ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0823 good Z KOG0980 Cytoskeleton Actin-binding protein SLA2/Huntingtin-interacting protein Hip1
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0823 Weakly similar to YNL243w SP|P33338 SLA2
cytoskeleton assembly control protein singleton
(679 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL243w [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-intera... 367 e-101
SPAC688.11 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-int... 283 8e-76
Hs14760485 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-int... 92 3e-18
7294543 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-intera... 78 4e-14
CE29640 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-intera... 78 5e-14
CE00540 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-intera... 78 5e-14
CE17638 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-intera... 67 9e-11
Hs7427515 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-inte... 59 2e-08
CE08573 [S] KOG4787 Uncharacterized conserved protein 49 3e-05
7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related... 46 2e-04
Hs10864047 [TU] KOG0998 Synaptic vesicle protein EHS-1 and relat... 45 4e-04
YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115 44 6e-04
Hs15011904 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prot... 44 0.001
7298332 [BD] KOG0996 Structural maintenance of chromosome protei... 43 0.001
YHR023w [Z] KOG0161 Myosin class II heavy chain 43 0.002
Hs14149661 [U] KOG4809 Rab6 GTPase-interacting protein involved ... 43 0.002
At2g01600 [TU] KOG0251 Clathrin assembly protein AP180 and relat... 43 0.002
Hs7669506 [Z] KOG0161 Myosin class II heavy chain 42 0.003
Hs20542063 [Z] KOG0161 Myosin class II heavy chain 42 0.003
CE27773 [Z] KOG0517 Beta-spectrin 42 0.003
Hs4503593 [TU] KOG0998 Synaptic vesicle protein EHS-1 and relate... 41 0.005
Hs13124879 [Z] KOG0161 Myosin class II heavy chain 41 0.005
Hs13124875 [Z] KOG0161 Myosin class II heavy chain 41 0.005
YIL138c [Z] KOG1003 Actin filament-coating protein tropomyosin 41 0.007
SPCC645.05c [Z] KOG0161 Myosin class II heavy chain 41 0.007
7292323 [S] KOG4643 Uncharacterized coiled-coil protein 41 0.007
Hs8923940 [Z] KOG0161 Myosin class II heavy chain 40 0.009
CE15746 [DY] KOG0977 Nuclear envelope protein lamin intermediate... 40 0.009
7293601 [T] KOG0577 Serine/threonine protein kinase 40 0.009
YLR337c [Z] KOG4462 WASP-interacting protein VRP1/WIP contains W... 40 0.012
7303911 [D] KOG4593 Mitotic checkpoint protein MAD1 40 0.012
Hs4557773 [Z] KOG0161 Myosin class II heavy chain 40 0.015
Hs7427513 [ZR] KOG4568 Cytoskeleton-associated protein and relat... 39 0.020
Hs4505301 [Z] KOG0161 Myosin class II heavy chain 39 0.020
Hs20532997 [Z] KOG0161 Myosin class II heavy chain 39 0.020
Hs14702162 [ZR] KOG4568 Cytoskeleton-associated protein and rela... 39 0.020
Hs11024712 [Z] KOG0161 Myosin class II heavy chain 39 0.020
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 39 0.020
Hs20558376 [Z] KOG0161 Myosin class II heavy chain 39 0.026
Hs18375528 [A] KOG1295 Nonsense-mediated decay protein Upf3 39 0.034
Hs12711674 [A] KOG1295 Nonsense-mediated decay protein Upf3 39 0.034
CE02903 [TU] KOG0998 Synaptic vesicle protein EHS-1 and related ... 39 0.034
At5g57200 [TU] KOG0251 Clathrin assembly protein AP180 and relat... 39 0.034
YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein 38 0.045
CE28392 [U] KOG4809 Rab6 GTPase-interacting protein involved in ... 38 0.045
7303314 [S] KOG0992 Uncharacterized conserved protein 38 0.045
YNL079c [Z] KOG1003 Actin filament-coating protein tropomyosin 38 0.058
Hs4885399 [D] KOG0964 Structural maintenance of chromosome prote... 38 0.058
Hs22035581 [D] KOG3859 Septins (P-loop GTPases) 38 0.058
Hs22035577 [D] KOG3859 Septins (P-loop GTPases) 38 0.058
Hs21361478 [D] KOG3859 Septins (P-loop GTPases) 38 0.058
CE18407 [O] KOG4185 Predicted E3 ubiquitin ligase 38 0.058
YIL149c [S] KOG4674 Uncharacterized conserved coiled-coil protein 37 0.076
HsM14719396 [D] KOG3859 Septins (P-loop GTPases) 37 0.076
Hs5453642 [D] KOG0018 Structural maintenance of chromosome prote... 37 0.076
Hs4506751 [ZR] KOG4568 Cytoskeleton-associated protein and relat... 37 0.076
Hs4505987 [R] KOG1899 LAR transmembrane tyrosine phosphatase-int... 37 0.076
Hs14764231 [D] KOG0018 Structural maintenance of chromosome prot... 37 0.076
CE21149 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC... 37 0.076
7296950 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein... 37 0.076
HsM4885113 [BD] KOG0996 Structural maintenance of chromosome pro... 37 0.099
Hs4505257 [R] KOG3529 Radixin moesin and related proteins of the... 37 0.099
Hs21361252 [BD] KOG0996 Structural maintenance of chromosome pro... 37 0.099
CE20131 [T] KOG0976 Rho/Rac1-interacting serine/threonine kinase... 37 0.099
SPBC29A10.04 [D] KOG0018 Structural maintenance of chromosome pr... 37 0.13
SPAC1556.01c [L] KOG0962 DNA repair protein RAD50 ABC-type ATPas... 37 0.13
Hs7705348 [Z] KOG0247 Kinesin-like protein 37 0.13
Hs4758200 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prote... 37 0.13
At1g79280 [S] KOG4674 Uncharacterized conserved coiled-coil protein 37 0.13
7302958 [Z] KOG0240 Kinesin (SMY1 subfamily) 37 0.13
7301097 [D] KOG0018 Structural maintenance of chromosome protein... 37 0.13
YLL026w [O] KOG1051 Chaperone HSP104 and related ATP-dependent C... 36 0.17
SPCC162.06c [U] KOG1655 Protein involved in vacuolar protein sor... 36 0.17
Hs4759058 [T] KOG2008 BTK-associated SH3-domain binding protein SAB 36 0.17
Hs20373153 [Z] KOG0161 Myosin class II heavy chain 36 0.17
Hs12667788 [Z] KOG0161 Myosin class II heavy chain 36 0.17
CE18406 [O] KOG4185 Predicted E3 ubiquitin ligase 36 0.17
7292646 [R] KOG4436 Predicted GTPase activator NB4S/EVI5 (contai... 36 0.17
YBL063w [Z] KOG0243 Kinesin-like protein 36 0.22
SPBC19F8.03c [TU] KOG0251 Clathrin assembly protein AP180 and re... 36 0.22
Hs6005904 [K] KOG4673 Transcription factor TMF TATA element modu... 36 0.22
Hs4507659 [S] KOG4674 Uncharacterized conserved coiled-coil protein 36 0.22
Hs15313972 [Z] KOG0161 Myosin class II heavy chain 36 0.22
Hs13124877 [Z] KOG0161 Myosin class II heavy chain 36 0.22
CE09349 [Z] KOG0161 Myosin class II heavy chain 36 0.22
At5g62410 [BD] KOG0933 Structural maintenance of chromosome prot... 36 0.22
At4g24270 [A] KOG0128 RNA-binding protein SART3 (RRM superfamily) 36 0.22
YKL014c [S] KOG1791 Uncharacterized conserved protein 35 0.29
Hs11342672 [Z] KOG0161 Myosin class II heavy chain 35 0.29
CE25302 [D] KOG0964 Structural maintenance of chromosome protein... 35 0.29
CE04618 [Z] KOG0161 Myosin class II heavy chain 35 0.29
At5g48600 [BD] KOG0996 Structural maintenance of chromosome prot... 35 0.29
7297163 [R] KOG0249 LAR-interacting protein and related proteins 35 0.29
7291892 [Z] KOG0161 Myosin class II heavy chain 35 0.29
Hs4502781_1 [Z] KOG0242 Kinesin-like protein 35 0.29
YNL250w [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC... 35 0.38
SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 35 0.38
Hs6857804 [Z] KOG4280 Kinesin-like protein 35 0.38
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 35 0.38
Hs4758646 [Z] KOG4280 Kinesin-like protein 35 0.38
Hs4502395 [T] KOG2751 Beclin-like protein 35 0.38
Hs20336209 [K] KOG1015 Transcription regulator XNP/ATRX DEAD-box... 35 0.38
Hs20336207 [K] KOG1015 Transcription regulator XNP/ATRX DEAD-box... 35 0.38
Hs20336205 [K] KOG1015 Transcription regulator XNP/ATRX DEAD-box... 35 0.38
CE16631 [Z] KOG0244 Kinesin-like protein 35 0.38
CE08691 [U] KOG0999 Microtubule-associated protein Bicaudal-D 35 0.38
CE00283 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin deg... 35 0.38
At3g44800 [DR] KOG1987 Speckle-type POZ protein SPOP and related... 35 0.38
At2g38720 [DZ] KOG4302 Microtubule-associated protein essential ... 35 0.38
7303885 [U] KOG4809 Rab6 GTPase-interacting protein involved in ... 35 0.38
7303561 [S] KOG4674 Uncharacterized conserved coiled-coil protein 35 0.38
SPAC1486.04c [S] KOG4674 Uncharacterized conserved coiled-coil p... 35 0.49
Hs7662208 [T] KOG1451 Oligophrenin-1 and related Rho GTPase-acti... 35 0.49
Hs5453591 [BD] KOG0933 Structural maintenance of chromosome prot... 35 0.49
Hs18644730 [B] KOG1973 Chromatin remodeling protein contains PHD... 35 0.49
CE26070 [Z] KOG0613 Projectin/twitchin and related proteins 35 0.49
CE07306 [Z] KOG0161 Myosin class II heavy chain 35 0.49
CE04747 [OE] KOG1282 Serine carboxypeptidases (lysosomal catheps... 35 0.49
CE03710 [S] KOG2911 Uncharacterized conserved protein 35 0.49
At3g47460 [BD] KOG0933 Structural maintenance of chromosome prot... 35 0.49
At3g44790 [DR] KOG1987 Speckle-type POZ protein SPOP and related... 35 0.49
At2g31970 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/S... 35 0.49
At1g79830 [K] KOG4673 Transcription factor TMF TATA element modu... 35 0.49
At1g03830 [R] KOG2037 Guanylate-binding protein 35 0.49
YLR045c [Z] KOG1820 Microtubule-associated protein 34 0.64
Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein 34 0.64
Hs8923699 [S] KOG4725 Uncharacterized conserved protein 34 0.64
Hs7661992 [KRT] KOG4572 Predicted DNA-binding transcription fact... 34 0.64
Hs6912568 [DK] KOG4333 Nuclear DEAF-1 related transcriptional re... 34 0.64
Hs5453758 [Z] KOG1702 Nebulin repeat protein 34 0.64
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 34 0.64
Hs4758956 [TZ] KOG3632 Peripheral benzodiazepine receptor PRAX-1 34 0.64
Hs4505877 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prote... 34 0.64
Hs4503169 [K] KOG0963 Transcription factor/CCAAT displacement pr... 34 0.64
Hs22056365 [S] KOG4725 Uncharacterized conserved protein 34 0.64
Hs22045440 [T] KOG0612 Rho-associated coiled-coil containing pro... 34 0.64
Hs21735417 [U] KOG0999 Microtubule-associated protein Bicaudal-D 34 0.64
Hs20540694 [U] KOG0999 Microtubule-associated protein Bicaudal-D 34 0.64
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 34 0.64
Hs20485874 [S] KOG4725 Uncharacterized conserved protein 34 0.64
Hs17978507 [Z] KOG0161 Myosin class II heavy chain 34 0.64
Hs14720884 [R] KOG0504 FOG: Ankyrin repeat 34 0.64
CE27133 [Z] KOG0161 Myosin class II heavy chain 34 0.64
CE08332 [L] KOG0250 DNA repair protein RAD18 (SMC family protein) 34 0.64
CE00373 [O] KOG2177 Predicted E3 ubiquitin ligase 34 0.64
At3g20760 [S] KOG2866 Uncharacterized conserved protein 34 0.64
At1g73960 [K] KOG1932 TATA binding protein associated factor 34 0.64
SPCC364.04c [K] KOG0963 Transcription factor/CCAAT displacement ... 34 0.84
SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 34 0.84
Hs8922940 [Z] KOG1850 Myosin-like coiled-coil protein 34 0.84
Hs14772793 [Z] KOG0161 Myosin class II heavy chain 34 0.84
Hs14149971 [R] KOG0504 FOG: Ankyrin repeat 34 0.84
Hs11321579 [Z] KOG0161 Myosin class II heavy chain 34 0.84
CE23997 [Z] KOG3595 Dyneins heavy chain 34 0.84
CE20196 [Z] KOG0161 Myosin class II heavy chain 34 0.84
CE15865 [R] KOG2501 Thioredoxin nucleoredoxin and related proteins 34 0.84
CE10260 [U] KOG1655 Protein involved in vacuolar protein sorting 34 0.84
At2g22610 [Z] KOG0239 Kinesin (KAR3 subfamily) 34 0.84
7299993 [Z] KOG1003 Actin filament-coating protein tropomyosin 34 0.84
7295428 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin deg... 34 0.84
7293607 [DK] KOG4466 Component of histone deacetylase complex (b... 34 0.84
7291239 [U] KOG0993 Rab5 GTPase effector Rabaptin-5 34 0.84
7290766 [K] KOG4673 Transcription factor TMF TATA element modula... 34 0.84
Hs7662062_2 [U] KOG0864 Ran-binding protein RANBP1 and related R... 34 0.84
7292701_2 [S] KOG4415 Uncharacterized conserved protein 34 0.84
YJL074c [D] KOG0964 Structural maintenance of chromosome protein... 33 1.1
Hs9055284 [Z] KOG0160 Myosin class V heavy chain 33 1.1
Hs4506467 [R] KOG3529 Radixin moesin and related proteins of the... 33 1.1
Hs4502443 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prote... 33 1.1
Hs16507950 [Z] KOG2685 Cystoskeletal protein Tektin 33 1.1
Hs14735371 [S] KOG4725 Uncharacterized conserved protein 33 1.1
Hs13899237 [D] KOG4438 Centromere-associated protein NUF2 33 1.1
Hs11342676 [Z] KOG3565 Cdc42-interacting protein CIP4 33 1.1
CE21053 [U] KOG0946 ER-Golgi vesicle-tethering protein p115 33 1.1
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 33 1.1
At3g58430 [DR] KOG1987 Speckle-type POZ protein SPOP and related... 33 1.1
At1g70460 [T] KOG1187 Serine/threonine protein kinase 33 1.1
7301970 [V] KOG2392 Serpin 33 1.1
7296430 [TV] KOG4297 C-type lectin 33 1.1
Hs22045770_1 [R] KOG0504 FOG: Ankyrin repeat 33 1.1
7297853_1 [S] KOG3528 FOG: PDZ domain 33 1.1
SPAC26F1.09 [R] KOG1102 Rab6 GTPase activator GAPCenA and relate... 33 1.4
Hs7705861 [B] KOG1973 Chromatin remodeling protein contains PHD ... 33 1.4
Hs7661774 [U] KOG4442 Clathrin coat binding protein/Huntingtin i... 33 1.4
Hs7304923 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI lar... 33 1.4
Hs21553341 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prot... 33 1.4
ECU11g1420 [O] KOG1051 Chaperone HSP104 and related ATP-dependen... 33 1.4
CE21051 [S] KOG4744 Uncharacterized conserved protein 33 1.4
CE09197 [Z] KOG0161 Myosin class II heavy chain 33 1.4
At2g27170 [D] KOG0964 Structural maintenance of chromosome prote... 33 1.4
7303132 [BD] KOG0933 Structural maintenance of chromosome protei... 33 1.4
7300685 [T] KOG4370 Ral-GTPase effector RLIP76 33 1.4
YDR320c_1 [R] KOG1124 FOG: TPR repeat 33 1.4
Hs18573626_1 [R] KOG0504 FOG: Ankyrin repeat 33 1.4
YPR141c [Z] KOG0239 Kinesin (KAR3 subfamily) 33 1.9
YOL145c [P] KOG2002 TPR-containing nuclear phosphoprotein that r... 33 1.9
YKL114c [L] KOG3997 Major apurinic/apyrimidinic endonuclease/3'-... 33 1.9
SPCC576.13 [S] KOG4776 Uncharacterized conserved protein BCNT 33 1.9
SPBC146.03c [BD] KOG0996 Structural maintenance of chromosome pr... 33 1.9
Hs4827054 [O] KOG1868 Ubiquitin C-terminal hydrolase 33 1.9
Hs4507649 [Z] KOG1003 Actin filament-coating protein tropomyosin 33 1.9
Hs22058210 [W] KOG1574 Predicted cell growth/differentiation reg... 33 1.9
Hs22052011 [O] KOG2177 Predicted E3 ubiquitin ligase 33 1.9
Hs13259510 [DZ] KOG0971 Microtubule-associated protein dynactin ... 33 1.9
Hs13259508 [DZ] KOG0971 Microtubule-associated protein dynactin ... 33 1.9
CE25102 [B] KOG4364 Chromatin assembly factor-I 33 1.9
CE12324 [Z] KOG4280 Kinesin-like protein 33 1.9
CE03665 [Z] KOG0161 Myosin class II heavy chain 33 1.9
At5g61460 [L] KOG0250 DNA repair protein RAD18 (SMC family protein) 33 1.9
At5g07660 [L] KOG0250 DNA repair protein RAD18 (SMC family protein) 33 1.9
YMR136w [K] KOG1601 GATA-4/5/6 transcription factors 32 2.4
Hs22044126 [S] KOG4687 Uncharacterized coiled-coil protein 32 2.4
Hs18378735 [ZR] KOG4568 Cytoskeleton-associated protein and rela... 32 2.4
Hs14773804 [DZ] KOG0982 Centrosomal protein Nuf 32 2.4
ECU01g1160 [BD] KOG0933 Structural maintenance of chromosome pro... 32 2.4
CE28688 [T] KOG1215 Low-density lipoprotein receptors containing... 32 2.4
CE18390 [K] KOG3119 Basic region leucine zipper transcription fa... 32 2.4
CE16096 [T] KOG2265 Nuclear distribution protein NUDC 32 2.4
CE10372 [Z] KOG1425 Microfibrillar-associated protein MFAP1 32 2.4
CE07351 [S] KOG3758 Uncharacterized conserved protein 32 2.4
CE06626 [DZ] KOG0971 Microtubule-associated protein dynactin DCT... 32 2.4
CE03491 [ZR] KOG4568 Cytoskeleton-associated protein and related... 32 2.4
CE02914 [S] KOG2885 Uncharacterized conserved protein 32 2.4
At4g24580 [T] KOG4271 Rho-GTPase activating protein 32 2.4
At3g54670 [D] KOG0018 Structural maintenance of chromosome prote... 32 2.4
At2g36070 [U] KOG2580 Mitochondrial import inner membrane transl... 32 2.4
At2g02160 [S] KOG4791 Uncharacterized conserved protein 32 2.4
7304074 [DZU] KOG2655 Septin family protein (P-loop GTPase) 32 2.4
7295270 [D] KOG1126 DNA-binding cell division cycle control protein 32 2.4
CE12968_2 [Z] KOG0244 Kinesin-like protein 32 2.4
YKL095w [S] KOG2989 Uncharacterized conserved protein 32 3.2
YJR045c [O] KOG0102 Molecular chaperones mortalin/PBP74/GRP75 HS... 32 3.2
SPBC21D10.10 [BK] KOG1472 Histone acetyltransferase SAGA/ADA cat... 32 3.2
SPAC4F10.11 [DZU] KOG2655 Septin family protein (P-loop GTPase) 32 3.2
SPAC27D7.14c [P] KOG2002 TPR-containing nuclear phosphoprotein t... 32 3.2
Hs6005938 [NTZ] KOG4286 Dystrophin-like protein 32 3.2
Hs4758650 [Z] KOG0240 Kinesin (SMY1 subfamily) 32 3.2
Hs22065277 [Z] KOG4807 F-actin binding protein regulates actin c... 32 3.2
Hs18563233 [Z] KOG1850 Myosin-like coiled-coil protein 32 3.2
Hs18557432 [S] KOG4036 Uncharacterized conserved protein 32 3.2
CE25014 [R] KOG2010 Double stranded RNA binding protein 32 3.2
CE22238 [S] KOG0992 Uncharacterized conserved protein 32 3.2
CE19212 [S] KOG4643 Uncharacterized coiled-coil protein 32 3.2
CE14217 [S] KOG4360 Uncharacterized coiled coil protein 32 3.2
CE03287 [BD] KOG0996 Structural maintenance of chromosome protei... 32 3.2
At5g57120 [Y] KOG2992 Nucleolar GTPase/ATPase p130 32 3.2
7299439 [K] KOG3779 Homeobox transcription factor prospero 32 3.2
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 32 3.2
7293243 [D] KOG0964 Structural maintenance of chromosome protein... 32 3.2
YLR383w [L] KOG0250 DNA repair protein RAD18 (SMC family protein) 32 4.2
YBR245c [K] KOG0385 Chromatin remodeling complex WSTF-ISWI small... 32 4.2
SPAC25G10.07c [Z] KOG0243 Kinesin-like protein 32 4.2
SPAC10F6.09c [D] KOG0964 Structural maintenance of chromosome pr... 32 4.2
Hs5730037 [U] KOG3745 Exocyst subunit - Sec10p 32 4.2
Hs5729812 [K] KOG4796 RNA polymerase II elongation factor 32 4.2
Hs5032013 [Z] KOG0247 Kinesin-like protein 32 4.2
Hs5031831 [Z] KOG1840 Kinesin light chain 32 4.2
Hs4502695 [DZU] KOG2655 Septin family protein (P-loop GTPase) 32 4.2
Hs22062766 [DZU] KOG2655 Septin family protein (P-loop GTPase) 32 4.2
Hs20469207 [O] KOG3607 Meltrins fertilins and related Zn-depende... 32 4.2
Hs19924131 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/... 32 4.2
Hs19924129 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/... 32 4.2
Hs18641345 [O] KOG2177 Predicted E3 ubiquitin ligase 32 4.2
Hs18087807 [O] KOG2177 Predicted E3 ubiquitin ligase 32 4.2
Hs16554453 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin ... 32 4.2
Hs13435145 [R] KOG3647 Predicted coiled-coil protein 32 4.2
Hs13376757 [R] KOG1729 FYVE finger containing protein 32 4.2
CE12204 [Z] KOG0161 Myosin class II heavy chain 32 4.2
CE06253 [Z] KOG0161 Myosin class II heavy chain 32 4.2
At4g39050 [Z] KOG0242 Kinesin-like protein 32 4.2
At3g45850 [Z] KOG0243 Kinesin-like protein 32 4.2
At1g14910 [TU] KOG0251 Clathrin assembly protein AP180 and relat... 32 4.2
7303914 [T] KOG0694 Serine/threonine protein kinase 32 4.2
7301276 [R] KOG2030 Predicted RNA-binding protein 32 4.2
7299195 [D] KOG2398 Predicted proline-serine-threonine phosphata... 32 4.2
CE04187_1 [I] KOG1202 Animal-type fatty acid synthase and relate... 32 4.2
YGR092w [R] KOG0605 NDR and related serine/threonine kinases 31 5.4
YEL061c [Z] KOG0243 Kinesin-like protein 31 5.4
YBR172c [R] KOG1862 GYF domain containing proteins 31 5.4
SPAC4A8.05c [Z] KOG0161 Myosin class II heavy chain 31 5.4
SPAC3C7.12 [ZR] KOG4568 Cytoskeleton-associated protein and rela... 31 5.4
SPAC1687.10 [DZ] KOG4302 Microtubule-associated protein essentia... 31 5.4
Hs4758648 [Z] KOG0240 Kinesin (SMY1 subfamily) 31 5.4
Hs20536150 [O] KOG0181 20S proteasome regulatory subunit alpha t... 31 5.4
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 31 5.4
Hs13375848 [L] KOG0250 DNA repair protein RAD18 (SMC family prot... 31 5.4
CE29497 [D] KOG0018 Structural maintenance of chromosome protein... 31 5.4
CE29060 [Z] KOG1003 Actin filament-coating protein tropomyosin 31 5.4
CE28782 [Z] KOG1003 Actin filament-coating protein tropomyosin 31 5.4
CE27102 [TU] KOG0078 GTP-binding protein SEC4 small G protein su... 31 5.4
CE26945 [Z] KOG0240 Kinesin (SMY1 subfamily) 31 5.4
CE02790 [T] KOG0976 Rho/Rac1-interacting serine/threonine kinase... 31 5.4
At5g61980 [T] KOG0521 Putative GTPase activating proteins (GAPs) 31 5.4
At4g28470 [O] KOG2005 26S proteasome regulatory complex subunit ... 31 5.4
At3g44050 [Z] KOG4280 Kinesin-like protein 31 5.4
At3g43210 [Z] KOG0242 Kinesin-like protein 31 5.4
At1g75310 [R] KOG0431 Auxilin-like protein and related proteins ... 31 5.4
7300103 [Z] KOG0161 Myosin class II heavy chain 31 5.4
7300102 [Z] KOG0161 Myosin class II heavy chain 31 5.4
7300010 [U] KOG2307 Low density lipoprotein receptor 31 5.4
7296991 [DY] KOG0977 Nuclear envelope protein lamin intermediate... 31 5.4
7292248 [T] KOG1945 Protein phosphatase 1 binding protein spinop... 31 5.4
YBR289w [BK] KOG1649 SWI-SNF chromatin remodeling complex Snf5 s... 31 7.1
SPBC29A10.10c [A] KOG1801 tRNA-splicing endonuclease positive ef... 31 7.1
SPBC12C2.05c [Z] KOG3565 Cdc42-interacting protein CIP4 31 7.1
Hs4505993 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prote... 31 7.1
Hs21389431 [R] KOG0619 FOG: Leucine rich repeat 31 7.1
Hs20539050 [Z] KOG1003 Actin filament-coating protein tropomyosin 31 7.1
Hs16519561 [O] KOG2177 Predicted E3 ubiquitin ligase 31 7.1
Hs13376429 [S] KOG4036 Uncharacterized conserved protein 31 7.1
Hs11497601 [O] KOG3607 Meltrins fertilins and related Zn-depende... 31 7.1
ECU07g1500 [P] KOG0208 Cation transport ATPase 31 7.1
CE28364 [K] KOG3119 Basic region leucine zipper transcription fa... 31 7.1
CE26870 [G] KOG3635 Phosphorylase kinase 31 7.1
CE26813 [K] KOG3095 Transcription initiation factor IIE beta sub... 31 7.1
CE04694 [R] KOG2226 Proteins containing regions of low-complexity 31 7.1
At4g11420 [J] KOG2072 Translation initiation factor 3 subunit a ... 31 7.1
At3g54870 [Z] KOG0240 Kinesin (SMY1 subfamily) 31 7.1
At1g65470 [B] KOG4364 Chromatin assembly factor-I 31 7.1
7301120 [L] KOG0250 DNA repair protein RAD18 (SMC family protein) 31 7.1
7300366 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/VAM... 31 7.1
7298502 [R] KOG4722 Zn-finger protein 31 7.1
7296462 [BDL] KOG0979 Structural maintenance of chromosome prote... 31 7.1
7294041 [S] KOG1181 FOG: Low-complexity 31 7.1
7291833 [A] KOG0127 Nucleolar protein fibrillarin NOP77 (RRM sup... 31 7.1
7291408 [R] KOG0249 LAR-interacting protein and related proteins 31 7.1
YHR158c [R] KOG0379 Kelch repeat-containing proteins 30 9.3
SPCP25A2.02c [KL] KOG0387 Transcription-coupled repair protein C... 30 9.3
SPAPJ760.02c [Z] KOG3655 Drebrins and related actin binding prot... 30 9.3
HsM19923376 [T] KOG3520 Predicted guanine nucleotide exchange fa... 30 9.3
HsM17933492 [T] KOG3520 Predicted guanine nucleotide exchange fa... 30 9.3
Hs8923604 [U] KOG0811 SNARE protein PEP12/VAM3/Syntaxin 7/Syntax... 30 9.3
Hs7706314 [TO] KOG2606 OTU (ovarian tumor)-like cysteine protease 30 9.3
Hs7304919 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI lar... 30 9.3
Hs6382071 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous 30 9.3
Hs6005826 [TUZ] KOG2856 Adaptor protein PACSIN 30 9.3
Hs5803003 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous 30 9.3
Hs5031959 [O] KOG0885 Peptidyl-prolyl cis-trans isomerase 30 9.3
Hs4826908 [T] KOG4637 Adaptor for phosphoinositide 3-kinase 30 9.3
Hs4557565 [KL] KOG0387 Transcription-coupled repair protein CSB/... 30 9.3
Hs4507651 [Z] KOG1003 Actin filament-coating protein tropomyosin 30 9.3
Hs22046914 [T] KOG1997 PH domain-containing protein 30 9.3
Hs21493031 [T] KOG3520 Predicted guanine nucleotide exchange factor 30 9.3
Hs21493029 [T] KOG3520 Predicted guanine nucleotide exchange factor 30 9.3
Hs21493026 [T] KOG3520 Predicted guanine nucleotide exchange factor 30 9.3
Hs20484473 [S] KOG4725 Uncharacterized conserved protein 30 9.3
Hs16162192 [TO] KOG2606 OTU (ovarian tumor)-like cysteine protease 30 9.3
Hs16160857 [Z] KOG0160 Myosin class V heavy chain 30 9.3
Hs15451892 [J] KOG1144 Translation initiation factor 5B (eIF-5B) 30 9.3
Hs15147252 [T] KOG4270 GTPase-activator protein 30 9.3
Hs15011908 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prot... 30 9.3
Hs10835119 [Z] KOG0160 Myosin class V heavy chain 30 9.3
ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing pro... 30 9.3
CE27954 [Z] KOG0613 Projectin/twitchin and related proteins 30 9.3
CE26143 [Z] KOG4280 Kinesin-like protein 30 9.3
CE19073 [U] KOG2528 Sorting nexin SNX9/SH3PX1 and related proteins 30 9.3
CE17314 [K] KOG1015 Transcription regulator XNP/ATRX DEAD-box su... 30 9.3
CE05711 [Z] KOG0035 Ca2+-binding actin-bundling protein (actinin... 30 9.3
At5g50840 [Z] KOG1850 Myosin-like coiled-coil protein 30 9.3
At5g38840 [R] KOG1881 Anion exchanger adaptor protein Kanadaptin... 30 9.3
At4g21270 [Z] KOG0239 Kinesin (KAR3 subfamily) 30 9.3
At4g11080 [R] KOG0381 HMG box-containing protein 30 9.3
At4g05190 [Z] KOG0239 Kinesin (KAR3 subfamily) 30 9.3
At3g54170 [A] KOG2991 Splicing regulator 30 9.3
At3g49750 [R] KOG0619 FOG: Leucine rich repeat 30 9.3
At2g25130 [S] KOG0167 FOG: Armadillo/beta-catenin-like repeats 30 9.3
At1g11870 [J] KOG2509 Seryl-tRNA synthetase 30 9.3
7303557 [R] KOG1808 AAA ATPase containing von Willebrand factor ... 30 9.3
7294571 [S] KOG3443 Uncharacterized conserved protein 30 9.3
7294416 [TZ] KOG1923 Rac1 GTPase effector FRL 30 9.3
At3g18730_1 [R] KOG1124 FOG: TPR repeat 30 9.3
>YNL243w [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-interacting
protein Hip1
Length = 968
Score = 367 bits (942), Expect = e-101
Identities = 266/774 (34%), Positives = 371/774 (47%), Gaps = 168/774 (21%)
Query: 9 MSREEQTLEKSIKKALSGGDVAPKRKHVRACIVYTWDHKSSKTFFNLLKLQPYATDELQL 68
MSR + L+K++KKA S + APKRKHVRACIVYTWDH+SSK F LK P A DE+QL
Sbjct: 1 MSRIDSDLQKALKKACSVEETAPKRKHVRACIVYTWDHQSSKAVFTTLKTLPLANDEVQL 60
Query: 69 FKALVLLHKVLQEGHPSALVEGIRNIDWIESLSRIFSVDSDDGSKYGSSRMRYIGDEYAK 128
FK L++LHK++QEGHPSAL E IR+ DWI SL R+ S G Y+K
Sbjct: 61 FKMLIVLHKIIQEGHPSALAEAIRDRDWIRSLGRVHSG----------------GSSYSK 104
Query: 129 AIGEYVFFLVEKLQFHKSHKGF-NGIFEYEEYVSLVSVSDPNEGYETVLDLMNLEDVADN 187
I EYV +LV KL FH H+GF NG FEYEEYVSLVSVSDP+EGYET+LDLM+L+D D
Sbjct: 105 LIREYVRYLVLKLDFHAHHRGFNNGTFEYEEYVSLVSVSDPDEGYETILDLMSLQDSLDE 164
Query: 188 LQKLIFAGISNRKSGFGSFSSGLDCRGAVLIPLVSETYGIFKFVTSMMKALYKQMGDYD- 246
++IFA I + + +C+ + LIPL++E+YGI+KF+TSM++A+++Q+ D +
Sbjct: 165 FSQIIFASIQSER-------RNTECKISALIPLIAESYGIYKFITSMLRAMHRQLNDAEG 217
Query: 247 --ALSGLFDRYTEQCARLNEFYFDCNTVQPLKNLITIPTLPSDPMSRIIXXXXXXXXXXX 304
AL L +RY Q ARL EFY DC++V+ L L+TIP LP D +
Sbjct: 218 DAALQPLKERYELQHARLFEFYADCSSVKYLTTLVTIPKLPVDAPDVFL--------IND 269
Query: 305 XXXXXXXXXXXXXXXXXXXRENLRDPSPVHEAPPVARPAEVRSLSQPAAPVVPIATGVVM 364
R R P+P PPV +++PA P++
Sbjct: 270 VDESKEIKFKKREPSVTPARTPARTPTP---TPPV--------VAEPAISPRPVSQRTT- 317
Query: 365 PVVTGYSQPPLQVVPTGAEFWSIPSTSAPTRSVV------ASHDDXXXXXXXXXXXXXXX 418
TGY LQ +PTGA + T+ R+ + D
Sbjct: 318 STPTGY----LQTMPTGATTGMMIPTATGARNAIFPQATAQMQPDFWANQQAQFANEQNR 373
Query: 419 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXMEKEALIQQKTASLQNDIMSFKNQYERDQVM 478
M L QQ QND+++ NQYE+DQ +
Sbjct: 374 LEQERVQQLQQQQAQQELFQQQLQKAQQDMMNMQLQQQN--QHQNDLIALTNQYEKDQAL 431
Query: 479 LEQYDKRVQKLESEL----------------------ESVKEFKEKYQSLAKLYSQLRQE 516
L+QYD+RVQ+LESE+ + + ++ KY+SLAKLYSQLRQE
Sbjct: 432 LQQYDQRVQQLESEITTMDSTASKQLANKDEQLTALQDQLDVWERKYESLAKLYSQLRQE 491
Query: 517 HLNILKKMKKTQDDLAEAESEVK-------KLKSSALSNVGI------------RNNNKG 557
HLN+L + KK Q + A+ ++ KLK L + R+ N
Sbjct: 492 HLNLLPRFKKLQLKVNSAQESIQKKEQLEHKLKQKDLQMAELVKDRDRARLELERSINNA 551
Query: 558 ESEREEA--------KDRSGMILKSLVESSIKSLQDPIASLD------------------ 591
E++ A +D+ IL +++ES I ++Q+ + +LD
Sbjct: 552 EADSAAATAAAETMTQDKMNPILDAILESGINTIQESVYNLDSPLSWSGPLTPPTFLLSL 611
Query: 592 -------VSDLATDLSNAFIDG--------------DINT------------IVNILP-- 616
++ AT +N +DG D +T V LP
Sbjct: 612 LESTSENATEFATSFNNLIVDGLAHGDQTEVIHCVSDFSTSMATLVTNSKAYAVTTLPQE 671
Query: 617 ---EFVSLLLRCPQEMQTIAEDF----LRCLSSAKQTDSVINANIAFQEKLKRL 663
+ ++L+ RC +E Q ED L + ++TD VINAN+ QEKL+ L
Sbjct: 672 QSDQILTLVKRCAREAQYFFEDLMSENLNQVGDEEKTDIVINANVDMQEKLQEL 725
>SPAC688.11 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-interacting
protein Hip1
Length = 1092
Score = 283 bits (723), Expect = 8e-76
Identities = 194/650 (29%), Positives = 301/650 (45%), Gaps = 125/650 (19%)
Query: 11 REEQTLEKSIKKALSGGDVAPKRKHVRACIVYTWDHKSSKTFFNLLKLQPYATDELQLFK 70
+ + +L S++KA S + APKRKHVR+CI++TWDH +++ F+ +K+QP +E+Q FK
Sbjct: 2 QSDASLMTSVRKATSIDETAPKRKHVRSCIIFTWDHHTARPFWTAIKVQPLLANEVQTFK 61
Query: 71 ALVLLHKVLQEGHPSALVEGIRNIDWIESLSRIFSVDSDDGSKYGSSRMRYIGDEYAKAI 130
AL+ +H+VLQEGH SALV+ W+++ R + +S Y+ I
Sbjct: 62 ALITIHRVLQEGHKSALVDSQSEKGWLKTCERQYDGESSPKG-------------YSDLI 108
Query: 131 GEYVFFLVEKLQFHKSHKGFNGIFEYEEYVSLVSVSDPNEGYETVLDLMNLEDVADNLQK 190
+YV +L++KL FH H FNG FEY+EY+SL V DPNEGYETV D+MNL+D D QK
Sbjct: 109 RDYVDYLLDKLSFHAQHPEFNGTFEYKEYISLRQVDDPNEGYETVYDMMNLQDHIDEFQK 168
Query: 191 LIFAGISNRKSGFGSFSSGLDCRGAVLIPLVSETYGIFKFVTSMMKALYKQMGDYDALSG 250
+F+ S+ +CR A L+PLV E+YGI++F+TSM++ALY + + L
Sbjct: 169 QLFSNFKR--------SNKNECRIAALVPLVQESYGIYRFLTSMLRALYSTVDAPETLEP 220
Query: 251 LFDRYTEQCARLNEFYFDCNTVQPLKNLITIPTLPSDPMSRIIXXXXXXXXXXXXXXXXX 310
L RY Q RL +FY DC+ ++ L +LI++P LP DP
Sbjct: 221 LKHRYKSQHHRLRQFYADCSNLRYLTSLISVPRLPHDP---------------------- 258
Query: 311 XXXXXXXXXXXXXRENLRDPSPVHEAPPVARPAEVRSLSQPAAPVVPIATGV-------- 362
+L + + P RPA + A+ + P TG
Sbjct: 259 --------------PDLEGDDNIPDLP--KRPASIAPQPTGASTIAPQPTGTSPSPPVEM 302
Query: 363 ----VMPVVTGYSQP-PLQVVPTGAEFWSIPS----TSAPTRSVVASHDDXXXXXXXXXX 413
+ YS+P P+Q +FWS P+ +A + A+
Sbjct: 303 NFPDTSDITPAYSEPEPIQ------DFWSDPTLDQQLAAQQAAQQAAQQQAELAAQQAAA 356
Query: 414 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMEKEALIQQ-------------KTAS 460
E++ + Q+ + A
Sbjct: 357 QQAQLAAQQAAEMERQRMAAQQHQQALEAIQMAQAEQQRIAQEQLAQQQFQMQTQGQLAE 416
Query: 461 LQNDIMSFKNQYERDQVMLEQYDKRVQKLESEL------------------ESVKE---- 498
L+ +++ + Q E+ V+L QYD RV+ LE+EL ES+K
Sbjct: 417 LEQQLLATRGQLEQSNVLLNQYDARVRTLENELSQAGVNLQEQIHQNDDLIESLKNQILT 476
Query: 499 FKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKK-------LKSSALSNVGI 551
+K KY++LAKLY+QLRQEHL++L K K+ Q + A+ + K +K+ L +
Sbjct: 477 WKNKYEALAKLYTQLRQEHLDLLSKYKQIQLKASSAQEAIDKKEKMEREMKNKNLELADM 536
Query: 552 RNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSN 601
E RS + E ++ LQ+ ASL+ + ++++SN
Sbjct: 537 ILERDRARHELETMHRSQRDKQESTERELRLLQEKAASLE-RNKSSEVSN 585
>Hs14760485 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-interacting
protein Hip1
Length = 1068
Score = 91.7 bits (226), Expect = 3e-18
Identities = 77/294 (26%), Positives = 130/294 (44%), Gaps = 25/294 (8%)
Query: 2 ILQVRTGMSRE------EQTLEKSIKKALSGGDVAPKRKHVRACIVYTWDHKSSKTFFNL 55
+L R G S E ++T SI KA++ + K KH R I+ T K + TF++
Sbjct: 11 VLSRRPGHSLEAEREQFDKTQAISISKAINTQEAPVKEKHARRIILGTHHEKGAFTFWSY 70
Query: 56 LKLQPYATDELQLFKALVLLHKVLQEGHPSALVEGIRNIDWIESLSRIFSVDSDDGSKYG 115
P + + +K +LHKVL++GHP+ L R S + G +G
Sbjct: 71 AIGLPLPSSSILSWKFCHVLHKVLRDGHPNVL----------HDCQRYRSNIREIGDLWG 120
Query: 116 SSRMRYIGDEYAKAIGEYVFFLVEKLQFHKSHKGF-NGIFEYEEYVSLVSVSDPNEGYET 174
++ D Y + + Y L+ K+ FH H F G+ +E + + +D N ++
Sbjct: 121 -----HLHDRYGQLVNVYTKLLLTKISFHLKHPQFPAGLEVTDEVLEKAAGTDVNNIFQL 175
Query: 175 VLDLMNLEDVADNLQKLIFAGISNRKSGFGSFSSGLDCRGAVLIPLVSETYGIFKFVTSM 234
+++ + D L + +F + N SSG CR A LI ++ + ++ + +
Sbjct: 176 TVEMFDYMDCELKLSESVFRQL-NTAIAVSQMSSG-QCRLAPLIQVIQDCSHLYHYTVKL 233
Query: 235 MKALYKQMGDYDALSGLFDRYTEQCARLNEFYFDCNTVQPLKNLITIPTLPSDP 288
+ L+ + D L G DR+ EQ L F+ + + K LI IP LP P
Sbjct: 234 LFKLHSCL-PADTLQGHRDRFHEQFHSLRNFFRRASDMLYFKRLIQIPRLPEGP 286
Score = 32.0 bits (71), Expect = 3.2
Identities = 26/99 (26%), Positives = 53/99 (53%), Gaps = 9/99 (9%)
Query: 473 ERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLA 532
+RD + +E + V+ L SELE +K ++Y +A+L SQ+ + ++ K+ Q L
Sbjct: 351 DRD-LQIESLKREVEMLRSELEKIKLEAQRY--IAQLKSQVNALEGELEEQRKQKQKALV 407
Query: 533 EAES---EVKKLKSSALS---NVGIRNNNKGESEREEAK 565
+ E E+ +L+++ L + G+R + ++ EA+
Sbjct: 408 DNEQLRHELAQLRAAQLEGERSQGLREEAERKASATEAR 446
>7294543 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-interacting
protein Hip1
Length = 1087
Score = 78.2 bits (191), Expect = 4e-14
Identities = 66/241 (27%), Positives = 110/241 (45%), Gaps = 21/241 (8%)
Query: 47 KSSKTFFNLLKLQPYATDELQLFKALVLLHKVLQEGHPSALVEGIRNIDWIESLSRIFSV 106
K +KTF+ ++ QP +K LLHKVL+EGH SA+ + I + +++ +
Sbjct: 6 KEAKTFWMIISRQPLMQSRFTAWKFSHLLHKVLREGHESAIRHSQSHKKMILEVGKMWGL 65
Query: 107 DSDDGSKYGSSRMRYIGDEYAKAIGEYVFFLVEKLQFHKSHKGFNGIFEYEEYVSLVSVS 166
+ D+ I Y L KL FH ++ F G ++V
Sbjct: 66 ---------------LQDDIGCCIQAYSKLLATKLNFHDKNRMFPGTLNISFTELFIAVD 110
Query: 167 -DPNEGYETVLDLMN-LEDVADNLQKLIFAGISNRKSGFGSFSSGLDCRGAVLIPLVSET 224
D N ++ +++ + LED+ LQ IF+ S K S + CR A ++ L+ ++
Sbjct: 111 RDLNYCFQLCVEIFDYLEDII-ALQLTIFS--SMEKYRMSSMTPQGQCRLAPIVCLIQDS 167
Query: 225 YGIFKFVTSMMKALYKQMGDYDALSGLFDRYTEQCARLNEFYFDCNTVQPLKNLITIPTL 284
++ +M L+ + YD +SG DR+ +L FY + +Q K+LITIP L
Sbjct: 168 NALYDLSVRLMFKLHDGV-PYDVVSGHRDRFHGLFLKLKSFYNNVRPLQYFKDLITIPEL 226
Query: 285 P 285
P
Sbjct: 227 P 227
Score = 50.4 bits (119), Expect = 9e-06
Identities = 55/224 (24%), Positives = 104/224 (45%), Gaps = 24/224 (10%)
Query: 454 IQQKTASLQNDIM-------SFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSL 506
+QQ L ND++ +F+ Q + ++ L Q +QK E E K EK+ L
Sbjct: 320 LQQNNTVLSNDLVLAREMCATFRMQNDDLEMQLNQNPILLQKAMEEEEKHKLSSEKFNKL 379
Query: 507 AKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESE-REEAK 565
LY+++R EH+ +L++ Q D ++ ++ K++ S L N + + E K
Sbjct: 380 KTLYTKIRDEHIQLLRE----QSDCNKSLNKEKQVNSQLLLETKELTNEISKIKVNVEEK 435
Query: 566 DRSGMILKSLVESSIKSLQDPIASLDV--SDLATDLSNAFIDGDINTIVNILPEFVSLLL 623
+++ +IL+ +E ++ IA L+ +++ + +I + +I+ +L L
Sbjct: 436 EKTNLILQKQIEEH----KEKIAHLEAVKNEMKEKFDDVVKQKEIQEL-DIISTSENLRL 490
Query: 624 RC--PQEMQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKRLGE 665
C +E+ D L LS+A +S INA EK+ + E
Sbjct: 491 NCLKVEELNGNLNDTLEKLSNA---ESQINAKTEDIEKMLKAFE 531
>CE29640 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-interacting
protein Hip1
Length = 921
Score = 77.8 bits (190), Expect = 5e-14
Identities = 64/269 (23%), Positives = 120/269 (43%), Gaps = 17/269 (6%)
