ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0601 good TZ KOG1922 Cytoskeleton Rho GTPase effector BNI1 and related formins
r_klactIII0601 good TZ KOG1922 Signal transduction mechanisms Rho GTPase effector BNI1 and related formins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0601 202061 196536 -1842
(1842 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL271c [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 1266 0.0
YIL159w [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 293 2e-78
SPAC1F5.04c [TZ] KOG1922 Rho GTPase effector BNI1 and related fo... 252 4e-66
SPAC20G4.02c [TZ] KOG1922 Rho GTPase effector BNI1 and related f... 182 3e-45
SPCC895.05 [TZ] KOG1922 Rho GTPase effector BNI1 and related for... 152 5e-36
Hs6382071 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous 114 1e-24
Hs5803003 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous 114 1e-24
Hs4885183 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous 100 4e-20
7298710 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous 99 5e-20
Hs20535708 [TZ] KOG1923 Rac1 GTPase effector FRL 93 3e-18
Hs20550654 [TZ] KOG1923 Rac1 GTPase effector FRL 92 8e-18
Hs21071077 [TZ] KOG1922 Rho GTPase effector BNI1 and related for... 91 1e-17
CE23783 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 90 3e-17
7290137 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 89 7e-17
CE27278 [TZ] KOG1923 Rac1 GTPase effector FRL 87 3e-16
Hs5174401 [TZ] KOG1923 Rac1 GTPase effector FRL 86 6e-16
Hs13569895 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous 84 3e-15
Hs22060175 [TZ] KOG1922 Rho GTPase effector BNI1 and related for... 83 5e-15
Hs20533991 [TZ] KOG1922 Rho GTPase effector BNI1 and related for... 80 3e-14
At5g07780 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 80 4e-14
7294416 [TZ] KOG1923 Rac1 GTPase effector FRL 75 7e-13
At5g07770 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 67 2e-10
7295293 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 67 3e-10
7295751 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 60 2e-08
Hs13399326 [TZ] KOG1925 Rac1 GTPase effector FHOS 59 6e-08
At5g07760 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 59 6e-08
At3g25500 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 59 6e-08
Hs20561733 [TZ] KOG1925 Rac1 GTPase effector FHOS 58 2e-07
Hs7019375 [TZ] KOG1925 Rac1 GTPase effector FHOS 57 3e-07
Hs22056881 [TZ] KOG1922 Rho GTPase effector BNI1 and related for... 55 1e-06
At2g43800 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 54 2e-06
>YNL271c [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1953
Score = 1266 bits (3275), Expect = 0.0
Identities = 777/1917 (40%), Positives = 1086/1917 (56%), Gaps = 214/1917 (11%)
Query: 37 ATGGNHGS------SQPSQTRKELISSP--KRVFTTASLESATPIGGSKPLNKISSLNTH 88
AT N GS Q S E+ +SP F + S + ++PLNK S+LNT
Sbjct: 35 ATNSNTGSPTYASQQQHSPVGNEVSTSPASSSSFRKLNAPSRSTSTEARPLNKKSTLNTQ 94
Query: 89 NLSHYTMD------PEANSRSQSASLLTSPTKXXXXXXXXXXXXXXXXXXXXXXXXXXXX 142
NLS Y P ++ ++S S+ + +
Sbjct: 95 NLSQYMNGKLSGDVPVSSQHARSHSMQSKYSYSKRNSSQASNKLTRQHTGQSHSASSLLS 154
Query: 143 XXXXXILNRFLTNDGTLKLDRPENPEEINGLFMDLLIKRNVFDSVSSQDQKDMLNYPIEK 202
L++F T DG + L+ P +P E+ LF D++ KRN+F S+S Q+ ++ Y IEK
Sbjct: 155 QGSLTNLSKFTTPDGKIYLEMPSDPYEVEVLFEDIMYKRNIFQSLSEDKQEALMGYSIEK 214
Query: 203 KWLMVKQDLQSEFKRLKSTK----------------PRFSANDT---------------- 230
KWL+VKQDLQ+E K++++ P +AN +
Sbjct: 215 KWLIVKQDLQNELKKMRANTTSSSTASRTSMASDHHPILTANSSLSSPKSVLMTSASSPT 274
Query: 231 ----QNMLKRKT-------STSK--------------LNTQYEGMLHTNESQGSLLSP-S 264
N L T STSK LN Y G N S +L +
Sbjct: 275 STVYSNSLNHSTTLSSVGTSTSKGKKLVSGSLKKQPSLNNIYRGGAENNTSASTLPGDRT 334
Query: 265 HFPPEYYVRQIISKKIKNKELNDLWVSLRTEPLDWVISFLEAQGQVAIANLIITSMHQDT 324
+ PP +YV++I++ K+ + E+ DLWV+LRTE LDWV +F++ QG +A+AN+++ S+++ T
Sbjct: 335 NRPPIHYVQRILADKLTSDEMKDLWVTLRTEQLDWVDAFIDHQGHIAMANVLMNSIYK-T 393
Query: 325 TDNQNAVTDPQFLERETALFKCLRVLLNIRECLEEAVNSTLVTNALVEGLLSTKIPTRRL 384
+N + LE+E + FKC RVL + + L E L+T+ + EGL STK+ TR++
Sbjct: 394 APRENLTKE--LLEKENSFFKCFRVLSMLSQGLYEFSTHRLMTDTVAEGLFSTKLATRKM 451
Query: 385 ATETLIYLVTKDEDFKSRTAGLDCFSLVMESLNHETSLVQNIHMKAKFSTNDSTDPESNP 444
ATE + ++ K KSR F V+ SL+ + + QN+HM F S+
Sbjct: 452 ATEIFVCMLEKKN--KSR------FEAVLTSLDKKFRIGQNLHMIQNFKKMPQYF--SHL 501
Query: 445 QLYQVCKILQQWLYVVEQTLDGRGKMGSLVGASDEYRNNTGENSIYEYLVDSIVLIDQLC 504
L KI+Q WL+ VEQTLDGRGKMGSLVGASDE++N GEN+I EY ++V I+ LC
Sbjct: 502 TLESHLKIIQAWLFAVEQTLDGRGKMGSLVGASDEFKNGGGENAILEYCQWTMVFINHLC 561
Query: 505 LNNEDVKKRHMMRTQLKSFGLNRILQKMQLLDYPPLSTMLLQFEDAAIDDYNSLIDSQKF 564
++++ +R ++RT+L++ G+ RI+ K++LLDY + + +++ +DD+N +++
Sbjct: 562 SCSDNINQRMLLRTKLENCGILRIMNKIKLLDYDKVIDQIELYDNNKLDDFNVKLEANNK 621
Query: 565 TENVDMDDPVSILQKLTSSFKGTEAESYLLSMLQNLFLSSNKNAQESDDPGKNVQQLKLI 624
NVD+ DP+S+L+ L KGTE E L+S++Q+LFLSS+K +E+ + K +QLKL+
Sbjct: 622 AFNVDLHDPLSLLKNLWDICKGTENEKLLVSLVQHLFLSSSKLIEENQNSSKLTKQLKLM 681
Query: 625 DSLISNVAI-TTLDSESNFNVAIQRLYDSMQTDEIARRAILESRELTKKLEEVKAERDYL 683
DSL++NV++ +T D E+N N+AIQRLYD+MQTDE+ARRAILESR LTKKLEE++AERD L
Sbjct: 682 DSLVTNVSVASTSDEETNMNMAIQRLYDAMQTDEVARRAILESRALTKKLEEIQAERDSL 741
Query: 684 NDKISKAENGLVGQLQKELAERDLILDKTQRVTXXXXXXXXXXXXXXXXXXXXXXXXXXX 743
++K+SKAE+GLVGQL+ EL ERD IL K QRV
Sbjct: 742 SEKLSKAEHGLVGQLEDELHERDRILAKNQRVMQQLEAELEELKKKHLLEKHQQEVELRK 801
Query: 744 MLTIVNSKTSDDLESGSTVQNDPKPLNPERKTAIQNVLQRSLQKTEQDLLNESRRLGTAV 803
MLTI+NS+ + + LN K IQ VLQ L + ++D ++S++ G +
Sbjct: 802 MLTILNSRPEESFNKNEGTRGMNSSLNSSEKANIQKVLQDGLSRAKKDYKDDSKKFGMTL 861
Query: 804 GSKSRLKLLRSKMEDIENQARELEMTNFAD----------------VKPKQNQKFKEQVK 847
RLK+LR +ME+IEN+AR+LEMTNFA+ VK +N+ K VK
Sbjct: 862 QPNKRLKMLRMQMENIENEARQLEMTNFAEFEKDRLEPPIHIKKPKVKKMKNKDRKPLVK 921
Query: 848 GQQA--TKLAELRKKLAIIQNESNDITKFNIEARVNELFQXXXXXXXXXXXXXENKYNGF 905
Q+A KL +LR+ L IQ ESNDI+KFN+E RVNELF E KY GF
Sbjct: 922 PQEADVNKLNDLRRALTEIQMESNDISKFNVEERVNELFNEKKSLALKRLKELETKYKGF 981
Query: 906 HIDF-----ADDPELK--ELLTQSSNGGPSLDPTIVQRKVEEMNSIIDELNALKEEMKNR 958
IDF D P+ ++ T+ SLDP Q+K++E+N I D+L ++ + ++
Sbjct: 982 GIDFNVDEIMDSPKKNTGDVETEEDANYASLDPKTYQKKLDEINRITDQLLDIQTQTEHE 1041
Query: 959 ------PKTXXXXXXXXXXXXXXXXXXXXXXXXXXXHGSDIVSNGS---SFLESLSQKYS 1009
++ H +S+GS SFL++LSQKY
Sbjct: 1042 IQVEEDGESDLSSSSSDDESEEIYQDASPTQELRSEHSE--LSSGSGPGSFLDALSQKYG 1099
Query: 1010 TGQQTATS------TNGGRVGRETRYPGSGYHRKSFLNRLKNTTVNPTATSEHLPPFLTE 1063
TGQ S NG +G P K+F+NRL+ +TV+ P+L E
Sbjct: 1100 TGQNVTASAAFGENNNGSGIG-----PLHSKVEKTFMNRLRKSTVSSA-------PYLEE 1147
Query: 1064 LKSKVKMT--------XXXXXXXXXXXXSVSPGASLKSTEKPVSQFTEKPILTDAQQG-- 1113
L KV + S ++ EK + Q E + +QG
Sbjct: 1148 LTQKVNKVEPYEQNEDEGLDKKSLPENSTASAASAFDKAEKDMRQHVE-----NGKQGRV 1202
Query: 1114 ----SDKISNVILNDKYSPTTMQSEIGDSESIEAN----------PTTTIVSAASXXXXX 1159
DK ++ K + T ++ S+ ++ P + S
Sbjct: 1203 VNHEEDKTADFSAVSKLNNTDGAEDLSTQSSVLSSQPPPPPPPPPPVPAKLFGESLEKEK 1262
Query: 1160 XXXXXXXXXVSLGGTLTAVPSPLP---------------TALSPGIAXXXXXXXXXXXXX 1204
+ G + P P P T P +
Sbjct: 1263 KSEDDTVKQETTGDSPAPPPPPPPPPPPPMALFGKPKGETPPPPPLPSVLSSSTDGVIPP 1322
Query: 1205 XSANTPKATVTS----PLLPQSPSLFERYPRPKKKLKQLHWEKIDNAGDSIWKNAQAEKV 1260
P + + S PLLPQSPSLFE+YPRP KKLKQLHWEK+D +SIW +AEK
Sbjct: 1323 APPMMPASQIKSAVTSPLLPQSPSLFEKYPRPHKKLKQLHWEKLDCTDNSIWGTGKAEKF 1382
Query: 1261 ADDLFERGVLSQLEKAFAARETKSLKGKSKEANEKITFLSRDVSQQFGINLHMFSNLDVK 1320
ADDL+E+GVL+ LEKAFAARE KSL K KE +KITFLSRD+SQQFGINLHM+S+L V
Sbjct: 1383 ADDLYEKGVLADLEKAFAAREIKSLASKRKEDLQKITFLSRDISQQFGINLHMYSSLSVA 1442
Query: 1321 DVVGKVMKCDREFLSTPSVIEFLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEK 1380
D+V K++ CDR+FL TPSV+EFLSK IIEV+ NLAR + PYSTDWEGV +++DAKPPEK
Sbjct: 1443 DLVKKILNCDRDFLQTPSVVEFLSKSEIIEVSVNLARNYAPYSTDWEGVRNLEDAKPPEK 1502
