDVIVKLKKQRGIT 212
Query: 622 TISIAHRVSTIQHSSRVIVLNRHGTVAE 649
T+ ++H + IQ + ++ L G + E
Sbjct: 213 TVIVSHSIKQIQKVADIVCLVVDGEIVE 240
>Hs21729888 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 935
Score = 98.6 bits (244), Expect = 3e-20
Identities = 62/213 (29%), Positives = 104/213 (48%), Gaps = 18/213 (8%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+ ++F VR G+ + I G G GKS++ + LL + G + +
Sbjct: 495 VLHSISFVVRKGKILGICGNVGSGKSSLLAALLGQMQLQKGVVAVNGT------------ 542
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
L V Q+ +F G + +NI + D R + K L+N P G T +G
Sbjct: 543 -LAYVSQQAWIFHGNVRENILFGEKY----DHQRYQHTVRVCGLQKDLSNLPYGDLTEIG 597
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
RG LSGGQ+QRI+LARA D + +LD+ SA+D+ + V + +++ RGKT +
Sbjct: 598 ERGLNLSGGQRQRISLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKKTLRGKTVVL 657
Query: 625 IAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ H++ ++ VI+L G + E G+ +L+
Sbjct: 658 VTHQLQFLESCDEVILL-EDGEICEKGTHKELM 689
>Hs21729886 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1009
Score = 98.6 bits (244), Expect = 3e-20
Identities = 62/213 (29%), Positives = 104/213 (48%), Gaps = 18/213 (8%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+ ++F VR G+ + I G G GKS++ + LL + G + +
Sbjct: 495 VLHSISFVVRKGKILGICGNVGSGKSSLLAALLGQMQLQKGVVAVNGT------------ 542
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
L V Q+ +F G + +NI + D R + K L+N P G T +G
Sbjct: 543 -LAYVSQQAWIFHGNVRENILFGEKY----DHQRYQHTVRVCGLQKDLSNLPYGDLTEIG 597
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
RG LSGGQ+QRI+LARA D + +LD+ SA+D+ + V + +++ RGKT +
Sbjct: 598 ERGLNLSGGQRQRISLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKKTLRGKTVVL 657
Query: 625 IAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+ H++ ++ VI+L G + E G+ +L+
Sbjct: 658 VTHQLQFLESCDEVILL-EDGEICEKGTHKELM 689
>7301180 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1239
Score = 97.8 bits (242), Expect = 5e-20
Identities = 103/465 (22%), Positives = 198/465 (42%), Gaps = 24/465 (5%)
Query: 184 LRTRTMKAALEQDATFLDHNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGM 243
L R L F D G +++R S D G + + + + + D + + F +
Sbjct: 731 LHDRMFACILHATMRFFDTTPSGRILNRFSKDMGAIDELLPRAMMDFIQIALVMFGILIV 790
Query: 244 MSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQ---LQTSVGELTKVSEEQLSATKT 300
+ ++ L M+++A ++ +Y + ++L R ++ V S L+ ++
Sbjct: 791 IGILNPVLVAAMLVVAVVDVLILKLYLRPSQDLKRLEGICRSPVFSHLSASLTGLAIIRS 850
Query: 301 IQAYCGEKKEIHRYADEVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKT 360
Q KE D V+ + + T G + + +T + +I +
Sbjct: 851 RQLQDVVAKEFDLLQDVHSSVWQLTMAVNTTLGLWLDCVS-----CIFLTSVTFSFIISS 905
Query: 361 GLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKDP 420
G++ + A+ E ++ + RV + + + P +G+
Sbjct: 906 ETTYSGNVGLAIAQAMILTGMVQYGVRQVAESLQQMTSVERVLQYTELEQ--EPALGEKT 963
Query: 421 VTLE---NKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLL 477
+ + F ++ Y + +LN T+ G V IVG +G GKS++ L
Sbjct: 964 PPQQWPTRGQVEFRNMSCRYDPNGSP-VLRNLNLTIEAGWKVGIVGRTGAGKSSLIGALF 1022
Query: 478 RYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDET 537
R I GEI + +L R + ++ Q+P+LFS TI N+ P E D
Sbjct: 1023 RLAHI-EGEIFIDGIETGTISLEILRTRISIIPQDPVLFSATIRYNLD---PFERYTD-A 1077
Query: 538 RISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEAT 597
+ A+ K + GL V RG S GQ+Q + LARA L + +L+LDEAT
Sbjct: 1078 ELWSALEDVELRKAIP----GLDYMVTERGGNFSVGQRQLLCLARAILRNNKVLVLDEAT 1133
Query: 598 SALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLN 642
+ +D Q++ ++ ++++ + + T +++AHR+ T+ S R+IV++
Sbjct: 1134 ANVDPQTDALIQRTIRIK-FKQCTVLTVAHRLHTVMDSDRIIVMD 1177
Score = 87.4 bits (215), Expect = 7e-17
Identities = 65/240 (27%), Positives = 112/240 (46%), Gaps = 26/240 (10%)
Query: 424 ENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG 483
+++++ + S+ + +N + G+ ++GP G GKS++ LLL +
Sbjct: 328 DSRAVTIKDINASWDIEKPQKTLQSINLQIEKGQLCAVIGPVGAGKSSILQLLLGELPVI 387
Query: 484 SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAI 543
G + + D L QEP LF+G++ +NI + +E D R
Sbjct: 388 DGGVFIQGD-------------LSYAAQEPWLFTGSVRNNILFG--EEF--DRKRYQEVT 430
Query: 544 GQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQ 603
+ P+G +T VG RG LSGGQ+ RI+LARA I ++D+ SA+D+
Sbjct: 431 RCCALSTDFQQLPNGDKTLVGERGASLSGGQRARISLARAVYKPAQIYLMDDPLSAVDAH 490
Query: 604 -----SEEVVAQSLQQRSARGKTT-ISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+EV+ + R A+ K T I + H+V + + VIV+ G + G++ +LI
Sbjct: 491 VGRHLFDEVIGP--RGRLAQLKATRILVTHQVHFLSEAD-VIVIVDQGRILRQGTYQELI 547
>Hs6995996 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1480
Score = 95.9 bits (237), Expect = 2e-19
Identities = 64/213 (30%), Positives = 112/213 (52%), Gaps = 7/213 (3%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
I E+++F++ PG+ V ++G +G GKST+ S LR + GEI++ + L+++R+
Sbjct: 1226 ILENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNT-EGEIQIDGVSWDSITLQQWRK 1284
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
GV+ Q+ +FSGT N+ P E +D+ I + + + FP L +
Sbjct: 1285 AFGVIPQKVFIFSGTFRKNLD---PYEQWSDQ-EIWKVADEVGLRSVIEQFPGKLDFVLV 1340
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
G LS G KQ + LAR+ L IL+LDE ++ LD + +++ ++L+Q A T I
Sbjct: 1341 DGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLKQAFA-DCTVIL 1399
Query: 625 IAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
HR+ + + +V+ + V + S KL+
Sbjct: 1400 CEHRIEAMLECQQFLVIEEN-KVRQYDSIQKLL 1431
Score = 80.1 bits (196), Expect = 1e-14
Identities = 54/224 (24%), Positives = 105/224 (46%), Gaps = 18/224 (8%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+ +D+NF + G+ + + G +G GK+++ +++ + G+IK +
Sbjct: 440 VLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIK-------------HSG 486
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
+ Q + GTI +NI + V DE R I + ++ F + +G
Sbjct: 487 RISFCSQFSWIMPGTIKENIIFGVSY----DEYRYRSVIKACQLEEDISKFAEKDNIVLG 542
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
G LSGGQ+ RI+LARA D + +LD LD +E+ + +S + KT I
Sbjct: 543 EGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTRIL 602
Query: 625 IAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLL 668
+ ++ ++ + ++++LN G+ G+F +L + +KL+
Sbjct: 603 VTSKMEHLKKADKILILN-EGSSYFYGTFSELQNLQPDFSSKLM 645
>Hs21729876 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1344
Score = 91.7 bits (226), Expect = 4e-18
Identities = 117/527 (22%), Positives = 209/527 (39%), Gaps = 75/527 (14%)
Query: 175 VTGERLVARLRTRTMKAALEQDATFLD--HNRVGDLISRLSSDAGIVSKSVTQN---LSD 229
+ +R R R A E+ F H G+ IS + D + + V L
Sbjct: 225 IINQRTAIRFRAAVSSFAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLIT 284
Query: 230 GTRAVIQGFVGFGMMSFISWKLTCVMMLLAPPLGVMALVYGKRIRNLSRQLQTSVGELTK 289
VI + ++ + ++ + + LL PL V + ++ + ++ + +
Sbjct: 285 CASLVICSISSYFIIGYTAF-IAILCYLLVFPLAVFMTRMAVKAQHHTSEVSD---QRIR 340
Query: 290 VSEEQLSATKTIQAYCGEK---KEIHRYADEVRKVFH-VGLKEALTSGAFFGVTGFVGNV 345
V+ E L+ K I+ Y EK K I + RK+ GL ++LTS F +
Sbjct: 341 VTSEVLTCIKLIKMYTWEKPFAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVA--T 398
Query: 346 ALLALLLTGTSMIKTGLMTVGDLSSFMMYAVXXXXXXXXXXXXXXELMKGAGAAARVFEL 405
A+ L+ T + T M L+S + + K A + F L
Sbjct: 399 AVWVLIHTSLKLKLTASMAFSMLASLNLLRLSVFFVPIAVKGLTNS--KSAVMRFKKFFL 456
Query: 406 NDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYP-----------------------TRPQ 442
+ P+ + +DP +K++ F S+ TRP+
Sbjct: 457 QE-SPVFYVQTLQDP----SKALVFEEATLSWQQTCPGIVNGALELERNGHASEGMTRPR 511
Query: 443 HHI------------FEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLG 490
+ +N V G + + G +G GKS++ S +L + G + +
Sbjct: 512 DALGPEEEGNSLGPELHKINLVVSKGMMLGVCGNTGSGKSSLLSAILEEMHLLEGSVGVQ 571
Query: 491 NDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTK 550
L V Q+ + SG I +NI D+ R + + + +
Sbjct: 572 GS-------------LAYVPQQAWIVSGNIRENILMGGAY----DKARYLQVLHCCSLNR 614
Query: 551 FLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQ 610
L P G T +G RG LSGGQKQRI+LARA D I +LD+ SA+D+ + + +
Sbjct: 615 DLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDPLSAVDAHVGKHIFE 674
Query: 611 SLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
+++ RGKT + + H++ ++ ++I+L +G + E G+ +L+
Sbjct: 675 ECIKKTLRGKTVVLVTHQLQYLEFCGQIILL-ENGKICENGTHSELM 720
Score = 69.3 bits (168), Expect = 2e-11
Identities = 59/225 (26%), Positives = 105/225 (46%), Gaps = 44/225 (19%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+ +N T+R E V IVG +G GKS++ L R + +G I + +I L R
Sbjct: 1157 VLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRILIDGVDICSIGLEDLRS 1216
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
L V+ Q+P+L SGTI N+ P + D
Sbjct: 1217 KLSVIPQDPVLLSGTIRFNLD---PFDRHTD----------------------------- 1244
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
Q+ AL R F L +I+++DEAT+++D +++ ++ +++++ + +G T +
Sbjct: 1245 ---------QQIWDALERTF-LTKAIILIDEATASIDMETDTLIQRTIRE-AFQGCTVLV 1293
Query: 625 IAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLLS 669
IAHRV+T+ + ++V+ +G V E + L P S L++
Sbjct: 1294 IAHRVTTVLNCDHILVMG-NGKVVEFDRPEVLRKKPGSLFAALMA 1337
>YKR104w [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 306
Score = 89.0 bits (219), Expect = 2e-17
Identities = 60/210 (28%), Positives = 113/210 (53%), Gaps = 16/210 (7%)
Query: 447 EDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLL 506
++++F V+ G V IVG +G GKS++ + + R D +G I + N +I+ L + R +
Sbjct: 51 DNVSFKVKAGTKVGIVGRTGAGKSSIIAAIYRLSDWENGTITIDNKDIKHIPLERLRNSI 110
Query: 507 GVVQQEPMLFSGTILDNI----------TYAVPQEL----VNDETRISRAIGQANCTKF- 551
+ Q+P LF GT+ N+ Y V ++ DE + Q N +
Sbjct: 111 SCIPQDPTLFDGTVRSNLDPFDRYSDVQIYGVLSKVGLIEECDELCLIFEQEQPNFSSHK 170
Query: 552 LANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQS 611
L N L T V G+ LS GQ+Q + LAR+ L +I+++DEAT+++D S+ + ++
Sbjct: 171 LRNRFIDLNTVVKSGGSNLSQGQRQLLCLARSMLGARNIMLIDEATASIDYISDAKIQKT 230
Query: 612 LQQRSARGKTTISIAHRVSTIQHSSRVIVL 641
+++ + + T ++IAHR+ ++ +++V+
Sbjct: 231 IRE-TMKNTTILTIAHRLRSVIDYDKILVM 259
>CE27270 [U] KOG0058 Peptide exporter ABC superfamily
Length = 490
Score = 86.7 bits (213), Expect = 1e-16
Identities = 66/173 (38%), Positives = 98/173 (56%), Gaps = 10/173 (5%)
Query: 502 YRRLLGVVQQEPMLFS------GTILDNITYAVPQELVNDETRISRAIGQANCTKFLANF 555
Y L G ++ E + FS T+ +N+T ++P V S G++ T L F
Sbjct: 315 YHSLWGDIKFEDVSFSYPTRPGHTVFENLTLSIPAGQVVALCGPSGE-GKSTITHLLERF 373
Query: 556 PDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQR 615
+ V G L G QKQRIA+ARA L +P ILILDEATSALDS SE +V ++L
Sbjct: 374 YEPKSGRVTLDGRDLRG-QKQRIAIARAILKNPPILILDEATSALDSHSEHMVQEAL-NN 431
Query: 616 SARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIAIPDSSLNKLL 668
+G+T + IAHR+STI+ S+++I + + E+G+ ++L+A S KL+
Sbjct: 432 VMKGRTVLIIAHRLSTIR-SAQMIYVIKDKKALESGTHEQLMAKKGSLYRKLV 483
Score = 82.8 bits (203), Expect = 2e-15
Identities = 67/215 (31%), Positives = 102/215 (47%), Gaps = 14/215 (6%)
Query: 317 EVRKVFHVGLKEALTSGAFFGVTGFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYAV 376
E + F + + + L + F G +G++ L+ +T ++ G MT G L SF++ A
Sbjct: 214 EFKSSFKLCVSQGLRT--FAQTIGCIGSLYFLSPTMTMYTV--AGEMTPGALMSFLVSAQ 269
Query: 377 XXXXXXXXXXXXXXELMKGAGAAARVFELNDRKPLIHPTIGKD-PVTLENKSIHFNHVKF 435
+KG A RV + + +P I G P I F V F
Sbjct: 270 TIQRSLSQLSIIFGTAIKGWTAGGRVLQFSRLEPSIPMDTGVCIPYHSLWGDIKFEDVSF 329
Query: 436 SYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIR 495
SYPTRP H +FE+L ++ G+ V + GPSG GKST+ LL R+Y+ SG + L R
Sbjct: 330 SYPTRPGHTVFENLTLSIPAGQVVALCGPSGEGKSTITHLLERFYEPKSGRVTLDG---R 386
Query: 496 DFNLRKYRRLL--GVVQQEPMLFSGTILDNITYAV 528
D +K R + +++ P+L ILD T A+
Sbjct: 387 DLRGQKQRIAIARAILKNPPIL----ILDEATSAL 417
>ECU04g0480 [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC superfamily
Length = 555
Score = 84.3 bits (207), Expect = 6e-16
Identities = 53/201 (26%), Positives = 93/201 (45%), Gaps = 5/201 (2%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+ +N + GE + I G +G GK++ LL ++D SG I + + N R+
Sbjct: 357 LIRGVNMDIGKGEKIGISGDNGSGKTSFIRALLGFFDY-SGSILVDGIELSTLNKEGLRQ 415
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
++ QE LF+ +I+ NI + I + G + + DG QT VG
Sbjct: 416 MISYSPQESQLFNESIISNIKDGNIYMSDEEAVEICKKYGMDD---MFTSLDDGYQTLVG 472
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
RG +LSGGQ+Q++++ R + D I I D+ TS +D +SE + + ++ KT I
Sbjct: 473 NRGNRLSGGQRQKVSMMRTVVKDAPIYIFDQVTSHVDKESENNMVDMI-MKNLSDKTVIM 531
Query: 625 IAHRVSTIQHSSRVIVLNRHG 645
+ + ++ + G
Sbjct: 532 VVQNSDLLDRFDKIYYFSNGG 552
>YKR103w [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1218
Score = 82.8 bits (203), Expect = 2e-15