Query: 18 KSIKKALSGGDVAPKRKHVRACIVYTWDHKSSKTFFNLLKLQPYATDELQLFKALVLLHK 77
++++KA++ +V K KH R IV T KSS F++ + + +K L+HK
Sbjct: 17 EAVQKAITKNEVPLKPKHARTIIVGTHKEKSSGIFWHTVGRIQLEKHPVLTWKFCHLVHK 76
Query: 78 VLQEGHPSALVEGIRNIDWIESLSRIFSVDSDDGSKYGSSRMRYIGDEYAKAIGEYVFFL 137
+L++GH E R ++ LS+ + + G Y I Y L
Sbjct: 77 LLRDGHRKVPEETYRYVNRFTQLSQFWKHLNTSG--------------YGPCIESYCKLL 122
Query: 138 VEKLQFHKSHKGFNGIFEYEEYVSLVSVSDPNEGYETVLDLMNLEDVADNLQKLIFAGIS 197
+++ FH + G + + D + +E +D+++ D LQ ++ ++
Sbjct: 123 HDRVTFHNKYPVVPGKLDLNDSQLKTLEGDLDNMFEMTIDMLDQMDALLVLQDRVYEMMN 182
Query: 198 NRKSGFGSFSSGLDCRGAVLIPLVSETYGIFKFVTSMMKALYKQMGDYDALSGLFDRYTE 257
+ + + S C + LI + +T + ++ M+ L+ Q+ DAL G R+
Sbjct: 183 SLR--WNSLIPQGQCMLSPLIIAILDTSKFYDYLVKMIFKLHSQVPP-DALEGHRSRFRT 239
Query: 258 QCARLNEFYFDCNTVQPLKNLITIPTLPS 286
R +FY + + +Q K L++IPTLPS
Sbjct: 240 IFERTKKFYEESSNLQYFKYLVSIPTLPS 268
>CE00540 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-interacting
protein Hip1
Length = 927
Score = 77.8 bits (190), Expect = 5e-14
Identities = 64/269 (23%), Positives = 120/269 (43%), Gaps = 17/269 (6%)
Query: 18 KSIKKALSGGDVAPKRKHVRACIVYTWDHKSSKTFFNLLKLQPYATDELQLFKALVLLHK 77
++++KA++ +V K KH R IV T KSS F++ + + +K L+HK
Sbjct: 17 EAVQKAITKNEVPLKPKHARTIIVGTHKEKSSGIFWHTVGRIQLEKHPVLTWKFCHLVHK 76
Query: 78 VLQEGHPSALVEGIRNIDWIESLSRIFSVDSDDGSKYGSSRMRYIGDEYAKAIGEYVFFL 137
+L++GH E R ++ LS+ + + G Y I Y L
Sbjct: 77 LLRDGHRKVPEETYRYVNRFTQLSQFWKHLNTSG--------------YGPCIESYCKLL 122
Query: 138 VEKLQFHKSHKGFNGIFEYEEYVSLVSVSDPNEGYETVLDLMNLEDVADNLQKLIFAGIS 197
+++ FH + G + + D + +E +D+++ D LQ ++ ++
Sbjct: 123 HDRVTFHNKYPVVPGKLDLNDSQLKTLEGDLDNMFEMTIDMLDQMDALLVLQDRVYEMMN 182
Query: 198 NRKSGFGSFSSGLDCRGAVLIPLVSETYGIFKFVTSMMKALYKQMGDYDALSGLFDRYTE 257
+ + + S C + LI + +T + ++ M+ L+ Q+ DAL G R+
Sbjct: 183 SLR--WNSLIPQGQCMLSPLIIAILDTSKFYDYLVKMIFKLHSQVPP-DALEGHRSRFRT 239
Query: 258 QCARLNEFYFDCNTVQPLKNLITIPTLPS 286
R +FY + + +Q K L++IPTLPS
Sbjct: 240 IFERTKKFYEESSNLQYFKYLVSIPTLPS 268
>CE17638 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-interacting
protein Hip1
Length = 362
Score = 67.0 bits (162), Expect = 9e-11
Identities = 60/272 (22%), Positives = 114/272 (41%), Gaps = 26/272 (9%)
Query: 18 KSIKKALSGGDVAPKRKHVRACIVYTWDHKSSKTFFNLLKLQPYATDELQLFKALVLLHK 77
++++KA++ + K KH+ ++ T KSS F++ +K + +K +L+HK
Sbjct: 12 QAVQKAITKDETPLKPKHLETILLGTHTEKSSAIFWSSVKKIKLENHPVLTWKFCLLVHK 71
Query: 78 VLQEGHPSALVEGIRNIDWIESLSRIFSVDSDDGSKYGSSRMRYIGDEYAKAIGEYVFFL 137
+L++GHP E RN L+ + D Y I Y L
Sbjct: 72 LLRDGHPVVPKEAYRNEKRFTQLALHWKDKRD----------------YGPCIDAYCKLL 115
Query: 138 VEKLQFHKSHKGFNGIFEYEEYVSLVSVSDPNEGYETVL----DLMNLEDVADNLQKLIF 193
+++ FH F G +VS + + +L D+M+ D Q+ ++
Sbjct: 116 HDRVIFHHKRPYFPG----NLFVSPLQLDTMGRDLSRMLRLTGDMMHQMDSLLAFQEKVY 171
Query: 194 AGISNRKSGFGSFSSGLDCRGAVLIPLVSETYGIFKFVTSMMKALYKQMGDYDALSGLFD 253
+SN + + C LI ++ +T+ F ++ MM L+ + ++ L G
Sbjct: 172 L-LSNSSPRWDPNTPQGQCLMLPLISVIMDTWPFFIYIVRMMYNLHSNVSPHE-LEGYRS 229
Query: 254 RYTEQCARLNEFYFDCNTVQPLKNLITIPTLP 285
R+ + +FY +C+ Q + + IPT P
Sbjct: 230 RFQTIFEKTKQFYEECSKHQYFRCFVQIPTFP 261
>Hs7427515 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-interacting
protein Hip1
Length = 914
Score = 58.9 bits (141), Expect = 2e-08
Identities = 38/169 (22%), Positives = 81/169 (47%), Gaps = 4/169 (2%)
Query: 121 YIGDEYAKAIGEYVFFLVEKLQFHKSHKGFNGIFEYEE-YVSLVSVSDPNEGYETVLDLM 179
++ + Y + Y+ L K+++H + F G + + + SD N ++ +++
Sbjct: 7 HLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMF 66
Query: 180 NLEDVADNLQKLIFAGISNRKSGFGSFSSGLDCRGAVLIPLVSETYGIFKFVTSMMKALY 239
+ + NL + +F + +S S ++ CR A LI ++ + ++ + ++ L+
Sbjct: 67 DYLECELNLFQTVFNSLDMSRSV--SVTAAGQCRLAPLIQVILDCSHLYDYTVKLLFKLH 124
Query: 240 KQMGDYDALSGLFDRYTEQCARLNEFYFDCNTVQPLKNLITIPTLPSDP 288
+ D L G DR+ EQ +L + ++ + +Q K LI IP LP +P
Sbjct: 125 SCL-PADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENP 172
Score = 34.7 bits (78), Expect = 0.49
Identities = 34/130 (26%), Positives = 63/130 (48%), Gaps = 15/130 (11%)
Query: 473 ERDQVMLEQYD-KRVQKLESELESVKEFKE-KYQSLAKLYSQLRQEHLNILKKMKKTQDD 530
E D++ ++ D ++ Q+ SE+E + E +Y L + YS+L Q H ++L+K +
Sbjct: 313 ELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQ 372
Query: 531 LAEA-------ESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSL 583
++ A E E K+L+ S L + + K + + E + LK + +S + L
Sbjct: 373 VSMARQAQVDLEREKKELEDS-LERISDQGQRKTQEQLEVLES-----LKQELATSQREL 426
Query: 584 QDPIASLDVS 593
Q SL+ S
Sbjct: 427 QVLQGSLETS 436
>CE08573 [S] KOG4787 Uncharacterized conserved protein
Length = 1577
Score = 48.5 bits (114), Expect = 3e-05
Identities = 51/227 (22%), Positives = 102/227 (44%), Gaps = 18/227 (7%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYD---KRVQKLESELESVKEFKEKYQS 505
E L++ K+ +L S + Q ER + + + + K +Q+LE++ ++VKEF+ KY+
Sbjct: 758 ELSELLESKSTTLVEKTRSLEEQEERSKKLRAETELLRKDMQELETDKKTVKEFEIKYKK 817
Query: 506 LAKLYSQLRQE-------HLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGE 558
L ++ R++ N L MKK +DD AE +KKL N K +
Sbjct: 818 LESIFETEREKMNGERNRSKNELAAMKKLKDD---AEEHLKKLSDDQKKNDAAWKIEKSK 874
Query: 559 SEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEF 618
E++ A + + + ++ S + Q+ I+ + S L S + ++ ++IL +
Sbjct: 875 LEKDIALLKKQLPDEHEMKESTATPQNSISG-ESSPLRRQDSEKMLVLELKKQISILEKR 933
Query: 619 V----SLLLRCPQEMQTIAEDFLRCLSSAKQTDSVINANIAFQEKLK 661
+ S L C + + + + ++ ++ V EKL+
Sbjct: 934 IADSNSSLEECKIQNAELRDQLAKVQANWEKDKEVFQHKTRKSEKLR 980
Score = 32.3 bits (72), Expect = 2.4
Identities = 25/126 (19%), Positives = 59/126 (45%), Gaps = 12/126 (9%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLA 507
ME+ ++ + LQ +I ++QY +++ E++ + ++LE ++ + + K +
Sbjct: 125 MEENEQLKAEVKDLQQEIEEMQDQYREEEI--EEFRELQRELELNAKNCRVLQFKLRKTE 182
Query: 508 KLYSQLRQEHLNILKKMKKTQDDLAEA--------ESEVKKLKSS--ALSNVGIRNNNKG 557
+ Q E ++ KK+ + + EA ++VK+L+ V +R +N+
Sbjct: 183 RSRDQAEAEKMHSEKKLDEYMNSCPEAVAASIKSDSAKVKELEYEIRVAKEVSVRLHNEL 242
Query: 558 ESEREE 563
E E+
Sbjct: 243 EQTEEK 248
>7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1690
Score = 46.2 bits (108), Expect = 2e-04
Identities = 54/242 (22%), Positives = 106/242 (43%), Gaps = 32/242 (13%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLA 507
+EKE+ I+Q+ A QN++ F+ + +V L++ + Q + + E V E +SL
Sbjct: 727 LEKES-IEQQLALKQNELEDFQKKQSESEVHLQEI--KAQNTQKDFELV----ESGESLK 779
Query: 508 KLYSQLRQEHLN------ILKKMKKTQDD-LAEAESEVKKLKS------SALSNVGIRNN 554
KL QL Q+ L L+++KK ++ + E E E+++L+S SAL V ++
Sbjct: 780 KLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLE 839
Query: 555 NKGESEREEAKDRSGMI---------LKSLVESSIKSLQDPIASLDVSDLATDLSNAFID 605
+ ++ S + LKS E + L+ ++L+ + +N ++
Sbjct: 840 QLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLE 899
Query: 606 GDINTIVNILPEFVSLLLRCPQEMQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKRLGE 665
+ ++L + L + ++ S KQ ++ AN A ++ K E
Sbjct: 900 EEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEA---ANAALEKVNKEYAE 956
Query: 666 IR 667
R
Sbjct: 957 SR 958
Score = 36.2 bits (82), Expect = 0.17
Identities = 43/219 (19%), Positives = 89/219 (40%), Gaps = 23/219 (10%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLA 507
M E LI++ T K + + + L++ K+ ++LE +L+ ++ ++K
Sbjct: 1161 MNSERLIEKVTG--------IKEELKETHLQLDERQKKFEELEEKLKQAQQSEQK----- 1207
Query: 508 KLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIR-NNNKGESEREEAKD 566
L+QE +K+ + Q L E + VK+ K + N+ + + E + K
Sbjct: 1208 -----LQQESQTSKEKLTEIQQSLQELQDSVKQ-KEELVQNLEEKVRESSSIIEAQNTKL 1261
Query: 567 RSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCP 626
+ S +K QD + + A + G++ + + L++
Sbjct: 1262 NESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKV- 1320
Query: 627 QEMQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKRLGE 665
+E+ + E+ L+ +S Q D+ N QE L + E
Sbjct: 1321 EELVKVLEEKLQAATS--QLDAQQATNKELQELLVKSQE 1357
Score = 32.0 bits (71), Expect = 3.2
Identities = 20/83 (24%), Positives = 42/83 (50%), Gaps = 9/83 (10%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKE----FKEKYQS 505
KEAL Q+ +N + + + + +LE K +++ +LE ++ +E+
Sbjct: 1384 KEALCQK-----ENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSK 1438
Query: 506 LAKLYSQLRQEHLNILKKMKKTQ 528
LA+ SQL+Q + + K +++ Q
Sbjct: 1439 LAEQLSQLKQANEELQKSLQQKQ 1461
Score = 30.4 bits (67), Expect = 9.3
Identities = 41/196 (20%), Positives = 83/196 (41%), Gaps = 22/196 (11%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
+KE +Q++T+ L + K E+ K +Q+ + LE EF + K
Sbjct: 1427 QKERTLQEETSKLAEQLSQLKQAN-------EELQKSLQQKQLLLEKGNEFDTQLAEYQK 1479
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKL----KSSALSNVGIRNNNKGESEREEA 564
+ ++ +++ Q+ +AE E+ +++ K++ L +R + E
Sbjct: 1480 VIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLE---SLELE 1536
Query: 565 KDRSGMILKSLVE--SSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLL 622
K R + LK+ + SS D + SLD+ T L+ +N+I+ + + L
Sbjct: 1537 KSREVLSLKAQMNGASSRSGKGDEVESLDIE---TSLAKI---NFLNSIIADMQQKNDAL 1590
Query: 623 LRCPQEMQTIAEDFLR 638
Q ++T+ DF +
Sbjct: 1591 KAKVQTLETLPMDFTK 1606
>Hs10864047 [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 864
Score = 45.1 bits (105), Expect = 4e-04
Identities = 40/149 (26%), Positives = 68/149 (44%), Gaps = 27/149 (18%)
Query: 449 EKEALIQQKTAS---LQNDI-------MSFKNQYERDQVMLEQYDKRVQKLESELESVKE 498
EKE I+QKT+ LQND+ + Q + Q L++ D++ KL L V++
Sbjct: 409 EKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQ 468
Query: 499 FKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGE 558
K Q ++ S L+ + + +K +DDL A+SE+ +L+ E
Sbjct: 469 ---KCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQ--------------E 511
Query: 559 SEREEAKDRSGMILKSLVESSIKSLQDPI 587
+ E ++G + + S+KS QD I
Sbjct: 512 ETQLEQSIQAGRVQLETIIKSLKSTQDEI 540
Score = 35.4 bits (80), Expect = 0.29
Identities = 24/102 (23%), Positives = 52/102 (50%), Gaps = 11/102 (10%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKE----FKEKYQSLAKL 509
+ Q+ A L++ + + + + + M+ ++Q ES+L+S ++ K + L +
Sbjct: 452 MDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQE 511
Query: 510 YSQLRQ-------EHLNILKKMKKTQDDLAEAESEVKKLKSS 544
+QL Q + I+K +K TQD++ +A S++ +L S
Sbjct: 512 ETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHES 553
>YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 1790
Score = 44.3 bits (103), Expect = 6e-04
Identities = 33/152 (21%), Positives = 77/152 (49%), Gaps = 12/152 (7%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESEL----ESVKEFKEKYQ 504
E +A +++ L+ + K + E+ + M+++ + ++ E+EL E++++ EK +
Sbjct: 1477 ESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLE 1536
Query: 505 SLAKLYSQ----LRQEHLNILKKMKKTQDDLAEAESE--VKKLKSSALSNVGIRNNNKGE 558
K + L+ E +++ ++ +++ D+ E +S+ ++ S L V NN E
Sbjct: 1537 QSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQE 1596
Query: 559 SEREEAKDRSGMILKSLVESSIKSLQDPIASL 590
R A++ + +LKS +E + L+D A +
Sbjct: 1597 KIRINAEENT--VLKSKLEDIERELKDKQAEI 1626
Score = 43.5 bits (101), Expect = 0.001
Identities = 57/248 (22%), Positives = 119/248 (47%), Gaps = 24/248 (9%)
Query: 455 QQKTASLQNDIMSFKNQYERDQ---VMLEQYDKR-VQKLESELESVKEFKEKY-QSLAKL 509
Q SLQ++I+S+K++ R+ + +E+ +KR ++ L+ +L + +E K K + L KL
Sbjct: 1430 QNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLKKL 1489
Query: 510 YSQLRQEHLNILKK---MKKTQDDLAEAESEVK-KLKSSALSNVGIRNNNKGESEREEAK 565
+ +E + K MKK + + E+E+K +++ S+ + + K E +
Sbjct: 1490 EEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNL 1549
Query: 566 DRSGMILKSLVESSIKSLQDPIASLDV-----SDLAT---DLSNA----FIDGDINTIVN 613
L S + S K +++ + L + S+L T +L+NA I+ + NT++
Sbjct: 1550 QHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENTVLK 1609
Query: 614 ILPEFVSLLLRCPQ-EMQTIAEDFLRCLSSAKQTDSVINA--NIAFQEKLKRLGEIRQYS 670
E + L+ Q E+++ E+ S K+ + +++ A + + +R E+R++
Sbjct: 1610 SKLEDIERELKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKSEEERRAEVRKFQ 1669
Query: 671 YRYGDSDE 678
DE
Sbjct: 1670 VEKSQLDE 1677
Score = 40.4 bits (93), Expect = 0.009
Identities = 40/145 (27%), Positives = 70/145 (47%), Gaps = 15/145 (10%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVK----EFKEKYQS----L 506
Q++T SL+ DI + + + LE+ + L E E + E+K ++QS +
Sbjct: 898 QKETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLV 957
Query: 507 AKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKD 566
AKL +L+ N K M+ + L +A E K S LSN+ NK +S +E +
Sbjct: 958 AKLTEKLK-SLANNYKDMQAENESLIKAVEESKNESSIQLSNL----QNKIDSMSQEKE- 1011
Query: 567 RSGMILKSLVESSIKSLQDPIASLD 591
+ I + +E +I+ L+ I+ L+
Sbjct: 1012 -NFQIERGSIEKNIEQLKKTISDLE 1035
Score = 35.8 bits (81), Expect = 0.22
Identities = 38/165 (23%), Positives = 73/165 (44%), Gaps = 24/165 (14%)
Query: 459 ASLQNDIMSFKNQYERDQVMLEQYDKRVQKLE---SELESVKE--------FKEKYQSLA 507
++LQN I S + E Q+ +K +++L+ S+LE KE K++Y+S
Sbjct: 997 SNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQI 1056
Query: 508 KLYSQ-------LRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNN--NKGE 558
L + E++N + ++ KT+++L + K LK+ + + + +
Sbjct: 1057 SLLKEKLETATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVK 1116
Query: 559 SEREEAKDRSGMILKSLVES--SIKSLQDPIASLDV--SDLATDL 599
E K+ + K E+ + SL+ + SL+ DLA L
Sbjct: 1117 ENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQL 1161
Score = 35.8 bits (81), Expect = 0.22
Identities = 31/150 (20%), Positives = 72/150 (47%), Gaps = 16/150 (10%)
Query: 461 LQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKE-----------FKEKYQSLAKL 509
L+ ++ ++KN + LE +K +++++ E +KE K++ SL
Sbjct: 1087 LEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRAN 1146
Query: 510 YSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSG 569
L +EH ++ ++KK ++ +A E + + + S L++ + ES +++ + G
Sbjct: 1147 LESLEKEHEDLAAQLKKYEEQIANKERQYNE-EISQLNDEITSTQQENESIKKKNDELEG 1205
Query: 570 MI--LKSLVE--SSIKSLQDPIASLDVSDL 595
+ +KS E S++K + +L + +L
Sbjct: 1206 EVKAMKSTSEEQSNLKKSEIDALNLQIKEL 1235
Score = 33.5 bits (75), Expect = 1.1
Identities = 53/217 (24%), Positives = 93/217 (42%), Gaps = 40/217 (18%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E+ +Q++ L+ +I S + + E ++ +KL + KE EKYQ L
Sbjct: 730 EEVEKLQRQCTKLKGEITSLQTETE------STHENLTEKLIALTNEHKELDEKYQILNS 783
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
+S L+ E+ +IL E+E+K ++ S +R + E KD+
Sbjct: 784 SHSSLK-ENFSIL-------------ETELKNVRDSLDEMTQLR-------DVLETKDKE 822
Query: 569 GMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCPQE 628
+S+I +D I +L+ L T LS D +N + + + L R E
Sbjct: 823 NQTALLEYKSTIHKQEDSIKTLE-KGLETILSQKKKAED---GINKMGKDLFALSR---E 875
Query: 629 MQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKRLGE 665
MQ + E+ C + K+ D +N+ Q++ K L E
Sbjct: 876 MQAVEEN---CKNLQKEKD---KSNVNHQKETKSLKE 906
>Hs15011904 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein) and related
proteins
Length = 5430
Score = 43.5 bits (101), Expect = 0.001
Identities = 51/226 (22%), Positives = 101/226 (44%), Gaps = 23/226 (10%)
Query: 449 EKEALIQQKTASL--QNDIMSFKN-----QYERDQVMLEQYDKRVQKLESELESVKEFKE 501
E++ ++Q+KT SL Q + +S N + ER QV++ Q+ + ++L +E +
Sbjct: 3787 EQKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIA 3846
Query: 502 KYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESER 561
+ S A + QLRQ+ ++M++ ++ +AE + + KL ++ N E E
Sbjct: 3847 QLPSPAIDHEQLRQQQ----EEMRQLRESIAEHKPHIDKLLKIGPQ---LKELNPEEGEM 3899
Query: 562 EEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAF--IDGDINTIVNILPEFV 619
E K + + + ++ ++ Q +A + +T ++ I+ + T+ N+
Sbjct: 3900 VEEKYQKAENMYAQIKEEVR--QRALALDEAVSQSTQITEFHDKIEPMLETLENL----- 3952
Query: 620 SLLLRCPQEMQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKRLGE 665
S LR P + + C+S K + E LKR GE
Sbjct: 3953 SSRLRMPPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGE 3998
Score = 30.4 bits (67), Expect = 9.3
Identities = 27/125 (21%), Positives = 54/125 (42%), Gaps = 17/125 (13%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQS-LA 507
E++ ++QQK L K QY E K+VQ L+ EL+ + ++++S L
Sbjct: 1780 EEQQMLQQKLGEL-------KEQYSTSLAQSEAELKQVQTLQDELQKFLQDHKEFESWLE 1832
Query: 508 KLYSQLRQEHL---------NILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGE 558
+ +L H ++LK+ +D+ + +++ + S + + N+ K
Sbjct: 1833 RSEKELENMHKGGSSPETLPSLLKRQGSFSEDVISHKGDLRFVTISGQKVLDMENSFKEG 1892
Query: 559 SEREE 563
E E
Sbjct: 1893 KEPSE 1897
>7298332 [BD] KOG0996 Structural maintenance of chromosome protein 4
(chromosome condensation complex Condensin subunit C)
Length = 1409
Score = 43.1 bits (100), Expect = 0.001
Identities = 60/254 (23%), Positives = 107/254 (41%), Gaps = 34/254 (13%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKR-------VQKLESELESVKEFKE 501
E EAL++ K ++ +++ ++ Y Q +E +K+ ++K E ELE + + E
Sbjct: 380 EYEALVK-KREQIKKRLVTVESAYTEIQSTMENTNKQRKKDKAQIEKNEKELEDLHKLPE 438
Query: 502 KYQ----SLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEV--KKLKSSALSNVGIR--- 552
K Q K L + + ++++K Q +L + + + K+LK S VG++
Sbjct: 439 KNQREIEDCNKKLESLEVSKVTLNEELEKQQAELTKTTAPLTEKRLKLSD-ELVGLKEKV 497
Query: 553 NNNKGE-----------SEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSN 601
N KGE + E + R LKS E S KSL++ + +D +
Sbjct: 498 NTAKGEVQVFESQLKILKQAETTESRKYETLKSSYEQSQKSLEEKVTRVDELKESIPRMK 557
Query: 602 AFIDGDINTIVNILPEFVSLLLRCPQEMQTIAEDFLRCLSSAKQTDSVINANIAFQEKLK 661
I + ++ E +L ++C + I E SS Q N + F ++K
Sbjct: 558 TEIASKSAEVDKMVKEERNLSMQCNKLRTEINE-----RSSVMQAQRSNNKVLDFLMRMK 612
Query: 662 RLGEIRQYSYRYGD 675
G+I R GD
Sbjct: 613 MEGKIPGILGRLGD 626
Score = 38.5 bits (88), Expect = 0.034
Identities = 39/159 (24%), Positives = 74/159 (46%), Gaps = 10/159 (6%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELES-VKEFKEKYQSLAKLYSQL 513
Q++ SL+ +I + KN +RD+ ++ + LE ++ S +K+ + + Q + K +
Sbjct: 808 QEQQGSLEREIQTLKNGLQRDEAEYKRLAVSITSLEQQMASNLKQCEAQRQRMLKKTTDE 867
Query: 514 RQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEA-KDRSGMIL 572
R K ++ Q + A+ E E + A+S+ N+ ++ R E+ K I
Sbjct: 868 R------AVKEREEQIEAAKQELEQAQFAEQAVSSQIEEIQNQYDTLRNESVKPVEAKIK 921
Query: 573 KSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTI 611
K V S I+ L + SL+V D + I G+ N +
Sbjct: 922 K--VNSQIEKLAANVRSLNVGLATADRNITKITGNNNNL 958
>YHR023w [Z] KOG0161 Myosin class II heavy chain
Length = 1928
Score = 42.7 bits (99), Expect = 0.002
Identities = 33/133 (24%), Positives = 69/133 (51%), Gaps = 15/133 (11%)
Query: 456 QKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQ 515
Q + +D+ S +++++ L + +++ ESEL +KE + ++ +S+ R
Sbjct: 1064 QSLVTENSDLRSKNENFKKEKAAL---NNQLKNKESELLKMKEKIDNHKKELATFSKQRD 1120
Query: 516 ----EHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMI 571
EH I ++K+T+ L E +S +K+K +N + E++ +E K R+ ++
Sbjct: 1121 DAVSEHGKITAELKETRIQLTEYKSNYQKIKEE-------YSNFQRETKEQEQKKRNSLV 1173
Query: 572 LKSLVESSIKSLQ 584
+SL +S IK L+
Sbjct: 1174 -ESLNDSKIKELE 1185
Score = 39.3 bits (90), Expect = 0.020
Identities = 34/144 (23%), Positives = 63/144 (43%), Gaps = 20/144 (13%)
Query: 451 EALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEK-------- 502
++LI++ L+N+I K+ + ++ ++ ++ E +L+ EK
Sbjct: 1003 QSLIKESKLKLENEIKRLKDVINSKEEEIKSFNDKLSSSEEDLDIKLVTLEKNCNIAMSR 1062
Query: 503 YQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGE---- 558
QSL S LR ++ N K+ + L ESE+ K+K +N+K E
Sbjct: 1063 LQSLVTENSDLRSKNENFKKEKAALNNQLKNKESELLKMKEKI-------DNHKKELATF 1115
Query: 559 -SEREEAKDRSGMILKSLVESSIK 581
+R++A G I L E+ I+
Sbjct: 1116 SKQRDDAVSEHGKITAELKETRIQ 1139
Score = 33.5 bits (75), Expect = 1.1
Identities = 43/184 (23%), Positives = 82/184 (44%), Gaps = 28/184 (15%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKL 509
KEAL+ ++ LQ D+ S + Q E ++Q ++ + +L+
Sbjct: 1449 KEALLSEQLDRLQKDLESTERQKELLSSTIKQQKQQFENCMDDLQG-------------- 1494
Query: 510 YSQLR-QEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
++LR +EH++ L K+ ++D+ S ++KLK+ + K ERE ++ S
Sbjct: 1495 -NELRLREHIHAL---KQAEEDVKNMASIIEKLKTQN------KQKEKLIWEREMERNDS 1544
Query: 569 GMILKSLVESSIKSLQD--PIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCP 626
M L+ + +K +QD I S D++ L LS +N L E ++ L+
Sbjct: 1545 DMQLQETL-LELKRVQDVKKILSDDLAHLKERLSAVEDRSQYTDEINRLKEELNCSLKAE 1603
Query: 627 QEMQ 630
++
Sbjct: 1604 TNLK 1607
>Hs14149661 [U] KOG4809 Rab6 GTPase-interacting protein involved in
endosome-to-TGN transport
Length = 948
Score = 42.7 bits (99), Expect = 0.002
Identities = 48/217 (22%), Positives = 102/217 (46%), Gaps = 28/217 (12%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQV-----MLEQYDKRVQKLESELESVKEF---K 500
EKE ++ +KT +Q+ M+ + + ++ ML+ +++V L+ ++E+++E K
Sbjct: 505 EKETMLNKKTKQIQD--MAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 562
Query: 501 EKYQS-LAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGES 559
EK S L + L+ + N + ++ LAE E +++LK ++ E
Sbjct: 563 EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLK---------EQRDRDER 613
Query: 560 EREEAKDRSGMILKSLVESSIKSLQDPIAS-----LDVSDLATDLSNAFI--DGDINTIV 612
E++E D LK L E + LQ ++ LD+ + A+ L+++ + D + T+
Sbjct: 614 EKQEEIDNYKKDLKDLKE-KVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLE 672
Query: 613 NILPEFVSLLLRCPQEMQTIAEDFLRCLSSAKQTDSV 649
L + L+ +++ E L +S + +D +
Sbjct: 673 IALEQKKEECLKMESQLKKAHEAALEARASPEMSDRI 709
Score = 33.5 bits (75), Expect = 1.1
Identities = 27/142 (19%), Positives = 63/142 (44%), Gaps = 1/142 (0%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E E+L ++ + + K++ + ++ Q + ++ E L + + + + L
Sbjct: 753 ELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQ-QLQVEELLM 811
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
+++QE ++ K+ TQ LAE E+ + L++ ++ K E+ ++
Sbjct: 812 AMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKD 871
Query: 569 GMILKSLVESSIKSLQDPIASL 590
I + SS K Q+ +A+L
Sbjct: 872 ANIALLELSSSKKKTQEEVAAL 893
Score = 33.1 bits (74), Expect = 1.4
Identities = 31/145 (21%), Positives = 75/145 (51%), Gaps = 17/145 (11%)
Query: 449 EKEALI---QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQS 505
EKEA + ++ +SL + + ++ + ++ LEQ + K+ES+L+ E + ++
Sbjct: 642 EKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARA 701
Query: 506 LAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAK 565
++ ++ +HL +++ + +D+ ++A++EV +L + + E+E+ + K
Sbjct: 702 SPEMSDRI--QHLE--REITRYKDESSKAQAEVDRL---------LEILKEVENEKND-K 747
Query: 566 DRSGMILKSLVESSIKSLQDPIASL 590
D+ L+SL +K +A+L
Sbjct: 748 DKKIAELESLTSRQVKDQNKKVANL 772
>At2g01600 [TU] KOG0251 Clathrin assembly protein AP180 and related proteins
contain ENTH domain
Length = 571
Score = 42.7 bits (99), Expect = 0.002
Identities = 61/294 (20%), Positives = 123/294 (41%), Gaps = 32/294 (10%)
Query: 9 MSREEQTLEKSIKKALSGGDVAPKRKHVRACIVYTWDHKSSKTF---FNLLKLQPYATDE 65
++ E L+ +I KA + + PK +H+R T ++ + L + + T
Sbjct: 25 VNSEYADLDVAIVKATNHVECPPKDRHLRKIFAATSVTRARADVAYCIHALSRRLHKTRN 84
Query: 66 LQL-FKALVLLHKVLQEGHPSALVEGIRNIDWIESLSRIFSVDS--DDGSKYGSSRMRYI 122
+ K L+++H++L+EG P+ E + RI + + DD S I
Sbjct: 85 WTVALKTLIVIHRLLREGDPTFREELLN----FSQRGRILQLSNFKDDSSP--------I 132
Query: 123 GDEYAKAIGEYVFFLVEKLQFHKSHKGFNGIFEYEEYVSLVSVSDP--NEGYETVLDL-- 178
+ + + Y FL E+L+ + + +Y+ + S+P ++GY DL
Sbjct: 133 AWDCSAWVRTYALFLEERLECFR-------VLKYDTEAERLPKSNPGQDKGYSRTRDLDG 185
Query: 179 MNLEDVADNLQKLIFAGISNRKSGFGSFSSGLDCRGAVLIPLVSETYGIFKFVTSMMKAL 238
L + LQ+L++ I R G + + + A+++ + Y +
Sbjct: 186 EELLEQLPALQQLLYRLIGCRPEGAANHNHVIQYALALVLKESFKVYCAINDGIINLIDK 245
Query: 239 YKQMGDYDALSGL--FDRYTEQCARLNEFYFDCNTVQPLKNLITIPTLPSDPMS 290
+ +M ++A++ L + R +Q L++FY C ++ +N P L P S
Sbjct: 246 FFEMAKHEAITSLEIYKRAGQQARSLSDFYEACKGLELARN-FQFPVLREPPQS 298
>Hs7669506 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 42.0 bits (97), Expect = 0.003
Identities = 43/221 (19%), Positives = 93/221 (41%), Gaps = 23/221 (10%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESEL----ESVKEFKEKYQSLAKLY 510
Q+++ SL ++ KN YE LE + + L+ E+ E + E ++ L K+
Sbjct: 1475 QKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIK 1534
Query: 511 SQLRQEHLNILKKMKKTQDDLAEAESEVKKLK---SSALSNVGIRNNNKGESEREEAKDR 567
Q+ QE + +++ + L E ++ +++ + S V + K E + ++
Sbjct: 1535 KQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNH 1594
Query: 568 SGMI--LKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTI---VNILPEFVSLL 622
++ ++S +++ I+S D I ++GD+N + +N +
Sbjct: 1595 IRIVESMQSTLDAEIRSRNDAIR-----------LKKKMEGDLNEMEIQLNHANRMAAEA 1643
Query: 623 LRCPQEMQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKRL 663
LR + Q I +D L A ++ + +A E+ L
Sbjct: 1644 LRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANL 1684
Score = 37.7 bits (86), Expect = 0.058
Identities = 34/155 (21%), Positives = 75/155 (47%), Gaps = 25/155 (16%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQY-ERDQVMLEQYDKRVQKLESEL-------------- 493
+ A +++ +L+ + +++ E +Q+ L+ K++QKLE+ +
Sbjct: 1778 DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRN 1837
Query: 494 -ESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSA-----LS 547
E+VK ++ + + +L Q ++ NIL+ QD + + +++VK K A S
Sbjct: 1838 VEAVKGLRKHERKVKELTYQTEEDRKNILR----LQDLVDKLQAKVKSYKRQAEEAEEQS 1893
Query: 548 NVGIRNNNKGESEREEAKDRSGMILKSLVESSIKS 582
NV + + + E EEA++R+ + + + +KS
Sbjct: 1894 NVNLSKFRRIQHELEEAEERADIAESQVNKLRVKS 1928
Score = 33.1 bits (74), Expect = 1.4
Identities = 38/203 (18%), Positives = 88/203 (42%), Gaps = 30/203 (14%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
+Q+K LQ I + + E ++ + +K+ L ELE + E E+ ++
Sbjct: 1108 LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEM 1167
Query: 514 RQEHLNILKKMKKTQDDLAEA-------ESEVKKLKSSALSNVGIRNNNKGESEREEAKD 566
++ +KM++ DL EA + ++K + +++ +G + +N +++ K+
Sbjct: 1168 NKKREAEFQKMRR---DLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKE 1224
Query: 567 RSGMILKSLVESSIKSLQDPIASLDVSDLATDLSN-AFIDGDINTIVNILPEFVSLLLRC 625
+S M +++ DLA+++ + G++ + L + +S +
Sbjct: 1225 KSEM------------------KMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTK 1266
Query: 626 PQEMQTIAEDFLRCLSSAKQTDS 648
+E Q + D L + QT+S
Sbjct: 1267 EEEQQRLIND-LTAQRARLQTES 1288
Score = 31.2 bits (69), Expect = 5.4
Identities = 28/143 (19%), Positives = 61/143 (42%), Gaps = 3/143 (2%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E A + K L+++ K + ++ L + +K E++ VK E+ L +
Sbjct: 935 EINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK---VKNLTEEMAGLDE 991
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
++L +E + + ++T DDL E +V L + + ++ +G E+E+
Sbjct: 992 TIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMD 1051
Query: 569 GMILKSLVESSIKSLQDPIASLD 591
K +E +K Q+ ++
Sbjct: 1052 LERAKRKLEGDLKLAQESAMDIE 1074
>Hs20542063 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 42.0 bits (97), Expect = 0.003
Identities = 53/223 (23%), Positives = 91/223 (40%), Gaps = 27/223 (12%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESEL----ESVKEFKEKYQSLAKLY 510
Q++ SL ++ KN YE LE + + + L+ E+ E + E + L K+
Sbjct: 1473 QKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVR 1532
Query: 511 SQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGM 570
QL E L + Q L EAE+ ++ + L N K E ER+ A+ M
Sbjct: 1533 KQLEVEKLEL-------QSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEM 1585
Query: 571 ILKSLVESSIKSLQDPIASLDVS-DLATDLSNAFI------DGDINTIVNILPEFVSLLL 623
E + ++ Q + SL S D T N + +GD+N + L +
Sbjct: 1586 ------EQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAA 1639
Query: 624 RCPQE---MQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKRL 663
++ +Q++ +D L A + + + NIA E+ L
Sbjct: 1640 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL 1682
Score = 36.2 bits (82), Expect = 0.17
Identities = 34/161 (21%), Positives = 68/161 (42%), Gaps = 3/161 (1%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E A + K L+++ K + ++ L + +K E++ VK E+ L +
Sbjct: 933 EMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK---VKNLTEEMAGLDE 989
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
+ ++L +E + + ++ DDL E +V L S + ++ +G E+E+
Sbjct: 990 IIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMD 1049
Query: 569 GMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDIN 609
K +E +K Q+ I L+ L + + DIN
Sbjct: 1050 LERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDIN 1090
Score = 33.5 bits (75), Expect = 1.1
Identities = 35/207 (16%), Positives = 86/207 (40%), Gaps = 19/207 (9%)
Query: 457 KTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQE 516
K+A + ++ + K ++ R + LE+ + R ++LE ++ S L QE
Sbjct: 843 KSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVS-----------------LLQE 885
Query: 517 HLNILKKMKKTQDDLAEAESEVKKL-KSSALSNVGIRNNNKGESEREEAKDRSGMILKSL 575
++ +++ QD+L +AE +L K+ ++ N+ E EE + K
Sbjct: 886 KNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNE-RLEDEEEMNAELTAKKRK 944
Query: 576 VESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCPQEMQTIAED 635
+E L+ I L+++ + + + + + ++ + +E + + E
Sbjct: 945 LEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA 1004
Query: 636 FLRCLSSAKQTDSVINANIAFQEKLKR 662
+ L + + +N+ + KL++
Sbjct: 1005 HQQALDDLQVEEDKVNSLSKSKVKLEQ 1031
>CE27773 [Z] KOG0517 Beta-spectrin
Length = 4063
Score = 42.0 bits (97), Expect = 0.003
Identities = 29/120 (24%), Positives = 63/120 (52%), Gaps = 2/120 (1%)
Query: 453 LIQQKTASLQNDIMSFKNQY-ERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYS 511
L+ +K ++L+ D+ + + D+ + +KR E+ L+S+K+ +E ++ L+K +
Sbjct: 2447 LLVRKQSALERDMSAIHQKLIAHDKDAQKILEKRPPLRETVLDSLKKLEESWEQLSKA-A 2505
Query: 512 QLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMI 571
+LR E LN K+ K DD+ + E ++++ S+ +++N E+ +R I
Sbjct: 2506 ELRNEKLNRSFKLYKYLDDVKKVEQWANQVRNKMTSHQTPKDSNGARKILEQHHERKAEI 2565
>Hs4503593 [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 896
Score = 41.2 bits (95), Expect = 0.005
Identities = 27/104 (25%), Positives = 58/104 (54%), Gaps = 13/104 (12%)
Query: 449 EKEALIQQKTASLQN----------DIMSFKNQYERDQVMLEQYDKRVQKLESELESVKE 498
EKE I+Q+T+ +Q+ ++ + Q ++ Q +L++ D++ +LE E +KE
Sbjct: 358 EKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLE---EQLKE 414
Query: 499 FKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLK 542
++K A+L S L+ E + ++ +++LA+A E+ +L+
Sbjct: 415 VRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQ 458
>Hs13124879 [Z] KOG0161 Myosin class II heavy chain
Length = 1972
Score = 41.2 bits (95), Expect = 0.005
Identities = 42/199 (21%), Positives = 82/199 (41%), Gaps = 16/199 (8%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESV-------KEFKEKYQSL 506
+++ Q +I + QYE ++ +K +L+ EL+ + ++ +
Sbjct: 1390 LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1449
Query: 507 AKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKD 566
+ + QL E NI K + D AEAE+ K+ K+ +L+ + E +E +
Sbjct: 1450 QRKFDQLLAEEKNISSKY-ADERDRAEAEAREKETKALSLARA-----LEEALEAKEELE 1503
Query: 567 RSGMILKSLVESSIKSLQD---PIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLL 623
R+ +LK+ +E + S D + L+ S A + + + + + L L
Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1563
Query: 624 RCPQEMQTIAEDFLRCLSS 642
R MQ + F R L +
Sbjct: 1564 RLEVNMQALKGQFERDLQA 1582
Score = 35.8 bits (81), Expect = 0.22
Identities = 33/156 (21%), Positives = 69/156 (44%), Gaps = 34/156 (21%)
Query: 479 LEQYDKRVQKLESELESVKE-----------FKEKYQSLAKLYSQLRQEHLNILKKMKKT 527
L++ +R QK E+EL+ +++ +E+ Q+ +LY++ + + + K ++
Sbjct: 861 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL 920
Query: 528 QDDLAEAESEVKKLKSSALSNVGIRNNN-------KGESEREEAKDRSGMILKSLVESSI 580
++ L E E+ +++ + R + + E EEA + + K E+ I
Sbjct: 921 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI 980
Query: 581 KSLQDPIASLD----------------VSDLATDLS 600
K L+D I +D +SDL T+L+
Sbjct: 981 KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016
Score = 32.0 bits (71), Expect = 3.2
Identities = 34/164 (20%), Positives = 71/164 (42%), Gaps = 22/164 (13%)
Query: 452 ALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYS 511
A ++ K A L+ + + + L+Q DK+++++ ++E ++ E+Y+ A+ +
Sbjct: 1817 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
Query: 512 QLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMI 571
++K+ + L EAE E +++ ++ ++ +E EA R
Sbjct: 1877 ----------ARVKQLKRQLEEAEEESQRINANRRK---LQRELDEATESNEAMGREVNA 1923
Query: 572 LK---------SLVESSIKSLQDPIASLDVSDLATDLSNAFIDG 606
LK S V S + I + D S+ TD +A +G
Sbjct: 1924 LKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETDTRDADFNG 1967
>Hs13124875 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 41.2 bits (95), Expect = 0.005
Identities = 42/199 (21%), Positives = 82/199 (41%), Gaps = 16/199 (8%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESV-------KEFKEKYQSL 506
+++ Q +I + QYE ++ +K +L+ EL+ + ++ +
Sbjct: 1390 LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1449
Query: 507 AKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKD 566
+ + QL E NI K + D AEAE+ K+ K+ +L+ + E +E +
Sbjct: 1450 QRKFDQLLAEEKNISSKY-ADERDRAEAEAREKETKALSLARA-----LEEALEAKEELE 1503
Query: 567 RSGMILKSLVESSIKSLQD---PIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLL 623
R+ +LK+ +E + S D + L+ S A + + + + + L L
Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1563
Query: 624 RCPQEMQTIAEDFLRCLSS 642
R MQ + F R L +
Sbjct: 1564 RLEVNMQALKGQFERDLQA 1582
Score = 35.8 bits (81), Expect = 0.22
Identities = 33/156 (21%), Positives = 69/156 (44%), Gaps = 34/156 (21%)
Query: 479 LEQYDKRVQKLESELESVKE-----------FKEKYQSLAKLYSQLRQEHLNILKKMKKT 527
L++ +R QK E+EL+ +++ +E+ Q+ +LY++ + + + K ++
Sbjct: 861 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL 920
Query: 528 QDDLAEAESEVKKLKSSALSNVGIRNNN-------KGESEREEAKDRSGMILKSLVESSI 580
++ L E E+ +++ + R + + E EEA + + K E+ I
Sbjct: 921 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI 980
Query: 581 KSLQDPIASLD----------------VSDLATDLS 600
K L+D I +D +SDL T+L+
Sbjct: 981 KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016
Score = 31.2 bits (69), Expect = 5.4
Identities = 25/123 (20%), Positives = 57/123 (46%), Gaps = 13/123 (10%)
Query: 452 ALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYS 511
A ++ K A L+ + + + L+Q DK+++++ ++E ++ E+Y+ A+ +
Sbjct: 1817 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
Query: 512 QLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMI 571
++K+ + L EAE E +++ ++ ++ +E EA R
Sbjct: 1877 ----------ARVKQLKRQLEEAEEESQRINANRRK---LQRELDEATESNEAMGREVNA 1923
Query: 572 LKS 574
LKS
Sbjct: 1924 LKS 1926
>YIL138c [Z] KOG1003 Actin filament-coating protein tropomyosin
Length = 161
Score = 40.8 bits (94), Expect = 0.007
Identities = 35/147 (23%), Positives = 67/147 (44%), Gaps = 11/147 (7%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
