ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1002 check: MH D KOG0596 Cell cycle control, cell division, chromosome partitioning Dual specificity; serine/threonine and tyrosine kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1002 349187 351565 793
(793 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL028c [D] KOG0596 Dual specificity; serine/threonine and tyros... 525 e-148
Hs4507719 [D] KOG0596 Dual specificity; serine/threonine and tyr... 191 3e-48
Hs20547712 [D] KOG0596 Dual specificity; serine/threonine and ty... 191 3e-48
At1g77720 [D] KOG0596 Dual specificity; serine/threonine and tyr... 177 4e-44
ECU02g0510 [D] KOG0596 Dual specificity; serine/threonine and ty... 159 2e-38
7300288 [D] KOG0596 Dual specificity; serine/threonine and tyros... 141 3e-33
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 97 7e-20
At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protei... 96 3e-19
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 95 4e-19
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 95 4e-19
YHR102w [T] KOG0201 Serine/threonine protein kinase 94 8e-19
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 94 1e-18
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 94 1e-18
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 93 1e-18
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 92 2e-18
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 92 4e-18
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 91 7e-18
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 90 1e-17
CE18454 [T] KOG4717 Serine/threonine protein kinase 90 2e-17
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 2e-17
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 89 3e-17
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 89 3e-17
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 89 3e-17
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 89 3e-17
7303211 [T] KOG4717 Serine/threonine protein kinase 88 4e-17
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 88 4e-17
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 88 6e-17
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 87 8e-17
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 87 8e-17
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 87 8e-17
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 87 8e-17
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 87 8e-17
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 87 1e-16
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 87 1e-16
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 87 1e-16
CE28479 [T] KOG0583 Serine/threonine protein kinase 87 1e-16
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 87 1e-16
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 87 1e-16
At3g23000 [T] KOG0583 Serine/threonine protein kinase 87 1e-16
YDR507c [D] KOG0588 Serine/threonine protein kinase 86 2e-16
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 86 2e-16
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 86 3e-16
7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 85 4e-16
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 85 5e-16
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 84 6e-16
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 84 8e-16
YDR477w [T] KOG0583 Serine/threonine protein kinase 84 1e-15
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 83 1e-15
At1g01140 [T] KOG0583 Serine/threonine protein kinase 83 1e-15
At5g28290 [R] KOG0589 Serine/threonine protein kinase 83 2e-15
YLR113w [T] KOG0660 Mitogen-activated protein kinase 82 2e-15
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 82 2e-15
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 82 2e-15
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 82 2e-15
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 82 3e-15
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 82 4e-15
CE28218 [D] KOG0588 Serine/threonine protein kinase 81 5e-15
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 5e-15
CE15235 [R] KOG0589 Serine/threonine protein kinase 81 7e-15
CE00847 [T] KOG0583 Serine/threonine protein kinase 81 7e-15
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 81 7e-15
7294217 [D] KOG0588 Serine/threonine protein kinase 81 7e-15
7291043 [T] KOG0660 Mitogen-activated protein kinase 81 7e-15
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 81 7e-15
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 80 9e-15
SPCC1919.01 [T] KOG0583 Serine/threonine protein kinase 80 9e-15
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 80 9e-15
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 80 9e-15
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 80 9e-15
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 80 9e-15
CE23001 [R] KOG0589 Serine/threonine protein kinase 80 9e-15
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 80 9e-15
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 9e-15
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 80 1e-14
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 80 1e-14
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 80 1e-14
At3g04810 [R] KOG0589 Serine/threonine protein kinase 80 1e-14
YPR054w [T] KOG0660 Mitogen-activated protein kinase 80 2e-14
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 80 2e-14
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 79 2e-14
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 79 2e-14
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 79 2e-14
At5g39420 [D] KOG0600 Cdc2-related protein kinase 79 2e-14
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 79 3e-14
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 79 3e-14
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 79 4e-14
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 79 4e-14
At5g39440 [T] KOG0583 Serine/threonine protein kinase 79 4e-14
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 4e-14
At5g01820 [T] KOG0583 Serine/threonine protein kinase 79 4e-14
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 4e-14
At2g32510 [T] KOG0198 MEKK and related serine/threonine protein ... 79 4e-14
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 79 4e-14
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 78 5e-14
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 78 5e-14
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 78 5e-14
At1g71530 [D] KOG0600 Cdc2-related protein kinase 78 5e-14
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 78 6e-14
CE06762 [T] KOG0660 Mitogen-activated protein kinase 78 6e-14
At4g24400 [T] KOG0583 Serine/threonine protein kinase 78 6e-14
At4g10010 [D] KOG0600 Cdc2-related protein kinase 78 6e-14
At3g01090 [T] KOG0583 Serine/threonine protein kinase 78 6e-14
At1g54510 [R] KOG0589 Serine/threonine protein kinase 78 6e-14
At1g48260 [T] KOG0583 Serine/threonine protein kinase 78 6e-14
YGR040w [T] KOG0660 Mitogen-activated protein kinase 77 8e-14
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 77 8e-14
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 77 8e-14
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 77 8e-14
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 77 8e-14
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 77 8e-14
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 77 8e-14
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 77 8e-14
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 77 8e-14
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 77 8e-14
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 77 8e-14
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 77 8e-14
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 77 8e-14
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 77 8e-14
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 77 8e-14
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 8e-14
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 8e-14
At1g53050 [D] KOG0600 Cdc2-related protein kinase 77 8e-14
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 8e-14
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 77 1e-13
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 77 1e-13
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 77 1e-13
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 77 1e-13
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 77 1e-13
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 77 1e-13
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 77 1e-13
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 1e-13
At2g30360 [T] KOG0583 Serine/threonine protein kinase 77 1e-13
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 77 1e-13
7291742_1 [T] KOG0612 Rho-associated coiled-coil containing prot... 77 1e-13
YDR523c [T] KOG0201 Serine/threonine protein kinase 77 1e-13
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 77 1e-13
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 1e-13
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 77 1e-13
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 77 1e-13
7292656 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 77 1e-13
At4g08470 [T] KOG0198 MEKK and related serine/threonine protein ... 76 2e-13
At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 2e-13
At1g18670 [D] KOG0600 Cdc2-related protein kinase 76 2e-13
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 76 2e-13
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 76 2e-13
YCL024w [T] KOG0583 Serine/threonine protein kinase 76 2e-13
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 76 2e-13
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 76 2e-13
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 76 2e-13
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 76 2e-13
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 76 2e-13
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 76 2e-13
At5g50860 [D] KOG0600 Cdc2-related protein kinase 76 2e-13
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 2e-13
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 76 2e-13
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 75 3e-13
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 75 3e-13
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 3e-13
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 3e-13
At1g29230 [T] KOG0583 Serine/threonine protein kinase 75 3e-13
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 75 4e-13
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 75 4e-13
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 75 4e-13
At5g67080 [T] KOG0198 MEKK and related serine/threonine protein ... 75 4e-13
At5g10930 [T] KOG0583 Serine/threonine protein kinase 75 4e-13
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 4e-13
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 75 5e-13
YKL101w [D] KOG0588 Serine/threonine protein kinase 75 5e-13
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 75 5e-13
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 75 5e-13
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 75 5e-13
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 75 5e-13
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 75 5e-13
At4g30960 [T] KOG0583 Serine/threonine protein kinase 75 5e-13
At4g08480 [T] KOG0198 MEKK and related serine/threonine protein ... 75 5e-13
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 75 5e-13
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 75 5e-13
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 75 5e-13
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 75 5e-13
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 7e-13
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 74 7e-13
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 74 7e-13
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 74 7e-13
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 74 7e-13
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 74 7e-13
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 74 7e-13
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 7e-13
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 74 7e-13
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 7e-13
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 74 7e-13
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 74 7e-13
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 74 7e-13
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 74 7e-13
At3g29160 [T] KOG0583 Serine/threonine protein kinase 74 7e-13
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 7e-13
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 74 7e-13
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 74 7e-13
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 74 7e-13
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 74 9e-13
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 9e-13
At5g35410 [T] KOG0583 Serine/threonine protein kinase 74 9e-13
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 9e-13
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 9e-13
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 74 9e-13
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 74 1e-12
At5g57630 [T] KOG0583 Serine/threonine protein kinase 74 1e-12
At4g22940 [D] KOG0600 Cdc2-related protein kinase 74 1e-12
At4g14580 [T] KOG0583 Serine/threonine protein kinase 74 1e-12
At3g17510 [T] KOG0583 Serine/threonine protein kinase 74 1e-12
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 74 1e-12
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 74 1e-12
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 74 1e-12
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 73 1e-12
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 73 1e-12
Hs11140819 [T] KOG1151 Tousled-like protein kinase 73 1e-12
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 73 1e-12
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 73 1e-12
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 73 2e-12
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 73 2e-12
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 73 2e-12
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 73 2e-12
At5g40440 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 73 2e-12
At1g74330 [D] KOG0600 Cdc2-related protein kinase 73 2e-12
7299536 [D] KOG0580 Serine/threonine protein kinase 73 2e-12
7290150 [T] KOG0583 Serine/threonine protein kinase 73 2e-12
7290147 [T] KOG0583 Serine/threonine protein kinase 73 2e-12
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 72 3e-12
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 72 3e-12
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 72 3e-12
CE17284 [T] KOG0583 Serine/threonine protein kinase 72 3e-12
At5g25110 [T] KOG0583 Serine/threonine protein kinase 72 3e-12
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 72 3e-12
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 72 3e-12
7290249 [R] KOG0586 Serine/threonine protein kinase 72 3e-12
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 72 3e-12
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 72 3e-12
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 72 3e-12
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 72 3e-12
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 72 3e-12
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 72 3e-12
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 72 3e-12
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 72 3e-12
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 72 3e-12
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 3e-12
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 72 3e-12
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 3e-12
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 72 4e-12
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 72 4e-12
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 72 4e-12
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 72 4e-12
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 72 4e-12
CE26422 [D] KOG0600 Cdc2-related protein kinase 72 4e-12
At5g45820 [T] KOG0583 Serine/threonine protein kinase 72 4e-12
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 4e-12
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 4e-12
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 4e-12
At1g54610 [D] KOG0600 Cdc2-related protein kinase 72 4e-12
At1g33770 [D] KOG0600 Cdc2-related protein kinase 72 4e-12
At1g03740 [D] KOG0600 Cdc2-related protein kinase 72 4e-12
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 71 6e-12
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 71 6e-12
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 71 6e-12
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 71 6e-12
CE28674 [T] KOG0201 Serine/threonine protein kinase 71 6e-12
CE27573 [T] KOG0198 MEKK and related serine/threonine protein ki... 71 6e-12
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 71 6e-12
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 71 6e-12
CE07737 [T] KOG0198 MEKK and related serine/threonine protein ki... 71 6e-12
CE07510 [T] KOG0201 Serine/threonine protein kinase 71 6e-12
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 71 6e-12
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 71 6e-12
7302464 [R] KOG0586 Serine/threonine protein kinase 71 6e-12
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 71 6e-12
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 71 7e-12
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 71 7e-12
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 71 7e-12
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 71 7e-12
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 71 7e-12
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 71 7e-12
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 71 7e-12
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 71 7e-12
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 71 7e-12
At2g25090 [T] KOG0583 Serine/threonine protein kinase 71 7e-12
At1g30270 [T] KOG0583 Serine/threonine protein kinase 71 7e-12
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 71 7e-12
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 71 7e-12
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 70 1e-11
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 70 1e-11
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 70 1e-11
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 70 1e-11
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 70 1e-11
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 70 1e-11
CE07458 [T] KOG0583 Serine/threonine protein kinase 70 1e-11
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 70 1e-11
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 70 1e-11
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 70 1e-11
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 70 1e-11
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 1e-11
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 70 1e-11
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 70 1e-11
At3g50310 [T] KOG0198 MEKK and related serine/threonine protein ... 70 1e-11
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 1e-11
At2g38490 [T] KOG0583 Serine/threonine protein kinase 70 1e-11
7301213 [R] KOG0589 Serine/threonine protein kinase 70 1e-11
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 70 2e-11
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 70 2e-11
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 70 2e-11
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 70 2e-11
CE27768 [R] KOG0586 Serine/threonine protein kinase 70 2e-11
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 70 2e-11
CE23838 [R] KOG0586 Serine/threonine protein kinase 70 2e-11
At5g44290 [D] KOG0600 Cdc2-related protein kinase 70 2e-11
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 2e-11
At3g53640 [A] KOG0670 U4/U6-associated splicing factor PRP4 70 2e-11
At3g44200 [R] KOG0589 Serine/threonine protein kinase 70 2e-11
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 2e-11
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 70 2e-11
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 70 2e-11
7299438 [R] KOG0586 Serine/threonine protein kinase 70 2e-11
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 70 2e-11
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 69 2e-11
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 69 2e-11
YBL016w [T] KOG0660 Mitogen-activated protein kinase 69 2e-11
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 69 2e-11
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 69 2e-11
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 69 2e-11
Hs10190706 [T] KOG0671 LAMMER dual specificity kinases 69 2e-11
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 69 2e-11
At4g18700 [T] KOG0583 Serine/threonine protein kinase 69 2e-11
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 69 2e-11
At2g26980 [T] KOG0583 Serine/threonine protein kinase 69 2e-11
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 2e-11
7301719 [T] KOG0671 LAMMER dual specificity kinases 69 2e-11
7290436 [T] KOG1151 Tousled-like protein kinase 69 2e-11
7290342 [G] KOG0658 Glycogen synthase kinase-3 69 2e-11
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 69 2e-11
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 69 3e-11
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 69 3e-11
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 69 3e-11
CE28643 [T] KOG0583 Serine/threonine protein kinase 69 3e-11
At5g64960 [D] KOG0600 Cdc2-related protein kinase 69 3e-11
At5g45810 [T] KOG0583 Serine/threonine protein kinase 69 3e-11
At5g27510 [T] KOG0198 MEKK and related serine/threonine protein ... 69 3e-11
At5g20930 [T] KOG1151 Tousled-like protein kinase 69 3e-11
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 3e-11
At2g34180 [T] KOG0583 Serine/threonine protein kinase 69 3e-11
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 3e-11
At1g09600 [D] KOG0600 Cdc2-related protein kinase 69 3e-11
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 69 3e-11
Hs4502883_2 [T] KOG0671 LAMMER dual specificity kinases 69 3e-11
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 69 4e-11
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 4e-11
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 69 4e-11
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 69 4e-11
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 69 4e-11
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 69 4e-11
CE04586 [T] KOG1989 ARK protein kinase family 69 4e-11
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 69 4e-11
At5g10270 [D] KOG0600 Cdc2-related protein kinase 69 4e-11
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 69 4e-11
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 69 4e-11
7296894_1 [T] KOG1989 ARK protein kinase family 69 4e-11
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 68 5e-11
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 68 5e-11
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 68 5e-11
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 68 5e-11
7300778 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 68 5e-11
YHR030c [T] KOG0660 Mitogen-activated protein kinase 68 6e-11
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 68 6e-11
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 68 6e-11
Hs18677726 [T] KOG1151 Tousled-like protein kinase 68 6e-11
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 68 6e-11
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 68 6e-11
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 68 6e-11
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 68 6e-11
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 68 6e-11
CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 68 6e-11
CE03103 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta s... 68 6e-11
At4g32830 [D] KOG0580 Serine/threonine protein kinase 68 6e-11
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 68 6e-11
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 68 6e-11
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 67 8e-11
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 67 8e-11
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 67 8e-11
Hs17999535 [A] KOG0670 U4/U6-associated splicing factor PRP4 67 8e-11
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 67 8e-11
ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing pro... 67 8e-11
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 67 8e-11
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 67 8e-11
At5g01810 [T] KOG0583 Serine/threonine protein kinase 67 8e-11
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 8e-11
At3g15220 [T] KOG0201 Serine/threonine protein kinase 67 8e-11
At2g32850 [T] KOG1989 ARK protein kinase family 67 8e-11
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 67 1e-10
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 67 1e-10
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 67 1e-10
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 67 1e-10
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 67 1e-10
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 67 1e-10
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 67 1e-10
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 67 1e-10
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 67 1e-10
7293601 [T] KOG0577 Serine/threonine protein kinase 67 1e-10
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 67 1e-10
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 67 1e-10
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 67 1e-10
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 67 1e-10
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 67 1e-10
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 67 1e-10
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 67 1e-10
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 67 1e-10
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 67 1e-10
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 67 1e-10
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 67 1e-10
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 67 1e-10
7291932 [A] KOG0670 U4/U6-associated splicing factor PRP4 67 1e-10
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 66 2e-10
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 66 2e-10
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 66 2e-10
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 66 2e-10
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 66 2e-10
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 66 2e-10
CE29092 [T] KOG0694 Serine/threonine protein kinase 66 2e-10
CE23524 [T] KOG1151 Tousled-like protein kinase 66 2e-10
CE21401 [G] KOG0658 Glycogen synthase kinase-3 66 2e-10
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 66 2e-10
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 66 2e-10
At2g25880 [D] KOG0580 Serine/threonine protein kinase 66 2e-10
7300224 [T] KOG0201 Serine/threonine protein kinase 66 2e-10
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 66 2e-10
YKL161c [T] KOG0660 Mitogen-activated protein kinase 66 2e-10
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 66 2e-10
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 66 2e-10
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 66 2e-10
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 66 2e-10
CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 66 2e-10
At5g55090 [T] KOG0198 MEKK and related serine/threonine protein ... 66 2e-10
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 66 2e-10
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 66 2e-10
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 66 2e-10
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 65 3e-10
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 65 3e-10
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 65 3e-10
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 65 3e-10
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 65 3e-10
At3g25840 [A] KOG0670 U4/U6-associated splicing factor PRP4 65 3e-10
7299437 [R] KOG0586 Serine/threonine protein kinase 65 3e-10
Hs4502885_2 [T] KOG0671 LAMMER dual specificity kinases 65 3e-10
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 65 4e-10
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 65 4e-10
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 65 4e-10
Hs4758008 [T] KOG0671 LAMMER dual specificity kinases 65 4e-10
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 65 4e-10
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 65 4e-10
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 65 4e-10
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 65 4e-10
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 65 4e-10
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 65 4e-10
CE04724 [T] KOG0983 Mitogen-activated protein kinase (MAPK) kina... 65 4e-10
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 65 4e-10
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 4e-10
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 65 4e-10
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 65 4e-10
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 65 5e-10
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 65 5e-10
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 65 5e-10
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 65 5e-10
Hs22045050 [T] KOG0671 LAMMER dual specificity kinases 65 5e-10
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 65 5e-10
Hs13376582 [T] KOG0198 MEKK and related serine/threonine protein... 65 5e-10
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 65 5e-10
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 65 5e-10
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 5e-10
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 65 5e-10
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 65 5e-10
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 64 7e-10
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 64 7e-10
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 64 7e-10
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 64 7e-10
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 64 7e-10
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 64 7e-10
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 64 7e-10
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 64 7e-10
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 64 7e-10
CE27177 [T] KOG4279 Serine/threonine protein kinase 64 7e-10
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 64 7e-10
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 64 7e-10
At1g78290 [T] KOG0583 Serine/threonine protein kinase 64 7e-10
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 64 7e-10
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 64 7e-10
At1g07150 [T] KOG0198 MEKK and related serine/threonine protein ... 64 7e-10
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 64 9e-10
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 64 9e-10
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 64 9e-10
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 64 9e-10
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 64 9e-10
SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases 64 9e-10
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 64 9e-10
Hs4505811 [T] KOG0583 Serine/threonine protein kinase 64 9e-10
Hs22066219 [T] KOG1151 Tousled-like protein kinase 64 9e-10
>YDL028c [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 764
Score = 525 bits (1352), Expect = e-148
Identities = 316/787 (40%), Positives = 441/787 (55%), Gaps = 157/787 (19%)
Query: 57 TSNHTEDQSQSTVF-TMVNKQFQPSMTTMNTVVKEXXXXXXXXXXXXXKYNKLNEESLMK 115
TS HT S ST+F + Q SMTTMNT ++ +
Sbjct: 85 TSGHTSTSSHSTLFGRYLRNNHQTSMTTMNT----------------------SDIEINV 122
Query: 116 DDTHSHTSQKFKVLQQSMKEELYNSTTKSSNKRNRRF-ITSRLSSLGPAKR--NLSTSFN 172
++ + ++ + L+Q+MKE++ T K + +R++RF I++R + LGPAKR L+ F+
Sbjct: 123 GNSLDKSFERIRNLRQNMKEDI---TAKYAERRSKRFLISNRTTKLGPAKRAMTLTNIFD 179
Query: 173 VDSPSESRVXXXXXXXXXXXXXXXXXXXDIENSHTSNSSNTGYRYHDHNIFLETHRQHST 232
D P NS N +
Sbjct: 180 EDVP--------------------------------NSPNQP---------INARETVEL 198
Query: 233 PSHDENKDPSANLQPNINYENIDFGDLNPYQYLKKYNLPSGELPYISKVYFERQKEENRK 292
P D ++ + N +Y++IDFGDLNP QY+KK+NLP+ +LP IS++YF++Q+EENR+
Sbjct: 199 PLEDSHQTNFKERRENTDYDSIDFGDLNPIQYIKKHNLPTSDLPLISQIYFDKQREENRQ 258
Query: 293 TVLRKATSGTLALKREFTQYR--------------RTQTARQPRRKHNFGTDK------- 331
LRK +S L K + + QPRRK + G+
Sbjct: 259 AALRKHSSRELLYKSRSSSSSLSSNNLLANKDNSITSNNGSQPRRKVSTGSSSSKSSIEI 318
Query: 332 ---------TSLQDPLSSPLQKNQLVFQEVDREL---ANKREALKPLDVNNPSS----SQ 375
TS +SP+ K +++ + R + KRE L+ + +N + Q
Sbjct: 319 RRALKENIDTSNNSNFNSPIHK---IYKGISRNKDSDSEKREVLRNISINANHADNLLQQ 375
Query: 376 EAKRPK------YENDHVPEDYRPPFFSHRKAPSPHDSKPFKKVEIVEPPKSTVEVIPLK 429
E KR K N+++ F+ HR AP P + KKVEIVEP KS
Sbjct: 376 ENKRLKRSLDDAITNENINSKNLEVFY-HRPAPKPPVT---KKVEIVEPAKS-------- 423
Query: 430 SEGCDVSSKLNKGDNYLNYNGSFDTKKRTSYAVPTITVNGTAYEKVELLXXXXXXXXXXX 489
+S+ N ITVN + YEK+ELL
Sbjct: 424 ---ASLSNNRN-----------------------IITVNDSQYEKIELLGRGGSSRVYKV 457
Query: 490 XXXDHKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME 549
++VYALKRVSFD FD+SSIDGFKGEIELL+KL++++RV++L+DY MG G+L+L+ME
Sbjct: 458 KGSGNRVYALKRVSFDAFDDSSIDGFKGEIELLEKLKDQKRVIQLLDYEMGDGLLYLIME 517
Query: 550 CGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGMLK 609
CG+HDLSQ+L QRS +P D FVR++ +EM+ C+KVVHDA IVHSDLKPANFV VKG+LK
Sbjct: 518 CGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVKGILK 577
Query: 610 IIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQ---AKWKVGKPSDV 666
IIDFGIANAVP+HTVNIYR+ QIGTPNYMAPE LVAMN+T+N Q KWKVG+PSD+
Sbjct: 578 IIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDM 637
Query: 667 WSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCL 726
WSCGCI+YQM+YGKPPYG+FQG NRL AIMNPDVKIP+PE S IP++ I+ +++CL
Sbjct: 638 WSCGCIIYQMIYGKPPYGSFQGQNRLLAIMNPDVKIPFPEHTSNNEKIPKSAIELMKACL 697
Query: 727 ERNPISRVTIDQLLSGALINPVTVTKFFIHDLIKNAVNYGCDQKHVNNERVEELSEDVWN 786
RNP R T+D++LS + P ++ + DLI+NAV YG ++ H++ + + ++ + V
Sbjct: 698 YRNPDKRWTVDKVLSSTFLQPFMISGSIMEDLIRNAVRYGSEKPHISQDDLNDVVDTVLR 757
Query: 787 KLAEFKL 793
K A++K+
Sbjct: 758 KFADYKI 764
>Hs4507719 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 841
Score = 191 bits (486), Expect = 3e-48
Identities = 101/286 (35%), Positives = 172/286 (59%), Gaps = 11/286 (3%)
Query: 458 TSYAVPTITVNGTAYEKVELLXXXXXXXXXXXXXXDHKVYALKRVSFDEFDESSIDGFKG 517
+S A I+V G Y ++ + ++YA+K V+ +E D ++D ++
Sbjct: 495 SSSANECISVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRN 554
Query: 518 EIELLKKLE-NKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHF 576
EI L KL+ + ++++L DY + ++++MECG DL+ L ++ I D + ++
Sbjct: 555 EIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSI--DPWERKSYW 612
Query: 577 QEMIKCVKVVHDADIVHSDLKPANFVFVKGMLKIIDFGIANAVPDHTVNIYRDNQIGTPN 636
+ M++ V +H IVHSDLKPANF+ V GMLK+IDFGIAN + T ++ +D+Q+GT N
Sbjct: 613 KNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSVVKDSQVGTVN 672
Query: 637 YMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGN-NRLYAI 695
YM PE + M+ +R +G ++K K+ SDVWS GCILY M YGK P+ ++L+AI
