ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0918 check: MH O KOG1870 Posttranslational modification, protein turnover, chaperones Ubiquitin C-terminal hydrolase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0918 314815 318570 1252
(1252 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL197w [O] KOG1870 Ubiquitin C-terminal hydrolase 853 0.0
SPCC1494.05c [O] KOG1870 Ubiquitin C-terminal hydrolase 460 e-129
SPCC16A11.12c [O] KOG1870 Ubiquitin C-terminal hydrolase 230 9e-60
Hs4759290 [O] KOG1870 Ubiquitin C-terminal hydrolase 228 4e-59
Hs14149627 [O] KOG1870 Ubiquitin C-terminal hydrolase 228 6e-59
At1g32850 [O] KOG1870 Ubiquitin C-terminal hydrolase 225 3e-58
Hs4507853 [O] KOG1870 Ubiquitin C-terminal hydrolase 215 3e-55
At4g10590 [O] KOG1870 Ubiquitin C-terminal hydrolase 209 3e-53
At2g40930 [O] KOG1870 Ubiquitin C-terminal hydrolase 204 5e-52
Hs14211903 [O] KOG1870 Ubiquitin C-terminal hydrolase 195 4e-49
Hs22065611 [O] KOG1870 Ubiquitin C-terminal hydrolase 191 5e-48
At4g10570 [O] KOG1870 Ubiquitin C-terminal hydrolase 189 2e-47
Hs4758564_2 [O] KOG1870 Ubiquitin C-terminal hydrolase 189 2e-47
CE19500 [O] KOG1870 Ubiquitin C-terminal hydrolase 182 3e-45
Hs20472401 [O] KOG1870 Ubiquitin C-terminal hydrolase 179 3e-44
CE03146 [O] KOG1870 Ubiquitin C-terminal hydrolase 172 3e-42
7293731 [O] KOG1870 Ubiquitin C-terminal hydrolase 166 2e-40
Hs4827054 [O] KOG1868 Ubiquitin C-terminal hydrolase 164 1e-39
Hs22068900 [O] KOG1870 Ubiquitin C-terminal hydrolase 153 1e-36
Hs22063256 [O] KOG1870 Ubiquitin C-terminal hydrolase 144 9e-34
YDR069c [O] KOG1868 Ubiquitin C-terminal hydrolase 143 1e-33
HsM19923759 [O] KOG1868 Ubiquitin C-terminal hydrolase 140 1e-32
Hs21361712 [O] KOG1868 Ubiquitin C-terminal hydrolase 139 3e-32
Hs22066171 [O] KOG1870 Ubiquitin C-terminal hydrolase 128 6e-29
HsM18874088 [O] KOG1870 Ubiquitin C-terminal hydrolase 126 2e-28
Hs21489975 [O] KOG1870 Ubiquitin C-terminal hydrolase 126 2e-28
7303210 [O] KOG1870 Ubiquitin C-terminal hydrolase 126 2e-28
Hs5730108 [O] KOG1870 Ubiquitin C-terminal hydrolase 125 5e-28
7295645 [O] KOG1868 Ubiquitin C-terminal hydrolase 122 5e-27
7291841 [O] KOG1870 Ubiquitin C-terminal hydrolase 120 1e-26
Hs6912742 [O] KOG1868 Ubiquitin C-terminal hydrolase 118 5e-26
Hs21265129 [O] KOG1868 Ubiquitin C-terminal hydrolase 118 5e-26
YER144c [O] KOG1868 Ubiquitin C-terminal hydrolase 117 1e-25
7300711 [O] KOG1868 Ubiquitin C-terminal hydrolase 115 3e-25
HsM7706755 [O] KOG1868 Ubiquitin C-terminal hydrolase 113 2e-24
Hs5730110 [O] KOG1867 Ubiquitin-specific protease 113 2e-24
SPBC18H10.08c [O] KOG1868 Ubiquitin C-terminal hydrolase 112 4e-24
At2g24640 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 106 2e-22
7293885 [O] KOG1867 Ubiquitin-specific protease 105 6e-22
Hs22065367 [O] KOG1867 Ubiquitin-specific protease 104 8e-22
CE26210 [O] KOG1868 Ubiquitin C-terminal hydrolase 103 2e-21
CE29636 [O] KOG1870 Ubiquitin C-terminal hydrolase 102 4e-21
CE29635 [O] KOG1870 Ubiquitin C-terminal hydrolase 102 4e-21
Hs22055583 [O] KOG1867 Ubiquitin-specific protease 101 6e-21
Hs22056581 [O] KOG1868 Ubiquitin C-terminal hydrolase 101 8e-21
ECU06g0910 [O] KOG1870 Ubiquitin C-terminal hydrolase 98 7e-20
At5g65450 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 94 1e-18
At5g10790 [O] KOG1867 Ubiquitin-specific protease 94 1e-18
At4g24560 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 93 2e-18
Hs14776897 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 93 3e-18
At4g31670 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 93 3e-18
Hs14777500 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 92 5e-18
At5g57990 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 91 9e-18
Hs8394519 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 91 1e-17
At1g17110 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 89 4e-17
YMR223w [O] KOG1867 Ubiquitin-specific protease 88 1e-16
At4g17890_2 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 88 1e-16
SPCC1682.12c [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 87 2e-16
At5g46740 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 85 6e-16
Hs14149817 [O] KOG1867 Ubiquitin-specific protease 83 3e-15
At2g32780 [O] KOG1873 Ubiquitin-specific protease 82 4e-15
Hs20540195 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 80 2e-14
Hs18557591 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 80 2e-14
Hs22044534 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 78 1e-13
Hs22044530 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 77 1e-13
Hs22044539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 77 2e-13
Hs22044565 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 77 2e-13
Hs22044559 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 77 2e-13
Hs22044555 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 77 2e-13
Hs22044551 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 77 2e-13
Hs22044543 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 77 2e-13
Hs22044541 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 77 2e-13
Hs22044537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 77 2e-13
Hs22044547 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 76 3e-13
7300926 [O] KOG1864 Ubiquitin-specific protease 75 5e-13
Hs5454156 [O] KOG1873 Ubiquitin-specific protease 75 7e-13
Hs13435157 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 75 7e-13
At3g14400 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 74 1e-12
Hs22044528 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 74 1e-12
At1g04860 [O] KOG1873 Ubiquitin-specific protease 74 1e-12
YNL186w [O] KOG1870 Ubiquitin C-terminal hydrolase 73 3e-12
CE26241 [O] KOG1867 Ubiquitin-specific protease 72 6e-12
At4g39910 [O] KOG1864 Ubiquitin-specific protease 71 9e-12
At2g22310 [O] KOG1864 Ubiquitin-specific protease 69 4e-11
Hs18860907_1 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 69 5e-11
ECU07g0410 [O] KOG1868 Ubiquitin C-terminal hydrolase 69 6e-11
Hs20548613 [O] KOG1864 Ubiquitin-specific protease 68 1e-10
Hs14732941 [Z] KOG2026 Spindle pole body protein - Sad1p 67 1e-10
Hs12383078 [O] KOG1864 Ubiquitin-specific protease 67 2e-10
CE11978 [O] KOG1870 Ubiquitin C-terminal hydrolase 67 2e-10
YIL156w [O] KOG1868 Ubiquitin C-terminal hydrolase 67 2e-10
SPBC1703.12 [O] KOG1864 Ubiquitin-specific protease 67 2e-10
SPAC13A11.04c [O] KOG1867 Ubiquitin-specific protease 67 2e-10
7295432 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 66 4e-10
ECU03g0580 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 65 7e-10
Hs22060223 [O] KOG1867 Ubiquitin-specific protease 65 9e-10
YER098w [O] KOG1864 Ubiquitin-specific protease 64 1e-09
SPBC713.02c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 64 1e-09
Hs22047537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 64 1e-09
Hs21361749 [O] KOG1867 Ubiquitin-specific protease 64 1e-09
At3g49600_2 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 64 1e-09
7302097 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 64 2e-09
SPCC188.08c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 62 4e-09
At3g11910 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 62 6e-09
7290583 [O] KOG1873 Ubiquitin-specific protease 62 6e-09
Hs11641425 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 62 7e-09
Hs11641423 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 62 7e-09
CE23923 [O] KOG1864 Ubiquitin-specific protease 62 7e-09
CE23922 [O] KOG1864 Ubiquitin-specific protease 62 7e-09
At5g06600 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 62 7e-09
Hs22043041 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 61 1e-08
Hs20532433 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 61 1e-08
7295436 [O] KOG4598 Putative ubiquitin-specific protease 61 1e-08
7293523 [Z] KOG2026 Spindle pole body protein - Sad1p 61 1e-08
Hs4759296 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 60 2e-08
YKR098c [O] KOG1868 Ubiquitin C-terminal hydrolase 60 3e-08
CE20660 [Z] KOG2026 Spindle pole body protein - Sad1p 60 3e-08
Hs22045513 [O] KOG1868 Ubiquitin C-terminal hydrolase 59 4e-08
Hs22067085 [O] KOG1871 Ubiquitin-specific protease 57 2e-07
7292738 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 57 2e-07
YBL067c [O] KOG1864 Ubiquitin-specific protease 57 2e-07
CE13299 [O] KOG4598 Putative ubiquitin-specific protease 57 2e-07
Hs22044589 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 56 4e-07
Hs13994268 [O] KOG1868 Ubiquitin C-terminal hydrolase 55 5e-07
SPBP8B7.21 [O] KOG1871 Ubiquitin-specific protease 55 7e-07
Hs22047539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 55 7e-07
Hs20483065 [O] KOG1864 Ubiquitin-specific protease 55 7e-07
7292313 [O] KOG0944 Ubiquitin-specific protease UBP14 54 2e-06
YMR304w [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 53 3e-06
7292013_2 [O] KOG1871 Ubiquitin-specific protease 53 3e-06
7303452 [O] KOG1864 Ubiquitin-specific protease 53 3e-06
Hs4507857 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 52 5e-06
At4g22350 [Z] KOG2026 Spindle pole body protein - Sad1p 52 5e-06
>YJL197w [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1254
Score = 853 bits (2203), Expect = 0.0
Identities = 477/1151 (41%), Positives = 668/1151 (57%), Gaps = 68/1151 (5%)
Query: 72 IQDQRSIVANMWVRFNNEKKEGDLVFIIPERWLALFQDPNIIDYRSIPSIDVASISLDYK 131
++ QR +VA + +KEGD V I+P+ W F DP++ D I I+ I D++
Sbjct: 99 LEQQRDVVARLIEENKETQKEGDKVCIVPKVWYDKFFDPDVTDPEDIGPINTRMICRDFE 158
Query: 132 NFILQDYTQHLYTAVPASMFTLLQQWYDLTPNSKPIST-FIVRDANNQLLVEYDRPRCRI 190
NF+L+DY + Y ++ +F L + Y +T S P+ T ++ +L EY++ R+
Sbjct: 159 NFVLEDYNRCPYLSIAEPVFNFLSEIYGMTSGSYPVVTNLVINQTTGELETEYNKWFFRL 218
Query: 191 HHLVAGNGNANIYPGSSRHSIDHKIPLMFTMSRLATMKDVIQRCLEVFYAKEPHLDKSSL 250
H+L RH D I + +MS L ++D++++ + +F+ K HLD +++
Sbjct: 219 HYLTEKQDGRK-----RRHGQDDSI-MYLSMSALNLVRDLVEKSMNLFFEKADHLDVNAV 272
Query: 251 THRIWYINER--VADPKSTQTLL-SNYVLSPSAFLELQTKHEITKSMYSRQLKDYDSQII 307
+IW+++E +A + T L S+Y ++P FLEL K + M+ +L S
Sbjct: 273 DFKIWFVSEGSDIATDSNVSTFLNSSYEITPLQFLELPIKKLLIPDMFENRLDKITSNPS 332
Query: 308 SLVVEVKQKSSNQHWPSNFFHYNKLNAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYF 367
LV+E+K N HWPSN+F YNKL SG GL NLGNTCYMNSALQCL+HIP+L +YF
Sbjct: 333 DLVIEIKPIEGNHHWPSNYFAYNKLEPASGTTGLVNLGNTCYMNSALQCLVHIPQLRDYF 392
Query: 368 LYKGYEREININNPLGHKGDVAHAFGHLLYSLFAPSYG---QSTFYAPRNFKNTIGHYNS 424
LY GYE EIN NPLG+ G VA AF L+ LF ++ + P FK+TIGH+NS
Sbjct: 393 LYDGYEDEINEENPLGYHGYVARAFSDLVQKLFQNRMSIMQRNAAFPPSMFKSTIGHFNS 452
Query: 425 LFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWD 484
+F+GY QQDSQEFLAFLLD LHEDLNR+I+K Y KP ++D + + LA + W+
Sbjct: 453 MFSGYMQQDSQEFLAFLLDSLHEDLNRIIKKEYTEKPSLSPGDDVNDWNVVKKLADDTWE 512
Query: 485 YIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLPIENYWSTKVTIFPQN 544
KRN SVI DLFVG+YKSTL CP C +VSITFDPYND+TLPLP++ W + IFP N
Sbjct: 513 MHLKRNCSVITDLFVGMYKSTLYCPECQNVSITFDPYNDVTLPLPVDTVWDKTIKIFPMN 572
Query: 545 SPPCTLEVELSKTSSYNDLKAYVAQHANMHANDLIGAEIFNHQFYNNYESNVE-ADYLPI 603
SPP LEVELSK+S+Y DLK YV + + + N L G EIF++Q Y NYES A +L +
Sbjct: 573 SPPLLLEVELSKSSTYMDLKNYVGKMSGLDPNTLFGCEIFSNQIYVNYESTESNAQFLTL 632
Query: 604 SELISESDTVIFYEVHRGQD-DLVVPILNTRFEEGFKTPRLFGYPFFIALSQAEQFSYGA 662
ELI +D VIFYE+ D +++VP+LNTR E+G+K LFG PFFI L + E + GA
Sbjct: 633 QELIKPADDVIFYELPVTNDNEVIVPVLNTRIEKGYKNAMLFGVPFFITLKEDELNNPGA 692
Query: 663 IRKKIEKCYQNFSGGFSEFPIVGKTKMPDLSSMPLLEKRYSQCEIESIMPELEYINPEMS 722
IR K++ + + SGG+ FP + + PLL ++Y E E L+Y + +++
Sbjct: 693 IRMKLQNRFVHLSGGYIPFPEPVGNRTDFADAFPLLVEKYPDVEFEQYKDILQYTSIKVT 752
Query: 723 VDE--FFQLKILKVDS---VSSNRRV-----TSFSGVSLGQTSDEPNSQIWIPPTASLIT 772
+ FF +KIL V+ +SN R T S ++L + +D + +
Sbjct: 753 DKDKSFFSIKILSVEKEQQFASNNRTGPNFWTPISQLNLDKATDIDDKLEDVVKDI---- 808
Query: 773 YNHSELIRKALPEAIEA----------AYYYSDMLSNEDDIPNDQTVSDTAN-------- 814
YN+S L+ A ++ A +S + DD N +TV++ N
Sbjct: 809 YNYSSLVDCAEGVLMQVDDEGDTEGSEAKNFSKPFQSGDDEENKETVTNNENVNNTNDRD 868
Query: 815 ---DLATKSYTSPNPEENVTSSAEALD---GTLHLKVSPLLDVHNAIICEWEAVKVINVF 868
+L + E +T EALD +L +L +++ I+CEW + F
Sbjct: 869 EDMELTDDVEEDASTEPELTDKPEALDKIKDSLTSTPFAILSMNDIIVCEWSELGSNEAF 928
Query: 869 DEDNGVNWDHPAILENLSLSEVRKTRAQTEKSSITLDSCLRLFSQPEILGSADSWYCPNC 928
+D NW++PA L N L + R+ ++ +ITLD CL+LFS+PEILG DSWYCP C
Sbjct: 929 SDDKIYNWENPATLPNKELENAKLERSNAKERTITLDDCLQLFSKPEILGLTDSWYCPTC 988
Query: 929 KQHTQASKQIELWNTPDILLIHLKRFENQRSFSDKIDATVKFPIEGLDMSPYLSYKKEGE 988
K+H QA+KQI+LWNTPDILLIHLKRFE+QRSFSDKIDATV FPI LD+S Y+ YK +
Sbjct: 989 KEHRQATKQIQLWNTPDILLIHLKRFESQRSFSDKIDATVNFPITDLDLSRYVVYKDDPR 1048
Query: 989 NDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYR 1048
+YDL AVDNHYGGLGGGHYTAY +NF D KWYYFDDSRV E +PENSIAGSAYLLFY
Sbjct: 1049 GLIYDLYAVDNHYGGLGGGHYTAYVKNFADNKWYYFDDSRVTETAPENSIAGSAYLLFYI 1108
Query: 1049 RRTSGNQTLGNGKLRDIIDISRKEYEQKQDEFMTNVETLYAATHTDTESEASDSDRSSVD 1108
RR LG+ KL++II SR Y+++ + LY TD E + SD D +
Sbjct: 1109 RRHKDGNGLGSSKLQEIIQKSRHGYDERIKKIYDEQMKLYEFNKTDEEEDVSD-DMIECN 1167
Query: 1109 EEMDS-------------DNSDCENDKKSAFVDQSDISSNSLGMDNLTYSNRPSKDNTIH 1155
E++ + + DC ++ + ++++ L + Y N ++
Sbjct: 1168 EDVQAPEYSNRSLEVGHIETQDCNDEDDNDDGERTNSGRRKLRLLKKVYKNNSGLGSS-S 1226
Query: 1156 TSKNANGSIES 1166
TS+ + G E+
Sbjct: 1227 TSEISEGCPEN 1237
>SPCC1494.05c [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 979
Score = 460 bits (1184), Expect = e-129
Identities = 357/1088 (32%), Positives = 526/1088 (47%), Gaps = 160/1088 (14%)
Query: 12 SECLKYSLHGTPSEGINLEQLISGSNADGIISTSSIEENPTDXXXXXXXXXXXXYDAIPP 71
SE S HG ++ E+ S SN D I S + ++ +P
Sbjct: 5 SESSTSSYHGKRPRSLS-EESQSSSNMDDISQKSISLGDASEISKN-----------LPS 52
Query: 72 IQDQRSIVANMWVRFNNEKKEGDLV-FIIPERWLA-----LFQD---PNIIDYRSIPSID 122
I +Q+ ++ + V E + G + +I+ W L +D P +D I ++
Sbjct: 53 IAEQKQLIGEL-VNNQPELELGQVDNYILSYSWYERLCSYLAEDGPFPGPVDQEDIADLE 111
Query: 123 VASISLDYKNFILQDYTQHLYTAVPASMFTLLQQWYDLTPNSKPISTF-IVRDANNQLLV 181
++ D + I +T + ++ LL +WY L P T + +++ L+V
Sbjct: 112 TGTLKPDLQEEID-------FTIISRDVWDLLVRWYGLKGPEFPRETVNLGSESHPHLVV 164
Query: 182 EYDRPRCRIHHLVAGNGNANIYPGSSRHSIDHKIPLMFTMSRLATMKDVIQRCLEVFYAK 241
E P + L +AN HK P ++S +T++D+++ V Y
Sbjct: 165 EVYPPIFSLTLLSTNAVDANE---------SHK-PKKISLSSKSTLEDLLEG---VKYT- 210
Query: 242 EPHLDKSSLTHRIWYINERVADPKSTQTLLSNYVLSPSAFLELQTKHEITKSMYSRQLKD 301
L S R+W ++ + Q L + + PS+F+++ +K I S+ L +
Sbjct: 211 ---LSLPSDQFRLWRVD-------TDQPL--HRTIDPSSFIKINSKEIIDFLEKSKTLVE 258
Query: 302 YD-SQIISLVVEVKQKSSNQHWPSN------FFHYNKLNAPS-----------GIMGLSN 343
SLV E N+ WP + F + N S G GLSN
Sbjct: 259 LGMDSSCSLVAECM---INETWPVDRALRLQFLIQQRNNQSSNEEQKQEKRVPGTCGLSN 315
Query: 344 LGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLLYSLFAPS 403
LGNTCYMNSALQCL H EL ++F ++ ++N +NPLG G VA F L+ SL++P
Sbjct: 316 LGNTCYMNSALQCLTHTRELRDFFTSDEWKNQVNESNPLGMGGQVASIFASLIKSLYSPE 375
Query: 404 YGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYVNKPEF 463
+ +APR FK TIG +N F GYGQQDSQEFLAFLLDGLHEDLNR+ +KPY +KP+
Sbjct: 376 HSS---FAPRQFKATIGKFNHSFLGYGQQDSQEFLAFLLDGLHEDLNRIYQKPYTSKPDL 432
Query: 464 PNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYND 523
D ++I A W K RNDS+I+DLF G+Y+STLVCP CN VSITFDP+ D
Sbjct: 433 YEV----DEEKIKNTAEECWRLHKLRNDSLIVDLFQGMYRSTLVCPVCNTVSITFDPFMD 488
Query: 524 LTLPLPIENYWSTKVTIFP--QNSPPCTLEVEL-SKTSSYNDLKAYVAQHAN-MHANDLI 579
LTLPLP++ WS VT P N P +EV L SK ++ DL YVA+ + ++
Sbjct: 489 LTLPLPVKQVWSHTVTFIPADTNLTPLAIEVVLESKAATIEDLVKYVAEKSGCSDYRKIL 548
Query: 580 GAEIFNHQFYNNYESNVEADYLPISELISESDTVIFYEVHR----GQDDLVVPIL----- 630
E + +FY + + + L ISE D + YE+ R G DD++VP+
Sbjct: 549 VTETYKGRFY-RFLTQLSKSLL---MEISEEDEIYLYELERPYEDGSDDILVPVYHISDD 604
Query: 631 NTRFEEGFKTPRLFGYPFFIALSQAEQFSYGAIRKKIEKCYQNFSGGFSEFPIVGKTKMP 690
+T + + R FG+PF + LS E I +K++ YQ F T +
Sbjct: 605 STNSANSYMSSRDFGHPFVLQLSDNEVTDASFISEKLKLKYQQF------------TTLK 652
Query: 691 DLSSMPLLEKRYSQCEIESIMPELEYINPEMSVDEFFQLKILKVDSVSSNRRVTSFSGVS 750
+L ++ LE E E + ++ + S F++++ F +
Sbjct: 653 NLKNIDSLESLELGHEDEQVQKGPLDVDMDHSQTPLFEMRVFH----------DRFEKIP 702
Query: 751 LGQTSDEPNSQIWIPPTASLITYNHSELIRKALPEAIEAAYYYSDMLSNEDDIPNDQTVS 810
G N + +E +K L ++ +S + EDD
Sbjct: 703 TGWNMSVSNLPLL------------TERDKKDLESTVDPLDAHS--IEEEDD-------- 740
Query: 811 DTANDLATKSYTSPN-PEENVTSSAEALDGTLHLKVSPLLDVHNAIICEWEAVKVINVFD 869
D+A SY P+ EN +A+ D LL + ++CEW VF
Sbjct: 741 SEFKDVAPGSYPEPSKSNENTKLTAKEND--------RLLIQGDLLVCEWPEKSYQFVFS 792
Query: 870 -EDNGVNWDHPAILENLSLSEVRKTRAQTEKSSITLDSCLRLFSQPEILGSADSWYCPNC 928
+ LE+ ++ +K ++ + +ITL+ CL F + E LG D WYCP C
Sbjct: 793 VAPSSPQMGRSLWLESKTILSDKKDDSE-DSRTITLNDCLDEFEKTEQLGEEDPWYCPTC 851
Query: 929 KQHTQASKQIELWNTPDILLIHLKRFENQRSFSDKIDATVKFPIEGLDMS----PYLSYK 984
K+ QASKQ+E+W P+IL+ HLKRF ++R F DKID V+FPI+ LDMS Y +
Sbjct: 852 KEFRQASKQMEIWRCPEILIFHLKRFSSERRFRDKIDDLVEFPIDNLDMSMRTGSYKLSE 911
Query: 985 KEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYL 1044
KE +Y+L AVDNHYGGLGGGHYTA+ +N +G++Y FDDSRV V PE ++ +AYL
Sbjct: 912 KENPKLIYELYAVDNHYGGLGGGHYTAFAKNPDNGQFYCFDDSRVTPVCPEETVTSAAYL 971
Query: 1045 LFYRRRTS 1052
LFYRR+TS
Sbjct: 972 LFYRRKTS 979
>SPCC16A11.12c [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 849
Score = 230 bits (587), Expect = 9e-60
Identities = 183/623 (29%), Positives = 296/623 (47%), Gaps = 53/623 (8%)
Query: 71 PIQDQRSIVANMWVRFNNEKKEGDLVFIIPERWLALFQDPNIIDYRSIPSIDVASISLDY 130
P QD +++ ++ EK F+I W + D I P LD
Sbjct: 25 PFQDSINLIKEDKEKWKKEKT----AFLIDYDWFEGYVD-FIYGEGDNPGPITQWRLLDE 79
Query: 131 KNFILQDYTQHL-YTAVPASMFTLLQQWYDLTPNSKPISTFIVRDANNQLLVEYDRPRCR 189
KN + + + Y+ V AS++ +L +W+ L + +V A Q P
Sbjct: 80 KNELKHSLEESIDYSIVSASLWHMLVEWFGLEGLAIERKVLLVGLAAEQKPFVDIYPINF 139
Query: 190 IHHLVAGNGNANIYPGSSRHSIDHKI----PLMFTMSRLATMKDVIQRCLEVFYAKEPHL 245
H++ N S + ID P F+ SR T++ + ++ +E F +
Sbjct: 140 TLHVLFDPINGENTSYSPLYQIDEPYHSDEPYAFSFSRSDTLRSLYKQVMEAFQISD--- 196
Query: 246 DKSSLTHRIWYINERVADPKSTQTLLSNYVLSPSAFLELQTKHEITKSMYSRQLKDYDSQ 305
+ R+WY+N+ ++ S LS + P+ + L +++ + +++ + D
Sbjct: 197 ---GTSFRLWYLNK--SNLSSRFVSLSEFNDQPA--IALLSEYAVCMTIFEIDIADG--- 246
Query: 306 IISLVVEVKQKSSNQHWPSNFFHYNK---LNAPSGIMGLSNLGNTCYMNSALQCLLHIPE 362
SL++E + N W S+ + +N G+ GL NLGN+CYMNSALQC++H E
Sbjct: 247 --SLLLEFQHP--NGEWLSDSITKEQNLTINKEIGLCGLYNLGNSCYMNSALQCMIHTHE 302
Query: 363 LNEYFLYKGYEREININNPLGHKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHY 422
L +YFL YE++IN NNPLG G VA ++ LL + + S +P +FK IG +
Sbjct: 303 LTKYFLSDSYEKDINYNNPLGMMGKVALSYASLLKMIHHTADMHSV--SPSSFKFIIGEF 360
Query: 423 NSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYVNKPEFPNDGQIDDTDQIVLLAANM 482
N+ F+GY QQDSQEF+AF LDGLHEDLNR+ KPY +P+ ++ + + +A
Sbjct: 361 NTYFSGYRQQDSQEFIAFFLDGLHEDLNRIQIKPYFERPDLFDEHPL----HVQRVANQC 416
Query: 483 WDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLPIENYWSTKVTIFP 542
WD KRNDS+I+ LF G+YKSTL C C S FDP+ LTLPLP W KV P
Sbjct: 417 WDIHTKRNDSIIVQLFQGMYKSTLECSICYQKSTAFDPFMYLTLPLPTSAKWRHKVVYVP 476
Query: 543 Q--NSPPCTLEVELSKTSSYNDLKAYVA---QHANMHANDLIGAEIFNHQFYNNYESNVE 597
P L +EL S+ +K Q + +L +I+ + Y ++ +
Sbjct: 477 PFGTQSPVELYLELLMESTVIQMKFQATEKLQKMGLECGELTACDIYRGKVYKVLKNKDK 536
Query: 598 ADYLPISELISESDTVIFYEVHRGQDDLVVPILN----TRFEEGFKTPRLFGYPFFIALS 653
IS+ I + D V+ Y + L +PI++ +++ +FG+P + +
Sbjct: 537 -----ISKKIHKWDHVVLY--GSTANGLTIPIVHGCKRPAMPGSYQSNDVFGFPLQLNVR 589
Query: 654 QAEQFSYGAIRKKIEKCYQNFSG 676
+ + K+I + Y+ ++G
Sbjct: 590 SRNVLTNDLV-KEIVELYRVYAG 611
Score = 131 bits (330), Expect = 6e-30
Identities = 68/168 (40%), Positives = 98/168 (57%), Gaps = 12/168 (7%)
Query: 894 RAQTEKSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKR 953
+ Q SITL+ CL FS+PE L DSWYCP CK A+K++E+W P IL+IHL R
Sbjct: 682 KIQFHMESITLEDCLLEFSKPEQLDLQDSWYCPGCKAFRPATKRLEIWRLPKILVIHLNR 741
Query: 954 FENQ----RSFSDKIDATVKFPIEGLDMSPYLS-------YKKEGENDVYDLIAVDNHYG 1002
F R + D V +P+ L++ +LS + ++ +YDL AVDNH+G
Sbjct: 742 FSGHGGDLRRRRKRRDLVV-YPVFDLNLKQFLSPFIKDHEWLSSQKSMLYDLYAVDNHHG 800
Query: 1003 GLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRR 1050
+ GHYTAY R+ ++ FDD+ + E+ PE+ + SAY+LFYR +
Sbjct: 801 FMSNGHYTAYARDASSQTFFKFDDTAICEIDPEDIVTSSAYVLFYRAK 848
>Hs4759290 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 690
Score = 228 bits (582), Expect = 4e-59
Identities = 139/366 (37%), Positives = 202/366 (54%), Gaps = 42/366 (11%)
Query: 311 VEVKQKSSNQHWPSNFFHYNKLNAPS---------GIMGLSNLGNTCYMNSALQCLLHIP 361
+E ++K WPS H N GI GL+NLGNTC+MNSALQCL ++P
Sbjct: 1 METRKKDGT--WPSAQLHVMNNNMSEEDEDFKGQPGICGLTNLGNTCFMNSALQCLSNVP 58
Query: 362 ELNEYFLYKGYEREININNPLGHKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGH 421
+L EYFL Y E+N NPLG KG++A A+ L+ ++ G P FKN +GH
Sbjct: 59 QLTEYFLNNCYLEELNFRNPLGMKGEIAEAYADLVKQAWS---GHHRSIVPHVFKNKVGH 115
Query: 422 YNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYVNKPEFPNDGQIDDTDQIVLLAAN 481
+ S F GY Q DSQE L+FLLDGLHEDLNRV +K YV + G+ D +A
Sbjct: 116 FASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAA--GRPDQE-----VAQE 168
Query: 482 MWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLPIENYWSTKVTIF 541
W K+RNDSVI+D F GL+KSTLVCP+C +VS+TFDP+ L++PLPI + +V
Sbjct: 169 AWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPISHKRVLEVFFI 228
Query: 542 PQN--SPPCTLEVELSKTSSYNDLKAYVAQHANMHANDLIGAEIFNHQFYNNYESNVEAD 599
P + P + + K +DL +++H + ++ A++F+H+FY Y+
Sbjct: 229 PMDPRRKPEQHRLVVPKKGKISDLCVALSKHTGISPERMMVADVFSHRFYKLYQLEE--- 285
Query: 600 YLPISELISESDTVIFYEV-------HRGQDDLVVPI-LNTR-----FEEGFKTPRLFGY 646
P+S ++ + D + YEV ++D+VVP+ L R + + LFG+
Sbjct: 286 --PLSSIL-DRDDIFVYEVSGRIEAIEGSREDIVVPVYLRERTPARDYNNSYYGLMLFGH 342
Query: 647 PFFIAL 652
P +++
Sbjct: 343 PLLVSV 348
Score = 149 bits (375), Expect = 4e-35
Identities = 69/163 (42%), Positives = 102/163 (62%), Gaps = 3/163 (1%)
Query: 898 EKSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQ 957
+K+ + L C+ LF+ E L + WYCP+CKQH A+K+++LW P+IL+IHLKRF
Sbjct: 502 KKAPVRLQECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWMLPEILIIHLKRFSYT 561
Query: 958 RSFSDKIDATVKFPIEGLDMSPYLSYKKEGEND---VYDLIAVDNHYGGLGGGHYTAYCR 1014
+ +K+D V+FPI LD S ++ + N YDLIAV NHYGG+ GHYT +
Sbjct: 562 KFSREKLDTLVEFPIRDLDFSEFVIQPQNESNPELYKYDLIAVSNHYGGMRDGHYTTFAC 621
Query: 1015 NFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRRTSGNQTL 1057
N G+W+YFDD+ V+ V+ + +AY+LFY+R+ + L
Sbjct: 622 NKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVARRLL 664
>Hs14149627 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 952
Score = 228 bits (580), Expect = 6e-59
Identities = 172/605 (28%), Positives = 297/605 (48%), Gaps = 69/605 (11%)
Query: 72 IQDQRSIVANMWVRFNNEKKEGDLVFIIPERWLALFQDP---NIIDYRSIPSIDVASISL 128
+ QRS +A + ++GD +++ RW ++ + D + +V +
Sbjct: 9 LDTQRSDIATL---LKTSLRKGDTWYLVDSRWFKQWKKYVGFDSWDKYQMGDQNVYPGPI 65
Query: 129 DYKNFI----LQDYTQHL-----YTAVPASMFTLLQQWYDLTPNSKPISTFIVRDANNQL 179
D + Q +HL Y +P + L WY L +PI+ +V +
Sbjct: 66 DNSGLLKDGDAQSLKEHLIDELDYILLPTEGWNKLVSWYTLMEGQEPIARKVVEQG---M 122
Query: 180 LVEYDRPRCRIHHL-VAGNGNANIYPGSSRHSIDHKIPLMFTMS-RLATMKDVIQRCLEV 237
