ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0953 good LD KOG2227 Cell cycle control, cell division, chromosome partitioning Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase
r_klactIII0953 good LD KOG2227 Replication, recombination and repair Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0953 328910 330478 523
(523 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL194w [LD] KOG2227 Pre-initiation complex subunit CDC6 AAA+ su... 318 1e-86
7295060 [LD] KOG2227 Pre-initiation complex subunit CDC6 AAA+ su... 133 7e-31
SPBC14C8.07c [LD] KOG2227 Pre-initiation complex subunit CDC6 AA... 124 5e-28
At1g07270 [LD] KOG2227 Pre-initiation complex subunit CDC6 AAA+ ... 119 1e-26
At2g29680 [LD] KOG2227 Pre-initiation complex subunit CDC6 AAA+ ... 106 1e-22
Hs4502703 [LD] KOG2227 Pre-initiation complex subunit CDC6 AAA+ ... 104 3e-22
Hs4758850 [L] KOG1514 Origin recognition complex subunit 1 and r... 82 2e-15
SPBC29A10.15 [L] KOG1514 Origin recognition complex subunit 1 an... 77 8e-14
At4g12620 [L] KOG1514 Origin recognition complex subunit 1 and r... 74 4e-13
At4g14700 [L] KOG1514 Origin recognition complex subunit 1 and r... 74 7e-13
CE19131 [L] KOG1514 Origin recognition complex subunit 1 and rel... 73 9e-13
CE08688 [LD] KOG2227 Pre-initiation complex subunit CDC6 AAA+ su... 66 1e-10
7304200 [L] KOG1514 Origin recognition complex subunit 1 and rel... 62 3e-09
>YJL194w [LD] KOG2227 Pre-initiation complex subunit CDC6 AAA+ superfamily
ATPase
Length = 513
Score = 318 bits (815), Expect = 1e-86
Identities = 197/517 (38%), Positives = 302/517 (58%), Gaps = 59/517 (11%)
Query: 41 PASPEKKQIKKPLGIVSSNLTNINDEPYTIESDLKPKRLMFGSDPIFSKTKSLLQQSS-V 99
PA+P + +K L T++ E P++L FGS IF +TK+LLQ+SS +
Sbjct: 21 PATPPRPLKRKKL-----QFTDVTPES-------SPEKLQFGSQSIFLRTKALLQKSSEL 68
Query: 100 SNLEQT--WLATRKSEYDEIMHFFHNSISDRESADNSLYITGPPGTGKTAQLDLILRDKF 157
NL + L R +EY+++M+F +IS+ S +SLYITGPPGTGKTAQLD+I+R KF
Sbjct: 69 VNLNSSDGALPARTAEYEQVMNFLAKAISEHRS--DSLYITGPPGTGKTAQLDMIIRQKF 126
Query: 158 HEIILD---PKNKKVTKH-DPELLNTSYFETQSDIFQSIAVAKVNCIALSKPECIFQKLL 213
+ L P++K V +H +P L N S+FE +S+AV +NCI+L +P IFQK+
Sbjct: 127 QSLPLSLSTPRSKDVLRHTNPNLQNLSWFELPDGRLESVAVTSINCISLGEPSSIFQKIF 186
Query: 214 --LEIVNGKYKQQHHKACDSVKNLKSFCRS-KPNTHFIFILDEMDKLIKQTTVLSSATKI 270
+ +NG Q ++++L+ F T F+ +LDEMD+L+ T + + +
Sbjct: 187 DSFQDLNGPTLQ-----IKNMQHLQKFLEPYHKKTTFVVVLDEMDRLLHANTSETQSVRT 241
Query: 271 ILDLFLLAKEPGINVTIIGIANSIDLKDRVLNRLNLQKELLPKVIHFHPYNSEQMFEIVR 330
IL+LFLLAK P ++ +IG+ANS+D+KDR L+RLNL + LLP+ I F PY +EQM+EIV
Sbjct: 242 ILELFLLAKLPTVSFVLIGMANSLDMKDRFLSRLNLDRGLLPQTIVFQPYTAEQMYEIVI 301
Query: 331 SKLSIFPACFEIFQPMAIKFATTKCSGSTGXXXXXXXXXXSSVQLLELES---------- 380
K+S P IFQPMAIKFA KC+G+TG S+++ ELE
