ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1014 check: MH U KOG0938 Intracellular trafficking, secretion, and vesicular transport Adaptor complexes medium subunit family
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1014 356316 354892 -475
(475 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL062c [U] KOG0938 Adaptor complexes medium subunit family 441 e-124
CE28642 [U] KOG0938 Adaptor complexes medium subunit family 298 1e-80
Hs14917109 [U] KOG0938 Adaptor complexes medium subunit family 296 3e-80
7300861 [U] KOG0938 Adaptor complexes medium subunit family 296 3e-80
SPAC31A2.09c [U] KOG0938 Adaptor complexes medium subunit family 288 1e-77
At5g46630 [U] KOG0938 Adaptor complexes medium subunit family 260 4e-69
7299202 [U] KOG0937 Adaptor complexes medium subunit family 220 4e-57
CE28050 [U] KOG0937 Adaptor complexes medium subunit family 216 6e-56
Hs9506797 [U] KOG0937 Adaptor complexes medium subunit family 211 1e-54
Hs14210504 [U] KOG0937 Adaptor complexes medium subunit family 211 2e-54
SPBP16F5.07 [U] KOG0937 Adaptor complexes medium subunit family 210 4e-54
At1g10730 [U] KOG0937 Adaptor complexes medium subunit family 203 5e-52
At1g60780 [U] KOG0937 Adaptor complexes medium subunit family 202 1e-51
YPL259c [U] KOG0937 Adaptor complexes medium subunit family 197 4e-50
CE11129 [U] KOG0937 Adaptor complexes medium subunit family 182 1e-45
At4g24550 [U] KOG0937 Adaptor complexes medium subunit family 179 1e-44
Hs5803000 [U] KOG2740 Clathrin-associated protein medium chain 157 4e-38
Hs6912240 [U] KOG2740 Clathrin-associated protein medium chain 155 1e-37
7290785 [U] KOG2740 Clathrin-associated protein medium chain 149 9e-36
Hs14917111 [U] KOG0937 Adaptor complexes medium subunit family 134 4e-31
At1g56590 [U] KOG2740 Clathrin-associated protein medium chain 131 3e-30
CE04654 [U] KOG2740 Clathrin-associated protein medium chain 116 8e-26
YHL019c [U] KOG0937 Adaptor complexes medium subunit family 81 3e-15
HsM14916441 [U] KOG2677 Stoned B synaptic vesicle biogenesis pro... 59 1e-08
Hs21361863 [U] KOG2677 Stoned B synaptic vesicle biogenesis protein 59 1e-08
Hs17461156 [U] KOG0937 Adaptor complexes medium subunit family 58 3e-08
Hs5803153_1 [U] KOG2677 Stoned B synaptic vesicle biogenesis pro... 57 8e-08
7288911 [U] KOG2677 Stoned B synaptic vesicle biogenesis protein 56 1e-07
CE08425 [U] KOG2677 Stoned B synaptic vesicle biogenesis protein 51 4e-06
>YOL062c [U] KOG0938 Adaptor complexes medium subunit family
Length = 491
Score = 441 bits (1135), Expect = e-124
Identities = 221/494 (44%), Positives = 325/494 (65%), Gaps = 22/494 (4%)
Query: 1 MLSAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVINDPHVRSPILTLGSTTFQHVIRE 60
M+S + +Y+++G+L+++K K+ +KRS++D+FR QVIN+ VRSP+LTLGSTTF H+
Sbjct: 1 MISGVLVYSSRGELVLNKFFKNSLKRSISDIFRVQVINNLDVRSPVLTLGSTTFHHIRSR 60
Query: 61 SSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQLMEAFGINDEDVLKDEFMLLYEILELTLE 120
DNL WLV ++RSN +S+ IWE+L+KL +M A+ ++ E+ LK+EFM+++E+L++ L
Sbjct: 61 HGDNL--WLVTITRSNANSAAIWEFLYKLDAVMNAYRLDREEALKEEFMIVHEMLDIMLG 118
Query: 121 -NGIPQTTDLAQIIPRVSRKPIEN-NTISKSPDLDDFLSGSN---------------IXX 163
NGIP T+L +I ++S KP+ N + SPD +D LS S+
Sbjct: 119 GNGIPIDTELNSVIAQMSVKPVRNMGGLLDSPDGNDVLSSSSSPTSSAGELHFPKFLTKR 178
Query: 164 XXXXXXXXXXXXXXXXXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGS 223
+ WRP G+ +KK+EV+L +NE+I ILV +DGSI+KS+VDG+
Sbjct: 179 SSSFLGQGDSTSDFYDNNKITWRPKGIIHKKDEVFLYVNERINILVSRDGSILKSYVDGT 238
Query: 224 VDCVSHLSGMPLCQLGLNDTYSIHG-NEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILE 282
+D +HLSG P+C+ GLND+ + +EK L+ + S D GSV+LE
Sbjct: 239 IDITTHLSGTPICRFGLNDSLGMQSEDEKKWLAQQQRHSGSDFGNKNFIPKAAAGSVLLE 298
Query: 283 DCKFHQCVQLNKYEANHVIQFVPPDGPFQLMQYRVIDNINIPFNVIPEV-EIVKNSTLNY 341
DCKFH+CV L+K+ NH+I+FVPPDG +LM+Y V DNIN+PF V P V +++ ++Y
Sbjct: 299 DCKFHECVSLDKFNRNHIIEFVPPDGSMELMKYHVRDNINLPFKVTPIVTHSTRDNEIDY 358
Query: 342 KVTLRSLFPSNVSAKDVTVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTE 401
++TL+SLFP +SAKDV + IPVPP+T+ C +VS G CK+ E M+W++NKY G TE
Sbjct: 359 RITLKSLFPGKLSAKDVVLHIPVPPSTVDCKISVSNGHCKFVPEENAMIWRFNKYNGLTE 418
Query: 402 NTLSGKVAIPATSHDLSDLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQPVKW 461
NTLS V + + +L +W+RPPIS+ FE++MFSNSGLVVR+ ++ VKW