V++ + + L + NGN N + + F+ + + T++ I++ +
Sbjct: 123 FVKHCKVEVYLTELKLCENGNMN-----------NVVTRRFSKADTIDTIEKEIRKIFSI 171
Query: 238 FYAKEPHLDKSSLTHRIWYINERVADPKSTQTLLSNYVLSPSAFLELQTKHEITKSMYSR 297
KE L +++ +N+ P ST + + L L ++ K+E
Sbjct: 172 PDEKETRLWNKYMSNTFEPLNK----PDST---IQDAGLYQGQVLVIEQKNEDGTWPRGP 224
Query: 298 QLKDYDSQIISLVVEVKQKSSNQHWPSNFFHYNKLNAPSGIMGLSNLGNTCYMNSALQCL 357
+ + L K+ + P + N G+ GLSNLGNTC+MNSA+QCL
Sbjct: 225 STPNVKNSNYCLPSYTAYKNYDYSEPG------RNNEQPGLCGLSNLGNTCFMNSAIQCL 278
Query: 358 LHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKN 417
+ P L EYFL Y+ E+N +NPLG +G++A ++ L+ +++ G+ ++ PR FK
Sbjct: 279 SNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELIKQMWS---GKFSYVTPRAFKT 335
Query: 418 TIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYVNKPEFPNDGQIDDTDQIVL 477
+G + F+GY QQD QE LAFLLDGLHEDLNR+ +KPY+ + DG+ D +
Sbjct: 336 QVGRFAPQFSGYQQQDCQELLAFLLDGLHEDLNRIRKKPYIQLKD--ADGRPDK-----V 388
Query: 478 LAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLPIENYWSTK 537
+A W+ KRNDS+I+D+F GL+KSTLVCP C +S+TFDP+ LTLPLP++ + +
Sbjct: 389 VAEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYLTLPLPMKKERTLE 448
Query: 538 VTIFPQN--SPPCTLEVELSKTSSYNDLKAYVAQHANMHANDLIGAEIFNHQFYNNYESN 595
V + + + P +V + K + DL ++ + + A+ +I +I+NH+F+ + +
Sbjct: 449 VYLVRMDPLTKPMQYKVVVPKIGNILDLCTALSALSGIPADKMIVTDIYNHRFHRIFAMD 508
Query: 596 VEADYLPISELISESDTVIF-YEVHRGQD--DLVVPI-LNTRFEEGFKT----PRLFGYP 647
+S ++ D +F ++R +D +++P+ L +F T LFG P
Sbjct: 509 EN-----LSSIMERDDIYVFEININRTEDTEHVIIPVCLREKFRHSSYTHHTGSSLFGQP 563
Query: 648 FFIAL 652
F +A+
Sbjct: 564 FLMAV 568
Score = 180 bits (456), Expect = 1e-44
Identities = 111/331 (33%), Positives = 162/331 (48%), Gaps = 42/331 (12%)
Query: 795 DMLSNEDDIPNDQTVSDTANDLAT----KSYTSPNPEENVTSSAEALDGTLHLKVSPL-- 848
D + ++D N DT T + +T T D T H++
Sbjct: 653 DSVGGDNDSENGLCTEDTCKGQLTGHKKRLFTFQFNNLGNTDINYIKDDTRHIRFDDRQL 712
Query: 849 -LDVHNAIICEWEAVKVINVFDEDNGVNWDHPAILENLSLSEVRKTRAQTEKSSITLDSC 907
LD + + +W+ FDE+ +++ +E +K + L C
Sbjct: 713 RLDERSFLALDWDPDLKKRYFDENAAEDFEKHESVEY----------KPPKKPFVKLKDC 762
Query: 908 LRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSDKIDAT 967
+ LF+ E LG+ D WYCPNCK+H QA+K+++LW+ P +L++HLKRF R DK+D
Sbjct: 763 IELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSRYMRDKLDTL 822
Query: 968 VKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDS 1027
V FPI LDMS +L G Y+LIAV NHYGG+GGGHYTA+ +N DGKWYYFDDS
Sbjct: 823 VDFPINDLDMSEFLINPNAGPCR-YNLIAVSNHYGGMGGGHYTAFAKNKDDGKWYYFDDS 881
Query: 1028 RVNEVSPENSIAGSAYLLFYRRRTSGNQTLGNGKLRDIIDISRKEYEQKQDEFMTNVETL 1087
V+ S + ++ +AY+LFY+R+ + + T F + ET
Sbjct: 882 SVSTASEDQIVSKAAYVLFYQRQDTFSGT---------------------GFFPLDRETK 920
Query: 1088 YAATHTDTESEASDSDRSSVDEEMDSDNSDC 1118
A+ T E SD S D + D +N +C
Sbjct: 921 GASAATGIPLE---SDEDSNDNDNDIENENC 948
>At1g32850 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 887
Score = 225 bits (574), Expect = 3e-58
Identities = 136/318 (42%), Positives = 190/318 (58%), Gaps = 23/318 (7%)
Query: 337 GIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLL 396
G+ GL NLGNTC+MNS LQCL H P + EYFL + Y +IN NPLG +G++A AFG LL
Sbjct: 294 GLGGLQNLGNTCFMNSTLQCLAHTPPIVEYFL-QDYRSDINAKNPLGMRGELAIAFGELL 352
Query: 397 YSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKP 456
L+ S GQ+T APR FK + + F+GY Q DSQE LAFLLDGLHEDLN+V KP
Sbjct: 353 RKLW--SSGQNTV-APRAFKTKLARFAPQFSGYNQHDSQEMLAFLLDGLHEDLNKVKRKP 409
Query: 457 YVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSI 516
Y+ + +DG+ DD +A W Y K RNDSVI+D+F G YKSTLVCP+C +SI
Sbjct: 410 YIEAKD--SDGRPDDE-----VAEEKWKYHKARNDSVIVDVFQGQYKSTLVCPDCGKISI 462
Query: 517 TFDPYNDLTLPLPIENYWSTKVTIFPQNSP--PCTLEVELSKTSSYNDLKAYVAQHANMH 574
TFDP+ L+LPLP S VT+F + P V + K S DL + +
Sbjct: 463 TFDPFMYLSLPLPSSRTRSMTVTVFYGDGSHLPMPYTVTVPKDGSCRDLSNALGTACCLD 522
Query: 575 AND-LIGAEIFNHQFYNNYESNVEADYLPISELISESDTVIFY---EVHRGQDDLVVPIL 630
++ L+ AE+++H+ + YE+ E + I +++ ++ Y ++H+G + + IL
Sbjct: 523 NDESLLLAEVYDHKVFKYYENPRE-----LLNGIKDNEHIVAYRFKQMHKGPGKVKLEIL 577
Query: 631 NTRFEEGF-KTPRLFGYP 647
+ E+ + P+ FG P
Sbjct: 578 HGEQEKSSDRGPKCFGTP 595
Score = 172 bits (435), Expect = 4e-42
Identities = 92/236 (38%), Positives = 134/236 (55%), Gaps = 11/236 (4%)
Query: 830 VTSSAEALDGTLHLKVSPLLDVHN---------AIICEWEAVKVINVFDEDNGVNWDHPA 880
++ E D L +S L D ++ +++ KV+ ++E +D +
Sbjct: 648 LSRDTETEDNDRELSLSLLRDYYSFNLQPLESDSVVNPGSVTKVLVKWNEKEHEKYDS-S 706
Query: 881 ILENLSLSEVRKTRAQTEKSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIEL 940
L +L +T + I+L SCL F E LG D WYCP CK+H QA+K+++L
Sbjct: 707 YLNDLPKVHKNVLAKKTMQEGISLFSCLEAFLAEEPLGPDDMWYCPGCKEHRQANKKLDL 766
Query: 941 WNTPDILLIHLKRFENQRSFSDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNH 1000
W PDIL+ HLKRF R F +KID V F I LD+S Y+ ++G++ +Y+L A+ NH
Sbjct: 767 WKLPDILVFHLKRFTYSRYFKNKIDTLVNFHIHDLDLSKYVK-NEDGQSYLYELYAISNH 825
Query: 1001 YGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRRTSGNQT 1056
YGGLGGGHYTAY + + KWY FDDSRV+ V+ +AY+LFY+R S ++T
Sbjct: 826 YGGLGGGHYTAYAKLMDETKWYNFDDSRVSAVNESEIKTSAAYVLFYQRVKSDSET 881
>Hs4507853 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 963
Score = 215 bits (548), Expect = 3e-55
Identities = 128/339 (37%), Positives = 193/339 (56%), Gaps = 31/339 (9%)
Query: 329 YNKLNAPS-----GIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLG 383
YN PS G+ GL NLGNTC+MNSALQCL + L +YFL YE EIN +NPLG
Sbjct: 287 YNCQEPPSSHIQPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLG 346
Query: 384 HKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLD 443
KG++A A+ L+ +++ G+ AP FK +G + F+GY QQDSQE LAFLLD
Sbjct: 347 MKGEIAEAYAELIKQMWS---GRDAHVAPSMFKTQVGRFAPQFSGYQQQDSQELLAFLLD 403
Query: 444 GLHEDLNRVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYK 503
GLHEDLNRV +KPY+ + +G+ D ++A W+ + RNDSVI+D F GL+K
Sbjct: 404 GLHEDLNRVKKKPYLELKD--ANGRPD-----AVVAKEAWENHRLRNDSVIVDTFHGLFK 456
Query: 504 STLVCPNCNHVSITFDPYNDLTLPLPIENYWSTKVTIFP--QNSPPCTLEVELSKTSSYN 561
STLVCP C VS+TFDP+ LTLPLP++ +V + P + P V + + +
Sbjct: 457 STLVCPECAKVSVTFDPFCYLTLPLPLKKDRVMEVFLVPADPHCRPTQYRVTVPLMGAVS 516
Query: 562 DLKAYVAQHANMHANDLIGAEIFNHQFYNNYESNVEADYLPISELISESDTVIFYEVHR- 620
DL +++ + + A +++ A+++NH+F+ ++ + ++ I D + YEV
Sbjct: 517 DLCEALSRLSGIAAENMVVADVYNHRFHKIFQMDEGLNH------IMPRDDIFVYEVCST 570
Query: 621 ---GQDDLVVPIL----NTRFEEGFKTPRLFGYPFFIAL 652
G + + +P+ +R L+G P +++
Sbjct: 571 SVDGSECVTLPVYFRERKSRPSSTSSASALYGQPLLLSV 609
Score = 180 bits (456), Expect = 1e-44
Identities = 96/262 (36%), Positives = 146/262 (55%), Gaps = 16/262 (6%)
Query: 795 DMLSNEDDIPNDQTVSDTANDLATKSYTSPNPEENVTSSAEALDGTLHLKVSPL------ 848
+ LS + D+ +D + K P P+ T S GT +
Sbjct: 672 EQLSETEGSGEDEPGNDPSETTQKKIKGQPCPKRLFTFSLVNSYGTADINSLAADGKLLK 731
Query: 849 LDVHNAIICEWEAVKVINVFDEDNGVNWDHPAILENLSLSEVRKTRAQTEKSSITLDSCL 908
L+ + + +W+ +DE ++ +++S+ + +K + K+++ L C+
Sbjct: 732 LNSRSTLAMDWDRETRRLYYDEQESEAYE-----KHVSMLQPQKKK----KTTVALRDCI 782
Query: 909 RLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSDKIDATV 968
LF+ E LG D WYCPNCK+H QA+K+ +LW+ P IL++HLKRF R + DK+D V
Sbjct: 783 ELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDKLDTVV 842
Query: 969 KFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSR 1028
+FPI GL+MS ++ VYDLIAV NHYG +G GHYTAY +N ++GKWYYFDDS
Sbjct: 843 EFPIRGLNMSEFVC-NLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNKLNGKWYYFDDSN 901
Query: 1029 VNEVSPENSIAGSAYLLFYRRR 1050
V+ S + + +AY+LFY+RR
Sbjct: 902 VSLASEDQIVTKAAYVLFYQRR 923
>At4g10590 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 937
Score = 209 bits (531), Expect = 3e-53
Identities = 197/643 (30%), Positives = 304/643 (46%), Gaps = 96/643 (14%)
Query: 73 QDQRSIVANMWVRFNNEKKEGDLVFIIPERWLALFQ---DPNIIDYRS-----------I 118
++++ IV+ + + KEG+L F+I +RW ++ + + +Y S I
Sbjct: 22 EEEKRIVSELITESEDNLKEGNLYFVISKRWYTSWEKYVEQSTKEYISGESSEASRPGPI 81
Query: 119 PSIDVASISLDYKNFILQDYTQHL--YTAVPASMFTLLQQWYDLTPNSKPISTFIVRDA- 175
+ D+ D + L+ Y VP ++ L +WY P PI ++
Sbjct: 82 DNHDIIESESDVNDPQLRRLLMERVDYVLVPQEVWKRLVEWYSGGP---PIERKLICQGF 138
Query: 176 -NNQLLVEYDRPRCRIHHLVAGNGNAN----IYPGSSRHSIDHKIPLM--FTMSRLATMK 228
VE P C + L G + + +S + K+ + + MK
Sbjct: 139 YTRSYSVEV-YPLCLM--LTDGRDESRTVIRLGKQASIRELYEKVCALTGVPQEKFLLMK 195
Query: 229 DVIQRCLEVFYAKEPHLDKSSLTH-RIW-YINER---VADPKSTQTLL-SNYVLSPSAFL 282
D + R + +A PH+D IW Y ++R + D S ++L S+ + L
Sbjct: 196 DALFRYED--FAALPHIDIFFYKQAHIWDYFDKRKNGLLDSLSYKSLEESSLHMDQDILL 253
Query: 283 ELQTKHEITKSMYSR----QLKDYDSQIISLVVEVKQKSSNQH-WPSNFFHYNKLNAPS- 336
E+ +M S L + S+ + SN H SNF + ++ +
Sbjct: 254 EVDGSSSSQSAMSSTGNELALVPLEPSRSSVTIAGGPTLSNGHSTTSNFSLFPRITSEDD 313
Query: 337 --------------GIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPL 382
G+ GLSNLGNTC+MNSALQCL H P + EYFL + Y +IN +NPL
Sbjct: 314 GSNSLSILGKGEKGGLAGLSNLGNTCFMNSALQCLAHTPPIVEYFL-QDYSDDINRDNPL 372
Query: 383 GHKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLL 442
G G++A AFG LL L+ S G+++ APR FK + + F+GY Q DSQE LAFLL
Sbjct: 373 GMCGELAIAFGDLLKKLW--SSGRNSV-APRAFKTKLARFAPQFSGYNQHDSQELLAFLL 429
Query: 443 DGLHEDLNRVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLY 502
DGLHEDLN+V KPY+ + +D + DD +A +W+Y K RNDSVI+D+ G Y
Sbjct: 430 DGLHEDLNKVKRKPYIELKD--SDSRPDDE-----VAEELWNYHKARNDSVIVDVCQGQY 482
Query: 503 KSTLVCPNCNHVSITFDPYNDLTLPLPIENYWSTKVTIF--PQNSPPCTLEVELSKTSSY 560
KSTLVCP C +SITFDP+ L++PLP S VT+F + P V + K S
Sbjct: 483 KSTLVCPACGKISITFDPFMYLSVPLPSTLTRSMTVTVFYCDGSHLPMPYTVIVPKNGSI 542
Query: 561 NDLKAYVAQHANMHAND--LIGAEIFNHQFYNNYESNVEADYLPISELISESDTVIFYEV 618
DL + A + A D L+ AE+++H+ + +E+ +++ I + + ++ Y +
Sbjct: 543 RDLITALGT-ACLLAEDESLLLAEVYDHKIFKYFENPLDS-----LSSIKDDEHIVAYRL 596
Query: 619 H---RGQDDLVVPILNTRFEEGFKTP----------RLFGYPF 648
+ +G + IL+ G K P +LFG PF
Sbjct: 597 NQMPKGSGKAKLEILH----GGQKRPILESVRGRDVKLFGTPF 635
Score = 175 bits (444), Expect = 4e-43
Identities = 102/254 (40%), Positives = 143/254 (56%), Gaps = 14/254 (5%)
Query: 811 DTANDLATKSYTSPNPEENVTSSAEA-----LDGTLHLKVSPLLDVHNAIICEWEAVKVI 865
D D A++ +SP+ E + S E L L PL + I A +V+
Sbjct: 680 DATVDEASEILSSPDTEIDDASDRELSFRIFLTDERGLNFKPLQS--ESSISLGIATRVL 737
Query: 866 NVFDEDNGVNWDHPAILENLSLSEVRKTR---AQTEKSSITLDSCLRLFSQPEILGSADS 922
++E +D + + L EV KT +T + SI+L SCL F E LG D
Sbjct: 738 VEWNEGEHERYDSSYLSD---LPEVHKTSFSAKKTRQESISLFSCLEAFLAEEPLGPDDM 794
Query: 923 WYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSDKIDATVKFPIEGLDMSPYLS 982
W+CP+CK+H QA+K+++LW PDIL+ HLKRF R +KID V FP+ LD+S Y+
Sbjct: 795 WFCPSCKEHRQANKKLDLWKLPDILVFHLKRFTYSRYLKNKIDTFVNFPVHDLDLSKYVK 854
Query: 983 YKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSA 1042
K + ++ +Y+L AV NHYGGLGGGHYTAY + D +WY+FDDS V+ V+ +A
Sbjct: 855 NKND-QSYLYELYAVSNHYGGLGGGHYTAYAKLIDDNEWYHFDDSHVSSVNESEIKNSAA 913
Query: 1043 YLLFYRRRTSGNQT 1056
Y+LFYRR S +T
Sbjct: 914 YVLFYRRVRSETET 927
>At2g40930 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 914
Score = 204 bits (520), Expect = 5e-52
Identities = 165/501 (32%), Positives = 240/501 (46%), Gaps = 50/501 (9%)
Query: 311 VEVKQKSSNQHWPSNFFHYNKLNAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYK 370
VEV Q N + + + +G+ GL NLGNTC+MNSA+QCL+H PE YF +
Sbjct: 272 VEVSQSFDNTYSSTGV---TTRGSTAGLTGLLNLGNTCFMNSAIQCLVHTPEFASYF-QE 327
Query: 371 GYEREININNPLGHKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYG 430
Y +EIN NPLG G++A AFG LL L+AP T APR FK + + F+GY
Sbjct: 328 DYHQEINWQNPLGMVGELALAFGDLLRKLWAPG---RTPIAPRPFKAKLARFAPQFSGYN 384
Query: 431 QQDSQ----------EFLAFLLDGLHEDLNRVIEKPYVNKPEFPNDGQIDDTDQIVLLAA 480
Q DSQ E LAFLLDGLHEDLNRV KPY+N + DG+ D+ +A
Sbjct: 385 QHDSQLKEFEFFILQELLAFLLDGLHEDLNRVKHKPYINSRDA--DGRPDEE-----VAD 437
Query: 481 NMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLPIENYWSTKVTI 540
W RNDS+I+D+ G YKSTLVCP CN VS+TFDP+ L+LPL + VT+
Sbjct: 438 EFWKNHIARNDSIIVDVCQGQYKSTLVCPICNKVSVTFDPFMYLSLPLQFNTTRAITVTV 497
Query: 541 F--PQNSPPCTLEVELSKTSSYNDLKAYVAQHANM-HANDLIGAEIFNHQFYNNYESNVE 597
F + + P T+ V +SK DL + ++ + +L AEI N+ + +E +
Sbjct: 498 FSCDKTALPSTITVNVSKQGRCRDLIQALTNACSLKQSEELKLAEIRNNFIHRLFEDPL- 556
Query: 598 ADYLPISELISESDTVIFYEVHRGQDD-----LVVPILNTRFEEGFKTPRL--FGYPFFI 650
+P+S I + D + Y++ + ++ LV+ + + E T +L G P
Sbjct: 557 ---IPLSS-IKDDDHLAAYKLSKSSENTTLLRLVLRRRDQKAGERESTVQLKPCGTPLLS 612
Query: 651 ALSQAEQFSYGAIRKKIEKCYQNFSGGFSEFPIVGKTKMPDLSSMPLLEKRYSQCEIESI 710
+ S + + G KI QN F VGK D S R++ E E
Sbjct: 613 SASCGDALTKG----KIHCLVQNMLSPFRREESVGKKGNSDSSIPERRSARFNNTEEEDK 668
Query: 711 MPELEYINPEMSVD---EFFQLKILKVDSVSSNRRVTSFSGVSLGQTSDEPNSQIWIPPT 767
+ L+ S D L+++ D+ + N + L ++ W P
Sbjct: 669 VGGLKKAKKSNSSDLGASKLSLQLIDEDNKTINLPDNEAEAMKLPSSATVTIYLDWTPEL 728
Query: 768 ASLITYNHSELIRKALPEAIE 788
+ + E +LPE ++
Sbjct: 729 SGMYDITCLE----SLPEVLK 745
Score = 157 bits (398), Expect = 8e-38
Identities = 71/169 (42%), Positives = 111/169 (65%), Gaps = 3/169 (1%)
Query: 886 SLSEVRKTRAQTEKSS---ITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWN 942
SL EV K T+K+ ++L +CL F + E L + W+CP C + QASK+++LW
Sbjct: 739 SLPEVLKYGPTTKKARSEPLSLYACLEAFLREEPLVPDEMWFCPQCNERRQASKKLDLWR 798
Query: 943 TPDILLIHLKRFENQRSFSDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG 1002
P++L+IHLKRF RS K++ V FPI LD++ Y++ K + +Y+L A+ NHYG
Sbjct: 799 LPEVLVIHLKRFSYSRSMKHKLETFVNFPIHDLDLTKYVANKNLSQPQLYELYALTNHYG 858
Query: 1003 GLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
G+G GHYTA+ + D +WY FDDS ++ ++ ++ +G+AY+LFYRR++
Sbjct: 859 GMGSGHYTAHIKLLDDSRWYNFDDSHISHINEDDVKSGAAYVLFYRRKS 907
>Hs14211903 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1274
Score = 195 bits (495), Expect = 4e-49
Identities = 115/306 (37%), Positives = 170/306 (54%), Gaps = 23/306 (7%)
Query: 299 LKDYDSQIISLVVEVKQKSSNQHWP--------SNFFHYNKLNAPSGIMGLSNLGNTCYM 350
LK D Q LV+EV+ K + WP S+ +K+ G GLSNLGNTC+M
Sbjct: 360 LKIQDEQ--HLVIEVRNKDMS--WPEEMSFIANSSKIDRHKVPTEKGATGLSNLGNTCFM 415
Query: 351 NSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLLYSLFAPSYGQSTFY 410
NS++QC+ + L +YF+ + E+N NP+G KG +A +G L+ L++ G
Sbjct: 416 NSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWS---GTQKNV 472
Query: 411 APRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYVNKPEFPNDGQID 470
AP + TI Y F G+ QQDSQE LAFLLDGLHEDLNRV EKPYV + +DG+ D
Sbjct: 473 APLKLRWTIAKYAPRFNGFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKD--SDGRPD 530
Query: 471 DTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLPI 530
+AA WD +RN S+++DLF G +S + C C H+S+ FDP+N L+LPLP+
Sbjct: 531 WE-----VAAEAWDNHLRRNRSIVVDLFRGQLRSQVKCKTCGHISVRFDPFNFLSLPLPM 585
Query: 531 ENYWSTKVTIFP-QNSPPCTLEVELSKTSSYNDLKAYVAQHANMHANDLIGAEIFNHQFY 589
++Y ++T+ + P + L+ Y LK ++ +++ ++ AE+
Sbjct: 586 DSYMHLEITVIKLDGTTPVRYGLRLNMDEKYTGLKKQLSDLCGLNSEQILLAEVHGSNIK 645
Query: 590 NNYESN 595
N + N
Sbjct: 646 NFPQDN 651
Score = 81.6 bits (200), Expect = 7e-15
Identities = 48/118 (40%), Positives = 61/118 (51%), Gaps = 12/118 (10%)
Query: 874 VNWDHPAILENLSLSEVR----------KTRAQTEKSSITLDSCLRLFSQPEILGSADSW 923
V+WD A+ S+ R RAQ E I LDSCLR F+ E LG + +
Sbjct: 867 VDWDPTALHLRYQTSQERVVDEHESVEQSRRAQAEP--INLDSCLRAFTSEEELGENEMY 924
Query: 924 YCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSDKIDATVKFPIEGLDMSPYL 981
YC CK H A+K+++LW P IL+IHLKRF+ K VKFP E D S +L
Sbjct: 925 YCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNGRWIKSQKIVKFPRESFDPSAFL 982
Score = 57.8 bits (138), Expect = 1e-07
Identities = 26/60 (43%), Positives = 38/60 (63%), Gaps = 1/60 (1%)
Query: 991 VYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRR 1050
+Y+L A+ H G LGGGHY Y +N + KWY ++DS E+ P+ SAY+LFY ++
Sbjct: 1179 IYNLYAISCHSGILGGGHYVTYAKN-PNCKWYCYNDSSCKELHPDEIDTDSAYILFYEQQ 1237
>Hs22065611 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1089
Score = 191 bits (486), Expect = 5e-48
Identities = 104/266 (39%), Positives = 153/266 (57%), Gaps = 11/266 (4%)
Query: 331 KLNAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAH 390
K+ G GLSNLGNTC+MNS++QC+ + L +YF+ + E+N NP+G KG +A
Sbjct: 207 KVPTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAK 266
Query: 391 AFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLN 450
+G L+ L++ G AP + TI Y F G+ QQDSQE LAFLLDGLHEDLN
Sbjct: 267 CYGDLVQELWS---GTQKSVAPLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHEDLN 323
Query: 451 RVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPN 510
RV EKPYV + +DG+ D +AA WD +RN S+I+DLF G +S + C
Sbjct: 324 RVHEKPYVELKD--SDGRPDWE-----VAAEAWDNHLRRNRSIIVDLFHGQLRSQVKCKT 376
Query: 511 CNHVSITFDPYNDLTLPLPIENYWSTKVTIFP-QNSPPCTLEVELSKTSSYNDLKAYVAQ 569
C H+S+ FDP+N L+LPLP+++Y ++T+ + P + L+ Y LK +
Sbjct: 377 CGHISVRFDPFNFLSLPLPMDSYMDLEITVIKLDGTTPVRYGLRLNMDEKYTGLKKQLRD 436
Query: 570 HANMHANDLIGAEIFNHQFYNNYESN 595
+++ ++ AE+ + N + N
Sbjct: 437 LCGLNSEQILLAEVHDSNIKNFPQDN 462
Score = 74.7 bits (182), Expect = 8e-13
Identities = 39/88 (44%), Positives = 51/88 (57%), Gaps = 2/88 (2%)
Query: 894 RAQTEKSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKR 953
RAQ E I LDSCLR F+ E LG ++ +YC CK H A+K+++LW P L+IHLKR
Sbjct: 708 RAQAEP--INLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKR 765
Query: 954 FENQRSFSDKIDATVKFPIEGLDMSPYL 981
F+ K V+F E D S +L
Sbjct: 766 FQFVNDQWIKSQKIVRFLRESFDPSAFL 793
Score = 55.1 bits (131), Expect = 7e-07
Identities = 25/60 (41%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 991 VYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRR 1050
+Y+L A+ H G L GGHY Y +N + KWY ++DS E+ P+ SAY+LFY ++
Sbjct: 994 IYNLYAISCHSGILSGGHYITYAKN-PNCKWYCYNDSSCEELHPDEIDTDSAYILFYEQQ 1052
>At4g10570 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 928
Score = 189 bits (481), Expect = 2e-47
Identities = 129/340 (37%), Positives = 185/340 (53%), Gaps = 46/340 (13%)
Query: 337 GIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYERE--------------ININNPL 382
G+ GLSNLGNTC+MNSALQCL H P + EYFL + Y + +NI L
Sbjct: 293 GLAGLSNLGNTCFMNSALQCLAHTPPIVEYFL-QDYMLDTYMFYFLVMVLTCILNIILTL 351
Query: 383 GHKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLL 442
+G++A AFG LL L+ S G++ APR FK + + F+GY Q DSQE LAFLL
Sbjct: 352 NFQGELAIAFGDLLKKLW--SSGRNAV-APRAFKTKLARFAPQFSGYNQHDSQELLAFLL 408
Query: 443 DGLHEDLNRVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLY 502
DGLHEDLN+V KPY+ + +D + DD +A +W+Y K RNDSVI+D+ G Y
Sbjct: 409 DGLHEDLNKVKRKPYIELKD--SDSRPDDE-----VAEELWNYHKARNDSVIVDVCQGQY 461
Query: 503 KSTLVCPNCNHVSITFDPYNDLTLPLPIENYWSTKVTIF--PQNSPPCTLEVELSKTSSY 560
KSTLVCP C +SITFDP+ L++PLP S +T+F + P V + K S
Sbjct: 462 KSTLVCPVCGKISITFDPFMYLSVPLPSTLTRSMTITVFYCDGSRLPMPYTVIVPKQGSI 521
Query: 561 NDLKAYVAQHANMHAND-LIGAEIFNHQFYNNYESNVEADYLPISEL--ISESDTVIFY- 616
DL + + ++ L+ AE+++H+ + +E +P+ L I + + ++ Y
Sbjct: 522 RDLITALGTACCLAEDESLLLAEVYDHKIFRYFE-------IPLDSLSAIKDDEHIVAYR 574
Query: 617 --EVHRGQDDLVVPILNTRFEEGF------KTPRLFGYPF 648
++ +G + IL+ E +LFG PF
Sbjct: 575 LNQIPKGSRKAKLEILHGGQERAVLDSVRGSDVKLFGTPF 614
Score = 181 bits (458), Expect = 8e-45
Identities = 103/256 (40%), Positives = 144/256 (56%), Gaps = 14/256 (5%)
Query: 809 VSDTANDLATKSYTSPNPEENVTSSAEA-----LDGTLHLKVSPLLDVHNAIICEWEAVK 863
++D D A+ +SP+ E + S E L L + PL + I +
Sbjct: 657 LADATVDQASGILSSPDTEIDNASDRELSFRIFLTDERGLNIKPLQS--ESSISPGTVTR 714
Query: 864 VINVFDEDNGVNWDHPAILENLSLSEVRKTR---AQTEKSSITLDSCLRLFSQPEILGSA 920
V+ ++E +D + + L EV KT +T + SI+L SCL F E LG
Sbjct: 715 VLVEWNEGEHERYDSSYLSD---LPEVHKTSFSAKKTRQESISLFSCLEAFLAEEPLGPD 771
Query: 921 DSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSDKIDATVKFPIEGLDMSPY 980
D W+CP+CK+H QA+K+++LW PDIL+ HLKRF R +KID V FP+ LD+S Y
Sbjct: 772 DMWFCPSCKEHRQANKKLDLWKLPDILVFHLKRFTYSRYLKNKIDTFVNFPVHDLDLSKY 831
Query: 981 LSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAG 1040
+ K G++ +Y+L AV NHYGGLGGGHYTAY + D KWY+FDDS V+ V+
Sbjct: 832 VK-NKNGQSYLYELYAVSNHYGGLGGGHYTAYAKLIDDNKWYHFDDSHVSSVNESEIRNS 890
Query: 1041 SAYLLFYRRRTSGNQT 1056
+AY+LFYRR S +T
Sbjct: 891 AAYVLFYRRVRSETET 906
>Hs4758564_2 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 288
Score = 189 bits (481), Expect = 2e-47
Identities = 102/254 (40%), Positives = 149/254 (58%), Gaps = 11/254 (4%)
Query: 331 KLNAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAH 390
K+ G GLSNLGNTC+MNS++QC+ + L +YF+ + E+N NP+G KG +A
Sbjct: 26 KVPTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAK 85
Query: 391 AFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLN 450
+G L+ L++ G AP + TI Y F G+ QQDSQE LAFLLDGLHEDLN
Sbjct: 86 CYGDLVQELWS---GTQKSVAPLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHEDLN 142
Query: 451 RVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPN 510
RV EKPYV + +DG+ D +AA WD +RN S+I+DLF G +S + C
Sbjct: 143 RVHEKPYVELKD--SDGRPDWE-----VAAEAWDNHLRRNRSIIVDLFHGQLRSQVKCKT 195
Query: 511 CNHVSITFDPYNDLTLPLPIENYWSTKVTIFP-QNSPPCTLEVELSKTSSYNDLKAYVAQ 569
C H+S+ FDP+N L+LPLP+++Y ++T+ + P + L+ Y LK +
Sbjct: 196 CGHISVRFDPFNFLSLPLPMDSYMDLEITVIKLDGTTPVRYGLRLNMDEKYTGLKKQLRD 255
Query: 570 HANMHANDLIGAEI 583
+++ ++ AE+
Sbjct: 256 LCGLNSEQILLAEV 269
>CE19500 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 900
Score = 182 bits (462), Expect = 3e-45
Identities = 95/211 (45%), Positives = 128/211 (60%), Gaps = 20/211 (9%)
Query: 330 NKLNAPS-----------GIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREINI 378
N N+PS G GLSNLGNTC+M SA QCL ++P L EYFL Y+ +IN
Sbjct: 255 NSYNSPSPSTGVVTRTTPGACGLSNLGNTCFMASAFQCLSNMPPLREYFLANTYQNDINE 314
Query: 379 NNPLGHKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFL 438
+NPLG G +A A G L+ +++ Y PR FK+ IG + F GY QQD+ E +
Sbjct: 315 DNPLGTHGHLAMAVGELMKGMWSGDYASIN---PRKFKSIIGQFAPRFNGYSQQDAHELM 371
Query: 439 AFLLDGLHEDLNRVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLF 498
A++LDGLHEDLNR+ +KPY+ + D ++ + + AA W+ K RNDS+I+D
Sbjct: 372 AYVLDGLHEDLNRIKKKPYIEDSD--EDAKLPEAE----YAAKSWEVYKMRNDSIIVDTL 425
Query: 499 VGLYKSTLVCPNCNHVSITFDPYNDLTLPLP 529
G KSTL+CP C +SI FDP+ L+LPLP
Sbjct: 426 HGQLKSTLICPVCEKISIKFDPFGYLSLPLP 456
Score = 138 bits (348), Expect = 5e-32
Identities = 86/262 (32%), Positives = 132/262 (49%), Gaps = 32/262 (12%)
Query: 855 IICEWEAVKVINVFDEDNGVNWDHPAILENLSLSEVRKTRAQTEKSSITLDSCLRLFSQP 914
I+ +W+ +K+ N + + I +++S RK + L L F+
Sbjct: 667 IVFQWKDLKIFNQYKGNE-------LIEREMTVSTRRK---------VLLQETLDWFTTK 710
Query: 915 EILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSDKIDATVKFPIEG 974
E LG DSWYCP CK+H +A+KQ+ LW P+IL++HLKRF+ + +K+ V P+ G
Sbjct: 711 EQLGEQDSWYCPQCKKHERATKQLALWKLPEILILHLKRFQYTKWSREKLTWEVVIPVRG 770
Query: 975 LDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSP 1034
LD++ ++ E +YDLIAV HYG L GGHYTA N + KW+ F+DS N P
Sbjct: 771 LDLTDKVA-NPNHEKAIYDLIAVSRHYGSLSGGHYTAIGYNDREQKWFDFNDSSANPTYP 829
Query: 1035 --ENSIAGSAYLLFYRRRTSGNQTLGNGKLRDIIDISRKEYEQKQDEFMTNVETLYAATH 1092
E + Y+L YRRR + NGK + +S + + + AA
Sbjct: 830 PAEPYESSDPYILVYRRRKLDS----NGKPIEPSAVSESLHSRPKRG---------AAPT 876
Query: 1093 TDTESEASDSDRSSVDEEMDSD 1114
+ + ++ S R VDE M+ +
Sbjct: 877 ISSATSSASSSRHQVDENMEME 898
>Hs20472401 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1320
Score = 179 bits (453), Expect = 3e-44