Sbjct: 673 YMPPEAIKDMSSSRENG-KSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAI 731
Query: 696 MNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLS 741
++P+ +I +P+ + + + D ++ CL+R+P R++I +LL+
Sbjct: 732 IDPNHEIEFPD------IPEKDLQDVLKCCLKRDPKQRISIPELLA 771
>Hs20547712 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 841
Score = 191 bits (486), Expect = 3e-48
Identities = 101/286 (35%), Positives = 172/286 (59%), Gaps = 11/286 (3%)
Query: 458 TSYAVPTITVNGTAYEKVELLXXXXXXXXXXXXXXDHKVYALKRVSFDEFDESSIDGFKG 517
+S A I+V G Y ++ + ++YA+K V+ +E D ++D ++
Sbjct: 495 SSSANECISVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRN 554
Query: 518 EIELLKKLE-NKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHF 576
EI L KL+ + ++++L DY + ++++MECG DL+ L ++ I D + ++
Sbjct: 555 EIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSI--DPWERKSYW 612
Query: 577 QEMIKCVKVVHDADIVHSDLKPANFVFVKGMLKIIDFGIANAVPDHTVNIYRDNQIGTPN 636
+ M++ V +H IVHSDLKPANF+ V GMLK+IDFGIAN + T ++ +D+Q+GT N
Sbjct: 613 KNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSVVKDSQVGTVN 672
Query: 637 YMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGN-NRLYAI 695
YM PE + M+ +R +G ++K K+ SDVWS GCILY M YGK P+ ++L+AI
Sbjct: 673 YMPPEAIKDMSSSRENG-KSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAI 731
Query: 696 MNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLS 741
++P+ +I +P+ + + + D ++ CL+R+P R++I +LL+
Sbjct: 732 IDPNHEIEFPD------IPEKDLQDVLKCCLKRDPKQRISIPELLA 771
>At1g77720 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 720
Score = 177 bits (450), Expect = 4e-44
Identities = 111/345 (32%), Positives = 177/345 (51%), Gaps = 41/345 (11%)
Query: 435 VSSKLNKGDNY---LNYNGSFDTKKRTSYAVPTITVNGTAYEKVELLXXXXXXXXXXXXX 491
VSS+ K D + + G +KR VNG Y+++ +
Sbjct: 303 VSSQPQKSDKHEKVASSKGPSAPRKRNYDPDLFFKVNGKLYQRLGKIGSGGSSEVHKVIS 362
Query: 492 XDHKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQ---------- 541
D +YALK++ D ++ GF EI LKKL+ K +++LIDY +
Sbjct: 363 SDCTIYALKKIKLKGRDYATAYGFCQEIGYLKKLKGKTNIIQLIDYEVTDKTLLQEVLNG 422
Query: 542 ------------GVLFLLMECGEHDLSQVLTQR------SKIPFDTEFVRYHFQEMIKCV 583
G +++++E GE DL+ +L+Q+ S D ++R+++Q++++ V
Sbjct: 423 TMSNKDGRVKEDGFIYMVLEYGEIDLAHMLSQKWREIEGSDRTIDENWLRFYWQQILQAV 482
Query: 584 KVVHDADIVHSDLKPANFVFVKGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETL 643
+H+ IVHSDLKPANF+ V+G LK+IDFGIA A+ T NI RD+Q+GT +YM+PE
Sbjct: 483 NTIHEERIVHSDLKPANFLLVRGFLKLIDFGIAKAINSDTTNIQRDSQVGTLSYMSPEAF 542
Query: 644 VAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGN-NRLYAIMNPDVKI 702
+ +D K G+PSD+WS GCILYQMVYG+ P+ ++ + I +P+ +I
Sbjct: 543 MC---NESDENGNTIKCGRPSDIWSLGCILYQMVYGRTPFADYKTFWAKFKVITDPNHEI 599
Query: 703 PYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALINP 747
Y + + +ID ++ CL + R I +LL + P
Sbjct: 600 TYNQLSN------PWLIDLMKKCLAWDRNQRWRIPELLQHPFLAP 638
>ECU02g0510 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 586
Score = 159 bits (401), Expect = 2e-38
Identities = 90/246 (36%), Positives = 137/246 (55%), Gaps = 21/246 (8%)
Query: 496 VYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDL 555
VYALKRV DE + + EI LL K + +V++ID+ +G+ L +L+E GE DL
Sbjct: 312 VYALKRVELIG-DEKMLSSYINEINLLYKFKGTSEIVEIIDHEVGEDYLHILLEYGETDL 370
Query: 556 SQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGMLKIIDFGI 615
S+++ + F++ +++M+ VK VH I+H DLKPANF+FVKG +K+IDFGI
Sbjct: 371 SKIIRKGG---LSMNFIKDVWEQMLLIVKRVHIERIIHCDLKPANFLFVKGRVKLIDFGI 427
Query: 616 ANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQ 675
+ + + T +I + Q GT NYM+PE + Q K KV + SD+WS GCILY+
Sbjct: 428 SKVIRNDTTSILSEEQCGTVNYMSPEAVT----------QNKSKVARSSDIWSLGCILYE 477
Query: 676 MVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVT 735
MV+ PP + + + + Y K+ + + ++ CL R+P R T
Sbjct: 478 MVHSNPPLHEYPNLIQKIQRLQEYSEFKYTSKN-------KAAVMVMKECLARDPKKRPT 530
Query: 736 IDQLLS 741
ID LL+
Sbjct: 531 IDNLLN 536
>7300288 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 630
Score = 141 bits (356), Expect = 3e-33
Identities = 88/254 (34%), Positives = 136/254 (52%), Gaps = 19/254 (7%)
Query: 497 YALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHM--GQGVLFLLMECGEHD 554
+ALK V + D + G+ E +LL KL+ VV L DY + + L+++ME G+ D
Sbjct: 363 FALKVVDL-QADPQVVQGYLNETKLLAKLQGNVCVVALYDYQLVREESKLYMVMEKGDCD 421
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQ----EMIKCVKVVHDADIVHSDLKPANFVFVKGMLKI 610
L+++L + T Y +M++ V +H ++HSDLKPANF+ V G LK+
Sbjct: 422 LNKILQS-----YTTNLPLYSLMNILYQMLQAVNYIHQHGVIHSDLKPANFLMVSGRLKL 476
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLV---AMNFTRNDGEQAKWKVGKPSDVW 667
IDFGIA+ + + +I + +Q GT NY++PE L N +Q K K+ SDVW
Sbjct: 477 IDFGIASNIAVDSTSIIKFSQAGTFNYISPEALTDTSTGNSPMRRADQPKIKISTKSDVW 536
Query: 668 SCGCILYQMVYGKPPYGTFQG-NNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCL 726
S GCILY ++Y K P+G + ++ AI P I YP + P ++ ++CL
Sbjct: 537 SLGCILYLLLYQKTPFGHIRNVYAKMSAITTPGTSIEYP---AIPPYYPIMLVHMAKNCL 593
Query: 727 ERNPISRVTIDQLL 740
+ NP R + +LL
Sbjct: 594 QLNPKKRPSCTELL 607
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 97.4 bits (241), Expect = 7e-20
Identities = 73/236 (30%), Positives = 113/236 (46%), Gaps = 30/236 (12%)
Query: 513 DGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFV 572
D EI +L +++ + G + +L C DL+ + + K+P E V
Sbjct: 52 DNLLKEISILSTIDHPNIIRFYEAIETGDRIFLVLEYCSGGDLAGYINRHGKVP---EAV 108
Query: 573 RYHFQEMIKC-VKVVHDADIVHSDLKPANFVF----VKGMLKIIDFGIANAVPDHTVNIY 627
HF + ++V+ + +H DLKP N + V +LKI DFG A ++ ++
Sbjct: 109 AKHFMRQLALGLQVLQEKHFIHRDLKPQNLLLSSKEVTPLLKIGDFGFARSLTPESM--- 165
Query: 628 RDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQ 687
+ G+P YMAPE + RN AK +D+WS G IL+Q+V GKPP F
Sbjct: 166 AETFCGSPLYMAPEII------RNQKYDAK------ADLWSAGAILFQLVTGKPP---FD 210
Query: 688 GNNRLYAIMN--PDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLS 741
GNN + N D ++ +PE D+ + P +D RS L RNPI R+T + +
Sbjct: 211 GNNHIQLFHNIVRDTELKFPE-DTRNEIHP-DCVDLCRSLLRRNPIERLTFREFFN 264
>At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 422
Score = 95.5 bits (236), Expect = 3e-19
Identities = 111/414 (26%), Positives = 175/414 (41%), Gaps = 66/414 (15%)
Query: 356 LANKREALKPLDVNNPSSSQEAKRPKY-------ENDHVPEDYRPPFFSHRKAP---SPH 405
L RE L P DV + RP + H+P F +H P +P
Sbjct: 35 LVKSREYLIPDDVVAVGGDIKGLRPPVLQLQPAMKLSHIPRGSTWDFVTHFAPPETVAPP 94
Query: 406 DSKPFKKVEIVEPPKSTVEVIPL-KSEGCDVSSKLNKGDNYLNYNGSFDTKKRTSYAVPT 464
S + E VE ++ IPL E C S +NKGD+ + S P
Sbjct: 95 SSSSEAREEEVETEETGAMFIPLGDKETC--SFTVNKGDS----------SRTISNTSPI 142
Query: 465 ITVNG---TAYEKVELLXXXXXXXXXXXXXXDHKVYALKRVSFDEFDESS-----IDGFK 516
G T ++K +LL D +A K VS D+ S I +
Sbjct: 143 YASEGSFITCWQKGQLLGRGSLGSVYEGISADGDFFAFKEVSL--LDQGSQAHEWIQQVE 200
Query: 517 GEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHF 576
G I LL +L++ Q +V+ + L++ +E + L QR+++ V +
Sbjct: 201 GGIALLSQLQH-QNIVRYRGTTKDESNLYIFLELVTQGSLRKLYQRNQL--GDSVVSLYT 257
Query: 577 QEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLKIIDFGIANAVPDHTVNIYRDNQIGTP 635
++++ +K +HD +H ++K AN V G +K+ DFG+A + +++R TP
Sbjct: 258 RQILDGLKYLHDKGFIHRNIKCANVLVDANGTVKLADFGLAKVM-----SLWR-----TP 307
Query: 636 --NYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLY 693
N+MAPE V +N DG G P+D+WS GC + +M+ G+ PY + LY
Sbjct: 308 YWNWMAPE--VILNPKDYDG------YGTPADIWSLGCTVLEMLTGQIPYSDLEIGTALY 359
Query: 694 AIMNPDV-KIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALIN 746
I + KIP ++ D I +CL+ NP R T +LL+ +N
Sbjct: 360 NIGTGKLPKIP--------DILSLDARDFILTCLKVNPEERPTAAELLNHPFVN 405
>Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1558
Score = 95.1 bits (235), Expect = 4e-19
Identities = 68/259 (26%), Positives = 130/259 (49%), Gaps = 24/259 (9%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEH 553
++ A+K + F D +I E+++ + +++ +V+ + + +++ ME C E
Sbjct: 1317 ELMAMKEIRFQPNDHKTIKETADELKIFEGIKHPN-LVRYFGVELHREEMYIFMEYCDEG 1375
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLKIID 612
L +V S++ +R + +++ + V+H+ IVH D+K AN F+ G++K+ D
Sbjct: 1376 TLEEV----SRLGLQEHVIRLYSKQITIAINVLHEHGIVHRDIKGANIFLTSSGLIKLGD 1431
Query: 613 FGIANAVPDHTVNIYRD--NQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
FG + + ++ + + + +GT YMAPE + TR GE G+ +D+WS G
Sbjct: 1432 FGCSVKLKNNAQTMPGEVNSTLGTAAYMAPEVI-----TRAKGEGH----GRAADIWSLG 1482
Query: 671 CILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNP 730
C++ +MV GK P+ ++ N ++ + K P PE+ + D + CLE +P
Sbjct: 1483 CVVIEMVTGKRPWHEYEHNFQIMYKVGMGHKPPIPER------LSPEGKDFLSHCLESDP 1536
Query: 731 ISRVTIDQLLSGALINPVT 749
R T QLL + + T
Sbjct: 1537 KMRWTASQLLDHSFVKVCT 1555
>Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1607
Score = 95.1 bits (235), Expect = 4e-19
Identities = 68/259 (26%), Positives = 130/259 (49%), Gaps = 24/259 (9%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEH 553
++ A+K + F D +I E+++ + +++ +V+ + + +++ ME C E
Sbjct: 1366 ELMAMKEIRFQPNDHKTIKETADELKIFEGIKHPN-LVRYFGVELHREEMYIFMEYCDEG 1424
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLKIID 612
L +V S++ +R + +++ + V+H+ IVH D+K AN F+ G++K+ D
Sbjct: 1425 TLEEV----SRLGLQEHVIRLYSKQITIAINVLHEHGIVHRDIKGANIFLTSSGLIKLGD 1480
Query: 613 FGIANAVPDHTVNIYRD--NQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
FG + + ++ + + + +GT YMAPE + TR GE G+ +D+WS G
Sbjct: 1481 FGCSVKLKNNAQTMPGEVNSTLGTAAYMAPEVI-----TRAKGEGH----GRAADIWSLG 1531
Query: 671 CILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNP 730
C++ +MV GK P+ ++ N ++ + K P PE+ + D + CLE +P
Sbjct: 1532 CVVIEMVTGKRPWHEYEHNFQIMYKVGMGHKPPIPER------LSPEGKDFLSHCLESDP 1585
Query: 731 ISRVTIDQLLSGALINPVT 749
R T QLL + + T
Sbjct: 1586 KMRWTASQLLDHSFVKVCT 1604
>YHR102w [T] KOG0201 Serine/threonine protein kinase
Length = 1080
Score = 94.0 bits (232), Expect = 8e-19
Identities = 69/253 (27%), Positives = 125/253 (49%), Gaps = 25/253 (9%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEH 553
+VYA+K ++ D D ++ + EI+ L L+ + + ++ L+++ME C
Sbjct: 47 RVYAIKVLNLDS-DSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGG 105
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFV-KGMLKIID 612
L +L + KI D +++ +E++ +K +H +++H D+K AN + +G +K+ D
Sbjct: 106 SLRSLL-RPGKI--DEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCD 162
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG+A V + ++ R GTP +MAPE ++ +G KV D+WS G
Sbjct: 163 FGVAAQV--NQTSLRRQTMAGTPYWMAPEVIM-------EGVYYDTKV----DIWSLGIT 209
Query: 673 LYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPIS 732
Y++ G PPY + + I+ K P E S+ T ++ + I CL+ +P
Sbjct: 210 TYEIATGNPPYCDVEALRAMQLIIKS--KPPRLEDRSYST----SLKEFIALCLDEDPKE 263
Query: 733 RVTIDQLLSGALI 745
R++ D LL I
Sbjct: 264 RLSADDLLKSKFI 276
>At3g13530 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1368
Score = 93.6 bits (231), Expect = 1e-18
Identities = 65/246 (26%), Positives = 120/246 (48%), Gaps = 24/246 (9%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DLS 556
A+K+VS + + ++ EI+LLK L +K +VK + + L +++E E+ L+
Sbjct: 47 AIKQVSLENIVQEDLNTIMQEIDLLKNLNHKN-IVKYLGSSKTKTHLHIILEYVENGSLA 105
Query: 557 QVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDFGI 615
++ PF V + ++++ + +H+ ++H D+K AN + K G++K+ DFG+
Sbjct: 106 NIIKPNKFGPFPESLVAVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGLVKLADFGV 165
Query: 616 ANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQ 675
A + + VN + + +GTP +MAPE + V SD+WS GC + +
Sbjct: 166 ATKLNEADVNTH--SVVGTPYWMAPEVIEMSG------------VCAASDIWSVGCTVIE 211
Query: 676 MVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVT 735
++ PPY Q L+ I+ D P P+ + + D +R C +++ R
Sbjct: 212 LLTCVPPYYDLQPMPALFRIVQDD-NPPIPDS------LSPDITDFLRQCFKKDSRQRPD 264
Query: 736 IDQLLS 741
LLS
Sbjct: 265 AKTLLS 270
>At3g07980 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1367
Score = 93.6 bits (231), Expect = 1e-18
Identities = 65/246 (26%), Positives = 119/246 (47%), Gaps = 24/246 (9%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DLS 556
A+K+VS + + ++ EI+LLK L +K +VK + + L +++E E+ L+
Sbjct: 47 AIKQVSLENIGQEDLNTIMQEIDLLKNLNHKN-IVKYLGSLKTKTHLHIILEYVENGSLA 105
Query: 557 QVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDFGI 615
++ PF V + ++++ + +H+ ++H D+K AN + K G++K+ DFG+
Sbjct: 106 NIIKPNKFGPFPESLVTVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGLVKLADFGV 165
Query: 616 ANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQ 675
A + + N + + +GTP +MAPE + V SD+WS GC + +
Sbjct: 166 ATKLNEADFNTH--SVVGTPYWMAPEVIELSG------------VCAASDIWSVGCTIIE 211
Query: 676 MVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVT 735
++ PPY Q LY I+ D P P+ + + D +R C +++ R
Sbjct: 212 LLTCVPPYYDLQPMPALYRIVQDDTP-PIPDS------LSPDITDFLRLCFKKDSRQRPD 264
Query: 736 IDQLLS 741
LLS
Sbjct: 265 AKTLLS 270
>SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1062
Score = 93.2 bits (230), Expect = 1e-18
Identities = 79/287 (27%), Positives = 129/287 (44%), Gaps = 43/287 (14%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQ 557
A+K+V + +S + K EI+LLK L++ V Y + +L C L
Sbjct: 36 AVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRGSYQTNDSLCIILEYCENGSLRS 95
Query: 558 VLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDFGIA 616
+ KIP + Y FQ +++ + +H+ ++H D+K AN + K G +K+ DFG+A
Sbjct: 96 ICKNFGKIP-ENLVALYTFQ-VLQGLLYLHNQGVIHRDIKGANILTTKDGTIKLADFGVA 153
Query: 617 ---NAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCIL 673
NA+ DH+V +G+P +MAPE + + T SD+WS GC +
Sbjct: 154 TKINALEDHSV-------VGSPYWMAPEVIELVGATT------------ASDIWSVGCTV 194
Query: 674 YQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISR 733
+++ G PPY + L+ ++ D P P I + C +++P R
Sbjct: 195 IELLDGNPPYYDLDPTSALFRMVK-DEHPPLPSN------ISSAAKSFLMQCFQKDPNLR 247
Query: 734 VTIDQLLSGA-LINPVTVTKFFIHDLIKNAVNYGCDQKHVNNERVEE 779
+ +LL +I T +KF D I Y NERV+E
Sbjct: 248 IKTRKLLKHPWVIMNQTSSKF--SDAIDEVQKY--------NERVKE 284
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 92.4 bits (228), Expect = 2e-18
Identities = 67/239 (28%), Positives = 119/239 (49%), Gaps = 26/239 (10%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQ 557
A+K + + I + EIE+L+KL++ + +++++D ++ E + +L +
Sbjct: 33 AMKFIMKQGKTDKDIHSLRQEIEILRKLKH-ENIIEMLDSFENAREFCVVTEFAQGELFE 91
Query: 558 VLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKG-MLKIIDFGIA 616
+L +P E V+ ++++K + +H I+H D+KP N + G ++K+ DFG A
Sbjct: 92 ILEDDKCLP--EEQVQAIAKQLVKALDYLHSNRIIHRDMKPQNILIGAGSVVKLCDFGFA 149
Query: 617 NAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQM 676
A+ +TV + R + GTP YMAPE + + R D+WS G ILY++
Sbjct: 150 RAMSTNTV-VLRSIK-GTPLYMAPELVKEQPYDRT------------VDLWSLGVILYEL 195
Query: 677 VYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVT 735
G+PP+ T N +YA++ VK P D T ++ L + P SR+T
Sbjct: 196 YVGQPPFYT----NSVYALIRHIVKDPVKYPDEMSTYFE----SFLKGLLNKEPHSRLT 246
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 91.7 bits (226), Expect = 4e-18
Identities = 69/231 (29%), Positives = 113/231 (48%), Gaps = 35/231 (15%)
Query: 522 LKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DLSQVLTQRSKIPFDTEFVRYHFQEMI 580
L+KL + + KL + L+ L+E H D ++ + + + RY+ ++I
Sbjct: 177 LQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSL--NETCARYYASQII 234
Query: 581 KCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVN---------IYRDN 630
V +H+ I+H D+KP N + K M +K+ DFG A +P+ N +Y +
Sbjct: 235 DAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKS 294
Query: 631 Q--IGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQG 688
+ +GT Y++PE L+ N+T + D+W+ GCILYQM+ GKPP F+
Sbjct: 295 KSFVGTAEYVSPE-LLNDNYTDSR-----------CDIWAFGCILYQMLAGKPP---FKA 339
Query: 689 NNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQL 739
N Y +KI Y +F P+ V D ++ L R+P R+TI Q+
Sbjct: 340 ANE-YLTFQKVMKIQY----AFTAGFPQIVKDLVKKLLVRDPNDRLTIKQI 385
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 90.9 bits (224), Expect = 7e-18
Identities = 71/251 (28%), Positives = 121/251 (47%), Gaps = 28/251 (11%)
Query: 493 DHKVYALKRVSFDEFDES-SIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-C 550
++KVYA K + + + EIEL + L +K VV+ Y + +++L+E C
Sbjct: 104 NNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKH-VVQFYHYFEDKENIYILLEYC 162
Query: 551 GEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LK 609
++ +L R K+ + E VRY+ ++++ +K +H+ +I+H DLK NF + M LK
Sbjct: 163 SRRSMAHILKAR-KVLTEPE-VRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELK 220
Query: 610 IIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
+ DFG+A + + R GTPNY++PE L K G SD+W+
Sbjct: 221 VGDFGLAARL--EPLEHRRRTICGTPNYLSPEVL------------NKQGHGCESDIWAL 266
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
GC++Y M+ G+PP+ T I +P + + I S L +N
Sbjct: 267 GCVMYTMLLGRPPFETTNLKETYRCIREARYTMP--------SSLLAPAKHLIASMLSKN 318
Query: 730 PISRVTIDQLL 740
P R ++D ++
Sbjct: 319 PEDRPSLDDII 329
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 90.1 bits (222), Expect = 1e-17
Identities = 67/253 (26%), Positives = 123/253 (48%), Gaps = 26/253 (10%)
Query: 516 KGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTEFVRY 574
K E+++ +L++ +++L +Y ++L++E C ++++ L R K PF R+
Sbjct: 58 KNEVKIHCQLKHPS-ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVK-PFSENEARH 115
Query: 575 HFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVNIYRDNQIG 633
++I + +H I+H DL +N + + M +KI DFG+A + Y G
Sbjct: 116 FMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHY--TLCG 173
Query: 634 TPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLY 693
TPNY++PE TR+ G SDVWS GC+ Y ++ G+PP+ T N L
Sbjct: 174 TPNYISPEIA-----TRSAH-------GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLN 221
Query: 694 AIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALINPVTVTKF 753
++ D ++P T + D I L RNP R+++ +L ++ + TK
Sbjct: 222 KVVLADYEMP--------TFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKS 273
Query: 754 FIHDLIKNAVNYG 766
++++++ G
Sbjct: 274 KDLGTVEDSIDSG 286
>CE18454 [T] KOG4717 Serine/threonine protein kinase
Length = 1016
Score = 89.7 bits (221), Expect = 2e-17
Identities = 66/250 (26%), Positives = 121/250 (48%), Gaps = 28/250 (11%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHD 554
++ A+K + + DE+S E+ +K +++ +V+L + Q +FL++E G++D
Sbjct: 51 EMVAVKIIDKTKMDEASTSQIMKEVRCMKLVQHAN-IVRLYEVLDTQTKIFLILELGDYD 109
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK--GMLKIID 612
L + + K ++ + +F +++ + H +VH DLKP N VF + GM+K+ D
Sbjct: 110 LHDFIIKHEKGVCES-LAQQYFCQIMTAIDYCHQLHVVHRDLKPENVVFFEKLGMVKLTD 168
Query: 613 FGIANAV-PDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGC 671
FG +N+ P +N G+ Y APE L+ ++ DVWS G
Sbjct: 169 FGFSNSYEPGEQLN----TSCGSLAYSAPEILLGDSYD-----------APAVDVWSLGV 213
Query: 672 ILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPI 731
ILY +V G+ P+ + L I++ IP V+ + I+S L R P
Sbjct: 214 ILYMLVCGRLPFQEANDSETLTKILDCKYSIP--------DVLSDECRNLIQSMLVREPQ 265
Query: 732 SRVTIDQLLS 741
R ++++++S
Sbjct: 266 KRASLEKIVS 275
>At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 582
Score = 89.4 bits (220), Expect = 2e-17
Identities = 74/263 (28%), Positives = 125/263 (47%), Gaps = 54/263 (20%)
Query: 497 YALKRVSFDEF-DESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHD 554
+A KR+S ++ E ++ + E+E+++ L +V + + ++L+ME C +
Sbjct: 92 FACKRISKEKLRTEIDVEDVRREVEIMRCLPKHPNIVSFKEAFEDKDAVYLVMEICEGGE 151
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQE---------MIKCVKVVHDADIVHSDLKPANFVFVK 605
L FD R H+ E +++ VKV H+ ++H DLKP NF+F
Sbjct: 152 L-----------FDRIVSRGHYTERAAASVAKTILEVVKVCHEHGVIHRDLKPENFLFSN 200
Query: 606 G----MLKIIDFGIANAVPDHTVNIYRDNQI-GTPNYMAPETLVAMNFTRNDGEQAKWKV 660
G LK IDFG++ R N+I G+P YMAPE L RN G +
Sbjct: 201 GTETAQLKAIDFGLSIFFKP----AQRFNEIVGSPYYMAPEVL-----RRNYGPEI---- 247
Query: 661 GKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDV---KIPYPEKDSFGTVIPRT 717
DVWS G ILY ++ G PP+ +AI+ ++ + P+P+ +
Sbjct: 248 ----DVWSAGVILYILLCGVPPFWAETEEGIAHAIVRGNIDFERDPWPK-------VSHE 296
Query: 718 VIDTIRSCLERNPISRVTIDQLL 740
+ +++ L+ NP SR+T+ ++L
Sbjct: 297 AKELVKNMLDANPYSRLTVQEVL 319
>Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 89.0 bits (219), Expect = 3e-17
Identities = 79/297 (26%), Positives = 130/297 (43%), Gaps = 40/297 (13%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEH 553
+V A+K+V ES + EI ++++ ++ VVK + L+++ME CG
Sbjct: 51 QVVAIKQVPV----ESDLQEIIKEISIMQQCDSPY-VVKYYGSYFKNTDLWIVMEYCGAG 105
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIID 612
+S ++ R+K + E + +K ++ +H +H D+K N + +G K+ D
Sbjct: 106 SVSDIIRLRNKTLIEDEIATI-LKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLAD 164
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG+A + D R+ IGTP +MAPE + + + +D+WS G
Sbjct: 165 FGVAGQLTDTMAK--RNTVIGTPFWMAPEVIQEIGYNC------------VADIWSLGIT 210
Query: 673 LYQMVYGKPPYGTFQGNNRLYAI-MNPDVKIPYPE--KDSFGTVIPRTVIDTIRSCLERN 729
+M GKPPY ++ I NP PE D F D ++ CL +N
Sbjct: 211 SIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDF--------TDFVKKCLVKN 262
Query: 730 PISRVTIDQLLSGALI---NPVTVTKFFIHDLIKNAVNYGCDQKHVNNERVEELSED 783
P R T QLL I PV++ + DLI A+ + +EE E+
Sbjct: 263 PEQRATATQLLQHPFIKNAKPVSI----LRDLITEAMEIKAKRHEEQQRELEEEEEN 315
>Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 88.6 bits (218), Expect = 3e-17
Identities = 79/297 (26%), Positives = 130/297 (43%), Gaps = 40/297 (13%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEH 553
+V A+K+V ES + EI ++++ ++ VVK + L+++ME CG
Sbjct: 51 QVVAIKQVPV----ESDLQEIIKEISIMQQCDSPY-VVKYYGSYFKNTDLWIVMEYCGAG 105
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIID 612
+S ++ R+K + E + +K ++ +H +H D+K N + +G K+ D
Sbjct: 106 SVSDIIRLRNKTLIEDEIATI-LKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLAD 164
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG+A + D R+ IGTP +MAPE + + + +D+WS G
Sbjct: 165 FGVAGQLTDTMAK--RNTVIGTPFWMAPEVIQEIGYNC------------VADIWSLGIT 210
Query: 673 LYQMVYGKPPYGTFQGNNRLYAI-MNPDVKIPYPE--KDSFGTVIPRTVIDTIRSCLERN 729
+M GKPPY ++ I NP PE D F D ++ CL +N
Sbjct: 211 SIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDF--------TDFVKKCLVKN 262
Query: 730 PISRVTIDQLLSGALI---NPVTVTKFFIHDLIKNAVNYGCDQKHVNNERVEELSED 783
P R T QLL I PV++ + DLI A+ + +EE E+
Sbjct: 263 PEQRATATQLLQHPFIKNAKPVSI----LRDLITEAMEIKAKRHDEQQRELEEEEEN 315
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 88.6 bits (218), Expect = 3e-17
Identities = 64/238 (26%), Positives = 114/238 (47%), Gaps = 25/238 (10%)
Query: 531 VVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDA 589
+++L +Y ++L++E C ++++ L R K PF R+ ++I + +H
Sbjct: 72 ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVK-PFSENEARHFMHQIITGMLYLHSH 130
Query: 590 DIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNF 648
I+H DL +N + + M +KI DFG+A + Y GTPNY++PE
Sbjct: 131 GILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHY--TLCGTPNYISPEIA----- 183
Query: 649 TRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKD 708
TR+ G SDVWS GC+ Y ++ G+PP+ T N L ++ D ++P
Sbjct: 184 TRSAH-------GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMP----- 231
Query: 709 SFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALINPVTVTKFFIHDLIKNAVNYG 766
T + D I L RNP R+++ +L ++ + TK ++++++ G
Sbjct: 232 ---TFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSG 286
>7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1612
Score = 88.6 bits (218), Expect = 3e-17
Identities = 70/250 (28%), Positives = 117/250 (46%), Gaps = 22/250 (8%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEH 553
++ A+K ++ + ++ E+++L+ +++K +V+ + + L + ME C E
Sbjct: 1347 ELMAMKEIAIQPGETRALKNVAEELKILEGIKHKN-LVRYYGIEVHREELLIFMELCSEG 1405
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM--LKII 611
L ++ +P R +++ V +H IVH D+K AN V G LK+
Sbjct: 1406 TLESLVELTGNLP--EALTRRFTAQLLSGVSELHKHGIVHRDIKTANIFLVDGSNSLKLG 1463
Query: 612 DFGIANAVPDHT-VNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG A + HT V +GT YMAPE N +DG G+ +D+WS G
Sbjct: 1464 DFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTN---SDGH------GRAADIWSVG 1514
Query: 671 CILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNP 730
C++ +M GK P+ F N + IM K+ EK + + D I CL+ +P
Sbjct: 1515 CVVVEMASGKRPWAQFDSN---FQIM---FKVGMGEKPQAPESLSQEGHDFIDHCLQHDP 1568
Query: 731 ISRVTIDQLL 740
R+T +LL
Sbjct: 1569 KRRLTAVELL 1578
>7303211 [T] KOG4717 Serine/threonine protein kinase
Length = 860
Score = 88.2 bits (217), Expect = 4e-17
Identities = 66/254 (25%), Positives = 117/254 (45%), Gaps = 27/254 (10%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQ 557
A+K V + D+ S E+ +K +++ VV+L + Q L+L++E G+
Sbjct: 47 AVKVVDKTKLDDVSKAHLFQEVRCMKLVQHPN-VVRLYEVIDTQTKLYLVLELGDGGDLY 105
Query: 558 VLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK--GMLKIIDFGI 615
+ E R +F+++++ + H +VH DLKP N VF + G++K+ DFG
Sbjct: 106 DYIMKHDSGLSEELARKYFRQILRAITYCHQLHVVHRDLKPENVVFFEKLGLVKLTDFGF 165
Query: 616 ANA-VPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILY 674
+N +P + + G+ Y APE L+ ++ D+WS G ILY
Sbjct: 166 SNKFLPGQKLETF----CGSLAYSAPEILLGDSYD-----------APAVDIWSLGVILY 210
Query: 675 QMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRV 734
+V G+ P+ + L IM+ +P + + D I S L R+P R
Sbjct: 211 MLVCGQAPFEKANDSETLTMIMDCKYTVP--------SHVSTDCRDLIASMLVRDPKKRA 262
Query: 735 TIDQLLSGALINPV 748
T++++ S A + P+
Sbjct: 263 TVEEIASSAWLKPI 276
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 88.2 bits (217), Expect = 4e-17
Identities = 66/241 (27%), Positives = 110/241 (45%), Gaps = 17/241 (7%)
Query: 512 IDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTE 570
++ + EI +L+++ ++ L D +FL+ E C + +L LT S + +
Sbjct: 71 LEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLT--SVVTLSEK 128
Query: 571 FVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVNIYRD 629
R +++ + V+ +H IVH DLKP N + + +KI DFG A + +
Sbjct: 129 KTRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDENHNVKITDFGFAKQLQEGEK---LT 185
Query: 630 NQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGN 689
N GTP Y+APETL F + G + D+W+CG I++ ++ G PP+ +
Sbjct: 186 NLCGTPGYLAPETLKCNMFEGSPG------YSQEVDIWACGVIMFTLLVGCPPFWHRKQM 239
Query: 690 NRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALINPVT 749
L IM PE I D IR CL +P R+T+ ++L N +
Sbjct: 240 VMLRNIMEGKYSFTSPE----WADISEDPKDLIRKCLVVDPSQRITVKEVLRHPFFNQMV 295
Query: 750 V 750
+
Sbjct: 296 L 296
>Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 588
Score = 87.8 bits (216), Expect = 6e-17
Identities = 67/228 (29%), Positives = 117/228 (50%), Gaps = 29/228 (12%)
Query: 518 EIELLKKLENKQRVVKLIDY--HMGQGVLFLLMEC-GEHDLSQVLTQRSKIPFDTEFVRY 574
EI +LKKL++ VVKL++ + L+++ E + + +V T + P + R+
Sbjct: 236 EIAILKKLDHPN-VVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLK---PLSEDQARF 291
Query: 575 HFQEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLKIIDFGIANAVPDHTVNIYRDNQIG 633
+FQ++IK ++ +H I+H D+KP+N V G +KI DFG++N + N +G
Sbjct: 292 YFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALL--SNTVG 349
Query: 634 TPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLY 693
TP +MAPE+L E K GK DVW+ G LY V+G+ P+ + R+
Sbjct: 350 TPAFMAPESL---------SETRKIFSGKALDVWAMGVTLYCFVFGQCPF----MDERIM 396
Query: 694 AIMN--PDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQL 739
+ + + +P++ I + D I L++NP SR+ + ++
Sbjct: 397 CLHSKIKSQALEFPDQPD----IAEDLKDLITRMLDKNPESRIVVPEI 440
>CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 525
Score = 87.4 bits (215), Expect = 8e-17
Identities = 75/278 (26%), Positives = 120/278 (42%), Gaps = 49/278 (17%)
Query: 496 VYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHD 554
V A+K+V D + + EI ++++ ++K VVK + L+++ME CG
Sbjct: 88 VLAIKKVPVD----TDLQEIIKEISIMQQCKSKY-VVKYYGSYFKHSDLWIVMEYCGAGS 142
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDF 613
+S ++ R K P + + ++ +K ++ +HD +H D+K N + G+ K+ DF
Sbjct: 143 ISDIMRARRK-PLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADF 201
Query: 614 GIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCIL 673
G+A + D R+ IGTP +MAPE + + + +D+WS G
Sbjct: 202 GVAGQLTDTMAK--RNTVIGTPFWMAPEVIEEIGYDTK------------ADIWSLGITA 247
Query: 674 YQMVYGKPPYGTFQGNNRLYAIMN---PDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNP 730
+M G+PPY ++ I P K P F D IRSCL + P
Sbjct: 248 IEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFN--------DFIRSCLIKKP 299
Query: 731 ISRVTIDQLLSGALINPVTVTKFFIHDLIKNAVNYGCD 768
R T +L H IKNA GCD
Sbjct: 300 EERKTALRLCE--------------HTFIKNAP--GCD 321
>CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 640
Score = 87.4 bits (215), Expect = 8e-17
Identities = 75/278 (26%), Positives = 120/278 (42%), Gaps = 49/278 (17%)
Query: 496 VYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHD 554
V A+K+V D + + EI ++++ ++K VVK + L+++ME CG
Sbjct: 60 VLAIKKVPVD----TDLQEIIKEISIMQQCKSKY-VVKYYGSYFKHSDLWIVMEYCGAGS 114
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDF 613
+S ++ R K P + + ++ +K ++ +HD +H D+K N + G+ K+ DF
Sbjct: 115 ISDIMRARRK-PLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADF 173
Query: 614 GIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCIL 673
G+A + D R+ IGTP +MAPE + + + +D+WS G
Sbjct: 174 GVAGQLTDTMAK--RNTVIGTPFWMAPEVIEEIGYDTK------------ADIWSLGITA 219
Query: 674 YQMVYGKPPYGTFQGNNRLYAIMN---PDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNP 730
+M G+PPY ++ I P K P F D IRSCL + P
Sbjct: 220 IEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFN--------DFIRSCLIKKP 271
Query: 731 ISRVTIDQLLSGALINPVTVTKFFIHDLIKNAVNYGCD 768
R T +L H IKNA GCD
Sbjct: 272 EERKTALRLCE--------------HTFIKNAP--GCD 293
>CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 421
Score = 87.4 bits (215), Expect = 8e-17
Identities = 75/278 (26%), Positives = 120/278 (42%), Gaps = 49/278 (17%)
Query: 496 VYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHD 554
V A+K+V D + + EI ++++ ++K VVK + L+++ME CG
Sbjct: 60 VLAIKKVPVD----TDLQEIIKEISIMQQCKSKY-VVKYYGSYFKHSDLWIVMEYCGAGS 114
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDF 613
+S ++ R K P + + ++ +K ++ +HD +H D+K N + G+ K+ DF
Sbjct: 115 ISDIMRARRK-PLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADF 173
Query: 614 GIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCIL 673
G+A + D R+ IGTP +MAPE + + + +D+WS G
Sbjct: 174 GVAGQLTDTMAK--RNTVIGTPFWMAPEVIEEIGYDTK------------ADIWSLGITA 219
Query: 674 YQMVYGKPPYGTFQGNNRLYAIMN---PDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNP 730
+M G+PPY ++ I P K P F D IRSCL + P
Sbjct: 220 IEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFN--------DFIRSCLIKKP 271
Query: 731 ISRVTIDQLLSGALINPVTVTKFFIHDLIKNAVNYGCD 768
R T +L H IKNA GCD
Sbjct: 272 EERKTALRLCE--------------HTFIKNAP--GCD 293
>CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 523
Score = 87.4 bits (215), Expect = 8e-17
Identities = 75/278 (26%), Positives = 120/278 (42%), Gaps = 49/278 (17%)
Query: 496 VYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHD 554
V A+K+V D + + EI ++++ ++K VVK + L+++ME CG
Sbjct: 88 VLAIKKVPVD----TDLQEIIKEISIMQQCKSKY-VVKYYGSYFKHSDLWIVMEYCGAGS 142
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDF 613
+S ++ R K P + + ++ +K ++ +HD +H D+K N + G+ K+ DF
Sbjct: 143 ISDIMRARRK-PLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADF 201
Query: 614 GIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCIL 673
G+A + D R+ IGTP +MAPE + + + +D+WS G
Sbjct: 202 GVAGQLTDTMAK--RNTVIGTPFWMAPEVIEEIGYDTK------------ADIWSLGITA 247
Query: 674 YQMVYGKPPYGTFQGNNRLYAIMN---PDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNP 730
+M G+PPY ++ I P K P F D IRSCL + P
Sbjct: 248 IEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFN--------DFIRSCLIKKP 299
Query: 731 ISRVTIDQLLSGALINPVTVTKFFIHDLIKNAVNYGCD 768
R T +L H IKNA GCD
Sbjct: 300 EERKTALRLCE--------------HTFIKNAP--GCD 321
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 87.4 bits (215), Expect = 8e-17
Identities = 72/266 (27%), Positives = 124/266 (46%), Gaps = 37/266 (13%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTEF-VRYH 575
EI + + L N +VK +Y +++++E C + + ++ +R I TEF RY+
Sbjct: 73 EITIHRSL-NHPNIVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSI---TEFECRYY 128
Query: 576 FQEMIKCVKVVHDADIVHSDLKPANFVFVKGML--KIIDFGIANAVPDHTVNIYRDNQIG 633
++I+ VK +HD I+H DLK N +F+ +L KI DFG+A + + G
Sbjct: 129 IYQIIQGVKYLHDNRIIHRDLKLGN-LFLNDLLHVKIGDFGLATRIEYEGER--KKTLCG 185
Query: 634 TPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLY 693
TPNY+APE L + D+WS GC++Y ++ G+PP+ T +
Sbjct: 186 TPNYIAPEILTKKGHSFE------------VDIWSIGCVMYTLLVGQPPFETKTLKDTYS 233
Query: 694 AIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALINPVTVTKF 753
I + ++P + + + D + + L+ NP SR I QLL+ + V F
Sbjct: 234 KIKKCEYRVP--------SYLRKPAADMVIAMLQPNPESRPAIGQLLNFEFLKGSKVPMF 285
Query: 754 FIHDLIKNAVNYGCDQKHVNNERVEE 779
+ A G +N+ +E+
Sbjct: 286 LPSSCLTMAPRIG------SNDTIED 305
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 87.0 bits (214), Expect = 1e-16
Identities = 112/489 (22%), Positives = 197/489 (39%), Gaps = 82/489 (16%)
Query: 281 VYFERQKEENRKTVL----RKATSGTLALKREFTQ----YRRTQTARQPRRKHNFG---- 328
+YF++ + + +L +K L K +F+ Y T ++ N G
Sbjct: 1 MYFDKDNSMSPRPLLPSDEQKLNINLLTKKEKFSHLDPHYDAKATPQRSTSNRNVGDLLL 60
Query: 329 ---TDKTSLQDPLSSPLQKNQLVFQEVDRELANKREALKPLDVNNPSSSQEAKRP--KYE 383
T K +Q L++ ++ + + L + + +K + +N+ + A +Y+
Sbjct: 61 EKRTAKPMIQKALTNTDNFIEMYHNQQRKNLDD--DTIKEVMINDENGKTVASTNDGRYD 118
Query: 384 NDHVPEDYRPPFFSHRKAPSPHDSKPFKKVEIVEPPKSTVEVIPLKSEGCDVSSKLNKGD 443
ND+ D A SPH K KV+I S P+ E SSK K
Sbjct: 119 NDYDNNDINDQKTLDNIAGSPHMEKNRNKVKIEHDSSSQK---PIAKE----SSKAQKN- 170
Query: 444 NYLNYNGSFDTKKRTSYAVPTITVNGTAYEKVELLXXXXXXXXXXXXXXDHKVYAL--KR 501
+ G D K + + AY V +L +K Y + K+
Sbjct: 171 --IIKKGIKDFKFGS-------VIGDGAYSTV-MLATSIDTKKRYAAKVLNKEYLIRQKK 220
Query: 502 VSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DLSQVLT 560
V + ++++ L+KL N VV+L + L+ L+E + D ++
Sbjct: 221 VKYVSIEKTA----------LQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMK 270
Query: 561 QRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAV 619
+ + D RY+ ++I + +H I+H D+KP N + M +K+ DFG A +
Sbjct: 271 KYGSL--DETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLL 328
Query: 620 ---------PDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
P++ ++ + +GT Y++PE L ND D+W+ G
Sbjct: 329 NPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELL-------NDSF-----TDYRCDIWAFG 376
Query: 671 CILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNP 730
CIL+QM+ GKPP F+ N Y +K+ Y +F P + D ++ L +N
Sbjct: 377 CILFQMIAGKPP---FKATNE-YLTFQKVMKVQY----AFTPGFPLIIRDLVKKILVKNL 428
Query: 731 ISRVTIDQL 739
R+TI Q+
Sbjct: 429 DRRLTISQI 437
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 87.0 bits (214), Expect = 1e-16
Identities = 54/196 (27%), Positives = 88/196 (44%), Gaps = 26/196 (13%)
Query: 568 DTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVN- 625
D VR++ E++ ++ +H I+H DLKP N +F M +KI DFG A +P VN
Sbjct: 151 DENCVRFYAAEILSSIEYMHSCGIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNS 210
Query: 626 ----IYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKP 681
+ + +GT Y+APE L ++ V K SD+W+ C++YQM+ G P
Sbjct: 211 PDYTTFPSSFVGTAEYVAPELL------------SRQVVSKSSDLWAFACVVYQMIVGSP 258
Query: 682 PYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLS 741
P+ NN IM+ + ++P ++P ++ P R T Q+
Sbjct: 259 PFHGSNPNNIFKKIMSLEYELP--------KLLPPDIVPLFSHLFRIQPSDRSTTQQIKQ 310
Query: 742 GALINPVTVTKFFIHD 757
+T + D
Sbjct: 311 FPFFATITWDNLWTQD 326
>Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 487
Score = 87.0 bits (214), Expect = 1e-16
Identities = 74/294 (25%), Positives = 129/294 (43%), Gaps = 34/294 (11%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEH 553
++ A+K+V ES + EI ++++ ++ VVK + L+++ME CG
Sbjct: 54 QIVAIKQVPV----ESDLQEIIKEISIMQQCDSPH-VVKYYGSYFKNTDLWIVMEYCGAG 108
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIID 612
+S ++ R+K + E Q +K ++ +H +H D+K N + +G K+ D
Sbjct: 109 SVSDIIRLRNKTLTEDEIATI-LQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLAD 167
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG+A + D R+ IGTP +MAPE + + + +D+WS G
Sbjct: 168 FGVAGQLTDTMAK--RNTVIGTPFWMAPEVIQEIGYNC------------VADIWSLGIT 213