Sbjct: 419 NTLSA-VTVSTSDTTQLNLQQWTRPPISLEFEVMMFSNSGLVVRYFTISGKDSKHRAVKW 477
Query: 462 IKYISHSGAYEIRY 475
IKYIS +G+YE+RY
Sbjct: 478 IKYISKAGSYEVRY 491
>CE28642 [U] KOG0938 Adaptor complexes medium subunit family
Length = 482
Score = 298 bits (763), Expect = 1e-80
Identities = 163/474 (34%), Positives = 264/474 (55%), Gaps = 44/474 (9%)
Query: 1 MLSAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVIND-PHVRSPILTLGSTTFQHVIR 59
M+ +F+YN KG++LIS++ +D V R+ D FR VI+ VRSP+ + T+F HV R
Sbjct: 1 MIGGLFVYNHKGEVLISRIYRDDVTRNAVDAFRVNVIHARQQVRSPVTNMARTSFFHVKR 60
Query: 60 ESSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQLMEA-FGINDEDVLKDEFMLLYEILELT 118
+ +W+ AV+R NV+++M++E+L + M++ FG +E+ +K+ F+L+YE+L+
Sbjct: 61 GN-----VWICAVTRQNVNAAMVFEFLKRFADTMQSYFGKLNEENVKNNFVLIYELLDEI 115
Query: 119 LENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXXXX 178
L+ G PQ TD + ++++ + ++
Sbjct: 116 LDFGYPQNTDPGVLKTFITQQGVRTADAPVPVTKEE-----------------QSQITSQ 158
Query: 179 XXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQL 238
+ WR G+KY++NE++LD+ E + +L+ + G ++ + V G V S+LSGMP C+
Sbjct: 159 VTGQIGWRREGIKYRRNELFLDVIEYVNLLMNQQGQVLSAHVAGKVAMKSYLSGMPECKF 218
Query: 239 GLNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEAN 298
G+ND +I G K S +V ++DC+FHQCV+L K+E
Sbjct: 219 GINDKITIEGKSKPGSDDPNKASR--------------AAVAIDDCQFHQCVKLTKFETE 264
Query: 299 HVIQFVPPDGPFQLMQYRVIDNINIPFNVIPEVEIVKNSTLNYKVTLRSLFPSNVSAKDV 358
H I F+PPDG ++LM+YR +I +PF VIP V V + + KV ++S F ++ A+ +
Sbjct: 265 HAISFIPPDGEYELMRYRTTKDIQLPFRVIPLVREVSRNKMEVKVVVKSNFKPSLLAQKL 324
Query: 359 TVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAIPATSHDLS 418
V+IP PP T GK KY AGE +VWK + G E+ +S ++ + +T +
Sbjct: 325 EVRIPTPPNTSGVQLICMKGKAKYKAGENAIVWKIKRMAGMKESQISAEIDLLSTGN--V 382
Query: 419 DLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQP---VKWIKYISHSG 469
+ +W+RPP+SM FE V F+ SGL VR+LK EP+LNY +KW++YI SG
Sbjct: 383 EKKKWNRPPVSMNFE-VPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSG 435
>Hs14917109 [U] KOG0938 Adaptor complexes medium subunit family
Length = 435
Score = 296 bits (759), Expect = 3e-80
Identities = 166/479 (34%), Positives = 264/479 (54%), Gaps = 50/479 (10%)
Query: 1 MLSAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVIND-PHVRSPILTLGSTTFQHVIR 59
M+ +FIYN KG++LIS++ +D + R+ D FR VI+ VRSP+ + T+F HV R
Sbjct: 1 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR 60
Query: 60 ESSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQLMEA-FGINDEDVLKDEFMLLYEILELT 118
+ +WL AV++ NV+++M++E+L+K+ +M A FG E+ +K+ F+L+YE+L+
Sbjct: 61 SN-----IWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEI 115
Query: 119 LENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXXXX 178
L+ G PQ ++ + ++++ I++ +K
Sbjct: 116 LDFGYPQNSETGALKTFITQQGIKSQHQTKEEQ---------------------SQITSQ 154
Query: 179 XXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQL 238
+ WR G+KY++NE++LD+ E + +L+ G ++ + V G V S+LSGMP C+
Sbjct: 155 VTGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKF 214
Query: 239 GLNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEAN 298
G+ND I K + S+ ++DC FHQCV+L+K+++
Sbjct: 215 GMNDKIVIEKQGKGTADETSKSGKQ--------------SIAIDDCTFHQCVRLSKFDSE 260
Query: 299 HVIQFVPPDGPFQLMQYRVIDNINIPFNVIPEVEIVKNSTLNYKVTLRSLFPSNVSAKDV 358
I F+PPDG F+LM+YR +I +PF VIP V V + L KV ++S F ++ A+ +
Sbjct: 261 RSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKI 320
Query: 359 TVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAIPATSHDLS 418
V+IP P T GK KY A E +VWK + G E+ +S ++ + T +
Sbjct: 321 EVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPT----N 376
Query: 419 DLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQP---VKWIKYISHSGAYEIR 474
D +W+RPPISM FE V F+ SGL VR+LK EP+LNY +KW++YI SG YE R
Sbjct: 377 DKKKWARPPISMNFE-VPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETR 434
>7300861 [U] KOG0938 Adaptor complexes medium subunit family
Length = 438
Score = 296 bits (759), Expect = 3e-80
Identities = 170/487 (34%), Positives = 270/487 (54%), Gaps = 63/487 (12%)
Query: 1 MLSAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVIND-PHVRSPILTLGSTTFQHVIR 59
M+ +F+YN KG++LIS++ +D + R+ D FR VI+ VRSP+ + T+F H+ R
Sbjct: 1 MIGGLFVYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHIKR 60
