ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0959 good H KOG1270 Coenzyme transport and metabolism Methyltransferases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0959 332733 331753 -327
(327 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL096c [H] KOG1270 Methyltransferases 373 e-103
SPCC162.05 [H] KOG1270 Methyltransferases 157 2e-38
At2g30920 [H] KOG1270 Methyltransferases 123 3e-28
Hs14754031 [H] KOG1270 Methyltransferases 117 2e-26
Hs8393177 [H] KOG1270 Methyltransferases 115 9e-26
7298756 [H] KOG1270 Methyltransferases 103 4e-22
CE14946 [H] KOG1270 Methyltransferases 81 2e-15
>YOL096c [H] KOG1270 Methyltransferases
Length = 316
Score = 373 bits (958), Expect = e-103
Identities = 174/286 (60%), Positives = 220/286 (76%), Gaps = 2/286 (0%)
Query: 44 TFDKSSGTSTSDDEIFHFQQLAPTWWDTWGSQRILHKMNLARLDFLQRTVRNQIKIKNDD 103
T + T S+DE+ HFQ+LAPTWWDT GSQRILHKMNL RLDF+QRTVRNQ+KI+N +
Sbjct: 31 TQTRCKSTDASEDEVKHFQELAPTWWDTDGSQRILHKMNLTRLDFVQRTVRNQVKIQNPE 90
Query: 104 VYIPGFNHHDHLPGYVTKAIDQDIFNEVQRGLGEK-KFDALDIGCGGGILSESFARLPFI 162
+++PGFN+ + LP YV I +++ ++ L ++ + LD+GCGGGILSES ARL ++
Sbjct: 91 IFVPGFNYKEFLPEYVCDNIQREMQESIETNLDKRPEVSVLDVGCGGGILSESLARLKWV 150
Query: 163 QSVTAIDLTPECIEVAKAHAAKDPSIKDKIFYKFLPLEKVHGHYDIVTMFEMLEHVDEPS 222
++V IDLT +CI VAK HA KDP ++ KI Y+ LE V G +DI+T EMLEHVD PS
Sbjct: 151 KNVQGIDLTRDCIMVAKEHAKKDPMLEGKINYECKALEDVTGQFDIITCMEMLEHVDMPS 210
Query: 223 EILRQAWSKLKPN-GVIFLSTINRDPISWFTTIFMGEQILKVVPKGTHHVEKYINSSEIK 281
EILR WS+L P G++FLSTINRD ISWFTTIFMGE +LK+VPKGTHH+ KYINS EI
Sbjct: 211 EILRHCWSRLNPEKGILFLSTINRDLISWFTTIFMGENVLKIVPKGTHHLSKYINSKEIL 270
Query: 282 QWFEDNVQGRYEILDTKGTMYLPLTGWVEHDCTNIGNYFMAIKKLN 327
WF DN G++ +LD KGTMYLP GWVEHDC+++GNYFMAI++LN
Sbjct: 271 AWFNDNYSGQFRLLDLKGTMYLPYQGWVEHDCSDVGNYFMAIQRLN 316
>SPCC162.05 [H] KOG1270 Methyltransferases
Length = 271
Score = 157 bits (398), Expect = 2e-38
Identities = 103/282 (36%), Positives = 147/282 (51%), Gaps = 51/282 (18%)
Query: 52 STSDDEIFHFQQLAPTWWDTWGSQRILHKMNLARLDFLQRTVRNQIKIKNDDVYIPGFNH 111
S S +E+ HF +LA TWWD G R+LH MN RLDF+
Sbjct: 29 SVSVNEVDHFNELAKTWWDWDGGSRLLHLMNSTRLDFMT--------------------- 67
Query: 112 HDHLPGYVTKAIDQDIFNEVQRGLGEKKFDALDIGCGGGILSESFARLPFIQSVTAIDLT 171
