ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII0978 check: MH L KOG0991 Replication, recombination and repair Replication factor C, subunit RFC2
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII0978 340607 339648 -320
(320 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL094c [L] KOG0991 Replication factor C subunit RFC2 516 e-146
SPAC1687.03c [L] KOG0991 Replication factor C subunit RFC2 441 e-124
Hs4506487 [L] KOG0991 Replication factor C subunit RFC2 403 e-112
At1g63160 [L] KOG0991 Replication factor C subunit RFC2 400 e-111
7292439 [L] KOG0991 Replication factor C subunit RFC2 382 e-106
CE17139 [L] KOG0991 Replication factor C subunit RFC2 355 5e-98
ECU09g1330 [L] KOG0991 Replication factor C subunit RFC2 236 3e-62
Hs6677723 [L] KOG0990 Replication factor C subunit RFC5 205 8e-53
Hs4506491 [L] KOG0989 Replication factor C subunit RFC4 195 8e-50
YNL290w [L] KOG0990 Replication factor C subunit RFC5 194 1e-49
YJR068w [L] KOG0989 Replication factor C subunit RFC4 194 1e-49
At1g77470 [L] KOG0990 Replication factor C subunit RFC5 194 2e-49
At1g21690 [L] KOG0989 Replication factor C subunit RFC4 193 2e-49
SPAC23D3.02 [L] KOG0989 Replication factor C subunit RFC4 181 1e-45
CE29044 [L] KOG0990 Replication factor C subunit RFC5 181 1e-45
7297692 [L] KOG0990 Replication factor C subunit RFC5 178 8e-45
ECU02g0290 [L] KOG0990 Replication factor C subunit RFC5 165 7e-41
7293390 [L] KOG0989 Replication factor C subunit RFC4 156 4e-38
CE01268 [L] KOG0989 Replication factor C subunit RFC4 154 1e-37
SPAPJ698.01c [L] KOG0990 Replication factor C subunit RFC5 120 2e-27
ECU02g0680 [L] KOG0989 Replication factor C subunit RFC4 116 4e-26
SPAC27E2.10c [L] KOG0990 Replication factor C subunit RFC5 114 2e-25
CE05396 [DL] KOG2035 Replication factor C subunit RFC3 114 2e-25
ECU10g0780i [DL] KOG2035 Replication factor C subunit RFC3 106 4e-23
At5g27740 [DL] KOG2035 Replication factor C subunit RFC3 106 4e-23
ECU05g1530 [L] KOG1968 Replication factor C subunit RFC1 (large ... 100 4e-21
Hs4506489 [DL] KOG2035 Replication factor C subunit RFC3 96 9e-20
YBR087w [DL] KOG2035 Replication factor C subunit RFC3 95 2e-19
SPBC83.14c [DL] KOG2035 Replication factor C subunit RFC3 94 3e-19
YOR217w [L] KOG1968 Replication factor C subunit RFC1 (large sub... 83 5e-16
SPBC23E6.07c [L] KOG1968 Replication factor C subunit RFC1 (larg... 79 9e-15
7297827 [DL] KOG2035 Replication factor C subunit RFC3 69 9e-12
SPBC902.02c [DL] KOG1969 DNA replication checkpoint protein CHL1... 68 2e-11
At1g14460 [L] KOG0989 Replication factor C subunit RFC4 68 2e-11
CE20613 [L] KOG1968 Replication factor C subunit RFC1 (large sub... 67 3e-11
7296805 [L] KOG1968 Replication factor C subunit RFC1 (large sub... 66 8e-11
Hs22045214 [L] KOG0991 Replication factor C subunit RFC2 62 8e-10
At2g02480 [L] KOG0989 Replication factor C subunit RFC4 62 1e-09
Hs15011931 [L] KOG1968 Replication factor C subunit RFC1 (large ... 59 1e-08
At1g24290 [L] KOG2028 ATPase related to the helicase subunit of ... 57 4e-08
Hs14777079 [DL] KOG1969 DNA replication checkpoint protein CHL12... 55 2e-07
Hs18426902 [L] KOG2028 ATPase related to the helicase subunit of... 52 1e-06
At5g45720 [L] KOG0989 Replication factor C subunit RFC4 52 1e-06
SPAC26H5.02c [L] KOG2028 ATPase related to the helicase subunit ... 49 1e-05
>YOL094c [L] KOG0991 Replication factor C subunit RFC2
Length = 323
Score = 516 bits (1329), Expect = e-146
Identities = 258/321 (80%), Positives = 291/321 (90%), Gaps = 1/321 (0%)
Query: 1 MSYATKLELPWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIH 60
MS L+LPWVEKYRP +L DIVGN++T+ RLQ IA DGNMPHMIISG+PGIGKTTS+H
Sbjct: 1 MSKTLSLQLPWVEKYRPQVLSDIVGNKETIDRLQQIAKDGNMPHMIISGMPGIGKTTSVH 60
Query: 61 CLAHELLGDAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAGKHKIIILDEADSMT 120
CLAHELLG +Y+ VLELNASDDRGI+VVRNQIKHFAQKK LP GKHKI+ILDEADSMT
Sbjct: 61 CLAHELLGRSYADGVLELNASDDRGIDVVRNQIKHFAQKKLHLPPGKHKIVILDEADSMT 120
Query: 121 SGAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIK 180
+GAQQALRRTMELYSN+TRFAFACNQSNKIIEPLQSRCAILRYSKL+DE VLKRLL+IIK
Sbjct: 121 AGAQQALRRTMELYSNSTRFAFACNQSNKIIEPLQSRCAILRYSKLSDEDVLKRLLQIIK 180
Query: 181 LEDVQYTNDGLEAIIFTAEGDMRQAINNLQSTVAGFGLVNGENVFQIVDSPHPLIVKRML 240
LEDV+YTNDGLEAIIFTAEGDMRQAINNLQSTVAG GLVN +NVF+IVDSPHPLIVK+ML
Sbjct: 181 LEDVKYTNDGLEAIIFTAEGDMRQAINNLQSTVAGHGLVNADNVFKIVDSPHPLIVKKML 240
Query: 241 LSGSLDESLQYLK-ELWVKGYSAVDIVITCFRVMKNLDEVKETVRLEMIKEIGFTHMRIL 299
L+ +L++S+Q L+ +LW KGYS++DIV T FRV KNL +VKE+VRLEMIKEIG THMRIL
Sbjct: 241 LASNLEDSIQILRTDLWKKGYSSIDIVTTSFRVTKNLAQVKESVRLEMIKEIGLTHMRIL 300
Query: 300 EGVGTHLQLSGMLAKIQKLKS 320
EGVGT+LQL+ MLAKI KL +
Sbjct: 301 EGVGTYLQLASMLAKIHKLNN 321
>SPAC1687.03c [L] KOG0991 Replication factor C subunit RFC2
Length = 342
Score = 441 bits (1135), Expect = e-124
Identities = 221/313 (70%), Positives = 262/313 (83%), Gaps = 3/313 (0%)
Query: 8 ELPWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELL 67
ELPWVEKYRP +L DIVGNE+T+ RL+ IA +GNMPH++ISG+PGIGKTTSI CLAH LL
Sbjct: 20 ELPWVEKYRPIVLDDIVGNEETIDRLKVIAKEGNMPHLVISGMPGIGKTTSILCLAHALL 79
Query: 68 GDAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAGKHKIIILDEADSMTSGAQQAL 127
G AY + VLELNASD+RGI+VVRN+IK FAQKK LP G+HKIIILDEADSMT+GAQQAL
Sbjct: 80 GPAYKEGVLELNASDERGIDVVRNRIKAFAQKKVILPPGRHKIIILDEADSMTAGAQQAL 139
Query: 128 RRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYT 187
RRTME+YSNTTRFA ACNQSNKIIEP+QSRCAILRYS+LTD+QVL+RLL I K E V YT
Sbjct: 140 RRTMEIYSNTTRFALACNQSNKIIEPIQSRCAILRYSRLTDQQVLQRLLNICKAEKVNYT 199
Query: 188 NDGLEAIIFTAEGDMRQAINNLQSTVAGFGLVNGENVFQIVDSPHPLIVKRMLL---SGS 244
+DGL A+I TAEGDMRQA+NNLQSTVAGFGLVNGENVF++ D P P+ + ML SG+
Sbjct: 200 DDGLAALIMTAEGDMRQAVNNLQSTVAGFGLVNGENVFRVADQPSPVAIHAMLTACQSGN 259
Query: 245 LDESLQYLKELWVKGYSAVDIVITCFRVMKNLDEVKETVRLEMIKEIGFTHMRILEGVGT 304
+D +L+ L+ +W G+SAVDIV FRV+K +D + E RLEM+KEIG THM ILEGV T
Sbjct: 260 IDVALEKLQGIWDLGFSAVDIVTNMFRVVKTMDSIPEFSRLEMLKEIGQTHMIILEGVQT 319
Query: 305 HLQLSGMLAKIQK 317
LQLSG++ ++ K
Sbjct: 320 LLQLSGLVCRLAK 332
>Hs4506487 [L] KOG0991 Replication factor C subunit RFC2
Length = 354
Score = 403 bits (1035), Expect = e-112
Identities = 201/311 (64%), Positives = 251/311 (80%), Gaps = 4/311 (1%)
Query: 8 ELPWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELL 67
ELPWVEKYRP L +IVGNEDTV RL+ A +GN+P++II+G PG GKTTSI CLA LL
Sbjct: 35 ELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALL 94
Query: 68 GDAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAGKHKIIILDEADSMTSGAQQAL 127
G A A+LELNAS+DRGI+VVRN+IK FAQ+K TLP G+HKIIILDEADSMT GAQQAL