Sbjct: 302 QKMSSLPTI--IFQPMAIKFAAKKCAGNTGDLRKLFDVLRGSIEIYELEKRFLLSPTRGS 359
Query: 381 --------------LKGNSDKTRGRKVTITHVAKAVSKYMNSATTKTRIAPLNIQQKIIL 426
+K + + +G K+ + ++AK SK++N+ +T+TRIA LNIQQK+IL
Sbjct: 360 LNSAQVPLTPTTSPVKKSYPEPQG-KIGLNYIAKVFSKFVNNNSTRTRIAKLNIQQKLIL 418
Query: 427 CSLVHRERFDLNKCLCTVEEAYDYYVKLLKRTDVMKPLSKAEFFESCYSLQSSGVALIEF 486
C+++ + + + T++E++D+Y+K + +TD + PL + EF E C L++ G+ I+
Sbjct: 419 CTIIQSLKLNSD---ATIDESFDHYIKAITKTDTLAPLQRNEFLEICTILETCGLVSIKK 475
Query: 487 TKKKLLPSGAAKTIKSTVIGTELQEEISKIDLLKRLL 523
TK K I + E +E++KI +LK L
Sbjct: 476 TKCKGKTKRFVDKIDVDLDMREFYDEMTKISILKPFL 512
>7295060 [LD] KOG2227 Pre-initiation complex subunit CDC6 AAA+ superfamily
ATPase
Length = 662
Score = 133 bits (334), Expect = 7e-31
Identities = 120/477 (25%), Positives = 216/477 (45%), Gaps = 90/477 (18%)
Query: 40 PPASPEKKQIKKPLGIVSSNLTNINDEPYTIESDLKPKRLMFGSDPIFSKTKSLLQQSSV 99
P P K Q K+ I ++ T N+ P P R + + +L +
Sbjct: 218 PTKQPNKNQTKEKSNIQTNEETQQNNLP-------SPSRNKY------QNARRVLNSAET 264
Query: 100 SNLEQTWLATRKSEYDEIMHFFHNSISDRESADNSLYITGPPGTGKTAQLDLILRDKFHE 159
NL R+S+ E+ FF N + + S SLY++G PGTGKTA L L+LRD
Sbjct: 265 QNLPG-----RESQLQELREFFSNHLESQTSG--SLYVSGQPGTGKTACLSLLLRDP--- 314
Query: 160 IILDPKNKKVTKHDPELLNTSYFETQSDIFQSIAVAKVNCIALSKPECIFQKLLLEI--- 216
D + + +NC +++ +++KL E+
Sbjct: 315 ---------------------------DFSKRLQRVYINCTSIASVGAVYKKLCTELQLK 347
Query: 217 VNGKYKQQHHKACDSVKNLKSFCRSKPNTHFIFILDEMDKLIKQTTVLSSATKIILDLFL 276
V+G+ ++ H +A ++LK+ R + +LDE+D+L +S +++ +F
Sbjct: 348 VSGRTERDHLEAIQ--RHLKTAKRM-----LLLVLDEIDQLC------TSRQEVLYTIFE 394
Query: 277 LAKEPGINVTIIGIANSIDLKDRVLNRLNLQKELLPKVIHFHPYNSEQMFEIVRSKLSIF 336
PG + ++GIANS+DL DR L RLN + EL P+++HF PY+ +Q+ EI +S+L+
Sbjct: 395 WPALPGSRILLVGIANSLDLTDRALMRLNARCELKPRLMHFPPYSKQQIVEIFKSRLA-E 453
Query: 337 PACFEIFQPMAIKFATTKCSGSTGXXXXXXXXXXSSVQLLELESLKGNSD---------- 386
++F P+ ++ K S +G V++ E + G +
Sbjct: 454 AEVLDVFPPVTLQLLAAKVSAISGDVRRALDIGRRVVEIAEQQKRDGEKEFNMKALQLEG 513
Query: 387 ---------KTRGRKVTITHVAKAVSK-YMNSATTKTRI-APLNIQQKIILCSLVHRERF 435
+ + V +T VA ++K Y S + I A +QQK++LC+LV R
Sbjct: 514 KDAVEAKEKQDTLKPVQVTQVAAVLNKVYGASQNLEEDIEASFPLQQKLMLCTLVLMLRN 573
Query: 436 DLNKCLCTVEEAYDYYVKLLKRTDVMKPLSKAEFFESCYSLQSSGVALIEFTKKKLL 492
+ NK + ++ ++ Y ++ + +++ L +AEF + +++ G+ I K+ L
Sbjct: 574 ERNKDI-SMGRLHEVYRRVCAKRNIL-ALDQAEFTGTVDLVETRGILRIMRKKEPRL 628
>SPBC14C8.07c [LD] KOG2227 Pre-initiation complex subunit CDC6 AAA+ superfamily
ATPase
Length = 577
Score = 124 bits (310), Expect = 5e-28
Identities = 126/528 (23%), Positives = 219/528 (40%), Gaps = 93/528 (17%)
Query: 37 LTTPPASPEKKQIKKPLGIVSSNLTNINDEPYTIESDL---KPKRLMFGSDPIFSKTKSL 93
L T P +P K K+ + IV+ N P + L P R +F P T S
Sbjct: 95 LPTTPQTP--KTPKRTIQIVTPKSLNRTCNPVPFATRLLQSTPHRQLFPPTPSTPSTPSY 152
