ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0699 good L KOG1798 Replication, recombination and repair DNA polymerase epsilon, catalytic subunit A
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0699 229274 235828 2185
(2185 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL262w [L] KOG1798 DNA polymerase epsilon catalytic subunit A 2932 0.0
SPBC25H2.13c [L] KOG1798 DNA polymerase epsilon catalytic subunit A 1890 0.0
Hs5453926 [L] KOG1798 DNA polymerase epsilon catalytic subunit A 1654 0.0
At2g27120 [L] KOG1798 DNA polymerase epsilon catalytic subunit A 1421 0.0
At1g08260 [L] KOG1798 DNA polymerase epsilon catalytic subunit A 1366 0.0
CE17767 [L] KOG1798 DNA polymerase epsilon catalytic subunit A 1296 0.0
ECU10g1210 [L] KOG1798 DNA polymerase epsilon catalytic subunit A 848 0.0
>YNL262w [L] KOG1798 DNA polymerase epsilon catalytic subunit A
Length = 2222
Score = 2932 bits (7602), Expect = 0.0
Identities = 1418/2211 (64%), Positives = 1749/2211 (78%), Gaps = 35/2211 (1%)
Query: 6 GSTTAKFVGRGNEYPTQANSFAQVAQQLLNSKKVDEIDEMMGFPRFIPSP--ALSDSK-- 61
GS+TA++ GN+Y T +N++A AQQLLN+ K+D+ID MMGF R++P D+K
Sbjct: 11 GSSTARY-SAGNKYNTLSNNYALSAQQLLNASKIDDIDSMMGFERYVPPQYNGRFDAKDI 69
Query: 62 ------VGWLSNMHPTIISQEMLEEEGN--------LHSATVSGISGVDFYFIDEEGGSF 107
VGWL+NMH T++SQE L N T GISGVDFYF+DEEGGSF
Sbjct: 70 DQIPGRVGWLTNMHATLVSQETLSSGSNGGGNSNDGERVTTNQGISGVDFYFLDEEGGSF 129
Query: 108 KTTVTYDPYFFVSCTDETRIHDIEEYLKKTLEQCIKKVELVLKDDLAMNNHLVGLKKHLI 167
K+TV YDPYFF++C DE+R++D+EE +KK LE C+K ++++ K+DL M+NHL+GL+K LI
Sbjct: 130 KSTVVYDPYFFIACNDESRVNDVEELVKKYLESCLKSLQIIRKEDLTMDNHLLGLQKTLI 189
Query: 168 KLSFSNSNQLFEARRILRPILKINEDENGKKDIYNTGSDYSTR-DVKTLIEDIREYDVPY 226
KLSF NSNQLFEAR++LRPIL+ N + N +++IYN ++ S + D K LIEDIREYDVPY
Sbjct: 190 KLSFVNSNQLFEARKLLRPILQDNANNNVQRNIYNVAANGSEKVDAKHLIEDIREYDVPY 249
Query: 227 HVRVSIDKNIRVGKWYAVSAQGLVELEEKVTFADPVVLAFDIETTKAPLKFPDSAIDQIM 286
HVRVSIDK+IRVGKWY V+ QG +E K+ FADPVV+AFDIETTK PLKFPDSA+DQIM
Sbjct: 250 HVRVSIDKDIRVGKWYKVTQQGFIEDTRKIAFADPVVMAFDIETTKPPLKFPDSAVDQIM 309
Query: 287 MISYMIDGEGFLITNREIISEDIEDFEYTPKDEYKGQFAIFNEPDEMALLQRFFEHIRDV 346
MISYMIDGEGFLITNREIISEDIEDFEYTPK EY G F IFNE DE+ALLQRFFEHIRDV
Sbjct: 310 MISYMIDGEGFLITNREIISEDIEDFEYTPKPEYPGFFTIFNENDEVALLQRFFEHIRDV 369
Query: 347 RPTVISTFNGDFFDWPFVENRAKFHGLNMFDEIGFAPDSEGEYKSSYCTHMDCFRWVKRD 406
RPTVISTFNGDFFDWPF+ NR+K HGL+MFDEIGFAPD+EGEYKSSYC+HMDCFRWVKRD
Sbjct: 370 RPTVISTFNGDFFDWPFIHNRSKIHGLDMFDEIGFAPDAEGEYKSSYCSHMDCFRWVKRD 429
Query: 407 SYLPQGSQGLKAVTQAKLGYNPLELDPELMTPYAYEKPQILSEYSVSDAVATYYLYMKYV 466
SYLPQGSQGLKAVTQ+KLGYNP+ELDPELMTPYA+EKPQ LSEYSVSDAVATYYLYMKYV
Sbjct: 430 SYLPQGSQGLKAVTQSKLGYNPIELDPELMTPYAFEKPQHLSEYSVSDAVATYYLYMKYV 489
Query: 467 HPFIFSLCTIIPLNPDEVLRKGTGTLCEMLLMVQAYQNSVLLPNKHTDPIERFYDGHLLE 526
HPFIFSLCTIIPLNPDE LRKGTGTLCEMLLMVQAYQ+++LLPNKHTDPIERFYDGHLLE
Sbjct: 490 HPFIFSLCTIIPLNPDETLRKGTGTLCEMLLMVQAYQHNILLPNKHTDPIERFYDGHLLE 549
Query: 527 SETYVGGHVESLEAGVFRSDLKNDFKIDPTVIDILLEDLPYALKFCIEVENNGNMEDVTN 586
SETYVGGHVESLEAGVFRSDLKN+FKIDP+ ID LL++LP ALKF +EVEN +++ VTN
Sbjct: 550 SETYVGGHVESLEAGVFRSDLKNEFKIDPSAIDELLQELPEALKFSVEVENKSSVDKVTN 609
Query: 587 FEEIKQQITAQLTDLKINNKRNELPLIYHVDVASMYPNIMTTNRLQPDSMKDEKDCASCD 646
FEEIK QIT +L +LK NN RNELPLIYHVDVASMYPNIMTTNRLQPDS+K E+DCASCD
Sbjct: 610 FEEIKNQITQKLLELKENNIRNELPLIYHVDVASMYPNIMTTNRLQPDSIKAERDCASCD 669
Query: 647 FNRPGKSCDRRLKWAWRGEFFPAKMDEYGMVKRALQNELFPNKNPKSKKQFLTFEELSYS 706
FNRPGK+C R+LKWAWRGEFFP+KMDEY M+KRALQNE FPNKN SKK+ LTF+ELSY+
Sbjct: 670 FNRPGKTCARKLKWAWRGEFFPSKMDEYNMIKRALQNETFPNKNKFSKKKVLTFDELSYA 729
Query: 707 DQVSHIKKRLTDYSRKVYHRVKVTETVEREAIVCQRENPFYVNTVRSFRDRRYEFKGLAK 766
DQV HIKKRLT+YSRKVYHRVKV+E VEREAIVCQRENPFYV+TV+SFRDRRYEFKGLAK
Sbjct: 730 DQVIHIKKRLTEYSRKVYHRVKVSEIVEREAIVCQRENPFYVDTVKSFRDRRYEFKGLAK 789
Query: 767 LWKGKLSKIKPDDVHSKDEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGI 826
WKG LSKI P D H++DEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGI
Sbjct: 790 TWKGNLSKIDPSDKHARDEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGI 849
Query: 827 TCLTGANIIQMARSVVERIGRPLELDTDGIWCILPKSFPENFEIKLRNGKKLFLSYPCSM 886
TCLTGA IIQMAR++VER+GRPLELDTDGIWCILPKSFPE + L NGKKL+LSYPCSM
Sbjct: 850 TCLTGATIIQMARALVERVGRPLELDTDGIWCILPKSFPETYFFTLENGKKLYLSYPCSM 909
Query: 887 LNYKVHQKYTNHQYQDLVDPMKFKYQTKSDNSIFFEVDGPYKAMILPTSKEEGKGIKKRY 946
LNY+VHQK+TNHQYQ+L DP+ + Y+T S+N+IFFEVDGPYKAMILP+SKEEGKGIKKRY
Sbjct: 910 LNYRVHQKFTNHQYQELKDPLNYIYETHSENTIFFEVDGPYKAMILPSSKEEGKGIKKRY 969
Query: 947 AVFNEDGSLAELKGFELKRRGELQLIKNFQSDIFKLFLEGTTLESCYAAVATVANRWLDV 1006
AVFNEDGSLAELKGFELKRRGELQLIKNFQSDIFK+FLEG TLE CY+AVA+V NRWLDV
Sbjct: 970 AVFNEDGSLAELKGFELKRRGELQLIKNFQSDIFKVFLEGDTLEGCYSAVASVCNRWLDV 1029
Query: 1007 LDSKGAMLETEDLIELICENKSMSKTLKEYQGQKSTSITTARRLGEFLGEAMVKDAGLQC 1066
LDS G MLE EDL+ LICEN+SMSKTLKEY+GQKSTSITTARRLG+FLGE MVKD GLQC
Sbjct: 1030 LDSHGLMLEDEDLVSLICENRSMSKTLKEYEGQKSTSITTARRLGDFLGEDMVKDKGLQC 1089
Query: 1067 KFIISSKPHNAPVTERAIPVAIFSSDLHVKRTFLRRWLLDSSLNDFDPRAIIDWDYYRER 1126
K+IISSKP NAPVTERAIPVAIFS+D+ +KR+FLRRW LD SL D D R IIDW YYRER
Sbjct: 1090 KYIISSKPFNAPVTERAIPVAIFSADIPIKRSFLRRWTLDPSLEDLDIRTIIDWGYYRER 1149
Query: 1127 LASVVQKIITIPAALQNIKNPVPRVEHPDWLRKKIAVSEDKFKQTSLNRFFKSTKAPP-- 1184
L S +QKIITIPAALQ + NPVPRVEHPDWL++KIA EDKFKQTSL +FF TK P
Sbjct: 1150 LGSAIQKIITIPAALQGVSNPVPRVEHPDWLKRKIATKEDKFKQTSLTKFFSKTKNVPTM 1209
Query: 1185 -EVKDIEDSFD---EHSANKSRIAKVTYKRK-SKRRNGDTAXXXXXXXXXXXXXXXXDDY 1239
++KDIED F+ E K +IA+ T K+ SKR+ +DY
Sbjct: 1210 GKIKDIEDLFEPTVEEDNAKIKIARTTKKKAVSKRKRNQLTNEEDPLVLPSEIPSMDEDY 1269
Query: 1240 VGWLQYQKTKWKIQHIDRKKREKLFGKTSRASDRSALGNLIRKHVESYADKSWEILQCKP 1299
VGWL YQK KWKIQ DRK+R++LFG T+ + +RSALG++IRK ESYA+ +WE+LQ K
Sbjct: 1270 VGWLNYQKIKWKIQARDRKRRDQLFGNTNSSRERSALGSMIRKQAESYANSTWEVLQYKD 1329
Query: 1300 SIDLGVVEIYALIDRKIQLLKVNIPKTVLMNFKTENFPSGGIENCIVEKSNAELPNVKGI 1359
S + GV+E++ I+ K+Q + +IPKT+ M FK++ P I+NC++EKS+A LPN
Sbjct: 1330 SGEPGVLEVFVTINGKVQNITFHIPKTIYMKFKSQTMPLQKIKNCLIEKSSASLPNNPKT 1389
Query: 1360 NNESSSQLFKLTMSEDTYFNEVNKASSVLNNENVLGIYESSISSNERVIMRLGTCIQFSS 1419
+N + QLFK+T+ E + E +S+ N+ENVLG++E +I+ ++R IM LG + F S
Sbjct: 1390 SNPAGGQLFKITLPESVFLEEKENCTSIFNDENVLGVFEGTITPHQRAIMDLGASVTFRS 1449
Query: 1420 EKMGALGKGLQNGFHMKNLHPVEADRYLQRFDLDIAYLLHFVTDIGYEFYFLYKAWEDVV 1479
+ MGALGKG+Q GF MK+L E +RYL F +DI YLLHF T IGYEF+ L+K+W D +
Sbjct: 1450 KAMGALGKGIQQGFEMKDLSMAENERYLSGFSMDIGYLLHFPTSIGYEFFSLFKSWGDTI 1509
Query: 1480 EIFVLKPSTHAQEVSNKAIESLYNEIYEKKFEKLDKYYDLIKINKNVSFNVNDYTELKRL 1539
I VLKPS AQE++ ++ +Y +++EKK K++ Y L+ I ++++F +T++ +L
Sbjct: 1510 TILVLKPSNQAQEINASSLGQIYKQMFEKKKGKIETYSYLVDIKEDINFEFVYFTDISKL 1569