Sbjct: 95 GPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQAL 154
Query: 128 RRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYT 187
RRTME+YS TTRFA ACN S+KIIEP+QSRCA+LRY+KLTD Q+L RL+ +I+ E V YT
Sbjct: 155 RRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYT 214
Query: 188 NDGLEAIIFTAEGDMRQAINNLQSTVAGFGLVNGENVFQIVDSPHPLIVKRML---LSGS 244
+DGLEAIIFTA+GDMRQA+NNLQST +GFG +N ENVF++ D PHPL+VK M+ ++ +
Sbjct: 215 DDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNAN 274
Query: 245 LDESLQYLKELWVKGYSAVDIVITCFRVMKNLDEVKETVRLEMIKEIGFTHMRILEGVGT 304
+DE+ + L LW GYS DI+ FRV K ++ E ++LE IKEIG+THM+I EGV +
Sbjct: 275 IDEAYKILAHLWHLGYSPEDIIGNIFRVCKTF-QMAEYLKLEFIKEIGYTHMKIAEGVNS 333
Query: 305 HLQLSGMLAKI 315
LQ++G+LA++
Sbjct: 334 LLQMAGLLARL 344
>At1g63160 [L] KOG0991 Replication factor C subunit RFC2
Length = 333
Score = 400 bits (1027), Expect = e-111
Identities = 201/309 (65%), Positives = 247/309 (79%), Gaps = 4/309 (1%)
Query: 10 PWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELLGD 69
PWVEKYRP + DIVGNED V RLQ IA DGNMP++I+SG PG GKTTSI LAHELLG
Sbjct: 16 PWVEKYRPSKVVDIVGNEDAVSRLQVIARDGNMPNLILSGPPGTGKTTSILALAHELLGT 75
Query: 70 AYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAGKHKIIILDEADSMTSGAQQALRR 129
Y +AVLELNASDDRGI+VVRN+IK FAQKK TLP G+HK++ILDEADSMTSGAQQALRR
Sbjct: 76 NYKEAVLELNASDDRGIDVVRNKIKMFAQKKVTLPPGRHKVVILDEADSMTSGAQQALRR 135
Query: 130 TMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYTND 189
T+E+YSN+TRFA ACN S KIIEP+QSRCA++R+S+L+D+Q+L RLL ++ E V Y +
Sbjct: 136 TIEIYSNSTRFALACNTSAKIIEPIQSRCALVRFSRLSDQQILGRLLVVVAAEKVPYVPE 195
Query: 190 GLEAIIFTAEGDMRQAINNLQSTVAGFGLVNGENVFQIVDSPHPLIVK---RMLLSGSLD 246
GLEAIIFTA+GDMRQA+NNLQ+T +GF VN ENVF++ D PHPL VK R +L D
Sbjct: 196 GLEAIIFTADGDMRQALNNLQATFSGFSFVNQENVFKVCDQPHPLHVKNIVRNVLESKFD 255
Query: 247 ESLQYLKELWVKGYSAVDIVITCFRVMKNLDEVKETVRLEMIKEIGFTHMRILEGVGTHL 306
+ LK+L+ GYS DI+ T FR++KN D + E ++LE +KE GF HMRI +GVG++L
Sbjct: 256 IACDGLKQLYDLGYSPTDIITTLFRIIKNYD-MAEYLKLEFMKETGFAHMRICDGVGSYL 314
Query: 307 QLSGMLAKI 315
QL G+LAK+
Sbjct: 315 QLCGLLAKL 323
>7292439 [L] KOG0991 Replication factor C subunit RFC2
Length = 331
Score = 382 bits (982), Expect = e-106
Identities = 185/310 (59%), Positives = 244/310 (78%), Gaps = 4/310 (1%)
Query: 9 LPWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELLG 68
LPW+EKYRP K+IVGNEDTV RL A GN P++II+G PG+GKTT+I CLA LLG
Sbjct: 16 LPWIEKYRPVKFKEIVGNEDTVARLSVFATQGNAPNIIIAGPPGVGKTTTIQCLARILLG 75
Query: 69 DAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAGKHKIIILDEADSMTSGAQQALR 128
D+Y +AVLELNAS++RGI+VVRN+IK FAQ+K TLP G+HKI+ILDEADSMT GAQQALR
Sbjct: 76 DSYKEAVLELNASNERGIDVVRNKIKMFAQQKVTLPRGRHKIVILDEADSMTEGAQQALR 135
Query: 129 RTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYTN 188
RTME+YS+TTRFA ACN S KIIEP+QSRCA+LR++KL+D QVL +L+E+ K E + YT
Sbjct: 136 RTMEIYSSTTRFALACNTSEKIIEPIQSRCAMLRFTKLSDAQVLAKLIEVAKWEKLNYTE 195
Query: 189 DGLEAIIFTAEGDMRQAINNLQSTVAGFGLVNGENVFQIVDSPHPLIVKRML---LSGSL 245
DGLEAI+FTA+GDMRQ +NNLQST GFG + ENVF++ D PHP +++ M+ + +
Sbjct: 196 DGLEAIVFTAQGDMRQGLNNLQSTAQGFGDITAENVFKVCDEPHPKLLEEMIHHCAANDI 255
Query: 246 DESLQYLKELWVKGYSAVDIVITCFRVMKNLDEVKETVRLEMIKEIGFTHMRILEGVGTH 305
++ + L +LW GYS DI+ FRV K ++ + E ++L+ I+EIG THM+I++G+ +
Sbjct: 256 HKAYKILAKLWKLGYSPEDIIANIFRVCKRIN-IDEHLKLDFIREIGITHMKIIDGINSL 314
Query: 306 LQLSGMLAKI 315
LQL+ +LAK+
Sbjct: 315 LQLTALLAKL 324
>CE17139 [L] KOG0991 Replication factor C subunit RFC2
Length = 334
Score = 355 bits (911), Expect = 5e-98
Identities = 185/327 (56%), Positives = 246/327 (74%), Gaps = 7/327 (2%)
Query: 1 MSYATKLEL-PWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSI 59
MS + K +L PWVEKYRP +L DIVGNE+ V+RL+ I +GN+P++++SG PG GKTTS+
Sbjct: 1 MSKSEKQQLAPWVEKYRPKVLADIVGNENIVERLKVIGHEGNVPNIVLSGPPGCGKTTSV 60
Query: 60 HCLAHELLGDAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAGKHKIIILDEADSM 119
LA ELLGD +AVLELNASD+RGI+VVR++IK FAQ K TLP G+HKIIILDEADSM
Sbjct: 61 WALARELLGDKVKEAVLELNASDERGIDVVRHRIKTFAQTKVTLPEGRHKIIILDEADSM 120
Query: 120 TSGAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEII 179
T GAQQALRRTME+Y+ TTRFA ACNQS KIIEP+QSRCA+LRY+KL+ Q+L R+ E+
Sbjct: 121 TDGAQQALRRTMEMYTKTTRFALACNQSEKIIEPIQSRCALLRYTKLSPVQLLTRVKEVA 180
Query: 180 KLEDVQYTNDGLEAIIFTAEGDMRQAINNLQSTVAGFGLVNGENVFQIVDSPHPLIVKRM 239
K E V Y + GLEAI+FTA+GDMRQA+NNLQ+TV + LVN ENV ++ D PHP ++ +M
Sbjct: 181 KAEKVNYDDGGLEAILFTAQGDMRQALNNLQATVNAYELVNKENVLKVCDEPHPDLMIKM 240
Query: 240 L---LSGSLDESLQYLKELWVKGYSAVDIVITCFRVMKNLD---EVKETVRLEMIKEIGF 293
L E+ + + E G+S+ DIV T FRV+K ++ V E +R+E I++I
Sbjct: 241 LHYCTDRKFFEASKIIHEFHRLGFSSDDIVSTLFRVVKTVELSKNVSEQLRMEYIRQIAM 300
Query: 294 THMRILEGVGTHLQLSGMLAKIQKLKS 320
HMRI++G+ + LQLS ++A + ++ +
Sbjct: 301 CHMRIVQGLTSKLQLSRLIADLCRVSA 327
>ECU09g1330 [L] KOG0991 Replication factor C subunit RFC2
Length = 309
Score = 236 bits (603), Expect = 3e-62
Identities = 128/312 (41%), Positives = 199/312 (63%), Gaps = 13/312 (4%)
Query: 12 VEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELLGDAY 71
V KY+P ++DIVGNE T++ + + +MPH++ +G PG GKTT LA LLG+
Sbjct: 5 VNKYQPSEIQDIVGNEATMELVSLMIESRDMPHLLFTGPPGTGKTTCAKILARRLLGN-- 62
Query: 72 SQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAGKHKIIILDEADSMTSGAQQALRRTM 131
+ +LELNASD+RGI+ VR IK FAQ++ + + KIIILDEADSMT+ AQQA+RR M
Sbjct: 63 KEGLLELNASDERGIDTVRTTIKSFAQRR--VKDCEFKIIILDEADSMTTTAQQAMRRVM 120
Query: 132 ELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYTNDGL 191
E++S+ RF CN KI EP+QSRCAILR+ ++ +LKRL EI + E ++ T + L
Sbjct: 121 EIHSSECRFILICNVFTKIFEPIQSRCAILRFDRIEQSVILKRLKEISEGEGIRITAEAL 180
Query: 192 EAIIFTAEGDMRQAINNLQSTVAGFGLVNGENVFQIVDSPHPLIVKRM---LLSGSLDES 248
+ ++ ++GDMRQ++N LQ+ + G V+ + + +I+ P P ++++ LL ++E+
Sbjct: 181 DLVVELSDGDMRQSLNILQACINSPGTVDQDYIIKIIGLPSPKRIEKVLQRLLKREVEEA 240
Query: 249 LQYLKELWVKGYSAVDIVITCFRVMKNLDEVKETVRLEMIKEIGFTHMRILEGVGTHLQL 308
L+ E+W + + +D++ + FR KN++ E++K IG ++RI EGV + LQ
Sbjct: 241 LEMFDEIWEEKFDPLDLINSFFRAAKNMES------YELLKVIGLANLRISEGVNSRLQF 294
Query: 309 SGMLAKIQKLKS 320
GM I + S
Sbjct: 295 YGMFWDILDMGS 306
>Hs6677723 [L] KOG0990 Replication factor C subunit RFC5
Length = 340
Score = 205 bits (521), Expect = 8e-53
Identities = 119/319 (37%), Positives = 182/319 (56%), Gaps = 8/319 (2%)
Query: 4 ATKLE-LPWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCL 62
ATK+ LPWVEKYRP L D++ ++D + +Q + +PH+++ G PG GKT++I
Sbjct: 14 ATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILAC 73
Query: 63 AHELLGDA-YSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAGKHKIIILDEADSMTS 121
