ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0531 good C KOG0069 Energy production and conversion Glyoxylate/hydroxypyruvate reductase (D-isomer-specific 2-hydroxy acid dehydrogenase superfamily)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0531 177619 176573 -349
(349 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL274c [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isom... 440 e-123
SPACUNK4.10 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-... 243 2e-64
SPBC1773.17c [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D... 137 2e-32
At2g45630 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-is... 127 3e-29
7298717 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isom... 125 1e-28
7298718 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isom... 121 1e-27
CE08497 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-... 118 1e-26
At1g79870 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-is... 114 2e-25
7296684 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isom... 113 5e-25
Hs6912396 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-is... 109 7e-24
Hs4557499 [K] KOG0067 Transcription factor CtBP 109 7e-24
Hs12746590 [K] KOG0067 Transcription factor CtBP 107 3e-23
7297831 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-... 107 3e-23
Hs4557497 [K] KOG0067 Transcription factor CtBP 105 8e-23
At1g12550 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-is... 105 1e-22
At5g14780 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-is... 103 4e-22
7299709 [K] KOG0067 Transcription factor CtBP 103 4e-22
Hs5729974 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isome... 100 5e-21
Hs14744596 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isom... 100 5e-21
YOR388c [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isom... 98 2e-20
At3g19480 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isome... 97 4e-20
At1g17740 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isome... 97 4e-20
At4g34200 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isome... 96 8e-20
SPAC186.07c [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-iso... 90 4e-18
At1g68010 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-is... 86 6e-17
YPL113c [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isom... 86 8e-17
YIL074c [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-... 84 2e-16
YER081w [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-... 84 2e-16
YPL275w [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isom... 82 9e-16
SPCC4G3.01 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isom... 82 2e-15
SPAC186.02c [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-iso... 80 6e-15
CE28436 [K] KOG0067 Transcription factor CtBP 78 2e-14
Hs20557095 [K] KOG0067 Transcription factor CtBP 69 8e-12
Hs20545061 [K] KOG0067 Transcription factor CtBP 69 1e-11
At1g72190 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-is... 68 2e-11
YGL185c [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isom... 64 3e-10
Hs22060587 [K] KOG0067 Transcription factor CtBP 50 6e-06
>YNL274c [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 350
Score = 440 bits (1132), Expect = e-123
Identities = 213/347 (61%), Positives = 266/347 (76%)
Query: 3 KPVVLRLGQVKYAQKAWEELSKIAQVIPIDPSLTRAQFLDQCQDPESPISKAQILTRTFP 62
KP+VL+LG+ + +AW EL KIA VI I S TR QFL + +DP++ +S+ Q++TRT
Sbjct: 4 KPIVLKLGKDAFGDQAWGELEKIADVITIPESTTREQFLREVKDPQNKLSQVQVITRTAR 63
Query: 63 SVKNTGRFDAELAKALPESVVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTH 122
SVKNTGRFD ELA ALP SVVA+CH GAGYDQID PF +RHIQ++NVP+LV+N+TADTH
Sbjct: 64 SVKNTGRFDEELALALPSSVVAVCHTGAGYDQIDVEPFKKRHIQVANVPDLVSNATADTH 123
Query: 123 VFLLLGALRNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLK 182
VFLLLGALRNF G+R + EG WP P G+DPE R I+ERLK
Sbjct: 124 VFLLLGALRNFGIGNRRLIEGNWPEAGPACGSPFGYDPEGKTVGILGLGRIGRCILERLK 183
Query: 183 PFGFKKFIYHNRNRLSSDLENGCEYVSFEELLSQSDVISINIPLNAATRHMIDKEAISKM 242
PFGF+ FIYHNR++L S+ E+GCEYV FEE L +SD++S+N+PLN T H+I+ E I KM
Sbjct: 184 PFGFENFIYHNRHQLPSEEEHGCEYVGFEEFLKRSDIVSVNVPLNHNTHHLINAETIEKM 243
Query: 243 KDGVVIVNTARGAVIDEPALISALKSGKVRSAGLDVYENEPQVPQELLDLPNFIGVPHMG 302
KDGVVIVNTARGAVIDE A+ AL+SGK+RSAGLDV+E EP++ +ELL + +G+PHMG
Sbjct: 244 KDGVVIVNTARGAVIDEQAMTDALRSGKIRSAGLDVFEYEPKISKELLSMSQVLGLPHMG 303
Query: 303 THTVETIQKMEEFVVENVKSVINTGKVLTVIPELKKEGWINEAKPLV 349
TH+VET +KMEE VVEN K+VI TGKVLT++PEL+ E W NE+KPLV
Sbjct: 304 THSVETRKKMEELVVENAKNVILTGKVLTIVPELQNEDWPNESKPLV 350
>SPACUNK4.10 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 334
Score = 243 bits (621), Expect = 2e-64
Identities = 139/333 (41%), Positives = 196/333 (58%), Gaps = 10/333 (3%)
Query: 3 KPVVLRLGQVKYAQKAWEELSKIAQVIPIDPSLTRAQFLDQCQDPESPISKAQILTRTFP 62
KP L +G +K+A K WE L K A++ TR FL +C+ + + + RT+
Sbjct: 6 KPAALLVGTLKHAHKEWEALGKYAELKTYSDG-TREDFLAKCK---TEFQNVKAICRTYN 61
Query: 63 SVKNTGRFDAELAKALPESVVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTH 122
S G FD E+ LP SV ICH GAGY+ +D R IQ+S+VP+ V+++TAD
Sbjct: 62 SKFYMGIFDKEIIDNLPPSVKFICHLGAGYETVDVAACTARGIQVSHVPKAVDDATADVG 121
Query: 123 VFLLLGALRNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLK 182
+FL+LGALR F G + + W + HDPE + + +R +