Query: 1540 LKDLSKMLQNIKEEKGSHTMVILQSPYTHRVAKLLQPLNAFPVVEIATAETHLPALNWQG 1599
+ LS+ +KEE+G +++LQSP+ ++ ++ LN P+V+++ E LP LNWQ
Sbjct: 1570 YRRLSQETTKLKEERGLQFLLLLQSPFITKLLGTIRLLNQMPIVKLSLNEVLLPQLNWQP 1629
Query: 1600 QLMRKAVNHILSLGSWISNLITLSKYSNIPICNLKVDNLGYIIDLMYARQLKKNNIVLWW 1659
L++K VNH+LS GSWIS+LI LS+YSNIPICNL++D++ YIID++YAR+LKK NIVLWW
Sbjct: 1630 TLLKKLVNHVLSSGSWISHLIKLSQYSNIPICNLRLDSMDYIIDVLYARKLKKENIVLWW 1689
Query: 1660 NDKSPLPDHGGVERDFDPRKAELMTDLVFPIMNNPDIYDDVIFEISVYNSVVNTVLSSTM 1719
N+K+PLPDHGG++ DFD + +M D FP +NN +YD+V+ ++ V N VNT+L+S +
Sbjct: 1690 NEKAPLPDHGGIQNDFDLNTSWIMNDSEFPKINNSGVYDNVVLDVGVDNLTVNTILTSAL 1749
Query: 1720 LNEAEGTDLAQNSTSKEESFG-------FVEDXXXXXXXXXXXXXXKELWDDALGDNITA 1772
+N+AEG+DL N+ ++ FV D KE WD+AL +N TA
Sbjct: 1750 INDAEGSDLVNNNMGIDDKDAVINSPSEFVHDAFSNDALNVLRGMLKEWWDEALKENSTA 1809
Query: 1773 DSLVHAFIGWVYNPDAKLFDYALRYHIHTLTQKAVLQLINEFKLAGSSLIFADRNKLLIK 1832
D LV++ WV NP+AKLFD LRYH+H LT+KA+LQL+NEF GS++++ADRN++LIK
Sbjct: 1810 DLLVNSLASWVQNPNAKLFDGLLRYHVHNLTKKALLQLVNEFSALGSTIVYADRNQILIK 1869
Query: 1833 TQKRSVENSYAYGQYLMKAIRSKPMFAYLDLKIDRYWDVLIWMDKYNYGGRACLQIEDKE 1892
T K S EN YAY QY+MKA+R+ PMF+YLDL I RYWD+LIWMDK+N+ G AC++IE+KE
Sbjct: 1870 TNKYSPENCYAYSQYMMKAVRTNPMFSYLDLNIKRYWDLLIWMDKFNFSGLACIEIEEKE 1929
Query: 1893 VQSFQAYSHWHIKDFLPAIYQQEFDDWLVVILDSMVKTKEAYHERNASTQRLTQLPKNTL 1952
Q + A S W +K FL IYQ EF+DW+++ILDSM+KTK++Y + N+ TQR TQ+
Sbjct: 1930 NQDYTAVSQWQLKKFLSPIYQPEFEDWMMIILDSMLKTKQSYLKLNSGTQRPTQIVNVKK 1989
Query: 1953 ADSDVDSQTDSLGGFTHNFSKALIKRAEKLYKNQQEYILDPNFGKDYLSPTIPGSHLVVK 2012
D + DS +SL GF+H FSK L+KR +KL+KNQQE+ILDP + DY+ P +PGSHL VK
Sbjct: 1990 QDKE-DSVENSLNGFSHLFSKPLMKRVKKLFKNQQEFILDPQYEADYVIPVLPGSHLNVK 2048
Query: 2013 NPLLELVKYXXXXXXXXXXXXXEGRALRKELLKTFEIREFDRLAEFKDPSTSFVIPSFIC 2072
NPLLELVK E R LRKELLK FE+REF ++AEFKDPS S V+P F+C
Sbjct: 2049 NPLLELVKSLCHVMLLSKSTILEIRTLRKELLKIFELREFAKVAEFKDPSLSLVVPDFLC 2108
Query: 2073 EHCSYISDIDICRESMERVFICQSCNRSLNKNLIEEHVIERLQAQVASFITQDVKCNKCH 2132
E+C +ISDID C+ + E +F C C+++ N+ L++EH+I++L++ + S++ QD++C++CH
Sbjct: 2109 EYCFFISDIDFCKAAPESIFSCVRCHKAFNQVLLQEHLIQKLRSDIESYLIQDLRCSRCH 2168
Query: 2133 KIKEDAMSPYCPCSGKWELAVSKESFMAQLQIFKNLAESFDFRTLKETLND 2183
K+K D MS +CPC+G WE + +ES + +L +FK +A+ + F L + D
Sbjct: 2169 KVKRDYMSAHCPCAGAWEGTLPRESIVQKLNVFKQVAKYYGFDILLSCIAD 2219
>SPBC25H2.13c [L] KOG1798 DNA polymerase epsilon catalytic subunit A
Length = 2199
Score = 1890 bits (4896), Expect = 0.0
Identities = 1017/2200 (46%), Positives = 1392/2200 (63%), Gaps = 106/2200 (4%)
Query: 38 KVDEIDEMMGFPRFIPSPALSDSKVGWLSNMHPTIISQEMLEEEGNLHSATVSGISGVDF 97
K +EID MMGF + + WL N+HPT+I +GN S +S VDF
Sbjct: 50 KKNEIDRMMGFDSYEGG----QPREAWLLNVHPTVIEST----KGN------STLSAVDF 95
Query: 98 YFIDEEGGSFKTTVTYDPYFFVSCTDETRIHDIEEYLKKTLEQCIKKVELVLKDDLAMNN 157
YFI ++G +F+ T+ Y PYF+++ E + +++YLKK IK + K+DL + N
Sbjct: 96 YFIQDDGDTFRCTIPYSPYFYIAAR-EGKEALVDDYLKKKFVGLIKSTTRIFKEDLQLKN 154
Query: 158 HLVGLKKHLIKLSFSNSNQLFEARRILRPILKINEDENGKKDIYNTGSDYSTRDVKTLIE 217
H+VG +K IKL F N N L R+ L +K N + D Y ++ S+ ++ +IE
Sbjct: 155 HIVGYQKLYIKLVFDNLNDLQAVRKSLMSAVKANSSQQDAVDAY---TNLSSENLNGIIE 211
Query: 218 -----------DIREYDVPYHVRVSIDKNIRVGKWYAVSA-QGLVE---LEEKVTFADPV 262
DIREYDVPYH R ID NIRVG+WY VS +G V+ L ++ A+P
Sbjct: 212 NAFEDPLNHVLDIREYDVPYHSRTLIDLNIRVGQWYTVSYHEGHVQISLLASRIERAEPT 271
Query: 263 VLAFDIETTKAPLKFPDSAIDQIMMISYMIDGEGFLITNREIISEDIEDFEYTPKDEYKG 322
++AFDIETTK PLKFPDS+ D+IMMISYMIDG+GFLITNREIIS++IEDF YTP++E++G
Sbjct: 272 IMAFDIETTKLPLKFPDSSFDKIMMISYMIDGQGFLITNREIISQNIEDFHYTPREEFEG 331
Query: 323 QFAIFNEPDEMALLQRFFEHIRDVRPTVISTFNGDFFDWPFVENRAKFHGLNMFDEIGFA 382
F IFNEPDE+ LL RFF+HIR +P+VI T+NGDFFDWPFV+ RA FHGLN+ +E GF
Sbjct: 332 PFIIFNEPDEVGLLHRFFKHIRSAKPSVIVTYNGDFFDWPFVDARAAFHGLNLTEETGFF 391
Query: 383 PDSEGEYKSSYCTHMDCFRWVKRDSYLPQGSQGLKAVTQAKLGYNPLELDPELMTPYAYE 442
D+E EYKSSYC+HMD FRWVKRDSYLPQGSQGLKAVT +KLGYNP+ELDPELMTPYA E
Sbjct: 392 RDAEDEYKSSYCSHMDAFRWVKRDSYLPQGSQGLKAVTVSKLGYNPIELDPELMTPYASE 451
Query: 443 KPQILSEYSVSDAVATYYLYMKYVHPFIFSLCTIIPLNPDEVLRKGTGTLCEMLLMVQAY 502
KPQ+L++YSVSDAVATY+LYMKYVHPFIFSLC IIPLNPDEVLRKGTGTLCE LL V+A
Sbjct: 452 KPQVLAQYSVSDAVATYFLYMKYVHPFIFSLCNIIPLNPDEVLRKGTGTLCETLLTVEAC 511
Query: 503 QNSVLLPNKHTDPIERFYDGHLLESETYVGGHVESLEAGVFRSDLKNDFKIDPTVIDILL 562
+++LPNKH D ++F+DGHLL SETYVGGHVESLE+GVFRSDL +F +DP V + L+
Sbjct: 512 TKNIILPNKHVDASQKFFDGHLLASETYVGGHVESLESGVFRSDLPTNFNMDPKVYEELI 571
Query: 563 EDLPYALKFCIEVENNGNMEDVTNFEEIKQQITAQLTDLKINNKRNELPLIYHVDVASMY 622
L AL F + VENN N++++ N+EE++ I +L+DL+ KR+E P IYH+DVASMY
Sbjct: 572 LQLDKALDFSLTVENNVNVDEIENYEEVRDSILKKLSDLRDRPKRSEKPRIYHLDVASMY 631
Query: 623 PNIMTTNRLQPDSMKDEKDCASCDFNRPGKSCDRRLKWAWRGEFFPAKMDEYGMVKRALQ 682
PNIM TNRLQPDS+KDE CA+CD N P K+CDRR+ WAWRGE++PAK EY M+ ALQ
Sbjct: 632 PNIMITNRLQPDSVKDESFCATCDLNVPNKTCDRRMVWAWRGEYYPAKKGEYHMIYSALQ 691
Query: 683 NELFPNKNPKSKKQFLTFEELSYSDQVSHIKKRLTDYSRKVYHRVKVTETVEREAIVCQR 742
+E FP P S F +F+ELS S+Q + ++KR+ DYSRKVYHR+ +ERE I+CQ+
Sbjct: 692 SERFPGPTPFS--PFRSFQELSPSEQAAMVQKRIADYSRKVYHRLYDNTVIERETIICQK 749
Query: 743 ENPFYVNTVRSFRDRRYEFKGLAKLWKGKLSKIK-PDDVHSKDEAKKMIVLYDSLQLAHK 801
EN FY++TV+SFRDRRY+FKGL K W +L+ IK + +EAKKM+VLYDSLQLAHK
Sbjct: 750 ENSFYIDTVKSFRDRRYDFKGLQKKWVKQLAAIKEKGGLAEIEEAKKMVVLYDSLQLAHK 809
Query: 802 VILNSFYGYVMRKGSRWYSMEMAGITCLTGANIIQMARSVVERIGRPLELDTDGIWCILP 861
VILNSFYGYVMRKGSRWYS+EMAGITCLTGA IIQMAR +VER GRPLELDTDGIWCILP
Sbjct: 810 VILNSFYGYVMRKGSRWYSIEMAGITCLTGATIIQMARQIVERAGRPLELDTDGIWCILP 869
Query: 862 KSFPENFEIKLRNGKKLFLSYPCSMLNYKVHQKYTNHQYQDLVDPMKFKYQTKSDNSIFF 921
+SFPENFE K ++G K+F+SYPC MLN+ VH+K+TNHQY L DP K Y+T S+NSIFF
Sbjct: 870 ESFPENFEFKKKSGGKVFISYPCVMLNHLVHEKFTNHQYSALKDPEKLVYETTSENSIFF 929
Query: 922 EVDGPYKAMILPTSKEEGKGIKKRYAVFNEDGSLAELKGFELKRRGELQLIKNFQSDIFK 981
EVDGPY+AMILP S EEGK +KKRYAVFN DGSLAELKGFE+KRRGEL+LIK+FQS IFK
Sbjct: 930 EVDGPYRAMILPASTEEGKNLKKRYAVFNFDGSLAELKGFEVKRRGELKLIKDFQSQIFK 989
Query: 982 LFLEGTTLESCYAAVATVANRWLDVLDSKGAMLETEDLIELICENKSMSKTLKEYQGQKS 1041
+FL+G +LE CY VA VA+ WL++L +KG+ L ++LIELI EN+SMSK L EY QKS
Sbjct: 990 VFLKGDSLEECYQEVAYVADTWLEILFTKGSNLTDDELIELISENRSMSKALSEYGSQKS 1049
Query: 1042 TSITTARRLGEFLGEAMVKDAGLQCKFIISSKPHNAPVTERAIPVAIFSSDLHVKRTFLR 1101
TSITTARRL +FLG+ M KD GL C+FIIS+ P PV ERA+PVAIF ++ VKR FLR
Sbjct: 1050 TSITTARRLADFLGDQMTKDKGLACRFIISASPKGRPVAERAVPVAIFFAEESVKRHFLR 1109
Query: 1102 RWLLDSSLNDFDPRAIIDWDYYRERLASVVQKIITIPAALQNIKNPVPRVEHPDWLRKKI 1161
WL D+ L D D R IIDWDYY +RL SVVQK+I+IPAALQ I NPV R PDWL+K++
Sbjct: 1110 LWLKDNGLYDVDIRDIIDWDYYLKRLGSVVQKLISIPAALQRISNPVTRFPLPDWLQKRV 1169
Query: 1162 AVSEDKFKQTSLNRFFKSTKAPP------EVKDIEDSFDEHSANKSRIAKVTYKRKSKRR 1215
