ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0930 good I KOG3071 Lipid transport and metabolism Fatty acyl-CoA elongase/Polyunsaturated fatty acid specific elongation enzyme
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0930 322785 321727 -353
(353 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YCR034w [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 493 e-139
YJL196c [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 355 7e-98
SPAC1B2.03c [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated ... 286 2e-77
YLR372w [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 285 7e-77
SPAC806.09c [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated ... 245 6e-65
At3g06460 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fa... 95 1e-19
CE10286 [I] KOG3072 Long chain fatty acid elongase 91 3e-18
7294765 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 88 2e-17
CE05979 [I] KOG3072 Long chain fatty acid elongase 85 1e-16
7300877 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 83 5e-16
Hs13129088 [I] KOG3072 Long chain fatty acid elongase 80 3e-15
At3g06470 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fa... 80 5e-15
7300878 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 80 6e-15
CE19785 [I] KOG3072 Long chain fatty acid elongase 79 8e-15
CE16144 [I] KOG3072 Long chain fatty acid elongase 79 8e-15
Hs8923312 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fa... 78 2e-14
Hs12232379 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated f... 75 1e-13
7299265 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 75 1e-13
7300933 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 75 2e-13
7299266 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 75 2e-13
7300879 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 74 2e-13
7299264 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 74 2e-13
Hs11464975 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated f... 74 3e-13
7300874 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 74 4e-13
7296847 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 74 4e-13
7302565 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 73 6e-13
7299268 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 71 3e-12
7294075 [I] KOG3072 Long chain fatty acid elongase 71 3e-12
CE10284 [I] KOG3072 Long chain fatty acid elongase 70 6e-12
CE00112 [I] KOG3072 Long chain fatty acid elongase 70 6e-12
7302564 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 68 2e-11
7299267 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 68 2e-11
7298969 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 65 1e-10
Hs13489093 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated f... 64 3e-10
CE22388 [I] KOG3072 Long chain fatty acid elongase 62 1e-09
Hs17454617 [I] KOG3072 Long chain fatty acid elongase 62 2e-09
CE04292 [I] KOG3072 Long chain fatty acid elongase 60 4e-09
7294766 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 53 8e-07
HsM7705799 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated f... 50 7e-06
Hs18561450 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated f... 49 9e-06
>YCR034w [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 347
Score = 493 bits (1270), Expect = e-139
Identities = 232/345 (67%), Positives = 268/345 (77%)
Query: 5 SNTSQYLEDFVEKYPVVMDYVPTVDRPFFNISLWNNFDAIVTKATDGKFIPSQFKFVSGE 64
S +QY E+YP + DY+PT++RPFFNISLW +FD +VT+ T+G+F+PS+F+F++GE
Sbjct: 3 SLVTQYAAPLFERYPQLHDYLPTLERPFFNISLWEHFDDVVTRVTNGRFVPSEFQFIAGE 62
Query: 65 LPLSELYPVLAAIATYYLVIFGGRAVLKNSEPFKXXXXXXXXXXXXXXXXXXXXXXMIEQ 124
LPLS L PVL AI YY++IFGGR +L S+PFK M+EQ
Sbjct: 63 LPLSTLPPVLYAITAYYVIIFGGRFLLSKSKPFKLNGLFQLHNLVLTSLSLTLLLLMVEQ 122
Query: 125 LTPMIIRHGLYYAICNYGAWTQPLVTLYYLNYITKFIEFIDTIFLVLKHKKLTFLHTYHH 184
L P+I++HGLY+AICN GAWTQPLVTLYY+NYI KFIEFIDT FLVLKHKKLTFLHTYHH
Sbjct: 123 LVPIIVQHGLYFAICNIGAWTQPLVTLYYMNYIVKFIEFIDTFFLVLKHKKLTFLHTYHH 182
Query: 185 GATALLCFTQLVGTTAISWVPISLNLGVHVVMYWYYFLAARGIRVWWKEWVTRFQIIQFV 244
GATALLC+TQL+GTT+ISWVPISLNLGVHVVMYWYYFLAARGIRVWWKEWVTRFQIIQFV
Sbjct: 183 GATALLCYTQLMGTTSISWVPISLNLGVHVVMYWYYFLAARGIRVWWKEWVTRFQIIQFV 242
Query: 245 VDICFIYFAVWQKVATDYFPSLPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVYRRQ 304
+DI FIYFAV+QK YFP LPHCG CVGSTTATF+GCAIISSYL LFI+FYI VY+R+
Sbjct: 243 LDIGFIYFAVYQKAVHLYFPILPHCGDCVGSTTATFAGCAIISSYLVLFISFYINVYKRK 302
Query: 305 GTXXXXXXXXXXXXXXXXXNEYVNVDLKNVSTPSPSPAPRKRNTR 349
GT NEYVNVDLKNV TPSPSP P+ R R
Sbjct: 303 GTKTSRVVKRAHGGVAAKVNEYVNVDLKNVPTPSPSPKPQHRRKR 347