Query: 94 LQQSSVS---NLEQTWLATRKSEYDEIMHFFHNSISDRESADNSLYITGPPGTGKTAQLD 150
+ +S + + R++E + FF + +A +LY++G PGTGKT
Sbjct: 153 NSTAKLSLRKSYRSAGVVGRENEKSIVESFFRQHLD--ANAGGALYVSGAPGTGKT---- 206
Query: 151 LILRDKFHEIILDPKNKKVTKHDPELLNTSYFETQSDIFQSIAVAKVNCIALSKPECIFQ 210
++L + ++ D + + V +NC+ +++P+ IF+
Sbjct: 207 VLLHNVLDHVVSD-------------------------YPKVNVCYINCMTINEPKAIFE 241
Query: 211 KLLLEIVNGKYKQQHHKACDSVKNLKSFCRSKPNTHF---IFILDEMDKLIKQTTVLSSA 267
K+ +IV + + + L+S N + I +LDEMD LI +
Sbjct: 242 KIHSKIVKEEILENEDHHINFQCELESHFTQSANELYNPVIIVLDEMDHLIAREQ----- 296
Query: 268 TKIILDLFLLAKEPGINVTIIGIANSIDLKDRVLNRLNLQKELLPKVIHFHPYNSEQMFE 327
+++ LF P + ++GIAN++D+ DR L RL K + PK++ F PY ++++
Sbjct: 297 -QVLYTLFEWPSRPTSRLILVGIANALDMTDRFLPRLR-TKHITPKLLSFTPYTAQEIST 354
Query: 328 IVRSKLSIFPACFE------------------------------IFQPMAIKFATTKCSG 357
I++++L E P AI+ K +
Sbjct: 355 IIKARLKTAATTSEKNNPFTPIKSISEVSDDSINVVSQHADETPFIHPAAIELCARKVAA 414
Query: 358 STGXXXXXXXXXXSSVQLLELESLKGNSDKTRGR----KVTITHVAKAVSKYMNSATTKT 413
S+G +++L E E K D T + +I HV +A S SA+
Sbjct: 415 SSGDLRKALDICRHAIELAERE-WKAQHDNTLSSVDIPRASIAHVVRATSAMSQSAS--A 471
Query: 414 RIAPLNIQQKIILCSLVHRERFDLNKCLCTVEEAYDYYVKLLKRTDVMKPLSKAEFFESC 473
R+ L +QQK ILC+LV E+ L +V + ++ Y L R ++ PL+ +EF +
Sbjct: 472 RLKNLGLQQKAILCTLVVCEKTSL-----SVADVFEKYSSLCLRDRLIYPLTSSEFCDVA 526
Query: 474 YSLQSSGVALIEFTKKKLLPSGAAKTIKSTVIGTELQEEISKIDLLKR 521
SL++ +A+I K+ + I V ++ + I LKR
Sbjct: 527 NSLET--LAIIRLRTKQRNGKPQDRIISLLVPEMDVITAVGDIGTLKR 572
>At1g07270 [LD] KOG2227 Pre-initiation complex subunit CDC6 AAA+ superfamily
ATPase
Length = 507
Score = 119 bits (298), Expect = 1e-26
Identities = 105/401 (26%), Positives = 182/401 (45%), Gaps = 45/401 (11%)
Query: 110 RKSEYDEIMHFFHNSISDRESADNSLYITGPPGTGKTAQLDLILRDKFHEIILDPKNKKV 169
R+ E I F I +++ SLYI G PGTGK+ ++ +++
Sbjct: 129 REDEQIRIFEFVKGCIDQQKAG--SLYICGCPGTGKSLSMEKVVQQ-------------- 172
Query: 170 TKHDPELLNTSYFETQSDIFQSIAVAKVNCIALSKPECIFQKLLLEIVNGKYKQQHHKAC 229
+ TQ+ + + VNC +LSK IF K+L EI GK +
Sbjct: 173 ---------VGDWSTQAGL-PPVDTLSVNCTSLSKTTDIFSKILGEIKPGKNANTNSSPL 222
Query: 230 DSVKNLKSFCRSKPNTHFIFIL-DEMDKLIKQTTVLSSATKIILDLFLLAKEPGINVTII 288
++NL S + ++ + I+ DEMD LI + ++ DLF+L P +I
Sbjct: 223 QHLQNLFSQKQESSSSRMMLIIADEMDYLITKDR------GVLYDLFMLTTLPFSRCILI 276
Query: 289 GIANSIDLKDRVLNRLNLQKELLPKVIHFHPYNSEQMFEIVRSKLSIFPACFEIFQPMAI 348
G+AN+IDL DR L +L P VI F Y+ +Q+ I++ +L + + FQP A+
Sbjct: 277 GVANAIDLADRFLPKLK-SLNCKPMVITFRAYSKDQILRILQERLRVL--SYVAFQPKAL 333
Query: 349 KFATTKCSGSTGXXXXXXXXXXSSVQLLELESLKGNSDKTRG-----RKVTITHVAKAVS 403
+ K + ++G S++++LE+E+ +++G V + H+A A+S
Sbjct: 334 ELCARKVAAASGDMRKALCVCRSALEILEIETRGSTGPESQGPTPDDSVVRMDHMAAALS 393