AV K++Q ++ F P +V DIED +K +A+VT KRK ++
Sbjct: 1170 AVLNSKYQQKKIDSIFSLAPTNPSTINNTKVTDIEDLGSVTHKDKRIVARVT-KRKLLQQ 1228
Query: 1216 NGDTAXXXXXXXXXXXXXXXXDDYVGWLQYQKTKWKIQHIDRKKREKLFGKTSRASDRSA 1275
+G++ D Y WL+Y K KWK Q + +R L G SR
Sbjct: 1229 SGNS---EAPVSFEVKPVSFMDGYSNWLKYAKKKWKYQKQVKLRRRHLIGFQSR-----Q 1280
Query: 1276 LGNLIRKHVESYADKSWEILQCKPSIDLGVVEIYALIDRKIQLLKVNIPKTVLMNFKTEN 1335
N+++ E + W ILQ + + G++ + +I ++ ++ + + + FK E
Sbjct: 1281 FTNVLQSSAEVMFENLWHILQIRETDVPGILHAWVIIRNRLTSIRFIVNRKFFVCFKDET 1340
Query: 1336 FPSGGIENCIVEKSNAELPNVKGINNESSSQLFKLTMSEDTYFNEVNKASSVLNNENVLG 1395
P+ IE C++EKSNA LP + +S +LF L + E +Y E S + + +V G
Sbjct: 1341 LPNVEIEGCLIEKSNAILP-----HGSTSDKLFLLEIPEKSYLTEKVSISMIFAHPSVSG 1395
Query: 1396 IYESSISSNERVIMRLGTCIQFSSEKMGALGKGLQNGFHMKNL-HPVEAD-RYLQRFDLD 1453
IYE+ I ER+I+ +G+ +F++ GALGKG + GF K P + D YL +++
Sbjct: 1396 IYETRIEPIERLILEMGSRKRFNNSVPGALGKGFEFGFESKMFTDPSDNDVSYLDGVEMN 1455
Query: 1454 IAYLLHFVTDIGYEFYF-LYKAWEDVVEIFVLKPSTHAQEVSNKAIESLYNEIYEKKFEK 1512
Y HF I F F L+ VE ++ ++S +I +Y E+ KF+
Sbjct: 1456 YLYAFHF--SISNRFVFSLFMPHLKKVEA-IIYDKLPGSDMSFPSISKIYEEL-RSKFDN 1511
Query: 1513 LDK-----YYDLIKINKNVSFNVNDYTELKRLLKDLSKMLQNIKEEKGSHTMVILQSPYT 1567
L K Y D + NV F+ N+ ++ K + + L K ++++I++S
Sbjct: 1512 LIKESSIEYPDTLSC--NVIFSGNE----RKAYKLIDEKLLQYFSTKTKNSLLIIESSLP 1565
Query: 1568 HRVAKLLQPLNAFPVVEIATAETHLPALNWQGQLMRKAVNHILSLGSWISNLITLSKYSN 1627
H + ++ + P + I E+++ +L+W+ + K + H L++GSW+ + I LS++S+
Sbjct: 1566 HILKANVKQIEELPYIMIPRLESNIQSLSWKQHIATKMIQHFLAIGSWLFHRIQLSRFSD 1625
Query: 1628 IPICNLKVDNLGYIIDLMYARQLKKNNIVLWWNDKSPLPDHGGVERDFDPRKAELMTDLV 1687
IP+CN + D++ Y ID++Y+R+LK++NI+LWWN K P PD GG+E+D + A L
Sbjct: 1626 IPLCNFESDDIQYSIDVVYSRKLKEHNIILWWN-KGPTPDLGGIEKDSILQIASPKDPLE 1684
Query: 1688 FPIMNNPDIYDDVIFEISVYNSVVNTVLSSTMLNEAEGT-DLAQNSTS--------KEES 1738
+NNP Y + +IS+ N + ++L+S ++N+ EG D+A + + EE
Sbjct: 1685 ---VNNPGAYSNACVDISLSNLALCSILNSALINDIEGIGDMAALNDNYMTAINDDLEEK 1741
Query: 1739 FGFVEDXXXXXXXXXXXXXXKELWDDALGDNITADSLVHAFIGWVYNPDAKLFDYALRYH 1798
G ++ K W++A N AD ++ W+ + + L+ L H
Sbjct: 1742 LGIHDNIGLTHSLPVLKALVKTWWNEAASGNNLADLIIQHLARWISSSKSYLYSPLLSSH 1801
Query: 1799 IHTLTQKAVLQLINEFKLAGSSLIFADRNKLLIKTQKRSVENSYAYGQYLMKAIRSKPMF 1858
+ + +K LQL++E K G+ +I A NK+LIKT K V+N+ Y YL+K+I++ P+F
Sbjct: 1802 VEVIMRKTFLQLLSEIKRLGAHIIHASANKILIKTSKLIVQNAVTYSNYLLKSIKTLPLF 1861
Query: 1859 AYLDLKIDRYWDVLIWMDKYNYGGRACLQIEDKEVQSFQAYSHWHIKDFLPAIYQQEFDD 1918
+LDL + YWD L+WMD NYGG+ + Q WHIK LP I Q EF
Sbjct: 1862 HFLDLNVTEYWDYLLWMDSVNYGGKMVAANFSATNEEPQTVVSWHIKSHLPPIIQPEFQS 1921
Query: 1919 WLVVILDSMVKTKEAYHERNASTQRLTQLPKNTLADSDVDSQTDSLGGFTHNFSKALIKR 1978
W+V ++ + K K E++ + ++ N ++D DS+ G L ++
Sbjct: 1922 WIVEFIEEVYKQK---LEKSNTKVGFVRVKNN---NADEDSEIVGSGILKSKLIHPLKRK 1975
Query: 1979 AEKLYKNQQEYILDPNFGKDYLSPTIPGSHLVVKNPLLELVKYXXXXXXXXXXXXXEGRA 2038
++ + QE LD N +D P +PGS L + LELVK E R
Sbjct: 1976 VAQVRRCFQELQLDENTREDLKFPKLPGSFLNYTDGALELVKSICAVFELSHDLNLEVRF 2035
Query: 2039 LRKELLKTFEIREFDRLAEFKDPSTSFVIPSFICEHCSYISDIDIC--------RESMER 2090
L+K LL +I+EF A F+ PS + C+ C D D+C R+ M
Sbjct: 2036 LKKSLLSLLQIQEFSTQAVFRYPSRRLSLDQIPCKQCGVHQDFDLCLHEHLWPTRDDMGT 2095
Query: 2091 V-----FICQSCNRSLNKNLIEEHVIERLQAQVASFITQDVKCNKCHKIKEDAMSPYCPC 2145
+ + C SCN ++ + EE +++ L Q+ + QD+ C+KC +K+ ++ C C
Sbjct: 2096 LVFSDGWSCSSCNLVYDRWVFEETLVDNLYHQLTLYQLQDLICSKCKTVKQWSLKERCSC 2155
Query: 2146 SGKWELAVSKESFMAQLQIFKNLAESFDFRTLKETLNDFL 2185
SG+W L +S F L +++++A+ ++F L+ ++ L
Sbjct: 2156 SGEWVLQLSPTKFREMLNVYQSVADFYEFSILQNSVQSIL 2195
>Hs5453926 [L] KOG1798 DNA polymerase epsilon catalytic subunit A
Length = 2286
Score = 1654 bits (4282), Expect = 0.0
Identities = 952/2299 (41%), Positives = 1334/2299 (57%), Gaps = 189/2299 (8%)
Query: 23 ANSFAQVAQQLLNSKKVDEIDEMMGFPRFIPSPALSDSKVGWLSNMHPTIISQEMLEEEG 82
A S ++L S+ D++D GF R + P K GWL NMHPT E+L+E+
Sbjct: 25 ATSSVSALKRLERSQWTDKMDLRFGFER-LKEPG---EKTGWLINMHPT----EILDEDK 76
Query: 83 NLHSATVSGISGVDFYFIDEEGGSFKTTVTYDPYFFVSCTDETRIHDIEEYLKKTLEQCI 142
L SA VD+YFI ++G FK + Y PYF+++ T + ++ +L K + I
Sbjct: 77 RLGSA-------VDYYFIQDDGSRFKVALPYKPYFYIA-TRKGCEREVSSFLSKKFQGKI 128
Query: 143 KKVELVLKDDLAMNNHLVGLKKHLIKLSFSNSNQLFEARRILRPILKINEDENGKKDIYN 202
KVE V K+DL + NHLVGLK++ I+LSF L + R+ + P +K N +++ D Y
Sbjct: 129 AKVETVPKEDLDLPNHLVGLKRNYIRLSFHTVEDLVKVRKEISPAVKKNREQDHASDAYT 188
Query: 203 -------------TGSDYSTRDVKTLIE---DIREYDVPYHVRVSIDKNIRVGKWYAVSA 246
T + +++ + ++ D+REYDVPYH+R+SID I V WY V
Sbjct: 189 ALLSSVLQRGGVITDEEETSKKIADQLDNIVDMREYDVPYHIRLSIDLKIHVAHWYNVRY 248
Query: 247 QG------LVELEEKVTFADPVVLAFDIETTKAPLKFPDSAIDQIMMISYMIDGEGFLIT 300
+G + ++ V DPVVLAFDIETTK PLKFPD+ DQIMMISYMIDG+G+LIT
Sbjct: 249 RGNAFPVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMIDGQGYLIT 308
Query: 301 NREIISEDIEDFEYTPKDEYKGQFAIFNEPDEMALLQRFFEHIRDVRPTVISTFNGDFFD 360
NREI+SEDIEDFE+TPK EY+G F +FNEPDE L+QR+FEH+++ +PT++ T+NGDFFD
Sbjct: 309 NREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEAHLIQRWFEHVQETKPTIMVTYNGDFFD 368
Query: 361 WPFVENRAKFHGLNMFDEIGFAPDSEGEYKSSYCTHMDCFRWVKRDSYLPQGSQGLKAVT 420
WPFVE RA HGL+M EIGF DS+GEYK+ C HMDC RWVKRDSYLP GS LKA
Sbjct: 369 WPFVEARAAVHGLSMQQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVGSHNLKAAA 428
Query: 421 QAKLGYNPLELDPELMTPYAYEKPQILSEYSVSDAVATYYLYMKYVHPFIFSLCTIIPLN 480
+AKLGY+P+ELDPE M A E+PQ L+ YSVSDAVATYYLYMKYVHPFIF+LCTIIP+
Sbjct: 429 KAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFALCTIIPME 488
Query: 481 PDEVLRKGTGTLCEMLLMVQAYQNSVLLPNKHTDPIERFYD-GHLLESETYVGGHVESLE 539
PDEVLRKG+GTLCE LLMVQA+ +++ PNK + D GH+L+SETYVGGHVE+LE
Sbjct: 489 PDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDSETYVGGHVEALE 548
Query: 540 AGVFRSDLKNDFKIDPTVIDILLEDLPYALKFCIEVENNGNMEDVTNFEEIKQQITAQLT 599
+GVFRSD+ F+++P D LL+ + L+ +E E +E VTNFEE+ +I ++L
Sbjct: 549 SGVFRSDIPCRFRMNPAAFDFLLQRVEKTLRHALEEEEKVPVEQVTNFEEVCDEIKSKLA 608
Query: 600 DLKINNKRNELPLIYHVDVASMYPNIMTTNRLQPDSMKDEKDCASCDFNRPGKSCDRRLK 659
LK R E PLIYH+DV +MYPNI+ TNRLQP +M DE CA+CDFN+PG +C R++
Sbjct: 609 SLKDVPSRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPGANCQRKMA 668
Query: 660 WAWRGEFFPAKMDEYGMVKRALQNELFPNKNPKSKKQFLTFEELSYSDQVSHIKKRLTDY 719
W WRGEF PA EY ++ L++E FP P+ + F ELS +Q + K+RL DY
Sbjct: 669 WQWRGEFMPASRSEYHRIQHQLESEKFPPLFPEGPAR--AFHELSREEQAKYEKRRLADY 726
Query: 720 SRKVYHRVKVTETVEREAIVCQRENPFYVNTVRSFRDRRYEFKGLAKLWKGKLSK-IKPD 778
RK Y ++ +T+ ER +CQREN FYV+TVR+FRDRRYEFKGL K+WK KLS ++
Sbjct: 727 CRKAYKKIHITKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLSAAVEVG 786
Query: 779 DVHSKDEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGITCLTGANIIQMA 838