Identities = 113/285 (39%), Positives = 161/285 (55%), Gaps = 20/285 (7%)
Query: 337 GIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLL 396
G GL NLGNTC+MNS +Q L + EL ++F + +E EIN NNPLG G +A F LL
Sbjct: 497 GFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNPLGTGGRLAIGFAVLL 556
Query: 397 YSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKP 456
+L+ G + P K + S F GY Q D+QEF+AFLLDGLHEDLNR+ KP
Sbjct: 557 RALWK---GTHHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKP 613
Query: 457 YVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSI 516
Y + +DG+ D+ ++A W K RNDS I+DLF G YKS LVCP C VSI
Sbjct: 614 YTETVD--SDGRPDE-----VVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSI 666
Query: 517 TFDPYNDLTLPLPIENYWSTKVTIFPQ--NSPPCTLEVELSK-TSSYNDLKAYVAQHANM 573
TFDP+ L +PLP + V F + +S P V +SK S+ +++ ++Q ++
Sbjct: 667 TFDPFLYLPVPLP-QKQKVLPVFYFAREPHSKPIKFLVSVSKENSTASEVLDSLSQSVHV 725
Query: 574 HANDLIGAEIFNHQFYNNYESNVEADYLPISELISESDTVIFYEV 618
+L AE+ ++F+ + + D +S SDT++ +E+
Sbjct: 726 KPENLRLAEVIKNRFHRVFLPSHSLD------TVSPSDTLLCFEL 764
Score = 150 bits (380), Expect = 9e-36
Identities = 78/159 (49%), Positives = 100/159 (62%), Gaps = 10/159 (6%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSF-- 960
TLD CL LF++PE+L ++WYCP CKQH +ASKQ+ LW P++L++ LKRF + RSF
Sbjct: 1061 TLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVLIVQLKRF-SFRSFIW 1119
Query: 961 SDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCR------ 1014
DKI+ V+FP+ LD+S + +KE + YDL AV NHYGG+ GGHYTA R
Sbjct: 1120 RDKINDLVEFPVRNLDLSKFCIGQKEEQLPSYDLYAVINHYGGMIGGHYTACARLPNDRS 1179
Query: 1015 -NFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRRTS 1052
D W FDDS V V + AY+LFYRRR S
Sbjct: 1180 SQRSDVGWRLFDDSTVTTVDESQVVTRYAYVLFYRRRNS 1218
>CE03146 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1095
Score = 172 bits (436), Expect = 3e-42
Identities = 103/285 (36%), Positives = 153/285 (53%), Gaps = 19/285 (6%)
Query: 337 GIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLL 396
G GL N+GNTC+MN+ LQ L++ EL EYFL Y+ EIN NPLG +G +A AF +
Sbjct: 421 GYTGLRNIGNTCFMNAVLQMLVNNIELREYFLRNHYQPEINETNPLGSEGRLAKAFADFM 480
Query: 397 YSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKP 456
+ +++ G P KN + S FA + Q D+ EFL+FLLDGLHED+NRV +KP
Sbjct: 481 HQMWS---GHQKAIEPTQIKNIVAEKASQFANFAQHDAHEFLSFLLDGLHEDVNRVKKKP 537
Query: 457 YVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSI 516
E +D +++ W RNDS+ +DLF G KS + CPNC+ VSI
Sbjct: 538 LTGTVESHGRHDLDVSNE-------AWKNHILRNDSIFVDLFHGQLKSHVQCPNCDRVSI 590
Query: 517 TFDPYNDLTLPLPIENYWSTKVTIFP--QNSPPCTLEVELSKTSSYNDLKAYVAQHANMH 574
TFDP+ L +P P +N ST + +P + P L V S + D + V++ +
Sbjct: 591 TFDPFVYLPVPFP-KNKQSTDLIFWPLENQTKPYKLTVSYSTEGTVADFLSVVSETVRVP 649
Query: 575 ANDLIGAEIFNHQFYNNYESNVEADYLPISELISESDTVIFYEVH 619
+L E H+F Y +++ +S+++S D + ++ H
Sbjct: 650 TRNLRACEAICHKFDKIYSLDMK-----VSDIVS-PDRLFVFQTH 688
Score = 97.4 bits (241), Expect = 1e-19
Identities = 60/171 (35%), Positives = 90/171 (52%), Gaps = 14/171 (8%)
Query: 894 RAQTEKSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKR 953
++ +++ L L LFS+ E L +SWYC CK++ +A+K+++L+ P +L+I LKR
Sbjct: 900 KSNNSETNPHLTQMLDLFSETERLKPEESWYCSTCKENVEATKKLQLYRLPPVLIIQLKR 959
Query: 954 F-------ENQRSFSDKIDATVKFPIEGLDMSPYLSYKKEGEND-VYDLIAVDNHYGGLG 1005
F ++ + K +V++P+E LDMSP+L+ N +YDL V H G
Sbjct: 960 FVYTAFTYQSSMARRSKDTRSVEYPLESLDMSPFLAETSPHPNSTMYDLTGVVCHSGNSY 1019
Query: 1006 GGHYTAYCR--NFIDGK----WYYFDDSRVNEVSPENSIAGSAYLLFYRRR 1050
GHY + R +F K W FDDS V S AYLLFY+ R
Sbjct: 1020 FGHYISMGRLADFDSSKTKIEWRNFDDSTVARQSTSTLQTEDAYLLFYKMR 1070
>7293731 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1351
Score = 166 bits (421), Expect = 2e-40
Identities = 99/257 (38%), Positives = 144/257 (55%), Gaps = 12/257 (4%)
Query: 332 LNAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHA 391
++AP G GL NLGNTC+MN+ALQ L + L +YF + + E+N N LG KG +A
Sbjct: 714 VHAP-GATGLHNLGNTCFMNAALQVLFNTQPLAQYFQREMHRFEVNAANKLGTKGQLAMR 772
Query: 392 FGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNR 451
+ LL ++ + + AP + + Y FAG GQ DSQE L +LLD LHEDLNR
Sbjct: 773 YAELLKEVWTAT---TRSVAPLKLRFCVNKYAPQFAGGGQHDSQELLEWLLDALHEDLNR 829
Query: 452 VIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNC 511
V+EKPY + ++G+ D ++AA W RN S+I+DLF G KS + C C
Sbjct: 830 VMEKPYSELKD--SNGRPDK-----IVAAEAWSQHHARNQSIIIDLFYGQLKSKVSCLGC 882
Query: 512 NHVSITFDPYNDLTLPLPIENY-WSTKVTIFPQNSPPCTLEVELSKTSSYNDLKAYVAQH 570
H S+ FDP++ L+LPLP+ENY + + I S P L+ Y+ LK ++
Sbjct: 883 GHESVRFDPFSLLSLPLPVENYIYFEVLVILLDGSVPIKYGFRLNSDCKYSHLKHKLSTM 942
Query: 571 ANMHANDLIGAEIFNHQ 587
++ N ++ E++N Q
Sbjct: 943 CSLPPNLMLVCELWNSQ 959
>Hs4827054 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 1118
Score = 164 bits (414), Expect = 1e-39
Identities = 99/250 (39%), Positives = 138/250 (54%), Gaps = 27/250 (10%)
Query: 338 IMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLLY 397
+ GL NLGNTCYMNS LQCL + P L +YF Y+ +IN +N LGHKG+VA FG ++
Sbjct: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
Query: 398 SLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPY 457
+L+ GQ + +P++FK TIG N FAGY QQDSQE L FL+DGLHEDLN+ +
Sbjct: 836 ALWT---GQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNR-- 890
Query: 458 VNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSIT 517
+ + N+ +DD A + W K+ N+S+I+ LF G +KST+ C C+ S T
Sbjct: 891 -KRYKEENNDHLDD----FKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRT 945
Query: 518 FDPYNDLTLPLPIENYWSTKVTIFPQNSPPCTLEVEL---SKTSSYNDLKAYVAQHANMH 574
F+ + L+LPL ++ CTL+ L SK D + H
Sbjct: 946 FEAFMYLSLPL--------------ASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRAR 991
Query: 575 ANDLIGAEIF 584
+ L EI+
Sbjct: 992 RDSLKKIEIW 1001
Score = 141 bits (356), Expect = 6e-33
Identities = 65/148 (43%), Positives = 93/148 (61%), Gaps = 1/148 (0%)
Query: 900 SSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRS 959
S TL CLRLFS+ E L + +YC +C+ + K+IE+W P +LL+HLKRF
Sbjct: 960 SKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGR 1019
Query: 960 FSDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDG 1019
+ K+ +V FP+E LD+S Y+ K Y+L +V NHYGGL GGHYTAYC+N
Sbjct: 1020 WKQKLQTSVDFPLENLDLSQYVIGPKNNLKK-YNLFSVSNHYGGLDGGHYTAYCKNAARQ 1078
Query: 1020 KWYYFDDSRVNEVSPENSIAGSAYLLFY 1047
+W+ FDD V+++S + + +AY+LFY
Sbjct: 1079 RWFKFDDHEVSDISVSSVKSSAAYILFY 1106
>Hs22068900 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 909
Score = 153 bits (387), Expect = 1e-36
Identities = 84/224 (37%), Positives = 122/224 (53%), Gaps = 32/224 (14%)
Query: 852 HNAIICEW--EAVKVINVFDEDNGVNWDHPAILENLSLSEVRKTRAQTEKSSITLDSCLR 909
H ++ EW E + V ED ++ E++ L R + QT TL C +
Sbjct: 110 HVKLVVEWDKETRDFLFVNTED-----EYIPDAESVRLQRERHHQPQT----CTLSQCFQ 160
Query: 910 LFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSDKIDATVK 969
L+++ E L D+W CP+CKQ Q S + LW PD+L+IHLKRF + K+ VK
Sbjct: 161 LYTKEERLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQEGDRRMKLQNMVK 220
Query: 970 FPIEGLDMSPYLSYKKEG---------------------ENDVYDLIAVDNHYGGLGGGH 1008
FP+ GLDM+P++ + + E+ +YDL AV NH+G + GGH
Sbjct: 221 FPLTGLDMTPHVVKRSQSSWSLPSHWSPWRRPYGLGRDPEDYIYDLYAVCNHHGTMQGGH 280
Query: 1009 YTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRRTS 1052
YTAYC+N +DG WY FDDS V ++S + +AY+LFY+RRT+
Sbjct: 281 YTAYCKNSVDGLWYCFDDSDVQQLSEDEVCTQTAYILFYQRRTA 324
>Hs22063256 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 675
Score = 144 bits (363), Expect = 9e-34
Identities = 81/235 (34%), Positives = 121/235 (51%), Gaps = 39/235 (16%)
Query: 856 ICEWEAVKVINVFDEDN------GVNWDHPAILENL--SLSEVRKTRAQT--------EK 899
+C W +V+++ V WD ++ E L SL E R A + ++
Sbjct: 168 LCHWAVDRVLHLRRPGGPPHVKLAVEWDS-SVKERLFGSLQEERAQDADSVWQQQQAHQQ 226
Query: 900 SSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRS 959
S TLD C + +++ E L D+W CP+C+ Q ++ LW PDIL+IHLKRF
Sbjct: 227 HSCTLDECFQFYTKEEQLAQDDAWKCPHCQVLQQGMVKLSLWTLPDILIIHLKRFCQVGE 286
Query: 960 FSDKIDATVKFPIEGLDMSPYLSYKKEGE----------------------NDVYDLIAV 997
+K+ VKFP+ GL+M+P+++ + + +YDL AV
Sbjct: 287 RRNKLSTLVKFPLSGLNMAPHVAQRSTSPEAGLGPWPSWKQPDCLPTSYPLDFLYDLYAV 346
Query: 998 DNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRRTS 1052
NH+G L GGHYTAYCRN +DG+WY +DDS V + + AY+LFY++R S
Sbjct: 347 CNHHGNLQGGHYTAYCRNSLDGQWYSYDDSTVEPLREDEVNTRGAYILFYQKRNS 401
>YDR069c [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 926
Score = 143 bits (361), Expect = 1e-33
Identities = 109/349 (31%), Positives = 163/349 (46%), Gaps = 24/349 (6%)
Query: 197 NGNANIYPGSSRHSIDHKIPLMFTMSRLATMKDVIQRCLEVFYAKEPHLDKSSLTHRIWY 256
N N+N+Y SS PL L + V L + Y + PHL K+S T +
Sbjct: 419 NSNSNLYSISSLSISSSPSPLP-----LHSPDPVKGNSLPINYPETPHLWKNSETDFMTN 473
Query: 257 INERVAD-------PKSTQTLLSNYVLSPSAFLELQTKHEITKSMYSRQLKDYDSQIISL 309
E++ P +T+ + S + + +M S S I
Sbjct: 474 QREQLNHNSFAHIAPINTKAITSPSRTATPKLQRFPQTISMNLNMNSNGHSSATSTIQPS 533
Query: 310 VVEVKQKSSNQHW---PSNFFHYNKLNAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEY 366
+ + S H P++ +Y+ A +GL NLGN+CYMN +QC+L EL +
Sbjct: 534 CLSLSNNDSLDHTDVTPTSSHNYDLDFA----VGLENLGNSCYMNCIIQCILGTHELTQI 589
Query: 367 FLYKGYEREININNPLGHKGDVAHAFGHLLYSLFAPSY--GQSTFYAPRNFKNTIGHYNS 424
FL Y + ININ+ LG KG +A F L++ ++ + +P FK G NS
Sbjct: 590 FLDDSYAKHININSKLGSKGILAKYFARLVHMMYKEQVDGSKKISISPIKFKLACGSVNS 649
Query: 425 LFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYVNKPEFPNDGQIDDTDQIVLLAANM-W 483
LF QQD QEF FLLDGLHEDLN+ P + E + + + +A+++ W
Sbjct: 650 LFKTASQQDCQEFCQFLLDGLHEDLNQCGSNPPLK--ELSQEAEARREKLSLRIASSIEW 707
Query: 484 DYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLPIEN 532
+ + SVI+DLF G Y S L C C+H S T+ P+ L++P+P +N
Sbjct: 708 ERFLTTDFSVIVDLFQGQYASRLKCKVCSHTSTTYQPFTVLSIPIPKKN 756
Score = 95.1 bits (235), Expect = 6e-19
Identities = 56/172 (32%), Positives = 94/172 (54%), Gaps = 22/172 (12%)
Query: 896 QTEKSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFE 955
+ +++IT++ C R F++ E L + W CP+C++ ++KQ+ + P L++HLKRF+
Sbjct: 755 KNSRNNITIEDCFREFTKCENLEVDEQWLCPHCEKRQPSTKQLTITRLPRNLIVHLKRFD 814
Query: 956 NQRSFSDKIDATVKFPIEGLDMSPYLSYKKEGE-----ND------------VYDLIAVD 998
N +K + V +P LD++P+ + +G ND Y+L V
Sbjct: 815 N---LLNKNNDFVIYPFL-LDLTPFWANDFDGVFPPGVNDDELPIRGQIPPFKYELYGVA 870
Query: 999 NHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEV-SPENSIAGSAYLLFYRR 1049
H+G L GGHYTAY + + W YFDD++ V + ++I +AY+LFY R
Sbjct: 871 CHFGTLYGGHYTAYVKKGLKKGWLYFDDTKYKPVKNKADAINSNAYVLFYHR 922
>HsM19923759 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 605
Score = 140 bits (354), Expect = 1e-32
Identities = 85/202 (42%), Positives = 112/202 (55%), Gaps = 21/202 (10%)
Query: 337 GIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHA----- 391
G+ GL NLGNTC+MNS LQCL + EL +Y L + Y R++ H G AH
Sbjct: 265 GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDL-------HHGSNAHTALVEE 317
Query: 392 FGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNR 451
F L+ +++ S + +P FK I Y F GY QQD+QEFL FLLDGLH ++NR
Sbjct: 318 FAKLIQTIWTSS--PNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNR 375
Query: 452 VIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNC 511
V +P N PE N + D ++ MW +R DS I DLFVG KS+L C +C
Sbjct: 376 VTLRPKSN-PE--NLDHLPDDEK----GRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDC 428
Query: 512 NHVSITFDPYNDLTLPLPIENY 533
+ S FDP+ DL+LP+ Y
Sbjct: 429 GYCSTVFDPFWDLSLPIAKRGY 450
Score = 110 bits (276), Expect = 1e-23
Identities = 56/146 (38%), Positives = 82/146 (55%), Gaps = 2/146 (1%)
Query: 902 ITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFS 961
+TL C+RLF++ ++L + C C+ + K+ + P IL++HLKRF R +
Sbjct: 453 VTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRT 512
Query: 962 DKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKW 1021
K+ V FP+ LD+ + S + + VY+L AV NH G GGHYTAYCR+ G+W
Sbjct: 513 SKLTTFVNFPLRDLDLREFAS--ENTNHAVYNLYAVSNHSGTTMGGHYTAYCRSPGTGEW 570
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFY 1047
+ F+DS V +S AYLLFY
Sbjct: 571 HTFNDSSVTPMSSSQVRTSDAYLLFY 596
>Hs21361712 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 605
Score = 139 bits (350), Expect = 3e-32
Identities = 84/202 (41%), Positives = 111/202 (54%), Gaps = 21/202 (10%)
Query: 337 GIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHA----- 391
G+ GL NLGNTC+MNS LQCL + EL +Y L + Y R++ H G AH
Sbjct: 265 GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDL-------HHGSNAHTALVEE 317
Query: 392 FGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNR 451
F L+ +++ S + +P FK I Y F GY QQD+QEFL FLLDGLH ++NR
Sbjct: 318 FAKLIQTIWTSS--PNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNR 375
Query: 452 VIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNC 511
V +P N PE N + D ++ MW +R DS I DLFVG K +L C +C
Sbjct: 376 VTLRPKSN-PE--NLDHLPDDEK----GRQMWRKYLEREDSRIGDLFVGQLKGSLTCTDC 428
Query: 512 NHVSITFDPYNDLTLPLPIENY 533
+ S FDP+ DL+LP+ Y
Sbjct: 429 GYCSTVFDPFWDLSLPIAKRGY 450
Score = 107 bits (268), Expect = 9e-23
Identities = 55/146 (37%), Positives = 81/146 (54%), Gaps = 2/146 (1%)
Query: 902 ITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFS 961
+TL C+RLF++ ++L + C C+ + K+ + P IL++ LKRF R +
Sbjct: 453 VTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLRLKRFSESRIRT 512
Query: 962 DKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKW 1021
K+ V FP+ LD+ + S + + VY+L AV NH G GGHYTAYCR+ G+W
Sbjct: 513 SKLTTFVNFPLRDLDLREFAS--ENTNHAVYNLYAVSNHSGTTMGGHYTAYCRSPGTGEW 570
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFY 1047
+ F+DS V +S AYLLFY
Sbjct: 571 HTFNDSSVTPMSSSQVRTSDAYLLFY 596
>Hs22066171 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 246
Score = 128 bits (321), Expect = 6e-29
Identities = 78/180 (43%), Positives = 105/180 (58%), Gaps = 17/180 (9%)
Query: 299 LKDYDSQIISLVVEVKQKSSNQHWP--------SNFFHYNKLNAPSGIMGLSNLGNTCYM 350
LK D Q LV+EV+ K + WP S+ +K+ G GLSNLGNTC+M
Sbjct: 69 LKIQDEQ--HLVIEVRNKDMS--WPEEMSFISNSSKIDRHKVLTEKGATGLSNLGNTCFM 124
Query: 351 NSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLLYSLFAPSYGQSTFY 410
NS++QC+ + L +YF+ + E+N NP+G KG +A +G L+ L++ G
Sbjct: 125 NSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWS---GTQKNV 181
Query: 411 APRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYVNKPEFPNDGQID 470
AP + TI Y F G+ QQD+QE LAFLLDGLHEDLNRV EKPYV + +DG+ D
Sbjct: 182 APLKLRWTIAKYAPRFNGFQQQDAQELLAFLLDGLHEDLNRVHEKPYVELKD--SDGRPD 239
>HsM18874088 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 942
Score = 126 bits (317), Expect = 2e-28
Identities = 63/154 (40%), Positives = 86/154 (54%)
Query: 902 ITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFS 961
+TL CL F + L + + C CK+ K ++ N P+IL IHLKRF ++ FS
Sbjct: 567 VTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFS 626
Query: 962 DKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKW 1021
KI V FP+EGLD+ P+L+ + YDL++V H+G GHY AYCRN ++ W
Sbjct: 627 TKISTHVSFPLEGLDLQPFLAKDSPAQIVTYDLLSVICHHGTASSGHYIAYCRNNLNNLW 686
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRRTSGNQ 1055
Y FDD V EVS AY+LFYR+ + Q
Sbjct: 687 YEFDDQSVTEVSESTVQNAEAYVLFYRKSSEEAQ 720
Score = 70.1 bits (170), Expect = 2e-11
Identities = 44/117 (37%), Positives = 60/117 (50%), Gaps = 8/117 (6%)
Query: 337 GIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLL 396
G+ GL N+GNTCYMN+ALQ L + P L ++FL G + K + ++ L+
Sbjct: 183 GLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTD------KKPAICKSYLKLM 236
Query: 397 YSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVI 453
L+ S S P I N F GY QQD+QEFL L+D LHE+L +
Sbjct: 237 TELWYKSRPGSV--VPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKEQV 291
>Hs21489975 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 911
Score = 126 bits (317), Expect = 2e-28
Identities = 63/154 (40%), Positives = 86/154 (54%)
Query: 902 ITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFS 961
+TL CL F + L + + C CK+ K ++ N P+IL IHLKRF ++ FS
Sbjct: 536 VTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFS 595
Query: 962 DKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKW 1021
KI V FP+EGLD+ P+L+ + YDL++V H+G GHY AYCRN ++ W
Sbjct: 596 TKISTHVSFPLEGLDLQPFLAKDSPAQIVTYDLLSVICHHGTASSGHYIAYCRNNLNNLW 655
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRRTSGNQ 1055
Y FDD V EVS AY+LFYR+ + Q
Sbjct: 656 YEFDDQSVTEVSESTVQNAEAYVLFYRKSSEEAQ 689
Score = 70.1 bits (170), Expect = 2e-11
Identities = 44/117 (37%), Positives = 60/117 (50%), Gaps = 8/117 (6%)
Query: 337 GIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLL 396
G+ GL N+GNTCYMN+ALQ L + P L ++FL G + K + ++ L+
Sbjct: 152 GLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTD------KKPAICKSYLKLM 205
Query: 397 YSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVI 453
L+ S S P I N F GY QQD+QEFL L+D LHE+L +
Sbjct: 206 TELWYKSRPGSV--VPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKEQV 260
>7303210 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 857
Score = 126 bits (317), Expect = 2e-28
Identities = 62/149 (41%), Positives = 87/149 (57%)
Query: 901 SITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSF 960
S+TL C+ F + L + + C C + K + P++L IHLKRF N S+
Sbjct: 274 SVTLYDCMASFFSADELKGDNMYSCERCNKLRTGIKYSRVLTLPEVLCIHLKRFRNDLSY 333
Query: 961 SDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGK 1020
S KI + V FP+EG DM PY+ + E +Y+L +V H+G +GGGHYT + RN ++GK
Sbjct: 334 SSKISSDVYFPLEGFDMRPYIHKDCKSEVAIYNLSSVICHHGTVGGGHYTCFARNTLNGK 393
Query: 1021 WYYFDDSRVNEVSPENSIAGSAYLLFYRR 1049
WY FDD V EVS E + AY+LFY +
Sbjct: 394 WYEFDDQFVTEVSSELVQSCQAYVLFYHK 422
Score = 52.4 bits (124), Expect = 5e-06
Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 2/106 (1%)
Query: 350 MNSALQCLLHIPELNEYFLYKGYEREININNPLGH--KGDVAHAFGHLLYSLFAPSYGQS 407
MNSALQ L ++P + YF+ E G +A ++ L+ ++
Sbjct: 1 MNSALQALSNLPPMTHYFINCSDLVEYIAEQSARRCKPGGLAKSYRRLMQEIWQDVDDPK 60
Query: 408 TFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVI 453
F APR I + +F GY Q D+QEFL +D LHE+L +
Sbjct: 61 EFIAPRGILYGIRTVHPMFRGYQQHDTQEFLRCFMDQLHEELTEQV 106
>Hs5730108 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 913
Score = 125 bits (313), Expect = 5e-28
Identities = 60/148 (40%), Positives = 88/148 (58%)
Query: 902 ITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFS 961
+TL+ CL F + L + + C CK+ K ++ P+IL IHLKRF ++ +S
Sbjct: 536 VTLEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVMYS 595
Query: 962 DKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKW 1021
KI++ V FP+EGLD+ P+L+ + + YDL++V H+G G GHY AYC+N I+G+W
Sbjct: 596 FKINSHVSFPLEGLDLRPFLAKECTSQITTYDLLSVICHHGTAGSGHYIAYCQNVINGQW 655
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRR 1049
Y FDD V EV Y+LFYR+
Sbjct: 656 YEFDDQYVTEVHETVVQNAEGYVLFYRK 683
Score = 72.8 bits (177), Expect = 3e-12
Identities = 41/119 (34%), Positives = 65/119 (54%), Gaps = 8/119 (6%)
Query: 335 PSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGH 394
P G+ G+ NLGN+CYMN+ALQ L + P L ++FL G + K + ++
Sbjct: 141 PRGLTGMKNLGNSCYMNAALQALSNCPPLTQFFLECGGLVRTD------KKPALCKSYQK 194
Query: 395 LLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVI 453
L+ ++ + ++ P + + I N +F GY QQD+QEFL L+D LHE+L +
Sbjct: 195 LVSEVWHKK--RPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELKEPV 251
>7295645 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 857
Score = 122 bits (305), Expect = 5e-27
Identities = 67/193 (34%), Positives = 99/193 (50%), Gaps = 17/193 (8%)
Query: 337 GIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLL 396
G+ GL N+GNTC+MNS +QCL H EL + R ++ + + H F L+
Sbjct: 530 GLCGLRNIGNTCFMNSVIQCLSHTQELTRFLRSHHGSRSLSTKDQ-----QILHEFAKLI 584
Query: 397 YSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKP 456
++ + T P K + +++ Y QQD+QEFL F LD LH LN ++
Sbjct: 585 QEMWTANVHTVT---PMELKRAFSTKHRMYSDYNQQDAQEFLRFFLDSLHSALNSGVKGE 641
Query: 457 YVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSI 516
+N IDD A W++ + +S++ DLFVG KSTL C C + S+
Sbjct: 642 TLN---------IDDNLSDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSV 692
Query: 517 TFDPYNDLTLPLP 529
TFDP+ DL++PLP
Sbjct: 693 TFDPFWDLSVPLP 705
Score = 97.4 bits (241), Expect = 1e-19
Identities = 52/151 (34%), Positives = 78/151 (51%), Gaps = 3/151 (1%)
Query: 900 SSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRS 959
S L++CL LF + E+L + C CK + +K + P L+IHLKRF R
Sbjct: 708 SRCKLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRFSETRW 767
Query: 960 FSDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDG 1019
K+ V+FP +++ N Y L A+ NH G GGHY A C++ +
Sbjct: 768 --SKLSNIVEFPTSDSELNMGSYGANSNSNVHYSLYAISNHMGSTAGGHYVALCKHPVSR 825
Query: 1020 KWYYFDDSRVNEVSPENS-IAGSAYLLFYRR 1049
KW+ F+D+ V++ EN ++ SAY+LFY R
Sbjct: 826 KWHEFNDNIVSDALSENHLVSSSAYILFYER 856
>7291841 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1096
Score = 120 bits (301), Expect = 1e-26
Identities = 80/268 (29%), Positives = 133/268 (48%), Gaps = 57/268 (21%)
Query: 835 EALDGTLHLKVSPLLDVHNAIICEWEAVKVINVFDEDNGVNWDHPAILENLSLSEVRKTR 894
E +D L + S H ++ EW + + + + + A++E+ S++ + ++
Sbjct: 464 EMIDMALSVLSSEAGPQHIKLLLEWSSPEAHFISKQQD----TEEAVVEHESVARLSASK 519
Query: 895 AQTEKSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRF 954
++ +++TL+ CL +++ E L + D+W CP+C+Q+ K + LW+ PDIL++H KRF
Sbjct: 520 P-SDTAALTLEQCLEHYTKAETLSAEDAWRCPHCQQYLPVVKTLGLWSLPDILVVHFKRF 578
Query: 955 ENQRS---FSDKIDATVKFPIEGLDMSPYLS---------------------------YK 984
+S + K+ VKFP+ DMSP+L+ +K
Sbjct: 579 RQHQSKGPQAAKLTTMVKFPLTAFDMSPHLARGVHESASSSLGMGTGIGLGLGLGSNPWK 638
Query: 985 K---------------EGENDVYDLIAVDNHYGG-LGGGHYTAYCRNFIDGKWYYFDDSR 1028
K + ++ YDL AV H G L GHYTA C+N D +WY FDD R
Sbjct: 639 KARSVDSRSSTLNSRCDAKDTRYDLYAVCYHQGDTLETGHYTAACKNPYDRQWYKFDDQR 698
Query: 1029 VNEVSPENSIA-----GSAYLLFYRRRT 1051
V++V PE+ I AY+LFY+RR+
Sbjct: 699 VSKV-PEDDIEQDIINNEAYMLFYQRRS 725
Score = 111 bits (278), Expect = 6e-24
Identities = 99/372 (26%), Positives = 169/372 (44%), Gaps = 63/372 (16%)
Query: 337 GIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPL-----GHKGDVAHA 391
G+MGL N GNTC+MN+ LQCL H L EYF+ Y+ ++ N + G KG++
Sbjct: 67 GVMGLKNHGNTCFMNAVLQCLSHTDILAEYFVLDQYKADLKRRNKINSRKFGTKGELTEQ 126
Query: 392 FGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNR 451
++L +L+ ++ +FK + Y + F Q D+QEFL +LLD +HEDLN
Sbjct: 127 LANVLKALWT---CKNESDHSTSFKAVVDRYGTQFRSSTQHDAQEFLFWLLDKVHEDLNT 183
Query: 452 VIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNC 511
++ Y K + G+ D+ V+ A + ++I + N+S + +F ++S+L CP C
Sbjct: 184 ASKRRY--KSLKNSYGRSDE----VIAAETLANHI-RCNNSFVQAVFQAQFRSSLTCPRC 236
Query: 512 NHVSITFDPYNDLTLPLPIENYWSTKVTI---------------FPQNSPPCTLEVELSK 556
S TFDP++ +++ LP + VT+ P SP L +L
Sbjct: 237 EKQSNTFDPFHCISVQLPQLTQQTIFVTVVYMTRLPRQVRMGLRVPAGSPIVALREQLQA 296
Query: 557 TSSYNDLKAYVAQHANMHANDLIGAEIFNHQFYNNYE----SNVEADY-------LPISE 605
+ + + + AE F FY+ S++E Y P+++
Sbjct: 297 DTGIEGSRMVLVD---------LNAEGFTRVFYDTQPVETLSSIETIYCIEVPAATPVAK 347
Query: 606 LISESDT---------VIFYEVHRGQDDLVVPILNT-RFEEGFKTPRLFGYPFFIALSQA 655