++F E G+K LDIGCGGGILSES ARL SVTA+D +
Sbjct: 68 --------------EVFRERNCFSGKK---ILDIGCGGGILSESMARLG--ASVTAVDAS 108
Query: 172 PECIEVAKAHAAKDPSIKDKIFYKFLPLE--KVHGHYDIVTMFEMLEHVDEPSEILRQAW 229
P IEVAK HA+ DP + ++ Y +E ++ +D+VT E+LEHV++P + L
Sbjct: 109 PMAIEVAKKHASLDPVLNGRLEYIHGSVEGSQLPTTFDVVTCMEVLEHVEQPRDFLFSLM 168
Query: 230 SKLKPNGVIFLSTINRDPISWFTTIFMGEQILKVVPKGTHHVEKYINSSEIKQWFEDNVQ 289
K+KPNG + LSTI+R ++ TI + E +L++VP GTH EK+I + E+ + ++
Sbjct: 169 EKVKPNGRLVLSTISRTLLARLLTITLAEHVLRIVPVGTHTFEKFIRADELSNFLKEQ-- 226
Query: 290 GRYEILDTKGTMYLPL-TGWVEHDCTNIG-----NYFMAIKK 325
+ I D +G Y PL W + G NYF++ +K
Sbjct: 227 -NWIINDIRGVCYNPLKQQWTLDKPGSSGLGLSCNYFLSAQK 267
>At2g30920 [H] KOG1270 Methyltransferases
Length = 322
Score = 123 bits (309), Expect = 3e-28
Identities = 92/305 (30%), Positives = 143/305 (46%), Gaps = 53/305 (17%)
Query: 28 SSSSSNDAHPK------PTHNPTFDKSSGTSTSDDEIFHFQQLAPTWWDTWGSQRILHKM 81
S++S + +HPK N + SS TS ++DE+ F +A TWW + G + LH+M
Sbjct: 45 SAASFSSSHPKIQTLEGKASNKSRSTSSTTSLNEDELAKFSAIADTWWHSEGPFKPLHQM 104
Query: 82 NLARLDFLQRTVRNQIKIKNDDVYIPGFNHHDHLPGYVTKAIDQDIFNEVQRGLGEKKFD 141
N RL F++ T+ H P K F+
Sbjct: 105 NPTRLAFIRSTL---------------CRHFSKDPS------------------SAKPFE 131
Query: 142 AL---DIGCGGGILSESFARLPFIQSVTAIDLTPECIEVAKAHAAKDPSIKDKIFYKFLP 198
L DIGCGGG+LSE AR+ +VT +D + +++A+ HA DP + I Y
Sbjct: 132 GLKFIDIGCGGGLLSEPLARMG--ATVTGVDAVDKNVKIARLHADMDP-VTSTIEYLCTT 188
Query: 199 LEKVHGH---YDIVTMFEMLEHVDEPSEILRQAWSKLKPNGVIFLSTINRDPISWFTTIF 255
EK+ +D V E++EHV P+E + + PNG LSTINR ++ +TI
Sbjct: 189 AEKLADEGRKFDAVLSLEVIEHVANPAEFCKSLSALTIPNGATVLSTINRTMRAYASTIV 248
Query: 256 MGEQILKVVPKGTHHVEKYINSSEIKQWFEDNVQGRYEILDTKGTMYLPLTG-WVEHDCT 314
E IL+ +PKGTH ++ E+ + + ++ + G +Y P+TG W+ D
Sbjct: 249 GAEYILRWLPKGTHQWSSFVTPEEMSMILQ---RASVDVKEIAGFVYNPITGRWLLSDDI 305
Query: 315 NIGNY 319
++ NY
Sbjct: 306 SV-NY 309
>Hs14754031 [H] KOG1270 Methyltransferases
Length = 369
Score = 117 bits (294), Expect = 2e-26
Identities = 86/279 (30%), Positives = 126/279 (44%), Gaps = 43/279 (15%)
Query: 48 SSGTSTSDDEIFHFQQLAPTWWDTWGSQRILHKMNLARLDFLQRTVRNQIKIKNDDVYIP 107
+S T+ E+ F LA WWD G LH MN R+ F++ + I
Sbjct: 87 TSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIP--------- 137