D K M VLYDSLQLAHK ILNSFYGYVMRKG+RWYSMEMAGI C TGANII A
Sbjct: 787 DAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGANIITQA 846
Query: 839 RSVVERIGRPLELDTDGIWCILPKSFPENFEIKLRNGKK--LFLSYPCSMLNYKVHQKYT 896
R ++E+IGRPLELDTDGIWC+LP SFPENF K N KK + +SYP +MLN V + +T
Sbjct: 847 RELIEQIGRPLELDTDGIWCVLPNSFPENFVFKTTNVKKPKVTISYPGAMLNIMVKEGFT 906
Query: 897 NHQYQDLVDPMKFKYQTKSDNSIFFEVDGPYKAMILPTSKEEGKGIKKRYAVFNEDGSLA 956
N QYQ+L +P Y T+S+NSIFFEVDGPY AMILP SKEEGK +KKRYAVFNEDGSLA
Sbjct: 907 NDQYQELAEPSSLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLA 966
Query: 957 ELKGFELKRRGELQLIKNFQSDIFKLFLEGTTLESCYAAVATVANRWLDVLDSKGAMLET 1016
ELKGFE+KRRGELQLIK FQS +F+ FL+G+TLE Y +VA VA+ WLDVL SK A +
Sbjct: 967 ELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSKAANMPD 1026
Query: 1017 EDLIELICENKSMSKTLKEYQGQKSTSITTARRLGEFLGEAMVKDAGLQCKFIISSKPHN 1076
+L ELI EN+SMS+ L++Y QKSTSI+TA+RL EFLG+ MVKDAGL C++IIS KP
Sbjct: 1027 SELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYIISRKPEG 1086
Query: 1077 APVTERAIPVAIFSSDLHVKRTFLRRWLLDSSLNDFDPRAIIDWDYYRERLASVVQKIIT 1136
+PVTERAIP+AIF ++ V++ FLR+WL SSL DFD RAI+DWDYY ERL S +QKIIT
Sbjct: 1087 SPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRAILDWDYYIERLGSAIQKIIT 1146
Query: 1137 IPAALQNIKNPVPRVEHPDWLRKKIAVSEDKFKQTSLNRFFK------------STKAP- 1183
IPAALQ +KNPVPRV+HPDWL KK+ D +KQ ++ F S +P
Sbjct: 1147 IPAALQQVKNPVPRVKHPDWLHKKLLEKNDVYKQKKISELFTLEGRRQVTMAEASEDSPR 1206
Query: 1184 PEVKDIEDSFDEHSANKSRIAKVTYKRK-----SKRRNGD---TAXXXXXXXXXXXXXXX 1235
P D+ED + + A VT KRK S+ + D T
Sbjct: 1207 PSAPDMEDFGLVKLPHPA--APVTVKRKRVLWESQEESQDLTPTVPWQEILGQPPALGTS 1264
Query: 1236 XDDYVGWLQYQKTKWKIQ---HIDRKKREKLFGKTS-------RASDRSALGNLIRKHVE 1285
++++ WL++ K KW++Q + R+KR++L R + LG+ +R+
Sbjct: 1265 QEEWLVWLRFHKKKWQLQARQRLARRKRQRLESAEGVLRPGAIRDGPATGLGSFLRRTAR 1324
Query: 1286 SYADKSWEILQCKPSIDLGVVEIYALIDRKIQLLKVNIPKTVLMNFKTENFPSGGIENCI 1345
S D W+I+Q + G+ ++AL+ + ++++IP+ +N + G
Sbjct: 1325 SILDLPWQIVQISETSQAGLFRLWALVGSDLHCIRLSIPRVFYVNQRVAKAEEGAS---- 1380
Query: 1346 VEKSNAELPNVKGINNESSSQLFKLTMSEDTYFNEVNKASSVLNNENVLGIYESSISSNE 1405
K N LP + N L++ ++ ED Y +N+ ++ L+ ++ G+YE+ +
Sbjct: 1381 YRKVNRVLPRSNMVYN-----LYEYSVPEDMYQEHINEINAELSAPDIEGVYETQVPLLF 1435
Query: 1406 RVIMRLGTCIQFSSEKMGALGKGLQNGFHMKNLH--PVEADRYLQRFDLDIAYLLHFVTD 1463
R ++ LG + + + L F +++L + YL+ + YL H
Sbjct: 1436 RALVHLGCVCVVNKQLVRHLSGWEAETFALEHLEMRSLAQFSYLEPGSIRHIYLYHHA-Q 1494
Query: 1464 IGYEFYFLYKAWEDVVEIFVLKPSTHAQEVSNKAIESLYNEIYEKKFEKLDKYYDLIKIN 1523
+ ++ + +FVL Q S + +LY+ + EK+ +L+
Sbjct: 1495 AHKALFGIFIPSQRRASVFVLDTVRSNQMPS---LGALYSAEHGLLLEKVGP--ELLPPP 1549
Query: 1524 KNVSFNVNDYTELKRLLKDLSKMLQNIKEEKGSHTMVILQSPYT-HRVAKLLQPLNAFPV 1582
K+ +F V T+LK + + + + L KEE+ T++ +QS + R+A + L FP+
Sbjct: 1550 KH-TFEVRAETDLKTICRAIQRFLLAYKEERRGPTLIAVQSSWELKRLASEIPVLEEFPL 1608
Query: 1583 VEIATAET-HLPALNWQGQLMRKAVNHILSLGSWISNLITLSKYSNIPICNLKVDNLGYI 1641
V I A+ + L+WQ R+ + H L+L + +S +S+Y +IPI NL D +
Sbjct: 1609 VPICVADKINYGVLDWQRHGARRMIRHYLNLDTCLSQAFEMSRYFHIPIGNLPEDISTFG 1668
Query: 1642 IDLMYARQLKKNNIVLWWNDKSPLPDHGGVERDFDPRKAELMTDLVFPIMNNPDIYDDVI 1701
DL +AR L+++N +LW + + PD GG E D + E I N+ Y V
Sbjct: 1669 SDLFFARHLQRHNHLLWLSPTAR-PDLGGKEADDNCLVMEFDDQATVEI-NSSGCYSTVC 1726
Query: 1702 FEISVYNSVVNTVLSSTMLNEAEGTDLAQNSTSKEESFGFVEDXXXXXXXXXXXXXXKEL 1761
E+ + N VNT+L S +N+ EG D S + +ED E
Sbjct: 1727 VELDLQNLAVNTILQSHHVNDMEGADSMGISFDVIQQAS-LEDMITGGQAASAPASYDET 1785
Query: 1762 ----------------WDDALGD--NITADSLVHAFIGWVYNPDAKLFDYALRYHIHTLT 1803
W + NI AD+ V F W+ +P + L D AL +H +
Sbjct: 1786 ALCSNTFRILKSMVVGWVKEITQYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHNMM 1845
Query: 1804 QKAVLQLINEFKLAGSSLIFADRNKLLIKTQKRSVENSYAYGQYLMKAIRSKPMFAYLDL 1863
+K LQLI EFK GSS+I+A+ N++++ T+KR VE++ AY +Y+ +I SK F L +
Sbjct: 1846 KKLFLQLIAEFKRLGSSVIYANFNRIILCTKKRRVEDAIAYVEYITSSIHSKETFHSLTI 1905
Query: 1864 KIDRYWDVLIWMDKYNYG---GRACLQI-----------------------------EDK 1891
R W+ L+WMD NYG G+ +I E++
Sbjct: 1906 SFSRCWEFLLWMDPSNYGGIKGKVSSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEE 1965
Query: 1892 EVQSFQAY----SHWHIKDFLPAIYQQEFDDWLVVILDSMVKTKEAYHERNASTQRLT-- 1945
E + ++W+I FLP + ++ ++I+ + + YH +R
Sbjct: 1966 EAEESNVEDLLENNWNILQFLPQAASCQ--NYFLMIVSAYIVA--VYHCMKDGLRRSAPG 2021
Query: 1946 QLPKNTLADSDVDSQTDSLGG----------------FTHNFSKALIKRAEKLYKNQQEY 1989
P S + + + G T +F K +K+ ++
Sbjct: 2022 STPVRRRGASQLSQEAEGAVGALPGMITFSQDYVANELTQSFFTITQKIQKKVTGSRNST 2081
Query: 1990 ILDPNFGKDYLSPTIPGSHLVVKNPLLELVKYXXXXXXXXXXXXXEGRALRKELLKTFEI 2049
L F P +PGSHL++ NP LE +KY + L ++LL+ ++
Sbjct: 2082 ELSEMF------PVLPGSHLLLNNPALEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDV 2135
Query: 2050 REFDRLAEFKDPSTSFVIPSFICEHCSYISDIDICRES-------MERVFICQSCNRSLN 2102
EF A+F+DP S+V+P IC C++ D+D+C++S + ++C +C +
Sbjct: 2136 GEFSEEAQFRDPCRSYVLPEVICRSCNFCRDLDLCKDSSFSEDGAVLPQWLCSNCQAPYD 2195
Query: 2103 KNLIEEHVIERLQAQVASFITQDVKCNKCHKIKEDAMSPYCPCSGKWELAVSKESFMAQL 2162
+ IE ++E LQ ++ +F QD+ C KC +KE +M YC C+G + L + + FM Q+
Sbjct: 2196 SSAIEMTLVEVLQKKLMAFTLQDLVCLKCRGVKETSMPVYCTCAGDFALTIHTQVFMEQI 2255
Query: 2163 QIFKNLAESFDFRTLKETL 2181
IF+N+A+ + L ETL
Sbjct: 2256 GIFRNIAQHYGMSYLLETL 2274
>At2g27120 [L] KOG1798 DNA polymerase epsilon catalytic subunit A
Length = 2154
Score = 1421 bits (3679), Expect = 0.0
Identities = 847/2209 (38%), Positives = 1254/2209 (56%), Gaps = 132/2209 (5%)
Query: 34 LNSKKV---DEIDEMMGFPRFIPSPALSDSKVGWLSNMHPTIISQEMLEEEGNLHSATVS 90
LN +KV DE++ +GF F + ++++GWL T S + + T
Sbjct: 10 LNVQKVSAADELETKLGFGLF----SQGETRLGWLL----TFASSSWEDAD------TGK 55
Query: 91 GISGVDFYFIDEEGGSFKTTVTYDPYFFVSCTDETRIHDIEEYLKKTLEQCIKKVELVLK 150
S VD +F+ ++G SFKT + PY + + D + ++E YL++ E+ + +++V K
Sbjct: 56 TFSCVDLFFVTQDGSSFKTKYKFRPYLYAATKDNMEL-EVEAYLRRRYERQVADIQIVHK 114
Query: 151 DDLAMNNHLVGLKKHLIKLSFSNSNQLFEARRILRPILKINEDENGKKDIYNT----GSD 206
+DL + NHL GL+K +K+SF QL E +R L I++ N + + Y + +
Sbjct: 115 EDLYLKNHLSGLQKKYLKVSFDTVQQLVEVKRDLLHIVERNLAKFNALEAYESILSGKRE 174
Query: 207 YSTRDVKTLIEDIREYDVPYHVRVSIDKNIRVGKWYAVSAQGLVELEEKVTF----ADPV 262
+D + D+REYDVPYHVR +ID ++R G+WY VS + EK T A+
Sbjct: 175 QRPQDCLDSVVDLREYDVPYHVRFAIDNDVRSGQWYNVSISSTDVILEKRTDLLQRAEVR 234
Query: 263 VLAFDIETTKAPLKFPDSAIDQIMMISYMIDGEGFLITNREIISEDIEDFEYTPKDEYKG 322
V AFDIET K PLKFPD+ DQIMMISYM+DG+GFLITNRE + +DIED EYTPK E++G
Sbjct: 235 VCAFDIETVKLPLKFPDAEYDQIMMISYMVDGQGFLITNRECVGKDIEDLEYTPKPEFEG 294
Query: 323 QFAIFNEPDEMALLQRFFEHIRDVRPTVISTFNGDFFDWPFVENRAKFHGLNMFDEIGFA 382
F + N +E+ LL+++F H+++++P + T+NGDFFDWPF+E RA HG+ M +E+GF
Sbjct: 295 YFKVTNVTNEVELLRKWFSHMQELKPGIYVTYNGDFFDWPFIERRASHHGIKMNEELGFR 354