Sbjct: 122 IFLMLGALRGFNQGIFELHKNNWNANCKPS-----HDPEGKTLGILGLGGIGKTMAKRAR 176
Query: 183 PFGFKKFIYHNRNRLSSDLENGCEYVSFEELLSQSDVISINIPLNAATRHMIDKEAISKM 242
F K +YHNR L + G E+VSF++LL++SDV+S+N+PLNA TRH+I K KM
Sbjct: 177 AFDMK-IVYHNRTPLPEEEAEGAEFVSFDDLLAKSDVLSLNLPLNAHTRHIIGKPEFQKM 235
Query: 243 KDGVVIVNTARGAVIDEPALISALKSGKVRSAGLDVYENEPQVPQELLDLPNFIGVPHMG 302
K G+VIVNTARGAV+DE AL+ AL G V SAGLDV+E EP++ LL+ I +PH+G
Sbjct: 236 KRGIVIVNTARGAVMDEAALVEALDEGIVYSAGLDVFEEEPKIHPGLLENEKVILLPHLG 295
Query: 303 THTVETIQKMEEFVVENVKSVINTGKVLTVIPE 335
T+++ET KME V+ NVK+ I + ++PE
Sbjct: 296 TNSLETQYKMECAVLMNVKNGIVNDSLPNLVPE 328
>SPBC1773.17c [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 185
Score = 137 bits (345), Expect = 2e-32
Identities = 73/155 (47%), Positives = 102/155 (65%), Gaps = 3/155 (1%)
Query: 175 RAIIERLKPFGFKKFIYHNRNRLSSDLEN--GCEYVSFEELLSQSDVISINIPLNAATRH 232
++ +++ P G + +YHNRNRL ++ E G +VSF+ELLS SDVISIN PL AT
Sbjct: 17 KSFAQKILPLGCE-IVYHNRNRLEAEEEKRLGASFVSFDELLSSSDVISINCPLTPATHD 75
Query: 233 MIDKEAISKMKDGVVIVNTARGAVIDEPALISALKSGKVRSAGLDVYENEPQVPQELLDL 292
+I + KMKDGV I+NTARGA+I+E A I A+KSGKV AGLDV+ NEP + L+
Sbjct: 76 LISTKEFEKMKDGVYIINTARGAIINEDAFIKAIKSGKVARAGLDVFLNEPTPNKFWLEC 135
Query: 293 PNFIGVPHMGTHTVETIQKMEEFVVENVKSVINTG 327
PH G +T T+ K EE V+ ++++ ++TG
Sbjct: 136 DKVTIQPHCGVYTNFTVAKTEECVLASIETFLDTG 170
>At2g45630 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 327
Score = 127 bits (318), Expect = 3e-29
Identities = 80/262 (30%), Positives = 131/262 (49%), Gaps = 6/262 (2%)
Query: 72 AELAKALPESVVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGALR 131
A+L + LP + + AG D +D +R I ++N + ADT V LL+ R
Sbjct: 71 ADLIRILPNLRLVVT-TSAGVDHVDLVECRRRGISVANAGSSFSEDVADTAVGLLIDVFR 129
Query: 132 NFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFKKFIY 191
+R +++ WP P+G + RL FG + Y
Sbjct: 130 RISAANRFVKQRFWP---LKGDYPLGSKLGRKRIGIVGLGSIGSKVATRLDAFGCQ-ISY 185
Query: 192 HNRNRLSSDLENGCEYVSFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNT 251
+RNR D+ Y+ EE+ + SD + I LN T +I+K+ +S + VIVN
Sbjct: 186 SSRNRKPYDVPYHY-YMDIEEMAANSDALIICCELNEKTLRLINKDVLSALGKRGVIVNV 244
Query: 252 ARGAVIDEPALISALKSGKVRSAGLDVYENEPQVPQELLDLPNFIGVPHMGTHTVETIQK 311
ARGA+IDE ++ L+ G++ AGLDV+E+EP VP+EL +L N + PH T+E +++
Sbjct: 245 ARGAIIDEEEMVRCLREGEIGGAGLDVFEDEPNVPKELFELDNVVFSPHSAFMTLEGLEE 304
Query: 312 MEEFVVENVKSVINTGKVLTVI 333
+ + VV N+++ + +LT +
Sbjct: 305 LGKVVVGNIEAFFSNKPLLTPV 326
>7298717 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 248
Score = 125 bits (313), Expect = 1e-28
Identities = 76/234 (32%), Positives = 119/234 (50%), Gaps = 5/234 (2%)
Query: 90 AGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGALRNFEYGHRLMEEGKWPSXX 149
AG D +D +R I + + P ++N + AD V LL+ A R F G + ++ KW +
Sbjct: 3 AGIDYVDVPEVKRRKIPLGHTPTVLNTAVADLAVGLLIAASRRFHEGRKTIDNDKWENYH 62
Query: 150 XXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFKKFIYHNRNRLSSDLEN--GCEY 207
+G D +AI +RL F K +Y R R+ ++E +
Sbjct: 63 LNWL--LGQDIRDSTVGFYGFGGIGQAIAKRLSGFDIDKVLYTTRRRVHKEIEEEFNAKK 120
Query: 208 VSFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALK 267
V F+ LL++SD + I PL T+ + + A +KMK V+VN ARG ++++ L ALK
Sbjct: 121 VDFDTLLAESDFVVIASPLTKDTQGVFNATAFNKMKQTAVLVNIARGKIVNQDDLYEALK 180
Query: 268 SGKVRSAGLDVYENEPQVPQE-LLDLPNFIGVPHMGTHTVETIQKMEEFVVENV 320
+ ++ SAGLDV + EP P++ LL L N + +PH+G+ T T M NV
Sbjct: 181 ANRIFSAGLDVTDPEPLSPKDKLLTLDNVVVLPHIGSATKRTRADMSTIAAHNV 234
>7298718 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 598
Score = 121 bits (304), Expect = 1e-27
Identities = 75/241 (31%), Positives = 120/241 (49%), Gaps = 5/241 (2%)
Query: 71 DAELAKALPESVVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGAL 130
+AE+ A + A+ +G + +D +R I + + P ++ + AD V LL+ A
Sbjct: 334 NAEILDAAGPQLKAVSTMSSGINNVDVPELKKRGIPLGSTPAMLTVAVADLTVGLLIAAA 393
Query: 131 RNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFKKFI 190
R F+ G R ++ KW +G D +A+ +RL F K+ +
Sbjct: 394 RRFQEGRRKIDSDKWDKDHLNWM--LGQDIRDSTVGFYGFGGIGQAVAKRLMGFDIKRML 451
Query: 191 YHNRNRLSSDLEN--GCEYVSFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVI 248
Y RNR+S D+E + V FE LL++SD + I PL T + + +KMK+ V+
Sbjct: 452 YTTRNRVSQDIEERFNAKKVDFETLLAESDFLIIASPLTKETLGLFNATVFNKMKETAVL 511
Query: 249 VNTARGAVIDEPALISALKSGKVRSAGLDVYENEPQVPQE-LLDLPNFIGVPHMGTHTVE 307
VN RG ++++ L ALKS ++ +AGLDV + EP + LL L N + PH+G T
Sbjct: 512 VNVGRGKIVNQDDLYEALKSNRIFAAGLDVMDPEPLPSNDKLLTLDNVVVTPHVGYATRR 571
Query: 308 T 308
T
Sbjct: 572 T 572
Score = 90.5 bits (223), Expect = 3e-18
Identities = 70/250 (28%), Positives = 110/250 (44%), Gaps = 23/250 (9%)
Query: 90 AGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGALRNFEYGHRLMEEGKWPSXX 149
+G D +D F +R I + + P +V N+ AD + L++ A R+F G +E +W
Sbjct: 83 SGIDFVDIPEFQKRGIPLGHTPGVVKNAVADLAIGLMIAAGRHFHAGRTEIERSQWKIEQ 142
Query: 150 XXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFKKFIYHNRNRLSSDLENGCEYVS 209
+G + +AI +RL+ + K IYH R R +D + E+VS
Sbjct: 143 INWM--MGQEIRDSVIGFFGFGGISQAIAKRLQCWDVAKIIYHTRTRKENDGDFKAEHVS 200
Query: 210 FEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALKSG 269
FE+LL +SD + + PL TR + +A + MK V VN ARG
Sbjct: 201 FEQLLQESDFLVVAAPLTNETREKFNGKAFNLMKRSSVFVNVARG--------------- 245
Query: 270 KVRSAGLDVYENEP-QVPQELLDLPNFIGVPHMGTHTVETIQKMEEFVVENVKSVINTGK 328