A +L D + VLELNASDDRGI+++R I FA + G K++ILDEAD+MT
Sbjct: 74 AKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-FKLVILDEADAMTQ 132
Query: 122 GAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKL 181
AQ ALRR +E ++ TRF CN +KII LQSRC R+ LT E ++ RL +++
Sbjct: 133 DAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEE 192
Query: 182 EDVQYTNDGLEAIIFTAEGDMRQAINNLQSTVAGFGLVNGENVFQIVDSPHPLIVKRML- 240
E V + DG++A++ + GDMR+A+N LQST FG V E V+ P + +L
Sbjct: 193 EKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILD 252
Query: 241 --LSGSLDESLQYLKEL-WVKGYSAVDIVITCFRVMKNLDEVKETVRLEMIKEIGFTHMR 297
L+ + + + EL +KG + DI+ + +D +VR+ ++ ++ R
Sbjct: 253 WMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVD-FPSSVRIHLLTKMADIEYR 311
Query: 298 ILEGVGTHLQLSGMLAKIQ 316
+ G +QLS ++A Q
Sbjct: 312 LSVGTNEKIQLSSLIAAFQ 330
>Hs4506491 [L] KOG0989 Replication factor C subunit RFC4
Length = 363
Score = 195 bits (495), Expect = 8e-50
Identities = 122/326 (37%), Positives = 190/326 (57%), Gaps = 23/326 (7%)
Query: 9 LPWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELLG 68
+PWVEKYRP + ++ E+ V L+ ++P+++ G PG GKT++I A EL G
Sbjct: 38 VPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFG 97
Query: 69 -DAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCT------LPAGKHKIIILDEADSMTS 121
+ + VLELNASD+RGI+VVR ++K+FAQ + P KI+ILDEADSMTS
Sbjct: 98 PELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTS 157
Query: 122 GAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKL 181
AQ ALRRTME S TTRF CN ++IIEPL SRC+ R+ L+D+ +RLL+I K
Sbjct: 158 AAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKK 217
Query: 182 EDVQYTNDGLEAIIFTAEGDMRQAINNLQSTVAGFGLVNGENVFQ--IVDSPHPLIVKRM 239
E+V+ +++G+ ++ +EGD+R+AI LQS L G+ + + I D + +++
Sbjct: 218 ENVKISDEGIAYLVKVSEGDLRKAITFLQSATR---LTGGKEITEKVITDIAGVIPAEKI 274
Query: 240 ------LLSGSLDESLQYLKELWVKGYSAVDIVITCFRVM--KNLDEVKETVRLEMIKEI 291
SGS D+ +K+L +G++A +V V+ NL + ++++ E + E+
Sbjct: 275 DGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEV 334
Query: 292 GFTHMRILEGVGTHLQLSGMLAKIQK 317
+ +G HLQL + A + +
Sbjct: 335 ---DKCLADGADEHLQLISLCATVMQ 357
>YNL290w [L] KOG0990 Replication factor C subunit RFC5
Length = 340
Score = 194 bits (494), Expect = 1e-49
Identities = 110/323 (34%), Positives = 182/323 (56%), Gaps = 14/323 (4%)
Query: 5 TKLELPWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAH 64
+K LPWVEKYRP L ++ G + + ++ +G +PH++ G PG GKT++I LA
Sbjct: 9 SKENLPWVEKYRPETLDEVYGQNEVITTVRKFVDEGKLPHLLFYGPPGTGKTSTIVALAR 68
Query: 65 ELLGDAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAGKHKIIILDEADSMTSGAQ 124
E+ G YS VLELNASDDRGI+VVRNQIK FA + G K+IILDEAD+MT+ AQ
Sbjct: 69 EIYGKNYSNMVLELNASDDRGIDVVRNQIKDFASTRQIFSKG-FKLIILDEADAMTNAAQ 127
Query: 125 QALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDV 184
ALRR +E Y+ TRF N ++K+ L SRC R+ L E + +R+ ++ E +
Sbjct: 128 NALRRVIERYTKNTRFCVLANYAHKLTPALLSRCTRFRFQPLPQEAIERRIANVLVHEKL 187
Query: 185 QYTNDGLEAIIFTAEGDMRQAINNLQSTVAGF-----GLVNGENVFQIVDSPHPLIVKRM 239
+ + + +A+I + GDMR+ +N LQS A ++ + +++ +P P +K +
Sbjct: 188 KLSPNAEKALIELSNGDMRRVLNVLQSCKATLDNPDEDEISDDVIYECCGAPRPSDLKAV 247
Query: 240 LLS------GSLDESLQYLKELWVKGYSAVDIVITCFRVMKNLDEVKETVRLEMIKEIGF 293
L S G+ +L ++ KG + +D++ +++++ + E R+ ++ ++
Sbjct: 248 LKSILEDDWGTAHYTLNKVRS--AKGLALIDLIEGIVKILEDYELQNEETRVHLLTKLAD 305
Query: 294 THMRILEGVGTHLQLSGMLAKIQ 316
I +G +Q S ++ I+
Sbjct: 306 IEYSISKGGNDQIQGSAVIGAIK 328
>YJR068w [L] KOG0989 Replication factor C subunit RFC4
Length = 353
Score = 194 bits (493), Expect = 1e-49
Identities = 124/329 (37%), Positives = 177/329 (53%), Gaps = 21/329 (6%)
Query: 10 PWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELLG- 68
PWVEKYRP L ++ + V L+ N+PHM+ G PG GKT++I L EL G
Sbjct: 26 PWVEKYRPKNLDEVTAQDHAVTVLKKTLKSANLPHMLFYGPPGTGKTSTILALTKELYGP 85
Query: 69 DAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAGKH----------KIIILDEADS 118
D +LELNASD+RGI +VR ++K+FA+ + P+ KH KIIILDEADS
Sbjct: 86 DLMKSRILELNASDERGISIVREKVKNFARLTVSKPS-KHDLENYPCPPYKIIILDEADS 144
Query: 119 MTSGAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEI 178
MT+ AQ ALRRTME YS TRF CN +II+PL SRC+ R+ L + RL I
Sbjct: 145 MTADAQSALRRTMETYSGVTRFCLICNYVTRIIDPLASRCSKFRFKALDASNAIDRLRFI 204
Query: 179 IKLEDVQYTNDGLEAIIFTAEGDMRQAINNLQSTVAGFG-LVNGENV--FQIVD----SP 231
+ E+V+ + LE I+ + GD+R+ I LQS G L +G+N+ Q+ + P
Sbjct: 205 SEQENVKCDDGVLERILDISAGDLRRGITLLQSASKGAQYLGDGKNITSTQVEELAGVVP 264
Query: 232 HPLIVK--RMLLSGSLDESLQYLKELWVKGYSAVDIVITCFRVMKNLDEVKETVRLEMIK 289
H ++++ + SG DE +Y+ G+SA +V D + ++
Sbjct: 265 HDILIEIVEKVKSGDFDEIKKYVNTFMKSGWSAASVVNQLHEYYITNDNFDTNFKNQISW 324
Query: 290 EIGFTHMRILEGVGTHLQLSGMLAKIQKL 318
+ T R+ G H+QL +L KI +L
Sbjct: 325 LLFTTDSRLNNGTNEHIQLLNLLVKISQL 353
>At1g77470 [L] KOG0990 Replication factor C subunit RFC5
Length = 369
Score = 194 bits (492), Expect = 2e-49
Identities = 121/326 (37%), Positives = 189/326 (57%), Gaps = 18/326 (5%)
Query: 10 PWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELLGD 69
PWVEKYRP L D+ + D + + + + +PH+++ G PG GKT++I +A +L G
Sbjct: 40 PWVEKYRPQSLDDVAAHRDIIDTIDRLTNENKLPHLLLYGPPGTGKTSTILAVARKLYGP 99
Query: 70 AYSQAVLELNASDDRGIEVVRNQIKHFAQ-KKCTLPAGKHKIIILDEADSMTSGAQQALR 128
Y +LELNASDDRGI+VVR QI+ FA + +L K+++LDEAD+MT AQ ALR
Sbjct: 100 KYRNMILELNASDDRGIDVVRQQIQDFASTQSFSLGKSSVKLVLLDEADAMTKDAQFALR 159
Query: 129 RTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYTN 188
R +E Y+ +TRFA N NKII LQSRC R++ L + +RL +I+ E + ++
Sbjct: 160 RVIEKYTKSTRFALIGNHVNKIIPALQSRCTRFRFAPLDGVHMSQRLKHVIEAERLVVSD 219
Query: 189 DGLEAIIFTAEGDMRQAINNLQST-VAGFGL-------VNGENVFQIVDSPHPLIVKRM- 239
GL A++ + GDMR+A+N LQST +A + + E+V+ +P P ++++
Sbjct: 220 CGLAALVRLSNGDMRKALNILQSTHMASKEITEEESKQITEEDVYLCTGNPLPKDIEQIS 279
Query: 240 --LLSGSLDESLQYLKELWV-KGYSAVDIV--ITCFRVMKNLDEVKETVRLEMIKEIGFT 294
LL+ DE + + E+ KG + VDIV IT F + K ++ VR+++I ++
Sbjct: 280 HWLLNKPFDECYKDVSEIKTRKGLAIVDIVKEITLF-IFK--IKMPSAVRVQLINDLADI 336
Query: 295 HMRILEGVGTHLQLSGMLAKIQKLKS 320
R+ G LQL +++ +S
Sbjct: 337 EYRLSFGCNDKLQLGAIISTFTHARS 362
>At1g21690 [L] KOG0989 Replication factor C subunit RFC4
Length = 336
Score = 193 bits (491), Expect = 2e-49
Identities = 121/293 (41%), Positives = 159/293 (53%), Gaps = 25/293 (8%)
Query: 10 PWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELLG- 68
PWVEKYRP +KD+ E+ V+ L + PHM+ G PG GKTT+ +AH+L G
Sbjct: 10 PWVEKYRPKQVKDVAHQEEVVRVLTNTLQTADCPHMLFYGPPGTGKTTTALAIAHQLFGP 69
Query: 69 DAYSQAVLELNASDDRGIEVVRNQIKHFA-------QKKCTLPAGKHKIIILDEADSMTS 121
+ Y VLELNASDDRGI VVR +IK FA ++ P KIIILDEADSMT