Query: 383 PD-SEGEYKSSYCTHMDCFRWVKRDSYLPQGSQGLKAVTQAKLGYNPLELDPELMTPYAY 441
D ++GE ++ + H+DCF WVKRDSYLPQGSQGLKAVT+ KLGY+PLE++PE M +A
Sbjct: 355 CDQNQGECRAKFVCHLDCFSWVKRDSYLPQGSQGLKAVTKVKLGYDPLEVNPEDMVRFAM 414
Query: 442 EKPQILSEYSVSDAVATYYLYMKYVHPFIFSLCTIIPLNPDEVLRKGTGTLCEMLLMVQA 501
EKPQ ++ YSVSDAVATYYLYM YVHPF+FSL TIIP+ PDEVLRKG+GTLCEMLLMV+A
Sbjct: 415 EKPQTMASYSVSDAVATYYLYMTYVHPFVFSLATIIPMVPDEVLRKGSGTLCEMLLMVEA 474
Query: 502 YQNSVLLPNKHTDPIERFYDGHLLESETYVGGHVESLEAGVFRSDLKNDFKIDPTVIDIL 561
Y+ +V+ PNK+ E+FY G LLESETY+GGHVE L++GVFRSD+ FK+D + L
Sbjct: 475 YKANVVCPNKNQADPEKFYQGKLLESETYIGGHVECLQSGVFRSDIPTSFKLDASAYQQL 534
Query: 562 LEDLPYALKFCIEVENNGNMEDVTNFEEIKQQITAQLTDLKINNKRNELPLIYHVDVASM 621
+++L L++ I VE M+ V+NF+E+K+ I +L L+ + R E PLIYH+DVA+M
Sbjct: 535 IDNLGRDLEYAITVEGKMRMDSVSNFDEVKEVIREKLEKLRDDPIREEGPLIYHLDVAAM 594
Query: 622 YPNIMTTNRLQPDSMKDEKDCASCDFNRPGKSCDRRLKWAWRGEFFPAKMDEYGMVKRAL 681
YPNI+ TNRLQP S+ ++ C +CDFN P K+C R+L+W WRG F EY +K+ +
Sbjct: 595 YPNIILTNRLQPPSIVTDEVCTACDFNGPEKTCLRKLEWVWRGVTFKGNKSEYYHLKKQI 654
Query: 682 QNE-LFPNKNPKSKKQFLTFEELSYSDQVSHIKKRLTDYSRKVYHRVKVTETVE-REAIV 739
++E + N +S K FL +L +Q S +K+RL Y +K Y RV E REA +
Sbjct: 655 ESESVDAGANMQSSKPFL---DLPKVEQQSKLKERLKKYCQKAYSRVLDKPITEVREAGI 711
Query: 740 CQRENPFYVNTVRSFRDRRYEFKGLAKLWKGKLSKIKPDDVHSK-DEAKKMIVLYDSLQL 798
C RENPFYV+TVRSFRDRRYE+K L K+WKGKLS+ K K EA M+V+YDSLQL
Sbjct: 712 CMRENPFYVDTVRSFRDRRYEYKTLNKVWKGKLSEAKASGNLIKIQEAHDMVVVYDSLQL 771
Query: 799 AHKVILNSFYGYVMRKGSRWYSMEMAGITCLTGANIIQMARSVVERIGRPLELDTDGIWC 858
AHK ILNSFYGYVMRKG+RWYSMEMAG+ TGA IIQ AR ++ERIG+PLELDTDGIWC
Sbjct: 772 AHKCILNSFYGYVMRKGARWYSMEMAGVVTYTGAKIIQNARLLIERIGKPLELDTDGIWC 831
Query: 859 ILPKSFPENFEIKLRNGKKLFLSYPCSMLNYKVHQKYTNHQYQDLVDPMKFKYQTKSDNS 918
LP SFPENF K + KK +SYPC +LN V + +N QYQ LVDP++ Y ++S+ S
Sbjct: 832 ALPGSFPENFTFKTIDMKKFTISYPCVILNVDVAKNNSNDQYQTLVDPVRKTYNSRSECS 891
Query: 919 IFFEVDGPYKAMILPTSKEEGKGIKKRYAVFNEDGSLAELKGFELKRRGELQLIKNFQSD 978
I FEVDGPYKAMI+P SKEEG IKKRYAVFN DG++AELKGFE+KRRGEL+LIK FQ++
Sbjct: 892 IEFEVDGPYKAMIIPASKEEGILIKKRYAVFNHDGTIAELKGFEMKRRGELKLIKVFQAE 951
Query: 979 IFKLFLEGTTLESCYAAVATVANRWLDVLDSKGAMLETEDLIELICENKSMSKTLKEYQG 1038
+F FL G+TLE CY+AVA VANRWLD+L+ +G + +L++ I E+ +MSK+L +Y
Sbjct: 952 LFDKFLHGSTLEECYSAVAAVANRWLDLLEGQGKDIADSELLDYISESSTMSKSLADYGQ 1011
Query: 1039 QKSTSITTARRLGEFLGEAMVKDAGLQCKFIISSKPHNAPVTERAIPVAIFSSDLHVKRT 1098
QKS ++TTA+RL +FLG+ MVKD GL+C++I++ +P PV+ERA+PVAIF +D K+
Sbjct: 1012 QKSCAVTTAKRLADFLGDTMVKDKGLRCQYIVAREPEGTPVSERAVPVAIFQTDDPEKKF 1071
Query: 1099 FLRRWLLDSSLNDFDPRAIIDWDYYRERLASVVQKIITIPAALQNIKNPVPRVEHPDWLR 1158
+L++W SS R+IIDW YY++RL S +QK+ITIPAA+Q + NPV RV HP WL
Sbjct: 1072 YLQKWCKISSYTGI--RSIIDWMYYKQRLHSAIQKVITIPAAMQKVANPVLRVRHPYWLE 1129
Query: 1159 KKIAVSEDKFKQTSLNRFFK------STKAPPEVKDIEDSFDEHSANKSRIAKVTYKRKS 1212
KK+ DKF+Q + F ST V DIE+ E+ + V +
Sbjct: 1130 KKVC---DKFRQGKIVDMFSSANKDHSTTQDNVVADIEEFCKENRPSVKGPKPVARSFEV 1186
Query: 1213 KRRNGD----TAXXXXXXXXXXXXXXXXDDYVGWLQYQKTKWKIQHIDRKKR-------- 1260
R + + + DY GWL+ +K KWK+ ++KKR
Sbjct: 1187 DRNHSEGKQQESWDPEFHDISLQNVDKNVDYQGWLELEKRKWKMTLTNKKKRRFDDLKPC 1246
Query: 1261 -----EKLFGKTSRASDRSALGNLIRKHVESYADKSWEILQCKPSIDLGVVEIYALIDRK 1315
K+ K + R +G+ R+ E+ +I+Q S G + +++
Sbjct: 1247 NQIDAHKINKKVCKG--RVGVGSYFRRPEEALTSSYLQIIQLVQSPQSGQFFAWVVVEGL 1304
Query: 1316 IQLLKVNIPKTVLMNFKTE---NFPSGGIENCIVEKSNAELPNVKGINNESSSQLFKLTM 1372
+ + + IP+ +N K NF +G N I+ ++ + ++ L + +
Sbjct: 1305 MLKIPLTIPRVFYINSKASIAGNF-TGKCINKILPHGKPCYNLMEARHLHNTHILLLVNI 1363
Query: 1373 SEDTYFNEVNKASSVLNNENVLGIYESSISSNERVIMRLGTCIQFSSEKMGALGKGLQNG 1432
ED + E K +++L + + GIYE+ + I ++G + A + Q+G
Sbjct: 1364 QEDQFIKESKKLAALLADPEIEGIYETKMPLEFSAICQIGCVCKIEDT---AKHRNTQDG 1420
Query: 1433 FHMKNLHPVEAD--RYLQRFDLDIAYLLHFVTDIGYEFYFLYKAWEDVVEIFVLKPSTHA 1490
+ + LH + RYL+ + + YL H T G Y LY ++ + V+ P
Sbjct: 1421 WKLGELHRITTTECRYLEN-SIPLVYLYH-STSTGRAVYVLYCHASKLMSVVVVNPYGD- 1477
Query: 1491 QEVSNKAIESLYNEIYEKKFEKLDKYYDLIKINKNVSFNVNDYTELKRLLKDLSKMLQNI 1550
+E+ + A+E + + ++ + + + F V + K L K L
Sbjct: 1478 KELLSSALERQFRDRCQELSPEPFSW-------DGILFQVEYVDHPEAATKFLQKALCEY 1530
Query: 1551 KEEKGSHTMVILQSPYTHRVAKLLQPLNAFPVVEIA--TAETHLPALNWQGQLMRKAVNH 1608
+EE T+ +++ P + + ++ L FP V I + ++WQ + AV
Sbjct: 1531 REENCGATVAVIECPDFNTTKEGVKALEDFPCVRIPFNDDDNSYQPVSWQRPAAKIAVLR 1590
Query: 1609 ILSLGSWISNLITLSKYSNIPICNLKVDNLGYIIDLMYARQLKKNNIVLWWNDKSPLPDH 1668
S W+ I S+Y+++P+ N D L + +D+ +R L+ VLW +D +PD
Sbjct: 1591 CASAIQWLDRRIAQSRYAHVPLGNFGRDWLTFTVDIFLSRALRDQQQVLWVSDNG-VPDL 1649
Query: 1669 GGVERDFDPRKAELM-TDLVFPIMNNPDIYDDVIFEISVYNSVVNTVLSSTMLNEAEGTD 1727
G + + EL T L+F P Y V E+ V+ VN +L S +++E EG
Sbjct: 1650 GDINNEETFLADELQETSLLF-----PGAYRKVSVELKVHRLAVNALLKSDLVSEMEGGG 1704
Query: 1728 -LAQNS--TSKEESFGFVEDXXXXXXXXXXXXXXKELWDDALGD-NITADSLVHAFIGWV 1783
L NS +S ++ F E+ K L DA NI ADS++ W+
Sbjct: 1705 FLGVNSRGSSLNDNGSFDENNGCAQAFRVLKQLIKRLLHDACNSGNIYADSILQHLSWWL 1764
Query: 1784 YNPDAKLFDYALRYHIHTLTQKAVLQLINEFKLAGSSLIFADRNKLLIKTQKRSVENSYA 1843
+P +KL D AL +H + QK L+ + + G+ +I+AD +K++I T K + +
Sbjct: 1765 RSPSSKLHDPALHLMLHKVMQKVFALLLTDLRRLGAIIIYADFSKVIIDTGKFDLSAAKT 1824
Query: 1844 YGQYLMKAIRSKPMFAYLDLKIDRYWDVLIWMDKYNYGGRACL--QIEDKEVQSFQAYSH 1901
Y + L+ + S+ +F + L+ YW L++MD++NY G +I EV
Sbjct: 1825 YCESLLTVMGSRDIFKLILLEPVHYWHSLLFMDQHNYAGIRATGDEISGNEV---TIEPK 1881
Query: 1902 WHIKDFLPAIYQQEFDDWLVVILDSMV--KTKEAYHERNASTQRLTQLPKNTLADSDVDS 1959
W + LP Q++F ++I+ + + K A ++ S + L
Sbjct: 1882 WSVARHLPEYIQKDF----IIIVATFIFGPWKFALEKKRGSAESL--------------- 1922
Query: 1960 QTDSLGGFTHNFSKALIKRAEKLYKNQQEYILDPNFG-KDYLSPTIPGSHLVVKNPLLEL 2018
+ + + I + N + +I D N + S P E
Sbjct: 1923 EAEMVEYLKEQIGTRFISMIVEKIGNIRSHIKDINVSDASWASGQAPKGDYT-----FEF 1977
Query: 2019 VKYXXXXXXXXXXXXXEGRALRKELLKTFEIREFDRLAEFKDPSTSFVIPSFICEHCSYI 2078
++ + +RK LLK +++E AEF DP SF++P+ C +C
Sbjct: 1978 IQIITAVLALDQNVQQDVLVMRKILLKYIKVKECAAEAEFIDPGPSFILPNVACSNCGAY 2037
Query: 2079 SDIDICRES---MERVFIC--QSCNRSLNKNLIEEHVIERLQAQVASFITQDVKCNKCHK 2133
D+D CR+S E+ + C C + +K IE +I+ ++ + + QD+ CN+C++
Sbjct: 2038 RDLDFCRDSALLTEKEWSCADPQCVKIYDKEQIESSIIQMVRQRERMYQLQDLVCNRCNQ 2097
Query: 2134 IKEDAMSPYCPCSGKWELAVSKESFMAQLQIFKNLAESFDFRTLKETLN 2182
+K ++ C CSG + S F +++IF ++A+ FR L+E ++
Sbjct: 2098 VKAAHLTEQCECSGSFRCKESGSDFHKRIEIFLDIAKRQKFRLLEECIS 2146
>At1g08260 [L] KOG1798 DNA polymerase epsilon catalytic subunit A
Length = 2271
Score = 1366 bits (3535), Expect = 0.0
Identities = 858/2319 (36%), Positives = 1269/2319 (53%), Gaps = 258/2319 (11%)
Query: 40 DEIDEMMGFPRFIPSPALSDSKVGWLSNMHPTIISQEMLEEEGNLHSATVSGISGVDFYF 99
DE++ +GF F + ++++GWL + + G ++S VD YF