Query: 404 KYMNSATTKTRIAPLNIQQKIILCSLVHRERFDLNKCLCTVEEAYDYYVKLLKRTDVMKP 463
K S +T I L Q+II+C+ + F +K TV E Y+++ K + ++ P
Sbjct: 394 KTFKSPVVET-IQSLPQHQQIIICAAA--KAFRGSKKDATVGELNKLYLEICK-SWMISP 449
Query: 464 LSKAEFFESCYSLQSSGVALIEFTKKKLLPSGAAKTIKSTV 504
EF C L G+ + ++ L + + +S +
Sbjct: 450 AGITEFTNMCTVLNDQGILKVGQARRDKLKRVSLRVDESDI 490
>At2g29680 [LD] KOG2227 Pre-initiation complex subunit CDC6 AAA+ superfamily
ATPase
Length = 535
Score = 106 bits (264), Expect = 1e-22
Identities = 102/404 (25%), Positives = 177/404 (43%), Gaps = 46/404 (11%)
Query: 91 KSLLQQSSVSNLEQTWLATRKSEYDEIMHFFHNSISDRESADNSLYITGPPGTGKTAQLD 150
K++ + VS T + R+ E + F + +++ SLYI G PGTGK+ ++
Sbjct: 114 KAVKEALHVSKAPST-VVCREDEQRRVFEFVKGCMEQKKAG--SLYICGCPGTGKSLSME 170
Query: 151 LILRDKFHEIILDPKNKKVTKHDPELLNTSYFETQSDIFQSIAVAKVNCIALSKPECIFQ 210
+ + + K+ H PE ++ VNC +L+K IF
Sbjct: 171 KV------RLQAEEWAKQAGLHCPETVS------------------VNCTSLTKSTDIFS 206
Query: 211 KLLLEIVNGKYKQQHHKACDSVKNLKSFCRSKPNTHFIFIL-DEMDKLIKQTTVLSSATK 269
K+L +GK ++ L S + + + + I+ DEMD LI +
Sbjct: 207 KILGNYESGKKANGSFSPLQQLQRLFSQKQQQSRSKMMLIIADEMDYLITRDR------G 260
Query: 270 IILDLFLLAKEPGINVTIIGIANSIDLKDRVLNRLNLQKELLPKVIHFHPYNSEQMFEIV 329
++ +LF+L P +IG+AN+IDL DR L +L P V+ F Y+ +Q+ I+
Sbjct: 261 VLHELFMLTTLPLSRCILIGVANAIDLADRFLPKLK-SLNCKPLVVTFRAYSKDQILRIL 319
Query: 330 RSKLSIFPACFEIFQPMAIKFATTKCSGSTGXXXXXXXXXXSSVQLLELESLKGNSDKTR 389
+ +L P F FQ A++ K S ++G S++++LE+E + +
Sbjct: 320 QERLVALP--FVAFQSNALEICARKVSAASGDMRKALCVCRSALEILEIEVRGSIDQEPK 377
Query: 390 G-----RKVTITHVAKAVSKYMNSATTKTRIAPLNIQQKIILCSLVHRERFDLNKCLCTV 444
G + V + H+ A+SK S T I L Q+II+CS + F +K T+
Sbjct: 378 GPVPECQVVKMDHMIAALSKTFKSPIVDT-IQSLPQHQQIIVCSAA--KAFRGSKKDRTI 434
Query: 445 EEAYDYYVKLLKRTDVMKPLSKAEFFESCYSLQSSGVALIEFTK 488
E Y+++ K + ++ P EF C L G+ + +
Sbjct: 435 AELNKLYLEICK-SSMITPAGITEFSNMCTVLNDQGILKLSLAR 477
>Hs4502703 [LD] KOG2227 Pre-initiation complex subunit CDC6 AAA+ superfamily
ATPase
Length = 560
Score = 104 bits (260), Expect = 3e-22
Identities = 92/400 (23%), Positives = 181/400 (45%), Gaps = 56/400 (14%)
Query: 107 LATRKSEYDEIMHFFHNSISDRESADNSLYITGPPGTGKTAQLDLILRDKFHEIILDPKN 166
L R+ E D I +F I +++ SLY++G PGTGKTA L IL+D E+
Sbjct: 172 LPAREREMDVIRNFLREHICGKKAG--SLYLSGAPGTGKTACLSRILQDLKKEL------ 223
Query: 167 KKVTKHDPELLNTSYFETQSDIFQSIAVAKVNCIALSKPECIFQKLLLEIVNGKYKQQHH 226
+ +NC++L + +F + EI + +
Sbjct: 224 -----------------------KGFKTIMLNCMSLRTAQAVFPAIAQEICQEEVSRPAG 260
Query: 227 KACDSVKNLKSFCRSKPNTHFIFILDEMDKLIKQTTVLSSATKIILDLFLLAKEPGINVT 286
K D ++ L+ ++ + +LDEMD+L S ++ LF ++
Sbjct: 261 K--DMMRKLEKHMTAEKGPMIVLVLDEMDQLD------SKGQDVLYTLFEWPWLSNSHLV 312
Query: 287 IIGIANSIDLKDRVLNRLNLQKELLPKVIHFHPYNSEQMFEIVRSKLSIFPACFEIFQPM 346
+IGIAN++DL DR+L RL +++ P++++F PY Q+ I++ +L+ + ++