Sbjct: 70 ELYKSRVLELNASDDRGINVVRTKIKDFAAVAVGSNHRQSGYPCPSFKIIILDEADSMTE 129
Query: 122 GAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKL 181
AQ ALRRTME YS TRF F CN ++IIEPL SRCA R+ L++E + R+L I
Sbjct: 130 DAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNE 189
Query: 182 EDVQYTNDGLEAIIFTAEGDMRQAINNLQSTVAGFG-------LVNGENV-FQIVDSPH- 232
E + + L + ++GD+R+AI LQS FG L+N V ++ H
Sbjct: 190 EGLSLDGEALSTLSSISQGDLRRAITYLQSATRLFGSTITSTDLLNVSGVRMKLTQYLHK 249
Query: 233 ----PLIVKRMLL----SGSLDESLQYLKELWVKGYSAVDIVITCFRVMKNLD 277
PL V L SG D + + + + +GY A I+ F ++ D
Sbjct: 250 CMVVPLEVVNKLFTACKSGDFDIANKEVDNIVAEGYPASQIINQLFDIVAEAD 302
>SPAC23D3.02 [L] KOG0989 Replication factor C subunit RFC4
Length = 340
Score = 181 bits (460), Expect = 1e-45
Identities = 117/324 (36%), Positives = 173/324 (53%), Gaps = 17/324 (5%)
Query: 6 KLELPWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHE 65
K +PWVE YRP L + E TVQ L+ N+PHM+ G PG GKT++I L+ E
Sbjct: 16 KKSIPWVELYRPKTLDQVSSQESTVQVLKKTLLSNNLPHMLFYGSPGTGKTSTILALSRE 75
Query: 66 LLGDAYSQA-VLELNASDDRGIEVVRNQIKHFAQKKCT-----LPAGKHKIIILDEADSM 119
L G ++ VLELNASD+RGI ++R ++K FA+ T P KIIILDEADSM
Sbjct: 76 LFGPQLMKSRVLELNASDERGISIIREKVKSFAKTTVTNKVDGYPCPPFKIIILDEADSM 135
Query: 120 TSGAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEII 179
T AQ ALRRTME Y+ TRF CN +II+PL SRC+ R+ L +E ++KRL I
Sbjct: 136 TQDAQAALRRTMESYARITRFCLICNYMTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIA 195
Query: 180 KLEDVQYTNDGLEAIIFTAEGDMRQAINNLQSTVAGFGLVNGENV----FQIVDSPHPLI 235
+ V + A++ + GDMR+AI LQS L G + + + P
Sbjct: 196 ADQAVSMEPGVVNALVECSGGDMRKAITFLQSAA---NLHQGTPITISSVEELAGAVPYN 252
Query: 236 VKRMLLSGSLDESLQYL----KELWVKGYSAVDIVITCFRVMKNLDEVKETVRLEMIKEI 291
+ R LL + +++ + +++ +GYS I+ V+ + + V+ ++ ++
Sbjct: 253 IIRSLLDTAYTKNVSNIETLSRDVAAEGYSTGIILSQLHDVLLKEETLSSPVKYKIFMKL 312
Query: 292 GFTHMRILEGVGTHLQLSGMLAKI 315
R+ +G LQL +L+ I
Sbjct: 313 SEVDKRLNDGADETLQLLDLLSSI 336
>CE29044 [L] KOG0990 Replication factor C subunit RFC5
Length = 388
Score = 181 bits (459), Expect = 1e-45
Identities = 116/355 (32%), Positives = 180/355 (50%), Gaps = 40/355 (11%)
Query: 1 MSYATKLELPWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIH 60
M+ T LPWVEKYRP L ++V +E V+ L + +PH++ G PG GKTT++
Sbjct: 21 MTTTTASNLPWVEKYRPSKLDELVAHEQIVKTLTKFIENRTLPHLLFYGPPGTGKTTTVL 80
Query: 61 CLAHELLGDA-YSQAVLELNASDDRGIEVVRNQIKHFAQKKC-----------TLPAGKH 108
A ++ + VLELNASD+RGI+VVRN I +FAQ K T+P
Sbjct: 81 AAARQMYSPTKMASMVLELNASDERGIDVVRNTIVNFAQTKGLQAFSTSSNTGTVP---F 137
Query: 109 KIIILDEADSMTSGAQQALRR--------------------TMELYSNTTRFAFACNQSN 148
K++ILDEAD+MT AQ ALRR +E Y++ RF CN
Sbjct: 138 KLVILDEADAMTKDAQNALRRLDKTDYEQNIIIHNVNIYFRVIEKYTDNVRFCIICNYLA 197
Query: 149 KIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAINN 208
I+ +QSRC R++ L + ++ RL I++ E ++ T DG +A++ ++GDMR IN
Sbjct: 198 SIVPAIQSRCTRFRFAPLDQKLIVPRLEYIVETEQLKMTPDGKDALLIVSKGDMRTVINT 257
Query: 209 LQSTVAGFGLVNGENVFQIVDSPHPLIVKRMLLSGSLDESLQYLK----ELWVKGYSAVD 264
LQST F V+ V+Q + P P +K ++ + D S + + +L+ GY+ D
Sbjct: 258 LQSTAMSFDTVSENTVYQCIGQPTPKEMKEVVKTLLNDPSKKCMNTIQTKLFENGYALQD 317
Query: 265 IVITCFRVMKNLDEVKETVRLEMIKEIGFTHMRILEGVGTHLQLSGMLAKIQKLK 319
++ + LD + + +I +G + G QL+ ++A + K
Sbjct: 318 VITHLHDFVFTLD-IPDEAMSAIITGLGEVEENLSTGCSNETQLAAVVAAFFEAK 371
>7297692 [L] KOG0990 Replication factor C subunit RFC5
Length = 297
Score = 178 bits (452), Expect = 8e-45
Identities = 109/278 (39%), Positives = 165/278 (59%), Gaps = 8/278 (2%)
Query: 42 MPHMIISGLPGIGKTTSIHCLAHELLG-DAYSQAVLELNASDDRGIEVVRNQIKHFAQKK 100
+PH++ G PG GKT++I A +L + VLELNASDDRGI +VR QI +FA +
Sbjct: 9 LPHLLFYGPPGTGKTSTILACARQLYSPQQFKSMVLELNASDDRGIGIVRGQILNFASTR 68
Query: 101 CTLPAGKHKIIILDEADSMTSGAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAI 160
T+ K+IILDEAD+MT+ AQ ALRR +E Y++ RF CN +KII LQSRC
Sbjct: 69 -TIFCDTFKLIILDEADAMTNDAQNALRRIIEKYTDNVRFCVICNYLSKIIPALQSRCTR 127
Query: 161 LRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAINNLQSTVAGFGLVN 220
R++ L+ +Q++ RL +II+ E VQ T DG A++ A+GDMR+ +N LQSTV F VN
Sbjct: 128 FRFAPLSQDQMMPRLEKIIEAEAVQITEDGKRALLTLAKGDMRKVLNVLQSTVMAFDTVN 187
Query: 221 GENVFQIVDSP----HPLIVKRMLLSGSLDESLQYLKEL-WVKGYSAVDIVITCFRVMKN 275
+NV+ V P I+K +L SL++S + ++ + +G + DI+ +
Sbjct: 188 EDNVYMCVGYPLRQDIEQILKALLSGSSLEDSFKTVESAKYARGLALEDIITELHLFVMR 247
Query: 276 LDEVKETVRLEMIKEIGFTHMRILEGVGTHLQLSGMLA 313
L E+ +V ++I ++ R+ +G Q + ++A
Sbjct: 248 L-ELPMSVMNKLIVKLAQIEERLAKGCTEVAQTAALVA 284
>ECU02g0290 [L] KOG0990 Replication factor C subunit RFC5
Length = 305
Score = 165 bits (418), Expect = 7e-41
Identities = 94/212 (44%), Positives = 130/212 (60%), Gaps = 10/212 (4%)
Query: 13 EKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELLGDAYS 72
EKYRP L ++VGN + V LQ+I++ G +P+M+ G PG GKTTSI +A+ L
Sbjct: 7 EKYRPGSLLEVVGNREVVSSLQSISSAGRIPNMLFYGPPGTGKTTSIRAIANNLP----R 62
Query: 73 QAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAGKHKIIILDEADSMTSGAQQALRRTME 132
+VLELNASD+RGI VR IK FA + K++ILDEAD M+ AQ ALRR +E
Sbjct: 63 TSVLELNASDERGIATVRETIKEFASTY----SKTMKLVILDEADMMSRDAQNALRRIIE 118
Query: 133 LYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLE 192
+S TRF N KII P+ SRC R+ + D + R+ EI K E ++YT +G++
Sbjct: 119 DFSANTRFCLIANHLRKIISPILSRCTKFRFGPIGDTE--NRIEEICKRESIKYTPEGIK 176
Query: 193 AIIFTAEGDMRQAINNLQSTVAGFGLVNGENV 224
A+ + GDMR+A+N++Q A G V+ NV
Sbjct: 177 AVSRISMGDMRKAVNDIQGISASLGQVDESNV 208
>7293390 [L] KOG0989 Replication factor C subunit RFC4
Length = 288
Score = 156 bits (394), Expect = 4e-38
Identities = 95/276 (34%), Positives = 158/276 (56%), Gaps = 12/276 (4%)
Query: 45 MIISGLPGIGKTTSIHCLAHELLGDAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTL- 103
M++ G PG GKT++I + ++ GD + +LELNASD+RGI VVR +IK+F+Q +
Sbjct: 1 MLLYGPPGTGKTSTILAASRQIFGDMFKDRILELNASDERGINVVRTKIKNFSQLSASSV 60
Query: 104 -PAGK----HKIIILDEADSMTSGAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRC 158
P GK KIIILDEADSMT AQ ALRRTME S +TRF CN ++II P+ SRC
Sbjct: 61 RPDGKPCPPFKIIILDEADSMTHAAQSALRRTMEKESRSTRFCLICNYVSRIIVPITSRC 120
Query: 159 AILRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAINNLQSTVAGFG- 217
+ R+ L +++V+ RL I ++E V+ +D ++I+ + GD+R+AI LQS G
Sbjct: 121 SKFRFKALGEDKVIDRLKYICEMEGVKIEDDAYKSIVKISGGDLRRAITTLQSCYRLKGP 180
Query: 218 --LVNGENVFQ---IVDSPHPLIVKRMLLSGSLDESLQYLKELWVKGYSAVDIVITCFRV 272
++N ++F+ ++ + + SG+ + Q+++E+ YS ++
Sbjct: 181 EHIINTADLFEMSGVIPEYYLEDYLEVCRSGNYERLEQFVREIGFSAYSVGQMMEQFVEF 240
Query: 273 MKNLDEVKETVRLEMIKEIGFTHMRILEGVGTHLQL 308
+ + + + + + ++G R+ +G +LQ+
Sbjct: 241 IVHHPGLNDPQKATICDKLGECCFRLQDGGSEYLQI 276