Query: 1381 DPNELQRADQLYVEFMINLQPYWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQS 1440
DPN+LQRADQ+Y++ M+NL+ YWGSRMRA+T++T+YE++Y++L+ KLRK+D+AV +++S
Sbjct: 1503 DPNDLQRADQIYLQLMVNLESYWGSRMRALTVVTSYEREYNELLAKLRKVDKAVSALQES 1562
Query: 1441 ESLRHVFDVILAVGNYMNDSSKQAQGFKLSTLQRLTFIKDEKNSMTFLNYVEKIIRENYP 1500
++LR+VF+VILAVGN+MND+SKQAQGFKLSTLQRLTFIKD NSMTFLNYVEKI+R NYP
Sbjct: 1563 DNLRNVFNVILAVGNFMNDTSKQAQGFKLSTLQRLTFIKDTTNSMTFLNYVEKIVRLNYP 1622
Query: 1501 EYSHFVEELEPIFSVTKISIEQLVTDCKEFSQSVINVERSIEIGNLSDPSKFHPLDRVLN 1560
++ F+ ELEP+ V K+SIEQLV DCK+FSQS++NVERS+EIGNLSD SKFHPLD+VL
Sbjct: 1623 SFNDFLSELEPVLDVVKVSIEQLVNDCKDFSQSIVNVERSVEIGNLSDSSKFHPLDKVLI 1682
Query: 1561 KVVPVLPEARKKADLLSDEIKLSLLEFENLMKKFGEDANDKFSKNSFFQKFADFITEFKK 1620
K +PVLPEARKK DLL DE+KL+++EFE+LM +GED+ DKF+K SFF+KFADFI E+KK
Sbjct: 1683 KTLPVLPEARKKGDLLEDEVKLTIMEFESLMHTYGEDSGDKFAKISFFKKFADFINEYKK 1742
Query: 1621 AKTHNVKLXXXXXXXXXXKKMIEDQQRKQQEADSKATAKNLSTSQ-----EPSDDRDDIE 1675
A+ N+ KK++E+QQ++ QE + + N +S+ E D R ++
Sbjct: 1743 AQAQNLAAEEEERLYIKHKKIVEEQQKRAQEKEKQKENSNSPSSEGNEEDEAEDRRAVMD 1802
Query: 1676 KLLDKLKNAAPSKGDPSSTRKRALARKKL-------------LDGKSGASIFD----NIT 1718
KLL++LKNA P+K DPSS RKRAL RKK LD + G+ ++ + T
Sbjct: 1803 KLLEQLKNAGPAKSDPSSARKRALVRKKYLSEKDNAPQLLNDLDTEEGSILYSPEAMDPT 1862
Query: 1719 ADSTIEAFVEQNRTLTESPTAKKSASLPETESLSS--SKQDPADRARNLLLELRGPD 1773
AD+ I A E L S LP S+ +++ +DRAR LL ELRG D
Sbjct: 1863 ADTVIHA--ESPTPLATRGVMNTSEDLPSPSKTSALEDQEEISDRARMLLKELRGSD 1917
>YIL159w [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1375
Score = 293 bits (750), Expect = 2e-78
Identities = 163/541 (30%), Positives = 294/541 (54%), Gaps = 48/541 (8%)
Query: 1179 PSPLPTALSPGIAXXXXXXXXXXXXXXSANTPKATVTSPLLPQSPSLFERYPRP-KKKLK 1237
P P P L ++ + P ++S + +P+ + P P +K+LK
Sbjct: 820 PPPPPPPLPESLSMNKGPSNHDLVTPPAPPLPNGLLSSSSVSINPTTTDLKPPPTEKRLK 879
Query: 1238 QLHWEKIDNAGDSIWKNA-QAEKVADDLFERGVLSQLEKAFAARETKSL----------- 1285
Q+HW+K+++ D++W++ Q ++ +L G+ SQ+E F + +
Sbjct: 880 QIHWDKVEDIKDTLWEDTFQRQETIKELQTDGIFSQIEDIFKMKSPTKIANKRNAESSIA 939
Query: 1286 ----KGKSKEANEKITFLSRDVSQQFGINLHMFSNLDVKDVVGKVMKCDREFLSTPSVIE 1341
GKS +KI+FLSRD++QQFGINLHMFS L + V KV+ CD + + ++++
Sbjct: 940 LSSNNGKSSNELKKISFLSRDLAQQFGINLHMFSQLSDMEFVMKVLNCDNDIVQNVNILK 999
Query: 1342 FLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNELQRADQLYVEFMINLQP 1401
F K ++ + ++ + PYS +G K ++LQRAD++++E INL+
Sbjct: 1000 FFCKEELVNIPKSMLNKYEPYSQGKDG-----------KAVSDLQRADRIFLELCINLRF 1048
Query: 1402 YWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMNDSS 1461
YW +R +++ ++TYE+DY DL+ KL+KID A+ + +S + + +I +GN+MN
Sbjct: 1049 YWNARSKSLLTLSTYERDYYDLIFKLQKIDDAISHLNRSPKFKSLMFIITEIGNHMN--K 1106
Query: 1462 KQAQGFKLSTLQRLTFIKDE-KNSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKISI 1520
+ +G KL +L +L F++ +++FL+++EK+IR YP+ FV++L+ I + KIS+
Sbjct: 1107 RIVKGIKLKSLTKLAFVRSSIDQNVSFLHFIEKVIRIKYPDIYGFVDDLKNIEDLGKISL 1166
Query: 1521 EQLVTDCKEFSQSVINVERSIEIGNLSDPSKFHPLDRVLNKVVPVLPEARKKADLLSDEI 1580
E + ++C EF + + ++ ++G LS P D+++ KV + A+ K++LL +
Sbjct: 1167 EHVESECHEFHKKIEDLVTQFQVGKLSKEENLDPRDQIIKKVKFKINRAKTKSELLIGQC 1226
Query: 1581 KLSLLEFENLMKKFGEDANDKFSKNSFFQKFADFITEFKKAKTHNVKLXXXXXXXXXXKK 1640
KL+L++ LMK +GED DK SKN FFQ F +F+ FKK N++ ++
Sbjct: 1227 KLTLIDLNKLMKYYGEDPKDKESKNEFFQPFIEFLAMFKKCAKENIE----------KEE 1276
Query: 1641 MIEDQQRKQQEADSKATAKNLSTSQEPSD----DRDDIEKLLDKLKNAAPSKGDPSSTRK 1696
M ++++ D + ++ S + +D +RD ++ L+ KL+ K DP R+
Sbjct: 1277 MERVYEQRKSLLDMRTSSNKKSNGSDENDGEKVNRDAVDLLISKLREV---KKDPEPLRR 1333
Query: 1697 R 1697
R
Sbjct: 1334 R 1334
>SPAC1F5.04c [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1841
Score = 252 bits (643), Expect = 4e-66
Identities = 155/526 (29%), Positives = 267/526 (50%), Gaps = 43/526 (8%)
Query: 1231 RPKKKLKQLHWEKIDNAGD-SIWKNA--QAEKVADDLFERGVLSQLEKAFAARETKSLKG 1287
RP ++LKQ+HWEK+++ + + W +A K+ + L GVL +L+++FA +E K+L
Sbjct: 985 RPTRRLKQMHWEKLNSGLEFTFWTGPSDEANKILETLHTSGVLDELDESFAMKEAKTLV- 1043
Query: 1288 KSKEANEKITFLSRDVSQQFGINLHMFSNLDVKDVVGKVMKCDREFLSTPSVIEFLSKPT 1347
K+ + ++S ++ + FGI+ H S+ + +++ ++ CD S +EFLS
Sbjct: 1044 --KKTCARTDYMSSELQKLFGIHFHKLSHKNPNEIIRMILHCDD---SMNECVEFLSSDK 1098
Query: 1348 IIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNELQRADQLYVEFMINLQPYWGSRM 1407
++ L PY DW + D EKD +EL R D LYV +++L YW RM
Sbjct: 1099 VLNQPK-LKADLEPYRIDW---ANGGDLVNSEKDASELSRWDYLYVRLIVDLGGYWNQRM 1154
Query: 1408 RAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMNDSSKQAQGF 1467
A+ + E +Y +LV + + I RA + S+ + + +IL +GNYMND +QA+GF
Sbjct: 1155 NALKVKNIIETNYENLVRQTKLIGRAALELRDSKVFKGLLYLILYLGNYMNDYVRQAKGF 1214
Query: 1468 KLSTLQRLTFIKDEKNSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKISIEQLVTDC 1527
+ +LQRL IK+ N+ + L+ ++ IR+++P++ +F EL + K++IE + +C
Sbjct: 1215 AIGSLQRLPLIKNANNTKSLLHILDITIRKHFPQFDNFSPELSTVTEAAKLNIEAIEQEC 1274
Query: 1528 KEFSQSVINVERSIEIGNLSDPSKFHPLDRVLNKVVPVLPEARKKADLLSDEIKLSLLEF 1587
E + N++ + G LSDP+ FHP D++L+ ++P L E KK D L + ++
Sbjct: 1275 SELIRGCQNLQIDCDSGALSDPTVFHPDDKILSVILPWLMEGTKKMDFLKEHLRTMNTTL 1334
Query: 1588 ENLMKKFGEDANDKFSKNSFFQKFADFITEFKKAKTHNVKLXXXXXXXXXXKKMIEDQQR 1647
N M+ FGE ND SKN FF++ FI ++ KA++ N+K ++ +R
Sbjct: 1335 NNAMRYFGEQPNDPNSKNLFFKRVDSFIIDYSKARSDNLK---------SEEEEASQHRR 1385
Query: 1648 KQQEADSKATAKNLSTSQEPSDDRDDIEKLLDKLKNAAPSKGDPSSTRKRALARKKLLDG 1707
+ K + S+ D + ++ LDKL+N + + R + G
Sbjct: 1386 LNLVNNHKEHVLERAMSENNKMDNEAMDGFLDKLRNV------KLESHHKPRNRSAITMG 1439
Query: 1708 KSGASIFDNITADSTIEAFVEQNRTLTESPTAKKSASLPETESLSS 1753
K E +E T T+S AK +P+ S+ S
Sbjct: 1440 K---------------EHLIEAPNTSTKSSPAKNELFVPKRSSVKS 1470
Score = 79.0 bits (193), Expect = 7e-14
Identities = 103/464 (22%), Positives = 205/464 (43%), Gaps = 71/464 (15%)
Query: 261 LSPSHFPPEYYVRQIISKKIKNKELNDLWVSLRTEPLDWVISFLEAQGQVAIANLIITSM 320
L+ H P ++V Q+ +K I N +L L L T+ W+ FLE QG A+ NL+
Sbjct: 292 LAAVHRPVSWFVIQLWNKTISNLQLITLSSLLSTQSDRWISLFLELQGLRALHNLL---- 347
Query: 321 HQDTTDNQNAVTDPQFLERETALFKCLRVLLNIRECLEEAVNSTLVTNALVEGLLSTKIP 380
T N +AV PQ E + +C+ LL + L +++ + A+ L+S +
Sbjct: 348 ---TYFNSSAVVQPQQAE----VPRCMLTLLKKKPTL--VTSNSYIFQAITVTLISPNLL 398
Query: 381 TRRLATETLIYLVTKDEDFKSRTAGLDCFSLVMESLNHETSLVQNIHMKAKFSTNDSTDP 440
R++A + L ++++ E LV +I ++ F ++
Sbjct: 399 PRKVAADLLTWVLSLKEP-----------------------LVVSI-LETGFKEINAEYE 434
Query: 441 ESNPQLYQVCKILQQWLYVVEQTLDGRGKMGSLVGASDEYRNNTGEN----SIYEYLVDS 496
+ P + K + ++E+ L + S RN+ + + EY +
Sbjct: 435 KEVPLFFGWIKSFKD--IILEKEL-------ARTPPSSPARNSASSSPSNIAFLEYCTST 485
Query: 497 IVLIDQLCLNNEDVKKRHMMRT--QLKSFGLNRILQKMQLLDYPPLSTMLLQFEDAAIDD 554
+ I+QL + E++++ + L+ G++ ++Q ++ L L +E ++
Sbjct: 486 MEFINQLIVACEELEQGFDLDILDSLRESGIHEVIQLLRNFPDQQLEKQLNIYESE--EE 543
Query: 555 YNSLIDSQKFTENVD--MDDPVSILQKLTSSFKGTEAESYLLSMLQNLFLSSNKNAQESD 612
++ SQ E+VD M + SIL + F E L S +QN+ L+ Q+
Sbjct: 544 RRTI--SQTTHEDVDSFMSNESSILSSF-NEFASNEVGRLLESTIQNILLAKGTEKQK-- 598
Query: 613 DPGKNVQQLKLIDSLISNVAITTLDSESNFNVAIQR----LYDSMQTDEIARRAILESRE 668
V+ +K+ +SL+ + + + S +F ++Q L + +D+ AR A+ E++
Sbjct: 599 -----VKLIKVFNSLLQRILLNSKVSNESFEDSLQASLNMLTERFYSDDTARNALKEAKA 653
Query: 669 LTKKLEEVKAERDYLNDKISKAENGLVGQLQKELA-ERDLILDK 711
E++ ERD + +++ L+ +L KE+ ++D+IL +
Sbjct: 654 SRAMAEKMVIERDAMAAQVNLGAEDLIAKLNKEVEDQKDVILSQ 697
>SPAC20G4.02c [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1372
Score = 182 bits (463), Expect = 3e-45
Identities = 119/459 (25%), Positives = 226/459 (48%), Gaps = 21/459 (4%)
Query: 1232 PKKKLKQLHWEKIDNAGD-SIWKNAQAEK--VADDLFERGVLSQLEKAFAARETKSLKGK 1288
P K+LKQLHW++++ + ++W A+ + L G+ QLE + RE
Sbjct: 874 PSKRLKQLHWKRLEVPFEKTLWNIVVADPYLLTLKLTAEGIFKQLEDCYPLREVTV---S 930
Query: 1289 SKEANEKITFLSRDVSQQFGINLHMFSNLDVKDVVGKVMKCDREFLSTPSVIEFLSKPTI 1348