Sbjct: 313 LIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQV-SRDQVLDNA 371
Query: 347 AIKFATTKCSGSTGXXXXXXXXXXSSVQLLE-----------LESLKGNSDKTRGRKVTI 395
A++F K S +G +++++E L K S+ ++V +
Sbjct: 372 AVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGL 431
Query: 396 THVAKAVSKYMNSATTKTRIAPLN---IQQKIILCSLVHRERFDLNKCLCTVEEAYDYYV 452
H+++ +S+ + T ++ + +QQKI++CSL+ R L T+ + Y+ Y
Sbjct: 432 IHISQVISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIR-QLKIKEVTLGKLYEAYS 490
Query: 453 KLLKRTDVMKPLSKAEFFESCYSLQSSGVALIEFTKKKLL 492
K+ ++ V + ++E L++ G+ ++ K+ L
Sbjct: 491 KVCRKQQV-AAVDQSECLSLSGLLEARGILGLKRNKETRL 529
>Hs4758850 [L] KOG1514 Origin recognition complex subunit 1 and related
proteins
Length = 861
Score = 82.0 bits (201), Expect = 2e-15
Identities = 109/468 (23%), Positives = 195/468 (41%), Gaps = 65/468 (13%)
Query: 38 TTPPASPEKKQIKKPLGIVSSNLTNINDEPYTIESDLKPKRLMFGSDPIFSKTKSLLQQS 97
+TPP P + + SS ++++ + LKP+ + I +++SL Q
Sbjct: 427 STPPL-PRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQI--RSRSLAAQE 483
Query: 98 SVSNLEQTWLAT-----------RKSEYDEIMHFFHNSISDRESADNSLYITGPPGTGKT 146
S LE+ L R+ E+ +I +F + + D +YI+G PGTGKT
Sbjct: 484 PASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGG--CMYISGVPGTGKT 541
Query: 147 AQLDLILRDKFHEIILDPKNKKVTKHDPELLNTSYFETQSDIFQSIAVAKVNCIALSKPE 206
A + HE+I L + FQ I +VN + L++P
Sbjct: 542 ATV--------HEVI-------------RCLQQAAQANDVPPFQYI---EVNGMKLTEPH 577
Query: 207 CIFQKLLLEIVNGKYKQQHHKACDSVKNLKSFC-RSKPNTHFIFILDEMDKLIKQTTVLS 265
++ +L ++ K H A + + K FC R P + ++DE+D L +
Sbjct: 578 QVYVHILQKLTGQKATANH--AAELL--AKQFCTRGSPQETTVLLVDELDLL------WT 627
Query: 266 SATKIILDLFLLAKEPGINVTIIGIANSIDLKDRV-LNRLNLQKELLPKVIHFHPYNSEQ 324
I+ +LF + ++ IAN++DL +R+ +NR++ + L + F PY Q
Sbjct: 628 HKQDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTR--MCFQPYTYSQ 685
Query: 325 MFEIVRSKLSIFPACFEIFQPMAIKFATTKCSGSTGXXXXXXXXXXSSVQLLELESLKGN 384
+ +I+RS+L A F+ AI+ K + +G + ++ E K +
Sbjct: 686 LQQILRSRLKHLKA----FEDDAIQLVARKVAALSGDARRCLDICRRATEICEFSQQKPD 741
Query: 385 SDKTRGRKVTITHVAKAVSKYMNSATTKTRIAPLNIQQKIILCSLVHRERFDLNKCLCTV 444
S VTI H +AV + +S+ ++Q + L R L + T
Sbjct: 742 SPGL----VTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRAILAEFRRSGLEE--ATF 795
Query: 445 EEAYDYYVKLLKRTDVMKPLSKAEFFESCYSLQSSGVALIEFTKKKLL 492
++ Y +V L + + P + +E C L S + L+E ++ LL
Sbjct: 796 QQIYSQHVALCRMEGLPYP-TMSETMAVCSHLGSCRLLLVEPSRNDLL 842
>SPBC29A10.15 [L] KOG1514 Origin recognition complex subunit 1 and related
proteins
Length = 707
Score = 76.6 bits (187), Expect = 8e-14
Identities = 104/442 (23%), Positives = 189/442 (42%), Gaps = 69/442 (15%)
Query: 6 RKRPFLAFESDGELGCGNSENMTPDAKRFS-----GLTTPPASPEKKQIKKPLGIVSSNL 60
RK P ES NS++ D + S LT P +P ++ + SSNL