Query: 60 ESSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQLMEA-FGINDEDVLKDEFMLLYEILELT 118
+ +WL AV++ NV+++M++E+L K+ ++M++ FG E+ +K+ F+L+YE+L+
Sbjct: 61 AN-----IWLAAVTKQNVNAAMVFEFLLKIIEVMQSYFGKISEENIKNNFVLIYELLDEI 115
Query: 119 LENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXXXX 178
L+ G PQ TD + ++++ I++ T + + ++G
Sbjct: 116 LDFGYPQNTDSGTLKTFITQQGIKSATKEEQMQITSQVTG-------------------- 155
Query: 179 XXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLS-GMPLCQ 237
+ WR G+KY++NE++LD+ E + +L+ G ++ + V G V S+LS GMP C+
Sbjct: 156 ---QIGWRREGIKYRRNELFLDVLEYVNLLMSPQGQVLSAHVAGKVVMKSYLSVGMPECK 212
Query: 238 LGLNDTY-------SIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCV 290
G+ND + GN ++E S V+++DC+FHQCV
Sbjct: 213 FGINDKIVMESKGRGLSGNSEAETS-----------------RSGKPVVVIDDCQFHQCV 255
Query: 291 QLNKYEANHVIQFVPPDGPFQLMQYRVIDNINIPFNVIPEVEIVKNSTLNYKVTLRSLFP 350
+L+K+E H I F+PPDG F+LM+YR +I++PF VIP V V + + KV L+S F
Sbjct: 256 KLSKFETEHSISFIPPDGEFELMRYRTTKDISLPFRVIPLVREVGRTKMEVKVVLKSNFK 315
Query: 351 SNVSAKDVTVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAI 410
++ + + VKIP P T GK KY A E +VWK + G E LS ++ +
Sbjct: 316 PSLLGQKIEVKIPTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIEL 375
Query: 411 PATSHDLSDLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQP---VKWIKYISH 467
T +W+RPPISM FE V F+ SG VR+LK EP+LNY VKW++YI
Sbjct: 376 LET----DTKKKWTRPPISMNFE-VPFAPSGFKVRYLKVFEPKLNYSDHDVVKWVRYIGR 430
Query: 468 SGAYEIR 474
SG YE R
Sbjct: 431 SGLYETR 437
>SPAC31A2.09c [U] KOG0938 Adaptor complexes medium subunit family
Length = 446
Score = 288 bits (737), Expect = 1e-77
Identities = 155/476 (32%), Positives = 263/476 (54%), Gaps = 33/476 (6%)
Query: 1 MLSAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVINDPHVRSPILTLGSTTFQHVIRE 60
M+S +FI+N KGD LI K + +K+S+ ++FR ++ + R PI+++GS+T+ + E
Sbjct: 1 MISGLFIFNLKGDTLICKTFRHDLKKSVTEIFRVAILTNTDYRHPIVSIGSSTYIYTKHE 60
Query: 61 SSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQ-LMEAFGINDEDVLKDEFMLLYEILELTL 119
+++VA+++ N + ++ E+L L Q L FG +E+ +KD ++E+L+ +
Sbjct: 61 D-----LYVVAITKGNPNVMIVLEFLESLIQDLTHYFGKLNENTVKDNVSFIFELLDEMI 115
Query: 120 ENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXXXXX 179
+ GI QTT+ P + + + K G+ +
Sbjct: 116 DYGIIQTTE-----PDALARSVSITAVKKK--------GNALSLKRSHSSQLAHTTSSEI 162
Query: 180 XXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQLG 239
PWR +G+KY+KN +Y+DI E++ +L+ G++++S V G V + LSGMP CQ G
Sbjct: 163 PGSVPWRRAGIKYRKNSIYIDIVERMNLLISSTGNVLRSDVSGVVKMRAMLSGMPECQFG 222
Query: 240 LNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEANH 299
LND K + + + S+ G VILEDC+FHQCV+L ++E H
Sbjct: 223 LND--------KLDFKLKQSESKSKSNNSRNPSSVNGGFVILEDCQFHQCVRLPEFENEH 274
Query: 300 VIQFVPPDGPFQLMQYRVIDNINIPFNVIPEVEIVKNSTLNYKVTLRSLFPSNVSAKDVT 359
I F+PPDG +LM YR +NINIPF ++P VE + + Y++++R+ +P +S+ +
Sbjct: 275 RITFIPPDGEVELMSYRSHENINIPFRIVPIVEQLSKQKIIYRISIRADYPHKLSS-SLN 333
Query: 360 VKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAIPATSHDLSD 419
+IPVP +K + V+ GK Y+ E + WK ++ G TE +V + T++
Sbjct: 334 FRIPVPTNVVKANPRVNRGKAGYEPSENIINWKIPRFLGETELIFYAEVELSNTTNQQI- 392
Query: 420 LLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEP-QLNYQPVKWIKYISHSGAYEIR 474
W++PPIS+ F I+MF++SGL V++L+ EP Y+ +KW++Y + +G EIR
Sbjct: 393 ---WAKPPISLDFNILMFTSSGLHVQYLRVSEPSNSKYKSIKWVRYSTRAGTCEIR 445
>At5g46630 [U] KOG0938 Adaptor complexes medium subunit family
Length = 438
Score = 260 bits (664), Expect = 4e-69
Identities = 155/475 (32%), Positives = 259/475 (53%), Gaps = 46/475 (9%)
Query: 3 SAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVINDPHVRS-PILTLGSTTFQHVIRES 61
SAI+ N +GD+LI++ +D V ++ D FRT ++ + + P+ +G +F ++ R S
Sbjct: 6 SAIYFLNLRGDVLINRTYRDDVGGNMVDAFRTHIMQTKELGNCPVRQIGGCSFVYM-RIS 64
Query: 62 SDNLPMWLVAVSRSNVDSSMIWEYLHKLYQLMEAF--GINDEDVLKDEFMLLYEILELTL 119
+ +++V V SN + + ++++ + L +++ G DED +++ F+L+YE+L+ +
Sbjct: 65 N----VYIVIVVSSNANVACGFKFVVEAVALFKSYFGGAFDEDAIRNNFVLIYELLDEIM 120
Query: 120 ENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXXXXX 179
+ G PQ + ++++ + + SK D
Sbjct: 121 DFGYPQNLSPEILKLYITQEGVRSPFSSKPKDKP------------------VPNATLQV 162
Query: 180 XXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQLG 239
WR GL YKKNEV+LDI E + +L+ G++++ V G V LSGMP +LG