>CE01268 [L] KOG0989 Replication factor C subunit RFC4
Length = 334
Score = 154 bits (390), Expect = 1e-37
Identities = 105/318 (33%), Positives = 165/318 (51%), Gaps = 10/318 (3%)
Query: 9 LPWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELLG 68
L W EKYRP L DI ++ V L+ ++PH++ G PG GKT++ +L
Sbjct: 15 LTWTEKYRPKTLDDIAYQDEVVTMLKGALQGRDLPHLLFYGPPGTGKTSAALAFCRQLFP 74
Query: 69 -DAYSQAVLELNASDDRGIEVVRNQIKHFAQKKC----TLPAGKHKIIILDEADSMTSGA 123
+ + VL+LNASD+RGI VVR +I+ F++ K KIIILDE D+MT A
Sbjct: 75 KNIFHDRVLDLNASDERGIAVVRQKIQSFSKSSLGHSHREDVLKLKIIILDEVDAMTREA 134
Query: 124 QQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLED 183
Q A+RR +E +S TTRF CN +++I P+ SRCA R+ L E ++RL I E
Sbjct: 135 QAAMRRVIEDFSKTTRFILICNYVSRLIPPVVSRCAKFRFKSLPAEIQVQRLRTICDAEG 194
Query: 184 VQYTNDGLEAIIFTAEGDMRQAINNLQS--TVAGFGLVNGENVFQIVDSPHPLI--VKRM 239
++D L+ ++ +EGD+R+A+ LQS + G N N + S LI V +
Sbjct: 195 TPMSDDELKQVMEYSEGDLRRAVCTLQSLAPILKSGDDNARNCYLRGSSDSLLISNVCKS 254
Query: 240 LLSGSLDESLQYLKELWVKGYSAVDIVITCFRVMKNLDEVKETVRLEMIKEIGFTHMRIL 299
+L+ + + + K++ K + V + CF+ + + D + + M K + RIL
Sbjct: 255 ILTADVPQIIALTKDI-TKSCTGVAFIRRCFQQLMDEDVINDENIGVMGKLVATCEKRIL 313
Query: 300 EGVGTHLQLSGMLAKIQK 317
+G L L +++
Sbjct: 314 DGCDLENNLLDFLLTLRE 331
>SPAPJ698.01c [L] KOG0990 Replication factor C subunit RFC5
Length = 142
Score = 120 bits (302), Expect = 2e-27
Identities = 61/121 (50%), Positives = 82/121 (67%), Gaps = 1/121 (0%)
Query: 9 LPWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELLG 68
LPWVEKYRP L+D+V ++D + L+ + +PHM+ G PG GKT++I A ++ G
Sbjct: 23 LPWVEKYRPANLEDVVSHKDIISTLEKFISSNRVPHMLFYGPPGTGKTSTILACARKIYG 82
Query: 69 DAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAGKHKIIILDEADSMTSGAQQALR 128
Y ++ELNASDDRGI+ VR QIK+FA + + A K+IILDEAD+MT AQ ALR
Sbjct: 83 PNYRNQLMELNASDDRGIDAVREQIKNFASTR-QIFASTFKMIILDEADAMTLAAQNALR 141
Query: 129 R 129
R
Sbjct: 142 R 142
>ECU02g0680 [L] KOG0989 Replication factor C subunit RFC4
Length = 283
Score = 116 bits (291), Expect = 4e-26
Identities = 90/256 (35%), Positives = 130/256 (50%), Gaps = 25/256 (9%)
Query: 11 WVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELLGDA 70
W EKYRP G E L+ + G+ P++++ G PG GKTT H LA + L
Sbjct: 3 WTEKYRPKSTDAFEGPEHLKNILRNSSGRGH-PNLLLYGPPGTGKTTFAHLLASQKL--- 58
Query: 71 YSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAGKHKIIILDEADSMTSGAQQALRRT 130
ELNASD+RGI V+R +IK +A GK K +ILDE +++TS AQ LRR
Sbjct: 59 ------ELNASDERGISVIREKIKVYAST-----LGKDKTVILDECENLTSDAQHCLRRV 107
Query: 131 MELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYTNDG 190
+E S TRF F N +KII PL+SR ++++ T+ ++L+ I E + Y +
Sbjct: 108 IE-DSVNTRFIFITNYPSKIIGPLRSRLVSVKFTP-TESKILE---NIGSKEGLGYDKEL 162
Query: 191 LEAIIFTAEGDMRQAINNLQSTVAGFGLVNGENVFQIVDSPHPLIVKRMLLSGSLDESLQ 250
I+ D+R+AIN LQ VA G E V P M ++
Sbjct: 163 YHRILKLCGNDLRRAINVLQG-VAPLGSFCIEEAVGAV----PQKTVDMFWEVDRPRVVE 217
Query: 251 YLKELWVKGYSAVDIV 266
Y++E +GYSA+ ++
Sbjct: 218 YVREFLREGYSALQLI 233
>SPAC27E2.10c [L] KOG0990 Replication factor C subunit RFC5
Length = 224
Score = 114 bits (284), Expect = 2e-25
Identities = 70/214 (32%), Positives = 113/214 (52%), Gaps = 9/214 (4%)
Query: 109 KIIILDEADSMTSGAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTD 168
K+IILDEAD+MT AQ ALRR +E Y+ RF CN NKI +QSRC R+ L
Sbjct: 4 KMIILDEADAMTLAAQNALRRVIEKYTKNVRFCIICNYINKISPAIQSRCTRFRFQPLPP 63
Query: 169 EQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAINNLQSTVAGFGLVNGENVFQIV 228
+++ K + +I+ E D A++ ++GDMR+A+N LQ+ A + ++ ++ V
Sbjct: 64 KEIEKTVDHVIQSEHCNIDPDAKMAVLRLSKGDMRKALNILQACHAAYDHIDVSAIYNCV 123
Query: 229 DSPHPLIVKRMLLSGSLDE------SLQYLKELWVKGYSAVDIVITCFRVMKNLDEVKET 282
PHP + L S DE ++ +K+ KG + DI+ F + L E+K
Sbjct: 124 GHPHPSDIDYFLKSIMNDEFVIAFNTISSIKQ--QKGLALQDILTCIFEALDEL-EIKPN 180
Query: 283 VRLEMIKEIGFTHMRILEGVGTHLQLSGMLAKIQ 316
++ ++ ++ R+ G +QLS M+A I+
Sbjct: 181 AKIFILDQLATIEHRMSFGCSEKIQLSAMIASIK 214
>CE05396 [DL] KOG2035 Replication factor C subunit RFC3
Length = 354
Score = 114 bits (284), Expect = 2e-25
Identities = 78/230 (33%), Positives = 115/230 (49%), Gaps = 38/230 (16%)
Query: 11 WVEKYRPHLLKDIVGNE------DTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAH 64
WV+KYRP KD++G + + L+ ++AD MPH++ G G GK T I CL
Sbjct: 4 WVDKYRP---KDLLGKDGVDYHIEQANHLKFLSADC-MPHLLFCGPSGAGKKTRIKCLLR 59
Query: 65 ELLGDAYSQAVLELNA-----------------------SDDRGIE---VVRNQIKHFAQ 98
EL G + L + + D GI VV++ +K AQ
Sbjct: 60 ELYGVGVEKTQLIMKSFTSPSNKKLEIQTVSSNYHIEMTPSDVGIYDRVVVQDLVKEMAQ 119
Query: 99 KKCTLPAGKH--KIIILDEADSMTSGAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQS 156
+ K+++L EADS+T AQ LRRTME Y+N + +C ++IIEPLQS
Sbjct: 120 TSQIESTSQRSFKVVVLCEADSLTRDAQHGLRRTMEKYANNCKIVLSCESLSRIIEPLQS 179
Query: 157 RCAILRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAI 206
RC I+ TDE V K L ++I+ E + L+ I+ +EG++R+AI
Sbjct: 180 RCIIINVPAPTDEDVTKVLRKVIERESFLLPENVLQKIVEKSEGNLRRAI 229
>ECU10g0780i [DL] KOG2035 Replication factor C subunit RFC3
Length = 354
Score = 106 bits (265), Expect = 4e-23
Identities = 81/303 (26%), Positives = 138/303 (44%), Gaps = 52/303 (17%)
Query: 11 WVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELLGDA 70
W+EKYRP +++G E+ L++ + +PHMI+ G G GK T + CL + L G
Sbjct: 3 WIEKYRPRSFDEMIGREEASGLLKSYTLE-TIPHMIVHGRSGHGKKTVLLCLVNHLYGSI 61
Query: 71 YSQAV-----------LELNASD-DRGIE------------VVRNQIKHFAQKKCTLPA- 105
+ +E++ + D +E V+++ IK Q K L
Sbjct: 62 PEMKIRTTEVLSGAKKIEVSYMESDEYVEISPSRYGYHDRAVIQSIIKEMGQTKPILSML 121
Query: 106 -----GKHKIIILDEADSMTSGAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAI 160
K++++ A+ +T AQ ALRRT+E+YS R CN+ +++IEP++SRC
Sbjct: 122 ARSRRAPIKLVVITSAEELTLEAQAALRRTIEVYSGVLRVVLVCNELSRLIEPIRSRCFF 181
Query: 161 LRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAINNLQSTVAGFGLVN 220
LR +DE V + I++ E+ + L I + GDMR+A+ L+ + F +
Sbjct: 182 LRIPGFSDEDVTSNMCRILEKENYTVPKETLVEICRESGGDMRRALCVLE--LVCFNMNE 239
Query: 221 GENVFQIVDSPHPLIVKRMLLSGSLDESLQYLKELWVKGYSAVDIVITCFRVMKNLDEVK 280
E KR + G + LK W ++ V+ C + L E++
Sbjct: 240 SE-------------AKRAKIGG------RDLKLEWELAVMSIAGVVKCNQTSSGLVEIR 280
Query: 281 ETV 283
+T+
Sbjct: 281 KTL 283
>At5g27740 [DL] KOG2035 Replication factor C subunit RFC3
Length = 354
Score = 106 bits (265), Expect = 4e-23
Identities = 70/232 (30%), Positives = 119/232 (51%), Gaps = 31/232 (13%)
Query: 11 WVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELLG-- 68
WV+KYRP L ++ +ED Q+L+ + ++ + PH++ G G GK T I L ++ G
Sbjct: 3 WVDKYRPKSLDKVIVHEDIAQKLKKLVSEQDCPHLLFYGPSGSGKKTLIMALLKQIYGAS 62
Query: 69 -------------DAYSQAV-LELNA----------SDDRGIE---VVRNQIKHFAQKKC 101
DA S+ + LEL D G + +V+ IK A+ +