+K+ E F+ D+ Q I LH F++L ++ K CD + + +++F +
Sbjct: 931 NKKVKEYTGFMPVDLQQMVSIRLHRFNSLTPIEIAKKFFHCDHDIME---LVDFFNDRKF 987
Query: 1349 IEVTNNLARYFNPY-STDWEGVTSVDDAKPPEKDPNELQRADQLYVEFMINLQPYWGSRM 1407
L + PY S+ E V V + EL R DQ+Y ++++ Y+ RM
Sbjct: 988 FR-QEGLKKQLKPYMSSRNEEVMEVSEKLL------ELSRFDQIYTLIVVDIDTYYEKRM 1040
Query: 1408 RAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMNDSSKQAQGF 1467
A+ + + ++ D ++RK+ A ++ S ++ +++L +GN+MND+ ++A+G+
Sbjct: 1041 AALKIKSFLANNFRDFRRQIRKLHCASLELKSSLHFKYFLNLVLHIGNFMNDAPRRAKGY 1100
Query: 1468 KLSTLQRLTFIKDEKNSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKISIEQLVTDC 1527
+L +L R + IK++K +T L+ +EKI+R ++P+ F+ +L+ I +++ ++EQL DC
Sbjct: 1101 RLESLLRASMIKNDKTGLTLLHTIEKIVRTHFPQLEAFLVDLKAIPEISRFNLEQLEQDC 1160
Query: 1528 KEFSQSVINVERSI-EIGNLSDPSKFHPLDRVLNKVVPVLPEARKKADLLSDEIKLSLLE 1586
+ + + NVE+ G S+ HP D + +VP +P + D L+ +I
Sbjct: 1161 NDICERMKNVEKDFSNEGIFSNHKALHPDDHICEVMVPWIPSGKSMVDELNSDITELKTT 1220
Query: 1587 FENLMKKFGEDANDKFSKNSFFQKFADFITEFKKAKTHNVKLXXXXXXXXXXKKMIEDQQ 1646
+ + +GE+ ++ S FF + I E+KKA T N K+ + ++
Sbjct: 1221 LKTTLLMYGENPDEPTSSARFFNNLNEIILEYKKASTVNQKMEKEEELAFLRLQALK-AS 1279
Query: 1647 RKQQEADSKATAKNLSTSQEPSDDRDDIEKLL--DKLKN 1683
K A++ ++KN S + ++K L D L N
Sbjct: 1280 VKSNNAENSGSSKNEEVSATMENLISQLQKGLCDDSLSN 1318
Score = 53.1 bits (126), Expect = 4e-06
Identities = 59/231 (25%), Positives = 103/231 (44%), Gaps = 44/231 (19%)
Query: 164 PENPEEINGLFMDLLIKRNVFDSVSSQDQKDMLNYPI--EKKWLMVKQDLQSEFKRLKST 221
P++P +N LF D+L + S S + N + E KW + L K LK
Sbjct: 106 PDDPNLVNELFDDVLKRLREEKSDSGEQFHWDANVTLSQENKWSFITGYLSRNDKFLK-- 163
Query: 222 KPRFSANDTQNMLKRKTSTSKLNTQYEGMLHTNESQGSLLSPSHFPPEYYVRQIISKKIK 281
S+ND S+LN + S++S Y+ ++ +K
Sbjct: 164 ---ISSND-----------SELNVK-----------ASVIS--------YIEKLSCTPLK 190
Query: 282 NKELNDLWVSLRTEPLDWVISFLEAQGQVAIANLIITSMHQDTTDNQNAVTDPQFLERET 341
K + L V+LRTE + WV FL G + +A I+ ++H+ + + P + E
Sbjct: 191 LKYVESLAVALRTESVTWVRYFLLMGGHIVLAK-ILQAIHE-----KKHLKSPD-ITLEI 243
Query: 342 ALFKCLRVLLNIRECLEEAVNSTLVTNALVEGLLSTKIPTRRLATETLIYL 392
A+ K +R ++ + + +++ +++V LLSTK+ R+LA E L +L
Sbjct: 244 AILKSMRCIIGQKIGTDFYLSNKYPIDSVVHCLLSTKLLVRKLAAELLTFL 294
>SPCC895.05 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1461
Score = 152 bits (384), Expect = 5e-36
Identities = 140/579 (24%), Positives = 270/579 (46%), Gaps = 37/579 (6%)
Query: 1223 PSLFERYPRPKKKLKQLHWEKIDNA-GDSIWKN--AQAEKVADDLFERGVLSQLEKAFAA 1279
PSL + + +P + LK++HW+++D G +++ + A + G+L L++ F
Sbjct: 843 PSLRDLH-KPTRPLKRVHWQRVDPLPGPNVFTKFCLNFDITAKVFIDNGLLDFLDEKFDN 901
Query: 1280 RETKSLKGKSKEANEKITFLSRDVSQQFGINLHMFSNLDVKDVVGKVMKCDREFLSTPSV 1339
+ + ++++ + L V Q I L SN+ V+D+V K + + +FL P+
Sbjct: 902 TPREDFVAV-EISDQRSSLLPDTVEQNMAIILRSVSNMPVEDLVQKFL-VEPDFL--PAS 957
Query: 1340 IEFLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNELQRADQLYVEFMINL 1399
I + + ++ TN F PYSTD+ + + K P D N L ++ +V F++NL
Sbjct: 958 ILYFDRASLAS-TNAYTDPFIPYSTDY----TKKNPKEPTADVNSLSYFEKFFVLFVVNL 1012
Query: 1400 QPYWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMND 1459
+ Y+ RM+A+ +T D L +++++ I + ++ F V+L +GNY N+
Sbjct: 1013 RHYFQERMKALKFRSTLFGDLEILEVRMKEVIDTSDSIMEDKNFAEFFQVLLIIGNYFNE 1072
Query: 1460 SSKQAQGFKLSTLQRLTFIKDEKNSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKIS 1519
+A F L + RL ++D +++T ++Y ++IIR +PE + I SV+ +
Sbjct: 1073 PYDRASAFSLYMIYRLETLRDSSSALTLMHYFDEIIRTRFPELLQAESTFKKIQSVSGYN 1132
Query: 1520 IEQLVTDCKEFSQSVINVERSIEIGNLSDPSKFHPLDRVLNKVVPVLPEARKKADLLSDE 1579
I+ +V + + S++ G LS + HP D+ + + LPEA+++ +
Sbjct: 1133 IDAMVAGVDGAYDEFCDFQTSLKDGALSKCDQHHPDDKAYDILSEWLPEAKERIRNIKKL 1192
Query: 1580 IKLSLLEFENLMKKFGE-DANDKFSKNSFFQKFADFITEFKKAKTHNVKLXXXXXXXXXX 1638
L + EN +K E D+ DK +NSFF+ F + AK N +
Sbjct: 1193 KTDMLTKLENTVKYLCEYDSIDKV-RNSFFKNLNSFYEMYSIAKAENEE----RFEKEKR 1247
Query: 1639 KKMIEDQQ---RKQQEADSKATAKNLSTSQEPSDDRDD--------IEKLLDKLKNAAPS 1687
+ M ED+ R +Q+ A +N E SDD+ D +E + +K+++A+
Sbjct: 1248 RIMSEDRDKLIRGRQKTSIVAKYRNKRELPEDSDDKQDTASKDKNSLETIDEKMEDASKI 1307
Query: 1688 KGDPSS---TRKRALARKKLLDGKSGASIFD-NITADSTIEAFVEQNRTLTESPTAKKSA 1743
+GD + L + + L+ A D IT S + + ++ T + + +
Sbjct: 1308 EGDAKTGDDNEMEDLDKMEDLEKPDYAEEKDPYITVMSELRSRIQNVPKRTVTVYSDEGV 1367
Query: 1744 SLPETESLSSSKQDPADRARNLLLELRGPDERKDASPSP 1782
+ E + D D+A+ +L ++ G + +S +P
Sbjct: 1368 ATLEP---GAQGDDVVDKAKMILEKMEGHSQLLTSSANP 1403
>Hs6382071 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous
Length = 1096
Score = 114 bits (286), Expect = 1e-24
Identities = 107/466 (22%), Positives = 210/466 (44%), Gaps = 42/466 (9%)
Query: 1231 RPKKKLKQLHWEKIDN---AGDSIWKNAQAEKVAD-DLFERGVLS-----QLEKAFAARE 1281
+P+ +K+++W KI+ + + W + +K + DLF + L+ +++K A E
Sbjct: 633 KPEVSMKRINWSKIEPTELSENCFWLRVKEDKFENPDLFAKLALNFATQIKVQKNAEALE 692
Query: 1282 TKSLKGKSKEANEKITFLSRDVSQQFGINLHMFSNLDVKDVVGKVMKCDREFLSTPSVIE 1341
K G +K+ +++ L +Q I L + + +D+ +++ + + LS +
Sbjct: 693 EKKT-GPTKKKVKELRILDPKTAQNLSIFLGSY-RMPYEDIRNVILEVNEDMLSEALIQN 750
Query: 1342 FLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNELQRADQLYVEFMINLQP 1401
+ ++ N LA N Y DD PE+ + L QP
Sbjct: 751 LVKHLPEQKILNELAELKNEY----------DDLCEPEQFGVVMSSVKML--------QP 792
Query: 1402 YWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMNDSS 1461
R+ +I T+E+ +++ + + A + +++SES + +++L VGNYMN S
Sbjct: 793 ----RLSSILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGS 848
Query: 1462 KQAQ--GFKLSTLQRLTFIKDEKNSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKIS 1519
+ AQ GFK++ L ++ K T L+++ I E Y + F EELE + S +K+S
Sbjct: 849 RNAQSLGFKINFLCKIRDTKSADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVS 908
Query: 1520 IEQLVTDCKEFSQSVINVERSIEIGNLSDPSKFHPLDRVLNKVVPVLPEARKKADLLSDE 1579
+ L ++ Q ++++ER I+ P + D+ + K+ AR++ + LS
Sbjct: 909 AQILKSNLASMEQQIVHLERDIK----KFPQAENQHDKFVEKMTSFTKTAREQYEKLSTM 964
Query: 1580 IKLSLLEFENLMKKFGEDANDKFSKNSFFQKFADFITEFKKAKTHNVKLXXXXXXXXXXK 1639
+ +ENL + F D+ S FF +F T F +A N K K
Sbjct: 965 HNNMMKLYENLGEYFIFDSK-TVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAK 1023
Query: 1640 KMIEDQQRKQQEADSKATAKNLSTSQEPSDDRDDIEKLLDKLKNAA 1685
+ ++ +Q++ + + K L + D+ ++ LL+ L++ A
Sbjct: 1024 --LAKEKAEQEKLERQKKKKQLIDINKEGDETGVMDNLLEALQSGA 1067
>Hs5803003 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous
Length = 1101
Score = 114 bits (286), Expect = 1e-24
Identities = 107/466 (22%), Positives = 210/466 (44%), Gaps = 42/466 (9%)
Query: 1231 RPKKKLKQLHWEKIDN---AGDSIWKNAQAEKVAD-DLFERGVLS-----QLEKAFAARE 1281
+P+ +K+++W KI+ + + W + +K + DLF + L+ +++K A E
Sbjct: 633 KPEVSMKRINWSKIEPTELSENCFWLRVKEDKFENPDLFAKLALNFATQIKVQKNAEALE 692
Query: 1282 TKSLKGKSKEANEKITFLSRDVSQQFGINLHMFSNLDVKDVVGKVMKCDREFLSTPSVIE 1341
K G +K+ +++ L +Q I L + + +D+ +++ + + LS +
Sbjct: 693 EKKT-GPTKKKVKELRILDPKTAQNLSIFLGSY-RMPYEDIRNVILEVNEDMLSEALIQN 750
Query: 1342 FLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNELQRADQLYVEFMINLQP 1401
+ ++ N LA N Y DD PE+ + L QP
Sbjct: 751 LVKHLPEQKILNELAELKNEY----------DDLCEPEQFGVVMSSVKML--------QP 792
Query: 1402 YWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMNDSS 1461
R+ +I T+E+ +++ + + A + +++SES + +++L VGNYMN S
Sbjct: 793 ----RLSSILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGS 848
Query: 1462 KQAQ--GFKLSTLQRLTFIKDEKNSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKIS 1519
+ AQ GFK++ L ++ K T L+++ I E Y + F EELE + S +K+S
Sbjct: 849 RNAQSLGFKINFLCKIRDTKSADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVS 908
Query: 1520 IEQLVTDCKEFSQSVINVERSIEIGNLSDPSKFHPLDRVLNKVVPVLPEARKKADLLSDE 1579
+ L ++ Q ++++ER I+ P + D+ + K+ AR++ + LS
Sbjct: 909 AQILKSNLASMEQQIVHLERDIK----KFPQAENQHDKFVEKMTSFTKTAREQYEKLSTM 964
Query: 1580 IKLSLLEFENLMKKFGEDANDKFSKNSFFQKFADFITEFKKAKTHNVKLXXXXXXXXXXK 1639