>YJL196c [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 310
Score = 355 bits (910), Expect = 7e-98
Identities = 160/280 (57%), Positives = 208/280 (74%), Gaps = 2/280 (0%)
Query: 26 PTVDRPFFNISLWNNFDAIVTKATDGKFIPSQFKFVSGELPLSELYPVLAAIATYYLVIF 85
PT+DRPFFNI LW+ F+ V AT G+F P F+F G+ PLSE PVL IA YY+VIF
Sbjct: 18 PTIDRPFFNIYLWDYFNRAVGWATAGRFQPKDFEFTVGKQPLSEPRPVLLFIAMYYVVIF 77
Query: 86 GGRAVLKNSEPFKXXXXXXXXXXXXXXXXXXXXXXMIEQLTPMIIRHGLYYAICNYGAWT 145
GGR+++K+ +P K M+EQ+ P++ RHGLY+A+CN +WT
Sbjct: 78 GGRSLVKSCKPLKLRFISQVHNLMLTSVSFLWLILMVEQMLPIVYRHGLYFAVCNVESWT 137
Query: 146 QPLVTLYYLNYITKFIEFIDTIFLVLKHKKLTFLHTYHHGATALLCFTQLVGTTAISWVP 205
QP+ TLYYLNY+TKF+EF DT+ +VLKH+KLTFLHTYHHGATALLC+ QLVG TA++WVP
Sbjct: 138 QPMETLYYLNYMTKFVEFADTVLMVLKHRKLTFLHTYHHGATALLCYNQLVGYTAVTWVP 197
Query: 206 ISLNLGVHVVMYWYYFLAARGIRVWWKEWVTRFQIIQFVVDICFIYFAVWQKVATDYFPS 265
++LNL VHV+MYWYYFL+A GIRVWWK WVTR QI+QF++D+ +Y+ ++QK+ YF +
Sbjct: 198 VTLNLAVHVLMYWYYFLSASGIRVWWKAWVTRLQIVQFMLDLIVVYYVLYQKIVAAYFKN 257
Query: 266 --LPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVYRR 303
P C C+GS TA +G AI++SYLFLFI+FYIEVY+R
Sbjct: 258 ACTPQCEDCLGSMTAIAAGAAILTSYLFLFISFYIEVYKR 297
>SPAC1B2.03c [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 334
Score = 286 bits (733), Expect = 2e-77
Identities = 134/280 (47%), Positives = 182/280 (64%), Gaps = 3/280 (1%)
Query: 26 PTVDRPFFNISLWNNFDAIVTKATDGKFIPSQFKFVSGELPLSELYPVLAAIATYYLVIF 85
P++D PF + LW+ F+ + K PS+F+++ G+ P+S+ V+ +I YY++I
Sbjct: 14 PSIDHPF-GVDLWHLFEQLSIKTIGWN--PSEFEYIPGKTPMSQWSSVIVSITAYYVIIL 70
Query: 86 GGRAVLKNSEPFKXXXXXXXXXXXXXXXXXXXXXXMIEQLTPMIIRHGLYYAICNYGAWT 145
GRA++ N +P K ++E++ +R+GL+Y +C+ +T
Sbjct: 71 SGRAIMTNRKPLKQRRLFQLHNFILTIISGALLALLVEEVFRNYMRNGLFYCVCDSRHFT 130
Query: 146 QPLVTLYYLNYITKFIEFIDTIFLVLKHKKLTFLHTYHHGATALLCFTQLVGTTAISWVP 205
Q LVTLYYLNY+TK++E +DT+FL LK K L FLH YHHG TALLCFTQL+G T++ W
Sbjct: 131 QRLVTLYYLNYLTKYLELMDTVFLFLKKKPLAFLHCYHHGITALLCFTQLLGRTSVQWGV 190
Query: 206 ISLNLGVHVVMYWYYFLAARGIRVWWKEWVTRFQIIQFVVDICFIYFAVWQKVATDYFPS 265
I LNL VHV+MY YYFLAA G RVWWK+WVTR QIIQFV+D+ YF + +A YFP
Sbjct: 191 IGLNLYVHVIMYSYYFLAACGRRVWWKQWVTRVQIIQFVLDLILCYFGTYSHIAFRYFPW 250
Query: 266 LPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVYRRQG 305
LPH G C GS A F GC ++SSYLFLFI FYI Y ++G
Sbjct: 251 LPHVGDCSGSLFAAFFGCGVLSSYLFLFIGFYINTYIKRG 290
>YLR372w [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 345
Score = 285 bits (729), Expect = 7e-77
Identities = 138/285 (48%), Positives = 191/285 (66%), Gaps = 6/285 (2%)
Query: 24 YVPTVDRPFFNISLWNNFDAIVTKATDGKFIPSQFKFVSGELPLSELYPVLAAIATYYLV 83
+VP+++ PF I LW F + + + QF+F+ + L+ Y ++ I YY++
Sbjct: 30 HVPSIENPF-GIELWPIFSKVFEYFSG--YPAEQFEFIHNKTFLANGYHAVSIIIVYYII 86
Query: 84 IFGGRAVLK--NSEPFKXXXXXXXXXXXXXXXXXXXXXXMIEQLTPMIIRHGLYYAICNY 141
IFGG+A+L+ N+ P K M+EQL PM+ +GL+++IC+
Sbjct: 87 IFGGQAILRALNASPLKFKLLFEIHNLFLTSISLVLWLLMLEQLVPMVYHNGLFWSICSK 146
Query: 142 GAWTQPLVTLYYLNYITKFIEFIDTIFLVLKHKKLTFLHTYHHGATALLCFTQLVGTTAI 201
A+ LVTLYYLNY+TKF+E IDT+FLVL+ KKL FLHTYHHGATALLC+TQL+G T++
Sbjct: 147 EAFAPKLVTLYYLNYLTKFVELIDTVFLVLRRKKLLFLHTYHHGATALLCYTQLIGRTSV 206
Query: 202 SWVPISLNLGVHVVMYWYYFLAARGIRVWWKEWVTRFQIIQFVVDICFIYFAVWQKVATD 261
WV I LNLGVHV+MYWYYFL++ GIRVWWK+WVTRFQIIQF++D+ F+YFA + A
Sbjct: 207 EWVVILLNLGVHVIMYWYYFLSSCGIRVWWKQWVTRFQIIQFLIDLVFVYFATYTFYAHK 266
Query: 262 YFPS-LPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVYRRQG 305
Y LP+ G+C G+ A G I++SYL LFI+FYI+ Y++ G
Sbjct: 267 YLDGILPNKGTCYGTQAAAAYGYLILTSYLLLFISFYIQSYKKGG 311
>SPAC806.09c [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 328
Score = 245 bits (626), Expect = 6e-65
Identities = 132/300 (44%), Positives = 170/300 (56%), Gaps = 2/300 (0%)
Query: 48 ATDGKFIPSQFKFVSGELPLSELYPVLAAIATYYLVIFGGRAVLKNSEPFKXXXXXXXXX 107
AT GK PS F+F+ + S V I +YYL+I G +++N +P +
Sbjct: 14 ATFGKR-PSSFEFIVNKTRFSSAPVVATIIISYYLLILVGGRIMRNRQPIRLQKIFQYYN 72
Query: 108 XXXXXXXXXXXXXMIEQLTPMIIRHGLYYAICNYGAWTQPLVTLYYLNYITKFIEFIDTI 167
+ EQ+ P I +HG +++ICN AWTQPLV LYY YI+KF+E DT
Sbjct: 73 LTFSIASAILALLIFEQVAPAIYKHGFFFSICNEKAWTQPLVFLYYCAYISKFLELTDTF 132
Query: 168 FLVLKHKKLTFLHTYHHGATALLCFTQLVGTTAISWVPISLNLGVHVVMYWYYFLAARGI 227
FLVL+ K L FLH YHHGATA+L +TQ+VG T+ISW+ I +NL VHV MY+YY+L A+GI
Sbjct: 133 FLVLRKKPLQFLHCYHHGATAVLVYTQIVGRTSISWLIIEINLLVHVTMYYYYYLVAKGI 192
Query: 228 RVWWKEWVTRFQIIQFVVDICFIYFAVWQKVATDYFPSLPHCGSCVGSTTATFSGCAIIS 287
RV WK+WVTRFQI+QF D+ FIYFAV+ +VA G C G A F G A IS
Sbjct: 193 RVPWKKWVTRFQIVQFFADLGFIYFAVYTEVAYRLKFYKACMGHCSGHPLAAFCGLATIS 252
Query: 288 SYLFLFIAFYIEVYRRQGTXXXXXXXXXXXXXXXXXNEYVNVDLKNVSTPSPSPAPRKRN 347