EK ++++ L+ +N+ + EQ D V+KLES+L K+ LA+
Sbjct: 20 EKYEELREQLKELEQSNTEKENEIKSLSAKNEQLDSEVEKLESQLSDTKQ-------LAE 72
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVK----KLKSSALSNVGIRNNNKGESEREEA 564
+ LR + N KK + + L ++E+++K KLK + L++ + E +
Sbjct: 73 DSNNLRSNNENYTKKNQDLEQQLEDSEAKLKEAMDKLKEADLNSEQMGRRIVALEEERDE 132
Query: 565 KDRSGMILKSLVESSIKSLQDPIASLD 591
++ +S E + K L + SL+
Sbjct: 133 WEKKCEEFQSKYEEAQKELDEIANSLE 159
Score = 37.7 bits (86), Expect = 0.058
Identities = 25/117 (21%), Positives = 55/117 (46%), Gaps = 4/117 (3%)
Query: 486 VQKLESELESVK----EFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKL 541
++K++ +L S+K ++EKY+ L + +L Q + ++K + +SEV+KL
Sbjct: 1 MEKIKEKLNSLKLESESWQEKYEELREQLKELEQSNTEKENEIKSLSAKNEQLDSEVEKL 60
Query: 542 KSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATD 598
+S + ++ E + L+ +E S L++ + L +DL ++
Sbjct: 61 ESQLSDTKQLAEDSNNLRSNNENYTKKNQDLEQQLEDSEAKLKEAMDKLKEADLNSE 117
>SPCC645.05c [Z] KOG0161 Myosin class II heavy chain
Length = 1526
Score = 40.8 bits (94), Expect = 0.007
Identities = 21/69 (30%), Positives = 38/69 (54%)
Query: 479 LEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEV 538
LE Y K+ + L+ +LE +K+ +Q L+K + L H ++L++ ++ L+ A SE
Sbjct: 1167 LENYKKKYEGLQLDLEGLKDVDTNFQELSKKHRDLTFNHESLLRQSASYKEKLSLASSEN 1226
Query: 539 KKLKSSALS 547
K L + S
Sbjct: 1227 KDLSNKVSS 1235
Score = 30.4 bits (67), Expect = 9.3
Identities = 25/110 (22%), Positives = 55/110 (49%), Gaps = 7/110 (6%)
Query: 449 EKEALI----QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQ 504
+++ALI ++ SL++++ S + Q +LE+ K + L SE+ ++ ++
Sbjct: 1275 KRKALIASRDNEELRSLKSELESKRKLEVEYQKVLEEV-KTTRSLRSEVTLLRNKVADHE 1333
Query: 505 SLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNN 554
S+ S++ + ++ K++ D + E+E+ +LK S G NN
Sbjct: 1334 SIRSKLSEVEMKLVDTRKELNSALDSCKKREAEIHRLKEHRPS--GKENN 1381
>7292323 [S] KOG4643 Uncharacterized coiled-coil protein
Length = 1381
Score = 40.8 bits (94), Expect = 0.007
Identities = 29/142 (20%), Positives = 62/142 (43%), Gaps = 5/142 (3%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E+++ ++Q+ L + K E ++ ++ K + + FK +Y+++ +
Sbjct: 944 EQQSALEQRIEELTIQNSNMKTCSEDLSILRTEHSKLTDDFRNLFATSDRFKNEYKNIQE 1003
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKL-----KSSALSNVGIRNNNKGESEREE 563
Y +R EH ++ + + +L +V+ L K + I+NN + +SER+
Sbjct: 1004 QYKMVRMEHSSLKLQNTELSGELNAKSDQVRCLQMEYSKVQQRCEMLIQNNAELDSERKA 1063
Query: 564 AKDRSGMILKSLVESSIKSLQD 585
D +L E SL+D
Sbjct: 1064 LMDNVSQLLSQYQELLAISLED 1085
Score = 36.2 bits (82), Expect = 0.17
Identities = 26/120 (21%), Positives = 53/120 (43%), Gaps = 8/120 (6%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQ-------YDKRVQKLESELESVKEFKEKYQSLA 507
+++ ASL ++ K E+ V L+ K +QKL LE ++ +K L
Sbjct: 629 ERENASLLKEVSKLKEGSEQKSVQLDDSINRLDVQSKELQKLGKALEDSEQVHQKLVELE 688
Query: 508 KLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDR 567
K +L + + + + ++DL KK++++ L +G+ + GE E ++
Sbjct: 689 KQNQELASQRIIDQEMISTLRNDLVTGTLVTKKVRNN-LEKLGLADEEPGELNVEHVVEK 747
Score = 35.8 bits (81), Expect = 0.22
Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLA 507
+E+EA +QK + + + + + +R Q + E +R LE ES + E+Y +
Sbjct: 550 LEREA-DRQKLSDAEQHVETLNKEKQRIQTLNESIQRRADDLERLAESKTKELEQYLEKS 608
Query: 508 KLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSA 545
+ Y +Q+ I ++ + + A EV KLK +
Sbjct: 609 RQYELTKQKLYEIEARVSTYERENASLLKEVSKLKEGS 646
>Hs8923940 [Z] KOG0161 Myosin class II heavy chain
Length = 1941
Score = 40.4 bits (93), Expect = 0.009
Identities = 48/218 (22%), Positives = 92/218 (42%), Gaps = 17/218 (7%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESEL----ESVKEFKEKYQSLAKLY 510
Q++ SL ++ KN YE LE + + L+ E+ E + E ++ L K+
Sbjct: 1477 QKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIK 1536
Query: 511 SQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEA-KDRSG 569
Q+ QE + +++ + L E ++ +++ N K E +R+ A KD
Sbjct: 1537 KQVEQEKCELQAALEEAEASLEHEEGKILRIQLEL-------NQVKSEVDRKIAEKDEEI 1589
Query: 570 MILKSLVESSIKSLQDPI-ASLDVSDLATDLSNAFIDGDINTI---VNILPEFVSLLLRC 625
LK ++S+Q + A + + A L ++GD+N + +N + LR
Sbjct: 1590 DQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKK-MEGDLNEMEIQLNHANRMAAEALRN 1648
Query: 626 PQEMQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKRL 663
+ Q I +D L A ++ + +A E+ L
Sbjct: 1649 YRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANL 1686
Score = 33.5 bits (75), Expect = 1.1
Identities = 29/143 (20%), Positives = 62/143 (43%), Gaps = 3/143 (2%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E A + K L+++ K + ++ L + +K E++ VK E+ L +
Sbjct: 937 EINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK---VKNLTEEMAGLDE 993
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
++L +E + + ++T DDL E +V L + + ++ +G E+E+
Sbjct: 994 TIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMD 1053
Query: 569 GMILKSLVESSIKSLQDPIASLD 591
K +E +K Q+ I ++
Sbjct: 1054 LERAKRKLEGDLKLAQESIMDIE 1076
Score = 33.1 bits (74), Expect = 1.4
Identities = 39/203 (19%), Positives = 87/203 (42%), Gaps = 30/203 (14%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
+Q+K LQ I + + E ++ + +K+ L ELE + E E+ ++
Sbjct: 1110 LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEM 1169
Query: 514 RQEHLNILKKMKKTQDDLAEA-------ESEVKKLKSSALSNVGIRNNNKGESEREEAKD 566
++ +KM++ DL EA + ++K + +++ +G + +N +++ K+
Sbjct: 1170 NKKREAEFQKMRR---DLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKE 1226
Query: 567 RSGMILKSLVESSIKSLQDPIASLDVSDLATDLSN-AFIDGDINTIVNILPEFVSLLLRC 625
+S M +++ DLA+++ + G++ + L + +S L
Sbjct: 1227 KSEM------------------KMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSK 1268
Query: 626 PQEMQTIAEDFLRCLSSAKQTDS 648
+E Q + D L QT+S
Sbjct: 1269 EEEQQRLIND-LTAQRGRLQTES 1290
>CE15746 [DY] KOG0977 Nuclear envelope protein lamin intermediate filament
superfamily
Length = 566
Score = 40.4 bits (93), Expect = 0.009
Identities = 32/139 (23%), Positives = 71/139 (51%), Gaps = 17/139 (12%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKL 509
++A +++ S Q+++ ++ +Y+ +V +++ +V+KLE EL +E QS+A
Sbjct: 98 EKARLRRALDSAQDELAKYRIEYDAAKVEVKKLKPQVEKLERELAGAEEQALHAQSIAD- 156
Query: 510 YSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSG 569
SQ +Q K ++ D L ++KK N+ +R+ +G + E +
Sbjct: 157 QSQAKQ------KTLQARNDKLVVENDDLKK------QNITLRDTVEGLKKAVEDE---- 200
Query: 570 MILKSLVESSIKSLQDPIA 588
+L++ + IK+L++ +A
Sbjct: 201 TLLRTAANNKIKALEEDLA 219
>7293601 [T] KOG0577 Serine/threonine protein kinase
Length = 1039
Score = 40.4 bits (93), Expect = 0.009
Identities = 41/162 (25%), Positives = 67/162 (41%), Gaps = 23/162 (14%)
Query: 449 EKEALIQQKTASLQNDI--MSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQ-- 504
++E + + T Q D+ S K+ ++ + EQ + QK ELE +++FK K
Sbjct: 678 KRELSMDESTPKRQRDLTLQSQKDNLKQHEAQEEQRMLQAQKQYIELE-MRKFKRKRMIM 736
Query: 505 -----------SLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRN 553
L K QL+Q H +LK +KTQ+ + V +L+ +
Sbjct: 737 QHEHEDQQLRDELGKKEQQLQQAHAMLLKHHEKTQELEYRQQKSVHQLREEQI------- 789
Query: 554 NNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDL 595
N + ++E KD I K LV L+ SL +L
Sbjct: 790 NKQHDTELHNQKDYMDRIKKELVRKHAVELRQQPKSLKQKEL 831
>YLR337c [Z] KOG4462 WASP-interacting protein VRP1/WIP contains WH2 domain
Length = 817
Score = 40.0 bits (92), Expect = 0.012
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Query: 330 PSPVHEAPPVARPAEVRSLSQPAAPVVPIATGVVMPVVTGYSQPPLQVVPTGA--EFWSI 387
PSP APP+ P V S++ P P P++ +P + S PP+ +P+ A +
Sbjct: 114 PSPSASAPPI--PGAVPSVAAPPIPNAPLSPAPAVPSIPSSSAPPIPDIPSSAAPPIPIV 171
Query: 388 PSTSAP 393
PS+ AP
Sbjct: 172 PSSPAP 177
>7303911 [D] KOG4593 Mitotic checkpoint protein MAD1
Length = 730
Score = 40.0 bits (92), Expect = 0.012
Identities = 23/93 (24%), Positives = 48/93 (50%), Gaps = 4/93 (4%)
Query: 448 MEKEALIQQKTASLQNDI-MSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSL 506
++KE +Q++ A D+ + N+ + + ++ D +Q +ELE +++ E+ Q+
Sbjct: 171 LQKEKYLQKEDA---RDVHLCINNELSEYRRIAQRADLELQSTRNELERLRQLNEELQAR 227
Query: 507 AKLYSQLRQEHLNILKKMKKTQDDLAEAESEVK 539
A + QLR H + +K D + E E E++
Sbjct: 228 ASGFEQLRANHEKQTQSLKVANDRIQELEFEIQ 260
>Hs4557773 [Z] KOG0161 Myosin class II heavy chain
Length = 1935
Score = 39.7 bits (91), Expect = 0.015
Identities = 47/213 (22%), Positives = 86/213 (40%), Gaps = 7/213 (3%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLR 514
Q++ SL ++ KN YE LE + + + L+ E + + E+ S K +L
Sbjct: 1471 QKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQ---EEISDLTEQLGSSGKTIHELE 1527
Query: 515 QEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEA-KDRSGMILK 573
+ + + + Q L EAE+ ++ + L N K E ER+ A KD K
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1587
Query: 574 SLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCPQE---MQ 630
+ SLQ + + S ++GD+N + L + ++ +Q
Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1647
Query: 631 TIAEDFLRCLSSAKQTDSVINANIAFQEKLKRL 663
++ +D L A + + + NIA E+ L
Sbjct: 1648 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNL 1680
Score = 36.6 bits (83), Expect = 0.13
Identities = 37/207 (17%), Positives = 86/207 (40%), Gaps = 19/207 (9%)
Query: 457 KTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQE 516
K+A + ++ S K ++ R + LE+ + R ++LE ++ S L QE
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVS-----------------LLQE 883
Query: 517 HLNILKKMKKTQDDLAEAESEVKKL-KSSALSNVGIRNNNKGESEREEAKDRSGMILKSL 575
++ +++ QD+LA+AE +L K+ ++ N+ E EE + K
Sbjct: 884 KNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNE-RLEDEEEMNAELTAKKRK 942
Query: 576 VESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCPQEMQTIAED 635
+E L+ I L+++ + + + + + ++ + +E + + E
Sbjct: 943 LEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA 1002
Query: 636 FLRCLSSAKQTDSVINANIAFQEKLKR 662
+ L + + +N + KL++
Sbjct: 1003 HQQALDDLQAEEDKVNTLTKAKVKLEQ 1029
Score = 33.9 bits (76), Expect = 0.84
Identities = 29/143 (20%), Positives = 62/143 (43%), Gaps = 3/143 (2%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E A + K L+++ K + ++ L + +K E++ VK E+ L +
Sbjct: 931 EMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENK---VKNLTEEMAGLDE 987
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
+ ++L +E + + ++ DDL E +V L + + ++ +G E+E+
Sbjct: 988 IIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMD 1047
Query: 569 GMILKSLVESSIKSLQDPIASLD 591
K +E +K Q+ I L+
Sbjct: 1048 LERAKRKLEGDLKLTQESIMDLE 1070
>Hs7427513 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1046
Score = 39.3 bits (90), Expect = 0.020
Identities = 25/104 (24%), Positives = 59/104 (56%), Gaps = 6/104 (5%)
Query: 461 LQNDIMSFKNQYERDQ-VMLEQYDKRVQKLESELESVKEFKEKY-QSLAKLYSQLRQ--- 515
L+ ++S +++R+ V+ ++Y+K ++ ++E++ ++ EKY Q +A L +++Q
Sbjct: 545 LRERLLSASKEHQRESGVLRDKYEKALKAYQAEVDKLRAANEKYAQEVAGLKDKVQQATS 604
Query: 516 EHLNILKKMKKTQDDLA-EAESEVKKLKSSALSNVGIRNNNKGE 558
E++ ++ K D LA + + ++ LK++ S G + GE
Sbjct: 605 ENMGLMDNWKSKLDSLASDHQKSLEDLKATLNSGPGAQQKEIGE 648
>Hs4505301 [Z] KOG0161 Myosin class II heavy chain
Length = 1937
Score = 39.3 bits (90), Expect = 0.020
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 3/91 (3%)
Query: 452 ALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYS 511
A + +K + + +K +YE Q LE K + L +EL VK E +SL +L +
Sbjct: 1443 AALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYE--ESLDQLET 1500
Query: 512 QLRQEHLNILKKMKKTQDDLAEAESEVKKLK 542
LR+ H N+ +++ + +AE ++ +L+
Sbjct: 1501 -LRRAHKNLQQEISDLTEQIAEGGKQIHELE 1530
Score = 31.6 bits (70), Expect = 4.2
Identities = 34/166 (20%), Positives = 70/166 (41%), Gaps = 25/166 (15%)
Query: 451 EALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLY 510
E +Q+K LQ I + E ++ + +K+ L ELE + E E+
Sbjct: 1104 EIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQ 1163
Query: 511 SQLRQEHLNILKKMKKTQDDLAEAE-------SEVKKLKSSALSNVGIRNNN------KG 557
+L ++ +K+++ DL EA + ++K + +++ +G + +N K
Sbjct: 1164 VELNKKREAEFQKLRR---DLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKL 1220
Query: 558 ESEREEAKDRSGMI---------LKSLVESSIKSLQDPIASLDVSD 594
E E+ E K + + K +E +SL+D ++ L +
Sbjct: 1221 EKEKSELKMETDDLSSNAEAISKAKGHLEKMCRSLEDQVSGLKTKE 1266
Score = 31.6 bits (70), Expect = 4.2
Identities = 32/149 (21%), Positives = 69/149 (45%), Gaps = 2/149 (1%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
EK + ++ LQ + S + + EQ K +LE++++ V E E+ + +
Sbjct: 878 EKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINA 937
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
+ +++ + ++KK DDL ++V+K K + + V +N + + +E +
Sbjct: 938 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKQKHATENKV--KNLTEEMAGLDETIAKL 995
Query: 569 GMILKSLVESSIKSLQDPIASLDVSDLAT 597
K+L E+ ++L D A D ++ T
Sbjct: 996 SKEKKALQETHQQTLDDLQAEEDKVNILT 1024
>Hs20532997 [Z] KOG0161 Myosin class II heavy chain
Length = 975
Score = 39.3 bits (90), Expect = 0.020
Identities = 46/226 (20%), Positives = 94/226 (41%), Gaps = 18/226 (7%)
Query: 449 EKEALI---QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELES----VKEFKE 501
E +AL+ Q++ +L +++ KN YE V E + + L+ E+ + V+E +
Sbjct: 503 ESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTK 562
Query: 502 KYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESER 561
+ K+ + +E + +++T+ L ES++ + L K E ER
Sbjct: 563 NLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELL-------EAKAELER 615
Query: 562 E-EAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTI---VNILPE 617
+ KD + + +I SLQ + S S + ++ D+N + ++
Sbjct: 616 KLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANR 675
Query: 618 FVSLLLRCPQEMQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKRL 663
VS + ++Q +D L + Q +S + +A E+ L
Sbjct: 676 QVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSL 721
Score = 33.9 bits (76), Expect = 0.84
Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 17/105 (16%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLA 507
+ + A Q+ L+ I Q E D+ L + ++ KL+ ++++ K+ E ++ A
Sbjct: 871 IRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQA 930
Query: 508 KLYSQLRQEHLNILKKMKKTQDDLAE-------AESEVKKLKSSA 545
Y L K KK Q +L E AES+V KLK A
Sbjct: 931 NQY----------LSKYKKQQHELNEVKERAEVAESQVNKLKIKA 965
>Hs14702162 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1011
Score = 39.3 bits (90), Expect = 0.020
Identities = 25/104 (24%), Positives = 59/104 (56%), Gaps = 6/104 (5%)
Query: 461 LQNDIMSFKNQYERDQ-VMLEQYDKRVQKLESELESVKEFKEKY-QSLAKLYSQLRQ--- 515
L+ ++S +++R+ V+ ++Y+K ++ ++E++ ++ EKY Q +A L +++Q
Sbjct: 510 LRERLLSASKEHQRESGVLRDKYEKALKAYQAEVDKLRAANEKYAQEVAGLKDKVQQATS 569
Query: 516 EHLNILKKMKKTQDDLA-EAESEVKKLKSSALSNVGIRNNNKGE 558
E++ ++ K D LA + + ++ LK++ S G + GE
Sbjct: 570 ENMGLMDNWKSKLDSLASDHQKSLEDLKATLNSGPGAQQKEIGE 613
>Hs11024712 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 39.3 bits (90), Expect = 0.020
Identities = 32/117 (27%), Positives = 61/117 (51%), Gaps = 17/117 (14%)
Query: 479 LEQYDKRVQKLESELES--------VKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDD 530
+++ + RV++LESE+ES VK ++ + + +L Q ++ NIL+ QD
Sbjct: 1816 IQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILR----LQDL 1871
Query: 531 LAEAESEVKKLKSSA-----LSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKS 582
+ + +++VK K A SNV + K + E EEA++R+ + + + +KS
Sbjct: 1872 VDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAEERADIAESQVNKLRVKS 1928
Score = 35.4 bits (80), Expect = 0.29
Identities = 23/117 (19%), Positives = 53/117 (44%), Gaps = 4/117 (3%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVK-EFKEKYQSLAKLYSQ 512
+++ L ++ + E + LE + ++ +++ EL VK E K + Q
Sbjct: 1530 LEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQ 1589
Query: 513 LRQEHLNILKKMKKTQDDLAEAESE---VKKLKSSALSNVGIRNNNKGESEREEAKD 566
L++ HL +++ M+ T D + ++ +KK L+ + I+ N+ E ++
Sbjct: 1590 LKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRN 1646
>Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1530
Score = 39.3 bits (90), Expect = 0.020
Identities = 31/150 (20%), Positives = 75/150 (49%), Gaps = 10/150 (6%)
Query: 461 LQNDIMSFKNQYERD---QVMLEQYDKRVQKLESE-LESVKEFKEKYQSLAKLYSQLRQ- 515
+Q++ ++ +RD + +E Y++R+++LE E LE ++ +E Q++ L+ R
Sbjct: 419 MQSNTLTKDEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRAL 478
Query: 516 EHLNILKKMKKTQDDLAEAESEV---KKLKSSALSNVGIRNNNKGESEREEAKDRSGMIL 572
+ N K++KK +++ ++++ +L+ V +R + ++R ++ ++
Sbjct: 479 SNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVV 538
Query: 573 KSLVESSIKSLQDPIASLDVSDLATDLSNA 602
+ E K L + AS + A +L +A
Sbjct: 539 RQEKEELHKQLVE--ASERLKSQAKELKDA 566
>Hs20558376 [Z] KOG0161 Myosin class II heavy chain
Length = 1937
Score = 38.9 bits (89), Expect = 0.026
Identities = 25/91 (27%), Positives = 48/91 (52%), Gaps = 3/91 (3%)
Query: 452 ALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYS 511
A + +K + + +K +YE Q LE K + L +EL VK E +SL +L +
Sbjct: 1443 AALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYE--ESLDQLET 1500
Query: 512 QLRQEHLNILKKMKKTQDDLAEAESEVKKLK 542
LR+E+ N+ +++ + +AE ++ +L+
Sbjct: 1501 -LRRENKNLQQEISDLTEQIAEGGKQIHELE 1530
Score = 31.6 bits (70), Expect = 4.2
Identities = 34/166 (20%), Positives = 70/166 (41%), Gaps = 25/166 (15%)
Query: 451 EALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLY 510
E +Q+K LQ I + E ++ + +K+ L ELE + E E+
Sbjct: 1104 EIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQ 1163
Query: 511 SQLRQEHLNILKKMKKTQDDLAEAE-------SEVKKLKSSALSNVGIRNNN------KG 557
+L ++ +K+++ DL EA + ++K + +++ +G + +N K
Sbjct: 1164 VELNKKREAEFQKLRR---DLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKL 1220
Query: 558 ESEREEAKDRSGMI---------LKSLVESSIKSLQDPIASLDVSD 594
E E+ E K + + K +E +SL+D ++ L +
Sbjct: 1221 EKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKE 1266
Score = 31.2 bits (69), Expect = 5.4
Identities = 32/149 (21%), Positives = 69/149 (45%), Gaps = 2/149 (1%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
EK + ++ LQ + S + + EQ K +LE++++ V E E+ + +
Sbjct: 878 EKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINA 937
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
+ +++ + ++KK DDL ++V+K K + + V +N + + +E +
Sbjct: 938 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV--KNLTEEMAGLDETIAKL 995
Query: 569 GMILKSLVESSIKSLQDPIASLDVSDLAT 597
K+L E+ ++L D A D ++ T
Sbjct: 996 SKEKKALQETHQQTLDDLQAEEDKVNILT 1024
>Hs18375528 [A] KOG1295 Nonsense-mediated decay protein Upf3
Length = 483
Score = 38.5 bits (88), Expect = 0.034
Identities = 23/93 (24%), Positives = 45/93 (47%)
Query: 464 DIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKK 523
D + +YERDQ + + +R+++ E E KE EK ++ + ++++E + K
Sbjct: 344 DYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDK 403
Query: 524 MKKTQDDLAEAESEVKKLKSSALSNVGIRNNNK 556
KK + + SE + K + IRN ++
Sbjct: 404 GKKAESTESIGSSEKTEKKEEVVKRDRIRNKDR 436
>Hs12711674 [A] KOG1295 Nonsense-mediated decay protein Upf3
Length = 470
Score = 38.5 bits (88), Expect = 0.034
Identities = 23/93 (24%), Positives = 45/93 (47%)
Query: 464 DIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKK 523
D + +YERDQ + + +R+++ E E KE EK ++ + ++++E + K
Sbjct: 331 DYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDK 390
Query: 524 MKKTQDDLAEAESEVKKLKSSALSNVGIRNNNK 556
KK + + SE + K + IRN ++
Sbjct: 391 GKKAESTESIGSSEKTEKKEEVVKRDRIRNKDR 423
>CE02903 [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 751
Score = 38.5 bits (88), Expect = 0.034
Identities = 31/149 (20%), Positives = 71/149 (46%), Gaps = 8/149 (5%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKE----KYQSLAKL 509
+Q + A+L++ + + Q L YD ++++LES ++ KE KE + Q + +
Sbjct: 459 LQVELATLESTVKQLERQKGEATRRLADYDTQIEQLESACKAQKETKEDTEKRMQQIDED 518
Query: 510 YSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGE---SEREEAKD 566
N K+M++ + ++ +++ K ++ + R E ER+EA+D
Sbjct: 519 AKNAEDCKANDEKEMEELKKEIEMLDNQFKTVRGEIVKETSQREQKVAELTTLERKEARD 578
Query: 567 RSGM-ILKSLVESSIKSLQDPIASLDVSD 594
+ M L + +E++ K + +++ S+
Sbjct: 579 QIQMEKLDAAIENTTKLTEQVSDAVEKSE 607
>At5g57200 [TU] KOG0251 Clathrin assembly protein AP180 and related proteins
contain ENTH domain
Length = 591
Score = 38.5 bits (88), Expect = 0.034
Identities = 63/287 (21%), Positives = 117/287 (39%), Gaps = 41/287 (14%)
Query: 12 EEQTLEKSIKKALSGGDVAPKRKHVRACIVYTWDHKSSKTFFNLLKLQPYATDELQLFKA 71
E E+ ++K S V R V CI H SK L K + + K
Sbjct: 44 ESPPKERHVRKIFSATSVIQPRADVAYCI-----HALSK---RLSKTRNWVV----AMKV 91
Query: 72 LVLLHKVLQEGHPSALVEGIRNIDWIESLSRIFSVDSDDGSKYGSSRMRYIGDEYAKAIG 131
L+++H+ L+EG P+ E + N + RI + D + + + +
Sbjct: 92 LIVIHRTLREGDPT-FREELLNYSHRRHILRISNFKDDTSP---------LAWDCSAWVR 141
Query: 132 EYVFFLVEKLQFHKSHKGFNGIFEYE---EYVSLVSVSDPNEGYETVLDLMNLEDVADNL 188
Y FL E+L+ ++ + +Y+ E + S + +L +L + L
Sbjct: 142 TYALFLEERLECYR-------VLKYDIEAERLPKASGAASKTHRTRMLSGEDLLEQLPAL 194
Query: 189 QKLIFAGISNRKSGFGSFSSGLDCRGAVLIPLVSETYGIFKFVTS---MMKALYKQMGDY 245
Q+L++ I + G ++S+ L L+ + E++ I+ + + ++ +M +
Sbjct: 195 QQLLYRLIGCQPEG-AAYSNYLIQYALALV--LKESFKIYCAINDGIINLVDMFFEMSRH 251
Query: 246 DALSGL--FDRYTEQCARLNEFYFDCNTVQPLKNLITIPTLPSDPMS 290
DA+ L + R +Q L EFY C ++ +N PTL P S
Sbjct: 252 DAVKALNIYKRAGQQAENLAEFYDYCKGLELARN-FQFPTLRQPPPS 297
>YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1875
Score = 38.1 bits (87), Expect = 0.045
Identities = 30/120 (25%), Positives = 63/120 (52%), Gaps = 11/120 (9%)
Query: 453 LIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVK-EFKEKYQSLAKLYS 511
L+++ +L+N++ + N+ + Q L++ + V +ESEL ++K +EK Q L
Sbjct: 1218 LLRESNITLRNELENNNNKKKELQSELDKLKQNVAPIESELTALKYSMQEKEQELKLAKE 1277
Query: 512 QL---RQEHLNILKKMKK-TQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDR 567
++ ++ +IL+K ++ + D + ESE++ LK + N + +E EE +R
Sbjct: 1278 EVHRWKKRSQDILEKHEQLSSSDYEKLESEIENLKEE------LENKERQGAEAEEKFNR 1331
Score = 37.7 bits (86), Expect = 0.058
Identities = 43/187 (22%), Positives = 85/187 (44%), Gaps = 29/187 (15%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQS-LA 507
+K +L++++ +L N++ K E+++ + KR+ L++ + V+ K +Y+S L+
Sbjct: 967 DKISLLKEQMFNLNNELDLQKKGMEKEKA---DFKKRISILQNNNKEVEAVKSEYESKLS 1023
Query: 508 KL-----------------YSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSS--ALSN 548
K+ Y Q Q+H ++ K + + ++ L + +VK L S L N
Sbjct: 1024 KIQNDLDQQTIYANTAQNNYEQELQKHADVSKTISELREQLHTYKGQVKTLNLSRDQLEN 1083
Query: 549 VGIRNNNKGESERE---EAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFID 605
N S++E E D S ++ L S K L D I +D +++N+
Sbjct: 1084 ALKENEKSWSSQKESLLEQLDLSNSRIEDL-SSQNKLLYDQIQIYTAAD--KEVNNSTNG 1140
Query: 606 GDINTIV 612
+N I+
Sbjct: 1141 PGLNNIL 1147
Score = 36.6 bits (83), Expect = 0.13
Identities = 40/161 (24%), Positives = 74/161 (45%), Gaps = 33/161 (20%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQS--- 505
+KE L ++ ++ I S + E D V+ +Q + +VQ+ + ELE+ E+ +K Q
Sbjct: 1547 KKEELEKEFEEKVEERIKSMEQSGEIDVVLRKQLEAKVQEKQKELEN--EYNKKLQEELK 1604
Query: 506 ----------------LAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNV 549
A++ S+LR+E N L+ +KK D + ++ +K++ L
Sbjct: 1605 DVPHSSHISDDERDKLRAEIESRLREEFNNELQAIKKKSFDEGKQQA---MMKTTLLE-- 1659
Query: 550 GIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASL 590
R K ES+ E K + K S+ ++Q+P+ L
Sbjct: 1660 --RKLAKMESQLSETKQSAESPPK-----SVNNVQNPLLGL 1693
Score = 36.2 bits (82), Expect = 0.17
Identities = 51/232 (21%), Positives = 98/232 (41%), Gaps = 41/232 (17%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSL--AKLYS 511
+Q+K ++ S ++ + + + V LES+L +VKE + L AK+ +
Sbjct: 271 LQEKLLEIKGLSDSLNSEKQEFSAEMSLKQRLVDLLESQLNAVKEELNSIRELNTAKVIA 330
Query: 512 ----QLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDR 567
+ E+ ++LK+++ T++ LA+ E E +L S I + ++E AK
Sbjct: 331 DDSKKQTPENEDLLKELQLTKEKLAQCEKECLRLSS-------ITDEADEDNENLSAKSS 383
Query: 568 SGMI---------------LKSLVESSIKSLQDPIASLD-----VSDLATDLSNAFI--- 604
S I L++ +E+ I L+ + ++ L +L+NA +
Sbjct: 384 SDFIFLKKQLIKERRTKEHLQNQIETFIVELEHKVPIINSFKERTDMLENELNNAALLLE 443
Query: 605 --DGDINTIVNILPEFVSLLLRCPQEMQTIAE---DFLRCLSSAKQTDSVIN 651
+ N V L L+ C ++QT+ + D R + T+SV N
Sbjct: 444 HTSNEKNAKVKELNAKNQKLVECENDLQTLTKQRLDLCRQIQYLLITNSVSN 495
Score = 32.7 bits (73), Expect = 1.9
Identities = 34/134 (25%), Positives = 73/134 (54%), Gaps = 11/134 (8%)
Query: 462 QNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYS-QLRQEHLN- 519
QN I + K YE ++ ++KL+ +++S++ KE + +L++ + E +N
Sbjct: 845 QNKIEALKKDYESVITSVDSKQTDIEKLQYKVKSLE--KEIEEDKIRLHTYNVMDETIND 902
Query: 520 --ILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEA-KDRSGMILKSLV 576
+ K+++K++ +L +A S++K+ K L ++ + S+ +E+ KD + I K+L
Sbjct: 903 DSLRKELEKSKINLTDAYSQIKEYKD--LYETTSQSLQQTNSKLDESFKDFTNQI-KNLT 959
Query: 577 ESSIKSLQDPIASL 590
+ SL+D I+ L
Sbjct: 960 DEK-TSLEDKISLL 972
Score = 30.8 bits (68), Expect = 7.1
Identities = 27/127 (21%), Positives = 53/127 (41%), Gaps = 21/127 (16%)
Query: 448 MEKEALIQQKTAS-LQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSL 506
++K+ + +++T LQN I +F + E ++ + +R LE+EL +
Sbjct: 389 LKKQLIKERRTKEHLQNQIETFIVELEHKVPIINSFKERTDMLENELNNA---------- 438
Query: 507 AKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALS----------NVGIRNNNK 556
A L E +K++ L E E++++ L L + N++K
Sbjct: 439 ALLLEHTSNEKNAKVKELNAKNQKLVECENDLQTLTKQRLDLCRQIQYLLITNSVSNDSK 498
Query: 557 GESEREE 563
G +EE
Sbjct: 499 GPLRKEE 505
>CE28392 [U] KOG4809 Rab6 GTPase-interacting protein involved in
endosome-to-TGN transport
Length = 836
Score = 38.1 bits (87), Expect = 0.045
Identities = 33/159 (20%), Positives = 69/159 (42%), Gaps = 15/159 (9%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLR 514
+Q LQ D+ + + + + LEQ D+RV LE +L S K +L Q
Sbjct: 390 EQHNTLLQGDVDALRQKLDSKNKQLEQKDERVAALERDLSS---SKADVSDKGELIRQTE 446
Query: 515 QEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGI-------RNNNKGESEREEAKDR 567
+ ++ ++ + + E E E+ + K LS+ + +GE ER+ +
Sbjct: 447 MKTSQLIGRVDSLETTVREKEQELDRAKIRLLSHPDVVKEKEMTEKIEQGERERQRLAEH 506
Query: 568 SGMILKSLVESSI---KSLQDPIASL--DVSDLATDLSN 601
+ ++ + ++ K+ Q+ + L + +L +LS+
Sbjct: 507 IDQVRRNAEKDAMEQQKTYQNEMTQLKATIENLQKELSD 545
>7303314 [S] KOG0992 Uncharacterized conserved protein
Length = 611
Score = 38.1 bits (87), Expect = 0.045
Identities = 35/155 (22%), Positives = 73/155 (46%), Gaps = 9/155 (5%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQV-MLEQYDKRVQKLESELESVKEFKEKYQSLA 507
EK +QQ +++SF+ Q D++ ++ Q ++++ L ELE ++ + + L
Sbjct: 119 EKIQNLQQIEIDKLKNLLSFREQESVDRMGLMRQQTQQIESLSEELERLRPIESVAEDLR 178
Query: 508 KLYSQLR---QEHLNIL-KKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREE 563
QLR Q+ N+L + Q++ + +K ++ S L ++G N+ ++ +
Sbjct: 179 DELEQLRHSTQQEKNLLTTTLAAVQEENRHLKKRMKIVEESRLESLGKLNS----EQQVQ 234
Query: 564 AKDRSGMILKSLVESSIKSLQDPIASLDVSDLATD 598
A R +L+ +E + L D S +LA +
Sbjct: 235 ALIREHKLLEQHLEEAHLQLSDIKGSWSGQNLALE 269
>YNL079c [Z] KOG1003 Actin filament-coating protein tropomyosin
Length = 199
Score = 37.7 bits (86), Expect = 0.058
Identities = 42/178 (23%), Positives = 75/178 (41%), Gaps = 35/178 (19%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVK-------EFKE 501
EK +++K L+ + + +NQ + V +Q + ++KLE+ L K E +
Sbjct: 20 EKYEELKEKNKDLEQENVEKENQIKSLTVKNQQLEDEIEKLEAGLSDSKQTEQDNVEKEN 79
Query: 502 KYQSLAKLYSQLRQE-------------------HL-----NILKKMKKTQDDLAEAESE 537
+ +SL QL +E HL N KK ++ ++DL E++++
Sbjct: 80 QIKSLTVKNHQLEEEIEKLEAELAESKQLSEDSHHLQSNNDNFSKKNQQLEEDLEESDTK 139
Query: 538 VK----KLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLD 591
+K KL+ S L + E+ E +R L E + K L + ASL+
Sbjct: 140 LKETTEKLRESDLKADQLERRVAALEEQREEWERKNEELTVKYEDAKKELDEIAASLE 197
Score = 32.3 bits (72), Expect = 2.4
Identities = 24/108 (22%), Positives = 53/108 (48%), Gaps = 8/108 (7%)
Query: 483 DKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLK 542
DK +KL + + ++EKY+ L + L QE++ ++K + E E++KL+
Sbjct: 2 DKIREKLSNLKLEAESWQEKYEELKEKNKDLEQENVEKENQIKSLTVKNQQLEDEIEKLE 61
Query: 543 SSALSNVGIRNNNKGESEREEAKD--RSGMILKSLVESSIKSLQDPIA 588
+ G+ ++ + E + E ++ +S + +E I+ L+ +A
Sbjct: 62 A------GLSDSKQTEQDNVEKENQIKSLTVKNHQLEEEIEKLEAELA 103
>Hs4885399 [D] KOG0964 Structural maintenance of chromosome protein 3 (sister
chromatid cohesion complex Cohesin subunit SMC3)
Length = 1217
Score = 37.7 bits (86), Expect = 0.058
Identities = 46/191 (24%), Positives = 90/191 (47%), Gaps = 18/191 (9%)
Query: 482 YDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKL 541
YD R +LE + + K +E + AKL LR+ I ++ + + + + E++ +K
Sbjct: 669 YDTRKSRLELQKDVRKAEEELGELEAKLNENLRRNIERINNEIDQLMNQMQQIETQQRKF 728
Query: 542 KS---SALSNVGIRNNNKGESERE-EAKDRSGMILKSLVESSIKSLQDPIASLDVSDLAT 597
K+ S LS + + + +SE+ K RS L+SL E+S+ +++ SL ++L T
Sbjct: 729 KASRDSILSEMKMLKEKRQQSEKTFMPKQRS---LQSL-EASLHAMESTRESLK-AELGT 783
Query: 598 DLSNAFIDGDINTIVNILPEFVSLLLRCPQEMQTIAEDFLRCLSSAKQTDSVINANIAFQ 657
DL + D + + E L QE + + + ++ + ++ +N N+
Sbjct: 784 DLLSQLSLEDQKRVDALNDEIRQL----QQENRQLLNERIKLEGIITRVETYLNENLR-- 837
Query: 658 EKLKRLGEIRQ 668
KRL ++ Q
Sbjct: 838 ---KRLDQVEQ 845
Score = 33.5 bits (75), Expect = 1.1
Identities = 33/140 (23%), Positives = 65/140 (45%), Gaps = 8/140 (5%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
I+++ L+ I + K + E+ ++ K+ KLE + K+ +++ ++ +L
Sbjct: 270 IERQVRELKTKISAMKEEKEQLSAERQEQIKQRTKLELKA---KDLQDELAGNSEQRKRL 326
Query: 514 RQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREE--AKDRSGMI 571
+E +L+K+++ Q +LAE E + +K GI + ER + AK G
Sbjct: 327 LKERQKLLEKIEEKQKELAETEPKFNSVKEK--EERGIARLAQATQERTDLYAKQGRGSQ 384
Query: 572 LKSLVESSIKSLQDPIASLD 591
S E K ++ + SLD
Sbjct: 385 FTSKEERD-KWIKKELKSLD 403
Score = 31.2 bits (69), Expect = 5.4
Identities = 24/91 (26%), Positives = 51/91 (55%), Gaps = 5/91 (5%)
Query: 451 EALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLY 510
E +++T+ ++ + Q RD+ +E +++V++L++++ ++KE EK Q A+
Sbjct: 241 ELSAKRETSGEKSRQLRDAQQDARDK--MEDIERQVRELKTKISAMKE--EKEQLSAERQ 296
Query: 511 SQLRQEHLNILKKMKKTQDDLAEAESEVKKL 541
Q++Q + K K QD+LA + K+L
Sbjct: 297 EQIKQ-RTKLELKAKDLQDELAGNSEQRKRL 326
Score = 30.8 bits (68), Expect = 7.1
Identities = 20/86 (23%), Positives = 40/86 (46%), Gaps = 3/86 (3%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLR 514
+++ A++ D+ + E++ LEQY+K Q L V+E KY + +L+
Sbjct: 410 KRQIAAIHKDLEDTEANKEKN---LEQYNKLDQDLNEVKARVEELDRKYYEVKNKKDELQ 466
Query: 515 QEHLNILKKMKKTQDDLAEAESEVKK 540
E + ++ Q LA +++K
Sbjct: 467 SERNYLWREENAEQQALAAKREDLEK 492
>Hs22035581 [D] KOG3859 Septins (P-loop GTPases)
Length = 429
Score = 37.7 bits (86), Expect = 0.058
Identities = 31/115 (26%), Positives = 59/115 (50%), Gaps = 11/115 (9%)
Query: 457 KTASLQNDIMSFKNQY-----ERDQVMLEQYDKRVQKLESEL-ESVKEFKEKYQSLAKLY 510
K SLQ + +N++ ++++ M + + +RV++ E+EL E+ KE EK+ L KL+
Sbjct: 316 KPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLH 375
Query: 511 SQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAK 565
Q+ L+ KK+ DD A + +K + L + G + +R++ K
Sbjct: 376 ----QDEKKKLEDKKKSLDDEVNAFKQ-RKTAAELLQSQGSQAGGSQTLKRDKEK 425
>Hs22035577 [D] KOG3859 Septins (P-loop GTPases)
Length = 427
Score = 37.7 bits (86), Expect = 0.058
Identities = 31/115 (26%), Positives = 59/115 (50%), Gaps = 11/115 (9%)
Query: 457 KTASLQNDIMSFKNQY-----ERDQVMLEQYDKRVQKLESEL-ESVKEFKEKYQSLAKLY 510
K SLQ + +N++ ++++ M + + +RV++ E+EL E+ KE EK+ L KL+
Sbjct: 316 KPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLH 375
Query: 511 SQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAK 565
Q+ L+ KK+ DD A + +K + L + G + +R++ K
Sbjct: 376 ----QDEKKKLEDKKKSLDDEVNAFKQ-RKTAAELLQSQGSQAGGSQTLKRDKEK 425
>Hs21361478 [D] KOG3859 Septins (P-loop GTPases)
Length = 434
Score = 37.7 bits (86), Expect = 0.058
Identities = 31/115 (26%), Positives = 59/115 (50%), Gaps = 11/115 (9%)
Query: 457 KTASLQNDIMSFKNQY-----ERDQVMLEQYDKRVQKLESEL-ESVKEFKEKYQSLAKLY 510
K SLQ + +N++ ++++ M + + +RV++ E+EL E+ KE EK+ L KL+
Sbjct: 316 KPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLH 375
Query: 511 SQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAK 565
Q+ L+ KK+ DD A + +K + L + G + +R++ K
Sbjct: 376 ----QDEKKKLEDKKKSLDDEVNAFKQ-RKTAAELLQSQGSQAGGSQTLKRDKEK 425
>CE18407 [O] KOG4185 Predicted E3 ubiquitin ligase
Length = 244
Score = 37.7 bits (86), Expect = 0.058
Identities = 30/103 (29%), Positives = 57/103 (55%), Gaps = 10/103 (9%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVK-EFKEKYQSLAK 508
K+AL+ Q+ + + +N+Y D LE+ ++R++ L+ EL+ ++ + + +SL +
Sbjct: 69 KQALMNQQMITQH---LKKRNEYLDD---LEEANERIKILDEELDKLEAKISKTEESLVQ 122
Query: 509 LYSQL--RQEHLNILKKMKKTQDDLAEA-ESEVKKLKSSALSN 548
S L + E L ++K K DD A + E+ +LK+S L N
Sbjct: 123 SVSMLLEKDEQLKTIRKEMKIMDDERSAFDQELTRLKTSRLEN 165
>YIL149c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1679
Score = 37.4 bits (85), Expect = 0.076
Identities = 41/208 (19%), Positives = 91/208 (43%), Gaps = 18/208 (8%)
Query: 461 LQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNI 520
L+ + F Q E+ + +E+ K ++K+E V+ K+K S Y +E+ ++
Sbjct: 958 LKEGALHFVQQSEKLRNEVERIQKMIEKIEKMSTIVQLCKKKEMS---QYQSTMKENKDL 1014
Query: 521 LKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSI 580
+ + + + D A+ ++E+ K KSS S + + ++ EE D ++ ++ ++
Sbjct: 1015 SELVIRLEKDAADCQAELTKTKSSLYSAQDLLDKHE-RKWMEEKADYERELISNIEQTES 1073
Query: 581 KSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCPQEMQTIAEDFLRC- 639
+++ + V D A + +GD + + + VSL E ++ C
Sbjct: 1074 LRVENSVLIEKVDDTAAN------NGDKDHL-----KLVSLFSNLRHERNSLETKLTTCK 1122
Query: 640 --LSSAKQTDSVINANIAFQEKLKRLGE 665
L+ KQ + + I ++ + L E
Sbjct: 1123 RELAFVKQKNDSLEKTINDLQRTQTLSE 1150
Score = 36.6 bits (83), Expect = 0.13
Identities = 39/177 (22%), Positives = 78/177 (44%), Gaps = 27/177 (15%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESEL------ESVKEFKEK 502
EK+ +I ++T + + N+ + +Y K ++ L+ E E+++ KE
Sbjct: 1395 EKDRIIDERTKEFEKKLQETLNKSTSSEA---EYSKDIETLKKEWLKEYEDETLRRIKEA 1451
Query: 503 YQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESERE 562
++L K +E + K + K +++L E KKLK +A S + N GE E
Sbjct: 1452 EENLKKRIRLPSEERIQ--KIISKRKEELEEEFR--KKLKENAGSLTFLDNKGSGEDAEE 1507
Query: 563 E-----AKDRS-------GMILKSLV--ESSIKSLQDPIASLDVSDLATDLSNAFID 605
E +K S G I + + + +K++++ ++ D + T+ N +D
Sbjct: 1508 ELWNSPSKGNSERPSAVAGFINQKNLKPQEQLKNVKNDVSFNDSQSMVTNKENNIVD 1564
>HsM14719396 [D] KOG3859 Septins (P-loop GTPases)
Length = 434
Score = 37.4 bits (85), Expect = 0.076
Identities = 33/115 (28%), Positives = 58/115 (49%), Gaps = 13/115 (11%)
Query: 457 KTASLQNDIMSFKNQY-----ERDQVMLEQYDKRVQKLESEL-ESVKEFKEKYQSLAKLY 510
K SLQ + +N++ ++++ M + + +RV++ E+EL E+ KE EK+ L KL+