Identities = 63/201 (31%), Positives = 96/201 (47%), Gaps = 8/201 (3%)
Query: 461 IVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRD---FNLRKYRRLLGVVQQEPMLFS 517
I+GP+G GKS++ LL ++ SG+I + RD + Q P L S
Sbjct: 684 IIGPTGSGKSSLLLGLLGELNLLSGKIYVPTVESRDDLEIGKDGMTNSMAYCSQTPWLIS 743
Query: 518 GTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQR 577
GTI DN+ + E+ N + + + K + G++T VG G LSGGQ+QR
Sbjct: 744 GTIKDNVVFG---EIFNKQ-KFDDVMKSCCLDKDIKAMTAGIRTDVGDGGFSLSGGQQQR 799
Query: 578 IALARAFLLDPSILILDEATSALDSQSE-EVVAQSLQQRSARGKTTISIAHRVSTIQHSS 636
IALARA LILD+ SA+D ++ + + L +G+T I +H +S + +
Sbjct: 800 IALARAIYSSSRYLILDDCLSAVDPETALYIYEECLCGPMMKGRTCIITSHNISLVTKRA 859
Query: 637 RVIVLNRHGTVAETGSFDKLI 657
+V+ G V G LI
Sbjct: 860 DWLVILDRGEVKSQGKPSDLI 880
>Hs9955972 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1238
Score = 82.4 bits (202), Expect = 2e-15
Identities = 71/259 (27%), Positives = 118/259 (45%), Gaps = 31/259 (11%)
Query: 419 DPVTLENKSI--------HFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKS 470
DP ++E K+I H ++ P H L+ V G V +VGP G GKS
Sbjct: 612 DPQSVERKTISPGYAITIHSGTFTWAQDLPPTLH---SLDIQVPKGALVAVVGPVGCGKS 668
Query: 471 TVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQ 530
++ S LL + G++ + + V Q+ + + T+ +N+ +
Sbjct: 669 SLVSALLGEMEKLEGKVHMKGS-------------VAYVPQQAWIQNCTLQENVLFG--- 712
Query: 531 ELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSI 590
+ +N + R + + L P G QT +G +G LSGGQ+QR++LARA D I
Sbjct: 713 KALNPK-RYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADI 771
Query: 591 LILDEATSALDSQSEEVVAQSL--QQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVA 648
+LD+ SA+DS + + + + GKT + + H +S + + +IVL G V+
Sbjct: 772 FLLDDPLSAVDSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVL-ADGQVS 830
Query: 649 ETGSFDKLIAIPDSSLNKL 667
E G + L+ S N L
Sbjct: 831 EMGPYPALLQRNGSFANFL 849
>At5g06530 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 567
Score = 80.9 bits (198), Expect = 6e-15
Identities = 70/262 (26%), Positives = 127/262 (47%), Gaps = 34/262 (12%)
Query: 399 AARVFELNDRKPLIH--PTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPG 456
+A E +KP PT+ P+ L+ + + + V + + I ++ +V PG
Sbjct: 10 SAEDIEAGKKKPKFQAEPTL---PIFLKFRDVTYKVVIKKLTSSVEKEILTGISGSVNPG 66
Query: 457 EHVCIVGPSGGGKSTVASLLL-RYYDIGSGEIKLGNDNIRDFNLRKY-RRLLGVVQQEPM 514
E + ++GPSG GK+T+ SLL R +G G+ D KY + +G V Q+ +
Sbjct: 67 EVLALMGPSGSGKTTLLSLLAGRISQSSTG----GSVTYNDKPYSKYLKSKIGFVTQDDV 122
Query: 515 LFSG-TILDNITYA----VPQELVNDETR-----ISRAIGQANCTKFLANFPDGLQTTVG 564
LF T+ + +TYA +P+ L ++ + + + +G C T +G
Sbjct: 123 LFPHLTVKETLTYAARLRLPKTLTREQKKQRALDVIQELGLERCQ----------DTMIG 172
Query: 565 PRGTQ-LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTI 623
+ +SGG+++R+++ +++PS+L+LDE TS LDS + L + GKT I
Sbjct: 173 GAFVRGVSGGERKRVSIGNEIIINPSLLLLDEPTSGLDSTTALRTILMLHDIAEAGKTVI 232
Query: 624 SIAHRVST--IQHSSRVIVLNR 643
+ H+ S+ ++I+L R
Sbjct: 233 TTIHQPSSRLFHRFDKLILLGR 254
>At3g21090 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 680
Score = 80.9 bits (198), Expect = 6e-15
Identities = 63/197 (31%), Positives = 99/197 (49%), Gaps = 13/197 (6%)
Query: 441 PQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL---LRYYDIGSGEIKLGNDNIR-D 496
P + + LN PG + I+GPSG GKST+ L L + +G + L R D
Sbjct: 41 PTRRLLQRLNGYAEPGRIMAIMGPSGSGKSTLLDSLAGRLARNVVMTGNLLLNGKKARLD 100
Query: 497 FNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETR--ISRAIGQANCTKFLAN 554
+ L Y V Q++ +L + T+ + ITY+ L +D ++ +S + L +
Sbjct: 101 YGLVAY-----VTQEDVLLGTLTVRETITYSAHLRLPSDMSKEEVSDIVEGTIMELGLQD 155
Query: 555 FPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQ 614
D + RG +SGG+++R+++A L P IL LDE TS LDS S V Q+L+
Sbjct: 156 CSDRVIGNWHARG--VSGGERKRVSIALEILTRPQILFLDEPTSGLDSASAFFVIQALRN 213
Query: 615 RSARGKTTISIAHRVST 631
+ G+T IS H+ S+
Sbjct: 214 IARDGRTVISSVHQPSS 230
>At4g25750 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 577
Score = 80.5 bits (197), Expect = 8e-15
Identities = 71/247 (28%), Positives = 121/247 (48%), Gaps = 21/247 (8%)
Query: 423 LENKSIHFNHVKFSYPTRP-------QHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASL 475
+E+ ++ + + ++ P P I ++ T P + + I+GPSG GKST+ +
Sbjct: 1 MESYTLSTSSISYAKPLSPLLLTAEQPSFILRNITLTSHPSQILAIIGPSGAGKSTLLDI 60
Query: 476 LLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSG-TILDNITYAVPQELVN 534
L SG I L + I N YR++ V Q F T+ + T++ L
Sbjct: 61 LAARTSPTSGSILLNSVLI---NPSSYRKISSYVPQHDTFFPLLTVSETFTFSASLLLPK 117
Query: 535 DETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILD 594
+ +++S + A+ K L N T +G LSGG+++R+++ + L DP +L+LD
Sbjct: 118 NLSKVSSVV--ASLLKEL-NLTHLAHTRLGQG---LSGGERRRVSIGLSLLHDPEVLLLD 171
Query: 595 EATSALDSQSEEVVAQSLQQ-RSARGKTTISIAHRVS--TIQHSSRVIVLNRHGTVAETG 651
E TS LDS+S V Q L+ ++R + I H+ S + RV++L++ GT+ G
Sbjct: 172 EPTSGLDSKSAFDVVQILKSIATSRERIVILSIHQPSFKILSLIDRVLLLSK-GTIVYHG 230
Query: 652 SFDKLIA 658
D L A
Sbjct: 231 RLDLLEA 237
>At5g52860 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 589
Score = 79.7 bits (195), Expect = 1e-14
Identities = 77/249 (30%), Positives = 119/249 (46%), Gaps = 29/249 (11%)
Query: 422 TLENKSIHFNHVKFS-----YP-TRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASL 475
TL SI + K S +P T P I ++ T P E + +VGPSG GKST+ +
Sbjct: 15 TLTTSSISYTIPKTSLSLLRFPATEPPSFILRNITLTAHPTEILAVVGPSGAGKSTLLDI 74
Query: 476 LLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSG-TILDNITYA----VPQ 530
L SG I L + I N YR++ V Q F T+ + ++A +P
Sbjct: 75 LASKTSPTSGSILLNSIPI---NPSSYRKISSYVPQHDSFFPLLTVSETFSFAACLLLPN 131
Query: 531 ELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSI 590
+ ET ++ + + N T L T +G LSGG+++R+++ + L DP
Sbjct: 132 PSIVSET-VTSLLSELNLTH--------LSHTRLAQG--LSGGERRRVSIGLSLLHDPCF 180
Query: 591 LILDEATSALDSQSEEVVAQSLQQRS-ARGKTTISIAHRVS--TIQHSSRVIVLNRHGTV 647
L+LDE TS LDS+S V L+ + +R +T I H+ S + R+++L++ GTV
Sbjct: 181 LLLDEPTSGLDSKSAFDVIHILKSIAVSRQRTVILSIHQPSFKILSIIDRLLLLSK-GTV 239
Query: 648 AETGSFDKL 656
G D L
Sbjct: 240 VYHGRLDSL 248
>At2g37010 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 386
Score = 79.7 bits (195), Expect = 1e-14
Identities = 60/231 (25%), Positives = 112/231 (47%), Gaps = 16/231 (6%)
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYR 503
HI + + PG ++GPSG GK+T S L G L N R+ ++ Y+
Sbjct: 24 HILRSVTGKIMPGRVSAVMGPSGAGKTTFLSALAGKAT-GCTRTGLILINGRNDSINSYK 82
Query: 504 RLLGVVQQEPMLFSG-TILDNITYAVPQELVNDETRISRAIGQANCTKFLA--NFPDGLQ 560
++ G V Q+ ++ T+ +N+ ++ L ++ + + + L + D L
Sbjct: 83 KITGFVPQDDVVHGNLTVEENLRFSARCRLSAYMSKADKVLIIERVIESLGLQHVRDSLV 142
Query: 561 TTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGK 620
T+ RG +SGGQ++R+ + +++PS+LILDE T+ LDS S +++ ++L++ + G
Sbjct: 143 GTIEKRG--ISGGQRKRVNVGVEMVMEPSLLILDEPTTGLDSASSQLLLRALRREALEGV 200
Query: 621 TTISIAHRVSTIQHS--SRVIVLNRHGTVAETGSFDKL--------IAIPD 661
+ H+ S + +I+L + G GS K+ I +PD
Sbjct: 201 NICMVVHQPSYTMYKMFDDMIILAKGGLTVYHGSVKKIEEYFADIGITVPD 251
>Hs4506341 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 659
Score = 79.0 bits (193), Expect = 2e-14
Identities = 69/236 (29%), Positives = 107/236 (45%), Gaps = 28/236 (11%)
Query: 417 GKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL 476
G + + + I F+HV + P + DLNF VR G +V I GP+G GKS++ +L
Sbjct: 429 GAGEIIIADNIIKFDHVPLATPNGDV--LIRDLNFEVRSGANVLICGPNGCGKSSLFRVL 486
Query: 477 LRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDE 536
+ + G + + R L V Q P + GT+ D + Y +E D+
Sbjct: 487 GELWPLFGGRLT-----------KPERGKLFYVPQRPYMTLGTLRDQVIYPDGRE---DQ 532
Query: 537 TRISRAIGQANCTKFLANFPDG--LQTTVGPRGTQ-----LSGGQKQRIALARAFLLDPS 589
R + I ++L N G L+ G Q LSGG+KQR+A+AR F P
Sbjct: 533 KR--KGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQ 590
Query: 590 ILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHG 645
ILDE TSA+ E + ++ G T +++HR S +H + ++ G
Sbjct: 591 FAILDECTSAVSVDVEGYIYSHCRK---VGITLFTVSHRKSLWKHHEYYLHMDGRG 643
>At1g31770 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 646
Score = 79.0 bits (193), Expect = 2e-14
Identities = 59/214 (27%), Positives = 102/214 (47%), Gaps = 25/214 (11%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLL-RYYDIGSGEIKLGNDNIRDFNLRKYR 503
I + V PGE + ++GPSG GK+T+ S L R SG++ +
Sbjct: 79 ILNGITGMVCPGEFLAMLGPSGSGKTTLLSALGGRLSKTFSGKVMYNGQPFSGC----IK 134
Query: 504 RLLGVVQQEPMLFSG-----TILDNITYAVPQELVNDET-----RISRAIGQANCTKFLA 553
R G V Q+ +L+ T+ +P L DE R+ +G CT +
Sbjct: 135 RRTGFVAQDDVLYPHLTVWETLFFTALLRLPSSLTRDEKAEHVDRVIAELGLNRCTNSMI 194
Query: 554 NFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQ 613
GP +SGG+K+R+++ + L++PS+L+LDE TS LDS + + +++
Sbjct: 195 G---------GPLFRGISGGEKKRVSIGQEMLINPSLLLLDEPTSGLDSTTAHRIVTTIK 245
Query: 614 QRSARGKTTISIAHRVST-IQHSSRVIVLNRHGT 646
+ ++ G+T ++ H+ S+ I H +VL G+
Sbjct: 246 RLASGGRTVVTTIHQPSSRIYHMFDKVVLLSEGS 279
>Hs9955956 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1466
Score = 78.6 bits (192), Expect = 3e-14
Identities = 63/244 (25%), Positives = 112/244 (45%), Gaps = 28/244 (11%)
Query: 417 GKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL 476
G + +T+ N + F + PT + F++ G V +VG G GKS++ S L
Sbjct: 640 GTNSITVRNAT--FTWARSDPPT------LNGITFSIPEGALVAVVGQVGCGKSSLLSAL 691
Query: 477 LRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDE 536
L D G + + + V Q+ + + ++ +NI + E E
Sbjct: 692 LAEMDKVEGHVAIKGS-------------VAYVPQQAWIQNDSLRENILFGCQLE----E 734
Query: 537 TRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEA 596
I L P G +T +G +G LSGGQKQR++LARA + I + D+
Sbjct: 735 PYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDP 794
Query: 597 TSALDSQSEEVVAQSL--QQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFD 654
SA+D+ + + +++ + + KT I + H +S + +IV++ G ++E GS+
Sbjct: 795 LSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMS-GGKISEMGSYQ 853
Query: 655 KLIA 658
+L+A
Sbjct: 854 ELLA 857
Score = 70.1 bits (170), Expect = 1e-11
Identities = 98/447 (21%), Positives = 176/447 (38%), Gaps = 63/447 (14%)
Query: 152 YTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLDHNRVGDLISR 211
Y ALG + +A G + + + G L + + L +F + G+L++R
Sbjct: 1019 YGALG---ISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNR 1075
Query: 212 LSSDAGIVSKSVTQNLSDGTRAVIQGFVGFGMMSFISWKLTCVMMLLA--------PPLG 263
S + V + + VI+ F+G S + C+++LLA PPLG
Sbjct: 1076 FSKELDTVDSMIPE--------VIKMFMG----SLFNVIGACIVILLATPIAAIIIPPLG 1123
Query: 264 VMALV----YGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKEIHRY---AD 316
++ Y R L R S + E L I+A+ +++ IH+ D
Sbjct: 1124 LIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVD 1183
Query: 317 EVRKVFHVGLKEALTSGAFFGVT-GFVGNVALLALLLTGTSMIKTGLMTVGDLSSFMMYA 375
E +K ++ ++ + + V VGN +L L ++I ++ G + + Y+
Sbjct: 1184 ENQKAYY----PSIVANRWLAVRLECVGNCIVLFAALF--AVISRHSLSAGLVGLSVSYS 1237
Query: 376 VXXXXXXXXXXXXXXELMKGAGAAARVFELNDRK------------PLIHPTIGKDPVTL 423
+ E+ A R+ E ++ + P P +G+
Sbjct: 1238 LQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGR----- 1292
Query: 424 ENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG 483
+ F + Y + +N T+ GE V IVG +G GKS++ L R +
Sbjct: 1293 ----VEFRNYCLRY-REDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESA 1347
Query: 484 SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAI 543
GEI + NI L R + ++ Q+P+LFSG++ N+ P +DE + ++
Sbjct: 1348 EGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLD---PFSQYSDE-EVWTSL 1403
Query: 544 GQANCTKFLANFPDGLQTTVGPRGTQL 570
A+ F++ PD L G L
Sbjct: 1404 ELAHLKDFVSALPDKLDHECAEGGENL 1430
>At1g65410 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 294
Score = 78.6 bits (192), Expect = 3e-14
Identities = 66/231 (28%), Positives = 108/231 (46%), Gaps = 26/231 (11%)
Query: 423 LENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDI 482
LEN S + Y + + HI + ++F +R GE V ++GPSG GKST+ ++
Sbjct: 7 LENDSDVLIECRDVYKSFGEKHILKGVSFKIRHGEAVGVIGPSGTGKSTILKIMAGLLAP 66
Query: 483 GSGEIKLGNDN----IRDFNLRKYRRLLGVVQQEPMLF-SGTILDNITYAVPQELVNDET 537
GE+ + I D + R +G+V Q LF S ++ +N+ + + + E
Sbjct: 67 DKGEVYIRGKKRAGLISDEEISGLR--IGLVFQSAALFDSLSVRENVGFLLYERSKMSEN 124
Query: 538 RISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLD-------PSI 590
+IS + Q GL+ ++LSGG K+R+ALAR+ + D P +
Sbjct: 125 QISELVTQTLAAV-------GLKGVENRLPSELSGGMKKRVALARSLIFDTTKEVIEPEV 177
Query: 591 LILDEATSALDSQSEEVVAQSLQ-----QRSARGKTTISIAHRVSTIQHSS 636
L+ DE T+ LD + VV ++ A GK ++ V T QHS+
Sbjct: 178 LLYDEPTAGLDPIASTVVEDLIRSVHMTDEDAVGKPGKIASYLVVTHQHST 228
>At5g60740 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 1061
Score = 76.6 bits (187), Expect = 1e-13
Identities = 61/227 (26%), Positives = 116/227 (50%), Gaps = 26/227 (11%)