Sbjct: 232 RKYPLPNVESKESSSKVNSKDENFDLQDDSESSEDNLTIQPQTPRRRHKRSRHN--SSNL 289
Query: 61 TNI---NDEPYTIESDLKPKRLM----FGSDPIFSKTKSLLQQSSVSNLEQTWLATRKSE 113
+ N ++ P R++ F P K +++L +SV + L R +E
Sbjct: 290 ASTPKRNGYKQPLQITPLPIRMLSLEEFQGSP-HRKARAMLHVASVPST----LQCRDNE 344
Query: 114 YDEIMHFFHNSISDRESADNSLYITGPPGTGKTAQLDLILRDKFHEIILDPKNKKVTKHD 173
+ I ++I + A LYI+G PGTGKTA + HE+I N + +
Sbjct: 345 FSTIFSNLESAIEEETGA--CLYISGTPGTGKTATV--------HEVIW---NLQELSRE 391
Query: 174 PELLNTSYFETQSDIFQSIAVAKVNCIALSKPECIFQKLLLEIVNGKYKQQHHKACDSVK 233
+L S+ E +N + ++ + +L E + G+ H A D +
Sbjct: 392 GQLPEFSFCE-------------INGMRVTSANQAY-SILWESLTGERVTPIH-AMDLLD 436
Query: 234 NLKSFCRSKPN-THFIFILDEMDKLIKQTTVLSSATKIILDLFLLAKEPGINVTIIGIAN 292
N F + PN + + ++DE+D+L+ K++ + F P + ++ +AN
Sbjct: 437 N--RFTHASPNRSSCVVLMDELDQLVTHN------QKVLYNFFNWPSLPHSRLIVVAVAN 488
Query: 293 SIDLKDRVLNRLNLQKELLPKVIHFHPYNSEQMFEIVRSKLSIFPACFEIFQPMAIKFAT 352
++DL +R+L+ + L + F PY Q+ I+ ++L ++F AI+FA
Sbjct: 489 TMDLPERILSN-RISSRLGLSRVPFEPYTHTQLEIIIAARLEAV-RDDDVFSSDAIRFAA 546
Query: 353 TKCSGSTGXXXXXXXXXXSSVQLLELESLKGNSDKTRGRKVTITHVAKAVSKYMNSATTK 412
K + +G + +L E + KVT + +A+S+ M ++ +
Sbjct: 547 RKVAAVSGDARRALDICRRASELAE----------NKNGKVTPGLIHQAISE-MTASPLQ 595
Query: 413 TRIAPLNIQQKIILCSLVHRER 434
+ L+ QK+ LC++V+R R
Sbjct: 596 KVLRNLSFMQKVFLCAIVNRMR 617
>At4g12620 [L] KOG1514 Origin recognition complex subunit 1 and related
proteins
Length = 813
Score = 74.3 bits (181), Expect = 4e-13
Identities = 76/330 (23%), Positives = 145/330 (43%), Gaps = 48/330 (14%)
Query: 107 LATRKSEYDEIMHFFHNSISDRESADNSLYITGPPGTGKTAQLDLILRDKFHEIILDPKN 166
L R E +EI F SISD + +YI G PGTGKT + ++ KN
Sbjct: 439 LPCRSKEMEEITSFIKGSISDDQCLGRCMYIHGVPGTGKTISVLSVM-----------KN 487
Query: 167 KKVTKHDPELLNTSYFETQSDIFQSIAVAKVNCIALSKPECIFQKLLLEIVNGKYKQQHH 226
K E + ++N + L+ PE I+ ++ E ++G ++
Sbjct: 488 LKA-------------EVEEGSVSPYCFVEINGLKLASPENIY-SVIYEALSG-HRVGWK 532
Query: 227 KACDSVKNLKSFCRSK-----PNTHFIFILDEMDKLIKQTTVLSSATKIILDLFLLAKEP 281
KA + + F K I ++DE+D L+ + ++ ++ +P
Sbjct: 533 KALQCLN--ERFAEGKRIGKEDEKPCILLIDELDLLVTRN------QSVLYNILDWPTKP 584
Query: 282 GINVTIIGIANSIDLKDRVLNRLNLQKELLPKVIHFHPYNSEQMFEIVRSKLSIFPACFE 341
+ ++GIAN++DL +++L R++ + + + + F PYN Q+ EI+ ++L+ A
Sbjct: 585 NSKLVVLGIANTMDLPEKLLPRISSRMGI--QRLCFGPYNHTQLQEIISTRLNGIDA--- 639
Query: 342 IFQPMAIKFATTKCSGSTGXXXXXXXXXXSSVQLLELESLKGNSDKTRGRKVTITHVAKA 401
F+ AI+FA+ K + +G + E+ + N++K+ ++ I +A
Sbjct: 640 -FEKTAIEFASRKVAAISGDARRALEICRRAA---EVADHRLNTNKSAKNQLVIMADVEA 695
Query: 402 VSKYMNSATTKTRIAPLNIQQKIILCSLVH 431
+ M A + ++ KI L ++VH
Sbjct: 696 AIQEMFQAPHIQVMKSVSKLSKIFLTAMVH 725
>At4g14700 [L] KOG1514 Origin recognition complex subunit 1 and related
proteins
Length = 771
Score = 73.6 bits (179), Expect = 7e-13