GLDV EP LL++PN G+ T + + + E ++ + +
Sbjct: 246 -----GLDVTTPEPLPANSPLLNVPNCEGLKMSTTKPFKVLIAHTDVPPEGIEILKEQCE 300
Query: 329 VLTVIPELKK 338
+L VI E K
Sbjct: 301 ILQVINEPPK 310
>CE08497 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-specific
2-hydroxy acid dehydrogenase superfamily
Length = 322
Score = 118 bits (296), Expect = 1e-26
Identities = 73/270 (27%), Positives = 124/270 (45%), Gaps = 6/270 (2%)
Query: 64 VKNTGRFDAELAKALPESVVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHV 123
V++ + AEL A + + G G D ID I + N P+ + S A+
Sbjct: 52 VRSATKITAELLAASAGKLKLVGRAGTGVDNIDVPAASANKILVMNTPQANSRSAAELTC 111
Query: 124 FLLLGALRNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKP 183
L+L R+ M+ GKW +G + + RL+
Sbjct: 112 TLILSLSRHVPQAAASMKAGKWARKDF-----MGEEVYGRTLAVLGLGRIGSEVAVRLQA 166
Query: 184 FGFKKFIYHNRNRLSSDLENGCEYVSFEELLSQSDVISINIPLNAATRHMIDKEAISKMK 243
FG K + E +S E++ Q+D I++++PL T ++I+KE ++K K
Sbjct: 167 FGMKVIGFDPMVTKEQAEAKNIELLSLEQIWPQADYITVHVPLIKQTENLINKETLAKCK 226
Query: 244 DGVVIVNTARGAVIDEPALISALKSGKVRSAGLDVYENEPQVPQELLDLPNFIGVPHMGT 303
GV I+N ARG +++E L+ +L +G + A DV+E EP +EL+D P I PH+G
Sbjct: 227 KGVRIINVARGGIVNEVDLVESLNAGHAKGAAFDVFEQEPPTFRELIDHPLVIATPHLGA 286
Query: 304 HTVETIQKMEEFVVENVKSVINTGKVLTVI 333
T++ ++ + +N+ N G +L V+
Sbjct: 287 STIDAQLRVASEIADNIVQ-YNKGTMLGVL 315
>At1g79870 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 313
Score = 114 bits (286), Expect = 2e-25
Identities = 76/263 (28%), Positives = 126/263 (47%), Gaps = 8/263 (3%)
Query: 71 DAELAKALPESVVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGAL 130
DA+L LP + + G D+ID ++ I+++N P+++ AD + L+L L
Sbjct: 58 DAQLISDLPNLEI-VSSFSVGLDKIDLGKCKEKGIRVTNTPDVLTEDVADLAIGLILALL 116
Query: 131 RNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFKKFI 190
R R + GKW AI +R + F
Sbjct: 117 RRLCECDRYVRSGKWKQGEFQLTTKFS----GKSVGIIGLGRIGTAIAKRAEAFSCP-IN 171
Query: 191 YHNRNRLSSDLENGCEYVSFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVN 250
Y++R + D+ Y + +L SD++ + PL TRH++D++ + + V++N
Sbjct: 172 YYSRT-IKPDVAYKY-YPTVVDLAQNSDILVVACPLTEQTRHIVDRQVMDALGAKGVLIN 229
Query: 251 TARGAVIDEPALISALKSGKVRSAGLDVYENEPQVPQELLDLPNFIGVPHMGTHTVETIQ 310
RG +DE LI AL G++ A LDV+E EP VP+EL L N + +PH+G+ TVET
Sbjct: 230 IGRGPHVDEQELIKALTEGRLGGAALDVFEQEPHVPEELFGLENVVLLPHVGSGTVETRN 289
Query: 311 KMEEFVVENVKSVINTGKVLTVI 333
M + VV N+++ + +LT +
Sbjct: 290 AMADLVVGNLEAHFSGKSLLTPV 312
>7296684 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 325
Score = 113 bits (282), Expect = 5e-25
Identities = 73/269 (27%), Positives = 127/269 (47%), Gaps = 4/269 (1%)
Query: 67 TGRFDAELAKALPESVVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLL 126
T + D E+ A + + GYD ID +R I++ P+++ ++TA+ + LL
Sbjct: 57 TDKVDKEVLDAAGPQLKCVATISVGYDHIDVEECRKRGIRVGFTPDVLTDATAELTLALL 116
Query: 127 LGALRNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGF 186
L R ++ + G W S G + + I R+ PF
Sbjct: 117 LATNRRLFEANKQVYNGGWKSWAPMWM--CGQGLKGSRVGLLGFGRIGQEIAARIVPFKP 174
Query: 187 KKFIYHNRN-RLSSDLENGCEYVSFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDG 245
+ Y R+ R +V F+E+L +SD+I + L T+ + + A KMK
Sbjct: 175 TEITYTTRSLRPKEAAAVNARHVDFDEMLRESDLIVVCCALTPETKEIFNATAFQKMKPN 234
Query: 246 VVIVNTARGAVIDEPALISALKSGKVRSAGLDVYENEP-QVPQELLDLPNFIGVPHMGTH 304
+++NTARG V+D+ AL ALK+ ++ +AGLDV EP + LL L N + +PH+G+
Sbjct: 235 CILINTARGGVVDQKALYEALKTKRILAAGLDVTTPEPLPIDDPLLKLDNVVILPHIGSA 294
Query: 305 TVETIQKMEEFVVENVKSVINTGKVLTVI 333
+ET ++M N+ + + K++ +
Sbjct: 295 DIETRKEMSRITARNILAALAGDKMVAEV 323
>Hs6912396 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 328
Score = 109 bits (272), Expect = 7e-24
Identities = 77/252 (30%), Positives = 116/252 (45%), Gaps = 4/252 (1%)
Query: 71 DAELAKALPESVVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGAL 130
D + A ++ I G D + +R I++ P+++ ++TA+ V LLL
Sbjct: 64 DKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTC 123
Query: 131 RNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFKKFI 190
R ++ G W S G+ +AI RLKPFG ++F+
Sbjct: 124 RRLPEAIEEVKNGGWTSWKPLWL--CGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFL 181
Query: 191 YHNRN-RLSSDLENGCEYVSFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIV 249
Y R R E E+VS EL +QSD I + L AT + +K+ KMK+ V +
Sbjct: 182 YTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFI 241
Query: 250 NTARGAVIDEPALISALKSGKVRSAGLDVYENEP-QVPQELLDLPNFIGVPHMGTHTVET 308
N +RG V+++ L AL SGK+ +AGLDV EP LL L N + +PH+G+ T T
Sbjct: 242 NISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRT 301
Query: 309 IQKMEEFVVENV 320
M N+
Sbjct: 302 RNTMSLLAANNL 313
>Hs4557499 [K] KOG0067 Transcription factor CtBP
Length = 445
Score = 109 bits (272), Expect = 7e-24
Identities = 80/268 (29%), Positives = 122/268 (44%), Gaps = 14/268 (5%)
Query: 69 RFDAELAKALPESVVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLG 128
R D E KAL I G+GYD +D G+ I + N+P TAD+ + +L
Sbjct: 89 REDLEKFKALR----VIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILN 144
Query: 129 ALRNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXX--XXRAIIERLKPFGF 186
R + ++ + EG +A+ R K FGF
Sbjct: 145 LYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGF 204
Query: 187 KKFIYHNRNRLSSDLENGCEYV-SFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDG 245