Sbjct: 316 KPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLH 375
Query: 511 SQLRQEHLNILKKMKKTQDDLAEAESEVK---KLKSSALSNVGIRNNNKGESERE 562
Q+ L+ KK+ DD A + K +L S S G K + E++
Sbjct: 376 ----QDEKKKLEDKKKSLDDEVNAFKQRKTAAELPQSQGSQAGGSQTLKRDKEKK 426
>Hs5453642 [D] KOG0018 Structural maintenance of chromosome protein 1 (sister
chromatid cohesion complex Cohesin subunit SMC1)
Length = 1233
Score = 37.4 bits (85), Expect = 0.076
Identities = 40/186 (21%), Positives = 82/186 (43%), Gaps = 39/186 (20%)
Query: 469 KNQYERDQVMLEQYDKRVQKLESELESVKEFKEKY-----QSLAKLYSQLRQEHL----- 518
KNQ + DQ + +++ V+K E+E+E +K+ ++++ +++A+L L+ +HL
Sbjct: 825 KNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQL-QDLKNQHLAKKSE 883
Query: 519 ---------NILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNN--------------N 555
I KK+ ++ + EV +++ R+N +
Sbjct: 884 VNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLS 943
Query: 556 KGE----SEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTI 611
KG S+ E + + S SSI + ++ + +D DL DL +A + +I
Sbjct: 944 KGTMDDISQEEGSSQGEDSVSGSQRISSIYA-REALIEIDYGDLCEDLKDAQAEEEIKQE 1002
Query: 612 VNILPE 617
+N L +
Sbjct: 1003 MNTLQQ 1008
Score = 32.0 bits (71), Expect = 3.2
Identities = 35/167 (20%), Positives = 67/167 (39%), Gaps = 35/167 (20%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVK----------- 497
E E +++++ S D+ +NQ ++ + E+ KR L ELE
Sbjct: 349 EFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLD 408
Query: 498 -EFKEKYQSLAKLYSQLRQEHLN----------------ILKKMKKTQDDLAEAE----- 535
E ++K ++ AK+ +LR+ N L++ KK + +L E
Sbjct: 409 LEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKR 468
Query: 536 --SEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSI 580
E+ K + + +G ++ ES R++ K +K L S+
Sbjct: 469 RIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSV 515
Score = 30.8 bits (68), Expect = 7.1
Identities = 22/93 (23%), Positives = 46/93 (48%), Gaps = 4/93 (4%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESV-KEFKEKYQSLAKL--- 509
+ ++ AS +I K + ++ + L++ K + K+ E + + KE KEK L +
Sbjct: 238 LNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQ 297
Query: 510 YSQLRQEHLNILKKMKKTQDDLAEAESEVKKLK 542
Y + ++ + +KK++ + L A+ KK K
Sbjct: 298 YIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRK 330
>Hs4506751 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1427
Score = 37.4 bits (85), Expect = 0.076
Identities = 27/94 (28%), Positives = 52/94 (54%), Gaps = 5/94 (5%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E + I++ Q++I + +NQ + ++ + K ++ L ++L +K KEK SL
Sbjct: 647 ELKTQIEKMRLDYQHEIENLQNQQDSERAA---HAKEMEALRAKL--MKVIKEKENSLEA 701
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLK 542
+ S+L + L +M+ T + L EAE +VK+L+
Sbjct: 702 IRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELE 735
>Hs4505987 [R] KOG1899 LAR transmembrane tyrosine phosphatase-interacting
protein liprin
Length = 1005
Score = 37.4 bits (85), Expect = 0.076
Identities = 33/143 (23%), Positives = 67/143 (46%), Gaps = 15/143 (10%)
Query: 451 EALIQQKT---ASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLA 507
E ++QQ+ SL+ + + ++ L +K E + + ++ L
Sbjct: 152 EEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLR 211
Query: 508 KLYSQLRQEHLNILKKMKKTQDDLA-------EAESEVKKLKSSALSNV---GIRNNNKG 557
S++ E L KK+K T+D+LA E ESEVK+L+ + + G+ ++
Sbjct: 212 LKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRD 271
Query: 558 ESEREEAKDRSGMI--LKSLVES 578
E+ +++ K+++ + +K VES
Sbjct: 272 ENFKKKLKEKNIEVQKMKKAVES 294
>Hs14764231 [D] KOG0018 Structural maintenance of chromosome protein 1 (sister
chromatid cohesion complex Cohesin subunit SMC1)
Length = 1233
Score = 37.4 bits (85), Expect = 0.076
Identities = 40/186 (21%), Positives = 82/186 (43%), Gaps = 39/186 (20%)
Query: 469 KNQYERDQVMLEQYDKRVQKLESELESVKEFKEKY-----QSLAKLYSQLRQEHL----- 518
KNQ + DQ + +++ V+K E+E+E +K+ ++++ +++A+L L+ +HL
Sbjct: 825 KNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQL-QDLKNQHLAKKSE 883
Query: 519 ---------NILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNN--------------N 555
I KK+ ++ + EV +++ R+N +
Sbjct: 884 VNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLS 943
Query: 556 KGE----SEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTI 611
KG S+ E + + S SSI + ++ + +D DL DL +A + +I
Sbjct: 944 KGTMDDISQEEGSSQGEDSVSGSQRISSIYA-REALIEIDYGDLCEDLKDAQAEEEIKQE 1002
Query: 612 VNILPE 617
+N L +
Sbjct: 1003 MNTLQQ 1008
Score = 32.0 bits (71), Expect = 3.2
Identities = 35/167 (20%), Positives = 67/167 (39%), Gaps = 35/167 (20%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVK----------- 497
E E +++++ S D+ +NQ ++ + E+ KR L ELE
Sbjct: 349 EFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLD 408
Query: 498 -EFKEKYQSLAKLYSQLRQEHLN----------------ILKKMKKTQDDLAEAE----- 535
E ++K ++ AK+ +LR+ N L++ KK + +L E
Sbjct: 409 LEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKR 468
Query: 536 --SEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSI 580
E+ K + + +G ++ ES R++ K +K L S+
Sbjct: 469 RIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSV 515
Score = 30.8 bits (68), Expect = 7.1
Identities = 22/93 (23%), Positives = 46/93 (48%), Gaps = 4/93 (4%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESV-KEFKEKYQSLAKL--- 509
+ ++ AS +I K + ++ + L++ K + K+ E + + KE KEK L +
Sbjct: 238 LNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQ 297
Query: 510 YSQLRQEHLNILKKMKKTQDDLAEAESEVKKLK 542
Y + ++ + +KK++ + L A+ KK K
Sbjct: 298 YIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRK 330
>CE21149 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC
superfamily
Length = 1298
Score = 37.4 bits (85), Expect = 0.076
Identities = 32/140 (22%), Positives = 64/140 (44%), Gaps = 10/140 (7%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVK-EFKEKYQSLA 507
+K +I + A LQ+++ + + + +V ++ KLE E+E +K + K+ + A
Sbjct: 400 DKARMIAKNCAELQSNLRTAQEAATKIEVEMKTLQNEKVKLEKEVEQLKFKIKQGQNATA 459
Query: 508 KLYSQLRQEHLNILKKMKKTQDDL----AEAESEVKKLKSSALSNVGIRNNNKGESEREE 563
+ L++E + ++K+ DL A +E K + L + I E+E+
Sbjct: 460 GMKDLLKKE-----EALRKSLADLPLLDENALTECKLKREKYLKQLDILKKKCAEAEKNA 514
Query: 564 AKDRSGMILKSLVESSIKSL 583
KDR LK + + K +
Sbjct: 515 EKDREKESLKQTLSIARKKM 534
Score = 34.3 bits (77), Expect = 0.64
Identities = 42/225 (18%), Positives = 98/225 (42%), Gaps = 16/225 (7%)
Query: 461 LQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNI 520
++ D+ + ++ + M QY K+ + L ++ +K + +++ + ++ ++ N+
Sbjct: 575 MEEDLRDVQLNVQKLETMQHQYRKQEESLTAQ--ELKLSENIFEACSCEAEEVSEKLENL 632
Query: 521 LKKMKKTQDDLAEA-------ESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILK 573
K++KK + DLA +S +++ KSS + R+ + E +K M L
Sbjct: 633 RKRLKKARKDLAPLSAKSNLYDSYIEESKSSGCCPLCDRDFKTKKEINEFSKKLENMTLS 692
Query: 574 SLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCPQEMQTIA 633
E + L+ ++ L+ ++ +G N + I+ E + + + +A
Sbjct: 693 FPTEQ--EELEKLVSKLEKEEIII----VKAEGQANELQRIVKELKEVREKNRKLSTEMA 746
Query: 634 EDFLRCLSSAKQTDSVINANIAFQEKLKRLGEIRQYSYRYGDSDE 678
E+ + KQ ++V NA + E L+ + Q Y + +E
Sbjct: 747 EEKSNLSKNEKQLETV-NAKLKLAEDLQTDVGVIQQLYEQTEENE 790
Score = 31.2 bits (69), Expect = 5.4
Identities = 20/104 (19%), Positives = 53/104 (50%), Gaps = 8/104 (7%)
Query: 462 QNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNIL 521
Q ++ ++ E++++++ + + + +L+ ++ +KE +EK + KL +++ +E N+
Sbjct: 697 QEELEKLVSKLEKEEIIIVKAEGQANELQRIVKELKEVREKNR---KLSTEMAEEKSNLS 753
Query: 522 KKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAK 565
K K+ E + KL ++VG+ ++E E +
Sbjct: 754 KNEKQ-----LETVNAKLKLAEDLQTDVGVIQQLYEQTEENEKR 792
>7296950 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein) and related
proteins
Length = 7182
Score = 37.4 bits (85), Expect = 0.076
Identities = 45/214 (21%), Positives = 82/214 (38%), Gaps = 29/214 (13%)
Query: 462 QNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLR------- 514
Q I S E Q + + +KRV ++ ELE V E+ + +L L ++ R
Sbjct: 6280 QQKIKSLMKDAEAKQSLADVLEKRVANMQQELEPV-EYSQLESALRNLNTENRNLSGVLK 6338
Query: 515 ---QEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMI 571
L K K ++DL +A +K S E E++ ++R
Sbjct: 6339 AELDRALEASKARKSLENDLDKARQWLKTKISEVRKLPVYHPLTSAEIEKKIQENRK--- 6395
Query: 572 LKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCPQEMQT 631
+ K D + + DV A ++ D D + IL E + + QT
Sbjct: 6396 ----YDDDAKQFNDSVLT-DVQRQAANIMKDCDDADKAALQQILDEIAA-------DYQT 6443
Query: 632 IAEDFLRCLSSAKQTDSVINANIAFQEKLKRLGE 665
+ ++ + K D ++ AF++ +K +G+
Sbjct: 6444 LKDESSK---RGKSLDDLLQGRKAFEDSMKNMGD 6474
Score = 36.2 bits (82), Expect = 0.17
Identities = 31/134 (23%), Positives = 62/134 (46%), Gaps = 17/134 (12%)
Query: 461 LQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKY----QSLAKLYSQLRQE 516
L +DI + K++Y R + D RV L ++ K+ K + Q L + +LR+
Sbjct: 6538 LNDDIKNMKDRYGR---IKNTIDDRVNALGDHIKKYKDAKSRLAECSQFLGNIQQKLREL 6594
Query: 517 HLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLV 576
+ I +++ QD L E +K+LK S + G+ + ++ + ++ +
Sbjct: 6595 NRPIGSRIEDVQDLLGAYEGILKELKDS--------KSKMGDMQMDDLPELQSILAQQ-- 6644
Query: 577 ESSIKSLQDPIASL 590
+ IK ++D +A L
Sbjct: 6645 DDMIKLIEDQLAHL 6658
Score = 34.3 bits (77), Expect = 0.64
Identities = 45/211 (21%), Positives = 91/211 (42%), Gaps = 10/211 (4%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
+Q + L+ND + E++ Y + +Q +E L + + SL +
Sbjct: 5714 LQSRCDKLKNDCSAHITALEQEMFDYNAYHQSLQDVEKWLLQISFQLMAHNSLFISNREQ 5773
Query: 514 RQE----HLNILKKMKKTQ---DDL-AEAESEVKKLKSSALS-NVGIRNNNKGESEREEA 564
QE H +L +++K Q DDL A+ ++++K+ +SS + + + K + +
Sbjct: 5774 TQEQIKQHEALLVEIQKYQTNLDDLNAKGQAQIKRYESSTPAIRPTVESQLKNIQDSYNS 5833
Query: 565 KDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLR 624
++ + +K+ + S+ Q+ +LD + I +++ L E LR
Sbjct: 5834 LLQTSVQIKNRLLESLAKFQEYEDTLDSIMRNLETYEPIIQTELDAPATSL-ELAQNQLR 5892
Query: 625 CPQEMQTIAEDFLRCLSSAKQTDSVINANIA 655
C QEMQ + L++A Q A+I+
Sbjct: 5893 CAQEMQNKLNNEKSRLAAAVQACEAATASIS 5923
Score = 33.9 bits (76), Expect = 0.84
Identities = 41/173 (23%), Positives = 71/173 (40%), Gaps = 23/173 (13%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQ----------YDKRVQKLESELESVKEFKEKYQ 504
QQ+ S+ ND+++ +R Q+MLE D + KLESEL K+ Q
Sbjct: 6074 QQELVSM-NDLLNSIGD-KRSQLMLEMTGSLGDEDTDLDDNIDKLESELMDAIAKKQAGQ 6131
Query: 505 SLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEA 564
++ Y Q + N + K D L K +A++ + +G + +E
Sbjct: 6132 NVIDGYRQGMADVQNWFDTLIKRMDVLDRGSGLNCAQKMAAINEIKNEYELQGHPKIQEL 6191
Query: 565 KDRSGMILKSL-------VESSIKSLQDPIASL----DVSDLATDLSNAFIDG 606
K ++ + + + VE +KSL A L D D++N ++G
Sbjct: 6192 KGKAAQVAEVISNLDGQQVEEQMKSLDRRFADLGKRIDRKSQLLDVTNKGVEG 6244
>HsM4885113 [BD] KOG0996 Structural maintenance of chromosome protein 4
(chromosome condensation complex Condensin subunit C)
Length = 1288
Score = 37.0 bits (84), Expect = 0.099
Identities = 34/131 (25%), Positives = 64/131 (47%), Gaps = 15/131 (11%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
I +K+ L N+ M KN+ +D +K++ K+ +E E KEK+ L Q+
Sbjct: 351 INEKSNILSNE-MKAKNKDVKDT------EKKLNKITKFIE---ENKEKFTQLDLEDVQV 400
Query: 514 RQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRN-----NNKGESEREEAKDRS 568
R++ + K KK + L + + +V++ KS + I N NN E E+E+ + +
Sbjct: 401 REKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKL 460
Query: 569 GMILKSLVESS 579
++ SL + +
Sbjct: 461 KEVMDSLKQET 471
Score = 35.8 bits (81), Expect = 0.22
Identities = 54/251 (21%), Positives = 98/251 (38%), Gaps = 43/251 (17%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQ--SLAKLYSQ 512
++K L+ ++ +FK +Y+ + + V++L + + + K K Q L K+ Q
Sbjct: 853 KKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLKAQQDKLDKINKQ 912
Query: 513 L------------------------RQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSN 548
L + L K++K T+ ++ + +E+K L+ A
Sbjct: 913 LDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSLEDKAAEV 972
Query: 549 VGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDI 608
V +N N E E + +L+ L K +Q+ +L L+ L IDG I
Sbjct: 973 V--KNTNAAEESLPEIQKEHRNLLQEL-----KVIQENEHALQKDALSIKLKLEQIDGHI 1025
Query: 609 ---NTIVNILPEFVSLLLRCPQEMQTIAEDFL---RCLSSAKQTDSVINANIAFQ----E 658
N+ + + +S + P E I E + L + K DS+ N + E
Sbjct: 1026 AEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLEARCHE 1085
Query: 659 KLKRLGEIRQY 669
LG I +Y
Sbjct: 1086 MKPNLGAIAEY 1096
>Hs4505257 [R] KOG3529 Radixin moesin and related proteins of the ERM family
Length = 577
Score = 37.0 bits (84), Expect = 0.099
Identities = 34/147 (23%), Positives = 71/147 (48%), Gaps = 19/147 (12%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
+QQ A + + K+Q + ++ MLE K+ + E E E ++ KE+ L + Q+
Sbjct: 302 VQQMKAQAREE----KHQKQMERAMLENEKKKREMAEKEKEKIEREKEE---LMERLKQI 354
Query: 514 RQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILK 573
++ +++++ E E E K+ +S A K ER+EA++ +L+
Sbjct: 355 EEQTKKAQQELEEQTRRALELEQERKRAQSEA---------EKLAKERQEAEEAKEALLQ 405
Query: 574 SLVESSIKSLQDPIASLDVSDLATDLS 600
+ + K Q+ +A L++++L +S
Sbjct: 406 ASRDQ--KKTQEQLA-LEMAELTARIS 429
>Hs21361252 [BD] KOG0996 Structural maintenance of chromosome protein 4
(chromosome condensation complex Condensin subunit C)
Length = 1288
Score = 37.0 bits (84), Expect = 0.099
Identities = 34/131 (25%), Positives = 64/131 (47%), Gaps = 15/131 (11%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
I +K+ L N+ M KN+ +D +K++ K+ +E E KEK+ L Q+
Sbjct: 351 INEKSNILSNE-MKAKNKDVKDT------EKKLNKITKFIE---ENKEKFTQLDLEDVQV 400
Query: 514 RQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRN-----NNKGESEREEAKDRS 568
R++ + K KK + L + + +V++ KS + I N NN E E+E+ + +
Sbjct: 401 REKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKL 460
Query: 569 GMILKSLVESS 579
++ SL + +
Sbjct: 461 KEVMDSLKQET 471
Score = 35.8 bits (81), Expect = 0.22
Identities = 54/251 (21%), Positives = 98/251 (38%), Gaps = 43/251 (17%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQ--SLAKLYSQ 512
++K L+ ++ +FK +Y+ + + V++L + + + K K Q L K+ Q
Sbjct: 853 KKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLKAQQDKLDKINKQ 912
Query: 513 L------------------------RQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSN 548
L + L K++K T+ ++ + +E+K L+ A
Sbjct: 913 LDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSLEDKAAEV 972
Query: 549 VGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDI 608
V +N N E E + +L+ L K +Q+ +L L+ L IDG I
Sbjct: 973 V--KNTNAAEESLPEIQKEHRNLLQEL-----KVIQENEHALQKDALSIKLKLEQIDGHI 1025
Query: 609 ---NTIVNILPEFVSLLLRCPQEMQTIAEDFL---RCLSSAKQTDSVINANIAFQ----E 658
N+ + + +S + P E I E + L + K DS+ N + E
Sbjct: 1026 AEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLEARCHE 1085
Query: 659 KLKRLGEIRQY 669
LG I +Y
Sbjct: 1086 MKPNLGAIAEY 1096
>CE20131 [T] KOG0976 Rho/Rac1-interacting serine/threonine kinase Citron
Length = 1256
Score = 37.0 bits (84), Expect = 0.099
Identities = 26/105 (24%), Positives = 52/105 (48%), Gaps = 5/105 (4%)
Query: 480 EQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVK 539
E +R +L S ++++E K + L ++ ++RQ +L++ K + +AEA +++
Sbjct: 528 EADSQRDSELRSAKKTIQEVKADNKKLQQILEEVRQNQSKVLEENVKLRKGMAEAIEKIE 587
Query: 540 KLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQ 584
+ K + S + GE + EAK+ +LK E K L+
Sbjct: 588 EFKRNWHS-----SREAGERLQLEAKENEEKVLKVEEELQEKRLE 627
Score = 30.4 bits (67), Expect = 9.3
Identities = 22/101 (21%), Positives = 50/101 (48%), Gaps = 4/101 (3%)
Query: 456 QKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQ 515
Q+T + D+ ++ ++ + + R +LE+E + +++ YQ K +++R
Sbjct: 85 QETRIYRRDVTLLEDDLKQKESQIRILQNRCLRLETEKQKMQDTISGYQEDLK-ENEIRI 143
Query: 516 EHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNK 556
E+LN ++ K +D+L+ E+ + L N ++ N K
Sbjct: 144 ENLN--SRLHKLEDELSAKTHEIFSI-GEELKNKTMKLNEK 181
>SPBC29A10.04 [D] KOG0018 Structural maintenance of chromosome protein 1 (sister
chromatid cohesion complex Cohesin subunit SMC1)
Length = 1233
Score = 36.6 bits (83), Expect = 0.13
Identities = 37/138 (26%), Positives = 64/138 (45%), Gaps = 22/138 (15%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
IQ+K A ++ D DQ +Q LE++L S+ ++++ L
Sbjct: 325 IQRKAAEIEKDYS--------DQA------STLQVLENQLTSLSAAEKEF-----LKDMQ 365
Query: 514 RQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILK 573
+E L L+ + + +++ SE KL S+ L + N N + ++KD I+
Sbjct: 366 EKEQLKGLRLLPEDKEEYEGLRSEADKLNSNLLFKLQTLNRNIKVTS--QSKDSLTSIVG 423
Query: 574 SLVESSIKSLQDPIASLD 591
L ES IKSL + ++SLD
Sbjct: 424 DL-ESKIKSLHESVSSLD 440
>SPAC1556.01c [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC
superfamily
Length = 658
Score = 36.6 bits (83), Expect = 0.13
Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 11/150 (7%)
Query: 450 KEALIQQKTASLQNDIMSFK-NQYERDQVMLEQYDKRVQKLESEL-ESVKEFKEKYQSLA 507
++ +I + Q+DI++ N + + ++ + ++KL S E VKE +E Y+SL
Sbjct: 264 EQQMITIRHLESQSDIINTTINDLKSQMTITDESSEDLEKLHSNFAEKVKEEQELYKSLE 323
Query: 508 KLYSQLRQEHLNILKKMKKTQDDLAEAESEVK-----KLKSSALSNVGIRNNNKGESERE 562
K S L + + ++K DL + + E++ K+K S + N + N E E
Sbjct: 324 KKRSDLESLLKSRRELLEKLTGDLGKIQGEIESLEKLKVKKSTMINEIVHRYNINEINEE 383
Query: 563 ----EAKDRSGMILKSLVESSIKSLQDPIA 588
E + ++ K+ SS K + +A
Sbjct: 384 GIMTEVSKYASLVNKNYEISSGKLKERQVA 413
>Hs7705348 [Z] KOG0247 Kinesin-like protein
Length = 1780
Score = 36.6 bits (83), Expect = 0.13
Identities = 49/194 (25%), Positives = 85/194 (43%), Gaps = 33/194 (17%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSL-AK 508
KE +I+ +L+ + Q E+DQV LE + V++L +ELE ++KEK L K
Sbjct: 1330 KEKIIEDMRMTLEEQEQT---QVEQDQV-LEAKLEEVERLATELE---KWKEKCNDLETK 1382
Query: 509 LYSQLRQEHLN---ILKKMKKTQDDLAEAESEVK-------KLKSSALSNVGIRNNNKGE 558
+ +EH N +L K+ QD+L E+E + + K ++ N + +
Sbjct: 1383 NNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNK 1442
Query: 559 SEREEAKDRSGM--------ILKSLVESSIKSLQ-------DPIASLDVSDLATDLSNAF 603
++ A+DR IL + + LQ +A+L++ A SN
Sbjct: 1443 EMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQ 1502
Query: 604 IDGDINTIVNILPE 617
D +I + I+ E
Sbjct: 1503 KDNEIEQLKRIISE 1516
>Hs4758200 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein) and related
proteins
Length = 2871
Score = 36.6 bits (83), Expect = 0.13
Identities = 34/141 (24%), Positives = 63/141 (44%), Gaps = 19/141 (13%)
Query: 455 QQKTASLQNDIMSFKNQ-----YERDQVM-----LEQYDKRVQKLESELESVKEFKEKYQ 504
Q++ N I KNQ ER+ ++ LEQ R+Q+LE EL K E
Sbjct: 1788 QKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLE--- 1844
Query: 505 SLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEA 564
+ ++ +L E I + + + + E ++K++S + +N+ + E ER +A
Sbjct: 1845 AETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQA 1904
Query: 565 KDRSGMILKSLVESSIKSLQD 585
+ +K + E + L+D
Sbjct: 1905 E------IKRIEERCRRKLED 1919
Score = 33.9 bits (76), Expect = 0.84
Identities = 22/100 (22%), Positives = 47/100 (47%), Gaps = 13/100 (13%)
Query: 448 MEKEALIQQKTA----SLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKY 503
+E E ++Q+ +QND+ +K QY R + + + + +K E E S++ E+
Sbjct: 1843 LEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERL 1902
Query: 504 QSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKS 543
Q+ K + + +K +D E +S+++ +S
Sbjct: 1903 QAEIKRIEE---------RCRRKLEDSTRETQSQLETERS 1933
Score = 32.7 bits (73), Expect = 1.9
Identities = 53/246 (21%), Positives = 103/246 (41%), Gaps = 51/246 (20%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRV--------------QKLESEL 493
++ E + Q++T Q DI F+N + Q+ ++ ++ + +KLE EL
Sbjct: 1540 IDYERVSQERTVKDQ-DITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEEL 1598
Query: 494 ESVKE-FKEKYQSLAKLYSQLRQEHL-----------------NILKKMKKTQDDLAEAE 535
E ++ KE+ + L QL Q + L++ ++TQ++L
Sbjct: 1599 EGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLS 1658
Query: 536 SEVKKLK------SSALSNVGIRNNN--KGESEREEAKDRSGM---ILKSLVESSIKS-- 582
SEV+ L+ ++ +RN + K ++ + + S + L+SL E+ K
Sbjct: 1659 SEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHL 1718
Query: 583 -LQDPIAS--LDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCPQEMQTIAEDFLRC 639
L++ + + L+ DL S A D D N + L + + E+Q + D R
Sbjct: 1719 MLEEELRNLRLEYDDLRRGRSEA--DSDKNATILELRSQLQISNNRTLELQGLINDLQRE 1776
Query: 640 LSSAKQ 645
+ +Q
Sbjct: 1777 RENLRQ 1782
>At1g79280 [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 2111
Score = 36.6 bits (83), Expect = 0.13
Identities = 50/200 (25%), Positives = 91/200 (45%), Gaps = 18/200 (9%)
Query: 477 VMLEQYDKRVQKLESELESVKEFKEKYQSLAKL----YSQLRQEHLNILKKMKKTQDDLA 532
+ L + ++KL E+ES K +Y+S+A++ Q+ H N + +K Q L
Sbjct: 965 IELRTAKEEIEKLRGEVESSKSHMLQYKSIAQVNETALKQMESAHENFRLEAEKRQRSL- 1023
Query: 533 EAESEVKKLKSSALSNVGIRNNNK---GESEREEAKDRSGMILKSLVESS-IKSLQDPIA 588
EAE + + S L N I+ + + + +E+A + + SL E + +K Q
Sbjct: 1024 EAELVSLRERVSELENDCIQKSEQLATAAAGKEDALLSASAEIASLREENLVKKSQIEAM 1083
Query: 589 SLDVSDLATDLSN-----AFIDGDINTIVNILPEFVSLLLRCPQEMQTIAEDF--LRCLS 641
++ +S L DL + V +L E + L + Q + + E+ LR L+
Sbjct: 1084 NIQMSTLKNDLETEHEKWRVAQRNYERQVILLSETIQELTKTSQALAALQEEASELRKLA 1143
Query: 642 SAKQTD-SVINANIAFQEKL 660
A+ + S +NA + +EKL
Sbjct: 1144 DARGIENSELNAKWS-EEKL 1162
Score = 36.2 bits (82), Expect = 0.17
Identities = 41/181 (22%), Positives = 85/181 (46%), Gaps = 22/181 (12%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLA 507
ME L Q+K +++S + D+V +RV +L++ L++V+ +E +
Sbjct: 782 MEVSVLKQEK------ELLSNAEKRASDEV--SALSQRVYRLQATLDTVQSTEEVREETR 833
Query: 508 KLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNN--NKGESEREEAK 565
+ ++EH+ K+ Q + AEA+ E+++ +S+A RN N + EE
Sbjct: 834 AAERRKQEEHI------KQLQREWAEAKKELQEERSNARDFTSDRNQTLNNAVMQVEEMG 887
Query: 566 DRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNA---FIDGDINTIVNILPEFVSLL 622
LK++ S+ + +A +SDL + ++ +D D IV++ + +L+
Sbjct: 888 KELANALKAV---SVAESRASVAEARLSDLEKKIRSSDPKTLDMDSGGIVSLSDKEAALV 944
Query: 623 L 623
+
Sbjct: 945 I 945
Score = 31.2 bits (69), Expect = 5.4
Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 24/131 (18%)
Query: 456 QKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELE------------------SVK 497
+K + + K +YE+++ ++ K+ Q L +LE SVK
Sbjct: 1455 EKNKKIHYTLNMTKRKYEKEK---DELSKQNQSLAKQLEEAKEEAGKRTTTDAVVEQSVK 1511
Query: 498 EFKEK---YQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNN 554
E +EK Q L K QL+ E + +KK ++L + SE K ++ ++
Sbjct: 1512 EREEKEKRIQILDKYVHQLKDEVRKKTEDLKKKDEELTKERSERKSVEKEVGDSLTKIKK 1571
Query: 555 NKGESEREEAK 565
K + + E AK
Sbjct: 1572 EKTKVDEELAK 1582
>7302958 [Z] KOG0240 Kinesin (SMY1 subfamily)
Length = 975
Score = 36.6 bits (83), Expect = 0.13
Identities = 23/118 (19%), Positives = 55/118 (46%), Gaps = 4/118 (3%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
++ AL + N+ + ER + +Q D + +++ + + ++ KE+ +
Sbjct: 418 QRTALANMSASVAVNEQARLATECER---LYQQLDDKDEEINQQSQYAEQLKEQVMEQEE 474
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKD 566
L + R+E+ + +M + Q + A+ EVK++ AL + + + K + + KD
Sbjct: 475 LIANARREYETLQSEMARIQQENESAKEEVKEV-LQALEELAVNYDQKSQEIDNKNKD 531
Score = 30.8 bits (68), Expect = 7.1
Identities = 46/217 (21%), Positives = 91/217 (41%), Gaps = 27/217 (12%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
++++ + I + + +YE Q + + Q+ ES E VKE + + LA Y Q
Sbjct: 465 LKEQVMEQEELIANARREYETLQSEMARIQ---QENESAKEEVKEVLQALEELAVNYDQK 521
Query: 514 RQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILK 573
QE N K + ++L + +S N +E ++ KD S K
Sbjct: 522 SQEIDNKNKDIDALNEELQQKQSVF----------------NAASTELQQLKDMSSHQKK 565
Query: 574 SLVE---SSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCPQEMQ 630
+ E + ++ L + ++ + + DL + + G T + + E ++ +M+
Sbjct: 566 RITEMLTNLLRDLGEVGQAIAPGESSIDLKMSALAG---TDASKVEEDFTMARLFISKMK 622
Query: 631 TIAEDFLRCLSSAKQTDSVINANIAFQEKLKRLGEIR 667
T A++ + S+ + + N I+ E K LGE R
Sbjct: 623 TEAKNIAQRCSNMETQQADSNKKISEYE--KDLGEYR 657
>7301097 [D] KOG0018 Structural maintenance of chromosome protein 1 (sister
chromatid cohesion complex Cohesin subunit SMC1)
Length = 1238
Score = 36.6 bits (83), Expect = 0.13
Identities = 34/145 (23%), Positives = 69/145 (47%), Gaps = 21/145 (14%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLE-------QYDKRVQKLESELESVKEFKEK 502
K++ Q + A++++ I +N+ + V LE QYD ++Q+++S+L+ EF K
Sbjct: 716 KKSRKQSELATVESQIKGLENRLKYSMVDLESSKKSISQYDNQLQQVQSQLD---EFGPK 772
Query: 503 YQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESERE 562
+ + Q R+EH+ +K+ +D K+ +S +G++N + E ERE
Sbjct: 773 ILEIER-RMQNREEHIQEIKENMNNVED---------KVYASFCRRLGVKNIRQYE-ERE 821
Query: 563 EAKDRSGMILKSLVESSIKSLQDPI 587
+ ++ E I S+ +
Sbjct: 822 LVMQQERARKRAEFEQQIDSINSQL 846
Score = 33.9 bits (76), Expect = 0.84
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 497 KEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSS-ALSNVGIRNNN 555
K + EK+ + K+ + QE L L K + Q +LA ES++K L++ S V + ++
Sbjct: 690 KRWDEKHMAQLKMQKERLQEELKELVKKSRKQSELATVESQIKGLENRLKYSMVDLESSK 749
Query: 556 KGESE 560
K S+
Sbjct: 750 KSISQ 754
>YLL026w [O] KOG1051 Chaperone HSP104 and related ATP-dependent Clp
proteases
Length = 908
Score = 36.2 bits (82), Expect = 0.17
Identities = 33/132 (25%), Positives = 64/132 (48%), Gaps = 10/132 (7%)
Query: 453 LIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQ 512
L +QK ASLQ ++ + +Y ++ E+ + +KL+ + + +Y + +
Sbjct: 447 LARQKEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATA--AD 504
Query: 513 LRQEHL-NILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMI 571
LR + +I K+++K +D +AE E A +N I+N ++ E A +G+
Sbjct: 505 LRYFAIPDIKKQIEKLEDQVAEEERR-------AGANSMIQNVVDSDTISETAARLTGIP 557
Query: 572 LKSLVESSIKSL 583
+K L ES + L
Sbjct: 558 VKKLSESENEKL 569
>SPCC162.06c [U] KOG1655 Protein involved in vacuolar protein sorting
Length = 210
Score = 36.2 bits (82), Expect = 0.17
Identities = 34/173 (19%), Positives = 76/173 (43%), Gaps = 12/173 (6%)
Query: 456 QKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQ 515
Q TASL + I S + + +V + + D ++ + ++ + + + + L+Q
Sbjct: 12 QPTASLTDAIDSLDKRSDSVEVKIAKLDAQLSVFQQKIANTRPGPGQ--------TALKQ 63
Query: 516 EHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSL 575
+N+L++ K + L + + + ++ +A++ ++N +E + K++
Sbjct: 64 RAMNVLRQKKIYESQLQQLQQQSFNMEQAAMTTESLKNTMATVQTMQETARQLKSQSKNV 123
Query: 576 VESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCPQE 628
I+ LQD I D D A +L+ G T +N+ E + L Q+
Sbjct: 124 SIEKIEKLQDEIQ--DYMDAAGELNEVL--GQNMTDINVDEEELDAELEALQQ 172
>Hs4759058 [T] KOG2008 BTK-associated SH3-domain binding protein SAB
Length = 425
Score = 36.2 bits (82), Expect = 0.17
Identities = 36/130 (27%), Positives = 59/130 (44%), Gaps = 11/130 (8%)
Query: 485 RVQKLESELE-SVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKS 543
R+++LE +L+ ++ + K ++ AK Y QL Q +KKT DDL + K
Sbjct: 163 RMRQLEKKLKRAINKSKPYFELKAKYYVQLEQ--------LKKTVDDLQAKLTLAKGEYK 214
Query: 544 SALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAF 603
AL N+ + ++ E R A G + + E S S++D S D + S AF
Sbjct: 215 MALKNLEMISDEIHERRRSSAMGPRGCGVGA--EGSSTSVEDLPGSKPEPDAISVASEAF 272
Query: 604 IDGDINTIVN 613
D + V+
Sbjct: 273 EDDSCSNFVS 282
>Hs20373153 [Z] KOG0161 Myosin class II heavy chain
Length = 2567
Score = 36.2 bits (82), Expect = 0.17
Identities = 32/147 (21%), Positives = 69/147 (46%), Gaps = 16/147 (10%)
Query: 457 KTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQ---- 512
KT+ + ++ +Q E+ + E+ K + L ++LES+ E L +
Sbjct: 1825 KTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYR 1884
Query: 513 LRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVG------------IRNNNKGESE 560
L+ E ++LK++ + QDDL E + K L + + +++G + +K + +
Sbjct: 1885 LQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQ 1944
Query: 561 REEAKDRSGMILKSLVESSIKSLQDPI 587
+ A+ R + +S V+ +I S Q+ +
Sbjct: 1945 LQVAQMRIEYLEQSTVDRAIVSRQEAV 1971
Score = 31.6 bits (70), Expect = 4.2
Identities = 28/111 (25%), Positives = 54/111 (48%), Gaps = 8/111 (7%)
Query: 484 KRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKT-QDDLAEAESEVKKLK 542
+R+ KLES ++ + + ++ K QLRQ +++MK+ Q D + E E++ ++
Sbjct: 1688 ERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVR 1747
Query: 543 SSALSNVGIRNNNKGESEREEAKDRSGMIL--KSLVESSIKSLQDPIASLD 591
S + ++ E + E+ + M+L K +E I +L D I D
Sbjct: 1748 QSCQKRL-----HQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRD 1793
>Hs12667788 [Z] KOG0161 Myosin class II heavy chain
Length = 1960
Score = 36.2 bits (82), Expect = 0.17
Identities = 39/210 (18%), Positives = 90/210 (42%), Gaps = 11/210 (5%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEK----YQSLAKL 509
++++ A+L + K + E LE ++ +KL+ +LE + + E+ Y L K
Sbjct: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
Query: 510 YSQLRQEHLNILKKMKKTQDDLAEAESEVKKL-----KSSALSNVGIRNNNKGESEREEA 564
++L+QE ++L + + E + KK + +S ++ E+E E
Sbjct: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1474
Query: 565 KDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLR 624
+ ++ + ++L E+ + + + DL ++ D+ V+ L + L +
Sbjct: 1475 ETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSS--KDDVGKSVHELEKSKRALEQ 1532
Query: 625 CPQEMQTIAEDFLRCLSSAKQTDSVINANI 654
+EM+T E+ L + + + N+
Sbjct: 1533 QVEEMKTQLEELEDELQATEDAKLRLEVNL 1562
Score = 34.7 bits (78), Expect = 0.49
Identities = 37/219 (16%), Positives = 93/219 (41%), Gaps = 12/219 (5%)
Query: 456 QKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELES-VKEFKEKYQSLAKLYSQLR 514
++ +L+ ++ + Q + + ++ V L+ LE K + + Q + + +SQ
Sbjct: 1139 EELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAV 1198
Query: 515 QEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKS 574
+E L++ K+ + +L +A+ ++ + + V + KG+SE + K +
Sbjct: 1199 EELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKK-----VEAQ 1253
Query: 575 LVESSIKSLQDPIASLDVSDLATDLS------NAFIDGDINTIVNILPEFVSLLLRCPQE 628
L E +K + +++D T L + + + +F +L +
Sbjct: 1254 LQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDT 1313
Query: 629 MQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKRLGEIR 667
+ + E+ + LS + + V + +F+E+L+ E +
Sbjct: 1314 QELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAK 1352
Score = 33.5 bits (75), Expect = 1.1
Identities = 31/146 (21%), Positives = 65/146 (44%), Gaps = 21/146 (14%)
Query: 457 KTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQ-----------S 505
K++ L D + ++Q + Q +L++ +++ L ++L+ V++ K ++ +
Sbjct: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
Query: 506 LAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAK 565
L K + L + ++ KKM+ + L AE +KL+ +G S+R E K
Sbjct: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDL----------EGLSQRHEEK 1404
Query: 566 DRSGMILKSLVESSIKSLQDPIASLD 591
+ L+ + L D + LD
Sbjct: 1405 VAAYDKLEKTKTRLQQELDDLLVDLD 1430
Score = 33.1 bits (74), Expect = 1.4
Identities = 29/117 (24%), Positives = 61/117 (51%), Gaps = 8/117 (6%)
Query: 456 QKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVK-EFKEKYQSLA---KLYS 511
+K L++ I + E ++ + +K+ + L ELE++K E ++ S A +L S
Sbjct: 1104 KKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRS 1163
Query: 512 QLRQEHLNILKKMKKTQDDLAEAE-SEVKKLKSSALSNVG--IRNNNKGESEREEAK 565
+ R++ +NILKK + + EA+ E+++ S A+ + + + ++ E+AK
Sbjct: 1164 K-REQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK 1219
Score = 30.4 bits (67), Expect = 9.3
Identities = 39/172 (22%), Positives = 79/172 (45%), Gaps = 31/172 (18%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELE--------SVKEF 499
+E+E +QK + + + E +Q++LE + ++ K + LE ++ E
Sbjct: 952 LEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE 1011
Query: 500 KEKYQSLAKLYS-----------QLRQE---HLNILKKMKKTQDDLAEAESEVKKLKSSA 545
+EK +SLAKL + +LR+E + K +K + D + ++ +L++
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ- 1070
Query: 546 LSNVGIRNNNKGE------SEREEAKDRSGMILKSL--VESSIKSLQDPIAS 589
++ + ++ K E + EE + M LK + +ES I LQ+ + S
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLES 1122
>CE18406 [O] KOG4185 Predicted E3 ubiquitin ligase
Length = 244
Score = 36.2 bits (82), Expect = 0.17
Identities = 29/103 (28%), Positives = 57/103 (55%), Gaps = 10/103 (9%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVK-EFKEKYQSLAK 508
K+AL+ Q+ + + +N+Y D LE+ ++R++ L+ +L+ ++ + + +SL +
Sbjct: 69 KQALMNQQMITQH---LKKRNEYLDD---LEEANERIKILDEKLDKLEAKISKTEESLVQ 122
Query: 509 LYSQL--RQEHLNILKKMKKTQDDLAEA-ESEVKKLKSSALSN 548
S L + E L ++K K DD A + E+ +LK+S L N
Sbjct: 123 SVSMLLEKDEQLKTIRKEMKIMDDERSAFDQELTRLKTSRLEN 165
>7292646 [R] KOG4436 Predicted GTPase activator NB4S/EVI5 (contains TBC
domain)/Calmodulin-binding protein Pollux (contains PTB
and TBC domains)
Length = 803
Score = 36.2 bits (82), Expect = 0.17
Identities = 35/166 (21%), Positives = 74/166 (44%), Gaps = 11/166 (6%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEF----KEKYQSLAKL 509
++ K L+ + NQ R E++ K ++LE + K+ +E+ + L
Sbjct: 632 LRLKVMELETQVQVSTNQLRRQD---EEHKKLKEELEMAVTREKDMSNKAREQQHRYSDL 688
Query: 510 YSQLRQEHLNILKKMKKTQDDLAEAESEVKKLK---SSALSNVGIRNNNKGESEREEAKD 566
S+++ E +N+ K + +AE + E+ +L+ S L+ +R N + + +D
Sbjct: 689 ESRMKDELMNVKIKFTEQSQTVAELKQEISRLETKNSEMLAEGELRANLDDSDKVRDLQD 748
Query: 567 RSGMILKSLVESSIKSL-QDPIASLDVSDLATDLSNAFIDGDINTI 611
R + + +++KS + P A L S + + S D+N +
Sbjct: 749 RLADMKAEVSLTALKSRGKFPGAKLRSSSIQSIESTEIDFNDLNMV 794
>YBL063w [Z] KOG0243 Kinesin-like protein
Length = 1111
Score = 35.8 bits (81), Expect = 0.22
Identities = 21/103 (20%), Positives = 51/103 (49%), Gaps = 15/103 (14%)
Query: 456 QKTASLQNDIMSFKNQ------------YERDQVMLEQYDKRVQKLESELESVKEFKEKY 503
Q+ L+ND+ + +N+ YE + +++++ + ++ L E +K+FKE Y
Sbjct: 431 QEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLR---EQIKKFKENY 487
Query: 504 QSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSAL 546
+ + + L+ E ++ ++ D + SE++K+ + L
Sbjct: 488 LNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNL 530
>SPBC19F8.03c [TU] KOG0251 Clathrin assembly protein AP180 and related proteins
contain ENTH domain
Length = 649
Score = 35.8 bits (81), Expect = 0.22
Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 5/107 (4%)
Query: 15 TLEKSIKKALSGGDVAPKRKHVRACIVYTWDHKSSKTFFNLLKLQPYATDELQ---LFKA 71
T E+++KKA APK KHV + T + +T N+++ E +FK
Sbjct: 9 TYERAVKKATKVKLAAPKYKHVEIILEATTE--DPETLENVIQALCERLKEQSWTIVFKT 66
Query: 72 LVLLHKVLQEGHPSALVEGIRNIDWIESLSRIFSVDSDDGSKYGSSR 118
L++ H +L+EG P+ + + I + + S+ + + Y SR
Sbjct: 67 LIVFHVMLKEGAPNTTIVALSQRPRILEVLKASSLLAQGKNIYNYSR 113
>Hs6005904 [K] KOG4673 Transcription factor TMF TATA element modulatory factor
Length = 1093
Score = 35.8 bits (81), Expect = 0.22
Identities = 30/148 (20%), Positives = 72/148 (48%), Gaps = 11/148 (7%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEF-------- 499