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYD--IGSGEIKLGNDNIRDFNLRK 501
H+ + + PG ++GPSG GK+T + L I +G I L N + +++
Sbjct: 514 HLMRCVTGKLSPGRVSAVMGPSGAGKTTFLTALTGKAPGCIMTGMI-LVNGKVE--SIQS 570
Query: 502 YRRLLGVVQQEPMLFSG-TILDNITYA----VPQELVNDET-----RISRAIGQANCTKF 551
Y++++G V Q+ ++ T+ +N+ ++ +P +L E R+ ++G
Sbjct: 571 YKKIIGFVPQDDIVHGNLTVEENLWFSARCRLPADLPKPEKVLVVERVIESLG------- 623
Query: 552 LANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQS 611
L + D L TV RG +SGGQ++R+ + +++PS+LILDE TS LDS S +++ ++
Sbjct: 624 LQHVRDSLVGTVEKRG--ISGGQRKRVNVGLEMVMEPSLLILDEPTSGLDSSSSQLLLRA 681
Query: 612 LQQRSARGKTTISIAHRVS--TIQHSSRVIVLNRHGTVAETGSFDKL 656
L++ + G + H+ S + +I+L + G + G K+
Sbjct: 682 LRREALEGVNICMVVHQPSYTLFRMFDDLILLAKGGLICYQGPVKKV 728
>At3g25620 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 646
Score = 76.6 bits (187), Expect = 1e-13
Identities = 54/204 (26%), Positives = 105/204 (51%), Gaps = 18/204 (8%)
Query: 436 SYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLL-RYYDIGSGEIKLGNDNI 494
S +P + + ++ V+PGE + ++GPSG GK+T+ + L R SG + +
Sbjct: 89 SQEPKPNRLVLKCVSGIVKPGELLAMLGPSGSGKTTLVTALAGRLQGKLSGTVSYNGEPF 148
Query: 495 RDFNLRKYRRLLGVVQQEPMLFSG-TILDNITYA----VPQELVNDET--RISRAIGQAN 547
+R G V Q+ +L+ T+++ +TY +P+EL E ++ +
Sbjct: 149 TS----SVKRKTGFVTQDDVLYPHLTVMETLTYTALLRLPKELTRKEKLEQVEMVVSDLG 204
Query: 548 CTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEV 607
T+ + G RG +SGG+++R+++ + L++PS+L+LDE TS LDS +
Sbjct: 205 LTRCCNSVIGGGLI----RG--ISGGERKRVSIGQEMLVNPSLLLLDEPTSGLDSTTAAR 258
Query: 608 VAQSLQQRSARGKTTISIAHRVST 631
+ +L+ + G+T ++ H+ S+
Sbjct: 259 IVATLRSLARGGRTVVTTIHQPSS 282
>At1g53270 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 590
Score = 76.3 bits (186), Expect = 2e-13
Identities = 70/250 (28%), Positives = 121/250 (48%), Gaps = 31/250 (12%)
Query: 423 LENKSIHF----NHVKFS-----YPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVA 473
LE K++ + N KFS + + I +D++ R E I GPSG GK+T+
Sbjct: 19 LETKNLSYRIGGNTPKFSNLCGLLSEKEEKVILKDVSCDARSAEITAIAGPSGAGKTTLL 78
Query: 474 SLLLRYYDIG--SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSG-TILDNITYAVPQ 530
+L G SG++ + N R + +YRR+ G V QE LF T+ + +TY+
Sbjct: 79 EILAGKVSHGKVSGQVLV---NGRPMDGPEYRRVSGFVPQEDALFPFLTVQETLTYSALL 135
Query: 531 ELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQ-----LSGGQKQRIALARAFL 585
L + R A + + GL+ R Q +SGG+++R+++ +
Sbjct: 136 RL-----KTKRKDAAAKVKRLIQEL--GLEHVADSRIGQGSRSGISGGERRRVSIGVELV 188
Query: 586 LDPSILILDEATSALDSQSEEVVAQSLQQRSAR-GKTTISIAHR--VSTIQHSSRVIVLN 642
DP+++++DE TS LDS S V L+ + + GKT + H+ ++ R+++L+
Sbjct: 189 HDPNVILIDEPTSGLDSASALQVVTLLKDMTIKQGKTIVLTIHQPGFRILEQIDRIVLLS 248
Query: 643 RHGTVAETGS 652
+G V + GS
Sbjct: 249 -NGMVVQNGS 257
>7295829 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 812
Score = 76.3 bits (186), Expect = 2e-13
Identities = 58/216 (26%), Positives = 102/216 (46%), Gaps = 12/216 (5%)
Query: 422 TLENKSIHFNHV----KFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLL 477
T++ +I F ++ KF R + L + GE ++GPSG GKST+ ++L
Sbjct: 142 TIKKINIGFENIRYTTKFGVFQRETKDVLMGLTGYFKSGELSAVIGPSGAGKSTLLNILS 201
Query: 478 RYYDIG-SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDE 536
Y G +G+ ++ N N RD L+ ++ + ++Q+ L + + + +
Sbjct: 202 GYTTYGFTGDFRV-NGNRRD--LKAFKSNVAFIRQDTSLQAFLSVKEAMHFAANLKIGTH 258
Query: 537 TRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEA 596
S + C + T G QLSGGQK+R+A+A + +P +LILDE
Sbjct: 259 MTHSEKRERVKCILEAIGMYENRHTRTG----QLSGGQKKRLAIALELVNNPPVLILDEP 314
Query: 597 TSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTI 632
T+ LDS + + L++ + G+T I H+ S +
Sbjct: 315 TTGLDSFTSNQLINLLKKLAIEGRTVICTIHQPSAL 350
>7295924 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 615
Score = 75.9 bits (185), Expect = 2e-13
Identities = 60/209 (28%), Positives = 104/209 (49%), Gaps = 19/209 (9%)
Query: 428 IHFNHVKF--SYPTRPQHH-IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG- 483
IHF + + + P +P+ + + + T + GE I+GPSG GKS++ ++L G
Sbjct: 15 IHFEDLVYQVNVPKKPEKKSVLKGIKGTFKSGELTAIMGPSGAGKSSLMNILTGLTKSGV 74
Query: 484 SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSG-TILDNITYAVPQELVNDETRISRA 542
SG+I++G K R+L G + Q+ F T+ + + A ++ N +
Sbjct: 75 SGKIEIG----------KARKLCGYIMQDDHFFPYFTVEETMLMAATLKISNQCVSLKE- 123
Query: 543 IGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDS 602
+ +L N L T + + LSGGQK+R+++A + +P++L LDE T+ LDS
Sbjct: 124 --KRTLIDYLLNSLK-LTKTRQTKCSNLSGGQKKRLSIALELIDNPAVLFLDEPTTGLDS 180
Query: 603 QSEEVVAQSLQQRSARGKTTISIAHRVST 631
S Q L+ + G+T + H+ ST
Sbjct: 181 SSSFDTIQLLRGLANEGRTIVCTIHQPST 209
>At4g27420 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 635
Score = 75.5 bits (184), Expect = 3e-13
Identities = 54/189 (28%), Positives = 97/189 (50%), Gaps = 5/189 (2%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRK-YR 503
I + L V+PGE + ++GPSG GK+++ + L G G++ GN + + L K +
Sbjct: 66 ILKGLTGIVKPGEILAMLGPSGSGKTSLLTALGGRVGEGKGKLT-GNISYNNKPLSKAVK 124
Query: 504 RLLGVVQQEPMLFSG-TILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTT 562
R G V Q+ L+ T+ + + + L N + + I QA T
Sbjct: 125 RTTGFVTQDDALYPNLTVTETLVFTALLRLPNSFKKQEK-IKQAKAVMTELGLDRCKDTI 183
Query: 563 VG-PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKT 621
+G P +SGG+++R+++ + L++PS+L LDE TS LDS + + + L + + G+T
Sbjct: 184 IGGPFLRGVSGGERKRVSIGQEILINPSLLFLDEPTSGLDSTTAQRIVSILWELARGGRT 243
Query: 622 TISIAHRVS 630
++ H+ S
Sbjct: 244 VVTTIHQPS 252
>CE25783 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1247
Score = 75.1 bits (183), Expect = 3e-13
Identities = 54/216 (25%), Positives = 106/216 (49%), Gaps = 9/216 (4%)
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG-SGEIKLGNDNIRDFNLRKY 502
H+ +D++ + E + I+G G GKS +A L+ I + + +I + +++
Sbjct: 1026 HVIKDVSLVIEEREKLGIIGKVGSGKSQLAKTLVMMSSADKESHIVVDDLDIFEMSVKTL 1085
Query: 503 RRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTT 562
R + V+ Q+ +FS T+ NI ++ I AI +++ + PDGL
Sbjct: 1086 RSRITVIPQKAKIFSDTLRSNIDPCCQFA----DSDIWLAIEACQLREYVKSLPDGLHQM 1141
Query: 563 VGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTT 622
V P ++S QK ++ + RA L I ++D++T + + +V +++ + S + TT
Sbjct: 1142 VSPE--KMSNEQKCQVNVCRALLKGGQIFVIDQSTKMMKEPIKSLVNEAI-RNSLKQSTT 1198
Query: 623 ISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKLIA 658
I I S ++H RV+V+ +G + T + LI+
Sbjct: 1199 IWIGEDFSDVEHCDRVVVI-ENGVILTTDTPQNLIS 1233
Score = 55.5 bits (132), Expect = 3e-07
Identities = 59/259 (22%), Positives = 114/259 (43%), Gaps = 26/259 (10%)
Query: 403 FELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIV 462
F + + P I+ P + I + FS+ + D+ V+ GE +
Sbjct: 382 FLIVKQSPKINTKTAPQPPVEPDLDIKILNANFSWNGKDD--TLNDVCVHVKKGEKHAFI 439
Query: 463 GPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILD 522
G GKS++ + +GE+K+ N+ + + P +FS ++ +
Sbjct: 440 GFPLCGKSSLLFSI-------TGELKMTKGNMW------VSKGISFAPASPYIFSQSLKE 486
Query: 523 NITYAVPQELVND--ETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIAL 580
NI + ND +++ + I + K + + P T +G +G L+ QK +I+L
Sbjct: 487 NILFG------NDYVKSKYDKVIMACDLKKDIFSLPRCEATVLGDKGYVLTSTQKAQISL 540
Query: 581 ARAFLLDPSILILDEATSALD-SQSEEVVAQSLQQRS-ARGKTTISIAHRVSTIQHSSRV 638
AR D I LD+A +D + S ++ + L + R KT I + + I+ + V
Sbjct: 541 ARCLYEDADIYALDKAFGPMDRTTSNKIFTRVLGENGYLRDKTVILATNNIELIKTFTMV 600
Query: 639 IVLNRHGTVAETGSFDKLI 657
VL ++G + +GS+D+++
Sbjct: 601 HVL-KNGKIETSGSYDQIL 618
>At1g53390 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 1096
Score = 74.7 bits (182), Expect = 5e-13
Identities = 64/259 (24%), Positives = 124/259 (47%), Gaps = 29/259 (11%)
Query: 424 ENKSIHFNHV---KFSYPTRPQHHI---FEDLNFTVR---------------PGEHVCIV 462
ENK++ F+ + + TR +H + F+DL T++ PG ++
Sbjct: 451 ENKNLTFSGIVKMATNSETRKRHLMELSFKDLTLTLKSNGKQVLRCVTGSMKPGRITAVM 510
Query: 463 GPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSG-TIL 521
GPSG GK+++ S L +G L N + ++ Y++++G V Q+ ++ T+
Sbjct: 511 GPSGAGKTSLLSALAGKA-VGCKLSGLILINGKQESIHSYKKIIGFVPQDDVVHGNLTVE 569
Query: 522 DNITYAVPQELVNDETRISRAIGQANCTKFLA--NFPDGLQTTVGPRGTQLSGGQKQRIA 579
+N+ + L D ++ + + L L TV RG +SGGQ++R+
Sbjct: 570 ENLWFHAKCRLPADLSKADKVLVVERIIDSLGLQAVRSSLVGTVEKRG--ISGGQRKRVN 627
Query: 580 LARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVS--TIQHSSR 637
+ +++PS+L LDE TS LDS S +++ ++L+ + G + H+ S + +
Sbjct: 628 VGLEMVMEPSVLFLDEPTSGLDSASSQLLLRALRHEALEGVNICMVVHQPSYTLFKTFND 687
Query: 638 VIVLNRHGTVAETGSFDKL 656
+++L + G GS +K+
Sbjct: 688 LVLLAKGGLTVYHGSVNKV 706
>At1g51500 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 687
Score = 74.7 bits (182), Expect = 5e-13
Identities = 62/198 (31%), Positives = 99/198 (49%), Gaps = 14/198 (7%)
Query: 441 PQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL---LRYYDIGSGEIKLGNDNIR-D 496
P + + LN PG + I+GPSG GKST+ L L I +G + L R D
Sbjct: 40 PTRRLLDGLNGHAEPGRIMAIMGPSGSGKSTLLDSLAGRLARNVIMTGNLLLNGKKARLD 99
Query: 497 FNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETR--ISRAIGQANCTKFLAN 554
+ L Y V Q++ ++ + T+ + ITY+ L +D T+ ++ + L +
Sbjct: 100 YGLVAY-----VTQEDILMGTLTVRETITYSAHLRLSSDLTKEEVNDIVEGTIIELGLQD 154
Query: 555 FPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQ 614
D + RG +SGG+++R+++A L P IL LDE TS LDS S V Q+L+
Sbjct: 155 CADRVIGNWHSRG--VSGGERKRVSVALEILTRPQILFLDEPTSGLDSASAFFVIQALRN 212
Query: 615 RSA-RGKTTISIAHRVST 631
+ G+T +S H+ S+
Sbjct: 213 IARDGGRTVVSSIHQPSS 230
>7296045 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 627
Score = 74.7 bits (182), Expect = 5e-13
Identities = 63/239 (26%), Positives = 109/239 (45%), Gaps = 30/239 (12%)
Query: 419 DPVTLENKSIHFNHVKFSYPTRP--QHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL 476
DPV ++ + + KFS+P R I LN + R GE I+GPSG GKST+ +++
Sbjct: 102 DPVDIQFADVRYTVKKFSFPERKFVTKEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVM 161
Query: 477 L----------------------RYYDIG-SGEIKLGNDNIRDFNLRKYRRLLGVVQQEP 513
RY G SG+I++ + + R +R++L + Q+
Sbjct: 162 SGFCNGRGGKDDAPGGTRVFIAKRYRSTGVSGDIRVNRKPMAPSSER-FRQMLCYIHQDD 220
Query: 514 MLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGG 573
+L ++ I + ++++A L+ GL +LSGG
Sbjct: 221 LLRPQLLVGEIMLLAAHLKLG--FKVTKAYKMDLIKHILSLL--GLDHRYNVPTGKLSGG 276
Query: 574 QKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTI 632
QK+R+A+A + +P +L LDE T+ LDS S L++ +++G T + H+ S +
Sbjct: 277 QKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVALLKKLASQGHTIVCTIHQPSAL 335
>At1g51460 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 678
Score = 73.9 bits (180), Expect = 8e-13
Identities = 63/194 (32%), Positives = 98/194 (50%), Gaps = 17/194 (8%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL---LRYYDIGSGEIKLGNDNIR-DFNLR 500
+ +N P + I+GPSG GKST+ L L + SG++ + R DF
Sbjct: 30 LLNGVNGCGEPNRILAIMGPSGSGKSTLLDALAGRLAGNVVMSGKVLVNGKKRRLDFGAA 89
Query: 501 KYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRA-IGQANCTKFLANFPDGL 559
Y V Q++ +L + T+ ++I+Y+ L + TR + I +A T +
Sbjct: 90 AY-----VTQEDVLLGTLTVRESISYSAHLRLPSKLTREEISDIVEATITDM--GLEECS 142
Query: 560 QTTVGP---RGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRS 616
T+G RG +SGG+K+R+++A L PS+L LDE TS LDS S V Q L+ +
Sbjct: 143 DRTIGNWHLRG--ISGGEKKRLSIALEVLTKPSLLFLDEPTSGLDSASAFFVVQILRNIA 200
Query: 617 ARGKTTISIAHRVS 630
+ GKT +S H+ S
Sbjct: 201 SSGKTVVSSIHQPS 214
>CE05669 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 695
Score = 73.2 bits (178), Expect = 1e-12
Identities = 67/222 (30%), Positives = 104/222 (46%), Gaps = 22/222 (9%)
Query: 442 QHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL----LRYYDIGSGEIKLGNDNIRDF 497
+ I + ++ RPGE I+G SG GK+T+ ++L L+ + G+I + N+
Sbjct: 115 RQEILKKIDGVARPGELTFIMGSSGAGKTTLLNILTGRNLKNIET-DGDIMINGRNMISN 173
Query: 498 NLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKF------ 551
++K L VQQ+ + F GT+ T +L R A+G
Sbjct: 174 EMKK---LSAYVQQDDV-FIGTLTVRETLRFAAKL-----RSPSALGATELDSIVDELLV 224
Query: 552 LANFPDGLQTTVGPRGTQ-LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQ 610
+ + T VG + LS G+++R+A A L DP IL DE TS LDS V +
Sbjct: 225 MMSLKKCENTKVGTMTEKSLSRGERKRLAFACEILTDPPILFCDEPTSGLDSFMSHQVIK 284
Query: 611 SLQQRSARGKTTISIAHRVST-IQHSSRVIVLNRHGTVAETG 651
+L+Q + GKT I H+ ST + H + ++L G VA G
Sbjct: 285 ALRQLTIEGKTVICTIHQPSTSVYHMADQLILLSQGHVAYAG 326
>7295722 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 832
Score = 72.8 bits (177), Expect = 2e-12
Identities = 51/188 (27%), Positives = 97/188 (51%), Gaps = 10/188 (5%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG-SGEIKLGNDNIRDFNLRKYR 503
I + ++ R GE I+GPSG GKST+ ++L Y SG + + N ++ NLR++R