+ +ENL + F D+ S FF +F T F +A N K K
Sbjct: 965 HNNMMKLYENLGEYFIFDSK-TVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAK 1023
Query: 1640 KMIEDQQRKQQEADSKATAKNLSTSQEPSDDRDDIEKLLDKLKNAA 1685
+ ++ +Q++ + + K L + D+ ++ LL+ L++ A
Sbjct: 1024 --LAKEKAEQEKLERQKKKKQLIDINKEGDETGVMDNLLEALQSGA 1067
>Hs4885183 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous
Length = 1248
Score = 99.8 bits (247), Expect = 4e-20
Identities = 118/521 (22%), Positives = 229/521 (43%), Gaps = 81/521 (15%)
Query: 1216 SPLLPQSPSLFERYPRPKKKLKQLHWEKI---DNAGDSIWKNAQAEKVADDLFERGVL-S 1271
+P+LP + + Y +P+ +L++ +W K+ D + D W KV +D FE L +
Sbjct: 739 APVLPFGLTPKKLY-KPEVQLRRPNWSKLVAEDLSQDCFWT-----KVKEDRFENNELFA 792
Query: 1272 QLEKAFAARETKSLK----GKSKEANEK-----ITFLSRDVSQQFGINLHMFSN--LDVK 1320
+L F+A +TK+ K G+ K++ +K + L +Q I L F ++K
Sbjct: 793 KLTLTFSA-QTKTKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIK 851
Query: 1321 DVVGKVMKCDREFLSTPSVIEFLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEK 1380
+V+ +V E + T S+I+ L K P + ++ + D
Sbjct: 852 NVILEV----NEAVLTESMIQNLIKQM-------------PEPEQLKMLSELKD------ 888
Query: 1381 DPNELQRADQLYVEFMINLQPYWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQS 1440
+ ++L ++Q V ++ P R+ AI + + ++ ++ + A + + +S
Sbjct: 889 EYDDLAESEQFGV--VMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKS 946
Query: 1441 ESLRHVFDVILAVGNYMNDSSKQAQ--GFKLSTLQRLTFIKDEKNSMTFLNYVEKIIREN 1498
ES ++ ++ L VGNYMN S+ A GF +S L +L K MT L+++ ++ +
Sbjct: 947 ESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCEND 1006
Query: 1499 YPEYSHFVEELEPIFSVTKISIEQLVTDCKEFSQSVINVERSIEIGNLSDPSKFHPLDRV 1558
YP+ F +EL + +++S E L + + + + +VER ++ + P+ D+
Sbjct: 1007 YPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQ----NFPAATDEKDKF 1062
Query: 1559 LNKVVPVLPEARKKADLLSDEIKLSLLEFENLMKKFGE---DANDKFSKNSFFQKFADFI 1615
+ K+ + +A+++ +++++ E L K+ GE K S FF +F
Sbjct: 1063 VEKMTSFVKDAQEQ----YNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHNFR 1118
Query: 1616 TEF--------KKAKTHNVKLXXXXXXXXXXKKMIEDQQRKQQEADSKATAKNLSTSQEP 1667
F K+ KT K+ +E QQ+++Q D A
Sbjct: 1119 NMFLQAVKENQKRRKTEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNA----------E 1168
Query: 1668 SDDRDDIEKLLDKLKNAAP---SKGDPSSTRKRALARKKLL 1705
D+ ++ LL+ L++ A +G + RK A LL
Sbjct: 1169 GDETGVMDSLLEALQSGAAFRRKRGPRQANRKAGCAVTSLL 1209
Score = 68.9 bits (167), Expect = 7e-11
Identities = 57/227 (25%), Positives = 108/227 (47%), Gaps = 13/227 (5%)
Query: 494 VDSIVLIDQLCLNNEDVKKRHMMRTQLKSFGLNRILQKMQLLDYPPLSTMLLQFEDAAID 553
V + LI+ L E++ R +R++L GL+++LQ ++ ++ + L F++ +
Sbjct: 303 VGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQDLREIENEDMRVQLNVFDEQGEE 362
Query: 554 DYNSLIDSQKFTENVDMDDPVSILQKLTSSFKGTEAESYLLSMLQNLFLSSNKNAQESDD 613
D L + ++MDD + Q L ++ K ++AE + LS+LQ+L L N D
Sbjct: 363 DSYDL-KGRLDDIRMEMDDFNEVFQILLNTVKDSKAEPHFLSILQHLLLVRN-------D 414
Query: 614 PGKNVQQLKLIDSLISNVAITTLDSESNFN-----VAIQRLYDSMQTDEIARRAILESRE 668
Q KLI+ IS + + ++ +F + I+ L D M ++ ++ E
Sbjct: 415 YEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEKSEAKAAE 474
Query: 669 LTKKLEEVKAERDYLNDKISKAENGLVGQLQKELAERDLILDKTQRV 715
L KKL+ R L ++ K E+ +LQ E+D + + Q++
Sbjct: 475 LEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQI 521
>7298710 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous
Length = 1091
Score = 99.4 bits (246), Expect = 5e-20
Identities = 113/535 (21%), Positives = 223/535 (41%), Gaps = 90/535 (16%)
Query: 1179 PSPLPTALSPGIAXXXXXXXXXXXXXXSANTPKATVTSPLLPQSPSLFERYPRPKKK--- 1235
P P+P + PG P + P++P P +PKKK
Sbjct: 568 PPPMPGMMRPG----------------GGPPPPPMMMGPMVPVLPHGL----KPKKKWDV 607
Query: 1236 ---LKQLHWEKIDNAGDS---IWKNAQAEKVADDLFERGVLSQLEKAFAARETKSLKGKS 1289
+K+ +W+ I A S W Q +K+A D F L++L F++ K +K +
Sbjct: 608 KNPMKRANWKAIVPAKMSDKAFWVKCQEDKLAQDDF----LAELAVKFSS---KPVKKEQ 660
Query: 1290 KEANEKITFLSRD----------VSQQFGINLH-MFSNLDVKDVVGKVMKCDREFLST-- 1336
K+A +K T L++ +Q I L +L + + +++CD + LS+
Sbjct: 661 KDAVDKPTTLTKKNVDLRVLDSKTAQNLAIMLGGSLKHLSYEQIKICLLRCDTDILSSNI 720
Query: 1337 -PSVIEFLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNELQRADQLYVEF 1395
+I++L P ++ + P + ++ + K
Sbjct: 721 LQQLIQYLPPPEHLKRLQEIKAKGEPLPPIEQFAATIGEIK------------------- 761
Query: 1396 MINLQPYWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGN 1455
L P R+ + TY D+ + A + I S+ + ++IL +GN
Sbjct: 762 --RLSP----RLHNLNFKLTYADMVQDIKPDIVAGTAACEEIRNSKKFSKILELILLLGN 815
Query: 1456 YMNDSSKQ--AQGFKLSTLQRLTFIKDEKNSMTFLNYVEKIIRENYPEYSHFVEELEPIF 1513
YMN SK A GF++S L +L+ KD N T L+Y+ ++ + +P+ +F ++L +
Sbjct: 816 YMNSGSKNEAAFGFEISYLTKLSNTKDADNKQTLLHYLADLVEKKFPDALNFYDDLSHVN 875
Query: 1514 SVTKISIEQLVTDCKEFSQSVINVERSIEIGNL--SDPSKFHPLDRVLNKVVPVLPEARK 1571
++++++ + ++ + +V N+E ++ + D KF V+ K E R+
Sbjct: 876 KASRVNMDAIQKAMRQMNSAVKNLETDLQNNKVPQCDDDKF---SEVMGKFA---EECRQ 929
Query: 1572 KADLLSD-EIKLSLLEFENLMKKFGEDANDKFSKNSFFQKFADFITEFKKAKTHNVKLXX 1630
+ D+L ++++ L +++L + + D + K++ FF F F+ A NV++
Sbjct: 930 QVDVLGKMQLQMEKL-YKDLSEYYAFDPS-KYTMEEFFADIKTFKDAFQAAHNDNVRVRE 987
Query: 1631 XXXXXXXXKKMIEDQQRKQQEADSKATAKNLSTSQEPSDDRDDIEKLLDKLKNAA 1685
++ E R+QQE + K + P ++ LL+ L+ +
Sbjct: 988 ELEKKRRLQEAREQSAREQQERQQR--KKAVVDMDAPQTQEGVMDSLLEALQTGS 1040
>Hs20535708 [TZ] KOG1923 Rac1 GTPase effector FRL
Length = 853
Score = 93.2 bits (230), Expect = 3e-18
Identities = 81/324 (25%), Positives = 145/324 (44%), Gaps = 30/324 (9%)
Query: 1406 RMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMNDSSKQA- 1464
+M + I + + L +L I A I+ S+ L+ + ++ILA+GNYMN S + A
Sbjct: 542 KMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAV 601
Query: 1465 QGFKLSTLQRLTFIKDEKNSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKISIEQLV 1524
GFKL +L L K T L+Y+ +++E Y + S F EL + +S+E ++
Sbjct: 602 YGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENVL 661
Query: 1525 TDCKEFSQSVINVERSIEIGNLSDPSKFHPLDRVLNKVVPVLPEARKKADLLSDEIKLSL 1584
D KE + + +R + + + K + +LN K L D+ K++
Sbjct: 662 LDVKELQRGMDLTKREYTMHDHNTLLK----EFILNN--------EGKLKKLQDDAKIAQ 709
Query: 1585 LEFENLMKKFGEDANDKFSKNS-FFQKFADFITEFKKAKTHN---VKLXXXXXXXXXXKK 1640
F++++K FGE N K + S FF F F+ +K+A+ N K ++
Sbjct: 710 DAFDDVVKYFGE--NPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQE 767
Query: 1641 MIEDQQ----------RKQQEADSKATAKNLSTSQEPSDDRDD-IEKLLDKLKNAAPSKG 1689
+ +QQ R+QQE ++ + + ++ + +D IE ++ L+N +
Sbjct: 768 ALMEQQDPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRA 827
Query: 1690 DPSSTRKRALARKKLLDGKSGASI 1713
D R + L +GA I
Sbjct: 828 DAVRRSVRRRFDDQNLRSVNGAEI 851
>Hs20550654 [TZ] KOG1923 Rac1 GTPase effector FRL
Length = 347
Score = 92.0 bits (227), Expect = 8e-18
Identities = 78/314 (24%), Positives = 138/314 (43%), Gaps = 42/314 (13%)
Query: 1406 RMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMNDSSKQA- 1464
RM + + ++ + L +L I A ++ S+ L+ + ++ILA+GNYMN S + A
Sbjct: 45 RMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAV 104
Query: 1465 QGFKLSTLQRLTFIKDEKNSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKISIEQLV 1524
GFKL +L L K MT L+++ ++E YP+ ++F EL + +S+E ++
Sbjct: 105 YGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVL 164
Query: 1525 TDCKEFSQSVINVERSIEIGNLSDPSKFHPLDRVLNKVVPVLPEARKKADLLSDEIKLSL 1584
D KE + + + R I + S F L K D L + K +
Sbjct: 165 LDVKELGRGMELIRRECSIHDNSVLRNF-------------LSTNEGKLDKLQRDAKTAE 211
Query: 1585 LEFENLMKKFGEDANDKFSKNSFFQKFADFITEFKKAKTHNVKLXXXXXXXXXXKKMIED 1644
+ +++ FGE + FF F FI +K+A+ N +K E+
Sbjct: 212 EAYNAVVRYFGESPKTT-PPSVFFPVFVRFIRSYKEAEQEN-----------EARKKQEE 259
Query: 1645 QQRKQQEADSKATAKNLSTSQEPSDDRDDIEKLLDKLKNAAPSKGDPSSTRKRALARKKL 1704
R++Q A AK L ++ ++L+ +L+ R++A + +
Sbjct: 260 VMREKQLAQE---AKKLDAKTPSQRNKWQQQELIAELR------------RRQAKEHRPV 304