Query: 673 LYQMVYGKPPYGTFQGNNRLYAI-MNPDVKIPYPE--KDSFGTVIPRTVIDTIRSCLERN 729
+M GKPPY ++ I NP PE D+F D ++ CL ++
Sbjct: 214 AIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNF--------TDFVKQCLVKS 265
Query: 730 PISRVTIDQLLSGALINPVTVTKFFIHDLIKNAVNYGCDQKHVNNERVEELSED 783
P R T QLL + + DLI A++ ++ V++ E+
Sbjct: 266 PEQRATATQLLQHPFVRSAKGVS-ILRDLINEAMDVKLKRQESQQREVDQDDEE 318
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 87.0 bits (214), Expect = 1e-16
Identities = 77/259 (29%), Positives = 122/259 (46%), Gaps = 43/259 (16%)
Query: 494 HKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDY-HMGQG--------VL 544
HK+ A +V+ D S++D E L KLE + ++VK+ID+ H+ + +L
Sbjct: 35 HKI-AKTKVAIKSIDVSALDR-----ENLIKLEREVKIVKVIDHPHIVKSYEIMRVDNML 88
Query: 545 FLLME-CGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF 603
+++ E C +L + L ++ ++ + R F E V +H IVH DLK N +
Sbjct: 89 YIVSEYCSSGELYETLIEKGRVAENV--ARKWFSETASAVAYLHSQGIVHRDLKAENILL 146
Query: 604 VKGM-LKIIDFGIAN-AVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVG 661
K +KIIDFG +N D +N + G+P Y APE L+ ++ G
Sbjct: 147 GKNSNIKIIDFGFSNFQTGDQLLNTW----CGSPPYAAPELLLGNSYD-----------G 191
Query: 662 KPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDT 721
+D+WS G +LY +V G P+ + N ++++ VKIPY + D
Sbjct: 192 MKADIWSMGVLLYILVAGGFPFPSDSVNKLKRSVLSGLVKIPY--------WVSVECADF 243
Query: 722 IRSCLERNPISRVTIDQLL 740
IR L NP R TI +L
Sbjct: 244 IRKMLVLNPGKRYTIQNVL 262
>7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 520
Score = 87.0 bits (214), Expect = 1e-16
Identities = 79/312 (25%), Positives = 131/312 (41%), Gaps = 35/312 (11%)
Query: 470 TAYEKVELLXXXXXXXXXXXXXXDHKVY-ALKRVSFDEFDESSIDGFKGEIELLKKLENK 528
T +E +E L + Y A+K V ++S + EI LL++L++K
Sbjct: 7 TDFEILEKLGAGSYATVYKARHKKQRTYHAIKYVEMSTLSQTSRENLITEIRLLRELKHK 66
Query: 529 QRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVH 587
+V L D+ +++++E C +LS + + +P T RY +++ V+ +
Sbjct: 67 Y-IVTLQDFFWDDKNIYIVLEYCNAGNLSAFIRTKKALPEST--CRYFLRQLAAAVQYMR 123
Query: 588 DADIVHSDLKPANFVFVKGM----LKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETL 643
D+ H DLKP N + +G LK+ DFG A + +N G+P YMAPE +
Sbjct: 124 ANDVSHFDLKPQNLLLTRGANNVSLKVADFGFAQHLKLGEIN---QQLKGSPLYMAPEIV 180
Query: 644 VAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIP 703
K + +D+WS G ILY+ ++GK PY + L I +
Sbjct: 181 ------------RKHQYDAKADLWSIGVILYECLFGKAPYSSRTIEELLLRIRKAEAITL 228
Query: 704 YPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALIN----PVTVTKFFIHDLI 759
P I D +R L P +R++ + ++ P T DL+
Sbjct: 229 PP-----NARISNECHDLLRRLLAHEPTARISFADFFAHPFLDLKTFPTEHTLQKAIDLV 283
Query: 760 KNAVNYGCDQKH 771
A Y D+KH
Sbjct: 284 TQACAY--DEKH 293
>Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1036
Score = 86.7 bits (213), Expect = 1e-16
Identities = 74/270 (27%), Positives = 126/270 (46%), Gaps = 43/270 (15%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLS 556
A+K ++ +S I K EI++LK+L++ + +V L D +FL+ME C DL+
Sbjct: 37 AIKSINKKNLSKSQILLGK-EIKILKELQH-ENIVALYDVQELPNSVFLVMEYCNGGDLA 94
Query: 557 QVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF---------VKGM 607
L + + DT +R ++ ++++H I+H DLKP N + V G+
Sbjct: 95 DYLQAKGTLSEDT--IRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSSVSGI 152
Query: 608 -LKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDV 666
+KI DFG A + N+ G+P YMAPE +++ ++ +D+
Sbjct: 153 RIKIADFGFARYLHS---NMMAATLCGSPMYMAPEVIMSQHYDAK------------ADL 197
Query: 667 WSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRT----VIDTI 722
WS G ++YQ + GKPP FQ N+ D+++ Y + S IPR + + +
Sbjct: 198 WSIGTVIYQCLVGKPP---FQANS------PQDLRMFYEKNRSLMPSIPRETSPYLANLL 248
Query: 723 RSCLERNPISRVTIDQLLSGALINPVTVTK 752
L+RN R+ + S + V K
Sbjct: 249 LGLLQRNQKDRMDFEAFFSHPFLEQGPVKK 278
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 86.7 bits (213), Expect = 1e-16
Identities = 59/225 (26%), Positives = 109/225 (48%), Gaps = 24/225 (10%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DLSQVLTQRSKIPFDTEFVRYHF 576
EI+ +++L + ++K+ + + ++L+ME +L + +R ++P T R +F
Sbjct: 73 EIDAMRRLRHHPNILKIHEVMATKSKIYLVMELASGGELFSKVLRRGRLPEST--ARRYF 130
Query: 577 QEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYRDNQIGTP 635
Q++ ++ H + H D+KP N + +G LK+ DFG++ A+P+H N GTP
Sbjct: 131 QQLASALRFSHQDGVAHRDVKPQNLLLDEQGNLKVSDFGLS-ALPEHLQNGLLHTACGTP 189
Query: 636 NYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAI 695
Y APE + + DG +A D WSCG IL+ ++ G P+ I
Sbjct: 190 AYTAPEVISRRGY---DGAKA--------DAWSCGVILFVLLVGDVPFDDSNIAAMYRKI 238
Query: 696 MNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
D + P + I + I L+ NP++R++I+ ++
Sbjct: 239 HRRDYRFP--------SWISKQAKSIIYQMLDPNPVTRMSIETVM 275
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 86.3 bits (212), Expect = 2e-16
Identities = 72/234 (30%), Positives = 110/234 (46%), Gaps = 23/234 (9%)
Query: 514 GFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DLSQVLTQRSKIPFDTEFV 572
G + EI ++ KL N V++L D L+L++E E +L +L +R +P + E +
Sbjct: 77 GIEREI-IIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLP-EHEAI 134
Query: 573 RYHFQEMIKCVKVVHDADIVHSDLKPANFVFV-KGMLKIIDFGIANAVPDHTVNIYRDNQ 631
R+ F+++I V H IVH DLKP N + K +KI DFG+A T +
Sbjct: 135 RF-FRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAAL---ETEGKLLETS 190
Query: 632 IGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNR 691
G+P+Y APE + + + G SDVWSCG IL+ ++ G+ P+ GN R
Sbjct: 191 CGSPHYAAPEIVSGIPYQ-----------GFASDVWSCGVILFALLTGRLPFDEEDGNIR 239
Query: 692 LYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALI 745
+ + P D I R D IR L +P R+ +L L+
Sbjct: 240 TLLLKVQKGEFEMPSDDE----ISREAQDLIRKILTVDPERRIKTRDILKHPLL 289
>ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 322
Score = 85.9 bits (211), Expect = 2e-16
Identities = 63/212 (29%), Positives = 106/212 (49%), Gaps = 22/212 (10%)
Query: 496 VYALKRVSFDEFDESSI-DGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEH 553
V+A+K + F E + D + EI +LK++ V KL G + L+ME G
Sbjct: 33 VFAMKMLDFGEILRQRLADQLENEISILKRIYGCPFVAKLYSTDFHGGKVGLIMEYVGGG 92
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIID 612
+L L + + FD + R++ E+I ++ +H I++ DLKP N + G +K+ID
Sbjct: 93 ELFYWLKKCGR--FDEQMARFYAAEIISALRFIHGRGILYRDLKPENILITSTGHIKLID 150
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG + + NIY + GTP YM+PE L R++ + G+ SD W G +
Sbjct: 151 FGFSVYESE---NIYMIS--GTPEYMSPEKL------RSEDD------GRASDYWGLGVM 193
Query: 673 LYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPY 704
+Y+M+ G PP+ + + I+ +V P+
Sbjct: 194 IYEMLCGDPPFYDSSADAIYHKILESNVVFPH 225
>At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 85.5 bits (210), Expect = 3e-16
Identities = 65/242 (26%), Positives = 115/242 (46%), Gaps = 35/242 (14%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLS 556
A+K ++ D ++ + EI +L+++ N +++LID G + L++E C DLS
Sbjct: 39 AIKEIAMDRLNKKLQESLMSEIFILRRI-NHPNIIRLIDMIKSPGKVHLVLEYCKGGDLS 97
Query: 557 QVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM----LKIID 612
+ + +P T ++ Q++ ++V+ D +I+H DLKP N + LKI D
Sbjct: 98 VYVQRHGIVPEAT--AKHFMQQLAAGLQVLRDNNIIHRDLKPQNLLLSTNENDADLKIAD 155
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG A ++ + + G+P YMAPE + + +D+WS G I
Sbjct: 156 FGFARSLQPRGL---AETLCGSPLYMAPEIMQLQKYDAK------------ADLWSVGAI 200
Query: 673 LYQMVYGKPPYGTFQGNNRLYAIMN----PDVKIPYPEKDSFGTVIPRTVIDTIRSCLER 728
L+Q+V G+ P F GN+++ + N ++ P +D + ID + L R
Sbjct: 201 LFQLVTGRTP---FTGNSQIQLLQNIIRSTELHFPGDCRD-----LSLDCIDLCQKLLRR 252
Query: 729 NP 730
NP
Sbjct: 253 NP 254
>7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 338
Score = 85.1 bits (209), Expect = 4e-16
Identities = 69/239 (28%), Positives = 113/239 (46%), Gaps = 33/239 (13%)
Query: 510 SSIDGFKGEIELLKKLE--NKQRVVKLIDYHMGQGV--LFLLMECGEHDLSQVLTQRSKI 565
S +D EI +LKKL+ N ++V+++D + + +F L++ GE VL +
Sbjct: 25 SPLDRVYREIAVLKKLDHPNVVKLVEVLDDPLEDSLYMVFELVKQGE-----VLRIPTDN 79
Query: 566 PFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDFGIANAVPDHTV 624
P + F+E + ++ +H I+H+D+KP N + + G +KI D G+ N
Sbjct: 80 PLSEKRAWSIFRESLLGLEYLHHQKIIHADIKPGNLLLTEFGHVKIADLGVCNEFLGDDA 139
Query: 625 NIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYG 684
I + GTP + APETL+ +N+ G+ +DVW+ G LY +++G P+
Sbjct: 140 TISNGSTAGTPAFRAPETLIP---GQNE------YCGRAADVWALGATLYSLIFGNVPFL 190
Query: 685 TFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSC----LERNPISRVTIDQL 739
I VK P K V + ++SC LE+NP R+TI QL
Sbjct: 191 ADSVPLLYEKIKQDSVKFPENHK----------VTENLKSCIVQMLEKNPTQRITIPQL 239
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 84.7 bits (208), Expect = 5e-16
Identities = 65/249 (26%), Positives = 120/249 (48%), Gaps = 31/249 (12%)
Query: 496 VYALKRVSFDEFDESSIDG-FKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEH 553
+ ALK + E +S I+ + EIE+ L +K +++L + + ++L++E G
Sbjct: 143 IVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN-ILRLYGHFHDEKRIYLILEFAGRG 201
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIID 612
+L Q L + + F E + +M + +H ++H D+KP N + + G +K+ D
Sbjct: 202 ELYQHLRRAKR--FSEEVASKYIFQMANALSYLHKKHVIHRDIKPENILLGIDGEIKLSD 259
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG + P + R GT +Y+ PE + +G++ KV D+WS G +
Sbjct: 260 FGWSVHAPSNR----RTTLCGTLDYLPPEMV--------EGKEHTEKV----DLWSLGVL 303
Query: 673 LYQMVYGKPPYGTFQGNNRLY-AIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPI 731
Y+ + G PP+ G++ Y I D+KIP + +P D I L+ NP
Sbjct: 304 TYEFLVGAPPFEDMSGHSATYKRIAKVDLKIP--------SFVPPDARDLISRLLQHNPE 355
Query: 732 SRVTIDQLL 740
R++++Q++
Sbjct: 356 KRMSLEQVM 364
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 84.3 bits (207), Expect = 6e-16
Identities = 70/246 (28%), Positives = 117/246 (47%), Gaps = 24/246 (9%)
Query: 500 KRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFL---LMECGEHDLS 556
+R+S ++ +E + + E +L+++ ++ LID + +FL LM GE L
Sbjct: 60 ERLSPEQLEEVR-EATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGE--LF 116
Query: 557 QVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGI 615
LT+ K+ + R + +++ V +H +IVH DLKP N + M +++ DFG
Sbjct: 117 DYLTE--KVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGF 174
Query: 616 A-NAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILY 674
+ + P + GTP Y+APE L + G GK D+W+CG IL+
Sbjct: 175 SCHLEPGEKLR----ELCGTPGYLAPEILKCSMDETHPG------YGKEVDLWACGVILF 224
Query: 675 QMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRV 734
++ G PP+ + L IM + PE D + TV D I L+ +P +R+
Sbjct: 225 TLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSS----TVKDLISRLLQVDPEARL 280
Query: 735 TIDQLL 740
T +Q L
Sbjct: 281 TAEQAL 286
>At4g08500 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 84.0 bits (206), Expect = 8e-16
Identities = 82/301 (27%), Positives = 132/301 (43%), Gaps = 31/301 (10%)
Query: 447 NYNGSFDTKKRTSYAVPTITVNGTAYEKVELLXXXXXXXXXXXXXXDHKVYALKRVSFDE 506
N S T TS P T+++K +LL D +A+K VS
Sbjct: 308 NEGDSSSTVSNTSPIYPDGGAIITSWQKGQLLGRGSFGSVYEGISGDGDFFAVKEVSL-- 365
Query: 507 FDESS-----IDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQ 561
D+ S I +GEI+LL +L++ Q +V+ L++ +E L Q
Sbjct: 366 LDQGSQAQECIQQLEGEIKLLSQLQH-QNIVRYRGTAKDGSNLYIFLELVTQGSLLKLYQ 424
Query: 562 RSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANF-VFVKGMLKIIDFGIANAVP 620
R ++ V + ++++ +K +HD +H D+K AN V G +K+ DFG+A
Sbjct: 425 RYQLR--DSVVSLYTRQILDGLKYLHDKGFIHRDIKCANILVDANGAVKLADFGLAKVSK 482
Query: 621 DHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGK 680
+ + + GTP +MAPE + N +DG G P+D+WS GC + +M G+
Sbjct: 483 FNDIKSCK----GTPFWMAPEVI---NRKDSDG------YGSPADIWSLGCTVLEMCTGQ 529
Query: 681 PPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
PY + L+ I + PE ++ R I CL+ NP R T +LL
Sbjct: 530 IPYSDLEPVQALFRIGRGTL----PEVPDTLSLDARLF---ILKCLKVNPEERPTAAELL 582
Query: 741 S 741
+
Sbjct: 583 N 583
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 83.6 bits (205), Expect = 1e-15
Identities = 68/245 (27%), Positives = 113/245 (45%), Gaps = 27/245 (11%)
Query: 498 ALKRVSFDEFDESSIDG-FKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLS 556
ALK ++ +S + G + EI L+ L + ++KL D + + +++E ++L
Sbjct: 82 ALKIINKKVLAKSDMQGRIEREISYLRLLRHPH-IIKLYDVIKSKDEIIMVIEYAGNELF 140
Query: 557 QVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGI 615
+ QR K+ + R FQ++I V+ H IVH DLKP N + + + +KI DFG+
Sbjct: 141 DYIVQRDKM--SEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGL 198
Query: 616 ANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQ 675
+N + D + G+PNY APE + K G DVWSCG ILY
Sbjct: 199 SNIMTDGN---FLKTSCGSPNYAAPEVI-----------SGKLYAGPEVDVWSCGVILYV 244
Query: 676 MVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVT 735
M+ + P+ I N +P +I R +I NP++R++
Sbjct: 245 MLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLI--------VNPLNRIS 296
Query: 736 IDQLL 740
I +++
Sbjct: 297 IHEIM 301
>YAR019c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 974
Score = 83.2 bits (204), Expect = 1e-15
Identities = 72/254 (28%), Positives = 113/254 (44%), Gaps = 31/254 (12%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEH 553
+V A+K V ++ +E ++ EI LLK L N +VK + L++L+E C
Sbjct: 49 QVVAIKEVVYENDEE--LNDIMAEISLLKNL-NHNNIVKYHGFIRKSYELYILLEYCANG 105
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIID 612
L +++++ S + E Y Q ++ +K +H ++H D+K AN + +K+ D
Sbjct: 106 SLRRLISRSSTGLSENESKTYVTQTLLG-LKYLHGEGVIHRDIKAANILLSADNTVKLAD 164
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG++ V + + GT N+MAPE L N G SD+WS G
Sbjct: 165 FGVSTIVNSSALTL-----AGTLNWMAPEIL------GNRGASTL------SDIWSLGAT 207
Query: 673 LYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPIS 732
+ +M+ PPY N YA+ N Y SF + D + C +N
Sbjct: 208 VVEMLTKNPPYHNLTDANIYYAVEND----TYYPPSSFSEPLK----DFLSKCFVKNMYK 259
Query: 733 RVTIDQLLSGALIN 746
R T DQLL IN
Sbjct: 260 RPTADQLLKHVWIN 273
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 83.2 bits (204), Expect = 1e-15
Identities = 64/236 (27%), Positives = 108/236 (45%), Gaps = 24/236 (10%)
Query: 507 FDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMEC-GEHDLSQVLTQRSKI 565
F ++ K EI +K +++ VV++I+ + +++++E +L + Q+ ++
Sbjct: 56 FRHKMVEQLKREISTMKLIKHPN-VVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRL 114
Query: 566 PFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTV 624
D R +FQ++I V H + H DLKP N + G+LK+ DFG++
Sbjct: 115 KEDE--ARRYFQQLINAVDYCHSRGVYHRDLKPENLILDANGVLKVSDFGLSAFSRQVRE 172
Query: 625 NIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYG 684
+ GTPNY+APE L + G +DVWSCG IL+ ++ G P+
Sbjct: 173 DGLLHTACGTPNYVAPEVLSDKGYD-----------GAAADVWSCGVILFVLMAGYLPF- 220
Query: 685 TFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
L + K + F R I+ LE NPI+R++I +LL
Sbjct: 221 ---DEPNLMTLYKRICKAEFSCPPWFSQGAKR----VIKRILEPNPITRISIAELL 269
>At5g28290 [R] KOG0589 Serine/threonine protein kinase
Length = 568
Score = 82.8 bits (203), Expect = 2e-15
Identities = 63/258 (24%), Positives = 118/258 (45%), Gaps = 26/258 (10%)
Query: 493 DHKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQG--VLFLLMEC 550
+ K+Y LK++ + E+EL+ K+ N +V+ D + +G V ++ C
Sbjct: 26 EKKLYVLKKIRLARQTGRTRRSAHQEMELISKIRNPF-IVEYKDSWVEKGCYVCIVIGYC 84
Query: 551 GEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LK 609
D+++ + + + + F E + +++ ++ +H + I+H D+K +N K ++
Sbjct: 85 KGGDMAEAIKKANGVEFSEEKLCKWLVQLLMALEYLHASHILHRDVKCSNIFLTKDQDIR 144
Query: 610 IIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
+ DFG+A + T + + +GTP+YM PE L + + G SD+WS
Sbjct: 145 LGDFGLAKIL---TSDDLASSVVGTPSYMCPELLADIPY------------GSKSDIWSL 189
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
GC +Y+M KP + F + I N + P P + S ++S L +N
Sbjct: 190 GCCMYEMTALKPAFKAFDMQGLINRI-NRSIVAPLPAQYS------TAFRSLVKSMLRKN 242
Query: 730 PISRVTIDQLLSGALINP 747
P R + LL L+ P
Sbjct: 243 PELRPSASDLLRQPLLQP 260
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 82.4 bits (202), Expect = 2e-15
Identities = 59/215 (27%), Positives = 100/215 (46%), Gaps = 23/215 (10%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQ 577
E++LLK L ++ + + ++ + E DL ++L R P + +FV+Y
Sbjct: 70 ELKLLKHLRHENLICLQDIFLSPLEDIYFVTELQGTDLHRLLQTR---PLEKQFVQYFLY 126
Query: 578 EMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVNIYRDNQIGTPN 636
++++ +K VH A ++H DLKP+N + + LKI DFG+A + D + Y + T
Sbjct: 127 QILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR-IQDPQMTGY----VSTRY 181
Query: 637 YMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIM 696
Y APE ++ K D+WS GCI +M+ GKP F G + ++
Sbjct: 182 YRAPEIMLTWQ-----------KYDVEVDIWSAGCIFAEMIEGKP---LFPGKDHVHQFS 227
Query: 697 NPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPI 731
+ P KD T+ + + S R+PI
Sbjct: 228 IITDLLGSPPKDVINTICSENTLKFVTSLPHRDPI 262
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 82.4 bits (202), Expect = 2e-15
Identities = 66/248 (26%), Positives = 111/248 (44%), Gaps = 17/248 (6%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH- 553
K+ +++ ++ + + F+ EI++LK L + VV+ + LF++ME E
Sbjct: 196 KIINKRKILLTSSEKRATEMFQREIDILKSLHHPG-VVQCHEIFENDDELFIVMEYVEGG 254
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIID 612
DL L I D + + +++++ + +H + H D+KP N + LKI D
Sbjct: 255 DLMDFLIANGSI--DEQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISD 312
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG+A + H + + GT Y+APE L + N + G K D+WS GC+
Sbjct: 313 FGLAKVI--HGTGTFLETFCGTMGYLAPEVLKSKNVNLDGGYDDK------VDIWSLGCV 364
Query: 673 LYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPIS 732
LY M+ P+ + + I K YP + I ID I LE NP
Sbjct: 365 LYVMLTASIPFASSSQAKCIELIS----KGAYPIEPLLENEISEEGIDLINRMLEINPEK 420
Query: 733 RVTIDQLL 740
R++ + L
Sbjct: 421 RISESEAL 428
>Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neurofibromin
Length = 445
Score = 82.4 bits (202), Expect = 2e-15
Identities = 72/266 (27%), Positives = 120/266 (45%), Gaps = 37/266 (13%)
Query: 493 DHKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQG--VLFLLME- 549
D K+ K + + E+ E+ LL++L++ +V+ D + + L+++ME
Sbjct: 30 DGKILVWKELDYGSMTEAEKQMLVSEVNLLRELKHPN-IVRYYDRIIDRTNTTLYIVMEY 88
Query: 550 CGEHDLSQVLTQRSKIP--FDTEFVRYHFQEMIKCVKVVHDAD-----IVHSDLKPANFV 602
C DL+ V+T+ +K D EFV ++ +K H ++H DLKPAN V
Sbjct: 89 CEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPAN-V 147
Query: 603 FVKGM--LKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKV 660
F+ G +K+ DFG+A + T + +GTP YM+PE + M++
Sbjct: 148 FLDGKQNVKLGDFGLARILNHDTS--FAKTFVGTPYYMSPEQMNRMSYNEK--------- 196
Query: 661 GKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDV-KIPYPEKDSFGTVIPRTVI 719
SD+WS GC+LY++ PP+ F I +IPY D +I R
Sbjct: 197 ---SDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIPYRYSDELNEIITR--- 250
Query: 720 DTIRSCLERNPISRVTIDQLLSGALI 745
L R +++++L LI
Sbjct: 251 -----MLNLKDYHRPSVEEILENPLI 271
>Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 313
Score = 82.4 bits (202), Expect = 2e-15
Identities = 65/220 (29%), Positives = 109/220 (49%), Gaps = 26/220 (11%)
Query: 493 DHKVYALKRVS-FDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECG 551
D K ALK+V F+ D + EI LLK+L N ++K +D + L +++E
Sbjct: 67 DRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQL-NHPNIIKYLDSFIEDNELNIVLELA 125
Query: 552 EH-DLSQVLT----QRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPAN-FVFVK 605
+ DLSQ++ Q+ IP T V +F ++ V+ +H ++H D+KPAN F+
Sbjct: 126 DAGDLSQMIKYFKKQKRLIPERT--VWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITAT 183
Query: 606 GMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSD 665
G++K+ D G+ T + + +GTP YM+PE + +G K SD
Sbjct: 184 GVVKLGDLGLGRFFSSETTAAH--SLVGTPYYMSPERI------HENGYNFK------SD 229
Query: 666 VWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYP 705
+WS GC+LY+M + P+ + L+++ + YP
Sbjct: 230 IWSLGCLLYEMAALQSPF--YGDKMNLFSLCQKIEQCDYP 267
>7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 735
Score = 82.0 bits (201), Expect = 3e-15
Identities = 55/201 (27%), Positives = 109/201 (53%), Gaps = 29/201 (14%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGV--LFLLMEC-G 551
+++A K +++DE DE+ D EI +L++L++ +V+ + + + ++++MEC
Sbjct: 43 ELFAWKGMNYDELDEAKCDALVSEISVLRQLQHPN-IVQYYHHLVNREAKSVYIVMECCA 101
Query: 552 EHDLSQVL----TQRSKIPFDTEFVRYHFQEMIKCVKVVHD----ADIVHSDLKPAN-FV 602
DL+Q++ +QR + F+ ++ ++ + ++V H+ I+H D+KPAN F+
Sbjct: 102 GGDLAQIVQRARSQRQR--FEEPYIWRVLFQLCRALQVCHNKIPNGTILHRDIKPANIFL 159
Query: 603 FVKGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGK 662
G K+ DFG+A + + + +GTP+YM+PE + + R
Sbjct: 160 DAAGNAKLGDFGLARML--RRDQSFAASFVGTPHYMSPELVKGRKYDRK----------- 206
Query: 663 PSDVWSCGCILYQMVYGKPPY 683
SDVW+ GC++Y+M +PP+
Sbjct: 207 -SDVWAVGCLVYEMCALRPPF 226
>Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1050
Score = 81.6 bits (200), Expect = 4e-15
Identities = 65/236 (27%), Positives = 112/236 (46%), Gaps = 42/236 (17%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTEFVRYHF 576
EI++LK+L++ + +V L D+ ++L+ME C DL+ L + DT +R
Sbjct: 63 EIKILKELKH-ENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDT--IRLFL 119
Query: 577 QEMIKCVKVVHDADIVHSDLKPANFVFVKG----------MLKIIDFGIANAVPDHTVNI 626
Q++ ++++H I+H DLKP N + +KI DFG A + N+
Sbjct: 120 QQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQS---NM 176
Query: 627 YRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTF 686
G+P YMAPE +++ ++ DG+ +D+WS G I+YQ + GK P+
Sbjct: 177 MAATLCGSPMYMAPEVIMSQHY---DGK---------ADLWSIGTIVYQCLTGKAPF--- 221
Query: 687 QGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIR----SCLERNPISRVTIDQ 738
A D+++ Y + + IPR +R + L+RN R+ D+
Sbjct: 222 ------QASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDE 271
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 81.3 bits (199), Expect = 5e-15
Identities = 62/254 (24%), Positives = 120/254 (46%), Gaps = 27/254 (10%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLS 556
A+K V+ ++ ES + + EI ++K +E+ V+ L D + + L+LL+E +L
Sbjct: 74 AIKIVNKEKLSESVLQKVEREIAIMKLIEHPH-VLHLYDVYENKKYLYLLLEHVSGGELF 132
Query: 557 QVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGI 615
L ++ ++ ++ R F+++I + H +I H DLKP N + + +K+ DFG+
Sbjct: 133 DYLVRKGRLM--SKEARKFFRQIISALDFCHAHNICHRDLKPENLLLDERNNIKVADFGM 190
Query: 616 ANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQ 675
A+ + ++ + G+P+Y PE + + G+ +DVWSCG ILY
Sbjct: 191 ASLQVEGSM---LETSCGSPHYACPEVIRGEKYD-----------GRKADVWSCGVILYA 236
Query: 676 MVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVT 735
++ G P+ N L + IP+ +P V +R+ +E +P R +
Sbjct: 237 LLVGALPFDDDNLRNLLEKVKRGVFHIPH--------FVPADVQSLLRAMIEVDPGKRYS 288
Query: 736 IDQLLSGALINPVT 749
+ + ++ T
Sbjct: 289 LADVFKHPWVSGTT 302
>At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 81.3 bits (199), Expect = 5e-15
Identities = 68/255 (26%), Positives = 119/255 (46%), Gaps = 38/255 (14%)
Query: 497 YALKRVSFDEFD-ESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHD 554
YA K + + + E ++ + EIE++K L + V+ + + + ++ME C +
Sbjct: 158 YACKSIPKRKLENEEDVEDVRREIEIMKHLLGQPNVISIKGAYEDSVAVHMVMELCRGGE 217
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIK-CVKVVHDADIVHSDLKPANFVFVK----GMLK 609
L + +R +E H ++I V+ H ++H DLKP NF+FV LK
Sbjct: 218 LFDRIVERGHY---SERKAAHLAKVILGVVQTCHSLGVMHRDLKPENFLFVNDDEDSPLK 274
Query: 610 IIDFGIANAV-PDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWS 668
IDFG++ + P + +G+P Y+APE L +N G +A D+WS
Sbjct: 275 AIDFGLSMFLKPGENFT----DVVGSPYYIAPEVL-----NKNYGPEA--------DIWS 317
Query: 669 CGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKI---PYPEKDSFGTVIPRTVIDTIRSC 725
G ++Y ++ G P+ ++ ++ + P+P+ + + D IR
Sbjct: 318 AGVMIYVLLSGSAPFWGETEEEIFNEVLEGELDLTSDPWPQ-------VSESAKDLIRKM 370
Query: 726 LERNPISRVTIDQLL 740
LERNPI R+T Q+L
Sbjct: 371 LERNPIQRLTAQQVL 385
>CE15235 [R] KOG0589 Serine/threonine protein kinase
Length = 357
Score = 80.9 bits (198), Expect = 7e-15
Identities = 67/268 (25%), Positives = 124/268 (46%), Gaps = 33/268 (12%)
Query: 494 HKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH 553
H+ +K ++ E + + E+ LLKK+++ ++ ID + L ++M+ E
Sbjct: 29 HQKVIIKLINTHGMTEKEENSIQSEVNLLKKVQHPL-IIGYIDSFIMDNQLGIVMQYAEG 87
Query: 554 DLSQVLTQRSKIPFDTEFVRY--------HFQEMIKCVKVVHDADIVHSDLKPANFVF-- 603
+ L + D+ Y +F +++ + +H +IVH DLKP N +
Sbjct: 88 GTLERLINDQRAIKDSNMREYFPEKTVLDYFTQILIALNHMHQKNIVHRDLKPQNILMNR 147
Query: 604 VKGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKP 663
K +LK+ DFGI+ + + IGTPNY++PE + + +
Sbjct: 148 RKTVLKLSDFGISKELGTKSA---ASTVIGTPNYLSPEICESRPYNQK------------ 192
Query: 664 SDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIR 723
SD+WS GC+LY+++ + F G N L AI+ +KI +++ G + V +
Sbjct: 193 SDMWSLGCVLYELLQLE---RAFDGEN-LPAIV---MKITRSKQNPLGDHVSNDVKMLVE 245
Query: 724 SCLERNPISRVTIDQLLSGALINPVTVT 751
+ L+ + R + QLLS L+ P ++
Sbjct: 246 NLLKTHTDKRPDVSQLLSDPLVLPYLIS 273
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 80.9 bits (198), Expect = 7e-15
Identities = 63/233 (27%), Positives = 107/233 (45%), Gaps = 27/233 (11%)
Query: 511 SIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMEC-GEHDLSQVLTQRSKIPFDT 569
+++ + EI+ L+KL + + +L +FL+ME +L +T++ +P
Sbjct: 65 TVNKTRNEIDNLQKLTHPH-ITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRE 123
Query: 570 EFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYR 628
R +FQ++I V H+ IVH DLKP N + +KI DFG++N + D +
Sbjct: 124 S--RRYFQQIISGVSYCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNYMTDGDL---L 178
Query: 629 DNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQG 688
G+PNY APE + K VG D+WSCG ILY M+ G P+
Sbjct: 179 STACGSPNYAAPELI-----------SNKLYVGPEVDLWSCGVILYAMLCGTLPFDDQNV 227
Query: 689 NNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLS 741
I + +PY + + D I + L+ +P+ R + ++++
Sbjct: 228 PTLFAKIKSGRYTVPYS--------MEKQAADLISTMLQVDPVKRADVKRIVN 272
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 80.9 bits (198), Expect = 7e-15
Identities = 71/271 (26%), Positives = 111/271 (40%), Gaps = 54/271 (19%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQ 577
E++ L+KL N ++KL + LF + EC +H+L ++ +R + PF +R
Sbjct: 58 EVKALRKL-NHPHIIKLKEIVREHNELFFIFECMDHNLYHIMKERER-PFSEGEIRSFMS 115
Query: 578 EMIKCVKVVHDADIVHSDLKPANFVFVKGMLKIIDFGIANAV---PDHTVNIYRDNQIGT 634
+M++ + +H H DLKP N + +LKI DFG+A V P +T + T
Sbjct: 116 QMLQGLAHMHKNGYFHRDLKPENLLVTNNILKIADFGLAREVASMPPYT------EYVST 169
Query: 635 PNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQM------------------ 676
Y APE L+ + D+W+ G IL ++
Sbjct: 170 RWYRAPEVLLQSSL-----------YTPAVDMWAVGAILAELYALTPLFPGESEIDQLYK 218
Query: 677 ---VYGKPPYGTFQGNNRLYAIMN------PDVKIPYPEKDSFGTVIPRTVIDTIRSCLE 727
V GKP + TF + IM+ P +I D P ID I
Sbjct: 219 ICCVLGKPDWTTFPEAKSISRIMSISHTEFPQTRI----ADLLPNAAPE-AIDLINRLCS 273
Query: 728 RNPISRVTIDQLLSGALINPVTVTKFFIHDL 758
+P+ R T D+ L+ + T + IHDL
Sbjct: 274 WDPLKRPTADEALNHPFFSMATQASYPIHDL 304
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 80.9 bits (198), Expect = 7e-15
Identities = 62/247 (25%), Positives = 115/247 (46%), Gaps = 27/247 (10%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEH 553
K A+K ++ ++ ES + + EI ++K +++ V+ L D + + L+L++E
Sbjct: 42 KKVAIKIINREKLSESVLMKVEREIAIMKLIDHPH-VLGLSDVYENKKYLYLILEHVSGG 100
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIID 612
+L L ++ ++ + R F+++I + H I H DLKP N + K +KI D
Sbjct: 101 ELFDYLVKKGRLT--PKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIKIAD 158
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG+A+ P ++ + G+P+Y PE + + G+ +DVWSCG I
Sbjct: 159 FGMASLQPAGSM---LETSCGSPHYACPEVIRGEKYD-----------GRKADVWSCGVI 204
Query: 673 LYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPIS 732
LY ++ G P+ L + IP+ +P +R +E NP
Sbjct: 205 LYALLVGALPFDDDNLRQLLEKVKRGVFHIPH--------FVPPDCQSLLRGMIEVNPDR 256
Query: 733 RVTIDQL 739
R+T+ ++
Sbjct: 257 RLTLAEI 263
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 80.9 bits (198), Expect = 7e-15
Identities = 74/268 (27%), Positives = 123/268 (45%), Gaps = 35/268 (13%)
Query: 498 ALKRVSFDEF-DESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVL--FLLMECGEHD 554
ALK+V FD F DE+ E+ L+ +V+L+D L +L+ E E D
Sbjct: 52 ALKKV-FDAFRDETDAQRTYREVIFLRAFRCHPNIVRLVDIFKASNNLDFYLVFEFMESD 110
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDF 613
L V+ +R + D R+ ++I +K +H +++H DLKP+N + K LK+ DF
Sbjct: 111 LHNVI-KRGNVLKDVH-KRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADF 168
Query: 614 GIANAVPDHTVNIYRD--------NQIGTPNYMAPETLVA-MNFTRNDGEQAKWKVGKPS 664
G+A + IY D + + T Y APE LVA N+T K
Sbjct: 169 GLARTLSSR--RIYDDLEQDGMLTDYVATRWYRAPEILVASRNYT------------KGI 214
Query: 665 DVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRS 724
D+W GCIL +M+ KP FQG + + I +P K ++ P +
Sbjct: 215 DMWGLGCILGEMIRQKP---LFQGTSTVNQIEKIVTSLPNVTKLDIASIGPSFGSVLLSR 271
Query: 725 CLERNPISRVTIDQLLSGALINPVTVTK 752
++R+ R ++D+++ + +++ K
Sbjct: 272 NIQRD--RRYSLDEMMKNCCDDGISLVK 297
>Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase
Length = 330
Score = 80.9 bits (198), Expect = 7e-15
Identities = 65/256 (25%), Positives = 118/256 (45%), Gaps = 24/256 (9%)
Query: 493 DHKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CG 551
D + K V E EI +L L++ ++ ++ M L + +E C
Sbjct: 74 DDSLVVWKEVDLTRLSEKERRDALNEIVILALLQH-DNIIAYYNHFMDNTTLLIELEYCN 132
Query: 552 EHDL-SQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLK 609
+L ++L Q+ K+ F+ E V ++ +++ V +H A I+H D+K N K ++K
Sbjct: 133 GGNLYDKILRQKDKL-FEEEMVVWYLFQIVSAVSCIHKAGILHRDIKTLNIFLTKANLIK 191
Query: 610 IIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
+ D+G+A + ++ + +GTP YM+PE + K SD+W+
Sbjct: 192 LGDYGLAKKL--NSEYSMAETLVGTPYYMSPELCQGV------------KYNFKSDIWAV 237
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
GC++++++ K TF N L + I E DS + +I + SCL+++
Sbjct: 238 GCVIFELLTLK---RTFDATNPLNLCVKIVQGIRAMEVDS--SQYSLELIQMVHSCLDQD 292
Query: 730 PISRVTIDQLLSGALI 745
P R T D+LL L+
Sbjct: 293 PEQRPTADELLDRPLL 308
>SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 830
Score = 80.5 bits (197), Expect = 9e-15
Identities = 80/311 (25%), Positives = 133/311 (42%), Gaps = 64/311 (20%)
Query: 494 HKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGE 552
++V ++K V + + ++ + EI +LK++ + VV+LID + L+ME C
Sbjct: 37 NRVISIKSVLTKKLTKKLLENLESEISILKEIRHVH-VVELIDCIKAGRFIHLVMEYCSL 95
Query: 553 HDLSQVLTQRSK---IP----------------FDTEFVRYHFQEMIKCVKVVHDADIVH 593
DLS + +R K IP + VR+ Q++ ++ + ++H
Sbjct: 96 GDLSYFIRKREKFNSIPSLAWINIDHPPVYKAGLNETLVRHFTQQLASALQFLRSRSLIH 155
Query: 594 SDLKPANFV---------------FVKG----MLKIIDFGIANAVPDHTVNIYRDNQIGT 634
D+KP N + FV MLK+ DFG A + ++ + G+
Sbjct: 156 RDVKPQNLLLQPPPTAAYLEEHPQFVGSPKLPMLKLADFGFARYLQTSSM---AETLCGS 212
Query: 635 PNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYA 694
P YMAPE L R + AK +D+WS G +LY+M GKPP+ L
Sbjct: 213 PLYMAPEIL------RYEKYDAK------ADLWSVGAVLYEMAVGKPPFKAPNHVELLRR 260
Query: 695 IMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALI-----NPVT 749
I I +PE+ I + I + L++NP R+ D S ++ + T
Sbjct: 261 IQKAKDVIKFPEE----AFIHPDIKTLICALLKQNPADRIDYDGFFSSIVVTTPLDDAST 316
Query: 750 VTKFFIHDLIK 760
+T I D +K
Sbjct: 317 LTGSDIQDAVK 327
>SPCC1919.01 [T] KOG0583 Serine/threonine protein kinase
Length = 203
Score = 80.5 bits (197), Expect = 9e-15
Identities = 54/176 (30%), Positives = 84/176 (47%), Gaps = 21/176 (11%)
Query: 566 PFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDFGIANAVPDHTV 624
P E R F++++ V +H ++H D+KP N +F + L +IDFG+A +P
Sbjct: 20 PMPLETCRKSFRQLVLAVNYIHGKGVIHRDIKPDNILFKENNNLCVIDFGLAEFLPK--- 76
Query: 625 NIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYG 684
+ + GTP +MAPE D E K K GKP D+WS G LY + + + P+
Sbjct: 77 DGFVKPASGTPAFMAPELF--------DNELKKIK-GKPLDIWSMGVTLYVIAFAEFPFN 127
Query: 685 TFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
+ + I + IP ++ R CLE+NP R+TI++LL
Sbjct: 128 GSTILDMINVIKGKSLMIPAYCNSDLRKLLER--------CLEKNPEKRITIEELL 175
>Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 607
Score = 80.5 bits (197), Expect = 9e-15
Identities = 60/224 (26%), Positives = 98/224 (42%), Gaps = 25/224 (11%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQ 577
EIEL + L+++ V + + L C L+ + R + + E VRY+ +
Sbjct: 71 EIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTL-LEPE-VRYYLR 128
Query: 578 EMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVNIYRDNQIGTPN 636
+++ +K +H I+H DLK NF + M LK+ DFG+A + + GTPN
Sbjct: 129 QILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQR--KKTICGTPN 186
Query: 637 YMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIM 696
Y+APE L+ G +DVWS GC++Y ++ G PP+ T I
Sbjct: 187 YVAPEVLLRQGH------------GPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIK 234
Query: 697 NPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
+P + + + L +P R +IDQ+L
Sbjct: 235 QVHYTLP--------ASLSLPARQLLAAILRASPRDRPSIDQIL 270
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 80.5 bits (197), Expect = 9e-15
Identities = 65/274 (23%), Positives = 125/274 (44%), Gaps = 42/274 (15%)
Query: 494 HKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH 553
H++ A+K+ E +E + E+++L+ L+ ++ +V+L + +G L+L+ E E
Sbjct: 36 HEIVAIKKFKDSEENEEVKETTLRELKMLRTLK-QENIVELKEAFRRRGKLYLVFEYVEK 94
Query: 554 DLSQVLTQRSK-IPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFV-KGMLKII 611
++ ++L + +P E V+ + ++IK + H DIVH D+KP N + +LK+
Sbjct: 95 NMLELLEEMPNGVP--PEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLC 152
Query: 612 DFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGC 671
DFG A + + N + T Y +PE L+ + GK D+WS GC
Sbjct: 153 DFGFARNLSEGN-NANYTEYVATRWYRSPELLLGAPY------------GKSVDMWSVGC 199
Query: 672 ILYQMVYGKPPY------------------------GTFQGNNRLYAIMNPDVKIPYPEK 707
IL ++ G+P + F N R + + P V P +
Sbjct: 200 ILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLE 259
Query: 708 DSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLS 741
+ ++ ++D +++ L+ +P R +Q L+
Sbjct: 260 RRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLN 293
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 80.5 bits (197), Expect = 9e-15
Identities = 57/192 (29%), Positives = 97/192 (49%), Gaps = 21/192 (10%)
Query: 493 DHKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGE 552
D V+A+K++ D + EI+L K + NK ++ L + +G +F+++E
Sbjct: 26 DGAVFAIKKMPVDRETGFPFTAIR-EIKLCKSVINKH-IIGLDEIVFEEGFIFVVLEYMP 83
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKII 611
+DL+ +L +K+ T+ +R ++I+ V +H +VH D+KP+N + GMLK+
Sbjct: 84 YDLTGLLASGAKL--STDQIRSITSQLIEAVSSMHGMGLVHRDIKPSNILLDCHGMLKLT 141
Query: 612 DFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGC 671
DFG+ + N ++ T Y APE L+ GE + D WS GC
Sbjct: 142 DFGLTREISGMMTN-----RVCTLWYRAPELLL--------GETS---YSLKVDAWSVGC 185
Query: 672 ILYQMVYGKPPY 683
I+ +M G+PPY
Sbjct: 186 IMLEMRLGRPPY 197
>ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 488
Score = 80.5 bits (197), Expect = 9e-15
Identities = 74/285 (25%), Positives = 130/285 (44%), Gaps = 29/285 (10%)
Query: 497 YALKRVSFDEFDESSI-DGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDL 555
YA+K V + + + + EI + KL+N VVK+ +F+++E E
Sbjct: 65 YAMKVVRLKDIKSRKVHEKLESEIAIHSKLDNPN-VVKMYRSFRSSEYVFMVLELCERGA 123
Query: 556 SQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLKIIDFG 614
L +R+ + R+ Q + + + + +VH DLK N F+ K +KI DFG
Sbjct: 124 LDALLKRNGKLKERHVARFVKQTVEGLIYLHNSVSVVHRDLKLGNLFLDSKFNVKIGDFG 183
Query: 615 IANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILY 674
++ + D + GTPNY+APE L F + G + +D+WS G I+Y
Sbjct: 184 LSAVIKDGEKKV---TMCGTPNYIAPEVL----FGKASGHSFE------ADIWSLGVIIY 230
Query: 675 QMVYGKPPYGTFQGNN--RLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPIS 732
++ G PP FQ N +Y ++ + I +PE + ID I L NP+
Sbjct: 231 TLLVGVPP---FQKKNVEDIYKMIKLNNYI-FPENCDLSS----EAIDLITQILNTNPLE 282
Query: 733 RVTIDQLLSGALINPVTVTKFFIHDLIKNAVNYGCDQKHVNNERV 777
R T++ +LS ++ + F+ + +N + ++ V+ + V
Sbjct: 283 RPTLEHILSHKFLSK---KEHFLMKIYRNLMTNRTEEGVVDTDYV 324
>CE23001 [R] KOG0589 Serine/threonine protein kinase
Length = 579
Score = 80.5 bits (197), Expect = 9e-15
Identities = 66/250 (26%), Positives = 114/250 (45%), Gaps = 23/250 (9%)
Query: 493 DHKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGE 552
D + +K ++ + D S E+ LL ++E+ ++ D +GVL + ME +
Sbjct: 193 DSSLVIIKEINMYDLDSSQRRLALNEVSLLSRIEHPN-IIAYYDSFEEEGVLMIEMEYAD 251
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLKII 611