Sbjct: 165 ILKSVSGKFRNGEITAIMGPSGAGKSTLMNILAGYKTAQLSGSVLI---NSKERNLRRFR 221
Query: 504 RLLGVVQQEPMLFSG-TILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTT 562
+L + Q+ +L + T+ + + A +L + ++ + + + GL+ +
Sbjct: 222 KLSCYIMQDDVLIANLTVREAMMVAANLKLGKNMISYAKVVVVEEILETI-----GLKES 276
Query: 563 VGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTT 622
V LSGGQ++R+++A + +P ++ DE TS LDS + + L+ + G+T
Sbjct: 277 VNTLTCNLSGGQRKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQLISLLRSLARGGRTI 336
Query: 623 ISIAHRVS 630
+ H+ S
Sbjct: 337 VCTIHQPS 344
>At3g13220 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 647
Score = 72.4 bits (176), Expect = 2e-12
Identities = 65/241 (26%), Positives = 116/241 (47%), Gaps = 32/241 (13%)
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLL-RYYDIGSGEIKLGNDNIRDFNLRKY 502
HI + + + PGE + ++GPSG GK+T+ ++ R D G++ N ++
Sbjct: 67 HILKGITGSTGPGEILALMGPSGSGKTTLLKIMGGRLTDNVKGKLTY---NDIPYSPSVK 123
Query: 503 RRLLGVVQQEPMLFSGTILDNITYA----VPQELVNDET-----RISRAIGQANCTKFLA 553
RR+ V Q + +L T+ + + +A +P + ++ I + +G C +
Sbjct: 124 RRIGFVTQDDVLLPQLTVEETLAFAAFLRLPSSMSKEQKYAKIEMIIKELGLERCRR--- 180
Query: 554 NFPDGLQTTVGPRGTQ-LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSL 612
T VG + +SGG+++R ++A L+DPS+L+LDE TS LDS S + L
Sbjct: 181 -------TRVGGGFVKGISGGERKRASIAYEILVDPSLLLLDEPTSGLDSTSATKLLHIL 233
Query: 613 QQRSARGKTTISIAHRVST-IQHSSRVIVLNRHGTVAETGS-------FDKLIAIPDSSL 664
Q + G+T I+ H+ S+ + H ++L G A G F L +P+ ++
Sbjct: 234 QGVAKAGRTVITTIHQPSSRMFHMFDKLLLISEGHPAFYGKARESMEYFSSLRILPEIAM 293
Query: 665 N 665
N
Sbjct: 294 N 294
>At1g17840 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 692
Score = 72.4 bits (176), Expect = 2e-12
Identities = 62/201 (30%), Positives = 96/201 (46%), Gaps = 27/201 (13%)
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL---LRYYDIGSGEIKL-GNDNIRDFNL 499
++ E L PG ++GPSG GKST+ L L SG + L G F
Sbjct: 68 NVLEGLTGYAEPGSLTALMGPSGSGKSTMLDALASRLAANAFLSGTVLLNGRKTKLSFGT 127
Query: 500 RKYRRLLGVVQQEPMLFSGTILDNITYA----VPQELVNDETR--ISRAIGQANCTKFLA 553
Y V Q + ++ + T+ + I Y+ +P +++ E R + R I +
Sbjct: 128 AAY-----VTQDDNLIGTLTVRETIWYSARVRLPDKMLRSEKRALVERTIIEMG------ 176
Query: 554 NFPDGLQTTVGP---RGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQ 610
D T +G RG +SGG+K+R+++A L+ P +L LDE TS LDS S V Q
Sbjct: 177 -LQDCADTVIGNWHLRG--ISGGEKRRVSIALEILMRPRLLFLDEPTSGLDSASAFFVTQ 233
Query: 611 SLQQRSARGKTTISIAHRVST 631
+L+ S G+T I+ H+ S+
Sbjct: 234 TLRALSRDGRTVIASIHQPSS 254
>Hs8051577 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 662
Score = 71.6 bits (174), Expect = 4e-12
Identities = 57/210 (27%), Positives = 95/210 (45%), Gaps = 14/210 (6%)
Query: 427 SIHFNHVKFSYPTRPQHH------IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYY 480
+I F + +S P P + + ++ GE V I+GPSG GKST+ ++L Y
Sbjct: 72 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 131
Query: 481 DIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRIS 540
+ G L N RD LR +R++ + Q+ ML + + ++
Sbjct: 132 ETGMKGAVLINGLPRD--LRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGR 189
Query: 541 RAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSAL 600
R + + T GL + R LSGGQ++R+A+A + +P ++ DE TS L
Sbjct: 190 REMVKEILTAL------GLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGL 243
Query: 601 DSQSEEVVAQSLQQRSARGKTTISIAHRVS 630
DS S V ++ + G++ I H+ S
Sbjct: 244 DSASCFQVVSLMKGLAQGGRSIICTIHQPS 273
>Hs8051575 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 674
Score = 71.6 bits (174), Expect = 4e-12
Identities = 57/210 (27%), Positives = 95/210 (45%), Gaps = 14/210 (6%)
Query: 427 SIHFNHVKFSYPTRPQHH------IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYY 480
+I F + +S P P + + ++ GE V I+GPSG GKST+ ++L Y
Sbjct: 72 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 131
Query: 481 DIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRIS 540
+ G L N RD LR +R++ + Q+ ML + + ++
Sbjct: 132 ETGMKGAVLINGLPRD--LRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGR 189
Query: 541 RAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSAL 600
R + + T GL + R LSGGQ++R+A+A + +P ++ DE TS L
Sbjct: 190 REMVKEILTAL------GLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGL 243
Query: 601 DSQSEEVVAQSLQQRSARGKTTISIAHRVS 630
DS S V ++ + G++ I H+ S
Sbjct: 244 DSASCFQVVSLMKGLAQGGRSIICTIHQPS 273
>CE28537 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 610
Score = 71.6 bits (174), Expect = 4e-12
Identities = 69/222 (31%), Positives = 104/222 (46%), Gaps = 25/222 (11%)
Query: 419 DPVTL--ENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL 476
DPVTL N SIH + I E+++ +PG+ + ++G SG GK+T+ ++L
Sbjct: 30 DPVTLTWHNISIHAE--------KSGKQILENVSGIAKPGQLLALMGASGAGKTTLLNML 81
Query: 477 LRYYDIG---SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQEL- 532
L G SG +K+ + R + G QQ+ LF GT+ + +L
Sbjct: 82 LSRNLRGLETSGSVKVNGHELG----RGITAISGYAQQDE-LFVGTLTVKEYLDIQAKLR 136
Query: 533 VN-DETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQ--LSGGQKQRIALARAFLLDPS 589
VN D + R +G L + T +G G Q +SGG+ +R+ A L +PS
Sbjct: 137 VNGDSEKRRRRVGNVMSQLGLYKCQN---TRIGTIGGQKGISGGEMRRLTFACELLSNPS 193
Query: 590 ILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVST 631
IL DE T+ LDS E V Q L + G+T I H+ S+
Sbjct: 194 ILFCDEPTTGLDSFMAESVVQVLSNLAKSGRTVICTIHQPSS 235
>At3g55100 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 662
Score = 71.6 bits (174), Expect = 4e-12
Identities = 66/235 (28%), Positives = 110/235 (46%), Gaps = 28/235 (11%)
Query: 421 VTLENK-SIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRY 479
VTL+ + + F H T + + + GE + I+G SG GKST+ L
Sbjct: 31 VTLQQRFGLRFGHSPAKIKT-----LLNGITGEAKEGEILAILGASGAGKSTLIDALAGQ 85
Query: 480 YDIGS--GEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSG-TILDNITYAVPQELVNDE 536
GS G + L + ++ R R + V QE +LF T+ + + +A E
Sbjct: 86 IAEGSLKGTVTLNGEALQS---RLLRVISAYVMQEDLLFPMLTVEETLMFAA-------E 135
Query: 537 TRISRAIGQANCTKFLANFPDGL------QTTVGPRGTQ-LSGGQKQRIALARAFLLDPS 589
R+ R++ ++ + D L T +G G + +SGG+++R+++ + DP
Sbjct: 136 FRLPRSLSKSKKRNRVETLIDQLGLTTVKNTVIGDEGHRGVSGGERRRVSIGTDIIHDPI 195
Query: 590 ILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVS--TIQHSSRVIVLN 642
+L LDE TS LDS S +V Q L++ + G I H+ S ++ RVIVL+
Sbjct: 196 VLFLDEPTSGLDSTSAFMVVQVLKKIARSGSIVIMSIHQPSGRIMEFLDRVIVLS 250
>7295821 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 729
Score = 71.2 bits (173), Expect = 5e-12
Identities = 66/227 (29%), Positives = 106/227 (46%), Gaps = 25/227 (11%)
Query: 442 QHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRK 501
+ I D++ V P E + I+GPSG GK+T+ L I SG + L + + +K
Sbjct: 76 ERQILSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQRHIDSGSVFLNREPLT----KK 131
Query: 502 YRRLLGVVQQEPMLFSG-TILDNITYA----VPQELVNDET-----RISRAIGQANCTKF 551
+RR +G V QE + F T+ + + Y +P+ + E I A+ C +
Sbjct: 132 WRRRIGYVLQEEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQVDHILEALELGCCQQ- 190
Query: 552 LANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQS 611
F D L RG LSGG+K+R +A L +P +++LDE TS LDS S + +
Sbjct: 191 -TKFGDYLN-----RG--LSGGEKKRANIACELLTNPLLMLLDEPTSGLDSHSAISLMKV 242
Query: 612 LQQRSARGKTT--ISIAHRVSTIQHSSRVIVLNRHGTVAETGSFDKL 656
L++ + + T IS+ S + H ++L G A G +
Sbjct: 243 LKRYAQLEQKTIVISVHQPSSQMFHMFDKLLLLHQGRTAYFGDVQNI 289
>Hs20143975 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 646
Score = 70.9 bits (172), Expect = 6e-12
Identities = 79/275 (28%), Positives = 123/275 (44%), Gaps = 66/275 (24%)
Query: 395 GAGAAARVFELNDRKPLIHPTIGKDP--VTLENKSIHFNHV----KFSY-PTRPQHHI-F 446
G GA A L D G +P +T K + NH+ +FS+ P R I F
Sbjct: 14 GPGAVAMAVTLED---------GAEPPVLTTHLKKVE-NHITEAQRFSHLPKRSAVDIEF 63
Query: 447 EDLNFTVRPG----------------------EHVCIVGPSGGGKSTVASLLLRYYDIG- 483
+L+++VR G E + I+GPSG GKST ++L Y + G
Sbjct: 64 VELSYSVREGPCWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGM 123
Query: 484 SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSG-TILD------NITYAVPQELVND- 535
G+I + N R LR +R++ + Q+ ML T+L+ N+ + QE+ +
Sbjct: 124 KGQILV---NGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQEVKKEL 180
Query: 536 ETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDE 595
T I A+G +C+ R LSGGQ++R+A+A + +P ++ DE
Sbjct: 181 VTEILTALGLMSCSH--------------TRTALLSGGQRKRLAIALELVNNPPVMFFDE 226
Query: 596 ATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVS 630
TS LDS S V ++ + G+T I H+ S
Sbjct: 227 PTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPS 261
>CE09192 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 658
Score = 70.9 bits (172), Expect = 6e-12
Identities = 59/213 (27%), Positives = 97/213 (44%), Gaps = 20/213 (9%)
Query: 455 PGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPM 514
PGE + ++G SG GK+T+ ++L G + N + +K R++ VQQ
Sbjct: 85 PGEVLALMGGSGAGKTTLMNILAHLDTNGVEYLGDVTVNGKKITKQKMRQMCAYVQQVD- 143
Query: 515 LFSGTIL--DNITY--------AVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
LF GT+ + +TY A Q+ + + R + +C L P+ ++
Sbjct: 144 LFCGTLTVREQLTYTAHMRMKNATVQQKMERVENVLRDMNLTDCQNTLIGIPNRMKG--- 200
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
+S G+K+R+A A L DP IL DE TS LD+ V ++L + +GKT I
Sbjct: 201 -----ISIGEKKRLAFACEILTDPKILFCDEPTSGLDAFMASEVVRALLDLANKGKTIIV 255
Query: 625 IAHR-VSTIQHSSRVIVLNRHGTVAETGSFDKL 656
+ H+ ST+ + G G+ D+L
Sbjct: 256 VLHQPSSTVFRMFHKVCFMATGKTVYHGAVDRL 288
>At3g52310 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 737
Score = 70.9 bits (172), Expect = 6e-12
Identities = 60/241 (24%), Positives = 114/241 (46%), Gaps = 33/241 (13%)
Query: 420 PVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL--- 476
P+ L+ I + + + I ++ + PGE + ++GPSG GK+T+ + L
Sbjct: 142 PIYLKFIDITYKVTTKGMTSSSEKSILNGISGSAYPGELLALMGPSGSGKTTLLNALGGR 201
Query: 477 LRYYDIGSGEIKLGNDNIRDFNLRKYRRL-LGVVQQEPMLFSG-TILDNITYA----VPQ 530
+IG G+ + D K+ + +G V Q+ +LF T+ + +TY +P+
Sbjct: 202 FNQQNIG------GSVSYNDKPYSKHLKTRIGFVTQDDVLFPHLTVKETLTYTALLRLPK 255
Query: 531 ELVNDETR-----ISRAIGQANCTKFLANFPDGLQTTVGPRGTQ-LSGGQKQRIALARAF 584
L E + + +G C T +G + +SGG+++R+ +
Sbjct: 256 TLTEQEKEQRAASVIQELGLERCQ----------DTMIGGSFVRGVSGGERKRVCIGNEI 305
Query: 585 LLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVST--IQHSSRVIVLN 642
+ +PS+L+LDE TS+LDS + + Q L + GKT ++ H+ S+ +++VL+
Sbjct: 306 MTNPSLLLLDEPTSSLDSTTALKIVQMLHCIAKAGKTIVTTIHQPSSRLFHRFDKLVVLS 365
Query: 643 R 643
R
Sbjct: 366 R 366
>CE02547 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 661
Score = 70.5 bits (171), Expect = 8e-12
Identities = 113/543 (20%), Positives = 212/543 (38%), Gaps = 57/543 (10%)
Query: 142 MIFGLTSTQFYTALGGVFVVGALANVGRIVILKVTGERLVARLRTRTMKAALEQDATFLD 201
++F L + ++ L + V A+ G + ERL L ++ +K + LD
Sbjct: 123 LLFALEAFKYVLNLPAISVTNAILKFGIAELKLRFRERLSTHLYSQYLKGFTFYKMSNLD 182
Query: 202 HNRVGDLISRLSSDAGIVSKSVTQNLSDGTRAVIQGFVG-FGMMSFISWKLTCVMMLLAP 260
R+ + L+ D + + S+ ++ ++ F+ F + + + + ++
Sbjct: 183 -TRIQNADQLLTQDVDRFCDGIVELYSNLSKPILDVFLYLFRLGTSLGFSSPSILFSYLL 241
Query: 261 PLGVMALVYGKRIRNLSRQLQTSVGELTKVSEEQLSATKTIQAYCGEKKE-------IHR 313
GV + I L+ + Q GE V+ + ++ I Y G + E
Sbjct: 242 FTGVGLTYLRRPIGRLTVEEQALEGEYRYVNSRLIMNSEEIAFYQGNQSEKETIMSTFAS 301
Query: 314 YADEVRKV----FHVGLKEALTSGAFFGVTGF--VGNVALLALLLTGTSMIKTGLMTVGD 367
+RK+ F +G + + + V G+ VG+ M + LM
Sbjct: 302 LVQHLRKIILFRFSIGFVDNIVAKYLATVVGWYAVGSSFFDKQHKPFIGMSRNQLMQEYY 361
Query: 368 LSSFMMYAVXXXXXXXXXXXXXXELMKG----------------AGAAAR--VFELNDRK 409
S MMY + + G +G R V E +
Sbjct: 362 NSGRMMYKMAEALGRLALAGRDMTRLSGFTSRVDTLLNVLDDVNSGNYKRTMVGEKEESS 421
Query: 410 PLIHPTI--GKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGG 467
LI + G + +++ I F++V P + E LNF V G +V + GP+G
Sbjct: 422 ALIKSELVAGSGNLRVQDNVIRFDNVPLVTPNGDV--LIERLNFEVPSGTNVLVCGPNGC 479
Query: 468 GKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYA 527
GKS++ +L + + G + + + L V Q P + GT+ D I Y
Sbjct: 480 GKSSLFRVLGELWPLFGGTLT-----------KPAKGKLFYVPQRPYMTLGTLRDQIIYP 528
Query: 528 V-PQELVN---DETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARA 583
P +++ ++ + + + T L +G + V LSGG+KQRIA+AR
Sbjct: 529 DRPLDMIRKGVSDSDLEQMLENVQLTHILER--EGGWSAVQDWMDVLSGGEKQRIAMARL 586
Query: 584 FLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNR 643
F P ILDE TSA+ E + + ++++ T +++HR S ++ + ++
Sbjct: 587 FYHKPQFAILDECTSAVSVDVEGAMYRLCREKNI---TLFTVSHRKSLWKYHEYSLYMDG 643
Query: 644 HGT 646
G+
Sbjct: 644 RGS 646
>YOL075c [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-15) ABC
superfamily
Length = 1294
Score = 70.1 bits (170), Expect = 1e-11
Identities = 65/241 (26%), Positives = 111/241 (45%), Gaps = 38/241 (15%)