Sbjct: 27 DELESKLGFGLF----SEGETRLGWLLTFSSSSWEDR---DTGKVYSC-------VDLYF 72
Query: 100 IDEEGGSFKTTVTYDPYFFVSCTDETRIHDIEEYLKKTLEQCIKKVELVLKDDLAMNNHL 159
+ ++G SFKT + PYF+ + D+ + ++E YL++ E+ + +E+V K+DL + NHL
Sbjct: 73 VTQDGFSFKTKYKFRPYFYAATKDKMEL-ELEAYLRRRYERQVADIEIVEKEDLDLKNHL 131
Query: 160 VGLKKHLIKLSFSNSNQLFEARRILRPILKINEDENGKKDIYNT----GSDYSTRDVKTL 215
GL+K +K+SF QL E +R L I++ N+ + + Y + + +D
Sbjct: 132 SGLQKKYLKISFDTVQQLMEVKRDLLHIVERNQAKFDALEAYESILAGKREQRPQDCLDS 191
Query: 216 IEDIREYDVPYHVRVSIDKNIRVGKWYAVSAQGLVELEEKVTF----ADPVVLAFDIETT 271
I D+REYDVPYHVR +ID ++R G+WY VS + EK T A+ V AFDIETT
Sbjct: 192 IVDLREYDVPYHVRFAIDNDVRSGQWYNVSISSTDVILEKRTDLLQRAEVRVCAFDIETT 251
Query: 272 KAPLKFPDSAIDQIMMISYMIDGEGFLITNREI---ISEDIEDFEYTPKDEYKGQFAIFN 328
K PLKFPD+ DQIMMISYM+DG+GFLI NRE+ + ED+ED EYTPK E++G F + N
Sbjct: 252 KLPLKFPDAEYDQIMMISYMVDGQGFLIINREVTACVGEDVEDLEYTPKPEFEGYFKVTN 311
Query: 329 EPDEMALLQRFFEHIRDVRPTVISTFNGDFFDWPFVENRAKFHGLNMFDEIGFAPD-SEG 387
+E+ LLQR+F H+++++P + T+NGDFFDWPF+E RA HG+ M +E+GF D ++G
Sbjct: 312 VKNEVELLQRWFYHMQELKPGIYVTYNGDFFDWPFIERRASHHGIKMNEELGFRCDQNQG 371
Query: 388 EYKSSYCTHMDCFRWVKRDSYLPQGSQGLKAVTQAKLGYNPLELDPELMTPYAYEKPQIL 447
E ++ + H+DCF WVKRDSYLPQGS GLKAVT+AKLGY+PLE++PE M +A EKPQ +
Sbjct: 372 ECRAKFACHLDCFAWVKRDSYLPQGSHGLKAVTKAKLGYDPLEVNPEDMVRFAMEKPQTM 431
Query: 448 SEYSVSDAVATYYLYMKYVHPFIFSLCTIIPLNPDEVLRKGTGTLCEMLLMV-------- 499
+ YSVSDAVATYYLYM YV+PFIFSL TIIP+ PDEVLRKG+GTLCEMLLMV
Sbjct: 432 ASYSVSDAVATYYLYMTYVNPFIFSLATIIPMVPDEVLRKGSGTLCEMLLMVEVSTYLPQ 491
Query: 500 -QAYQNSVLLPNKHTDPIERFYDGHLLESETYVGGHVESLEAGVFRSDLKNDFKIDPTVI 558
QAY+ +V+ PNK+ E+FY LLESETY+GGHVE LE+G +I
Sbjct: 492 AQAYKANVVCPNKNQADPEKFYQNQLLESETYIGGHVECLESG--------------QLI 537
Query: 559 DILLEDLPYALKFCIEVENNGNMEDVTNFEEIKQQITAQLTDLKINNKRNELPLIYHVDV 618
D L DL YA I VE M+ ++N++E+K +I +L L+ + R E PLIYH+DV
Sbjct: 538 DNLGRDLEYA----ITVEGKMRMDSISNYDEVKDEIKEKLEKLRDDPIREEGPLIYHLDV 593
Query: 619 ASMYPNIMTTNRLQ-----PDSMKDEKDCASCDFNRPGKSCDRRLKWAWRGEFFPAKMDE 673
A+MYPNI+ TNRLQ P S+ ++ C +CDFNRPGK+C R+L+W WRG F K +
Sbjct: 594 AAMYPNIILTNRLQVHLISPPSIVTDEICTACDFNRPGKTCLRKLEWVWRGVTFMGKKSD 653
Query: 674 YGMVKRALQNELFP-NKNPKSKKQFLTFEELSYSDQVSHIKKRLTDYSRKVYHRVKVTET 732
Y +K+ +++E N S K FL +L DQ S +K+RL Y +K Y RV
Sbjct: 654 YYHLKKQIESEFVDAGANIMSSKSFL---DLPKVDQQSKLKERLKKYCQKAYKRVLDKPI 710
Query: 733 VE-REAIVCQRENPFYVNTVRSFRDRRYEFKGLAKLWKGKLSKIKPDDVHSK-DEAKKMI 790
E REA +C RENPFYV+TVRSFRDRRYE+K L K+WKGKLS+ K K EA+ M+
Sbjct: 711 TEVREAGICMRENPFYVDTVRSFRDRRYEYKTLNKVWKGKLSEAKASGNSIKIQEAQDMV 770
Query: 791 VLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGITCLTGANIIQMARSVVERIGRPLE 850
V+YDSLQLAHK ILNSFYGYVMRKG+RWYSMEMAG+ TGA IIQ AR ++ERIG+PLE
Sbjct: 771 VVYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGVVTYTGAKIIQNARLLIERIGKPLE 830
Query: 851 LDTDGIWCILPKSFPENFEIKLRNGKKLFLSYPCSMLNYKVHQKYTNHQYQDLVDPMKFK 910
LDTDGIWC LP SFPENF K + KKL +SYPC MLN V + TN QYQ LVDP++
Sbjct: 831 LDTDGIWCCLPGSFPENFTFKTIDMKKLTISYPCVMLNVDVAKNNTNDQYQTLVDPVRKT 890
Query: 911 YQTKSDNSIFFEVDGPYKAMILPTSKEEGKGIKKRYAVFNEDGSLAELKGFELKRRGELQ 970
Y++ S+ SI FEVDGPYKAMI+P SKEEG IKKRYAVFN DG+LAELKGFE+KRRGEL+
Sbjct: 891 YKSHSECSIEFEVDGPYKAMIIPASKEEGILIKKRYAVFNHDGTLAELKGFEIKRRGELK 950
Query: 971 LIKNFQSDIFKLFLEGTTLESCYAAVATVANRWLDVLD---------------------- 1008
LIK FQ+++F FL G+TLE CY+AVA VA+RWLD+LD
Sbjct: 951 LIKVFQAELFDKFLHGSTLEECYSAVAAVADRWLDLLDVCEISCFFWVIYLIGFLSHFLQ 1010
Query: 1009 SKGAMLETEDLIELICENKSMSKTLKEYQGQKSTSITTARRLGEFLGEAMVKDAGLQCKF 1068
++G + +L++ I E+ +MSK+L +Y QKS ++TTA+RL EFLG MVKD GL+C++
Sbjct: 1011 NQGKDIADSELLDYISESSTMSKSLADYGEQKSCAVTTAKRLAEFLGVTMVKDKGLRCQY 1070
Query: 1069 IISSKPHNAPVTERAIPVAIFSSDLHVKRTFLRRWLLDSSLNDFDPRAIIDWDYYRERLA 1128
I++ +P PV+ERA+PVAIF+++ V + LR+W SS D R IIDW YY++RL+
Sbjct: 1071 IVACEPKGTPVSERAVPVAIFTTNPEVMKFHLRKWCKTSS--DVGIRLIIDWSYYKQRLS 1128
Query: 1129 SVVQKIITIPAALQNIKNPVPRVEHPDWLRKKIAVSEDKFKQTSLNRFFKSTK------- 1181
S +QK+ITIPAA+Q + NPVPRV HPDWL KK+ +DKF+Q L F S
Sbjct: 1129 SAIQKVITIPAAMQKVANPVPRVLHPDWLHKKVREKDDKFRQRKLVDMFSSANKDVVLDT 1188
Query: 1182 ----APPEVKDIEDSFDEHSANKSRIAKVTYKRKSKRRNGDTAXXXXXXXXXXXXXXXXD 1237
V+DIED E+ + + + ++ +
Sbjct: 1189 DLPVTKDNVEDIEDFCKENRPSVKGPKPIARSYEVNKKQSECEQQESWDTEFHDISFQNI 1248
Query: 1238 D----YVGWLQYQKTKWKIQHIDRKKREKLFGKTSRASD-----------RSALGNLIRK 1282
D Y GWL+ +K KWK+ +KKR ++S D R +G+ R+
Sbjct: 1249 DKSVNYQGWLELKKRKWKVTLEKKKKRRLGDLRSSNQVDTHEINQKVGQGRGGVGSYFRR 1308
Query: 1283 HVESYADKSWE---ILQCKPSIDLGVVEIYALIDRKIQLLKVNIPKTVLMNFKT--ENFP 1337
E+ W+ I+Q PS G + +++ + + ++IP+ +N K + +
Sbjct: 1309 PEEALTSSHWQVCTIIQLVPSPQSGQFFAWVVVEGLMLKIPLSIPRVFYINSKVPIDEYF 1368
Query: 1338 SGGIENCIVEKSNAELPNVKGINNESSSQLFKLTMSEDTYFNEVNKASSVLNNENVLGIY 1397
G C+ N LP+ + + + + + + ED + E K +++L + V GIY
Sbjct: 1369 QG---KCV----NKILPHGRPCYSLTEACV---KIQEDQFKKESKKRAALLADPGVEGIY 1418
Query: 1398 ESSISSNERVIMRLGTCIQFSSEKMGALGKGLQNGFHMKNLHPVEADR--YLQRFDLDIA 1455
E+ + I ++G + ++ A + Q+G+ + LH YL+R + +
Sbjct: 1419 ETKVPLEFSAICQIGCVCKIDNK---AKHRNTQDGWEVGELHMKTTTECHYLKR-SIPLV 1474
Query: 1456 YLLHFVTDIGYEFYFLYKAWEDVVEIFVLKPSTHAQEVSNKAIESLYNEIYEKKFEKLDK 1515
YL + T G Y LY ++ V+ P + E+ A+E + + L+
Sbjct: 1475 YLYNS-TSTGRAIYVLYCHVSKLMSAVVVDPF-NGNELLPSALERQFRD------SCLEL 1526
Query: 1516 YYDLIKINKNVSFNVNDYTELKRLLKDLSKMLQNIKEEKGSHTMVILQSPYTHRVAKLLQ 1575
D + + + F V+ + K + + + +EE T+ +++ P + + ++
Sbjct: 1527 SLDSLSWD-GIRFQVHYVDHPEAAKKIIQRAISEYREENCGPTVAVIECPDFTFMKEGIK 1585
Query: 1576 PLNAFPVVEIA--TAETHLPALNWQGQLMRKAVNHILSLGSWISNLITLSKYSNIPICNL 1633
L+ FP V I + ++WQ + A+ + W+ IT S+Y+++P+ N
Sbjct: 1586 ALDDFPCVRIPFNDDDNSYQPVSWQRPAAKIAMFRCAAAFQWLDRRITQSRYAHVPLGNF 1645
Query: 1634 KVDNLGYIIDLMYARQLKKNNIVLWWNDKSPLPDHGGVERDFDPRKAELM-TDLVFPIMN 1692
+D L + ID+ +R L+ VLW +D +PD GG+ + E+ T LVFP
Sbjct: 1646 GLDWLTFTIDIFLSRALRDQQQVLWVSDNG-VPDLGGINNEEAFFADEVQQTSLVFP--- 1701
Query: 1693 NPDIYDDVIFEISVYNSVVNTVLSSTMLNEAEG-------TDLAQNSTSKEESFGFVEDX 1745
Y V E+ ++N VN +L S ++NE EG D+ + ++ F E
Sbjct: 1702 --GAYRKVSVELKIHNLAVNALLKSNLVNEMEGGGFMGFEQDVNPRGINSNDNTSFDE-- 1757
Query: 1746 XXXXXXXXXXXXXKELWDDALGD-----NITADSLVHAFIGWVYNPDAKLFDYALRYHIH 1800
K+L L D NI ADS++ W+ +P +KL D AL +H
Sbjct: 1758 --TTGCAQAFRVLKQLIHSCLTDVRKSKNIYADSILQRLSWWLCSPSSKLHDPALHLMLH 1815
Query: 1801 TLTQKAVLQLINEFKLAGSSLIFADRNKLLIKTQKRSVENSYAYGQYLMKAIRSKPMFAY 1860
+ QK L+ + + G+ +I+AD +K++I T K + + AY + L+ +R++ + +
Sbjct: 1816 KVMQKVFALLLTDLRRLGAIIIYADFSKVIIDTVKFDLSAAKAYCESLLSTVRNRLVSSL 1875
Query: 1861 L-----DLK------------------------------------IDRYWDVLIWMDKY- 1878
L DLK I+ W V + +Y
Sbjct: 1876 LDIHVYDLKSHGLHSFSCHDFCASPLTYNYAGIRADDEISLDEVTIEPKWSVARHLPEYI 1935