+ R++ D E + +M V +H+ ++H DLK AN F+ +KI
Sbjct: 252 GGTLAQMLSRTQNLLDEEQIGDMMIQMCSAVAYLHENSVLHRDLKTANVFLTRDSFVKIG 311
Query: 612 DFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGC 671
DFGI+ + T+ +GTP Y++PE +++ + SD+W+ GC
Sbjct: 312 DFGISKIMGTETLAQGAKTVVGTPYYISPEMCSGVSY------------NEKSDMWALGC 359
Query: 672 ILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPY-PEKDSFGTVIPRTVIDTIRSCLERNP 730
ILY+M K F+G+N L A++N + Y P K + + IR L+ +P
Sbjct: 360 ILYEMCCLKK---AFEGDN-LPALVNSIMTCAYTPVKGPYSAEMKM----VIRELLQLDP 411
Query: 731 ISRVTIDQLL 740
R + Q L
Sbjct: 412 QKRPSAPQAL 421
>CE08098 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1173
Score = 80.5 bits (197), Expect = 9e-15
Identities = 66/266 (24%), Positives = 125/266 (46%), Gaps = 29/266 (10%)
Query: 496 VYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHD 554
VYA+K ++ D+ + + F E + N + +V+L L+++ME D
Sbjct: 93 VYAMKMLNKDDMIKRADSAFFWEERDIMAHANSEWIVRLQYAFQDPRHLYMVMEYMPGGD 152
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDF 613
L ++T ++ R++ E+++ + +H +H D+KP N + + G +K+ DF
Sbjct: 153 LVNLMTSYE---VSEKWTRFYTAEIVEALAALHSMGYIHRDVKPDNMLISISGHIKLADF 209
Query: 614 GIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCIL 673
G + + V + +GTP+Y++PE L RN G+ A++ GK D WS G +
Sbjct: 210 GTCVKMNANGV-VRCSTAVGTPDYISPEVL------RNQGQDAEF--GKEVDWWSVGVFI 260
Query: 674 YQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNP--I 731
Y+M+ G+ P+ + IMN + +P++ +I D I+ L P +
Sbjct: 261 YEMLVGETPFYAEALVSTYTNIMNHKTSLKFPDE----PLISTQAKDIIKKFLSAAPDRL 316
Query: 732 SRVTIDQLLSGALINPVTVTKFFIHD 757
R ++D + + KFF++D
Sbjct: 317 GRNSVDDIRN---------HKFFVND 333
>At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 554
Score = 80.5 bits (197), Expect = 9e-15
Identities = 65/249 (26%), Positives = 112/249 (44%), Gaps = 51/249 (20%)
Query: 509 ESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPF 567
+ ID K EI++++ L ++ +V++ + + + L+ME CG +L F
Sbjct: 141 KQDIDDVKREIQIMQYLSGQENIVEIKGAYEDRQSIHLVMELCGGSEL-----------F 189
Query: 568 DTEFVRYHFQE---------MIKCVKVVHDADIVHSDLKPANFVFVK----GMLKIIDFG 614
D + H+ E ++ V++ H ++H DLKP NF+ MLK DFG
Sbjct: 190 DRIIAQGHYSEKAAAGVIRSVLNVVQICHFMGVIHRDLKPENFLLASTDENAMLKATDFG 249
Query: 615 IANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILY 674
++ + + V YRD +G+ Y+APE L + GK D+WS G ILY
Sbjct: 250 LSVFIEEGKV--YRDI-VGSAYYVAPEVL-------------RRSYGKEIDIWSAGIILY 293
Query: 675 QMVYGKPPYGTFQGNNRLYAIMNPDVKI---PYPEKDSFGTVIPRTVIDTIRSCLERNPI 731
++ G PP+ + I+ ++ P+P I + D +R L ++P
Sbjct: 294 ILLCGVPPFWSETEKGIFNEIIKGEIDFDSQPWPS-------ISESAKDLVRKLLTKDPK 346
Query: 732 SRVTIDQLL 740
R++ Q L
Sbjct: 347 QRISAAQAL 355
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 80.1 bits (196), Expect = 1e-14
Identities = 80/297 (26%), Positives = 130/297 (42%), Gaps = 47/297 (15%)
Query: 472 YEKVELLXXXXXXXXXXXXXXD-HKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQR 530
YEK+E + + H++ ALKRV D+ DE EI LLK+L++K
Sbjct: 4 YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHK-N 62
Query: 531 VVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDAD 590
+V+L D L L+ E + DL + + D E V+ +++K + H +
Sbjct: 63 IVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNG-DLDPEIVKSFLFQLLKGLGFCHSRN 121
Query: 591 IVHSDLKPANFVFVK-GMLKIIDFGIANA--VPDHTVNIYRDNQIGTPNYMAPETLVAMN 647
++H DLKP N + + G LK+ DFG+A A +P V Y ++ T Y P+ L
Sbjct: 122 VLHRDLKPQNLLINRNGELKLADFGLARAFGIP---VRCY-SAEVVTLWYRPPDVLFGAK 177
Query: 648 FTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNN------RLYAIMN---- 697
D+WS GCI ++ P F GN+ R++ ++
Sbjct: 178 L-----------YSTSIDMWSAGCIFAELANAGRP--LFPGNDVDDQLKRIFRLLGTPTE 224
Query: 698 ---------PDVK--IPYPEKDSFGTVIPR---TVIDTIRSCLERNPISRVTIDQLL 740
PD K YP S V+P+ T D +++ L+ NP+ R++ ++ L
Sbjct: 225 EQWPSMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEAL 281
>CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1370
Score = 80.1 bits (196), Expect = 1e-14
Identities = 71/255 (27%), Positives = 116/255 (44%), Gaps = 37/255 (14%)
Query: 497 YALKRVSFDEFD-ESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-D 554
+ALK+++ + +D E ++L +N VV + L +LME E D
Sbjct: 384 FALKKMNKQTLMLRNQVDQVFAERDILTMADNPF-VVSFYGSFETRQYLCMLMEYVEGGD 442
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLKIIDF 613
+ +L +P E VR + E I ++ +H IVH DLKP N + G +K+ DF
Sbjct: 443 CAALLKSAGTLP--VELVRLYVAETILAIEYLHSYGIVHRDLKPDNLLITAMGHIKLTDF 500
Query: 614 GIAN-AVPDHTVNI------------YRDNQI-GTPNYMAPETLVAMNFTRNDGEQAKWK 659
G++ + + T + ++D Q+ GTP Y+APE ++ +
Sbjct: 501 GLSKIGLMNRTTLVAEGYDAVVETQQFQDKQLCGTPEYIAPEVILRRGY----------- 549
Query: 660 VGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVI 719
GKP D W+ G ILY+ + G P+ +++ DV+ YPE+D +P
Sbjct: 550 -GKPVDWWALGIILYEFLVGIVPFFGETPEALFSKVISEDVE--YPEEDE---ALPPEAA 603
Query: 720 DTIRSCLERNPISRV 734
D R LE+NP R+
Sbjct: 604 DLCRRLLEKNPAERL 618
>CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 615
Score = 80.1 bits (196), Expect = 1e-14
Identities = 64/223 (28%), Positives = 109/223 (48%), Gaps = 23/223 (10%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQ 577
E+E+ ++L ++ V + Q V F L C ++ L ++ QR P R++
Sbjct: 83 EVEIHRQLSHRNIVQFHHFFEDSQNVYFTLELCSKNSLMELNKQRG--PLTEHEARFYTI 140
Query: 578 EMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVNIYRDNQIGTPN 636
++ + VK +H+ I+H DLK N + + +KI DFG+A + + R GTPN
Sbjct: 141 QVAEGVKHLHNLQIIHRDLKLGNLFLNEHLQVKIGDFGLATFCEKNEKKMTRG---GTPN 197
Query: 637 YMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIM 696
Y+APE L N T + E D+W+ GCILY +++G PP+ + + I
Sbjct: 198 YIAPEVL---NETGHAFEV---------DIWAIGCILYVLLFGSPPFESRRVQETYVRIK 245
Query: 697 NPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISR-VTIDQ 738
N D +P + +I R+++D + +R P + V +DQ
Sbjct: 246 NNDYVVPENASPTANRLI-RSLLDPVP---DRRPTAEAVLLDQ 284
>At3g04810 [R] KOG0589 Serine/threonine protein kinase
Length = 606
Score = 80.1 bits (196), Expect = 1e-14
Identities = 63/258 (24%), Positives = 118/258 (45%), Gaps = 26/258 (10%)
Query: 493 DHKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQG--VLFLLMEC 550
+ K+Y LK++ + E+EL+ K+ N +V+ D + +G V ++ C
Sbjct: 26 EKKLYVLKKIRLARQTGRTRRSAHQEMELISKIHNPF-IVEYKDSWVEKGCYVCIIIGYC 84
Query: 551 GEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LK 609
D+++ + + + + F E + +++ ++ +H I+H D+K +N K ++
Sbjct: 85 KGGDMAEAIKKTNGVHFTEEKLCKWLVQILLALEYLHANHILHRDVKCSNIFLTKDQDIR 144
Query: 610 IIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
+ DFG+A + T + + +GTP+YM PE L + + G SD+WS
Sbjct: 145 LGDFGLAKVL---TSDDLASSVVGTPSYMCPELLADIPY------------GSKSDIWSL 189
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
GC +Y+M KP + F + I N + P P + S ++S L +N
Sbjct: 190 GCCMYEMTAMKPAFKAFDMQGLINRI-NRSIVPPLPAQYS------AAFRGLVKSMLRKN 242
Query: 730 PISRVTIDQLLSGALINP 747
P R + +LL L+ P
Sbjct: 243 PELRPSAAELLRQPLLQP 260
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 79.7 bits (195), Expect = 2e-14
Identities = 68/270 (25%), Positives = 115/270 (42%), Gaps = 55/270 (20%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGV----LFLLMECGEHDLSQVLTQRSKIPFDTEFVR 573
E++ + + + +V LID + L+ E ++DL++V+ S + ++
Sbjct: 87 ELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVI--HSSVQLSEFHIK 144
Query: 574 YHFQEMIKCVKVVHDADIVHSDLKPANFV-FVKGMLKIIDFGIANAVP------DHTVNI 626
Y +++ +K +H AD++H DLKP N + + G LKI DFG+A + TV
Sbjct: 145 YFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQP 204
Query: 627 YRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTF 686
+ N + T Y APE L+ + K D+W+ GCIL + KP F
Sbjct: 205 HITNYVATRWYRAPELLL-----------SNQPYSKSVDIWAVGCILAEFYARKP---VF 250
Query: 687 QGNNRLYAIMNPDVKIPYPEKD---SFGTV----------------IP---------RTV 718
G + ++ I + P+KD FGT+ IP
Sbjct: 251 MGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEA 310
Query: 719 IDTIRSCLERNPISRVTIDQLLSGALINPV 748
I+ I S L + R+ ++Q +S +N V
Sbjct: 311 INLIESLLHWDSTHRLNVEQAISHPFLNEV 340
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 79.7 bits (195), Expect = 2e-14
Identities = 63/251 (25%), Positives = 110/251 (43%), Gaps = 27/251 (10%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLS 556
A+K + + + SS+ E+ ++K L N +VKL + + L+L+ME ++
Sbjct: 86 AIKIIDKTQLNPSSLQKLFREVRIMKGL-NHPNIVKLFEVIETEKTLYLVMEYASAGEVF 144
Query: 557 QVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGI 615
L ++ + R F++++ V H +IVH DLK N + + +KI DFG
Sbjct: 145 DYLVSHGRMK--EKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGF 202
Query: 616 ANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQ 675
+N + T+ D G+P Y APE Q K G D+WS G ILY
Sbjct: 203 SN---EFTLGSKLDTFCGSPPYAAPELF-----------QGKKYDGPEVDIWSLGVILYT 248
Query: 676 MVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVT 735
+V G P+ ++ ++P+ +++ R ++ NP R T
Sbjct: 249 LVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLV--------LNPAKRCT 300
Query: 736 IDQLLSGALIN 746
++Q++ IN
Sbjct: 301 LEQIMKDKWIN 311
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 79.3 bits (194), Expect = 2e-14
Identities = 52/166 (31%), Positives = 87/166 (52%), Gaps = 22/166 (13%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGV-LFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHF 576
E++LLK L + + ++ L D + ++ + E DL ++LT R P +T+F++Y
Sbjct: 67 ELKLLKHLRH-ENIISLSDIFISPFEDIYFVTELLGTDLHRLLTSR---PLETQFIQYFL 122
Query: 577 QEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVNIYRDNQIGTP 635
++++ +K VH A ++H DLKP+N + + LKI DFG+A + D + Y + T
Sbjct: 123 YQILRGLKFVHSAGVIHRDLKPSNILINENCDLKICDFGLAR-IQDPQMTGY----VSTR 177
Query: 636 NYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKP 681
Y APE ++ K D+WS GCI +M+ GKP
Sbjct: 178 YYRAPEIMLTWQ-----------KYNVEVDIWSAGCIFAEMIEGKP 212
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 79.3 bits (194), Expect = 2e-14
Identities = 53/190 (27%), Positives = 94/190 (48%), Gaps = 18/190 (9%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHD 554
+V ALK + E + + EIE+++ L + +V ++D + ++ + E +
Sbjct: 28 QVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPN-IVHMLDSFETDKEVVVVTDYAEGE 86
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDF 613
L Q+L K+P D V+ +++ + +H I+H D+KP N + KG +K+ DF
Sbjct: 87 LFQILEDDGKLPEDQ--VQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDF 144
Query: 614 GIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCIL 673
G A A+ +T+ + GTP YM+PE + + +D+WS GCIL
Sbjct: 145 GFARAMSTNTMVLTSIK--GTPLYMSPELVEERPYDHT------------ADLWSVGCIL 190
Query: 674 YQMVYGKPPY 683
Y++ G PP+
Sbjct: 191 YELAVGTPPF 200
>At5g66850 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 376
Score = 79.3 bits (194), Expect = 2e-14
Identities = 51/173 (29%), Positives = 82/173 (46%), Gaps = 22/173 (12%)
Query: 572 VRYHFQEMIKCVKVVHDADIVHSDLKPANF-VFVKGMLKIIDFGIANAVPDHTVNIYRDN 630
VR + ++ + +H+ VH D+K AN V G++K+ DFG+A + ++ +
Sbjct: 108 VRNFTRHILSGLAYLHNKKTVHRDIKGANLLVDASGVVKLADFGMAKHLTGQRADL---S 164
Query: 631 QIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNN 690
G+P +MAPE L+ ++ + V D+WS GC + +M GKPP+ F+G
Sbjct: 165 LKGSPYWMAPEVLMQAVMQKDSNPDLAFAV----DIWSLGCTIIEMFTGKPPWSEFEGAA 220
Query: 691 RLYAIMNPDVKIP---YPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
++ +M IP PE F +R C +RNP R T LL
Sbjct: 221 AMFKVMRDSPPIPESMSPEGKDF-----------LRLCFQRNPAERPTASMLL 262
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 79.3 bits (194), Expect = 2e-14
Identities = 59/190 (31%), Positives = 95/190 (49%), Gaps = 17/190 (8%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKL--IDYHMGQGVLFLLMECGE 552
K+ ALK+V FD SI EI +L+KL N ++KL I ++L+ E E
Sbjct: 129 KMVALKKVKFDNLQPESIRFMAREILILRKL-NHPNIMKLEGIVTSRASSSIYLVFEYME 187
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLKII 611
HDL+ L+ I F ++ + ++++ ++ H ++H D+K +N V KG+LK+
Sbjct: 188 HDLAG-LSSNPDIRFTEPQIKCYMKQLLWGLEHCHMRGVIHRDIKASNILVNNKGVLKLG 246
Query: 612 DFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGC 671
DFG+AN V N +++ T Y APE L+ G D+WS GC
Sbjct: 247 DFGLANVVTPSNKN-QLTSRVVTLWYRAPELLMGST-----------SYGVSVDLWSVGC 294
Query: 672 ILYQMVYGKP 681
+ +++ GKP
Sbjct: 295 VFAEILMGKP 304
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 79.0 bits (193), Expect = 3e-14
Identities = 73/277 (26%), Positives = 126/277 (45%), Gaps = 52/277 (18%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQ 557
ALK V D + + + EI L+K+L++ + +V+L D + L L+ E ++DL +
Sbjct: 34 ALKEVKLDSEEGTPSTAIR-EISLMKELKH-ENIVRLYDVIHTENKLTLVFEFMDNDLKK 91
Query: 558 VLTQRS--KIP--FDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIID 612
+ R+ P + V+Y ++++ + H+ I+H DLKP N + K G LK+ D
Sbjct: 92 YMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGD 151
Query: 613 FGIANA--VPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
FG+A A +P +T + +++ T Y AP+ L+ D+WSCG
Sbjct: 152 FGLARAFGIPVNTFS----SEVVTLWYRAPDVLMGSR-----------TYSTSIDIWSCG 196
Query: 671 CILYQMVYGKPPYGTFQGNNRLYAIM--------------------NPDVKIPYPEKDSF 710
CIL +M+ GKP + +L I NP+++ P +D
Sbjct: 197 CILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQ-QRPPRDLR 255
Query: 711 GTVIPRT-------VIDTIRSCLERNPISRVTIDQLL 740
+ P T ++D + L+ NP R++ Q L
Sbjct: 256 QVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQAL 292
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 79.0 bits (193), Expect = 3e-14
Identities = 64/229 (27%), Positives = 109/229 (46%), Gaps = 23/229 (10%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFL---LMECGEHDLSQVLTQRSKIPFDTEFVRY 574
E+++L+K+ +++L D + FL LM+ GE L LT+ K+ + R
Sbjct: 74 EVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGE--LFDYLTE--KVTLSEKETRK 129
Query: 575 HFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAV-PDHTVNIYRDNQI 632
+ +++ + +H +IVH DLKP N + M +K+ DFG + + P +
Sbjct: 130 IMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLR----EVC 185
Query: 633 GTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRL 692
GTP+Y+APE + + G GK D+WS G I+Y ++ G PP+ + L
Sbjct: 186 GTPSYLAPEIIECSMNEDHPG------YGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLML 239
Query: 693 YAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLS 741
IM+ + + PE D + TV D + L P +R T ++ L+
Sbjct: 240 RMIMSGNYQFGSPEWDDYSD----TVKDLVSRFLVVQPQNRYTAEEALA 284
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 78.6 bits (192), Expect = 4e-14
Identities = 63/229 (27%), Positives = 102/229 (44%), Gaps = 38/229 (16%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQ 577
EI LK L + ++KL D + +++E +L + ++ ++ D R FQ
Sbjct: 82 EISYLKLLRHPH-IIKLYDVITTPTDIVMVIEYAGGELFDYIVEKKRMTEDEG--RRFFQ 138
Query: 578 EMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVNIYRDNQIGTPN 636
++I ++ H IVH DLKP N + + +KI DFG++N + D + G+PN
Sbjct: 139 QIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNIMTDGN---FLKTSCGSPN 195
Query: 637 YMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPY------GTFQGNN 690
Y APE + K G DVWSCG +LY M+ G+ P+ F+ N
Sbjct: 196 YAAPEVI-----------NGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVN 244
Query: 691 RLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQL 739
+M PD P + IR + +P+ R+TI ++
Sbjct: 245 SCVYVM-PDFLSPGAQ-------------SLIRRMIVADPMQRITIQEI 279
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 78.6 bits (192), Expect = 4e-14
Identities = 68/251 (27%), Positives = 109/251 (43%), Gaps = 27/251 (10%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHD-LS 556
A+K + + + +S+ E+ ++K L N +VKL + Q L+L+ME +
Sbjct: 83 AIKIIDKTQLNPTSLQKLFREVRIMKIL-NHPNIVKLFEVIETQKTLYLIMEYASGGKVF 141
Query: 557 QVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGI 615
L ++ + R F++++ V+ H IVH DLK N + M +KI DFG
Sbjct: 142 DYLVAHGRMK--EKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGF 199
Query: 616 ANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQ 675
+N + TV D G+P Y APE Q K G DVWS G ILY
Sbjct: 200 SN---EFTVGGKLDTFCGSPPYAAPELF-----------QGKKYDGPEVDVWSLGVILYT 245
Query: 676 MVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVT 735
+V G P+ ++ +IP+ ++ R ++ NPI R T
Sbjct: 246 LVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLV--------LNPIKRGT 297
Query: 736 IDQLLSGALIN 746
++Q++ IN
Sbjct: 298 LEQIMKDRWIN 308
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 78.6 bits (192), Expect = 4e-14
Identities = 77/302 (25%), Positives = 140/302 (45%), Gaps = 31/302 (10%)
Query: 494 HKVYALKRVSFDEFDESSID-GFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGE 552
HKV A+K ++ + I+ + EI++L+ L + +++ + ++++ME +
Sbjct: 43 HKV-AIKILNRSKIKNMGIEIKVQREIKILRFLMHPH-IIRQYEVIETPNDIYVVMEYVK 100
Query: 553 H-DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKI 610
+L + ++ K+ D R+ FQ++I V+ H IVH DLKP N + +KI
Sbjct: 101 SGELFDYIVEKGKLQEDE--ARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKI 158
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
+DFG++N + D + G+PNY APE + + G D+WSCG
Sbjct: 159 VDFGLSNVMHD---GHFLKTSCGSPNYAAPEVISGKPY------------GPDVDIWSCG 203
Query: 671 CILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVI--DTIR---SC 725
ILY ++ G P+ N I +P +IPR ++ T+R +
Sbjct: 204 VILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITE 263
Query: 726 LERNPISRVTIDQLLSGALINPVTVTKFFIHDLIKNAVNYGCDQKHVNNERVEELSEDVW 785
+ ++P + LS ++ + K ++I+N VN G D+ HV V+ L+ +
Sbjct: 264 IRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHV----VDSLANRIQ 319
Query: 786 NK 787
N+
Sbjct: 320 NE 321
>At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 78.6 bits (192), Expect = 4e-14
Identities = 73/268 (27%), Positives = 116/268 (43%), Gaps = 54/268 (20%)
Query: 497 YALKRVSFDEFDES-SIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHD 554
YA K +S + + I+ + E+E++K + +V L D + ++ME C +
Sbjct: 83 YACKSISKKKLRTAVDIEDVRREVEIMKHMPRHPNIVSLKDAFEDDDAVHIVMELCEGGE 142
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQE---------MIKCVKVVHDADIVHSDLKPANFVFVK 605
L FD R H+ E +++ V++ H ++H DLKP NF+F
Sbjct: 143 L-----------FDRIVARGHYTERAAAAVMKTILEVVQICHKHGVMHRDLKPENFLFAN 191
Query: 606 ----GMLKIIDFGIANAV-PDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKV 660
LK IDFG++ P N +G+P YMAPE L RN G +
Sbjct: 192 KKETSALKAIDFGLSVFFKPGEGFN----EIVGSPYYMAPEVL-----RRNYGPEV---- 238
Query: 661 GKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDV---KIPYPEKDSFGTVIPRT 717
D+WS G ILY ++ G PP+ AI+ + + P+P + T
Sbjct: 239 ----DIWSAGVILYILLCGVPPFWAETEQGVAQAIIRSVIDFKRDPWPR-------VSET 287
Query: 718 VIDTIRSCLERNPISRVTIDQLLSGALI 745
D +R LE +P R++ Q+L + I
Sbjct: 288 AKDLVRKMLEPDPKKRLSAAQVLEHSWI 315
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 78.6 bits (192), Expect = 4e-14
Identities = 63/245 (25%), Positives = 109/245 (43%), Gaps = 24/245 (9%)
Query: 498 ALKRVSFDEFDESSIDG-FKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLS 556
A+K VS + ++G + EI ++ +L + +V+L + + +F +ME +
Sbjct: 49 AIKVVSKQRLQKGGLNGNIQREIAIMHRLRHPS-IVRLFEVLATKSKIFFVMEFAKG--G 105
Query: 557 QVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGI 615
++ + SK F + R +FQ++I V H I H DLKP N + + + LKI DFG+
Sbjct: 106 ELFAKVSKGRFCEDLSRRYFQQLISAVGYCHSRGIFHRDLKPENLLLDEKLDLKISDFGL 165
Query: 616 ANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQ 675
+ + GTP Y+APE L + G D+WSCG IL+
Sbjct: 166 SALTDQIRPDGLLHTLCGTPAYVAPEVLAKKGYD-----------GAKIDIWSCGIILFV 214
Query: 676 MVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVT 735
+ G P+ I + +IP ++ R L+ NP +R+T
Sbjct: 215 LNAGYLPFNDHNLMVMYRKIYKGEFRIPKWTSPDLRRLLTR--------LLDTNPQTRIT 266
Query: 736 IDQLL 740
I++++
Sbjct: 267 IEEII 271
>At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 78.6 bits (192), Expect = 4e-14
Identities = 69/259 (26%), Positives = 113/259 (42%), Gaps = 54/259 (20%)
Query: 499 LKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQ 557
LKR E + K EI++++ L + VV++ + + + L+ME C +L
Sbjct: 101 LKRKLISELGREDV---KTEIQIMQHLSGQPNVVEIKGSYEDRHSVHLVMELCAGGEL-- 155
Query: 558 VLTQRSKIPFDTEFVRYHFQE---------MIKCVKVVHDADIVHSDLKPANFVFVK--- 605
FD + H+ E ++ V++ H ++H DLKP NF+F
Sbjct: 156 ---------FDRIIAQGHYSERAAAGTIKSIVDVVQICHLNGVIHRDLKPENFLFSSKEE 206
Query: 606 -GMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPS 664
MLK+ DFG++ + + IY+D +G+P Y+APE L + GK
Sbjct: 207 NAMLKVTDFGLSAFIEEG--KIYKD-VVGSPYYVAPEVL-------------RQSYGKEI 250
Query: 665 DVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMN---PDVKIPYPEKDSFGTVIPRTVIDT 721
D+WS G ILY ++ G PP+ I+ V+ P+P I + D
Sbjct: 251 DIWSAGVILYILLCGVPPFWADNEEGVFVEILKCKIDFVREPWPS-------ISDSAKDL 303
Query: 722 IRSCLERNPISRVTIDQLL 740
+ L +P R+T Q+L
Sbjct: 304 VEKMLTEDPKRRITAAQVL 322
>At2g32510 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 372
Score = 78.6 bits (192), Expect = 4e-14
Identities = 65/221 (29%), Positives = 99/221 (44%), Gaps = 26/221 (11%)
Query: 568 DTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFV-KGMLKIIDFGIANAVPDHTVNI 626
+T V+Y ++++K ++ +H IVH D+K +N V KG KI DFG A V +
Sbjct: 100 ETRVVKYT-RDILKGLEYIHSKGIVHCDVKGSNVVISEKGEAKIADFGCAKRVDP----V 154
Query: 627 YRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTF 686
+ +GTP +MAPE GE K GK SD+W+ GC + +MV G PP+
Sbjct: 155 FESPVMGTPAFMAPEVA--------RGE----KQGKESDIWAVGCTMIEMVTGSPPWTKA 202
Query: 687 QGNNRLYAIMNPDVKIPY-PEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGA-L 744
+++ ++ Y E ++ D + CL+R R T QLL+ L
Sbjct: 203 DSREDPVSVL---YRVGYSSETPELPCLLAEEAKDFLEKCLKREANERWTATQLLNHPFL 259
Query: 745 INPVTVTKFFIHDLIKNAVNYGCDQ---KHVNNERVEELSE 782
+ + LI N+ DQ + V E EE E
Sbjct: 260 TTKPDIEPVLVPGLISNSPTSVTDQTFWRSVEEEEEEETEE 300
>7302458 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 596
Score = 78.6 bits (192), Expect = 4e-14
Identities = 65/240 (27%), Positives = 107/240 (44%), Gaps = 25/240 (10%)
Query: 509 ESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPF 567
ES + EI ++++ ++ VV+ + Q L++ ME CG +S ++ R K
Sbjct: 76 ESDLHEIIKEISIMQQCDSPY-VVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLT 134
Query: 568 DTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNI 626
+ E + ++ + +H +H D+K AN + +G K+ DFG+A + D
Sbjct: 135 EDEIATI-LSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAK- 192
Query: 627 YRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTF 686
R+ IGTP +MAPE + + + +D+WS G +M GKPPYG
Sbjct: 193 -RNTVIGTPFWMAPEVIEEIGYDC------------VADIWSLGITALEMAEGKPPYGEI 239
Query: 687 QGNNRLYAIMNPDVKIP-YPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALI 745
++ I P P + E D + T ID + CL + P R T +LL I
Sbjct: 240 HPMRAIFMI--PQKPPPSFREPDRWST----EFIDFVSKCLVKEPDDRATATELLEHEFI 293
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 78.2 bits (191), Expect = 5e-14
Identities = 71/249 (28%), Positives = 110/249 (43%), Gaps = 28/249 (11%)
Query: 494 HKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQ-RVVKLIDYHMGQGVLFLLMEC-- 550
+K+YA K ++ + E D K EI +LK++ + ++ L+D+ L+L+ E
Sbjct: 54 NKMYAAKIMN-KKMMEKKQDFVKNEIAILKRVSYEHPNILHLVDFFETVNNLYLITELAT 112
Query: 551 GEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF----VKG 606
G ++ + S D + + VK +HD IVH DLKP N ++
Sbjct: 113 GGELFDRICAKGSFYEADAAAL---MRTTTSAVKYLHDNGIVHRDLKPENLLYRSKDPNS 169
Query: 607 MLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDV 666
L I DFG+++ D + GTP YMAPE R G GKP D+
Sbjct: 170 DLLIADFGLSHFYEDSQYYMLM-TACGTPEYMAPEVF------RRTG------YGKPVDM 216
Query: 667 WSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCL 726
W+ G I Y ++ G P+ + AI+ + Y D + I T D I+ CL
Sbjct: 217 WAIGVITYFLLSGYTPFARPSQVEVIEAILANE----YTFNDPCWSGISETAKDFIKKCL 272
Query: 727 ERNPISRVT 735
E +P R+T
Sbjct: 273 ENDPSKRLT 281
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 78.2 bits (191), Expect = 5e-14
Identities = 61/248 (24%), Positives = 110/248 (43%), Gaps = 28/248 (11%)
Query: 494 HKVYALKRVSFDEFDESSIDG-FKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGE 552
H + ALK + + ++ ++ + EIE+ L + +++L +Y + ++L++E
Sbjct: 100 HFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPN-ILRLYNYFYDRRRIYLILEYAP 158
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKII 611
Q+S FD + +E+ + H ++H D+KP N + +KG LKI
Sbjct: 159 RGELYKELQKS-CTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIA 217
Query: 612 DFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGC 671
DFG + H ++ R GT +Y+ PE + +G KV D+W G
Sbjct: 218 DFGWSV----HAPSLRRKTMCGTLDYLPPEMI--------EGRMHNEKV----DLWCIGV 261
Query: 672 ILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPI 731
+ Y+++ G PP+ + N I+ D+K P +P D I L NP
Sbjct: 262 LCYELLVGNPPFESASHNETYRRIVKVDLKFP--------ASVPTGAQDLISKLLRHNPS 313
Query: 732 SRVTIDQL 739
R+ + Q+
Sbjct: 314 ERLPLAQV 321
>At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 599
Score = 78.2 bits (191), Expect = 5e-14
Identities = 63/237 (26%), Positives = 110/237 (45%), Gaps = 30/237 (12%)
Query: 511 SIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDL-SQVLTQRSKIPFD 568
SI+ + E+++L+ L Q +V+ D ++++ME CG +L ++L + K +
Sbjct: 188 SIEDVRREVKILRALSGHQNLVQFYDAFEDNANVYIVMELCGGGELLDRILARGGK--YS 245
Query: 569 TEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFV----KGMLKIIDFGIANAV-PDHT 623
+ + +++ V H +VH DLKP NF++ MLK+IDFG+++ V PD
Sbjct: 246 EDDAKAVLIQILNVVAFCHLQGVVHRDLKPENFLYTSKEENSMLKVIDFGLSDFVRPDER 305
Query: 624 VNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPY 683
+N + +G+ Y+APE L T +DVWS G I Y ++ G P+
Sbjct: 306 LN----DIVGSAYYVAPEVLHRSYTTE-------------ADVWSIGVIAYILLCGSRPF 348
Query: 684 GTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
+ A++ D P S + D ++ L ++P R+T Q L
Sbjct: 349 WARTESGIFRAVLKADPSFDEPPWPS----LSFEAKDFVKRLLYKDPRKRMTASQAL 401
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 78.2 bits (191), Expect = 5e-14
Identities = 58/190 (30%), Positives = 97/190 (50%), Gaps = 17/190 (8%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLE--NKQRVVKLIDYHMGQGVLFLLMECGE 552
K+ A+K+V F D S+ EI +L+KL+ N ++ L+ + G L+L+ E E
Sbjct: 171 KIVAMKKVRFVNMDPESVRFMAREILILRKLDHPNVMKLEGLVTSRLS-GSLYLVFEYME 229
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFV-KGMLKII 611
HDL+ L I F ++ + Q++ + ++ H I+H D+K +N + +G+LKI
Sbjct: 230 HDLAG-LAATPGIKFSEPQIKCYMQQLFRGLEHCHRRGILHRDIKGSNLLINNEGVLKIG 288
Query: 612 DFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGC 671
DFG+AN ++ +++ T Y APE L+ + G D+WS GC
Sbjct: 289 DFGLANFYRGDG-DLQLTSRVVTLWYRAPELLLGAT-----------EYGPAIDLWSAGC 336
Query: 672 ILYQMVYGKP 681
IL ++ GKP
Sbjct: 337 ILTELFAGKP 346
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 77.8 bits (190), Expect = 6e-14
Identities = 67/252 (26%), Positives = 116/252 (45%), Gaps = 30/252 (11%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLE-----NKQRVVKLIDYHMGQGVLFLLME 549
+++A K V+ ++SI K +LL +++ + +V+ ID +++L+E
Sbjct: 105 EIFAAKTVA-----KASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLE 159
Query: 550 CGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-L 608
+ L +R K+ + E VR+ ++ +K +H ++H DLK N F L
Sbjct: 160 ICPNGSLMELLKRRKVLTEPE-VRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNL 218
Query: 609 KIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWS 668
KI DFG+A + + + Y GTPNY+APE L+ ++ G + D+WS
Sbjct: 219 KIGDFGLAAVLANESERKY--TICGTPNYIAPEVLMG----KHSGHSFE------VDIWS 266
Query: 669 CGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLER 728
G +LY ++ GKPP+ N I D P + S I IR L
Sbjct: 267 LGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKI------LIRDILSL 320
Query: 729 NPISRVTIDQLL 740
+PI R ++ +++
Sbjct: 321 DPIERPSLTEIM 332
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 77.8 bits (190), Expect = 6e-14
Identities = 61/227 (26%), Positives = 111/227 (48%), Gaps = 31/227 (13%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGV----LFLLMECGEHDLSQVLTQRSKIPFDTEFVR 573
E+ +L++L + + ++ ++D +G ++L+M+ E DL Q+L R + + +
Sbjct: 104 EVRILRELLH-ENIIAVLDMFTAEGAHGKDIYLVMDLMETDLHQILHSRQTLM--EQHFQ 160
Query: 574 YHFQEMIKCVKVVHDADIVHSDLKPANFVFVKG--MLKIIDFGIANAV-------PDHTV 624
Y F ++++ +K +H A I+H DLKP+N + + G +L+I DFG+A A D V
Sbjct: 161 YFFYQLLRGLKYLHSAGIIHRDLKPSN-LLLNGDCLLRIADFGMARAYASASTVRDDANV 219
Query: 625 NIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYG 684
+ + T Y APE L +M + KV D+WS GCI +M+ +
Sbjct: 220 GGHMTQYVSTRWYRAPEILFSM-------VEYDTKV----DLWSAGCIFAEMLLRRQ--- 265
Query: 685 TFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPI 731
F G + + I + PE++ + V D+I +C + P+
Sbjct: 266 LFPGKDSVSQIKMIVYYLGSPEEEVINRITSDLVRDSIEACGRKTPL 312
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 77.8 bits (190), Expect = 6e-14
Identities = 65/230 (28%), Positives = 113/230 (48%), Gaps = 26/230 (11%)
Query: 512 IDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTE 570
+D K EI ++K L VV+L + + +++++E +L + + ++ ++E
Sbjct: 51 VDQIKREISIMK-LVRHPCVVRLYEVLASRTKIYIILEYITGGELFDKIVRNGRLS-ESE 108
Query: 571 FVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYRD 629
R +F ++I V H + H DLKP N + +G LKI DFG++ A+P+ V I +
Sbjct: 109 -ARKYFHQLIDGVDYCHSKGVYHRDLKPENLLLDSQGNLKISDFGLS-ALPEQGVTILKT 166
Query: 630 NQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGN 689
GTPNY+APE L + G +D+WSCG ILY ++ G P+
Sbjct: 167 T-CGTPNYVAPEVLSHKGYN-----------GAVADIWSCGVILYVLMAGYLPFDEMDLP 214
Query: 690 NRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQL 739
I + P S+ + +++I+ I L+ NP +R+TI ++
Sbjct: 215 TLYSKIDKAEFSCP-----SYFALGAKSLINRI---LDPNPETRITIAEI 256
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 77.8 bits (190), Expect = 6e-14
Identities = 59/191 (30%), Positives = 97/191 (49%), Gaps = 19/191 (9%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLE--NKQRVVKLIDYHMGQGVLFLLMECGE 552
K+ A+K+V F D S+ EI +L+KL+ N ++ L+ + G L+L+ E E
Sbjct: 180 KMVAMKKVRFVNMDPESVRFMAREINILRKLDHPNVMKLECLVTSKLS-GSLYLVFEYME 238
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKII 611
HDLS L R + F ++ + ++++ ++ H I+H D+K N + G+LKI
Sbjct: 239 HDLSG-LALRPGVKFTESQIKCYMKQLLSGLEHCHSRGILHRDIKGPNLLVNNDGVLKIG 297
Query: 612 DFGIANAV-PDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG+AN P+ + +++ T Y APE L+ + G D+WS G
Sbjct: 298 DFGLANIYHPEQDQPL--TSRVVTLWYRAPELLLGAT-----------EYGPGIDLWSVG 344
Query: 671 CILYQMVYGKP 681
CIL ++ GKP
Sbjct: 345 CILTELFLGKP 355
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 77.8 bits (190), Expect = 6e-14
Identities = 67/262 (25%), Positives = 118/262 (44%), Gaps = 24/262 (9%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTEFVRYHF 576
EI++L+ L +++L + ++L+ME +L + ++ ++ D R F
Sbjct: 67 EIKILR-LFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDE--ARNFF 123
Query: 577 QEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYRDNQIGTP 635
Q++I V+ H +VH DLKP N + K +KI DFG++N + D + G+P
Sbjct: 124 QQIISGVEYCHRNMVVHRDLKPENLLLDSKCNVKIADFGLSNIMRD---GHFLKTSCGSP 180
Query: 636 NYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAI 695
NY APE + K G DVWSCG ILY ++ G P+ N I
Sbjct: 181 NYAAPEVI-----------SGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKI 229
Query: 696 MNPDVKIPYPEKDSFGTVIPR-TVIDTIRSC----LERNPISRVTIDQLLSGALINPVTV 750
+P +IPR V+D ++ + ++P + + + L+ + V
Sbjct: 230 KGGIYTLPSHLSPGARDLIPRMLVVDPMKRVTIPEIRQHPWFQAHLPRYLAVPPPDTVQQ 289
Query: 751 TKFFIHDLIKNAVNYGCDQKHV 772
K ++++ +N G D+ H+
Sbjct: 290 AKKIDEEILQEVINMGFDRNHL 311
>At1g54510 [R] KOG0589 Serine/threonine protein kinase
Length = 612
Score = 77.8 bits (190), Expect = 6e-14
Identities = 63/258 (24%), Positives = 116/258 (44%), Gaps = 26/258 (10%)
Query: 493 DHKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQG--VLFLLMEC 550
+ K Y LK++ + + E+EL+ K+ + +V+ D + + V ++ C
Sbjct: 26 EKKKYVLKKIRLARQTQRTRRSAHQEMELISKMRHPF-IVEYKDSWVEKACYVCIVIGYC 84
Query: 551 GEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LK 609
D++Q + + + + F E + +++ ++ +H I+H D+K +N K ++
Sbjct: 85 EGGDMAQAIKKSNGVHFQEEKLCKWLVQLLMGLEYLHSNHILHRDVKCSNIFLTKEQDIR 144
Query: 610 IIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
+ DFG+A + T + + +GTP+YM PE L + + G SD+WS
Sbjct: 145 LGDFGLAKIL---TSDDLTSSVVGTPSYMCPELLADIPY------------GSKSDIWSL 189
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
GC +Y+M Y KP + F L +N + P P K S ++S L +N
Sbjct: 190 GCCIYEMAYLKPAFKAFD-MQALINKINKTIVSPLPAKYS------GPFRGLVKSMLRKN 242
Query: 730 PISRVTIDQLLSGALINP 747
P R + LL + P
Sbjct: 243 PEVRPSASDLLRHPHLQP 260
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 77.8 bits (190), Expect = 6e-14
Identities = 73/228 (32%), Positives = 114/228 (49%), Gaps = 34/228 (14%)
Query: 516 KGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DLSQVLTQRSKIPFDTEFVRY 574
K EI LK L++ +V+L + + +++++EC DL + + K+ +T+ R
Sbjct: 57 KREIRTLKVLKHPN-IVRLHEVLASKTKIYMVLECVTGGDLFDRIVSKGKLS-ETQG-RK 113
Query: 575 HFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYRDNQI- 632
FQ++I V H+ + H DLK N + KG +KI DFG++ A+ H YR++ +
Sbjct: 114 MFQQLIDGVSYCHNKGVFHRDLKLENVLLDAKGHIKITDFGLS-ALSQH----YREDGLL 168
Query: 633 ----GTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQG 688
G+PNY+APE L N+G G SD+WSCG ILY ++ G P+
Sbjct: 169 HTTCGSPNYVAPEVLA------NEGYD-----GAASDIWSCGVILYVILTGCLPFDDANL 217
Query: 689 NNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTI 736
I D P P S G +T+ I+ L+ NP++RVTI
Sbjct: 218 AVICRKIFKGDP--PIPRWISLGA---KTM---IKRMLDPNPVTRVTI 257
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 77.4 bits (189), Expect = 8e-14
Identities = 56/233 (24%), Positives = 109/233 (46%), Gaps = 29/233 (12%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGV-----LFLLMECGEHDLSQVLTQRSKIPFDT--- 569
EI+LL+ + ++ ++D + ++L+ E E DL +V+ ++ F T
Sbjct: 59 EIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNS-GFSTLSD 117
Query: 570 EFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPD-----HT 623
+ V+Y ++++ +K +H A ++H D+KP+N + LK+ DFG+A + T
Sbjct: 118 DHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRET 177
Query: 624 VNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPY 683
+ + + T Y APE ++ + D+WSCGCIL +MV GKP +
Sbjct: 178 LVGFMTEYVATRWYRAPEIMLTFQ-----------EYTTAMDIWSCGCILAEMVSGKPLF 226
Query: 684 GTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTI 736
+++L+ I+ + P + F + + + I + R P+ T+
Sbjct: 227 PGRDYHHQLWLILE---VLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETV 276
>YBR274w [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 527
Score = 77.4 bits (189), Expect = 8e-14
Identities = 63/232 (27%), Positives = 120/232 (51%), Gaps = 31/232 (13%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DLSQVLTQRSKIPFDTEFVRYHF 576
E+ L K V++LID ++ + +++++E + DL + + D++ +++F
Sbjct: 65 EVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKI--EPDVGVDSDVAQFYF 122
Query: 577 QEMIKCVKVVH-DADIVHSDLKPANFVFVK-GMLKIIDFGIANAV--PDHTVNIYRDNQI 632
Q+++ + +H + + H D+KP N + K G LK+ DFG+A+ D T+ + D Q
Sbjct: 123 QQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMD-QR 181
Query: 633 GTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRL 692
G+P YMAPE L + +G A +D+WS G +L+ ++ G+ P+ L
Sbjct: 182 GSPPYMAPEVLYS-----EEGYYA-----DRTDIWSIGILLFVLLTGQTPW-------EL 224
Query: 693 YAIMNPDVKIPYPEKD---SFG--TVIPRTVIDTIRSCLERNPISRVTIDQL 739
++ N D + + E D ++G + I T ++ +R L+ +P RVT+ L
Sbjct: 225 PSLENEDF-VFFIENDGNLNWGPWSKIEFTHLNLLRKILQPDPNKRVTLKAL 275
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 77.4 bits (189), Expect = 8e-14
Identities = 73/255 (28%), Positives = 120/255 (46%), Gaps = 27/255 (10%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEH 553
KV KR D + ++ +G+I+ + + N + +L+D + +L+ME C
Sbjct: 91 KVIDKKRAKKDTYVTKNLRR-EGQIQQMIRHPN---ITQLLDILETENSYYLVMELCPGG 146
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIID 612
+L + ++ ++ ++E RY +++I V+ +H A +VH DLK N + + +K+ID
Sbjct: 147 NLMHKIYEKKRLE-ESEARRY-IRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLID 204
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG++N + Q G+P Y APE L A+ K G DVWS G
Sbjct: 205 FGLSNCAGILGYSDPFSTQCGSPAYAAPELL------------ARKKYGPKIDVWSIGVN 252
Query: 673 LYQMVYGKPPYGTFQGNNR-LYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPI 731
+Y M+ G P+ + R LY M P P + S G I +RS LE +P+
Sbjct: 253 MYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTG------AISFLRSLLEPDPV 306
Query: 732 SRVTIDQLLSGALIN 746
R I Q L+ +N
Sbjct: 307 KRPNIQQALANRWLN 321
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 77.4 bits (189), Expect = 8e-14