Identities = 74/330 (22%), Positives = 147/330 (44%), Gaps = 47/330 (14%)
Query: 107 LATRKSEYDEIMHFFHNSISDRESADNSLYITGPPGTGKTAQLDLILRDKFHEIILDPKN 166
L R E +EI F SISD + +YI G PGTGKT + ++ KN
Sbjct: 396 LPCRSKEMEEITAFIKGSISDDQCLGRCMYIHGVPGTGKTISVLSVM-----------KN 444
Query: 167 KKVTKHDPELLNTSYFETQSDIFQSIAVAKVNCIALSKPECIFQKLLLEIVNGKYKQQHH 226
K E ++ ++N + L+ PE I+ ++ E ++G ++
Sbjct: 445 LKA-------------EVEAGSVSPYCFVEINGLKLASPENIY-SVIYEGLSG-HRVGWK 489
Query: 227 KACDSVKNLKSFCRSKP-----NTHFIFILDEMDKLIKQTTVLSSATKIILDLFLLAKEP 281
KA S+ + F K I ++DE+D L+ + ++ ++ +P
Sbjct: 490 KALQSLN--ERFAEGKKIGKENEKPCILLIDELDVLVTRN------QSVLYNILDWPTKP 541
Query: 282 GINVTIIGIANSIDLKDRVLNRLNLQKELLPKVIHFHPYNSEQMFEIVRSKLSIFPACFE 341
+ ++GIAN++DL +++L R++ + + + + F PYN Q+ EI+ ++L A
Sbjct: 542 NSKLVVLGIANTMDLPEKLLPRISSRMGI--QRLCFGPYNHRQLQEIISTRLEGINA--- 596
Query: 342 IFQPMAIKFATTKCSGSTGXXXXXXXXXXSSVQLLELESLKGNSDKTRGRKVTITHVAKA 401
F+ AI+FA+ K + +G + ++ + LK ++ + + V + V A
Sbjct: 597 -FEKTAIEFASRKVAAISGDARRALEICRRAAEVADYR-LKKSNISAKSQLVIMADVEVA 654
Query: 402 VSKYMNSATTKTRIAPLNIQQKIILCSLVH 431
+ + + + + ++ +I L ++VH
Sbjct: 655 IQEMFQAPHIQV-MKSVSKLSRIFLTAMVH 683
>CE19131 [L] KOG1514 Origin recognition complex subunit 1 and related
proteins
Length = 636
Score = 73.2 bits (178), Expect = 9e-13
Identities = 77/285 (27%), Positives = 126/285 (44%), Gaps = 46/285 (16%)
Query: 84 DPIFSKTKSLLQQSS----VSNLEQTWLATRKSEYDEIMHFFHNSISDRESADNSLYITG 139
DP+ S++ S L++ + +S + + L R E EI F I + +++YI+G
Sbjct: 241 DPLDSRSASTLKELASRLHLSKVPEK-LPCRDIESREIEKFIREVIDPKRGESSAMYISG 299
Query: 140 PPGTGKTAQLDLILRDKFHEIILDPKNKKVTKHDPELLNTSYFETQSDIFQSIAVAKVNC 199
PGTGKTA + ++ K+KK K Y E + IF+ ++
Sbjct: 300 VPGTGKTATVRAVVNSM-------KKSKKCQKF-------VYVEVNAMIFKKTVFVEI-- 343
Query: 200 IALSKPECIFQKLLLEIVNGKYKQQHHK--ACDSVKNLKS-FCRSKP-NTHFIFILDEMD 255
+ E N K Q K A + + L S F R P + ++DE+D
Sbjct: 344 ----------YNGIQEEYNISKKPQRAKITATAARQELNSIFKREDPKRPPIVVLIDELD 393
Query: 256 KLIKQTTVLSSATKIILDLFLLAKEPGINVTIIGIANSIDLKDRVLNRLNLQKELLPKVI 315
L + ++ D+F P VTIIGIAN++D +R+L + N + L + +
Sbjct: 394 SLCNR------KQDVLYDIFEWTALPQSKVTIIGIANTLDFPERMLCQRNASR-LDKRRL 446
Query: 316 HFHPYNSEQMFEIVRSKLSIFPACFEIFQPMAIKFATTKCSGSTG 360
F PY EQ+ EIVR++L + P A++ K + +TG
Sbjct: 447 VFQPYQHEQIEEIVRARLQ----GSNLIDPKAVELVAKKVAMNTG 487
>CE08688 [LD] KOG2227 Pre-initiation complex subunit CDC6 AAA+ superfamily
ATPase
Length = 518
Score = 65.9 bits (159), Expect = 1e-10
Identities = 71/281 (25%), Positives = 117/281 (41%), Gaps = 61/281 (21%)
Query: 61 TNINDEPYTIESDLKPKRLMFGSDPIFSKTKSLLQQSSVSNLEQTW-------LATRKSE 113
TN+ + T + K R GS K KS + SS S+ E+ L R+ E
Sbjct: 120 TNLKSQLTTPRTPEKQSRSRSGSQGTPEK-KSRKESSSESDSEEIISTSSEGALKGRREE 178
Query: 114 YDEIMHFFHNSISDRESADNSLYITGPPGTGKTAQLDLILRDKFHEIILDPKNKKVTKHD 173