SYL LFI FY Y++ + N DLK +S + S A K N
Sbjct: 253 SYLVLFIVFYHNTYKKNAALKMKAKAAAATKGNSSESS-KNADLKRLSKSNASIAEVKCN 311
>At3g06460 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 298
Score = 95.1 bits (235), Expect = 1e-19
Identities = 59/162 (36%), Positives = 86/162 (52%), Gaps = 11/162 (6%)
Query: 147 PLVTLYYLNYITKFIEFIDTIFLVLKH--KKLTFLHTYHHGATALLCFTQLVGTTAISWV 204
PL + Y++K +EF+DT+ ++L ++L+FLH YHH +LC+ L ++ V
Sbjct: 116 PLFFWAQVFYLSKILEFVDTLLIILNKSIQRLSFLHVYHHATVVILCYLWLRTRQSMFPV 175
Query: 205 PISLNLGVHVVMYWYYFLAARGIRVWWKEWVTRFQIIQFVVDICFIYFAVWQKVATDYFP 264
+ LN VHV+MY YYFL A G R WK+ VT FQ++QF + A W + YF
Sbjct: 176 GLVLNSTVHVIMYGYYFLCAIGSRPKWKKLVTNFQMVQFAFGMGL--GAAWM-LPEHYFG 232
Query: 265 SLPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVYRRQGT 306
S C G T F+G +S L LF F+ + Y + T
Sbjct: 233 S-----GCAGIWTVYFNG-VFTASLLALFYNFHSKNYEKTTT 268
>CE10286 [I] KOG3072 Long chain fatty acid elongase
Length = 274
Score = 90.5 bits (223), Expect = 3e-18
Identities = 72/234 (30%), Positives = 107/234 (44%), Gaps = 22/234 (9%)
Query: 80 YYLVIFGGRAVLKNSEPFKXXXXXXXXXXXXXXXXXXXXXXMIEQLTPMIIRHGLYYAIC 139
Y +VIFG +AV+ N +PF L G + +
Sbjct: 40 YVVVIFGLKAVMTNRKPFDLTGPLNLWNAGLAIFSTLGSLATTFGLLHEFFSRGFFESYI 99
Query: 140 NYGAWTQPLVTLY-YLNYITKFIEFIDTIFLVLKHKKLTFLHTYHHGAT---ALLCFTQL 195
+ G + L ++ +L ++K EF DT+F++L+ K L FLH YHH T A + F
Sbjct: 100 HIGDFYNGLSGMFTWLFVLSKVAEFGDTLFIILRKKPLMFLHWYHHVLTMNYAFMSFEAN 159
Query: 196 VG-TTAISWVPISLNLGVHVVMYWYYFLAARGIRV--WWKEWVTRFQIIQFVVDICFIYF 252
+G T I+W +N VH +MY YY L + G++V W + +T QI+QFV+ FI F
Sbjct: 160 LGFNTWITW----MNFSVHSIMYGYYMLRSFGVKVPAWIAKNITTMQILQFVI-THFILF 214
Query: 253 AVWQKVATDYFPSLPHCGSCVGSTTATFSGCAIIS-SYLFLFIAFYIEVYRRQG 305
V T G V ST + C ++ SY+ LF FY + Y + G
Sbjct: 215 HVGYLAVT---------GQSVDSTPGYYWFCLLMEISYVVLFGNFYYQSYIKGG 259
>7294765 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 442
Score = 88.2 bits (217), Expect = 2e-17
Identities = 53/161 (32%), Positives = 81/161 (49%), Gaps = 21/161 (13%)
Query: 148 LVTLYYLNYITKFIEFIDTIFLVLKHK--KLTFLHTYHHGATALLCFTQLVGT-TAISWV 204
L ++ YI+K +EF DT F +L+ K +L+FLH YHH + C+ + T ++V
Sbjct: 286 LTKAFWWFYISKILEFADTAFFILRQKWSQLSFLHVYHHSTMFVFCWILIKWMPTGSTYV 345
Query: 205 PISLNLGVHVVMYWYYFLAARGIRV----WWKEWVTRFQIIQFVVDICFIYFAVWQKVAT 260
P +N VH++MY YY L+ G RV WWK ++T Q++QF + I+F Q +
Sbjct: 346 PAMINSFVHIIMYGYYALSVLGPRVQRFLWWKRYLTGLQLVQFTI----IFFWASQMLVR 401
Query: 261 DYFPSLPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVY 301
C T T S +LF+F FY++ Y
Sbjct: 402 ----------GCEYGTWITLSMAIYSLPFLFMFGKFYMQKY 432
>CE05979 [I] KOG3072 Long chain fatty acid elongase
Length = 288
Score = 85.1 bits (209), Expect = 1e-16
Identities = 71/269 (26%), Positives = 114/269 (41%), Gaps = 23/269 (8%)
Query: 45 VTKATDGKFIPSQFKFVSGELPLSELYPV-LAAIATYYLVIFGGRAVLKNSEPFKXXXXX 103
V AT G P F G ++ + V + A Y +V+FG + ++N +PF+
Sbjct: 21 VAIATHG---PKNFPDAEGRKFFADHFDVTIQASILYMVVVFGTKWFMRNRQPFQLTIPL 77
Query: 104 XXXXXXXXXXXXXXXXXMIEQLTPMIIRHGLYYAICNYGAWTQPLVTLY-YLNYITKFIE 162
M + I G+ + C +T+ + +L +K E
Sbjct: 78 NIWNFILAAFSIAGAVKMTPEFFGTIANKGIVASYCKVFDFTKGENGYWVWLFMASKLFE 137
Query: 163 FIDTIFLVLKHKKLTFLHTYHHGATALLCFTQLVGTTAISWVPISLNLGVHVVMYWYYFL 222
+DTIFLVL+ + L FLH YHH T + + T + I LN VH MY YYFL
Sbjct: 138 LVDTIFLVLRKRPLMFLHWYHHILTMIYAWYSHPLTPGFNRYGIYLNFVVHAFMYSYYFL 197
Query: 223 AARGIRV--WWKEWVTRFQIIQFVVDICFI----YFAVWQKVATDYFPSLPHCGSCVGST 276
+ IRV + + +T QI+QF++ + Y + D+ PS+ + +T
Sbjct: 198 RSMKIRVPGFIAQAITSLQIVQFIISCAVLAHLGYLMHFTNANCDFEPSVFKLAVFMDTT 257
Query: 277 TATFSGCAIISSYLFLFIAFYIEVYRRQG 305
YL LF+ F+++ Y +G
Sbjct: 258 ------------YLALFVNFFLQSYVLRG 274
>7300877 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 322
Score = 83.2 bits (204), Expect = 5e-16
Identities = 67/248 (27%), Positives = 108/248 (43%), Gaps = 28/248 (11%)
Query: 67 LSELYPVLAAIATYYLVIFG-GRAVLKNSEPFKXXXXXXXXXXXXXXXXXXXXXXMIEQL 125
+S PV+A + Y + G +KN +P I++
Sbjct: 29 MSSPMPVVAVVLVYLAFVLKIGPEYMKNRKPMDLKRIMVFYNAFQVLYSIWMCRTSIQES 88
Query: 126 TPMIIRHGLYYAICNYGAWTQPLVTLY---YLNYITKFIEFIDTIFLVLKHK--KLTFLH 180
M ++ C + +TLY + + +K I+ +DT F VL+ K +++FLH
Sbjct: 89 NVMA---SIFSKKCEINRTREQNLTLYSGAWFYFFSKIIDLLDTTFFVLRKKDNQVSFLH 145
Query: 181 TYHHGATALLCFTQLVGTTAISWVPIS-LNLGVHVVMYWYYFLAARGIR----VWWKEWV 235
YHH T L + L V I LN GVH++MY+YY +AA G + +WWK+++
Sbjct: 146 VYHHTITVLFSWGYLKYAPGEQGVIIGILNSGVHIIMYFYYMVAAMGPQYQKYLWWKKYM 205
Query: 236 TRFQIIQFVVDICFIYFAVWQKVATDYFPSLPHCGSCVGSTTATFSGCAIISSYLFLFIA 295
T Q+IQFV+ + ++ V K C T TF +L+LF
Sbjct: 206 TSIQLIQFVLILGYM-LTVGAK-------------GCNMPKTLTFFFVGNTVIFLYLFGN 251