Identities = 54/190 (28%), Positives = 90/190 (46%), Gaps = 12/190 (6%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHD 554
KVYA+K +S E + S F E + N VV+L L+++ME
Sbjct: 116 KVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPG- 174
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDF 613
++ S ++ +++ E++ + +H ++H D+KP N + K G LK+ DF
Sbjct: 175 -GDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADF 233
Query: 614 GIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCIL 673
G + D T ++ D +GTP+Y++PE L + DG G+ D WS G L
Sbjct: 234 GTCMKM-DETGMVHCDTAVGTPDYISPEVLKSQG---GDG-----FYGRECDWWSVGVFL 284
Query: 674 YQMVYGKPPY 683
Y+M+ G P+
Sbjct: 285 YEMLVGDTPF 294
>Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 77.4 bits (189), Expect = 8e-14
Identities = 54/190 (28%), Positives = 90/190 (46%), Gaps = 12/190 (6%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHD 554
KVYA+K +S E + S F E + N VV+L L+++ME
Sbjct: 116 KVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPG- 174
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDF 613
++ S ++ +++ E++ + +H ++H D+KP N + K G LK+ DF
Sbjct: 175 -GDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADF 233
Query: 614 GIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCIL 673
G + D T ++ D +GTP+Y++PE L + DG G+ D WS G L
Sbjct: 234 GTCMKM-DETGMVHCDTAVGTPDYISPEVLKSQG---GDG-----FYGRECDWWSVGVFL 284
Query: 674 YQMVYGKPPY 683
Y+M+ G P+
Sbjct: 285 YEMLVGDTPF 294
>CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 77.4 bits (189), Expect = 8e-14
Identities = 73/251 (29%), Positives = 111/251 (44%), Gaps = 31/251 (12%)
Query: 497 YALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DL 555
+A K ++ + + E + +KL++ +V+L D + +L+ + +L
Sbjct: 38 FAAKIINTKKLSARDFQKLEREARICRKLQHPN-IVRLHDSIQEESFHYLVFDLVTGGEL 96
Query: 556 SQVLTQRSKIPFDTEFVRYH-FQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKI 610
+ + R F +E H Q++++ + H IVH DLKP N + +K+
Sbjct: 97 FEDIVARE---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKL 153
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG+A V D GTP Y++PE L K KP D+W+CG
Sbjct: 154 ADFGLAIEVNDSEA---WHGFAGTPGYLSPEVL------------KKDPYSKPVDIWACG 198
Query: 671 CILYQMVYGKPPYGTFQGNNRLYA-IMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
ILY ++ G PP+ + +RLYA I P PE D TV P I S L N
Sbjct: 199 VILYILLVGYPPFWD-EDQHRLYAQIKAGAYDYPSPEWD---TVTPEAK-SLIDSMLTVN 253
Query: 730 PISRVTIDQLL 740
P R+T DQ L
Sbjct: 254 PKKRITADQAL 264
>CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 77.4 bits (189), Expect = 8e-14
Identities = 73/251 (29%), Positives = 111/251 (44%), Gaps = 31/251 (12%)
Query: 497 YALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DL 555
+A K ++ + + E + +KL++ +V+L D + +L+ + +L
Sbjct: 38 FAAKIINTKKLSARDFQKLEREARICRKLQHPN-IVRLHDSIQEESFHYLVFDLVTGGEL 96
Query: 556 SQVLTQRSKIPFDTEFVRYH-FQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKI 610
+ + R F +E H Q++++ + H IVH DLKP N + +K+
Sbjct: 97 FEDIVARE---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKL 153
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG+A V D GTP Y++PE L K KP D+W+CG
Sbjct: 154 ADFGLAIEVNDSEA---WHGFAGTPGYLSPEVL------------KKDPYSKPVDIWACG 198
Query: 671 CILYQMVYGKPPYGTFQGNNRLYA-IMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
ILY ++ G PP+ + +RLYA I P PE D TV P I S L N
Sbjct: 199 VILYILLVGYPPFWD-EDQHRLYAQIKAGAYDYPSPEWD---TVTPEAK-SLIDSMLTVN 253
Query: 730 PISRVTIDQLL 740
P R+T DQ L
Sbjct: 254 PKKRITADQAL 264
>CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 350
Score = 77.4 bits (189), Expect = 8e-14
Identities = 73/251 (29%), Positives = 111/251 (44%), Gaps = 31/251 (12%)
Query: 497 YALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DL 555
+A K ++ + + E + +KL++ +V+L D + +L+ + +L
Sbjct: 38 FAAKIINTKKLSARDFQKLEREARICRKLQHPN-IVRLHDSIQEESFHYLVFDLVTGGEL 96
Query: 556 SQVLTQRSKIPFDTEFVRYH-FQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKI 610
+ + R F +E H Q++++ + H IVH DLKP N + +K+
Sbjct: 97 FEDIVARE---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKL 153
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG+A V D GTP Y++PE L K KP D+W+CG
Sbjct: 154 ADFGLAIEVNDSEA---WHGFAGTPGYLSPEVL------------KKDPYSKPVDIWACG 198
Query: 671 CILYQMVYGKPPYGTFQGNNRLYA-IMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
ILY ++ G PP+ + +RLYA I P PE D TV P I S L N
Sbjct: 199 VILYILLVGYPPFWD-EDQHRLYAQIKAGAYDYPSPEWD---TVTPEAK-SLIDSMLTVN 253
Query: 730 PISRVTIDQLL 740
P R+T DQ L
Sbjct: 254 PKKRITADQAL 264
>CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 77.4 bits (189), Expect = 8e-14
Identities = 73/251 (29%), Positives = 111/251 (44%), Gaps = 31/251 (12%)
Query: 497 YALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DL 555
+A K ++ + + E + +KL++ +V+L D + +L+ + +L
Sbjct: 38 FAAKIINTKKLSARDFQKLEREARICRKLQHPN-IVRLHDSIQEESFHYLVFDLVTGGEL 96
Query: 556 SQVLTQRSKIPFDTEFVRYH-FQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKI 610
+ + R F +E H Q++++ + H IVH DLKP N + +K+
Sbjct: 97 FEDIVARE---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKL 153
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG+A V D GTP Y++PE L K KP D+W+CG
Sbjct: 154 ADFGLAIEVNDSEA---WHGFAGTPGYLSPEVL------------KKDPYSKPVDIWACG 198
Query: 671 CILYQMVYGKPPYGTFQGNNRLYA-IMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
ILY ++ G PP+ + +RLYA I P PE D TV P I S L N
Sbjct: 199 VILYILLVGYPPFWD-EDQHRLYAQIKAGAYDYPSPEWD---TVTPEAK-SLIDSMLTVN 253
Query: 730 PISRVTIDQLL 740
P R+T DQ L
Sbjct: 254 PKKRITADQAL 264
>CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 77.4 bits (189), Expect = 8e-14
Identities = 73/251 (29%), Positives = 111/251 (44%), Gaps = 31/251 (12%)
Query: 497 YALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DL 555
+A K ++ + + E + +KL++ +V+L D + +L+ + +L
Sbjct: 38 FAAKIINTKKLSARDFQKLEREARICRKLQHPN-IVRLHDSIQEESFHYLVFDLVTGGEL 96
Query: 556 SQVLTQRSKIPFDTEFVRYH-FQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKI 610
+ + R F +E H Q++++ + H IVH DLKP N + +K+
Sbjct: 97 FEDIVARE---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKL 153
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG+A V D GTP Y++PE L K KP D+W+CG
Sbjct: 154 ADFGLAIEVNDSEA---WHGFAGTPGYLSPEVL------------KKDPYSKPVDIWACG 198
Query: 671 CILYQMVYGKPPYGTFQGNNRLYA-IMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
ILY ++ G PP+ + +RLYA I P PE D TV P I S L N
Sbjct: 199 VILYILLVGYPPFWD-EDQHRLYAQIKAGAYDYPSPEWD---TVTPEAK-SLIDSMLTVN 253
Query: 730 PISRVTIDQLL 740
P R+T DQ L
Sbjct: 254 PKKRITADQAL 264
>CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 518
Score = 77.4 bits (189), Expect = 8e-14
Identities = 73/251 (29%), Positives = 111/251 (44%), Gaps = 31/251 (12%)
Query: 497 YALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DL 555
+A K ++ + + E + +KL++ +V+L D + +L+ + +L
Sbjct: 38 FAAKIINTKKLSARDFQKLEREARICRKLQHPN-IVRLHDSIQEESFHYLVFDLVTGGEL 96
Query: 556 SQVLTQRSKIPFDTEFVRYH-FQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKI 610
+ + R F +E H Q++++ + H IVH DLKP N + +K+
Sbjct: 97 FEDIVARE---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKL 153
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG+A V D GTP Y++PE L K KP D+W+CG
Sbjct: 154 ADFGLAIEVNDSEA---WHGFAGTPGYLSPEVL------------KKDPYSKPVDIWACG 198
Query: 671 CILYQMVYGKPPYGTFQGNNRLYA-IMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
ILY ++ G PP+ + +RLYA I P PE D TV P I S L N
Sbjct: 199 VILYILLVGYPPFWD-EDQHRLYAQIKAGAYDYPSPEWD---TVTPEAK-SLIDSMLTVN 253
Query: 730 PISRVTIDQLL 740
P R+T DQ L
Sbjct: 254 PKKRITADQAL 264
>CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 77.4 bits (189), Expect = 8e-14
Identities = 73/251 (29%), Positives = 111/251 (44%), Gaps = 31/251 (12%)
Query: 497 YALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DL 555
+A K ++ + + E + +KL++ +V+L D + +L+ + +L
Sbjct: 38 FAAKIINTKKLSARDFQKLEREARICRKLQHPN-IVRLHDSIQEESFHYLVFDLVTGGEL 96
Query: 556 SQVLTQRSKIPFDTEFVRYH-FQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKI 610
+ + R F +E H Q++++ + H IVH DLKP N + +K+
Sbjct: 97 FEDIVARE---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKL 153
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG+A V D GTP Y++PE L K KP D+W+CG
Sbjct: 154 ADFGLAIEVNDSEA---WHGFAGTPGYLSPEVL------------KKDPYSKPVDIWACG 198
Query: 671 CILYQMVYGKPPYGTFQGNNRLYA-IMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
ILY ++ G PP+ + +RLYA I P PE D TV P I S L N
Sbjct: 199 VILYILLVGYPPFWD-EDQHRLYAQIKAGAYDYPSPEWD---TVTPEAK-SLIDSMLTVN 253
Query: 730 PISRVTIDQLL 740
P R+T DQ L
Sbjct: 254 PKKRITADQAL 264
>CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 482
Score = 77.4 bits (189), Expect = 8e-14
Identities = 73/251 (29%), Positives = 111/251 (44%), Gaps = 31/251 (12%)
Query: 497 YALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DL 555
+A K ++ + + E + +KL++ +V+L D + +L+ + +L
Sbjct: 38 FAAKIINTKKLSARDFQKLEREARICRKLQHPN-IVRLHDSIQEESFHYLVFDLVTGGEL 96
Query: 556 SQVLTQRSKIPFDTEFVRYH-FQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKI 610
+ + R F +E H Q++++ + H IVH DLKP N + +K+
Sbjct: 97 FEDIVARE---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKL 153
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG+A V D GTP Y++PE L K KP D+W+CG
Sbjct: 154 ADFGLAIEVNDSEA---WHGFAGTPGYLSPEVL------------KKDPYSKPVDIWACG 198
Query: 671 CILYQMVYGKPPYGTFQGNNRLYA-IMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
ILY ++ G PP+ + +RLYA I P PE D TV P I S L N
Sbjct: 199 VILYILLVGYPPFWD-EDQHRLYAQIKAGAYDYPSPEWD---TVTPEAK-SLIDSMLTVN 253
Query: 730 PISRVTIDQLL 740
P R+T DQ L
Sbjct: 254 PKKRITADQAL 264
>CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 720
Score = 77.4 bits (189), Expect = 8e-14
Identities = 73/251 (29%), Positives = 111/251 (44%), Gaps = 31/251 (12%)
Query: 497 YALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DL 555
+A K ++ + + E + +KL++ +V+L D + +L+ + +L
Sbjct: 38 FAAKIINTKKLSARDFQKLEREARICRKLQHPN-IVRLHDSIQEESFHYLVFDLVTGGEL 96
Query: 556 SQVLTQRSKIPFDTEFVRYH-FQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKI 610
+ + R F +E H Q++++ + H IVH DLKP N + +K+
Sbjct: 97 FEDIVARE---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKL 153
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG+A V D GTP Y++PE L K KP D+W+CG
Sbjct: 154 ADFGLAIEVNDSEA---WHGFAGTPGYLSPEVL------------KKDPYSKPVDIWACG 198
Query: 671 CILYQMVYGKPPYGTFQGNNRLYA-IMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
ILY ++ G PP+ + +RLYA I P PE D TV P I S L N
Sbjct: 199 VILYILLVGYPPFWD-EDQHRLYAQIKAGAYDYPSPEWD---TVTPEAK-SLIDSMLTVN 253
Query: 730 PISRVTIDQLL 740
P R+T DQ L
Sbjct: 254 PKKRITADQAL 264
>CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 559
Score = 77.4 bits (189), Expect = 8e-14
Identities = 73/251 (29%), Positives = 111/251 (44%), Gaps = 31/251 (12%)
Query: 497 YALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DL 555
+A K ++ + + E + +KL++ +V+L D + +L+ + +L
Sbjct: 38 FAAKIINTKKLSARDFQKLEREARICRKLQHPN-IVRLHDSIQEESFHYLVFDLVTGGEL 96
Query: 556 SQVLTQRSKIPFDTEFVRYH-FQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKI 610
+ + R F +E H Q++++ + H IVH DLKP N + +K+
Sbjct: 97 FEDIVARE---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKL 153
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG+A V D GTP Y++PE L K KP D+W+CG
Sbjct: 154 ADFGLAIEVNDSEA---WHGFAGTPGYLSPEVL------------KKDPYSKPVDIWACG 198
Query: 671 CILYQMVYGKPPYGTFQGNNRLYA-IMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
ILY ++ G PP+ + +RLYA I P PE D TV P I S L N
Sbjct: 199 VILYILLVGYPPFWD-EDQHRLYAQIKAGAYDYPSPEWD---TVTPEAK-SLIDSMLTVN 253
Query: 730 PISRVTIDQLL 740
P R+T DQ L
Sbjct: 254 PKKRITADQAL 264
>At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 646
Score = 77.4 bits (189), Expect = 8e-14
Identities = 65/254 (25%), Positives = 113/254 (43%), Gaps = 36/254 (14%)
Query: 497 YALKRVSFDEF-DESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHD 554
YA K +S + + ++ + EI+++ L V+ + + + L+ME C +
Sbjct: 212 YACKSISKRKLLTDEDVEDVRREIQIMHHLAGHPNVISIKGAYEDVVAVHLVMELCSGGE 271
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKI 610
L + QR + + ++ ++ H ++H DLKP NF+FV +LK
Sbjct: 272 LFDRIIQRGH--YTERKAAELARTIVGVLEACHSLGVMHRDLKPENFLFVSREEDSLLKT 329
Query: 611 IDFGIANAV-PDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
IDFG++ PD + +G+P Y+APE L + + G SDVWS
Sbjct: 330 IDFGLSMFFKPDEVFT----DVVGSPYYVAPEVL-------------RKRYGPESDVWSA 372
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKI---PYPEKDSFGTVIPRTVIDTIRSCL 726
G I+Y ++ G PP+ +++ D+ P+P I + D +R L
Sbjct: 373 GVIVYILLSGVPPFWAETEQGIFEQVLHGDLDFSSDPWPS-------ISESAKDLVRKML 425
Query: 727 ERNPISRVTIDQLL 740
R+P R+T Q+L
Sbjct: 426 VRDPKRRLTAHQVL 439
>At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 547
Score = 77.4 bits (189), Expect = 8e-14
Identities = 61/232 (26%), Positives = 106/232 (45%), Gaps = 34/232 (14%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTEFVRYHF 576
EI+++ L + +V++ + + + L+ME C +L +T+R + +
Sbjct: 146 EIQIMHYLSGQPNIVEIKGAYEDRQSVHLVMELCEGGELFDKITKRGH--YSEKAAAEII 203
Query: 577 QEMIKCVKVVHDADIVHSDLKPANFVF-----VKGMLKIIDFGIANAVPDHTVNIYRDNQ 631
+ ++K V++ H ++H DLKP NF+ MLK DFG++ + + V Y D
Sbjct: 204 RSVVKVVQICHFMGVIHRDLKPENFLLSSKDEASSMLKATDFGVSVFIEEGKV--YEDI- 260
Query: 632 IGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNR 691
+G+ Y+APE L K GK D+WS G ILY ++ G PP+
Sbjct: 261 VGSAYYVAPEVL-------------KRNYGKAIDIWSAGVILYILLCGNPPFWAETDKGI 307
Query: 692 LYAIMNPDVKI---PYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
I+ ++ P+P I + D +R+ L+ +P R T Q+L
Sbjct: 308 FEEILRGEIDFESEPWPS-------ISESAKDLVRNMLKYDPKKRFTAAQVL 352
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 77.4 bits (189), Expect = 8e-14
Identities = 57/191 (29%), Positives = 96/191 (49%), Gaps = 19/191 (9%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQ--RVVKLIDYHMGQGVLFLLMECGE 552
K+ ALK+V FD + S+ EI++L++L++ ++ L+ M L+L+ E E
Sbjct: 158 KIVALKKVRFDNLEPESVRFMAREIQILRRLDHPNIIKLEGLVTSRMSCS-LYLVFEYME 216
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKII 611
HDL+ L I F V+ + Q+++ + H ++H D+K +N + G+LKI
Sbjct: 217 HDLAG-LASHPAIKFSESQVKCYLQQLLHGLDHCHSRGVLHRDIKGSNLLIDNSGVLKIA 275
Query: 612 DFGIANAV-PDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG+A+ P T + +++ T Y PE L+ + G D+WS G
Sbjct: 276 DFGLASFFDPRQTQPL--TSRVVTLWYRPPELLLGAT-----------RYGAAVDLWSAG 322
Query: 671 CILYQMVYGKP 681
CIL ++ GKP
Sbjct: 323 CILAELYAGKP 333
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 77.4 bits (189), Expect = 8e-14
Identities = 68/251 (27%), Positives = 112/251 (44%), Gaps = 30/251 (11%)
Query: 498 ALKRVSFDEF-DESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDL 555
A K +S D + + K EI ++ KL VV L + + + L+ME C +L
Sbjct: 71 ACKSISKDRLVTQDDMKSIKLEIAIMAKLAGHPNVVNLKAVYEEKDSVHLVMELCAGGEL 130
Query: 556 SQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFV----KGMLKII 611
L + + + R F+ +++ VK HD+ IVH DLKP N + +K+
Sbjct: 131 FHKLEKYGR--YSEVRARVLFKHLMQVVKFCHDSGIVHRDLKPENILMATMSSSSPIKLA 188
Query: 612 DFGIANAV-PDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG+A + P ++ +G+P Y+APE L + +DVWS G
Sbjct: 189 DFGLATYIKPGEKLS----GTVGSPFYIAPEVLAG-------------GYNQAADVWSAG 231
Query: 671 CILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNP 730
ILY ++ G PP+ + A+ D++ D+ I D IR L +P
Sbjct: 232 VILYILLSGAPPFWGKTKSKIFDAVRAADLRFSAEPWDN----ITSYAKDLIRGMLCVDP 287
Query: 731 ISRVTIDQLLS 741
R++ D++L+
Sbjct: 288 SQRLSADEVLA 298
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 77.0 bits (188), Expect = 1e-13
Identities = 61/213 (28%), Positives = 94/213 (43%), Gaps = 34/213 (15%)
Query: 494 HKVYALKRVSF--DEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECG 551
H + LK+V DE SI I + ++ Q+V ++DY G G LF L+
Sbjct: 122 HTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEG-GELFSLL--- 177
Query: 552 EHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKI 610
R F +++ E+ ++ +H DI++ DLKP N + K G +KI
Sbjct: 178 ----------RKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKI 227
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG A VPD T + GTP+Y+APE + + K D WS G
Sbjct: 228 TDFGFAKYVPDVTYTL-----CGTPDYIAPEVVSTKPYN------------KSVDWWSFG 270
Query: 671 CILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIP 703
++Y+M+ G P+ I+N ++K P
Sbjct: 271 VLIYEMLAGYTPFYNSNTMKTYENILNAELKFP 303
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 77.0 bits (188), Expect = 1e-13
Identities = 78/300 (26%), Positives = 134/300 (44%), Gaps = 53/300 (17%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKL-----ENKQRVVK----LIDYHMGQGVLF 545
++ ALK+V D E EI++L++L N + +V +D+ +G +
Sbjct: 751 ELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFY 810
Query: 546 LLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK 605
L+ E +HDL +L + + F + ++ +++++ ++ H + +H D+K +N +
Sbjct: 811 LVFEYMDHDLMGLL-ESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNN 869
Query: 606 -GMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPS 664
G +K+ DFG+A Y N++ T Y PE L+ GE+ +
Sbjct: 870 SGQIKLADFGLARLYNSEESRPYT-NKVITLWYRPPELLL--------GEE---RYTPAI 917
Query: 665 DVWSCGCILYQMVYGKPPYGTFQGNNRLYAI-------------MNPDV-KIPY-----P 705
DVWSCGCIL ++ KP FQ N L + + PDV K+PY P
Sbjct: 918 DVWSCGCILGELFTKKP---IFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKP 974
Query: 706 EK-------DSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALINPVTVTKFFIHDL 758
+K + F + IP +D + L +P R T +Q L + V ++K DL
Sbjct: 975 KKQYRRRLREEF-SFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDL 1033
>Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1152
Score = 77.0 bits (188), Expect = 1e-13
Identities = 69/241 (28%), Positives = 113/241 (46%), Gaps = 24/241 (9%)
Query: 505 DEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRS 563
D E ++ + EI++L ++ +VKL+D + L++L+E C + V+ +
Sbjct: 66 DTKSEEELEDYMVEIDILASCDHPN-IVKLLDAFYYENNLWILIEFCAGGAVDAVMLELE 124
Query: 564 KIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDH 622
+ P ++ ++ + + +HD I+H DLK N +F + G +K+ DFG+ +A
Sbjct: 125 R-PLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGV-SAKNTR 182
Query: 623 TVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPP 682
T+ RD+ IGTP +MAPE V M T D +DVWS G L +M +PP
Sbjct: 183 TIQ-RRDSFIGTPYWMAPE--VVMCETSKDR-----PYDYKADVWSLGITLIEMAEIEPP 234
Query: 683 YGTFQGNNRLYAIMN---PDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQL 739
+ L I P + P +F D ++ CLE+N +R T QL
Sbjct: 235 HHELNPMRVLLKIAKSEPPTLAQPSRWSSNFK--------DFLKKCLEKNVDARWTTSQL 286
Query: 740 L 740
L
Sbjct: 287 L 287
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 77.0 bits (188), Expect = 1e-13
Identities = 70/311 (22%), Positives = 144/311 (45%), Gaps = 54/311 (17%)
Query: 497 YALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDL 555
+A+K+V+ ++ S++ + E+ +LK +++ + ++ L ++L+ME C + +L
Sbjct: 142 WAIKKVNKEKAGSSAVKLLEREVNILKSVKH-EHIIHLEQVFETPKKMYLVMELCEDGEL 200
Query: 556 SQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGML------- 608
++L ++ F R+ Q + + +H+ DIVH DLK N + ++
Sbjct: 201 KEILDRKGH--FSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEIN 258
Query: 609 ---KIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSD 665
K+ DFG+A + + + GTP YMAPE + A ++++ D
Sbjct: 259 LNIKVTDFGLAVKKQSRSEAMLQAT-CGTPIYMAPEVISAHDYSQQ------------CD 305
Query: 666 VWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSC 725
+WS G ++Y ++ G+PP+ +L+ ++ + F + ++ D +S
Sbjct: 306 IWSIGVVMYMLLRGEPPF-LASSEEKLFELIRKG-------ELHFENAVWNSISDCAKSV 357
Query: 726 LER----NPISRVTIDQL-----LSGALINPVTVTKFFIHDLIKNAVNYGCDQKHVNNER 776
L++ +P R+T +L L+G ++ V T + +++K N N E
Sbjct: 358 LKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTN--VLEMMKEWKN--------NPES 407
Query: 777 VEELSEDVWNK 787
VEE + + NK
Sbjct: 408 VEENTTEEKNK 418
>CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 270
Score = 77.0 bits (188), Expect = 1e-13
Identities = 53/176 (30%), Positives = 84/176 (47%), Gaps = 23/176 (13%)
Query: 531 VVKLIDYHMGQGVLFLLMEC--GEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHD 588
+VK+ L+++ME G S + RS F R++ E++ ++ +H
Sbjct: 22 IVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRS---FSNSMARFYASEIVCALEYIHS 78
Query: 589 ADIVHSDLKPANFVFVK-GMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMN 647
IV+ DLKP N + K G +K+ DFG A + D T I GTP+Y+APE+L
Sbjct: 79 LGIVYRDLKPENLMLSKEGHIKMADFGFAKELRDRTYTI-----CGTPDYLAPESL---- 129
Query: 648 FTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIP 703
A+ K D W+ G ++Y+M+ GKPP+ + AI+ +K P
Sbjct: 130 --------ARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFP 177
>CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1228
Score = 77.0 bits (188), Expect = 1e-13
Identities = 67/311 (21%), Positives = 136/311 (43%), Gaps = 32/311 (10%)
Query: 493 DHKVYAL-KRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-C 550
D K++A K + E +E ++ F EIE+L + + ++ L + + L +L+E C
Sbjct: 56 DPKLFAASKSIEIQEGEE--LEDFLVEIEILSECKGHPVMLGLYSTYFFENKLTMLLEFC 113
Query: 551 GEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLK 609
G + ++ + + + + +RY + +K +H +++H DLK N + + G ++
Sbjct: 114 GGGAVDNIIVELGHVLKEDQ-IRYIGYYVCDALKWLHSQNVIHRDLKAGNILLTQDGQVR 172
Query: 610 IIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
+ DFG++ + RD IGTP +MAPE + F + SD+WS
Sbjct: 173 LADFGVSAKLKSEREK--RDTFIGTPYWMAPEVMACETFKDQPYDCI-------SDIWSF 223
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSF--GTVIPRTVIDTIRSCLE 727
G L +M G+PP+ ++M +K+ E + + R+ D + CL
Sbjct: 224 GITLIEMAQGEPPHSD-------VSVMRVIIKVQKSEPPTLLQPSHWTRSFSDILTRCLV 276
Query: 728 RNPISRVTIDQLLSGALINPVTVTKFFIHDLI--------KNAVNYGCDQKHVNNERVEE 779
++P +R ++ + I DL+ + V G ++ ++ + +
Sbjct: 277 KDPRNRPPAAEIFKHQWFQNAPSKRKMIMDLLAEMYADVQEEVVIDGDEESVAGSDEISQ 336
Query: 780 LSEDVWNKLAE 790
D W+ ++
Sbjct: 337 RRGDSWSSASD 347
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 77.0 bits (188), Expect = 1e-13
Identities = 53/176 (30%), Positives = 84/176 (47%), Gaps = 23/176 (13%)
Query: 531 VVKLIDYHMGQGVLFLLMEC--GEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHD 588
+VK+ L+++ME G S + RS F R++ E++ ++ +H
Sbjct: 123 IVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRS---FSNSMARFYASEIVCALEYIHS 179
Query: 589 ADIVHSDLKPANFVFVK-GMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMN 647
IV+ DLKP N + K G +K+ DFG A + D T I GTP+Y+APE+L
Sbjct: 180 LGIVYRDLKPENLMLSKEGHIKMADFGFAKELRDRTYTI-----CGTPDYLAPESL---- 230
Query: 648 FTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIP 703
A+ K D W+ G ++Y+M+ GKPP+ + AI+ +K P
Sbjct: 231 --------ARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFP 278
>At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 610
Score = 77.0 bits (188), Expect = 1e-13
Identities = 66/252 (26%), Positives = 111/252 (43%), Gaps = 57/252 (22%)
Query: 509 ESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMEC---GEHDLSQVLTQRSKI 565
+ ++ + EI+++ L V+ + + + L+MEC GE
Sbjct: 189 DEDVEDVRREIQIMHHLAGHPNVISIKGAYEDVVAVHLVMECCAGGEL------------ 236
Query: 566 PFDTEFVRYHFQE---------MIKCVKVVHDADIVHSDLKPANFVFVK----GMLKIID 612
FD R H+ E ++ V+ H ++H DLKP NF+FV +LK ID
Sbjct: 237 -FDRIIQRGHYTERKAAELTRTIVGVVEACHSLGVMHRDLKPENFLFVSKHEDSLLKTID 295
Query: 613 FGIANAV-PDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGC 671
FG++ PD +++ D +G+P Y+APE L + + G +DVWS G
Sbjct: 296 FGLSMFFKPD---DVFTD-VVGSPYYVAPEVL-------------RKRYGPEADVWSAGV 338
Query: 672 ILYQMVYGKPPYGTFQGNNRLYAIMNPDVKI---PYPEKDSFGTVIPRTVIDTIRSCLER 728
I+Y ++ G PP+ +++ D+ P+P I + D +R L R
Sbjct: 339 IVYILLSGVPPFWAETEQGIFEQVLHGDLDFSSDPWPS-------ISESAKDLVRKMLVR 391
Query: 729 NPISRVTIDQLL 740
+P R+T Q+L
Sbjct: 392 DPKKRLTAHQVL 403
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 77.0 bits (188), Expect = 1e-13
Identities = 63/240 (26%), Positives = 106/240 (43%), Gaps = 44/240 (18%)
Query: 513 DGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DLSQVLTQRSKIPFDTEF 571
+ K EI ++++L + +VKL + + +F ME + +L +++ ++ D
Sbjct: 65 NNIKREISIMRRLSHPN-IVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLS- 122
Query: 572 VRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDFGIANAVPDHTVNIYRDN 630
R +FQ++I V H + H DLKP N + + G LK+ DFG++ +
Sbjct: 123 -RRYFQQLISAVGYCHARGVYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHT 181
Query: 631 QIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYG------ 684
GTP Y+APE L + G DVWSCG +L+ +V G P+
Sbjct: 182 LCGTPAYVAPEILSKKGYE-----------GAKVDVWSCGIVLFVLVAGYLPFNDPNVMN 230
Query: 685 ----TFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
++G R M+PD+K + L+ NP +R+TID++L
Sbjct: 231 MYKKIYKGEYRFPRWMSPDLK------------------RFVSRLLDINPETRITIDEIL 272
>7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 835
Score = 77.0 bits (188), Expect = 1e-13
Identities = 72/256 (28%), Positives = 115/256 (44%), Gaps = 51/256 (19%)
Query: 518 EIELLKKLE--NKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTEFVRY 574
EI++LK+L + + VV L+D Q + L+ME C DL+ L+ + + DT VR
Sbjct: 55 EIKILKELTELHHENVVALLDCKESQDCVSLVMEYCNGGDLADYLSVKGTLSEDT--VRL 112
Query: 575 HFQEMIKCVKVVHDADIVHSDLKPANFVFV-----------KGMLKIIDFGIANAVPDHT 623
++ +K ++ IVH DLKP N + K LKI DFG A + +
Sbjct: 113 FLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGKTLPAPSKITLKIADFGFARFLNEGA 172
Query: 624 VNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPY 683
+ G+P YMAPE ++++ + +D+WS G I+YQ + GK P+
Sbjct: 173 MAA---TLCGSPMYMAPEVIMSLQYDSK------------ADLWSLGTIVYQCLTGKAPF 217
Query: 684 GTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRS----CLERNPISRVT---- 735
YA ++K Y + + IP V +R L RN R++
Sbjct: 218 ---------YAQTPNELKSYYEQNANLAPKIPSGVSPDLRDLLLCLLRRNSKDRISYESF 268
Query: 736 -IDQLLSG--ALINPV 748
+ + L G A ++PV
Sbjct: 269 FVHRFLQGKKAAVSPV 284
>7291742_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1539
Score = 77.0 bits (188), Expect = 1e-13
Identities = 65/252 (25%), Positives = 115/252 (44%), Gaps = 17/252 (6%)
Query: 495 KVYALKRVS-FDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME--CG 551
KVYA+K ++ ++ + F+ E ++L ++Q + L L+L+M+ CG
Sbjct: 124 KVYAMKILNKWEMLKRAETACFREERDVLV-FGDRQWITNLHYAFQDNINLYLVMDYYCG 182
Query: 552 EHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKI 610
L+ + K+P D +++ EMI + +H VH D+KP N + K G +++
Sbjct: 183 GDLLTLLSKFEDKLPED--MAKFYITEMILAINSIHQIRYVHRDIKPDNVLLDKRGHVRL 240
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG + D + + +GTP+Y++PE L AM E K + G D WS G
Sbjct: 241 ADFGSCLRL-DKDGTVQSNVAVGTPDYISPEILRAM-------EDGKGRYGTECDWWSLG 292
Query: 671 CILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRS--CLER 728
+Y+M+YG+ P+ IMN P +++ + T D + C+
Sbjct: 293 VCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQETLNYKVSETSQDLLCKLICIPE 352
Query: 729 NPISRVTIDQLL 740
N + + I +
Sbjct: 353 NRLGQNGIQDFM 364
>YDR523c [T] KOG0201 Serine/threonine protein kinase
Length = 490
Score = 76.6 bits (187), Expect = 1e-13
Identities = 70/269 (26%), Positives = 118/269 (43%), Gaps = 25/269 (9%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEH 553
++ A+K V+ + DE I+ EI L +L++ + I + ++++ME CG
Sbjct: 42 EIVAIKVVNLEHSDED-IELLAQEIFFLAELKSPL-ITNYIATMLEDVSMWIVMEYCGGG 99
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIID 612
S +L + E V + E+ +K +H+ +H D+K AN + +GM+K+ D
Sbjct: 100 SCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGD 159
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG++ + + RD +GTP +MAPE + DG K +D+WS G
Sbjct: 160 FGVSGHIRS---TLKRDTFVGTPYWMAPEVVCC----EVDGYNEK------ADIWSLGIT 206
Query: 673 LYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPIS 732
Y+++ G PP Y M +P + D + CL + P
Sbjct: 207 TYELLKGLPPLSK-------YDPMKVMTNLPKRKPPKLQGPFSDAAKDFVAGCLVKTPAD 259
Query: 733 RVTIDQLLSGALINPVTVTKFFIH-DLIK 760
R + LLS + +T+T DLIK
Sbjct: 260 RPSAYNLLSFEFVKNITITNLKSDVDLIK 288
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 76.6 bits (187), Expect = 1e-13
Identities = 46/144 (31%), Positives = 73/144 (49%), Gaps = 19/144 (13%)
Query: 567 FDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVN 625
FD R++ E++ ++ +H I+H DLKP N + + M ++I DFG A + +
Sbjct: 177 FDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQ 236
Query: 626 IYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGT 685
++ +GT Y++PE L + K SD+W+ GCI+YQ+V G PP+
Sbjct: 237 ARANSFVGTAQYVSPELLTEKSAC------------KSSDLWALGCIIYQLVAGLPPFRA 284
Query: 686 FQGNNRLYAIMNPDVKIPY--PEK 707
GN Y I +K+ Y PEK
Sbjct: 285 --GNE--YLIFQKIIKLEYDFPEK 304
>At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 76.6 bits (187), Expect = 1e-13
Identities = 73/266 (27%), Positives = 126/266 (46%), Gaps = 39/266 (14%)
Query: 511 SIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMEC--GEHDLSQVLTQRSKIPFD 568
SI+ + E++LLK L + +VK D + +F++ME G L ++L + + P +
Sbjct: 187 SIEDVRREVKLLKALSGHRHMVKFYDVYEDADNVFVVMELCEGGELLDRILARGGRYP-E 245
Query: 569 TEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKIIDFGIANAVP-DHT 623
+ R Q ++ H +VH DLKP NF+F +LK+IDFG+++ + D
Sbjct: 246 VDAKRILVQ-ILSATAFFHLQGVVHRDLKPENFLFTSRNEDAILKVIDFGLSDFIRYDQR 304
Query: 624 VNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYG-KPP 682
+N + +G+ Y+APE L T +D+WS G I Y ++ G +P
Sbjct: 305 LN----DVVGSAYYVAPEVLHRSYSTE-------------ADMWSIGVISYILLCGSRPF 347
Query: 683 YG-TFQGNNRLYAIMNPDVK-IPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
YG T R NP+ + +P+P I T D ++ L ++ R+T Q L
Sbjct: 348 YGRTESAIFRCVLRANPNFEDMPWPS-------ISPTAKDFVKRLLNKDHRKRMTAAQAL 400
Query: 741 SGALI---NPVTVTKFFIHDLIKNAV 763
+ + NP + F ++ L+K+ +
Sbjct: 401 AHPWLRDENPGLLLDFSVYKLVKSYI 426
>At1g63700 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 883
Score = 76.6 bits (187), Expect = 1e-13
Identities = 59/219 (26%), Positives = 97/219 (43%), Gaps = 43/219 (19%)
Query: 535 IDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHS 594
++Y G + LL E G+ F +R + Q+++ + +H + VH
Sbjct: 479 LEYVSGGSIYKLLQEYGQ--------------FGENAIRNYTQQILSGLAYLHAKNTVHR 524
Query: 595 DLKPANF-VFVKGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDG 653
D+K AN V G +K+ DFG+A + + + + G+P +MAPE + N +
Sbjct: 525 DIKGANILVDPHGRVKVADFGMAKHITAQSGPL---SFKGSPYWMAPEVIKNSNGSN--- 578
Query: 654 EQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMN----PDVKIPYPEKDS 709
D+WS GC + +M KPP+ ++G ++ I N PD+ E+
Sbjct: 579 --------LAVDIWSLGCTVLEMATTKPPWSQYEGVPAMFKIGNSKELPDIPDHLSEEGK 630
Query: 710 FGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALINPV 748
D +R CL+RNP +R T QLL A + V
Sbjct: 631 ----------DFVRKCLQRNPANRPTAAQLLDHAFVRNV 659
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 76.6 bits (187), Expect = 1e-13
Identities = 74/283 (26%), Positives = 127/283 (44%), Gaps = 53/283 (18%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHD 554
++ A+K++ + DE EI LLK+L++ + +V L D M + ++L+ E D
Sbjct: 28 QIVAMKKIRLESDDEGVPSTAIREISLLKELKH-ENIVCLEDVLMEENRIYLIFEFLSMD 86
Query: 555 LSQVLTQRSKIPFD----TEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLK 609
L + + +P D +E VR + ++ + H ++H DLKP N + K G++K
Sbjct: 87 LKKYM---DSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQNLLIDKSGLIK 143
Query: 610 IIDFGIANA--VPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVW 667
+ DFG+ + +P V IY ++I T Y APE L+ + P D+W
Sbjct: 144 VADFGLGRSFGIP---VRIY-THEIVTLWYRAPEVLLGSP-----------RYSCPVDIW 188
Query: 668 SCGCILYQMVYGKPPYGTFQGNN------RLYAIMN-------------PDVKIPYP--- 705
S GCI +M KP FQG++ R++ I+ PD K +P
Sbjct: 189 SIGCIFAEMATRKP---LFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWS 245
Query: 706 --EKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALIN 746
+ + + ID I+ L +P+ R++ +L N
Sbjct: 246 TNQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYFN 288
>7292656 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 638
Score = 76.6 bits (187), Expect = 1e-13
Identities = 65/231 (28%), Positives = 104/231 (44%), Gaps = 26/231 (11%)
Query: 509 ESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFD 568
+SS K EI +L E + +V L H + LL+E Q + + +
Sbjct: 39 QSSDKEIKHEIAVLMLCEGEDNIVNLNAVHETRSDTALLLELATGGELQTILDNEECLTE 98
Query: 569 TEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF----VKGMLKIIDFGIANAVPDHTV 624
+ R+ +E++K +K +HD I H DLKP N + ++ LK+ DFGI+ V +
Sbjct: 99 AQ-ARHCMREVLKALKFLHDRSIAHLDLKPQNILLAGERIEDGLKLCDFGISRVVCE--- 154
Query: 625 NIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYG 684
I GTP+Y+APE L + +D+WS G + Y ++ G P+G
Sbjct: 155 GINVREMAGTPDYVAPEVL------------QYEPLSLLTDIWSVGVLTYVLLSGFSPFG 202
Query: 685 TFQGNNRLYAIMN-PDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRV 734
G+ + +N + +P+ + FG V P ID IR L P R+
Sbjct: 203 ---GDTKQETFLNISQCALTFPD-NLFGGVSP-VAIDFIRRALRIKPNDRM 248
>At4g08470 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 560
Score = 76.3 bits (186), Expect = 2e-13
Identities = 73/278 (26%), Positives = 121/278 (43%), Gaps = 33/278 (11%)
Query: 470 TAYEKVELLXXXXXXXXXXXXXXDHKVYALKRVSFDEFD---ESSIDGFKGEIELLKKLE 526
T++ K +LL D +A+K VS + + I +GEI LL +L+
Sbjct: 301 TSWLKGQLLGRGSYASVYEAISEDGDFFAVKEVSLLDKGIQAQECIQQLEGEIALLSQLQ 360
Query: 527 NKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVV 586
+ Q +V+ L++ +E Q L +R ++ + V + ++++ + +
Sbjct: 361 H-QNIVRYRGTAKDVSKLYIFLELVTQGSVQKLYERYQLSYTV--VSLYTRQILAGLNYL 417
Query: 587 HDADIVHSDLKPANF-VFVKGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVA 645
HD VH D+K AN V G +K+ DFG+A A + + + GT +MAPE +
Sbjct: 418 HDKGFVHRDIKCANMLVDANGTVKLADFGLAEASKFNDIMSCK----GTLFWMAPEVI-- 471
Query: 646 MNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMN---PDVKI 702
N +DG G P+D+WS GC + +M G+ PY + + I PDV
Sbjct: 472 -NRKDSDGN------GSPADIWSLGCTVLEMCTGQIPYSDLKPIQAAFKIGRGTLPDVP- 523
Query: 703 PYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
+ I +CL+ NP R T +LL
Sbjct: 524 ---------DTLSLDARHFILTCLKVNPEERPTAAELL 552
>At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 575
Score = 76.3 bits (186), Expect = 2e-13
Identities = 55/199 (27%), Positives = 92/199 (45%), Gaps = 24/199 (12%)
Query: 495 KVYALKRVSFDEFD-ESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGE 552
K YA K + E + K EI+++ + + +V++ + + ++ME CG
Sbjct: 46 KSYACKSIPKRTLSSEEEKEAVKTEIQIMDHVSGQPNIVQIKGSYEDNNSIHIVMELCGG 105
Query: 553 HDLSQVLTQ--RSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF----VKG 606
+L + +S + + F+ ++ VK+ H D+VH DLKP NF+F
Sbjct: 106 GELFDKIDALVKSHSYYSEKDAAGIFRSIVNAVKICHSLDVVHRDLKPENFLFSSKDENA 165
Query: 607 MLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDV 666
MLK IDFG + + + + +G+ Y+APE L + GK D+
Sbjct: 166 MLKAIDFGCSVYIKEGKT---FERVVGSKYYIAPEVL-------------EGSYGKEIDI 209
Query: 667 WSCGCILYQMVYGKPPYGT 685
WS G ILY ++ G PP+ T
Sbjct: 210 WSAGVILYILLSGVPPFQT 228
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 76.3 bits (186), Expect = 2e-13
Identities = 59/215 (27%), Positives = 103/215 (47%), Gaps = 17/215 (7%)
Query: 471 AYEKVELLXXXXXXXXXXXXXXDH-KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQ 529
A+EK+E + + ++ ALK+V FD F+ S+ EI +L+KL N
Sbjct: 130 AFEKLEKIGQGTYSSVFRARETETGRIVALKKVRFDNFEPESVRFMAREILILRKL-NHP 188
Query: 530 RVVKL--IDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVH 587
++KL I + L+ E EHDL+ +L+ I F T ++ + ++++ + H
Sbjct: 189 NIIKLEGIVTSKLSCSIHLVFEYMEHDLTGLLSS-PDIDFTTPQIKCYMKQLLSGLDHCH 247
Query: 588 DADIVHSDLKPAN-FVFVKGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAM 646
++H D+K +N V +G+LK+ DFG+AN +++ T Y PE L+
Sbjct: 248 ARGVMHRDIKGSNLLVNNEGILKVADFGLANFCNASGNKQPLTSRVVTLWYRPPELLLGA 307
Query: 647 NFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKP 681
+ G D+WS GC+ +++ GKP
Sbjct: 308 T-----------EYGASVDLWSVGCVFAELLIGKP 331
>7294265 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2139
Score = 76.3 bits (186), Expect = 2e-13
Identities = 57/193 (29%), Positives = 85/193 (43%), Gaps = 33/193 (17%)
Query: 566 PFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDFGIAN-AVPDHT 623
P + R++F E + V+ +H IVH DLKP N + G +K+ DFG++ +
Sbjct: 929 PLPADMARFYFAETVLAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLA 988
Query: 624 VNIYR-----------DNQI-GTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGC 671
N+Y D Q+ GTP Y+APE ++ + GKP D WS G
Sbjct: 989 TNLYEGYIDSETRQFSDKQVYGTPEYIAPEVILRQGY------------GKPVDWWSMGI 1036