Query: 108 GFNHHDHLPGYVTKAIDQDIFNEVQRGLGEKKFDALDIGCGGGILSESFARLPFIQSVTA 167
+H PG LG K LD+GCGGG+L+E RL SV
Sbjct: 138 -----NHQPGKPL--------------LGMK---ILDVGCGGGLLTEPLGRLG--ASVIG 173
Query: 168 IDLTPECIEVAKAHAAKDPSIKDKIFYKFLPLEKVHGH----YDIVTMFEMLEHVDEPSE 223
ID E I+ A+ H + DP + +I Y+ LE++ +D V E++EHV +
Sbjct: 174 IDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIVEETAETFDAVVASEVVEHVIDLET 233
Query: 224 ILRQAWSKLKPNGVIFLSTINRDPISWFTTIFMGEQILKVVPKGTHHVEKYINSSEIKQW 283
L+ LKP G +F++TIN+ +S+ I EQI +VPKGTH EK+++ ++
Sbjct: 234 FLQCCCQVLKPGGSLFITTINKTQLSYALGIVFSEQIASIVPKGTHTWEKFVSPETLESI 293
Query: 284 FEDNVQGRYEILDTKGTMYLPLTG---WVEHDCTNIGNY 319
E N + G +Y P +G W E+ N Y
Sbjct: 294 LESN---GLSVQTVVGMLYNPFSGYWHWSENTSLNYAAY 329
>Hs8393177 [H] KOG1270 Methyltransferases
Length = 310
Score = 115 bits (288), Expect = 9e-26
Identities = 85/275 (30%), Positives = 125/275 (44%), Gaps = 43/275 (15%)
Query: 48 SSGTSTSDDEIFHFQQLAPTWWDTWGSQRILHKMNLARLDFLQRTVRNQIKIKNDDVYIP 107
+S T+ E+ F LA WWD G LH MN R+ F++ + I
Sbjct: 28 TSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIP--------- 78
Query: 108 GFNHHDHLPGYVTKAIDQDIFNEVQRGLGEKKFDALDIGCGGGILSESFARLPFIQSVTA 167
+H PG LG K LD+GCGGG+L+E RL SV
Sbjct: 79 -----NHQPGKPL--------------LGMK---ILDVGCGGGLLTEPLGRLG--ASVIG 114
Query: 168 IDLTPECIEVAKAHAAKDPSIKDKIFYKFLPLEKVHGH----YDIVTMFEMLEHVDEPSE 223
ID E I+ A+ H + DP + +I Y+ LE++ +D V E++EHV +
Sbjct: 115 IDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIVEETAETFDAVVASEVVEHVIDLET 174
Query: 224 ILRQAWSKLKPNGVIFLSTINRDPISWFTTIFMGEQILKVVPKGTHHVEKYINSSEIKQW 283
L+ LKP G +F++TIN+ +S+ I EQI +VPKGTH EK+++ ++
Sbjct: 175 FLQCCCQVLKPGGSLFITTINKTQLSYALGIVFSEQIAGIVPKGTHTWEKFVSPETLESI 234
Query: 284 FEDNVQGRYEILDTKGTMYLPLTG---WVEHDCTN 315
E N + G +Y P +G W E+ N
Sbjct: 235 LESN---GLSVQTVVGMLYNPFSGYWHWSENTSLN 266
>7298756 [H] KOG1270 Methyltransferases
Length = 231
Score = 103 bits (256), Expect = 4e-22
Identities = 67/211 (31%), Positives = 109/211 (50%), Gaps = 36/211 (17%)
Query: 78 LHKMNLARLDFLQRTVRNQIKIKNDDVYIPGFNHHDHLPGYVTKAIDQDIFNEVQRGLGE 137
LH +N R+ F++ + ++ +K PGYV N + LG+
Sbjct: 4 LHALNEIRVPFIRDGIVSRGTVK---------------PGYV---------NTTKVLLGQ 39