Sbjct: 163 TGAVGWRREGLAYKKNEVFLDIVESVNLLMSSKGNVLRCDVTGKVLMKCFLSGMPDLKLG 222
Query: 240 LNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEANH 299
LND G EK EM S ++ L+D FHQCV L ++ +
Sbjct: 223 LNDKI---GLEKES----EMKSR---------PAKSGKTIELDDVTFHQCVNLTRFNSEK 266
Query: 300 VIQFVPPDGPFQLMQYRVIDNINIPFNVIPEVEIVKNSTLNYKVTLRSLFPSNVSAKDVT 359
+ FVPPDG F+LM+YR+ + +N+PF V+P ++ + + + V ++S+F + + A V
Sbjct: 267 TVSFVPPDGEFELMKYRITEGVNLPFRVLPTIKELGRTRMEVNVKVKSVFGAKMFALGVV 326
Query: 360 VKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAIPATSHDLSD 419
VKIPVP T K +F V+ G+ KY+ C+VWK K+ G TE+TLS ++ + +T + +
Sbjct: 327 VKIPVPKQTAKTNFQVTTGRAKYNPSIDCLVWKIRKFPGQTESTLSAEIELIST---MGE 383
Query: 420 LLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQPVKWIKYISHSGAYEIR 474
W+RPPI M F++ MF+ SGL VR LK E + Y V+W++YI+ +G+YEIR
Sbjct: 384 KKSWTRPPIQMEFQVPMFTASGLRVRFLKVWE-KSGYNTVEWVRYITKAGSYEIR 437
>7299202 [U] KOG0937 Adaptor complexes medium subunit family
Length = 426
Score = 220 bits (560), Expect = 4e-57
Identities = 137/477 (28%), Positives = 245/477 (50%), Gaps = 61/477 (12%)
Query: 3 SAIFIYNAKGDLLISKLIK-DHVKRSLADVFRTQVIN--DPHVRSPILTLGSTTFQHVIR 59
SAIF+ + KG +LIS+ + D++ ++ D F ++ + + +PIL TTF ++
Sbjct: 4 SAIFVLDVKGKVLISRNYRGDNIDMAVIDKFMPLLMEREEEGLITPILQTAETTFAYI-- 61
Query: 60 ESSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQL-MEAFGINDEDVLKDEFMLLYEILELT 118
++NL + NV+ ++++ +LHK+ Q+ +E F +E+ ++D F+++YE+L+
Sbjct: 62 -KTNNLYIVSTTPRNKNVNIALVFVFLHKIAQVFVEYFKELEEESIRDNFVIIYELLDEL 120
Query: 119 LENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXXXX 178
L+ G PQTTD + +++ E + + P + ++ +
Sbjct: 121 LDFGYPQTTDSKILQEYITQ---EGHKLELQPRIPVAVTNA------------------- 158
Query: 179 XXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQL 238
WR G+KY+KNEV+LD+ E + +L +G++++S + G++ +LSGMP +L
Sbjct: 159 ----VSWRSEGIKYRKNEVFLDVIESVNLLANANGNVLRSEIVGAIKMRVYLSGMPELRL 214
Query: 239 GLNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEAN 298
GLND + + VE LED KFHQCV+L+++E +
Sbjct: 215 GLNDKVLFESTGRGKSKSVE----------------------LEDVKFHQCVRLSRFEND 252
Query: 299 HVIQFVPPDGPFQLMQYRVIDNINIPFNVIPEVEIVKNSTLNYKVTLRSLFPSNVSAKDV 358
I F+PPDG F+LM YR+ ++ + +E +S + Y + +S F +A +V
Sbjct: 253 RTISFIPPDGEFELMSYRLNTHVKPLIWIESVIERHAHSRVEYMIKAKSQFKRRSTANNV 312
Query: 359 TVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAIPAT-SHDL 417
+ IPVP F + G CKY + ++W + G E + +P+ S D
Sbjct: 313 EIVIPVPADADSPKFKTTIGSCKYAPEQNAIIWTIKSFPGGKEYLMRAHFGLPSVESEDN 372
Query: 418 SDLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQPVKWIKYISHSGAYEIR 474
++ +PPI + FEI F+ SG+ VR+LK E + YQ + W++YI+ +G Y++R
Sbjct: 373 TE----GKPPIQVRFEIPYFTTSGIQVRYLKIIE-KSGYQALPWVRYITQNGDYQLR 424
>CE28050 [U] KOG0937 Adaptor complexes medium subunit family
Length = 422
Score = 216 bits (550), Expect = 6e-56
Identities = 137/475 (28%), Positives = 237/475 (49%), Gaps = 61/475 (12%)
Query: 3 SAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVINDPHVRS--PILTLGSTTFQHVIRE 60
SA+FI + KG +IS+ + + + D F ++ S P+LT T F +
Sbjct: 4 SAMFILDLKGKTIISRNYRGDIDMTAIDKFIHLLMEKEEEGSAAPVLTYQDTNFVFIKHT 63
Query: 61 SSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQLM-EAFGINDEDVLKDEFMLLYEILELTL 119
+ ++LV+ RSNV+ +MI +L+K ++ E F +E+ ++D F+++YE+L+ +
Sbjct: 64 N-----IYLVSACRSNVNVTMILSFLYKCVEVFSEYFKDVEEESVRDNFVVIYELLDEMM 118
Query: 120 ENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXXXXX 179
+ G PQTT+ + ++++ + + + P
Sbjct: 119 DFGFPQTTESRILQEYITQEGQKLISAPRPP--------------------------MAV 152
Query: 180 XXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQLG 239
WR G+KY+KNEV+LD+ E + +L +G++++S + GSV +L+GMP +LG
Sbjct: 153 TNAVSWRSEGIKYRKNEVFLDVIESVNMLASANGTVLQSEIVGSVKMRVYLTGMPELRLG 212
Query: 240 LNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEANH 299
LND G+ + + VE LED KFHQCV+L++++ +
Sbjct: 213 LNDKVLFEGSGRGKSKSVE----------------------LEDVKFHQCVRLSRFDTDR 250
Query: 300 VIQFVPPDGPFQLMQYRVIDNINIPFNVIPEVEIVKNSTLNYKVTLRSLFPSNVSAKDVT 359
I F+PPDG F+LM YR+ + + +E +S +++ + +S F +A +V
Sbjct: 251 TISFIPPDGAFELMSYRLTTVVKPLIWIETSIERHSHSRVSFIIKAKSQFKRRSTANNVE 310
Query: 360 VKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAIPATSHDLSD 419
+ IPVP F S G KY + VW + G E L+ +++P+ + S+
Sbjct: 311 IIIPVPSDADSPKFKTSIGSVKYTPEQSAFVWTIKNFPGGKEYLLTAHLSLPSVMSEESE 370