Sbjct: 63 AEKVKVENRAWKVDAGSRTIDLELTTLSSTNHVELTPSDAGFQDRYIVQEIIKEMAKNRP 122
Query: 102 TLPAGK--HKIIILDEADSMTSGAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCA 159
GK +K+++L+E D ++ AQ +LRRTME YS++ R CN S+K+ E ++SRC
Sbjct: 123 IDTKGKKGYKVLVLNEVDKLSREAQHSLRRTMEKYSSSCRLILCCNSSSKVTEAIKSRCL 182
Query: 160 ILRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAINNLQS 211
+R + + E+++K L + K E +Q I + +R+AI +L++
Sbjct: 183 NVRINAPSQEEIVKVLEFVAKKESLQLPQGFAARIAEKSNRSLRRAILSLET 234
>ECU05g1530 [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 568
Score = 100 bits (248), Expect = 4e-21
Identities = 89/321 (27%), Positives = 145/321 (44%), Gaps = 38/321 (11%)
Query: 11 WVEKYRPHLLKDIVGNEDTVQRLQT-IAADGNMPHMIISGLPGIGKTTSIHCLAHELLGD 69
W EKYRP +IVGN+ V++L+ + +++SG PGIGKTT+ H + L
Sbjct: 113 WSEKYRPSKRDEIVGNQGIVKQLEDYLQGRTKYKAVLLSGQPGIGKTTTAHVVCKSL--- 169
Query: 70 AYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAG--KHKIIILDEADSMTSGAQQAL 127
V+E NASD R + N++K F + L G K K++I+DE D M+S
Sbjct: 170 --GLNVIEFNASDVRSKLEISNKVKAFVSSQSILRPGSSKSKVLIMDEVDGMSSDRGGIP 227
Query: 128 RRTMELYSNTTRFAFACN-QSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQY 186
+ CN ++N I L S C LR+ K Q+L R+ +I+ +E +
Sbjct: 228 ELISIVKETVVPIICICNDRNNPKIRTLSSYCLDLRFRKPDARQILSRVKQILDMEGKKI 287
Query: 187 TNDGLEAIIFTAEGDMRQAINNLQSTV--------AGFGLVNGENVFQIVDSPHPLIVKR 238
+ L II GD+R I+ +QS LV V + D + +R
Sbjct: 288 PDGLLNEIISRGAGDIRYTISMVQSIALRKALNLKVAENLVRKNVVKNVFDVAGEVFQRR 347
Query: 239 MLLSGSLDESLQYLKELWVKGYSAV------DIVITCFRVMKNLDEVKETVRLEMIKEIG 292
S+ E + +L+ + YS + +I+ T FR ++L E +++ L + E
Sbjct: 348 -----SISEKI----DLYFEDYSLIPLFVSENILKTSFRSARDLSECFDSISLGDVVE-- 396
Query: 293 FTHMRILEGVGTHLQLSGMLA 313
+++ GV L+ + A
Sbjct: 397 ----KLIRGVSQDWSLAPLHA 413
>Hs4506489 [DL] KOG2035 Replication factor C subunit RFC3
Length = 356
Score = 95.5 bits (236), Expect = 9e-20
Identities = 62/200 (31%), Positives = 95/200 (47%), Gaps = 28/200 (14%)
Query: 11 WVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELLGDA 70
WV+KYRP L + +++ +L+ + G+ PH+++ G G GK T I C+ EL G
Sbjct: 4 WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63
Query: 71 Y------------------------SQAVLELNASDDRGIE--VVRNQIKHFAQKKC--T 102
S LE+N SD + V++ +K AQ + T
Sbjct: 64 VEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLET 123
Query: 103 LPAGKHKIIILDEADSMTSGAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILR 162
K+++L E D +T AQ ALRRTME Y +T R CN ++K+I P++SRC +R
Sbjct: 124 NSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVR 183
Query: 163 YSKLTDEQVLKRLLEIIKLE 182
+ E + L + K E
Sbjct: 184 VPAPSIEDICHVLSTVCKKE 203
>YBR087w [DL] KOG2035 Replication factor C subunit RFC3
Length = 354
Score = 94.7 bits (234), Expect = 2e-19
Identities = 70/237 (29%), Positives = 115/237 (47%), Gaps = 37/237 (15%)
Query: 11 WVEKYRPHLLKDIVGNEDTVQRLQTIAADG-NMPHMIISGLPGIGKTTSIHCLAHELLGD 69
WV+KYRP L + NE+ L++++ ++PH+++ G G GK T L + G
Sbjct: 4 WVDKYRPKSLNALSHNEELTNFLKSLSDQPRDLPHLLLYGPNGTGKKTRCMALLESIFGP 63
Query: 70 AY-------------SQAVLELNA---------------SDDRGI------EVVRNQIKH 95
S LELN ++DR + EV + +
Sbjct: 64 GVYRLKIDVRQFVTASNRKLELNVVSSPYHLEITPSDMGNNDRIVIQELLKEVAQMEQVD 123
Query: 96 FAQKKCTLPAGKHKIIILDEADSMTSGAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQ 155
F K L A ++K +I++EA+S+T AQ ALRRTME YS R C+ + II P++
Sbjct: 124 FQDSKDGL-AHRYKCVIINEANSLTKDAQAALRRTMEKYSKNIRLIMVCDSMSPIIAPIK 182
Query: 156 SRCAILRYSKLTDEQVLKRLLEIIKLEDVQY-TNDGLEAIIFTAEGDMRQAINNLQS 211
SRC ++R +D ++ L +++ E +Q T D L+ I + G++R ++ L+S
Sbjct: 183 SRCLLIRCPAPSDSEISTILSDVVTNERIQLETKDILKRIAQASNGNLRVSLLMLES 239
>SPBC83.14c [DL] KOG2035 Replication factor C subunit RFC3
Length = 358
Score = 93.6 bits (231), Expect = 3e-19
Identities = 63/232 (27%), Positives = 116/232 (49%), Gaps = 28/232 (12%)
Query: 11 WVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHMIISGLPGIGKTTSIHCLAHELLGDA 70
W+++YRP L + ++ +RL ++++ PH+++ G G GK T + + EL G
Sbjct: 3 WLDQYRPKTLASLDYHKQLSERLISLSSTNEFPHLLVYGPSGAGKKTRVVAILRELYGPG 62
Query: 71 YSQAV------------------------LELNASDDRGIE--VVRNQIKHFAQK-KCTL 103
+ LE+ SD + +++ +K AQ + L
Sbjct: 63 SEKLKIDQRTFLTPSSKKLQINIVSSLHHLEITPSDVGNYDRVIMQELLKDVAQSAQVDL 122
Query: 104 PAGK-HKIIILDEADSMTSGAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILR 162
A K K+++++ AD +T AQ ALRRTME YSN R N ++KIIEP++SR ++R
Sbjct: 123 QAKKIFKVVVINVADELTRDAQAALRRTMEKYSNNIRLILIANSTSKIIEPIRSRTLMVR 182
Query: 163 YSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAINNLQSTVA 214
+ T E+++ + +I+ + ++ + L I + ++R+AI L++ A
Sbjct: 183 VAAPTPEEIILVMSKILTAQGLEAPDSLLNNIANNCDRNLRKAILLLETVHA 234
>YOR217w [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 861
Score = 83.2 bits (204), Expect = 5e-16
Identities = 66/247 (26%), Positives = 108/247 (43%), Gaps = 35/247 (14%)
Query: 11 WVEKYRPHLLKDIVGNEDTVQRLQTIAAD-----------------GNMPHMIISGLPGI 53
W KY P L+ + GN+ +V +L+ A+ G ++ G PGI
Sbjct: 298 WTVKYAPTNLQQVCGNKGSVMKLKNWLANWENSKKNSFKHAGKDGSGVFRAAMLYGPPGI 357
Query: 54 GKTTSIHCLAHELLGDAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPA-------- 105
GKTT+ H +A EL D +LE NASD R ++ +K+ +
Sbjct: 358 GKTTAAHLVAQELGYD-----ILEQNASDVRSKTLLNAGVKNALDNMSVVGYFKHNEEAQ 412
Query: 106 ---GKHKIIILDEADSMTSGAQQALRRTMELYSNT-TRFAFACNQSN-KIIEPLQSRCAI 160
GKH +II+DE D M+ G + + + + T T CN+ N + P C
Sbjct: 413 NLNGKHFVIIMDEVDGMSGGDRGGVGQLAQFCRKTSTPLILICNERNLPKMRPFDRVCLD 472
Query: 161 LRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAINNLQSTVAGFGLVN 220
+++ + + RL+ I E + + ++ +I T GD+RQ IN L + +N
Sbjct: 473 IQFRRPDANSIKSRLMTIAIREKFKLDPNVIDRLIQTTRGDIRQVINLLSTISTTTKTIN 532
Query: 221 GENVFQI 227
EN+ +I
Sbjct: 533 HENINEI 539
>SPBC23E6.07c [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 934
Score = 79.0 bits (193), Expect = 9e-15
Identities = 67/258 (25%), Positives = 113/258 (42%), Gaps = 35/258 (13%)
Query: 11 WVEKYRPHLLKDIVGNEDTVQRLQTIAAD-----------------GNMPHMIISGLPGI 53
W KY P LKDI GN+ VQ+LQ D G +++SG PGI
Sbjct: 361 WTSKYAPTSLKDICGNKGVVQKLQKWLQDYHKNRKSNFNKPGPDGLGLYKAVLLSGPPGI 420
Query: 54 GKTTSIHCLAHELLGDAYSQAVLELNASDDRGIEVVRNQI----------KHFAQKKCTL 103
GKTT+ H L+ VLELNASD R ++ Q+ +F K +
Sbjct: 421 GKTTAAH-----LVAKLEGYDVLELNASDTRSKRLLDEQLFGVTDSQSLAGYFGTKANPV 475
Query: 104 PAGKHK-IIILDEADSMTSGAQQAL-RRTMELYSNTTRFAFACN-QSNKIIEPLQSRCAI 160
K + ++I+DE D M+SG + + + M + + CN +++ + PL
Sbjct: 476 DMAKSRLVLIMDEIDGMSSGDRGGVGQLNMIIKKSMIPIICICNDRAHPKLRPLDRTTFD 535
Query: 161 LRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAINNLQSTVAGFGLVN 220
LR+ + + R++ I E ++ + ++ ++ + DMRQ IN L + +