+D + + S S S+Y++G PGTGKTA +L+
Sbjct: 179 FDSLKLWIMKSKETNTSL--SIYVSGQPGTGKTATTMRVLK------------------- 217
Query: 174 PELLNTSYFETQSDIFQSIAVAKVNCIALSKPECIFQKLLLEI-VNGKYKQQHHKACDSV 232
+ +S+ VNC + + +F+ + + ++GK ++ +
Sbjct: 218 -------------SLGKSVRSCIVNCASTNTKSALFKTIFESLDLDGKPNEEIFE----- 259
Query: 233 KNLKSFCRSKPNTHFIFILDEMDKLIKQTTVLSSATKIILDLFLLAKEPGINVTIIGIAN 292
K++K F T + +LDE+D L + A F + + I+GIAN
Sbjct: 260 KHVKQF-----KTPLVLVLDEIDHLANRKNAALYAA------FQWPETLSRKIIILGIAN 308
Query: 293 SIDLKDRVLNRLNLQKELLPKVIHFHPYNSEQMFEIVRSKL 333
SIDL +R+L +L L K PK + F PY + + EI+ K+
Sbjct: 309 SIDLTERLLPKLMLAKP--PKRLVFEPYTKDDIVEILNDKM 347
>7304200 [L] KOG1514 Origin recognition complex subunit 1 and related
proteins
Length = 924
Score = 61.6 bits (148), Expect = 3e-09
Identities = 82/393 (20%), Positives = 163/393 (40%), Gaps = 78/393 (19%)
Query: 24 SENMTPDAKRFSGLTTPPASPEKKQIKKPLGIVSSNLTNINDEPYTIESDLKPKRLMFGS 83
++ T +K + T P +P +K K G +S ++ D P
Sbjct: 500 TKTATTPSKGITTATATPMTPSQKMKKIRAGELSPSMQQRTDLP--------------AK 545
Query: 84 DPIFSKTKSLLQQSSVSNLEQTWLATRKSEYDEIMHFFHNSISDRESADNSLYITGPPGT 143
D S+ + +Q VS + ++ L R+ E++ I F I D+ +Y++G PGT
Sbjct: 546 DSSKSELQLAREQLHVSVVPKS-LPCREREFENIYAFLEGKIQDQ--CGGCMYVSGVPGT 602
Query: 144 GKTAQLDLILRDKFHEIILDPKNKKVTKHDPELLNTSYFETQSDIFQSIAVAKVNCIALS 203
GKTA + ++R +++ K + EL Y E +N + L+
Sbjct: 603 GKTATVTGVIRTL----------QRMAKQN-ELPAFEYLE-------------INGMRLT 638
Query: 204 KPECIFQKLLLEIVNGKYK-QQHHKACDSVKNLKSFCRSKP-NTHFIFILDEMDKLIKQT 261
+P + ++ ++ +Q H + K F P + ++DE+D L +
Sbjct: 639 EPRQAYVQIYKQLTGKTVSWEQAHALLE-----KRFTTPAPRRVTTVLLVDELDILCNR- 692
Query: 262 TVLSSATKIILDLFLLAKEPGINVTIIGIANSIDLKDRVL-----NRLNLQKELLPKVIH 316
++ +L + + ++ IAN++DL +R+L +RL L + +
Sbjct: 693 -----RQDVVYNLLDWPTKSAAKLVVVTIANTMDLPERLLMGKVTSRLGLTR------LT 741
Query: 317 FHPYNSEQMFEIVRSKLSIFPACFEIFQPMAIKFATTKCSGSTGXXXXXXXXXXSSVQLL 376
F PY+ +Q+ EIV ++L E F+ A++ K + +G + ++
Sbjct: 742 FQPYSHKQLQEIVTARL----GGSETFKGEAVQLVARKVAAVSGDARRALDICRRATEIA 797
Query: 377 ELESLKGNSDKTRGRKVTITHVAKAVSKYMNSA 409
+ ++K VT+ HV +A+++ + SA
Sbjct: 798 DTAAVK---------CVTMLHVQQALAEMIASA 821
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.134 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,652,223
Number of Sequences: 60738
Number of extensions: 1227952
Number of successful extensions: 4213
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 4175
Number of HSP's gapped (non-prelim): 17
length of query: 523
length of database: 30,389,216
effective HSP length: 111
effective length of query: 412
effective length of database: 23,647,298
effective search space: 9742686776
effective search space used: 9742686776
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)