Query: 1705 LDGKSGASIFDNIT 1718
+GK G +I D IT
Sbjct: 305 YEGKDG-TIEDIIT 317
>Hs21071077 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1078
Score = 91.3 bits (225), Expect = 1e-17
Identities = 106/508 (20%), Positives = 216/508 (41%), Gaps = 68/508 (13%)
Query: 1230 PRPKKKLKQLHWEKI--DNAGDSIWKNAQAEKVADDLFERGVLSQLEKAFAARETK---- 1283
P+P LK +W K+ + ++W KV F+ L LE+ F+A + +
Sbjct: 604 PQPTNALKSFNWSKLPENKLEGTVWTEIDDTKV----FKILDLEDLERTFSAYQRQQDFF 659
Query: 1284 -SLKGKSKEAN------------EKITFLSRDVSQQFGINLHMFSNLDVKDVVGKVMKCD 1330
+ K KEA+ ++++ + +Q I L L ++ ++ D
Sbjct: 660 VNSNSKQKEADAIDDTLSSKLKVKELSVIDGRRAQNCNILLSRLK-LSNDEIKRAILTMD 718
Query: 1331 REFLSTPSVIEFLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNELQRADQ 1390
+ ++E L K F P +D +D + + + + + +AD+
Sbjct: 719 EQEDLPKDMLEQLLK-------------FVPEKSD------IDLLEEHKHELDRMAKADR 759
Query: 1391 LYVEFM-INLQPYWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDV 1449
E IN ++ R++++ + + +++ K+ I + + +S +L+ + +V
Sbjct: 760 FLFEMSRIN---HYQQRLQSLYFKKKFAERVAEVKPKVEAIRSGSEEVFRSGALKQLLEV 816
Query: 1450 ILAVGNYMNDSSK-QAQGFKLSTLQRLTFIKDE-KNSMTFLNYVEKIIRENYPEYSHFVE 1507
+LA GNYMN + A GFK+S+L ++ K ++T L+Y+ I+ YP + E
Sbjct: 817 VLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPSVLNLNE 876
Query: 1508 ELEPIFSVTKISIEQLVTDCKEFSQSVINVERSIEIGNLSDPSKFHPLDRVLNKVVPVLP 1567
EL I K+++ +L + + VE +E P P D+ ++ V +
Sbjct: 877 ELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQPP---QPGDKFVSVVSQFIT 933
Query: 1568 EARKKADLLSDEIKLSLLEFENLMKKFGEDANDKFSKNSFFQKFADFITEFKKAKTHNVK 1627
A + D + + F +K FGE+A K + FF F F+ +AK N
Sbjct: 934 VASFSFSDVEDLLAEAKDLFTKAVKHFGEEAG-KIQPDEFFGIFDQFLQAVSEAKQENEN 992
Query: 1628 LXXXXXXXXXXKKMIEDQQRKQQEA---DSKATAKNLSTSQEPSDDRDDIEKLLDKLKNA 1684
+ KK E+++R + EA + + + + ++E S++ + + L+ L++
Sbjct: 993 M---------RKKKEEEERRARMEAQLKEQRERERKMRKAKENSEESGEFDDLVSALRSG 1043
Query: 1685 APSKGDPSSTRKRALARKKLLDGKSGAS 1712
D S ++ RK++ + + +S
Sbjct: 1044 EVFDKDLSKLKRN---RKRITNQMTDSS 1068
>CE23783 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1034
Score = 90.1 bits (222), Expect = 3e-17
Identities = 112/517 (21%), Positives = 217/517 (41%), Gaps = 82/517 (15%)
Query: 1210 PKATVTSPLLPQSPSLFERYPRPKKKLKQLHWEKI--DNAGDSIWKNAQAEKVADDLFER 1267
P +TSP + P P +K L+W+++ D ++W EK+ L
Sbjct: 558 PIGGLTSP----PKDALKNVPEPPGNMKTLNWQRLTLDKTRGTVWDGIDDEKIYKQLD-- 611
Query: 1268 GVLSQLEKAFAA------RETKSLKG----KSKEANEKITFLSRDVSQQFGINLHMFSNL 1317
L++L FAA +T +L G + ++AN IT + Q I L L
Sbjct: 612 --LTELSGCFAASSSHKDEDTDTLYGTINRRPQQAN--ITVIDPRRYQNCTIMLSKLK-L 666
Query: 1318 DVKDVVGKVMKCDREFLSTPSVIEFLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKP 1377
K++ +M D + +IE + K F P E +T ++++
Sbjct: 667 SHKEIKQAMMSMDEKCKLPKDMIEQMLK-------------FMPTK---EELTQINESVQ 710
Query: 1378 PEKDPNELQRADQLYVEFMINLQPYWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCI 1437
P L AD+ E I+ P + R+R + +I ++ LV ++ + +A
Sbjct: 711 KHGSPTVLALADRYMYE--ISSIPRFEQRLRCLNIIRSFHDRVEALVPFIQVVLKATSSC 768
Query: 1438 EQSESLRHVFDVILAVGNYMNDSSK--QAQGFKLSTLQRLTFIKDE-KNSMTFLNYVEKI 1494
+Q++ R + +ILA+GNY+N + A GF+++++ +L +K+ +N L+++
Sbjct: 769 QQNKRFRQILTIILAIGNYLNFGKRNGNAYGFEMASINKLADVKNALRNDRNLLHFLVNF 828
Query: 1495 IRENYPEYSHFVEELEPIFSVTKISIEQLVTDCKEFSQSVINVERSIEIGNLSDPSKFHP 1554
I + YP+ + F ++ + + S + + + ++++ V + E+ L +K
Sbjct: 829 IEKKYPDLTKFKKDFATVTEAARFSQSETAAEIRNLEEALLIVRK--ELNLLESTTKVE- 885
Query: 1555 LDRVLNKVVPVLPEARKKADLLSDEIKLSLLEFENLMKKFGEDANDKFS----------- 1603
L + +P PE + A + I+ + E+ NL K F E N KFS
Sbjct: 886 ----LPEHIP--PENDRFALVAKAFIEKATAEYHNLDKMFREMKN-KFSDCAKYFCYSPS 938
Query: 1604 -----KNSFFQKFADFITEFKKAKTHNVKLXXXXXXXXXXKKMIEDQQRKQQEADSKATA 1658
FF F+ F + ++ +L ++ E+++ K+Q A
Sbjct: 939 GGVPVPEEFFSVINKFLNTFNE---YHQQLWA---------EVEEEEKIKRQTIARSFLA 986
Query: 1659 KNLSTSQEPSDDRDDIEKLLDKLKNAAPSKGDPSSTR 1695
K +T ++ + D E+L+ L++ K + S R
Sbjct: 987 KKSTTRRKENHKERDFEQLISALQSGDIFKEELSRLR 1023
>7290137 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1429
Score = 89.0 bits (219), Expect = 7e-17
Identities = 114/532 (21%), Positives = 226/532 (42%), Gaps = 89/532 (16%)
Query: 1207 ANTPKATVTSPLLPQSPSLF---ERYPRPKKKLKQLHWEKIDNAG--DSIWKNAQAEKVA 1261
A P ++ + P P + + P+P LK +W K+ +A ++W K
Sbjct: 874 APPPPPSMAQTMAPAPPKVDLPKKNVPQPTNPLKSFNWSKLPDAKLQGTVWSELDESK-- 931
Query: 1262 DDLFERGVLSQLEKAFAARET----------KSLKGKSKEANEKI-TFLSRDVSQQFGIN 1310
L+ L ++K F+A + + L+ K A +K+ + + +Q I
Sbjct: 932 --LYNNMELESIDKLFSAYQKNGVSATDGSYEDLRVTGKAAKQKVLSVIDGRRAQNCTI- 988
Query: 1311 LHMFSNLDVKDVVGKVMKCDREFLSTPSVIEFLSKPTIIEVTNNLARYFNPYSTDWEGVT 1370
+ S L + D M+ + LS S ++ +++ L + F P + E
Sbjct: 989 --LLSKLKMSD-----MEISKAILSMDS-----NEQLQLDMVEQLLK-FTPSA---EERA 1032
Query: 1371 SVDDAKPPEKDPNELQRADQLYVEFMINLQPYWGSRMRAITMITTYEKDYSDLVTKLRKI 1430
+D+ +D L RAD+ E I+ P++ R++++ + +DLV ++ +
Sbjct: 1033 LLDEHS---EDIESLARADRFLYE--ISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSV 1087
Query: 1431 DRAVQCIEQSESLRHVFDVILAVG--------------------NYMNDSSK-QAQGFKL 1469
A + + +S LR + +++LA+G NYMN ++ A GF+L
Sbjct: 1088 MEASREVARSRRLRKLLELVLALGMIHCPFAKHSITQTTSIPPGNYMNRGARGNASGFRL 1147
Query: 1470 STLQRLTFIKDEK-NSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKISIEQLVTDCK 1528
++L RL K T L+Y+ ++I + + +++ + +K+S+ ++ D +
Sbjct: 1148 ASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDIQ 1207
Query: 1529 EFSQSVINVERSIEIGNLSDPSKFHPLDRVLNKVVPVLPEARKKADL----LSDEIKLSL 1584
+ +V R IE S P++ ++ +PV+ E +A + L D+ +
Sbjct: 1208 MLRTGLADVAREIEFHRSSGPAQQG------DRFLPVMREFHAQASVRFAELEDKFQDMK 1261
Query: 1585 LEFENLMKKFGEDANDKFSKNSFFQKFADFITEFKKAKTHNVKLXXXXXXXXXXKKMIED 1644
F+ ++ FGED + + FF F F+ F +A+ N ++ E+
Sbjct: 1262 TRFDRAVRLFGEDGS-VLQPDEFFGIFDSFLAAFAEARHDN---------ESFRRRQEEE 1311
Query: 1645 QQRKQQEADSKATAKNLSTSQEPSDDRDDIEKLLDKLKNAAPSKGDPSSTRK 1696
++R +QEA+ K K + + + + L LK+ + S GDP S K
Sbjct: 1312 EKRAKQEAELK---KRTIERKNKTGLMTSVARNLG-LKSGS-SNGDPDSPAK 1358
>CE27278 [TZ] KOG1923 Rac1 GTPase effector FRL
Length = 1088
Score = 86.7 bits (213), Expect = 3e-16
Identities = 118/502 (23%), Positives = 204/502 (40%), Gaps = 74/502 (14%)
Query: 1233 KKKLKQLHWEKIDNAGDSIWKNAQAEKVADDLF-ERGVLSQLEKAFA-ARETKSLKGKSK 1290
K KL QL+W + KN EK+ D+L E+ S+LE+ F A+ T L
Sbjct: 590 KNKLPQLNWTAMKPMQA---KNTVFEKLNDELIIEKLDFSKLEEMFKLAQPTLGLAEPKS 646
Query: 1291 EAN-------------------EKITFLSRDVSQQFGINLHMFSNLDVKDVVGKVMKCDR 1331
E + K T L Q I + +D K ++ V + +
Sbjct: 647 EQSVIGQVSPGSTTSAAGTSSARKNTLLDTKRLQNVAITRRKVA-MDAKSIMAAVHQLNL 705
Query: 1332 EFLSTPSVIEFLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNELQRADQL 1391
LS V + LS+ I+ Y +T+ E S+++ + L ++L
Sbjct: 706 SALSAEKV-DILSR--ILPTDEERKLYAGKKTTESEN--SMENLSEDDNFVAALCEIERL 760
Query: 1392 YVEFMINLQPYWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVIL 1451
++ + +++ +++ L + + A +C +++ V +VIL
Sbjct: 761 E------------HKLAVMRVMSEFDESAGLLEPQFTHVTAASKCAREAQLFHGVLEVIL 808
Query: 1452 AVGNYMNDSSK-QAQGFKLSTLQRLTFIK-DEKNSMTFLNYVEKIIRENYPEYSHFVEEL 1509
A GNYMN + A GFKLS+L L +K S+T L+ + I +N P F E+L
Sbjct: 809 AFGNYMNSGKRGGAYGFKLSSLDSLAILKAPADRSLTLLHMIVAEIEKNLPHLKTFSEQL 868
Query: 1510 EPIFSVTKISIEQLVTDCKEFSQSVINVERSIEIGNLSDPSKFHPLDRVLNKVVPVLPEA 1569
+ + T + + + TD KE + E+ E+ P
Sbjct: 869 KFVDKATSVQWDSVQTDMKELAAGFKMAEKEQELKGTDCPEALSTF---------TASRK 919
Query: 1570 RKKADLLSDEIKLSLLEFENLMKKFGEDANDKFSKNSFFQKFADFITEFKKAKTHNVKLX 1629
+K AD L +L+ F++ + +GE+ S FFQK A F+ ++K + N
Sbjct: 920 QKMAD-LEQAFQLAASSFKDCCEFYGENEKST-SPTVFFQKLAHFVQNYQKCRGEN---- 973
Query: 1630 XXXXXXXXXKKMIEDQQRKQQEADSKATAKNLSTSQEPSDDRDDI-EKLLDKLKNAAPSK 1688
K +E +R+Q+EA+ + A+ ST S ++D + +L +K+ K
Sbjct: 974 -------EAKAALE--KRRQEEAERR--ARVASTKSSASSEQDQLMMELAEKVGGMGIGK 1022
Query: 1689 ---GDPSSTRKRALARKKLLDG 1707
