ORF      STATUS       Function Best COG  Functional category                                          Pathways and functional systems
r_klactIII0872  suspect: LH   TZ    KOG4406  Cytoskeleton                                                   CDC42 Rho GTPase-activating protein
r_klactIII0872  suspect: LH   TZ    KOG4406  Signal transduction mechanisms                                 CDC42 Rho GTPase-activating protein

BLASTP 2.2.3 [May-13-2002]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= r_klactIII0872  301679  303418 580  
         (580 letters)

Database: KOG eukaryal database 04/03 
           60,738 sequences; 30,389,216 total letters

Searching..................................................done

Color Key for Alignment Scores:   


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

YJL201w [TZ] KOG4406 CDC42 Rho GTPase-activating protein              459   e-129

>YJL201w [TZ] KOG4406 CDC42 Rho GTPase-activating protein
          Length = 599

 Score =  459 bits (1181), Expect = e-129
 Identities = 265/610 (43%), Positives = 375/610 (61%), Gaps = 48/610 (7%)

Query: 4   INVNVNSIFYKSYSVDPESEYPIYVFDSTYLPSFNVVDDKQVYELLIDGLMDKVLTKLPA 63
           I++NVN+IF++SYSVDP S + IYVFDSTYLP+ + + DKQVY+LLI+ LMD+++ KLP 
Sbjct: 2   IDINVNNIFFRSYSVDPNSGHAIYVFDSTYLPASDEIGDKQVYDLLINALMDRLVMKLPQ 61

Query: 64  EPFSLVVFSSGFTTNDISWVYGIKLYSKVPKNVRSLIQKTIVVHESFFVKTVFQVLKNAM 123
            P+SLV+FSSGF+   ISWVYGIK+++K+PK  +  +QK  +VHESFFV++V+QV+ NAM
Sbjct: 62  APYSLVIFSSGFSQRKISWVYGIKMFAKLPKETKFYLQKIFIVHESFFVRSVYQVISNAM 121

Query: 124 RIKDLSNKDSNTD--TVIHVPSLTALANHLDITLLRISLNVYLYDYQFNEKITIPDQYTV 181
               L +KDS  D  +++HV  LT+L+  +DIT LRISLNVYLYDYQ  E I +P++Y  
Sbjct: 122 NFNFLDSKDSQHDFPSLVHVLDLTSLSELIDITRLRISLNVYLYDYQIREHINVPEEYYN 181

Query: 182 NPGSIANRQYRQLIFDRIFKRLKVEGPKSELVFQKPGSYKKINILLDVIERNHYVDLSQW 241
               +A RQYRQL+FD+IFK+L+ +    EL+FQKPG+YKK+NI LD+I+RN+Y+DLSQW
Sbjct: 182 RLTPLAIRQYRQLVFDKIFKKLQNDALLCELIFQKPGNYKKVNIFLDIIKRNNYIDLSQW 241

Query: 242 DIYSLGSVFLN-FLKNKSKXXXXXXXXXXXVTDDLEYTKTTFKSITEYNGYYDLVRAVFP 300
           DIYSL SV+LN F+KNK+K           + DDL++T  TF+ I ++N Y DL   + P
Sbjct: 242 DIYSLASVWLNYFIKNKAKPLIPIELIPLPIVDDLKFTSETFRKIIKFNQYQDLFMVIIP 301

Query: 301 LFIDFLDNSDETKHNXXXXXXXXXXXXCKEKVSMKSSDKLSIGTRFIRNLLSQFYLVIDE 360
            F   + + + TKH+            CKEK+SM ++D+L+IG+R+I+NLL  F  +  E
Sbjct: 302 FFNRIIAHGESTKHDSRTLSKALTPALCKEKLSMMTNDRLAIGSRYIKNLLDFFPEIAKE 361

Query: 361 LDSKNAPALPARIISSTTITPPELPKPRKASPTRYXXXXXXXXXXXXAVRPRSS--SVKH 418
           + S      P+ + SS+TI  P LPKPRK+SPTRY            +  P+ S  S  +
Sbjct: 362 ISSP-----PSSVSSSSTI--PVLPKPRKSSPTRYSELGCLTLPRSRSPSPQRSVTSPTY 414

Query: 419 TP---PSTELGVSASSSNVLQEP--NALPVINLTEVPTLEPPSPFINDSRNDSTNSFDSN 473
           TP    +T +    SSS  +  P  NA P + +  V       P ++ + N +T+   + 
Sbjct: 415 TPVALQNTPVLKPKSSSRNVSSPSFNAKPPLPIKAV-----TRPQLSLTSNSNTDL--AL 467

Query: 474 GSMQRDRLRSPTRHLGKDII------TD----------------ADTNGVDEIVGLTDLL 511
            S   D L SPT+    D +      TD                 D N V+  +      
Sbjct: 468 ASSSTDTLSSPTKTPSADSLPLSNSSTDLTISDNIKEMVKDEPAKDKNSVETDI-FVQQF 526

Query: 512 DQLTIEKNAKIQSFD-XXXXXXXXXXXXSTNATRFSNEGYADISKGSKVSKLAALYEERL 570
           + LT+ +NAKI+ FD             S  A +FS +GY+DI   +KVS+LAALYEERL
Sbjct: 527 ESLTLVQNAKIKKFDKELQEKKKKNETTSKTADKFSQKGYSDIKASNKVSRLAALYEERL 586

Query: 571 QGLQAISDLK 580
           QGLQ ++++K
Sbjct: 587 QGLQVMNEMK 596


  Database: KOG eukaryal database 04/03
    Posted date:  Apr 14, 2003  1:07 PM
  Number of letters in database: 30,389,216
  Number of sequences in database:  60,738
  
Lambda     K      H
   0.316    0.134    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,722,189
Number of Sequences: 60738
Number of extensions: 1314534
Number of successful extensions: 3820
Number of sequences better than 1.0e-05: 1
Number of HSP's better than  0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 3814
Number of HSP's gapped (non-prelim): 1
length of query: 580
length of database: 30,389,216
effective HSP length: 112
effective length of query: 468
effective length of database: 23,586,560
effective search space: 11038510080
effective search space used: 11038510080
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)