+ S+T + Q DL++ + N R ++G R FG PF ++
Sbjct: 348 AATPSETGDKSAPTAVTPSPAAAQSQADLLLLVANVYRAKDGADITR-FGAPF--SMKAP 404
Query: 656 EQFSYGAIRKKI 667
SY ++K++
Sbjct: 405 RDCSYQDLQKRM 416
>Hs6912742 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 565
Score = 118 bits (296), Expect = 5e-26
Identities = 75/240 (31%), Positives = 123/240 (51%), Gaps = 21/240 (8%)
Query: 313 VKQKSSNQHWPSNFFHYNKLNAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGY 372
+ +SS + + ++ L SG +GL NLGNTC++N+ LQCL L ++ L + +
Sbjct: 186 ISARSSEPFYSDDKMAHHTLLLGSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDF 245
Query: 373 EREININNPLGHKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQ 432
+E+ G ++ AF ++ +L+ P ++ P F+ Y F+GY QQ
Sbjct: 246 RQEVPGG---GRAQELTEAFADVIGALWHPDSCEAV--NPTRFRAVFQKYVPSFSGYSQQ 300
Query: 433 DSQEFLAFLLDGLHEDLNR--------VIEKPYVNKPE----FPNDGQIDDTDQIVLLAA 480
D+QEFL L++ LH ++NR + P + P + ++ D D+ L
Sbjct: 301 DAQEFLKLLMERLHLEINRRGRRAPPILANGPVPSPPRRGGALLEEPELSDDDRANL--- 357
Query: 481 NMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLPIENYWSTKVTI 540
MW +R DS I+DLFVG KS L C C + S TF+ + DL+LP+P + + KV++
Sbjct: 358 -MWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSL 416
Score = 97.4 bits (241), Expect = 1e-19
Identities = 56/148 (37%), Positives = 85/148 (56%), Gaps = 6/148 (4%)
Query: 902 ITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFS 961
++L C LF++ E L S ++ C C+Q T+++K++ + P IL++HL RF R
Sbjct: 414 VSLRDCFNLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRGSI 473
Query: 962 DKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKW 1021
K V FP++ L + + S K + VY L A+ NH G + GHYTA CR W
Sbjct: 474 KKSSVGVDFPLQRLSLGDFASDK--AGSPVYQLYALCNHSGSVHYGHYTALCR--CQTGW 529
Query: 1022 YYFDDSRVNEVSPENSIAGS-AYLLFYR 1048
+ ++DSRV+ VS EN +A S Y+LFY+
Sbjct: 530 HVYNDSRVSPVS-ENQVASSEGYVLFYQ 556
>Hs21265129 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 551
Score = 118 bits (296), Expect = 5e-26
Identities = 75/240 (31%), Positives = 123/240 (51%), Gaps = 21/240 (8%)
Query: 313 VKQKSSNQHWPSNFFHYNKLNAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGY 372
+ +SS + + ++ L SG +GL NLGNTC++N+ LQCL L ++ L + +
Sbjct: 186 ISARSSEPFYSDDKMAHHTLLLGSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDF 245
Query: 373 EREININNPLGHKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQ 432
+E+ G ++ AF ++ +L+ P ++ P F+ Y F+GY QQ
Sbjct: 246 RQEVPGG---GRAQELTEAFADVIGALWHPDSCEAV--NPTRFRAVFQKYVPSFSGYSQQ 300
Query: 433 DSQEFLAFLLDGLHEDLNR--------VIEKPYVNKPE----FPNDGQIDDTDQIVLLAA 480
D+QEFL L++ LH ++NR + P + P + ++ D D+ L
Sbjct: 301 DAQEFLKLLMERLHLEINRRGRRAPPILANGPVPSPPRRGGALLEEPELSDDDRANL--- 357
Query: 481 NMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLPIENYWSTKVTI 540
MW +R DS I+DLFVG KS L C C + S TF+ + DL+LP+P + + KV++
Sbjct: 358 -MWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSL 416
Score = 82.0 bits (201), Expect = 5e-15
Identities = 52/148 (35%), Positives = 78/148 (52%), Gaps = 20/148 (13%)
Query: 902 ITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFS 961
++L C LF++ E L S ++ C C+Q T+++K++ + P IL++HL RF R
Sbjct: 414 VSLRDCFNLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRGSI 473
Query: 962 DKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKW 1021
K V FP++ L + + S K A HY GHYTA CR W
Sbjct: 474 KKSSVGVDFPLQRLSLGDFASDK-----------AGSVHY-----GHYTALCR--CQTGW 515
Query: 1022 YYFDDSRVNEVSPENSIAGS-AYLLFYR 1048
+ ++DSRV+ VS EN +A S Y+LFY+
Sbjct: 516 HVYNDSRVSPVS-ENQVASSEGYVLFYQ 542
>YER144c [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 805
Score = 117 bits (293), Expect = 1e-25
Identities = 72/197 (36%), Positives = 104/197 (52%), Gaps = 6/197 (3%)
Query: 338 IMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLLY 397
I+GL N+GN CYMN LQCL+ +L FL Y IN ++ G KG +A F L+
Sbjct: 445 IVGLENIGNCCYMNCILQCLVGTHDLVRMFLDNTYLNFINFDSSRGSKGLLAKNFAILVN 504
Query: 398 SL-----FAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRV 452
++ F P ++ FK GH N +++ QQD QEF FLLDGLHEDLN+
Sbjct: 505 NMHRHGAFTPPNVRTIPVQTIQFKKICGHINPMYSDSMQQDCQEFCQFLLDGLHEDLNQN 564
Query: 453 IEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCN 512
K ++ K + ++ + I +A W+ + S I+DLF G Y S L C C
Sbjct: 565 GSKKHL-KQLSDEEERMREKMSIRKASALEWERFLLTDFSAIIDLFQGQYASRLQCQVCE 623
Query: 513 HVSITFDPYNDLTLPLP 529
H S T+ ++ L++P+P
Sbjct: 624 HTSTTYQTFSVLSVPVP 640
Score = 87.8 bits (216), Expect = 1e-16
Identities = 56/158 (35%), Positives = 80/158 (50%), Gaps = 19/158 (12%)
Query: 907 CLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSDKIDA 966
C R F++ E LG + W CP C + ++KQ+++ P L+I+LKRF+NQ +K +
Sbjct: 650 CFREFTKCERLGVDEQWSCPKCLKKQPSTKQLKITRLPKKLIINLKRFDNQ---MNKNNV 706
Query: 967 TVKFPIEGLDMSPYLSYKKEGENDV--------------YDLIAVDNHYGGLGGGHYTAY 1012
V++P LD++PY + E V Y L V H G L GGHYT+Y
Sbjct: 707 FVQYPY-SLDLTPYWARDFNHEAIVNEDIPTRGQVPPFRYRLYGVACHSGSLYGGHYTSY 765
Query: 1013 CRNFIDGKWYYFDDSRVNEVS-PENSIAGSAYLLFYRR 1049
WY+FDDS ++ I SAY+LFY R
Sbjct: 766 VYKGPKKGWYFFDDSLYRPITFSTEFITPSAYVLFYER 803
>7300711 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 888
Score = 115 bits (289), Expect = 3e-25
Identities = 68/197 (34%), Positives = 99/197 (49%), Gaps = 20/197 (10%)
Query: 333 NAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF 392
N G+ GL NLGNTCYMNS LQCL + P+L EY + Y+ I+ +N G V
Sbjct: 549 NVGRGLTGLKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNKT--NGQVIEEV 606
Query: 393 GHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRV 452
L+ L+ GQ A R+ + +G Y +F G QQDS EFL L+D LH DL +
Sbjct: 607 AALIKELW---NGQYKCVASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDLQTL 663
Query: 453 IEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCN 512
+ +++ + W K +S+I+ LF G KST+ C C+
Sbjct: 664 ---------------HVPRQREMISASEKAWLEFTKAKESMILHLFYGQMKSTVKCVACH 708
Query: 513 HVSITFDPYNDLTLPLP 529
S T++ +++L+L LP
Sbjct: 709 KESATYESFSNLSLELP 725
Score = 112 bits (281), Expect = 3e-24
Identities = 56/150 (37%), Positives = 89/150 (59%), Gaps = 10/150 (6%)
Query: 904 LDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRF----ENQRS 959
L+ C+ ++ E + W CP+CK A K++++ P +L++HLKRF N S
Sbjct: 733 LNQCMDMYFSGERI---HGWNCPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADPSNSGS 789
Query: 960 FSDKIDATVKFPIEGLDMSPYLSYKKEGE--NDVYDLIAVDNHYGGLGGGHYTAYCRNFI 1017
+ K + ++FP+E LDM+PY++ + Y L AV NHYG + GGHYTA+C++
Sbjct: 790 YMKKQNY-LRFPLENLDMNPYIARAESRAVTPKTYQLYAVSNHYGTMEGGHYTAFCKSAN 848
Query: 1018 DGKWYYFDDSRVNEVSPENSIAGSAYLLFY 1047
GKW+ FDD V+ + N ++ +AY+LFY
Sbjct: 849 YGKWFKFDDQVVSALDSSNVVSSAAYILFY 878
>HsM7706755 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 381
Score = 113 bits (283), Expect = 2e-24
Identities = 74/238 (31%), Positives = 120/238 (50%), Gaps = 21/238 (8%)
Query: 313 VKQKSSNQHWPSNFFHYNKLNAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGY 372
+ +SS + + ++ L SG +GL NLGNTC++N+ LQCL L ++ L + +
Sbjct: 2 ISARSSEPFYSDDKMAHHTLLLGSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDF 61
Query: 373 EREININNPLGHKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQ 432
+E+ G ++ AF ++ +L+ ++ P F+ Y F+GY QQ
Sbjct: 62 RQEVPGG---GRAQELTEAFADVIGALWHLDSCEAV--NPTRFRAVFQKYVPSFSGYSQQ 116
Query: 433 DSQEFLAFLLDGLHEDLNR--------VIEKPYVNKPE----FPNDGQIDDTDQIVLLAA 480
D+QEFL L++ LH ++NR + P + P + ++ D D+ L
Sbjct: 117 DAQEFLKLLMERLHLEINRRGRRAPPILANGPVPSPPRRGGALLEEPELSDDDRANL--- 173
Query: 481 NMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLPIENYWSTKV 538
MW +R DS I+DLFVG KS L C C + S TF+ + DL+LP+P + + KV
Sbjct: 174 -MWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKV 230
Score = 96.3 bits (238), Expect = 3e-19
Identities = 56/148 (37%), Positives = 84/148 (55%), Gaps = 6/148 (4%)
Query: 902 ITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFS 961
+ L C LF++ E L S ++ C C+Q T+++K++ + P IL++HL RF R
Sbjct: 230 VFLRDCFNLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRGSI 289
Query: 962 DKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKW 1021
K V FP++ L + + S K + VY L A+ NH G + GHYTA CR W
Sbjct: 290 KKSSVGVDFPLQRLSLGDFASDK--AGSPVYQLYALCNHSGSVHYGHYTALCR--CQTGW 345
Query: 1022 YYFDDSRVNEVSPENSIAGS-AYLLFYR 1048
+ ++DSRV+ VS EN +A S Y+LFY+
Sbjct: 346 HVYNDSRVSPVS-ENQVASSEGYVLFYQ 372
>Hs5730110 [O] KOG1867 Ubiquitin-specific protease
Length = 521
Score = 113 bits (282), Expect = 2e-24
Identities = 69/200 (34%), Positives = 108/200 (53%), Gaps = 19/200 (9%)
Query: 853 NAIICEWEAVKVINVFDEDNGVNWDHPAILENLSLSEVRKTRAQTEKSS--ITLDSCLRL 910
N +IC E+ K FD ++ D P S+ R R++ +++ +L CLR
Sbjct: 324 NCLICGTESRK----FDPFLDLSLDIP--------SQFRSKRSKNQENGPVCSLRDCLRS 371
Query: 911 FSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSDKIDATVKF 970
F+ E L + + C CK+ +++K+ + P +L +HLKRF +K+D V+F
Sbjct: 372 FTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEF 431
Query: 971 PIEGLDMSPYLSYKKEG--ENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKWYYFDDS 1027
P+ GLDM YL + E+ +YDL AV H+G G+G GHYTAY + +G+W++F+DS
Sbjct: 432 PLRGLDMKWYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATH--EGRWFHFNDS 489
Query: 1028 RVNEVSPENSIAGSAYLLFY 1047
V E + AY+LFY
Sbjct: 490 TVTLTDEETVVKAKAYILFY 509
>SPBC18H10.08c [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 438
Score = 112 bits (280), Expect = 4e-24
Identities = 73/194 (37%), Positives = 103/194 (52%), Gaps = 10/194 (5%)
Query: 339 MGLSNLGNTCYMNSALQCLLHIPELNEYFLY-KGYEREININNPLGHKGDVAHAFGHLLY 397
+GL+NLGNTCYMN LQCL +L L +G + IN NPLG G + AF LL
Sbjct: 72 IGLTNLGNTCYMNCVLQCLFACKDLTIPMLQGRGLLQNINTKNPLGTGGKITSAFFSLLQ 131
Query: 398 SLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPY 457
S+ ++GQ + +PRNF + N F+ GQ D+QEFL F LD LHEDLN +
Sbjct: 132 SVLL-NHGQRSI-SPRNFLEIVQSLNRDFSIDGQCDAQEFLNFFLDKLHEDLNSNASR-- 187
Query: 458 VNKPEFP-NDGQIDDTDQIVL--LAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHV 514
P P + Q+ +++ L + W+ + N S++++ FVG S C C
Sbjct: 188 --SPIAPLTEDQLSAREELPLSHFSHIEWNLHLRSNKSIVVNNFVGQLCSRTQCMTCGRT 245
Query: 515 SITFDPYNDLTLPL 528
S TF P+ L +P+
Sbjct: 246 STTFAPFTSLAIPI 259
Score = 74.7 bits (182), Expect = 8e-13
Identities = 48/154 (31%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Query: 902 ITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFS 961
++L CL FS PE+L D W+CP CK A K I + P+ L+I ++RF+
Sbjct: 266 VSLQECLLKFSAPELLQGHDGWHCPVCKVQRSAKKVIMISKLPEYLIIQIQRFKISVMGR 325
Query: 962 DKIDATVKFPIEGLDMSPYLSYKKEGENDV---YDLIAVDNHYGGLGGGHYTAYCRNFID 1018
KID + ++ + G + Y+L A HYG L GHY + +
Sbjct: 326 KKIDTPLGLSLQIPSKMLVPPSFQSGIGYIPSNYNLFAFICHYGQLENGHYISDV--LFN 383
Query: 1019 GKWYYFDDSRVNEVSPENSIA---GSAYLLFYRR 1049
+W + DDS V V + S+Y+LFY+R
Sbjct: 384 NEWCHIDDSIVRTVGGITDLREDFSSSYILFYKR 417
>At2g24640 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 743
Score = 106 bits (265), Expect = 2e-22
Identities = 101/351 (28%), Positives = 158/351 (44%), Gaps = 41/351 (11%)
Query: 901 SITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSF 960
+++L+ CL F+ E L + + C C + +A K++ + P+IL I LKRF+ R
Sbjct: 386 AVSLEECLDQFTAKEWLQGDNLYKCDRCDDYVKACKRLSIRCAPNILTIALKRFQGGR-- 443
Query: 961 SDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGG---GHYTAYCRNFI 1017
K++ + FP E D+ PY+S EG +DVY L AV H L GHY Y ++F
Sbjct: 444 FGKLNKRISFP-ETFDLGPYMSGGGEG-SDVYKLYAVIVHLDMLNASFFGHYICYVKDF- 500
Query: 1018 DGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRRTSGNQTLGNGKLRDIIDI--------- 1068
G WY DDS V +V E+ ++ AY+L Y R L G L D DI
Sbjct: 501 RGNWYRIDDSEVEKVELEDVLSQRAYMLLYSR-----TVLSEGALTD-YDIWYWCRVQPR 554
Query: 1069 -SRKEYEQKQDEFMTNVETLYAATHTDTESEAS-----DSDRSSVDEEMDSDNSDCENDK 1122
S E+ QDE T +TL ++ D E+S D+ SS+ + S + D E +K
Sbjct: 555 PSNLRSEESQDEKKT--DTLNTESNQDGSVESSGVGTNDTSVSSLCNGIISHSEDPEYEK 612
Query: 1123 KSAFVDQSDISSN----SLGMDNLTYSNRPSKD-----NTIHTSKNANGSIESTLNNNEL 1173
+S+ +S + +D + + S D T H + ANG + T+ N +
Sbjct: 613 ESSLSASVPVSEEGKEVDVKVDTVDSESNRSIDMEHDSGTDHQEEEANGKEDPTVENLAV 672
Query: 1174 PEAEQTVTATERKGALQYNVSSLEVGSNIAK-LDTHDSSRRKLRLLDKIYL 1223
+ +T A ++ E +K L+ S + L+K +L
Sbjct: 673 DSSCLDITTPSPSAATEFIPQENERSDTESKPLEKEHSDTESNKPLEKEHL 723
>7293885 [O] KOG1867 Ubiquitin-specific protease
Length = 735
Score = 105 bits (261), Expect = 6e-22
Identities = 65/180 (36%), Positives = 93/180 (51%), Gaps = 7/180 (3%)
Query: 872 NGVNWDHPAILE-NLSLSEVRKTRAQTEKSSITLDSCLRLFSQPEILGSADSWYCPNCKQ 930
NGV+ + + +L L E T K TL CL +++ E LGSA C CK
Sbjct: 555 NGVSTTYDPFWDISLDLGETTTHGGVTPK---TLIDCLERYTRAEHLGSAAKIKCSTCKS 611
Query: 931 HTQASKQIELWNTPDILLIHLKRFENQRSFSDKIDATVKFPIEGLDMSPYLSYKKEGEND 990
+ +++KQ L P ++ HLKRFE+ KI + ++FP+E DM+P++S KK D
Sbjct: 612 YQESTKQFSLRTLPSVVSFHLKRFEHSALIDRKISSFIQFPVE-FDMTPFMSEKKNAYGD 670
Query: 991 V-YDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRR 1049
+ L AV NH G + GHYTAY R+ D W DD + S + + YLLFY +
Sbjct: 671 FRFSLYAVVNHVGTIDTGHYTAYVRHQKD-TWVKCDDHVITMASLKQVLDSEGYLLFYHK 729
Score = 76.3 bits (186), Expect = 3e-13
Identities = 56/197 (28%), Positives = 95/197 (47%), Gaps = 17/197 (8%)
Query: 333 NAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF 392
N G+ GL NLG TC+MN +Q L+H P L++YF+ ++ + HK V
Sbjct: 391 NQTIGLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHD----CGSKSSHKCLVCE-- 444
Query: 393 GHLLYSLFAPSY-GQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNR 451
+ LF Y G + + + I ++ AGY QQD+ EF LD LH
Sbjct: 445 ---VSRLFQEFYSGSRSPLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLH---RH 498
Query: 452 VIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNC 511
++ ++ + + G T+ +++ + + + +I +F G+ +S +VC C
Sbjct: 499 CVKAKAEHESKSNSSGSGSGTNSSNSSSSHCYG----QCNCIIDQIFTGMLQSDVVCQAC 554
Query: 512 NHVSITFDPYNDLTLPL 528
N VS T+DP+ D++L L
Sbjct: 555 NGVSTTYDPFWDISLDL 571
>Hs22065367 [O] KOG1867 Ubiquitin-specific protease
Length = 525
Score = 104 bits (260), Expect = 8e-22
Identities = 57/162 (35%), Positives = 87/162 (53%), Gaps = 16/162 (9%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
TL CLR F++PE LGS+ C C + +++KQ+ + P + HLKRFE+
Sbjct: 361 TLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRR 420
Query: 963 KIDATVKFPIEGLDMSPYLSYKKE--------------GENDVYDLIAVDNHYGGLGGGH 1008
KI V FP+E LDM+P+++ KE ++ Y L AV NH G L GH
Sbjct: 421 KITTYVSFPLE-LDMTPFMASSKESRMNGQYQQPTDSLNNDNKYSLFAVVNHQGTLESGH 479
Query: 1009 YTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRR 1050
YT++ R D +W+ DD+ + + S ++ + YLLFY ++
Sbjct: 480 YTSFIRQHKD-QWFKCDDAIITKASIKDVLDSEGYLLFYHKQ 520
Score = 74.7 bits (182), Expect = 8e-13
Identities = 57/198 (28%), Positives = 80/198 (39%), Gaps = 36/198 (18%)
Query: 333 NAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF 392
N G+ GL NLGNTC+MN +Q L H P L ++FL + E+ +
Sbjct: 170 NCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHRCEMQ---------SPSSCL 220
Query: 393 GHLLYSLFAPSY-GQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNR 451
+ SLF Y G + + P + + + AGY QQD+ EFL LD LH
Sbjct: 221 VCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKG 280
Query: 452 VIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNC 511
N P N +I +F G +S + C C
Sbjct: 281 DDNGKKANNPNHCN--------------------------CIIDQIFTGGLQSDVTCQVC 314
Query: 512 NHVSITFDPYNDLTLPLP 529
+ VS T DP+ D++L LP
Sbjct: 315 HGVSTTIDPFWDISLDLP 332
>CE26210 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 357
Score = 103 bits (257), Expect = 2e-21
Identities = 59/151 (39%), Positives = 76/151 (50%), Gaps = 2/151 (1%)
Query: 900 SSITLDSCLRL-FSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQR 958
SS +LD CLR FSQ ++ G + W CP CK+ +++ +LW P +++IHLKRF
Sbjct: 207 SSCSLDMCLRSHFSQTKLDGDS-RWNCPKCKEPRASTRTSKLWQPPPVMIIHLKRFALFN 265
Query: 959 SFSDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFID 1018
+K A V F D+ PYL E VY L A H G L GHYTA +
Sbjct: 266 GDFEKNTAAVTFETARFDVRPYLHEMAPAEKPVYKLYAATLHNGRLNSGHYTAVASHLRS 325
Query: 1019 GKWYYFDDSRVNEVSPENSIAGSAYLLFYRR 1049
KW FDDS V AY+LFY+R
Sbjct: 326 DKWLRFDDSVVTPCENFKVDPSLAYILFYKR 356
Score = 76.3 bits (186), Expect = 3e-13
Identities = 61/205 (29%), Positives = 90/205 (43%), Gaps = 20/205 (9%)
Query: 330 NKLNAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVA 389
NK G +GL N+GNTC+M++ LQCL P L E F K + ++N + LG KG ++
Sbjct: 15 NKGRGVPGAVGLFNMGNTCFMSATLQCLFQTPGLAEVFTKKVFVSKVNTQSRLGSKGVIS 74
Query: 390 HAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGH--YNSLFAGYGQQDSQEFLAFLLDGLHE 447
F L ++ G T P F Y L G Q D+ EF FLLD LHE
Sbjct: 75 AGFASLSDMIW---NGTFTAIRPSRFLQLFSDTVYQPLSDG-RQHDASEFQIFLLDALHE 130
Query: 448 DLNRVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRND---SVIMDLFVGLYKS 504
D N+ ++ + G +A D++KK S + L + S
Sbjct: 131 DTNQA-QRISFEQNYHGGAG----------IAKEAADFLKKHYQFSLSPVNRLLGSITVS 179
Query: 505 TLVCPNCNHVSITFDPYNDLTLPLP 529
+ C C S TF+ +++ +P
Sbjct: 180 EIRCLTCGASSATFEENTIISVEIP 204
>CE29636 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1119
Score = 102 bits (254), Expect = 4e-21
Identities = 57/150 (38%), Positives = 83/150 (55%), Gaps = 8/150 (5%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFE--NQRSF 960
+L+ C+ FS PE L +A C C++ T K + +W P L+IHLKRFE ++
Sbjct: 973 SLEHCIEKFSCPETLDAAIQ--CDRCEKKTMRDKVMTIWKLPKYLIIHLKRFEFLREQGR 1030
Query: 961 SDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGK 1020
K TV FP++ D +P++ + + + Y+ IA+ NHYG L GH+ AY ++ D K
Sbjct: 1031 MGKCKRTVNFPLKHFDPAPFVD---KPDGNTYECIALANHYGQLSCGHFIAYAKSNED-K 1086
Query: 1021 WYYFDDSRVNEVSPENSIAGSAYLLFYRRR 1050
W +D V EVS E AYLLFY R+
Sbjct: 1087 WLLLNDCSVREVSEEEVDKQGAYLLFYERK 1116
>CE29635 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1116
Score = 102 bits (254), Expect = 4e-21
Identities = 57/150 (38%), Positives = 83/150 (55%), Gaps = 8/150 (5%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFE--NQRSF 960
+L+ C+ FS PE L +A C C++ T K + +W P L+IHLKRFE ++
Sbjct: 970 SLEHCIEKFSCPETLDAAIQ--CDRCEKKTMRDKVMTIWKLPKYLIIHLKRFEFLREQGR 1027
Query: 961 SDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGK 1020
K TV FP++ D +P++ + + + Y+ IA+ NHYG L GH+ AY ++ D K
Sbjct: 1028 MGKCKRTVNFPLKHFDPAPFVD---KPDGNTYECIALANHYGQLSCGHFIAYAKSNED-K 1083
Query: 1021 WYYFDDSRVNEVSPENSIAGSAYLLFYRRR 1050
W +D V EVS E AYLLFY R+
Sbjct: 1084 WLLLNDCSVREVSEEEVDKQGAYLLFYERK 1113
>Hs22055583 [O] KOG1867 Ubiquitin-specific protease
Length = 800
Score = 101 bits (252), Expect = 6e-21
Identities = 55/161 (34%), Positives = 90/161 (55%), Gaps = 15/161 (9%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
+L CL+ F++PE LGS+ C +C+ + +++KQ+ + P + HLKRFE+
Sbjct: 637 SLTDCLQWFTRPEHLGSSAKIKCNSCQSYQESTKQLTMKKLPIVACFHLKRFEHVGKQRR 696
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEG-------------ENDVYDLIAVDNHYGGLGGGHY 1009
KI+ + FP+E LDM+P+L+ KE + Y L AV NH+G L GHY
Sbjct: 697 KINTFISFPLE-LDMTPFLASTKESRMKEGQPPTDCVPNENKYSLFAVINHHGTLESGHY 755
Query: 1010 TAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRR 1050
T++ R D +W+ DD+ + + + E+ + YLLFY ++
Sbjct: 756 TSFIRQQKD-QWFSCDDAIITKATIEDLLYSEGYLLFYHKQ 795
Score = 76.3 bits (186), Expect = 3e-13
Identities = 60/193 (31%), Positives = 83/193 (42%), Gaps = 34/193 (17%)
Query: 337 GIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLL 396
G+ GL NLGNTC+MN +Q L HIP L ++FL + I + L +++ F H +
Sbjct: 450 GLRGLINLGNTCFMNCIVQALTHIPLLKDFFL-SDKHKCIMTSPSLCLVCEMSSLF-HAM 507
Query: 397 YSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKP 456
YS G T + P + I + AGY QQD+ EFL +LD LH
Sbjct: 508 YS------GSRTPHIPYKLLHLIWIHAEHLAGYRQQDAHEFLIAILDVLHRHSKDDSGGQ 561
Query: 457 YVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSI 516
N P N +I +F G +S + C C+ VS
Sbjct: 562 EANNPNCCN--------------------------CIIDQIFTGGLQSDVTCQACHSVST 595
Query: 517 TFDPYNDLTLPLP 529
T DP D++L LP
Sbjct: 596 TIDPCWDISLDLP 608
>Hs22056581 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 493
Score = 101 bits (251), Expect = 8e-21
Identities = 45/109 (41%), Positives = 68/109 (62%), Gaps = 1/109 (0%)
Query: 939 ELWNTPDILLIHLKRFENQRSFSDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVD 998
E+W P +LL+HLK F + K+ +V FP+E L +S Y+ K + Y+L +V
Sbjct: 381 EIWKLPPVLLVHLKHFSYNGRWKQKLQTSVDFPLENLALSQYVIGPKNNLKN-YNLFSVS 439
Query: 999 NHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFY 1047
+H GGL GGHYTAYC+N +W+ FDD V+++S + + +AY+LFY
Sbjct: 440 DHCGGLDGGHYTAYCKNAAKQRWFKFDDHEVSDISVSSVKSSAAYILFY 488
Score = 75.1 bits (183), Expect = 7e-13
Identities = 58/174 (33%), Positives = 85/174 (48%), Gaps = 22/174 (12%)
Query: 383 GHKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLL 442
GHKG+VA FG ++ AP GQ + +P++ K TIG N FAGY Q DSQEF FL+
Sbjct: 267 GHKGEVAEEFGIIMK---APWTGQYRYISPKDLKVTIGKINYQFAGYSQ-DSQEFFLFLM 322
Query: 443 DGLHEDLNRVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVG-- 500
DGL EDLN+ + + N+ ++D A + W K+ +S+I+ LF
Sbjct: 323 DGLREDLNKTDNRKTYKE---ENNDHLND----FKAAEHAWQKHKRLYESIIVALFQELD 375
Query: 501 --LYKSTLVCPNCNHVSITFDPYN-------DLTLPLPIENYWSTKVTIFPQNS 545
L K P V + YN ++ P+EN ++ I P+N+
Sbjct: 376 GILKKEIWKLPPVLLVHLKHFSYNGRWKQKLQTSVDFPLENLALSQYVIGPKNN 429
>ECU06g0910 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 726
Score = 98.2 bits (243), Expect = 7e-20
Identities = 65/228 (28%), Positives = 105/228 (45%), Gaps = 29/228 (12%)
Query: 338 IMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLLY 397
+ GL N GNTC+MNS LQCL++ +L+EYF+ + YE +N + + +A A+ Y
Sbjct: 229 VRGLRNQGNTCFMNSGLQCLMNCWKLSEYFISREYEESLNRHKAI--HASLASAY----Y 282
Query: 398 SLFAPSY-GQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKP 456
L + Y G P + ++G + G +QDS EF+ +LD LHE L+ P
Sbjct: 283 DLISQVYDGNLHAITPVGIRKSLGSIYEEYKGNDEQDSVEFITKMLDTLHEALSTQSSHP 342
Query: 457 YVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSI 516
+ E W++ N S+I DLF KSTL C C +
Sbjct: 343 KKKEKE------------------KWWEH----NRSIITDLFFFCLKSTLTCRGCGSTKV 380
Query: 517 TFDPYNDLTLPLPIENYWSTKVTIFPQNSPPCTLEVELSKTSSYNDLK 564
+ +P L+LP+P + +F ++ +++ ++S LK
Sbjct: 381 SIEPAVCLSLPIPRSMQHKDNIVVFYESGRRQPVKIYADASTSIRGLK 428
Score = 58.2 bits (139), Expect = 8e-08
Identities = 44/152 (28%), Positives = 69/152 (44%), Gaps = 23/152 (15%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
TL C+ F + E L ++ +C C SK+++L + P L+I LKRF+ S
Sbjct: 591 TLQHCVNRFLEKEDLHPSERLHCEGCNGKMMFSKKMDLEDLPMYLIIQLKRFQYVNSSPM 650
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGG--LGGGHYTAYCRNFIDGK 1020
KI +++P++ ++ Y +I V NH GHY +Y R
Sbjct: 651 KISTLIEYPLDKFLLN----------GVEYMVIGVCNHDSDAVTSSGHYVSYLRK---NG 697
Query: 1021 WYYFDD---SRVNEVSPENSIAGSAYLLFYRR 1049
WY +D RV+EV E++ Y+LF R
Sbjct: 698 WYLCNDQKIERVDEVDKEHT-----YVLFLER 724
>At5g65450 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 731
Score = 94.4 bits (233), Expect = 1e-18
Identities = 66/229 (28%), Positives = 112/229 (48%), Gaps = 25/229 (10%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
+L+ L F+ E+L + ++C CK + +A K++ + P+IL + LKRF++
Sbjct: 487 SLEEALAQFTAYEVLDGENRYFCGRCKSYQKAKKKLMILEGPNILTVVLKRFQSDN--FG 544
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLG---GGHYTAYCRNFIDG 1019
K+ + FP E LD+SPY+S G++ VY L AV H + GHY Y + +DG