Query: 443 HH----IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL--------LRYYDIGSGEIKLG 490
HH I + +N +PG I+GPSG GKS++ +L+ +D SG I
Sbjct: 703 HHETKEILQSVNAIFKPGMINAIMGPSGSGKSSLLNLISGRLKSSVFAKFDT-SGSIMFN 761
Query: 491 NDNIRDFNLRKYRRLLGVVQQEP--MLFSGTILDNITYAVPQEL--------VNDETRIS 540
+ + + ++ + V Q+ +L + T+ + + YA L + +
Sbjct: 762 DIQVSEL---MFKNVCSYVSQDDDHLLAALTVKETLKYAAALRLHHLTEAERMERTDNLI 818
Query: 541 RAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSAL 600
R++G +C + G + G +SGG+K+R+ + L DP IL+LDE TS L
Sbjct: 819 RSLGLKHCENNII----GNEFVKG-----ISGGEKRRVTMGVQLLNDPPILLLDEPTSGL 869
Query: 601 DSQSEEVVAQSLQQR-SARGKTTISIAH--RVSTIQHSSRVIVLNRHGTVAETGSFDKLI 657
DS + + + L++ +GKT I H R + V++L + G A GS D++I
Sbjct: 870 DSFTSATILEILEKLCREQGKTIIITIHQPRSELFKRFGNVLLLAKSGRTAFNGSPDEMI 929
Query: 658 A 658
A
Sbjct: 930 A 930
Score = 52.4 bits (124), Expect = 2e-06
Identities = 51/193 (26%), Positives = 94/193 (48%), Gaps = 22/193 (11%)
Query: 456 GEHVCIVGPSGGGKSTVASLL-------------LRYY--DIGSG----EIKLGNDNIRD 496
G + ++G SG GK+T+ ++L +RY D GS E K + + +D
Sbjct: 55 GSVMAVMGGSGSGKTTLLNVLASKISGGLTHNGSIRYVLEDTGSEPNETEPKRAHLDGQD 114
Query: 497 FNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFP 556
++K+ + + QQ+ + T + + +A +L + E + Q L +
Sbjct: 115 HPIQKHVIMAYLPQQDVLSPRLTCRETLKFAADLKLNSSERTKKLMVEQLIEELGLKDCA 174
Query: 557 DGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRS 616
D L RG LSGG+K+R+++ + +PSI+ LDE T+ LD+ S +V ++L++ +
Sbjct: 175 DTLVGDNSHRG--LSGGEKRRLSIGTQMISNPSIMFLDEPTTGLDAYSAFLVIKTLKKLA 232
Query: 617 AR-GKTTISIAHR 628
G+T I H+
Sbjct: 233 KEDGRTFIMSIHQ 245
>Hs4757850 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 655
Score = 70.1 bits (170), Expect = 1e-11
Identities = 58/195 (29%), Positives = 100/195 (50%), Gaps = 18/195 (9%)
Query: 442 QHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG--SGEIKLGNDNIRDFNL 499
+ I ++N ++PG + I+GP+GGGKS++ +L D SG++ + N R N
Sbjct: 60 EKEILSNINGIMKPGLNA-ILGPTGGGKSSLLDVLAARKDPSGLSGDVLI-NGAPRPANF 117
Query: 500 RKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDET------RISRAIGQANCTKFLA 553
+ VVQ + ++ + T+ +N+ ++ L T RI+R I + K +A
Sbjct: 118 KCNSGY--VVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIEELGLDK-VA 174
Query: 554 NFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQ 613
+ G Q G +SGG+++R ++ + DPSIL LDE T+ LDS + V L+
Sbjct: 175 DSKVGTQFIRG-----VSGGERKRTSIGMELITDPSILSLDEPTTGLDSSTANAVLLLLK 229
Query: 614 QRSARGKTTISIAHR 628
+ S +G+T I H+
Sbjct: 230 RMSKQGRTIIFSIHQ 244
>At2g13610 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 649
Score = 70.1 bits (170), Expect = 1e-11
Identities = 59/219 (26%), Positives = 109/219 (48%), Gaps = 14/219 (6%)
Query: 444 HIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYR 503
H+ + + +P E + IVGPSG GKS++ +L +G + + N R + ++
Sbjct: 61 HVLKGVTCRAKPWEILAIVGPSGAGKSSLLEILAARLIPQTGSVYV---NKRPVDRANFK 117
Query: 504 RLLGVVQQEPMLFSG-TILDNITYAVPQ--ELVNDETRIS-RAIGQANCTKFLANFPDGL 559
++ G V Q+ LF T+ + + ++ +L DE R +++ + +A G
Sbjct: 118 KISGYVTQKDTLFPLLTVEETLLFSAKLRLKLPADELRSRVKSLVHELGLEAVATARVGD 177
Query: 560 QTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRS-AR 618
+ G +SGG+++R+++ + DP +LILDE TS LDS S ++ L+ + R
Sbjct: 178 DSVRG-----ISGGERRRVSIGVEVIHDPKVLILDEPTSGLDSTSALLIIDMLKHMAETR 232
Query: 619 GKTTISIAHRVS-TIQHSSRVIVLNRHGTVAETGSFDKL 656
G+T I H+ I ++L +G+ + GS D+L
Sbjct: 233 GRTIILTIHQPGFRIVKQFNSVLLLANGSTLKQGSVDQL 271
>At5g19410 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 624
Score = 69.7 bits (169), Expect = 1e-11
Identities = 69/260 (26%), Positives = 120/260 (45%), Gaps = 38/260 (14%)
Query: 414 PTIGKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVA 473
PT + +T+ N S NH I ++ + + +VGPSG GKST+
Sbjct: 45 PTPNRYSLTVTNLSYTINHTP----------ILNSVSLAAESSKILAVVGPSGTGKSTLL 94
Query: 474 SLLLRYYDIG----SGEIKLGNDNIRDFNLRKYRRLLGVVQQE----PMLFSGTILDNIT 525
++ + S + + N I D+N + RRL G V Q+ P+L T+ + +
Sbjct: 95 KIISGRVNHKALDPSSAVLMNNRKITDYN--QLRRLCGFVPQDDDLLPLL---TVKETLM 149
Query: 526 YAVPQELVND-----ETRISRAIGQANCTKFLANFP-DGLQTTVGPRGTQLSGGQKQRIA 579
Y+ L + E R+ + +F +G + G +SGG+++R++
Sbjct: 150 YSAKFSLRDSTAKEREERVESLLSDLGLVLVQDSFVGEGDEEDRG-----VSGGERKRVS 204
Query: 580 LARAFLLDPSILILDEATSALDSQ-SEEVVAQSLQQRSARGKTTISIAHRVS--TIQHSS 636
+A + DP IL+LDE TS LDS+ S +VV ++ +T + H+ S + + S
Sbjct: 205 IAVEMIRDPPILLLDEPTSGLDSRNSLQVVELLATMAKSKQRTVLFSIHQPSYRILDYIS 264
Query: 637 RVIVLNRHGTVAETGSFDKL 656
++L+R G+V GS + L
Sbjct: 265 DYLILSR-GSVIHLGSLEHL 283
>At5g09930 [R] KOG0927 Predicted transporter (ABC superfamily)
Length = 674
Score = 69.7 bits (169), Expect = 1e-11
Identities = 58/211 (27%), Positives = 101/211 (47%), Gaps = 24/211 (11%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+F N + GE V I+GP+G GKST+ L++ GE+ LG N+ L Y
Sbjct: 421 LFNKANLAIERGEKVAIIGPNGCGKSTLLKLIMGLEKPMRGEVILGEHNV----LPNY-- 474
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
Q E T+++ + A ++D I +G+ N F A+ D
Sbjct: 475 -FEQNQAEAQDLDKTVIETVVEAAVDWRIDD---IKALLGRCN---FKADMLD------- 520
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
+ + LSGG+K R+A + + ++L+LDE T+ LD S+E++ +++ + T I+
Sbjct: 521 RKVSLLSGGEKARLAFCKFMVKPSTLLVLDEPTNHLDIPSKEMLEEAINEYKG---TVIT 577
Query: 625 IAH-RVSTIQHSSRVIVLNRHGTVAETGSFD 654
++H R Q +RVI + G + G ++
Sbjct: 578 VSHDRYFIKQIVNRVIEVRDGGLMDYAGDYN 608
>At3g55130 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 725
Score = 69.7 bits (169), Expect = 1e-11
Identities = 57/215 (26%), Positives = 106/215 (48%), Gaps = 21/215 (9%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGS--GEIKLGNDNIRDFNLRKY 502
+ +D++ G+ + ++G SG GKST+ L GS G + L + + L K
Sbjct: 99 LLDDVSGEASDGDILAVLGASGAGKSTLIDALAGRVAEGSLRGSVTLNGEKVLQSRLLKV 158
Query: 503 RRLLGVVQQEPMLFSG-TILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGL-- 559
+ V Q+ +LF T+ + + +A E R+ R++ ++ + + D L
Sbjct: 159 --ISAYVMQDDLLFPMLTVKETLMFA-------SEFRLPRSLSKSKKMERVEALIDQLGL 209
Query: 560 ----QTTVGPRGTQ-LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQ 614
T +G G + +SGG+++R+++ + DP +L LDE TS LDS + +V Q L++
Sbjct: 210 RNAANTVIGDEGHRGVSGGERRRVSIGIDIIHDPIVLFLDEPTSGLDSTNAFMVVQVLKR 269
Query: 615 RSARGKTTISIAHRVST--IQHSSRVIVLNRHGTV 647
+ G I H+ S ++ R+I+L+R +V
Sbjct: 270 IAQSGSIVIMSIHQPSARIVELLDRLIILSRGKSV 304
>At3g55110 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 708
Score = 69.3 bits (168), Expect = 2e-11
Identities = 61/220 (27%), Positives = 105/220 (47%), Gaps = 22/220 (10%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYY--DIGSGEIKLGNDNIRDFNLRKY 502
+ +D+ R GE + ++G SG GKST+ L D G + L + + L K
Sbjct: 91 LLDDITGEARDGEILAVLGGSGAGKSTLIDALAGRVAEDSLKGTVTLNGEKVLQSRLLKV 150
Query: 503 RRLLGVVQQEPMLFSG-TILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGL-- 559
+ V Q+ +LF T+ + + +A E R+ R++ ++ + + D L
Sbjct: 151 --ISAYVMQDDLLFPMLTVKETLMFA-------SEFRLPRSLPKSKKMERVETLIDQLGL 201
Query: 560 ----QTTVGPRGTQ-LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQ 614
T +G G + +SGG+++R+++ + DP +L LDE TS LDS + +V Q L++
Sbjct: 202 RNAADTVIGDEGHRGVSGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTNAFMVVQVLKR 261
Query: 615 RSARGKTTISIAHRVST--IQHSSRVIVLNRHGTVAETGS 652
+ G I H+ S I R+I+L+ HG GS
Sbjct: 262 IAQSGSVVIMSIHQPSARIIGLLDRLIILS-HGKSVFNGS 300
>At2g39350 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 740
Score = 69.3 bits (168), Expect = 2e-11
Identities = 58/215 (26%), Positives = 103/215 (46%), Gaps = 22/215 (10%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGS--GEIKLGNDNIRDFNLRKY 502
+ +++ R GE + ++G SG GKST+ L GS G +KL + ++ R
Sbjct: 109 LLNNISGETRDGEIMAVLGASGSGKSTLIDALANRIAKGSLKGTVKLNGETLQS---RML 165
Query: 503 RRLLGVVQQEPMLF-----SGTILDNITYAVPQELVNDET--RISRAIGQANCTKFLANF 555
+ + V Q+ +LF T++ + +P+ L + R+ I Q
Sbjct: 166 KVISAYVMQDDLLFPMLTVEETLMFAAEFRLPRSLPKSKKKLRVQALIDQLGIR------ 219
Query: 556 PDGLQTTVGPRGTQ-LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQ 614
+ +T +G G + +SGG+++R+++ + DP +L LDE TS LDS S +V + L++
Sbjct: 220 -NAAKTIIGDEGHRGISGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTSAFMVVKVLKR 278
Query: 615 RSARGKTTISIAHRVS--TIQHSSRVIVLNRHGTV 647
+ G I H+ S + R+I L+R TV
Sbjct: 279 IAQSGSIVIMSIHQPSHRVLGLLDRLIFLSRGHTV 313
>7297581 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 689
Score = 69.3 bits (168), Expect = 2e-11
Identities = 71/249 (28%), Positives = 119/249 (47%), Gaps = 25/249 (10%)
Query: 418 KDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLL 477
++PV +E K + VK + R I ++ + + I+GPSG GKST+ L
Sbjct: 100 REPVDMEFKELSLT-VKLGF-NRGSKEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDALS 157
Query: 478 RYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQE----PMLFSGTILDNITYAVPQEL- 532
+ G L N RD L +RR+ + Q+ P+L T+ +N+ A +L
Sbjct: 158 GFKTTGVDGSILLNGRRRD--LPSFRRMSCYITQDDRLQPLL---TVNENMHIAADLKLG 212
Query: 533 --VNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSI 590
V+ E + SR + L + T+ +LSGGQK+R+++A + +P++
Sbjct: 213 QTVSYEEKESRI---EDILLLLGLYNHDQTLTM-----RLSGGQKKRLSIAMELINNPTV 264
Query: 591 LILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHR--VSTIQHSSRVIVLNRHGTVA 648
+ LDE T+ LDS S V + L++ +++G+T I H+ Q +V VL+ G
Sbjct: 265 MFLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIHQPTAKLFQIFDQVYVLSA-GNCV 323
Query: 649 ETGSFDKLI 657
GS KL+
Sbjct: 324 YQGSTQKLV 332
>At1g54350 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 680
Score = 68.9 bits (167), Expect = 2e-11
Identities = 56/206 (27%), Positives = 98/206 (47%), Gaps = 14/206 (6%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKY-- 502
+ +L+ V +H+ I+GPSG GK+++ + + G G+I D DF K
Sbjct: 446 LVHNLSADVYDKDHLLIMGPSGSGKTSLLRAMAGLWRSGKGKITFYLDPEVDFTQEKSDT 505
Query: 503 ------RRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFP 556
R + + Q P + G++ + Y P T + C +A+
Sbjct: 506 QENSGKRGDVLFLPQRPYMVLGSLRQQLLY--PTWSATPTTDDLMRTLEKVCLGHIADRF 563
Query: 557 DGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRS 616
GL + + + LS G++QR+A AR L P + +LDE+TSALD +E + Q +Q
Sbjct: 564 GGLDS-IHEWSSVLSLGEQQRLAFARLLLSQPKLALLDESTSALDEANEAFLYQQIQ--- 619
Query: 617 ARGKTTISIAHRVSTIQHSSRVIVLN 642
+ G T ISI HR + + ++++ ++
Sbjct: 620 SAGITYISIGHRRTLTKFHNKILQIS 645
>7294101 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 666
Score = 68.9 bits (167), Expect = 2e-11
Identities = 60/209 (28%), Positives = 104/209 (49%), Gaps = 16/209 (7%)
Query: 453 VRPGEHVCIVGPSGGGKSTVASLLLRYYDIGS---GEIKLGNDNIRDFNLRKYRRLLGVV 509
++PG + ++G SG GK+T+ S L G+ G+I + I F R+ G V
Sbjct: 98 IQPGTLMALMGSSGSGKTTLMSTLAFRQPAGTVVQGDILINGRRIGPF----MHRISGYV 153
Query: 510 QQEPM-LFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFL--ANFPDGLQTTVGPR 566
Q+ + L S T+L+++ + L + R+S+ + + L QT +G
Sbjct: 154 YQDDLFLGSLTVLEHLNFMAHLRL---DRRVSKEERRLIIKELLERTGLLSAAQTRIGSG 210
Query: 567 GTQ--LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
+ LSGG+++R+A A L +P IL DE T+ LDS S + + +L + + +G T +
Sbjct: 211 DDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTTILC 270
Query: 625 IAHRVST-IQHSSRVIVLNRHGTVAETGS 652
H+ S+ + + ++L G VA TGS
Sbjct: 271 TIHQPSSQLFDNFNNVMLLADGRVAFTGS 299
>Hs4826958 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 606
Score = 68.6 bits (166), Expect = 3e-11
Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 17/202 (8%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+ +DL+ + G+ + I G +G GK+++ +L + G +++ + DF
Sbjct: 403 LIKDLSLKISEGQSLLITGNTGTGKTSLLRVLGGLWTSTRGSVQM----LTDFGPHGVLF 458
Query: 505 LLGVVQQEPMLFSGTILDNITYAV----PQELVNDETRISRAIGQANCTKFLANFPDGLQ 560
L Q+P GT+ + + Y + P D+ RI R + A + +A +GL
Sbjct: 459 L----PQKPFFTDGTLREQVIYPLKEVYPDSGSADDERILRFLELAGLSNLVAR-TEGLD 513
Query: 561 TTVGPRGTQ-LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARG 619
V LS G+ QR++ AR F L P +LDEATSAL +EEV ++ + G
Sbjct: 514 QQVDWNWYDVLSPGEMQRLSFARLFYLQPKYAVLDEATSAL---TEEVESELYRIGQQLG 570
Query: 620 KTTISIAHRVSTIQHSSRVIVL 641
T IS+ HR S + S V+ L
Sbjct: 571 MTFISVGHRQSLEKFHSLVLKL 592
>Hs10947129 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 447
Score = 68.6 bits (166), Expect = 3e-11
Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 17/202 (8%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+ +DL+ + G+ + I G +G GK+++ +L + G +++ + DF
Sbjct: 244 LIKDLSLKISEGQSLLITGNTGTGKTSLLRVLGGLWTSTRGSVQM----LTDFGPHGVLF 299
Query: 505 LLGVVQQEPMLFSGTILDNITYAV----PQELVNDETRISRAIGQANCTKFLANFPDGLQ 560
L Q+P GT+ + + Y + P D+ RI R + A + +A +GL
Sbjct: 300 L----PQKPFFTDGTLREQVIYPLKEVYPDSGSADDERILRFLELAGLSNLVAR-TEGLD 354
Query: 561 TTVGPRGTQ-LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARG 619