Y + + G + V + ++LL QSD +S++ LN H+I+ I +M+ G
Sbjct: 205 SVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQG 264
Query: 246 VVIVNTARGAVIDEPALISALKSGKVRSAGLDVYENEP----QVPQELLDLPNFIGVPHM 301
+VN ARG ++DE AL ALK G++R A LDV+E+EP Q P L D PN I PH
Sbjct: 265 AFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGP--LKDAPNLICTPHT 322
Query: 302 GTHTVETIQKMEEFVVENVKSVINTGKV 329
++ + +M E ++ I TG++
Sbjct: 323 AWYSEQASLEMREAAATEIRRAI-TGRI 349
>Hs12746590 [K] KOG0067 Transcription factor CtBP
Length = 985
Score = 107 bits (267), Expect = 3e-23
Identities = 79/268 (29%), Positives = 122/268 (45%), Gaps = 14/268 (5%)
Query: 69 RFDAELAKALPESVVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLG 128
R D E KAL I G+GYD ++ G+ I + N+P TAD+ + +L
Sbjct: 629 REDLEKFKALR----VIVRIGSGYDNVNIKAAGELGIAVCNIPSAAVEETADSTICHILN 684
Query: 129 ALRNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXX--XXRAIIERLKPFGF 186
R + ++ + EG +A+ R K FGF
Sbjct: 685 LYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGF 744
Query: 187 KKFIYHNRNRLSSDLENGCEYV-SFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDG 245
Y + + G + V + ++LL QSD +S++ LN H+I+ I +M+ G
Sbjct: 745 SVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQG 804
Query: 246 VVIVNTARGAVIDEPALISALKSGKVRSAGLDVYENEP----QVPQELLDLPNFIGVPHM 301
+VN ARG ++DE AL ALK G++R A LDV+E+EP Q P L D PN I PH
Sbjct: 805 AFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGP--LKDAPNLICTPHT 862
Query: 302 GTHTVETIQKMEEFVVENVKSVINTGKV 329
++ + +M E ++ I TG++
Sbjct: 863 AWYSEQASLEMREAAATEIRRAI-TGRI 889
>7297831 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-specific
2-hydroxy acid dehydrogenase superfamily
Length = 332
Score = 107 bits (266), Expect = 3e-23
Identities = 74/264 (28%), Positives = 119/264 (45%), Gaps = 13/264 (4%)
Query: 64 VKNTGRFDAELAKALPESVVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHV 123
V++ + AE+ A S+ + GAG D ID +++ + N P + S +
Sbjct: 52 VRSDTKITAEVLAAGSGSLKVVGRAGAGVDNIDVPAATAQNVVVLNTPGGNSISACELTC 111
Query: 124 FLLLGALRNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKP 183
L+ R + M+EG+W G R + R+K
Sbjct: 112 ILIGSLARPVVPAGQSMKEGRWDRKLYAGTELYGK-----TLAVLGLGRIGREVAIRMKT 166
Query: 184 FGFKKFIYHNRNRLSSDLENGCEYVSFEELLSQSDVISINIPLNAATRHMIDKEAISKMK 243
+G + Y + G E ++ EE+ +D I+++ PL ATR++I E ++K K
Sbjct: 167 WGMRIIGYDPITTEAEAKAAGIEKMTLEEIWPLADYITVHTPLIPATRNLISAETLAKCK 226
Query: 244 DGVVIVNTARGAVIDEPALISALKSGKVRSAGLDVYENEP---QVPQELLDLPNFIGVPH 300
GV +VN ARG +IDE A++ L+SGKV A DVY EP V + L+ P + PH
Sbjct: 227 QGVKVVNVARGGIIDEQAVLDGLESGKVAGAAFDVYPEEPPKSAVTKALISHPKVVATPH 286
Query: 301 MGTHTVE-----TIQKMEEFVVEN 319
+G T E ++ E+F+ N
Sbjct: 287 LGASTSEAQVRVAVEVAEQFIALN 310
>Hs4557497 [K] KOG0067 Transcription factor CtBP
Length = 440
Score = 105 bits (263), Expect = 8e-23
Identities = 84/270 (31%), Positives = 123/270 (45%), Gaps = 18/270 (6%)
Query: 69 RFDAELAKALPESVVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLG 128
R D E KAL I G+G+D ID G I + NVP TAD+ + +L
Sbjct: 83 REDLEKFKALR----IIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILN 138
Query: 129 ALRNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXXXX--RAIIERLKPFGF 186
R + H+ + EG +A+ R K FGF
Sbjct: 139 LYRRATWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGF 198
Query: 187 KKFIYHNRNRLSSDLEN--GCEYVS-FEELLSQSDVISINIPLNAATRHMIDKEAISKMK 243
Y LS +E G + VS ++LL SD ++++ LN H+I+ + +M+
Sbjct: 199 NVLFYDPY--LSDGVERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMR 256
Query: 244 DGVVIVNTARGAVIDEPALISALKSGKVRSAGLDVYENEP----QVPQELLDLPNFIGVP 299
G +VNTARG ++DE AL ALK G++R A LDV+E+EP Q P L D PN I P
Sbjct: 257 QGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGP--LKDAPNLICTP 314
Query: 300 HMGTHTVETIQKMEEFVVENVKSVINTGKV 329
H ++ + +M E ++ I TG++
Sbjct: 315 HAAWYSEQASIEMREEAAREIRRAI-TGRI 343
>At1g12550 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 323
Score = 105 bits (262), Expect = 1e-22
Identities = 76/265 (28%), Positives = 121/265 (44%), Gaps = 15/265 (5%)
Query: 73 ELAKALPESVVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGALRN 132
EL LP + +C G D ID +R I I+N ++ AD V LL+ LR
Sbjct: 67 ELLSHLPSLQILVC-TSVGIDHIDLAACKRRGIVITNAGNAFSDDVADCAVGLLISVLRR 125
Query: 133 FEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFKKFIYH 192
R + G W +G + +RL+ FG Y+
Sbjct: 126 IPAADRYVRSGNWAKFGDFQ---LGSKVSGKRVGIVGLGSIGSFVAKRLESFGCV-ISYN 181
Query: 193 NRNRLSSDLENGCEYVSFEELLS---QSDVISINIPLNAATRHMIDKEAISKM-KDGVVI 248
+R++ S Y + ++LS +DV+ + L T H++++E + + KDGVVI
Sbjct: 182 SRSQKQSS-----PYRYYSDILSLAENNDVLVLCCSLTDETHHIVNREVMELLGKDGVVI 236
Query: 249 VNTARGAVIDEPALISALKSGKVRSAGLDVYENEPQVPQELLDLPNFIGVPHMGTHTVET 308
N RG +IDE ++ L G + AGLDV+ENEP VPQEL L N + PH T +
Sbjct: 237 -NVGRGKLIDEKEMVKCLVDGVIGGAGLDVFENEPAVPQELFGLDNVVLSPHFAVATPGS 295
Query: 309 IQKMEEFVVENVKSVINTGKVLTVI 333
+ + + + N+K+ + +L+ +
Sbjct: 296 LDNVAQIALANLKAFFSNRPLLSPV 320
>At5g14780 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 384
Score = 103 bits (257), Expect = 4e-22
Identities = 69/224 (30%), Positives = 115/224 (50%), Gaps = 10/224 (4%)
Query: 89 GAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGALRNFEYGHRLMEEGKWPSX 148
G G D ID + ++ V S A+ + +L +RNF G+ + +G+W
Sbjct: 127 GIGSDHIDLQAAAAAGLTVAEVTGSNVVSVAEDELMRILILMRNFVPGYNQVVKGEWNVA 186