Query: 138 KKFDALDIGCGGGILSESFARLPFIQSVTAIDLTPECIEVAKAHA-AKDPSIKDKIFYKF 196
+ L++GCGGG+L+E ARL V IDL + IE A+ H P + + YK
Sbjct: 40 ---NILEVGCGGGLLTEHLARLG--AQVAGIDLGEKLIEAAREHLKCSSPELASNVVYKI 94
Query: 197 LPLEKVHGH-----YDIVTMFEMLEHVDEPSEILRQAWSKLKPNGVIFLSTINRDPISWF 251
P+++ H YD V + E+LEHV + +L + LKP G IF++T+N+ SWF
Sbjct: 95 EPVDQ-HAKANCECYDAVIVSEVLEHVKDKVSLLEASVRSLKPGGSIFITTLNKTIPSWF 153
Query: 252 TTIFMGEQILKVVPKGTHHVEKYINSSEIKQ 282
+ + E +L +VP+GTHH +K I+ ++++
Sbjct: 154 GGVLLSEYVLNLVPRGTHHWDKMISPLDVQR 184
>CE14946 [H] KOG1270 Methyltransferases
Length = 268
Score = 81.3 bits (199), Expect = 2e-15
Identities = 76/294 (25%), Positives = 118/294 (39%), Gaps = 58/294 (19%)
Query: 44 TFDKSSGTSTSDDEIFHFQQLAPTWWDTWGSQRILHKMNLARLDFLQRTVRNQIKIKNDD 103
T +S +S E+ F L+ W D G LH +N R+ ++ VR K+D
Sbjct: 19 TTSAASVSSIDVKEVEKFGDLSAEWADELGPFHALHSLNRIRVPWIVDNVR-----KSDQ 73
Query: 104 VYIPGFNHHDHLPGYVTKAIDQDIFNEVQRGLGEKKFDALDIGCGGGILSESFARLPFIQ 163
P +D+G GGG+LS AR F
Sbjct: 74 KAPPRL---------------------------------VDVGSGGGLLSIPLARSGF-- 98
Query: 164 SVTAIDLTPECIEVAKAHAAKDP----SIKDKIFYKFLPLE----KVHGH--YDIVTMFE 213
VT ID T + +E A P I ++ ++ +E K H YD V E
Sbjct: 99 DVTGIDATKQAVEAANQSLTAKPLQIAGISKRLRFEHTSVEDFCQKPHNKSAYDAVVASE 158
Query: 214 MLEHVDEPSEILRQAWSKLKPNGVIFLSTINRDPISWFTTIFMGEQILKVVPKGTHHVEK 273
++EHV + + +P +F++TINR +S I++ E +LK+VP G H EK
Sbjct: 159 IVEHVADLPGFIGCLAELARPGAPLFITTINRTWLSKLAAIWLAENVLKIVPPGVHDWEK 218
Query: 274 YINSSEIKQWFEDNVQGRYEILDTKGTMYLPLTG---WVEHDCTNIGNYFMAIK 324
+I +E+ E + + G M+ P+ W+E N G +A+K
Sbjct: 219 FITPAELTSHLE---KAGCRVTAVHGLMFHPVGNHWTWIESTQCNYG--ILAVK 267
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.138 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,020,561
Number of Sequences: 60738
Number of extensions: 936039
Number of successful extensions: 2621
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2600
Number of HSP's gapped (non-prelim): 10
length of query: 327
length of database: 30,389,216
effective HSP length: 107
effective length of query: 220
effective length of database: 23,890,250
effective search space: 5255855000
effective search space used: 5255855000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)