V LS G+ QR++ AR F L P +LDEATSAL +EEV ++ + G
Sbjct: 355 QQVDWNWYDVLSPGEMQRLSFARLFYLQPKYAVLDEATSAL---TEEVESELYRIGQQLG 411
Query: 620 KTTISIAHRVSTIQHSSRVIVL 641
T IS+ HR S + S V+ L
Sbjct: 412 MTFISVGHRQSLEKFHSLVLKL 433
>Hs10947127 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 563
Score = 68.6 bits (166), Expect = 3e-11
Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 17/202 (8%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+ +DL+ + G+ + I G +G GK+++ +L + G +++ + DF
Sbjct: 360 LIKDLSLKISEGQSLLITGNTGTGKTSLLRVLGGLWTSTRGSVQM----LTDFGPHGVLF 415
Query: 505 LLGVVQQEPMLFSGTILDNITYAV----PQELVNDETRISRAIGQANCTKFLANFPDGLQ 560
L Q+P GT+ + + Y + P D+ RI R + A + +A +GL
Sbjct: 416 L----PQKPFFTDGTLREQVIYPLKEVYPDSGSADDERILRFLELAGLSNLVAR-TEGLD 470
Query: 561 TTVGPRGTQ-LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARG 619
V LS G+ QR++ AR F L P +LDEATSAL +EEV ++ + G
Sbjct: 471 QQVDWNWYDVLSPGEMQRLSFARLFYLQPKYAVLDEATSAL---TEEVESELYRIGQQLG 527
Query: 620 KTTISIAHRVSTIQHSSRVIVL 641
T IS+ HR S + S V+ L
Sbjct: 528 MTFISVGHRQSLEKFHSLVLKL 549
>CE05518 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 660
Score = 68.2 bits (165), Expect = 4e-11
Identities = 67/224 (29%), Positives = 103/224 (45%), Gaps = 17/224 (7%)
Query: 427 SIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGE 486
+I + S P H I + L+ + G+ + I G SG GKS++ + + SG+
Sbjct: 421 AITVDSATLSPPNDHSHLIVQLLSLQIIQGQTLLITGDSGCGKSSLLRMFAGLWHCSSGK 480
Query: 487 IKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSG--TILDNITYAVPQELVN-DETRISRAI 543
+ D + R+ L + Q+P SG T+ I Y V V+ D RI++ +
Sbjct: 481 M--------DCHWRRLTSNLFFLAQKPYFPSGNTTLRQQIVYPVKALQVDKDVARITQIL 532
Query: 544 GQANCTKFLANFPDGLQTTVGPRGTQ-LSGGQKQRIALARAFLLDPSILILDEATSALDS 602
+ L GL T V + LS G+ QR++LAR F P I+ LDE+TSA+
Sbjct: 533 EWVKM-EHLVERCGGLDTPVEWDWMKTLSPGELQRLSLARVFYTKPRIVFLDESTSAIGF 591
Query: 603 QSEEVVAQSLQQRSARGKTTISIAHRVSTIQ-HSSRVIVLNRHG 645
+ E + + LQ+ T +SI HR S Q H + V R G
Sbjct: 592 ELEMAIYRKLQEEKI---TFVSIGHRYSLKQFHDMELRVKGRSG 632
>At3g53510 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 739
Score = 68.2 bits (165), Expect = 4e-11
Identities = 60/206 (29%), Positives = 99/206 (47%), Gaps = 22/206 (10%)
Query: 454 RPGEHVCIVGPSGGGKSTVASLLLRYYDIGS--GEIKLGNDNIRDFNLRKYRRLLGVVQQ 511
R GE + ++G SG GKST+ L S G+I L N + + +L K + V Q
Sbjct: 135 REGEMMAVLGASGSGKSTLIDALANRISKESLRGDITL-NGEVLESSLHKV--ISAYVMQ 191
Query: 512 EPMLF-----SGTILDNITYAVPQELVNDE--TRISRAIGQANCTKFLANFPDGLQTTVG 564
+ +LF T++ + + +P L + R+ I Q + +T +G
Sbjct: 192 DDLLFPMLTVEETLMFSAEFRLPSSLSKKKKKARVQALIDQLGLR-------NAAKTVIG 244
Query: 565 PRGTQ-LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTI 623
G + +SGG+++R+++ + DP IL LDE TS LDS S +V + LQ+ + G I
Sbjct: 245 DEGHRGVSGGERRRVSIGTDIIHDPIILFLDEPTSGLDSTSAYMVVKVLQRIAQSGSIVI 304
Query: 624 SIAHRVS--TIQHSSRVIVLNRHGTV 647
H+ S + ++I L+R TV
Sbjct: 305 MSIHQPSYRILGLLDKLIFLSRGNTV 330
>At2g01320 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 725
Score = 68.2 bits (165), Expect = 4e-11
Identities = 57/220 (25%), Positives = 107/220 (47%), Gaps = 16/220 (7%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG-----SGEIKLGNDNIRDFNL 499
+ ++++ +PG + I+GPSG GK+T+ ++L + SG +++ N + +
Sbjct: 90 LLKNVSGEAKPGRLLAIMGPSGSGKTTLLNVLAGQLSLSPRLHLSGLLEV---NGKPSSS 146
Query: 500 RKYRRLLGVVQQEPMLFSG-TILDNITYAVPQEL--VNDETRISRAIGQANCTKFLANFP 556
+ Y+ L V+QE + FS T+ + +++A +L ++ + L +
Sbjct: 147 KAYK--LAFVRQEDLFFSQLTVRETLSFAAELQLPEISSAEERDEYVNNLLLKLGLVSCA 204
Query: 557 DGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRS 616
D RG +SGG+K+R++LA + PS++ DE T+ LD+ E V ++LQ+ +
Sbjct: 205 DSCVGDAKVRG--ISGGEKKRLSLACELIASPSVIFADEPTTGLDAFQAEKVMETLQKLA 262
Query: 617 ARGKTTISIAHRV-STIQHSSRVIVLNRHGTVAETGSFDK 655
G T I H+ ++ IVL GT+ G K
Sbjct: 263 QDGHTVICSIHQPRGSVYAKFDDIVLLTEGTLVYAGPAGK 302
>7290367 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 687
Score = 68.2 bits (165), Expect = 4e-11
Identities = 63/227 (27%), Positives = 109/227 (47%), Gaps = 25/227 (11%)
Query: 441 PQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFN-- 498
P+ H+ +++ PGE + ++G SG GK+T+ + L G I++ +R N
Sbjct: 108 PRKHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQG---IQVSPSGMRLLNGQ 164
Query: 499 ---LRKYRRLLGVVQQEPMLFSG-TILDNITYA----VPQELVNDE--TRISRAIGQANC 548
++ + VQQ+ + T +++ + +P+ L + R+ + I + +
Sbjct: 165 PVDAKEMQARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSL 224
Query: 549 TKFLANFPDGLQTTVGPRGTQ--LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEE 606
+K T +G G LSGG+++R+A A L DP +LI DE TS LDS +
Sbjct: 225 SKCQ-------HTIIGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAH 277
Query: 607 VVAQSLQQRSARGKTTISIAHRVST-IQHSSRVIVLNRHGTVAETGS 652
V Q L++ S +GKT I H+ S+ + I+L G VA G+
Sbjct: 278 SVVQVLKKLSQKGKTVILTIHQPSSELFELFDKILLMAEGRVAFLGT 324
>At3g55090 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 720
Score = 67.8 bits (164), Expect = 6e-11
Identities = 57/215 (26%), Positives = 103/215 (47%), Gaps = 22/215 (10%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGS--GEIKLGNDNIRDFNLRKY 502
+ ++++ R GE + ++G SG GKST+ L GS G + L + ++ R
Sbjct: 91 LLDNISGETRDGEILAVLGASGSGKSTLIDALANRIAKGSLKGTVTLNGEALQS---RML 147
Query: 503 RRLLGVVQQEPMLF-----SGTILDNITYAVPQELVNDET--RISRAIGQANCTKFLANF 555
+ + V Q+ +LF T++ + +P+ L + R+ I Q
Sbjct: 148 KVISAYVMQDDLLFPMLTVEETLMFAAEFRLPRSLPKSKKKLRVQALIDQLGIR------ 201
Query: 556 PDGLQTTVGPRGTQ-LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQ 614
+ +T +G G + +SGG+++R+++ + DP +L LDE TS LDS S +V + L++
Sbjct: 202 -NAAKTIIGDEGHRGISGGERRRVSIGIDIIHDPIVLFLDEPTSGLDSTSAFMVVKVLKR 260
Query: 615 RSARGKTTISIAHRVS--TIQHSSRVIVLNRHGTV 647
+ G I H+ S + R+I L+R TV
Sbjct: 261 IAESGSIIIMSIHQPSHRVLSLLDRLIFLSRGHTV 295
>7293647 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 618
Score = 67.8 bits (164), Expect = 6e-11
Identities = 63/233 (27%), Positives = 103/233 (44%), Gaps = 22/233 (9%)
Query: 418 KDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLL 477
K + E+ I F V P + ++L+F V+ G +V + GP+G GKS++ +L
Sbjct: 389 KGIMCFEDNIIRFEKVPLVTPNGDV--LLQELSFEVKSGTNVLVCGPNGCGKSSLFRILG 446
Query: 478 RYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQE----LV 533
+ G++ + R L V Q P + GT+ D I Y ++ L
Sbjct: 447 ELWPTWGGKVT-----------KPSRGKLFYVPQRPYMTLGTLRDQIIYPHTRDDMRRLG 495
Query: 534 NDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILIL 593
+ + + + T +L +GL + + LSGG+KQRIA+AR F P IL
Sbjct: 496 HSDEDLMHYLDIVQLT-YLEQRENGLDS-IEDWIDVLSGGEKQRIAMARLFYHKPQFAIL 553
Query: 594 DEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGT 646
DE TSA+ S +V + G T +++HR S H + + G+
Sbjct: 554 DECTSAV---SVDVEGKMYSYCREVGITLFTVSHRKSLWAHHDYYLQFDGRGS 603
>YCR011c [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 1049
Score = 67.4 bits (163), Expect = 7e-11
Identities = 59/245 (24%), Positives = 121/245 (49%), Gaps = 24/245 (9%)
Query: 427 SIHFNHVKFSYPT----RPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDI 482
++ F ++ +S P+ + + +++ V+PG+ + I+G SG GK+T+ +L
Sbjct: 383 TLSFENITYSVPSINSDGVEETVLNEISGIVKPGQILAIMGGSGAGKTTLLDILAMKRKT 442
Query: 483 G--SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSG-----TILDNITYAVPQELVND 535
G SG IK+ ++ + + + +++G V Q+ L T+L++ +P+ L +
Sbjct: 443 GHVSGSIKVNGISM---DRKSFSKIIGFVDQDDFLLPTLTVFETVLNSALLRLPKALSFE 499
Query: 536 --ETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILIL 593
+ R+ + + + + + D + RG +SGG+K+R+++A + P +L L
Sbjct: 500 AKKARVYKVLEELR----IIDIKDRIIGNEFDRG--ISGGEKRRVSIACELVTSPLVLFL 553
Query: 594 DEATSALDSQSEEVVAQSLQQRSARGKTT--ISIAHRVSTIQHSSRVIVLNRHGTVAETG 651
DE TS LD+ + V + L + S+ T +SI S I + +VL G + +G
Sbjct: 554 DEPTSGLDASNANNVIECLVRLSSDYNRTLVLSIHQPRSNIFYLFDKLVLLSKGEMVYSG 613
Query: 652 SFDKL 656
+ K+
Sbjct: 614 NAKKV 618
>At1g71960 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 609
Score = 67.4 bits (163), Expect = 7e-11
Identities = 55/194 (28%), Positives = 102/194 (52%), Gaps = 30/194 (15%)
Query: 453 VRPGEHVCIVGPSGGGKSTVASLLL-RYYDIG-SGEIKLGNDNIRDFNLRKYRRLLGVVQ 510
+ PGE + ++GPSG GKST+ + + R + +G+I + + I L++ G V
Sbjct: 38 ISPGEFMAVLGPSGSGKSTLLNAVAGRLHGSNLTGKILINDGKITKQTLKR----TGFVA 93
Query: 511 QEPMLFSG-TILDNITYA----VPQELVND------ETRISRAIGQANCTKFLANFPDGL 559
Q+ +L+ T+ + + + +P+ L D E+ IS +G C
Sbjct: 94 QDDLLYPHLTVRETLVFVALLRLPRSLTRDVKLRAAESVISE-LGLTKCEN--------- 143
Query: 560 QTTVGPRGTQ-LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRS-A 617
T VG + +SGG+++R+++A L++PS+L+LDE TS LD+ + + Q+L +
Sbjct: 144 -TVVGNTFIRGISGGERKRVSIAHELLINPSLLVLDEPTSGLDATAALRLVQTLAGLAHG 202
Query: 618 RGKTTISIAHRVST 631
+GKT ++ H+ S+
Sbjct: 203 KGKTVVTSIHQPSS 216
>Hs10947131 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 592
Score = 67.0 bits (162), Expect = 9e-11
Identities = 60/204 (29%), Positives = 96/204 (46%), Gaps = 21/204 (10%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+ +DL+ + G+ + I G +G GK+++ +L + G +++ + DF
Sbjct: 403 LIKDLSLKISEGQSLLITGNTGTGKTSLLRVLGGLWTSTRGSVQM----LTDFGPHGVLF 458
Query: 505 LLGVVQQEPMLFSGTILDNITYAV----PQELVNDETRISRAIGQANCTKFLANFPDGLQ 560
L Q+P GT+ + + Y + P D+ RI R + A + +A +GL
Sbjct: 459 L----PQKPFFTDGTLREQVIYPLKEVYPDSGSADDERILRFLELAGLSNLVAR-TEGLD 513
Query: 561 TTVGPRGTQ-LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARG 619
V LS G+ QR++ AR F L P +LDEATSAL +EEV ++ + G
Sbjct: 514 QQVDWNWYDVLSPGEMQRLSFARLFYLQPKYAVLDEATSAL---TEEVESELYRIGQQLG 570
Query: 620 KTTISIAHRVSTIQHSSRVIVLNR 643
T IS+ HR Q +V VL R
Sbjct: 571 MTFISVGHR----QSLEKVPVLTR 590
>At5g13580 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 727
Score = 66.6 bits (161), Expect = 1e-10
Identities = 63/232 (27%), Positives = 108/232 (46%), Gaps = 30/232 (12%)
Query: 436 SYPTRPQHHIFEDLNFTV--------RPGEHVCIVGPSGGGKSTVASLLLRYYDIGS--G 485
S P P IF T+ R GE + ++G SG GKST+ L GS G
Sbjct: 91 SDPGAPSEGIFSSKTKTLLNGITGEARDGEILAVLGASGSGKSTLIDALANRIAKGSLKG 150
Query: 486 EIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSG-TILDNITYAVPQELVNDETRISRAIG 544
+ L + + N + + + V Q+ +LF T+ + + +A E R+ R++
Sbjct: 151 NVTLNGEVL---NSKMQKAISAYVMQDDLLFPMLTVEETLMFAA-------EFRLPRSLS 200
Query: 545 QANCTKFLANFPDGL------QTTVGPRGTQ-LSGGQKQRIALARAFLLDPSILILDEAT 597
++ + + D L T +G G + +SGG+++R+++ + DP +L LDE T
Sbjct: 201 KSKKSLRVQALIDQLGLRNAANTVIGDEGHRGISGGERRRVSIGIDIIHDPILLFLDEPT 260
Query: 598 SALDSQSEEVVAQSLQQRSARGKTTISIAHRVS--TIQHSSRVIVLNRHGTV 647
S LDS S V + L++ + G I H+ S ++ R++ L+R TV
Sbjct: 261 SGLDSTSALSVIKVLKRIAQSGSMVIMTLHQPSYRLLRLLDRLLFLSRGQTV 312
>At5g64840 [R] KOG0927 Predicted transporter (ABC superfamily)
Length = 692
Score = 66.2 bits (160), Expect = 2e-10
Identities = 51/183 (27%), Positives = 91/183 (48%), Gaps = 23/183 (12%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+F+ N ++ GE + I+GP+G GKST+ L++ GE+ LG N+ L Y
Sbjct: 439 LFKKANLSIERGEKIAILGPNGCGKSTLLKLIMGLEKPVKGEVILGEHNV----LPNY-- 492
Query: 505 LLGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVG 564
Q E + T+L+ + A +D I +G+ N F A+ D
Sbjct: 493 -FEQNQAEVLDLDKTVLETVCEAAEDWRSDD---IKGLLGRCN---FKADMLD------- 538
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
+ + LSGG+K R+A + + ++L+LDE T+ LD S+E++ +++ + T I+
Sbjct: 539 RKVSLLSGGEKARLAFCKFMVTPSTLLVLDEPTNHLDIPSKEMLEEAINEYQG---TVIA 595
Query: 625 IAH 627
++H
Sbjct: 596 VSH 598
>At2g37360 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 755
Score = 65.5 bits (158), Expect = 3e-10
Identities = 54/187 (28%), Positives = 90/187 (47%), Gaps = 20/187 (10%)
Query: 454 RPGEHVCIVGPSGGGKSTVASLLLRYY--DIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQ 511
R GE + ++G SG GKST+ L D G I L N + + +++K + V Q
Sbjct: 142 REGEMMAVLGASGSGKSTLIDALANRIAKDSLRGSITL-NGEVLESSMQKV--ISAYVMQ 198
Query: 512 EPMLF-----SGTILDNITYAVPQELVNDE--TRISRAIGQANCTKFLANFPDGLQTTVG 564
+ +LF T++ + + +P+ L + R+ I Q +T +G
Sbjct: 199 DDLLFPMLTVEETLMFSAEFRLPRSLSKKKKKARVQALIDQLGLRS-------AAKTVIG 251
Query: 565 PRGTQ-LSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTI 623
G + +SGG+++R+++ + DP IL LDE TS LDS S +V + LQ+ + G I
Sbjct: 252 DEGHRGVSGGERRRVSIGNDIIHDPIILFLDEPTSGLDSTSAYMVIKVLQRIAQSGSIVI 311
Query: 624 SIAHRVS 630
H+ S
Sbjct: 312 MSIHQPS 318
>CE09356 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 1447
Score = 65.1 bits (157), Expect = 4e-10
Identities = 55/197 (27%), Positives = 95/197 (47%), Gaps = 12/197 (6%)
Query: 449 LNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGV 508
LN + G+ ++G +G GK+T S+L Y SG K+ +IR +LR+ R +LG+
Sbjct: 349 LNLRLYEGQITGLLGHNGAGKTTTMSILCGLYAPSSGTAKIYQRDIRT-DLRRVRDVLGI 407
Query: 509 VQQEPMLFSG-TILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRG 567