G STR +KL++G
Sbjct: 1023 RPRGKIDSTRMDHGDFEKLMNG 1044
>Hs5174401 [TZ] KOG1923 Rac1 GTPase effector FRL
Length = 463
Score = 85.9 bits (211), Expect = 6e-16
Identities = 92/383 (24%), Positives = 164/383 (42%), Gaps = 49/383 (12%)
Query: 1250 SIWKNAQAEKVADDLFERGVLSQLEKAFAAR------ETKSLKGKS-KEANEKITFLSRD 1302
+++ EKV +L +S E+ F + + +LK K+ ++A K T + +
Sbjct: 17 TVFTELNDEKVLQELD----MSDFEEQFKTKSQGPSLDLSALKSKAAQKAPSKATLIEAN 72
Query: 1303 VSQQFGINLHMFSNLDVKDVVGKVMKCDREFLSTPSVIEFLSKPTIIEVTNNLARYFNPY 1362
++ I L NL + + + D + L ++FL L F P
Sbjct: 73 RAKNLAITLRK-GNLGAERICQAIEAYDLQALG----LDFLE----------LLMRFLPT 117
Query: 1363 STDWEGVTSVDDAKPPEKDPNELQRADQLYVEFMINLQ--PYWGSRMRAITMITTYEKDY 1420
+ +T + + P ++ +E R FM+ P RM +T + +
Sbjct: 118 EYERSLITRFEREQRPMEELSEEDR-------FMLCFSRIPRLPERMTTLTFLGNFPDTA 170
Query: 1421 SDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMNDSSK-QAQGFKLSTLQRLTFIK 1479
L+ +L I A I+ S+ LR + +++LA GNYMN S + A GF+L +L L +K
Sbjct: 171 QLLMPQLNAIIAASMSIKSSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMK 230
Query: 1480 DEKNSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKISIEQLVTDCKEFSQSVINVER 1539
T L+Y+ K+I E YP+ + F +L + +S++ ++ D + + + +R
Sbjct: 231 STDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGSVSLDSVLADVRSLQRGLELTQR 290
Query: 1540 SIEIGNLSDPSKFHPLDRVLNKVVPVLPEARKKADLLSDEIKLSLLEFENLMKKFGEDAN 1599
E D L L P + D L + K + FE++++ FGE+
Sbjct: 291 --EFVRQDD---CMVLKEFLRANSPTM-------DKLLADSKTAQEAFESVVEYFGENPK 338
Query: 1600 DKFSKNSFFQKFADFITEFKKAK 1622
S FF F+ FI +KKA+
Sbjct: 339 TT-SPGLFFSLFSRFIKAYKKAE 360
>Hs13569895 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous
Length = 691
Score = 83.6 bits (205), Expect = 3e-15
Identities = 75/301 (24%), Positives = 142/301 (46%), Gaps = 43/301 (14%)
Query: 1231 RPKKKLKQLHWEKIDNAGDSIWKNAQAEKVADDLFER-GVLSQLEKAFAAR--------- 1280
+P+ +++L+W KI + +N KV ++ +E +L +LE F +
Sbjct: 378 KPEISMRRLNWLKI--RPHEMTENCFWIKVNENKYENVDLLCKLENTFCCQQKERREEED 435
Query: 1281 --ETKSLKGKSKEANEKITFLSRDVSQQFGINLHMFSNLDVKDVVGKVMKCDREFLSTPS 1338
E KS+K K KE + FL ++Q I L F + +++ +++ D L+
Sbjct: 436 IEEKKSIKKKIKE----LKFLDSKIAQNLSIFLSSF-RVPYEEIRMMILEVDETRLAESM 490
Query: 1339 VIEFLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNELQRADQLYVEFMIN 1398
+ + E N+L+++ + YS E PE+ +V M N
Sbjct: 491 IQNLIKHLPDQEQLNSLSQFKSEYSNLCE----------PEQ-----------FVVVMSN 529
Query: 1399 LQPYWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMN 1458
++ R+ AI +E+ +++ + + A + I++S+S + +++L +GNYMN
Sbjct: 530 VKRL-RPRLSAILFKLQFEEQVNNIKPDIMAVSTACEEIKKSKSFSKLLELVLLMGNYMN 588
Query: 1459 DSSKQAQ--GFKLSTLQRLTFIKDEKNSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVT 1516
S+ AQ GF LS+L +L K T L+++ +I E YP+ +FV++LEP+ +
Sbjct: 589 AGSRNAQTFGFNLSSLCKLKDTKSADQKTTLLHFLVEICEEKYPDILNFVDDLEPLDKAS 648
Query: 1517 K 1517
K
Sbjct: 649 K 649
>Hs22060175 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 796
Score = 82.8 bits (203), Expect = 5e-15
Identities = 106/514 (20%), Positives = 217/514 (41%), Gaps = 74/514 (14%)
Query: 1227 ERYPRPKKKLKQLHWEKI--DNAGDSIWKNAQAEKVADDLFERGVLSQLEKAFAARE--- 1281
+R P+P LK +W K+ + ++W +V F L EK F+A +
Sbjct: 315 KRVPQPSHPLKSFNWVKLNEERVPGTVWNEIDDMQV----FRILDLEDFEKMFSAYQRHQ 370
Query: 1282 ---TKSLKGKSKEANEKITFLSRDVSQQFGINLHMFSN---------LDVKDVVGKVMKC 1329
T + K + E I SR V + I+ N L +++ ++K
Sbjct: 371 ELITNPSQQKELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKM 430
Query: 1330 DREFLSTPSVIEFLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNELQRAD 1389
D + ++E L K F P +D +D + + + + RAD
Sbjct: 431 DEQEDLAKDMLEQLLK-------------FIPEKSD------IDLLEEHKHEIERMARAD 471
Query: 1390 QLYVEFMINLQPYWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDV 1449
+ E ++ ++ R++A+ +++ ++ K+ I A + + +S+ LR + +V
Sbjct: 472 RFLYE--MSRIDHYQQRLQALFFKKKFQERLAEAKPKVEAILLASRELVRSKRLRQMLEV 529
Query: 1450 ILAVGNYMNDSSK-QAQGFKLSTLQRLTFIKDE-KNSMTFLNYVEKIIRENYPEYSHFVE 1507
ILA+GN+MN + A GF++++L ++ K +++ L+Y+ I+ +++P+ +
Sbjct: 530 ILAIGNFMNKGQRGGAYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPS 589
Query: 1508 ELEPIFSVTKISIEQLVTDCKEFSQSV--INVERSIEIGNLSDPSKFHPLDRVLNKVVPV 1565
EL+ + K+++ +L + + + + VE + + +PS +K VPV
Sbjct: 590 ELQHLPEAAKVNLAELEKEVGNLRRGLRAVEVELEYQRRQVREPS---------DKFVPV 640
Query: 1566 LPEARKKADL----LSDEIKLSLLEFENLMKKFGEDANDKFSKNSFFQKFADFITEFKKA 1621
+ + + L D++ + +F + FGE + K + FF F F+ F +A
Sbjct: 641 MSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEH-DSKMQPDEFFGIFDTFLQAFSEA 699
Query: 1622 KTHNVKLXXXXXXXXXXKKM--IEDQQRKQQEADSKATAKNLSTSQEPSDDRDDI----- 1674
+ + +M + +QR+++ + +S E + DD+
Sbjct: 700 RQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQRKVLAAGSSLEEGGEFDDLVSALR 759
Query: 1675 -----EKLLDKLKNAAPSKGDPS--STRKRALAR 1701
+K L KLK + G + TR+RA+ R
Sbjct: 760 SGEVFDKDLCKLKRSRKRSGSQALEVTRERAINR 793
>Hs20533991 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1119
Score = 80.1 bits (196), Expect = 3e-14
Identities = 125/537 (23%), Positives = 209/537 (38%), Gaps = 77/537 (14%)
Query: 1233 KKKLKQLHWEKIDN----AGDSIWKNAQAE--------KVADDLFERGVLSQLEKAFAAR 1280
KK+++ W+ I +IW A + K ++LF G K+ R
Sbjct: 70 KKRMRSFFWKTIPEEQVRGKTNIWTLAARQEHHYQIDTKTIEELF--GQQEDTTKSSLPR 127
Query: 1281 ETKSLKGKSKEANEKITFLSRDVSQQFGINLHMFSNLDVKDVVGKVMKCDREFLSTPSVI 1340
++L +EA E+IT L S GI L F + +V + + E + ++
Sbjct: 128 RGRTLNSSFREAREEITILDAKRSMNIGIFLKQFKK-SPRSIVEDIHQGKSEHYGSETLR 186
Query: 1341 EFLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNELQRADQLYVEFMINLQ 1400
EFL F P S + V K D ++L AD ++ +I +
Sbjct: 187 EFLK--------------FLPESEE------VKKLKAFSGDVSKLSLADS-FLYGLIQV- 224
Query: 1401 PYWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMNDS 1460
P + R+ A+ + + S L T + + A++ + E L + ++L GN MN
Sbjct: 225 PNYSLRIEAMVLKKEFLPSCSSLYTDITVLRTAIKELMSCEELHSILHLVLQAGNIMNAG 284
Query: 1461 --SKQAQGFKLSTLQRLTFIKDEKNSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKI 1518
+ A GFKLS+L +L K K M L++V + ++ +F E+L + ++
Sbjct: 285 GYAGNAVGFKLSSLLKLADTKANKPGMNLLHFVAQEAQKKDTILLNFSEKLHHVQKTARL 344
Query: 1519 SIEQLVTDCKEFSQSVINVERSIEIGNLSDPSKFHPLDRVLNKVVPVLPEARKKADLLSD 1578
S+E + +++ +I+ D ++ L + L E L D
Sbjct: 345 SLENTEAELHLLFVRTKSLKENIQ----RDGELCQQMEDFLQFAIEKLRELECWKQELQD 400
Query: 1579 EIKLSLLEFENLMKKFGEDANDKFSKNSFFQKFADFITEFKKAKTHNVKLXXXXXXXXXX 1638
E +L++F F ED + FQ F DF T+F KA N
Sbjct: 401 EA-YTLIDF------FCEDKKT-MKLDECFQIFRDFCTKFNKAVKDN--------HDREA 444
Query: 1639 KKMIEDQQRKQQEADSKATAKNLSTSQEPSDDRDDIEKLLDK-----LKNAAPSKGDPSS 1693
+++ + Q+ K+QE ++ A + S +D+E L K L P PSS
Sbjct: 445 QELRQLQRLKEQEQKQRSWATGELGAFGRSSSENDVELLTKKGAEGLLPFLHPRPISPSS 504
Query: 1694 TRKRA--LARKKLLDGKSGASIFDNITADSTIEAFVEQNRTLTESPTAKKSASLPET 1748
R R +L G S AD + F+E + E P K SLP +
Sbjct: 505 PSYRPPNTRRSRLSLGPS---------ADRELLTFLESSTGSPEEP--NKFHSLPRS 550
>At5g07780 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 464
Score = 79.7 bits (195), Expect = 4e-14
Identities = 90/406 (22%), Positives = 170/406 (41%), Gaps = 47/406 (11%)
Query: 1217 PLLPQSPSLFERYPRPKKKLKQLHWEKIDNA-GDSIWKNAQAEKVADDLFERGVLSQLEK 1275
P P P R P+ K LK LHW K A S+W Q + D+ + +L +E
Sbjct: 59 PPPPPLPRPCSRPPKTKCSLKPLHWVKKTRALPGSLWDELQRRQECRDIEDEQILCAIEL 118
Query: 1276 AFAARET---KSLKGKSKEANEKITFLSRDVSQQFGINLHMFSNLDVKDVVGKVMKCDRE 1332
+ + ET K K K EK+ + + I L M N+ + D++ M D
Sbjct: 119 SVSEIETIFSLGAKPKPKPEPEKVPLIDLRRATNTEIRL-MLLNIRLPDMIAAAMAMDES 177
Query: 1333 FLSTPSVIEFLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNELQRADQLY 1392
L IE NL F P D + + + D ++ Q Y
Sbjct: 178 RLDDFDQIE------------NLINLF-PTKEDMKFLLTYTG------DKGNCEQLFQ-Y 217
Query: 1393 VEFMINLQPYWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILA 1452
++ ++ + P S++R + + + L L ++ A + I S+ L+ + + IL