Query: 672 ILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPI 731
ILY+ + G P+ +N D++ P DS + D I L++NP
Sbjct: 1037 ILYEFLIGCVPFFGETTEELFAHTVNDDIEWP----DSEDWPVQAEAKDIISQLLQQNPR 1092
Query: 732 SRVTIDQLLSGAL 744
R+ SGAL
Sbjct: 1093 DRLGTQ---SGAL 1102
>Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1530
Score = 76.3 bits (186), Expect = 2e-13
Identities = 50/181 (27%), Positives = 86/181 (46%), Gaps = 22/181 (12%)
Query: 526 ENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKV 585
+++ + ++DY++G +L LL + + K+P D R++ EM+ +
Sbjct: 144 QDENHLYLVMDYYVGGDLLTLLSKFED-----------KLPED--MARFYIGEMVLAIDS 190
Query: 586 VHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLV 644
+H VH D+KP N + V G +++ DFG + D + +GTP+Y++PE L
Sbjct: 191 IHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGT-VQSSVAVGTPDYISPEILQ 249
Query: 645 AMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPY 704
AM E K G D WS G +Y+M+YG+ P+ IMN + + +
Sbjct: 250 AM-------EDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQF 302
Query: 705 P 705
P
Sbjct: 303 P 303
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 75.9 bits (185), Expect = 2e-13
Identities = 67/236 (28%), Positives = 105/236 (44%), Gaps = 26/236 (11%)
Query: 521 LLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DLSQVLTQRSKIPFDTEFVRYHFQEM 579
++ KL + V+ L D L+L++E E +L +L +P + E + F+++
Sbjct: 79 VIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLP-EREAINC-FRQI 136
Query: 580 IKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVNIYRDNQIGTPNYM 638
I + H IVH DLKP N + +KI DFG+A D + + G+P+Y
Sbjct: 137 IIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADL---LETSCGSPHYA 193
Query: 639 APETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNR--LYAIM 696
APE + + + G SDVWSCG IL+ ++ G+ P+ GN R L +
Sbjct: 194 APEIVSGLPYE-----------GFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQ 242
Query: 697 NPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALINPVTVTK 752
++P T I R D I L +P R+ I +LS L+ K
Sbjct: 243 KGQFEMPN------DTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIK 292
>SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase
Length = 652
Score = 75.9 bits (185), Expect = 2e-13
Identities = 68/256 (26%), Positives = 114/256 (43%), Gaps = 36/256 (14%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYH----MGQGVLFLLMECGEH 553
A+K ++ D DE + + E+ +L +L+ V +I YH +G + ++ C
Sbjct: 37 AIKILNLDT-DEDEVSDIQKEVAVLSELKQSD-VENIIKYHGSYLVGTNLWIIMDYCHG- 93
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLKIID 612
V T P + +E ++ +K +H A I+H D+K AN V + G +K+ D
Sbjct: 94 --GSVRTLMEAGPISEPCISLILRETLQALKFIHHAGIIHRDIKAANILVSMSGNVKLCD 151
Query: 613 FGIANAVPDHTVNIYRDNQ---IGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
FG+A +NI R + IGTP +MAPE + DG++ +D+WS
Sbjct: 152 FGVA-----AELNINRRKRITFIGTPYWMAPEVI-------RDGQE----YNVMADIWSL 195
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
G Y++ G PP+ +Y I + P +F ++ + I SCL+
Sbjct: 196 GITAYEIATGSPPHAKEDPFRAVYLIAH---TAPPRLNGNFSALLK----EFIASCLQDV 248
Query: 730 PISRVTIDQLLSGALI 745
P R+ +LL I
Sbjct: 249 PQRRLDSSELLKSKFI 264
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 75.9 bits (185), Expect = 2e-13
Identities = 64/272 (23%), Positives = 120/272 (43%), Gaps = 37/272 (13%)
Query: 496 VYALKRVSFDEFDESSID----GFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECG 551
V+ ++V+ D++ +D G + KL +V+L + Q L+L++E G
Sbjct: 36 VFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELG 95
Query: 552 EHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK--GMLK 609
+ + + + + + +F +++ + H +VH DLKP N VF + G++K
Sbjct: 96 DEGDMFDYIMKHEEGLNEDLPKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVK 155
Query: 610 IIDFGIANAV-PDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWS 668
+ DFG +N P + G+ Y APE L+ + D+WS
Sbjct: 156 LTDFGFSNKFQPGKKLT----TSCGSLAYSAPEILLGDEYD-----------APAVDIWS 200
Query: 669 CGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLER 728
G IL+ +V G+PP+ + L IM+ +P + + + D I L+R
Sbjct: 201 LGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVP--------SHVSKECKDLITRMLQR 252
Query: 729 NPISRVTIDQL-----LSGALINPVTVTKFFI 755
+P R +++++ L G ++P TK+ I
Sbjct: 253 DPKRRASLEEIENHPWLQG--VDPSPATKYNI 282
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 75.9 bits (185), Expect = 2e-13
Identities = 59/244 (24%), Positives = 114/244 (46%), Gaps = 27/244 (11%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLS 556
A+K V+ ++ ES + + EI +LK +E+ V+KL D + + L+L++E +L
Sbjct: 78 AIKIVNREKLSESVLMKVEREIAILKLIEHPH-VLKLHDVYENKKYLYLVLEHVSGGELF 136
Query: 557 QVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGI 615
L ++ ++ + R F++++ + H I H DLKP N + K ++I DFG+
Sbjct: 137 DYLVKKGRLT--PKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGM 194
Query: 616 ANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQ 675
A+ ++ + G+P+Y PE + + G+ +D+WSCG IL+
Sbjct: 195 ASLQVGDSL---LETSCGSPHYACPEVIKGEKYD-----------GRRADMWSCGVILFA 240
Query: 676 MVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVT 735
++ G P+ L + +P+ IP +R +E P R++
Sbjct: 241 LLVGALPFDDDNLRQLLEKVKRGVFHMPH--------FIPPDCQSLLRGMIEVEPEKRLS 292
Query: 736 IDQL 739
++Q+
Sbjct: 293 LEQI 296
>Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2092
Score = 75.9 bits (185), Expect = 2e-13
Identities = 52/183 (28%), Positives = 84/183 (45%), Gaps = 31/183 (16%)
Query: 566 PFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDFGIAN-AVPDHT 623
P + R +F E + ++ +H+ IVH DLKP N + G +K+ DFG++ + T
Sbjct: 133 PLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMT 192
Query: 624 VNIYR-----------DNQI-GTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGC 671
N+Y D Q+ GTP Y+APE ++ + GKP D W+ G
Sbjct: 193 TNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGY------------GKPVDWWAMGI 240
Query: 672 ILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPI 731
ILY+ + G P+ +++ ++ +PEKD P D I L +NP+
Sbjct: 241 ILYEFLVGCVPFFGDTPEELFGQVISDEIN--WPEKDE---APPPDAQDLITLLLRQNPL 295
Query: 732 SRV 734
R+
Sbjct: 296 ERL 298
>Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 505
Score = 75.9 bits (185), Expect = 2e-13
Identities = 64/228 (28%), Positives = 109/228 (47%), Gaps = 29/228 (12%)
Query: 518 EIELLKKLENKQRVVKLIDY--HMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYH 575
EI +LKKL++ VVKLI+ + L+L+ + V+ PF E R +
Sbjct: 199 EIAILKKLDHVN-VVKLIEVLDDPAEDNLYLVFDLLRK--GPVMEVPCDKPFSEEQARLY 255
Query: 576 FQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYRDNQIGT 634
+++I ++ +H IVH D+KP+N + G +KI DFG++N + + + GT
Sbjct: 256 LRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQL--SSTAGT 313
Query: 635 PNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYA 694
P +MAPE + + + GK DVW+ G LY VYGK P+ +
Sbjct: 314 PAFMAPEAI---------SDSGQSFSGKALDVWATGVTLYCFVYGKCPF-----IDDFIL 359
Query: 695 IMNPDVK---IPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQL 739
++ +K + +PE+ I + D I L++NP +R+ + +
Sbjct: 360 ALHRKIKNEPVVFPEEPE----ISEELKDLILKMLDKNPETRIGVPDI 403
>CE21086 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 637
Score = 75.9 bits (185), Expect = 2e-13
Identities = 52/194 (26%), Positives = 92/194 (46%), Gaps = 17/194 (8%)
Query: 494 HKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRV--VKLIDYHMG-QGVLFLLMEC 550
+K++A+K +S DE ++ K E + K+L + + + L + + +L
Sbjct: 42 NKMFAMKEISIVGKDECFMESIKRECSIQKRLSKSRHLNMIHLFEIRTNPENYQLILSYA 101
Query: 551 GEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLK 609
DL + + Q + D E RY F+++I ++ +H+ + H D+KP N + K G+LK
Sbjct: 102 DGGDLFEKINQHGGLGSD-EAHRY-FKQLIDGLRFIHEEGVTHRDIKPENLLLTKSGILK 159
Query: 610 IIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
I DFG A + + G+P Y+APE L +++ G D+WS
Sbjct: 160 IADFGFATMHRFNGAEQMLNAYCGSPPYIAPEVLTGIDYR-----------GPAVDIWSA 208
Query: 670 GCILYQMVYGKPPY 683
G +L M+ G P+
Sbjct: 209 GVVLIAMIAGAVPW 222
Score = 67.0 bits (162), Expect = 1e-10
Identities = 62/254 (24%), Positives = 107/254 (41%), Gaps = 30/254 (11%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKL-----ENKQRVVKLIDYHMGQGVLFLLMECGE 552
A+K V+ ++ + E ++ ++L EN +++K+I+ ++ + G
Sbjct: 371 AVKEVAVSGKSRKNLTAVQKEYKIHRRLSKIGHENVIQMMKMIETPKFYSLVMEYADGG- 429
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFV-------K 605
DL L ++ K F + +F+++IK +K +H+ IVH D+K N + V
Sbjct: 430 -DLFDELKEQEK--FSRKDAHSYFKQLIKGLKFIHEQGIVHRDIKLENLLLVYSESEDDP 486
Query: 606 GMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSD 665
G LKI DFG+A I G+ Y APE ++ G P D
Sbjct: 487 GTLKITDFGLATKYRKDGEEIMLSEDCGSKPYAAPEVCTGNDYR-----------GPPVD 535
Query: 666 VWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSC 725
+WS G +L M+ G+ + N A + + EK + VI +R
Sbjct: 536 IWSAGVVLMTMLVGEHSWKV--ANKEKDAAYSNWINAK-DEKANLWNVISGPTTALLRKL 592
Query: 726 LERNPISRVTIDQL 739
L NP R T+ ++
Sbjct: 593 LHANPEKRATMAKI 606
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 75.9 bits (185), Expect = 2e-13
Identities = 63/222 (28%), Positives = 102/222 (45%), Gaps = 30/222 (13%)
Query: 470 TAYEKVELLXXXXXXXXXXXXXX-DHKVYALKRVSFDEFDESSIDGFKGEIELLKKLENK 528
T YEK+E + K+ ALK+V FD + S+ EI +L++L N
Sbjct: 112 TTYEKLEKIGQGTYSNVYKAKDLLSGKIVALKKVRFDNLEAESVKFMAREILVLRRL-NH 170
Query: 529 QRVVKLIDYHMGQGV--------LFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMI 580
V+KL QG+ L+L+ E EHDLS + + + FD V+ ++++
Sbjct: 171 PNVIKL------QGLVTSRVSCSLYLVFEYMEHDLSGLAATQG-LKFDLPQVKCFMKQLL 223
Query: 581 KCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMA 639
++ H ++H D+K +N + G+LKI DFG+A D +++ T Y
Sbjct: 224 SGLEHCHSRGVLHRDIKGSNLLIDNDGILKIADFGLATFY-DPKQKQTMTSRVVTLWYRP 282
Query: 640 PETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKP 681
PE L+ G D+WS GCI+ +++ GKP
Sbjct: 283 PELLLGAT-----------SYGTGVDLWSAGCIMAELLAGKP 313
>At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 531
Score = 75.9 bits (185), Expect = 2e-13
Identities = 67/259 (25%), Positives = 114/259 (43%), Gaps = 54/259 (20%)
Query: 499 LKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQ 557
LKR + D+ + K EI++++ L + +V++ + + + L+ME C +L
Sbjct: 112 LKRKLISKQDKEDV---KREIQIMQYLSGQPNIVEIKGAYEDRQSIHLVMELCAGGEL-- 166
Query: 558 VLTQRSKIPFDTEFVRYHFQE---------MIKCVKVVHDADIVHSDLKPANFVFVK--- 605
FD + H+ E ++ V++ H +VH DLKP NF+
Sbjct: 167 ---------FDRIIAQGHYSERAAAGIIRSIVNVVQICHFMGVVHRDLKPENFLLSSKEE 217
Query: 606 -GMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPS 664
MLK DFG++ + + V YRD +G+ Y+APE L + GK
Sbjct: 218 NAMLKATDFGLSVFIEEGKV--YRDI-VGSAYYVAPEVL-------------RRSYGKEI 261
Query: 665 DVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKI---PYPEKDSFGTVIPRTVIDT 721
D+WS G ILY ++ G PP+ ++ ++ P+P I + D
Sbjct: 262 DIWSAGVILYILLSGVPPFWAENEKGIFDEVIKGEIDFVSEPWPS-------ISESAKDL 314
Query: 722 IRSCLERNPISRVTIDQLL 740
+R L ++P R+T Q+L
Sbjct: 315 VRKMLTKDPKRRITAAQVL 333
>7293496 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 805
Score = 75.9 bits (185), Expect = 2e-13
Identities = 65/251 (25%), Positives = 114/251 (44%), Gaps = 30/251 (11%)
Query: 493 DHKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGE 552
D KV A+K +S + + E ++ +L++ V+++I+ + LF++ E
Sbjct: 26 DSKVVAIKVISKRGRATKELKNLRRECDIQARLKHPH-VIEMIESFESKTDLFVVTEFAL 84
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKII 611
DL + L+ + E R ++ + +H I+H DLKP N + K M K+
Sbjct: 85 MDLHRYLSYNGAM--GEEPARRVTGHLVSALYYLHSNRILHRDLKPQNVLLDKNMHAKLC 142
Query: 612 DFGIAN--AVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
DFG+A + H + + GTP YMAPE L + + +D+WS
Sbjct: 143 DFGLARNMTLGTHVLTSIK----GTPLYMAPELLAEQPYDHH------------ADMWSL 186
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
GCI Y+ + G+PP+ + + I + DVK P + + ++ LE++
Sbjct: 187 GCIAYESMAGQPPFCASSILHLVKMIKHEDVKWP--------STLTSECRSFLQGLLEKD 238
Query: 730 PISRVTIDQLL 740
P R++ QLL
Sbjct: 239 PGLRISWTQLL 249
>Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 489
Score = 75.5 bits (184), Expect = 3e-13
Identities = 68/231 (29%), Positives = 101/231 (43%), Gaps = 32/231 (13%)
Query: 523 KKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYH------- 575
+KLE + R+ +L+ + + + E G H L L ++ D Y+
Sbjct: 55 QKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASH 114
Query: 576 -FQEMIKCVKVVHDADIVHSDLKPANFVFVKGM----LKIIDFGIANAVPDHTVNIYRDN 630
Q++++ V H +VH DLKP N + + +K+ DFG+A V +
Sbjct: 115 CIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWF--G 172
Query: 631 QIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNN 690
GTP Y++PE L K GKP D+W+CG ILY ++ G PP+ + +
Sbjct: 173 FAGTPGYLSPEVL------------RKDPYGKPVDLWACGVILYILLVGYPPFWD-EDQH 219
Query: 691 RLY-AIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
RLY I P PE D TV P D I L NP R+T + L
Sbjct: 220 RLYQQIKAGAYDFPSPEWD---TVTPEAK-DLINKMLTINPSKRITAAEAL 266
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 75.5 bits (184), Expect = 3e-13
Identities = 61/255 (23%), Positives = 114/255 (43%), Gaps = 29/255 (11%)
Query: 495 KVYALKRVSFDEF-DESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGE 552
+V A+K + D+ DE + + EIE++ L N ++ + + + + ++ME +
Sbjct: 79 RVVAIKSIRKDKIKDEQDMVHIRREIEIMSSL-NHPHIISIYEVFENKDKIVIIMEYASK 137
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKII 611
+L +++R ++ R+ F++++ V H +VH DLK N + +KI
Sbjct: 138 GELYDYISERRRL--SERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIA 195
Query: 612 DFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGC 671
DFG++N + + + G+P Y +PE + + G D W+ G
Sbjct: 196 DFGLSNL---YQKDKFLQTFCGSPLYASPEIVNGRPYR-----------GPEVDSWALGV 241
Query: 672 ILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPI 731
+LY +VYG P+ F N + I + + + P D+ G IR L NP
Sbjct: 242 LLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPSDARG---------LIRWMLMVNPD 292
Query: 732 SRVTIDQLLSGALIN 746
R TI+ + + +N
Sbjct: 293 RRATIEDIANHWWVN 307
>At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 347
Score = 75.5 bits (184), Expect = 3e-13
Identities = 64/257 (24%), Positives = 118/257 (45%), Gaps = 34/257 (13%)
Query: 495 KVYALKRVSFDEF-DESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGE 552
K +A K + + DE + K EI ++K+L + +V+ + + + + ++ME CG
Sbjct: 52 KTFACKTILKTKLKDEECEEDVKREIRIMKQLSGEPNIVEFKNAYEDKDSVHIVMEYCGG 111
Query: 553 HDLSQVLTQRSKI--PFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKG---- 606
+L + + + + + ++ VK H ++H DLKP NF+
Sbjct: 112 GELYDKILALYDVGKSYSEKEAAGIIRSIVNVVKNCHYMGVMHRDLKPENFLLTSNDDNA 171
Query: 607 MLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDV 666
+K+IDFG + + + V Y+D G+ Y+APE L + GK +D+
Sbjct: 172 TVKVIDFGCSVFIEEGKV--YQD-LAGSDYYIAPEVL-------------QGNYGKEADI 215
Query: 667 WSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDV---KIPYPEKDSFGTVIPRTVIDTIR 723
WS G ILY ++ GK P+ I + ++ + P+P +DS I ++
Sbjct: 216 WSAGIILYILLCGKSPFVKEPEGQMFNEIKSLEIDYSEEPWPLRDS-------RAIHLVK 268
Query: 724 SCLERNPISRVTIDQLL 740
L+RNP R++ ++L
Sbjct: 269 RMLDRNPKERISAAEVL 285
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 75.5 bits (184), Expect = 3e-13
Identities = 69/253 (27%), Positives = 115/253 (45%), Gaps = 34/253 (13%)
Query: 497 YALKRVSFDEF-DESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHD 554
YA K +S + I+ + E+ +L+ L + +V+ + + L L+ME C +
Sbjct: 111 YACKSISKRKLIRRKDIEDVRREVMILQHLTGQPNIVEFRGAYEDKDNLHLVMELCSGGE 170
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKI 610
L + ++ + + F++++ V V H +VH DLKP NF+ V +K
Sbjct: 171 LFDRIIKKGS--YSEKEAANIFRQIVNVVHVCHFMGVVHRDLKPENFLLVSNEEDSPIKA 228
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG++ + + +YRD +G+ Y+APE L RN GK DVWS G
Sbjct: 229 TDFGLSVFIEEG--KVYRD-IVGSAYYVAPEVL-----HRN--------YGKEIDVWSAG 272
Query: 671 CILYQMVYGKPPYGTFQGNNRLYAIMNPDVKI---PYPEKDSFGTVIPRTVIDTIRSCLE 727
+LY ++ G PP+ AI+ + + P+P I + D IR L
Sbjct: 273 VMLYILLSGVPPFWGETEKTIFEAILEGKLDLETSPWP-------TISESAKDLIRKMLI 325
Query: 728 RNPISRVTIDQLL 740
R+P R+T + L
Sbjct: 326 RDPKKRITAAEAL 338
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 75.5 bits (184), Expect = 3e-13
Identities = 66/249 (26%), Positives = 114/249 (45%), Gaps = 34/249 (13%)
Query: 516 KGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTEFVRY 574
K EI +L+++ + +V L + + ++ +ME G +L + + ++P +T R
Sbjct: 120 KREISILRRVRHPY-IVHLFEVMATKSKIYFVMEYVGGGELFNTVA-KGRLPEET--ARR 175
Query: 575 HFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYRDNQIG 633
+FQ++I V H + H DLKP N + KG LK+ DFG++ + G
Sbjct: 176 YFQQLISSVSFCHGRGVYHRDLKPENLLLDNKGNLKVSDFGLSAVAEQLRQDGLCHTFCG 235
Query: 634 TPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLY 693
TP Y+APE L TR + AK +DVWSCG IL+ ++ G P+
Sbjct: 236 TPAYIAPEVL-----TRKGYDAAK------ADVWSCGVILFVLMAGHIPF---------- 274
Query: 694 AIMNPDVKIPYPEKDSFGTVIPR----TVIDTIRSCLERNPISRVTIDQLLSGALINP-V 748
+ ++ + Y + PR ++ + L+ NP +R+TI +++
Sbjct: 275 --YDKNIMVMYKKIYKGEFRCPRWFSSDLVRLLTRLLDTNPDTRITIPEIMKNRWFKKGF 332
Query: 749 TVTKFFIHD 757
KF+I D
Sbjct: 333 KHVKFYIED 341
>YAL017w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1356
Score = 75.1 bits (183), Expect = 4e-13
Identities = 60/229 (26%), Positives = 105/229 (45%), Gaps = 36/229 (15%)
Query: 518 EIELLKKLENK--QRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYH 575
EI+++ L K + +++L+D+ ++ E H + + I F T +
Sbjct: 1149 EIQIMATLNKKPHENILRLLDFFEDDDYYYI--ETPVHGETGCIDLFDLIEFKTNMTEFE 1206
Query: 576 ----FQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYRDN 630
F++++ +K +HD IVH D+K N + KG +KIIDFG A V +++
Sbjct: 1207 AKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYVKSGPFDVF--- 1263
Query: 631 QIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNN 690
+GT +Y APE L + G+P D+W+ G +LY +V+ + P+
Sbjct: 1264 -VGTIDYAAPEVLGGNPYE-----------GQPQDIWAIGILLYTVVFKENPF------Y 1305
Query: 691 RLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQL 739
+ I+ D+K E+ + I+ I+S L R R TID +
Sbjct: 1306 NIDEILEGDLKFNNAEE------VSEDCIELIKSILNRCVPKRPTIDDI 1348
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 75.1 bits (183), Expect = 4e-13
Identities = 73/255 (28%), Positives = 119/255 (46%), Gaps = 36/255 (14%)
Query: 495 KVYALKRVSFDE-FDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMEC--G 551
K++ALK + F +SS++ EI +LKK+++ + +V L D + +L+M+ G
Sbjct: 47 KLFALKCIKKSPAFRDSSLEN---EIAVLKKIKH-ENIVTLEDIYESTTHYYLVMQLVSG 102
Query: 552 EHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFV----KGM 607
++L + D V Q+++ VK +H+ IVH DLKP N +++
Sbjct: 103 GELFDRILERGVYTEKDASLV---IQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSK 159
Query: 608 LKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVW 667
+ I DFG++ N GTP Y+APE L A+ K D W
Sbjct: 160 IMITDFGLSKM----EQNGIMSTACGTPGYVAPEVL------------AQKPYSKAVDCW 203
Query: 668 SCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDS-FGTVIPRTVIDTIRSCL 726
S G I Y ++ G PP+ + ++L+ +K Y E +S F I + D I L
Sbjct: 204 SIGVITYILLCGYPPFYE-ETESKLF----EKIKEGYYEFESPFWDDISESAKDFICHLL 258
Query: 727 ERNPISRVTIDQLLS 741
E++P R T ++ LS
Sbjct: 259 EKDPNERYTCEKALS 273
>Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 499
Score = 75.1 bits (183), Expect = 4e-13
Identities = 70/236 (29%), Positives = 102/236 (42%), Gaps = 42/236 (17%)
Query: 523 KKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYH------- 575
+KLE + R+ +L+ + + + E G H L L ++ D Y+
Sbjct: 56 QKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASH 115
Query: 576 -FQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKIIDFGIANAVPDHTVNIYRDN 630
Q++++ V H IVH DLKP N + +K+ DFG+A + + D
Sbjct: 116 CIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLA-------IEVQGDQ 168
Query: 631 QI-----GTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGT 685
Q GTP Y++PE L K GKP D+W+CG ILY ++ G PP+
Sbjct: 169 QAWFGFAGTPGYLSPEVL------------RKDPYGKPVDMWACGVILYILLVGYPPFWD 216
Query: 686 FQGNNRLY-AIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
+ +RLY I P PE D TV P D I L NP R+T + L
Sbjct: 217 -EDQHRLYQQIKAGAYDFPSPEWD---TVTPEAK-DLINKMLTINPAKRITASEAL 267
>At5g67080 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 344
Score = 75.1 bits (183), Expect = 4e-13
Identities = 62/215 (28%), Positives = 97/215 (44%), Gaps = 35/215 (16%)
Query: 572 VRYHFQEMIKCVKVVHDADIVHSDLKPANFV-FVKGMLKIIDFGIANAVPDHTVNIYRDN 630
VR H +++ ++ +H H DLK N + F G +KI DFG+A + D T Y
Sbjct: 110 VRRHTGSVLRGLRHIHANGFAHCDLKLGNILLFGDGAVKIADFGLAKRIGDLTALNYGVQ 169
Query: 631 QIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNN 690
GTP YMAPE++ ND E G DVW+ GC++ +M GK + +G+N
Sbjct: 170 IRGTPLYMAPESV-------NDNE-----YGSEGDVWALGCVVVEMFSGKTAWSLKEGSN 217
Query: 691 RLYAIMNPDVKIPYPEKDSFGTVIPRTVI----DTIRSCLERNPISRVTIDQLLSGALIN 746
+ ++ V P +IP + D + C ++P R T + LL N
Sbjct: 218 FMSLLLRIGVGDEVP-------MIPEELSEQGRDFLSKCFVKDPKKRWTAEMLL-----N 265
Query: 747 PVTVTKFFIHDLIKNAVNYGCDQKHVNNERVEELS 781
VT HD++ ++ V N + E++S
Sbjct: 266 HPFVTVDVDHDVLVK------EEDFVVNMKTEDVS 294
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 75.1 bits (183), Expect = 4e-13
Identities = 76/270 (28%), Positives = 117/270 (43%), Gaps = 30/270 (11%)
Query: 512 IDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEF 571
++ K EI ++K L +V+L + + +F +ME + ++ + SK +
Sbjct: 55 MEQIKREISIMK-LVRHPNIVELKEVMATKTKIFFVMEFVKG--GELFCKISKGKLHEDA 111
Query: 572 VRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDFGIANAVPDHTVNI-YRD 629
R +FQ++I V H + H DLKP N + + G LKI DFG++ A+P+ +
Sbjct: 112 ARRYFQQLISAVDYCHSRGVSHRDLKPENLLLDENGDLKISDFGLS-ALPEQILQDGLLH 170
Query: 630 NQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGN 689
Q GTP Y+APE L + DG +A D+WSCG +LY ++ G P+
Sbjct: 171 TQCGTPAYVAPEVLKKKGY---DGAKA--------DIWSCGVVLYVLLAGCLPFQDENLM 219
Query: 690 NRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALINPVT 749
N I D + P F R I L +P R++I A++
Sbjct: 220 NMYRKIFRADFEFP----PWFSPEARR----LISKLLVVDPDRRISIP-----AIMRTPW 266
Query: 750 VTKFFIHDLIKNAVNYGCDQKHVNNERVEE 779
+ K F L C Q NNE EE
Sbjct: 267 LRKNFTPPLAFKIDEPICSQSSKNNEEEEE 296
>At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 530
Score = 75.1 bits (183), Expect = 4e-13
Identities = 69/265 (26%), Positives = 116/265 (43%), Gaps = 54/265 (20%)
Query: 495 KVYALKRVSFDEFDES-SIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGE 552
+++A K + + S I+ K E+E+++++ +V L + + + L+ME C
Sbjct: 78 EIFACKSILKKKLKTSIDIEDVKREVEIMRQMPEHPNIVTLKETYEDDKAVHLVMELCEG 137
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQE---------MIKCVKVVHDADIVHSDLKPANFVF 603
+L FD R H+ E +I+ V++ H ++H DLKP NF+F
Sbjct: 138 GEL-----------FDRIVARGHYTERAAASVIKTIIEVVQMCHKHGVMHRDLKPENFLF 186
Query: 604 VK----GMLKIIDFGIANAV-PDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKW 658
LK IDFG++ P N +G+P YMAPE L +
Sbjct: 187 ANKKETASLKAIDFGLSVFFKPGERFN----EIVGSPYYMAPEVL-------------RR 229
Query: 659 KVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDV---KIPYPEKDSFGTVIP 715
G+ D+WS G ILY ++ G PP+ + AI+ + + P+P+ +
Sbjct: 230 SYGQEIDIWSAGVILYILLCGVPPFWAETEHGVAKAILKSVIDFKRDPWPK-------VS 282
Query: 716 RTVIDTIRSCLERNPISRVTIDQLL 740
D I+ L +P R+T Q+L
Sbjct: 283 DNAKDLIKKMLHPDPRRRLTAQQVL 307
>YOL045w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1101
Score = 74.7 bits (182), Expect = 5e-13
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 38/230 (16%)
Query: 518 EIELLKKLE--NKQRVVKLIDYHMGQGVLFLLM----ECGEHDLSQVLT-QRSKIPFDTE 570
EI+++ L +++ ++KL+D+ ++ E G DL V+ ++ + + +
Sbjct: 894 EIQIMATLNKNSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAK 953
Query: 571 FVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDFGIANAVPDHTVNIYRD 629
V F++++ +K +HD IVH D+K N + G +K+IDFG A + +++
Sbjct: 954 LV---FKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPFDVF-- 1008
Query: 630 NQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGN 689
+GT +Y APE L ++ GKP D+W+ G +LY ++Y + PY
Sbjct: 1009 --VGTMDYAAPEVLGGSSYK-----------GKPQDIWALGVLLYTIIYKENPY------ 1049
Query: 690 NRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQL 739
+ I+ +++ E + I I+ L R R TID++
Sbjct: 1050 YNIDEILEGELRFDKSEH------VSEECISLIKRILTREVDKRPTIDEI 1093
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 74.7 bits (182), Expect = 5e-13
Identities = 61/235 (25%), Positives = 108/235 (45%), Gaps = 28/235 (11%)
Query: 514 GFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DLSQVLTQRSKIPFDTEFV 572
G + EI ++K + + V+ L + + L+L++E + +L L + K+P + E +
Sbjct: 160 GIEREIVIMKLISHTN-VMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLP-EREAI 217
Query: 573 RYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKG--MLKIIDFGIANAVPDHTVNIYRDN 630
Y F+++++ V H +I H DLKP N + K +KI DFG+A N
Sbjct: 218 HY-FKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAAL---ELPNKLLKT 273
Query: 631 QIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNN 690
G+P+Y +PE ++ + G PSDVWSCG +L+ ++ G P+
Sbjct: 274 SCGSPHYASPEIVMGRPYH-----------GGPSDVWSCGIVLFALLTGHLPFNDDNIKK 322
Query: 691 RLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALI 745
L + + ++P + + D I L +P R+T ++L LI
Sbjct: 323 LLLKVQSGKYQMP--------SNLSSEARDLISKILVIDPEKRITTQEILKHPLI 369
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 74.7 bits (182), Expect = 5e-13
Identities = 60/253 (23%), Positives = 115/253 (44%), Gaps = 45/253 (17%)
Query: 518 EIELLKKLENKQRVVKLIDY-----HMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFV 572
EI+LL+ + + ++ ++D + ++++ E E DL +V+ + P +
Sbjct: 85 EIKLLRHFRH-ENIISILDILPPPSYQELEDVYIVQELMETDLYRVIRSQ---PLSDDHC 140
Query: 573 RYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVNI-YRDN 630
+Y ++++ +K +H A +VH DLKP+N + LK+ DFG+A + N +
Sbjct: 141 QYFTYQILRALKAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGFMTE 200
Query: 631 QIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNN 690
+ T Y APE +++ + K D+WS GCIL +M+ +P + ++
Sbjct: 201 YVATRWYRAPEIMLSFR-----------EYSKAIDLWSTGCILAEMLSARPLFPGKDYHS 249
Query: 691 RLYAIMN----PDV----------------KIPYPEKDSFGTVIPRT---VIDTIRSCLE 727
++ I+N P + +P+ K SF + P+ ID + L
Sbjct: 250 QITLILNILGTPTMDDFSRIKSARARKYIKSLPFTPKVSFKALFPQASPDAIDLLEKLLT 309
Query: 728 RNPISRVTIDQLL 740
NP R+T ++ L
Sbjct: 310 FNPDKRITAEEAL 322
>Hs4506089 [T] KOG0660 Mitogen-activated protein kinase
Length = 557
Score = 74.7 bits (182), Expect = 5e-13
Identities = 76/321 (23%), Positives = 141/321 (43%), Gaps = 62/321 (19%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQG-----------VLFL 546
A+K+++ D S+ EI+++++L++ +VK+ + +G V ++
Sbjct: 47 AVKKIALS--DARSMKHALREIKIIRRLDH-DNIVKVYEVLGPKGTDLQGELFKFSVAYI 103
Query: 547 LMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKG 606
+ E E DL+++L Q + E + ++++ +K +H A+++H DLKPAN +F+
Sbjct: 104 VQEYMETDLARLLEQGT---LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPAN-IFIST 159
Query: 607 ---MLKIIDFGIANAVPDH-TVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGK 662
+LKI DFG+A V H + Y + T Y +P L++ N K
Sbjct: 160 EDLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKWYRSPRLLLSPN-----------NYTK 208
Query: 663 PSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTV---- 718
D+W+ GCIL +M+ G+ + ++ I+ I +KD V+P V
Sbjct: 209 AIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIREEDKDELLRVMPSFVSSTW 268
Query: 719 -----------------IDTIRSCLERNPISRVTIDQLLSGALINPVTVTK--------F 753
ID + L NP+ R+T + L ++P + + F
Sbjct: 269 EVKRPLRKLLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYMSPYSCPEDEPTSQHPF 328
Query: 754 FIHDLIKNAVNYGCDQKHVNN 774
I D I + V +Q ++N
Sbjct: 329 RIEDEIDDIVLMAANQSQLSN 349
>Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 664
Score = 74.7 bits (182), Expect = 5e-13
Identities = 65/235 (27%), Positives = 98/235 (41%), Gaps = 40/235 (17%)
Query: 523 KKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYH------- 575
+KLE + R+ +L+ + + + E G H L L ++ D Y+
Sbjct: 56 QKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASH 115
Query: 576 -FQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKIIDFGIANAVPDHTVNIYRDN 630
Q++++ V H +VH DLKP N + +K+ DFG+A + + D
Sbjct: 116 CIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLA-------IEVQGDQ 168
Query: 631 QI-----GTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGT 685
Q GTP Y++PE L K GKP D+W+CG ILY ++ G PP+
Sbjct: 169 QAWFGFAGTPGYLSPEVL------------RKEAYGKPVDIWACGVILYILLVGYPPFWD 216
Query: 686 FQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
+ I P PE D TV P + I L NP R+T + L
Sbjct: 217 EDQHKLYQQIKAGAYDFPSPEWD---TVTPEAK-NLINQMLTINPAKRITAHEAL 267
>Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 302
Score = 74.7 bits (182), Expect = 5e-13
Identities = 63/215 (29%), Positives = 106/215 (49%), Gaps = 26/215 (12%)
Query: 498 ALKRVS-FDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DL 555
ALK+V FD D + EI+LLK+L N V+K + L +++E + DL
Sbjct: 61 ALKKVQIFDLMDAKARADCIKEIDLLKQL-NHPNVIKYYASFIEDNELNIVLELADAGDL 119
Query: 556 SQVLT----QRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLKI 610
S+++ Q+ IP T V +F ++ ++ +H ++H D+KPAN F+ G++K+
Sbjct: 120 SRMIKHFKKQKRLIPERT--VWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKL 177
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
D G+ T + + +GTP YM+PE + +G K SD+WS G
Sbjct: 178 GDLGLGRFFSSKTTAAH--SLVGTPYYMSPERI------HENGYNFK------SDIWSLG 223
Query: 671 CILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYP 705
C+LY+M + P+ + LY++ + YP
Sbjct: 224 CLLYEMAALQSPF--YGDKMNLYSLCKKIEQCDYP 256
>Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1734
Score = 74.7 bits (182), Expect = 5e-13
Identities = 63/208 (30%), Positives = 98/208 (46%), Gaps = 38/208 (18%)
Query: 544 LFLLMECGEH-DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFV 602
L ++ME E D + +L +P D VR +F E + ++ +H+ IVH DLKP N +
Sbjct: 585 LCMVMEYVEGGDCATLLKNIGALPVD--MVRLYFAETVLALEYLHNYGIVHRDLKPDNLL 642
Query: 603 FVK-GMLKIIDFGIAN-AVPDHTVNIYR-----------DNQI-GTPNYMAPETLVAMNF 648
G +K+ DFG++ + T N+Y D Q+ GTP Y+APE ++ +
Sbjct: 643 ITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGY 702
Query: 649 TRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGN--NRLYAIMNPDVKIPYPE 706
GKP D W+ G ILY+ + G P F G+ L+ + D +I +PE
Sbjct: 703 ------------GKPVDWWAMGIILYEFLVGCVP---FFGDTPEELFGQVISD-EIVWPE 746
Query: 707 KDSFGTVIPRTVIDTIRSCLERNPISRV 734
D +P D L +NP+ R+
Sbjct: 747 GDE---ALPPDAQDLTSKLLHQNPLERL 771
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 74.7 bits (182), Expect = 5e-13
Identities = 59/231 (25%), Positives = 109/231 (46%), Gaps = 25/231 (10%)
Query: 512 IDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEF 571
+D K EI +++ +++ +V+L + + ++ ME ++ + +K +
Sbjct: 66 VDQIKREISVMRMVKHPN-IVELHEVMASKSKIYFAMELVRG--GELFAKVAKGRLREDV 122
Query: 572 VRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYRDN 630
R +FQ++I V H + H DLKP N + +G LK+ DFG++ +
Sbjct: 123 ARVYFQQLISAVDFCHSRGVYHRDLKPENLLLDEEGNLKVTDFGLSAFTEHLKQDGLLHT 182
Query: 631 QIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNN 690
GTP Y+APE ++ + DG +A D+WSCG IL+ ++ G P+ N
Sbjct: 183 TCGTPAYVAPEVILKKGY---DGAKA--------DLWSCGVILFVLLAGYLPFQDDNLVN 231
Query: 691 RLYAIMNPDVKIP-YPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
I D K P + D+ R ++ + L+ NP +R+TI++++
Sbjct: 232 MYRKIYRGDFKCPGWLSSDA------RRLVTKL---LDPNPNTRITIEKVM 273
>At4g08480 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 773
Score = 74.7 bits (182), Expect = 5e-13
Identities = 86/340 (25%), Positives = 146/340 (42%), Gaps = 48/340 (14%)
Query: 412 KVEIVEPPKSTVEVIPLKSEGCDVSSKLNKGDNYLNYNGSFDTKKRTSYAVPTITVNGTA 471
KVE E +++ E C ++ N+GD S T TS + T+
Sbjct: 450 KVEKEETGDMFIQLEDTTDEACSFTT--NEGD-------SSSTVSNTSPICVSGGSINTS 500
Query: 472 YEKVELLXXXXXXXXXXXXXXDHKVYALKRVSFDEFDESS-----IDGFKGEIELLKKLE 526
++K +LL D +A+K VS D+ S I +GEI LL +LE
Sbjct: 501 WQKGQLLRQGSFGSVYEAISEDGDFFAVKEVSL--LDQGSQAQECIQQLEGEIALLSQLE 558
Query: 527 NKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVV 586
+ Q +++ L++ +E L +R +I + + ++++ +K +
Sbjct: 559 H-QNILRYRGTDKDGSNLYIFLELVTQGSLLELYRRYQIR--DSLISLYTKQILDGLKYL 615
Query: 587 HDADIVHSDLKPANF-VFVKGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVA 645
H +H D+K A V G +K+ DFG+A + + ++ T +MAPE +
Sbjct: 616 HHKGFIHRDIKCATILVDANGTVKLADFGLAKVSKLNDIKSRKE----TLFWMAPEVI-- 669
Query: 646 MNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYP 705
N NDG ++ P+D+WS GC + +M G+ PY + L+ I + P
Sbjct: 670 -NRKDNDGYRS------PADIWSLGCTVLEMCTGQIPYSDLEPVEALFRIRRGTL----P 718
Query: 706 EKDSFGTVIPRTV-IDT---IRSCLERNPISRVTIDQLLS 741
E +P T+ +D I CL+ NP R T +LL+
Sbjct: 719 E-------VPDTLSLDARHFILKCLKLNPEERPTATELLN 751
>At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 836
Score = 74.7 bits (182), Expect = 5e-13
Identities = 69/249 (27%), Positives = 121/249 (47%), Gaps = 26/249 (10%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEH 553
++ A+K +S E +E + +GEIE+L++ N VV+ + + G+ L+++ME CG
Sbjct: 273 EIVAVKVISLTEGEEG-YEEIRGEIEMLQQC-NHPNVVRYLGSYQGEDYLWIVMEYCGGG 330
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIID 612
++ ++ + + + + Y +E +K + +H VH D+K N + + G +K+ D
Sbjct: 331 SVADLMNVTEEALEEYQ-IAYICREALKGLAYLHSIYKVHRDIKGGNILLTEQGEVKLGD 389
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG+A A T++ R+ IGTP++MAPE + R DG+ DVW+ G
Sbjct: 390 FGVA-AQLTRTMS-KRNTFIGTPHWMAPEVI---QENRYDGK---------VDVWALGVS 435
Query: 673 LYQMVYGKPPYGTFQGNNRLYAI-MNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPI 731
+M G PP + L+ I + P + EK S D + CL + P
Sbjct: 436 AIEMAEGLPPRSSVHPMRVLFMISIEPAPMLEDKEKWSL------VFHDFVAKCLTKEPR 489
Query: 732 SRVTIDQLL 740
R T ++L
Sbjct: 490 LRPTAAEML 498
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 74.7 bits (182), Expect = 5e-13
Identities = 71/271 (26%), Positives = 120/271 (44%), Gaps = 47/271 (17%)
Query: 509 ESSIDGFKG--EIELLKKLENKQRVVKLIDYHMGQGV-----LFLLMECGEHDLSQVLTQ 561
E+ ID + E++LL+ L + + VV L D M ++L+ E + DL Q++
Sbjct: 68 ENRIDALRTLRELKLLRHLRH-ENVVALKDVMMANHKRSFKDVYLVYELMDTDLHQII-- 124
Query: 562 RSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLKIIDFGIANAVP 620
+S + +Y ++++ +K +H A+I+H DLKP N V LKI DFG+A
Sbjct: 125 KSSQVLSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLART-- 182
Query: 621 DHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGK 680
+T + + T Y APE L+ + G DVWS GCI +++ K
Sbjct: 183 SNTKGQFMTEYVVTRWYRAPELLLCCD-----------NYGTSIDVWSVGCIFAELLGRK 231
Query: 681 PPYGTFQGNNRLYAIM---------------NPDVK-----IPYPEKDSFGTVIPRT--- 717
P + + N++ I+ NP K +PY SF + P
Sbjct: 232 PVFPGTECLNQIKLIINILGSQREEDLEFIDNPKAKRYIESLPYSPGISFSRLYPGANVL 291
Query: 718 VIDTIRSCLERNPISRVTIDQLLSGALINPV 748
ID ++ L +P R+++ + L + P+
Sbjct: 292 AIDLLQKMLVLDPSKRISVTEALQHPYMAPL 322
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 74.7 bits (182), Expect = 5e-13
Identities = 82/323 (25%), Positives = 135/323 (41%), Gaps = 71/323 (21%)
Query: 457 RTSYAVPTITVNGTAYEKVELLXXXXXXXXXXXXXXDHKVYALKRVSFDEFDESSIDGFK 516
R +Y V +VN EKV + H VY E+ ID +
Sbjct: 40 RGAYGVVCSSVNSDTNEKVAIKKI-------------HNVY-----------ENRIDALR 75
Query: 517 G--EIELLKKLENKQRVVKLID-----YHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDT 569
E++LL+ L + + V+ L D + M ++L+ E + DL Q++ +S
Sbjct: 76 TLRELKLLRHLRH-ENVIALKDVMMPIHKMSFKDVYLVYELMDTDLHQII--KSSQVLSN 132
Query: 570 EFVRYHFQEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLKIIDFGIANAVPDHTVNIYR 628
+ +Y ++++ +K +H A+I+H DLKP N V LKI DFG+A A +T +
Sbjct: 133 DHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARA--SNTKGQFM 190
Query: 629 DNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQG 688
+ T Y APE L+ + G DVWS GCI +++ KP + +
Sbjct: 191 TEYVVTRWYRAPELLLCCD-----------NYGTSIDVWSVGCIFAELLGRKPIFQGTEC 239
Query: 689 NNRLYAIM---------------NPDVK-----IPYPEKDSFGTVIPRT---VIDTIRSC 725
N+L I+ NP K +PY S + P ID ++
Sbjct: 240 LNQLKLIVNILGSQREEDLEFIDNPKAKRYIRSLPYSPGMSLSRLYPGAHVLAIDLLQKM 299
Query: 726 LERNPISRVTIDQLLSGALINPV 748
L +P R+++ + L + P+
Sbjct: 300 LVFDPSKRISVSEALQHPYMAPL 322
>Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase
Length = 292
Score = 74.7 bits (182), Expect = 5e-13
Identities = 63/251 (25%), Positives = 116/251 (46%), Gaps = 25/251 (9%)
Query: 493 DHKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CG 551
D K Y +K+++ + E +LL +L++ V + G G+L+++M C
Sbjct: 28 DGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCE 87