Query: 420 LLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQPVKWIKYISHSGAYEIR 474
RPPI + FEI F+ SG+ VR+LK E + YQ + W++YI+ +G YE+R
Sbjct: 371 ----GRPPIKVKFEIPYFTTSGIQVRYLKIIE-KSGYQALPWVRYITQNGEYEMR 420
>Hs9506797 [U] KOG0937 Adaptor complexes medium subunit family
Length = 423
Score = 211 bits (538), Expect = 1e-54
Identities = 139/480 (28%), Positives = 234/480 (47%), Gaps = 70/480 (14%)
Query: 3 SAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVIN--DPHVRSPILTLGSTTFQHVIRE 60
SA+FI + KG LIS+ K V S + F ++ + +P+L+ G F +
Sbjct: 4 SAVFILDVKGKPLISRNYKGDVAMSKIEHFMPLLVQREEEGALAPLLSHGQVHFLWIKHS 63
Query: 61 SSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQLM-EAFGINDEDVLKDEFMLLYEILELTL 119
+ ++LVA + N ++S+++ +L+K ++ E F +E+ ++D F+++YE+L+ +
Sbjct: 64 N-----LYLVATTSKNANASLVYSFLYKTIEVFCEYFKELEEESIRDNFVIVYELLDELM 118
Query: 120 ENGIPQTTD---LAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXX 176
+ G PQTTD L + I + S K +E P + + +S
Sbjct: 119 DFGFPQTTDSKILQEYITQQSNK-LETGKSRVPPTVTNAVS------------------- 158
Query: 177 XXXXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLC 236
WR G+KYKKNEV++D+ E + +LV +GS++ S + G++ LSGMP
Sbjct: 159 --------WRSEGIKYKKNEVFIDVIESVNLLVNANGSVLLSEIVGTIKLKVFLSGMPEL 210
Query: 237 QLGLNDT--YSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNK 294
+LGLND + + G K++ SV LED KFHQCV+L++
Sbjct: 211 RLGLNDRVLFELTGRSKNK------------------------SVELEDVKFHQCVRLSR 246
Query: 295 YEANHVIQFVPPDGPFQLMQYRVIDNINIPFNVIPEVEIVKNSTLNYKVTLRSLFPSNVS 354
++ + I F+PPDG F+LM YR+ + + +E +S + V + F
Sbjct: 247 FDNDRTISFIPPDGDFELMSYRLSTQVKPLIWIESVIEKFSHSRVEIMVKAKGQFKKQSV 306
Query: 355 AKDVTVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAIPATS 414
A V + +PVP F S G KY ++W + G E + +P+
Sbjct: 307 ANGVEISVPVPSDADSPRFKTSVGSAKYVPERNVVIWSIKSFPGGKEYLMRAHFGLPSVE 366
Query: 415 HDLSDLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQPVKWIKYISHSGAYEIR 474
+ + RPPI + FEI F+ SG+ VR++K E + YQ + W++YI+ SG Y++R
Sbjct: 367 KEEVE----GRPPIGVKFEIPYFTVSGIQVRYMKIIE-KSGYQALPWVRYITQSGDYQLR 421
>Hs14210504 [U] KOG0937 Adaptor complexes medium subunit family
Length = 423
Score = 211 bits (537), Expect = 2e-54
Identities = 134/475 (28%), Positives = 233/475 (48%), Gaps = 60/475 (12%)
Query: 3 SAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVIN--DPHVRSPILTLGSTTFQHVIRE 60
SA+++ + KG +LI + + V S + F ++ + + SPIL G F +
Sbjct: 4 SAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHN 63
Query: 61 SSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQLM-EAFGINDEDVLKDEFMLLYEILELTL 119
+ ++LVA S+ N S+++ +L+K+ Q+ E F +E+ ++D F+++YE+L+ +
Sbjct: 64 N-----LYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELM 118
Query: 120 ENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXXXXX 179
+ G PQTTD + ++++ + T + P
Sbjct: 119 DFGYPQTTDSKILQEYITQEGHKLETGAPRPP-------------------------ATV 153
Query: 180 XXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQLG 239
WR G+KY+KNEV+LD+ E + +LV +G++++S + GS+ LSGMP +LG
Sbjct: 154 TNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLG 213
Query: 240 LNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEANH 299
LND + + VE LED KFHQCV+L+++E +
Sbjct: 214 LNDKVLFDNTGRGKSKSVE----------------------LEDVKFHQCVRLSRFENDR 251
Query: 300 VIQFVPPDGPFQLMQYRVIDNINIPFNVIPEVEIVKNSTLNYKVTLRSLFPSNVSAKDVT 359
I F+PPDG F+LM YR+ ++ + +E +S + Y + +S F +A +V
Sbjct: 252 TISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVE 311
Query: 360 VKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAIPATSHDLSD 419
+ IPVP F + G K+ +VW + G E + +P+ + +
Sbjct: 312 IHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKE 371
Query: 420 LLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQPVKWIKYISHSGAYEIR 474
+PPIS+ FEI F+ SG+ VR+LK E + YQ + W++YI+ +G Y++R
Sbjct: 372 ----GKPPISVKFEIPYFTTSGIQVRYLKIIE-KSGYQALPWVRYITQNGDYQLR 421
>SPBP16F5.07 [U] KOG0937 Adaptor complexes medium subunit family
Length = 426
Score = 210 bits (534), Expect = 4e-54
Identities = 132/479 (27%), Positives = 235/479 (48%), Gaps = 59/479 (12%)
Query: 1 MLSAIFIYNAKGDLLISKLIKDHVKRSLADVF---RTQVINDPHVRSPILTLGSTTFQHV 57
M SAIF+ N KG ++IS+ + + S+ + F +++V + +P LT + ++
Sbjct: 1 MASAIFVLNLKGKVIISRDYRADIPMSVVEKFLPLKSEVEEEQGFSTPCLTHEGINYIYI 60