Query: 296 FYIEVYRR 303
FY + Y++
Sbjct: 252 FYRKTYKK 259
>Hs13129088 [I] KOG3072 Long chain fatty acid elongase
Length = 265
Score = 80.5 bits (197), Expect = 3e-15
Identities = 63/227 (27%), Positives = 96/227 (41%), Gaps = 13/227 (5%)
Query: 78 ATYYLVIFGGRAVLKNSEPFKXXXXXXXXXXXXXXXXXXXXXXMIEQLTPMIIRHGLYYA 137
A Y IFGGR ++ F+ + +++ GL +
Sbjct: 38 ALYAAFIFGGRHLMNKRAKFELRKPLVLWSLTLAVFSIFGALRTGAYMVYILMTKGLKQS 97
Query: 138 ICNYGAWTQPLVTLY-YLNYITKFIEFIDTIFLVLKHKKLTFLHTYHHGATALLCFTQLV 196
+C+ G + P+ + Y ++K E DTIF++L+ +KL FLH YHH L +
Sbjct: 98 VCDQGFYNGPVSKFWAYAFVLSKAPELGDTIFIILRKQKLIFLHWYHHITVLLYSWYSYK 157
Query: 197 GTTAISWVPISLNLGVHVVMYWYYFLAARGIRVWWK--EWVTRFQIIQFVVDICFIYFAV 254
A +++N GVH VMY YY L A G RV K ++T QI Q ++ C + + V
Sbjct: 158 DMVAGGGWFMTMNYGVHAVMYSYYALRAAGFRVSRKFAMFITLSQITQMLMG-CVVNYLV 216
Query: 255 WQKVATDYFPSLPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVY 301
+ + D C F + SYL LF F+ E Y
Sbjct: 217 FCWMQHD---------QCHSHFQNIFWSSLMYLSYLVLFCHFFFEAY 254
>At3g06470 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 278
Score = 80.1 bits (196), Expect = 5e-15
Identities = 46/102 (45%), Positives = 61/102 (59%), Gaps = 6/102 (5%)
Query: 147 PLVTLYYLNYITKFIEFIDTIFLVLKH--KKLTFLHTYHHGATALLCFTQLVGTTAISWV 204
PL + Y++K +EF DTI ++L ++L+FLH YHH ++C+ L T S
Sbjct: 119 PLFFWAQVFYLSKILEFGDTILIILGKSIQRLSFLHVYHHATVVVMCYLWL--RTRQSMF 176
Query: 205 PISL--NLGVHVVMYWYYFLAARGIRVWWKEWVTRFQIIQFV 244
PI+L N VHV+MY YYFL A G R WK VT QI+QFV
Sbjct: 177 PIALVTNSTVHVIMYGYYFLCAVGSRPKWKRLVTDCQIVQFV 218
>7300878 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 295
Score = 79.7 bits (195), Expect = 6e-15
Identities = 72/261 (27%), Positives = 113/261 (42%), Gaps = 64/261 (24%)
Query: 72 PVLAAIATY-YLVIFGGRAVLKNSEPFKXXXXXXXXXXXXXXXXXXXXXXMIEQLTPMII 130
P+L +A Y + V+ G +K+ +PFK L+ ++
Sbjct: 35 PLLGILAFYLFFVLSWGPKFMKDRKPFKLERTLLVYNFFQVA------------LSVWMV 82
Query: 131 RHGLYYAICNYGAWT-QPL-----------VTLYYLNYITKFIEFIDTIFLVLKH--KKL 176
G+ I Y +W QP+ + Y+ Y+ K E +DTIF VL+ +++
Sbjct: 83 YEGV--VIWQYYSWRCQPVDWSRTPKAYREARVVYVYYLAKITELLDTIFFVLRKNDRQV 140
Query: 177 TFLHTYHHGATALLCFTQLVGT---------TAISWVPISLNLGVHVVMYWYYFLAARGI 227
TFLH YHH ++ + GT T I W+ N VH++MY YYFL+A G
Sbjct: 141 TFLHVYHHTVMPMISW----GTSKYYPGGHGTFIGWI----NSFVHIIMYSYYFLSAFGP 192
Query: 228 R----VWWKEWVTRFQIIQFVVDICFIYFAVWQKVATDYFPSLPHCGSCVGSTTATFSGC 283
+ +WWK+++T Q+IQF C + Q + TD P C A F
Sbjct: 193 QMQKYLWWKKYITNLQMIQF----CCAFIHQTQLLYTDC--GYPRWSVCFTLPNAVF--- 243
Query: 284 AIISSYLFLFIAFYIEVYRRQ 304
+ FLF FY + Y+++
Sbjct: 244 -----FYFLFNDFYQKSYKKK 259
>CE19785 [I] KOG3072 Long chain fatty acid elongase
Length = 274
Score = 79.3 bits (194), Expect = 8e-15
Identities = 64/240 (26%), Positives = 107/240 (43%), Gaps = 12/240 (5%)
Query: 67 LSELYPVLAAIATYYLV-IFGGRAVLKNSEPFKXXXXXXXXXXXXXXXXXXXXXXMIEQL 125
+S P+ I YLV I+ G+ ++ + +PF +I +L
Sbjct: 29 MSTFVPLSYKIMIGYLVTIYFGQKLMAHRKPFDLQNTLALWNFGFSLFSGIAAYKLIPEL 88
Query: 126 TPMIIRHGLYYAIC-NYGAWTQPLVTLYYLNYI-TKFIEFIDTIFLVLKHKKLTFLHTYH 183
+ ++ G + C N +T + ++ +K E DT+FLVL+ K + F+H YH
Sbjct: 89 FGVFMKDGFVASYCQNENYYTDASTGFWGWAFVMSKAPELGDTMFLVLRKKPVIFMHWYH 148
Query: 184 HGATALLCFTQLVGTTAISWVPISLNLGVHVVMYWYYFLAARGIRV--WWKEWVTRFQII 241
H T + A + ++LNL VH VMY+Y+ + A I+ +++T QI+
Sbjct: 149 HALTFVYAVVTYSEHQAWARWSLALNLAVHTVMYFYFAVRALNIQTPRPVAKFITTIQIV 208
Query: 242 QFVVDICFIYFAVWQKVATDYFPSLPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVY 301
QFV+ C+I+ + + D P C S G + SYLFLF F+ + Y
Sbjct: 209 QFVIS-CYIFGHLVFIKSADSVP------GCAVSWNVLSIGGLMYISYLFLFAKFFYKAY 261
>CE16144 [I] KOG3072 Long chain fatty acid elongase
Length = 281
Score = 79.3 bits (194), Expect = 8e-15
Identities = 60/183 (32%), Positives = 86/183 (46%), Gaps = 9/183 (4%)
Query: 73 VLAAIATYYLVIFGGRAVLKNSEPFKXXXXXXXXXXXXXXXXXXXXXXMIEQLTPMIIRH 132
V AIA Y +++F + +++ EPF+ M + I +
Sbjct: 70 VQMAIA-YVILVFSIKRFMRDREPFQLTTALRLWNFFLSVFSIYGSWTMFPFMVQQIRLY 128
Query: 133 GLYYAICNYGAWTQPLVTLY--YLNYITKFIEFIDTIFLVLKHKKLTFLHTYHHGATALL 190
GLY C P Y +L ++K +EF+DT FLVL+ K L FLH YHH AT +
Sbjct: 129 GLYGCGCE-ALSNLPSQAEYWLFLTILSKAVEFVDTFFLVLRKKPLIFLHWYHHMATFVF 187
Query: 191 CFTQLVGTTAISWVPISLNLGVHVVMYWYYFLAARGIRVWWK--EWVTRFQIIQFVVDIC 248
+ ++ S V + +NL VH MY YYF + I+V K VT Q+ QF +C
Sbjct: 188 FCSNYPTPSSQSRVGVIVNLFVHAFMYPYYFTRSMNIKVPAKISMAVTVLQLTQF---MC 244
Query: 249 FIY 251
FIY
Sbjct: 245 FIY 247
>Hs8923312 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 296
Score = 78.2 bits (191), Expect = 2e-14
Identities = 53/166 (31%), Positives = 85/166 (50%), Gaps = 42/166 (25%)