ME+ + ++ N I + + + ++ M+ + +K+V++LE EL+ +K+
Sbjct: 559 MEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVE 618
Query: 500 KEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVG--IRNNNKG 557
K+ +++ KL S + ++ + L +++ D+L E ++ SA + + N
Sbjct: 619 KQHRENIKKLNSMVERQEKD-LGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAK 677
Query: 558 ESEREEAKDRSGMILKSLVESSIKSLQD 585
+SE +EA M K + ++++ Q+
Sbjct: 678 DSEAQEAALSREMKAKEELSAALEKAQE 705
>Hs4507659 [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 2349
Score = 35.8 bits (81), Expect = 0.22
Identities = 49/240 (20%), Positives = 104/240 (42%), Gaps = 44/240 (18%)
Query: 469 KNQYERDQVMLEQYDKRVQKLESELESVKEF----KEKYQSLAKLYSQ-----LRQEHLN 519
+ ++E QV +Y +RV+ LE EL+ +++ +EK Q AK +Q + E +N
Sbjct: 1211 ETRFEVAQVESLRYRQRVELLERELQELEDSLNAEREKVQVTAKTMAQHEELMKKTETMN 1270
Query: 520 IL--------KKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMI 571
++ ++ ++ + DL + +++V+KL+ L + E ++SGM+
Sbjct: 1271 VVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPL---------QEANAELSEKSGML 1321
Query: 572 L--KSLVESSI---KSLQDPIASLDVSDLATDLSNAFIDGDINT--IVNILPEFVSL--- 621
K L+E + K+ + S + + +++T I + E L
Sbjct: 1322 QAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAE 1381
Query: 622 -------LLRCPQEMQTIAEDFLRCLSSAKQTDSVINANIA-FQEKLKRLGEIRQYSYRY 673
L +Q++ ED + + + ++A I QEK+K + ++++ RY
Sbjct: 1382 IARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRY 1441
Score = 35.8 bits (81), Expect = 0.22
Identities = 43/214 (20%), Positives = 100/214 (46%), Gaps = 24/214 (11%)
Query: 474 RDQVMLEQYDKR---------VQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKM 524
+DQ++LE+ + + V+++E++ +K +E+Y+ K + L + +K++
Sbjct: 406 QDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEI 465
Query: 525 KKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSL- 583
++ Q+D +A + S+V R+N + E + ++ + ++L L E+ +
Sbjct: 466 QRLQEDTDKANKQ---------SSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVI 516
Query: 584 -QDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCPQEMQTIAEDFLRCLSS 642
+ ++S D+S + +S + + L + LL +E+ E + +S
Sbjct: 517 RDEEVSSADISSSSEVISQHLVS---YRNIEELQQQNQRLLVALRELGETREREEQETTS 573
Query: 643 AKQTDSVINANIAFQEKLKRLGEIRQYSYRYGDS 676
+K T+ + A E L++L + RQ+ + DS
Sbjct: 574 SKITELQLKLESALTE-LEQLRKSRQHQMQLVDS 606
>Hs15313972 [Z] KOG0161 Myosin class II heavy chain
Length = 1647
Score = 35.8 bits (81), Expect = 0.22
Identities = 37/159 (23%), Positives = 74/159 (46%), Gaps = 24/159 (15%)
Query: 455 QQKTASLQNDIMS-FKNQYERDQVMLEQYDK---RVQKLESELESVKEFKEKYQSLAKLY 510
+Q+ + +D+ S + + ER+Q++ + K +Q LE +L+ + ++K Q L K+
Sbjct: 588 KQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ-LEKVT 646
Query: 511 SQ------------LRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNK-- 556
++ L ++ +K+ K +D +AE S++ + + A + IRN +
Sbjct: 647 AEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVM 706
Query: 557 ----GESEREEAKDRSGM-ILKSLVESSIKSLQDPIASL 590
E ++E K R + K ++ LQD IA L
Sbjct: 707 ISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAEL 745
Score = 34.3 bits (77), Expect = 0.64
Identities = 31/136 (22%), Positives = 63/136 (45%), Gaps = 6/136 (4%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKL 509
K AL+ +K L+ I + + E +Q +E + R +K +++++ +S A+
Sbjct: 1395 KSALLDEKRR-LEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQK 1453
Query: 510 YSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSG 569
RQ+ + ++ K+ + L E E VK + +S + + E +EAK+R+
Sbjct: 1454 SDNARQQ---LERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAA 1510
Query: 570 MILKSLVESSIKSLQD 585
LV + K L++
Sbjct: 1511 --ANKLVRRTEKKLKE 1524
>Hs13124877 [Z] KOG0161 Myosin class II heavy chain
Length = 1266
Score = 35.8 bits (81), Expect = 0.22
Identities = 33/156 (21%), Positives = 69/156 (44%), Gaps = 34/156 (21%)
Query: 479 LEQYDKRVQKLESELESVKE-----------FKEKYQSLAKLYSQLRQEHLNILKKMKKT 527
L++ +R QK E+EL+ +++ +E+ Q+ +LY++ + + + K ++
Sbjct: 861 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL 920
Query: 528 QDDLAEAESEVKKLKSSALSNVGIRNNN-------KGESEREEAKDRSGMILKSLVESSI 580
++ L E E+ +++ + R + + E EEA + + K E+ I
Sbjct: 921 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI 980
Query: 581 KSLQDPIASLD----------------VSDLATDLS 600
K L+D I +D +SDL T+L+
Sbjct: 981 KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016
>CE09349 [Z] KOG0161 Myosin class II heavy chain
Length = 1963
Score = 35.8 bits (81), Expect = 0.22
Identities = 31/155 (20%), Positives = 68/155 (43%), Gaps = 7/155 (4%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVK-EFKEKYQSLAKLYSQL 513
QQK AS Q + +Q ++ + +K+E+E+E++K + ++ SL K S+
Sbjct: 920 QQKDASKQ--LSELNDQLADNEDRTADVQRAKKKIEAEVEALKKQIQDLEMSLRKAESEK 977
Query: 514 RQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILK 573
+ + I + QD++ + + + KL I + + EE K +K
Sbjct: 978 QSKDHQI----RSLQDEMQQQDEAIAKLNKEKKHQEEINRKLMEDLQSEEDKGNHQNKVK 1033
Query: 574 SLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDI 608
+ +E ++ L+D + + D ++G++
Sbjct: 1034 AKLEQTLDDLEDSLEREKRARADLDKQKRKVEGEL 1068
Score = 30.8 bits (68), Expect = 7.1
Identities = 21/96 (21%), Positives = 48/96 (49%), Gaps = 10/96 (10%)
Query: 456 QKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQ 515
++ LQ + K +ER Q ++ DK QKL+++ + V+E +E + Y QL
Sbjct: 1854 RRVRELQFQVDEDKKNFERLQDLI---DKLQQKLKTQKKQVEEAEELANLNLQKYKQLTH 1910
Query: 516 EHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGI 551
+ ++ ++ +AE+ + K++S + ++ +
Sbjct: 1911 Q-------LEDAEERADQAENSLSKMRSKSRASASV 1939
>At5g62410 [BD] KOG0933 Structural maintenance of chromosome protein 2
(chromosome condensation complex Condensin subunit E)
Length = 1175
Score = 35.8 bits (81), Expect = 0.22
Identities = 31/121 (25%), Positives = 63/121 (51%), Gaps = 21/121 (17%)
Query: 479 LEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL---------------RQEHLNILKK 523
L+ + KR+ +ES+++ ++ + K+ + Y+QL + EH + +
Sbjct: 686 LQGHQKRLADVESQIKELQPLQMKFTDV---YAQLELKTYDLSLFLKRAEQNEHHKLGEA 742
Query: 524 MKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSL 583
+KK +++L EA+S++K+ K A N + S ++ K+R G LK L E +IK++
Sbjct: 743 VKKLEEELEEAKSQIKE-KELAYKNCFDAVSKLENSIKDHDKNREGR-LKDL-EKNIKTI 799
Query: 584 Q 584
+
Sbjct: 800 K 800
>At4g24270 [A] KOG0128 RNA-binding protein SART3 (RRM superfamily)
Length = 768
Score = 35.8 bits (81), Expect = 0.22
Identities = 25/107 (23%), Positives = 51/107 (47%), Gaps = 11/107 (10%)
Query: 471 QYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDD 530
++ER+ LE +D VQK+ LE ++ + + +S S +EH + +K ++ ++
Sbjct: 484 RFEREHGDLEHFDLAVQKVMPRLEELQLMRLQQESTPVKPSAGLKEHSSQKRKAEQNVEE 543
Query: 531 LAEAESEVKKLKSS-----------ALSNVGIRNNNKGESEREEAKD 566
+ A+ + +K + A NV N +S++EE +D
Sbjct: 544 ESLAKRQKRKSQKEVDLGGQSATVPATKNVKAENGKTADSDKEETED 590
>YKL014c [S] KOG1791 Uncharacterized conserved protein
Length = 1764
Score = 35.4 bits (80), Expect = 0.29
Identities = 43/182 (23%), Positives = 84/182 (45%), Gaps = 28/182 (15%)
Query: 449 EKEALIQQKTASLQNDI--MSFKNQYERDQVMLEQYDKRVQKLESELESVKEF---KEKY 503
++ AL+ +K+ + N I + F+ ++ L ++ + +QK+ E+V+E+ E Y
Sbjct: 857 KRNALLMKKSRFMCNLIGAVCFETGHQ-----LVEFREIIQKVVFSGENVEEYANYNELY 911
Query: 504 QS------LAKLYSQLRQEHLNIL----KKMKKTQDDLAEAESEVKKLKSSALSNVGIRN 553
Q L + L L L K++ T++ L + +E K +K S + N+
Sbjct: 912 QKEDVNAFLTSVSEYLSTSALTSLLMCSTKLESTRNILQKLFNEGKTIKISLVKNI---- 967
Query: 554 NNKGESEREEAKDRSGMILKSLVESS---IKSLQDPIASLDVSDLATDLSNAFIDGDINT 610
NK +E + + L E + + + DP+ L +S+ T L N+F+ D+N
Sbjct: 968 LNKAANEDPASIKEVNISLAKFFEENKVCVDASSDPMGKLSLSE-TTSLINSFVSSDLNY 1026
Query: 611 IV 612
+V
Sbjct: 1027 LV 1028
>Hs11342672 [Z] KOG0161 Myosin class II heavy chain
Length = 1940
Score = 35.4 bits (80), Expect = 0.29
Identities = 41/169 (24%), Positives = 79/169 (46%), Gaps = 15/169 (8%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESEL----ESVKEFKEKYQ 504
E EA +++ + SL ++ KN YE LE + + LE E+ E + E +
Sbjct: 1467 ELEASLKE-SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIH 1525
Query: 505 SLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEA 564
L K Q+ E +I +++ + L E+++ +++ L+ V K E +R+ A
Sbjct: 1526 ELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLE-LTQV------KSEIDRKIA 1578
Query: 565 -KDRSGMILKSLVESSIKSLQDPI-ASLDVSDLATDLSNAFIDGDINTI 611
KD LK + +++++Q + A + + A L ++GD+N I
Sbjct: 1579 EKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKK-MEGDLNEI 1626
Score = 32.7 bits (73), Expect = 1.9
Identities = 29/136 (21%), Positives = 58/136 (42%), Gaps = 5/136 (3%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
+++ L + + Q E +K Q+L+ E+E + E+ SLA +
Sbjct: 1387 LEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKK 1446
Query: 514 RQEHLNILKKMK-KTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMIL 572
++ +L + K K ++ AE E+ +K+ +S + ++N + ++ E R L
Sbjct: 1447 QRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNL 1506
Query: 573 KSLVESSIKSLQDPIA 588
E I L + IA
Sbjct: 1507 ----EQEIADLTEQIA 1518
Score = 31.6 bits (70), Expect = 4.2
Identities = 29/132 (21%), Positives = 71/132 (52%), Gaps = 20/132 (15%)
Query: 474 RDQVMLEQYDKRVQKLESEL---ESVKEFKE-KYQSLAKLYSQLR---------QEHLNI 520
R +M ++ K VQ+ ES +++ F K+ KL+ +++ +E +
Sbjct: 794 RGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATM 853
Query: 521 LKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESERE-----EAKDRSGMILKS- 574
++ +KT+D+LA++E++ K+L+ ++ V +N+ + + + E +A++R ++K+
Sbjct: 854 KEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAK 913
Query: 575 -LVESSIKSLQD 585
+E+ IK + +
Sbjct: 914 FQLEAKIKEVTE 925
>CE25302 [D] KOG0964 Structural maintenance of chromosome protein 3 (sister
chromatid cohesion complex Cohesin subunit SMC3)
Length = 1269
Score = 35.4 bits (80), Expect = 0.29
Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 25/132 (18%)
Query: 469 KNQYERDQVMLEQYDKRVQKLESELESVKEF-------------------KEKYQSLAKL 509
K + E+ Q +L+ D+R+Q LE+E E +KE+ KE + KL
Sbjct: 184 KMKTEKIQGLLKYIDERLQTLENEKEDLKEYQKLDKTKRSVEYTMYDNTNKEAIKEKTKL 243
Query: 510 YSQ---LRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKD 566
Q L Q+ N+ ++ ++A+ +++ KKL+S G+R + + E
Sbjct: 244 DEQKVELNQKDNNVKSQLNDVIAEMAKLKTDKKKLESLGR---GLREDKETLQAEETKMV 300
Query: 567 RSGMILKSLVES 578
M LK ++S
Sbjct: 301 EEKMTLKLEIDS 312
>CE04618 [Z] KOG0161 Myosin class II heavy chain
Length = 1956
Score = 35.4 bits (80), Expect = 0.29
Identities = 32/160 (20%), Positives = 69/160 (43%), Gaps = 22/160 (13%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQ-------VMLEQYDKRVQKLESELESVKEFKEK 502
K+ ++K L I +N+ E ++ ++ + ++ +LE +LE KE+
Sbjct: 1573 KDVEAEEKRRGLLKQIRDLENELENEKRGKSGAVSHRKKIENQIGELEQQLEVANRLKEE 1632
Query: 503 YQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEV-KKLKSSALSNVGIRNNNKG---- 557
Y K Q+ +E+ ++ ++ ++D+A E +K ++ +R N+G
Sbjct: 1633 YNKQLKKNQQIIKEYQIECEEARQAKEDIAALLREADRKFRAVEAEREQLREANEGLMQA 1692
Query: 558 -------ESEREEAKDRSGMIL---KSLVESSIKSLQDPI 587
E EE + + G I K +E+ I L++ +
Sbjct: 1693 RKQLELENDELEELRAKGGGISSEEKRRLEAKIAQLEEEL 1732
Score = 32.7 bits (73), Expect = 1.9
Identities = 28/140 (20%), Positives = 66/140 (47%), Gaps = 4/140 (2%)
Query: 461 LQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKE-FKEKYQSLAKLYSQLRQEHLN 519
L+N + + R++ + ++ +KL +ELE K+ EK + +L +QL +
Sbjct: 1024 LENQLHELEQDLNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNNQLMKRDEE 1083
Query: 520 ILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESS 579
+ ++ + ++ A K+++ + +R + E+ER A++++ M + +V
Sbjct: 1084 LQHQLTRYDEESANVTLMQKQMRDMQTTIDELREDM--ETER-NARNKAEMTRREVVAQL 1140
Query: 580 IKSLQDPIASLDVSDLATDL 599
K D + +D + + DL
Sbjct: 1141 EKVKGDVLDKVDEATMLQDL 1160
>At5g48600 [BD] KOG0996 Structural maintenance of chromosome protein 4
(chromosome condensation complex Condensin subunit C)
Length = 1241
Score = 35.4 bits (80), Expect = 0.29
Identities = 27/99 (27%), Positives = 43/99 (43%), Gaps = 11/99 (11%)
Query: 457 KTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKY----QSLAKLYSQ 512
K +Q DI + R V +E K ++KL +E KE+ ++L +
Sbjct: 847 KVEKIQTDIDKNNTEINRCNVQIETNQKLIKKLTKGIEEATREKERLEGEKENLHVTFKD 906
Query: 513 LRQEHLNILKKMKKTQ-------DDLAEAESEVKKLKSS 544
+ Q+ I + KKTQ D L A+S+ + LK S
Sbjct: 907 ITQKAFEIQETYKKTQQLIDEHKDVLTGAKSDYENLKKS 945
Score = 32.0 bits (71), Expect = 3.2
Identities = 23/98 (23%), Positives = 51/98 (51%), Gaps = 15/98 (15%)
Query: 452 ALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKE-----------FK 500
A I ++ SLQN +N + ++V +++ ++ ++K ES E K+ K
Sbjct: 274 AKITEQRDSLQN----LENSLKDERVKMDESNEELKKFESVHEKHKKRQEVLDNELRACK 329
Query: 501 EKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEV 538
EK++ + + R++ ++ +K+KK +D L + S++
Sbjct: 330 EKFKEFERQDVKHREDLKHVKQKIKKLEDKLEKDSSKI 367
>7297163 [R] KOG0249 LAR-interacting protein and related proteins
Length = 1205
Score = 35.4 bits (80), Expect = 0.29
Identities = 26/113 (23%), Positives = 58/113 (51%), Gaps = 16/113 (14%)
Query: 451 EALIQQKTASLQNDIMSFKNQY-----ERDQVM--LEQYDKRVQKLESELESVKEFKEKY 503
E I Q+++ + +F+ ERD++M L + +R+ + E++L V++ ++
Sbjct: 14 EDSISQRSSQFSGEDANFEQLMVSMLDERDKLMDSLREAQERLNETENKLRDVEKERDSL 73
Query: 504 QSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNK 556
Q ++ + L QE + K++ + ++ L E + E+ +LK+ RNN +
Sbjct: 74 QR--QINANLPQEFATLTKELTQARETLLERDEEIGELKAE-------RNNTR 117
Score = 32.0 bits (71), Expect = 3.2
Identities = 33/123 (26%), Positives = 55/123 (43%), Gaps = 14/123 (11%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKY-QSLAKLYSQL 513
Q + A LQ D+ Q E + + +KR + E S+ + EK Q L +QL
Sbjct: 305 QDQCAKLQRDLRENVAQKEDQEERITTLEKRYLNAQRESTSLHDLNEKLEQELRHKEAQL 364
Query: 514 R--QEHLN-ILKKMKKTQDDLAEAE------SEVKKLKSSALSNVGIRNNNKGESEREEA 564
+ +E + I +K++ ++ LA+ E K + AL+ VG NK + A
Sbjct: 365 KLHEEKIGAIEEKLELSEQKLAQHAKLQPDMEEQLKARMEALTKVG----NKAQERHGSA 420
Query: 565 KDR 567
+DR
Sbjct: 421 EDR 423
>7291892 [Z] KOG0161 Myosin class II heavy chain
Length = 2056
Score = 35.4 bits (80), Expect = 0.29
Identities = 40/165 (24%), Positives = 75/165 (45%), Gaps = 20/165 (12%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESEL-ESVKEFKEKYQSLAKLYSQ 512
+Q+K LQ + + NQ E ++ K +ES+L E+ + +E+ + L S+
Sbjct: 1361 LQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSK 1420
Query: 513 LRQ--EHLNILKKMKKTQDD--------LAEAESEVKKLKSSALSNVGIRNNNKGESERE 562
LRQ L++ + D+ LAE ++++++K A + + E E
Sbjct: 1421 LRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQEIKKKAEEDADL------AKELE 1474
Query: 563 EAKDRSGMILKSLVESSIKSLQDPIASLDVS--DLATDLSNAFID 605
E K R +++L E +K L LD S + ++L +A I+
Sbjct: 1475 EGKKRLNKDIEAL-ERQVKELIAQNDRLDKSKKKIQSELEDATIE 1518
Score = 33.9 bits (76), Expect = 0.84
Identities = 32/169 (18%), Positives = 75/169 (43%), Gaps = 3/169 (1%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E + + + L++ + + + E ++ + +KLE ++ ++E E+ ++ +
Sbjct: 991 ESRSRLMARKQELEDMMQELETRIEEEEERVLALGGEKKKLELNIQDLEEQLEEEEAARQ 1050
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
+L+ E + + K+KK ++DLA + + +KL N+ EE K +
Sbjct: 1051 ---KLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTLAEEEEKAKH 1107
Query: 569 GMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPE 617
LK+ E++I L++ + +D S I+ ++ + L E
Sbjct: 1108 LAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNE 1156
Score = 31.2 bits (69), Expect = 5.4
Identities = 30/161 (18%), Positives = 70/161 (42%), Gaps = 14/161 (8%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKE-FKEKYQSLA 507
EK + + A + I + + +DQ ++ D+ +K+E+E+ +KE E+ +
Sbjct: 1103 EKAKHLAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVD 1162
Query: 508 KLYSQLRQEHLNILKKMKKTQDDLA----------EAESEVKKLKSSALSNVGIRNNNKG 557
++ +QL + + + + + ++ A E ES++ +++ + R K
Sbjct: 1163 EMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAAR--AKA 1220
Query: 558 ESEREEAKDRSGMILKSLVES-SIKSLQDPIASLDVSDLAT 597
E R + + + L++S + Q + S +LAT
Sbjct: 1221 EKVRRDLSEELEALKNELLDSLDTTAAQQELRSKREQELAT 1261
>Hs4502781_1 [Z] KOG0242 Kinesin-like protein
Length = 731
Score = 35.4 bits (80), Expect = 0.29
Identities = 46/186 (24%), Positives = 83/186 (43%), Gaps = 30/186 (16%)
Query: 487 QKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAES-EVKKLKSSA 545
+ +ESEL S++ Y +L Y QLR E + K+K+ ++DL E E+ E K K
Sbjct: 494 ENIESELNSLRA---DYDNLVLDYEQLRTEKEEMELKLKE-KNDLDEFEALERKTKKDQE 549
Query: 546 LSNVGIRNNNKGESEREEAKDR-------SGMILKSLVESSIKSLQDPIASLDVSDLATD 598
+ + +N K + E ++ S + L E IK LQ+ I S + ++ D
Sbjct: 550 MQLIHEISNLKNLVKHREVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMD 609
Query: 599 LSNAFIDGDINTIVNILPEFVSLLLRCPQEM-QTIAEDFLRCLSSAKQTDSVINANIAFQ 657
LS + + P++M QT+ + L + +++ + + N+ +
Sbjct: 610 LSYSLES-----------------IEDPKQMKQTLFDAETVALDAKRESAFLRSENLELK 652
Query: 658 EKLKRL 663
EK+K L
Sbjct: 653 EKMKEL 658
Score = 30.4 bits (67), Expect = 9.3
Identities = 30/108 (27%), Positives = 50/108 (45%), Gaps = 14/108 (12%)
Query: 450 KEALIQQKTASLQNDIM-SFKNQYERDQVMLEQYDKRVQKLESELESV------KEFKEK 502
+E + QK +++ D+ S ++ + Q+ +D L+++ ES E KEK
Sbjct: 595 QEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEK 654
Query: 503 YQSLAKLYS------QLRQEHLNILKKMK-KTQDDLAEAESEVKKLKS 543
+ LA Y QL Q L KKM+ + +L A +E+ KL S
Sbjct: 655 MKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTS 702
>YNL250w [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC
superfamily
Length = 1312
Score = 35.0 bits (79), Expect = 0.38
Identities = 44/191 (23%), Positives = 81/191 (42%), Gaps = 38/191 (19%)
Query: 476 QVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAE 535
Q ++QY++ V ++ES+L + E + K+ K+ D +
Sbjct: 230 QTKIDQYNEEVSEIESQLNEITEKSD---------------------KLFKSNQDFQKIL 268
Query: 536 SEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDL 595
S+V+ LK++ LS I + K S + D S L++L+ + K L D + + DL
Sbjct: 269 SKVENLKNTKLS---ISDQVKRLSNSIDILDLSKPDLQNLLANFSKVLMD--KNNQLRDL 323
Query: 596 ATDLSNAFIDGDINTIVNILPEFVSLLLRCPQEMQTIAEDFLRCLSSAKQTDSVINANIA 655
TD+S+ + + L + L+R E++ E + K + + + A
Sbjct: 324 ETDISS------LKDRQSSLQSLSNSLIRRQGELEAGKETY------EKNRNHLSSLKEA 371
Query: 656 FQEKLKRLGEI 666
FQ K + L I
Sbjct: 372 FQHKFQGLSNI 382
>SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1957
Score = 35.0 bits (79), Expect = 0.38
Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 30/123 (24%)
Query: 494 ESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVK-------KLKSSAL 546
+S YQS++ LY +LR +H+N M+ + L E+ES++K + + +
Sbjct: 780 QSFTSLVNSYQSISNLYHELRDDHVN----MQSQNNTLLESESKLKTDCENLTQQNMTLI 835
Query: 547 SNVG--IRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFI 604
NV + + ES+ E K+ +G + SLD+ +L + L+ A
Sbjct: 836 DNVQKLMHKHVNQESKVSELKEVNGKL-----------------SLDLKNLRSSLNVAIS 878
Query: 605 DGD 607
D D
Sbjct: 879 DND 881
Score = 33.9 bits (76), Expect = 0.84
Identities = 36/154 (23%), Positives = 67/154 (43%), Gaps = 14/154 (9%)
Query: 483 DKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVK--- 539
DK+ Q+L + E +KE K+ +S L+++ LN KK + + L E + E++
Sbjct: 486 DKKDQELNNLREQIKEQKKVSESTQSSLQSLQRDILNEKKKHEVYESQLNELKGELQTEI 545
Query: 540 ---KLKSSALSNV------GIRNNNKGESEREEAKDRSGMILKSLVES--SIKSLQDPIA 588
+ SS LS + + NN+ + + + L +S +K + +
Sbjct: 546 SNSEHLSSQLSTLAAEKEAAVATNNELSESKNSLQTLCNAFQEKLAKSVMQLKENEQNFS 605
Query: 589 SLDVSDLATDLSNAFIDGDINTIVNILPEFVSLL 622
SLD S + S+ ++ + TI L + S L
Sbjct: 606 SLDTSFKKLNESHQELENNHQTITKQLKDTSSKL 639
Score = 33.5 bits (75), Expect = 1.1
Identities = 48/222 (21%), Positives = 95/222 (42%), Gaps = 25/222 (11%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
EKEA + + N++ KN Q + + +KL + +KE ++ + SL
Sbjct: 561 EKEAAV-----ATNNELSESKNSL---QTLCNAFQ---EKLAKSVMQLKENEQNFSSLDT 609
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
+ +L + H + + L + S++++L+ + K + +E D
Sbjct: 610 SFKKLNESHQELENNHQTITKQLKDTSSKLQQLQLERAN-----FEQKESTLSDENNDLR 664
Query: 569 GMILKSLVESSIKSL---QDPIASLD--VSDLATDLSNAFIDGDINTI-VNILPEFVSLL 622
+LK +E S KSL Q+ + SL+ + L DL + + + L E + L
Sbjct: 665 TKLLK--LEESNKSLIKKQEDVDSLEKNIQTLKEDLRKSEEALRFSKLEAKNLREVIDNL 722
Query: 623 LRCPQEMQTIAEDFLRCLSSAKQTDSVINANIA-FQEKLKRL 663
+ ++ D LS AK T++++++ + E +KRL
Sbjct: 723 KGKHETLEAQRNDLHSSLSDAKNTNAILSSELTKSSEDVKRL 764
Score = 33.1 bits (74), Expect = 1.4
Identities = 46/229 (20%), Positives = 91/229 (39%), Gaps = 29/229 (12%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELE-SVKEFKEKYQ-------S 505
++ ASLQ + N E Q +L R +LE E+ SV + + +
Sbjct: 1651 LEDSVASLQKECKIKSNTVESLQDVLTSVQARNAELEDEVSRSVDKIRRRDDRCEHLSGK 1710
Query: 506 LAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAK 565
L KL+SQL ++H + ++ L + VKK + L + +R +E+
Sbjct: 1711 LKKLHSQLEEQHETFFRAEQQRMTQLGFLKETVKK-QEKLLKKLNLR--------QEQLI 1761
Query: 566 DRSGMILKSL----VESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSL 621
RS +++ +E I LQ+ + +++S + + +L F
Sbjct: 1762 PRSSILVYESYIRDIEKEIIVLQERLNGIELSQQLPKGYFGYFFKTNRVEMEVLDSFKQQ 1821
Query: 622 L-----LRCPQEMQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKRLGE 665
+ L + + ED +C + K+ + + + EK++ LG+
Sbjct: 1822 VAKLQFLAGAEFIVKFKEDLEKCAAEEKEKQATFD---NYSEKVENLGK 1867
Score = 31.6 bits (70), Expect = 4.2
Identities = 41/216 (18%), Positives = 84/216 (37%), Gaps = 27/216 (12%)
Query: 461 LQNDIMSFKNQYERDQVMLEQYDKRVQK---LESELESVKEFKEKYQSLAK--------- 508
L++++ ++ + ++E R+ + L+SE +++ EK + L +
Sbjct: 303 LKHNVANYSDAIVHKDKLIEDLSTRISEFDNLKSERDTLSIKNEKLEKLLRNTIGSLKDS 362
Query: 509 --LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKD 566
SQL +E + + + + L +AES KL S N ++ + +KD
Sbjct: 363 RTSNSQLEEEMVELKESNRTIHSQLTDAES---KLSSFEQENKSLKGSIDEYQNNLSSKD 419
Query: 567 RSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFID----------GDINTIVNILP 616
+ + S +E + SL L + D N I +N+ N L
Sbjct: 420 KMVKQVSSQLEEARSSLAHATGKLAEINSERDFQNKKIKDFEKIEQDLRACLNSSSNELK 479
Query: 617 EFVSLLLRCPQEMQTIAEDFLRCLSSAKQTDSVINA 652
E +L+ + QE+ + E ++ T S + +
Sbjct: 480 EKSALIDKKDQELNNLREQIKEQKKVSESTQSSLQS 515
>Hs6857804 [Z] KOG4280 Kinesin-like protein
Length = 702
Score = 35.0 bits (79), Expect = 0.38
Identities = 26/99 (26%), Positives = 52/99 (52%), Gaps = 7/99 (7%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYER----DQVMLEQYDKRVQKLESELESVKEFKEKY 503
+EK + +++K D+++ + E+ + LE+ KR ++L ELE E +++
Sbjct: 472 LEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELE---EKEQER 528
Query: 504 QSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLK 542
+ + Y+ L++E KK+KK L A+SE+ L+
Sbjct: 529 LDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQ 567
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 35.0 bits (79), Expect = 0.38
Identities = 33/160 (20%), Positives = 78/160 (48%), Gaps = 25/160 (15%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
I+++ LQ+ I ++ + E++ + V L+ +LE +K+ + Q + SQL
Sbjct: 484 IEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQL 543
Query: 514 R---QEHLNILK-------KMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESERE- 562
+ +E ++L+ +++K+ +++++ S+++ L I N+K +++++
Sbjct: 544 QKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDY 603
Query: 563 ---------EAKDR---SGMILKSLVESSIKSLQDPIASL 590
E +DR S MI +++ I SLQ+ + L
Sbjct: 604 YQLQAILEAERRDRGHDSEMI--GDLQARITSLQEEVKHL 641
Score = 33.9 bits (76), Expect = 0.84
Identities = 22/95 (23%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query: 472 YERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDL 531
+E Q + + Q++ + +V +E L K LR+E+ + +KMKK +++
Sbjct: 914 FELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEY 973
Query: 532 -AEAESEVKKLKSSALSNVGIRNNNKGESEREEAK 565
E E E+ LK++ N+ K ++ + A+
Sbjct: 974 KLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAE 1008
>Hs4758646 [Z] KOG4280 Kinesin-like protein
Length = 747
Score = 35.0 bits (79), Expect = 0.38
Identities = 25/92 (27%), Positives = 52/92 (56%), Gaps = 11/92 (11%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKL 509
+E IQQ+ S + + K Y Q ++ K+++KL S+L++VK A++
Sbjct: 505 REREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVK---------AEI 555
Query: 510 YSQLRQEHLNILKKMKKTQDDLAEAESEVKKL 541
+ L++EH+ +++++TQ++L E ++K L
Sbjct: 556 HD-LQEEHIKERQELEQTQNELTR-ELKLKHL 585
>Hs4502395 [T] KOG2751 Beclin-like protein
Length = 450
Score = 35.0 bits (79), Expect = 0.38
Identities = 22/105 (20%), Positives = 55/105 (51%), Gaps = 10/105 (9%)
Query: 451 EALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKR-------VQKLESELESVKEFKEKY 503
E + + + LQ ++ + ER LE +K ++K+++E E + + + +Y
Sbjct: 170 EQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQY 229
Query: 504 QSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSN 548
Q + YS+ +++ L + ++K ++ + A++++ KLK + + N
Sbjct: 230 Q---REYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFN 271
>Hs20336209 [K] KOG1015 Transcription regulator XNP/ATRX DEAD-box superfamily
Length = 2492
Score = 35.0 bits (79), Expect = 0.38
Identities = 32/128 (25%), Positives = 60/128 (46%), Gaps = 12/128 (9%)
Query: 467 SFKNQYERDQVMLEQYDK--RVQKLESELESVKEFKEKYQSLAKLY------SQLRQEHL 518
S + ++D ++E D+ + Q+ + + V + K QS L ++ + +HL
Sbjct: 890 SAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHL 949
Query: 519 NILKKMKKTQDDLAE-AESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVE 577
K KK QD L++ AE +KK +S S + + KG E+++ D ++K +E
Sbjct: 950 KT-KTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIK--ME 1006
Query: 578 SSIKSLQD 585
+S D
Sbjct: 1007 QQYESSSD 1014
>Hs20336207 [K] KOG1015 Transcription regulator XNP/ATRX DEAD-box superfamily
Length = 2288
Score = 35.0 bits (79), Expect = 0.38
Identities = 32/128 (25%), Positives = 60/128 (46%), Gaps = 12/128 (9%)
Query: 467 SFKNQYERDQVMLEQYDK--RVQKLESELESVKEFKEKYQSLAKLY------SQLRQEHL 518
S + ++D ++E D+ + Q+ + + V + K QS L ++ + +HL
Sbjct: 686 SAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHL 745
Query: 519 NILKKMKKTQDDLAE-AESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVE 577
K KK QD L++ AE +KK +S S + + KG E+++ D ++K +E
Sbjct: 746 KT-KTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIK--ME 802
Query: 578 SSIKSLQD 585
+S D
Sbjct: 803 QQYESSSD 810
>Hs20336205 [K] KOG1015 Transcription regulator XNP/ATRX DEAD-box superfamily
Length = 2454
Score = 35.0 bits (79), Expect = 0.38
Identities = 32/128 (25%), Positives = 60/128 (46%), Gaps = 12/128 (9%)
Query: 467 SFKNQYERDQVMLEQYDK--RVQKLESELESVKEFKEKYQSLAKLY------SQLRQEHL 518
S + ++D ++E D+ + Q+ + + V + K QS L ++ + +HL
Sbjct: 852 SAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHL 911
Query: 519 NILKKMKKTQDDLAE-AESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVE 577
K KK QD L++ AE +KK +S S + + KG E+++ D ++K +E
Sbjct: 912 KT-KTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIK--ME 968
Query: 578 SSIKSLQD 585
+S D
Sbjct: 969 QQYESSSD 976
>CE16631 [Z] KOG0244 Kinesin-like protein
Length = 1083
Score = 35.0 bits (79), Expect = 0.38
Identities = 29/109 (26%), Positives = 53/109 (48%), Gaps = 20/109 (18%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLR 514
+QK Q + Q E ++ L R+ +LE+E+ +++ +K + AKL + R
Sbjct: 508 RQKALDEQRAFIEAMQQRESEKTQLVV---RISELETEMNKLRQEGKKVTTAAKLAEERR 564
Query: 515 Q-------EH------LNILKKMKKT----QDDLAEAESEVKKLKSSAL 546
Q +H LN +KK+++T ++ L + E E+K LK+ L
Sbjct: 565 QKLKDLERQHAEDKKVLNDMKKLQETRRRMEETLKKTEDELKNLKTQRL 613
>CE08691 [U] KOG0999 Microtubule-associated protein Bicaudal-D
Length = 869
Score = 35.0 bits (79), Expect = 0.38
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 11/98 (11%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQK-------LESELESV----KE 498
KE Q+ A L+ D+ + + + LE +K+ K LE E + KE
Sbjct: 97 KEEEYLQRIAKLEADLKKKEQELAEKKEELESIEKKHSKEIDSGAALEDERRKLRAELKE 156
Query: 499 FKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAES 536
KE+ Q L YS+L +E++ + K + + E ES
Sbjct: 157 TKEREQRLISEYSELEEENIGLQKTVANLRGSQVEYES 194
Score = 33.5 bits (75), Expect = 1.1
Identities = 25/108 (23%), Positives = 55/108 (50%), Gaps = 14/108 (12%)
Query: 456 QKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESEL----ESVKEFKEKYQSLAKLYS 511
Q S ++++ + ++ E E+Y +R+ KLE++L + + E KE+ +S+ K +S
Sbjct: 75 QHQRSTRSELENEESLLEESSAKEEEYLQRIAKLEADLKKKEQELAEKKEELESIEKKHS 134
Query: 512 Q-------LRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIR 552
+ L E + ++K+T++ SE +L+ N+G++
Sbjct: 135 KEIDSGAALEDERRKLRAELKETKEREQRLISEYSELEE---ENIGLQ 179
>CE00283 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation
Length = 834
Score = 35.0 bits (79), Expect = 0.38
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 42/218 (19%)
Query: 463 NDIMSFKNQYERDQVMLEQYDKRVQK----LESELESVKEFKEK---------YQSLAKL 509
N + S + +++ L + DK+ QK L+SEL S+KE ++K + +
Sbjct: 465 NTLRSMNRSLKSEKIRLREKDKQSQKDINTLKSELTSLKEAQDKCLLVPLEDVSNAPPED 524
Query: 510 YSQLRQEHLNILKKMKK-----TQDDLAEAESEVKKLKSSALSNV-GIRNNNKGESEREE 563
+++RQE+ ++ K++K+ Q+ + E EV + + LS + +R N+ + EE
Sbjct: 525 VNKIRQEYESLCKEVKRLGAMEKQEKQKQVEKEVNRQIADKLSELETLRKTNEMLTNDEE 584
Query: 564 A-KDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDI-NTIVNILPEFVSL 621
D I ++ E ++ Q I + D + N D I N N L E +S
Sbjct: 585 CISDELEAIGTAVEEEQERNAQLYIEKREQEDRNLKMMN---DRMIQNQTFNRLREKLS- 640
Query: 622 LLRCPQEMQTIAEDFLRCLSSAKQTDSVINANIAFQEK 659
CL S QTD+ I F++K
Sbjct: 641 -----------------CLESKAQTDAQIAKMHEFEKK 661
>At3g44800 [DR] KOG1987 Speckle-type POZ protein SPOP and related proteins
with TRAF MATH and BTB/POZ domains
Length = 507
Score = 35.0 bits (79), Expect = 0.38
Identities = 32/108 (29%), Positives = 49/108 (44%), Gaps = 2/108 (1%)
Query: 452 ALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYS 511
+LI+ SLQ+ + Q E+ L+ +V LE +LE VKE K+ + + K
Sbjct: 196 SLIKTLCQSLQDISIDDLGQTEQVLTFLQNSGFKVDWLERKLEEVKE-KKIQEHIGKSRM 254
Query: 512 QLRQEHLNILKKMKKTQDDLAEAE-SEVKKLKSSALSNVGIRNNNKGE 558
Q +E L + KK + L E E E+K LK + KG+
Sbjct: 255 QGLEEDLKVFKKKCSDIEALLEKEKEELKGLKQKCSDIEALLEKEKGK 302
>At2g38720 [DZ] KOG4302 Microtubule-associated protein essential for anaphase
spindle elongation
Length = 587
Score = 35.0 bits (79), Expect = 0.38
Identities = 33/135 (24%), Positives = 63/135 (46%), Gaps = 11/135 (8%)
Query: 465 IMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKM 524
+ S K + + L+ + +Q+L + +E+ + + ++ + L S L + LKK
Sbjct: 226 VKSLKAEKHERLLKLQGLGRSMQELWNLMETPMDERRRFDHCSSLLSSLPDD---ALKKG 282
Query: 525 KKTQDDLAEAESEVKK---LKSSALSNVGIRNNNKGE-----SEREEAKDRSGMILKSLV 576
+ D + EAE EV++ LKSS + + + + E + + D + L L+
Sbjct: 283 CLSLDIIREAEDEVRRLNSLKSSKMKELVFKRQCELEEICRGNHMDINSDAARKSLVELI 342
Query: 577 ESSIKSLQDPIASLD 591
ES L D +AS+D
Sbjct: 343 ESGDGDLSDILASID 357
>7303885 [U] KOG4809 Rab6 GTPase-interacting protein involved in
endosome-to-TGN transport
Length = 1456
Score = 35.0 bits (79), Expect = 0.38
Identities = 29/102 (28%), Positives = 49/102 (47%), Gaps = 11/102 (10%)
Query: 452 ALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSL---AK 508
A +Q++ +L D + + E+ QV L + K + ELE++KE E Q+L A
Sbjct: 482 ARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAA 541
Query: 509 LYSQLRQEHLNILKK--------MKKTQDDLAEAESEVKKLK 542
+ Q L +LK+ +K Q + +A +EV+ LK
Sbjct: 542 RDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILK 583
Score = 30.8 bits (68), Expect = 7.1
Identities = 35/161 (21%), Positives = 71/161 (43%), Gaps = 34/161 (21%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVK--------------EFK 500
Q A Q + S + ++ER L + R++K E+E E+++ + +
Sbjct: 929 QMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRSGGAGAAPHPQLE 988
Query: 501 EKYQSLAKLYSQLRQEHLNILKKMKKTQD-------DLAEAESEVKKLKSSALSNVGIRN 553
+ Q L QL E ++ +++K+Q+ +L AE+E++K + N +RN
Sbjct: 989 KHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTRE---ENRKLRN 1045
Query: 554 NNK---------GESERE-EAKDRSGMILKSLVESSIKSLQ 584
++ G S E +A + L+ ++ S ++LQ
Sbjct: 1046 GHQVPPVAAPPAGPSPAEFQAMQKEIQTLQQKLQESERALQ 1086
Score = 30.4 bits (67), Expect = 9.3
Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 26/109 (23%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLES--------------ELE 494
E+ A +Q+K Q ++ K + E Q E + ++K +S E+E
Sbjct: 346 EEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVE 405
Query: 495 SVKEFKEKYQ-SLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLK 542
+KE E+ Q +L K SQL+ E K Q+ L +A++EV L+
Sbjct: 406 KIKEEMERTQATLGK--SQLQHE---------KLQNSLDKAQNEVDHLQ 443
>7303561 [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 2346
Score = 35.0 bits (79), Expect = 0.38
Identities = 31/135 (22%), Positives = 67/135 (48%), Gaps = 12/135 (8%)
Query: 458 TASLQNDIMSFKNQYERD-QVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQE 516
T +L ++ ++ N+ R+ ++ L+Q ++ L EL +E E++ ++ Q
Sbjct: 918 TPTLNDNPITAANKRAREFELKLDQATVEIESLTKELAKTREHGEQFYKMS-------QS 970
Query: 517 HLNILKKMKKTQDDL-AEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSL 575
+ +K++ + +L A+ E E+KKL+SS ++ + E+ ++S + +S
Sbjct: 971 AESEIKRLHELHGELVAKQEEEIKKLRSSEAELKTRISDLEAEAMLSNVTEQSKTVNQS- 1029
Query: 576 VESSIKSLQDPIASL 590
+KS QD + SL
Sbjct: 1030 --GQLKSAQDDLKSL 1042
Score = 32.0 bits (71), Expect = 3.2
Identities = 33/151 (21%), Positives = 68/151 (44%), Gaps = 23/151 (15%)
Query: 455 QQKTASLQNDIMSFKNQYERDQV-----MLEQYDKRVQKLESEL-----------ESVKE 498
QQ + L N + K ER ++ + ++ D V++L ++ ES+ E
Sbjct: 807 QQSQSLLLNSLEFIKTNLERSEMEGRQRLEQRLDDTVRELAAQRRHFQEEEEKFRESINE 866
Query: 499 FKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLK-------SSALSNVGI 551
FK + ++ KL + +Q ++ +++LAE ++V +L + L++ I
Sbjct: 867 FKRQAETAIKLKDEEKQLADKWQAELTSVREELAEKVNKVNELSKKLQEVLTPTLNDNPI 926
Query: 552 RNNNKGESEREEAKDRSGMILKSLVESSIKS 582
NK E E D++ + ++SL + K+
Sbjct: 927 TAANKRAREFELKLDQATVEIESLTKELAKT 957
>SPAC1486.04c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1727
Score = 34.7 bits (78), Expect = 0.49
Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 11/126 (8%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E+EAL++ + LQ+ S ++QY +EQ + E +E VK ++Y+ +
Sbjct: 912 EREALLESSLSDLQSKHTSLESQYNYSLRNIEQLQAASKLAEEMVERVKTEYDEYR--LQ 969
Query: 509 LYSQLRQEHLNIL---KKMKKTQDDLAEAESEVKKLKSSALSNVGI------RNNNKGES 559
L + HL I +++ QD++A + + + + + V + NN+ S
Sbjct: 970 TSESLEKNHLKITSLEQRIVILQDEIASSSLRCENITKDSETRVALLLEENKHLNNELSS 1029
Query: 560 EREEAK 565
R K
Sbjct: 1030 HRNAEK 1035
>Hs7662208 [T] KOG1451 Oligophrenin-1 and related Rho GTPase-activating
proteins
Length = 814
Score = 34.7 bits (78), Expect = 0.49
Identities = 17/49 (34%), Positives = 31/49 (62%), Gaps = 2/49 (4%)
Query: 490 ESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEV 538