Query: 1879 -----NYGGRACLQIEDKEVQS-----FQAYSHWHI---KDFLPAIYQQEFDDWLVVILD 1925
N C E+K+ + F +H+ +DF+ I + FD W I +
Sbjct: 1936 EVWRQNPHSNQCSFSENKKHVATHGPFFLDTDAFHLSWQRDFIIIIAKFIFDPWKFAIEN 1995
Query: 1926 SMVKTK-------EAYHERNAST----------QRLTQLPKNTLADSDVDSQTDSLGGFT 1968
++ E E+ ST ++ + + ++D+ S G ++
Sbjct: 1996 KKGSSESLEAQMIEYLREQIGSTFINMLVKKVDDIMSHMKEINVSDASRVSGQAPKGDYS 2055
Query: 1969 HNFSKALIKRAEKLYKNQQEYILDPNFGKDYLSPTIPGSHLVVKNPLLELVKYXXXXXXX 2028
F + + QQ+ +L F D++ S+L+ N +LE +
Sbjct: 2056 LEFIQVISAVLALDQNVQQDVLLKTLFITDFIHK----SNLISGNVVLETMFTNRAGFFF 2111
Query: 2029 XXXXXXEGRALRKELLKTFEIREFDRLAEFKDPSTSFVIPSFICEHCSYISDIDICRESM 2088
+RK LLK +++E AEF DP SF++P+ C +C D+DICR+
Sbjct: 2112 EW-------VMRKSLLKYIKVKECAAEAEFLDPGPSFILPNVACSNCDAYRDLDICRDPA 2164
Query: 2089 ---ERVFICQS--CNRSLNKNLIEEHVIERLQAQVASFITQDVKCNKCHKIKEDAMSPYC 2143
E+ + C C + ++ +E ++E ++ + + QDV C +C+++K ++ C
Sbjct: 2165 LLTEKEWSCADTQCGKIYDREQMESSLLEMVRQRERMYHMQDVVCIRCNQVKAAHLTEQC 2224
Query: 2144 PCSGKWELAVSKESFMAQLQIFKNLAESFDFRTLKETLN 2182
CSG + S F +++IF ++A+ FR L+E ++
Sbjct: 2225 ECSGSFRCKESGSEFSKRMEIFMDIAKRQKFRLLEEYIS 2263
>CE17767 [L] KOG1798 DNA polymerase epsilon catalytic subunit A
Length = 2144
Score = 1296 bits (3354), Expect = 0.0
Identities = 779/1979 (39%), Positives = 1115/1979 (55%), Gaps = 156/1979 (7%)
Query: 40 DEIDEMMGFPRFIPSPALSDSKVGWLSNMHPTIISQEMLEEEGNLHSATVSGISGVDFYF 99
DEID +GF R+ L + K G+L N+ P+ E+++E+ T IS VD++F
Sbjct: 29 DEIDAKLGFSRYT---GLQEKK-GFLINIQPS----ELVDEQ------TKVIISVVDYFF 74
Query: 100 IDEEGGSFKTTVTYDPYFFVSCTDETRIHDIEEYLKKTLEQCIKKVELVLKDDLAMNNHL 159
I + FK + + PYF+++ D + YL K VE + ++DL + +HL
Sbjct: 75 ISDMDERFKISYPFRPYFYIATLDGFEFQ-VSSYLSKKYG-AQTAVEHMDREDLDLKDHL 132
Query: 160 VGLKKHLIKLSFSNSNQLFEARRILRPILKINEDENGKKDIYNTGSDYSTR--------- 210
GLKK IKLSF+++ +L + R+ L P+++ N D K+ Y +DY R
Sbjct: 133 SGLKKTYIKLSFTSTVELIKIRKELMPLVRKNTDRIKKESAY---ADYLARNLSGKGGDS 189
Query: 211 -------DVKTLIEDIREYDVPYHVRVSIDKNIRVGKWYAVSAQG------LVELEEKVT 257
D+ I DIREYDVP+H+RVSID+ I VG WY V G + + +
Sbjct: 190 KDQQLNGDILNQIVDIREYDVPFHMRVSIDEKIFVGLWYDVKGIGPNRVPTIKRKDLPLF 249
Query: 258 FADPVVLAFDIETTKAPLKFPDSAIDQIMMISYMIDGEGFLITNREIISEDIEDFEYTPK 317
A P VLAFDIETTK PLKFPD D+IMMISYM+DG GFLI NREI+S DI FEYTPK
Sbjct: 250 HAKPKVLAFDIETTKLPLKFPDRESDEIMMISYMVDGRGFLIINREIVSADINAFEYTPK 309
Query: 318 DEYKGQFAIFNEPDEMALLQRFFEHIRDVRPTVISTFNGDFFDWPFVENRAKFHGLNMFD 377
EY G+F ++NE DE AL+++FF+H VRP ++ T+NGDFFDWPFVE RAK G NM
Sbjct: 310 AEYIGEFTVWNEKDEAALIRKFFDHFLQVRPNIVVTYNGDFFDWPFVEARAKIRGFNMER 369
Query: 378 EIGFAPDSEGEYKSSYCTHMDCFRWVKRDSYLPQGSQGLKAVTQAKLGYNPLELDPELMT 437
EIGF+ DS EYKS C HMD FRWVKRDSYLP GSQ LKAVT+AKL Y+P+E++PELM
Sbjct: 370 EIGFSKDSADEYKSRNCIHMDAFRWVKRDSYLPVGSQNLKAVTKAKLRYDPVEVEPELMC 429
Query: 438 PYAYEKPQILSEYSVSDAVATYYLYMKYVHPFIFSLCTIIPLNPDEVLRKGTGTLCEMLL 497
A E+PQ L+ YSVSDAV+TYYLYMKYVH FIF+LCTIIPL D+VLRKG+GTLCE LL
Sbjct: 430 KMAREQPQQLANYSVSDAVSTYYLYMKYVHQFIFALCTIIPLGADDVLRKGSGTLCEALL 489
Query: 498 MVQAYQNSVLLPNKHTDPIERFY--DGHLLESETYVGGHVESLEAGVFRSDLKNDFKIDP 555
MV+A+ N+++ PNK+T P E + DGH +ESETYVGGHVE+LEAGVFR+D+ F++
Sbjct: 490 MVEAFHNNIVFPNKYTGPEETRFSKDGHRVESETYVGGHVEALEAGVFRADIPAKFRLSV 549
Query: 556 TVIDILLEDLPYALKFCIEVENNGNMEDVTNFEEIKQQITAQLTDLKINNKRNELPLIYH 615
++ L ++ L+ + E ++ V +F+E ++ + R E P IYH
Sbjct: 550 PALEQLKSEIQETLRKELAREFEVTLDQVVDFDEQCAEVQDAFDGMINVPTRLENPRIYH 609
Query: 616 VDVASMYPNIMTTNRLQPDSMKDEKDCASCDFNRPGKSCDRRLKWAWRGEFFPAKMDEYG 675
+DV +MYPNI+ TNRLQP +M E+ C C +N+P C R + W WRGE PA EY
Sbjct: 610 LDVGAMYPNIILTNRLQPCAMVTEEICMGCSYNKPDAECKRTMAWEWRGELTPATRGEYQ 669
Query: 676 MVKRALQNELFPNKNPKSKKQFLTFEELSYSDQVSHIKKRLTDYSRKVYHRVKVTETVER 735
+ + L+ E F K PK F L S++ + KR+ DYSR+VY + +T R
Sbjct: 670 QIMQQLEAESF-GKPPKH------FHMLERSEREAIEMKRIKDYSRRVYGKTHLTRLEMR 722
Query: 736 EAIVCQRENPFYVNTVRSFRDRRYEFKGLAKLWKGKLSKIK-PDDVHSKDEAKKMIVLYD 794
E +CQREN FYV TV++FRDRRYE+K + K KG+ + + +D+ + +K +VLY+
Sbjct: 723 ETTICQRENHFYVETVKAFRDRRYEYKDMLKKAKGRFDQAQATNDLATMTTSKLEMVLYE 782
Query: 795 SLQLAHKVILNSFYGYVMRKGSRWYSMEMAGITCLTGANIIQMARSVVERIGRPLELDTD 854
SLQLAHK ILNSFYGYVMRKGSRW+SMEMAGI C TGANII+ AR +VE+IG PLELDTD
Sbjct: 783 SLQLAHKCILNSFYGYVMRKGSRWFSMEMAGIVCHTGANIIREARKLVEQIGTPLELDTD 842
Query: 855 GIWCILPKSFPENFEIKLRNGKK--LFLSYPCSMLNYKVHQKYTNHQYQDLVDPMKFKYQ 912
GIWC++P SFPEN KL+N K+ + +SYP +MLN V++ +TNHQY L Y
Sbjct: 843 GIWCLIPASFPENVTFKLKNHKRSSVTVSYPGAMLNALVYEGFTNHQYHTL--EKDGSYS 900
Query: 913 TKSDNSIFFEVDGPYKAMILPTSKEEGKGIKKRYAVFNEDGSLAELKGFELKRRGELQLI 972
S+NSI+FEVDGPY+ MILP SKEEGK +KKRYAVFN DGSLAE+KGFELKRRGEL +I
Sbjct: 901 KSSENSIYFEVDGPYQCMILPASKEEGKKLKKRYAVFNLDGSLAEMKGFELKRRGELNII 960
Query: 973 KNFQSDIFKLFLEGTTLESCYAAVATVANRWLDVLDSKGAMLETEDLIELICENKSMSKT 1032
K+FQ +FK FL G TLE Y AVA A+ WLD+L S GA L E+L +LI EN+SMS+
Sbjct: 961 KHFQGCVFKTFLNGKTLEETYKAVAADADHWLDILHSHGADLTDEELFDLISENRSMSRK 1020
Query: 1033 LKEYQGQKSTSITTARRLGEFLGEAMVKDAGLQCKFIISSKPHNAPVTERAIPVAIFSSD 1092
L++Y QKSTSI+TA+RL EFLG+ MVKDAGL C FIIS P APVTERAIPVAIF SD
Sbjct: 1021 LEDYGAQKSTSISTAKRLAEFLGDDMVKDAGLACMFIISKHPIGAPVTERAIPVAIFKSD 1080
Query: 1093 LHVKRTFLRRWLLDSSLN-DFDPRAIIDWDYYRERLASVVQKIITIPAALQNIKNPVPRV 1151
V+ ++R+W N D D R ++DWDYY ER S +QKIITIPAALQ I NPVPRV
Sbjct: 1081 AKVRSHYIRKWTKQVDFNEDTDIRDMLDWDYYLERFGSCIQKIITIPAALQGISNPVPRV 1140
Query: 1152 EHPDWLRKKIAVSEDKFKQTSLNRFFKSTKAPP----------EVKDIEDSFDEHSANKS 1201
HPDWL+ KI D +Q +N+ F + + P D + + ++ ++
Sbjct: 1141 PHPDWLQNKIRNKFDAHRQPRINQIFAACQKPSTSQMDNGKRRRTPDDDVASEDAMDSQD 1200
Query: 1202 RIAKVTYKRKSKRRNGDTAXXXXXXXXXXXXXXXXDDYVGWLQYQKTKWKIQHIDRKKRE 1261
I K +R +T + W+ + K KW++Q +RK +
Sbjct: 1201 DIIIDDDKENGAKRQKNTKKVHTTEVVLEKKTLVEHGFDEWMGFLKKKWRVQRKERKTQ- 1259
Query: 1262 KLFGKTSRASDRSALGNLIRKHVESYADKSWEILQCKPSIDLGVVEIYALIDRKIQLLKV 1321
+ D + ++R E+ DK W IL +P+ D ++ + ++ + +
Sbjct: 1260 ------LSSKDSDVVEAIVRGAREAEHDKEWHILSVEPTADASFFNVWLAVQGQMHKVIM 1313
Query: 1322 NIPKTVLMNFKTENFPSGGIENCIVEKSNAELPNVKGINNESSSQLFKLTMSEDTYFNEV 1381
I + ++++ + I + ++++ L++ E+ +
Sbjct: 1314 KIGRRIIVDSRAPRGDRDTIRRILP-------------HHKTPGFLYEFRTDENQLTALM 1360
Query: 1382 NKASSVLNNENVLGIYESSISSNERVIMRLGTCIQFSSEKMGALGKGLQNGFH---MKNL 1438
+K S + + GIYES + ++ R +++LG+ ++ G+ G H ++NL
Sbjct: 1361 DKLYSETCSSTIDGIYESEVPTSFRAVLQLGSIVR--------PDHGISLGGHQLTLENL 1412
Query: 1439 HPVEADRYLQRFDLDIAYLLHFVTDIGYEFYFLYKAWEDVVEIFVLKPST---------H 1489
P+E YL D FLYK +D ++ L S+ +
Sbjct: 1413 KPMEKAPYLP-------------LDQKIRTIFLYKFSQDSRHVYSLIDSSGSAAYFYIVN 1459
Query: 1490 AQEVSNKAIESLYNEIYEKKFEKLDKYYDLIKINKNVSFNVNDYTELKRLLKDLSKMLQN 1549
+V ++SLY Y K + L ++++ F V ++ + L + L+
Sbjct: 1460 TGDVQMPNMDSLYTSAYTKMMS--TERGQLCHTSESMPFTVKRFSSNTECERQLGRALRV 1517