Query: 156 YITKFIEFIDTIFLVLKHK--KLTFLHTYHHGATALLCFTQLVGTTAISWVPI------- 206
Y +K +EF+DTIF VL+ K ++TFLH YHH + + + L +W+P
Sbjct: 120 YFSKSVEFLDTIFFVLRKKTSQITFLHVYHHASMFNIWWCVL------NWIPCGQSFFGP 173
Query: 207 SLNLGVHVVMYWYYFLA---ARGIRVWWKEWVTRFQIIQFVVDICFIYFAVWQKVATDYF 263
+LN VH++MY YY L+ + +WWK+++T+ Q++QFV+
Sbjct: 174 TLNSFVHILMYSYYGLSVFPSMHKYLWWKKYLTQAQLVQFVL------------------ 215
Query: 264 PSLPHCGSCVGSTTATFSGCAII-SSYL----FLFIAFYIEVYRRQ 304
++ H S V GC I SSY+ LF+ FY++ YR++
Sbjct: 216 -TITHTMSAVVKPCGFPFGCLIFQSSYMLTLVILFLNFYVQTYRKK 260
>Hs12232379 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 314
Score = 75.5 bits (184), Expect = 1e-13
Identities = 50/160 (31%), Positives = 78/160 (48%), Gaps = 33/160 (20%)
Query: 156 YITKFIEFIDTIFLVLKHK--KLTFLHTYHHGATALLCFTQLVGTTAISWVP-------I 206
+++K +E++DT+F +L+ K +++FLH YHH C + I WV
Sbjct: 132 FVSKGVEYLDTVFFILRKKNNQVSFLHVYHH------CTMFTLWWIGIKWVAGGQAFFGA 185
Query: 207 SLNLGVHVVMYWYYFLAARGIRV----WWKEWVTRFQIIQFVVDICFIYFAVWQKVATDY 262
LN +HV+MY YY L A G + WWK ++T Q+IQF V I +++
Sbjct: 186 QLNSFIHVIMYSYYGLTAFGPWIQKYLWWKRYLTMLQLIQFHVTIGHTALSLYTDCP--- 242
Query: 263 FPSLPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVYR 302
FP H ++ A S++FLF+ FYI Y+
Sbjct: 243 FPKWMH-----------WALIAYAISFIFLFLNFYIRTYK 271
>7299265 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 257
Score = 75.1 bits (183), Expect = 1e-13
Identities = 49/167 (29%), Positives = 84/167 (49%), Gaps = 26/167 (15%)
Query: 148 LVTLYYLNYITKFIEFIDTIFLVLKHK--KLTFLHTYHHGATALLCFTQLV--GTTAISW 203
+ TLY +N KF++ ++TIF VL+ K +++FLH +HH A A + G +++
Sbjct: 99 ICTLYLVN---KFVDLVETIFFVLRKKDRQISFLHVFHHFAMAFFGYLYYCFHGYGGVAF 155
Query: 204 VPISLNLGVHVVMYWYYFLAARGIRV----WWKEWVTRFQIIQFVVDICFIYFAVWQKVA 259
LN VHV+MY YY+L++ V WWK+++T Q++QF + + + Q
Sbjct: 156 PQCLLNTAVHVIMYAYYYLSSISKEVQRSLWWKKYITIAQLVQFAIILLHCTITLAQP-- 213
Query: 260 TDYFPSLPHCGSCVGSTTATFSGCAIISSYL-FLFIAFYIEVYRRQG 305
+C + T+ GC +S++ +F FY Y + G
Sbjct: 214 -----------NCAVNRPLTY-GCGSLSAFFAVIFSQFYYHNYIKPG 248
>7300933 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 272
Score = 74.7 bits (182), Expect = 2e-13
Identities = 41/103 (39%), Positives = 65/103 (62%), Gaps = 10/103 (9%)
Query: 150 TLY--YLNYITKFIEFIDTIFLVL--KHKKLTFLHTYHHGAT--ALLCFTQLVGTTAISW 203
TLY Y Y+ K+++ +DT+F+VL K+ +++FLH YHHG + F +G + S
Sbjct: 111 TLYASYAYYMLKYLDLLDTVFIVLRKKNSQVSFLHVYHHGGMVFGVSIFMTFLGGSHCSM 170
Query: 204 VPISLNLGVHVVMYWYYFLAARGI---RVWWKEWVTRFQIIQF 243
+ I +NL VH VMY YY+ A+ G +WWK+ +T+ Q++QF
Sbjct: 171 LGI-INLLVHTVMYAYYYAASLGAVKNLLWWKQRITQLQLMQF 212
>7299266 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 262
Score = 74.7 bits (182), Expect = 2e-13
Identities = 50/166 (30%), Positives = 85/166 (51%), Gaps = 29/166 (17%)
Query: 150 TLYYLNYITKFIEFIDTIFLVL--KHKKLTFLHTYHHGATALLCFT-----QLVGTTAIS 202
TL Y+ ++ K ++ +DTIF VL K +++TFLH +HH + FT + G
Sbjct: 103 TLSYMYHLNKVLDLMDTIFFVLRKKQRQITFLHVFHH---VFMVFTSHMLIRFYGFGGHV 159
Query: 203 WVPISLNLGVHVVMYWYYFLAARGIRV----WWKEWVTRFQIIQFVVDICFIYFAVWQKV 258
++ N+ VH+VMY YY+ +++ V WWK+++T Q++QF++ + +Q
Sbjct: 160 FLICMFNVLVHIVMYGYYYASSQSQNVQESLWWKKYLTLGQLVQFLLMFLHCMYTYFQ-- 217
Query: 259 ATDYFPSLPHCGSCVGSTTATFSGCAIISSYLFL-FIAFYIEVYRR 303
P+C + G S S+++FL F FYI+ Y R
Sbjct: 218 --------PNCSASRGVIYVISSA----SAFMFLMFTKFYIKTYIR 251
>7300879 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 262
Score = 74.3 bits (181), Expect = 2e-13
Identities = 43/103 (41%), Positives = 60/103 (57%), Gaps = 11/103 (10%)
Query: 148 LVTLYYLNYITKFIEFIDTIFLVLKHK--KLTFLHTYHHGATAL---LCFTQLVGTTAIS 202
++ L YL Y++K EF DT+F VL+ K ++T+LH YHH T L + L G A
Sbjct: 143 MLNLCYLYYLSKLTEFADTMFFVLRKKSSQITWLHVYHHSVTPLETWVLVKFLAGGNAT- 201
Query: 203 WVPISLNLGVHVVMYWYYFLAARGIR----VWWKEWVTRFQII 241
P LN VHV MY+YY +AA G +WWK+++T QI+
Sbjct: 202 -FPNLLNNFVHVCMYFYYMMAAMGPEYAKFLWWKKYMTELQIV 243
>7299264 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 265
Score = 74.3 bits (181), Expect = 2e-13
Identities = 48/167 (28%), Positives = 84/167 (49%), Gaps = 28/167 (16%)
Query: 151 LYYLNYITKFIEFIDTIFLVLKHK--KLTFLHTYHH-----GATALLCFTQLVGTTAISW 203
L Y + KF++ ++T+F VL+ K +++FLH +HH G + F GT
Sbjct: 107 LTYSYFFNKFMDLLETVFFVLRKKDRQISFLHVFHHLVMSFGGYLHITFNGYGGTL---- 162
Query: 204 VPISL-NLGVHVVMYWYYFLAARGIRVW---WKEWVTRFQIIQFVVDICFIYFAVWQKVA 259
P+ L N+ VHV+MY YY+L++ V WK+++T Q++QF++ + + + Q
Sbjct: 163 FPLCLLNVAVHVIMYAYYYLSSVSKDVQTSRWKKYITIVQLVQFILVLANFSYTLMQP-- 220
Query: 260 TDYFPSLPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVYRRQGT 306
C S T ++G I ++++ +F FYI Y G+
Sbjct: 221 -----------DCNASRTVIYTGMFISTTFILMFANFYIHNYILNGS 256