Sbjct: 218 LQEVVKV-PRVESKLRVFSFKIQFGTQITKLTKGLNAVNSACEEIRTSQKLKDIMENILC 276
Query: 1453 VGNYMNDSS--KQAQGFKLSTLQRLTFIKDEKNSMTFLNYVEKIIRENYPEYSHFVEELE 1510
+GN +N + +A GF+L +L L+ + + + MT ++Y+ K++ + F ++LE
Sbjct: 277 LGNILNQGTGRGRAVGFRLDSLLILSETRADNSKMTLMHYLCKVLASKASDLLDFHKDLE 336
Query: 1511 PIFSVTKISIEQLVTDCKEFSQSVINVERSIEIGNLSDP--SKFHPL--------DRVLN 1560
+ S +KI ++ L + + ++ + +++ + P F L + +
Sbjct: 337 SLESASKIQLKSLAEEIQAITKGLEKLKQELTASETDGPVSQVFRKLLKEFISNAETQVA 396
Query: 1561 KVVPVLPEARKKADLLS---------DEIKLSLLEFENLMKKFGED 1597
V+ + AR A+ L+ +++ +LL F L KK E+
Sbjct: 397 TVMALYYPARGNAEALAHYFGYHYPFEQVTATLLSFIRLFKKAHEE 442
>7294416 [TZ] KOG1923 Rac1 GTPase effector FRL
Length = 1043
Score = 75.5 bits (184), Expect = 7e-13
Identities = 100/457 (21%), Positives = 180/457 (38%), Gaps = 56/457 (12%)
Query: 1220 PQSPSLFERYPRPKKKLKQLHWE--KIDNAGDSIWKNAQAEKVA--------DDLFERGV 1269
P +R K KL L+W K + +I+ EK+ ++ F+ G+
Sbjct: 551 PDGAMTIKRKVPTKYKLPTLNWIALKPNQVRGTIFNELDDEKIFKQIDFNEFEERFKIGI 610
Query: 1270 LSQLEKAFAARETKSLKGKSKEAN--EKITFLSRDVSQQFGINLHMFSNLDVKDVVGKVM 1327
L E SK + ++ L + I+ + + DV+ +
Sbjct: 611 GGALRNGSNGTEVDGSLQSSKRFKRPDNVSLLEHTRLRNIAISRRKLG-MPIDDVIAAIH 669
Query: 1328 KCDREFLSTPSVIEFLSK--PTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNEL 1385
D + LS +V E L K PT EV + + Y + + D E+D L
Sbjct: 670 SLDLKKLSLENV-ELLQKMVPTDAEVKS-----YKEYIIERK-----DQQLLTEEDKFML 718
Query: 1386 QRADQLYVEFMINLQPYWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRH 1445
Q + + + + Y G+ + ++ +I+ +++ I A ++QS +
Sbjct: 719 QLSRVERISSKLAIMNYMGNFVDSVHLISP----------QVQSIAGASTSLKQSRKFKA 768
Query: 1446 VFDVILAVGNYMNDSSK-QAQGFKLSTLQRLTFIKDEKNSMTFLNYVEKIIRENYPEYSH 1504
V +++LA GNY+N + + A GFKL +L L K + L+Y+ IR +PE +
Sbjct: 769 VLEIVLAFGNYLNSNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRAKFPELLN 828
Query: 1505 FVEELEPIFSVTKISIEQLVTDCKEFSQSVINVERSIEIGNLSDPSKFHPLDRVLNKVVP 1564
F EL +++E +V D +E + + V + E+ ++ H L LN
Sbjct: 829 FESELYGTDKAASVALENVVADVQELEKGMDLVRKEAEL--RVKGAQTHILRDFLN---- 882
Query: 1565 VLPEARKKADLLSDEIKLSLLEFENLMKKFGEDANDKFSKNSFFQKFADFITEFKKAKTH 1624
+ K + +++ + F+ ++ FG D++ +FF F FK+
Sbjct: 883 ---NSEDKLKKIKSDLRHAQEAFKECVEYFG-DSSRNADAAAFFALIVRFTRAFKQHDQE 938
Query: 1625 N-VKLXXXXXXXXXXKKMIEDQ--------QRKQQEA 1652
N +L K DQ Q+KQQEA
Sbjct: 939 NEQRLRLEKAAALAASKKENDQVLMRNKVNQKKQQEA 975
>At5g07770 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 721
Score = 67.4 bits (163), Expect = 2e-10
Identities = 63/324 (19%), Positives = 136/324 (41%), Gaps = 38/324 (11%)
Query: 1233 KKKLKQLHWEKIDNA-GDSIWKNAQAEKVADDLFERGVLSQLEKAFAARETKSLKGKSKE 1291
+ LK LHW KI A S+W Q + + ++E F+ K + K
Sbjct: 189 RSSLKPLHWVKITRALQGSLWDELQIQYGESQTAIELDVPEIETLFSV----GAKPRPKP 244
Query: 1292 ANEKITFLSRDVSQQFGINLHMFSNLDVKDVVGKVMKCDREFLSTPSVIEFLSKPTIIEV 1351
EK+ + + +NL + + + D++ VM D L + + E
Sbjct: 245 KPEKVPLIDLKRANNTIVNLKILK-MPLPDMMAAVMAMDESVLDVDQIENLIQLCPTKEE 303
Query: 1352 TNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNELQRADQLYVEFMINLQPYWGSRMRAIT 1411
L Y +T L +++Q +E M P + +++R ++
Sbjct: 304 MELLKNYTGDKAT--------------------LGKSEQCLLELM--KVPRFEAKLRVLS 341
Query: 1412 MITTYEKDYSDLVTKLRK----IDRAVQCIEQSESLRHVFDVILAVGNYMNDSSKQ--AQ 1465
++ + +TK RK ++ A + + S+ L+ + +IL +GN +N + + A
Sbjct: 342 ----FKIPFGTKITKFRKMLNVVNSACEEVRSSQMLKEIMKIILFLGNTLNQGTARGSAV 397
Query: 1466 GFKLSTLQRLTFIKDEKNSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKISIEQLVT 1525
GF+L +L L+ + + N MT ++Y+ K++ + F ++L+ + S +I+++ L
Sbjct: 398 GFRLDSLLILSETRADNNKMTLMHYLCKVLASKAADLLDFHKDLQSLESTLEINLKSLAE 457
Query: 1526 DCKEFSQSVINVERSIEIGNLSDP 1549
+ ++ + +++ + P
Sbjct: 458 EIHAITKGLEKLKQELTASETDGP 481
>7295293 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1034
Score = 67.0 bits (162), Expect = 3e-10
Identities = 108/495 (21%), Positives = 191/495 (37%), Gaps = 84/495 (16%)
Query: 1211 KATVTSPLLPQSPSLFERYPRPKKKLKQLHWEKIDN----AGDSIWK----NAQAEKVAD 1262
+A T+ LLPQ + P PK K+K ++W KI + +IW N Q + D
Sbjct: 315 EAVATAILLPQQDT-----PAPKAKMKTINWGKIPHNKVLGKQNIWSIVASNHQDSPMQD 369
Query: 1263 -DLFERGVLSQLEKAFAARETK----------------SLKGKSKEANEKITFLSRDVSQ 1305
D E L L+ A A K +L KSK+ + +IT L S
Sbjct: 370 IDWNEMEGLFCLQTASAQGSPKLGRDGSQAAAGSNGCDTLDRKSKKESTEITLLDGKRSL 429
Query: 1306 QFGINLHMFSNLDVKDVVGKVMKCDREFLSTPSVIEFLSKPTIIEVTNNLARYFNPYSTD 1365
I L F S +I+ + + E+ R +
Sbjct: 430 NVNIFLKQFRT------------------SNDDIIQLIRQGAHEEIGAERLRGLLKIMPE 471
Query: 1366 WEGVTSVDDAKPPEKDPNELQRADQLYVEFMINLQPYWGSRMRAITMITTYEKDYSDLVT 1425
V +D K D L A++ ++ + P + R+ ++ + + + + L
Sbjct: 472 ---VDELDMLKGFNGDKARLGNAEKFLLQLLE--VPNYKLRIESMLLKEEFAANVAYLEP 526
Query: 1426 KLRKIDRAVQCIEQSESLRHVFDVILAVGNYMNDS--SKQAQGFKLSTLQRLTFIKDEKN 1483
+ + A + +++L+ V +++ GN++N + A G KLS+LQ+LT I+ K
Sbjct: 527 CINSMLYAGDDLLNNKTLQEVLYMVVVAGNFLNSGGYAGNAAGVKLSSLQKLTDIRANKP 586
Query: 1484 SMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKISIEQLVTDCKEFSQSVINVERSIEI 1543
M +++V + PE F +L + S +K + EQ+ + + + R IE
Sbjct: 587 GMNLIHFVALQAEKRNPELLQFTGQLSNLESASKTTSEQINNEINTLDGRIRRIARQIEQ 646
Query: 1544 GNLSDPSKFHPLD--RVLNKVVPVLPEARKKADLLSDEIKLSLLEFENLMKKFGEDANDK 1601
K D + + VL K+ + ++L + EF F +DA
Sbjct: 647 PATDVDIKEQMADFLQAAESELSVLQAGMKQV----ESMRLKMSEF------FCDDA-AT 695
Query: 1602 FSKNSFFQKFADFITEFKKAKTHNVKLXXXXXXXXXXKKMIEDQQ----RKQQEADSKAT 1657
F F+ F +F +FK+A N ++ ++QQ RKQ+E
Sbjct: 696 FRLEECFKIFHNFCDKFKQAVKEN------------ERRQQQEQQATLRRKQREEQLARR 743
Query: 1658 AKNLSTSQEPSDDRD 1672
A+ + + P D +
Sbjct: 744 ARQIGQAGTPVSDSE 758
>7295751 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1059
Score = 60.5 bits (145), Expect = 2e-08
Identities = 63/287 (21%), Positives = 120/287 (40%), Gaps = 29/287 (10%)
Query: 1397 INLQPYWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNY 1456
I+L R+ I +E+ + L KL + + Q + +SE L+ VF +IL +GNY
Sbjct: 771 ISLISMASERISCIVFQAEFEESVTLLFRKLETVSQLSQQLIESEDLKLVFSIILTLGNY 830
Query: 1457 MNDSSK---QAQGFKLSTLQRLTFIKDEKNSMTFLNY-VEKIIRENYPEYSHFVEELEPI 1512
MN ++ QA GF L L +L +K +++ T L++ V I + E H +E PI
Sbjct: 831 MNGGNRQRGQADGFNLDILGKLKDVKSKESHTTLLHFIVRTYIAQRRKEGVHPLEIRLPI 890
Query: 1513 FSVTKISIEQLVTDCKEFSQSVINVER--------SIEIGNLSDPSKFHPLDRVLNKVVP 1564
+ D +E Q + ++ + + ++ S P P + + V
Sbjct: 891 PEPADVE-RAAQMDFEEVQQQIFDLNKKFLGCKRTTAKVLAASRPEIMEPFKSKMEEFVE 949
Query: 1565 VLPEARKKADLLSDEIK---LSLLEFENLMKKFGEDANDKFSKNSFFQKFADFITEFKKA 1621
++ K DE + L + F + K + + + FF+ + +F +FK
Sbjct: 950 GADKSMAKLHQSLDECRDLFLETMRFYHFSPKACTLTLAQCTPDQFFEYWTNFTNDFKDI 1009
Query: 1622 KTHNVKLXXXXXXXXXXKKMIEDQQRKQQEADSKATAKNLSTSQEPS 1668
+ ++ + +K ++A + + +N+ST E S
Sbjct: 1010 WKKEI------------TSLLNELMKKSKQAQIE-SRRNVSTKVEKS 1043
>Hs13399326 [TZ] KOG1925 Rac1 GTPase effector FHOS
Length = 418
Score = 59.3 bits (142), Expect = 6e-08
Identities = 66/338 (19%), Positives = 141/338 (41%), Gaps = 26/338 (7%)
Query: 1416 YEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMNDSSKQAQGFKLSTLQRL 1475
YE ++ L + + +E +++L + +LA+GN++N ++ A+ F+LS L+++
Sbjct: 52 YETTEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNGTN--AKAFELSYLEKV 109
Query: 1476 TFIKDEKNSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKISIEQLVTDCKEFSQSVI 1535
+KD + + L++V ++ EN+P+ S E+ I K+ +QL ++
Sbjct: 110 PEVKDTVHKQSLLHHVCTMVVENFPDSSDLYSEIGAITRSAKVDFDQL-------QDNLC 162
Query: 1536 NVERSIEIG--NLSDPSKFHPLDRVLNKVVPVLPEARKKADLLSDEIKLSLLEFENLMKK 1593
+ER + +L +K + ++ L + ++ +L + + F + +
Sbjct: 163 QMERRCKASWDHLKAIAKHEMKPVLKQRMSEFLKDCAERIIILKIVHRRIINRFHSFLLF 222
Query: 1594 FGED--ANDKFSKNSFFQKFADFITEFKKAK----THNVKLXXXXXXXXXXKKMIEDQQR 1647
G A + + N F + ++F E++ + K KMI D +
Sbjct: 223 MGHPPYAIREVNINKFCRIISEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITDSGK 282
Query: 1648 KQQEADSKATAKNLSTSQEPSDDRDDIEKLLDKLKNAAPSKGDPS-----STRKRALARK 1702