+ ++ + KE K+KY + Y + ++HLN+ K K++Q L EA+S+V
Sbjct: 121 KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQ--LQEADSQV 167
>Hs5453591 [BD] KOG0933 Structural maintenance of chromosome protein 2
(chromosome condensation complex Condensin subunit E)
Length = 1197
Score = 34.7 bits (78), Expect = 0.49
Identities = 20/77 (25%), Positives = 42/77 (53%), Gaps = 4/77 (5%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLR 514
QQ+ + Q ++ + Y +DQ LE + +KLE+E++ + + K +SL + QL
Sbjct: 427 QQELKNKQAEVKKMDSGYRKDQEALEAVKRLKEKLEAEMKKLNYEENKEESLLEKRRQLS 486
Query: 515 QEHLNILKKMKKTQDDL 531
++ + ++K+T + L
Sbjct: 487 RD----IGRLKETYEAL 499
Score = 31.6 bits (70), Expect = 4.2
Identities = 19/113 (16%), Positives = 59/113 (51%), Gaps = 3/113 (2%)
Query: 455 QQKTASLQNDIMSFKNQYERD-QVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
++K L+N + + + + ER+ + ++ D K ++ + +KE +++ +++ +L
Sbjct: 770 EEKYEVLENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEEL 829
Query: 514 RQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKD 566
++EH + ++++ + + ES+++ + + N + NK + E + K+
Sbjct: 830 KREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNK--ESVNKAQEEVTKQKE 880
>Hs18644730 [B] KOG1973 Chromatin remodeling protein contains PHD Zn-finger
Length = 240
Score = 34.7 bits (78), Expect = 0.49
Identities = 22/89 (24%), Positives = 45/89 (49%), Gaps = 7/89 (7%)
Query: 480 EQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVK 539
+Q +R+QK+++ KE+ + LA ++ +H+ ++ DLA E+++K
Sbjct: 59 DQRVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHI------RRLDADLARFEADLK 112
Query: 540 -KLKSSALSNVGIRNNNKGESEREEAKDR 567
K++ S + G R KG ++E+ R
Sbjct: 113 DKMEGSDFESSGGRGLKKGRGQKEKRGSR 141
>CE26070 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 2083
Score = 34.7 bits (78), Expect = 0.49
Identities = 32/108 (29%), Positives = 51/108 (46%), Gaps = 8/108 (7%)
Query: 473 ERDQVMLEQYDKRVQKLESELESVK--EFKEKYQSLAKLYSQLRQEHLNILKKM--KKTQ 528
E D+ ++ QKLESE+ + K E K K ++ AK + E K+ KK
Sbjct: 1506 EADKAHKQKESDEKQKLESEIAAKKSAEQKSKLETEAKTKKVIEDESAKKQKEQEDKKKG 1565
Query: 529 DDLAEAESEVK---KLKSSALSNVGIRNNNKGE-SEREEAKDRSGMIL 572
DD A+ + + K KL+S A S K E + +E+AK + ++
Sbjct: 1566 DDSAKKQKDQKEKQKLESEATSKKPTSEKQKDEKTPQEKAKSENETVM 1613
Score = 33.9 bits (76), Expect = 0.84
Identities = 34/147 (23%), Positives = 61/147 (41%), Gaps = 11/147 (7%)
Query: 475 DQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEA 534
D ++ K QKLESE S K EK + + + E+ ++ T+ E
Sbjct: 1567 DSAKKQKDQKEKQKLESEATSKKPTSEKQKDEKTPQEKAKSENETVM----TTEPQQLEV 1622
Query: 535 ESEVKKLKSSAL--SNVGIRNNNKGESEREEAKDRSGMILK----SLVESSIKSLQDPIA 588
+SE KK + V +S+ +E K++ +I K + + + K L +
Sbjct: 1623 KSEPKKSDKTETVEKEVASSTEKSDDSKTKEPKEKKKIIKKKKDTTKPQEASKELSSDES 1682
Query: 589 SLDV-SDLATDLSNAFIDGDINTIVNI 614
+D+ SD++ L D++T I
Sbjct: 1683 RIDLESDISLSLDTVTESDDLSTASTI 1709
Score = 32.0 bits (71), Expect = 3.2
Identities = 30/120 (25%), Positives = 50/120 (41%), Gaps = 9/120 (7%)
Query: 469 KNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQ 528
K E D V E+ QKLESE + K EK KL Q +++ + +K Q
Sbjct: 1365 KKAAEADAVKKEKELAEKQKLESEAATKKAAAEK----LKLEEQKKKDAETASIEKQKEQ 1420
Query: 529 DDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDR-----SGMILKSLVESSIKSL 583
+ LA+ +S+++ + + + K + E K+ +LK E S S+
Sbjct: 1421 EKLAQEQSKLEVDAKKSAEKQKLESETKSKKTEEAPKESVDEKPKKKVLKKKTEKSDSSI 1480
>CE07306 [Z] KOG0161 Myosin class II heavy chain
Length = 1974
Score = 34.7 bits (78), Expect = 0.49
Identities = 23/120 (19%), Positives = 53/120 (44%), Gaps = 1/120 (0%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
+++ L + + + Q E + +K Q+L +LE + ++ S+A +
Sbjct: 1396 LEETRRKLTHKVQEMQEQLENANQKIGTLEKNKQRLAHDLEDAQVDADRANSIASSLEKK 1455
Query: 514 RQEHLNILKKMKKTQDDL-AEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMIL 572
++ +L + ++ + L AE E ++ +++A +RN + E+ EA R L
Sbjct: 1456 QKGFDKVLDEWRRKCEALVAEVEQSQRETRAAATETFRLRNQLEESGEQTEAVKRENKAL 1515
Score = 31.6 bits (70), Expect = 4.2
Identities = 36/173 (20%), Positives = 77/173 (43%), Gaps = 25/173 (14%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKE--------------- 498
+ + A L++ + ++ ER++ + +K+ +K+E EL+ +E
Sbjct: 1030 LNKTKAKLESTLDELEDTLEREKRGRQDCEKQRRKVEGELKIAQELIEELNRHKHEQEQV 1089
Query: 499 FKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLA---EAESEVKKLKSSALSNVGIRNNN 555
K+K L+ + S+L E + K ++ ++ LA E E E+ ++S RN
Sbjct: 1090 IKKKDIELSSIQSRLEDEQSLVAKLQRQIKELLARIQELEEELDAERNSRSKAEKARNEM 1149
Query: 556 KGE-SEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGD 607
+ E E + D +G ++ +E + K +++ L DL +A I+ +
Sbjct: 1150 QMELEELGDRLDEAGGATQAQIELNKK------REAELAKLRQDLEDAAINSE 1196
>CE04747 [OE] KOG1282 Serine carboxypeptidases (lysosomal cathepsin A)
Length = 2338
Score = 34.7 bits (78), Expect = 0.49
Identities = 27/88 (30%), Positives = 38/88 (42%), Gaps = 18/88 (20%)
Query: 331 SPVHEAPPVARPAEVRSLSQPAAP---VVPIATGVVMPVVTGYSQ------------PPL 375
SPV +APPV P + + P P VVP+++ V+ + PP
Sbjct: 2218 SPVTQAPPVTLPPPSVATAGPTGPILTVVPVSSAPTSGAVSSTTNTPSPTNQSPVTLPPP 2277
Query: 376 QVV---PTGAEFWSIPSTSAPTRSVVAS 400
V PTG +P +SAPT V+S
Sbjct: 2278 SVATAGPTGPILTVVPVSSAPTSGAVSS 2305
>CE03710 [S] KOG2911 Uncharacterized conserved protein
Length = 411
Score = 34.7 bits (78), Expect = 0.49
Identities = 25/101 (24%), Positives = 50/101 (48%), Gaps = 10/101 (9%)
Query: 465 IMSFKNQYERDQVMLEQYD-------KRVQKLESELESVKEFKEKY--QSLAKLYSQLRQ 515
++ FK+ D V + D K + KL+ E++ +++ +KY Q A L + +
Sbjct: 197 VLKFKDNGSEDPVKFTEADASVVDIRKAMNKLDREIQQLEQKVKKYDEQCRACLRTGDKG 256
Query: 516 EHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNK 556
N L++ K+ + D+A+ + + +KL + L + NNK
Sbjct: 257 RAQNFLRQRKRAEKDIADKDVQYQKL-LTMLHQISSAKNNK 296
>At3g47460 [BD] KOG0933 Structural maintenance of chromosome protein 2
(chromosome condensation complex Condensin subunit E)
Length = 1171
Score = 34.7 bits (78), Expect = 0.49
Identities = 43/229 (18%), Positives = 106/229 (45%), Gaps = 24/229 (10%)
Query: 463 NDIMSFKNQYERDQVMLEQYD---KRVQKLESELESVK-EFKEKYQSLAKLYSQLRQ-EH 517
+D+ + ++ Q L + + K +Q L+++ +K + + K ++ + Q EH
Sbjct: 674 HDLAEAETKFRAHQKSLSEIEANIKELQPLQTKFTDMKAQLELKMYDMSLFLKRAEQNEH 733
Query: 518 LNILKKMKKTQDDLAEAESEVKK---LKSSALSNV-----GIRNNNKGESEREEAKDRSG 569
+ +KK ++++ E S++K+ L S V I++++K R + +++
Sbjct: 734 HKLGDAVKKLEEEVEEMRSQIKEKEGLYKSCADTVSTLEKSIKDHDKNREGRLKDLEKNI 793
Query: 570 MILKSLVESSIKSL---QDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCP 626
LK+ +++S K L ++ L + A +++ + ++ + S +
Sbjct: 794 KTLKARIQASSKDLKGHENVRERLVMEQEAVTQEQSYLKSQLTSLRTQISTLASDVGNQR 853
Query: 627 QEMQTIAEDFLRCLS-------SAKQTDSVINANIAFQEK-LKRLGEIR 667
++ I +D + LS K+ D+ I+ +IA QEK L+++ +++
Sbjct: 854 AKVDAIQKDHDQSLSELKLIHAKMKECDTQISGSIAEQEKCLQKISDMK 902
>At3g44790 [DR] KOG1987 Speckle-type POZ protein SPOP and related proteins
with TRAF MATH and BTB/POZ domains
Length = 324
Score = 34.7 bits (78), Expect = 0.49
Identities = 30/89 (33%), Positives = 44/89 (48%), Gaps = 3/89 (3%)
Query: 452 ALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYS 511
+LI SLQ+ + Q E+ L+ D +V LE +LE VKE K+ + + K
Sbjct: 209 SLIDTLCQSLQDISIDDLGQAEKALRYLKDSDFKVDWLERKLEEVKE-KKMEEQIGKSRM 267
Query: 512 QLRQEHLNILKKMKKTQDDLAEAESEVKK 540
Q +E L I K +K D A+ E E +K
Sbjct: 268 QELEEELKIFK--QKCSDIEAQLEKEKQK 294
>At2g31970 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC
superfamily
Length = 1292
Score = 34.7 bits (78), Expect = 0.49
Identities = 33/165 (20%), Positives = 74/165 (44%), Gaps = 34/165 (20%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESE------------LESV 496
EK+ ++ + + QN F+++ E+ Q + + +++ L E L +
Sbjct: 484 EKQVQVELERKTKQNSERGFESKIEQKQHEIYSLEHKIKTLNRERDVMAGDAEDRLLTRI 543
Query: 497 KEFKEKYQSLAK----LYSQLRQEHLNILKKMKKTQDDLA----EAESEVK--KLKSSAL 546
E K++ + + K +++E + L+ +++ DDL+ EAE EV ++K +
Sbjct: 544 DECKDRIRGVLKGRLPPEKDMKREIVQALRSIEREYDDLSLKSREAEKEVNMLQMKIQEV 603
Query: 547 SNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLD 591
+N ++N ES K +ES +++L+ ++D
Sbjct: 604 NNSLFKHNKDTESR------------KRYIESKLQALKQESVTID 636
Score = 32.7 bits (73), Expect = 1.9
Identities = 32/151 (21%), Positives = 71/151 (46%), Gaps = 33/151 (21%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYE-RDQVMLE-------------QYDKRVQKLESEL 493
+E E +Q+ A + N M K+ + +DQV ++ QY ++ E +
Sbjct: 243 LELETSVQKVDAEVHNKEMMLKDLRKLQDQVSIKTAERSTLFKEQQRQYAALPEENEDTI 302
Query: 494 ESVKEFKEKYQSLAKLYSQLRQEHLNIL-KKMKKTQDDLAEAESEVKKLKSSALSNVGIR 552
E +KE+K K+ +E L +L K++K + ++ + E+ + L ++ +
Sbjct: 303 EELKEWKSKF-----------EERLALLGTKIRKMEREMVDTETTISSLHNA-------K 344
Query: 553 NNNKGESEREEAKDRSGMILKSLVESSIKSL 583
N E + + + + M+LK+ +S+I+++
Sbjct: 345 TNYMLEISKLQTEAEAHMLLKNERDSTIQNI 375
>At1g79830 [K] KOG4673 Transcription factor TMF TATA element modulatory factor
Length = 918
Score = 34.7 bits (78), Expect = 0.49
Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 14/128 (10%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
+ +K A+ + I + Q + E+ + KL+SE V+ K + KL +
Sbjct: 455 LSKKQAAQEAQIRKLRAQIREAE---EEKKGLITKLQSEENKVESIKRDKTATEKLLQET 511
Query: 514 RQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESERE----EAKDRSG 569
++H L K + A E + L R NN+ SE E EA +R
Sbjct: 512 IEKHQAELTSQKDYYSNALAAAKEAQALAEE-------RTNNEARSELENRLKEAGERES 564
Query: 570 MILKSLVE 577
M++++L E
Sbjct: 565 MLVQALEE 572
>At1g03830 [R] KOG2037 Guanylate-binding protein
Length = 991
Score = 34.7 bits (78), Expect = 0.49
Identities = 21/106 (19%), Positives = 53/106 (49%), Gaps = 2/106 (1%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKE-FKEKYQSL 506
M + + ++ + SL++ + K Q E + M ++Y KR + ++ + + FK + L
Sbjct: 401 MSENSKLKLQQQSLESTMNLLKKQLEGREKMNKEYQKRYESAIDDICKLSDQFKNRINDL 460
Query: 507 AKLYSQLRQEHLNILKKMKKTQDDLAEAESEVK-KLKSSALSNVGI 551
+ EH N+++ + T+ + +E + + + L + +SN+ +
Sbjct: 461 ESKCKSIHDEHSNLMEVLGSTRLEASEWKRKYEGTLDENGVSNIRV 506
>YLR045c [Z] KOG1820 Microtubule-associated protein
Length = 888
Score = 34.3 bits (77), Expect = 0.64
Identities = 35/165 (21%), Positives = 73/165 (44%), Gaps = 17/165 (10%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESE-----------LESVK 497
+ L+ K+ + ++++ N ++++ ++E+Y R+QKL+++ LE +
Sbjct: 633 KSRVLLTSKSLATPKNVVA--NSTDKNEKLIEEYKYRLQKLQNDEMIWTKERQSLLEKMN 690
Query: 498 EFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKG 557
+ + K LR++ K+ + L E +V KL LS N +
Sbjct: 691 NTENYKIEMIKENEMLREQLKEAQSKLNEKNIQLRSKEIDVNKLSDRVLSLENELRNMEI 750
Query: 558 ESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNA 602
E +R K R+ L+S+ +I S P +++ + LS+A
Sbjct: 751 ELDRN--KKRNDTNLQSM--GTISSYSIPSSTVSSNYGVKSLSSA 791
>Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein
Length = 742
Score = 34.3 bits (77), Expect = 0.64
Identities = 37/198 (18%), Positives = 86/198 (42%), Gaps = 13/198 (6%)
Query: 456 QKTASLQNDIMSFKNQYERDQVMLEQYD---KRVQKLESELESVKEFKEKYQSLAKLYSQ 512
++ L+N++ + + E Q + ++++ LE E ++ K + +
Sbjct: 550 ERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKN 609
Query: 513 LRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKG-ESEREEAKDRSGMI 571
L + ++ K+ + ++ E V+ LK +++ ++ NK ESE+E+ K G+
Sbjct: 610 LTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLK--KGL- 666
Query: 572 LKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCPQEMQT 631
L+++S K + L+VS D+ N + + + + S L E QT
Sbjct: 667 --ELLKASFKKTE----RLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQT 720
Query: 632 IAEDFLRCLSSAKQTDSV 649
+ ++ S+K+ + +
Sbjct: 721 LQKNLEELKISSKRLEQL 738
>Hs8923699 [S] KOG4725 Uncharacterized conserved protein
Length = 693
Score = 34.3 bits (77), Expect = 0.64
Identities = 28/128 (21%), Positives = 56/128 (42%), Gaps = 12/128 (9%)
Query: 481 QYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESE--- 537
QY + LES ++ + E +SL + Q+ + L++ KKT +++ +A+ E
Sbjct: 70 QYQELAVALESSSVTINQLNENIESLKQQKKQVEHQ----LEEAKKTNNEIHKAQMEQLE 125
Query: 538 ---VKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSD 594
+ L+ + L EE+KD +G + SL I+ L+ + ++
Sbjct: 126 TINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSL--QRIQELERALCAVSTQQ 183
Query: 595 LATDLSNA 602
D S++
Sbjct: 184 QEEDRSSS 191
>Hs7661992 [KRT] KOG4572 Predicted DNA-binding transcription factor interacts
with stathmin
Length = 1591
Score = 34.3 bits (77), Expect = 0.64
Identities = 29/146 (19%), Positives = 70/146 (47%), Gaps = 6/146 (4%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLA 507
+E + +Q A LQ+ S + E D + + + + + S++E K++ Q
Sbjct: 967 VENDEKLQLLRAELQSLEQSHLKELE-DTLQVRHIQEFEKVMTDHRVSLEELKKENQ--- 1022
Query: 508 KLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESE--REEAK 565
++ +Q+++ H I+++ +K +L S++ + + ++ E + EE++
Sbjct: 1023 QIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESR 1082
Query: 566 DRSGMILKSLVESSIKSLQDPIASLD 591
+ LKSL+E ++L+ I+ L+
Sbjct: 1083 AQQKETLKSLLEQETENLRTEISKLN 1108
>Hs6912568 [DK] KOG4333 Nuclear DEAF-1 related transcriptional regulator
(suppressin) and related SAND domain proteins
Length = 530
Score = 34.3 bits (77), Expect = 0.64
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 1/61 (1%)
Query: 331 SPVHEAPPVARPAEVRSLSQPAAPVVPIAT-GVVMPVVTGYSQPPLQVVPTGAEFWSIPS 389
+PV PPV RP R+ S PAA + T + + G P L VP G ++PS
Sbjct: 348 TPVSLPPPVKRPRLARATSGPAAMASQVLTQSAQLALGPGVPVPQLTSVPLGKVVSTLPS 407
Query: 390 T 390
T
Sbjct: 408 T 408
>Hs5453758 [Z] KOG1702 Nebulin repeat protein
Length = 1014
Score = 34.3 bits (77), Expect = 0.64
Identities = 34/149 (22%), Positives = 71/149 (46%), Gaps = 16/149 (10%)
Query: 451 EALIQQKTASLQNDIMSFKNQYERDQ--VMLE-------QYDKRVQKLESELESVKEFKE 501
E L + A LQ+ + +K +YE+++ MLE Q K QK++SE ++F++
Sbjct: 323 EHLHHKGNAVLQSQV-KYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEK 381
Query: 502 KYQSLAKLYSQLRQE--HLNILKKMKKTQDDLAEAESEVK----KLKSSALSNVGIRNNN 555
+ + + L E H+ + + + ++ + E+E+K +L S L + +
Sbjct: 382 EIKGRSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRAS 441
Query: 556 KGESEREEAKDRSGMILKSLVESSIKSLQ 584
+ SE+E KD +I +++ +L+
Sbjct: 442 EMASEKEYKKDLESIIKGKGMQAGTDTLE 470
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 34.3 bits (77), Expect = 0.64
Identities = 45/239 (18%), Positives = 106/239 (43%), Gaps = 24/239 (10%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYE--RDQVMLEQYDKRVQKLESELESVKEFKEKYQS 505
ME + ++++ A L+ + Q + +DQ+ EQY + K + V+E KE+ +
Sbjct: 835 MEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQ-----VRELKEECEE 889
Query: 506 LAKLYSQLRQEHLNILKKMKKTQDDL-AEAESEVKKLKSSALSNVGIRNNNKGESEREEA 564
KL +L+Q+ ++++ +D L A+ E + K S L+ I + E+E+
Sbjct: 890 KTKLGKELQQKK----QELQDERDSLAAQLEITLTKADSEQLAR-SIAEEQYSDLEKEK- 943
Query: 565 KDRSGMILKSL-VESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLL 623
I+K L ++ + + + D + + + +N + D+ + N E + L
Sbjct: 944 ------IMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLK 997
Query: 624 RCPQEMQTIAEDFLRCLSSAKQTD-SVINANIAFQEKLKRLGEI--RQYSYRYGDSDEV 679
+++ + ++ + + Q + ++ + + +L EI R+ + G+ +V
Sbjct: 998 DVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDV 1056
>Hs4758956 [TZ] KOG3632 Peripheral benzodiazepine receptor PRAX-1
Length = 1857
Score = 34.3 bits (77), Expect = 0.64
Identities = 32/143 (22%), Positives = 69/143 (47%), Gaps = 32/143 (22%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
EKE ++ + A L+ ++ ERD + ++ Q L+S+LES+++ + + +A+
Sbjct: 395 EKEQ-VEWENAELRGQLLGVTQ--ERDSAL-----RKSQGLQSKLESLEQVLKHMREVAQ 446
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
QL EH ++ + L E + EV++L+ +++ E ++
Sbjct: 447 RRQQLEVEH-------EQARLSLREKQEEVRRLQ---------------QAQAEAQREHE 484
Query: 569 GMILKSLVESSIKSLQDPIASLD 591
G + L+ES++ S+Q + L+
Sbjct: 485 GAV--QLLESTLDSMQARVRELE 505
>Hs4505877 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein) and related
proteins
Length = 4574
Score = 34.3 bits (77), Expect = 0.64
Identities = 27/117 (23%), Positives = 60/117 (51%), Gaps = 6/117 (5%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKL-ESELESVKEFKEKYQSL 506
+++E L+Q+ T +LQ +S K+ + + +EQ ++++L + E+ ++ +E+ Q
Sbjct: 2506 VQQEQLLQE-TQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQ-- 2562
Query: 507 AKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREE 563
+ Q+ QE ++ M++ + EAE V++ K L + + + E EE
Sbjct: 2563 -RQQQQMEQERQRLVASMEEARRRQHEAEEGVRR-KQEELQQLEQQRRQQEELLAEE 2617
>Hs4503169 [K] KOG0963 Transcription factor/CCAAT displacement protein CDP1
Length = 678
Score = 34.3 bits (77), Expect = 0.64
Identities = 19/71 (26%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
Query: 479 LEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEV 538
LE+Y+K +++++ ++K KEK + + Q L+K +K Q+D AE E ++
Sbjct: 133 LEEYNKEFAEVKNQEVTIKALKEKIREYEQTLK--NQAETIALEKEQKLQNDFAEKERKL 190
Query: 539 KKLKSSALSNV 549
++ + S S +
Sbjct: 191 QETQMSTTSKL 201
>Hs22056365 [S] KOG4725 Uncharacterized conserved protein
Length = 693
Score = 34.3 bits (77), Expect = 0.64
Identities = 28/128 (21%), Positives = 56/128 (42%), Gaps = 12/128 (9%)
Query: 481 QYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESE--- 537
QY + LES ++ + E +SL + Q+ + L++ KKT +++ +A+ E
Sbjct: 70 QYQELAVALESSSVTINQLNENIESLKQQKKQVEHQ----LEEAKKTNNEIHKAQMEQLE 125
Query: 538 ---VKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSD 594
+ L+ + L EE+KD +G + SL I+ L+ + ++
Sbjct: 126 TINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSL--QHIQELERALCAVSTQQ 183
Query: 595 LATDLSNA 602
D S++
Sbjct: 184 QEEDRSSS 191
>Hs22045440 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 636
Score = 34.3 bits (77), Expect = 0.64
Identities = 41/155 (26%), Positives = 76/155 (48%), Gaps = 28/155 (18%)
Query: 468 FKNQYERDQVMLEQYDKRVQKLESEL------------------ESVKEFKEKYQSLAKL 509
FK QYER++V+L + +K KL SEL E VK+ +K +S+A
Sbjct: 373 FKQQYEREKVLLTEENK---KLTSELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHW 429
Query: 510 YSQLRQEHLNILKKMKKTQDDL-AEAESEVKKLKSSALSNVGIRNNNKGESEREEAK-DR 567
+Q+ E + + K + L A A ++L++ S++G R + R AK D
Sbjct: 430 EAQI-TEIIQWVSDEKDARGYLQALASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDM 488
Query: 568 SGMI-LKSLVESSIK---SLQDPIASLDVSDLATD 598
S + L+S +++ I+ ++Q+ + + S++ T+
Sbjct: 489 SARLELQSALDAEIRAKQAIQEELNKVKASNIITE 523
>Hs21735417 [U] KOG0999 Microtubule-associated protein Bicaudal-D
Length = 824
Score = 34.3 bits (77), Expect = 0.64
Identities = 55/246 (22%), Positives = 106/246 (42%), Gaps = 38/246 (15%)
Query: 450 KEALIQQKTASLQNDIMSFKN-----QYERDQVM-----LEQYDKRVQKLESEL-ESVKE 498
KE +K LQ ++ +N Q E +++ L++ ++ V+ L + +KE
Sbjct: 110 KEQYYVRKVLELQTELKQLRNVLTNTQSENERLASVAQELKEINQNVEIQRGRLRDDIKE 169
Query: 499 FKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAES---EVKKLK------SSALSNV 549
+K + L + YS+L +E++++ K++ + + E E E+K+L+ +S L +
Sbjct: 170 YKFREARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLED- 228
Query: 550 GIRNNNKGESEREEA-------KDRSGMILKSLVESSIKSLQDPI------ASLDVSDLA 596
IR E + EEA +++ + K L S S+ D SLD +
Sbjct: 229 AIRLKEISERQLEEALETLKTEREQKNSLRKEL--SHYMSINDSFYTSHLHVSLDGLKFS 286
Query: 597 TDLSNAFIDGDINTIVNILPEFVSLLLRCPQEMQTIAEDFLRCLSSAKQTDSVINANIAF 656
D + + D +VN L + T ++ L S + +D + NI+
Sbjct: 287 DDAAEP--NNDAEALVNGFEHGGLAKLPLDNKTSTPKKEGLAPPSPSLVSDLLSELNISE 344
Query: 657 QEKLKR 662
+KLK+
Sbjct: 345 IQKLKQ 350
>Hs20540694 [U] KOG0999 Microtubule-associated protein Bicaudal-D
Length = 855
Score = 34.3 bits (77), Expect = 0.64
Identities = 55/246 (22%), Positives = 106/246 (42%), Gaps = 38/246 (15%)
Query: 450 KEALIQQKTASLQNDIMSFKN-----QYERDQVM-----LEQYDKRVQKLESEL-ESVKE 498
KE +K LQ ++ +N Q E +++ L++ ++ V+ L + +KE
Sbjct: 110 KEQYYVRKVLELQTELKQLRNVLTNTQSENERLASVAQELKEINQNVEIQRGRLRDDIKE 169
Query: 499 FKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAES---EVKKLK------SSALSNV 549
+K + L + YS+L +E++++ K++ + + E E E+K+L+ +S L +
Sbjct: 170 YKFREARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLED- 228
Query: 550 GIRNNNKGESEREEA-------KDRSGMILKSLVESSIKSLQDPI------ASLDVSDLA 596
IR E + EEA +++ + K L S S+ D SLD +
Sbjct: 229 AIRLKEISERQLEEALETLKTEREQKNSLRKEL--SHYMSINDSFYTSHLHVSLDGLKFS 286
Query: 597 TDLSNAFIDGDINTIVNILPEFVSLLLRCPQEMQTIAEDFLRCLSSAKQTDSVINANIAF 656
D + + D +VN L + T ++ L S + +D + NI+
Sbjct: 287 DDAAEP--NNDAEALVNGFEHGGLAKLPLDNKTSTPKKEGLAPPSPSLVSDLLSELNISE 344
Query: 657 QEKLKR 662
+KLK+
Sbjct: 345 IQKLKQ 350
>Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 34.3 bits (77), Expect = 0.64
Identities = 45/239 (18%), Positives = 106/239 (43%), Gaps = 24/239 (10%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYE--RDQVMLEQYDKRVQKLESELESVKEFKEKYQS 505
ME + ++++ A L+ + Q + +DQ+ EQY + K + V+E KE+ +
Sbjct: 835 MEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQ-----VRELKEECEE 889
Query: 506 LAKLYSQLRQEHLNILKKMKKTQDDL-AEAESEVKKLKSSALSNVGIRNNNKGESEREEA 564
KL +L+Q+ ++++ +D L A+ E + K S L+ I + E+E+
Sbjct: 890 KTKLGKELQQKK----QELQDERDSLAAQLEITLTKADSEQLAR-SIAEEQYSDLEKEK- 943
Query: 565 KDRSGMILKSL-VESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLL 623
I+K L ++ + + + D + + + +N + D+ + N E + L
Sbjct: 944 ------IMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLK 997
Query: 624 RCPQEMQTIAEDFLRCLSSAKQTD-SVINANIAFQEKLKRLGEI--RQYSYRYGDSDEV 679
+++ + ++ + + Q + ++ + + +L EI R+ + G+ +V
Sbjct: 998 DVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDV 1056
>Hs20485874 [S] KOG4725 Uncharacterized conserved protein
Length = 560
Score = 34.3 bits (77), Expect = 0.64
Identities = 28/128 (21%), Positives = 56/128 (42%), Gaps = 12/128 (9%)
Query: 481 QYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESE--- 537
QY + LES ++ + E +SL + Q+ + L++ KKT +++ +A+ E
Sbjct: 70 QYQELAVALESSSVTISQLNENIESLKQQKKQVEHQ----LEEAKKTNNEIHKAQMERLE 125
Query: 538 ---VKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSD 594
+ L+ + L EE+KD +G + SL I+ L+ + ++
Sbjct: 126 TINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSL--QRIQELERALCAVSTQQ 183
Query: 595 LATDLSNA 602
D S++
Sbjct: 184 QEEDRSSS 191
>Hs17978507 [Z] KOG0161 Myosin class II heavy chain
Length = 1581
Score = 34.3 bits (77), Expect = 0.64
Identities = 58/248 (23%), Positives = 103/248 (41%), Gaps = 34/248 (13%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQ---- 504
+K + QQ L+ + + E Q L+Q K+ Q+L +EL+ K E Q
Sbjct: 937 DKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNH 996
Query: 505 -----------SLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRN 553
L++ + + ++E L K ++ LAEA S ++L+ + G
Sbjct: 997 ELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGF-- 1054
Query: 554 NNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLD--VSDLATDLSNAFIDGDINTI 611
K S E +D S +S E+S+ ++ + L+ V D +L D TI
Sbjct: 1055 TQKVVSLEAELQDISSQ--ESKDEASLAKVKKQLRDLEAKVKDQEEEL-----DEQAGTI 1107
Query: 612 VNILPEFVSLLLRCPQEMQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKRLGEIRQYSY 671
+ LR EM+ + + + + S + + V A + Q+KLK++ E+ Q
Sbjct: 1108 QML----EQAKLRLEMEMERMRQTHSKEMES--RDEEVEEARQSCQKKLKQM-EV-QLEE 1159
Query: 672 RYGDSDEV 679
Y D +V
Sbjct: 1160 EYEDKQKV 1167
>Hs14720884 [R] KOG0504 FOG: Ankyrin repeat
Length = 823
Score = 34.3 bits (77), Expect = 0.64
Identities = 26/137 (18%), Positives = 72/137 (51%), Gaps = 11/137 (8%)
Query: 452 ALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQK-LESELESVKEFKEKYQSLAKLY 510
A+++Q+ +++ND + +N+Y +D ++++ + ++K ++ E + E +YQ +
Sbjct: 522 AILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQ---QEL 578
Query: 511 SQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESER------EEA 564
+ L+ E+ + ++ K ++ E++++ +S + +G +++ ++ER E
Sbjct: 579 NDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAIG-KHSESVKTERNVKLALERT 637
Query: 565 KDRSGMILKSLVESSIK 581
+D S + S S +K
Sbjct: 638 QDVSVQVEMSSAISKVK 654
>CE27133 [Z] KOG0161 Myosin class II heavy chain
Length = 2003
Score = 34.3 bits (77), Expect = 0.64
Identities = 37/192 (19%), Positives = 90/192 (46%), Gaps = 25/192 (13%)
Query: 474 RDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLR----QEHLNILKKMKKTQD 529
+++ ++ +K + + ELES K+ E+ L+SQL+ +E+ ++ K++++T
Sbjct: 1139 KEKAARQKAEKARRDMAEELESYKQELEESNDKTVLHSQLKAKRDEEYAHLQKQLEET-- 1196
Query: 530 DLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIAS 589
+ +E V+++K+ + N + +R++ S KS ES ++ + +++
Sbjct: 1197 -VKSSEEVVEEMKAQNQKKIEELNETIDQLKRQKI---SADKAKSSAESDNENFRAELSN 1252
Query: 590 LDVSDL-------ATDLSNAFIDGDINTIVNILPEFVSLLLRCPQEMQTIAEDFLRCLSS 642
+ + L A + S D + + + L + ++ L + E+++I
Sbjct: 1253 IASARLEAEKKRKAAETSLMEKDHKMREMQSNLDDLMAKLSKMNNELESI--------QK 1304
Query: 643 AKQTDSVINANI 654
AK D +N+N+
Sbjct: 1305 AKSADETLNSNL 1316
Score = 32.7 bits (73), Expect = 1.9
Identities = 31/142 (21%), Positives = 62/142 (42%), Gaps = 17/142 (11%)
Query: 456 QKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELE-SVKEFKEKYQSLAKLYSQLR 514
+K ASL + E D+ + ++++LE +L +V+ + + K+ +++
Sbjct: 1318 KKNASLDMQLSELTEASEEDRRTRATLNNKIRQLEEDLAVAVEARDDALDAQEKIEKEVK 1377
Query: 515 QEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESER----EEAKDRSGM 570
+ + + KK ++ E E++K K LS E ER E+A+D++
Sbjct: 1378 EVKSLLAEARKKLDEENREVMEELRKKKEKELS---------AEKERADMAEQARDKAER 1428
Query: 571 ILKSLV---ESSIKSLQDPIAS 589
K + E K L D +A+
Sbjct: 1429 AKKKAIQEAEDVQKELTDVVAA 1450
>CE08332 [L] KOG0250 DNA repair protein RAD18 (SMC family protein)
Length = 1137
Score = 34.3 bits (77), Expect = 0.64
Identities = 30/143 (20%), Positives = 69/143 (47%), Gaps = 13/143 (9%)
Query: 473 ERDQVMLEQYDK-----RVQKLESELESVKEFKEKYQSLAK----LYSQLRQEHLNILKK 523
E+D+ +L Y RV+ ++ + K+ +E ++ L K Y + R E + KK
Sbjct: 266 EKDRNLLASYRWKFLFCRVRDYDNNIMLNKKKQEVHKKLHKEVKDAYYKNRTERSEVQKK 325
Query: 524 MKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSG----MILKSLVESS 579
+++ +D++ + E+K+ ++ + I N+ K E + E++ R M+++ + +
Sbjct: 326 LQELRDEVEVQDEEIKESRADVDNLRKIVNDLKHEIKMSESQMRRKKVEIMLIRKEIAKA 385
Query: 580 IKSLQDPIASLDVSDLATDLSNA 602
K L++ + +L L+ A
Sbjct: 386 QKQLREALGKFGHEELTKKLAEA 408
Score = 31.6 bits (70), Expect = 4.2
Identities = 42/222 (18%), Positives = 89/222 (39%), Gaps = 12/222 (5%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
EK ++++++ +Q+ + +++ + +K +L+ E++ +Q +
Sbjct: 767 EKLSILEEEAYCIQDKLDELDEKFQPAIKTKNESEKNYVELQQEVKGYAAQTLSFQKQLR 826
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
+ + N L K+K +D+L E+ +K + AL N+ + E R EA
Sbjct: 827 KLDEDGEAGKNRLDKLKSNEDELYHDEARLKSERDEAL-NIVEKEKVTIERPRREADPPD 885
Query: 569 GMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTI---VNILPEFVSLLLRC 625
S ++ K ++ A +S A + + G + + L E +L
Sbjct: 886 LSEFPSTKDARKKIIEMHKA---ISRDAAECGDTVTIGSVKEFKENLKKLRESCRMLEEV 942
Query: 626 PQEMQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKRLGEIR 667
+EMQT+ L+ + K+ + +K K L IR
Sbjct: 943 VEEMQTVHNGRLKAYPTLKK-----YTELKVTDKFKELLAIR 979
>CE00373 [O] KOG2177 Predicted E3 ubiquitin ligase
Length = 851
Score = 34.3 bits (77), Expect = 0.64
Identities = 24/101 (23%), Positives = 41/101 (39%), Gaps = 8/101 (7%)
Query: 453 LIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK---- 508
+IQ + +L DI N + Q+ L DKR+Q + +L EF + S A
Sbjct: 321 VIQDQKKTLAKDI---DNAFAAKQIQLTMVDKRIQSMADKLSQTIEFSRRLMSFASPAEV 377
Query: 509 -LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSN 548
++ QL L + + E++ L ++ L N
Sbjct: 378 MVFKQLLDTRLQLFLGFNPDTSGVLMTPCEIEYLGAAGLFN 418
>At3g20760 [S] KOG2866 Uncharacterized conserved protein
Length = 373
Score = 34.3 bits (77), Expect = 0.64
Identities = 30/109 (27%), Positives = 52/109 (47%), Gaps = 12/109 (11%)
Query: 513 LRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMI- 571
+R ++L + K+K +DDL + +S K +++ N + K RE+ D ++
Sbjct: 65 IRSQYLALTHKIKDAKDDLTKIDSN----KFNSIINEVENLHQKVRKPREQIADAEALLD 120
Query: 572 LKSLVESSIKSLQDPIASLDVSDLATDLSNAF------IDGDINTIVNI 614
L + V SS+KS Q + ++ L N F ID D NT V++
Sbjct: 121 LTNSVVSSVKS-QSAHGGVSPAEFVNALINGFGKTSLRIDADENTQVSM 168
>At1g73960 [K] KOG1932 TATA binding protein associated factor
Length = 1273
Score = 34.3 bits (77), Expect = 0.64
Identities = 38/123 (30%), Positives = 59/123 (47%), Gaps = 24/123 (19%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESV-KEFKEKYQSL 506
ME EA QQK ASLQ + + + ++D+ E+ KR + E + + KE K K + +
Sbjct: 1152 MENEA--QQKYASLQTLSIGKEKEKKKDKEKKEKKRKREDPVYLEKKRLKKEKKRKEKEM 1209
Query: 507 AKLYS--------------QLRQEHLN----ILKKMKKTQDDLAEAESEVK---KLKSSA 545
AKL S ++++E + ++K KT+ AEA K KLKS A
Sbjct: 1210 AKLVSSTTDPAKKKIESVAEVKEEEPSDGAMLIKVEPKTEPSTAEARPLPKFRIKLKSKA 1269
Query: 546 LSN 548
+N
Sbjct: 1270 FNN 1272
>SPCC364.04c [K] KOG0963 Transcription factor/CCAAT displacement protein CDP1
Length = 633
Score = 33.9 bits (76), Expect = 0.84
Identities = 25/93 (26%), Positives = 44/93 (46%), Gaps = 6/93 (6%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKL 509
K+ +QK+ S Q+D+ + + Q L+ D +KL +ELES+KE K
Sbjct: 261 KQNTKEQKSGSSQDDLSNQQKQ------QLDFMDSLNKKLSTELESIKEASRKEMETHCA 314
Query: 510 YSQLRQEHLNILKKMKKTQDDLAEAESEVKKLK 542
Q + + +K+K+ LA S+ ++K
Sbjct: 315 TIQTLENEVKEARKVKEESLTLANKFSDYDEIK 347
>SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1837
Score = 33.9 bits (76), Expect = 0.84
Identities = 34/160 (21%), Positives = 69/160 (42%), Gaps = 10/160 (6%)
Query: 450 KEALIQQKTASLQNDIMSFKNQY----ERDQVMLEQYDKRVQKLESELESVKEFKEKYQS 505
KE ++ +SLQ + + + Q + LE+ + + L S E E Y+S
Sbjct: 689 KEKKFEEAISSLQLEKSNIQLQLTSLTSERSLALEKLNDLEKSLVLSERSKDELDESYKS 748
Query: 506 LAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAK 565
L + + + E N+ ++ L ++ V LKS L +++ K + E+K
Sbjct: 749 LQEQLASKKIEVQNVSSQLSICNSQLEQSNHIVDNLKSENLLLTSVKDKLKADLSNLESK 808
Query: 566 ----DRSGMILKSLVESSIKSLQDPIASLD--VSDLATDL 599
+ +K+ +ESS + + S++ + +L+ DL
Sbjct: 809 LSSLQQDNFHMKAQIESSNQEYTATVDSMNSRILELSNDL 848
Score = 32.0 bits (71), Expect = 3.2
Identities = 31/137 (22%), Positives = 56/137 (40%), Gaps = 6/137 (4%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQS-LAKLYSQL 513
Q LQ++I K + + Q + + +L+ L+ ++E +E QS L
Sbjct: 877 QTLVLQLQSNITELKQDITLQRTVRNQLEIQTTELKERLKFMEERQENLQSKLIAANKDT 936
Query: 514 RQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILK 573
Q N+ + + E E +KL+ + L I+ + E + + K
Sbjct: 937 TQNPDNV-----EVEAISIELERTKEKLRMAELEKSNIQQKYLASEKTLEMMNETHEQFK 991
Query: 574 SLVESSIKSLQDPIASL 590
LVES I + ++ I SL
Sbjct: 992 HLVESEISTREEKITSL 1008
>Hs8922940 [Z] KOG1850 Myosin-like coiled-coil protein
Length = 528
Score = 33.9 bits (76), Expect = 0.84
Identities = 42/180 (23%), Positives = 74/180 (40%), Gaps = 28/180 (15%)
Query: 457 KTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQE 516
K LQ ++ K Q + Q++ E +K ++ E L+ E + KY+ + + QL+Q+
Sbjct: 295 KRKELQQQLVDAKLQ-QTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQ 353
Query: 517 HLNILKKMKKTQDDLA-----------EAESEVKKLKSSALSNVGIR----NNNKGESER 561
+ K ++ Q +A E E KK+K + R NNNK +
Sbjct: 354 LSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQM 413
Query: 562 EEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSL 621
E K++ + K+LQ + L+ A ++N V +L E VS+
Sbjct: 414 AEE--------KTVRDKEYKALQIKLERLEKLCRALQTER----NELNEKVEVLKEQVSI 461
Score = 32.7 bits (73), Expect = 1.9
Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 4/68 (5%)
Query: 468 FKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKT 527
F+ + Q LEQ+D KL E E EK + L + Y+ LR+EH++ + K K+
Sbjct: 244 FQITLDEIQAQLEQHDIHNAKLRQENI---ELGEKLKKLIEQYA-LREEHIDKVFKRKEL 299
Query: 528 QDDLAEAE 535
Q L +A+
Sbjct: 300 QQQLVDAK 307
>Hs14772793 [Z] KOG0161 Myosin class II heavy chain
Length = 1220
Score = 33.9 bits (76), Expect = 0.84
Identities = 40/183 (21%), Positives = 81/183 (43%), Gaps = 18/183 (9%)
Query: 481 QYDKRVQKLESELESVK----EFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAES 536
Q ++ + L +EL ++ + K Q L + + + QE ++ +++ QD+LA+AE
Sbjct: 549 QAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEE 608
Query: 537 EVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASL--DVSD 594
L S V + K SER E ++ + + + + + L+D L D+ D
Sbjct: 609 RCHLL---IKSKVQLEGKVKELSERLEDEEE----VNADLAARRRKLEDECTELKKDIDD 661
Query: 595 LATDLSNAFIDGDI--NTIVNILPEFVSL---LLRCPQEMQTIAEDFLRCLSSAKQTDSV 649
L L+ A + N + N+ E +L + R +E + + E + L + +
Sbjct: 662 LKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDR 721
Query: 650 INA 652
++A
Sbjct: 722 VSA 724
>Hs14149971 [R] KOG0504 FOG: Ankyrin repeat
Length = 823
Score = 33.9 bits (76), Expect = 0.84
Identities = 29/136 (21%), Positives = 66/136 (48%), Gaps = 7/136 (5%)
Query: 452 ALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQ---KLESEL--ESVKEFKEKYQSL 506
A+++Q+ +++ND + +N+Y +D ++++ + ++ KL E+ E+ ++++ L
Sbjct: 522 AILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDL 581
Query: 507 AKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKD 566
++L E L + K+ + D+ +S + S +V N K ER +D
Sbjct: 582 KAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALER--TRD 639
Query: 567 RSGMILKSLVESSIKS 582
S + S S +K+
Sbjct: 640 VSVQVEMSSAISKVKA 655
>Hs11321579 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 33.9 bits (76), Expect = 0.84
Identities = 29/136 (21%), Positives = 59/136 (43%), Gaps = 10/136 (7%)
Query: 452 ALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYS 511
A + +K + + +K + + Q LE K + L +EL ++ Y+ +
Sbjct: 1444 ATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRN---AYEEVVDQLE 1500
Query: 512 QLRQEHLNILKKMKKTQDDLAEA------ESEVKKLKSSALSNVGIR-NNNKGESEREEA 564
LR+E+ N+ +++ + +AE + KKL S++ + +G E EE+
Sbjct: 1501 TLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEES 1560
Query: 565 KDRSGMILKSLVESSI 580
K + S V+S +
Sbjct: 1561 KILRVQLELSQVKSEL 1576
Score = 33.5 bits (75), Expect = 1.1
Identities = 34/162 (20%), Positives = 72/162 (43%), Gaps = 25/162 (15%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLR 514
Q+K LQ I + + E + + + +K+ L ELE + E E+ ++
Sbjct: 1109 QKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMN 1168
Query: 515 QEHLNILKKMKKTQDDLAEA-------ESEVKKLKSSALSNVGIRNNN------KGESER 561
++ +KM++ DL EA + ++K ++ +++ +G + +N K E E+
Sbjct: 1169 KKREAEFQKMRR---DLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEK 1225
Query: 562 EEAK----DRSGMI-----LKSLVESSIKSLQDPIASLDVSD 594
E K D + I KS +E + ++++D + + D
Sbjct: 1226 SELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKD 1267
Score = 32.0 bits (71), Expect = 3.2
Identities = 50/234 (21%), Positives = 91/234 (38%), Gaps = 40/234 (17%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
EKE+LI Q T S Q + +Q ++ +++E E ++ QS
Sbjct: 1297 EKESLISQLTKS--------------KQALTQQLEELKRQMEEETKAKNAMAHALQSSRH 1342
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
LR+++ + + Q L++A SEV + K+ ++ R E EEAK +