Q +LFS T+ + + + V D S+ + LA+ L
Sbjct: 408 CPQHNVLFSHLTVSEQLRLFAALKGVPDSELTSQV------DEILASV--SLTEKANKLA 459
Query: 568 TQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAH 627
+ LSGG K+R+ + AF+ +ILDE T+ +D + + + L QR+ G+T + H
Sbjct: 460 STLSGGMKRRLCIGIAFIGGSRFVILDEPTAGVDVTARKDI-WKLLQRNKEGRTILLSTH 518
Query: 628 RVSTIQ-HSSRVIVLNR 643
+ S R+ +L++
Sbjct: 519 HMDEADVLSDRIAILSQ 535
Score = 58.2 bits (139), Expect = 4e-08
Identities = 46/208 (22%), Positives = 104/208 (49%), Gaps = 14/208 (6%)
Query: 441 PQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRD---F 497
P+ + ++F V PGE ++G +G GK+T ++L G G I++ N I
Sbjct: 1171 PELLAVKGISFAVEPGECFGLLGLNGAGKTTTFAMLTAKIRPGHGSIEMQNTRINTGSFS 1230
Query: 498 NLRKYRRLLGVVQQEPMLFSGTILDNIT-YAVPQELVNDETRISRAIGQANCTKFLANFP 556
++R +++L Q + + + +N+ YA + +V T+I I + L +
Sbjct: 1231 DVRNFQQLGYCPQFDALNMKLSTRENLKFYARIRGIV--PTQIDSIIDRLLIALHLRPYA 1288
Query: 557 DGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRS 616
+ + + LSGG ++++++A A + PS++ LDE ++ +D S++ + + +++
Sbjct: 1289 N-------TQTSSLSGGNRRKLSVAVALVSQPSLIFLDEPSAGMDPGSQQFLWKVIERLC 1341
Query: 617 ARGKTTISIAHRVSTIQH-SSRVIVLNR 643
GK + +H + + +R+ +++R
Sbjct: 1342 KSGKAVVLTSHSMEECEALCTRIAIMDR 1369
>CE05663 [J] KOG0066 eIF2-interacting protein ABC50 (ABC superfamily)
Length = 622
Score = 63.9 bits (154), Expect = 8e-10
Identities = 56/180 (31%), Positives = 81/180 (44%), Gaps = 44/180 (24%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRR 504
+F+ LNF V + IVGP+G GKST+ LL+ D GE LRK+R
Sbjct: 419 LFKKLNFGVDMDSRIAIVGPNGVGKSTLLKLLIGKIDPNDGE------------LRKHRT 466
Query: 505 L-LGVVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTV 563
L +G Q E +N E + CTKF ++ + + +
Sbjct: 467 LRIGWFDQHA----------------NEALNGEQTPVEFL----CTKFNIDYQEA-RKQL 505
Query: 564 GPRGT----------QLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQ 613
G G LSGGQK R+AL L P I+ILDE T+ LD +S + +A++++
Sbjct: 506 GTTGLAAHAHTVKIKDLSGGQKSRVALCNLALGGPDIIILDEPTNNLDIESIDALAEAIR 565
Score = 55.1 bits (131), Expect = 4e-07
Identities = 48/167 (28%), Positives = 80/167 (47%), Gaps = 11/167 (6%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL-LRYYDIGSG--------EIKLGNDNIR 495
+F+ + T+ G +VGP+G GK+T+ + R I S EI++ + +
Sbjct: 94 LFDKASLTIVYGRRYGLVGPNGMGKTTLLKHIGARKLAIPSHIDLLYCEQEIQVDSTSAI 153
Query: 496 DFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETR-ISRAIGQANCTKFLAN 554
D ++ ++ L ++++E L S A + V DE R I + + LA
Sbjct: 154 DTVVKSDKKRLALLEEEAKLMSEIEEGKTEAAERMKEVADELRDIGADSAEPRARRILAG 213
Query: 555 FPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALD 601
+ P T SGG + RI+LARA L+P++L+LDE T+ LD
Sbjct: 214 LGFSKEMQEKPC-TDFSGGWRMRISLARALFLEPTLLMLDEPTNHLD 259
>CE02546 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 665
Score = 63.9 bits (154), Expect = 8e-10
Identities = 58/235 (24%), Positives = 104/235 (43%), Gaps = 24/235 (10%)
Query: 417 GKDPVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLL 476
G + ++ I F+ V P + E L+F V G +V + GP+G GKS++ L
Sbjct: 435 GSGKLLAQDNMIKFDEVPLVTPNGDI--LIESLSFEVPSGRNVLVCGPNGCGKSSLFRTL 492
Query: 477 LRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYA-----VPQE 531
+ + G + + + L V Q P + GT+ D + Y + +
Sbjct: 493 GELWPVMGGTLT-----------KPAKGKLFYVPQRPYMTLGTLRDQVIYPDTSFDMKMK 541
Query: 532 LVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSIL 591
++D+ + + + T L +G + V LSGG+KQRIA+AR F P
Sbjct: 542 GMSDKD-LEQMLENVQLTNILER--EGGWSAVQDWMDVLSGGEKQRIAMARLFYHKPQFA 598
Query: 592 ILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGT 646
ILDE TSA+ E + + ++ + T +++HR S ++ + ++ G+
Sbjct: 599 ILDECTSAVSVDVEGAMYRLCREMNI---TLFTVSHRKSLWKYHEYSLYMDGRGS 650
>At1g71330 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 324
Score = 63.9 bits (154), Expect = 8e-10
Identities = 36/123 (29%), Positives = 64/123 (51%), Gaps = 1/123 (0%)
Query: 535 DETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILD 594
D R + I + +K L G QT +G RG LSGGQKQRI +ARA D I + D
Sbjct: 2 DRERYDKVIEACSLSKDLEILSFGDQTVIGERGINLSGGQKQRIHIARALYQDADIYLFD 61
Query: 595 EATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAETGSFD 654
+ SA+D+ + + + + K+ I + H+V + + +V+ + G +++ G ++
Sbjct: 62 DPFSAVDAHTGSHLFKEALRGLLCSKSVIYVTHQVEFLPSADLTLVM-KDGRISQAGKYN 120
Query: 655 KLI 657
++
Sbjct: 121 DIL 123
>7296258 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 643
Score = 63.9 bits (154), Expect = 8e-10
Identities = 55/188 (29%), Positives = 93/188 (49%), Gaps = 10/188 (5%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDI-GSGEIKLGNDNIRDFNLRKYR 503
I +N E I+GPSG GK+T+ +LL + + SGEI L N++ RD +R +R
Sbjct: 75 ILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLAGFGAVCESGEI-LVNNSPRD--MRVFR 131
Query: 504 RLLGVVQQEPMLFSG-TILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTT 562
++ + Q +L S T+L+ + A +L E + + + + + D L T
Sbjct: 132 KMSRYIMQTDVLDSQFTVLEMMILAANLKL-GKELNLKQKLEVIDEILGMLRLKDTLNTM 190
Query: 563 VGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTT 622
+LSGG+++R+ +A + +P ++ LDE T+ LD S L+ +A G+T
Sbjct: 191 A----QKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTV 246
Query: 623 ISIAHRVS 630
I H S
Sbjct: 247 ICSIHTPS 254
>Hs9945308 [I] KOG0064 Peroxisomal long-chain acyl-CoA transporter ABC
superfamily
Length = 740
Score = 62.8 bits (151), Expect = 2e-09
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 16/199 (8%)
Query: 449 LNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGV 508
LNF V G H+ I GP+G GKS++ +L + + G + + + +
Sbjct: 497 LNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVL-----------YKPPPQHMFY 545
Query: 509 VQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFP--DGLQTTVGPR 566
+ Q P + G++ D + Y + ++D+ + + + L + +G V
Sbjct: 546 IPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWDAVMDW 605
Query: 567 GTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIA 626
LSGG+KQR+ +AR F P +LDE TSA+ S +V + Q G + +SI
Sbjct: 606 KDVLSGGEKQRMGMARMFYHKPKYALLDECTSAV---SIDVEGKIFQAAKGAGISLLSIT 662
Query: 627 HRVSTIQHSSRVIVLNRHG 645
HR S ++ + ++ + G
Sbjct: 663 HRPSLWKYHTHLLQFDGEG 681
>CE20234 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 1802
Score = 62.8 bits (151), Expect = 2e-09
Identities = 56/206 (27%), Positives = 95/206 (45%), Gaps = 13/206 (6%)
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLG 507
+LN + PG+ ++G +G GKST S+L SG + + +IR +L K RR +G
Sbjct: 617 NLNLKMYPGQCTVLLGHNGAGKSTTFSMLTGVASPSSGSAYVNDFDIRT-SLPKIRREMG 675
Query: 508 VVQQEPMLFSG-TILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPR 566
+ Q LF T+++++ + + + +R I F A+F G
Sbjct: 676 LCPQYNTLFGFMTVMEHLEFFAKLKERTWDPEEAREILARLRIDFKADFMAGA------- 728
Query: 567 GTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIA 626
LSGGQK++++LA A + +++LDE TS +D + +L QR +T +
Sbjct: 729 ---LSGGQKRKLSLAIALIGGSEVVMLDEPTSGMDPGARH-ETWTLIQREKERRTILLTT 784
Query: 627 HRVSTIQHSSRVIVLNRHGTVAETGS 652
H + I + HG + GS
Sbjct: 785 HFMEEADLLGDRIAIMAHGQLECCGS 810
>At3g53480 [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-15) ABC
superfamily
Length = 1450
Score = 62.4 bits (150), Expect = 2e-09
Identities = 52/215 (24%), Positives = 104/215 (48%), Gaps = 14/215 (6%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG--SGEIKL-GNDNIRDFNLRK 501
+ D+ RPG ++G SG GK+T+ +L G G+I++ G +++
Sbjct: 877 LLSDITGAFRPGILTALMGVSGAGKTTLLDVLAGRKTSGYIEGDIRISGFPKVQE----T 932
Query: 502 YRRLLGVVQQEPMLFSG-TILDNITYAVPQELVN--DETRISRAIGQANCTKFLANFPDG 558
+ R+ G +Q + T+ +++ Y+ L D T ++ + Q T L D
Sbjct: 933 FARVSGYCEQTDIHSPNITVEESVIYSAWLRLAPEIDATTKTKFVKQVLETIELDEIKDS 992
Query: 559 LQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSAR 618
L G G LS Q++R+ +A + +PSI+ +DE T+ LD+++ +V ++++ +
Sbjct: 993 LVGVTGVSG--LSTEQRKRLTIAVELVANPSIIFMDEPTTGLDARAAAIVMRAVKNVADT 1050
Query: 619 GKTTISIAHR--VSTIQHSSRVIVLNRHGTVAETG 651
G+T + H+ + + +++L R G + TG
Sbjct: 1051 GRTIVCTIHQPSIDIFEAFDELVLLKRGGRMIYTG 1085
>At4g33460 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 270
Score = 62.0 bits (149), Expect = 3e-09
Identities = 65/274 (23%), Positives = 112/274 (40%), Gaps = 37/274 (13%)
Query: 396 AGAAARVFELNDRKPLIHPTIGKDPVTLENKSIHFNHVKFSYPTRP--QHHIFEDLNFTV 453
A + R+F L + P+ +N ++ ++ FS TR I D +F +
Sbjct: 8 AASPPRLFPLRSISSSVSPSGSYRIKFSDNVAVECRNLCFSVSTRQGISVPILRDCSFRI 67
Query: 454 RPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEP 513
G+ I+GP+G GKST+ +L + SG + + F ++ ++ V+ +
Sbjct: 68 PSGQLWMILGPNGCGKSTLLKILAGVVNPSSGTVFVEKPKNFVFQNPDHQVVMPTVEADV 127
Query: 514 MLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFL-------ANFPDGLQTTVGPR 566
G D V ++ + A+G + +FL F +QT
Sbjct: 128 AFGLGKYHDMNQEEVKSRVI----KALEAVGMRDYMQFLLLKYRFWCCFQRPIQT----- 178
Query: 567 GTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIA 626
LSGGQKQRIA+A A +L+LDE T+ LD ++ T + +
Sbjct: 179 ---LSGGQKQRIAIAGALAEACKVLLLDELTTFLDESDQK-----------GDVTALWVT 224
Query: 627 HRVSTIQHSSRVIVLN-----RHGTVAETGSFDK 655
HR+ ++++ + + RHG A F K
Sbjct: 225 HRLEELKYADGAVYMENGRVVRHGDAATISDFIK 258
>At2g37280 [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-15) ABC
superfamily
Length = 1413
Score = 62.0 bits (149), Expect = 3e-09
Identities = 55/216 (25%), Positives = 108/216 (49%), Gaps = 16/216 (7%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG--SGEIKL-GNDNIRDFNLRK 501
+ ++ RPG ++G SG GK+T+ +L G GEI++ G +++
Sbjct: 840 LLSEITGAFRPGVLTALMGISGAGKTTLLDVLAGRKTSGYIEGEIRISGFLKVQE----T 895
Query: 502 YRRLLGVVQQEPMLF-SGTILDNITYAVPQELV---NDETRISRAIGQANCTKFLANFPD 557
+ R+ G +Q + S T+ +++ Y+ LV N +T+I R + Q T L D
Sbjct: 896 FARVSGYCEQTDIHSPSITVEESLIYSAWLRLVPEINPQTKI-RFVKQVLETIELEEIKD 954
Query: 558 GLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSA 617
L G G LS Q++R+ +A + +PSI+ +DE T+ LD+++ +V ++++ +
Sbjct: 955 ALVGVAGVSG--LSTEQRKRLTVAVELVANPSIIFMDEPTTGLDARAAAIVMRAVKNVAE 1012
Query: 618 RGKTTISIAHR--VSTIQHSSRVIVLNRHGTVAETG 651
G+T + H+ + + +++L R G + +G
Sbjct: 1013 TGRTIVCTIHQPSIHIFEAFDELVLLKRGGRMIYSG 1048
>Hs17865630 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 1642
Score = 61.2 bits (147), Expect = 5e-09
Identities = 52/212 (24%), Positives = 103/212 (48%), Gaps = 14/212 (6%)
Query: 419 DPVTLE---NKSIHFNHVKFSYPTRPQH-HIFEDLNFTVRPGEHVCIVGPSGGGKSTVAS 474
+PV+ E ++I + ++ +Y + ++ +L+F + G+ ++G SG GKST+ +
Sbjct: 466 EPVSSEFVGKEAIRISGIQKTYRKKGENVEALRNLSFDIYEGQITALLGHSGTGKSTLMN 525
Query: 475 LLLRYYDIGSGEIKLGNDNIRDFN-LRKYRRLLGVVQQEPMLFSG-TILDNITYAVPQEL 532
+L G + + + + + + R+++G+ Q + F T+ +N++ +
Sbjct: 526 ILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVLTVEENLSILASIKG 585
Query: 533 VNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILI 592
+ I K L + +QT + +LSGGQK++++L A L +P IL+
Sbjct: 586 IPANNIIQEV------QKVLLDLD--MQTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILL 637
Query: 593 LDEATSALDSQSEEVVAQSLQQRSARGKTTIS 624
LDE T+ +D S +V L+ R A T S
Sbjct: 638 LDEPTAGMDPCSRHIVWNLLKYRKANRVTVFS 669
Score = 51.6 bits (122), Expect = 4e-06
Identities = 42/161 (26%), Positives = 79/161 (48%), Gaps = 13/161 (8%)
Query: 449 LNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGV 508
++F V+ GE + ++GP+G GKST+ ++L+ + SG++ LG+ + + +G
Sbjct: 1319 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGY 1378
Query: 509 VQQEPMLFSGTILD---NITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGP 565
Q L+ T L I AV +D + I A + + LQ TV
Sbjct: 1379 CPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHA------LDLKEHLQKTV-- 1430
Query: 566 RGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEE 606
+L G K+++ A + L +P I +LDE ++ +D ++++
Sbjct: 1431 --KKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQ 1469
>YOR153w [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-15) ABC
superfamily
Length = 1511
Score = 60.8 bits (146), Expect = 7e-09
Identities = 59/248 (23%), Positives = 118/248 (46%), Gaps = 20/248 (8%)
Query: 415 TIGKDPVTLENKSIHFNHVKFSYPTRPQ-HHIFEDLNFTVRPGEHVCIVGPSGGGKSTVA 473
T G+ ++ H+ ++ + + + I +++ V+PG ++G SG GK+T+
Sbjct: 856 TYGEIGLSKSEAIFHWRNLCYEVQIKAETRRILNNVDGWVKPGTLTALMGASGAGKTTLL 915
Query: 474 SLLLRYYDIG--SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPM-LFSGTILDNITYAV-- 528
L +G +G+I L N RD + + R +G QQ+ + L + T+ +++ ++
Sbjct: 916 DCLAERVTMGVITGDI-LVNGIPRD---KSFPRSIGYCQQQDLHLKTATVRESLRFSAYL 971
Query: 529 --PQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLL 586
P E+ +E +R + + + + D + VG G L+ Q++R+ +
Sbjct: 972 RQPAEVSIEEK--NRYVEEVIKILEMEKYADAV---VGVAGEGLNVEQRKRLTIGVELTA 1026
Query: 587 DPSILI-LDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVSTI--QHSSRVIVLNR 643
P +L+ LDE TS LDSQ+ + Q +++ + G+ + H+ S I Q R++ + R