Sbjct: 536 LRFRRPDANSMRSRIMSIAYREGLKLSPQAVDQLVQGTQSDMRQIINLLSTYKLSCSEMT 595
Query: 221 GENVFQIVDSPHPLIVKR 238
+N ++ + IV +
Sbjct: 596 PQNSQAVIKNSEKHIVMK 613
>7297827 [DL] KOG2035 Replication factor C subunit RFC3
Length = 318
Score = 68.9 bits (167), Expect = 9e-12
Identities = 56/193 (29%), Positives = 89/193 (46%), Gaps = 32/193 (16%)
Query: 49 GLPGIGKTTSIHCLAHELLGDAY------------------------SQAVLELNASD-- 82
G G GK T I CL E+ G S LE+N SD
Sbjct: 4 GPSGAGKKTRIMCLLREMYGSGVERLRSETMTFTTPSNRKVEVMTVSSNYHLEVNPSDAG 63
Query: 83 --DRGIEVVRNQIKHFAQKKCTLPAGKH--KIIILDEADSMTSGAQQALRRTMELYSNTT 138
DR VV + IK AQ +G+ K+I++ E D +T AQ ALRRTME Y T
Sbjct: 64 MYDR--TVVIDLIKQVAQTHQIEISGQREFKVIVISEGDELTKDAQHALRRTMEKYVATC 121
Query: 139 RFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTA 198
R + N +++II ++SRC +R + + +++ L K E + + + ++ +
Sbjct: 122 RIIISVNSTSRIIPAIRSRCLGIRVAAPNETEIVSILQNTCKREGLALPVELAKRVVDKS 181
Query: 199 EGDMRQAINNLQS 211
E ++R+A+ L++
Sbjct: 182 ERNLRRALLMLEA 194
>SPBC902.02c [DL] KOG1969 DNA replication checkpoint protein CHL12/CTF18
Length = 960
Score = 68.2 bits (165), Expect = 2e-11
Identities = 60/252 (23%), Positives = 97/252 (37%), Gaps = 58/252 (23%)
Query: 11 WVEKYRPHLLKDIVGNEDTVQ-----------------------------RLQTIAADGN 41
WV+ YRP L +D++G+E + R I +D +
Sbjct: 353 WVDTYRPQLFRDLLGDERVHRAAMHWIKAWDPCVFGKSRLQPSKSMRFNPRFTNITSDSD 412
Query: 42 MPH---MIISGLPGIGKTTSIHCLAHELLGDAYSQAVLELNASDDRGIEVVRNQIKHFAQ 98
P M+++GL G GKTT H +AH+ VLE+NASDDR V ++
Sbjct: 413 RPDKRIMMLTGLAGAGKTTLAHVIAHQA-----GYKVLEINASDDRTAHTVHEKVSSAIS 467
Query: 99 KKCTLPAGKHKIIILDEADSMTSGAQQALRRTMELYSNTTRFAFACNQSNK--------- 149
L + + +I+DE D +AL +E T ++ A N K
Sbjct: 468 NHSAL-SSQPTCVIVDEIDGGDPAFVRALLSLLESDEKATEYSQAGNSKKKKKFKKLCRP 526
Query: 150 -----------IIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTA 198
+ PL+ I+ + ++ RL I + E++ + L +
Sbjct: 527 IICICNDLYTPALRPLRPYAQIIYFRPPPQASLVGRLRTICRNENIAVDSRSLTLLTDIY 586
Query: 199 EGDMRQAINNLQ 210
D+R IN+LQ
Sbjct: 587 NSDIRSCINSLQ 598
>At1g14460 [L] KOG0989 Replication factor C subunit RFC4
Length = 1102
Score = 68.2 bits (165), Expect = 2e-11
Identities = 68/274 (24%), Positives = 120/274 (42%), Gaps = 39/274 (14%)
Query: 13 EKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHM-IISGLPGIGKTTSIHCLAHELLGDAY 71
+KY+P +++G VQ L G + H+ + G G GKT++ L+ L D
Sbjct: 426 QKYKPMFFDELIGQSIVVQSLMNAVKKGRVAHVYLFQGPRGTGKTSTARILSAALNCDVV 485
Query: 72 --------------------SQAVLELNASDDRGIEVVRNQIKHFAQKKCTLP---AGKH 108
S+ +LEL+A G E VR +K K TL + ++
Sbjct: 486 TEEMKPCGYCKECSDYMLGKSRDLLELDAGKKNGAEKVRYLLK----KLLTLAPQSSQRY 541
Query: 109 KIIILDEADSMTSGAQQALRRTMELYSNTTRFAFAC--NQSNKIIEPLQSRCAILRYSKL 166
K+ ++DE + S +L + +E + +F F C + + +QSRC ++K+
Sbjct: 542 KVFVIDECHLLPSRTWLSLLKFLE--NPLQKFVFVCITTDLDNVPRTIQSRCQKYIFNKV 599
Query: 167 TDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAINNL-QSTVAG----FGLVNG 221
D ++ RL +I E++ + L+ I A+G +R A L Q ++ G LVN
Sbjct: 600 RDGDIVVRLRKIASDENLDVESQALDLIALNADGSLRDAETMLEQLSLMGKRITVDLVN- 658
Query: 222 ENVFQIVDSPHPLIVKRMLLSGSLDESLQYLKEL 255
+ +V L + + LS E+++ +EL
Sbjct: 659 -ELVGVVSDDKLLELLELALSSDTAETVKKAREL 691
>CE20613 [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 839
Score = 67.0 bits (162), Expect = 3e-11
Identities = 61/253 (24%), Positives = 104/253 (40%), Gaps = 49/253 (19%)
Query: 9 LPWVEKYRPHLLKDIVGNEDTVQRLQTI----------------------------AADG 40
L WV+KY+P + ++VG + + + DG
Sbjct: 278 LSWVDKYKPKRMGELVGQNGDKSPINKLLEWIKDWAKHNLGEGAKIKKPKPAPWMSSQDG 337
Query: 41 -NMPHMIISGLPGIGKTTSIHCLAHELLGDAYSQAVLELNASDDRGIEVVRNQI------ 93
+ ++SG PG+GKTT + +L ++E+NASD R + + +I
Sbjct: 338 TSFKAALLSGSPGVGKTTCAYMACQQL-----GLQLVEMNASDVRSKKHLEAKIGELSGS 392
Query: 94 ----KHFAQKKCTLPAGK--HKIIILDEADSMTSGAQQALRRTMELYSNTTRFAFAC--- 144
+ F KKC + H I+I+DE D M+ +A + ++ C
Sbjct: 393 HQIEQFFGAKKCAPQDNQKVHHILIMDEVDGMSGNEDRAGISELIQIIKESKIPIICICN 452
Query: 145 NQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQ 204
++ + I L + C LR+ K E + R++ I E ++ + L+ II + D+RQ
Sbjct: 453 DRQHPKIRTLANYCYDLRFPKPRVETIRSRMMTICSQEKMKIGKEELDEIIELSGHDVRQ 512
Query: 205 AINNLQSTVAGFG 217
I NLQ G G
Sbjct: 513 TIYNLQMRSKGVG 525
>7296805 [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 986
Score = 65.9 bits (159), Expect = 8e-11
Identities = 55/238 (23%), Positives = 100/238 (41%), Gaps = 42/238 (17%)
Query: 9 LPWVEKYRPHLLKDIVGNEDTVQRLQTIAA---------DGNMPHM-------------- 45
+ WV+K++P +K+IVG + + DGN
Sbjct: 421 MAWVDKHKPTSIKEIVGQAGAASNVTKLMNWLSKWYVNHDGNKKPQRPNPWAKNDDGSFY 480
Query: 46 ---IISGLPGIGKTTSIHCLAHELLGDAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCT 102
++SG PGIGKTT+ + EL DA +E NASD R ++++++ K
Sbjct: 481 KAALLSGPPGIGKTTTATLVVKELGFDA-----VEFNASDTRSKRLLKDEVSTLLSNKSL 535
Query: 103 L--------PAGKHKIIILDEADSMTSGAQQALRRTMELYSNTTRFAFAC---NQSNKII 151
+ ++I+DE D M + + + + C ++++ I
Sbjct: 536 SGYFTGQGQAVSRKHVLIMDEVDGMAGNEDRGGMQELIALIKDSSIPIICMCNDRNHPKI 595
Query: 152 EPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAINNL 209
L + C LR+ + EQ+ +++ I E V+ + +E II D+RQ+IN++
Sbjct: 596 RSLVNYCYDLRFQRPRLEQIKGKIMSICFKEKVKISPAKVEEIIAATNNDIRQSINHI 653
>Hs22045214 [L] KOG0991 Replication factor C subunit RFC2
Length = 144
Score = 62.4 bits (150), Expect = 8e-10
Identities = 40/129 (31%), Positives = 63/129 (48%), Gaps = 26/129 (20%)
Query: 149 KIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAINN 208
K+ E S+C +LRY+KLTD + R + + V YT+ GLEAII A
Sbjct: 33 KLHEATGSQCIVLRYTKLTDARTSVRPMNAREKGTVLYTDFGLEAIILMA---------- 82
Query: 209 LQSTVAGFGLVNGENVFQIVDSPHPLIVKRML---LSGSLDESLQYLKELWVKGYSAVDI 265
++F++ D PHPL++K M+ ++ + E+ + LW GYS D+
Sbjct: 83 -------------RSMFRVCDEPHPLLMKEMIQHCVNAHVKETYKIPAHLWHLGYSPEDV 129
Query: 266 VITCFRVMK 274
+ F+V K
Sbjct: 130 IGNIFQVCK 138
>At2g02480 [L] KOG0989 Replication factor C subunit RFC4
Length = 1153
Score = 62.0 bits (149), Expect = 1e-09
Identities = 60/268 (22%), Positives = 112/268 (41%), Gaps = 28/268 (10%)
Query: 13 EKYRPHLLKDIVGNEDTVQRLQTIAADGNM-PHMIISGLPGIGKTTS-------IHCLAH 64
+KYRP ++++G VQ L + P + G G GKT++ ++C+A
Sbjct: 453 QKYRPMFFEELIGQSIVVQSLMNAVKRSRIAPVYLFQGPRGTGKTSTARIFSAALNCVAT 512
Query: 65 ELLG------------DAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLP--AGKHKI 110
E + S+ EL+ ++ +G + VR +K+ LP + +K+
Sbjct: 513 EEMKPCGYCKECNDFMSGKSKDFWELDGANKKGADKVRYLLKNLPT---ILPRNSSMYKV 569
Query: 111 IILDEADSMTSGAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQ 170
++DE + S + + +E F F + +QSRC + KL D
Sbjct: 570 FVIDECHLLPSKTWLSFLKFLENPLQKVVFIFITTDLENVPRTIQSRCQKFLFDKLKDSD 629
Query: 171 VLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAINNL-QSTVAGFGLVNG--ENVFQI 227