Query: 58 IRESSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQL-MEAFGINDEDVLKDEFMLLYEILE 116
++L+A+S+ N D+ + +L K+ + ++ F E+ ++D F+L+YE+L+
Sbjct: 61 HHND-----VYLLALSKMNSDAMEMLVFLRKMADVFIDYFKELQEESIRDNFVLVYELLD 115
Query: 117 LTLENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXX 176
++ G PQTT+ + +++ +NT+ K ++ +
Sbjct: 116 EIMDFGFPQTTETKILQEYITQT---SNTVKKHAPPPIAMTNA----------------- 155
Query: 177 XXXXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLC 236
WR G+ Y+KNEV+LD+ E + ++ DG++++S + G V +LSGMP
Sbjct: 156 ------ISWRSEGIHYRKNEVFLDVIESVNLIAAADGTVIQSEILGKVRLKCYLSGMPEL 209
Query: 237 QLGLNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYE 296
+LGLND ++ +V +ED KFHQCV+L ++E
Sbjct: 210 RLGLNDKVLFEAAGRT---------------------IKGNTVEMEDVKFHQCVRLARFE 248
Query: 297 ANHVIQFVPPDGPFQLMQYRVIDNINIPFNVIPEVEIVKNSTLNYKVTLRSLFPSNVSAK 356
+ I F+PPDG F LM YR+ N+ V E + S + + V ++ F A
Sbjct: 249 NDRTISFIPPDGEFDLMSYRMSSNVRPLIWVECESIVHSGSRIEFMVKAKAQFKKRCIAN 308
Query: 357 DVTVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAIPATSHD 416
+V + IPVP F S G +Y + MVW K+ G E + ++ +P+ ++
Sbjct: 309 NVQIIIPVPEDADSPRFQTSNGHVQYAPEQAAMVWNIKKFAGGKEFFMRAEMGLPSVKNE 368
Query: 417 LSDLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQPVKWIKYISHSGA-YEIR 474
D+ + P+ + F I F+ SG+ VR+LK EP+LNY + W++Y++ +G Y IR
Sbjct: 369 --DIQVQKKRPVQLKFAIPYFTTSGIQVRYLKITEPKLNYHAMPWVRYVTQNGTEYSIR 425
>At1g10730 [U] KOG0937 Adaptor complexes medium subunit family
Length = 428
Score = 203 bits (516), Expect = 5e-52
Identities = 138/476 (28%), Positives = 230/476 (47%), Gaps = 59/476 (12%)
Query: 3 SAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVIN---DPHVRSPILTLGSTTFQHVIR 59
SA+F+ + KG +L+ + + V + A+ F T++I D P+ T+ V
Sbjct: 6 SALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQH 65
Query: 60 ESSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQLMEA-FGINDEDVLKDEFMLLYEILELT 118
+ ++L+ SR N +++ + +LH++ + + F +E+ L+D F+++YE+L+
Sbjct: 66 SN-----IYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEM 120
Query: 119 LENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXXXX 178
++ G PQ T+ A+I+ + +++ P +
Sbjct: 121 MDFGYPQFTE-ARILSEFIKTDAYRMEVTQRPPM-------------------------A 154
Query: 179 XXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQL 238
WR GLK+KKNEV+LD+ E + ILV +G IV+S V G++ ++LSGMP C+L
Sbjct: 155 VTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKL 214
Query: 239 GLNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEAN 298
GLND + ++ ++ LED KFHQCV+L ++E +
Sbjct: 215 GLNDRILLEAQGRA---------------------IKGKAIDLEDIKFHQCVRLARFEND 253
Query: 299 HVIQFVPPDGPFQLMQYRVIDNINIPFNVIPEVEIVKNSTLNYKVTLRSLFPSNVSAKDV 358
I F+PPDG F LM YR+ + V +E S + V RS F A V
Sbjct: 254 RTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSV 313
Query: 359 TVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAIPATSHDLS 418
+++PVP D S G Y + +VWK + G+ E+TL +P+ + + +
Sbjct: 314 EIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEA 373
Query: 419 DLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQPVKWIKYISHSGAYEIR 474
R + PI + FEI F SG+ VR+LK E + YQ W++YI+ +G YE+R
Sbjct: 374 TPER--KAPIRVKFEIPKFIVSGIQVRYLKIIE-KSGYQAHPWVRYITMAGEYELR 426
>At1g60780 [U] KOG0937 Adaptor complexes medium subunit family
Length = 428
Score = 202 bits (513), Expect = 1e-51
Identities = 133/476 (27%), Positives = 233/476 (48%), Gaps = 59/476 (12%)
Query: 3 SAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVIN---DPHVRSPILTLGSTTFQHVIR 59
SA+F+ + KG +L+ + + V + A+ F T++I D P+ T+ V
Sbjct: 6 SALFLLDIKGRVLVWRDYRGDVSAAQAERFFTKLIEKEGDSQSNDPVAYDNGVTYMFVQH 65
Query: 60 ESSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQLMEA-FGINDEDVLKDEFMLLYEILELT 118
+ ++L+ SR N +++ + +LH++ + + F +E+ L+D F+++YE+L+
Sbjct: 66 SN-----VYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEM 120
Query: 119 LENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXXXX 178
++ G PQ T+ A+I+ + +++ P +
Sbjct: 121 MDFGYPQYTE-ARILSEFIKTDAYRMEVTQRPPM-------------------------A 154
Query: 179 XXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQL 238
WR G++YKKNEV+LD+ E + ILV +G IV+S V G++ ++L+GMP C+L
Sbjct: 155 VTNAVSWRSEGIQYKKNEVFLDVIENVNILVNSNGQIVRSDVVGALKMRTYLTGMPECKL 214
Query: 239 GLNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEAN 298
GLND + ++ ++ LED KFHQCV+L ++E +