Sbjct: 545 KLSKPIHFP-ELLDISPYMSDPNHGDHPVYSLYAVVVHLDAMSTLFSGHYVCYIKT-LDG 602
Query: 1020 KWYYFDDSRVNEVSPENSIAGSAYLLFYRRRT----SGNQTLGNGKLRDIIDISRKEYEQ 1075
W+ DDS V V E + AY+L Y R + S N + + R++ I ++ +
Sbjct: 603 DWFKIDDSNVFPVQLETVLLEGAYMLLYARDSPRPVSKNGGRKSKQRRNLAAIPSRKGNK 662
Query: 1076 KQDEFMTN------------VETLYAATHTDTESEASDSDRSSVDEEMD 1112
KQ + N + +++++ +DT S S D S ++ D
Sbjct: 663 KQRDGDNNSLLPRVDWSSGSLSSMFSS--SDTTSSCSTKDSSGIENLSD 709
>At5g10790 [O] KOG1867 Ubiquitin-specific protease
Length = 557
Score = 94.4 bits (233), Expect = 1e-18
Identities = 61/174 (35%), Positives = 87/174 (49%), Gaps = 28/174 (16%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQ--RSF 960
TL CL F++ E LG C +C + ++SKQ+ + P +L +H+KRFE+ R
Sbjct: 362 TLSGCLDFFTRSEKLGPDQKLNCQSCGEKRESSKQMSIRRLPLLLCLHVKRFEHSLTRKT 421
Query: 961 SDKIDATVKFPIEGLDMSPYLS--------------YKKEGEND---------VYDLIAV 997
S KID+ +++P L+MSPYLS + EGE D +++ AV
Sbjct: 422 SRKIDSYLQYPFR-LNMSPYLSSSIIGKRFGNRIFAFDGEGEYDSSSSSSPSAEFEIFAV 480
Query: 998 DNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
H G L GHY Y R + G WY DD+ +NEV E Y+LFY + T
Sbjct: 481 VTHKGMLESGHYVTYLR--LKGLWYRCDDAWINEVEEEVVRGCECYMLFYAQET 532
Score = 77.4 bits (189), Expect = 1e-13
Identities = 58/206 (28%), Positives = 91/206 (44%), Gaps = 34/206 (16%)
Query: 331 KLNAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAH 390
K P G+ GL+NLG+TC+MN+ LQ L+H P L ++L + R++ +G
Sbjct: 169 KWTFPLGLRGLNNLGSTCFMNAVLQALVHAPPLRNFWLSGQHNRDLCPRRTMG-----LL 223
Query: 391 AFGHLLYSLFAPSY-GQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDL 449
L +F+ + G T Y+P + + +++ A Y QQDS EF LLD +HE
Sbjct: 224 CLPCDLDVIFSAMFSGDRTPYSPAHLLYSWWQHSTNLATYEQQDSHEFFISLLDRIHE-- 281
Query: 450 NRVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCP 509
N+G+ Q + + F GL +S + C
Sbjct: 282 ---------------NEGKSKCLYQ-----------DNEECQCITHKAFSGLLRSDVTCT 315
Query: 510 NCNHVSITFDPYNDLTLPLPIENYWS 535
C S T+DP+ D++L L N +S
Sbjct: 316 TCGSTSTTYDPFIDISLTLDSMNGFS 341
>At4g24560 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 1008
Score = 93.2 bits (230), Expect = 2e-18
Identities = 58/152 (38%), Positives = 82/152 (53%), Gaps = 9/152 (5%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
TLD LR F++ EIL + + C +CK + +A K++++ P++L I LKRF Q
Sbjct: 703 TLDDALRRFTRTEILDGENKYRCGSCKSYERAKKKLKITEPPNVLTIALKRF--QAGKFG 760
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLG---GGHYTAYCRNFIDG 1019
K++ ++FP E LD++PY+S E +D Y L V H + GHY Y RN
Sbjct: 761 KLNKLIRFP-ETLDLAPYVSGGSEKSHD-YKLYGVIVHLDVMNAAFSGHYVCYIRN--QN 816
Query: 1020 KWYYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
KWY DDS V E + AY+LFY R T
Sbjct: 817 KWYKADDSTVVTSDVERILTKGAYMLFYARCT 848
>Hs14776897 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 372
Score = 92.8 bits (229), Expect = 3e-18
Identities = 58/163 (35%), Positives = 79/163 (47%), Gaps = 17/163 (10%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
TL+ L F QP L S +C NC + T+ + ++L + P L IHL RF + S +
Sbjct: 208 TLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTR 267
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEG------ENDVYDLIAVDNHYGGLGGGHYTAYCRNF 1016
KI ++ FP + LD S L K+E Y+L AV H G GHY Y RN
Sbjct: 268 KICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNA 326
Query: 1017 IDGKWYYFDDSRVNEVS----------PENSIAGSAYLLFYRR 1049
+DGKW+ F+DS + VS P +AYLL Y +
Sbjct: 327 VDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMK 369
>At4g31670 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 631
Score = 92.8 bits (229), Expect = 3e-18
Identities = 79/272 (29%), Positives = 125/272 (45%), Gaps = 22/272 (8%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
+L+ CL F+ E L + + C C + +A K++ + P+IL I LKR++ R
Sbjct: 329 SLEECLDQFTAEEWLHGDNMYKCDRCSDYVKACKRLTIRRAPNILTIALKRYQGGR--YG 386
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGG---GHYTAYCRNFIDG 1019
K++ + FP E LD++PY+S +G +DVY L AV H L GHY Y ++F G
Sbjct: 387 KLNKRISFP-ETLDLNPYMSEGGDG-SDVYKLYAVIVHLDMLNASFFGHYICYIKDFC-G 443
Query: 1020 KWYYFDDSRVNEVSPENSIAGSAYLLFYRR---RTSGN---QTLGNGKLRDIIDISRKEY 1073
WY DDS + V E+ ++ AY+L Y R R+S + + + K D +D
Sbjct: 444 NWYRIDDSEIESVELEDVLSQRAYMLLYSRIQARSSSSCLRSEVKDEKKTDTLDTESCVK 503
Query: 1074 EQKQDEFMTNVETLYAATHTDTESEASDSDRSSVDEEMDSDNSDCENDKKSAFVDQSDIS 1133
E + + +E+ ++TH E + S S + S V S+
Sbjct: 504 ELVESSMVGAIES-RSSTHATIEDPVCEQSPSP-----SPSPSPSPSPSPSPSVLASECC 557
Query: 1134 SNSLGMDNLTYSNRPSKDN--TIHTSKNANGS 1163
S +D L + S D+ T H ANG+
Sbjct: 558 SEVERIDTLDSESNSSIDDSATDHQEDVANGN 589
>Hs14777500 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 284
Score = 92.0 bits (227), Expect = 5e-18
Identities = 53/140 (37%), Positives = 73/140 (51%), Gaps = 7/140 (5%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
TL+ L F QP L S +C NC + T+ + ++L + P L IHL RF + S +
Sbjct: 134 TLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTR 193
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEG------ENDVYDLIAVDNHYGGLGGGHYTAYCRNF 1016
KI ++ FP + LD S L K+E Y+L AV H G GHY Y RN
Sbjct: 194 KICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNA 252
Query: 1017 IDGKWYYFDDSRVNEVSPEN 1036
+DGKW+ F+DS + VS E+
Sbjct: 253 VDGKWFCFNDSNICLVSWED 272
>At5g57990 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 829
Score = 91.3 bits (225), Expect = 9e-18
Identities = 69/202 (34%), Positives = 96/202 (47%), Gaps = 19/202 (9%)
Query: 901 SITLDSCLRLFSQPEILGSADSWY-CPNCKQHTQASKQIELWNTPDILLIHLKRFENQRS 959
S+ L F+ E+L + Y C CKQ +A KQ+ + P +L +HLKRFE R
Sbjct: 234 SLRSQRALSRFTAVELLDNGAKVYQCERCKQKVKAKKQLTVSKAPYVLTVHLKRFEAHR- 292
Query: 960 FSDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFID 1018
S+KID V F +DM P++S EG N Y L V HYG GHY + R
Sbjct: 293 -SEKIDRKVDF-TSAIDMKPFVSGPHEG-NLKYTLYGVLVHYGRSSHSGHYACFVRT-SS 348
Query: 1019 GKWYYFDDSRVNEVSPENSIAGSAYLLFYRRRTSGNQTLGNGKLRDIIDISRKEYEQKQD 1078
G WY DD+RV +VS + AY+LFY R N ++ + + +KE
Sbjct: 349 GMWYSLDDNRVVQVSEKTVFNQKAYMLFYVRDRQ------NAVPKNSVPVVKKE------ 396
Query: 1079 EFMTNVETLYAATHTDTESEAS 1100
F TN +L A++ + S
Sbjct: 397 SFATNRASLIVASNIKDQVNGS 418
>Hs8394519 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 372
Score = 90.9 bits (224), Expect = 1e-17
Identities = 58/163 (35%), Positives = 78/163 (47%), Gaps = 17/163 (10%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
TL+ L F QP L S +C NC + T+ + ++L + P L IHL RF + S +
Sbjct: 208 TLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTR 267
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEG------ENDVYDLIAVDNHYGGLGGGHYTAYCRNF 1016
KI ++ FP + LD S L K+E Y+L AV H G GHY Y RN
Sbjct: 268 KICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNA 326
Query: 1017 IDGKWYYFDDSRVNEVS----------PENSIAGSAYLLFYRR 1049
+DGKW F+DS + VS P +AYLL Y +
Sbjct: 327 VDGKWSCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMK 369
>At1g17110 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 891
Score = 89.0 bits (219), Expect = 4e-17
Identities = 78/261 (29%), Positives = 123/261 (46%), Gaps = 18/261 (6%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
+L L F++PE L + + C C + +A K++ + P+IL I LKRF+ R
Sbjct: 566 SLQDALTQFTRPEDLDGENMYRCSRCAGYVRARKELSIHEAPNILTIVLKRFQEGR--YG 623
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLG---GGHYTAYCRNFIDG 1019
KI+ + FP E LDM P+++ + +Y L AV H L GHY +Y ++ + G
Sbjct: 624 KINKCISFP-EMLDMIPFMT-RTGDVPPLYMLYAVIVHLDTLNASFSGHYISYVKD-LRG 680
Query: 1020 KWYYFDDSRVNEVSPENSIAGSAYLLFYRRRTSGNQTLGNGKLRDIIDISRKEYEQKQDE 1079
WY DDS ++ V ++ AY+LFY R Q G + + S+ E K+
Sbjct: 681 NWYRIDDSEIHPVPMTQVMSEGAYMLFYMRSYPRPQR-GEHNGKAPVHHSQPRNEMKEQR 739
Query: 1080 FMTNVETLYAATHTDTESEASDSDRSSVDEEMDSDNSDCENDKKSAFVDQSDI-----SS 1134
N A H +TES +S+ + +E S ++ D S +D +D+ SS
Sbjct: 740 KPVN-RFKPRADHKNTESSSSEWSLFTSSDEA-SFTTESTRDSFST-IDYTDVCHVVDSS 796
Query: 1135 NSLGMDNLTYSN-RPSKDNTI 1154
+ + N Y N PS NT+
Sbjct: 797 SPFAIFNNVYHNVEPSPHNTV 817
>YMR223w [O] KOG1867 Ubiquitin-specific protease
Length = 471
Score = 87.8 bits (216), Expect = 1e-16
Identities = 57/161 (35%), Positives = 86/161 (53%), Gaps = 12/161 (7%)
Query: 899 KSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQR 958
K L CL F + E L + ++C C A KQ+ + P +L++ LKRFE+
Sbjct: 311 KDKKKLYECLDSFHKKEQLKDFN-YHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLL 369
Query: 959 SFSD-KIDATVKFPIEGLDMSPYLSYK---KEGEND-----VYDLIAVDNHYGGLGGGHY 1009
+ S+ K+D ++FP L+M Y S K K EN +Y+LI + +H G + GHY
Sbjct: 370 NGSNRKLDDFIEFPTY-LNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGHY 428
Query: 1010 TAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRR 1050
A+C+ G+W+ F+DS V+ +S E + AYLLFY R
Sbjct: 429 IAFCK-ISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIR 468
Score = 72.0 bits (175), Expect = 6e-12
Identities = 51/199 (25%), Positives = 87/199 (43%), Gaps = 30/199 (15%)
Query: 337 GIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLL 396
G+ GL N+G+TC+M+S LQCL+H P + + + + + +P H L
Sbjct: 135 GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHEL 194
Query: 397 YSLFAPSYGQSTFYAPRNFKNTI------GHYNSLFAGYGQQDSQEFLAFLLDGLHEDLN 450
Y S+ + I N AGY QQD+ EF F+++ +H+
Sbjct: 195 YGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQS-- 252
Query: 451 RVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPN 510
YV + PN ++ + K+ + ++ +F G +S++VCP
Sbjct: 253 ------YV--LDLPNAKEVSRAN-------------NKQCECIVHTVFEGSLESSIVCPG 291
Query: 511 C-NHVSITFDPYNDLTLPL 528
C N+ T DP+ DL+L +
Sbjct: 292 CQNNSKTTIDPFLDLSLDI 310
>At4g17890_2 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 544
Score = 87.8 bits (216), Expect = 1e-16
Identities = 52/149 (34%), Positives = 82/149 (54%), Gaps = 6/149 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
TL S L F++ E L + C NC + KQ+ L P + HLKRF+N + +
Sbjct: 180 TLGSALESFTRVEKLD--EQLTCDNCNEKVSKEKQLLLDKLPLVATFHLKRFKNNGLYME 237
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGE-NDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGK 1020
KI VK P+E +D+ PY+ +E E + Y L A+ H+G + GHY++Y R+
Sbjct: 238 KIYKHVKIPLE-IDLQPYMRNIQENEVSTKYHLYALVEHFGYSVAYGHYSSYVRS-APKI 295
Query: 1021 WYYFDDSRVNEVSPENSIAGSAYLLFYRR 1049
W++FDDS+V + + ++ +Y+LFY R
Sbjct: 296 WHHFDDSKVTRIDEDMVLSQDSYILFYAR 324
>SPCC1682.12c [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 457
Score = 87.0 bits (214), Expect = 2e-16
Identities = 56/157 (35%), Positives = 84/157 (52%), Gaps = 6/157 (3%)
Query: 899 KSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQR 958
K S DS L+ F E L + + C NCKQ ASKQ+ ++ P+IL IH KRF
Sbjct: 282 KGSSLADS-LKHFVHAEKLTKQNKYRCENCKQLVDASKQMTIYRAPNILTIHFKRFTFNG 340
Query: 959 SFSDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGG-LGGGHYTAYCRNFI 1017
S KI + +P E ++ PY+S + Y+LI V H GG GHY ++C++
Sbjct: 341 FQSSKISKQISYP-ESFNLGPYMS--DPNCSCWYELIGVLVHAGGSTRSGHYYSFCKS-S 396
Query: 1018 DGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRRTSGN 1054
+G W FDD V+ S + + AY+L Y+R+++ +
Sbjct: 397 NGVWLKFDDDFVSNSSIDRVLNQQAYILQYKRKSTSS 433
>At5g46740 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 732
Score = 85.1 bits (209), Expect = 6e-16
Identities = 78/316 (24%), Positives = 140/316 (43%), Gaps = 17/316 (5%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
TL L F+ E L D C NCK+ KQ+ P + HLKRF N +
Sbjct: 324 TLWKALESFTCVEKL--EDQLTCDNCKEKVTKEKQLRFDKLPPVATFHLKRFTNDGVTME 381
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGE-NDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGK 1020
KI ++FP+E LD+SP++S + E + Y L A H G GHY++Y R+ +
Sbjct: 382 KIFDHIEFPLE-LDLSPFMSSNHDPEVSTRYHLYAFVEHIGIRATFGHYSSYVRSAPE-T 439
Query: 1021 WYYFDDSRVNEVSPENSIAGSAYLLFYRRRTSGNQTLGNGKLRDIIDISRKEYEQKQDEF 1080
W+ FDDS+V +S E ++ AY+LFY R + + +L+ + + + +
Sbjct: 440 WHNFDDSKVTRISEERVLSRPAYILFYAREGTPWFSSTFEQLKTVFEATPLHFSP----- 494
Query: 1081 MTNVETLYAATHTDTESEASDSDRSSVDEEMDSDNSDCENDKKSAF--VDQSDISSNSLG 1138
++ ++ Y + D S+A + ++ +S C+ K+ F + S+ +S
Sbjct: 495 VSVLDNSYES--VDNSSKACNDSVGVSIPDVKWPDSCCQEPKEEVFHSAESSNNEDSSAM 552
Query: 1139 MDNLTYSNRPSKDNTIHTSKNANGSIESTLNNNELPEAEQTVTATERKGALQYNVSSLEV 1198
+D L + S+ TS+ T N + ++E+ T + + +
Sbjct: 553 IDAL--GSPQSEKPFAETSQQTEPESCPTENKAYIDKSEKPFAETSQPKEPKPFADRASI 610
Query: 1199 GSNIAKLDTHDSSRRK 1214
+ + K+ D S ++
Sbjct: 611 DAPLLKVQNQDISPKR 626
Score = 60.1 bits (144), Expect = 2e-08
Identities = 67/263 (25%), Positives = 105/263 (39%), Gaps = 45/263 (17%)
Query: 335 PSGI-MGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF- 392
P+G+ GL N GNTC++ S LQC H L + Y N N K V A
Sbjct: 158 PTGVGAGLYNSGNTCFIASVLQCFTHTVPLIDSLRSFMYGNPCNCGN---EKFCVMQALR 214
Query: 393 GHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRV 452
H+ +L + YG + F++ + +++S F Q+D+ EFL LD L
Sbjct: 215 DHIELALRSSGYGINI----DRFRDNLTYFSSDFMINHQEDAHEFLQSFLDKL------- 263
Query: 453 IEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCN 512
++ L N + ++ +++ ++F G STL C NCN
Sbjct: 264 --------------------ERCCLDPKNQLGSVSSQDLNIVDNVFGGGLMSTLCCCNCN 303
Query: 513 HVSITFDP-------YNDL-TLPLPIENYWSTKVTIFPQNSPPCTLEVELSKTSSYNDLK 564
VS TF+P D+ TL +E++ + C +V K ++ L
Sbjct: 304 SVSNTFEPSLGWSLEIEDVNTLWKALESFTCVEKLEDQLTCDNCKEKVTKEKQLRFDKLP 363
Query: 565 AYVAQHANMHANDLIGAE-IFNH 586
H ND + E IF+H
Sbjct: 364 PVATFHLKRFTNDGVTMEKIFDH 386
>Hs14149817 [O] KOG1867 Ubiquitin-specific protease
Length = 712
Score = 82.8 bits (203), Expect = 3e-15
Identities = 53/137 (38%), Positives = 77/137 (55%), Gaps = 10/137 (7%)
Query: 932 TQASKQIELWNTPDILLIHLKRFE-NQRSFSDKIDATVKFPIEGLDMSPYLSYKK----E 986
T+A KQ+ + + P +L +HLKRF + R+ +KI V F E L+M PY +
Sbjct: 555 TEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFE-EILNMEPYCCRETLKSLR 613
Query: 987 GENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLL 1045
E +YDL AV H+G G G GHYTAYC N G W + +DS+++ + + AY+L
Sbjct: 614 PECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYIL 673
Query: 1046 FYRRRTSGNQTLGNGKL 1062
FY +R + N G+ KL
Sbjct: 674 FYTQRVTEN---GHSKL 687
Score = 63.9 bits (154), Expect = 1e-09
Identities = 73/294 (24%), Positives = 113/294 (37%), Gaps = 81/294 (27%)
Query: 337 GIMGLSNLGNTCYMNSALQCLLHIP---------ELNEYFLYKGYEREININNP------ 381
G+ GL NLGNTCYMNS LQ L H+ +LN++ E+ + +P
Sbjct: 271 GVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTV 330
Query: 382 -------------------------------LGHKGDVAH---------AFGHLLYSLFA 401
G K ++ + H L++LF
Sbjct: 331 VYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQ 390
Query: 402 PSY-GQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYVNK 460
+ G+ +P +++ F GY QQD+QEFL LLD + +L
Sbjct: 391 VMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQREL----------- 439
Query: 461 PEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDP 520
+ T L+ + IK+ +V+ ++F G S + C C++ S T +P
Sbjct: 440 -------ETTGTSLPALIPTSQRKLIKQVL-NVVNNIFHGQLLSQVTCLACDNKSNTIEP 491
Query: 521 YNDLTLPLPIENYWSTKVTIFPQNSPPCTLEVELSKTSSYNDL--KAYVAQHAN 572
+ DL+L P E Y + I Q PC + L+K + L K YV N
Sbjct: 492 FWDLSLEFP-ERYQCSGKDIASQ---PCLVTEMLAKFTETEALEGKIYVCDQCN 541
>At2g32780 [O] KOG1873 Ubiquitin-specific protease
Length = 1083
Score = 82.4 bits (202), Expect = 4e-15
Identities = 91/352 (25%), Positives = 151/352 (42%), Gaps = 57/352 (16%)
Query: 300 KDYDSQIISLVVEVKQKSSNQHWPSNFFH----YNKLNAPSG--IMGLSNLGNTCYMNSA 353
KD +++ L+ E + + + + F Y + A G + GL NLGNTC+ NS
Sbjct: 157 KDLLLEVVKLIRERSPNTYSASFETEFSCSGSIYGGIEARDGYAVRGLVNLGNTCFFNSV 216
Query: 354 LQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLLYSLFAPSYGQSTFYA-- 411
+Q LL + +L E+FL + +++++ PL L LFA S +++ +
Sbjct: 217 MQNLLSLDQLREHFL----KEDLSVSGPLVSS----------LKELFAESNSEASVFRNE 262
Query: 412 --PRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYVNKPEFPNDGQI 469
PR+ ++ F GY Q DS E L LLDGL IE+ + K +D
Sbjct: 263 INPRDLFFSVCSQAPQFRGYQQHDSHELLRCLLDGLS------IEESSLRKKLGVSDSND 316
Query: 470 DDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLP 529
T Q ++I +F G ST+ C C H S ++P+ DL+LP+P
Sbjct: 317 SSTYQ---------------KPTLIDSVFGGEISSTVSCLECGHFSKVYEPFMDLSLPVP 361
Query: 530 IENYWSTKVTIFPQNSPPCTLEVELSKTSSYNDLKAYVAQHANMHANDLIGAEIFNHQFY 589
K I Q + L + D + A+ A+ H N + +H+
Sbjct: 362 SMKLPPKKQQILSQ------AKEVLKNGAVSKDSEVVSAKPASDH-NSTVPLFPSDHKIQ 414
Query: 590 NNYE-SNVEADYLPISELISESDTVIFYEVHRGQDDLVVPILNTRFEEGFKT 640
+ E S+ E D + +S++ SDT E +G + ++V T + +T
Sbjct: 415 SRPETSDNETDLVLLSDV---SDTAPSTEA-KGVNQILVGSTETLMHDNDRT 462
Score = 64.7 bits (156), Expect = 9e-10
Identities = 42/130 (32%), Positives = 62/130 (47%), Gaps = 15/130 (11%)
Query: 934 ASKQIELWNTPDILLIHLKRF-ENQRSFSDKIDATVKFPIEGLDMSPYLSYK-KEGENDV 991
A K++ + P +L IHLKRF ++ R K+ V F E +D+S Y+ + E + V
Sbjct: 954 ARKKVLINKAPPVLTIHLKRFSQDARGRVSKLSGHVDFQ-EFIDLSKYMDTRCSEEDEPV 1012
Query: 992 YDLIAVDNHYGGLGGGHYTAYCRNFIDGK------------WYYFDDSRVNEVSPENSIA 1039
Y L + H G + GHY +Y R + WY+ DS+V S E +
Sbjct: 1013 YRLAGLVEHLGAMSRGHYVSYIRGGHKERRDSDTKEPNSSIWYHASDSQVRPASLEEVLR 1072
Query: 1040 GSAYLLFYRR 1049
AY+LFY R
Sbjct: 1073 SEAYILFYER 1082
>Hs20540195 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 823
Score = 80.1 bits (196), Expect = 2e-14
Identities = 55/152 (36%), Positives = 82/152 (53%), Gaps = 6/152 (3%)
Query: 899 KSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQR 958
K++ +++ L F +PE L +S+ C CK+ ASK+ + + ++L + LKRF N
Sbjct: 265 KAAQSVNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFAN-- 322
Query: 959 SFSDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFI 1017
KI VK+P E LD+ PY+S + GE VY L AV H G GHY Y +
Sbjct: 323 FTGGKIAKDVKYP-EYLDIRPYMS-QPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIK-AS 379
Query: 1018 DGKWYYFDDSRVNEVSPENSIAGSAYLLFYRR 1049
+G WY +DS V+ + ++ AY+LFY R
Sbjct: 380 NGLWYQMNDSIVSTSDIRSVLSQQAYVLFYIR 411
Score = 62.8 bits (151), Expect = 3e-09
Identities = 53/198 (26%), Positives = 77/198 (38%), Gaps = 54/198 (27%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFG------ 393
GL NLGNTC+ N+ALQCL + P L Y L + + HA G
Sbjct: 112 GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSK-------------TCHAEGFCMMCT 158
Query: 394 ---HLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLN 450
H+ +L P + + H F Q+D+ EFL + +D +
Sbjct: 159 MQAHITQALSNPGDVIKPMFVINEMRRIARH----FRFGNQEDAHEFLQYTVDAM----- 209
Query: 451 RVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPN 510
+K +N ++D Q L + +F G +S + C N
Sbjct: 210 ---QKACLN-----GSNKLDRHTQATTL---------------VCQIFGGYLRSRVKCLN 246
Query: 511 CNHVSITFDPYNDLTLPL 528
C VS TFDPY D+TL +
Sbjct: 247 CKGVSDTFDPYLDITLEI 264
>Hs18557591 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 80.1 bits (196), Expect = 2e-14
Identities = 52/150 (34%), Positives = 83/150 (54%), Gaps = 6/150 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
++ L +PE L ++++C C Q ASK + L N+ +L++ LKRF + +
Sbjct: 232 SVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHNSAKVLILVLKRFPDVT--GN 289
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKW 1021
KI V++P E LDM PY+S + G VY L AV H G GHY++Y + +G+W
Sbjct: 290 KIAKNVQYP-ECLDMQPYMSQQNTGPL-VYVLYAVLVHAGWSCHNGHYSSYVK-AQEGQW 346
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
Y DD+ V S + ++ AY+LFY +++
Sbjct: 347 YKMDDAEVTASSITSVLSQQAYVLFYIQKS 376
Score = 70.1 bits (170), Expect = 2e-11
Identities = 52/193 (26%), Positives = 86/193 (43%), Gaps = 50/193 (25%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF-GHLLYS 398
GL N+GNTCY+N++LQCL + P L Y L++ + + + HKG + H+ +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYKPPLANYMLFREHSQTCH-----RHKGCMLCTMQAHITRA 135
Query: 399 LFAPSYGQSTFYAPRNFKNTIGHYNSLFAGY---GQQDSQEFLAFLLDGLHEDLNRVIEK 455
L P + I +L AG+ Q+D+ EFL F +D +
Sbjct: 136 LHIPGH-------------VIQPSQALAAGFHRGKQEDAHEFLMFTVDAM---------- 172
Query: 456 PYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVS 515
K P Q+D ++ ++I +F G ++S + C +C+ +S
Sbjct: 173 ---RKACLPGHKQVDR---------------HSKDTTLIHQIFGGYWRSQIKCLHCHGIS 214
Query: 516 ITFDPYNDLTLPL 528
TFDPY D+ L +
Sbjct: 215 DTFDPYLDIALDI 227
>Hs22044534 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 77.8 bits (190), Expect = 1e-13
Identities = 51/150 (34%), Positives = 81/150 (54%), Gaps = 6/150 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
++ L +PE L ++++C C Q ASK + L + +L++ LKRF + +
Sbjct: 232 SVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVT--GN 289
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKW 1021
KI V++P E LDM PY+S + G VY L AV H G GHY +Y + +G+W
Sbjct: 290 KIAKNVQYP-ECLDMQPYMSQQNTGPL-VYVLYAVLVHAGWSCHNGHYFSYVK-AQEGQW 346
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
Y DD+ V S + ++ AY+LFY +++
Sbjct: 347 YKMDDAEVTAASITSVLSQQAYVLFYIQKS 376
Score = 65.9 bits (159), Expect = 4e-10
Identities = 51/193 (26%), Positives = 84/193 (43%), Gaps = 50/193 (25%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF-GHLLYS 398
GL N+GNTCY+N++LQCL + L Y L + + + + HKG + H+ +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTTPLANYMLSREHSQTCH-----RHKGCMLCTMQAHITRA 135
Query: 399 LFAPSYGQSTFYAPRNFKNTIGHYNSLFAGY---GQQDSQEFLAFLLDGLHEDLNRVIEK 455
L P + I +L AG+ Q+D+ EFL F +D +
Sbjct: 136 LHNPGH-------------VIQPSQALAAGFHRGKQEDAHEFLMFTVDAM---------- 172
Query: 456 PYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVS 515
K P Q+D ++ ++I +F G ++S + C +C+ +S
Sbjct: 173 ---KKACLPRHKQVDH---------------HSKDTTLIHQIFGGYWRSQIKCLHCHGIS 214
Query: 516 ITFDPYNDLTLPL 528
TFDPY D+ L +
Sbjct: 215 DTFDPYLDIALDI 227
>Hs22044530 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 565
Score = 77.4 bits (189), Expect = 1e-13
Identities = 51/150 (34%), Positives = 81/150 (54%), Gaps = 6/150 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
++ L +PE L ++++C C Q ASK + L + +L++ LKRF + +
Sbjct: 267 SVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVT--GN 324
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKW 1021
KI V++P E LDM PY+S + G VY L AV H G GHY +Y + +G+W
Sbjct: 325 KIAKNVQYP-ECLDMQPYMSQQNTGPL-VYVLYAVLVHAGWSCYNGHYFSYVK-AQEGQW 381
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
Y DD+ V S + ++ AY+LFY +++
Sbjct: 382 YKMDDAEVTAASITSVLSQQAYVLFYIQKS 411
Score = 68.9 bits (167), Expect = 5e-11
Identities = 52/193 (26%), Positives = 85/193 (43%), Gaps = 50/193 (25%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF-GHLLYS 398
GL N+GNTCY+N++LQCL + P L Y L + + + + HKG + H+ +
Sbjct: 116 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH-----RHKGCMLCTMQAHITRA 170
Query: 399 LFAPSYGQSTFYAPRNFKNTIGHYNSLFAGY---GQQDSQEFLAFLLDGLHEDLNRVIEK 455
L P + I +L AG+ Q+D+ EFL F +D +
Sbjct: 171 LHNPGH-------------VIQPSQALAAGFHRGKQEDAHEFLMFTVDAM---------- 207
Query: 456 PYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVS 515
K P Q+D ++ ++I +F G ++S + C +C+ +S
Sbjct: 208 ---KKACLPGHKQVDH---------------HSKDTTLIHQIFGGYWRSQIKCLHCHGIS 249
Query: 516 ITFDPYNDLTLPL 528
TFDPY D+ L +
Sbjct: 250 DTFDPYLDIALDI 262
>Hs22044539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 1074
Score = 77.0 bits (188), Expect = 2e-13
Identities = 51/149 (34%), Positives = 80/149 (53%), Gaps = 6/149 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
++ L +PE L ++++C C Q ASK + L + +L++ LKRF + +