>Hs11464975 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 299
Score = 73.9 bits (180), Expect = 3e-13
Identities = 63/264 (23%), Positives = 109/264 (40%), Gaps = 47/264 (17%)
Query: 61 VSGELPLSELYPVLAAIATYYLVIFGGRAVLKNSEPFKXXXXXXXXXXXXXXXXXXXXXX 120
V G L P Y L+++ G ++N +PF
Sbjct: 23 VKGWFLLDNYIPTFICSVIYLLIVWLGPKYMRNKQPFSCRGILVVYNLGLTLLSLYMFCE 82
Query: 121 MIEQLTPMIIRHGLYYAICN----YGAWTQPLVTLYYLNYITKFIEFIDTIFLVLK--HK 174
++ + G Y C G ++ + + Y +K IEF+DT F +L+ +
Sbjct: 83 LVTG-----VWEGKYNFFCQGTRTAGESDMKIIRVLWWYYFSKLIEFMDTFFFILRKNNH 137
Query: 175 KLTFLHTYHHGATALLCFTQLVGTTAISWVPI-------SLNLGVHVVMYWYYFLAA-RG 226
++T LH YHH + + + ++WVP +LN +HV+MY YY L++
Sbjct: 138 QITVLHVYHHASMLNIWWF------VMNWVPCGHSYFGATLNSFIHVLMYSYYGLSSVPS 191
Query: 227 IR--VWWKEWVTRFQIIQFVVDICFIYFAVWQKVATDYFPSLPHCG---SCVGSTTATFS 281
+R +WWK+++T+ Q++QFV+ I + T CG C +
Sbjct: 192 MRPYLWWKKYITQGQLLQFVLTI----------IQTS-------CGVIWPCTFPLGWLYF 234
Query: 282 GCAIISSYLFLFIAFYIEVYRRQG 305
+ S + LF FYI+ Y ++G
Sbjct: 235 QIGYMISLIALFTNFYIQTYNKKG 258
>7300874 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 277
Score = 73.6 bits (179), Expect = 4e-13
Identities = 48/159 (30%), Positives = 80/159 (50%), Gaps = 20/159 (12%)
Query: 153 YLNYITKFIEFIDTIFLVL--KHKKLTFLHTYHHGATALLCFTQLVGTTAISWVPIS-LN 209
+L YI K E +DT+F VL K ++++FLH YHH + F + + +N
Sbjct: 120 WLYYIAKITELLDTVFFVLRKKQRQISFLHLYHHTLMPVCAFIGVKYFAGGHGTLLGFIN 179
Query: 210 LGVHVVMYWYYFLAARGIRV----WWKEWVTRFQIIQFVVDICFIYFAVWQKVATDYFPS 265
+H++MY YY L+A G +V WWK+++T QI+QF+ I F++ Q FP
Sbjct: 180 SFIHIIMYAYYLLSAMGPKVQKYLWWKKYITILQIVQFL--IIFVHTLQIQFQPNCNFPK 237
Query: 266 LPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVYRRQ 304
+ TF+ + ++F AFY+ Y+++
Sbjct: 238 SI-------AALLTFNA----GLFTYMFSAFYVANYKKE 265
>7296847 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 245
Score = 73.6 bits (179), Expect = 4e-13
Identities = 40/104 (38%), Positives = 61/104 (58%), Gaps = 7/104 (6%)
Query: 148 LVTLYYLNYITKFIEFIDTIFLVL--KHKKLTFLHTYHHGATALLCFTQL-VGTTAISWV 204
+V + + YI+KF EF DT+F +L K++ ++ LH HHG + L S
Sbjct: 3 MVNICWWYYISKFTEFFDTLFFILRKKNEHVSTLHVIHHGCMPFSVWMGLKFAPGGHSTF 62
Query: 205 PISLNLGVHVVMYWYYFLAARGIR----VWWKEWVTRFQIIQFV 244
LN VH+VMY+YY +AA G + +WWK+++T FQ++QFV
Sbjct: 63 FALLNSFVHIVMYFYYMIAAMGPKYQKYIWWKKYLTTFQMVQFV 106
>7302565 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 221
Score = 73.2 bits (178), Expect = 6e-13
Identities = 52/158 (32%), Positives = 85/158 (52%), Gaps = 26/158 (16%)
Query: 157 ITKFIEFIDTIFLVLK--HKKLTFLHTYHH-----GATALLCFTQLVGTTAISWVPISLN 209
+ K ++ +DT+F VL+ +K++TFLH YHH G+ AL T+ GT LN
Sbjct: 68 LNKVLDLMDTVFFVLRKSYKQITFLHIYHHVFMSFGSYAL---TRYYGTGGHVNAVGLLN 124
Query: 210 LGVHVVMYWYYFLAAR--GIR--VWWKEWVTRFQIIQFVVDICFIYFAVWQKVATDYFPS 265
VH VMY+YYFL++ G+R +WWK+++T Q+ QF + + +A++ + +
Sbjct: 125 SLVHTVMYFYYFLSSEYPGVRANIWWKKYITLTQLCQFFM---LLSYAIYVRFFS----- 176
Query: 266 LPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVYRR 303
P+CG G + +++LF FYI+ Y R
Sbjct: 177 -PNCGVPRGLLYLNMVQGVV---FIYLFGKFYIDNYLR 210
>7299268 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 264
Score = 70.9 bits (172), Expect = 3e-12
Identities = 61/249 (24%), Positives = 101/249 (40%), Gaps = 37/249 (14%)
Query: 72 PVLAAIATY-YLVIFGGRAVLKNSEPFKXXXXXXXXXXXXXXXXXXXXXXMIEQLTPMII 130
PVL +ATY + V G +++N +PF + ++
Sbjct: 27 PVLMVLATYLFFVKIAGPKIMRNRKPFDLRGLIKAYNIMQIVYNVIMCFFAVH----FML 82
Query: 131 RHGLYYAIC--------NYGAWTQPLVTLYYLNYITKFIEFIDTIFLVLKHK--KLTFLH 180
G Y C Y W + L Y+ N K ++ ++T+F VL+ K +++FLH
Sbjct: 83 GPGDYNFKCIKNLPPDHEYKTWERWLTYSYFFN---KLLDLLETVFFVLRKKDRQISFLH 139
Query: 181 TYHHGATALLCFTQLV--GTTAISWVPISLNLGVHVVMYWYYFLAARGIR----VWWKEW 234
+HH F L G + N+ VH++MY YY+ ++ +WWK++
Sbjct: 140 VFHHMYMLYFSFMYLYYYGYGGHGFFMCFFNVVVHIMMYSYYYQSSLNRDSKGDLWWKKY 199
Query: 235 VTRFQIIQFVVDICFIYFAVWQKVATDYFPSLPHCGSCVGSTTATFSGCAIISSYLFLFI 294
+T Q+IQF + + + + Q PS +C GS + F + LF
Sbjct: 200 ITIVQLIQFGIVLGHSIYTLKQPDC----PSARFSATCAGSISVVF---------IILFS 246
Query: 295 AFYIEVYRR 303
FY Y R
Sbjct: 247 NFYFHAYIR 255
>7294075 [I] KOG3072 Long chain fatty acid elongase
Length = 313
Score = 70.9 bits (172), Expect = 3e-12
Identities = 67/232 (28%), Positives = 100/232 (42%), Gaps = 15/232 (6%)
Query: 80 YYLVIFGGRAVLKNSEPFKXXXXXXXXXXXXXXXXXXXXXXMIEQLTPMIIRHGLYYAIC 139
Y LVIFGG+ ++N F+ +L ++ +GL++++C
Sbjct: 42 YMLVIFGGQHFMQNRPRFQLRGPLIIWNTLLAMFSIMGAARTAPELIHVLRHYGLFHSVC 101
Query: 140 NYGAWTQPLVTLYY--LNYITKFIEFIDTIFLVLKHKKLTFLHTYHHGATALL--CFTQL 195
Q V ++ L ++K E DTIF+VL+ + L FLH YHH T L+ F+