Query: 1550 IKEEKGSHTMVILQSPY-THRVAKLLQPLNAFPVVEIATAE--THLPALNWQGQLMRKAV 1606
+E +V+L S R+A+ L L FP V++ E + L ++WQ + R+ +
Sbjct: 1518 YREVSSKTAIVLLLSDTDPFRLARKLPNLGLFPNVQLHITEPSSLLNQIDWQKVVARRVL 1577
Query: 1607 NHILSLGSWISNLITLSKYSNIPICNLKVDNLGYIIDLMYARQLKKNNIVLWWNDKSPLP 1666
H + ++++ + ++Y +PI NL D+ + +DL++AR L+K+ L W ++ P
Sbjct: 1578 QHYFNSFFFLADYLEWARYLRVPIGNLPADHALFGLDLLFARNLQKSGHAL-WATRASRP 1636
Query: 1667 DHGGVERDFDPRKAELMTDLVFP---IMNNPDIYDDVIFEISVYNSVVNTVLSSTMLNEA 1723
D GG E D D R + L ++N + E+ + V ++ + + EA
Sbjct: 1637 DLGGKEMD-DVRLSVDWNPLSIDDTVLLNRETFCETACVELQLSAVAVTALVQRSRVLEA 1695
Query: 1724 EGTD-----LAQNSTSKEESFGFVEDXXXXXXXXXXXXXXKELWDDALGD---------N 1769
EG D + N+ +++ G + ++ L + N
Sbjct: 1696 EGADDVVTFDSMNTIAQQSVTGGAVNSIACYDEGAAVDATIKVLKQMLTECVRHIAHQGN 1755
Query: 1770 ITADSLVHAFIGWVYNPDAKLFDYALRYHIHTLTQKAVLQLINEFKLAGSSLIFADRNKL 1829
AD +V W+ A LFD AL + L K VL L E + G+ +I A KL
Sbjct: 1756 ARADEVVMTVSRWLNTRSALLFDAALTRSVSVLESKLVLLLCAECERIGAKVIHATAQKL 1815
Query: 1830 LIKTQKRSVENSYAYGQYLMKAIRSKPMFAYLDLKIDRYWDVLIWMDKYNYGGRACLQ-- 1887
++ T K + E + + + L++++ + +FA L + +++D ++WMD +N+ G +
Sbjct: 1816 VLNTGKSTSEEAKGFAEMLIQSLSTNVVFAALHITPVKFFDAMLWMDAHNHTGIRISEKT 1875
Query: 1888 ------IEDKEVQS---FQAYSHWHIKDFLP--AIYQQEFDDWLVVILDSMVKTKEAYH 1935
I D+E S F+ + W I + +P A Q+EF + + ++T H
Sbjct: 1876 ESSPDVIADEEESSCTEFETTAIWKIAEEMPTEANIQEEFLQMIGAYILEFLETNRKMH 1934
Score = 60.8 bits (146), Expect = 2e-08
Identities = 30/121 (24%), Positives = 60/121 (48%), Gaps = 8/121 (6%)
Query: 2062 STSFVIPSFICEHCSYISDIDICRESMERVFICQSCNRSLNKNLIEEHVIERLQAQVASF 2121
ST+ + + C CS S++ + S + + C +C LN ++I+ + +RL + ++
Sbjct: 2020 STTLFVSNVFCNSCSQASNVFL--SSTDEILTCATCQSKLNSDVIDMMICDRLNQLLTAY 2077
Query: 2122 ITQDVKCNKCHKIKEDAMSPYCPCSGKWELAVS------KESFMAQLQIFKNLAESFDFR 2175
QD +C KC ++ D +S YC C ++ ++ + S + + I +N A S +
Sbjct: 2078 QIQDHQCTKCKSVRHDTLSMYCECCSQFIPQITPAQLKHEASTVETVSIVRNFALSSELA 2137
Query: 2176 T 2176
T
Sbjct: 2138 T 2138
>ECU10g1210 [L] KOG1798 DNA polymerase epsilon catalytic subunit A
Length = 1799
Score = 848 bits (2191), Expect = 0.0
Identities = 472/1123 (42%), Positives = 682/1123 (60%), Gaps = 70/1123 (6%)
Query: 71 TIISQEMLEE--------EGN------LHSATVS---GISGVDFYFIDEEGGSFKTTVTY 113
T++ E+LEE EG L+ ATV+ G Y ID EG F + Y
Sbjct: 3 TVMRDELLEEQYGFVPYYEGRRREGWLLNYATVTLKDGRMKTKLYLIDGEGVEFLVKIPY 62
Query: 114 DPYFFVSCTDETRIHDI-EEYLKKTLEQCIKKVELVLKDDLAMNNHLVGLKKHLIKLSFS 172
P F V +D +D+ EEYL+K I +E + D NHL +K+ F
Sbjct: 63 FPSFLVKASD----YDVVEEYLRKRYSGEIHDIERTHRVDFKEYNHLSKEPGVFLKVRFK 118
Query: 173 NSNQLFEARRILRPILKINEDENGKKDIYNTGSDYSTRDVKTLIEDIREYDVPYHVRVSI 232
+A + +R ++ N+ + ++D Y+ + + + I I E+D+P V +
Sbjct: 119 TDTGFGDAVKDVRRVVARNKVQ--RRDEYDCFGEGRGLNAEDFIVSICEHDIPVEVCAAN 176
Query: 233 DKNIRVGKWYAVSAQG---LVELEEKVTFADPVVLAFDIETTKAPLKFPDSAIDQIMMIS 289
D IR G+WY G ++E E++ F D +LAFDIET+K PLKFP++ D++MMIS
Sbjct: 177 DLGIRCGRWYGFRYTGEMYVIEKSERIVFPDLRILAFDIETSKRPLKFPNADSDEVMMIS 236
Query: 290 YMIDGEGFLITNREIISEDIEDFEYTPKDEYKGQFAIFNEPDEMALLQRFFEHIRDVRPT 349
+G G LI NR ++S+DI FEY+PK++ + F NE E +L RF E I+ RP
Sbjct: 237 VKTEGYGELIVNRGLVSKDIRGFEYSPKEDMQCTFCAVNESSEEGVLIRFVETIQRHRPH 296
Query: 350 VISTFNGDFFDWPFVENRAKFHGLNMFDEIGFAPDSEGEYKSSYCTHMDCFRWVKRDSYL 409
+I+TFNG FD+PF+E R +G+++ + GF E Y S + H+DC++WV+RDSYL
Sbjct: 297 LITTFNGALFDFPFLEKRMLRYGISLRETAGFVRRDE-YYISPFIVHLDCYKWVRRDSYL 355
Query: 410 PQGSQGLKAVTQAKLGYNPLELDPELMTPYAYEKPQILSEYSVSDAVATYYLYMKYVHPF 469
P GSQGLKAVT+AKLGY P E+DPE M A P+ + YS SD+VATY+LY+KYV P
Sbjct: 356 PAGSQGLKAVTKAKLGYFPDEVDPEDMVGLAVSDPERMGSYSASDSVATYFLYIKYVQPH 415
Query: 470 IFSLCTIIPLNPDEVLRKGTGTLCEMLLMVQAYQNSVLLPNKHTDPIERFYDGHLLESET 529
+FS+C++IPL P L +G+GTLCE LL+ +A VL+P K + + ++GH+ ES T
Sbjct: 416 VFSMCSLIPLPPTSALCQGSGTLCEALLISEATAYGVLVPEKRRETKMQEHNGHIAESIT 475
Query: 530 YVGGHVESLEAGVFRSDLKNDFKIDPTVIDILLEDLPYALKFCIEVENNGNMEDVTNFEE 589
YVGGHVE L++G+FRSD + +F +D ID + ALK E FE+
Sbjct: 476 YVGGHVECLKSGIFRSDFEYEFDVDKEFIDTV------ALKI---DEMLSEYRGEEGFED 526
Query: 590 IKQQITAQLTDLKINNKRNELPLIYHVDVASMYPNIMTTNRLQPDSMKDEKDCASCDFNR 649
++ ++ L + + +R LIYH+DV +MYPNI+ TN+LQP ++ DE C CDF+
Sbjct: 527 MRGKVLRNLQENRGGFRRE--GLIYHLDVGAMYPNIILTNKLQPIAIVDEDACIRCDFSD 584
Query: 650 PGKSCDRRLKWAWRGEFFPAKMDEYGMVKRALQNELFPNKNPKSKKQFLTFEELSYSDQV 709
C +R++W + E+ PA +E +++ ++ E K F D+
Sbjct: 585 ESNGCKKRMEWTLKVEYIPAGREETERIRKQIRRE----------KGFA-------GDEN 627
Query: 710 SHIKKRLTDYSRKVYHRVKVTETVEREAIVCQRENPFYVNTVRSFRDRRYEFKGLAKLWK 769
+++R YS+ Y R KV E+ R + VCQRE PFYV TVR FRD+RY +K L +
Sbjct: 628 EELRQRARRYSKDTYRRAKVRESCIRSSTVCQREIPFYVETVRKFRDQRYVYKKLHSQAQ 687
Query: 770 GKLSKIKPDDVHSKDEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGITCL 829
D+ + A K +V+Y SLQ+AHK +LNSFYGYVMRK SRWYSMEMA I C
Sbjct: 688 KAFESASSDE--ERKHAMKSVVVYSSLQIAHKCVLNSFYGYVMRKSSRWYSMEMAAIVCN 745
Query: 830 TGANIIQMARSVVERIGRPLELDTDGIWCILPKSFPENFEIKLRNGKKLFLSYPCSMLNY 889
G NII+ A+ VVE+IG LELDTDGIWCI+P S ++ L +G++ S+ S+LN+
Sbjct: 746 VGGNIIKRAKEVVEKIGISLELDTDGIWCIVPSSLISSY--TLPSGRR--FSFLSSLLNH 801
Query: 890 KVHQKYTNHQYQDLVDPMKFKYQTKSDNSIFFEVDGPYKAMILPTSKEEGKGIKKRYAVF 949
V +++TN QYQ+ VD KY +++NSIFFE+DGPY+AM+LP+S EE K +KKRYA+
Sbjct: 802 FVCKEFTNWQYQERVDG---KYVMRAENSIFFEIDGPYRAMLLPSSTEESKLLKKRYAII 858
Query: 950 NEDGSLAELKGFELKRRGELQLIKNFQSDIFKLFLEGTTLESCYAAVATVANRWLDVLDS 1009
+ + +AELKGFE+KRRGEL+++K FQ ++F FL+G+ LE CY ++A V WLD+L S
Sbjct: 859 DSNNRIAELKGFEIKRRGELEIVKKFQEELFLHFLDGSNLEECYESLAGVCRYWLDILKS 918
Query: 1010 KGAMLETEDLIELICENKSMSKTLKEYQGQKSTSITTARRLGEFLGEAMVKDAGLQCKFI 1069
+G L+ + ++EL+ E++SMSK EY+G+KS TA R+ E LGE ++++ L+C++I
Sbjct: 919 RGEYLDDDTILELLSESRSMSKGFGEYRGRKSNLTVTALRMSELLGEGILEEK-LKCEYI 977
Query: 1070 ISSKPHNAPVTERAIPVAIFSSDLHVKRTFLRRWLLDSSLNDFDPRAIIDWDYYRERLAS 1129
++ P N V ERAIPV +F S+ K FLRRW+ L D RAIIDWDYYR+RL
Sbjct: 978 VAVYPENGSVAERAIPVVVFRSE--QKEEFLRRWMGRDYLGDI--RAIIDWDYYRQRLEC 1033
Query: 1130 VVQKIITIPAALQNIKNPVPRVEHPDWLRKKIAVSEDKFKQTS 1172
VVQ+++ +PA Q ++NP+ ++ P W + + K+TS
Sbjct: 1034 VVQRMVILPALSQGVRNPLREIQVPVWANSGAGLGDFGLKRTS 1076
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 130,858,260
Number of Sequences: 60738
Number of extensions: 5878203
Number of successful extensions: 15441
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 15319
Number of HSP's gapped (non-prelim): 17
length of query: 2185
length of database: 30,389,216
effective HSP length: 122
effective length of query: 2063
effective length of database: 22,979,180
effective search space: 47406048340
effective search space used: 47406048340
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)