Query: 149 XXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFKKFIYHNRNRLSSDLEN--GCE 206
+D E + +++RLKPFG +YH+R +++ +LE G +
Sbjct: 187 GIAYRA---YDLEGKTIGTVGAGRIGKLLLQRLKPFGCN-LLYHDRLQMAPELEKETGAK 242
Query: 207 YVS-FEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISA 265
+V E+L + DVI IN+PL TR M +KE I K+K GV+IVN ARGA+++ A++ A
Sbjct: 243 FVEDLNEMLPKCDVIVINMPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQAVVDA 302
Query: 266 LKSGKVRSAGLDVYENEPQVPQE--LLDLPNFIGVPHMGTHTVE 307
++SG + DV++ +P P++ +PN PH T++
Sbjct: 303 VESGHIGGYSGDVWDPQP-APKDHPWRYMPNQAMTPHTSGTTID 345
>7299709 [K] KOG0067 Transcription factor CtBP
Length = 386
Score = 103 bits (257), Expect = 4e-22
Identities = 80/260 (30%), Positives = 114/260 (43%), Gaps = 11/260 (4%)
Query: 71 DAELAKALPESVVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGAL 130
D E KAL I G+G D ID G+ I + NVP ADT + L+L
Sbjct: 85 DLEKFKALR----IIVRIGSGTDNIDVKAAGELGIAVCNVPGYGVEEVADTTMCLILNLY 140
Query: 131 RNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXXXXR---AIIERLKPFGFK 187
R + ++ EGK H R A+ R K FGF
Sbjct: 141 RRTYWLANMVREGK-KFTGPEQVREAAHGCARIRGDTLGLVGLGRIGSAVALRAKAFGFN 199
Query: 188 KFIYHNRNRLSSDLENGCEYV-SFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGV 246
Y D G V + ++LL QSD +S++ LN H+I++ I +M+ G
Sbjct: 200 VIFYDPYLPDGIDKSLGLTRVYTLQDLLFQSDCVSLHCTLNEHNHHLINEFTIKQMRPGA 259
Query: 247 VIVNTARGAVIDEPALISALKSGKVRSAGLDVYENEPQ--VPQELLDLPNFIGVPHMGTH 304
+VNTARG ++D+ L ALK G++R+A LDV+ENEP L D PN I PH
Sbjct: 260 FLVNTARGGLVDDETLALALKQGRIRAAALDVHENEPYNVFQGALKDAPNLICTPHAAFF 319
Query: 305 TVETIQKMEEFVVENVKSVI 324
+ + ++ E ++ I
Sbjct: 320 SDASATELREMAATEIRRAI 339
>Hs5729974 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-specific
2-hydroxy acid dehydrogenase superfamily
Length = 533
Score = 99.8 bits (247), Expect = 5e-21
Identities = 78/299 (26%), Positives = 131/299 (43%), Gaps = 21/299 (7%)
Query: 34 SLTRAQFLDQCQDPESPISKAQILTRTFPSVKNTGRFDAELAKALPESVVAICHNGAGYD 93
+L++ + + + QD E I V++ + A++ A E + + G G D
Sbjct: 35 NLSKEELIAELQDCEGLI------------VRSATKVTADVINAA-EKLQVVGRAGTGVD 81
Query: 94 QIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGALRNFEYGHRLMEEGKWPSXXXXXX 153
+D ++ I + N P + S A+ +++ R M++GKW
Sbjct: 82 NVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKF--- 138
Query: 154 XPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFKKFIYHNRNRLSSDLENGCEYVSFEEL 213
+G + R + R++ FG K Y G + + EE+
Sbjct: 139 --MGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEI 196
Query: 214 LSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALKSGKVRS 273
D I+++ PL +T +++ ++ K GV +VN ARG ++DE AL+ AL+SG+
Sbjct: 197 WPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAG 256
Query: 274 AGLDVYENEPQVPQELLDLPNFIGVPHMGTHTVETIQKM-EEFVVENVKSVINTGKVLT 331
A LDV+ EP + L+D N I PH+G T E + EE V+ V V GK LT
Sbjct: 257 AALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMV--KGKSLT 313
>Hs14744596 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-specific
2-hydroxy acid dehydrogenase superfamily
Length = 533
Score = 99.8 bits (247), Expect = 5e-21
Identities = 78/299 (26%), Positives = 131/299 (43%), Gaps = 21/299 (7%)
Query: 34 SLTRAQFLDQCQDPESPISKAQILTRTFPSVKNTGRFDAELAKALPESVVAICHNGAGYD 93
+L++ + + + QD E I V++ + A++ A E + + G G D
Sbjct: 35 NLSKEELIAELQDCEGLI------------VRSATKVTADVINAA-EKLQVVGRAGTGVD 81
Query: 94 QIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGALRNFEYGHRLMEEGKWPSXXXXXX 153
+D ++ I + N P + S A+ +++ R M++GKW
Sbjct: 82 NVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKF--- 138
Query: 154 XPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFKKFIYHNRNRLSSDLENGCEYVSFEEL 213
+G + R + R++ FG K Y G + + EE+
Sbjct: 139 --MGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEI 196
Query: 214 LSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALKSGKVRS 273
D I+++ PL +T +++ ++ K GV +VN ARG ++DE AL+ AL+SG+
Sbjct: 197 WPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAG 256
Query: 274 AGLDVYENEPQVPQELLDLPNFIGVPHMGTHTVETIQKM-EEFVVENVKSVINTGKVLT 331
A LDV+ EP + L+D N I PH+G T E + EE V+ V V GK LT
Sbjct: 257 AALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMV--KGKSLT 313
>YOR388c [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 376
Score = 98.2 bits (243), Expect = 2e-20
Identities = 70/256 (27%), Positives = 118/256 (45%), Gaps = 22/256 (8%)
Query: 89 GAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGALRNFEYGHRLMEEGKWPSX 148
G G D +D +R I ++ V S A+ + +L +RN+ GH+ G+W
Sbjct: 96 GVGSDHVDLEAANERKITVTEVTGSNVVSVAEHVMATILVLIRNYNGGHQQAINGEWDIA 155
Query: 149 XXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFKKFIYHNRNRLSSDLENGCEYV 208
+D E ++ERL F KK +Y++ L ++ N
Sbjct: 156 GVAKNE---YDLEDKIISTVGAGRIGYRVLERLVAFNPKKLLYYDYQELPAEAINRLNEA 212
Query: 209 S---------------FEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTAR 253
S E++++QSDV++IN PL+ +R + +K+ IS MKDG +VNTAR
Sbjct: 213 SKLFNGRGDIVQRVEKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTAR 272
Query: 254 GAVIDEPALISALKSGKVRSAGLDVYENEP---QVPQELLDLPNFIGVPHMGTHTVETIQ 310
GA+ + A+KSGK+ G DV++ +P P +D + +G M H T
Sbjct: 273 GAICVAEDVAEAVKSGKLAGYGGDVWDKQPAPKDHPWRTMDNKDHVG-NAMTVHISGTSL 331
Query: 311 KMEEFVVENVKSVINT 326
++ + VK+++N+