Query: 552 EHDLSQVLT-QRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLK 609
DL + L Q+ ++ + + V + F ++ ++ +H+ I+H DLK N F+ ++K
Sbjct: 88 GGDLYRKLKEQKGQLLPENQVVEW-FVQIAMALQYLHEKHILHRDLKTQNVFLTRTNIIK 146
Query: 610 IIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
+ D GIA + +H IGTP YM+PE + SDVW+
Sbjct: 147 VGDLGIARVLENHCD--MASTLIGTPYYMSPELFSNKPYNYK------------SDVWAL 192
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERN 729
GC +Y+M K + N+ +Y I+ + K+P +D + + IR+ L +
Sbjct: 193 GCCVYEMATLKHAFNAKDMNSLVYRII--EGKLPAMPRD-----YSPELAELIRTMLSKR 245
Query: 730 PISRVTIDQLL 740
P R ++ +L
Sbjct: 246 PEERPSVRSIL 256
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 74.3 bits (181), Expect = 7e-13
Identities = 77/267 (28%), Positives = 120/267 (44%), Gaps = 42/267 (15%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDY-HMGQGVLFLLMECGEH 553
+V ALK++ + DE EI LLK+L++ +V+L D H L+L+ E +
Sbjct: 35 RVVALKKIRLESEDEGVPSTAIREISLLKELKD-DNIVRLYDIVHSDAHKLYLVFEFLDL 93
Query: 554 DLSQVLTQRSKI-PFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKII 611
DL + + K P + V+ ++ K + H I+H DLKP N + K G LK+
Sbjct: 94 DLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLG 153
Query: 612 DFGIANA--VPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
DFG+A A VP + Y ++I T Y APE L+ G+Q V D WS
Sbjct: 154 DFGLARAFGVP---LRAY-THEIVTLWYRAPEVLLG-------GKQYSTGV----DTWSI 198
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAIMN----------------PDVKIPYPE--KDSFG 711
GCI +M KP + ++++ I PD K +P+ +
Sbjct: 199 GCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWRRKDLS 258
Query: 712 TVIPR---TVIDTIRSCLERNPISRVT 735
V+P ID + L +PI+R++
Sbjct: 259 QVVPSLDPRGIDLLDKLLAYDPINRIS 285
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 74.3 bits (181), Expect = 7e-13
Identities = 60/211 (28%), Positives = 99/211 (46%), Gaps = 37/211 (17%)
Query: 493 DHKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQ-------RVVKLIDYHMGQGVLF 545
D KVYALKR+ E EI++LK ++++ VV+ H +G ++
Sbjct: 58 DGKVYALKRILMHTEKEGFPITAIREIKILKSIKHENIIPLSDMTVVRADKKHRRRGSIY 117
Query: 546 LLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK 605
++ +HDLS +L S + F ++ + +++ K +HD I+H DLK AN +
Sbjct: 118 MVTPYMDHDLSGLLENPS-VKFTEPQIKCYMKQLFAGTKYLHDQLILHRDLKAANLLIDN 176
Query: 606 -GMLKIIDFGIANAVPDHTVNIYRDNQIGTPN--------------YMAPETLVAMNFTR 650
G+LKI DFG+A + + + Y + G P Y +PE L+
Sbjct: 177 HGILKIADFGLARVITEES---YANKNPGLPPPNRREYTGCVVTRWYRSPELLL------ 227
Query: 651 NDGEQAKWKVGKPSDVWSCGCILYQMVYGKP 681
GE+ + D+WS GCI+ +M G+P
Sbjct: 228 --GER---RYTTAIDMWSVGCIMAEMYKGRP 253
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 74.3 bits (181), Expect = 7e-13
Identities = 66/254 (25%), Positives = 109/254 (41%), Gaps = 27/254 (10%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH- 553
K A+K + + + SS+ E+ ++K L N +VKL + + L+L+ME
Sbjct: 44 KEVAVKIIDKTQLNSSSLQKLFREVRIMKVL-NHPNIVKLFEVIETEKTLYLVMEYASGG 102
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIID 612
++ L ++ + R F++++ V+ H IVH DLK N + M +KI D
Sbjct: 103 EVFDYLVAHGRMK--EKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIAD 160
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG +N + T D G+P Y APE Q K G DVWS G I
Sbjct: 161 FGFSN---EFTFGNKLDTFCGSPPYAAPELF-----------QGKKYDGPEVDVWSLGVI 206
Query: 673 LYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPIS 732
LY +V G P+ ++ +IP+ ++ + +I NP
Sbjct: 207 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLI--------LNPSK 258
Query: 733 RVTIDQLLSGALIN 746
R T++Q++ +N
Sbjct: 259 RGTLEQIMKDRWMN 272
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 74.3 bits (181), Expect = 7e-13
Identities = 66/254 (25%), Positives = 109/254 (41%), Gaps = 27/254 (10%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH- 553
K A+K + + + SS+ E+ ++K L N +VKL + + L+L+ME
Sbjct: 44 KEVAVKIIDKTQLNSSSLQKLFREVRIMKVL-NHPNIVKLFEVIETEKTLYLVMEYASGG 102
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIID 612
++ L ++ + R F++++ V+ H IVH DLK N + M +KI D
Sbjct: 103 EVFDYLVAHGRMK--EKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIAD 160
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG +N + T D G+P Y APE Q K G DVWS G I
Sbjct: 161 FGFSN---EFTFGNKLDTFCGSPPYAAPELF-----------QGKKYDGPEVDVWSLGVI 206
Query: 673 LYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPIS 732
LY +V G P+ ++ +IP+ ++ + +I NP
Sbjct: 207 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLI--------LNPSK 258
Query: 733 RVTIDQLLSGALIN 746
R T++Q++ +N
Sbjct: 259 RGTLEQIMKDRWMN 272
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 74.3 bits (181), Expect = 7e-13
Identities = 65/251 (25%), Positives = 110/251 (42%), Gaps = 27/251 (10%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DLS 556
A+K + + + +S+ E+ ++K L N +VKL + + L+L+ME ++
Sbjct: 87 AVKIIDKTQLNPTSLQKLFREVRIMKIL-NHPNIVKLFEVIETEKTLYLVMEYASGGEVF 145
Query: 557 QVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGI 615
L ++ + R F++++ V+ H IVH DLK N + M +KI DFG
Sbjct: 146 DYLVAHGRMK--EKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGF 203
Query: 616 ANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQ 675
+N + TV D G+P Y APE Q K G DVWS G ILY
Sbjct: 204 SN---EFTVGNKLDTFCGSPPYAAPELF-----------QGKKYDGPEVDVWSLGVILYT 249
Query: 676 MVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVT 735
+V G P+ ++ +IP+ + + ++ L NPI R +
Sbjct: 250 LVSGSLPFDGQNLKELRERVLRGKYRIPF--------YMSTDCENLLKKLLVLNPIKRGS 301
Query: 736 IDQLLSGALIN 746
++Q++ +N
Sbjct: 302 LEQIMKDRWMN 312
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 74.3 bits (181), Expect = 7e-13
Identities = 57/213 (26%), Positives = 94/213 (43%), Gaps = 12/213 (5%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHD 554
KVYA+K +S E + S F E + N VV+L L+++ME
Sbjct: 100 KVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPG- 158
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDF 613
++ S ++ R++ E++ + +H +H D+KP N + K G LK+ DF
Sbjct: 159 -GDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADF 217
Query: 614 GIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCIL 673
G + + + D +GTP+Y++PE L + DG G+ D WS G L
Sbjct: 218 GTCMKMNKEGM-VRCDTAVGTPDYISPEVLKSQG---GDG-----YYGRECDWWSVGVFL 268
Query: 674 YQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPE 706
Y+M+ G P+ IMN + +P+
Sbjct: 269 YEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPD 301
>Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 496
Score = 74.3 bits (181), Expect = 7e-13
Identities = 60/226 (26%), Positives = 104/226 (45%), Gaps = 37/226 (16%)
Query: 495 KVYALKRVS-FDEFDESSIDGFKGEIELLKKLENK------------QRVVKLIDYHMGQ 541
KV+A+K ++ ++ + F+ E ++L +NK + ++DY++G
Sbjct: 101 KVFAMKILNKWEMLKRAETACFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGG 160
Query: 542 GVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANF 601
+L LL + + ++P D R++ EM+ + VH VH D+KP N
Sbjct: 161 DLLTLLSKFED-----------RLPED--MARFYLAEMVIAIDSVHQLHYVHRDIKPDNI 207
Query: 602 VF-VKGMLKIIDFGIA-NAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWK 659
+ + G +++ DFG + D TV +GTP+Y++PE L AM E K +
Sbjct: 208 LMDMNGHIRLADFGSCLKLMEDGTVQ--SSVAVGTPDYISPEILQAM-------EDGKGR 258
Query: 660 VGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYP 705
G D WS G +Y+M+YG+ P+ IMN + +P
Sbjct: 259 YGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFP 304
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 74.3 bits (181), Expect = 7e-13
Identities = 73/275 (26%), Positives = 116/275 (41%), Gaps = 30/275 (10%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMEC--GE 552
K+ A+K ++ + E + EI +L K+++ +V L D + G L+L+M+ G
Sbjct: 44 KLVAIKCIAKEAL-EGKEGSMENEIAVLHKIKHPN-IVALDDIYESGGHLYLIMQLVSGG 101
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK----GML 608
+++ + D R FQ ++ VK +HD IVH DLKP N ++ +
Sbjct: 102 ELFDRIVEKGFYTERDAS--RLIFQ-VLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKI 158
Query: 609 KIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWS 668
I DFG++ +V GTP Y+APE L A+ K D WS
Sbjct: 159 MISDFGLSKMEDPGSV---LSTACGTPGYVAPEVL------------AQKPYSKAVDCWS 203
Query: 669 CGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLER 728
G I Y ++ G PP+ I+ + + P D I + D IR +E+
Sbjct: 204 IGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDD----ISDSAKDFIRHLMEK 259
Query: 729 NPISRVTIDQLLSGALINPVTVTKFFIHDLIKNAV 763
+P R T +Q L I T IH + +
Sbjct: 260 DPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQI 294
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 74.3 bits (181), Expect = 7e-13
Identities = 66/254 (25%), Positives = 109/254 (41%), Gaps = 27/254 (10%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH- 553
K A+K + + + SS+ E+ ++K L N +VKL + + L+L+ME
Sbjct: 77 KEVAVKIIDKTQLNSSSLQKLFREVRIMKVL-NHPNIVKLFEVIETEKTLYLVMEYASGG 135
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIID 612
++ L ++ + R F++++ V+ H IVH DLK N + M +KI D
Sbjct: 136 EVFDYLVAHGRMK--EKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIAD 193
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG +N + T D G+P Y APE Q K G DVWS G I
Sbjct: 194 FGFSN---EFTFGNKLDTFCGSPPYAAPELF-----------QGKKYDGPEVDVWSLGVI 239
Query: 673 LYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPIS 732
LY +V G P+ ++ +IP+ ++ + +I NP
Sbjct: 240 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLI--------LNPSK 291
Query: 733 RVTIDQLLSGALIN 746
R T++Q++ +N
Sbjct: 292 RGTLEQIMKDRWMN 305
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 74.3 bits (181), Expect = 7e-13
Identities = 69/279 (24%), Positives = 117/279 (41%), Gaps = 40/279 (14%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHD 554
+V ALK++ D E EI LLK+L N +VKL+D + L+L+ E D
Sbjct: 28 EVVALKKIRLDTETEGVPSTAIREISLLKEL-NHPNIVKLLDVIHTENKLYLVFEFLHQD 86
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDF 613
L + + + ++ + ++++ + H ++H DLKP N + +G +K+ DF
Sbjct: 87 LKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADF 146
Query: 614 GIANA--VPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGC 671
G+A A VP T +++ T Y APE L+ + D+WS GC
Sbjct: 147 GLARAFGVPVRTYT----HEVVTLWYRAPEILLGCKY-----------YSTAVDIWSLGC 191
Query: 672 ILYQMVYGKPPYGTFQGNNRLYAIMN----------------PDVKIPYPE--KDSFGTV 713
I +MV + + ++L+ I PD K +P+ + F V
Sbjct: 192 IFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKV 251
Query: 714 IPRTVID---TIRSCLERNPISRVTIDQLLSGALINPVT 749
+P D + L +P R++ L+ VT
Sbjct: 252 VPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVT 290
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 74.3 bits (181), Expect = 7e-13
Identities = 77/301 (25%), Positives = 132/301 (43%), Gaps = 55/301 (18%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKL----------IDYHMGQGVL 544
++ ALK+V D E EI++L++L + Q ++ + +D+ +G
Sbjct: 729 EMVALKKVRLDNEKEGFPITAIREIKILRQLTH-QSIINMKEIVTDKEDALDFKKDKGAF 787
Query: 545 FLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFV 604
+L+ E +HDL +L + + F+ ++ +++++ + H + +H D+K +N +
Sbjct: 788 YLVFEYMDHDLMGLL-ESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLN 846
Query: 605 -KGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKP 663
+G +K+ DFG+A Y N++ T Y PE L+ GE+ +
Sbjct: 847 NRGQIKLADFGLARLYSSEESRPYT-NKVITLWYRPPELLL--------GEE---RYTPA 894
Query: 664 SDVWSCGCILYQMVYGKPPYGTFQGNNRLYAI-------------MNPDV-KIPY----- 704
DVWSCGCIL ++ KP FQ N L + + PDV K+PY
Sbjct: 895 IDVWSCGCILGELFTKKP---IFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMK 951
Query: 705 PEK-------DSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALINPVTVTKFFIHD 757
P+K + F IP +D L +P R T +Q L + V +K D
Sbjct: 952 PKKQYRRKLREEF-VFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPD 1010
Query: 758 L 758
L
Sbjct: 1011 L 1011
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 74.3 bits (181), Expect = 7e-13
Identities = 77/301 (25%), Positives = 132/301 (43%), Gaps = 55/301 (18%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKL----------IDYHMGQGVL 544
++ ALK+V D E EI++L++L + Q ++ + +D+ +G
Sbjct: 729 EMVALKKVRLDNEKEGFPITAIREIKILRQLTH-QSIINMKEIVTDKEDALDFKKDKGAF 787
Query: 545 FLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFV 604
+L+ E +HDL +L + + F+ ++ +++++ + H + +H D+K +N +
Sbjct: 788 YLVFEYMDHDLMGLL-ESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLN 846
Query: 605 -KGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKP 663
+G +K+ DFG+A Y N++ T Y PE L+ GE+ +
Sbjct: 847 NRGQIKLADFGLARLYSSEESRPYT-NKVITLWYRPPELLL--------GEE---RYTPA 894
Query: 664 SDVWSCGCILYQMVYGKPPYGTFQGNNRLYAI-------------MNPDV-KIPY----- 704
DVWSCGCIL ++ KP FQ N L + + PDV K+PY
Sbjct: 895 IDVWSCGCILGELFTKKP---IFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMK 951
Query: 705 PEK-------DSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALINPVTVTKFFIHD 757
P+K + F IP +D L +P R T +Q L + V +K D
Sbjct: 952 PKKQYRRKLREEF-VFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPD 1010
Query: 758 L 758
L
Sbjct: 1011 L 1011
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 74.3 bits (181), Expect = 7e-13
Identities = 66/278 (23%), Positives = 115/278 (40%), Gaps = 29/278 (10%)
Query: 472 YEKVELLXXXXXXXXXXXXXXDHKVYALKRVSFDEF-DESSIDGFKGEIELLKKLENKQR 530
YE +E L ++ A+K + D+ DE + + EIE++ L N
Sbjct: 53 YEFLETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSL-NHPH 111
Query: 531 VVKLIDYHMGQGVLFLLMECGEH-DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDA 589
++ + + + ++ME DL +++R ++ R+ F++++ V H
Sbjct: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQL--SEREARHFFRQIVSAVHYCHQN 169
Query: 590 DIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNF 648
+VH DLK N + G +KI DFG++N + + G+P Y +PE + +
Sbjct: 170 RVVHRDLKLENILLDANGNIKIADFGLSNL---YHQGKFLQTFCGSPLYASPEIVNGKPY 226
Query: 649 TRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKD 708
T G D WS G +LY +V+G P+ + I N + P D
Sbjct: 227 T-----------GPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSD 275
Query: 709 SFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALIN 746
+ G IR L NP R T++ + S +N
Sbjct: 276 ACG---------LIRWLLMVNPTRRATLEDVASHWWVN 304
>CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 572
Score = 74.3 bits (181), Expect = 7e-13
Identities = 90/369 (24%), Positives = 155/369 (41%), Gaps = 48/369 (13%)
Query: 387 VPEDYRPPFFSHRKAPSPH-----DSKPFKKVEIVEPPKSTVEVIPLKSEG-CDVSSKLN 440
+P Y PP H + P+ +P + + I PK E IP S+G V ++
Sbjct: 208 MPPSYAPPPVPHGETPADIVPPAIPDRPARTLSIYTKPKEEEEKIPDLSKGQFGVQARGQ 267
Query: 441 KGDNYLNYNGSFDTKKRTSYAVPTITVNGTAYEKVELLXXXXXXXXXXXXXXDHKV-YAL 499
K + + TK RT + +I Y KV+ + + A+
Sbjct: 268 KAKKKMT-DAEVLTKLRT---IVSIGNPDRKYRKVDKIGSGASGSVYTAIEISTEAEVAI 323
Query: 500 KRVSFDEFDESSIDGFKGEI---ELLKKLENKQ-RVVKLIDYHMGQGVLFLLME-CGEHD 554
K+++ D K E+ E+L ENK +V +D ++ L+++ME
Sbjct: 324 KQMNLK-------DQPKKELIINEILVMRENKHANIVNYLDSYLVCDELWVVMEYLAGGS 376
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDF 613
L+ V+T+ + + +E+++ ++ +H ++H D+K N + + G +K+ DF
Sbjct: 377 LTDVVTE---CQMEDGIIAAVCREVLQALEFLHSRHVIHRDIKSDNILLGMDGSVKLTDF 433
Query: 614 GI-ANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
G A P+ R +GTP +MAPE + + G DVWS G +
Sbjct: 434 GFCAQLSPEQRK---RTTMVGTPYWMAPEVVTRKQY------------GPKVDVWSLGIM 478
Query: 673 LYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPIS 732
+MV G+PPY +Y I + K +P +DS + D + S LE +
Sbjct: 479 AIEMVEGEPPYLNENPLRAIYLIAT-NGKPDFPGRDSMTLLFK----DFVDSALEVQVEN 533
Query: 733 RVTIDQLLS 741
R + QLL+
Sbjct: 534 RWSASQLLT 542
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 74.3 bits (181), Expect = 7e-13
Identities = 63/233 (27%), Positives = 99/233 (42%), Gaps = 38/233 (16%)
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIID 612
+L + ++ ++ D R FQ++I V+ H +VH DLKP N + + +KI D
Sbjct: 104 ELFDYIVEKGRLQEDE--ARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSRCNIKIAD 161
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG++N + D + G+PNY APE + K G DVWSCG I
Sbjct: 162 FGLSNVMRD---GHFLKTSCGSPNYAAPEVI-----------SGKLYAGPEVDVWSCGVI 207
Query: 673 LYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPIS 732
LY ++ G P+ N I +P +IPR +I +P+
Sbjct: 208 LYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEARDLIPRMLI--------VDPVK 259
Query: 733 RVTIDQLLSG-----------ALINPVTV--TKFFIHDLIKNAVNYGCDQKHV 772
R+TI ++ A+ P TV K ++++ VN G D+ V
Sbjct: 260 RITIPEIRQHRWFQTHLPRYLAVSPPDTVEQAKKINEEIVQEVVNMGFDRNQV 312
>At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 541
Score = 74.3 bits (181), Expect = 7e-13
Identities = 67/264 (25%), Positives = 116/264 (43%), Gaps = 52/264 (19%)
Query: 495 KVYALKRVSFDEF-DESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGE 552
K YA K +S + ++ D + EI++++ L + +V+ + + + L+ME C
Sbjct: 115 KKYACKSISKKKLVTKADKDDMRREIQIMQHLSGQPNIVEFKGAYEDEKAVNLVMELCAG 174
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQE---------MIKCVKVVHDADIVHSDLKPANFVF 603
+L FD + H+ E ++ VK+ H ++H DLKP NF+
Sbjct: 175 GEL-----------FDRIIAKGHYTERAAASVCRQIVNVVKICHFMGVLHRDLKPENFLL 223
Query: 604 V----KGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWK 659
K ++K DFG++ + + V YRD +G+ Y+APE L + +
Sbjct: 224 SSKDEKALIKATDFGLSVFIEEGKV--YRDI-VGSAYYVAPEVL-------------RRR 267
Query: 660 VGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKI---PYPEKDSFGTVIPR 716
GK D+WS G ILY ++ G PP+ AI+ + P+P I
Sbjct: 268 YGKEVDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGHIDFESQPWPS-------ISS 320
Query: 717 TVIDTIRSCLERNPISRVTIDQLL 740
+ D +R L +P R++ +L
Sbjct: 321 SAKDLVRRMLTADPKRRISAADVL 344
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 74.3 bits (181), Expect = 7e-13
Identities = 61/213 (28%), Positives = 108/213 (50%), Gaps = 24/213 (11%)
Query: 495 KVYALKRVSFDEFDESS-IDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMEC--G 551
++YA+K + D+ E + + K E ++L K+++ +V+L + L+L+++ G
Sbjct: 164 EIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDHPF-IVQLKYSFQTKYRLYLVLDFING 222
Query: 552 EHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKI 610
H Q+ Q F + R + E++ V +H+ I+H DLKP N + V G + +
Sbjct: 223 GHLFFQLYHQGL---FREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDVDGHVML 279
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG+A ++T + ++ GT YMAPE + R G K +D WS G
Sbjct: 280 TDFGLAKEFEENTRS---NSMCGTTEYMAPEIV------RGKGHD------KAADWWSVG 324
Query: 671 CILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIP 703
+LY+M+ GKPP+ +G + I+ +K+P
Sbjct: 325 ILLYEMLTGKPPFLGSKGKIQ-QKIVKDKIKLP 356
>At1g53570 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 74.3 bits (181), Expect = 7e-13
Identities = 62/253 (24%), Positives = 113/253 (44%), Gaps = 25/253 (9%)
Query: 499 LKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQ 557
+K +S D+ + + EI LL +L + +V+ + + L + +E + +
Sbjct: 245 VKVISDDQTSKECLKQLNQEINLLNQLCHPN-IVQYYGSELSEETLSVYLEYVSGGSIHK 303
Query: 558 VLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANF-VFVKGMLKIIDFGIA 616
+L F ++ + ++++ + +H + VH D+K AN V G +K+ DFG+A
Sbjct: 304 LLKDYGS--FTEPVIQNYTRQILAGLAYLHGRNTVHRDIKGANILVDPNGEIKLADFGMA 361
Query: 617 NAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQM 676
V + + + G+P +MAPE +++ N + D+WS GC + +M
Sbjct: 362 KHVTAFSTML---SFKGSPYWMAPEVVMSQNGYTH-----------AVDIWSLGCTILEM 407
Query: 677 VYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTI 736
KPP+ F+G ++ I N P+ + + IR CL+RNP R T
Sbjct: 408 ATSKPPWSQFEGVAAIFKIGNSKDTPEIPDH------LSNDAKNFIRLCLQRNPTVRPTA 461
Query: 737 DQLLSGALINPVT 749
QLL + T
Sbjct: 462 SQLLEHPFLRNTT 474
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 74.3 bits (181), Expect = 7e-13
Identities = 59/192 (30%), Positives = 101/192 (51%), Gaps = 20/192 (10%)
Query: 494 HKVYALKRVSFD-EFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGV--LFLLMEC 550
+++ ALK+V D E D I G + EI +LK+ + + +V+L + +G+ + +FL+M+
Sbjct: 76 NEIVALKKVRMDQEKDGLPISGLR-EIMILKQCHH-ENIVRLREVVVGKSLDSIFLVMDF 133
Query: 551 GEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFV-KGMLK 609
E DL+ VL S+ PF V+ +++K +K +H ++H DLK +N + KG +K
Sbjct: 134 CEQDLASVLDNMSQ-PFTESEVKCITLQVLKALKYLHSRFMIHRDLKVSNLLMTDKGCIK 192
Query: 610 IIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
+ DFG+A + + Q+ T Y APE L+ D+W+
Sbjct: 193 VADFGLARMFSNPPKPM--TPQMVTLWYRAPELLLGCRTHTT-----------AVDMWAF 239
Query: 670 GCILYQMVYGKP 681
GCIL +++ GKP
Sbjct: 240 GCILGELLLGKP 251
>SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase
Length = 532
Score = 73.9 bits (180), Expect = 9e-13
Identities = 61/245 (24%), Positives = 112/245 (44%), Gaps = 27/245 (11%)
Query: 498 ALKRVSFDEF-DESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLS 556
ALK V DE D+ + + E+ +L++L + ++ L L +E + DL
Sbjct: 50 ALKMVYNDELEDKDTWKRLQREVTILRQLHHPN-IITLYQVFRVPKYTVLALEYMDTDLH 108
Query: 557 QVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGML-KIIDFGI 615
++ + +++ D R F++++ + H + H DLK N + K ++ K+ DFG+
Sbjct: 109 SMVVKHNRL--DECTTRKIFRQIVHAIDYCHLHRVAHRDLKLENILLNKDLVVKLTDFGL 166
Query: 616 ANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQ 675
+N + D + + GTP+Y APE + Q ++ G DVW CG +LY
Sbjct: 167 SNFMLDGS---FLSTSCGTPHYAAPEVI-----------QGRYYDGCDVDVWGCGILLYL 212
Query: 676 MVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVT 735
M+ G+ P+ +N L + IP + + + D IR L P SR+
Sbjct: 213 MLVGEFPFEDVTISNVLSRVCKGIYTIP--------SFVSSSASDLIRQMLMVLPTSRIK 264
Query: 736 IDQLL 740
+ +++
Sbjct: 265 VAEIM 269
>Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 414
Score = 73.9 bits (180), Expect = 9e-13
Identities = 59/230 (25%), Positives = 110/230 (47%), Gaps = 28/230 (12%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLME--CGEHDLSQVLTQRSKIPFDTEFVRYH 575
EI +L+ ++ V+ L + + + L++E G Q + R + F + V+
Sbjct: 108 EIAVLELAQDNPWVINLHEVYETASEMILVLEYAAGGEIFDQCVADREEA-FKEKDVQRL 166
Query: 576 FQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKIIDFGIANAVPDHTVNIYRDNQ 631
+++++ V +H D+VH DLKP N + G +KI+DFG++ + + +
Sbjct: 167 MRQILEGVHFLHTRDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKN---SEELREI 223
Query: 632 IGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNR 691
+GTP Y+APE L + + +D+WS G + Y M+ G P F GN++
Sbjct: 224 MGTPEYVAPEIL------------SYDPISMATDMWSIGVLTYVMLTGISP---FLGNDK 268
Query: 692 LYAIMN-PDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
+N + + Y E++ V+ + +D IR+ L + P R T ++ L
Sbjct: 269 QETFLNISQMNLSYSEEEF--DVLSESAVDFIRTLLVKKPEDRATAEECL 316
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 73.9 bits (180), Expect = 9e-13
Identities = 49/174 (28%), Positives = 87/174 (49%), Gaps = 18/174 (10%)
Query: 512 IDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTE 570
+D K EI ++K + + +V+L + +++++E +L + + ++ +
Sbjct: 53 VDQIKREISIMKIVRHPN-IVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRL--EES 109
Query: 571 FVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYRD 629
R +FQ+++ V H + H DLKP N + G LK+ DFG++ A+P V + R
Sbjct: 110 ESRKYFQQLVDAVAHCHCKGVYHRDLKPENLLLDTNGNLKVSDFGLS-ALPQEGVELLRT 168
Query: 630 NQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPY 683
GTPNY+APE L + G +D+WSCG IL+ ++ G P+
Sbjct: 169 T-CGTPNYVAPEVLSGQGYD-----------GSAADIWSCGVILFVILAGYLPF 210
>At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 503
Score = 73.9 bits (180), Expect = 9e-13
Identities = 68/247 (27%), Positives = 104/247 (41%), Gaps = 53/247 (21%)
Query: 512 IDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTE 570
I+ K E+ ++K L +V L + + L+ME C +L FD
Sbjct: 96 IEDVKREVAIMKHLPKSSSIVTLKEACEDDNAVHLVMELCEGGEL-----------FDRI 144
Query: 571 FVRYHFQE---------MIKCVKVVHDADIVHSDLKPANFVFVK----GMLKIIDFGIAN 617
R H+ E +++ V++ H ++H DLKP NF+F LK IDFG++
Sbjct: 145 VARGHYTERAAAGVTKTIVEVVQLCHKHGVIHRDLKPENFLFANKKENSPLKAIDFGLSI 204
Query: 618 AV-PDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQM 676
P + +G+P YMAPE L K G D+WS G ILY +
Sbjct: 205 FFKPGEKFS----EIVGSPYYMAPEVL-------------KRNYGPEIDIWSAGVILYIL 247
Query: 677 VYGKPPYGTFQGNNRLYAIMNPDV---KIPYPEKDSFGTVIPRTVIDTIRSCLERNPISR 733
+ G PP+ AI+ + + P+P I T + +R LE +P R
Sbjct: 248 LCGVPPFWAESEQGVAQAILRGVIDFKREPWPN-------ISETAKNLVRQMLEPDPKRR 300
Query: 734 VTIDQLL 740
+T Q+L
Sbjct: 301 LTAKQVL 307
>At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 73.9 bits (180), Expect = 9e-13
Identities = 75/266 (28%), Positives = 121/266 (45%), Gaps = 39/266 (14%)
Query: 511 SIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMEC--GEHDLSQVLTQRSKIPFD 568
SI+ + E++LLK L +VK D +F++ME G L +L + + P +
Sbjct: 186 SIEDVRREVKLLKALSGHSHMVKFYDVFEDSDNVFVVMELCEGGELLDSILARGGRYP-E 244
Query: 569 TEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKIIDFGIAN-AVPDHT 623
E R Q ++ H +VH DLKP NF+F +LK+IDFG+++ A D
Sbjct: 245 AEAKRILVQ-ILSATAFFHLQGVVHRDLKPENFLFTSKNEDAVLKVIDFGLSDYARFDQR 303
Query: 624 VNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYG-KPP 682
+N + +G+ Y+APE L T +D+WS G I Y ++ G +P
Sbjct: 304 LN----DVVGSAYYVAPEVLHRSYSTE-------------ADIWSIGVISYILLCGSRPF 346
Query: 683 YG-TFQGNNRLYAIMNPDV-KIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
YG T R NP+ +P+P I D ++ L ++ R+T Q L
Sbjct: 347 YGRTESAIFRCVLRANPNFDDLPWPS-------ISPIAKDFVKRLLNKDHRKRMTAAQAL 399
Query: 741 SGALI---NPVTVTKFFIHDLIKNAV 763
+ + NP + F I+ L+K+ +
Sbjct: 400 AHPWLRDENPGLLLDFSIYKLVKSYI 425
>Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 360
Score = 73.9 bits (180), Expect = 9e-13
Identities = 66/256 (25%), Positives = 125/256 (48%), Gaps = 32/256 (12%)
Query: 497 YALKRVSFDEFDES---SIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH 553
+A+K V +F S S + K E + L++ +V+L++ + G+L+++ E +
Sbjct: 38 FAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPH-IVELLETYSSDGMLYMVFEFMDG 96
Query: 554 -DLSQVLTQRSKIPFD-TEFVRYHF-QEMIKCVKVVHDADIVHSDLKPANFVFVK----G 606
DL + +R+ F +E V H+ +++++ ++ HD +I+H D+KP +
Sbjct: 97 ADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSA 156
Query: 607 MLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDV 666
+K+ FG+A + + + ++GTP++MAPE + + GKP DV
Sbjct: 157 PVKLGGFGVAIQLGES--GLVAGGRVGTPHFMAPEVVKREPY------------GKPVDV 202
Query: 667 WSCGCILYQMVYG-KPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSC 725
W CG IL+ ++ G P YGT RL+ + +K Y + I + D +R
Sbjct: 203 WGCGVILFILLSGCLPFYGT---KERLFEGI---IKGKYKMNPRQWSHISESAKDLVRRM 256
Query: 726 LERNPISRVTIDQLLS 741
L +P R+T+ + L+
Sbjct: 257 LMLDPAERITVYEALN 272
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 73.6 bits (179), Expect = 1e-12
Identities = 64/231 (27%), Positives = 107/231 (45%), Gaps = 33/231 (14%)
Query: 517 GEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHF 576
GEI++ + + + +V ID ++L++E EH L ++ K + E VRY
Sbjct: 87 GEIKVHQSMSHPN-IVGFIDCFEDSTNIYLILELCEHKSLMELLRKRKQLTEPE-VRYLM 144
Query: 577 QEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVNIYRDNQIGTP 635
+++ +K +H ++H DLK N + + +KI DFG+A + D + GTP
Sbjct: 145 MQILGALKYMHKKRVIHRDLKLGNIMLDESNNVKIGDFGLAALLMDDEER--KMTICGTP 202
Query: 636 NYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAI 695
NY+APE L N E ++V D+WS G ++Y ++ GKPP+
Sbjct: 203 NYIAPEILF------NSKEGHSFEV----DLWSAGVVMYALLIGKPPF------------ 240
Query: 696 MNPDVKIPYPEKDSFGTVIPRTV------IDTIRSCLERNPISRVTIDQLL 740
+ +VK Y + + P V D I S L +P R +ID ++
Sbjct: 241 QDKEVKTIYRKIKANSYSFPSNVDISAEAKDLISSLLTHDPSIRPSIDDIV 291
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 73.6 bits (179), Expect = 1e-12
Identities = 77/293 (26%), Positives = 129/293 (43%), Gaps = 38/293 (12%)
Query: 450 GSFDTKKRTSYAVPTITVNGTAYEKVELLXXXXXXXXXXXXXXDHKVYALKRVSFDEFDE 509
G F TKK Y + T+ + KV+L D + K + E
Sbjct: 2 GLFGTKKIGKYEIGR-TIGEGNFAKVKLGYDTTNGTYVAVKIIDKALVIQKGL------E 54
Query: 510 SSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFD 568
S + K EI +K L N +V++ + + + ++ME LS L ++ D
Sbjct: 55 SQV---KREIRTMKLL-NHPNIVQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQKMKESD 110
Query: 569 TEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIY 627
R FQ++I V H+ + H DLKP N + KG LK+ DFG++ AVP +
Sbjct: 111 A---RKLFQQLIDAVDYCHNRGVYHRDLKPQNLLLDSKGNLKVSDFGLS-AVPKSGDML- 165
Query: 628 RDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQ 687
G+P Y+APE ++ ++ G DVWSCG IL++++ G PP+
Sbjct: 166 -STACGSPCYIAPELIMNKGYS-----------GAAVDVWSCGVILFELLAGYPPF---- 209
Query: 688 GNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
++ L + ++ Y F R + + L+ NP+SR+T+ +++
Sbjct: 210 DDHTLPVLYKKILRADYTFPPGFTGEQKRLIF----NILDPNPLSRITLAEII 258
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 73.6 bits (179), Expect = 1e-12
Identities = 55/193 (28%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 494 HKVYALKRVSFDEFDESSIDGFKGEIELLKKLEN----KQRVVKLIDYHMGQGVLFLLME 549
+K ALKR+ FD + SI EI +L+KL++ K + L+D+ L+L+ E
Sbjct: 126 NKTVALKRIRFDINNSESIKCIAREIIILRKLDHPNVIKLEGLMLVDH--DSSTLYLIFE 183
Query: 550 CGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGML 608
EHDL L+ + F V+ + +++++ + H ++H D+K +N + G+L
Sbjct: 184 YMEHDLLG-LSSLLGVHFSEPQVKCYMRQLLRGLDHCHTNHVLHRDMKSSNLLINGDGVL 242
Query: 609 KIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWS 668
KI DFG+A H ++ + T Y PE L+ + G D+WS
Sbjct: 243 KIADFGLATFFDPHN-SVPLTTHVATLWYRPPELLLGAS-----------HYGIGVDLWS 290
Query: 669 CGCILYQMVYGKP 681
GC++ ++ GKP
Sbjct: 291 TGCVIGELYAGKP 303
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 73.6 bits (179), Expect = 1e-12
Identities = 61/226 (26%), Positives = 107/226 (46%), Gaps = 25/226 (11%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTEFVRYHF 576
EIE +++L N V+K+ + + ++L++E +L L + ++ + R +F
Sbjct: 69 EIEAMRRLHNHPNVLKIHEVMATKSKIYLVVEYAAGGELFTKLIRFGRL--NESAARRYF 126
Query: 577 QEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDFGIANAVPDHTVNI-YRDNQIGT 634
Q++ + H I H D+KP N + K G LK+ DFG++ A+P+H N GT
Sbjct: 127 QQLASALSFCHRDGIAHRDVKPQNLLLDKQGNLKVSDFGLS-ALPEHRSNNGLLHTACGT 185
Query: 635 PNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYA 694
P Y APE + + DG +A D WSCG L+ ++ G P+ + + A
Sbjct: 186 PAYTAPEVIAQRGY---DGAKA--------DAWSCGVFLFVLLAGYVPF----DDANIVA 230
Query: 695 IMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
+ K Y F + I + I L+ NP +R++I+ ++
Sbjct: 231 MYRKIHKRDY----RFPSWISKPARSIIYKLLDPNPETRMSIEAVM 272
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 73.6 bits (179), Expect = 1e-12
Identities = 65/229 (28%), Positives = 111/229 (48%), Gaps = 36/229 (15%)
Query: 516 KGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMEC--GEHDLSQVLTQRSKIPFDTEFVR 573
K EI LK L++ +V+L + + + ++ME G ++++ D R
Sbjct: 66 KREIRTLKMLKHPH-IVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDG---R 121
Query: 574 YHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYRDNQI 632
FQ++I + H + H DLK N + KG +KI DFG++ A+P H +RD+ +
Sbjct: 122 KMFQQLIDGISYCHSKGVFHRDLKLENVLLDAKGHIKITDFGLS-ALPQH----FRDDGL 176
Query: 633 -----GTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQ 687
G+PNY+APE L + G SD+WSCG ILY ++ G P+
Sbjct: 177 LHTTCGSPNYVAPEVLANRGYD-----------GAASDIWSCGVILYVILTGCLPF---- 221
Query: 688 GNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTI 736
++R A++ + P + + RT+ I+ L+ NP++R+T+
Sbjct: 222 -DDRNLAVLYQKICKGDPPIPRWLSPGARTM---IKRMLDPNPVTRITV 266
>7300149 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 569
Score = 73.6 bits (179), Expect = 1e-12
Identities = 72/264 (27%), Positives = 120/264 (45%), Gaps = 36/264 (13%)
Query: 503 SFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHM--GQGVLFLLMECGEHD-LSQVL 559
+ D ++SS D EI +LK +K +V +D ++ + L+++ME + L+ V+
Sbjct: 323 TIDMKNQSSKDLILTEIRVLKDFNHKN-LVNFLDAYLLEPEDQLWVVMEYMDGGPLTDVV 381
Query: 560 TQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGI-AN 617
T+ V +E + + +H I+H D+K N + + G +K+ DFG AN
Sbjct: 382 TETVMKERQIACV---CRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCAN 438
Query: 618 AVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMV 677
D R +GTP +MAPE + + K GK D+WS G + +M+
Sbjct: 439 IEGDEK----RQTMVGTPYWMAPEVVT------------RKKYGKKVDIWSIGIMAIEMI 482
Query: 678 YGKPPYGTFQGNNRLYAIM---NPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRV 734
G+PPY LY I PD+K S+ + P + D + CL+ R
Sbjct: 483 EGQPPYLYETPLRALYLIAANGRPDIK-------SWDKLSP-NLQDFLDRCLQVEVDRRA 534
Query: 735 TIDQLLSGALINPVTVTKFFIHDL 758
T D+LLS +N + K + ++
Sbjct: 535 TADELLSHPFLNDCSEVKALVPNI 558
>7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1726
Score = 73.6 bits (179), Expect = 1e-12
Identities = 65/242 (26%), Positives = 115/242 (46%), Gaps = 20/242 (8%)
Query: 508 DESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIP 566
DE ++ EI++L ++++ +V+L + L++L+E C L ++ + K P
Sbjct: 72 DEENLSDHMVEIDILSEIKHPN-IVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEK-P 129
Query: 567 FDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVN 625
+ Y + M + + +H ++H DLK N + ++G +K+ DFG++ A HT+
Sbjct: 130 LTEPQIAYVCKHMTEGLTFLHRNKVIHRDLKAGNVLLTMEGGVKLADFGVS-AKNKHTMQ 188
Query: 626 IYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGT 685
+ D IGTP +MAPE ++ F N + KV D+WS G L ++ +PP
Sbjct: 189 KH-DTFIGTPYWMAPELVLCETFRDNPYDH---KV----DIWSLGITLIELAQMEPPNSE 240
Query: 686 FQGNNRLYAIMNPD-VKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGAL 744
L I + K+ P + S + D ++ L ++P R T D L+ A
Sbjct: 241 MSPMRVLLKIQKSEPPKLEQPSRWS------KEFNDFLKKSLVKDPQVRPTTDVLMQHAF 294
Query: 745 IN 746
IN
Sbjct: 295 IN 296
>At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 225
Score = 73.6 bits (179), Expect = 1e-12
Identities = 53/206 (25%), Positives = 97/206 (46%), Gaps = 30/206 (14%)
Query: 499 LKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQ 557
+K + + + D E+E L +++ +++L+ L +++E C LS
Sbjct: 33 MKCFDLSKLNRNLRDCLNNELEFLSSVDHPN-IIRLLHVSQDDDFLVMVLEYCDGGTLSS 91
Query: 558 VLTQRSKIPFDTEFVRYHFQEMIKC-VKVVHDADIVHSDLKPANFVFVKG-----MLKII 611
+ + ++ D + F + I ++++HD I+H DLKP N + + G +LKI
Sbjct: 92 YIQRYGRVEED---IAKRFMKQIGAGLEIIHDNHIIHRDLKPEN-ILIDGSGDDLVLKIA 147
Query: 612 DFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGC 671
DF +A + Y + G+P YMAPE L + +D+WS G
Sbjct: 148 DFSLARKLHPGK---YLETVCGSPFYMAPEVLQFQRYNEK------------ADMWSVGA 192
Query: 672 ILYQMVYGKPPYGTFQGNNRLYAIMN 697
IL+++++G PP F+GNN + + N
Sbjct: 193 ILFELLHGYPP---FRGNNNVQVLRN 215
>Hs20547806 [R] KOG0589 Serine/threonine protein kinase
Length = 489
Score = 73.2 bits (178), Expect = 1e-12
Identities = 61/254 (24%), Positives = 112/254 (44%), Gaps = 25/254 (9%)
Query: 494 HKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGE 552
++++A+K + + S+ + E LL K+++ +V + +G L+++ME C
Sbjct: 27 NQMFAMKEIRLPK-SFSNTQNSRKEAVLLAKMKHPN-IVAFKESFEAEGHLYIVMEYCDG 84
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLKII 611
DL Q + Q+ F + + F +M V +H ++H D+K N F+ G +K+
Sbjct: 85 GDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHKKRVLHRDIKSKNIFLTQNGKVKLG 144
Query: 612 DFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGC 671
DFG A + + + +GTP Y+ PE + + SD+WS GC
Sbjct: 145 DFGSARLLSNPMA--FACTYVGTPYYVPPEIWENLPYNNK------------SDIWSLGC 190
Query: 672 ILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPI 731
ILY++ K P+ N + + + P P S+ ++ +RNP
Sbjct: 191 ILYELCTLKHPFQANSWKNLILKVCQGCIS-PLPSHYSYELQF------LVKQMFKRNPS 243
Query: 732 SRVTIDQLLSGALI 745
R + LLS ++
Sbjct: 244 HRPSATTLLSRGIV 257
>Hs20070158 [T] KOG0201 Serine/threonine protein kinase
Length = 443
Score = 73.2 bits (178), Expect = 1e-12
Identities = 64/278 (23%), Positives = 119/278 (42%), Gaps = 26/278 (9%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHD 554
KV A+K + +E E I+ + EI +L + ++ V K ++ L+++ME
Sbjct: 60 KVVAIKIIDLEEA-EDEIEDIQQEITVLSQCDSPY-VTKYYGSYLKDTKLWIIMEYLGGG 117
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDF 613
+ L + P D + +E++K + +H +H D+K AN + + G +K+ DF
Sbjct: 118 SALDLLEPG--PLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADF 175
Query: 614 GIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCIL 673
G+A + D I R+ +GTP +MAPE + + +D+WS G
Sbjct: 176 GVAGQLTD--TQIKRNTFVGTPFWMAPEVIKQSAYDSK------------ADIWSLGITA 221
Query: 674 YQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISR 733
++ G+PP+ L+ IP + + + + + +CL + P R
Sbjct: 222 IELARGEPPHSELHPMKVLFL-------IPKNNPPTLEGNYSKPLKEFVEACLNKEPSFR 274
Query: 734 VTIDQLLSGALINPVTVTKFFIHDLIKNAVNYGCDQKH 771
T +LL I ++ +LI + +Q H
Sbjct: 275 PTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAEQSH 312
>Hs11140819 [T] KOG1151 Tousled-like protein kinase