Sbjct: 1027 KPKLLVFLDEPTSGLDSQTAWSICQLMKKLANHGQAILCTIHQPSAILMQEFDRLLFMQR 1086
Query: 644 HGTVAETG 651
G G
Sbjct: 1087 GGKTVYFG 1094
>Hs4501849 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 1704
Score = 60.8 bits (146), Expect = 7e-09
Identities = 49/180 (27%), Positives = 81/180 (44%), Gaps = 9/180 (5%)
Query: 448 DLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLG 507
DLN + G+ ++G +G GK+T S+L + SG + I ++ + R+ LG
Sbjct: 551 DLNLNLYEGQITVLLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQ-DMVQIRKSLG 609
Query: 508 VVQQEPMLFSGTILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRG 567
+ Q +LF DN+T A +SR + L GL+ R
Sbjct: 610 LCPQHDILF-----DNLTVAEHLYFYAQLKGLSRQKCPEEVKQMLHII--GLEDKWNSRS 662
Query: 568 TQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAH 627
LSGG ++++++ A + +LILDE TS +D+ S + L QR +T + H
Sbjct: 663 RFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDAISRRAI-WDLLQRQKSDRTIVLTTH 721
>YPL058c [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-15) ABC
superfamily
Length = 1511
Score = 59.3 bits (142), Expect = 2e-08
Identities = 57/253 (22%), Positives = 117/253 (45%), Gaps = 28/253 (11%)
Query: 414 PTIGKDPVTLENKSIHFNHVKFSYP-TRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTV 472
P + + V E +NH+ ++ P + D+ V+PG+ ++G SG GK+T+
Sbjct: 828 PNVDLEKVIAEKDVFTWNHLDYTIPYDGATRKLLSDVFGYVKPGKMTALMGESGAGKTTL 887
Query: 473 ASLLLRYYDIG--SGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYA--- 527
++L + ++G +G++ + N + R V Q + + ++ +++ +A
Sbjct: 888 LNVLAQRINMGVITGDMLV---NAKPLPASFNRSCGYVAQADNHMAELSVRESLRFAAEL 944
Query: 528 -----VP-QELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALA 581
VP +E +I +G N + L VG G L+ Q++++++
Sbjct: 945 RQQSSVPLEEKYEYVEKIITLLGMQNYAEAL----------VGKTGRGLNVEQRKKLSIG 994
Query: 582 RAFLLDPSILI-LDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHRVST--IQHSSRV 638
+ PS+L+ LDE TS LDSQS + Q ++ + G++ + H+ S + R+
Sbjct: 995 VELVAKPSLLLFLDEPTSGLDSQSAWSIVQFMRALADSGQSILCTIHQPSATLFEQFDRL 1054
Query: 639 IVLNRHGTVAETG 651
++L + G + G
Sbjct: 1055 LLLKKGGKMVYFG 1067
>YDR011w [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-15) ABC
superfamily
Length = 1501
Score = 58.9 bits (141), Expect = 3e-08
Identities = 56/214 (26%), Positives = 100/214 (46%), Gaps = 26/214 (12%)
Query: 455 PGEHVCIVGPSGGGKSTVASLLL-RYYDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEP 513
PG ++G SG GK+T+ + L R I +G++ + N R + RR V QQ+
Sbjct: 881 PGTMTALMGESGAGKTTLLNTLAQRNVGIITGDMLV---NGRPIDASFERRTGYVQQQDI 937
Query: 514 MLFSGTILDNITYAV----PQELVNDET-----RISRAIGQANCTKFLANFPDGLQTTVG 564
+ T+ +++ ++ PQ L + E +I R +G + L VG
Sbjct: 938 HIAELTVRESLQFSARMRRPQHLPDSEKMDYVEKIIRVLGMEEYAEAL----------VG 987
Query: 565 PRGTQLSGGQKQRIALARAFLLDPSILI-LDEATSALDSQSEEVVAQSLQQRSARGKTTI 623
G L+ Q++++++ + P +L+ LDE TS LDSQS + Q L++ S G++ +
Sbjct: 988 EVGCGLNVEQRKKLSIGVELVAKPDLLLFLDEPTSGLDSQSSWAIIQLLRKLSKAGQSIL 1047
Query: 624 SIAHRVST--IQHSSRVIVLNRHGTVAETGSFDK 655
H+ S + R+++L + G G K
Sbjct: 1048 CTIHQPSATLFEEFDRLLLLRKGGQTVYFGDIGK 1081
>SPBC29A3.09c [EJ] KOG0062 ATPase component of ABC transporters with duplicated
ATPase domains/Translation elongation factor EF-3b
Length = 736
Score = 58.9 bits (141), Expect = 3e-08
Identities = 58/230 (25%), Positives = 98/230 (42%), Gaps = 31/230 (13%)
Query: 420 PVTLENKSIHFNHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRY 479
P L+ ++F +V P H I + ++ V+ + +VGP+G GKST+ LL+
Sbjct: 515 PPILQMSDVNFEYV-------PGHPILKHVDIDVQMDSRIGVVGPNGAGKSTMLKLLIEQ 567
Query: 480 YDIGSGEIKLGNDNIRDFNLRKYRRLLGVVQQEPMLFSGTILDNITYAVPQELVNDETRI 539
SG + R R + Q + L+ +++ E
Sbjct: 568 LHPTSGIVS-----------RHPRLRIAYFAQHHVDTLDLNLNALSFLAKTFPGKGEEEY 616
Query: 540 SRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSA 599
R +G F + P LQ + LSGGQK R+A A L +P ILILDE T+
Sbjct: 617 RRHLG-----AFGVSGPLALQKMI-----TLSGGQKSRVAFACLGLQNPHILILDEPTNH 666
Query: 600 LDSQSEEVVAQSLQQRSARGKTTISIAHRVSTIQHSSRVIVLNRHGTVAE 649
LD +S + + +++++ I ++H V + + I H V++
Sbjct: 667 LDMESMDALTRAVKRFQG---GVILVSHDVDFLDKTCTSIWQCDHNVVSK 713
>At2g36380 [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-15) ABC
superfamily
Length = 1450
Score = 58.9 bits (141), Expect = 3e-08
Identities = 50/213 (23%), Positives = 97/213 (45%), Gaps = 8/213 (3%)
Query: 445 IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDF--NLRKY 502
+ D+ RPG +VG SG GK+T+ +L G E G+ NI + N +
Sbjct: 876 LLRDVGGAFRPGVLTALVGVSGAGKTTLMDVLAGRKTGGYVE---GSINISGYPKNQATF 932
Query: 503 RRLLGVVQQEPMLFSG-TILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQT 561
R+ G +Q + T+ +++ Y+ L D +R + + + P
Sbjct: 933 ARVSGYCEQNDIHSPHVTVYESLIYSAWLRLSADIDTKTREMFVEEVMELVELKPLRNSI 992
Query: 562 TVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKT 621
P LS Q++R+ +A + +PSI+ +DE TS LD+++ +V ++++ G+T
Sbjct: 993 VGLPGVDGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRT 1052
Query: 622 TISIAHR--VSTIQHSSRVIVLNRHGTVAETGS 652
+ H+ + + ++++ R G V G+
Sbjct: 1053 VVCTIHQPSIDIFESFDELLLMKRGGQVIYAGT 1085
>YOR328w [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-15) ABC
superfamily
Length = 1564
Score = 58.5 bits (140), Expect = 3e-08
Identities = 53/236 (22%), Positives = 113/236 (47%), Gaps = 16/236 (6%)
Query: 429 HFNHVKFSYPTRP-QHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG--SG 485
H+ ++ + P + + I ++++ V+PG ++G SG GK+T+ L +G +G
Sbjct: 924 HWKNLCYDIPIKNGKRRILDNVDGWVKPGTLTALIGASGAGKTTLLDCLAERTTMGLITG 983
Query: 486 EIKLGNDNIRDFNLRKYRRLLGVVQQEPM-LFSGTILDNITYAVPQELVNDET--RISRA 542
++ + + RD + + R +G QQ+ + L + T+ +++ ++ +D + +
Sbjct: 984 DVFV-DGRPRD---QSFPRSIGYCQQQDLHLKTATVRESLRFSAYLRQADDVSIEEKDKY 1039
Query: 543 IGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILI-LDEATSALD 601
+ + + + D + VG G L+ Q++R+ + P +L+ LDE TS LD
Sbjct: 1040 VEEVIEVLEMKLYADAI---VGVPGEGLNVEQRKRLTIGVELAAKPKLLVFLDEPTSGLD 1096
Query: 602 SQSEEVVAQSLQQRSARGKTTISIAHRVSTI--QHSSRVIVLNRHGTVAETGSFDK 655
SQ+ Q +++ ++RG+ + H+ S + Q R++ L G G K
Sbjct: 1097 SQTAWSTCQLMKKLASRGQAILCTIHQPSALLMQEFDRLLFLQEGGQTVYFGELGK 1152
>Hs4557876 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 2273
Score = 58.5 bits (140), Expect = 3e-08
Identities = 52/205 (25%), Positives = 91/205 (44%), Gaps = 11/205 (5%)
Query: 449 LNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGEIKLGNDNIRDFNLRKYRRLLGV 508
LN T + +G +G GK+T S+L SG + +G +I + +L R+ LG+
Sbjct: 949 LNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDI-ETSLDAVRQSLGM 1007
Query: 509 VQQEPMLFSG-TILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRG 567
Q +LF T+ +++ + + + E Q L + GL
Sbjct: 1008 CPQHNILFHHLTVAEHMLFYAQLKGKSQEE------AQLEMEAMLED--TGLHHKRNEEA 1059
Query: 568 TQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAH 627
LSGG ++++++A AF+ D ++ILDE TS +D S + L + G+T I H
Sbjct: 1060 QDLSGGMQRKLSVAIAFVGDAKVVILDEPTSGVDPYSRRSI-WDLLLKYRSGRTIIMPTH 1118
Query: 628 RVSTIQHSSRVIVLNRHGTVAETGS 652
+ H I + G + +G+
Sbjct: 1119 HMDEADHQGDRIAIIAQGRLYCSGT 1143
>Hs17933764 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 1617
Score = 58.5 bits (140), Expect = 3e-08
Identities = 56/208 (26%), Positives = 97/208 (45%), Gaps = 20/208 (9%)
Query: 419 DPVTLE---NKSIHFNHVKFSYPTRP-QHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVAS 474
+PV E ++I +VK Y + + + L F + G+ I+G SG GKS++ +
Sbjct: 466 EPVAPEFQGKEAIRIRNVKKEYKGKSGKVEALKGLLFDIYEGQITAILGHSGAGKSSLLN 525
Query: 475 LLLRYYDIGSGEIKLGNDNIRDF-NLRKYRRLLGVVQQEPMLFSG-TILDNITYAVPQE- 531
+L G + + N N+ + +L + R++ GV Q + F T+ +N++ +
Sbjct: 526 ILNGLSVPTEGSVTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDILTVKENLSLFAKIKG 585
Query: 532 --LVNDETRISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPS 589
L E + R + + + + N D L LS GQK+++ L DP
Sbjct: 586 IHLKEVEQEVQRILLELD----MQNIQDNL-------AKHLSEGQKRKLTFGITILGDPQ 634
Query: 590 ILILDEATSALDSQSEEVVAQSLQQRSA 617
IL+LDE T+ LD S + V L++R A
Sbjct: 635 ILLLDEPTTGLDPFSRDQVWSLLRERRA 662
>At3g16340 [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-15) ABC
superfamily
Length = 1416
Score = 58.5 bits (140), Expect = 3e-08
Identities = 54/244 (22%), Positives = 114/244 (46%), Gaps = 17/244 (6%)
Query: 420 PVTLENKSIHF-----NHVKFSYPTRPQHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVAS 474
P+T+ ++++ +K ++ + + +++ RPG ++G SG GK+T+
Sbjct: 811 PLTMSFDNVNYYVDMPKEMKEQGVSKDKLQLLKEVTGVFRPGVLTALMGVSGAGKTTLMD 870
Query: 475 LLLRYYDIGSGEIKLGNDNIRDFNLRK--YRRLLGVVQQEPMLFSG-TILDNITYAVPQE 531
+L G E G+ I F R+ + R+ G +Q + T+ +++ Y+
Sbjct: 871 VLAGRKTGGYIE---GDIRISGFPKRQETFARISGYCEQNDIHSPQVTVKESLIYSAFLR 927
Query: 532 LVNDETRIS--RAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPS 589
L + T+ R + + L + D + G G LS Q++R+ +A + +PS
Sbjct: 928 LPKEVTKYEKMRFVDEVMELVELESLKDAVVGLPGITG--LSTEQRKRLTIAVELVANPS 985
Query: 590 ILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIAHR--VSTIQHSSRVIVLNRHGTV 647
I+ +DE TS LD+++ +V ++++ G+T + H+ + + +++L R G V
Sbjct: 986 IIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFEAFDELLLLKRGGQV 1045
Query: 648 AETG 651
G
Sbjct: 1046 IYAG 1049
>At2g41700 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 1850
Score = 58.5 bits (140), Expect = 3e-08
Identities = 53/206 (25%), Positives = 97/206 (46%), Gaps = 13/206 (6%)
Query: 449 LNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIGSGE-IKLGNDNIRDFNLRKYRRLLG 507
L T+ + + ++G +G GKST S+L+ SG+ + LGN I N+ + R+ LG
Sbjct: 505 LQLTLYENQILSLLGHNGAGKSTTISMLVGLLPPTSGDALILGNSIIT--NMDEIRKELG 562
Query: 508 VVQQEPMLFSG-TILDNITYAVPQELVNDETRISRAIGQANCTKFLANFPDGLQTTVGPR 566
V Q +LF T+ +++ + V + + S + A GL +
Sbjct: 563 VCPQHDILFPELTVREHLEMFAVLKGVEEGSLKSTVVDMAEEV--------GLSDKINTL 614
Query: 567 GTQLSGGQKQRIALARAFLLDPSILILDEATSALDSQSEEVVAQSLQQRSARGKTTISIA 626
LSGG K++++L A + + ++ILDE TS +D S + Q L ++ +G+ +
Sbjct: 615 VRALSGGMKRKLSLGIALIGNSKVIILDEPTSGMDPYSMRLTWQ-LIKKIKKGRIILLTT 673
Query: 627 HRVSTIQHSSRVIVLNRHGTVAETGS 652
H + + I + +G++ GS
Sbjct: 674 HSMDEAEELGDRIGIMANGSLKCCGS 699
Score = 53.5 bits (127), Expect = 1e-06
Identities = 57/206 (27%), Positives = 101/206 (48%), Gaps = 16/206 (7%)
Query: 424 ENKSIHFNHVKFSYPTRPQHH---IFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYY 480
+N ++ +++ YP H + L F+V+ GE +G +G GK+T S+L
Sbjct: 1411 DNTMLYLQNLRKVYPGDKHHGPKVAVQSLTFSVQAGECFGFLGTNGAGKTTTLSMLSGEE 1470
Query: 481 DIGSGEIKL-GNDNIRDFNLRKYRRLLGVVQQEPMLFSG-TILDNITYAVPQELVNDETR 538
SG + G D + + + R+ +G Q LF T+ +++ + V D R
Sbjct: 1471 TPTSGTAFIFGKDIVA--SPKAIRQHIGYCPQFDALFEYLTVKEHLELYARIKGVVDH-R 1527
Query: 539 ISRAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILILDEATS 598
I + T+ L F D L+ + P T LSGG K+++++A A + DP I+ILDE ++
Sbjct: 1528 IDNVV-----TEKLVEF-DLLKHSHKPSFT-LSGGNKRKLSVAIAMIGDPPIVILDEPST 1580
Query: 599 ALDSQSEEVVAQSLQQRSAR-GKTTI 623
+D ++ + + + S R GKT +
Sbjct: 1581 GMDPVAKRFMWDVISRLSTRSGKTAV 1606
>YDR406w [Q] KOG0065 Pleiotropic drug resistance proteins (PDR1-15) ABC
superfamily
Length = 1529
Score = 58.2 bits (139), Expect = 4e-08
Identities = 56/234 (23%), Positives = 110/234 (46%), Gaps = 20/234 (8%)
Query: 429 HFNHVKFSYPTRP-QHHIFEDLNFTVRPGEHVCIVGPSGGGKSTVASLLLRYYDIG--SG 485
H+ + + P + Q I +++ V+PG ++G SG GK+T+ L +G +G
Sbjct: 885 HWRDLCYDVPIKGGQRRILNNVDGWVKPGTLTALMGASGAGKTTLLDCLAERVTMGVITG 944
Query: 486 EIKLGNDNIRDFNLRKYRRLLGVVQQEPM-LFSGTILDNITYAV----PQELVNDETRIS 540
I + + +RD + R +G QQ+ + L + T+ +++ ++ P + +E +
Sbjct: 945 NIFV-DGRLRD---ESFPRSIGYCQQQDLHLKTATVRESLRFSAYLRQPSSVSIEEK--N 998
Query: 541 RAIGQANCTKFLANFPDGLQTTVGPRGTQLSGGQKQRIALARAFLLDPSILI-LDEATSA 599
R + + + + D + VG G L+ Q++R+ + P +L+ LDE TS
Sbjct: 999 RYVEEVIKILEMQQYSDAV---VGVAGEGLNVEQRKRLTIGVELAARPKLLVFLDEPTSG 1055
Query: 600 LDSQSEEVVAQSLQQRSARGKTTISIAHRVSTI--QHSSRVIVLNRHGTVAETG 651
LDSQ+ Q +++ + G+ + H+ S I Q R++ L + G G
Sbjct: 1056 LDSQTAWDTCQLMRKLATHGQAILCTIHQPSAILMQQFDRLLFLQKGGQTVYFG 1109
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.136 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,052,365
Number of Sequences: 60738
Number of extensions: 1259175
Number of successful extensions: 5330
Number of sequences better than 1.0e-05: 289
Number of HSP's better than 0.0 without gapping: 176
Number of HSP's successfully gapped in prelim test: 113
Number of HSP's that attempted gapping in prelim test: 4065
Number of HSP's gapped (non-prelim): 537
length of query: 706
length of database: 30,389,216
effective HSP length: 113
effective length of query: 593
effective length of database: 23,525,822
effective search space: 13950812446
effective search space used: 13950812446
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)