+ S + ++D + E + LK ++PS D + TR RA +R
Sbjct: 283 ---FSGSSPAPPSQPQGLSYAEDAAEHENMKAVLKTSSPSVEDATPALGVRTRSRA-SRG 338
Query: 1703 KLLDGKSGASIFDNITADSTIEAFVEQNRTLTESPTAK 1740
G N+T D+ E ++ T+ P+ +
Sbjct: 339 STSSWTMGTDDSPNVTDDAADEIMDRIVKSATQVPSQR 376
>At5g07760 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 832
Score = 59.3 bits (142), Expect = 6e-08
Identities = 50/223 (22%), Positives = 100/223 (44%), Gaps = 10/223 (4%)
Query: 1381 DPNELQRADQLYVEFMINLQPYWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQS 1440
D L + +Q ++E M P S++R + + +L L ++ A + I S
Sbjct: 564 DKATLGKCEQYFLELM--KVPGVESKLRVFSFKIHFGTQIKELNKGLNTVNSACEEIRTS 621
Query: 1441 ESLRHVFDVILAVGNYMNDSSKQ--AQGFKLSTLQRLTFIKDEKNSMTFLNYVEKIIREN 1498
+ L+ + +IL +GN +N + + A GFKL +L L+ +MT ++Y+ K++
Sbjct: 622 QKLKEIMKIILCLGNILNQGTARGSAVGFKLDSLLNLSEKCSANTNMTLMHYLCKVLASK 681
Query: 1499 YPEYSHFVEELEPIFSVTKISIEQLVTDCKEFSQSVINVERSIEIGNLSDPSKFHPLDRV 1558
+ F ++LE + S +KI ++ L + ++ + + + L+ P+ V
Sbjct: 682 ASDLLDFHKDLENLESASKIHLKSLAEEMVAITKGLQKLNQ-----ELTASESDGPISEV 736
Query: 1559 LNKVV-PVLPEARKKADLLSDEIKLSLLEFENLMKKFGEDAND 1600
K++ + A + +S + L+ FGED ND
Sbjct: 737 FRKLLKDFISVAETQVATVSSLYSSVGGNTDALVHYFGEDPND 779
>At3g25500 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1051
Score = 59.3 bits (142), Expect = 6e-08
Identities = 67/313 (21%), Positives = 130/313 (41%), Gaps = 42/313 (13%)
Query: 1232 PKKKLKQLHWEKIDNAGD--SIWKNAQAEKVADDLFERGVLSQLEKAFAARETKSLKGKS 1289
PK KLK LHW+K+ + D +W + ++ D +E F A+ + +S
Sbjct: 594 PKPKLKALHWDKVRASSDREMVWDHLRSSSFKLD------EEMIETLFVAKSLNNKPNQS 647
Query: 1290 K--------EANEKITFLSRDVSQQFGINLHMFSNLDVKDVVGKVMKCDREFLSTPSVIE 1341
+ N++ L +Q I L N+ +++V +++ + + L T E
Sbjct: 648 QTTPRCVLPSPNQENRVLDPKKAQNIAILLRAL-NVTIEEVCEALLEGNADTLGT----E 702
Query: 1342 FLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNELQRADQLYVEFMINLQP 1401
L + T R Y+ D P +L A++ +++ M+++ P
Sbjct: 703 LLESLLKMAPTKEEERKLKAYNDD---------------SPVKLGHAEK-FLKAMLDI-P 745
Query: 1402 YWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMNDSS 1461
+ R+ A+ + +E + L ++ A + + S + + +L GN MN +
Sbjct: 746 FAFKRVDAMLYVANFESEVEYLKKSFETLEAACEELRNSRMFLKLLEAVLKTGNRMNVGT 805
Query: 1462 KQ--AQGFKLSTLQRLTFIKDEKNSMTFLNY-VEKIIRENYPEYSHFVEELEPIFSVTKI 1518
+ A FKL TL +L +K T L++ V++IIR S + + I K+
Sbjct: 806 NRGDAHAFKLDTLLKLVDVKGADGKTTLLHFVVQEIIRAEGTRLSGNNTQTDDI-KCRKL 864
Query: 1519 SIEQLVTDCKEFS 1531
++ + + C E S
Sbjct: 865 GLQVVSSLCSELS 877
>Hs20561733 [TZ] KOG1925 Rac1 GTPase effector FHOS
Length = 1164
Score = 57.8 bits (138), Expect = 2e-07
Identities = 39/193 (20%), Positives = 90/193 (46%), Gaps = 12/193 (6%)
Query: 1359 FNPYSTDWEGVTSVDDAKPPEKDPNELQRADQLYVE--------FMINLQPYWG--SRMR 1408
F+ ++ +G+ + P E++ +++ A + F++ L G +R++
Sbjct: 723 FDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGLAARLQ 782
Query: 1409 AITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMNDSSKQAQGFK 1468
Y+ ++ L + ++ + Q+ + R + +LAVGN++N S Q+ GF+
Sbjct: 783 LWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGS--QSSGFE 840
Query: 1469 LSTLQRLTFIKDEKNSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKISIEQLVTDCK 1528
LS L++++ +KD + L+++ ++ + PE S E+ + K+ EQL +
Sbjct: 841 LSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLG 900
Query: 1529 EFSQSVINVERSI 1541
+ + E S+
Sbjct: 901 QLERRSRAAEESL 913
>Hs7019375 [TZ] KOG1925 Rac1 GTPase effector FHOS
Length = 1164
Score = 57.0 bits (136), Expect = 3e-07
Identities = 39/193 (20%), Positives = 90/193 (46%), Gaps = 12/193 (6%)
Query: 1359 FNPYSTDWEGVTSVDDAKPPEKDPNELQRADQLYVE--------FMINLQPYWG--SRMR 1408
F+ ++ +G+ + P E++ +++ A + F++ L G +R++
Sbjct: 723 FDEFAVSKDGIEKLLTMMPTEEERQKIEGAQLANPDIPLGPAENFLMTLASIGGLAARLQ 782
Query: 1409 AITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMNDSSKQAQGFK 1468
Y+ ++ L + ++ + Q+ + R + +LAVGN++N S Q+ GF+
Sbjct: 783 LWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGS--QSSGFE 840
Query: 1469 LSTLQRLTFIKDEKNSMTFLNYVEKIIRENYPEYSHFVEELEPIFSVTKISIEQLVTDCK 1528
LS L++++ +KD + L+++ ++ + PE S E+ + K+ EQL +
Sbjct: 841 LSYLEKVSDVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLG 900
Query: 1529 EFSQSVINVERSI 1541
+ + E S+
Sbjct: 901 QLERRSRAAEESL 913
>Hs22056881 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 495
Score = 55.1 bits (131), Expect = 1e-06
Identities = 64/279 (22%), Positives = 115/279 (40%), Gaps = 42/279 (15%)
Query: 1215 TSPLLPQSPSLFERYPRPKKKLKQLHWEKID------NAGDSIWKNAQAEKVADD----- 1263
+S P+ P++ P +K L+W +I NA ++W + + + D
Sbjct: 234 SSSQCPRKPAI-----EPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDIRDPSEFEY 288
Query: 1264 LFERGVLSQLEKAFAARETKSLKGKSKEANEKITFLSRDVSQQFGINLHMFSNLDVKDVV 1323
LF + Q +K + ET K K K+ I L SQ GI + +L++KD+
Sbjct: 289 LFSKDTTQQKKKPLS--ETYEKKNKVKKI---IKLLDGKRSQTVGILISSL-HLEMKDIQ 342
Query: 1324 GKVMKCDREFLSTPSVIEFLSKPTIIEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPN 1383
+ D + ++ + + +Y Y T E + D PE+ +
Sbjct: 343 QAIFNVDDSVVDLETLAALYENRAQEDELVKIRKY---YETSKEEELKLLDK--PEQFLH 397
Query: 1384 ELQRADQLYVEFMINLQPYWGSRMRAITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESL 1443
EL + P + R + I + + + + L K+ I RA + + +S+
Sbjct: 398 ELAQI------------PNFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSV 445
Query: 1444 RHVFDVILAVGNYMNDSSK---QAQGFKLSTLQRLTFIK 1479
+ + +ILA GNYMN ++ QA G+ L L +L +K
Sbjct: 446 KDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVK 484
>At2g43800 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 894
Score = 54.3 bits (129), Expect = 2e-06
Identities = 85/421 (20%), Positives = 175/421 (41%), Gaps = 63/421 (14%)
Query: 1233 KKKLKQLHWEKIDNAGDSIWKNAQAEKVADDLFERGVLSQLEKAFAARE--TKSLKGKSK 1290
K KLK LHW+K+ + + Q + + + E +E F + +++ G +
Sbjct: 445 KPKLKTLHWDKVRASSSRVMVWDQIKSNSFQVNE----EMIETLFKVNDPTSRTRDGVVQ 500
Query: 1291 EANEKITFLSRDVSQQFGINLHMFSNLDVKDVVGKVMKCDREFLSTPSVIEFLSK--PTI 1348
+++ FL S I L N+ +V +++ + + L P ++E L K PT
Sbjct: 501 SVSQENRFLDPRKSHNIAILLRAL-NVTADEVCEALIEGNSDTLG-PELLECLLKMAPTK 558
Query: 1349 IEVTNNLARYFNPYSTDWEGVTSVDDAKPPEKDPNELQRADQLYVEFMINLQPYWGSRMR 1408
E + + DD P + P E +++ ++N+ P+ R+
Sbjct: 559 EE------------EDKLKELKDDDDGSPSKIGPAE------KFLKALLNI-PFAFKRID 599
Query: 1409 AITMITTYEKDYSDLVTKLRKIDRAVQCIEQSESLRHVFDVILAVGNYMNDSSKQ--AQG 1466
A+ I +E + L ++ A ++ + + + +L GN MN + + A
Sbjct: 600 AMLYIVKFESEIEYLNRSFDTLEAATGELKNTRMFLKLLEAVLKTGNRMNIGTNRGDAHA 659
Query: 1467 FKLSTLQRLTFIKDEKNSMTFLNY-VEKIIR----------------ENYPEYSHFVEEL 1509
FKL TL +L IK T L++ V++II+ +N E S F ++L
Sbjct: 660 FKLDTLLKLVDIKGADGKTTLLHFVVQEIIKFEGARVPFTPSQSHIGDNMAEQSAFQDDL 719
Query: 1510 EPIFSVTKISIEQLVTDCKEFSQSVINVERSIEIGNLSDPSKFHPLDRVLNKVVPVLPEA 1569
E + K+ ++ + S +INV+++ + + S ++ + R + KV V+ E
Sbjct: 720 E----LKKLGLQVV----SGLSSQLINVKKAAAMDSNSLINETAEIARGIAKVKEVITEL 771
Query: 1570 RKKADLLSDEIKLSLLEFENLMKKFGEDANDKFSKNSFFQKFADFITEF--KKAKTHNVK 1627
+++ ++ L + + K ++ + S K +TE+ ++TH +
Sbjct: 772 KQETG-----VERFLESMNSFLNKGEKEITELQSHGDNVMKMVKEVTEYFHGNSETHPFR 826
Query: 1628 L 1628
+
Sbjct: 827 I 827
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.311 0.128 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,630,200
Number of Sequences: 60738
Number of extensions: 3867036
Number of successful extensions: 12110
Number of sequences better than 1.0e-05: 31
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 12008
Number of HSP's gapped (non-prelim): 77
length of query: 1842
length of database: 30,389,216
effective HSP length: 121
effective length of query: 1721
effective length of database: 23,039,918
effective search space: 39651698878
effective search space used: 39651698878
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)