Sbjct: 215 GLNDRVLLEAQGRA---------------------TKGKAIDLEDIKFHQCVRLARFEND 253
Query: 299 HVIQFVPPDGPFQLMQYRVIDNINIPFNVIPEVEIVKNSTLNYKVTLRSLFPSNVSAKDV 358
I F+PPDG F LM YR+ + V ++E S + + RS F +A +V
Sbjct: 254 RTISFIPPDGAFDLMTYRLSTQVKPLIWVEAQIESHSRSRVEMLIKARSQFKERSTATNV 313
Query: 359 TVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAIPATSHDLS 418
+++PVP S G Y + +VWK + G+ E L + +P+ + + +
Sbjct: 314 EIELPVPTDASNPTVRTSLGSASYAPEKDALVWKIKSFPGNKEYMLRAEFHLPSITAEEA 373
Query: 419 DLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQPVKWIKYISHSGAYEIR 474
R + PI + FEI F+ SG+ VR+LK E + YQ + W++YI+ +G YE+R
Sbjct: 374 TPER--KAPIRVKFEIPYFTVSGIQVRYLKIIE-KSGYQALPWVRYITMAGEYELR 426
>YPL259c [U] KOG0937 Adaptor complexes medium subunit family
Length = 475
Score = 197 bits (500), Expect = 4e-50
Identities = 136/502 (27%), Positives = 251/502 (49%), Gaps = 57/502 (11%)
Query: 1 MLSAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVINDPHVRSPILT--LGSTTFQHVI 58
M SA++ + G L+S+ +D + S D F +++D +S ++ L +++
Sbjct: 1 MASAVYFCDHNGKPLLSRRYRDDIPLSAIDKFPI-LLSDLEEQSNLIPPCLNHNGLEYLF 59
Query: 59 RESSDNLPMWLVAVSRS-NVDSSMIWEYLHKLYQLMEAF-GINDEDVLKDEFMLLYEILE 116
+ +D +++VA+ S + +++ I+ +LHKL +++ + +E+ ++D F+++YE+L+
Sbjct: 60 IQHND---LYVVAIVTSLSANAAAIFTFLHKLVEVLSDYLKTVEEESIRDNFVIIYELLD 116
Query: 117 LTLENGIPQTTD---LAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXX 173
++ GIPQ T+ L Q I + S K +++ ++ +++
Sbjct: 117 EVMDYGIPQITETKMLKQYITQKSFKLVKSAKKKRNATRPPVALTNSVS----------- 165
Query: 174 XXXXXXXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGM 233
WRP G+ +KKNE +LDI E I +L+ + G +++S + G V S LSGM
Sbjct: 166 -----------WRPEGITHKKNEAFLDIVESINMLMTQKGQVLRSEIIGDVKVNSKLSGM 214
Query: 234 PLCQLGLND--TYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGS--------VILED 283
P +LG+ND +S + ++ + + + + S + LED
Sbjct: 215 PDLKLGINDKGIFSKYLDDDTNIPSASATTSDNNTETDKKPSITSSSATNKKKVNIELED 274
Query: 284 CKFHQCVQLNKYEANHVIQFVPPDGPFQLMQYRVIDNINIPFNVIPEVEIVKNSTLNYKV 343
KFHQCV+L+K+E +I F+PPDG F LM YR+ I V++ NS +
Sbjct: 275 LKFHQCVRLSKFENEKIITFIPPDGKFDLMNYRLSTTIKPLIWCDVNVQVHSNSRIEIHC 334
Query: 344 TLRSLFPSNVSAKDVTVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENT 403
++ +A +V + IPVP F S G KY + ++WK + G E +
Sbjct: 335 KAKAQIKRKSTATNVEILIPVPDDADTPTFKYSHGSLKYVPEKSAILWKIRSFPGGKEYS 394
Query: 404 LSGKVAIPATSHD----------LSDLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQ 453
+S ++ +P+ S++ +++L + P+ + F+I F+ SG+ VR+LK EP+
Sbjct: 395 MSAELGLPSISNNEDGNRTMPKSNAEIL---KGPVQIKFQIPYFTTSGIQVRYLKINEPK 451
Query: 454 LNYQPVKWIKYISHSG-AYEIR 474
L Y+ W++YI+ SG Y IR
Sbjct: 452 LQYKSYPWVRYITQSGDDYTIR 473
>CE11129 [U] KOG0937 Adaptor complexes medium subunit family
Length = 470
Score = 182 bits (461), Expect = 1e-45
Identities = 135/517 (26%), Positives = 230/517 (44%), Gaps = 95/517 (18%)
Query: 2 LSAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVIN--DPHVRSPILTLGSTTFQHVIR 59
+S +FI + KG+++IS+ + V S + F ++ D SP+L ++ ++
Sbjct: 3 ISGLFILDLKGNVVISRNYRGDVDMSCIEKFMPLLVEKEDEGSASPVLVHQGISYTYI-- 60
Query: 60 ESSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQLM-EAFGINDEDVLKDEFMLLYEILELT 118
+ ++LV +S+ N + ++ L+K+ ++ E F +E+ ++D F+++YE+ +
Sbjct: 61 ---KYMNVYLVTISKKNTNVILVLSALYKIVEVFCEYFKTLEEEAVRDNFVIIYELFDEM 117
Query: 119 LENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXXXX 178
L+ G PQTT+ + ++++ T+ + + +S
Sbjct: 118 LDFGYPQTTESKILQEFITQQGNRLETVRPPMAVTNAVS--------------------- 156
Query: 179 XXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQL 238
WR G+KY+KNEV+LD+ E + +L G++++S + GS+ LSGMP +L
Sbjct: 157 ------WRSEGIKYRKNEVFLDVIESVNMLANAQGTVLRSEIVGSIRFRVVLSGMPELRL 210
Query: 239 GLNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEAN 298
GLND + V LED KFHQCV+L+++++
Sbjct: 211 GLNDKVF-----------------FQQSGASSRRGNSGKGVELEDIKFHQCVRLSRFDSE 253
Query: 299 HVIQFVPPDGPFQLMQYRVIDNINIPFNVIPEVEIVKNSTLNYKVTLRSLFPSNVSAKDV 358
I F+PPDG F+LM YR+ + V VE +S + Y V +S F A V
Sbjct: 254 RTISFIPPDGEFELMSYRLTTQVKPLIWVEAAVERHAHSRVEYMVKAKSQFKRQSVANHV 313
Query: 359 TVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTE----------------- 401
V IPVP F G KY +VW + G +
Sbjct: 314 EVIIPVPSDVSAPKFKTGAGTAKYVPELNAIVWSIRSFPGEHQVRNIFKYQLNRNVMHIC 373
Query: 402 --------------------NTLSGKVAIPATSHDL----SDLLRWSRPPISMGFEIVMF 437