Sbjct: 102 VPSYIEQDRVCGFWTWLFVLSKLPELGDTIFIVLRKQPLIFLHWYHH-ITVLIYSWFSYT 160
Query: 196 VGTTAISWVPISLNLGVHVVMYWYYFLAARGIRV--WWKEWVTRFQIIQFVVDICFIYFA 253
T++ W I +N VH VMY YY L A + +T Q+ Q ++ C I
Sbjct: 161 EYTSSARWF-IVMNYCVHSVMYSYYALKAARFNPPRFISMIITSLQLAQMIIG-CAI--N 216
Query: 254 VWQKVATDYFPSLPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVYRRQG 305
VW + F SC S A+ SSY LF F+ + Y G
Sbjct: 217 VW----ANGFLKTHGTSSCHISQRNINLSIAMYSSYFVLFARFFYKAYLAPG 264
>CE10284 [I] KOG3072 Long chain fatty acid elongase
Length = 286
Score = 69.7 bits (169), Expect = 6e-12
Identities = 47/158 (29%), Positives = 80/158 (49%), Gaps = 15/158 (9%)
Query: 153 YLNYITKFIEFIDTIFLVLKHKKLTFLHTYHHGAT---ALLCFTQLVGTTAISWVPISLN 209
+L I+K E +DT+F+VL+ + L F+H YHH T AL+C+ + + WV + +N
Sbjct: 120 FLWVISKIPELLDTVFIVLRKRPLIFMHWYHHALTGYYALVCYHE--DAVHMVWV-VWMN 176
Query: 210 LGVHVVMYWYYFLAARGIRV--WWKEWVTRFQIIQFVVDICFIYFAVWQKVATDYFPSLP 267
+H MY YY L + + + + +T Q++QF V A++ +V Y +
Sbjct: 177 YIIHAFMYGYYLLKSLKVPIPPSVAQAITTSQMVQFAV-------AIFAQVHVSYKHYVE 229
Query: 268 HCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVYRRQG 305
S T G ++++Y +L+I FY E Y + G
Sbjct: 230 GVEGLAYSFRGTAIGFFMLTTYFYLWIQFYKEHYLKNG 267
>CE00112 [I] KOG3072 Long chain fatty acid elongase
Length = 291
Score = 69.7 bits (169), Expect = 6e-12
Identities = 49/171 (28%), Positives = 75/171 (43%), Gaps = 10/171 (5%)
Query: 133 GLYYAICNYGAWTQPLVTLYYLNYITKFIEFIDTIFLVLKHKKLTFLHTYHHGATALLCF 192
G Y +C T + ++K +E DT+F++L+ + L FLH YHH A +
Sbjct: 115 GFYKTLCYSCNPTDVAAFWSFAFALSKIVELGDTMFIILRKRPLIFLHYYHHAAVLIYTV 174
Query: 193 TQLVGTTAISWVPISLNLGVHVVMYWYYFLAARGIRV--WWKEWVTRFQIIQFVVDICFI 250
TA I +N H +MY YY ++A G R+ W VT Q Q + +
Sbjct: 175 HSGAEHTAAGRFYILMNYFAHSLMYTYYTVSAMGYRLPKWVSMTVTTVQTTQMLAGVGIT 234
Query: 251 YFAVWQKVATDYFPSLPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVY 301
+ KV T+Y LP C S + I ++ LFI F+++ Y
Sbjct: 235 WMV--YKVKTEY--KLP----CQQSVANLYLAFVIYVTFAILFIQFFVKAY 277
>7302564 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 262
Score = 68.2 bits (165), Expect = 2e-11
Identities = 44/116 (37%), Positives = 59/116 (49%), Gaps = 14/116 (12%)
Query: 151 LYYLNYITKFIEFIDTIFLVLK--HKKLTFLHTYHH-----GATALLCFTQLVGTTAISW 203
L Y +I K I+ IDTIF VL+ +K++T LH YHH G F G +
Sbjct: 108 LTYFYFINKVIDLIDTIFFVLRKSNKQITVLHVYHHVFMVLGVPLTYYFYGPGGQYNLMG 167
Query: 204 VPISLNLGVHVVMYWYYFLAARGIRV----WWKEWVTRFQIIQFVVDICFIYFAVW 255
LN VHVVMY YYF +A V WWKE++T+ Q +QF++ +W
Sbjct: 168 Y---LNSFVHVVMYAYYFASAWYPNVKSTFWWKEYITKLQFLQFMILFAQSVLTLW 220
>7299267 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 261
Score = 67.8 bits (164), Expect = 2e-11
Identities = 45/169 (26%), Positives = 81/169 (47%), Gaps = 24/169 (14%)
Query: 141 YGAWTQPLVTLYYLNYITKFIEFIDTIFLVL--KHKKLTFLHTYHHGATALLCFTQLV-- 196
Y W + L Y+ N K ++ ++T+F + K+++++FLH +HH + F +
Sbjct: 97 YKNWERWLSYSYFFN---KLMDLLETVFFIFRKKYRQISFLHVFHHVYMVYIGFLYMYYY 153
Query: 197 GTTAISWVPISLNLGVHVVMYWYYFLAA----RGIRVWWKEWVTRFQIIQFVVDICFIYF 252
G + I+ N+ VH +MY YY+ ++ G +WWK+++T Q++QFV+ +
Sbjct: 154 GYGGHGFFLITFNVVVHTMMYTYYYQSSLNRNSGGDLWWKKYITVVQLVQFVIIFSHSVY 213
Query: 253 AVWQKVATDYFPSLPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVY 301
+ Q TD C S + G I ++ LF FY+ Y
Sbjct: 214 ILRQ---TD----------CQTSRLSATWGSLISVVFIILFSNFYVRTY 249
>7298969 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 276
Score = 65.5 bits (158), Expect = 1e-10
Identities = 53/162 (32%), Positives = 78/162 (47%), Gaps = 29/162 (17%)
Query: 156 YITKFIEFIDTIFLVLKHK--KLTFLHTYHHGATAL-----LCFTQLVGTTAISWVPISL 208
Y +KF EF DT F V++ + +++ LH HHG + + FT +T + L
Sbjct: 66 YFSKFTEFFDTFFFVMRKRYDQVSTLHVIHHGIMPVSVWWGVKFTPGGHSTFFGF----L 121
Query: 209 NLGVHVVMYWYYFLAARGIRV----WWKEWVTRFQIIQFVVDICFIYFAVWQKVATDYFP 264
N VH+ MY YY LAA G +V WWK+++T Q+IQFV+ + + ++
Sbjct: 122 NTFVHIFMYAYYMLAAMGPKVQKYLWWKKYLTVMQMIQFVLVMVHSFQLFFKN------- 174
Query: 265 SLPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVY-RRQG 305
C +G A F G + Y FLF FY Y +R G
Sbjct: 175 ---DCNYPIG--FAYFIGAHAVMFY-FLFSNFYKRAYVKRDG 210
>Hs13489093 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 279
Score = 63.9 bits (154), Expect = 3e-10
Identities = 36/105 (34%), Positives = 59/105 (55%), Gaps = 7/105 (6%)
Query: 148 LVTLYYLNYITKFIEFIDTIFLVLKHK--KLTFLHTYHHGATALLCFTQL-VGTTAISWV 204
+V + +L +KFIE +DT+ +L+ K ++TFLH +HH + + + +
Sbjct: 107 MVRVAWLFLFSKFIELMDTVIFILRKKDGQVTFLHVFHHSVLPWSWWWGVKIAPGGMGSF 166
Query: 205 PISLNLGVHVVMYWYYFLAARGI----RVWWKEWVTRFQIIQFVV 245
+N VHV+MY YY L+A G +WWK+ +T Q+IQFV+
Sbjct: 167 HAMINSSVHVIMYLYYGLSAFGPVAQPYLWWKKHMTAIQLIQFVL 211
>CE22388 [I] KOG3072 Long chain fatty acid elongase