Sbjct: 332 DAQKRYAQGVKNILNS 347
>At3g19480 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-specific
2-hydroxy acid dehydrogenase superfamily
Length = 588
Score = 97.1 bits (240), Expect = 4e-20
Identities = 79/264 (29%), Positives = 109/264 (40%), Gaps = 9/264 (3%)
Query: 89 GAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGALRNFEYGHRLMEEGKWPSX 148
G G D +D + + N P + A+ + LL RN ++ GKW
Sbjct: 117 GVGIDNVDLAAATEYGCLVVNAPTANTVAAAEHGIALLTAMARNIAQADASIKAGKWTRN 176
Query: 149 XXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFKKFIYHNRNRLSSDLENGCEYV 208
VG + R + G + G E V
Sbjct: 177 KYVGVSLVGK-----TLAVLGFGKVGSEVARRARGLGMHVITHDPYAPADRARAIGVELV 231
Query: 209 SFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALKS 268
SFE +S +D IS+++PL AAT M++ + MK GV IVN ARG VIDE AL+ AL S
Sbjct: 232 SFEVAISTADFISLHLPLTAATSKMMNDVTFAMMKKGVRIVNVARGGVIDEEALLRALDS 291
Query: 269 GKVRSAGLDVYENEPQVPQELLDLPNFI-GVPHMGTHTVETIQKMEEFVVENVKSVINTG 327
G V A LDV+ EP V L L + PH+G T+E + + V E V +
Sbjct: 292 GIVAQAALDVFTVEPPVKDNKLVLHESVTATPHLGASTMEAQEGVSIEVAEAVIGALRGE 351
Query: 328 KVLTVI--PELKKEGWINEAKPLV 349
T + P + E + E KP V
Sbjct: 352 LAATAVNAPMVPLE-VLRELKPYV 374
>At1g17740 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-specific
2-hydroxy acid dehydrogenase superfamily
Length = 624
Score = 97.1 bits (240), Expect = 4e-20
Identities = 69/262 (26%), Positives = 109/262 (41%), Gaps = 6/262 (2%)
Query: 64 VKNTGRFDAELAKALPESVVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHV 123
V++ + E+ +A + + G G D +D + + N P + A+ +
Sbjct: 128 VRSGTKVTREVFEAAKGRLKVVGRAGVGIDNVDLQAATEHGCLVVNAPTANTVAAAEHGI 187
Query: 124 FLLLGALRNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKP 183
LL RN ++ GKW VG + R K
Sbjct: 188 ALLASMARNVAQADASIKAGKWERSKYVGVSLVGK-----TLAVMGFGKVGTEVARRAKG 242
Query: 184 FGFKKFIYHNRNRLSSDLENGCEYVSFEELLSQSDVISINIPLNAATRHMIDKEAISKMK 243
G + G + VSF++ +S +D +S+++PL AT+ + + E SKMK
Sbjct: 243 LGMTVISHDPYAPADRARALGVDLVSFDQAISTADFVSLHMPLTPATKKVFNDETFSKMK 302
Query: 244 DGVVIVNTARGAVIDEPALISALKSGKVRSAGLDVY-ENEPQVPQELLDLPNFIGVPHMG 302
GV ++N ARG VIDE AL+ AL +G V A LDV+ E P L+ N PH+G
Sbjct: 303 KGVRLINVARGGVIDEDALVRALDAGIVAQAALDVFCEEPPSKDSRLIQHENVTVTPHLG 362
Query: 303 THTVETIQKMEEFVVENVKSVI 324
T E + + + E V +
Sbjct: 363 ASTKEAQEGVAIEIAEAVAGAL 384
>At4g34200 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-specific
2-hydroxy acid dehydrogenase superfamily
Length = 603
Score = 95.9 bits (237), Expect = 8e-20
Identities = 73/264 (27%), Positives = 112/264 (41%), Gaps = 9/264 (3%)
Query: 89 GAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGALRNFEYGHRLMEEGKWPSX 148
G G D +D + + + N P + A+ + L+ RN ++ G+W
Sbjct: 132 GVGIDNVDLSAATEFGCLVVNAPTANTIAAAEHGIALMAAMARNVAQADASVKAGEWKRN 191
Query: 149 XXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFKKFIYHNRNRLSSDLENGCEYV 208
VG + R K G + + G + V
Sbjct: 192 KYVGVSLVGK-----TLAVLGFGKVGTEVARRAKGLGMRVIAHDPYAPADRAHAIGVDLV 246
Query: 209 SFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALKS 268
SF+E L+ +D IS+++PL T +++ E +KMK GV IVN ARG VIDE AL+ AL +
Sbjct: 247 SFDEALATADFISLHMPLTPTTSKILNDETFAKMKKGVRIVNVARGGVIDEDALVRALDA 306
Query: 269 GKVRSAGLDVYENEPQV-PQELLDLPNFIGVPHMGTHTVETIQKMEEFVVENVKSVINTG 327
G V A LDV+ EP +L+ PH+G T+E + + + E V +N
Sbjct: 307 GIVAQAALDVFTKEPPAKDSKLVQHERVTVTPHLGASTMEAQEGVAIEIAEAVVGALNGE 366
Query: 328 KVLTVI--PELKKEGWINEAKPLV 349
T + P + E + E KP V
Sbjct: 367 LAATAVNAPMVSAE-VLTELKPYV 389
>SPAC186.07c [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-specific
2-hydroxy acid dehydrogenase superfamily
Length = 332
Score = 90.1 bits (222), Expect = 4e-18
Identities = 68/281 (24%), Positives = 126/281 (44%), Gaps = 22/281 (7%)
Query: 69 RFDAELAKALPES-VVAICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLL 127
+ DA+ K L ++ I AG++ +D I + VP + A+ + LLL
Sbjct: 55 KVDADTLKVLAKNGTKLIALRCAGFNNVDLKAAADNGITVVRVPAYSPYAVAEYTIGLLL 114
Query: 128 GALRNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFK 187
R + + E + +GHD + + LK GF
Sbjct: 115 SLNRKIHRAYVRVREDDFNLNGL-----LGHDLHGKTIGLLGTGRIGGLVAKCLK-LGFG 168
Query: 188 KFIYHNRNRLSSDLEN-GCEYVSFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGV 246
+ + + + +LE G ++V +E+L+++D + ++ PL T H++D++ ++ MK GV
Sbjct: 169 CEVLAHDIKPNKELEKFGIQFVEQQEVLAKADFLCLHCPLTPDTEHLVDEKLLASMKKGV 228
Query: 247 VIVNTARGAVIDEPALISALKSGKVRSAGLDVYENEPQV--------------PQELLDL 292
I+NT+RG ++D AL+ A++SG+V +DVYE E ++ Q+L +
Sbjct: 229 KIINTSRGGLVDTKALVKAIESGQVGGCAMDVYEGERRLFYRDLSNEVIKDTTFQQLANF 288
Query: 293 PNFIGVPHMGTHTVETIQKMEEFVVENVKSVINTGKVLTVI 333
PN + H T E + + ++NV + +VI
Sbjct: 289 PNVLVTSHQAFFTAEALSAIAHTTLKNVSDFASQNNDPSVI 329
>At1g68010 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 386
Score = 86.3 bits (212), Expect = 6e-17
Identities = 72/255 (28%), Positives = 112/255 (43%), Gaps = 21/255 (8%)
Query: 84 AICHNGAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGALRNFEYGHRLMEEG 143
A + GY+ +D + I + N P ++ +TA+ L L A R M G
Sbjct: 89 AFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRGG 148
Query: 144 KWPSXXXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFKKFIYHNRNRLSSDLE- 202
+ VG+ + A R+ GFK + + S+ LE
Sbjct: 149 LYEGWLPHLF--VGNLLKGQTVGVIGAGRIGSAYA-RMMVEGFKMNLIYFDLYQSTRLEK 205