Sbjct: 232 SVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVT--GN 289
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWY 1022
KI V++P E LDM PY+S + G VY L AV H G GHY +Y + +G+WY
Sbjct: 290 KIAKNVQYP-ECLDMQPYMSQQNTGPL-VYVLYAVLVH-AGCYNGHYFSYVK-AQEGQWY 345
Query: 1023 YFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
DD+ V S + + AY+LFY +++
Sbjct: 346 KMDDAEVTASSITSVLTQQAYVLFYIQKS 374
Score = 76.6 bits (187), Expect = 2e-13
Identities = 51/150 (34%), Positives = 80/150 (53%), Gaps = 6/150 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
++ L +PE L ++++C C Q ASK + L + +L++ LKRF + +
Sbjct: 776 SVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVT--GN 833
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKW 1021
KI V++P E LDM PY+S + G VY L AV H G GHY +Y + +G+W
Sbjct: 834 KIAKNVQYP-ECLDMQPYMSQQNTGPL-VYVLYAVLVHAGWSCHNGHYFSYVK-AQEGQW 890
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
Y DD+ V S + + AY+LFY +++
Sbjct: 891 YKMDDAEVTASSITSVLTQQAYVLFYIQKS 920
Score = 68.2 bits (165), Expect = 8e-11
Identities = 52/193 (26%), Positives = 84/193 (42%), Gaps = 50/193 (25%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF-GHLLYS 398
GL N+GNTCY+N++LQCL + P L Y L + + + HKG + H+ +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTC-----YRHKGCMLCTMQAHITRA 135
Query: 399 LFAPSYGQSTFYAPRNFKNTIGHYNSLFAGY---GQQDSQEFLAFLLDGLHEDLNRVIEK 455
L P + I +L AG+ Q+D+ EFL F +D +
Sbjct: 136 LHNPGH-------------VIQPSQALAAGFHRGKQEDAHEFLMFTVDAM---------- 172
Query: 456 PYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVS 515
K P Q+D ++ ++I +F G ++S + C +C+ +S
Sbjct: 173 ---KKACLPGHKQVDH---------------HSKDTTLIHQIFGGYWRSQIKCLHCHGIS 214
Query: 516 ITFDPYNDLTLPL 528
TFDPY D+ L +
Sbjct: 215 DTFDPYLDIALDI 227
Score = 65.5 bits (158), Expect = 5e-10
Identities = 52/192 (27%), Positives = 83/192 (43%), Gaps = 53/192 (27%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLLYSL 399
GL N+GNTCY+N++LQCL + P L Y L RE + N + + H+ +L
Sbjct: 630 GLQNMGNTCYVNASLQCLTYTPPLANYML----SREHSQNGCM-----LCTMQAHITRAL 680
Query: 400 FAPSYGQSTFYAPRNFKNTIGHYNSLFAGY---GQQDSQEFLAFLLDGLHEDLNRVIEKP 456
P + I +L AG+ Q+D+ EFL F +D +
Sbjct: 681 HNPGH-------------VIQPSQALAAGFHRGKQEDAHEFLMFTVDAM----------- 716
Query: 457 YVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSI 516
K P Q+D ++ ++I +F G ++S + C +C+ +S
Sbjct: 717 --KKACLPGHKQVDH---------------HSKDTTLIHQIFGGYWRSQIKCLHCHGISD 759
Query: 517 TFDPYNDLTLPL 528
TFDPY D+ L +
Sbjct: 760 TFDPYLDIALDI 771
>Hs22044565 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 398
Score = 76.6 bits (187), Expect = 2e-13
Identities = 51/150 (34%), Positives = 80/150 (53%), Gaps = 6/150 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
++ L +PE L ++++C C Q ASK + L + +L++ LKRF + +
Sbjct: 232 SVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLALHTSAKVLILVLKRFSDVT--GN 289
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKW 1021
KI V++P E LDM PY+S + G VY L AV H G GHY +Y + +G+W
Sbjct: 290 KIAKNVQYP-ECLDMQPYMSQQNTGPL-VYVLYAVLVHAGWSCHNGHYFSYVK-AQEGQW 346
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
Y DD+ V S + + AY+LFY +++
Sbjct: 347 YKIDDAEVTASSITSVLTQQAYVLFYIQKS 376
Score = 70.5 bits (171), Expect = 2e-11
Identities = 53/193 (27%), Positives = 86/193 (44%), Gaps = 50/193 (25%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF-GHLLYS 398
GL N+GNTCY+N++LQCL + P L Y L + + + + HKG + A H+ +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH-----RHKGCMLCAMQAHITRA 135
Query: 399 LFAPSYGQSTFYAPRNFKNTIGHYNSLFAGY---GQQDSQEFLAFLLDGLHEDLNRVIEK 455
L P + I +L AG+ Q+D+ EFL F +D +
Sbjct: 136 LHNPGH-------------VIQPSQALAAGFHRGKQEDAHEFLMFTVDAM---------- 172
Query: 456 PYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVS 515
K P Q+D ++ ++I +F G ++S + C +C+ +S
Sbjct: 173 ---KKACLPGHKQVDH---------------HSKDTTLIHQIFGGYWRSQIKCLHCHGIS 214
Query: 516 ITFDPYNDLTLPL 528
TFDPY D+ L +
Sbjct: 215 DTFDPYLDIALDI 227
>Hs22044559 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 76.6 bits (187), Expect = 2e-13
Identities = 51/150 (34%), Positives = 80/150 (53%), Gaps = 6/150 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
++ L +PE L ++++C C Q ASK + L + +L++ LKRF + +
Sbjct: 232 SVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVT--GN 289
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKW 1021
KI V++P E LDM PY+S + G VY L AV H G GHY +Y + +G+W
Sbjct: 290 KIAKNVQYP-ECLDMQPYMSQQNTGPL-VYVLYAVLVHAGWSCHNGHYFSYVK-AQEGQW 346
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
Y DD+ V S + + AY+LFY +++
Sbjct: 347 YKMDDAEVTASSITSVLTQQAYVLFYIQKS 376
Score = 68.9 bits (167), Expect = 5e-11
Identities = 52/193 (26%), Positives = 85/193 (43%), Gaps = 50/193 (25%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF-GHLLYS 398
GL N+GNTCY+N++LQCL + P L Y L + + + + HKG + H+ +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH-----RHKGCMLCTMQAHITRA 135
Query: 399 LFAPSYGQSTFYAPRNFKNTIGHYNSLFAGY---GQQDSQEFLAFLLDGLHEDLNRVIEK 455
L P + I +L AG+ Q+D+ EFL F +D +
Sbjct: 136 LHNPGH-------------VIQPSQALAAGFHRGKQEDAHEFLMFTVDAM---------- 172
Query: 456 PYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVS 515
K P Q+D ++ ++I +F G ++S + C +C+ +S
Sbjct: 173 ---KKACLPGHKQVDH---------------HSKDTTLIHQIFGGYWRSQIKCLHCHGIS 214
Query: 516 ITFDPYNDLTLPL 528
TFDPY D+ L +
Sbjct: 215 DTFDPYLDIALDI 227
>Hs22044555 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 489
Score = 76.6 bits (187), Expect = 2e-13
Identities = 51/150 (34%), Positives = 80/150 (53%), Gaps = 6/150 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
++ L +PE L ++++C C Q ASK + L + +L++ LKRF + +
Sbjct: 191 SVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVT--GN 248
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKW 1021
KI V++P E LDM PY+S + G VY L AV H G GHY +Y + +G+W
Sbjct: 249 KIAKNVQYP-ECLDMQPYMSQQNTGPL-VYVLYAVLVHAGWSCHNGHYFSYVK-AQEGQW 305
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
Y DD+ V S + + AY+LFY +++
Sbjct: 306 YKMDDAEVTASSITSVLTQQAYVLFYIQKS 335
>Hs22044551 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 76.6 bits (187), Expect = 2e-13
Identities = 51/150 (34%), Positives = 80/150 (53%), Gaps = 6/150 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
++ L +PE L ++++C C Q ASK + L + +L++ LKRF + +
Sbjct: 232 SVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVT--GN 289
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKW 1021
KI V++P E LDM PY+S + G VY L AV H G GHY +Y + +G+W
Sbjct: 290 KIAKNVQYP-ECLDMQPYMSQQNTGPL-VYVLYAVLVHAGWSCHNGHYFSYVK-AQEGQW 346
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
Y DD+ V S + + AY+LFY +++
Sbjct: 347 YKMDDAEVTASSITSVLTQQAYVLFYIQKS 376
Score = 68.9 bits (167), Expect = 5e-11
Identities = 52/193 (26%), Positives = 85/193 (43%), Gaps = 50/193 (25%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF-GHLLYS 398
GL N+GNTCY+N++LQCL + P L Y L + + + + HKG + H+ +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH-----RHKGCMLCTMQAHITRA 135
Query: 399 LFAPSYGQSTFYAPRNFKNTIGHYNSLFAGY---GQQDSQEFLAFLLDGLHEDLNRVIEK 455
L P + I +L AG+ Q+D+ EFL F +D +
Sbjct: 136 LHNPGH-------------VIQPSQALAAGFHRGKQEDAHEFLMFTVDAM---------- 172
Query: 456 PYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVS 515
K P Q+D ++ ++I +F G ++S + C +C+ +S
Sbjct: 173 ---KKACLPGHKQVDH---------------HSKDTTLIHQIFGGYWRSQIKCLHCHGIS 214
Query: 516 ITFDPYNDLTLPL 528
TFDPY D+ L +
Sbjct: 215 DTFDPYLDIALDI 227
>Hs22044543 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 76.6 bits (187), Expect = 2e-13
Identities = 51/150 (34%), Positives = 80/150 (53%), Gaps = 6/150 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
++ L +PE L ++++C C Q ASK + L + +L++ LKRF + +
Sbjct: 232 SVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVT--GN 289
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKW 1021
KI V++P E LDM PY+S + G VY L AV H G GHY +Y + +G+W
Sbjct: 290 KIAKNVQYP-ECLDMQPYMSQQNTGPL-VYVLYAVLVHAGWSCHNGHYFSYVK-AQEGQW 346
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
Y DD+ V S + + AY+LFY +++
Sbjct: 347 YKMDDAEVTASSITSVLTQQAYVLFYIQKS 376
Score = 69.7 bits (169), Expect = 3e-11
Identities = 52/193 (26%), Positives = 85/193 (43%), Gaps = 50/193 (25%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF-GHLLYS 398
GL N+GNTCY+N++LQCL + P L Y L + + + + HKG + H+ +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH-----RHKGCMLCTMQAHITRA 135
Query: 399 LFAPSYGQSTFYAPRNFKNTIGHYNSLFAGY---GQQDSQEFLAFLLDGLHEDLNRVIEK 455
L P + I +L AG+ Q+D+ EFL F +D +
Sbjct: 136 LHNPGH-------------VIQPSQALAAGFHRGKQEDAHEFLMFTVDAM---------- 172
Query: 456 PYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVS 515
K P Q+D ++ ++I +F G ++S + C +C+ +S
Sbjct: 173 ---KKACLPGHKQVDH---------------HSKDTTLIHQIFGGYWRSQIKCLHCHRIS 214
Query: 516 ITFDPYNDLTLPL 528
TFDPY D+ L +
Sbjct: 215 DTFDPYLDIALDI 227
>Hs22044541 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 525
Score = 76.6 bits (187), Expect = 2e-13
Identities = 51/150 (34%), Positives = 80/150 (53%), Gaps = 6/150 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
++ L +PE L ++++C C Q ASK + L + +L++ LKRF + +
Sbjct: 227 SVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVT--GN 284
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKW 1021
KI V++P E LDM PY+S + G VY L AV H G GHY +Y + +G+W
Sbjct: 285 KIAKNVQYP-ECLDMQPYMSQQNTGPL-VYVLYAVLVHAGWSCHNGHYFSYVK-AQEGQW 341
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
Y DD+ V S + + AY+LFY +++
Sbjct: 342 YKMDDAEVTASSITSVLTQQAYVLFYIQKS 371
Score = 65.1 bits (157), Expect = 7e-10
Identities = 52/192 (27%), Positives = 83/192 (43%), Gaps = 53/192 (27%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLLYSL 399
GL N+GNTCY+N++LQCL + P L Y L RE + N + + H+ +L
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYML----SREHSQNGCM-----LCTMQAHITRAL 131
Query: 400 FAPSYGQSTFYAPRNFKNTIGHYNSLFAGY---GQQDSQEFLAFLLDGLHEDLNRVIEKP 456
P + I +L AG+ Q+D+ EFL F +D +
Sbjct: 132 HNPGH-------------VIQPSQALAAGFHRGKQEDAHEFLMFTVDAM----------- 167
Query: 457 YVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSI 516
K P Q+D ++ ++I +F G ++S + C +C+ +S
Sbjct: 168 --KKACLPGHKQVDH---------------HAKDTTLIHQIFGGYWRSQIKCLHCHGISD 210
Query: 517 TFDPYNDLTLPL 528
TFDPY D+ L +
Sbjct: 211 TFDPYLDIALDI 222
>Hs22044537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 76.6 bits (187), Expect = 2e-13
Identities = 51/150 (34%), Positives = 80/150 (53%), Gaps = 6/150 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
++ L +PE L ++++C C Q ASK + L + +L++ LKRF + +
Sbjct: 232 SVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVT--GN 289
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKW 1021
KI V++P E LDM PY+S + G VY L AV H G GHY +Y + +G+W
Sbjct: 290 KIAKNVQYP-ECLDMQPYMSQQNTGPL-VYVLYAVLVHAGWSCHNGHYFSYVK-AQEGQW 346
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
Y DD+ V S + + AY+LFY +++
Sbjct: 347 YKMDDAEVTASSITSVLTQQAYVLFYIQKS 376
Score = 70.1 bits (170), Expect = 2e-11
Identities = 52/193 (26%), Positives = 86/193 (43%), Gaps = 50/193 (25%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF-GHLLYS 398
GL N+GNTCY+N++LQCL + P L Y L++ + + + HKG + H+ +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYKPPLANYMLFREHSQTCH-----RHKGCMLCTMQAHITRA 135
Query: 399 LFAPSYGQSTFYAPRNFKNTIGHYNSLFAGY---GQQDSQEFLAFLLDGLHEDLNRVIEK 455
L P + I +L AG+ Q+D+ EFL F +D +
Sbjct: 136 LHIPGH-------------VIQPSQALAAGFHRGKQEDAHEFLMFTVDAM---------- 172
Query: 456 PYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVS 515
K P Q+D ++ ++I +F G ++S + C +C+ +S
Sbjct: 173 ---RKACLPGHKQVDR---------------HSKDTTLIHQIFGGYWRSQIKCLHCHGIS 214
Query: 516 ITFDPYNDLTLPL 528
TFDPY D+ L +
Sbjct: 215 DTFDPYLDIALDI 227
>Hs22044547 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 76.3 bits (186), Expect = 3e-13
Identities = 51/150 (34%), Positives = 80/150 (53%), Gaps = 6/150 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
++ L +PE L ++++C C Q ASK + L + +L++ LKRF + +
Sbjct: 232 SVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVT--GN 289
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKW 1021
KI V++P E LDM PY+S + G VY L AV H G GHY +Y + +G+W
Sbjct: 290 KIAKNVQYP-ECLDMQPYMSQQNTGPL-VYVLYAVLVHAGWSCYNGHYFSYVK-AQEGQW 346
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
Y DD+ V S + + AY+LFY +++
Sbjct: 347 YKMDDAEVTASSITSVLTQQAYVLFYIQKS 376
Score = 69.3 bits (168), Expect = 4e-11
Identities = 52/193 (26%), Positives = 85/193 (43%), Gaps = 50/193 (25%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF-GHLLYS 398
GL N+GNTCY+N++LQCL + P L Y L + + + + HKG + H+ +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPSLANYMLSREHSQTCH-----RHKGCMLCTMQAHITRA 135
Query: 399 LFAPSYGQSTFYAPRNFKNTIGHYNSLFAGY---GQQDSQEFLAFLLDGLHEDLNRVIEK 455
L P + I +L AG+ Q+D+ EFL F +D +
Sbjct: 136 LHNPGH-------------VIQPSQALAAGFHRGKQEDAHEFLMFTVDAM---------- 172
Query: 456 PYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVS 515
K P Q+D ++ ++I +F G ++S + C +C+ +S
Sbjct: 173 ---KKACLPGHKQVDH---------------HSKDTTLIHQIFGGYWRSQIKCLHCHGIS 214
Query: 516 ITFDPYNDLTLPL 528
TFDPY D+ L +
Sbjct: 215 DTFDPYLDIALDI 227
>7300926 [O] KOG1864 Ubiquitin-specific protease
Length = 424
Score = 75.5 bits (184), Expect = 5e-13
Identities = 75/282 (26%), Positives = 122/282 (42%), Gaps = 46/282 (16%)
Query: 808 TVSDTANDLATKSYTSPNPEENVTSSAEA------LDGTLHLKVSPLLDVHNAIICEWEA 861
+ S A+ +A+KS ++ N N S+ + G+L+ S +LD ++
Sbjct: 147 STSAMASSIASKSSSTSNSNSNSNSTTNSNGNSSNSTGSLNANTS-VLDASGSLTATTTP 205
Query: 862 VKVINVFDEDNGVN----WDHPAILENLSLSEVRKTRAQTEKS--------------SIT 903
+ + NG N W H I + + SE R +T S + +
Sbjct: 206 I-ISGNGTGTNGANSEPTWVHE-IFQGILTSETRCLNCETVSSKDENFFDLQVDVDQNTS 263
Query: 904 LDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD- 962
+ CLR FS E L S + + C NC + +A K++ + P IL +HLKRF+ F+
Sbjct: 264 ITHCLRCFSNTETLCSDNKFKCDNCCSYQEAQKRMRVKKLPMILALHLKRFKYMEQFNRH 323
Query: 963 -KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGK 1020
K+ V FP+E + S + +YDL AV H G G GHY + ++ G
Sbjct: 324 IKVSHRVVFPLELRLFN--TSDDAVNPDRLYDLTAVVIHCGSGPNRGHYISIVKS--HGL 379
Query: 1021 WYYFDDSRVNEV------------SPENSIAGSAYLLFYRRR 1050
W FDD V+++ S + + + Y+LFY+ R
Sbjct: 380 WLLFDDDMVDKIEASTIEDFYGLTSDIHKSSETGYILFYQSR 421
>Hs5454156 [O] KOG1873 Ubiquitin-specific protease
Length = 823
Score = 75.1 bits (183), Expect = 7e-13
Identities = 72/261 (27%), Positives = 120/261 (45%), Gaps = 35/261 (13%)
Query: 332 LNAPSGIM--GLSNLGNTCYMNSALQCLLHIPELNEYF--------LYKGYEREININNP 381
+N+P I GLSNLGNTC+ N+ +Q L P L E + K ++ + P
Sbjct: 187 MNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEP 246
Query: 382 ----LGHKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEF 437
L G + A L + G T P+ + + F GY QQDSQE
Sbjct: 247 LEINLEPPGPLTLAMSQFLNEMQETKKGVVT---PKELFSQVCKKAVRFKGYQQQDSQEL 303
Query: 438 LAFLLDGL----HEDLNRVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSV 493
L +LLDG+ H+ +++ I K + N E ++D+ L + DY KK++
Sbjct: 304 LRYLLDGMRAEEHQRVSKGILKAFGNSTE-----KLDEE-----LKNKVKDYEKKKSMPS 353
Query: 494 IMD-LFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLPIENYWSTKVTIFPQNSPPCTLEV 552
+D +F G S ++C C VS+ + + DL+LP+ + S K ++ +N T+E
Sbjct: 354 FVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQ--SGKKSVNDKNLKK-TVED 410
Query: 553 ELSKTSSYNDLKAYVAQHANM 573
E + D +Y+ + +++
Sbjct: 411 EDQDSEEEKDNDSYIKERSDI 431
Score = 73.6 bits (179), Expect = 2e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 45/191 (23%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQ-----------------HTQASKQIELWNTPD 945
++ CL F++ E L A+ C C + +T A KQ+ + P
Sbjct: 632 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 691
Query: 946 ILLIHLKRFENQRSFSDKIDATVKFPIEGLDMSPYLSYK-----KEGENDVYDLIAVDNH 1000
+L +HLKRF+ K++ +KFP E LD++P+ + K +E +Y L V H
Sbjct: 692 VLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTRVLYSLYGVVEH 750
Query: 1001 YGGLGGGHYTAYCR---------NFI-------------DGKWYYFDDSRVNEVSPENSI 1038
G + GHYTAY + N + G+W++ D+ V V +
Sbjct: 751 SGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVL 810
Query: 1039 AGSAYLLFYRR 1049
AYLLFY R
Sbjct: 811 NSQAYLLFYER 821
>Hs13435157 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 548
Score = 75.1 bits (183), Expect = 7e-13
Identities = 51/144 (35%), Positives = 79/144 (54%), Gaps = 8/144 (5%)
Query: 908 LRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFS-DKIDA 966
L LF + ++L +++ C CK+ ASK+ + T ++L + LKRF N FS KI
Sbjct: 285 LELFVKADVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRFAN---FSGGKITK 341
Query: 967 TVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKWYYFD 1025
V +P E L++ PY+S + G+ +Y L AV H G GHY Y + +G+WY +
Sbjct: 342 DVGYP-EFLNIRPYMS-QNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVK-ASNGQWYQMN 398
Query: 1026 DSRVNEVSPENSIAGSAYLLFYRR 1049
DS V+ + + + AY+LFY R
Sbjct: 399 DSLVHSSNVKVVLNQQAYVLFYLR 422
>At3g14400 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 661
Score = 74.3 bits (181), Expect = 1e-12
Identities = 49/150 (32%), Positives = 79/150 (52%), Gaps = 5/150 (3%)
Query: 901 SITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSF 960
S ++ L+ F Q EIL + + C +C++ A KQ+ + P+IL+I LKRF F
Sbjct: 173 SSSVKESLQKFFQSEILDGNNKYRCESCEKLVTARKQMSILQAPNILVIQLKRFGG--IF 230
Query: 961 SDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDG 1019
KID + F E L +S ++S + Y L + H G GHY AY ++ + G
Sbjct: 231 GGKIDKAISFG-EILVLSNFMSKASKDPQPEYKLFGIIVHSGFSPESGHYYAYVKDSL-G 288
Query: 1020 KWYYFDDSRVNEVSPENSIAGSAYLLFYRR 1049
+WY +DS V+ + + ++ AY+LF+ R
Sbjct: 289 RWYCCNDSFVSLSTLQEVLSEKAYILFFSR 318
>Hs22044528 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 446
Score = 73.9 bits (180), Expect = 1e-12
Identities = 50/150 (33%), Positives = 80/150 (53%), Gaps = 6/150 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
++ L +PE L ++++C C Q ASK + L + +L++ LKRF + +
Sbjct: 148 SVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVT--GN 205
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNH-YGGLGGGHYTAYCRNFIDGKW 1021
KI V++P E LDM PY+S + G VY L AV H GHY +Y + +G+W
Sbjct: 206 KIAKNVQYP-ECLDMQPYMSQQNTGPL-VYVLYAVLVHAEWSCHNGHYFSYVK-AQEGQW 262
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
Y DD+ V S + ++ AY+LFY +++
Sbjct: 263 YKMDDAEVTASSITSVLSQQAYVLFYIQKS 292
Score = 62.8 bits (151), Expect = 3e-09
Identities = 49/189 (25%), Positives = 82/189 (42%), Gaps = 50/189 (26%)
Query: 344 LGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF-GHLLYSLFAP 402
+GNTCY+N++LQCL + P L Y L + + + + HKG + H+ +L P
Sbjct: 1 MGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH-----RHKGCMLCTMQAHITRALHNP 55
Query: 403 SYGQSTFYAPRNFKNTIGHYNSLFAGY---GQQDSQEFLAFLLDGLHEDLNRVIEKPYVN 459
+ I +L AG+ Q+D+ EFL F +D +
Sbjct: 56 GH-------------VIQPSQALAAGFHRGKQEDAHEFLMFTVDAM-------------K 89
Query: 460 KPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFD 519
K P Q+D ++ ++I +F G ++S + C +C+ +S TFD
Sbjct: 90 KACLPRHKQVDH---------------HSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFD 134
Query: 520 PYNDLTLPL 528
PY D+ L +
Sbjct: 135 PYLDIALDI 143
>At1g04860 [O] KOG1873 Ubiquitin-specific protease
Length = 961
Score = 73.9 bits (180), Expect = 1e-12
Identities = 56/194 (28%), Positives = 87/194 (43%), Gaps = 35/194 (18%)
Query: 338 IMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLLY 397
+ GL NLGNTC+ NS +Q LL + L ++FL + N G G +A + L+
Sbjct: 230 VRGLVNLGNTCFFNSIMQNLLSLDRLRDHFLKE---------NGSGVGGPLASSL-RKLF 279
Query: 398 SLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPY 457
+ P G + PR F + F GY Q DS E L LLD L + + + +K
Sbjct: 280 TETKPEAGLKSVINPRAFFGSFCSKAPQFRGYDQHDSHELLRCLLDSLSTEESALRKKRG 339
Query: 458 VNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSIT 517
V+ D D+ ++ ++I +F G S + C C H S
Sbjct: 340 VS-----------DNDE--------------KSTTLIESVFGGETSSIVSCMECGHSSKV 374
Query: 518 FDPYNDLTLPLPIE 531
++P+ DL+LP+P +
Sbjct: 375 YEPFLDLSLPVPFK 388
Score = 68.2 bits (165), Expect = 8e-11
Identities = 45/126 (35%), Positives = 65/126 (50%), Gaps = 11/126 (8%)
Query: 934 ASKQIELWNTPDILLIHLKRF-ENQRSFSDKIDATVKFPIEGLDMSPYLSYKKEGEND-V 991
A+K++ + P +L IHLKRF ++ R K++ V F E +D+ Y+ + GE+ V
Sbjct: 832 ATKKVLINKAPPVLTIHLKRFSQDLRGRLSKLNGHVAFK-EVIDLRQYMDSRCSGEDPPV 890
Query: 992 YDLIAVDNHYGGLGGGHYTAYCRNFIDGK--------WYYFDDSRVNEVSPENSIAGSAY 1043
Y L + H G + GGHY AY R K WY D+ V +VS E + AY
Sbjct: 891 YRLAGLVEHSGTMRGGHYVAYVRGGQRVKETDSSSTAWYNVSDAYVRQVSLEKVLHSEAY 950
Query: 1044 LLFYRR 1049
+LFY R
Sbjct: 951 ILFYER 956
>YNL186w [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 792
Score = 72.8 bits (177), Expect = 3e-12
Identities = 47/154 (30%), Positives = 77/154 (49%), Gaps = 9/154 (5%)
Query: 903 TLDSCLRLFSQPEILG---SADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRS 959
+++ ++ F PE++ + C C + T A K + P+ LL+HLK+F +
Sbjct: 585 SIEKSIKDFFNPELIKVDKEQKGYVCEKCHKTTNAVKHSSILRAPETLLVHLKKFRFNGT 644
Query: 960 FSDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFID 1018
S K+ V +P+ LD++ Y K+ Y L++V H G L GHY A+C+ D
Sbjct: 645 SSSKMKQAVSYPM-FLDLTEYCESKELPVK--YQLLSVVVHEGRSLSSGHYIAHCKQ-PD 700
Query: 1019 GKWYYFDDSRVNEVSPENSI-AGSAYLLFYRRRT 1051
G W +DD +N +S + + +AY L Y R T
Sbjct: 701 GSWATYDDEYINIISERDVLKEPNAYYLLYTRLT 734
>CE26241 [O] KOG1867 Ubiquitin-specific protease
Length = 664
Score = 72.0 bits (175), Expect = 6e-12
Identities = 53/196 (27%), Positives = 84/196 (42%), Gaps = 34/196 (17%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFL-YKGYEREININNPLGHKGDVAH---AFGHL 395
G+ N+GNTC+MN+ LQ L I E EY + E I+ + G+ + + L
Sbjct: 379 GMRNVGNTCFMNAVLQALASISEFREYIMSLSSLEDYIHDEKEPKNGGNYCYLTDEYRKL 438
Query: 396 LYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEK 455
L S A S+ + T AP F+ F G+ Q DS EF+ + +D LH ++ + +
Sbjct: 439 LISQSARSFREPT--APNEFREAFISVCPRFRGFRQHDSHEFMRYFMDSLHTEMRKCRKL 496
Query: 456 PYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVS 515
P G DD + I F G +S+++C C + S
Sbjct: 497 P----------GMPDD------------------KHTPISKYFEGTLQSSVICQTCRNCS 528
Query: 516 ITFDPYNDLTLPLPIE 531
D + DL+L +P +
Sbjct: 529 NKIDEFMDLSLDIPAQ 544
>At4g39910 [O] KOG1864 Ubiquitin-specific protease
Length = 371
Score = 71.2 bits (173), Expect = 9e-12
Identities = 67/206 (32%), Positives = 92/206 (44%), Gaps = 42/206 (20%)
Query: 874 VNWDHPAILENLSLSEVRKTRAQT----------------EKSSITLDSCLRLFSQPEIL 917
V W H I + + +E R R +T + SSIT SCL+ FS E L
Sbjct: 169 VTWVHN-IFQGILTNETRCLRCETVTARDETFLDLSLDIEQNSSIT--SCLKNFSSTETL 225
Query: 918 GSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFE--NQRSFSDKIDATVKFPIEGL 975
+ D ++C C +A K++++ P IL+IHLKRF+ Q K+ V FP+E
Sbjct: 226 HAEDKFFCDKCCSLQEAQKRMKIKKPPHILVIHLKRFKYIEQLGRYKKLSYRVVFPLE-- 283
Query: 976 DMSPYLSYKKEGENDV-YDLIAVDNHYG-GLGGGHYTAYCRNFIDGKWYYFDDSRVN--E 1031
LS E DV Y L AV H G G GHY + ++ W +FDD V E
Sbjct: 284 ---LKLSNTVEPYADVEYSLFAVVVHVGSGPNHGHYVSLVKS--HNHWLFFDDENVEMIE 338
Query: 1032 VSPENSIAGSA----------YLLFY 1047
S + GS+ Y+LFY
Sbjct: 339 ESAVQTFFGSSQEYSSNTDHGYILFY 364