Length = 749
Score = 73.2 bits (178), Expect = 1e-12
Identities = 77/275 (28%), Positives = 119/275 (43%), Gaps = 44/275 (16%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLF--LLMECGE 552
K++ L + DE E+ E + K+L++ R+VKL DY F +L C
Sbjct: 468 KIHQLNKNWRDEKKENYHKHACREYRIHKELDHP-RIVKLYDYFSLDTDSFCTVLEYCEG 526
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDAD--IVHSDLKPANFVFVKGM--- 607
+DL L Q K+ + E R +++ +K +++ I+H DLKP N + V G
Sbjct: 527 NDLDFYLKQH-KLMSEKE-ARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACG 584
Query: 608 -LKIIDFGIANAVPDHTVNIYRDNQI-----GTPNYMAPETLVAMNFTRNDGEQAKWKVG 661
+KI DFG++ + D + N ++ GT Y+ PE V G++ K+
Sbjct: 585 EIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVV-------GKEPP-KIS 636
Query: 662 KPSDVWSCGCILYQMVYGKPPYG-------TFQGNNRLYA--IMNPDVKIPYPEKDSFGT 712
DVWS G I YQ +YG+ P+G Q N L A + P + PE +F
Sbjct: 637 NKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAF-- 694
Query: 713 VIPRTVIDTIRSCLERNPISRVTIDQLLSGALINP 747
IR CL R+ + QL + P
Sbjct: 695 ---------IRRCLAYRKRDRIDVQQLACDPYLLP 720
>CE11916 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1548
Score = 73.2 bits (178), Expect = 1e-12
Identities = 51/202 (25%), Positives = 99/202 (48%), Gaps = 23/202 (11%)
Query: 526 ENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKV 585
++++ + ++DY++G +L LL + +H IP +++ EM+ +
Sbjct: 151 QDEKNLYFVMDYYIGGDMLTLLSKFVDH-----------IP--ESMAKFYIAEMVLAIDS 197
Query: 586 VHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLV 644
+H VH D+KP N + ++G +++ DFG + ++ + +GTP+Y++PE L
Sbjct: 198 LHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADG-SVASNVAVGTPDYISPEILR 256
Query: 645 AMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPY 704
AM E + + GK D WS G +Y+M+YG P+ + + + IM+ + +
Sbjct: 257 AM-------EDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDF 309
Query: 705 PEKDSFGTVIPRTVIDTIRSCL 726
P+ D V+ D IR +
Sbjct: 310 PD-DEIDWVVSEEAKDLIRQLI 330
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 73.2 bits (178), Expect = 1e-12
Identities = 67/289 (23%), Positives = 121/289 (41%), Gaps = 42/289 (14%)
Query: 472 YEKVELLXXXXXXXXXXXXXX-DHKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQR 530
YEKVE + ++ ALK++ ++ DE EI LLK++++
Sbjct: 4 YEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHSN- 62
Query: 531 VVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDAD 590
+VK D + L+L+ E + DL + + D ++ + ++++ + H
Sbjct: 63 IVKYDDVVHSEKRLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAYCHSHR 122
Query: 591 IVHSDLKPANFVFVK--GMLKIIDFGIANA--VPDHTVNIYRDNQIGTPNYMAPETLVAM 646
++H DLKP N + + LK+ DFG+A A +P T +++ T Y APE L+
Sbjct: 123 VLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFT----HEVVTLWYRAPEILLGS 178
Query: 647 NFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMN--------- 697
+ P D+WS GCI +M+ KP + ++L+ I
Sbjct: 179 H-----------HYSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDT 227
Query: 698 -------PDVKIPYP-----EKDSFGTVIPRTVIDTIRSCLERNPISRV 734
PD K +P + ++F + +D + L +P R+
Sbjct: 228 WRGVTSLPDYKSAFPKWKPTDLETFVPNLDPDGVDLLSKMLLMDPTKRI 276
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 72.8 bits (177), Expect = 2e-12
Identities = 51/186 (27%), Positives = 84/186 (44%), Gaps = 32/186 (17%)
Query: 519 IELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQE 578
I + ++ Q++ ++DY G G LF L+ R F +++ E
Sbjct: 148 IRMWGTFQDAQQIFMIMDYIEG-GELFSLL-------------RKSQRFPNPVAKFYAAE 193
Query: 579 MIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDFGIANAVPDHTVNIYRDNQIGTPNY 637
+ ++ +H DI++ DLKP N + K G +KI DFG A VPD T + GTP+Y
Sbjct: 194 VCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTL-----CGTPDY 248
Query: 638 MAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMN 697
+APE + + K D WS G ++Y+M+ G P+ I+N
Sbjct: 249 IAPEVVSTKPY------------NKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILN 296
Query: 698 PDVKIP 703
+++ P
Sbjct: 297 AELRFP 302
>SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase
Length = 312
Score = 72.8 bits (177), Expect = 2e-12
Identities = 63/246 (25%), Positives = 108/246 (43%), Gaps = 24/246 (9%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHD 554
K+ ALK V D + I+ EI L L N + K + L++ ME +
Sbjct: 30 KIVALKVVDLDA-TKDQIETLTQEINFLIDL-NSVHITKYYASFVDGFRLWITMEYCDGG 87
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-GMLKIIDF 613
L + S F + +++++ + +H +H D+K AN + +K G++K+ DF
Sbjct: 88 SCLDLLKLSGT-FSERVIAEVMRQVLEALVYLHGQGKMHRDIKAANILTMKDGLVKLADF 146
Query: 614 GIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCIL 673
G++ + ++ D+ +GTP +MAPE + + +D+WS G
Sbjct: 147 GVSGQL--ESLRDKNDDFVGTPFWMAPEVVKQTGYNYK------------ADIWSLGITA 192
Query: 674 YQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISR 733
Y++ G+PPY L I P P E+ F R D + +CL++NP R
Sbjct: 193 YELATGEPPYSGIHPMKVLLLI--PKHSPPSLERSKFS----RAFCDFVSNCLKKNPKDR 246
Query: 734 VTIDQL 739
T + L
Sbjct: 247 ATAEYL 252
>SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1116
Score = 72.8 bits (177), Expect = 2e-12
Identities = 62/244 (25%), Positives = 116/244 (47%), Gaps = 27/244 (11%)
Query: 505 DEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRS 563
D+ + +D EI ++ L++ +V+ + + + + + +E + + L R+
Sbjct: 867 DQLRKDIVDSINAEISMIADLDHLN-IVQYLGFEKTETDISIFLEYVSGGSIGRCL--RN 923
Query: 564 KIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDH 622
PF+ + VR+ ++++ + +H I+H DLK N + G+ KI DFGI+ H
Sbjct: 924 YGPFEEQLVRFVSRQVLYGLSYLHSKGIIHRDLKADNLLIDFDGVCKISDFGISK----H 979
Query: 623 TVNIYRDNQI-----GTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMV 677
+ N+Y DN G+ +MAPE + ND + KV DVWS GC++ +M+
Sbjct: 980 SDNVY-DNDANLSMQGSIFWMAPEVI------HNDHQGYSAKV----DVWSLGCVVLEML 1028
Query: 678 YGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTID 737
G+ P+ T + ++ + + K P + V P I + +C N R T +
Sbjct: 1029 AGRRPWSTDEAIQAMFK-LGTEKKAPPIPSELVSQVSPE-AIQFLNACFTVNADVRPTAE 1086
Query: 738 QLLS 741
+LL+
Sbjct: 1087 ELLN 1090
>Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 72.8 bits (177), Expect = 2e-12
Identities = 55/185 (29%), Positives = 92/185 (49%), Gaps = 24/185 (12%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEH 553
+V A+K V+ +++S++ EIE+LK + + +V+L D+ ++L+ME C
Sbjct: 82 EVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPH-IVQLKDFQWDSDNIYLIMEFCAGG 140
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFV---FVKGMLKI 610
DLS+ + R +P + R Q++ ++ +H+ +I H DLKP N + K LK+
Sbjct: 141 DLSRFIHTRRILP--EKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKL 198
Query: 611 IDFGIANAV-PDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
DFG A + P ++ R G+P YMAPE + + D+WS
Sbjct: 199 ADFGFAQHMSPWDEKHVLR----GSPLYMAPEMVCQRQYDAR------------VDLWSM 242
Query: 670 GCILY 674
G ILY
Sbjct: 243 GVILY 247
>At5g40440 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 520
Score = 72.8 bits (177), Expect = 2e-12
Identities = 73/263 (27%), Positives = 119/263 (44%), Gaps = 38/263 (14%)
Query: 493 DHKVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMG-----QGVLFLL 547
+H++ ALK+++ F+ EI L + + L+D+H G + +
Sbjct: 105 NHRILALKKINI--FEREKRQQLLTEIRTLCEAPCHEG---LVDFHGAFYSPDSGQISIA 159
Query: 548 ME-CGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDA-DIVHSDLKPANFVF-V 604
+E L+ +L KIP +H ++++ + +H +VH D+KPAN + +
Sbjct: 160 LEYMNGGSLADILKVTKKIPEPVLSSLFH--KLLQGLSYLHGVRHLVHRDIKPANLLINL 217
Query: 605 KGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPS 664
KG KI DFGI+ + + +GT YM+PE + RND P+
Sbjct: 218 KGEPKITDFGISAGLENSMAMCA--TFVGTVTYMSPERI------RNDS------YSYPA 263
Query: 665 DVWSCGCILYQMVYGKPPYGTFQG--NNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTI 722
D+WS G L++ G+ PY +G N L + +P P P K F I
Sbjct: 264 DIWSLGLALFECGTGEFPYIANEGPVNLMLQILDDPS---PTPPKQEFSPEF----CSFI 316
Query: 723 RSCLERNPISRVTIDQLLSGALI 745
+CL+++P +R T DQLLS I
Sbjct: 317 DACLQKDPDARPTADQLLSHPFI 339
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 72.8 bits (177), Expect = 2e-12
Identities = 54/227 (23%), Positives = 103/227 (44%), Gaps = 28/227 (12%)
Query: 465 ITVNGTAYEKVELLXXXXXXXXXXXXXXDH-KVYALKRVSFDEFDESSIDGFKGEIELLK 523
+ + A+EK+E + + ++ ALK+V FD F+ S+ EI +L+
Sbjct: 114 VPLRSDAFEKLEKIGQGTYSNVFRAVETETGRIVALKKVRFDNFEPESVKFMAREILILR 173
Query: 524 KLENKQRVVKLIDYHMGQGVLFLLMECG--------EHDLSQVLTQRSKIPFDTEFVRYH 575
+L N ++KL +G++ + C EHDL+ +L+ I F T ++ +
Sbjct: 174 RL-NHPNIIKL------EGLITSKLSCNIQLVFEYMEHDLTGLLSS-PDIKFTTPQIKCY 225
Query: 576 FQEMIKCVKVVHDADIVHSDLKPANFVFV-KGMLKIIDFGIANAVPDHTVNIYRDNQIGT 634
++++ + H ++H D+K +N + +G+LK+ DFG+AN N G
Sbjct: 226 MKQLLSGLDHCHSRGVMHRDIKGSNLLLSNEGILKVADFGLANF----------SNSSGH 275
Query: 635 PNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKP 681
+V + + + G D+WS GC+ +++ GKP
Sbjct: 276 KKKPLTSRVVTLWYRPPELLLGATDYGASVDLWSVGCVFAELLLGKP 322
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 72.8 bits (177), Expect = 2e-12
Identities = 63/248 (25%), Positives = 110/248 (43%), Gaps = 28/248 (11%)
Query: 496 VYALKRVSFDEFDESSIDG-FKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECG-EH 553
V ALK + + ES+++ + EIE+ L + +++L Y ++L++E +
Sbjct: 179 VVALKVLFKRQIGESNVEHQVRREIEIQSHLRHPH-ILRLYAYFHDDVRIYLILEYAPQG 237
Query: 554 DLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIID 612
L L + FD + Q + + +H+ DI+H D+KP N + KG+LKI D
Sbjct: 238 TLFNALQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIAD 297
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG + H N R GT +Y+ PE + T+N D+WS G +
Sbjct: 298 FGWS----VHEPNSMRMTLCGTVDYLPPEMVQGKPHTKN------------VDLWSLGVL 341
Query: 673 LYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPIS 732
++++ G P+ + + I+ D K+P I + I L NP
Sbjct: 342 CFELLVGHAPFYSKNYDETYKKILKVDYKLP--------EHISKAASHLISKLLVLNPQH 393
Query: 733 RVTIDQLL 740
R+ +DQ++
Sbjct: 394 RLPLDQVM 401
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 72.8 bits (177), Expect = 2e-12
Identities = 59/218 (27%), Positives = 97/218 (44%), Gaps = 26/218 (11%)
Query: 524 KLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKC 582
KL ++KL +F++ME +L + + K+ R FQ++I
Sbjct: 81 KLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKL--QEHQARRFFQQIISG 138
Query: 583 VKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPE 641
V H IVH DLKP N + M +KI DFG++N + D + G+PNY APE
Sbjct: 139 VDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMMLDGE---FLRTSCGSPNYAAPE 195
Query: 642 TLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVK 701
+ K G D+WSCG ILY ++ G P+ + L+ + +
Sbjct: 196 VI-----------SGKLYAGPEVDIWSCGVILYALLCGTLPFDD-EHVPTLFRKIKSGI- 242
Query: 702 IPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQL 739
P PE + + V++ + L+ +P+ R I+++
Sbjct: 243 FPIPE------YLNKQVVNLVCQMLQVDPLKRANIEEI 274
>7290147 [T] KOG0583 Serine/threonine protein kinase
Length = 291
Score = 72.8 bits (177), Expect = 2e-12
Identities = 41/128 (32%), Positives = 67/128 (52%), Gaps = 15/128 (11%)
Query: 575 HFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYRDNQIG 633
+F++M+ ++ +H ++H D+KP N + +KI DFGIAN H + +G
Sbjct: 117 YFRDMVVGLEYLHIRCVIHRDIKPENMLLDANDRVKIADFGIANV---HAPSTQLQAGMG 173
Query: 634 TPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLY 693
TP YMAPE + ++ KV SDVWS G +LY++ G+ P+ F N
Sbjct: 174 TPMYMAPEAM-----------SSQGKVDFKSDVWSLGLVLYELCLGRSPFAAFLDKNATP 222
Query: 694 AIMNPDVK 701
A+++ V+
Sbjct: 223 ALLHTVVQ 230
>YJL095w [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1478
Score = 72.4 bits (176), Expect = 3e-12
Identities = 66/260 (25%), Positives = 121/260 (46%), Gaps = 35/260 (13%)
Query: 495 KVYALKRVSFDEFDE------SSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLM 548
++ A+K+V ++ S+++ + E+ LK L++ +V+ + + + L +
Sbjct: 1199 EMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLN-IVQYLGFENKNNIYSLFL 1257
Query: 549 E-CGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK-G 606
E + ++ + FD +++ +++K + +H I+H D+K N + + G
Sbjct: 1258 EYVAGGSVGSLIRMYGR--FDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDG 1315
Query: 607 MLKIIDFGIANAVPDHTVNIYRDNQI---GTPNYMAPETLVAMNFTRNDGEQAKWKVGKP 663
+ KI DFGI+ D IY ++ + GT +MAPE + G AK
Sbjct: 1316 ICKISDFGISRKSKD----IYSNSDMTMRGTVFWMAPEMV-----DTKQGYSAK------ 1360
Query: 664 SDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTV--IPRTVIDT 721
D+WS GCI+ +M GK P+ + ++ I P PE D+ + I R +D
Sbjct: 1361 VDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPE-DTLPLISQIGRNFLD- 1418
Query: 722 IRSCLERNPISRVTIDQLLS 741
+C E NP R T ++LLS
Sbjct: 1419 --ACFEINPEKRPTANELLS 1436
>SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1401
Score = 72.4 bits (176), Expect = 3e-12
Identities = 74/268 (27%), Positives = 115/268 (42%), Gaps = 46/268 (17%)
Query: 510 SSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFD 568
S++D E+ +L++L N VV + + +++ ME C L+ +L +I D
Sbjct: 1078 STVDQIHNEMTVLERL-NHPNVVTYYGVEVHREKVYIFMEFCQGGSLADLLAH-GRIE-D 1134
Query: 569 TEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFV-KGMLKIIDFGIANAV--PDHTVN 625
++ + ++++ + +H I+H D+KPAN + +GM+K DFG A V P
Sbjct: 1135 ENVLKVYVVQLLEGLAYIHSQHILHRDIKPANILLDHRGMIKYSDFGSALYVSPPTDPEV 1194
Query: 626 IYRDNQ------IGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYG 679
Y D Q GTP YMAPE ++ K G D+WS GC++ +M+ G
Sbjct: 1195 RYEDIQPELQHLAGTPMYMAPEIILGTK---------KGDFGA-MDIWSLGCVILEMMTG 1244
Query: 680 KPPYGTFQGN----NRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVT 735
P+ + A+ P IP EK I D I C ER+P R
Sbjct: 1245 STPWSEMDNEWAIMYHVAAMHTP--SIPQNEK------ISSLARDFIEQCFERDPEQRPR 1296
Query: 736 IDQLLSGALIN-----------PVTVTK 752
LL+ I P T+TK
Sbjct: 1297 AVDLLTHPWITDFRKKTIITMPPATITK 1324
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 72.4 bits (176), Expect = 3e-12
Identities = 81/322 (25%), Positives = 137/322 (42%), Gaps = 51/322 (15%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHD 554
++ A+K+ + D+ EI+LLK+L + + +V L++ + +L+ E +H
Sbjct: 28 RIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH-ENLVNLLEVCKKKKRWYLVFEFVDHT 86
Query: 555 LSQVLTQRSKIP--FDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANF-VFVKGMLKII 611
+L P D + V+ + ++I + H +I+H D+KP N V G++K+
Sbjct: 87 ---ILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLC 143
Query: 612 DFGIAN--AVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
DFG A A P Y + T Y APE LV K GK DVW+
Sbjct: 144 DFGFARTLAAPGEVYTDY----VATRWYRAPELLVG-----------DVKYGKAVDVWAI 188
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAIM----------------NP---DVKIP-YPEKDS 709
GC++ +M G+P + ++LY IM NP V++P E++
Sbjct: 189 GCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIKEREP 248
Query: 710 FGTVIPR---TVIDTIRSCLERNPISRVTIDQLLSGALINPVTVTKFFIHDL----IKNA 762
P+ VID + CL +P R +LL + F +L K+A
Sbjct: 249 LERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQELQLKVQKDA 308
Query: 763 VNYGCDQKHVNNERVEELSEDV 784
N +K N ++ +E + +
Sbjct: 309 RNVSLSKKSQNRKKEKEKDDSL 330
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 72.4 bits (176), Expect = 3e-12
Identities = 55/232 (23%), Positives = 112/232 (47%), Gaps = 25/232 (10%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTEFVRYHF 576
E++ L+ L + Q + +L Y + F++ME C ++ + ++ ++ + R+ F
Sbjct: 57 EMDALRNLSH-QNICRLYHYIETEDKFFIVMEYCSGGEMFDYIVRKERL--EESEARHFF 113
Query: 577 QEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVNIYR-DNQIGT 634
++++ + VH H DLKP N + + + LK+IDFG+ ++ + D G+
Sbjct: 114 RQLVSAIAFVHSQGYAHRDLKPENLLLTEDLHLKLIDFGLCAKTEKGRIDKHNLDTCCGS 173
Query: 635 PNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYA 694
P Y APE + + + N+ +DVWS G +LY ++ G P F+ +N
Sbjct: 174 PAYAAPELIQGLQYKGNE-----------ADVWSMGILLYTLLVGALP---FEDDN--MQ 217
Query: 695 IMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLSGALIN 746
IM ++ + F + + + + +R+ L+ P R+++ +LL +N
Sbjct: 218 IMYKKIQSGCFYEPEFLSPLSKQL---LRAMLQVVPERRISVKKLLEHDWLN 266
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 72.4 bits (176), Expect = 3e-12
Identities = 58/191 (30%), Positives = 95/191 (49%), Gaps = 22/191 (11%)
Query: 498 ALKRVSFDEFD-ESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMEC--GEHD 554
A+K ++ D+ E ++ K EI +++ L +V+L + + +F +ME G
Sbjct: 42 AIKIINKDQVKREGMMEQIKREISIMR-LVRHPNIVELKEVMATKTKIFFIMEYVKGGEL 100
Query: 555 LSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLKIIDF 613
S+++ + K + R +FQ++I V H + H DLKP N V G LK+ DF
Sbjct: 101 FSKIVKGKLK----EDSARKYFQQLISAVDFCHSRGVSHRDLKPENLLVDENGDLKVSDF 156
Query: 614 GIANAVPDHTV-NIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
G+ +A+P+ + + Q GTP Y+APE L + K G D+WSCG I
Sbjct: 157 GL-SALPEQILQDGLLHTQCGTPAYVAPEVL-----------RKKGYDGAKGDIWSCGII 204
Query: 673 LYQMVYGKPPY 683
LY ++ G P+
Sbjct: 205 LYVLLAGFLPF 215
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 72.4 bits (176), Expect = 3e-12
Identities = 60/213 (28%), Positives = 106/213 (49%), Gaps = 24/213 (11%)
Query: 495 KVYALKRVSFDEFDESS-IDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMEC--G 551
++YA+K + D E + + K E ++L K+++ +V+L + L+L+++ G
Sbjct: 158 EIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPF-IVQLKYSFQTKYRLYLVLDFING 216
Query: 552 EHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKI 610
H Q+ Q F + R + E++ V +H+ I+H DLKP N + G + +
Sbjct: 217 GHLFFQLYHQGL---FREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDTDGHVML 273
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
DFG+A ++T + ++ GT YMAPE + R G K +D WS G
Sbjct: 274 TDFGLAKEFEENTRS---NSMCGTTEYMAPEIV------RGKGHD------KAADWWSVG 318
Query: 671 CILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIP 703
+LY+M+ GKPP+ +G + I+ +K+P
Sbjct: 319 ILLYEMLTGKPPFLGSKGKIQ-QKIVKDKIKLP 350
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 72.4 bits (176), Expect = 3e-12
Identities = 53/226 (23%), Positives = 104/226 (45%), Gaps = 28/226 (12%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQ 577
E+E+ +L++ V++L + ++L++E + PF +
Sbjct: 62 EVEIHSRLKHPS-VLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTETEAASILK 120
Query: 578 EMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAV--PDHTVNIYRDNQIGT 634
+++ + +H +I+H D+ +N + + M +KI DFG+A + PD GT
Sbjct: 121 QVVAGLLYLHSHNIMHRDISLSNLLLSREMHVKIADFGLATQLKRPDER----HMTMCGT 176
Query: 635 PNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYA 694
PNY++PE + ++ G P+DVWS GC+LY ++ G+PP+ T + L
Sbjct: 177 PNYISPEVV------------SRTSHGLPADVWSVGCMLYTLLVGRPPFETDAVQSTLNK 224
Query: 695 IMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
++ + +P + D I L++ P R+T++ +L
Sbjct: 225 VVMSEYIMP--------AHLSYEAQDLINKLLKKLPHERITLEAVL 262
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 72.4 bits (176), Expect = 3e-12
Identities = 70/297 (23%), Positives = 129/297 (42%), Gaps = 39/297 (13%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLS 556
A+K + + D++++ E+E++K+L++ ++KL + +++++ E + ++
Sbjct: 168 AIKIIDKSQLDQTNLQKVYREVEIMKRLKHPH-IIKLYQVMETKNMIYIVSEYASQGEIF 226
Query: 557 QVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGI 615
+ + ++ R+ F ++I V+ H IVH DLK N + M +KI DFG
Sbjct: 227 DYIAKYGRM--SESAARFKFWQIISAVEYCHKKGIVHRDLKAENLLLDLNMNIKIADFGF 284
Query: 616 ANAV-PDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILY 674
+N P + + G+P Y APE +T G D+WS G +LY
Sbjct: 285 SNHFKPGELLATW----CGSPPYAAPEVFEGKQYT-----------GPEIDIWSLGVVLY 329
Query: 675 QMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRV 734
+V G P+ + +++ +IP+ + IR L P R
Sbjct: 330 VLVCGALPFDGSTLQSLRDRVLSGRFRIPF--------FMSSECEHLIRRMLVLEPTRRY 381
Query: 735 TIDQLLSGALINPVTVTKFFIHDLIKNAVNYGCDQKHVNNERVEELSEDVWNKLAEF 791
TIDQ+ + P + H LI N G ++ + E SED+ +AE+
Sbjct: 382 TIDQIKRHRWMCP----ELLEHVLIAK-YNLGAER-----QTSVEPSEDILRIMAEY 428
>YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1331
Score = 72.0 bits (175), Expect = 3e-12
Identities = 66/243 (27%), Positives = 107/243 (43%), Gaps = 36/243 (14%)
Query: 516 KGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQVLTQRSKIPFDTEFVRYH 575
K E+ +L+ L N +V+ + + + + ME E L +I + Y
Sbjct: 1081 KEEMTVLEML-NHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYT 1139
Query: 576 FQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGIANAVPDHTVNIYRD----- 629
F E+++ + +H + +VH D+KP N + G++K +DFG A V R+
Sbjct: 1140 F-ELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQD 1198
Query: 630 ---------NQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGK 680
+GTP YMAPET+ G K K+G DVW+ GC++ +M G+
Sbjct: 1199 FGVETKSLNEMMGTPMYMAPETI--------SGSAVKGKLGA-DDVWALGCVVLEMATGR 1249
Query: 681 PPYGTFQGNNRLYAIMNPDV--KIP-YPEKDSFGTVIPRTVIDTIRSCLERNPISRVTID 737
P+ +AIM +IP P +D T R ++ CL ++P R T
Sbjct: 1250 RPWSNLDNE---WAIMYHVAAGRIPQLPNRDEM-TAAGRAFLE---RCLVQDPTMRATAV 1302
Query: 738 QLL 740
+LL
Sbjct: 1303 ELL 1305
>HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1165
Score = 72.0 bits (175), Expect = 3e-12
Identities = 65/257 (25%), Positives = 113/257 (43%), Gaps = 28/257 (10%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGV------LFLLME-C 550
A+K + E +E I K EI +LKK + + + + + L+L+ME C
Sbjct: 52 AIKVMDVTEDEEEEI---KLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFC 108
Query: 551 GEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LK 609
G ++ ++ +++ Y +E+++ + +H ++H D+K N + + +K
Sbjct: 109 GAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVK 168
Query: 610 IIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
++DFG++ A D TV R+ IGTP +MAPE + E SD+WSC
Sbjct: 169 LVDFGVS-AQLDRTVG-RRNTFIGTPYWMAPEVIAC-------DENPDATYDYRSDLWSC 219
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAI-MNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLER 728
G +M G PP L+ I NP ++ + + I CL +
Sbjct: 220 GITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWS-------KKFFSFIEGCLVK 272
Query: 729 NPISRVTIDQLLSGALI 745
N + R + +QLL I
Sbjct: 273 NYMQRPSTEQLLKHPFI 289
>Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 525
Score = 72.0 bits (175), Expect = 3e-12
Identities = 61/227 (26%), Positives = 108/227 (46%), Gaps = 28/227 (12%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTEFVRYHF 576
EI ++K+L+N +V +D ++ LF++ME L+ V+T+ + + D +
Sbjct: 294 EILVMKELKNPN-IVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETACM--DEAQIAAVC 350
Query: 577 QEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIIDFGI-ANAVPDHTVNIYRDNQIGT 634
+E ++ ++ +H ++H D+K N + ++G +K+ DFG A P+ + R +GT
Sbjct: 351 RECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSK---RSTMVGT 407
Query: 635 PNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYA 694
P +MAPE + + G D+WS G + +MV G+PPY LY
Sbjct: 408 PYWMAPEVVTRKAY------------GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYL 455
Query: 695 I-MNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLL 740
I N ++ PEK + D + CLE + R + +LL
Sbjct: 456 IATNGTPELQNPEK------LSPIFRDFLNRCLEMDVEKRGSAKELL 496
>Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1212
Score = 72.0 bits (175), Expect = 3e-12
Identities = 65/257 (25%), Positives = 113/257 (43%), Gaps = 28/257 (10%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGV------LFLLME-C 550
A+K + E +E I K EI +LKK + + + + + L+L+ME C
Sbjct: 52 AIKVMDVTEDEEEEI---KLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFC 108
Query: 551 GEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LK 609
G ++ ++ +++ Y +E+++ + +H ++H D+K N + + +K
Sbjct: 109 GAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVK 168
Query: 610 IIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
++DFG++ A D TV R+ IGTP +MAPE + E SD+WSC
Sbjct: 169 LVDFGVS-AQLDRTVG-RRNTFIGTPYWMAPEVIAC-------DENPDATYDYRSDLWSC 219
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAI-MNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLER 728
G +M G PP L+ I NP ++ + + I CL +
Sbjct: 220 GITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWS-------KKFFSFIEGCLVK 272
Query: 729 NPISRVTIDQLLSGALI 745
N + R + +QLL I
Sbjct: 273 NYMQRPSTEQLLKHPFI 289
>Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1320
Score = 72.0 bits (175), Expect = 3e-12
Identities = 65/257 (25%), Positives = 113/257 (43%), Gaps = 28/257 (10%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGV------LFLLME-C 550
A+K + E +E I K EI +LKK + + + + + L+L+ME C
Sbjct: 52 AIKVMDVTEDEEEEI---KLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFC 108
Query: 551 GEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LK 609
G ++ ++ +++ Y +E+++ + +H ++H D+K N + + +K
Sbjct: 109 GAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVK 168
Query: 610 IIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
++DFG++ A D TV R+ IGTP +MAPE + E SD+WSC
Sbjct: 169 LVDFGVS-AQLDRTVG-RRNTFIGTPYWMAPEVIAC-------DENPDATYDYRSDLWSC 219
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAI-MNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLER 728
G +M G PP L+ I NP ++ + + I CL +
Sbjct: 220 GITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWS-------KKFFSFIEGCLVK 272
Query: 729 NPISRVTIDQLLSGALI 745
N + R + +QLL I
Sbjct: 273 NYMQRPSTEQLLKHPFI 289
>Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1166
Score = 72.0 bits (175), Expect = 3e-12
Identities = 65/257 (25%), Positives = 113/257 (43%), Gaps = 28/257 (10%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGV------LFLLME-C 550
A+K + E +E I K EI +LKK + + + + + L+L+ME C
Sbjct: 52 AIKVMDVTEDEEEEI---KLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFC 108
Query: 551 GEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LK 609
G ++ ++ +++ Y +E+++ + +H ++H D+K N + + +K
Sbjct: 109 GAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVK 168
Query: 610 IIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSC 669
++DFG++ A D TV R+ IGTP +MAPE + E SD+WSC
Sbjct: 169 LVDFGVS-AQLDRTVG-RRNTFIGTPYWMAPEVIAC-------DENPDATYDYRSDLWSC 219
Query: 670 GCILYQMVYGKPPYGTFQGNNRLYAI-MNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLER 728
G +M G PP L+ I NP ++ + + I CL +
Sbjct: 220 GITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWS-------KKFFSFIEGCLVK 272
Query: 729 NPISRVTIDQLLSGALI 745
N + R + +QLL I
Sbjct: 273 NYMQRPSTEQLLKHPFI 289
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 72.0 bits (175), Expect = 3e-12
Identities = 69/272 (25%), Positives = 109/272 (39%), Gaps = 46/272 (16%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGE----- 552
A+K + + + +S+ E+ ++K L N +VKL + + L+L+ME
Sbjct: 83 AIKIIDKTQLNPTSLQKLFREVRIMKIL-NHPNIVKLFEVIETEKTLYLIMEYASGGEVF 141
Query: 553 -----HDLSQVLTQRS------------KIPFDTEFVRYHFQEMIKCVKVVHDADIVHSD 595
H + RS K+ + + F ++ V+ H IVH D
Sbjct: 142 DYLVAHGKMKEKEARSKFRQGCQAGQTIKVQVSFDLLSLMFTFIVSAVQYCHQKRIVHRD 201
Query: 596 LKPANFVFVKGM-LKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGE 654
LK N + M +KI DFG +N + TV D G+P Y APE
Sbjct: 202 LKAENLLLDADMNIKIADFGFSN---EFTVGGKLDTFCGSPPYAAPELF----------- 247
Query: 655 QAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTVI 714
Q K G DVWS G ILY +V G P+ ++ +IP+ ++
Sbjct: 248 QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLL 307
Query: 715 PRTVIDTIRSCLERNPISRVTIDQLLSGALIN 746
R ++ NPI R T++Q++ IN
Sbjct: 308 KRFLV--------LNPIKRGTLEQIMKDRWIN 331
>CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 294
Score = 72.0 bits (175), Expect = 3e-12
Identities = 60/215 (27%), Positives = 105/215 (47%), Gaps = 26/215 (12%)
Query: 498 ALKRVS-FDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEH-DL 555
ALK++ F+ D+ + EI+LLK+L N V++ + L +++E E D+
Sbjct: 50 ALKKIQVFEMVDQKARQDCLKEIDLLKQL-NHVNVIRYYASFIDNNQLNIVLELAEAGDM 108
Query: 556 SQVLTQRSK----IPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPAN-FVFVKGMLKI 610
S+++ K IP T + +F ++ + + +H I+H D+KPAN F+ G++K+
Sbjct: 109 SRMIKHFKKGGRLIPEKT--IWKYFVQLARALAHMHSKRIMHRDIKPANVFITGNGIVKL 166
Query: 611 IDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCG 670
D G+ T + + +GTP YM+PE + + G K SD+WS G
Sbjct: 167 GDLGLGRFFSSKTTAAH--SLVGTPYYMSPERI------QESGYNFK------SDLWSTG 212
Query: 671 CILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYP 705
C+LY+M + P+ + LY++ YP
Sbjct: 213 CLLYEMAALQSPF--YGDKMNLYSLCKKIENCEYP 245
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 72.0 bits (175), Expect = 3e-12
Identities = 62/199 (31%), Positives = 99/199 (49%), Gaps = 23/199 (11%)
Query: 498 ALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHDLSQ 557
A+K++ + DE EI LLK+L++ VV L M + LFL+ E DL +
Sbjct: 49 AMKKIRLESEDEGVPSTAVREISLLKELQHPN-VVGLEAVIMQENRLFLIFEFLSFDLKR 107
Query: 558 VLTQRSK---IPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANF-VFVKGMLKIIDF 613
+ Q K +P +T Y FQ +++ + H ++H DLKP N V G +K+ DF
Sbjct: 108 YMDQLGKDEYLPLET-LKSYTFQ-ILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADF 165
Query: 614 GIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCIL 673
G+A A+ + +Y +++ T Y APE L+ ++ +G D+WS GCI
Sbjct: 166 GLARAI-GIPIRVYT-HEVVTLWYRAPEILMGAQ---------RYSMGV--DMWSIGCIF 212
Query: 674 YQMVYGKPPYGTFQGNNRL 692
+M KP FQG++ +
Sbjct: 213 AEMATKKP---LFQGDSEI 228
>At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 601
Score = 72.0 bits (175), Expect = 3e-12
Identities = 59/238 (24%), Positives = 107/238 (44%), Gaps = 30/238 (12%)
Query: 511 SIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMEC--GEHDLSQVLTQRSKIPFD 568
+I+ + E+++L+ L + D + ++++ME G L ++L++ K +
Sbjct: 192 AIEDVRREVKILRALSGHNNLPHFYDAYEDHDNVYIVMELCEGGELLDRILSRGGK--YT 249
Query: 569 TEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVFVK----GMLKIIDFGIANAV-PDHT 623
E + +++ V H +VH DLKP NF+F LK IDFG+++ V PD
Sbjct: 250 EEDAKTVMIQILNVVAFCHLQGVVHRDLKPENFLFTSKEDTSQLKAIDFGLSDYVRPDER 309
Query: 624 VNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPY 683
+N + +G+ Y+APE L T +D+WS G I+Y ++ G P+
Sbjct: 310 LN----DIVGSAYYVAPEVLHRSYSTE-------------ADIWSVGVIVYILLCGSRPF 352
Query: 684 GTFQGNNRLYAIMNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLS 741
+ A++ D P ++ D ++ L ++P R+T Q LS
Sbjct: 353 WARTESGIFRAVLKADPSFDDPP----WPLLSSEARDFVKRLLNKDPRKRLTAAQALS 406
>At2g46070 [T] KOG0660 Mitogen-activated protein kinase
Length = 406
Score = 72.0 bits (175), Expect = 3e-12
Identities = 64/269 (23%), Positives = 117/269 (42%), Gaps = 58/269 (21%)
Query: 544 LFLLMECGEHDLSQVLTQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF 603
++++ E + DL ++L RS ++ R+ ++++ +K VH A+I+H DL+P+N +
Sbjct: 152 VYIVYELMDTDLQRIL--RSNQTLTSDQCRFLVYQLLRGLKYVHSANILHRDLRPSNVLL 209
Query: 604 -VKGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGK 662
K LKI DFG+A D + + T Y APE L+ + +
Sbjct: 210 NSKNELKIGDFGLARTTSD---TDFMTEYVVTRWYRAPELLLNCS-----------EYTA 255
Query: 663 PSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKIPYPEKDSFGTV--------- 713
D+WS GCIL +++ G+P F G + ++ + + P+ S G +
Sbjct: 256 AIDIWSVGCILGEIMTGQP---LFPGKDYVHQLRLITELVGSPDNSSLGFLRSDNARRYV 312
Query: 714 -----------------IPRTVIDTIRSCLERNPISRVTIDQLLSGALINPVTVTKFFIH 756
+P T ID + L +P R+++D+ L A ++P H
Sbjct: 313 RQLPRYPKQQFAARFPKMPTTAIDLLERMLVFDPNRRISVDEALGHAYLSP-------HH 365
Query: 757 DLIKNAV-----NYGCDQKHVNNERVEEL 780
D+ K V ++ + E ++EL
Sbjct: 366 DVAKEPVCSTPFSFDFEHPSCTEEHIKEL 394
>At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 521
Score = 72.0 bits (175), Expect = 3e-12
Identities = 64/264 (24%), Positives = 117/264 (44%), Gaps = 52/264 (19%)
Query: 495 KVYALKRVSFDEF-DESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGE 552
K +A K +S + + + + EI++++ L + +V+ + + + L+ME C
Sbjct: 97 KRFACKSISKKKLVTKGDKEDMRREIQIMQHLSGQPNIVEFKGAYEDEKAVNLVMELCAG 156
Query: 553 HDLSQVLTQRSKIPFDTEFVRYHFQE---------MIKCVKVVHDADIVHSDLKPANFVF 603
+L FD + H+ E ++ V + H ++H DLKP NF+
Sbjct: 157 GEL-----------FDRILAKGHYSERAAASVCRQIVNVVNICHFMGVMHRDLKPENFLL 205
Query: 604 V----KGMLKIIDFGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWK 659
K ++K DFG++ + + V Y+D +G+ Y+APE L K +
Sbjct: 206 SSKDEKALIKATDFGLSVFIEEGRV--YKDI-VGSAYYVAPEVL-------------KRR 249
Query: 660 VGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAIMNPDVKI---PYPEKDSFGTVIPR 716
GK D+WS G ILY ++ G PP+ AI+ ++ P+P I
Sbjct: 250 YGKEIDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGEIDFESQPWPS-------ISN 302
Query: 717 TVIDTIRSCLERNPISRVTIDQLL 740
+ D +R L ++P R++ ++L
Sbjct: 303 SAKDLVRRMLTQDPKRRISAAEVL 326
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 71.6 bits (174), Expect = 4e-12
Identities = 56/203 (27%), Positives = 97/203 (47%), Gaps = 17/203 (8%)
Query: 495 KVYALKRVSFDEFDESSIDGFKGEIELLKKLENKQRVVKLIDYHMGQGVLFLLMECGEHD 554
++ ALK + D DE + EI L+K+L + ++ L D + L L+ E E D
Sbjct: 27 EIVALKVIRIDA-DEGTPSTAIREISLMKELRHPN-IMSLSDVLQTENKLMLVFEYMEKD 84
Query: 555 LSQVL-TQRSKIPFDTEFVRYHFQEMIKCVKVVHDADIVHSDLKPANFVF-VKGMLKIID 612
L + + T ++ V+ Q+++K + H+ ++H DLKP N + +G LK+ D
Sbjct: 85 LKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHENRVLHRDLKPQNLLINSRGELKLAD 144
Query: 613 FGIANAVPDHTVNIYRDNQIGTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCI 672
FG+A ++ VN + N++ T Y AP+ L+ D+WS GCI
Sbjct: 145 FGLARSI-GIPVNTF-SNEVVTLWYRAPDVLLGSRVYSTS-----------IDIWSVGCI 191
Query: 673 LYQMVYGKPPYGTFQGNNRLYAI 695
+ +M G+P + ++L I
Sbjct: 192 MAEMATGRPLFAGSNNEDQLLKI 214
>Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 71.6 bits (174), Expect = 4e-12
Identities = 64/226 (28%), Positives = 103/226 (45%), Gaps = 27/226 (11%)
Query: 518 EIELLKKLENKQRVVKLIDYHMGQGVLFLLME-CGEHDLSQVLTQRSKIPFDTEFVRYHF 576
EI + + L + Q VV + +F+++E C L + L +R K + E RY+
Sbjct: 101 EISIHRSLAH-QHVVGFHGFFEDNDFVFVVLELCRRRSLLE-LHKRRKALTEPE-ARYYL 157
Query: 577 QEMIKCVKVVHDADIVHSDLKPANFVFVKGM-LKIIDFGIANAVPDHTVNIYRDNQIGTP 635
++++ + +H ++H DLK N + + +KI DFG+A V + GTP
Sbjct: 158 RQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGER--KKTLCGTP 215
Query: 636 NYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGKPPYGTFQGNNRLYAI 695
NY+APE L +K DVWS GCI+Y ++ GKPP+ T I
Sbjct: 216 NYIAPEVL------------SKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRI 263
Query: 696 MNPDVKIPYPEKDSFGTVIPRTVIDTIRSCLERNPISRVTIDQLLS 741
+ IP I I+ L+ +P +R TI++LL+
Sbjct: 264 KKNEYSIP--------KHINPVAASLIQKMLQTDPTARPTINELLN 301
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 71.6 bits (174), Expect = 4e-12
Identities = 53/168 (31%), Positives = 81/168 (47%), Gaps = 28/168 (16%)
Query: 521 LLKKLENKQRVVKLIDYHMGQGVL------FLLMECGEHDLSQVLTQRSKIPFDTEFVRY 574
+L K N + ++ L++ Q L +L+ME + +L QV+ + D E + Y
Sbjct: 75 VLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI----HMELDHERMSY 130
Query: 575 HFQEMIKCVKVVHDADIVHSDLKPANFVFVKG--MLKIIDFGIANAVPDHTVNIYRDNQI 632
+M+ +K +H A I+H DLKP+N V VK LKI+DFG+A N +
Sbjct: 131 LLYQMLCGIKHLHSAGIIHRDLKPSNIV-VKSDCTLKILDFGLARTA---CTNFMMTPYV 186
Query: 633 GTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGK 680
T Y APE ++ M + N D+WS GCI+ +MV K
Sbjct: 187 VTRYYRAPEVILGMGYKEN------------VDIWSVGCIMAEMVLHK 222
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 71.6 bits (174), Expect = 4e-12
Identities = 53/168 (31%), Positives = 81/168 (47%), Gaps = 28/168 (16%)
Query: 521 LLKKLENKQRVVKLIDYHMGQGVL------FLLMECGEHDLSQVLTQRSKIPFDTEFVRY 574
+L K N + ++ L++ Q L +L+ME + +L QV+ + D E + Y
Sbjct: 75 VLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI----HMELDHERMSY 130
Query: 575 HFQEMIKCVKVVHDADIVHSDLKPANFVFVKG--MLKIIDFGIANAVPDHTVNIYRDNQI 632
+M+ +K +H A I+H DLKP+N V VK LKI+DFG+A N +
Sbjct: 131 LLYQMLCGIKHLHSAGIIHRDLKPSNIV-VKSDCTLKILDFGLARTA---CTNFMMTPYV 186
Query: 633 GTPNYMAPETLVAMNFTRNDGEQAKWKVGKPSDVWSCGCILYQMVYGK 680
T Y APE ++ M + N D+WS GCI+ +MV K
Sbjct: 187 VTRYYRAPEVILGMGYKEN------------VDIWSVGCIMAEMVLHK 222
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.132 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,159,746
Number of Sequences: 60738
Number of extensions: 2161129
Number of successful extensions: 8066
Number of sequences better than 1.0e-05: 993
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 988
Number of HSP's that attempted gapping in prelim test: 6496
Number of HSP's gapped (non-prelim): 1130
length of query: 793
length of database: 30,389,216
effective HSP length: 114
effective length of query: 679
effective length of database: 23,465,084
effective search space: 15932792036
effective search space used: 15932792036
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)