Query: 203 -----------NGCEYV------SFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDG 245
NG + V S EE+L ++D+IS++ L+ T H+++KE ++ MK
Sbjct: 206 FVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKE 265
Query: 246 VVIVNTARGAVIDEPALISALKSGKVRSAGLDVYENEPQVPQELLDLPNFIGVPHMGTHT 305
++VN +RG VIDE AL+ LK + GLDV+E EP + L D N I VPH+ + +
Sbjct: 266 AILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASAS 325
Query: 306 VETIQKMEEFVVENV 320
T + M NV
Sbjct: 326 KWTREGMATLAALNV 340
>YPL113c [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 396
Score = 85.9 bits (211), Expect = 8e-17
Identities = 45/112 (40%), Positives = 72/112 (64%), Gaps = 1/112 (0%)
Query: 217 SDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALKSGKVRSAGL 276
+D+I + +P A+T ++I++++++ KDGV IVN RG IDE L+ AL+SGKV S GL
Sbjct: 277 ADLIILALPSTASTNNIINRKSLAWCKDGVRIVNVGRGTCIDEDVLLDALESGKVASCGL 336
Query: 277 DVYEN-EPQVPQELLDLPNFIGVPHMGTHTVETIQKMEEFVVENVKSVINTG 327
DV++N E +V QELL + +PH+G+ + + K +ENV+ + G
Sbjct: 337 DVFKNEETRVKQELLRRWDVTALPHIGSTVADMVIKQTLITLENVQDIFVEG 388
>YIL074c [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-specific
2-hydroxy acid dehydrogenase superfamily
Length = 469
Score = 84.3 bits (207), Expect = 2e-16
Identities = 45/132 (34%), Positives = 69/132 (52%), Gaps = 13/132 (9%)
Query: 209 SFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALKS 268
+ +ELL++SD +++++P T M+ + MKDG ++N +RG V+D P+LI A+K+
Sbjct: 243 TLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKA 302
Query: 269 GKVRSAGLDVYENEP-------------QVPQELLDLPNFIGVPHMGTHTVETIQKMEEF 315
K+ A LDVY +EP EL+ LPN I PH+G T E +
Sbjct: 303 NKIAGAALDVYPHEPAKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTEEAQSSIGIE 362
Query: 316 VVENVKSVINTG 327
V + IN G
Sbjct: 363 VATALSKYINEG 374
>YER081w [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-specific
2-hydroxy acid dehydrogenase superfamily
Length = 469
Score = 84.3 bits (207), Expect = 2e-16
Identities = 45/132 (34%), Positives = 69/132 (52%), Gaps = 13/132 (9%)
Query: 209 SFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALKS 268
+ +ELL++SD +++++P T M+ + MKDG ++N +RG V+D P+LI A+K+
Sbjct: 243 TLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKA 302
Query: 269 GKVRSAGLDVYENEP-------------QVPQELLDLPNFIGVPHMGTHTVETIQKMEEF 315
K+ A LDVY +EP EL+ LPN I PH+G T E +
Sbjct: 303 NKIAGAALDVYPHEPAKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTEEAQSSIGIE 362
Query: 316 VVENVKSVINTG 327
V + IN G
Sbjct: 363 VATALSKYINEG 374
>YPL275w [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 236
Score = 82.4 bits (202), Expect = 9e-16
Identities = 52/168 (30%), Positives = 88/168 (51%), Gaps = 19/168 (11%)
Query: 177 IIERLKPFGFKKFIYHNRNRLSSDLENGCEYVS---------------FEELLSQSDVIS 221
++ERL F KK +Y++ L ++ N S E++++QSDV++
Sbjct: 41 VLERLVAFNPKKLLYYDYQELPAEAINRLNEASKLFNGRGDIVQRVEKLEDMVAQSDVVT 100
Query: 222 INIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALKSGKVRSAGLDVYEN 281
IN PL+ +R + +K+ IS MKDG +VNTARGA+ + A+KSGK+ G DV++
Sbjct: 101 INCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDVAEAVKSGKLAGYGGDVWDK 160
Query: 282 EP---QVPQELLDLPNFIGVPHMGTHTVETIQKMEEFVVENVKSVINT 326
+P P +D + +G M H T ++ + VK+++N+
Sbjct: 161 QPAPKDHPWRTMDNKDHVG-NAMTVHISGTSLHAQKRYAQGVKNILNS 207
>SPCC4G3.01 [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-specific
2-hydroxy acid dehydrogenase superfamily
Length = 466
Score = 81.6 bits (200), Expect = 2e-15
Identities = 46/138 (33%), Positives = 71/138 (51%), Gaps = 13/138 (9%)
Query: 209 SFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALKS 268
S ELL ++D +S+++P + T++MI + + MK+G ++N +RG V+D PAL+ A KS
Sbjct: 240 SLPELLHRADFVSLHVPASPETKNMISSKEFAAMKEGSYLINASRGTVVDIPALVDASKS 299
Query: 269 GKVRSAGLDVYENEP-------------QVPQELLDLPNFIGVPHMGTHTVETIQKMEEF 315
GK+ A +DVY +EP EL N I PH+G T E +
Sbjct: 300 GKIAGAAIDVYPSEPAGNGKDKFVDSLNSWTSELTHCKNIILTPHIGGSTEEAQYNIGIE 359
Query: 316 VVENVKSVINTGKVLTVI 333
V E + IN G + +
Sbjct: 360 VSEALTRYINEGNSIGAV 377
>SPAC186.02c [E] KOG0068 D-3-phosphoglycerate dehydrogenase D-isomer-specific
2-hydroxy acid dehydrogenase superfamily
Length = 332
Score = 79.7 bits (195), Expect = 6e-15
Identities = 71/281 (25%), Positives = 120/281 (42%), Gaps = 27/281 (9%)
Query: 45 QDPESPISKAQILTRTFPSVKNTGRFDAELAKALPES-VVAICHNGAGYDQIDPTPFGQR 103
+D S KAQ++ V + DA+ KAL E+ V + GY+ ++ +
Sbjct: 36 KDTVSLAGKAQVVC-----VFVNDQVDADTLKALAENGVKLVALRCGGYNNVNLKAASEY 90
Query: 104 HIQISNVPELVNNSTADTHVFLLLGALRNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXX 163
I + +VP + ++ V LLL R + + E + +G D
Sbjct: 91 KITVVHVPSYSPFAVSEFTVGLLLSLNRKIHRAYVRVREDDFNIVGL-----LGCDIHGK 145
Query: 164 XXXXXXXXXXXRAIIERLKPFGFKKFIYHNRNRLSSDLEN-GCEYVSFEELLSQSDVISI 222
+ + K GF + LEN G ++V E+L ++D + +
Sbjct: 146 TVGVIGTGKIGSNVAKCFK-MGFGCDVLAYDINPDKKLENYGVQFVEQNEVLKKADFLCL 204
Query: 223 NIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALKSGKVRSAGLDVYENE 282
+ PL +T H+++ ++++ MK GV IVNT+RG +ID AL+ A+ SG+V +DVYE E
Sbjct: 205 HCPLTPSTTHIVNSDSLALMKKGVTIVNTSRGGLIDTKALVDAIDSGQVGGCAIDVYEGE 264
Query: 283 --------------PQVPQELLDLPNFIGVPHMGTHTVETI 309
Q L++ PN + H T E +
Sbjct: 265 RNLFYKDLSNEVIKDSTFQRLVNFPNVLVTSHQAFFTTEAL 305
>CE28436 [K] KOG0067 Transcription factor CtBP
Length = 701
Score = 78.2 bits (191), Expect = 2e-14