++ RL +I E++ L+ I A+G +R A L Q ++ G + + +
Sbjct: 630 IVVRLKKIASDENLDVDLHALDLIAMNADGSLRDAETMLEQLSLLGKRITTALVNELVGV 689
Query: 228 VDSPHPLIVKRMLLSGSLDESLQYLKEL 255
V L + + LS E+++ +EL
Sbjct: 690 VSDEKLLELLELALSSDTAETVKRAREL 717
>Hs15011931 [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 1148
Score = 58.5 bits (140), Expect = 1e-08
Identities = 57/240 (23%), Positives = 97/240 (39%), Gaps = 44/240 (18%)
Query: 9 LPWVEKYRPHLLKDIVGNEDT----------VQRLQTIAAD-----------------GN 41
L WV+KY+P LK I+G + ++ Q +++ +
Sbjct: 584 LLWVDKYKPTSLKTIIGQQGDQSCANKLLRWLRNWQKSSSEDKKHAAKFGKFSGKDDGSS 643
Query: 42 MPHMIISGLPGIGKTTSIHCLAHELLGDAYSQAVLELNASDDRGIEVVR---------NQ 92
++SG PG+GKTT+ + EL G +Y +ELNASD R ++
Sbjct: 644 FKAALLSGPPGVGKTTTASLVCQEL-GYSY----VELNASDTRSKSSLKAIVAESLNNTS 698
Query: 93 IKHFAQKKCTLPAGKHKIIILDEADSMTSGAQQALRRTMELYSNTTRFAFAC---NQSNK 149
IK F +I+DE D M + + + T+ C ++++
Sbjct: 699 IKGFYSNGAASSVSTKHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHP 758
Query: 150 IIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAINNL 209
I L C LR+ + EQ+ ++ I E ++ + II A D+RQ ++NL
Sbjct: 759 KIRSLVHYCFDLRFQRPRVEQIKGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNL 818
>At1g24290 [L] KOG2028 ATPase related to the helicase subunit of the Holliday
junction resolvase
Length = 525
Score = 57.0 bits (136), Expect = 4e-08
Identities = 53/213 (24%), Positives = 96/213 (44%), Gaps = 19/213 (8%)
Query: 10 PWVEKYRPHLLKDIVGNEDTVQR---LQTIAADGNMPHMIISGLPGIGKTTSIHCLAHEL 66
P E+ RP L D+VG + + L++ +P ++ G PG GKT+ +A L
Sbjct: 102 PLSERMRPRTLDDVVGQDHLLSPSSLLRSAVESNRLPSIVFWGPPGTGKTS----IAKSL 157
Query: 67 LGDAYSQAV---LELNASDDRGIEVVRNQIKHFAQKKCTLPAGKHKIIILDEADSMTSGA 123
+ + ++ + L+A G++ VR+ ++ + K+ L K ++ +DE
Sbjct: 158 INSSKDPSLYRFVSLSAVTS-GVKDVRDAVE--SAKRLNLEGRKRTVLFMDEVHRFNKSQ 214
Query: 124 QQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTD---EQVLKRLLEIIK 180
Q +E S A N S +I PL SRC +L + L E +L+R ++ +
Sbjct: 215 QDTFLPVIEDGSILFIGATTENPSFHLITPLLSRCRVLTLNPLKPNHVETLLRRAVDDSE 274
Query: 181 L---EDVQYTNDGLEAIIFTAEGDMRQAINNLQ 210
V+ + +E + +GD R A+N L+
Sbjct: 275 RGLPNSVEVDDSVIEFLANNCDGDARVALNALE 307
>Hs14777079 [DL] KOG1969 DNA replication checkpoint protein CHL12/CTF18
Length = 1003
Score = 54.7 bits (130), Expect = 2e-07
Identities = 50/192 (26%), Positives = 79/192 (41%), Gaps = 32/192 (16%)
Query: 46 IISGLPGIGKTTSIHCLAHELLGDAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPA 105
++ G PG+GKTT H +A +V+E+NASDDR EV R +I+ Q + L A
Sbjct: 399 LLCGPPGLGKTTLAHVIARHA-----GYSVVEMNASDDRSPEVFRTRIEAATQMESVLGA 453
Query: 106 -GKHKIIILDEADSMTSGAQQAL-------------------------RRTMELYSNTTR 139
GK +++DE D A L RR E
Sbjct: 454 GGKPNCLVIDEIDGAPVAAINVLLSILNRKGPQEVGPQGPAVPSGGGRRRRAEGGLLMRP 513
Query: 140 FAFACN-QSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTA 198
CN Q + L+ + +L + ++++RL E+ + ++ L A+
Sbjct: 514 IICICNDQFAPSLRQLKQQAFLLHFPPTLPSRLVQRLQEVSLRQGMRADPGVLAALCEKT 573
Query: 199 EGDMRQAINNLQ 210
+ D+R IN LQ
Sbjct: 574 DNDIRACINTLQ 585
>Hs18426902 [L] KOG2028 ATPase related to the helicase subunit of the Holliday
junction resolvase
Length = 665
Score = 52.0 bits (123), Expect = 1e-06
Identities = 54/231 (23%), Positives = 93/231 (39%), Gaps = 32/231 (13%)
Query: 10 PWVEKYRPHLLKDIVGNEDTVQR---LQTIAADGNMPHMIISGLPGIGKTTSIHCLAHEL 66
P + RP L+D G V + L+++ +P +I+ G PG GKTT H +A
Sbjct: 226 PLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKTTLAHIIASN- 284
Query: 67 LGDAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAGKHKIIILDEADSMTSGAQQA 126
+S + L+A++ + + VR+ IK +K + I+ +DE Q
Sbjct: 285 -SKKHSIRFVTLSATNAKTND-VRDVIKQAQNEKSFFK--RKTILFIDEIHRFNKSQQDT 340
Query: 127 LRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEII------- 179
+E + T A N S ++ L SRC ++ KL E ++ L+ I
Sbjct: 341 FLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHV 400
Query: 180 ----------------KLEDVQYTND-GLEAIIFTAEGDMRQAINNLQSTV 213
E + D ++ + + ++GD R +N LQ V
Sbjct: 401 LDSSRPTDPLSHSSNSSSEPAMFIEDKAVDTLAYLSDGDARAGLNGLQLAV 451
>At5g45720 [L] KOG0989 Replication factor C subunit RFC4
Length = 900
Score = 52.0 bits (123), Expect = 1e-06
Identities = 45/226 (19%), Positives = 87/226 (37%), Gaps = 26/226 (11%)
Query: 5 TKLELPWVEKYRPHLLKDIVGNEDTVQRLQTIAADGNMPHM-IISGLPGIGKTTSIHCLA 63
T+ + +KY P +D++G VQ L A + + + G G GKT+ A
Sbjct: 339 TRWHQSFTQKYAPRTFRDLLGQNLVVQALSNAIAKRRVGLLYVFHGPNGTGKTSCARVFA 398
Query: 64 HEL-------------------LGDAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLP 104
L D ++ + E+ E + ++ Q+K L
Sbjct: 399 RALNCHSTEQSKPCGVCSSCVSYDDGKNRYIREMGPVKSFDFENLLDKTNIRQQQKQQL- 457
Query: 105 AGKHKIIILDEADSMTSGAQQALRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYS 164
++I D+ D+M++ L + ++ F C+ + + + SRC +
Sbjct: 458 -----VLIFDDCDTMSTDCWNTLSKIVDRAPRRVVFVLVCSSLDVLPHIIVSRCQKFFFP 512
Query: 165 KLTDEQVLKRLLEIIKLEDVQYTNDGLEAIIFTAEGDMRQAINNLQ 210
KL D ++ L I E++ D L+ + ++G +R A L+
Sbjct: 513 KLKDVDIIDSLQLIASKEEIDIDKDALKLVASRSDGSLRDAEMTLE 558
>SPAC26H5.02c [L] KOG2028 ATPase related to the helicase subunit of the Holliday
junction resolvase
Length = 497
Score = 48.9 bits (115), Expect = 1e-05
Identities = 55/214 (25%), Positives = 82/214 (37%), Gaps = 18/214 (8%)
Query: 10 PWVEKYRPHLLKDIVGNEDTVQR---LQTIAADGNMPHMIISGLPGIGKTTSIHCLAHEL 66
P E+ RP L + VG E+ V ++ + MI+ G G GKTT +A
Sbjct: 85 PLAERARPKSLDEYVGQEELVGERGIIRNLIEQDRCNSMILWGSAGTGKTTLARLIAVTT 144
Query: 67 LGDAYSQAVLELNASDDRGIEVVRNQIKHFAQKKCTLPAGKHKIIILDEADSMTSGAQQA 126
+ +D R +I +Q TL G+ II LDE Q
Sbjct: 145 KSRFIEISATSTTVADCR-------KIFEDSQNYLTL-TGRKTIIFLDEVHRFNRAQQDI 196
Query: 127 LRRTMELYSNTTRFAFACNQSNKIIEPLQSRCAILRYSKLTDEQVLKRLLEIIKLEDVQY 186
+E T A N S ++ L SRC + KLT + V K L LE +
Sbjct: 197 FLPMVEKGLVTLIGATTENPSFRLNSALISRCPVFVLKKLTRDNVKKILNHACLLESERL 256
Query: 187 TNDG-------LEAIIFTAEGDMRQAINNLQSTV 213
+ ++ I +GD R A+N L+ ++
Sbjct: 257 GSSMPNVETSIIDYISAITDGDARMALNALEMSI 290
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.136 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,802,475
Number of Sequences: 60738
Number of extensions: 721359
Number of successful extensions: 2557
Number of sequences better than 1.0e-05: 44
Number of HSP's better than 0.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2443
Number of HSP's gapped (non-prelim): 49
length of query: 320
length of database: 30,389,216
effective HSP length: 106
effective length of query: 214
effective length of database: 23,950,988
effective search space: 5125511432
effective search space used: 5125511432
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)