>At2g22310 [O] KOG1864 Ubiquitin-specific protease
Length = 365
Score = 69.3 bits (168), Expect = 4e-11
Identities = 59/184 (32%), Positives = 88/184 (47%), Gaps = 29/184 (15%)
Query: 874 VNWDHPAILENLSLSEVRKTRAQT----------------EKSSITLDSCLRLFSQPEIL 917
V W H I + + +E R R +T + SSIT SCL+ FS E L
Sbjct: 164 VTWVHK-IFQGILTNETRCLRCETVTARDETFLDLSLDIEQNSSIT--SCLKNFSSTETL 220
Query: 918 GSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFE--NQRSFSDKIDATVKFPIEGL 975
+ D ++C C +A K++++ P IL+IHLKRF+ Q K+ V FP+E L
Sbjct: 221 HAEDKFFCDKCCSLQEAQKRMKIKKPPHILVIHLKRFKYMEQLGRYKKLSYRVVFPLE-L 279
Query: 976 DMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSP 1034
+S + + E Y L AV H G G GHY + ++ W +FDD V E+
Sbjct: 280 KLSNTVDEYVDIE---YSLFAVVVHVGSGPNHGHYVSLVKS--HNHWLFFDDESV-EIIE 333
Query: 1035 ENSI 1038
E+++
Sbjct: 334 ESAV 337
Score = 55.5 bits (132), Expect = 5e-07
Identities = 49/189 (25%), Positives = 78/189 (40%), Gaps = 11/189 (5%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLLYSL 399
G N GNTCY NS LQ L E L E NN + ++ L +S
Sbjct: 24 GFENFGNTCYCNSVLQALYFCAPFREQLL------EHYANNKADAEENLLTCLADL-FSQ 76
Query: 400 FAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYVN 459
+ ++ AP+ F + N LF Y QD+ EFL +LL+ L E L + + +
Sbjct: 77 ISSQKKKTGVIAPKRFVQRLKKQNELFRSYMHQDAHEFLNYLLNELVEILEKETQATKAD 136
Query: 460 KPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFD 519
+ +I + VL A K+ + + +F G+ + C C V+ +
Sbjct: 137 NETSSSPEKIAN----VLKAPLANGVHKEPIVTWVHKIFQGILTNETRCLRCETVTARDE 192
Query: 520 PYNDLTLPL 528
+ DL+L +
Sbjct: 193 TFLDLSLDI 201
>Hs18860907_1 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 622
Score = 68.9 bits (167), Expect = 5e-11
Identities = 43/132 (32%), Positives = 70/132 (52%), Gaps = 6/132 (4%)
Query: 904 LDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKR--FENQRSFS 961
L C+ F + E L + ++C NC+ A+++I L + P L + L R F+ Q
Sbjct: 249 LTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHK 308
Query: 962 DKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGK 1020
K++ + F E LDM PY+ +K G + VY+L AV H G GHY A+ ++ G+
Sbjct: 309 KKLNTYIGFS-EILDMEPYVEHK--GGSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGE 365
Query: 1021 WYYFDDSRVNEV 1032
WY F+D + ++
Sbjct: 366 WYKFNDEDIEKM 377
>ECU07g0410 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 295
Score = 68.6 bits (166), Expect = 6e-11
Identities = 54/203 (26%), Positives = 86/203 (41%), Gaps = 49/203 (24%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLLYSL 399
GL N GNTC+ NSA+QC+L I ELN ++ + R+ I+N +
Sbjct: 14 GLRNKGNTCFFNSAMQCILSIGELNTFYKNTDFPRDKPISN---------------AFKQ 58
Query: 400 FAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYVN 459
F Y + P++F + + LF G QQDS EFL +D LH + +
Sbjct: 59 FIAEYETPGCHDPKSFIDKLSGRIKLFNGM-QQDSHEFLIQFIDLLHNESD--------- 108
Query: 460 KPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITF- 518
N +++ D ++ + R S++ + K L C CN+ S+T
Sbjct: 109 ----GNKSRLESKD----------EFEEVRKHSLVAKTLFSMDKQVLTCEACNYSSVTIA 154
Query: 519 -------DPYNDLTLPLPIENYW 534
+PY T+ L I+ Y+
Sbjct: 155 MNSTILVEPYE--TVQLGIDRYY 175
Score = 53.9 bits (128), Expect = 2e-06
Identities = 37/134 (27%), Positives = 59/134 (43%), Gaps = 23/134 (17%)
Query: 917 LGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQ---RSFSDKIDATVKFPIE 973
L D+W C C + + K++E+ PD+L++H+ RF Q + S +++ T+ F
Sbjct: 180 LEGKDAWRCDKCGRKESSRKRMEVLVHPDVLIVHISRFHPQGWKNTASVEVNDTLLF--- 236
Query: 974 GLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVS 1033
N Y L+ V G L GGHY A + G W ++D +V + S
Sbjct: 237 --------------NNRKYSLLGVVCQNGTLNGGHYFAEAKR--SGTWNVYNDEQVTKGS 280
Query: 1034 PENSIAGSAYLLFY 1047
S Y+ FY
Sbjct: 281 RTYS-GSHPYIAFY 293
>Hs20548613 [O] KOG1864 Ubiquitin-specific protease
Length = 370
Score = 67.8 bits (164), Expect = 1e-10
Identities = 51/167 (30%), Positives = 80/167 (47%), Gaps = 19/167 (11%)
Query: 899 KSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFE--N 956
+ + ++ CLR FS E L S +YC C+ +A K++++ P IL +HLKRF+ +
Sbjct: 207 EQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMD 266
Query: 957 QRSFSDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRN 1015
Q K+ V FP+E + S + +YDL+AV H G G GHY A ++
Sbjct: 267 QLHRYTKLSYRVVFPLELRLFN--TSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKS 324
Query: 1016 FIDGKWYYFDDSRVNEVSPE------------NSIAGSAYLLFYRRR 1050
W FDD V ++ + + + S Y+LFY+ R
Sbjct: 325 --HDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSR 369
Score = 52.0 bits (123), Expect = 6e-06
Identities = 50/188 (26%), Positives = 76/188 (39%), Gaps = 24/188 (12%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFL-YKGYEREININNPLGHKGDVAHAFGHLLYS 398
GL N GNTCY NS LQ L E L YK R+ K + L +S
Sbjct: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRK---------KESLLTCLADLFHS 90
Query: 399 LFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYV 458
+ A + P+ F + N LF Y QQD+ EFL +LL+ + D+ + K
Sbjct: 91 I-ATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTI-ADILQEERKQEK 148
Query: 459 NKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITF 518
PN G ID+ + + + + ++F G + C C +S
Sbjct: 149 QNGRLPN-GNIDNENN-----------NSTPDPTWVHEIFQGTLTNETRCLTCETISSKD 196
Query: 519 DPYNDLTL 526
+ + DL++
Sbjct: 197 EDFLDLSV 204
>Hs14732941 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 404
Score = 67.4 bits (163), Expect = 1e-10
Identities = 38/117 (32%), Positives = 57/117 (48%), Gaps = 2/117 (1%)
Query: 936 KQIELWNTPDILLIHLKRFENQRSFSDKIDATVKFPIEGLDMSPYLSYKKEG--ENDVYD 993
K+ +L P L+ +KRF F +K V FPI +D+ YLS + + +N YD
Sbjct: 278 KRFQLTKLPPYLIFCIKRFTKNNFFVEKNPTIVNFPITNVDLREYLSEEVQAVHKNTTYD 337
Query: 994 LIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRR 1050
LIA H G G Y + + GKWY D +V ++ P+ AY+ ++RR
Sbjct: 338 LIANIVHDGKPSEGSYRIHVLHHGTGKWYELQDLQVTDILPQMITLSEAYIQIWKRR 394
>Hs12383078 [O] KOG1864 Ubiquitin-specific protease
Length = 366
Score = 67.0 bits (162), Expect = 2e-10
Identities = 51/168 (30%), Positives = 79/168 (46%), Gaps = 21/168 (12%)
Query: 899 KSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRF---E 955
+ + ++ CLR FS E L S +YC C +A K++ + P +L +HLKRF E
Sbjct: 203 EQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMVLALHLKRFKYME 262
Query: 956 NQRSFSDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCR 1014
R ++ K+ V FP+E + S + +YDL+AV H G G GHY +
Sbjct: 263 QLRRYT-KLSYRVVFPLELRLFN--TSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVK 319
Query: 1015 NFIDGKWYYFDDSRVNEVSPE------------NSIAGSAYLLFYRRR 1050
+ G W FDD V ++ + + + S Y+LFY+ R
Sbjct: 320 S--HGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSR 365
Score = 53.5 bits (127), Expect = 2e-06
Identities = 49/190 (25%), Positives = 81/190 (41%), Gaps = 28/190 (14%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFL-YKGYEREININNPLGHKGDVAHAFGHLLYS 398
GL N GNTCY NS LQ L E L YK +++ K ++ L +S
Sbjct: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKK---------KENLLTCLADLFHS 86
Query: 399 LFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYV 458
+ A + P+ F + + N LF Y QQD+ EFL +LL+ + + L
Sbjct: 87 I-ATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQE------- 138
Query: 459 NKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSV--IMDLFVGLYKSTLVCPNCNHVSI 516
K + +G++ + NM + + + + ++F G + C NC VS
Sbjct: 139 EKKQEKQNGKLKN--------GNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSS 190
Query: 517 TFDPYNDLTL 526
+ + DL++
Sbjct: 191 KDEDFLDLSV 200
>CE11978 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 555
Score = 67.0 bits (162), Expect = 2e-10
Identities = 38/119 (31%), Positives = 60/119 (49%), Gaps = 4/119 (3%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
+L+SCL F Q L + + C C+ A+K + P++++I LKRF + S
Sbjct: 390 SLESCLDRFFQNSTLQDDNQYSCSKCEVLVDATKSTKAHRLPEVIIIQLKRFRHTMFGSC 449
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGK 1020
K+ V+FP+ D + + GE +YDL+ H G L GHY +YCR+ D +
Sbjct: 450 KVGKVVEFPLRSQDFGRWTT---SGEPALYDLVGFVVHEGRSLEFGHYVSYCRHEQDNQ 505
>YIL156w [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 1071
Score = 66.6 bits (161), Expect = 2e-10
Identities = 62/240 (25%), Positives = 99/240 (40%), Gaps = 29/240 (12%)
Query: 310 VVEVKQKSSNQHWPSNFFHYNKL-NAPS-----------GIMGLSNLGNTCYMNSALQCL 357
+++ K++ +QH+ + N P+ I GL NLGNTCY+NS +QCL
Sbjct: 568 IIQRKRQHQHQHYDQQILQPQRAYNIPTIERSPNVYVSLSITGLRNLGNTCYINSMIQCL 627
Query: 358 LHIPELNEYFL---YKGYEREININNPLGHKGDVAHAFGHLLYSLFAPSY-GQSTFYAPR 413
F+ YK Y + I N + + L LF Y P
Sbjct: 628 FAAKTFRTLFISSKYKSYLQPIRSNG-----SHYSPKLSNSLSMLFNKMYLNGGCSVVPT 682
Query: 414 NFKNTIGHYN-SLFAGYGQQDSQEFLAFLLDGLHEDLN--RVIEKPYVNKPEFPNDG-QI 469
F I L QQD+QEFL LLD LH++L+ + + Y N + D ++
Sbjct: 683 GFLKVINQLRPDLKIPDDQQDTQEFLMILLDRLHDELSDQQHVANDYPNLLLYNADALKV 742
Query: 470 DDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLP 529
+ + N + S I D+F G +++L C C + + + + L+L +P
Sbjct: 743 SNNEYKHWFDKN----VIGNGISPIDDIFQGQMENSLQCKRCGYTTFNYSTFYVLSLAIP 798
>SPBC1703.12 [O] KOG1864 Ubiquitin-specific protease
Length = 585
Score = 66.6 bits (161), Expect = 2e-10
Identities = 74/286 (25%), Positives = 120/286 (41%), Gaps = 52/286 (18%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFE--NQRSF 960
++ SCLR FS E+L S + ++C CK +A K++++ P IL +HLKRF+ +
Sbjct: 269 SVTSCLRSFSASEMLSSKNKFHCDVCKSLQEAEKRMKIKKLPKILSLHLKRFKYNETQEG 328
Query: 961 SDKIDATVKFPIEGLDMSPYLSYK-KEGENDVYDLIAVDNHY-GGLGGGHYTAYCRNFID 1018
DK+ T+ F E M + + + E +Y L +V H GG GHY + R
Sbjct: 329 HDKLFYTIVFTNE---MRLFTTTEDAENAERMYYLSSVIVHVGGGPHRGHYVSIVRTKTY 385
Query: 1019 GKWYYFDDSRVNEVSPENSIAGSAYLLFYRRRTSGNQTLGNGKLRDIIDISRKEYEQKQD 1078
G W FDD V V+ EN Y +R G+Q
Sbjct: 386 G-WVLFDDENVTPVN-EN----------YLQRFFGDQ----------------------- 410
Query: 1079 EFMTNVETLYAATHTDTESEASDSDRSSVDEEMDSDNSDCENDKKSAFVDQSDISSNSLG 1138
T Y +T + E D D S VD + + K V+ S++SS
Sbjct: 411 ---PGQATAYVLFYTAADEE--DDDVSEVDTKESIKPMSIPSQLKQESVEVSNLSSTPRS 465
Query: 1139 MDNLTYSNRPSKDNTI--HTSKNANGSIESTLNNNELPEAEQTVTA 1182
+TY P D + +S+ ++ +++ +N+ + E ++ A
Sbjct: 466 NSTITY---PDMDPMVASFSSQYSHKTLDRDINSRSYFDREPSLDA 508
>SPAC13A11.04c [O] KOG1867 Ubiquitin-specific protease
Length = 449
Score = 66.6 bits (161), Expect = 2e-10
Identities = 49/200 (24%), Positives = 78/200 (38%), Gaps = 39/200 (19%)
Query: 329 YNKLNAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDV 388
Y + A +G+ G+ NLG TC+M+ LQ +LH P + F + G+ + P +
Sbjct: 135 YPPVCATAGLRGIQNLGATCFMSVILQSILHNPLVRNLF-FSGFHTSTDCKRPTC----M 189
Query: 389 AHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHED 448
A + S++ S +STFY P N + + GY QQD EF +LLD +H +
Sbjct: 190 TCAIDDMFSSIYN-SKNKSTFYGPTAVLNLMWKLSKSLCGYSQQDGHEFFVYLLDQMHTE 248
Query: 449 LNRVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVC 508
P I +F G K+ + C
Sbjct: 249 SGGGTSMPCT---------------------------------CPIHRIFSGSLKNVVTC 275
Query: 509 PNCNHVSITFDPYNDLTLPL 528
+C + DP D++L +
Sbjct: 276 LDCKKERVAVDPLMDISLDI 295
Score = 65.9 bits (159), Expect = 4e-10
Identities = 48/149 (32%), Positives = 66/149 (44%), Gaps = 13/149 (8%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFE-NQRSFS 961
TL CL F E + + C +C A KQ+ P + + LKRFE N + S
Sbjct: 299 TLQGCLERFVSKEKV----QYSCHSCGSKN-AIKQLVFDKLPPTICMQLKRFEQNNFAMS 353
Query: 962 DKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKW 1021
KID V +P + Y ++ Y L +V H G L GHY AY + +W
Sbjct: 354 TKIDKQVSYPA-----FLRMRYNFNQDDVDYQLYSVVCHKGTLDTGHYIAY--TYYQNQW 406
Query: 1022 YYFDDSRVNEVSPENSIAGSAYLLFYRRR 1050
+ DD+ + EV + AYLLFY R
Sbjct: 407 FLLDDTTIVEVKESEVLNSQAYLLFYHER 435
>7295432 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 577
Score = 65.9 bits (159), Expect = 4e-10
Identities = 55/190 (28%), Positives = 87/190 (44%), Gaps = 32/190 (16%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFL-YKGYEREININNPLGHKGDVAHAFGHLLYS 398
G+ N+GNTCY+NS LQ LLHIP L + + + + + N+ P G + A L +
Sbjct: 173 GMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLADCNVAEP--GSGCIICAMTKTLLA 230
Query: 399 LFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYV 458
+ F K H + G Q+D+ EFL FL++ + E+ Y+
Sbjct: 231 TQSNQSAVRPFLIYSKLKQICKH---MVVG-RQEDAHEFLRFLVEAM--------ERAYL 278
Query: 459 NKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITF 518
+ F N + DQ+V + + + +F G +S + C +CNHVSITF
Sbjct: 279 MR--FRN---YKELDQLV------------KETTPLGQIFGGYLRSEVRCLSCNHVSITF 321
Query: 519 DPYNDLTLPL 528
+ DL L +
Sbjct: 322 QHFQDLLLDI 331
Score = 54.3 bits (129), Expect = 1e-06
Identities = 39/126 (30%), Positives = 60/126 (46%), Gaps = 8/126 (6%)
Query: 925 CPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSDKIDATVKFPIEGLDMSPYL--S 982
C CK+ A+KQ L P L I LKRF +K+ + F +D+S Y S
Sbjct: 357 CEGCKKKVSATKQFSLERAPITLCIQLKRFS---MIGNKLTKQISFK-SRIDLSKYAARS 412
Query: 983 YKKEGENDVYDLIAVDNHYGGLGG-GHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGS 1041
+ + Y L+++ H G GHYTA + G +Y FDDS V ++ + +
Sbjct: 413 QAAQAQPLTYRLVSMVTHLGASQHCGHYTA-IGSTDTGSFYNFDDSYVRPIAMHSVCNTN 471
Query: 1042 AYLLFY 1047
AY++F+
Sbjct: 472 AYIMFF 477
>ECU03g0580 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 933
Score = 65.1 bits (157), Expect = 7e-10
Identities = 55/181 (30%), Positives = 86/181 (47%), Gaps = 28/181 (15%)
Query: 899 KSSITLDSCLRLFSQPEILGSADSWYCPNCKQH--TQASKQIELWNTPDILLIHLKRF-- 954
K S L L+ + + EIL + + NC++H A K + + P ++ I LKRF
Sbjct: 247 KLSSNLQESLKRYVKSEILDGNNRY---NCEKHGLVDAKKGVMFSSLPPVMFILLKRFNV 303
Query: 955 ENQRSFSDKIDATVKFPIEGLDMSPYL---SYKKEGENDVYDLIAVDNHYGGLGGGHYTA 1011
+ + KI+ +FP + +DM P+L S +KE + YDL +V H G GH+ A
Sbjct: 304 DFETGNGYKINDYFEFP-DSIDMLPFLDRDSKRKEESDATYDLYSVIVHRGDHDEGHFYA 362
Query: 1012 YCRNFIDGKWYYFDDSRVNEVSP----ENSIAG-----------SAYLLFYRRRTSGNQT 1056
Y + I+G+W F+D+ V E E++ G S Y L Y R++ N
Sbjct: 363 YLK--INGRWLKFNDTVVTEAGEMEALEHNFGGRHPYKDRIRDHSGYYLIYLRKSMANDL 420
Query: 1057 L 1057
L
Sbjct: 421 L 421
>Hs22060223 [O] KOG1867 Ubiquitin-specific protease
Length = 102
Score = 64.7 bits (156), Expect = 9e-10
Identities = 37/92 (40%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Query: 988 ENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLF 1046
E YDL AV H+G G G GHYTAYC N G W + +DS++N S E AY+LF
Sbjct: 8 ETFAYDLSAVVMHHGKGFGSGHYTAYCYNTEGGFWVHCNDSKLNVCSVEEVCKTQAYILF 67
Query: 1047 YRRRT-SGNQTLGNGKLRDIIDISRKEYEQKQ 1077
Y +RT GN + L+ + S + + Q
Sbjct: 68 YTQRTVQGNARISETHLQAQVQSSNNDEGRPQ 99
>YER098w [O] KOG1864 Ubiquitin-specific protease
Length = 754
Score = 64.3 bits (155), Expect = 1e-09
Identities = 59/199 (29%), Positives = 91/199 (45%), Gaps = 32/199 (16%)
Query: 904 LDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRF---ENQRSF 960
+ L+ + Q E+L + +YC C +A + + L P IL +HLKRF E Q+S
Sbjct: 515 IQKMLKSYHQREMLNGVNKFYCNKCYGLQEAERMVGLKQLPHILSLHLKRFKYSEEQKS- 573
Query: 961 SDKIDATVKFPIEGLDMSPYLS---YKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNF 1016
+ K+ + +P+ LD+S + YKK Y+L V H G G GHY CRN
Sbjct: 574 NIKLFNKILYPLT-LDVSSTFNTSVYKK------YELSGVVIHMGSGPQHGHYVCICRNE 626
Query: 1017 IDGKWYYFDDSRVNEVSPENSI--------AGSAYLLFYRRRTSGNQTLGNGKLRDIIDI 1068
G W +DD V + E + +AY+LFY + T ++T + +I
Sbjct: 627 KFG-WLLYDDETVESIKEETVLQFTGHPGDQTTAYVLFY-KETQADKTENQNE-----NI 679
Query: 1069 SRKEYEQKQDEFMTNVETL 1087
+Q Q + N+E L
Sbjct: 680 DTSSQDQMQTD--NNIEQL 696
>SPBC713.02c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1129
Score = 63.9 bits (154), Expect = 1e-09
Identities = 49/138 (35%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 899 KSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQ- 957
K TL+ R Q E L + D+ Y A K I + P++L + LKRF+
Sbjct: 371 KGMDTLEDSFRDAIQVETL-TGDNKYYAEGHGLQDAHKGIIFESLPNVLQLQLKRFDYDM 429
Query: 958 -RSFSDKIDATVKFPIEGLDMSPYLSYKKE-GENDVYDLIAVDNHYGGLGGGHYTAYCRN 1015
R KI+ +FP+E +D+ PYLS + E+ VY L V H G L GGHY A +
Sbjct: 430 LRDMMVKINDRHEFPLE-IDLEPYLSETADKSESHVYVLHGVLVHGGDLHGGHYYALIKP 488
Query: 1016 FIDGKWYYFDDSRVNEVS 1033
D W+ FDD RV +
Sbjct: 489 EKDSNWFKFDDDRVTRAT 506
>Hs22047537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 248
Score = 63.9 bits (154), Expect = 1e-09
Identities = 50/193 (25%), Positives = 84/193 (42%), Gaps = 50/193 (25%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF-GHLLYS 398
GL N+GNTCY+N++LQCL + P L Y L + + + + HK + H+ +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH-----RHKCCMLCTMQAHITWP 135
Query: 399 LFAPSYGQSTFYAPRNFKNTIGHYNSLFAGY---GQQDSQEFLAFLLDGLHEDLNRVIEK 455
L +P + I L AG+ Q+D+ EFL F +D +
Sbjct: 136 LHSPGH-------------VIQPSQVLAAGFHRGEQEDAHEFLMFTVDAM---------- 172
Query: 456 PYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVS 515
K P +D+ ++ ++I +F G ++S + C +C+ +S
Sbjct: 173 ---KKAFLPGHKHLDN---------------HSKDTTLIHQIFGGYWRSHINCFHCHGIS 214
Query: 516 ITFDPYNDLTLPL 528
TFDPY D+ L +
Sbjct: 215 DTFDPYLDIALDI 227
>Hs21361749 [O] KOG1867 Ubiquitin-specific protease
Length = 640
Score = 63.9 bits (154), Expect = 1e-09
Identities = 69/283 (24%), Positives = 110/283 (38%), Gaps = 72/283 (25%)
Query: 337 GIMGLSNLGNTCYMNSALQCLLHI-----------PELNEYFLYKGYEREININNP---- 381
G+ GL NLGNTCYMNS LQ L H+ P E+ K + ++
Sbjct: 251 GVTGLRNLGNTCYMNSILQVLSHLQKFRECFLNLDPSKTEHLFPKATNGKTQLSGKPTNS 310
Query: 382 ----LGHKGDVAHAFG---------------------------HL-----LYSLFAPSY- 404
L + D A A H+ L++LF +
Sbjct: 311 SATELSLRNDRAEACEREGFCWNGRASISRSLELIQNKEPSSKHISLCRELHTLFRVMWS 370
Query: 405 GQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYVNKPEFP 464
G+ +P +++ F GY QQD+QEFL LL + ++L
Sbjct: 371 GKWALVSPFAMLHSVWSLIPAFRGYDQQDAQEFLCELLHKVQQEL--------------- 415
Query: 465 NDGQIDDTDQIVLLAANMWDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYNDL 524
+ + T + +L+ + + K+ V+ +F G S + C +CN+ S T +P+ DL
Sbjct: 416 ---ESEGTTRRILIPFSQRK-LTKQVLKVVNTIFHGQLLSQVTCISCNYKSNTIEPFWDL 471
Query: 525 TLPLPIENYWSTKVTIFPQNSPPCTLEVELSKTSSYNDLKAYV 567
+L P E Y + P N C L L+K + L+ +
Sbjct: 472 SLEFP-ERYHCIEKGFVPLNQTECLLTEMLAKFTETEALEGRI 513
Score = 59.7 bits (143), Expect = 3e-08
Identities = 37/90 (41%), Positives = 51/90 (56%), Gaps = 7/90 (7%)
Query: 932 TQASKQIELWNTPDILLIHLKRFE-NQRSFSDKIDATVKFPIEGLDMSPY----LSYKKE 986
++A KQ+ ++ P +L +HLKRF + R+ +KI V F + L M PY + +
Sbjct: 534 SEARKQLMIYRLPQVLRLHLKRFRWSGRNHREKIGVHVVFD-QVLTMEPYCCRDMLSSLD 592
Query: 987 GENDVYDLIAVDNHYG-GLGGGHYTAYCRN 1015
E YDL AV H+G G G GHYTAYC N
Sbjct: 593 KETFAYDLSAVVMHHGKGFGSGHYTAYCYN 622
>At3g49600_2 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1035
Score = 63.9 bits (154), Expect = 1e-09
Identities = 48/167 (28%), Positives = 80/167 (47%), Gaps = 13/167 (7%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKR--FENQRSF 960
+LD+ L + E L + ++C +C A++ I+L P ++ LKR F + +
Sbjct: 221 SLDASLNDYLSLEQLNGDNQYFCGSCNARVDATRCIKLRTLPPVITFQLKRCIFLPKTTA 280
Query: 961 SDKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDG 1019
KI ++ FP + LDM L+ + + YDL AV H G + GHY A+ ++ G
Sbjct: 281 KKKITSSFSFP-QVLDMGSRLAESSQNKL-TYDLSAVLIHKGSAVNSGHYVAHIKDEKTG 338
Query: 1020 KWYYFDDSRVNEVS--PENSIAGSAYLLFYRRRTSGNQTLGNGKLRD 1064
W+ FDD V+E+ P N + S ++ N T +G + D
Sbjct: 339 LWWEFDDEHVSELGKRPCNEASSST------PQSESNGTASSGNITD 379
>7302097 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2778
Score = 63.5 bits (153), Expect = 2e-09
Identities = 49/151 (32%), Positives = 70/151 (45%), Gaps = 23/151 (15%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFE--NQRSF 960
+L L + + E+L AD+++C C + K++ + P +L I LKRFE +R
Sbjct: 1864 SLTESLEQYVKGELLEGADAYHCDKCDKKVVTVKRVCVKKLPPVLAIQLKRFEYDYERVC 1923
Query: 961 SDKIDATVKFPIEGLDMSPYL---SYKKEG-------------ENDVYDLIAVDNHYGGL 1004
+ K + +FP LDM PY K EG E Y+L + H G
Sbjct: 1924 AIKFNDYFEFP-RILDMEPYTVSGLAKLEGEVVEVGDNCQTNVETTKYELTGIVVHSGQA 1982
Query: 1005 GGGHYTAY--CRNFIDGK--WYYFDDSRVNE 1031
GGHY +Y +N +GK WY FDD V E
Sbjct: 1983 SGGHYFSYILSKNPANGKCQWYKFDDGEVTE 2013
>SPCC188.08c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1108
Score = 62.4 bits (150), Expect = 4e-09
Identities = 46/138 (33%), Positives = 66/138 (47%), Gaps = 5/138 (3%)
Query: 899 KSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFEN-- 956
K L+ R + Q E L D+ Y + +A K + + P IL + LKRFE
Sbjct: 354 KGMKNLEDSFRSYIQVETL-EGDNCYFADTYGFQEAKKGVIFESFPPILHLQLKRFEYDF 412
Query: 957 QRSFSDKIDATVKFPIEGLDMSPYLSYKKE-GENDVYDLIAVDNHYGGLGGGHYTAYCRN 1015
+R KI+ +FP+E D +LS + + +N Y L V H G L GHY A +
Sbjct: 413 ERDMMIKINDRYEFPLE-FDAKAFLSPEADQSQNCEYVLYGVLVHSGDLHNGHYYALLKT 471
Query: 1016 FIDGKWYYFDDSRVNEVS 1033
DG WY +DD+RV +
Sbjct: 472 EKDGPWYKYDDTRVTRAT 489
>At3g11910 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1124
Score = 62.0 bits (149), Expect = 6e-09
Identities = 55/183 (30%), Positives = 85/183 (46%), Gaps = 38/183 (20%)
Query: 934 ASKQIELWNTPDILLIHLKRFENQ--RSFSDKIDATVKFPIEGLDMSP----YLSYKKEG 987
A K + + P +L + LKRFE R KI+ +FP++ LD+ YLS +
Sbjct: 383 AKKGVLFIDFPPVLQLQLKRFEYDFMRDTMVKINDRYEFPLQ-LDLDREDGRYLSPDADK 441
Query: 988 E-NDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRV---------------NE 1031
++Y L +V H GG+ GGHY A+ R + +WY FDD RV E
Sbjct: 442 SVRNLYTLHSVLVHSGGVHGGHYYAFIRPTLSDQWYKFDDERVTKEDVKRALEEQYGGEE 501
Query: 1032 VSPENSIA-----------GSAYLLFYRRRTSGNQTLGNGKLRDIIDISR----KEYEQK 1076
P+N+ +AY+L Y R + ++ + N +DI + R KE E+K
Sbjct: 502 ELPQNNPGFNNPPFKFTKYSNAYMLVYIRESDKDKIICNVDEKDIAEHLRVRLKKEQEEK 561
Query: 1077 QDE 1079
+D+
Sbjct: 562 EDK 564
>7290583 [O] KOG1873 Ubiquitin-specific protease
Length = 1126
Score = 62.0 bits (149), Expect = 6e-09
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 22/142 (15%)
Query: 894 RAQTEKSSITLDSCLRLFSQPEILGSADSWYCPNCKQ------------HTQASKQIELW 941
R Q E ++ SCL F+ E++ + C +C Q +T A+KQ+ +
Sbjct: 850 RYQCEDGECSVQSCLNNFTAVELMTGQNKVGCDSCTQRINGSDPKAKSVNTNATKQLLVS 909
Query: 942 NTPDILLIHLKRFE-NQRSFSDKIDATVKFPIEGLDMSPYLSYK--------KEGENDVY 992
+ P +L++HLKRF+ R K+ V +P LD++ + K ++ + +Y
Sbjct: 910 SPPAVLILHLKRFQLGPRCIFRKLTRPVSYP-NLLDIAAFCGSKVKNLPNIDRKQKKLLY 968
Query: 993 DLIAVDNHYGGLGGGHYTAYCR 1014
L V H GG+ GGHYTAY +
Sbjct: 969 ALYGVVEHSGGMYGGHYTAYVK 990
Score = 60.5 bits (145), Expect = 2e-08
Identities = 71/255 (27%), Positives = 103/255 (39%), Gaps = 41/255 (16%)
Query: 338 IMGLSNLGNTCYMNSALQCLLHIP----------ELNEYFLYKGYEREIN---------I 378
+ GL+NLGNTC+ N+ +QCL P E E F+ G I I
Sbjct: 305 VRGLTNLGNTCFFNAVMQCLAQTPFLLSVLKELSEPGEEFILPGGTFTIKDKGDIELPMI 364
Query: 379 NNPLGHKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFL 438
L G + A + L L A G S F PR + + F G Q D+ E L
Sbjct: 365 KGTLSSWGGLTAALANALEELQA---GGSVF-TPRKLFDRLCVKCPQFTGGDQHDAHELL 420
Query: 439 AFLLDGL-HEDL---NRVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVI 494
LL+ + +EDL RVI + K + N + + + D I +
Sbjct: 421 RQLLESVRNEDLKRYQRVILQNLGYKDQDVNSVSEEMRQKCKIYGNQAGDRILRPE---- 476
Query: 495 MDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLPIENYWSTKVTIFPQNSPPCTLEVEL 554
+F G STL C +C++VS + + D++LP+ +E PQ P EL
Sbjct: 477 -QVFRGFLVSTLTCQDCHNVSSRHEYFLDMSLPVAVEKPQP------PQRRKP---SPEL 526
Query: 555 SKTSSYNDLKAYVAQ 569
S TSS + + Q
Sbjct: 527 SLTSSSSSVTPSTGQ 541
>Hs11641425 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2563
Score = 61.6 bits (148), Expect = 7e-09