Identities = 68/266 (25%), Positives = 112/266 (41%), Gaps = 6/266 (2%)
Query: 89 GAGYDQIDPTPFGQRHIQISNVPELVNNSTADTHVFLLLGALRN-FEYGHRLMEEGKWPS 147
G G D ID + I + + P AD+ + L+L R + + E K
Sbjct: 224 GYGIDNIDVKAATELGIAVCHAPGDYVEDVADSTLSLILDLFRRTYWHAKSYSETRKTIG 283
Query: 148 XXXXXXXPVGHDP-EXXXXXXXXXXXXXRAIIERLKPFGFKKFIYHNRNRLSSDLENGCE 206
VG A+ R + FG Y R D G E
Sbjct: 284 ADQVRENAVGSKKVRGSVLGILGCGRVGTAVGLRARAFGLHIIFYDPFVREGHDKALGFE 343
Query: 207 YV-SFEELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISA 265
V + +E +S+SD IS++ L TR +I+ +++ + K GV IVNT+ +I+E L +A
Sbjct: 344 RVYTMDEFMSRSDCISLHCNLGDETRGIINADSLRQCKSGVYIVNTSHAGLINENDLAAA 403
Query: 266 LKSGKVRSAGLDVYEN---EPQVPQELLDLPNFIGVPHMGTHTVETIQKMEEFVVENVKS 322
LK+G V+ A LDV+++ +P L+ PN I PH T + + + + ++
Sbjct: 404 LKNGHVKGAALDVHDSVRFDPNCLNPLVGCPNIINTPHSAWMTEASCKDLRINAAKEIRK 463
Query: 323 VINTGKVLTVIPELKKEGWINEAKPL 348
IN + + KE + + P+
Sbjct: 464 AINGRCPQDLTHCINKEAVMRNSNPI 489
>Hs20557095 [K] KOG0067 Transcription factor CtBP
Length = 356
Score = 69.3 bits (168), Expect = 8e-12
Identities = 54/221 (24%), Positives = 90/221 (40%), Gaps = 9/221 (4%)
Query: 105 IQISNVPELVNNSTADTHVFLLLGALRNFEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXX 164
I + N+P TAD+ V +L R + + + EG W
Sbjct: 73 IVVCNIPSGALEETADSTVCDILNLYRRNTWVCQALREGTWVQSMEQILEVALGVVRIHA 132
Query: 165 XXXXXXXXXXRAIIERLKPFGFKKFIYHNRNRLSSDLENGCEYV-SFEELLSQSDVISIN 223
+A+ + K FGF Y + + G ++V + ++LL QS +S +
Sbjct: 133 VGLMSFGRTRQAVAFQAKAFGFSVIFYDPYLQDGIERSLGIQWVYTLQDLLYQSYCVSSH 192
Query: 224 IPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALKSGKVRSAGLDVYENEP 283
LN H+I+ I +M+ G ++N A G ++ E AL ALK G++ D + P
Sbjct: 193 CSLNEHNHHLINDFTIKQMRQGAFLLNAAPGGLVGEKALAQALKEGRITR---DSFAQGP 249
Query: 284 QVPQELLDLPNFIGVPHMGTHTVETIQKMEEFVVENVKSVI 324
L D PN I +PH ++ + +M E + I
Sbjct: 250 -----LKDAPNLICIPHTTWYSEQVSLEMREAAATEFRRAI 285
>Hs20545061 [K] KOG0067 Transcription factor CtBP
Length = 200
Score = 68.6 bits (166), Expect = 1e-11
Identities = 37/94 (39%), Positives = 53/94 (56%), Gaps = 6/94 (6%)
Query: 211 EELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALKSGK 270
E LL QSD +S++ LN H+++ I +M+ G +VN A G ++DE AL LK +
Sbjct: 107 EGLLYQSDCVSLHCNLNEHNHHLVNDFTIKQMRQGAFLVNAAHGGLVDEKALAQVLKEDR 166
Query: 271 VRSAGLDVYENEP----QVPQELLDLPNFIGVPH 300
+ A L ++E+EP Q P L D PN I PH
Sbjct: 167 IGGAALGLHESEPFSFAQTP--LKDAPNLIFTPH 198
>At1g72190 [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 344
Score = 67.8 bits (164), Expect = 2e-11
Identities = 63/251 (25%), Positives = 112/251 (44%), Gaps = 27/251 (10%)
Query: 81 SVVAICHNGAGYDQIDPTPFGQRHIQISNVP-ELVNN--STADTHVFLLLGALRN----- 132
++ I G G D +D + I+++ +P E N S ++ ++L+LG L+
Sbjct: 86 NIKLIMQYGVGLDGVDIDAATKHGIKVARIPSEGTGNAASCSEMAIYLMLGLLKKQNEMQ 145
Query: 133 FEYGHRLMEEGKWPSXXXXXXXPVGHDPEXXXXXXXXXXXXXRAIIERLKPFGFKKFI-- 190
+RL+ E P G + +RLKPFG +
Sbjct: 146 ISLRNRLLGE------------PTGDTLLGKTVFILGYGNIGIELAKRLKPFGSRVIATK 193
Query: 191 -YHNRNRLSSDLENGCEYVSFEELLS---QSDVISINIPLNAATRHMIDKEAISKMKDGV 246
+ + + SD E S E++ + ++D++ + + LN T +++KE I MK G
Sbjct: 194 RFWPASIVDSDSRLVDEKGSHEDIYTFAGKADIVVVCLRLNKETAEIVNKEFICSMKKGA 253
Query: 247 VIVNTARGAVIDEPALISALKSGKVRSAGLDVYENEPQVPQE-LLDLPNFIGVPHMGTHT 305
++VN ARG +I+ + L+SG + G+DV +EP P + +L N I PH+ T
Sbjct: 254 LLVNIARGGLINYESAFQNLESGHLGGLGIDVAWSEPFDPNDPILKFKNVIITPHVAGVT 313
Query: 306 VETIQKMEEFV 316
+ + M + V
Sbjct: 314 EYSYRSMAKIV 324
>YGL185c [C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific
2-hydroxy acid dehydrogenase superfamily)
Length = 379
Score = 64.3 bits (155), Expect = 3e-10
Identities = 29/113 (25%), Positives = 61/113 (53%), Gaps = 1/113 (0%)
Query: 214 LSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALKSGKVRS 273
L Q I + +P T H+I+++ + G+++VN RG ++D A+ AL +G++
Sbjct: 254 LYQFHAIVVTLPGTPQTEHLINRKFLEHCNPGLILVNLGRGKILDLRAVSDALVTGRINH 313
Query: 274 AGLDVYENEPQVPQELLDLPNFIGV-PHMGTHTVETIQKMEEFVVENVKSVIN 325
GLDV+ EP++ +++ + PH+G+ T + ++ E + + V++
Sbjct: 314 LGLDVFNKEPEIDEKIRSSDRLTSITPHLGSATKDVFEQSCELALTRILRVVS 366
>Hs22060587 [K] KOG0067 Transcription factor CtBP
Length = 356
Score = 49.7 bits (117), Expect = 6e-06
Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 11/116 (9%)
Query: 211 EELLSQSDVISINIPLNAATRHMIDKEAISKMKDGVVIVNTARGAVIDEPALISALKSGK 270
++LL Q+D + ++ LN H+I I +M+ G +VN A LK G+
Sbjct: 106 QDLLYQNDCVFLHCNLNEQNYHLIHDFTIKQMRQGAFLVNA---------ACAHTLKEGR 156
Query: 271 VRSAGLDVYENEP-QVPQELL-DLPNFIGVPHMGTHTVETIQKMEEFVVENVKSVI 324
+R A LDV E+EP + LL D N I P ++ + +M E V ++ I
Sbjct: 157 IRGAALDVNESEPFSFARGLLKDAWNLICTPLTACYSQQVSLEMSEAVATEIRQAI 212
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.135 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,911,125
Number of Sequences: 60738
Number of extensions: 798928
Number of successful extensions: 2017
Number of sequences better than 1.0e-05: 37
Number of HSP's better than 0.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1931
Number of HSP's gapped (non-prelim): 46
length of query: 349
length of database: 30,389,216
effective HSP length: 107
effective length of query: 242
effective length of database: 23,890,250
effective search space: 5781440500
effective search space used: 5781440500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)