Sbjct: 1343 DCDLLREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRT-----EELEEAKKKL 1397
Query: 569 GMILKSLVESSIKSLQDPIASL---------DVSDLATDLSN-----AFIDGDINTIVNI 614
L+ E ++ ASL +V DL DL A +D +
Sbjct: 1398 AQRLQE-AEEKTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKV 1456
Query: 615 LPEFVSLLLRCPQEMQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKRLGEIRQ 668
L E+ L E++ ++ S + + A++E + +L +R+
Sbjct: 1457 LAEWKQKLDESQAELEAAQKE------SRSLSTELFKMRNAYEEVVDQLETLRR 1504
>CE23997 [Z] KOG3595 Dyneins heavy chain
Length = 4568
Score = 33.9 bits (76), Expect = 0.84
Identities = 20/89 (22%), Positives = 46/89 (51%), Gaps = 3/89 (3%)
Query: 457 KTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQE 516
K L+N++ + + + + D R+ +LE ES+ ++KE+Y L ++Q+
Sbjct: 3351 KVEPLRNELKRLEQEAAKKTQEGKVVDVRITELE---ESIGKYKEEYAQLIGQAENIKQD 3407
Query: 517 HLNILKKMKKTQDDLAEAESEVKKLKSSA 545
L++ +K+ ++ + L+ SE + S +
Sbjct: 3408 LLSVQEKVNRSTELLSSLRSERDRWSSGS 3436
>CE20196 [Z] KOG0161 Myosin class II heavy chain
Length = 1413
Score = 33.9 bits (76), Expect = 0.84
Identities = 33/128 (25%), Positives = 63/128 (48%), Gaps = 11/128 (8%)
Query: 469 KNQYERDQVMLEQYDKRVQKLESELESVKEFK---EKYQSLAKLYSQLRQEHLNILKKMK 525
K++ + Q LE+ +K Q E LE +EF+ E+ + ++++ L +++ KK+
Sbjct: 818 KSEKVKVQKELEEVEK--QGREKLLEKEREFRKTMEEMEQNEEIFNVLERKYNEQHKKVM 875
Query: 526 KTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKD-RSGMILKSLVESS--IKS 582
K D L E E ++++L + + N N+ E + +D + K ++E S I
Sbjct: 876 KMNDVLREYERKIEQLN---MEKTDLENENQKLRETQNRQDSHYSNLEKEVMEKSSLIDE 932
Query: 583 LQDPIASL 590
LQ+ I L
Sbjct: 933 LQNQIQKL 940
Score = 30.4 bits (67), Expect = 9.3
Identities = 27/127 (21%), Positives = 55/127 (43%), Gaps = 2/127 (1%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKY-QSLAKLYSQ 512
+Q+ + L I F N ++ + ++ +KL EL + KE +K + + +L +
Sbjct: 975 MQKLISELNEKIARFDNIALNERNSTRKIEREKEKLNEELTTAKEIIQKQAKKIDELKEE 1034
Query: 513 LRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAK-DRSGMI 571
R+ + +K +D A VK+LK S + + +R+ +K +
Sbjct: 1035 CRKRKNEASRLERKLEDKEAMMADCVKELKDSHKERLKEMEQKVEDVKRKNSKLENENST 1094
Query: 572 LKSLVES 578
KS +E+
Sbjct: 1095 QKSQIET 1101
>CE15865 [R] KOG2501 Thioredoxin nucleoredoxin and related proteins
Length = 777
Score = 33.9 bits (76), Expect = 0.84
Identities = 27/129 (20%), Positives = 63/129 (47%), Gaps = 14/129 (10%)
Query: 457 KTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLES----ELESVKEFKEKYQSLAKLYSQ 512
K+ SL++ I F +++ V + ++ ++ +LE +LE + +++ + ++ S+
Sbjct: 460 KSLSLRSSISEFSSEHSHSTVTVIEHSEKTYELEQNVRIDLEETLKLEKRIEEVSIEESK 519
Query: 513 LRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMIL 572
+QE L LK+ ++ + + E E + +K+ + + + E EEA+ ++ L
Sbjct: 520 KKQEKLE-LKQREEEEARIKEEEEKQRKI---------LEEEARKKQEEEEARLKAEEEL 569
Query: 573 KSLVESSIK 581
K E K
Sbjct: 570 KIYEEEKRK 578
>CE10260 [U] KOG1655 Protein involved in vacuolar protein sorting
Length = 217
Score = 33.9 bits (76), Expect = 0.84
Identities = 22/123 (17%), Positives = 58/123 (46%), Gaps = 3/123 (2%)
Query: 480 EQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVK 539
+ DK++QKL+ +L +++ K + + ++Q+ L +LK+ + ++ + + +
Sbjct: 28 DSIDKKIQKLDQDLMKLRDQMSKMRE-GPSKNLIKQKALRVLKQKRMYENQKGQLDQQAF 86
Query: 540 KLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDL 599
+ S + G+++N + ++ K + I+ LQD + D+ D+ ++
Sbjct: 87 NMDQSNFAIQGMKDNQVTVAAMKDGLKTMQKEYKKMNIDQIEDLQDQME--DMLDMNNEI 144
Query: 600 SNA 602
A
Sbjct: 145 QEA 147
>At2g22610 [Z] KOG0239 Kinesin (KAR3 subfamily)
Length = 1068
Score = 33.9 bits (76), Expect = 0.84
Identities = 35/161 (21%), Positives = 81/161 (49%), Gaps = 14/161 (8%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESEL-ESVKE----FKEKYQSLAK 508
+Q+K LQN + S NQ E+ L++ K ++ S L + VKE +E++QS +
Sbjct: 783 LQEKNKDLQNQLDSVHNQSEKQYAQLQERLKSRDEICSNLQQKVKELECKLRERHQSDSA 842
Query: 509 LYSQLRQEHLNILKKMKKT----QDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEA 564
+Q ++ N LK+ + + Q + + E+++K+ + ++L V + + E + ++
Sbjct: 843 ANNQKVKDLENNLKESEGSSLVWQQKVKDYENKLKESEGNSL--VWQQKIKELEIKHKDE 900
Query: 565 KDRSGMILKSLV---ESSIKSLQDPIASLDVSDLATDLSNA 602
+ + ++L+ + E +K + I + + +++NA
Sbjct: 901 QSQEAVLLRQKIKELEMRLKEQEKHIQEMATTREFPEVANA 941
>7299993 [Z] KOG1003 Actin filament-coating protein tropomyosin
Length = 284
Score = 33.9 bits (76), Expect = 0.84
Identities = 38/166 (22%), Positives = 74/166 (43%), Gaps = 25/166 (15%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDK--------------RVQKLESELESVKEF 499
+++K ++ D+++ K Q E+ LE+ +K +VQ++E +LE +E
Sbjct: 46 LEKKFVQVEIDLVTAKEQLEKANTELEEKEKLLTATESEVATQNRKVQQIEEDLEKSEER 105
Query: 500 KEKYQSLAKLYSQLRQEHLNILKKMK-KTQDDLAEAESEVKKLKSSAL--------SNVG 550
Q +Q E+ + K ++ ++Q D + +LK + + S+
Sbjct: 106 STTAQQKLLEATQSADENNRMCKVLENRSQQDEERMDQLTNQLKEARMLAEDADTKSDEV 165
Query: 551 IRNNNKGESEREEAKD--RSGMILKSLVESSIKSLQDPIASLDVSD 594
R E E E A+D RSG +E +K + + + SL+VS+
Sbjct: 166 SRKLAFVEDELEVAEDRVRSGESKIMELEEELKVVGNSLKSLEVSE 211
Score = 31.2 bits (69), Expect = 5.4
Identities = 22/102 (21%), Positives = 51/102 (49%), Gaps = 9/102 (8%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQY-----DKRVQKLESELE----SVKEFK 500
KEA + + A ++D +S K + D++ + + + ++ +LE EL+ S+K +
Sbjct: 149 KEARMLAEDADTKSDEVSRKLAFVEDELEVAEDRVRSGESKIMELEEELKVVGNSLKSLE 208
Query: 501 EKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLK 542
+ + + ++E + K+K+ + AE +VK+L+
Sbjct: 209 VSEEKANQRVEEFKREMKTLSIKLKEAEQRAEHAEKQVKRLQ 250
>7295428 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation
Length = 1031
Score = 33.9 bits (76), Expect = 0.84
Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 14/98 (14%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKL 509
K+AL QK L D+ ++ +RD+V L +K KL SE+E ++ Q L KL
Sbjct: 666 KKALNDQKEMKLLLDMYKGVSKDQRDKVQLMATEK---KLRSEIEELR------QQLKKL 716
Query: 510 YSQLRQEHLNI-----LKKMKKTQDDLAEAESEVKKLK 542
R+E + L+K+K+ ++ E + ++ K
Sbjct: 717 QESKREERKKLADEEALRKIKQLEEQKYELQKQMANHK 754
>7293607 [DK] KOG4466 Component of histone deacetylase complex (breast
carcinoma metastasis suppressor 1 protein in human)
Length = 327
Score = 33.9 bits (76), Expect = 0.84
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 14/99 (14%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKL 509
KE + Q K +LQ K E Q++ +Y KRV+KL+S+L+ + E Y K
Sbjct: 61 KEQMYQHKLFNLQ------KQMEELGQLVHPEYLKRVKKLDSQLKERRRMNEVY----KE 110
Query: 510 YSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSN 548
Y + E +L+KM + E + ++ LK + +S+
Sbjct: 111 YMRECVERDYVLEKMAAQK----EYDEKMMDLKDNLISD 145
>7291239 [U] KOG0993 Rab5 GTPase effector Rabaptin-5
Length = 562
Score = 33.9 bits (76), Expect = 0.84
Identities = 25/117 (21%), Positives = 53/117 (44%), Gaps = 13/117 (11%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E +A Q K + LQN++ +N++ +R + E ++ E + Q +
Sbjct: 20 EDDATSQHKLSHLQNEMRKMQNEFN---------TQRAKMRELYIQKEAEVSQSQQERRQ 70
Query: 509 LYSQLRQEHLNILKKMKKTQDDL----AEAESEVKKLKSSALSNVGIRNNNKGESER 561
L ++L + +++ K+Q++L +A+ E+ L+ + + KGE ER
Sbjct: 71 LQAELDELKTHLMVADLKSQNELQLRDLKAQEEISSLQQLVQDTIEETAHYKGEVER 127
>7290766 [K] KOG4673 Transcription factor TMF TATA element modulatory factor
Length = 933
Score = 33.9 bits (76), Expect = 0.84
Identities = 23/96 (23%), Positives = 50/96 (51%), Gaps = 8/96 (8%)
Query: 451 EALIQQKTASLQNDIMSFKNQYERDQVMLEQ--YDKRVQKLESELESVKEFKEKYQSLAK 508
+AL++Q+ L + Q+E ++ E+ D + L ELE++KE ++ Y+ + K
Sbjct: 821 QALLKQRDGELTH------LQWEVSRLQAERSVLDAEISNLTIELETMKEKQQMYEVMEK 874
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSS 544
Y L+ + +L+ + + E E ++ +LK++
Sbjct: 875 GYEDLQHRYDALLQMYGEKVERTEELELDLTELKAA 910
>Hs7662062_2 [U] KOG0864 Ran-binding protein RANBP1 and related RanBD domain
proteins
Length = 321
Score = 33.9 bits (76), Expect = 0.84
Identities = 31/146 (21%), Positives = 69/146 (47%), Gaps = 17/146 (11%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQY--------ERDQVMLEQYDKRVQKLESELESVKEF 499
+ KEA +++K S+Q++ M K+++ +++V+ + +V+ L+ E E
Sbjct: 38 VSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVET 97
Query: 500 KEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAES--EVKKLKSSALSNVGIRNNNKG 557
+ Q L+K+ +QL Q LK T+ ++ +S +++ +++ L + + +
Sbjct: 98 LQ--QQLSKMEAQLFQ-----LKNEPTTRSPVSSQQSLKNLRERRNTDLPLLDMHTVTRE 150
Query: 558 ESEREEAKDRSGMILKSLVESSIKSL 583
E E E D + S S++ L
Sbjct: 151 EGEGMETTDTESVSSASTYTQSLEQL 176
>7292701_2 [S] KOG4415 Uncharacterized conserved protein
Length = 1643
Score = 33.9 bits (76), Expect = 0.84
Identities = 31/134 (23%), Positives = 63/134 (46%), Gaps = 16/134 (11%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
EKE L+++K + K + ER + + E+ +R +KL+ E E + KE+ + L +
Sbjct: 905 EKEELLKKKEKEEKEREEKLKEK-ERQEKLKEK--EREEKLKRETEERQREKEREEKLKE 961
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
+ + L K+K+ ++ L E E E+K K E ++ + K++S
Sbjct: 962 KERAEKLKDLEKEVKLKEKEEQLKEKEKELKL-------------KEKKEKDKVKEKEKS 1008
Query: 569 GMILKSLVESSIKS 582
K L+ +++ +
Sbjct: 1009 LESEKLLISATVSN 1022
Score = 33.5 bits (75), Expect = 1.1
Identities = 20/100 (20%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 469 KNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLA-KLYSQLRQEHLNILKKMKKT 527
K + + ++ L++ ++ + E E E + KE+ +SL + +L++E + ++ +K
Sbjct: 723 KEKAKEKELKLKEKEREAKLQEKEKEEKLKLKEREESLRMEREEKLKEEKIKEKEREEKL 782
Query: 528 QDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDR 567
+++ + + +KLK L K + E+AK++
Sbjct: 783 KEEKIKEKQREEKLKEEKLKEKEREERMKEKEREEKAKEK 822
Score = 30.8 bits (68), Expect = 7.1
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 9/109 (8%)
Query: 480 EQYDKRVQKLESELESVKEFKEKYQSLA--KLYSQLRQEHLNILKKMKKTQDDLAEAESE 537
E+ +K +KL E KE +EK + K+ + R+E + ++++K ++ E E +
Sbjct: 837 EREEKLKEKLREEKIKEKEKEEKLRKEREEKMREKEREEKIKEKERVEKIKEK--EREEK 894
Query: 538 VKKLKSSALSNVG--IRNNNKGESEREE---AKDRSGMILKSLVESSIK 581
+KK K L ++ K E EREE K+R + + E +K
Sbjct: 895 LKKEKEEKLKEKEELLKKKEKEEKEREEKLKEKERQEKLKEKEREEKLK 943
>YJL074c [D] KOG0964 Structural maintenance of chromosome protein 3 (sister
chromatid cohesion complex Cohesin subunit SMC3)
Length = 1230
Score = 33.5 bits (75), Expect = 1.1
Identities = 45/197 (22%), Positives = 93/197 (46%), Gaps = 29/197 (14%)
Query: 452 ALIQQKTASL---QNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQ---- 504
A +QQK L + + FK++ ERD + +++L+S ++++ E + + Q
Sbjct: 374 ASLQQKQRDLILKKGEYARFKSKDERDTWI----HSEIEELKSSIQNLNELESQLQMDRT 429
Query: 505 SLAKLYSQLRQEHLNILKKMK--KTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESERE 562
SL K YS + +E ++ + T+ L + +SE+ LK ++ R E R+
Sbjct: 430 SLRKQYSAIDEEIEELIDSINGPDTKGQLEDFDSELIHLKQKLSESLDTRK----ELWRK 485
Query: 563 EAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFID-GDINTIVNILPEFV-- 619
E K L++++E+ + + +++ ++ L+N I+ +I + I PE V
Sbjct: 486 EQK------LQTVLETLLSDVNQNQRNVN-ETMSRSLANGIINVKEITEKLKISPESVFG 538
Query: 620 --SLLLRCPQEMQTIAE 634
L++ + +T AE
Sbjct: 539 TLGELIKVNDKYKTCAE 555
Score = 30.8 bits (68), Expect = 7.1
Identities = 17/60 (28%), Positives = 31/60 (51%)
Query: 483 DKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLK 542
DK +L ++ K F+ K ++ K + Q+ + I K+M + L+E E E K+L+
Sbjct: 159 DKERLQLLEDVVGAKSFEVKLKASLKKMEETEQKKIQINKEMGELNSKLSEMEQERKELE 218
>Hs9055284 [Z] KOG0160 Myosin class V heavy chain
Length = 1742
Score = 33.5 bits (75), Expect = 1.1
Identities = 24/107 (22%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Query: 484 KRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKS 543
+++QKLE+ELE + Y+ K Y +E L L+K ++ + + + ++K +
Sbjct: 924 EKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQK-HNSELETQKEQIQLKLQEK 982
Query: 544 SALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASL 590
+ + N K + + ++R M+L+ E + + I SL
Sbjct: 983 TEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSL 1029
Score = 31.2 bits (69), Expect = 5.4
Identities = 44/236 (18%), Positives = 93/236 (38%), Gaps = 32/236 (13%)
Query: 451 EALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLY 510
E L Q S + + K ++++ ++ +K + K++ E+ K+++++ +++
Sbjct: 1244 EELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVK 1303
Query: 511 SQLRQEHLNILKKMKKTQDDLAEAESEVKKLK------SSALSNVGIRNNNKGESE---- 560
RQE + + + +++L + +KKL+ S + +++ G E
Sbjct: 1304 CNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGM 1363
Query: 561 -----REEAKDRSGMIL----KSLVESSIKSLQDPIA--------SLDVSDLATDLSNAF 603
+EAK +IL + +V + I L I SL+ +++ L N+
Sbjct: 1364 LQYKREDEAKLIQNLILDLKPRGVVVNMIPGLPAHILFMCVRYADSLNDANMLKSLMNST 1423
Query: 604 IDGDINTIVNILPEFVSLLLRCPQEMQTIAEDFLRCLSSAKQTDSVINANIAFQEK 659
I+G + L +F L FL CL + + N Q K
Sbjct: 1424 INGIKQVVKEHLEDFEMLSFWLSNTCH-----FLNCLKQYSGEEEFMKHNSPQQNK 1474
>Hs4506467 [R] KOG3529 Radixin moesin and related proteins of the ERM family
Length = 583
Score = 33.5 bits (75), Expect = 1.1
Identities = 27/123 (21%), Positives = 56/123 (44%), Gaps = 21/123 (17%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
+QQ A + + K+Q + ++ LE K+ + E E E ++ KE+
Sbjct: 302 VQQMKAQAREE----KHQKQLERAQLENEKKKREIAEKEKERIEREKEE----------- 346
Query: 514 RQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILK 573
+++++K+ ++ +A+ E+++ AL R K E+ER E + R+ K
Sbjct: 347 ------LMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAK 400
Query: 574 SLV 576
S +
Sbjct: 401 SAI 403
>Hs4502443 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein) and related
proteins
Length = 2649
Score = 33.5 bits (75), Expect = 1.1
Identities = 26/93 (27%), Positives = 46/93 (48%), Gaps = 6/93 (6%)
Query: 451 EALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELES-VKEFKEKYQSLAKL 509
E L++ K + +NDI + D V L+Q + R Q+ E+ +KE + + Q +
Sbjct: 1759 EKLMESKVIT-ENDISGIR----LDFVSLQQENSRAQENAKLCETNIKELERQLQQYREQ 1813
Query: 510 YSQLRQEHLNILKKMKKTQDDLAEAESEVKKLK 542
Q + N +K +K +D+L + EV+ LK
Sbjct: 1814 MQQGQHMEANHYQKCQKLEDELIAQKREVENLK 1846
Score = 32.3 bits (72), Expect = 2.4
Identities = 32/140 (22%), Positives = 59/140 (41%), Gaps = 18/140 (12%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLA 507
+EK+ IQQ+ +L+ FK+Q L + K Q + +++ ++E K Q+L
Sbjct: 1602 LEKQT-IQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLV 1660
Query: 508 KLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDR 567
+ Q + I++ KK EV+ L + N +K E R E K +
Sbjct: 1661 SEFKQKCDQQNIIIQNTKK----------EVRNLNAEL-------NASKEEKRRGEQKVQ 1703
Query: 568 SGMILKSLVESSIKSLQDPI 587
+ + +K +QD +
Sbjct: 1704 LQQAQVQELNNRLKKVQDEL 1723
Score = 30.8 bits (68), Expect = 7.1
Identities = 27/110 (24%), Positives = 53/110 (47%), Gaps = 7/110 (6%)
Query: 453 LIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVK----EFKEKYQSLAK 508
+++QK L K +R Q E Q ++ E++K FK++ +S +
Sbjct: 1571 MLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNE 1630
Query: 509 -LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSA-LSNVGIRNNNK 556
L+ Q + E + +K+K ++DLA++++ V + K N+ I+N K
Sbjct: 1631 HLHKQTKTEQ-DFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKK 1679
>Hs16507950 [Z] KOG2685 Cystoskeletal protein Tektin
Length = 430
Score = 33.5 bits (75), Expect = 1.1
Identities = 18/69 (26%), Positives = 42/69 (60%), Gaps = 6/69 (8%)
Query: 486 VQKLESELESVK-----EFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVK- 539
+ + +ELE+ + F+++ + + K+YS+L+ + N L+++ + Q+D+ E +++
Sbjct: 247 IAETNNELEAQRVATEFAFRKRLREMEKVYSELKWQEKNTLEEIAELQEDIRHLEEDLRT 306
Query: 540 KLKSSALSN 548
KL S LS+
Sbjct: 307 KLLSLKLSH 315
>Hs14735371 [S] KOG4725 Uncharacterized conserved protein
Length = 834
Score = 33.5 bits (75), Expect = 1.1
Identities = 19/91 (20%), Positives = 45/91 (48%), Gaps = 13/91 (14%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
+Q K + LQ +++++ ++ +Q + +V LE EL ++ KE +
Sbjct: 305 VQAKLSELQETSEQAQSKFKSEKQNRKQLELKVTSLEEELTDLRVEKESLEK-------- 356
Query: 514 RQEHLNILKKMKKTQDDLAEAESEVKKLKSS 544
N+ ++ KK+ + ++AE E+ +++ S
Sbjct: 357 -----NLSERKKKSAQERSQAEEEIDEIRKS 382
>Hs13899237 [D] KOG4438 Centromere-associated protein NUF2
Length = 464
Score = 33.5 bits (75), Expect = 1.1
Identities = 24/83 (28%), Positives = 41/83 (48%), Gaps = 4/83 (4%)
Query: 461 LQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNI 520
+++ + KN + E Y V L S V+ +++K Q L S R++ +I
Sbjct: 258 MKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKKIQDL----SDNREKLASI 313
Query: 521 LKKMKKTQDDLAEAESEVKKLKS 543
LK+ +D + ESE+KKLK+
Sbjct: 314 LKESLNLEDQIESDESELKKLKT 336
>Hs11342676 [Z] KOG3565 Cdc42-interacting protein CIP4
Length = 545
Score = 33.5 bits (75), Expect = 1.1
Identities = 26/88 (29%), Positives = 46/88 (51%), Gaps = 9/88 (10%)
Query: 469 KNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSL------AKLYSQLRQEHLNILK 522
+ Q +R Q LE+ + +QK + E++K+ K+ Y+ A L Q+ + NI +
Sbjct: 341 EQQRKRLQQQLEERSRELQKEVDQREALKKMKDVYEKTPQMGDPASLEPQIAETLSNIER 400
Query: 523 ---KMKKTQDDLAEAESEVKKLKSSALS 547
+++K + LAEAES V + +LS
Sbjct: 401 LKLEVQKYEAWLAEAESRVLSNRGDSLS 428
>CE21053 [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 878
Score = 33.5 bits (75), Expect = 1.1
Identities = 24/86 (27%), Positives = 49/86 (56%), Gaps = 6/86 (6%)
Query: 479 LEQYDKRVQKLESELE-SVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESE 537
L Q ++V +LE +L + F+++ Q++ S E+ N+ ++ KT+ LAEA +
Sbjct: 756 LAQLQQQVNELEQQLGFGYQAFEQQSQTMLHYTS----ENANLKDRLAKTEAALAEANYK 811
Query: 538 VKKLKSSALSNVGIRNNNKGESEREE 563
+++L +SN GI ++ +++ EE
Sbjct: 812 IEQLNLKPISN-GIVVEHEPQADSEE 836
>CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1228
Score = 33.5 bits (75), Expect = 1.1
Identities = 21/90 (23%), Positives = 45/90 (49%), Gaps = 4/90 (4%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLE--QYDKRVQKLESELESVKEFKEKYQS 505
+ A ++ Q + K +++ + L+ Q +KR Q LE E ++KE + KY
Sbjct: 1120 LRMRAALEDHDLKSQKKLQILKERHQEAIIELDEMQNEKRKQLLEKERNTMKEHEAKYHE 1179
Query: 506 LAKLYSQLRQEHLNILKKMKKTQDDLAEAE 535
+ +L+ + +L+ +K +D+L++ E
Sbjct: 1180 MRELWQENLIARKTVLE--EKFEDELSKQE 1207
>At3g58430 [DR] KOG1987 Speckle-type POZ protein SPOP and related proteins
with TRAF MATH and BTB/POZ domains
Length = 552
Score = 33.5 bits (75), Expect = 1.1
Identities = 29/110 (26%), Positives = 54/110 (48%), Gaps = 3/110 (2%)
Query: 485 RVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSS 544
+V LE +L+ VKE KEK S + Q ++HL LK+ DDL + + + S
Sbjct: 422 KVDWLEKKLDQVKEKKEKELS-DMVQLQEMEDHLLKLKQSCSDLDDLVVKKKDELSVTRS 480
Query: 545 ALS--NVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDV 592
LS +V + + ++ +++SG+ +E + L+ ++LD+
Sbjct: 481 PLSFDDVDWLEKKLDQVKDKKEREQSGLARLHELEEYLLKLKQKCSNLDL 530
>At1g70460 [T] KOG1187 Serine/threonine protein kinase
Length = 710
Score = 33.5 bits (75), Expect = 1.1
Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 2/64 (3%)
Query: 330 PSPVHEAPPVARPAEVRSLSQPAAPVVPIATGVVMPVVTGYSQPPLQVVPTGAEFWSIPS 389
P P APP + PA+ S PA P +P A P V+ PPL P + P
Sbjct: 30 PPPTDSAPPPSPPAD--SSPPPALPSLPPAVFSPPPTVSSPPPPPLDSSPPPPPDLTPPP 87
Query: 390 TSAP 393
+S P
Sbjct: 88 SSPP 91
>7301970 [V] KOG2392 Serpin
Length = 649
Score = 33.5 bits (75), Expect = 1.1
Identities = 29/122 (23%), Positives = 59/122 (47%), Gaps = 1/122 (0%)
Query: 470 NQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQD 529
++++RD + +K V + E+EL KE K++ + ++L SQ + ++K +K
Sbjct: 220 SKFDRDVDDKQYVEKPVAQAEAELLQ-KEQKQQATTESELESQPEETTTLSVEKQEKPDM 278
Query: 530 DLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIAS 589
E +E ++ K S I+N + E+ +EE K M +L + ++ P+
Sbjct: 279 AAEENPAEKQQNKRSDQEESQIKNLEENETVQEEEKLAKIMAAPALTAGEPEKVRLPLQK 338
Query: 590 LD 591
L+
Sbjct: 339 LE 340
>7296430 [TV] KOG4297 C-type lectin
Length = 800
Score = 33.5 bits (75), Expect = 1.1
Identities = 27/112 (24%), Positives = 54/112 (48%), Gaps = 9/112 (8%)
Query: 462 QNDIMSFKNQYERDQVMLEQYDKRVQKLE---SELESVKEFKEKYQ--SLAKLYSQLRQE 516
Q D K++ E+D++ E+ R + E ++ + ++E K K + + Y Q ++E
Sbjct: 433 QRDEQEQKDREEQDRLKQEEEQARTHQKELKENQEQQLRELKAKQEREKQERDYQQQKRE 492
Query: 517 H-LNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDR 567
H L +LK+ + D A+ E +KL+ L + + + + RE + R
Sbjct: 493 HELELLKQRQAEADRQHAADEEAEKLR---LERIQKQRELEAQQRREREEQR 541
>Hs22045770_1 [R] KOG0504 FOG: Ankyrin repeat
Length = 817
Score = 33.5 bits (75), Expect = 1.1
Identities = 22/98 (22%), Positives = 51/98 (51%), Gaps = 2/98 (2%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKL-ESELESVKEFKEKY-QSL 506
EK +++ L+ ++++ K E+D V L + + +L E ++ +++ +E + Q
Sbjct: 589 EKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQ 648
Query: 507 AKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSS 544
A+ QL Q + + +KK + L + E + K+K++
Sbjct: 649 AEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTA 686
Score = 32.7 bits (73), Expect = 1.9
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 3/100 (3%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKL 509
K ++ +K ND+++ K + V L + D V L EL S++ +EK + L K
Sbjct: 541 KMDILFKKLKQKFNDLVAEKEAVSSECVNLAK-DNEV--LHQELLSMRNVQEKCEKLEKD 597
Query: 510 YSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNV 549
L +E LN+ M+K +L + + +L A+ +
Sbjct: 598 KKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEI 637
>7297853_1 [S] KOG3528 FOG: PDZ domain
Length = 1658
Score = 33.5 bits (75), Expect = 1.1
Identities = 26/97 (26%), Positives = 41/97 (41%), Gaps = 14/97 (14%)
Query: 460 SLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQ------- 512
S + K + V E+Y K +LE + +E ++ Q L L SQ
Sbjct: 174 SCSEKLAELKKERNMVAVEREKYKKSYIELEKDRNYYRERGDENQKLKVLLSQESKNVLS 233
Query: 513 -------LRQEHLNILKKMKKTQDDLAEAESEVKKLK 542
L E N+L++ +K DDL A E+++LK
Sbjct: 234 LTEELNQLLSEKDNVLQEHQKMSDDLVLANKEIERLK 270
>SPAC26F1.09 [R] KOG1102 Rab6 GTPase activator GAPCenA and related TBC domain
proteins
Length = 1031
Score = 33.1 bits (74), Expect = 1.4
Identities = 38/151 (25%), Positives = 65/151 (42%), Gaps = 9/151 (5%)
Query: 461 LQNDIMS-FKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLN 519
+Q D++ + N+Y+ ++L+ + LE K E + L+ + L+ EH N
Sbjct: 868 IQPDVLDRYGNEYD---ILLKSEHELDSSLEEMRNRHKSLNEHFIMLSDSMANLQVEHEN 924
Query: 520 ILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMI---LKSLV 576
+ + K + L E LKS S K E E+ D +I L+ +V
Sbjct: 925 MSALLLKEKMYLKNQTVEQASLKSEIASLNSQLAKQKSEIEQAFQGDMEAIIAENLEIMV 984
Query: 577 ESSIKSLQDPIASLDVSDLATDLSNAFIDGD 607
ES +SL+D I + T ++ A +D D
Sbjct: 985 ES--QSLEDEIFRKEKQLAETKVNLAVLDED 1013
>Hs7705861 [B] KOG1973 Chromatin remodeling protein contains PHD Zn-finger
Length = 249
Score = 33.1 bits (74), Expect = 1.4
Identities = 29/135 (21%), Positives = 62/135 (45%), Gaps = 10/135 (7%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKR--VQKLESELESVKEFKEKYQSLAKLYS 511
+ Q+T L+ +I +Y L +K +++++ KEF + LA
Sbjct: 31 LDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTY 90
Query: 512 QLRQEHLNILKKMKKTQDDLA--EAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSG 569
++ +H+ ++ DLA EA+ + K+++SS + + KG +++E+ R+
Sbjct: 91 EMVDKHI------RRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARAR 144
Query: 570 MILKSLVESSIKSLQ 584
K+ E + K+ Q
Sbjct: 145 SKGKNSDEEAPKTAQ 159
>Hs7661774 [U] KOG4442 Clathrin coat binding protein/Huntingtin interacting
protein HIP1 involved in regulation of endocytosis
Length = 591
Score = 33.1 bits (74), Expect = 1.4
Identities = 36/119 (30%), Positives = 54/119 (45%), Gaps = 16/119 (13%)
Query: 492 ELESVK-EFKEKYQSLAKLYSQLRQ----EHLNILKKMKKTQDDLAEAESEVKKLKSSAL 546
+LE+V E +E+ QS L QL + NI T + A+AE E K+ + L
Sbjct: 461 QLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTKL 520
Query: 547 SNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFID 605
I + E E D VES +S + P ++D+SDLAT L +++ D
Sbjct: 521 EEP-INEETPSQDEEEGVSD---------VESE-RSQEQPDKTVDISDLATKLLDSWKD 568
>Hs7304923 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI large subunit
(contains heterochromatin localization PHD and BROMO
domains)
Length = 1972
Score = 33.1 bits (74), Expect = 1.4
Identities = 53/211 (25%), Positives = 95/211 (44%), Gaps = 11/211 (5%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
+++ + Q + ++ SF++Q ++ QV+ +Q Q +++ ESV + QS
Sbjct: 125 QEKRIHQPLPLAFESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTG- 183
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
L S ++ L + + K+T L +V K + S ++ S+RE+ K
Sbjct: 184 LVSNVKPLSL-VNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAF 242
Query: 569 GMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDI-NTIVNILPEFVSLLLRCPQ 627
LK + S KSL+ IA+L + AT S A + N N P + LL Q
Sbjct: 243 PSQLKK--QESSKSLKKVIAALS-NPKATSSSPAHPKQTLENNHPN--PFLTNALLGNHQ 297
Query: 628 E---MQTIAEDFLRCLSSAKQTDSVINANIA 655
+Q++ ++ L++ + S IN NIA
Sbjct: 298 PNGVIQSVIQEAPLALTTKTKMQSKINENIA 328
>Hs21553341 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein) and related
proteins
Length = 6885
Score = 33.1 bits (74), Expect = 1.4
Identities = 47/187 (25%), Positives = 75/187 (39%), Gaps = 27/187 (14%)
Query: 451 EALIQQKTAS----LQNDIMSFKNQYERDQVMLEQYDKRVQKL----ESELESVK----- 497
E +++Q +S +Q + NQ++ + Y +KL E L+S +
Sbjct: 2098 ETIMKQAESSEAPLVQKTLTDISNQWDNTLHLASTYLSHQEKLLLEGEKYLQSKEDLRLM 2157
Query: 498 --EFKEKYQSLAKLYSQLRQE--HLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRN 553
E K+K ++ L L+++ L I KK K DL E+K + L
Sbjct: 2158 LIELKKKQEAGFALQHGLQEKKAQLKIYKKFLKKAQDLTSLLKELKSQGNYLLECT---- 2213
Query: 554 NNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVN 613
K S EE + +K L ES ++ LQD + +LD D + T+ N
Sbjct: 2214 --KNPSFSEEP----WLEIKHLHESLLQQLQDSVQNLDGHVREHDSYQVCVTDLNTTLDN 2267
Query: 614 ILPEFVS 620
EFVS
Sbjct: 2268 FSKEFVS 2274
Score = 31.6 bits (70), Expect = 4.2
Identities = 20/92 (21%), Positives = 42/92 (44%), Gaps = 11/92 (11%)
Query: 456 QKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQ 515
Q+T L DI +N + +L+ K+ + + E+E++K+ Y +Q
Sbjct: 3968 QRTNQLLQDIKLLENVTQEQNELLKVVIKQTNEWDEEIENLKQILNNYS------AQFSL 4021
Query: 516 EHLNILKKMKKTQDDLAEAESEVKKLKSSALS 547
EH++ D L + + E+++++ LS
Sbjct: 4022 EHMS-----PDQADKLPQLQGEIERMEKQILS 4048
>ECU11g1420 [O] KOG1051 Chaperone HSP104 and related ATP-dependent Clp
proteases
Length = 851
Score = 33.1 bits (74), Expect = 1.4
Identities = 26/93 (27%), Positives = 49/93 (51%), Gaps = 8/93 (8%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E + ++ QK+ + DI +++ Q EQ K+++++ ELE V K Q + +
Sbjct: 395 EPQEILNQKSKAWGLDIAKTSLEFDLSQKKDEQTLKKLKEVVEELEKV---KASLQPMEE 451
Query: 509 LYSQLRQEHLNILKKMKKTQDD----LAEAESE 537
Y + ++H+ KK+KK +D LA+AE +
Sbjct: 452 AYLR-DKKHIIEAKKLKKKLEDTKLRLAQAERD 483
>CE21051 [S] KOG4744 Uncharacterized conserved protein
Length = 470
Score = 33.1 bits (74), Expect = 1.4
Identities = 23/95 (24%), Positives = 38/95 (39%), Gaps = 1/95 (1%)
Query: 473 ERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLY-SQLRQEHLNILKKMKKTQDDL 531
+ + + + YD +K +S KE E Q AK Y Q +++ + L +K DD
Sbjct: 153 DAEDAIKDTYDSAKEKASDAFDSAKEHGEDAQESAKEYFEQAKEKASDALDSAQKHGDDA 212
Query: 532 AEAESEVKKLKSSALSNVGIRNNNKGESEREEAKD 566
E+ + S + GE + AKD
Sbjct: 213 KESAQGYFEQAKDKSSEIWDSAKKHGEEASDSAKD 247
>CE09197 [Z] KOG0161 Myosin class II heavy chain
Length = 872
Score = 33.1 bits (74), Expect = 1.4
Identities = 41/227 (18%), Positives = 97/227 (42%), Gaps = 30/227 (13%)
Query: 452 ALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYS 511
AL+++ L+ + K + + V LE + ++ + +EL+ +K LY
Sbjct: 367 ALLERAREQLERQVGELKVRIDEITVELEAAQRELRAVNAELQKMKH----------LYE 416
Query: 512 QLRQEHLNILKKMKKTQDDLAEAESEV----KKLKSSALSNVGIRNN--------NKGES 559
+ ++ + ++ KK D+L EA+ + +KL L N + + ++
Sbjct: 417 KAVEQKEALARENKKLHDELHEAKEALADANRKLHELDLENARLAGEIRELQTALKEADA 476
Query: 560 EREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFV 619
+R +A++R+ L L I+ + L + + + +I+ ++ L +
Sbjct: 477 QRRDAENRAQRALAELQALRIEMER----RLQEKEEEMEALRKNLQFEIDRLIAALADAE 532
Query: 620 SLLLRCPQEMQTIAEDFLRCLSSAKQT-DSVINANIAFQEKLKRLGE 665
+ R E+ + + + ++ + T D++ ANI Q+ +K+ E
Sbjct: 533 A---RMKSEISRLKKKYQAEIAELEMTVDNLNRANIEAQKTIKKQSE 576
>At2g27170 [D] KOG0964 Structural maintenance of chromosome protein 3 (sister
chromatid cohesion complex Cohesin subunit SMC3)
Length = 1200
Score = 33.1 bits (74), Expect = 1.4
Identities = 24/110 (21%), Positives = 49/110 (43%), Gaps = 9/110 (8%)
Query: 480 EQYDKRVQKLESEL--ESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESE 537
+Q DK+ + LE + + + + +EK + + ++ +E + +++K QDD +
Sbjct: 251 QQLDKQRKSLEYTIYDKELHDAREKLEQVEVARTKASEESTKMYDRVEKAQDDSKSLDES 310
Query: 538 VKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPI 587
+K+L E E EA+ + K+ +E +K QD I
Sbjct: 311 LKELTKEL-------QTLYKEKETVEAQQTKALKKKTKLELDVKDFQDRI 353
>7303132 [BD] KOG0933 Structural maintenance of chromosome protein 2
(chromosome condensation complex Condensin subunit E)
Length = 1179
Score = 33.1 bits (74), Expect = 1.4
Identities = 33/153 (21%), Positives = 67/153 (43%), Gaps = 16/153 (10%)
Query: 451 EALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEK----YQSL 506
+ IQQ ++ M+ KN E D+ L + + + K++ E ES+KE + Y+
Sbjct: 321 QGTIQQDEKKIR---MASKN-IEDDERALAKKEADMAKVQGEFESLKEADARDSKAYEDA 376
Query: 507 AKLYSQLRQ--------EHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGE 558
K + Q E + +++ ++ +EA++ +K + G+ +GE
Sbjct: 377 QKKLEAVSQGLSTNENGEASTLQEQLIVAKEQFSEAQTTIKTSEIELRHTRGVLKQREGE 436
Query: 559 SEREEAKDRSGMILKSLVESSIKSLQDPIASLD 591
++ +A L + IK+L+ + SLD
Sbjct: 437 TQTNDAAYVKDKKLHDQLVVEIKNLERQLQSLD 469
Score = 31.2 bits (69), Expect = 5.4
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 20/124 (16%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVK--------EFKEKYQSL 506
+Q+ +LQ +I + E + ++ ++K ++EL+++K E E Q++
Sbjct: 814 EQEFETLQLEITELQKSIETAKKQHQEMIDNLEKFKAELDALKVNSSSAASEVTELEQAI 873
Query: 507 AKLYSQLR---QEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREE 563
+ +LR +E N L K +K + E E EVKK ++ K S+ +E
Sbjct: 874 KEQKDKLRDQNKEMRNQLVKKEKMLKENQEIELEVKKKEN---------EQKKISSDAKE 924
Query: 564 AKDR 567
AK R
Sbjct: 925 AKKR 928
>7300685 [T] KOG4370 Ral-GTPase effector RLIP76
Length = 625
Score = 33.1 bits (74), Expect = 1.4
Identities = 30/131 (22%), Positives = 58/131 (43%), Gaps = 1/131 (0%)
Query: 497 KEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNK 556
KE +EK + ++ S+ +E ++ K+K+ + D + E KK + +K
Sbjct: 96 KEKREKSRDKSEKDSKHAEEEPSVSHKVKEKERDKEKDRDEPKKKDKEEKRKEKDKKADK 155
Query: 557 GESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILP 616
+ + +++K S + +L P+ + VS LAT+ S DI +V
Sbjct: 156 KDKKDKKSKQLSQQQDDVSAAEEVLALGYPVFGVSVS-LATERSRCHDGVDIPLVVRDCI 214
Query: 617 EFVSLLLRCPQ 627
+F+ L+C Q
Sbjct: 215 DFLQDHLKCEQ 225
>YDR320c_1 [R] KOG1124 FOG: TPR repeat
Length = 519
Score = 33.1 bits (74), Expect = 1.4
Identities = 26/87 (29%), Positives = 45/87 (50%), Gaps = 8/87 (9%)
Query: 472 YERDQVMLEQY-DKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDD 530
Y D ++++ D + +L S S++E E Y++ + +L ILK +K ++D
Sbjct: 132 YNGDDALVDEVKDMEIARLMSLGLSIEEATEFYEN-----DVTYERYLEILKSKQKERND 186
Query: 531 LA--EAESEVKKLKSSALSNVGIRNNN 555
LA + ES +K KS + VG +NN
Sbjct: 187 LAIRKKESGIKMEKSGLSNIVGTDSNN 213
>Hs18573626_1 [R] KOG0504 FOG: Ankyrin repeat
Length = 653
Score = 33.1 bits (74), Expect = 1.4
Identities = 33/129 (25%), Positives = 61/129 (46%), Gaps = 12/129 (9%)
Query: 463 NDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILK 522
+D+M+ K V L + D V L EL S+++ +EK + L K L +E LN+
Sbjct: 342 DDLMAEKEAVSSKCVNLAK-DNEV--LHQELLSMRKVQEKCEKLEKDKKMLEEEVLNLKT 398
Query: 523 KMKKTQDDLAEAESEVKKLKSSA------LSNVGIRNNNKGESEREEA-KDRSGMILKSL 575
M+K +L +A+ +L A L + ++ + E + E+ KD + + K
Sbjct: 399 HMEKDMVELGKAQEYKSELDERAMQAIEKLEEIHLQEQAEYEKQLEQLNKDNTASLKKK- 457
Query: 576 VESSIKSLQ 584
E ++K ++
Sbjct: 458 -ELTVKDVE 465
>YPR141c [Z] KOG0239 Kinesin (KAR3 subfamily)
Length = 729
Score = 32.7 bits (73), Expect = 1.9
Identities = 33/144 (22%), Positives = 70/144 (47%), Gaps = 9/144 (6%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLR 514
+ + ASL + I +N+ + L++ V+ + + +E+ +YQS K +L
Sbjct: 217 ENERASLLDKIEEVRNKITMNPSTLQEMLNDVE--QKHMLEKEEWLTEYQSQWKKDIELN 274
Query: 515 QEHLNILKKMKKTQDDLAEAE-SEVKKL---KSSALSNVGIRNNNKGESEREEAKDRSGM 570
+H+ ++ +KK ++ + E +E KKL K +A + ++ K E E +D +
Sbjct: 275 NKHMQEIESIKKEIENTLKPELAEKKKLLTEKRNAYEAIKVKVKEK-EEETTRLRDEVAL 333
Query: 571 ILKSLVES--SIKSLQDPIASLDV 592
K+ +E+ IK L++ I ++
Sbjct: 334 KQKTNLETLEKIKELEEYIKDTEL 357
>YOL145c [P] KOG2002 TPR-containing nuclear phosphoprotein that regulates K(+)
uptake
Length = 1077
Score = 32.7 bits (73), Expect = 1.9
Identities = 20/100 (20%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Query: 469 KNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQ 528
+N+ + M ++ + R KLE + E ++ +++ Q + ++ +E + I + K
Sbjct: 919 ENELKEQGWMKQEEEARRLKLEKQAEEYRKLQDEAQKIFQV-----REAMAISEHNVKDD 973
Query: 529 DDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
DL++ ++E + + + N GES+R +A ++
Sbjct: 974 SDLSDKDNEYDEEQPRQKRKRSTKTKNSGESKRRKAAKKT 1013
>YKL114c [L] KOG3997 Major apurinic/apyrimidinic endonuclease/3'-repair
diesterase APN1
Length = 367
Score = 32.7 bits (73), Expect = 1.9
Identities = 23/72 (31%), Positives = 36/72 (49%), Gaps = 1/72 (1%)
Query: 488 KLESELESVKEFKEKYQSLAKLYSQLRQEHLNILK-KMKKTQDDLAEAESEVKKLKSSAL 546
K ESEL KE+KEK +L KL ++ R+E L+ + K KK ++ + + L
Sbjct: 296 KSESELLEDKEYKEKNDTLQKLGAKSRKEQLDKFEVKQKKRAGGTKRKKATAEPSDNDIL 355
Query: 547 SNVGIRNNNKGE 558
S + + K E
Sbjct: 356 SQMTKKRKTKKE 367
>SPCC576.13 [S] KOG4776 Uncharacterized conserved protein BCNT
Length = 215
Score = 32.7 bits (73), Expect = 1.9
Identities = 24/109 (22%), Positives = 54/109 (49%), Gaps = 14/109 (12%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK- 508
K A + + +L+N ++ KN+ ER+ ++ Q + +E ++S E + K LA+
Sbjct: 56 KIATSESEDVTLKN--IAKKNKRERNDKLIPQQSNESEAIEKPVQSTTEVELKTNELAES 113
Query: 509 -----------LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSAL 546
Y++ ++ ++++K +K+ D + A+ +KK K + L
Sbjct: 114 NSSVAVEGDENSYAETPKKKHSLIRKRRKSPLDSSSAQKVLKKNKLNTL 162
>SPBC146.03c [BD] KOG0996 Structural maintenance of chromosome protein 4
(chromosome condensation complex Condensin subunit C)
Length = 1324
Score = 32.7 bits (73), Expect = 1.9
Identities = 26/103 (25%), Positives = 55/103 (53%), Gaps = 9/103 (8%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQ-------KLESELESVKEFKEK 502
K+ L+Q SL+ + + ++E+ + + + ++ V+ K++++ S K+ ++
Sbjct: 371 KKTLVQNLLNSLEGKLQAHLEKFEQTERDISEKNEEVKSLREKAAKVKNDCTSEKKTRQS 430
Query: 503 Y-QSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSS 544
Y Q K+ QL+ LN KK+KK+ + L+ +SE + SS
Sbjct: 431 YEQQTVKIEEQLKFL-LNKEKKLKKSIEALSFEKSEAENSLSS 472
>Hs4827054 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 1118