Identities = 51/159 (32%), Positives = 73/159 (45%), Gaps = 33/159 (20%)
Query: 904 LDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFEN--QRSFS 961
LDS L + + ++L A++++C C + K++ + P +L I LKRF+ +R +
Sbjct: 1744 LDS-LEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECA 1802
Query: 962 DKIDATVKFPIEGLDMSPYL---SYKKEGEN---------------------DVYDLIAV 997
K + +FP E LDM PY K EG+N Y L+ V
Sbjct: 1803 IKFNDYFEFPRE-LDMEPYTVAGVAKLEGDNVNPESQLIQQSEQSESETAGSTKYRLVGV 1861
Query: 998 DNHYGGLGGGHYTAYC--RNFIDG---KWYYFDDSRVNE 1031
H G GGHY +Y RN DG +WY FDD V E
Sbjct: 1862 LVHSGQASGGHYYSYIIQRNGGDGERNRWYKFDDGDVTE 1900
>Hs11641423 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2547
Score = 61.6 bits (148), Expect = 7e-09
Identities = 51/159 (32%), Positives = 73/159 (45%), Gaps = 33/159 (20%)
Query: 904 LDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFEN--QRSFS 961
LDS L + + ++L A++++C C + K++ + P +L I LKRF+ +R +
Sbjct: 1744 LDS-LEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECA 1802
Query: 962 DKIDATVKFPIEGLDMSPYL---SYKKEGEN---------------------DVYDLIAV 997
K + +FP E LDM PY K EG+N Y L+ V
Sbjct: 1803 IKFNDYFEFPRE-LDMEPYTVAGVAKLEGDNVNPESQLIQQSEQSESETAGSTKYRLVGV 1861
Query: 998 DNHYGGLGGGHYTAYC--RNFIDG---KWYYFDDSRVNE 1031
H G GGHY +Y RN DG +WY FDD V E
Sbjct: 1862 LVHSGQASGGHYYSYIIQRNGGDGERNRWYKFDDGDVTE 1900
>CE23923 [O] KOG1864 Ubiquitin-specific protease
Length = 398
Score = 61.6 bits (148), Expect = 7e-09
Identities = 43/147 (29%), Positives = 70/147 (47%), Gaps = 9/147 (6%)
Query: 899 KSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQR 958
+ + ++ CLR+FS+ E L ++C C +A K++ + P +L +HLKRF+
Sbjct: 220 EQNTSISHCLRVFSETETLCGDQKYFCETCSSKQEAQKRMRIKKPPQLLALHLKRFKFVE 279
Query: 959 SFS--DKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGL-GGGHYTAYCRN 1015
+ K+ V FP+E + +S E + +YDL+A H G GHY ++
Sbjct: 280 PLNRHTKLSYRVVFPLELRLFN--VSDDAEYGDRMYDLVATVVHCGATPNRGHYITLVKS 337
Query: 1016 FIDGKWYYFDDSRVN--EVSPENSIAG 1040
+ W FDD V EVS +G
Sbjct: 338 --NSFWLVFDDDIVEKLEVSSMEEFSG 362
>CE23922 [O] KOG1864 Ubiquitin-specific protease
Length = 410
Score = 61.6 bits (148), Expect = 7e-09
Identities = 43/147 (29%), Positives = 70/147 (47%), Gaps = 9/147 (6%)
Query: 899 KSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQR 958
+ + ++ CLR+FS+ E L ++C C +A K++ + P +L +HLKRF+
Sbjct: 232 EQNTSISHCLRVFSETETLCGDQKYFCETCSSKQEAQKRMRIKKPPQLLALHLKRFKFVE 291
Query: 959 SFS--DKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYGGL-GGGHYTAYCRN 1015
+ K+ V FP+E + +S E + +YDL+A H G GHY ++
Sbjct: 292 PLNRHTKLSYRVVFPLELRLFN--VSDDAEYGDRMYDLVATVVHCGATPNRGHYITLVKS 349
Query: 1016 FIDGKWYYFDDSRVN--EVSPENSIAG 1040
+ W FDD V EVS +G
Sbjct: 350 --NSFWLVFDDDIVEKLEVSSMEEFSG 374
Score = 55.5 bits (132), Expect = 5e-07
Identities = 51/236 (21%), Positives = 96/236 (40%), Gaps = 25/236 (10%)
Query: 333 NAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVAHAF 392
NA GL N GNTCY NS +Q L E L Y++ + + K ++
Sbjct: 21 NANEHYYGLVNFGNTCYCNSVIQALFFCRPFREKVL--NYKQTLKKSG--ASKDNLVTCL 76
Query: 393 GHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDL--N 450
L +S+ + T AP+ F + N LF Y QQD+ EF +L++ + E L
Sbjct: 77 ADLFHSIASQKRRVGTI-APKRFITKLKKENELFDNYMQQDAHEFFNYLINTISETLIQE 135
Query: 451 RVIEKPYVNK-----------------PEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSV 493
++ E+ ++ P + +++ + +++ K + +
Sbjct: 136 KIAEREKASRHGTLKKGNVTVNLAPATAGLPRSDEKGTSERNGGITVEGNEFLNKSDTTT 195
Query: 494 -IMDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLPIENYWSTKVTIFPQNSPPC 548
I ++F G+ + C +C VS + + DL++ + S + +F + C
Sbjct: 196 WIHEIFQGILTNETRCLSCETVSSKDEDFLDLSIDVEQNTSISHCLRVFSETETLC 251
>At5g06600 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1115
Score = 61.6 bits (148), Expect = 7e-09
Identities = 53/184 (28%), Positives = 84/184 (44%), Gaps = 39/184 (21%)
Query: 934 ASKQIELWNTPDILLIHLKRFENQ--RSFSDKIDATVKFPIEGLDMS----PYLSYKKEG 987
A K + + P +L + LKRFE R KI+ +FP+E LD+ YLS +
Sbjct: 374 AKKGVLFIDFPPVLQLQLKRFEYDFMRDTMVKINDRYEFPLE-LDLDREDGKYLSPDADR 432
Query: 988 E-NDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIA------- 1039
++Y L +V H GG+ GGHY A+ R + +WY FDD RV + + ++
Sbjct: 433 SVRNLYTLHSVLVHSGGVHGGHYYAFIRPTLSDQWYKFDDERVTKEDLKRALEEQYGGEE 492
Query: 1040 --------------------GSAYLLFYRRRTSGNQTLGNGKLRDIIDISR----KEYEQ 1075
+AY+L Y R + ++ + N +DI + R KE E+
Sbjct: 493 ELPQTNPGFNNNPPFKFTKYSNAYMLVYIRESDKDKIICNVDEKDIAEHLRVRLKKEQEE 552
Query: 1076 KQDE 1079
K+D+
Sbjct: 553 KEDK 556
>Hs22043041 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 959
Score = 60.8 bits (146), Expect = 1e-08
Identities = 61/233 (26%), Positives = 98/233 (41%), Gaps = 66/233 (28%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRF----ENQR 958
+L+ L F + E+L ++++YC CK+ K+ + + P +L+IHL RF E+ R
Sbjct: 176 SLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGR 235
Query: 959 SFSDKIDATVKFPIEGLDMSPYL--------SYKKEGEN-------------------DV 991
S K D ++FP L+M PY S + GEN +
Sbjct: 236 SI--KYDEQIRFPWM-LNMEPYTVSGMARQDSSSEVGENGRSVDQGGGGSPRKKVALTEN 292
Query: 992 YDLIAVDNHYGGLGGGHYTAYC---RNFIDGKWYYFDDSRVNE----------------- 1031
Y+L+ V H G GHY ++ R GKWY F+D+ + E
Sbjct: 293 YELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEY 352
Query: 1032 -------VSPENSIA---GSAYLLFYRRRTSGNQTLGNGKLRDIIDISRKEYE 1074
+P + +AY+LFY+R + N + K R + + R+E E
Sbjct: 353 RPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSR--VSVVRQEAE 403
>Hs20532433 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2555
Score = 60.8 bits (146), Expect = 1e-08
Identities = 55/216 (25%), Positives = 90/216 (41%), Gaps = 45/216 (20%)
Query: 904 LDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFEN--QRSFS 961
LDS L + + ++L A++++C C + K++ + P +L I LKRF+ +R +
Sbjct: 1753 LDS-LEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLKRFDYDWERECA 1811
Query: 962 DKIDATVKFPIEGLDMSPY-------------------LSYKKEGENDV-----YDLIAV 997
K + +FP E LDM PY + K++ +N+ Y L+ V
Sbjct: 1812 IKFNDYFEFPRE-LDMGPYTVAGVANLERDNVNSENELIEQKEQSDNETAGGTKYRLVGV 1870
Query: 998 DNHYGGLGGGHYTAYC--RNFIDGK---WYYFDDSRVNEVSPENSIAGSAYLLFYRRRTS 1052
H G GGHY +Y RN D + WY FDD V E ++
Sbjct: 1871 LVHSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKMDDD------------EEM 1918
Query: 1053 GNQTLGNGKLRDIIDISRKEYEQKQDEFMTNVETLY 1088
NQ G + ++ D K ++ + N L+
Sbjct: 1919 KNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILF 1954
>7295436 [O] KOG4598 Putative ubiquitin-specific protease
Length = 1248
Score = 60.8 bits (146), Expect = 1e-08
Identities = 42/147 (28%), Positives = 67/147 (45%), Gaps = 35/147 (23%)
Query: 973 EGLDMSPYLSYK-KEGEND-VYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVN 1030
EG+DMS S K+G +Y+L A+ H G GGHY AY ++F + +W+ F+D V
Sbjct: 375 EGIDMSSSTSKSAKQGSGPYLYELFAIMIHSGSASGGHYYAYIKDFDNNEWFCFNDQNVT 434
Query: 1031 EVSPEN---SIAG--------------SAYLLFYRRRTSGNQTLGNGKLRDIIDISRKEY 1073
++ E+ S G +AY+L YR+ +D R E
Sbjct: 435 SITQEDIQRSFGGPNGSYYSSAYTSSTNAYMLMYRQ----------------VDAKRNEL 478
Query: 1074 EQKQDEFMTNVETLYAATHTDTESEAS 1100
K +F +++TL H++ E+ S
Sbjct: 479 VAKVADFPEHIKTLLPKLHSEEETRVS 505
>7293523 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 719
Score = 60.8 bits (146), Expect = 1e-08
Identities = 33/117 (28%), Positives = 57/117 (48%), Gaps = 3/117 (2%)
Query: 936 KQIELWNTPDILLIHLKRFENQRSFSDKIDATVKFPIEGLDMSPYLSYK---KEGENDVY 992
K+ E+ P +++++KRF F +K V FPI+ +D L + K+ ++ Y
Sbjct: 362 KRFEITRLPQFIILYIKRFTKNTFFLEKNPTIVNFPIKHVDFGDILGMRQRDKDVKDTKY 421
Query: 993 DLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRR 1049
+L+A H G G Y A+ + +G+WY D V E+ P+ +Y+ Y R
Sbjct: 422 NLVANIVHDGDPKKGTYRAHILHKANGQWYEMQDLHVTEILPQMITLTESYIQIYER 478
>Hs4759296 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2555
Score = 60.1 bits (144), Expect = 2e-08
Identities = 48/159 (30%), Positives = 74/159 (46%), Gaps = 33/159 (20%)
Query: 904 LDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFEN--QRSFS 961
LDS L + + ++L A++++C C + K++ + P +L I LKRF+ +R +
Sbjct: 1753 LDS-LEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLKRFDYDWERECA 1811
Query: 962 DKIDATVKFPIEGLDMSPY-------------------LSYKKEGENDV-----YDLIAV 997
K + +FP E LDM PY + K++ +N+ Y L+ V
Sbjct: 1812 IKFNDYFEFPRE-LDMGPYTVAGVANLERDNVNSENELIEQKEQSDNETAGGTKYRLVGV 1870
Query: 998 DNHYGGLGGGHYTAYC--RNFIDGK---WYYFDDSRVNE 1031
H G GGHY +Y RN D + WY FDD V E
Sbjct: 1871 LVHSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTE 1909
>YKR098c [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 717
Score = 59.7 bits (143), Expect = 3e-08
Identities = 59/210 (28%), Positives = 84/210 (39%), Gaps = 25/210 (11%)
Query: 330 NKLNAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYEREININNPLGHKGDVA 389
N L + I GL N NTCY+NS +QCL + FL K Y +N N K
Sbjct: 289 NDLLSELSITGLQNPCNTCYINSIIQCLFGTTLFRDLFLTKKYRLFLNTN-----KYPKE 343
Query: 390 HAFGHLLYSLFAPSY--GQSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHE 447
+Y LF Y G R K L QQD+QEFL +L +HE
Sbjct: 344 VQLSRSIYVLFKKMYLNGGRAIIPNRFLKMCKKLRPDLNIPDDQQDTQEFLLIVLARIHE 403
Query: 448 DL-NRVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMWDYIKKRNDSVIMD-------LFV 499
+L N + K Y + + + L N Y K +VI D ++
Sbjct: 404 ELSNENVVKYYPDLVSYDANA----------LQVNPSKYEKWYERNVITDGLSPIDHIYR 453
Query: 500 GLYKSTLVCPNCNHVSITFDPYNDLTLPLP 529
G ++ L C C + S ++ + L+L +P
Sbjct: 454 GQLENILKCQRCGNSSYSYSTFYVLSLAIP 483
>CE20660 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 602
Score = 59.7 bits (143), Expect = 3e-08
Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 2/115 (1%)
Query: 936 KQIELWNTPDILLIHLKRFENQRSFSDKIDATVKFPIEGLDMSPYLSYKKEGEN--DVYD 993
K+ EL PD L+I KRF+ + F +K V FPI +D L+ + YD
Sbjct: 470 KRFELLQLPDFLIITYKRFQKNQWFVEKNPTIVNFPIANVDFYDCLAKDARANHKYTTYD 529
Query: 994 LIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYR 1048
L+A H G G+Y + GKW+ +D V ++ P+ + +Y+ +R
Sbjct: 530 LVANVVHEGTFKDGNYRIQIVHEGSGKWFELEDLHVKDLLPQMIVLAESYIQIWR 584
>Hs22045513 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 907
Score = 59.3 bits (142), Expect = 4e-08
Identities = 60/226 (26%), Positives = 97/226 (42%), Gaps = 33/226 (14%)
Query: 311 VEVKQKSSNQHWPSNFFHYNKLNAPSG------IMGLSNLGNTCYMNSALQCLLHIPELN 364
+ VK+ NQ + +NK P + G SNLGNTCYMN+ LQ L +
Sbjct: 239 LSVKKLRCNQDYTG----WNKPRVPLSSHQQQQLQGFSNLGNTCYMNAILQSLFSLQSFA 294
Query: 365 EYFLYKGYE-REININNPLGHKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYN 423
L +G ++I +N + F HLL + ++ + KN I
Sbjct: 295 NDLLKQGIPWKKIPLN-------ALIRRFAHLLVKKDICN-SETKKDLLKKVKNAISATA 346
Query: 424 SLFAGYGQQDSQEFLAFLLDGLHEDLNRVIEKPYVNKPEFPNDGQIDDTDQIVLLAANMW 483
F+GY Q D+ EFL+ LD L ED+ + + K + +P + D ++A
Sbjct: 347 ERFSGYMQNDAHEFLSQCLDQLKEDMEK-LNKTWKTEPVSGEENSPD-------ISAT-- 396
Query: 484 DYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLP 529
+ VI +L + S ++C C + + +NDL++ LP
Sbjct: 397 ---RAYTCPVITNLEFEVQHS-IICKACGEIIPKREQFNDLSIDLP 438
>Hs22067085 [O] KOG1871 Ubiquitin-specific protease
Length = 798
Score = 57.0 bits (136), Expect = 2e-07
Identities = 45/165 (27%), Positives = 78/165 (47%), Gaps = 17/165 (10%)
Query: 896 QTEKSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFE 955
Q++K D+ L ++ + G Y KQ + S+++ L P +L++HLKRF
Sbjct: 636 QSDKIRTVQDALESLVARESVQG-----YTTKTKQEVEISRRVTLEKLPPVLVLHLKRFV 690
Query: 956 NQRSFS-DKIDATVKFPIEGLD-----MSPYLSYKKEGENDVYDLIAVDNHYGGLG-GGH 1008
+++ K+ +++P++ L+ +SP + K + Y L AV H+G GGH
Sbjct: 691 YEKTGGCQKLIKNIEYPVD-LEISKELLSPGVKNKNFKCHRTYRLFAVVYHHGNSATGGH 749
Query: 1009 YTAYCRNFIDGKWYYFDDSRVNEVSP----ENSIAGSAYLLFYRR 1049
YT W DD V ++ + + +AYLL+YRR
Sbjct: 750 YTTDVFQIGLNGWLRIDDQTVKVINQYQVVKPTAERTAYLLYYRR 794
>7292738 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1129
Score = 57.0 bits (136), Expect = 2e-07
Identities = 46/165 (27%), Positives = 73/165 (43%), Gaps = 23/165 (13%)
Query: 914 PEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSDKIDATVKFPI- 972
PE L D+ Y +ASK + + P +L +HL RF+ I +F
Sbjct: 397 PETL-EGDNKYDAGVHGLQEASKGVIFTSFPPVLHLHLMRFQYDPVTDSSIKYNDRFEFY 455
Query: 973 EGLDMSPYLSYKKEGENDVYDLI--AVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVN 1030
E +++ YL+ E EN + D + AV H G GGHY + DG+W+ FDD V+
Sbjct: 456 EHINLDRYLA---ESENTLADYVLHAVLVHSGDNHGGHYVVFINPKADGRWFKFDDDVVS 512
Query: 1031 EVSPENSI----------------AGSAYLLFYRRRTSGNQTLGN 1059
+ +I +AY+L Y R++ ++ LG+
Sbjct: 513 SCRKQEAIEQNYGGMDDEISFHAKCSNAYMLVYIRQSELDRVLGD 557
>YBL067c [O] KOG1864 Ubiquitin-specific protease
Length = 688
Score = 56.6 bits (135), Expect = 2e-07
Identities = 42/157 (26%), Positives = 75/157 (47%), Gaps = 16/157 (10%)
Query: 904 LDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFE--NQRSFS 961
+ L+ + Q E+L ++ +YC C +A + + L PD L +HLKRF+ +++ +
Sbjct: 516 IQEILKSYHQREMLNGSNKFYCDECCGLQEAERLVGLKQLPDTLTLHLKRFKYSEKQNCN 575
Query: 962 DKIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHY-GGLGGGHYTAYCRNFIDGK 1020
K+ + +P+ L++ ++ K Y+L + H GG GHY + C++ G
Sbjct: 576 IKLFNNIHYPLT-LNVCSSINSK---VCQKYELAGIVVHMGGGPQHGHYVSLCKHEKFG- 630
Query: 1021 WYYFDDSRVNEVSPENSI--------AGSAYLLFYRR 1049
W FDD V V E + +AY+ F +R
Sbjct: 631 WLLFDDETVEAVKEETVLEFTGESPNMATAYVCFIKR 667
>CE13299 [O] KOG4598 Putative ubiquitin-specific protease
Length = 1292
Score = 56.6 bits (135), Expect = 2e-07
Identities = 32/79 (40%), Positives = 43/79 (53%), Gaps = 14/79 (17%)
Query: 984 KKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSP---ENSIAG 1040
K G+N VY+L +V H G GGHY AY +N +WY F+D+RV+ +P E S G
Sbjct: 363 KTSGDN-VYELFSVMVHSGNAAGGHYFAYIKNLDQDRWYVFNDTRVDFATPLEIEKSFGG 421
Query: 1041 ----------SAYLLFYRR 1049
+AY+L YRR
Sbjct: 422 HPSGWNQSNTNAYMLMYRR 440
>Hs22044589 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 449
Score = 55.8 bits (133), Expect = 4e-07
Identities = 39/113 (34%), Positives = 58/113 (50%), Gaps = 5/113 (4%)
Query: 903 TLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRSFSD 962
++ L +PE L ++++C C Q ASK + L + +L++ LKRF + +
Sbjct: 340 SVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVT--GN 397
Query: 963 KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAYCR 1014
KI V++P E LDM PY+S+ G VY L AV H G GHY Y +
Sbjct: 398 KIAKNVQYP-ECLDMQPYMSHTNTGPL-VYVLYAVLVHAGWSCYNGHYFFYVK 448
>Hs13994268 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 913
Score = 55.5 bits (132), Expect = 5e-07
Identities = 60/215 (27%), Positives = 84/215 (38%), Gaps = 50/215 (23%)
Query: 340 GLSNLGNTCYMNSALQCLLHIPELNEYFLYKGYE-REININNPLGHKGDVAHAFGHLLYS 398
GL NLGNTCYMN+ LQ LL IP + L + + +I +N + LL+
Sbjct: 296 GLPNLGNTCYMNAVLQSLLSIPSFADDLLNQSFPWGKIPLN-------ALTMCLARLLF- 347
Query: 399 LFAPSYG-QSTFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLLDGLHEDLNRV--IEK 455
F +Y + N K I +F G Q D+ EFLA LD L +++ ++ I K
Sbjct: 348 -FKDTYNIEIKEMLLLNLKKAISAAAEIFHGNAQNDAHEFLAHCLDQLKDNMEKLNTIWK 406
Query: 456 P--YVNKPEFPNDGQIDDTD--------------------------QIVL-------LAA 480
P + FP DD D Q++L L+
Sbjct: 407 PKSEFGEDNFPKQVFADDPDTSGFSCPVITNFELELLHSIACKACGQVILKTELNNYLSI 466
Query: 481 NMWDYIKKRNDSV--IMDLFVGLYKSTLVCPNCNH 513
N+ IK S+ DLF G + C C H
Sbjct: 467 NLPQRIKAHPSSIQSTFDLFFGAEELEYKCAKCEH 501
>SPBP8B7.21 [O] KOG1871 Ubiquitin-specific protease
Length = 512
Score = 55.1 bits (131), Expect = 7e-07
Identities = 50/175 (28%), Positives = 80/175 (45%), Gaps = 25/175 (14%)
Query: 896 QTEKSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFE 955
Q E +D+ L + PEIL W+ + K + A+KQ+ + + P +L++HLKRF
Sbjct: 344 QAEDIHSVIDA-LEHMTAPEIL---PEWH--SSKGNVTATKQMYIESLPPVLILHLKRFF 397
Query: 956 NQRS-FSDKIDATVKFPIE-GLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGGHYTAY 1012
+ S + K + +P + + + + + YDL AV H+G GGHYT
Sbjct: 398 YEASGGTQKNYKPIAYPARLSIPQNVFSPSVRGSIHPEYDLNAVVYHHGTSASGGHYTVD 457
Query: 1013 CRNFIDGKWYYFDDSRVNEV---SPENSIAGS-------------AYLLFYRRRT 1051
+ W+ DD+ ++ V ENS + AYLLFY RR+
Sbjct: 458 VQQLDKSGWFRIDDTHIHRVPIHDVENSELSADPSLSKLGHGDRVAYLLFYTRRS 512
>Hs22047539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 438
Score = 55.1 bits (131), Expect = 7e-07
Identities = 42/119 (35%), Positives = 63/119 (52%), Gaps = 6/119 (5%)
Query: 934 ASKQIELWNTPDILLIHLKRFENQRSFSDKIDATVKFPIEGLDMSPYLSYKKEGENDVYD 993
A K+ L IL++ KRF + +KI V++P E LDM PY+S + G VY
Sbjct: 171 AMKKACLPGHKQILILVWKRFSDVTG--NKIAKNVQYP-ECLDMQPYMSQQNTGPL-VYV 226
Query: 994 LIAVDNHYG-GLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRRT 1051
L AV H G GHY +Y + +G+WY DD+ V + ++ AY+LFY +++
Sbjct: 227 LYAVLVHAGWSCHNGHYFSYVK-VQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKS 284
>Hs20483065 [O] KOG1864 Ubiquitin-specific protease
Length = 749
Score = 55.1 bits (131), Expect = 7e-07
Identities = 55/200 (27%), Positives = 81/200 (40%), Gaps = 46/200 (23%)
Query: 897 TEKSSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFE- 955
+E S LD + F PE L + + +YC +C A K +EL P L++ L RF
Sbjct: 486 SEGSRSVLD-LVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSF 544
Query: 956 -----NQRSFSD--KIDATVKFPIEGLDMSPYLSYKKEGENDVYDLIAVDNHYG-GLGGG 1007
+R D I ++ P+ G G YDL +V H G G
Sbjct: 545 DLRTMRRRKILDDVSIPLLLRLPLAG------------GRGQAYDLCSVVVHSGVSSESG 592
Query: 1008 HYTAYCRNFI---------------DGKWYYFDDSRVNEVSPENSI-------AGSAYLL 1045
HY Y R + +WY F+D+RV+ S E+ +AY+L
Sbjct: 593 HYYCYAREGAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVL 652
Query: 1046 FYRR--RTSGNQTLGNGKLR 1063
FYR+ R LG+ ++R
Sbjct: 653 FYRQRPREGPEAELGSSRVR 672
Score = 53.9 bits (128), Expect = 2e-06
Identities = 57/227 (25%), Positives = 88/227 (38%), Gaps = 44/227 (19%)
Query: 313 VKQKSSNQHWPSN------FFHYNKLNAPSGIMGLSNLGNTCYMNSALQCLLHIPELNEY 366
+KQ W S F+ + +G +GL NLGNTCY+NS LQ L +
Sbjct: 140 IKQLLGQDAWTSQKSELAGFYPRLMAKSDTGKIGLINLGNTCYVNSILQALFMASDFRHC 199
Query: 367 FLYKGYEREININNPLGHKGDVAHAFGHLLYSLFAPSYGQSTFYAPRNFKNTIGHYNSLF 426
L + NN + FG L +S Q +P NF + + F
Sbjct: 200 VL------RLTENNSQPLMTKLQWLFGFLEHS-------QRPAISPENFLS--ASWTPWF 244
Query: 427 AGYGQQDSQEFLAFLLDGLHEDL---NRVIEK-PYVNKPEFPNDGQIDDTDQIVLLAANM 482
+ QQD E+L +LLD LHE+ R+ +K + P P +
Sbjct: 245 SPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPEEPPAP------------ 292
Query: 483 WDYIKKRNDSVIMDLFVGLYKSTLVCPNCNHVSITFDPYNDLTLPLP 529
+ + + +F G + + C C +VS + + DL+L P
Sbjct: 293 -------SSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFP 332
>7292313 [O] KOG0944 Ubiquitin-specific protease UBP14
Length = 827
Score = 53.5 bits (127), Expect = 2e-06
Identities = 43/156 (27%), Positives = 68/156 (43%), Gaps = 15/156 (9%)
Query: 299 LKDYDSQIISLVVEVKQKSSNQHWPSNFFHYNKLN--APSGIMGLSNLGNTCYMNSALQC 356
+K + ++ L +++ Q+ W + ++L A G G+ NLGN+CY+NS +Q
Sbjct: 292 MKKSEKSMVELELDINQRIGE--WTALTESESELQPVAGPGYTGMRNLGNSCYINSVMQV 349
Query: 357 LLHIPELNEYFLYKGYEREININNPLGHKGDVAHAFGHLLYSLFAPSYG----------Q 406
L IP+ + F+ G ER P D L L + Y
Sbjct: 350 LFVIPDFQQRFVGTGAERYFK-EFPSDPANDFNIQMAKLGTGLQSGKYSSIAENTLDTDH 408
Query: 407 STFYAPRNFKNTIGHYNSLFAGYGQQDSQEFLAFLL 442
ST +P FKN +G + F+ QQD+ +F LL
Sbjct: 409 STGISPAMFKNIVGKNHPDFSTKQQQDANDFYLHLL 444
>YMR304w [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1230
Score = 53.1 bits (126), Expect = 3e-06
Identities = 35/112 (31%), Positives = 56/112 (49%), Gaps = 13/112 (11%)
Query: 934 ASKQIELWNTPDILLIHLKRFENQRSFSD--KIDATVKFPIEGLDMSPYL---------- 981
A K + + P +L + LKRFE ++ K++ +FP E +D+SP++
Sbjct: 380 AQKGVIFESFPPVLHLQLKRFEYDFNYDQMVKVNDKYEFP-ETIDLSPFVDKDVLKKTLD 438
Query: 982 SYKKEGENDVYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVS 1033
S K+ VY+L V H G + GHY + ++ +WY FDD RV V+
Sbjct: 439 SENKDKNPYVYNLHGVLVHSGDISTGHYYTLIKPGVEDQWYRFDDERVWRVT 490
>7292013_2 [O] KOG1871 Ubiquitin-specific protease
Length = 414
Score = 53.1 bits (126), Expect = 3e-06
Identities = 42/127 (33%), Positives = 58/127 (45%), Gaps = 6/127 (4%)
Query: 929 KQHTQASKQIELWNTPDILLIHLKRFENQRSFSDKIDATVKFPIE-GLDMSPYLSYKKEG 987
KQ A +Q+ L P +L++HLK F+ + KI V FP+E +D S K
Sbjct: 252 KQEVVAWQQMTLEKLPVVLILHLKYFDYRSDGCTKILKKVDFPVELKIDAKILGSKKTSQ 311
Query: 988 ENDVYDLIAVDNHYG-GLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSA---- 1042
+ Y L AV H G GHY + W +DDS V VS ++ +
Sbjct: 312 KQRAYRLFAVVYHDGKEASKGHYITDVFHTGYSSWLRYDDSSVKPVSEKHVLQPHTPRVP 371
Query: 1043 YLLFYRR 1049
YLL+YRR
Sbjct: 372 YLLYYRR 378
>7303452 [O] KOG1864 Ubiquitin-specific protease
Length = 852
Score = 52.8 bits (125), Expect = 3e-06
Identities = 39/164 (23%), Positives = 73/164 (43%), Gaps = 8/164 (4%)
Query: 900 SSITLDSCLRLFSQPEILGSADSWYCPNCKQHTQASKQIELWNTPDILLIHLKRFENQRS 959
++ ++ + + PE L + ++CP CK+ A + I + P L++ LK+F+ +
Sbjct: 585 TNYSVQDLIEYYCSPEKLDGDNQYFCPQCKKLCDAERHIGVTQAPKNLILTLKQFKYDQK 644
Query: 960 FSDKIDATVK-FPIEGLDMSPYLSYKKEGENDV-YDLIAVDNHYG-GLGGGHYTAYCRNF 1016
+ + K F E + + + + V YDL A H G + GHY + +
Sbjct: 645 YHFRTKLMHKVFHDESVTVKMSAKDSLQEMSTVHYDLYAGVVHAGYSMDSGHYFTFAADQ 704
Query: 1017 IDGKWYYFDDSRVNEVSPEN----SIAGSAYLLFYRRRTSGNQT 1056
WY F+D+ V PE + + Y+LFY+ N++
Sbjct: 705 AK-NWYKFNDNVVTHSKPEEMHNLTSPNTPYILFYKMCGHSNES 747
>Hs4507857 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1102
Score = 52.4 bits (124), Expect = 5e-06
Identities = 51/187 (27%), Positives = 77/187 (40%), Gaps = 19/187 (10%)
Query: 933 QASKQIELWNTPDILLIHLKRF--ENQRSFSDKIDATVKFPIEGLDMSPYLSYKKEGEND 990
+A K ++ P +L + L RF + Q + KI+ +FP E L + +L +
Sbjct: 388 EAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFP-EQLPLDEFLQKTDPKDPA 446
Query: 991 VYDLIAVDNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSI------------ 1038
Y L AV H G GGHY Y DGKW FDD V+ + E +I
Sbjct: 447 NYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLS 506
Query: 1039 ---AGSAYLLFYRRRTSGNQTLGNGKLRDI-IDISRKEYEQKQDEFMTNVETLYAATHTD 1094
+AY+L Y R + ++ L DI + + E+K+ E E A +
Sbjct: 507 VRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQ 566
Query: 1095 TESEASD 1101
+ A D
Sbjct: 567 VQIVAED 573
>At4g22350 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 477
Score = 52.4 bits (124), Expect = 5e-06
Identities = 32/113 (28%), Positives = 51/113 (44%), Gaps = 5/113 (4%)
Query: 943 TPDILLIHLKRFENQRSFSDKIDATVKFPIEGLDMSPY---LSYKKEGEN--DVYDLIAV 997
+P L+ H+ RF+ F +K V FP++ +++ Y L EGEN Y+LIA
Sbjct: 363 SPRYLMFHMVRFKKNNFFKEKNPTLVNFPVKDMELRDYIPSLPRAPEGENVCSKYNLIAN 422
Query: 998 DNHYGGLGGGHYTAYCRNFIDGKWYYFDDSRVNEVSPENSIAGSAYLLFYRRR 1050
H G G++ + + WY D V E P+ AY+ Y ++
Sbjct: 423 IVHDGKPEDGYFRVFVQRKSQELWYEMQDLHVAETLPQMVELSEAYMQIYEQQ 475
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.133 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,920,149
Number of Sequences: 60738
Number of extensions: 3477507
Number of successful extensions: 12434
Number of sequences better than 1.0e-05: 133
Number of HSP's better than 0.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 89
Number of HSP's that attempted gapping in prelim test: 11855
Number of HSP's gapped (non-prelim): 367
length of query: 1252
length of database: 30,389,216
effective HSP length: 118
effective length of query: 1134
effective length of database: 23,222,132
effective search space: 26333897688
effective search space used: 26333897688
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)