Length = 286
Score = 62.4 bits (150), Expect = 1e-09
Identities = 47/175 (26%), Positives = 78/175 (43%), Gaps = 11/175 (6%)
Query: 129 IIRHGLYYAICNYGAWTQPLVTLYYLNYITKFIEFIDTIFLVLKHKKLTFLHTYHHGATA 188
+ R G +IC P + ++K EF DT+FLVL+ + + FLH YHH
Sbjct: 108 VFRRGFIDSICLAVNPRSPSAFWACMFALSKIAEFGDTMFLVLRKRPVIFLHWYHHAVVL 167
Query: 189 LLCFTQLVGTTAISWVPISLNLGVHVVMYWYYFLAARGIRV--WWKEWVTRFQIIQFVVD 246
+L + + TA I +N VH +MY YY + + G R+ VT Q +Q ++
Sbjct: 168 ILSWHAAIELTAPGRWFIFMNYLVHSIMYTYYAITSIGYRLPKIVSMTVTFLQTLQMLIG 227
Query: 247 ICFIYFAVWQKVATDYFPSLPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVY 301
+ ++ K+ + C + +F I +S+L LF +F+ Y
Sbjct: 228 VSISCIVLYLKLNGEM------CQQSYDNLALSF---GIYASFLVLFSSFFNNAY 273
>Hs17454617 [I] KOG3072 Long chain fatty acid elongase
Length = 270
Score = 61.6 bits (148), Expect = 2e-09
Identities = 62/258 (24%), Positives = 100/258 (38%), Gaps = 19/258 (7%)
Query: 53 FIPSQFKFVSGELPLSELYPVLA-AIATYYLVIFG-GRAVLKNSEPFKXXXXXXXXXXXX 110
F P F+ P E Y + IA YLV+ G+ +K + F
Sbjct: 15 FQPYNFELSKDMRPFFEEYWATSFPIALIYLVLIAVGQNYMKERKGFNLQGPLILWSFCL 74
Query: 111 XXXXXXXXXXMIEQLTPMIIRHGLYYAICNYGAWTQPLVTLY-YLNYITKFIEFIDTIFL 169
M + +++ GL +C V + ++ ++K IE DT F+
Sbjct: 75 AIFSILGAVRMWGIMGTVLLTGGLKQTVCFINFIDNSTVKFWSWVFLLSKVIELGDTAFI 134
Query: 170 VLKHKKLTFLHTYHHGATAL-LCFTQLVGTTAISWVPISLNLGVHVVMYWYYFLAARGIR 228
+L+ + L F+H YHH + F A W +++N GVH +MY YY L A ++
Sbjct: 135 ILRKRPLIFIHWYHHSTVLVYTSFGYKNKVPAGGWF-VTMNFGVHAIMYTYYTLKAANVK 193
Query: 229 --VWWKEWVTRFQIIQ-FVVDICFIYFAVWQKVATDYFPSLPHCGSCVGSTTATFSGCAI 285
+T QI+Q FV I I +W++ C + F +
Sbjct: 194 PPKMLPMLITSLQILQMFVGAIVSILTYIWRQDQ-----------GCHTTMEHLFWSFIL 242
Query: 286 ISSYLFLFIAFYIEVYRR 303
+Y LF F+ + Y R
Sbjct: 243 YMTYFILFAHFFCQTYIR 260
>CE04292 [I] KOG3072 Long chain fatty acid elongase
Length = 435
Score = 60.5 bits (145), Expect = 4e-09
Identities = 50/176 (28%), Positives = 74/176 (41%), Gaps = 27/176 (15%)
Query: 136 YAICNY-------GAWTQPLVTLYYLNYITKFIEFIDTIFLVLKHKKLTFLHTYHHGATA 188
Y+IC+ G WT+ ++K E IDTIF+VL+ + L FLH YHH
Sbjct: 142 YSICHSSYAQGVTGFWTEQFA-------MSKLFELIDTIFIVLRKRPLIFLHWYHHVTVM 194
Query: 189 LLCFTQLVGTTAISWVPISLNLGVHVVMYWYYFLAARGIRV--WWKEWVTRFQIIQFVVD 246
+ + TA I +N GVH +MY YY L + R+ VT Q+ Q V+
Sbjct: 195 IYTWHAYKDHTASGRWFIWMNYGVHALMYSYYALRSLKFRLPKQMAMVVTTLQLAQMVMG 254
Query: 247 ICFIYFAVWQKVATDYF-PSLPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVY 301
+ K + +Y + + G C G + +Y LF F+ Y
Sbjct: 255 VIIGVTVYRIKSSGEYCQQTWDNLGLCFG----------VYFTYFLLFANFFYHAY 300
>7294766 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 140
Score = 52.8 bits (125), Expect = 8e-07
Identities = 23/52 (44%), Positives = 33/52 (63%), Gaps = 8/52 (15%)
Query: 156 YITKFIEFIDTIFLVLKHK--KLTFLHTYHHGATALLCFTQLVGTTAISWVP 205
YI+K +EF+DT F +L+HK +L+FLH YHH L C+T + W+P
Sbjct: 11 YISKILEFVDTAFFILRHKWNQLSFLHVYHHSTMFLFCWTY------VKWLP 56
>HsM7705799 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 200
Score = 49.7 bits (117), Expect = 7e-06
Identities = 27/83 (32%), Positives = 46/83 (54%), Gaps = 3/83 (3%)
Query: 148 LVTLYYLNYITKFIEFIDTIFLVLKHK--KLTFLHTYHHGATALLCFTQL-VGTTAISWV 204
+V + +L +KFIE +DT+ +L+ K ++TFLH +HH + + + +
Sbjct: 107 MVRVAWLFLFSKFIELMDTVIFILRKKDGQVTFLHVFHHSVLPWSWWWGVKIAPGGMGSF 166
Query: 205 PISLNLGVHVVMYWYYFLAARGI 227
+N VHV+MY YY L+A G+
Sbjct: 167 HAMINSSVHVIMYLYYGLSAFGL 189
>Hs18561450 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 128
Score = 49.3 bits (116), Expect = 9e-06
Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 20/103 (19%)
Query: 208 LNLGVHVVMYWYYFLAARGIR----VWWKEWVTRFQIIQFVVDICFIYFAVWQKVATDYF 263
LN VHVVMY YY L+A G +WWK+++T Q++QFV+ I + + F
Sbjct: 23 LNTAVHVVMYSYYGLSALGPAYQKYLWWKKYLTSLQLVQFVIVAIHISQFFFMEDCKYQF 82
Query: 264 PSLPHCGSCVGSTTATFSGCAIISSYLFLFIAFYIEVYRRQGT 306
P II SY F+F+ ++ + R T
Sbjct: 83 PVF----------------ACIIMSYSFMFLLLFLHFWYRAYT 109
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.327 0.141 0.451
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,983,134
Number of Sequences: 60738
Number of extensions: 717918
Number of successful extensions: 2286
Number of sequences better than 1.0e-05: 40
Number of HSP's better than 0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 2187
Number of HSP's gapped (non-prelim): 45
length of query: 353
length of database: 30,389,216
effective HSP length: 107
effective length of query: 246
effective length of database: 23,890,250
effective search space: 5877001500
effective search space used: 5877001500
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)