Score = 32.7 bits (73), Expect = 1.9
Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 23/123 (18%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E++A I +TA L KN+ E K +++ + E + K KE+ + AK
Sbjct: 460 EEKARIHAETALLME-----KNKQE----------KELRERQQEEQKEKLRKEEQEQKAK 504
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSN------VGIRNNNKGESERE 562
+ E I +K +K ++++ + ESE K + S G++ +K E E
Sbjct: 505 --KKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKETSAKRGKEITGVKRQSKSEHETS 562
Query: 563 EAK 565
+AK
Sbjct: 563 DAK 565
>Hs4507649 [Z] KOG1003 Actin filament-coating protein tropomyosin
Length = 284
Score = 32.7 bits (73), Expect = 1.9
Identities = 17/100 (17%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E++ +Q+K ++++ + + Q LEQ +K+ E+++ S+ + Q + +
Sbjct: 41 EEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASL---NRRIQLVEE 97
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSN 548
+ ++ L+K+++ + E+E +K +++ A+ +
Sbjct: 98 ELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKD 137
>Hs22058210 [W] KOG1574 Predicted cell growth/differentiation regulator
contains RA domain
Length = 392
Score = 32.7 bits (73), Expect = 1.9
Identities = 26/117 (22%), Positives = 57/117 (48%), Gaps = 14/117 (11%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLR 514
Q+ ++L+ +I+ + + +R+ V +E+ + +L+ E E+ K+ K++ Q ++R
Sbjct: 196 QKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQ-------EIR 248
Query: 515 QEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMI 571
Q+ K+K D LA+ + L++ L R + + EE K + G +
Sbjct: 249 QKITECENKLK---DYLAQIRTMESGLEAEKLQ----REVQEAQVNEEEVKGKIGKV 298
>Hs22052011 [O] KOG2177 Predicted E3 ubiquitin ligase
Length = 915
Score = 32.7 bits (73), Expect = 1.9
Identities = 23/90 (25%), Positives = 45/90 (49%), Gaps = 2/90 (2%)
Query: 457 KTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQE 516
+ ++L I + K Q L++ R++ SE+ES F ++ +K +L ++
Sbjct: 380 EVSTLDTAISAVKVQLAEFLENLQEKSLRIEAFVSEIESF--FNTIEENCSKNEKRLEEQ 437
Query: 517 HLNILKKMKKTQDDLAEAESEVKKLKSSAL 546
+ ++KK+ D+ A++ EVKK K L
Sbjct: 438 NEEMMKKVLAQYDEKAQSFEEVKKKKMEFL 467
>Hs13259510 [DZ] KOG0971 Microtubule-associated protein dynactin DCTN1/Glued
Length = 1278
Score = 32.7 bits (73), Expect = 1.9
Identities = 36/176 (20%), Positives = 77/176 (43%), Gaps = 37/176 (21%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESE-------LESVKE-- 498
++KE + +++ SLQ ++ + K + + LE +++ S+ L+ ++E
Sbjct: 309 LDKE-MAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQN 367
Query: 499 --FKEKYQSLAKLYSQLRQEHLNILKKMKK--------------TQDDLAEAESEVKKLK 542
K+ + L S +QEH+ + K M+K Q++L++AES + +LK
Sbjct: 368 ARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELK 427
Query: 543 SSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATD 598
+ +G E E DR+ +E ++ L++ + L+ + D
Sbjct: 428 EQVDAALG------AEEMVEMLTDRN-----LNLEEKVRELRETVGDLEAMNEMND 472
>Hs13259508 [DZ] KOG0971 Microtubule-associated protein dynactin DCTN1/Glued
Length = 1144
Score = 32.7 bits (73), Expect = 1.9
Identities = 36/176 (20%), Positives = 77/176 (43%), Gaps = 37/176 (21%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESE-------LESVKE-- 498
++KE + +++ SLQ ++ + K + + LE +++ S+ L+ ++E
Sbjct: 175 LDKE-MAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQN 233
Query: 499 --FKEKYQSLAKLYSQLRQEHLNILKKMKK--------------TQDDLAEAESEVKKLK 542
K+ + L S +QEH+ + K M+K Q++L++AES + +LK
Sbjct: 234 ARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELK 293
Query: 543 SSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATD 598
+ +G E E DR+ +E ++ L++ + L+ + D
Sbjct: 294 EQVDAALG------AEEMVEMLTDRN-----LNLEEKVRELRETVGDLEAMNEMND 338
>CE25102 [B] KOG4364 Chromatin assembly factor-I
Length = 479
Score = 32.7 bits (73), Expect = 1.9
Identities = 31/140 (22%), Positives = 67/140 (47%), Gaps = 15/140 (10%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLA 507
+E+E ++++K L+ D ++ + + ++++ E+ DK++++ + + E KE +EK +
Sbjct: 108 IERERILEEKR--LEKDKLAEEKRLDKEKKEKERLDKKLEEDKKKEEKRKEAEEKKKKDE 165
Query: 508 KLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDR 567
+ + +E K KK +++ EA+ + K A K E EE K R
Sbjct: 166 EEKMKKDEER----NKRKKEEEEKKEAKRREDEEKKEA--------KRKEEEAIEERKRR 213
Query: 568 -SGMILKSLVESSIKSLQDP 586
S + K + K + +P
Sbjct: 214 QSALFAKFFSKVEKKKVAEP 233
Score = 32.0 bits (71), Expect = 3.2
Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 14/100 (14%)
Query: 469 KNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQ 528
K + ER+++ LE+ KL E KE KEK + KL ++ KK +
Sbjct: 105 KQRIERERI-LEEKRLEKDKLAEEKRLDKEKKEKERLDKKL------------EEDKKKE 151
Query: 529 DDLAEAESEVKKLKSSALSNVGIRNNNKG-ESEREEAKDR 567
+ EAE + KK + + RN K E E++EAK R
Sbjct: 152 EKRKEAEEKKKKDEEEKMKKDEERNKRKKEEEEKKEAKRR 191
>CE12324 [Z] KOG4280 Kinesin-like protein
Length = 670
Score = 32.7 bits (73), Expect = 1.9
Identities = 31/113 (27%), Positives = 51/113 (44%), Gaps = 27/113 (23%)
Query: 455 QQKTASLQNDIMSFKNQYER-----DQVMLEQYDKRVQKLESE----------------L 493
Q A LQ D+ S + YER D + E+ K++Q+L+ + +
Sbjct: 370 QTSKAELQKDLESLRADYERANANLDNLNPEEAAKKIQQLQDQFIGGEEAGNTQLKQKRM 429
Query: 494 ESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDL----AEAESEVKKLK 542
+ +KE + K Q LA + + + L L+ TQ+ L ++ E EVKK K
Sbjct: 430 KQLKEAETKTQKLAAALNVHKDDPL--LQVYSTTQEKLDAVTSQLEKEVKKSK 480
>CE03665 [Z] KOG0161 Myosin class II heavy chain
Length = 1968
Score = 32.7 bits (73), Expect = 1.9
Identities = 24/113 (21%), Positives = 54/113 (47%)
Query: 481 QYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKK 540
QY+K + + + ++V + +EK + L + +L +E ++L +++ ++ E E +
Sbjct: 864 QYEKLQETVATLKDTVVQEEEKKRQLQEGAERLNKETADLLAQLEASKGSTREVEERMTA 923
Query: 541 LKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVS 593
+ ++ G + + E EEA+ K LVE+ L+ +D+S
Sbjct: 924 MNEQKVALEGKLADASKKLEVEEARAVEINKQKKLVEAECADLKKNCQDVDLS 976
>At5g61460 [L] KOG0250 DNA repair protein RAD18 (SMC family protein)
Length = 1057
Score = 32.7 bits (73), Expect = 1.9
Identities = 27/125 (21%), Positives = 52/125 (41%), Gaps = 16/125 (12%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E EAL LQ +IM LE+ D++ LE +KE + K L
Sbjct: 706 EIEALPSSSVNELQREIMKD----------LEEIDEKEAFLEKLQNCLKEAELKANKLTA 755
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNN------NKGESERE 562
L+ +R+ + ++ +++L + E +++ ++ + I N E+ E
Sbjct: 756 LFENMRESAKGEIDAFEEAENELKKIEKDLQSAEAEKIHYENIMKNKVLPDIKNAEANYE 815
Query: 563 EAKDR 567
E K++
Sbjct: 816 ELKNK 820
>At5g07660 [L] KOG0250 DNA repair protein RAD18 (SMC family protein)
Length = 1058
Score = 32.7 bits (73), Expect = 1.9
Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 10/90 (11%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E +A L +IM F+ + E + +LE+ +S+KE + K L
Sbjct: 707 ETKASPTSSVNELHLEIMKFQKEIEEKESLLEKLQ----------DSLKEAELKANELKA 756
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEV 538
Y L + ++ ++K +D+L E E E+
Sbjct: 757 SYENLYESAKGEIEALEKAEDELKEKEDEL 786
Score = 30.8 bits (68), Expect = 7.1
Identities = 29/97 (29%), Positives = 47/97 (47%), Gaps = 15/97 (15%)
Query: 481 QYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMK----------KTQDD 530
Q +K + + E E++ +K ++ A S + + HL I+K K K QD
Sbjct: 685 QLEKDLTRKELEMQDLKNSVAS-ETKASPTSSVNELHLEIMKFQKEIEEKESLLEKLQDS 743
Query: 531 LAEAESEVKKLKSSALSNVGIRNNNKGESER-EEAKD 566
L EAE + +LK+ S + + KGE E E+A+D
Sbjct: 744 LKEAELKANELKA---SYENLYESAKGEIEALEKAED 777
>YMR136w [K] KOG1601 GATA-4/5/6 transcription factors
Length = 560
Score = 32.3 bits (72), Expect = 2.4
Identities = 23/83 (27%), Positives = 40/83 (47%), Gaps = 2/83 (2%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEF--KEKYQSLA 507
++++ Q SLQN I + +N+ +Q +++++ ESE ES F K K SL
Sbjct: 245 RQSIATQNFHSLQNHITTIENRLASLLTDRQQEQQQLKQQESEKESSSPFSNKIKLPSLQ 304
Query: 508 KLYSQLRQEHLNILKKMKKTQDD 530
+L + +HL K+ D
Sbjct: 305 ELTDSISTQHLPTFYDNKRHASD 327
>Hs22044126 [S] KOG4687 Uncharacterized coiled-coil protein
Length = 529
Score = 32.3 bits (72), Expect = 2.4
Identities = 46/207 (22%), Positives = 84/207 (40%), Gaps = 33/207 (15%)
Query: 471 QYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQ----LRQEHLN------- 519
Q ER + +E + +Q EL+ VKE + YQ + +Q + H N
Sbjct: 156 QLERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERLNQELNHILSGHENRIIDVDA 215
Query: 520 ILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESS 579
+ + + Q+ L + EV LKS N K ++ E K+ G +SS
Sbjct: 216 LCMENRYLQERLKQLHEEVNLLKS---------NIAKYKNALERRKNSKGQ-----GKSS 261
Query: 580 IKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCPQEMQTIAEDFLRC 639
+L +++ V DL ++ + +I ++ +LL +TI E +
Sbjct: 262 SSALTGVLSAKQVQDLLSEDHGCSLPATPQSISDLKSLATALL-------ETIHEKNM-V 313
Query: 640 LSSAKQTDSVINANIAFQEKLKRLGEI 666
+ +QT+ ++ +A EK R E+
Sbjct: 314 IQHQRQTNKILGNRVAELEKKLRTLEV 340
>Hs18378735 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 3117
Score = 32.3 bits (72), Expect = 2.4
Identities = 22/102 (21%), Positives = 52/102 (50%), Gaps = 9/102 (8%)
Query: 452 ALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYS 511
+L QQ++ SL I + + ++ERD +L +++ + LES ++ +E A++++
Sbjct: 1356 SLAQQESVSLAQIIKAQQQRHERDLALL-----KLKAEQEALESQRQLEETRNKAAQVHA 1410
Query: 512 ----QLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNV 549
Q+ Q + + +++ +A +SE +L + A +
Sbjct: 1411 ESLQQVVQSQREVTEVLQEATCKIAAQQSETARLTTDAARQI 1452
>Hs14773804 [DZ] KOG0982 Centrosomal protein Nuf
Length = 557
Score = 32.3 bits (72), Expect = 2.4
Identities = 18/91 (19%), Positives = 41/91 (44%), Gaps = 1/91 (1%)
Query: 453 LIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVK-EFKEKYQSLAKLYS 511
L+ + L+ + + R + E+ D+ Q++ LE K++ ++
Sbjct: 341 LLNARVQQLEEENTELRTTVTRLKSQTEKLDEERQRMSDRLEDTSLRLKDEMDLYKRMMD 400
Query: 512 QLRQEHLNILKKMKKTQDDLAEAESEVKKLK 542
+LRQ L K+ + TQ+ + + E++ L+
Sbjct: 401 KLRQNRLEFQKEREATQELIEDLRKELEHLQ 431
>ECU01g1160 [BD] KOG0933 Structural maintenance of chromosome protein 2
(chromosome condensation complex Condensin subunit E)
Length = 1002
Score = 32.3 bits (72), Expect = 2.4
Identities = 24/108 (22%), Positives = 48/108 (44%), Gaps = 12/108 (11%)
Query: 492 ELESVKEFKEKYQSLAKLYSQLRQEHLNILK------KMKKTQDDLAEAESEVKKLKSSA 545
++E + E +S + + LRQE+ N+L+ K K+ Q++ ++ + L
Sbjct: 570 DVEDAERLLESLESNKRKFDLLRQEYTNLLRGRALDEKRKRLQEERRSLDTRISILSGLC 629
Query: 546 LSNVGIRNNNKG------ESEREEAKDRSGMILKSLVESSIKSLQDPI 587
S + I+ + E RE+ + + K VE IK +++ I
Sbjct: 630 ESGMNIKEELRAVREKMVEGMREKNETDAFAERKRRVEDQIKEIEEKI 677
>CE28688 [T] KOG1215 Low-density lipoprotein receptors containing Ca2+-binding
EGF-like domains
Length = 2192
Score = 32.3 bits (72), Expect = 2.4
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 7/105 (6%)
Query: 67 QLFKALVLLHKVLQEGH---PSALVEGIRN--IDWIESLSRIFSVDSDDGSKYGSSRMRY 121
Q FK HK L E + P+++V N + WI+ L R S DG + R
Sbjct: 1463 QPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFE 1522
Query: 122 IGDEYAK--AIGEYVFFLVEKLQFHKSHKGFNGIFEYEEYVSLVS 164
+GD +G Y++ + + H+ HK +Y + + VS
Sbjct: 1523 LGDTPVTMDVLGGYIYLITRQGSIHRMHKFTGKTNKYVQKIREVS 1567
>CE18390 [K] KOG3119 Basic region leucine zipper transcription factor
Length = 318
Score = 32.3 bits (72), Expect = 2.4
Identities = 26/88 (29%), Positives = 48/88 (54%), Gaps = 7/88 (7%)
Query: 451 EALIQQKTASLQNDIMSFKNQYERDQVML-EQYD---KRVQKLESELESVKEFKEKYQSL 506
E + + K A + + +N+ + Q+ E+YD KR+ +LE+EL+S +E +E+ Q L
Sbjct: 228 EPIYKLKRARNNDAVRKSRNKAKELQLQKDEEYDEMKKRITQLEAELQSEREGRERDQQL 287
Query: 507 AKLYSQLRQEHLNILKKMKKTQDDLAEA 534
K QL +E + K +K+ + E+
Sbjct: 288 IK---QLIREKESTSKGPRKSSRNALES 312
>CE16096 [T] KOG2265 Nuclear distribution protein NUDC
Length = 320
Score = 32.3 bits (72), Expect = 2.4
Identities = 29/119 (24%), Positives = 58/119 (48%), Gaps = 8/119 (6%)
Query: 460 SLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQ-SLAKLYSQLR---Q 515
S + D S + ++LE++DK K E E K+ KE+ + LA+ + + +
Sbjct: 34 SRKTDFYSGAGVDQARTLLLEKFDKHGGKAMKEAEEAKKRKEEQERKLAERRAAQKAKEE 93
Query: 516 EHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESERE-EAKDRSGMILK 573
E K ++ T ++ A E E K +++ N+ +N+GE+ ++ E +D ++K
Sbjct: 94 EEFRNAKVVEVTDEEAAAFEKEQAK---NSVENLEKFVDNEGETSKDAEVEDEDSKLMK 149
>CE10372 [Z] KOG1425 Microfibrillar-associated protein MFAP1
Length = 466
Score = 32.3 bits (72), Expect = 2.4
Identities = 22/95 (23%), Positives = 48/95 (50%), Gaps = 3/95 (3%)
Query: 473 ERDQVMLEQYDKRVQK-LESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDL 531
++D++ L++ +K +K + ++E K +E+ + AKL ++ QE K+ + + DL
Sbjct: 231 KKDRITLQEAEKEKEKEILKKIEDEKRAEERKRESAKLVEKVLQEEEAAEKRKTEDRVDL 290
Query: 532 AE--AESEVKKLKSSALSNVGIRNNNKGESEREEA 564
+ + E + + A ++ + EREEA
Sbjct: 291 SSVLTDDETENMAYEAWKLREMKRLKRNRDEREEA 325
>CE07351 [S] KOG3758 Uncharacterized conserved protein
Length = 642
Score = 32.3 bits (72), Expect = 2.4
Identities = 55/226 (24%), Positives = 93/226 (40%), Gaps = 24/226 (10%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLE--SELESVKEFKEKYQSLA 507
K + QKTASL+ S +++ LE Y ++L E E E + +
Sbjct: 109 KSVDLVQKTASLKEKKASIESRCNMINEFLENYSLSSEELRELDECEQSGHLSEFFFKVL 168
Query: 508 KLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESER--EEAK 565
+ ++R+ N++++ Q LA E K K S+ I NN K E + ++
Sbjct: 169 ERCHEIRENCRNMVQE----QGHLAAFEVMEKMQKIDERSHAIICNNLKREFQNLTVDSH 224
Query: 566 DRSGMILKSLVESSIKSLQDPIASLD----VSDLATDLSNAFIDGDINTIVNILPEFVSL 621
+ ++ K+ I S D + L +S + +L N F+ +IN + +PE ++
Sbjct: 225 QKKQILSKAF---KIISQNDAVFQLAIDQYISSRSQELLNQFV--EINKMAVQMPEGLAE 279
Query: 622 LLRCPQEMQTIAEDFLRCLSSAKQTDSVI----NANIAFQEKLKRL 663
L+ +M T + KQ S I N I E LK L
Sbjct: 280 PLKAVGDMLTSIHEL---TEQEKQLFSSICSAENLPIVLDECLKSL 322
>CE06626 [DZ] KOG0971 Microtubule-associated protein dynactin DCTN1/Glued
Length = 1278
Score = 32.3 bits (72), Expect = 2.4
Identities = 31/130 (23%), Positives = 63/130 (47%), Gaps = 27/130 (20%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLA 507
+EKE L +++ SLQND+++ ++++ +E+ELE +KE A
Sbjct: 358 IEKE-LAEERADSLQNDVLTL--------------TEKLESMETELEILKEEMANGGGAA 402
Query: 508 KLYSQLRQEHLNILK-KMK----KTQD-------DLAEAESEVKKLKSSALSNVGIRNNN 555
++ + ++ + + I K+K K +D D +A E ++LK+ + + N
Sbjct: 403 QVGNSVQMKQIEIQNDKLKDALIKLRDLNAQATLDRQKAVDEAERLKTENSELIRVAENL 462
Query: 556 KGESEREEAK 565
K ++E E+K
Sbjct: 463 KRQTEIAESK 472
>CE03491 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 893
Score = 32.3 bits (72), Expect = 2.4
Identities = 24/101 (23%), Positives = 50/101 (48%), Gaps = 9/101 (8%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVML----EQYDKRVQKLESEL----ESVKEFK 500
EK + +Q T + + ++ E ++ L EQY+K+V +L E+ K+F+
Sbjct: 498 EKLSRLQHSTHAFEATLIVMNRINEDNERKLGNISEQYEKKVSELGDLKKMLDEARKKFE 557
Query: 501 EKYQSLAKLYSQLRQEHLNILKKMKKTQD-DLAEAESEVKK 540
E + + Q+ + H N ++ ++KT + +AE E ++
Sbjct: 558 EDVEQMKNSNQQVIRNHANAVESLQKTHETQIAEKNKEFER 598
>CE02914 [S] KOG2885 Uncharacterized conserved protein
Length = 472
Score = 32.3 bits (72), Expect = 2.4
Identities = 27/100 (27%), Positives = 51/100 (51%), Gaps = 9/100 (9%)
Query: 483 DKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMK---KTQDDLAEAESEVK 539
DK +QKLE + ++ E E + +A L Q + + + + +K K K +AE +E K
Sbjct: 215 DKEIQKLEDDEDN--ESPEIRRQIALLRLQKKLKEMKVERKGKGPAKVTSAMAEKMAEEK 272
Query: 540 KLKSSALSNVGIRNNNKGESEREEAKDRSGMILKSLVESS 579
+LK S + ++ +E ++ K+ + + K VES+
Sbjct: 273 RLKRRE-SKLKLKQR---RAEEKKGKEAAAQVKKETVEST 308
>At4g24580 [T] KOG4271 Rho-GTPase activating protein
Length = 790
Score = 32.3 bits (72), Expect = 2.4
Identities = 33/151 (21%), Positives = 62/151 (40%), Gaps = 4/151 (2%)
Query: 460 SLQNDIMSFKNQYERDQVMLEQYDKRVQKLESEL-ESVKEFKEKYQSLAKLYSQLRQEHL 518
+L + + F + + D +E+ + +L+S + E VK SL + L
Sbjct: 511 NLSMESIDFSVEVDEDNADIERLESTKLELQSRITEEVKSNAVLQASLERRKKALYGRRQ 570
Query: 519 NILKKMKKTQDDLAEAESEVKKL--KSSALSNVGIRNNNKGESEREEAKDRSGMILKSLV 576
+ + +KK ++A+AE+++ KL K L N ++ K A S + +
Sbjct: 571 ALEQDLKKDLQEVAQAEADIAKLEHKVDDLENRLGHHDGKASGSTHSASKESRKLPEHNA 630
Query: 577 ESSIKSLQDPIASLDVSDLATD-LSNAFIDG 606
+ K AS +S+ +T N DG
Sbjct: 631 KMKEKQKDTEAASTHISERSTSKTGNILQDG 661
>At3g54670 [D] KOG0018 Structural maintenance of chromosome protein 1 (sister
chromatid cohesion complex Cohesin subunit SMC1)
Length = 1265
Score = 32.3 bits (72), Expect = 2.4
Identities = 26/107 (24%), Positives = 51/107 (47%), Gaps = 11/107 (10%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVM------LEQYDKRVQKLESELE-SVKEFKE 501
E E L +Q+ + D+ + +N E Q + L++ KR + + E+E S ++K
Sbjct: 406 EHEVLERQR----RTDLEALRNLEENYQQLINRKNDLDEQIKRFKDRQGEIETSSSKYKN 461
Query: 502 KYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSN 548
+ SL L+++H+N + K + +AE E ++ L + N
Sbjct: 462 ETTSLKTELRALQEKHVNAREASAKLKTRIAELEDQLSDLTAERYEN 508
>At2g36070 [U] KOG2580 Mitochondrial import inner membrane translocase subunit
TIM44
Length = 499
Score = 32.3 bits (72), Expect = 2.4
Identities = 25/82 (30%), Positives = 41/82 (49%), Gaps = 6/82 (7%)
Query: 494 ESVKEFKEKYQSLAKLYSQLRQEHLNILKKM-KKTQDDLAEAESEVKKLKSS-----ALS 547
++VKEFKE+ + L + L+ +K+ K+ Q EAES KK+K S S
Sbjct: 135 KTVKEFKERAEELQGVKEDLKVRTKQTTEKLYKQGQGVWTEAESVAKKVKESFKLGKEES 194
Query: 548 NVGIRNNNKGESEREEAKDRSG 569
++ G +E E+ + +SG
Sbjct: 195 AESASSSGTGTTEGEKQQQQSG 216
>At2g02160 [S] KOG4791 Uncharacterized conserved protein
Length = 669
Score = 32.3 bits (72), Expect = 2.4
Identities = 32/105 (30%), Positives = 51/105 (48%), Gaps = 13/105 (12%)
Query: 490 ESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAE--SEVKKLKSSALS 547
+S +S +E + SL K S H + K+++D A SE+ K K +A S
Sbjct: 487 KSAPKSSREESKPEPSLGKRKSFEEDHHSH-----KRSRDSFAAPLPFSEILKRKKAAAS 541
Query: 548 NVGIRNNNKGES-EREEAKDRSGMILKSLVESSIKSLQDPIASLD 591
G RNNNK E+ +EEA D +K + E + + +P A ++
Sbjct: 542 G-GSRNNNKDETISKEEAGDE----IKLITEEKTEVVSEPKAEVE 581
>7304074 [DZU] KOG2655 Septin family protein (P-loop GTPase)
Length = 539
Score = 32.3 bits (72), Expect = 2.4
Identities = 26/115 (22%), Positives = 57/115 (48%), Gaps = 4/115 (3%)
Query: 450 KEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKL-ESELESVKEFKEKYQSLAK 508
K L Q + +++ K + E +QV + +++QKL +SELE + +E+ ++L
Sbjct: 424 KNPLTQMEEEKREHEQKMKKMEAEMEQVFDMKVKEKMQKLRDSELELARRHEERKKALEL 483
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREE 563
+L ++ ++ K+ +D E+K+ A S+ +N G+ E+++
Sbjct: 484 QIRELEEKRREFEREKKEWEDVNHVTLEELKRRSLGANSST---DNVDGKKEKKK 535
Score = 30.8 bits (68), Expect = 7.1
Identities = 20/79 (25%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Query: 466 MSFKNQYERDQVMLEQYDKRVQKLESELESV--KEFKEKYQSLAKLYSQLRQEHLNILKK 523
+S KN + + +++++++K+E+E+E V + KEK Q L +L + H K
Sbjct: 421 LSNKNPLTQMEEEKREHEQKMKKMEAEMEQVFDMKVKEKMQKLRDSELELARRHEERKKA 480
Query: 524 MKKTQDDLAEAESEVKKLK 542
++ +L E E ++ K
Sbjct: 481 LELQIRELEEKRREFEREK 499
>7295270 [D] KOG1126 DNA-binding cell division cycle control protein
Length = 900
Score = 32.3 bits (72), Expect = 2.4
Identities = 27/88 (30%), Positives = 40/88 (44%), Gaps = 7/88 (7%)
Query: 484 KRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQ------DDLAEAESE 537
+R +L S SVKE K ++A + Q R +M K +D + SE
Sbjct: 425 RRSSRLFSNSYSVKE-NNKSPNIANKFVQPRSPPRKAKSRMTKICLNNELIEDKSHHLSE 483
Query: 538 VKKLKSSALSNVGIRNNNKGESEREEAK 565
+K K +++ G NN+ G S EEAK
Sbjct: 484 KRKEKVETITSSGANNNSGGRSAAEEAK 511
>CE12968_2 [Z] KOG0244 Kinesin-like protein
Length = 1594
Score = 32.3 bits (72), Expect = 2.4
Identities = 36/167 (21%), Positives = 72/167 (42%), Gaps = 30/167 (17%)
Query: 450 KEALIQQ-KTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESEL--------------E 494
KE LI Q + A QN + YE+ L + +R++ E+E E
Sbjct: 601 KEKLIDQLERAERQNQ--QIRETYEKK---LRELMERIKDTETERDRVLNEGGKRGGNNE 655
Query: 495 SVKEFKEKYQ-SLAKLYSQLRQ------EHLNILKKMKKTQDDLAEAESEVKKLKSSALS 547
+K K++Y+ + L +L++ EHL ++ K ++ + +SEV LK + +
Sbjct: 656 QMKAIKQEYELKITDLRKELKKIEALDKEHLKVIAKSQRELQEKTRLKSEVVDLKKAKVE 715
Query: 548 NVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSD 594
+ N +K + + ++ + K E + + I +L++ D
Sbjct: 716 LIKKMNEDKKKQKTQQLANARAFATK---EKQTRLQANKIRTLEMKD 759
>YKL095w [S] KOG2989 Uncharacterized conserved protein
Length = 278
Score = 32.0 bits (71), Expect = 3.2
Identities = 27/113 (23%), Positives = 51/113 (44%), Gaps = 9/113 (7%)
Query: 451 EALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLY 510
+ L+++K QN+ M K Q + +LE KR+ K++ E +E E+ ++L K
Sbjct: 139 QRLVREKEME-QNEKMGIKEQADDKMDLLE---KRLAKIQQE----QEDDEELENLRKKN 190
Query: 511 SQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREE 563
++ Q ++ + K Q + A ++ L N R N G + E+
Sbjct: 191 LEMSQ-RAEMINRSKHAQQEKAVTTDDLDNLVDQVFDNHRQRTNKPGNNNDEK 242
>YJR045c [O] KOG0102 Molecular chaperones mortalin/PBP74/GRP75 HSP70
superfamily
Length = 654
Score = 32.0 bits (71), Expect = 3.2
Identities = 30/127 (23%), Positives = 51/127 (39%), Gaps = 17/127 (13%)
Query: 453 LIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQ 512
L + + + ND FK+Q E + +E +K Q S+KEF+ K + K +Q
Sbjct: 530 LSENEIEQMVNDAEKFKSQDEARKQAIETANKADQLANDTENSLKEFEGK---VDKAEAQ 586
Query: 513 LRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIR--------------NNNKGE 558
++ + LK++ E +E K K+ L ++ NNN
Sbjct: 587 KVRDQITSLKELVARVQGGEEVNAEELKTKTEELQTSSMKLFEQLYKNDSNNNNNNNGNN 646
Query: 559 SEREEAK 565
+E E K
Sbjct: 647 AESGETK 653
>SPBC21D10.10 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalytic subunit
PCAF/GCN5 and related proteins
Length = 299
Score = 32.0 bits (71), Expect = 3.2
Identities = 41/183 (22%), Positives = 73/183 (39%), Gaps = 33/183 (18%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESEL------ESVKEFKEKYQSLAK 508
++K SL ++ K + DQ+ LE+ DK +K ++E +S++ K+ + A
Sbjct: 100 EKKLESLYEEVAKAKAKAVEDQLALEEADKEAKKAKTEAPVEAANKSLRSRKKTPEIAAP 159
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNV-GIRNNNKGES-----ERE 562
+ + E K KK E + +KK +S+ L + I N+ G R+
Sbjct: 160 --ANIEPEVAPTTKTPKKRAALSNEEKQSLKKFQSAMLPMLDNISNHRFGAPFSHPVNRK 217
Query: 563 EAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLL 622
EA D ++ K DL T L N +G+I + + E + +
Sbjct: 218 EAPDYDSLVYKP------------------QDLRT-LKNMIKEGNITEVDELYREVLRIF 258
Query: 623 LRC 625
C
Sbjct: 259 ANC 261
>SPAC4F10.11 [DZU] KOG2655 Septin family protein (P-loop GTPase)
Length = 469
Score = 32.0 bits (71), Expect = 3.2
Identities = 14/66 (21%), Positives = 42/66 (63%), Gaps = 2/66 (3%)
Query: 482 YDKRVQKLESELESV--KEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVK 539
+++++ K+E+E++++ ++ +EK L + ++LR H + ++K + DL + ++ +
Sbjct: 393 HEEKLMKMEAEMKTIFSQKVQEKEDRLKQSENELRTRHREMKAALEKQKADLIDHKNRLM 452
Query: 540 KLKSSA 545
+ K++A
Sbjct: 453 QAKAAA 458
>SPAC27D7.14c [P] KOG2002 TPR-containing nuclear phosphoprotein that regulates
K(+) uptake
Length = 1039
Score = 32.0 bits (71), Expect = 3.2
Identities = 33/130 (25%), Positives = 63/130 (48%), Gaps = 12/130 (9%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQ-KLESELESVKEFKEKYQSLAK---L 509
I+Q+ +N + K Q ER +Y+K V KLE ++ KEK + LA+ L
Sbjct: 838 IEQRAKMAKN---TTKRQLERAIQAQIEYEKSVAAKLEDA--RIQREKEKARRLAEEEAL 892
Query: 510 YSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSG 569
+ ++ + ++ +K Q+++ E +K +S + ++ + +S +++ KDR
Sbjct: 893 LKEKQERERQLQEERQKMQEEVLEWRKSQQKASEDDMS---LSDDEEKQSGKKKKKDRKK 949
Query: 570 MILKSLVESS 579
KS ESS
Sbjct: 950 RKSKSKQESS 959
>Hs6005938 [NTZ] KOG4286 Dystrophin-like protein
Length = 3433
Score = 32.0 bits (71), Expect = 3.2
Identities = 40/183 (21%), Positives = 82/183 (43%), Gaps = 38/183 (20%)
Query: 486 VQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSA 545
++KLE+++E++ +F EK HL + +K ++ A+ E +++
Sbjct: 1775 LEKLENDIENMLKFVEK--------------HLESSDEDEKMDEESAQIEEVLQR----- 1815
Query: 546 LSNVGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATDLSNAFID 605
G ++ + ++ K R ++L + IK++ PI + LA+ + ++ +
Sbjct: 1816 ----GEEMLHQPMEDNKKEKIRLQLLLLHTRYNKIKAI--PIQQRKMGQLASGIRSSLLP 1869
Query: 606 GDINTIVN---ILPEFVSLLLRCPQEMQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKR 662
D +N + + V L L P+ I EDF + Q DS+ N +++L +
Sbjct: 1870 TDYLVEINKILLCMDDVELSLNVPELNTAIYEDF------SFQEDSLKN----IKDQLDK 1919
Query: 663 LGE 665
LGE
Sbjct: 1920 LGE 1922
>Hs4758650 [Z] KOG0240 Kinesin (SMY1 subfamily)
Length = 957
Score = 32.0 bits (71), Expect = 3.2
Identities = 38/216 (17%), Positives = 93/216 (42%), Gaps = 15/216 (6%)
Query: 454 IQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQL 513
++Q+ + S + YE+ Q E+ + + E+ + VKE + + LA Y Q
Sbjct: 445 LKQQMLDQDELLASTRRDYEKIQ---EELTRLQIENEAAKDEVKEVLQALEELAVNYDQK 501
Query: 514 RQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRSGMILK 573
QE + + ++ D+LA+ + + + LS + +N+ +++ A + ++LK
Sbjct: 502 SQEVEDKTRANEQLTDELAQKTTTLTTTQRE-LSQLQELSNH----QKKRATEILNLLLK 556
Query: 574 SLVE-------SSIKSLQDPIASLDVSDLATDLSNAFIDGDINTIVNILPEFVSLLLRCP 626
L E + +K+L D ++ L + + ++ ++VN + S +
Sbjct: 557 DLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSN 616
Query: 627 QEMQTIAEDFLRCLSSAKQTDSVINANIAFQEKLKR 662
++M + C Q ++ I + + + +++
Sbjct: 617 RKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQ 652
>Hs22065277 [Z] KOG4807 F-actin binding protein regulates actin cytoskeletal
organization
Length = 1267
Score = 32.0 bits (71), Expect = 3.2
Identities = 22/105 (20%), Positives = 59/105 (55%), Gaps = 10/105 (9%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQY--ERDQVMLEQYDKRVQKLESELESV-KEFKEKYQS 505
EK+ L+ ++TA+ + I + KN + E ++ + + ++ + S++E++ +++ E+ QS
Sbjct: 985 EKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYLEELQS 1044
Query: 506 -------LAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKS 543
L++ YSQ E+ ++ + ++ + L + + E ++L +
Sbjct: 1045 VQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNA 1089
>Hs18563233 [Z] KOG1850 Myosin-like coiled-coil protein
Length = 593
Score = 32.0 bits (71), Expect = 3.2
Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 11/89 (12%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E+E ++ T+ Q+ + + Q +EQ +R KL E E EK +S+
Sbjct: 71 EEEEKRKEITSHFQSTLTDIQGQ-------IEQQSERNMKLCQENT---ELAEKLKSIID 120
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESE 537
Y +LR+EHL+ + K ++ Q L +A+ E
Sbjct: 121 QY-ELREEHLDKIFKHRELQQKLVDAKLE 148
>Hs18557432 [S] KOG4036 Uncharacterized conserved protein
Length = 267
Score = 32.0 bits (71), Expect = 3.2
Identities = 34/183 (18%), Positives = 79/183 (42%), Gaps = 13/183 (7%)
Query: 449 EKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK 508
E++ + L D +F ++ R Q ++E+ Q+ E EL+ +KE++ + +
Sbjct: 70 EEQFKFKNMVRGLDEDETNFLDEVSRQQELIEK-----QQREEELKELKEYRNNLKKVGI 124
Query: 509 LYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREEAKDRS 568
++ + K +T++ ++ + +K + + K + E ++ K++
Sbjct: 125 SQENKKEVEKKLTVKPLETKNKFSQVKLLAGAVKRKSSESDNSVKRLKPDPEPDD-KNQE 183
Query: 569 GMILKSLVESSI--KSLQDPIASLDVSDLA-----TDLSNAFIDGDINTIVNILPEFVSL 621
KSL +S+ S+ P A++ +S L + SN+ D +N + VS
Sbjct: 184 PSSCKSLRNTSLSGSSIHCPSAAVCISILPGLCTYSGSSNSESSADSEGTINATGKIVSF 243
Query: 622 LLR 624
+ +
Sbjct: 244 IFQ 246
>CE25014 [R] KOG2010 Double stranded RNA binding protein
Length = 182
Score = 32.0 bits (71), Expect = 3.2
Identities = 30/122 (24%), Positives = 55/122 (44%), Gaps = 23/122 (18%)
Query: 474 RDQVMLEQYDKRVQKLESELESVK--------EFKEKYQSLAKLYSQLRQEHLNILKKMK 525
R+Q +Y +K+E + E+ + E +++ Q + LYSQL E +L ++
Sbjct: 41 REQARQGRYQLLEKKVEEDAEAYRHDTADKVIELQDRVQQVMFLYSQLDNEKSTLLYEVD 100
Query: 526 KTQDDLAEAE--------------SEVKKLKSSALSNVGIRNNNKGE-SEREEAKDRSGM 570
+D+L E + SEVK LK + + + K E S+R++ +G+
Sbjct: 101 LLKDELEEKDASLNLSSRECRDLTSEVKALKRTIDALHASQQQLKQEISQRDQLIQENGL 160
Query: 571 IL 572
L
Sbjct: 161 CL 162
>CE22238 [S] KOG0992 Uncharacterized conserved protein
Length = 734
Score = 32.0 bits (71), Expect = 3.2
Identities = 28/127 (22%), Positives = 56/127 (44%), Gaps = 10/127 (7%)
Query: 451 EALIQQKTASLQNDIMSFKN--QYERDQVMLEQYDKRVQKLESELE--------SVKEFK 500
E+L + S Q M K Q + D+ +++QY+ ++Q +ELE V+ +
Sbjct: 236 ESLSSNLSESKQQGDMLRKQLIQAKDDKHIIQQYEVKLQTSTAELERRLRESEHDVERLR 295
Query: 501 EKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESE 560
+A + + +E+ ++L K+ QD L+ E K + G+ + + S
Sbjct: 296 TSQLEMATKFEEASRENTDLLSKIDILQDQLSLEEDRRKLCEEQIDRLKGVESFVESSSH 355
Query: 561 REEAKDR 567
R E ++
Sbjct: 356 RIEETEK 362
>CE19212 [S] KOG4643 Uncharacterized coiled-coil protein
Length = 1166
Score = 32.0 bits (71), Expect = 3.2
Identities = 24/109 (22%), Positives = 48/109 (44%), Gaps = 15/109 (13%)
Query: 470 NQYERDQVMLEQYDKRVQKLESELESVKE----FKEKYQSLAKLYSQLRQEHLNILKK-- 523
NQ + + L Q V KL S++E++ + + E+ ++L++ L ++ +L++
Sbjct: 827 NQIDELKKQLNQKISEVNKLSSKIEALSQLNRTYNEENRNLSRQLEILLTQNKELLQRAL 886
Query: 524 ---------MKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESEREE 563
MK QD L+ +KL+ + N K ER++
Sbjct: 887 HDKDQYHLEMKDFQDQLSALRRHKEKLEDKIMDQYRTMENKKSTPERKQ 935
>CE14217 [S] KOG4360 Uncharacterized coiled coil protein
Length = 607
Score = 32.0 bits (71), Expect = 3.2
Identities = 27/104 (25%), Positives = 51/104 (48%), Gaps = 13/104 (12%)
Query: 453 LIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAK---- 508
L++++ + ++S + E+ L Q + KL +EL K+ KE+ S+ K
Sbjct: 184 LLEKQLDYTNDKVISLQKLIEQKTTELNQQYENTGKLMNELAD-KDKKERMISMEKEEMG 242
Query: 509 -LYSQLRQEHLNILKKMKKTQD-------DLAEAESEVKKLKSS 544
+ ++ Q H + + K+ QD + AE ESE+ KL+S+
Sbjct: 243 AILIEMIQRHDTMQAEHKEMQDQYAELMANFAETESELNKLRST 286
>CE03287 [BD] KOG0996 Structural maintenance of chromosome protein 4
(chromosome condensation complex Condensin subunit C)
Length = 1549
Score = 32.0 bits (71), Expect = 3.2
Identities = 24/110 (21%), Positives = 52/110 (46%), Gaps = 11/110 (10%)
Query: 489 LESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQDDLAEAESEVKKLKSSALSN 548
+E+ + + EF K ++ +L Q ++ ++ D +A ++E+ K+K S
Sbjct: 304 MENPVRAAIEFLMKENEATTIHMKLEQ------RRRQRYLDKIAPKQAELDKMKEEMKSI 357
Query: 549 VGIRNNNKGESEREEAKDRSGMILKSLVESSIKSLQDPIASLDVSDLATD 598
+ NK E ++ E + + +S ++ + SL S ++SDL T+
Sbjct: 358 AETLDTNKNEYKQSEEAQKVMIEERSKLDKNFDSL-----SKELSDLGTE 402
>At5g57120 [Y] KOG2992 Nucleolar GTPase/ATPase p130
Length = 330
Score = 32.0 bits (71), Expect = 3.2
Identities = 27/125 (21%), Positives = 61/125 (48%), Gaps = 11/125 (8%)
Query: 451 EALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELES-VKEFKEKYQSLAKL 509
EA + + +++ D KN+ + +V E+ +V++ ++ +E VKE K+K ++ K+
Sbjct: 78 EANVVEAVENVKKDKKKKKNKETKVEVTEEE---KVKETDAVIEDGVKEKKKKKETKVKV 134
Query: 510 YSQLRQEHLNIL-------KKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESERE 562
+ + + + + KK KK++ EA+ + +K+ + + E + E
Sbjct: 135 TEEEKVKETDAVIEDGVKEKKKKKSKSKSVEADDDKEKVSKKRKRSEPEETKEETEDDDE 194
Query: 563 EAKDR 567
E+K R
Sbjct: 195 ESKRR 199
>7299439 [K] KOG3779 Homeobox transcription factor prospero
Length = 1703
Score = 32.0 bits (71), Expect = 3.2
Identities = 38/165 (23%), Positives = 65/165 (39%), Gaps = 38/165 (23%)
Query: 448 MEKEALIQQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLA 507
M KEA QQ+ + Q ++ Q +Q ++ ++ E E + + KE+ Q
Sbjct: 1010 MAKEAAEQQQ-----------QQQQQQQQQQQQQQQEQQRRFEQEQQEQQRRKEEQQQ-- 1056
Query: 508 KLYSQLRQEHLNILKKMKKTQDDLAEAESEVK--------------------KLKSSALS 547
Q +Q+HL L++ + Q +A A + LKS
Sbjct: 1057 --QIQRQQQHLQQLQQQQMEQQHVATAAPRPQMHHPAPARLPTRMGGAAGHTALKSELSE 1114
Query: 548 NVG-IRNNNKGESEREEAKDRSGM--ILKSLVESSIKSLQDPIAS 589
+R NN R D G+ +LKS + +S+ +L D I +
Sbjct: 1115 KFQMLRANNNSSMMRMSGTDLEGLADVLKSEITTSLSALVDTIVT 1159
>7293249 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1390
Score = 32.0 bits (71), Expect = 3.2
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 12/93 (12%)
Query: 453 LIQQKTASLQNDIMSFKNQYERDQVMLE--QYDKRVQKLESELESVKEFKEKYQSLAKLY 510
L ++K+A ++ D S + + + + ++ Q R+QKLE E +++ + +A L
Sbjct: 731 LNEEKSARIKADQHSQEKERQLSMLSVDYRQIQLRLQKLEGEC------RQESEKVAALQ 784
Query: 511 SQLRQEHLNILKKMKKTQDDLAEAESEVKKLKS 543
SQL QEH K +L+ SEV L+S
Sbjct: 785 SQLDQEH----SKRNALLSELSLHSSEVAHLRS 813
>7293243 [D] KOG0964 Structural maintenance of chromosome protein 3 (sister
chromatid cohesion complex Cohesin subunit SMC3)
Length = 1211
Score = 32.0 bits (71), Expect = 3.2
Identities = 23/99 (23%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Query: 469 KNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQ 528
K+ ++ ++ + K +K++ +++KE K+K QS + S L E +L++ K
Sbjct: 258 KSSSDKKKIYNIEIQKAQEKIKDVQKNLKEAKKKVQSTKEERSVLMTEQQQLLREKTKLD 317
Query: 529 DDLAEAESEVK-KLKSSALSNVGIRNNNKGESEREEAKD 566
+ + EV+ KS ++ ++N +ERE+ D
Sbjct: 318 LTIVDLNDEVQGDNKSKERADQELKNLKVTIAEREKELD 356
Score = 31.6 bits (70), Expect = 4.2
Identities = 17/72 (23%), Positives = 40/72 (54%), Gaps = 3/72 (4%)
Query: 469 KNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQEHLNILKKMKKTQ 528
K + + L +KR++K+ S+LE E +++ +L +L+QE ++K K+ +
Sbjct: 867 KRKLNNCKTELVSAEKRIKKVNSDLE---EIEKRVMEAVQLQKELQQELETHVRKEKEAE 923
Query: 529 DDLAEAESEVKK 540
++L + +++K
Sbjct: 924 ENLNKDSKQLEK 935
Score = 30.8 bits (68), Expect = 7.1
Identities = 26/90 (28%), Positives = 46/90 (50%), Gaps = 7/90 (7%)
Query: 455 QQKTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLR 514
++K SL N + ++ E+ L+ + R+Q LE E E +KE+ +K+ + +R
Sbjct: 181 ERKEESL-NLLRETDSKVEKISEYLKTIEDRLQTLEEEKEELKEY-QKWDKTRRTLEYIR 238
Query: 515 QEHLNILKKMKKTQDDL---AEAESEVKKL 541
E LK KK D+L ++ S+ KK+
Sbjct: 239 YE--TELKDTKKALDELQLQRKSSSDKKKI 266
>YLR383w [L] KOG0250 DNA repair protein RAD18 (SMC family protein)
Length = 1114
Score = 31.6 bits (70), Expect = 4.2
Identities = 29/137 (21%), Positives = 60/137 (43%), Gaps = 5/137 (3%)
Query: 457 KTASLQNDIMSFKNQYERDQVMLEQYDKRVQKLESELESVKEFKEKYQSLAKLYSQLRQE 516
K + + K QY+ ++ L + +Q+L+ ++ S + +KY+ Y ++
Sbjct: 794 KIEQIAQEAQPIKEQYDSTKLALVEAQDELQQLKEDINSRQSKIQKYKDDTIYYEDKKKV 853
Query: 517 HLNILKKMKKTQDDLAEAESEVKKLKSSALSNVGIRNNNKGESERE---EAKDRSGMILK 573
+L +KK++ L E + + S I N + +++ E E S MI K
Sbjct: 854 YLENIKKIEVNVAALKEGIQRQIQNACAFCSKERIENVDLPDTQEEIKRELDKVSRMIQK 913
Query: 574 SLVESSIKSLQDPIASL 590
+ E S+ Q+ + +L
Sbjct: 914 A--EKSLGLSQEEVIAL 928
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,164,036
Number of Sequences: 60738
Number of extensions: 1362330
Number of successful extensions: 7483
Number of sequences better than 10.0: 371
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 329
Number of HSP's that attempted gapping in prelim test: 6738
Number of HSP's gapped (non-prelim): 992
length of query: 679
length of database: 30,389,216
effective HSP length: 113
effective length of query: 566
effective length of database: 23,525,822
effective search space: 13315615252
effective search space used: 13315615252
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)