T G+ I +S L S+ L RPPI++ FEI +
Sbjct: 374 WKTVQYRKKILSEIFFFYIIFTFGGREYIMRSSFMLPSIGSEELE-GRPPINVKFEIPYY 432
Query: 438 SNSGLVVRHLKCQEPQLNYQPVKWIKYISHSGAYEIR 474
+ SGL VR+LK E + YQ + W++Y++ +G Y++R
Sbjct: 433 TTSGLQVRYLKIIE-KSGYQALPWVRYVTQNGDYQMR 468
>At4g24550 [U] KOG0937 Adaptor complexes medium subunit family
Length = 451
Score = 179 bits (453), Expect = 1e-44
Identities = 124/483 (25%), Positives = 228/483 (46%), Gaps = 43/483 (8%)
Query: 1 MLSAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVI---NDPHVRSP-ILTLGSTTFQH 56
M+S F+ + +GD ++ + + V + + F +V D + +P I + + H
Sbjct: 2 MISQFFVLSQRGDNIVFRDYRAEVPKGSTETFFRKVKFWKEDGNAEAPPIFNVDGVNYFH 61
Query: 57 VIRESSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQLMEAF-GINDEDVLKDEFMLLYEIL 115
V + ++ VA +R NV S++ E L ++ ++++ + G+ +ED + F+L+YE+L
Sbjct: 62 V-----KVVGLYFVATTRVNVSPSLVLELLQRIARVIKDYLGVLNEDSFRKNFVLVYELL 116
Query: 116 ELTLENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXX 175
+ ++ G QTT V + I N I SP + + I
Sbjct: 117 DEVIDFGYVQTTST-----EVLKSYIFNEPIVVSPARLQPIDPAAIFTQGAKRMPGTAVT 171
Query: 176 XXXXXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPL 235
+ P G + + E+++DI EKI++ G I+ S +DG++ S+LSG P
Sbjct: 172 KSVVAND----PGGRR--REEIFVDIIEKISVTFSSSGYILTSEIDGTIQMKSYLSGNPE 225
Query: 236 CQLGLNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKY 295
+L LN+ +I +S YD VIL+DC FH+ V+L+ +
Sbjct: 226 IRLALNEDLNIGRGGRSV---------YDYRSSSGS------GVILDDCNFHESVRLDSF 270
Query: 296 EANHVIQFVPPDGPFQLMQYRVIDNINIPFNVIPEVEIVKNSTLNYKVTLRSLFPSNVSA 355
+++ + VPPDG F +M YR+ PF+V +E + +R+ FPS++ A
Sbjct: 271 DSDRTLSLVPPDGEFPVMNYRMTQEFKPPFHVNTLIEEAGRLKAEVIIKIRAEFPSDIIA 330
Query: 356 KDVTVKIPVPPTTIKCDFNV----SGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAIP 411
+TV++P+P T + F + +G + + K + W K G E+TL K+
Sbjct: 331 NTITVQMPLPNYTSRASFELEPGAAGQRTDFKESNKMLEWNLKKIVGGGEHTLRAKLTF- 389
Query: 412 ATSHDLSDLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQPVKWIKYISHSGAY 471
S + + P+SM F I M++ S L V++L+ + +Y P +W++Y++ + +Y
Sbjct: 390 --SQEFHGNITKEAGPVSMTFTIPMYNVSKLQVKYLQIAKKSSSYNPYRWVRYVTQANSY 447
Query: 472 EIR 474
R
Sbjct: 448 VAR 450
>Hs5803000 [U] KOG2740 Clathrin-associated protein medium chain
Length = 418
Score = 157 bits (396), Expect = 4e-38
Identities = 125/489 (25%), Positives = 219/489 (44%), Gaps = 87/489 (17%)
Query: 1 MLSAIFIYNAKGDLLISKLIKDHVKRSLADVF------RTQVINDPHVRSPILTLGSTTF 54
M+ ++F+ N+ GD+ + K K V RS+ D F T+ N P P++
Sbjct: 1 MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVP----PVIPTPHHYL 56
Query: 55 QHVIRESSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQ-LMEAFGINDEDVLKDEFMLLYE 113
V R ++ VAV ++ V + E+LH++ + FG+ E V+KD +++YE
Sbjct: 57 LSVYRHK-----IFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYE 111
Query: 114 ILELTLENGIPQTTD---LAQII--PRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXX 168
+LE L+NG P T+ L ++I P + R + NTI+ S ++ D L +
Sbjct: 112 VLEEMLDNGFPLATESNILKELIKPPTILRTVV--NTITGSTNVGDQLPTGQLSVV---- 165
Query: 169 XXXXXXXXXXXXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVS 228
PWR +G+KY NE Y D+ E+I ++ K GS + + + G +D
Sbjct: 166 ---------------PWRRTGVKYTNNEAYFDVIEEIDAIIDKSGSTITAEIQGVIDACV 210
Query: 229 HLSGMPLCQLGLNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQ 288
L+GMP +L++ M +L+D FH
Sbjct: 211 KLTGMP------------------DLTLSFMNPR-----------------LLDDVSFHP 235
Query: 289 CVQLNKYEANHVIQFVPPDGPFQLMQYRVI--DNINIPFNVIPEVEIVKNSTL-NYKVTL 345
CV+ ++E+ ++ F+PPDG F+L+ Y V + + IP V + +S+L +++T+
Sbjct: 236 CVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITV 295
Query: 346 RSLFPSNVSAKDVTVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLS 405
+ + VTV +P + S G +D K + W K +L
Sbjct: 296 GPKQTMGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLK 355
Query: 406 GKVAIPATSHDLSDLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQPVKWIKYI 465
G +++ A + + P I++ F+I + SGL V L + Y+P K IKY+
Sbjct: 356 GTMSLQAGASKPDE-----NPTINLQFKIQQLAISGLKVNRLDMYGEK--YKPFKGIKYM 408
Query: 466 SHSGAYEIR 474
+ +G +++R
Sbjct: 409 TKAGKFQVR 417
>Hs6912240 [U] KOG2740 Clathrin-associated protein medium chain
Length = 418
Score = 155 bits (393), Expect = 1e-37
Identities = 122/485 (25%), Positives = 218/485 (44%), Gaps = 79/485 (16%)
Query: 1 MLSAIFIYNAKGDLLISKLIKDHVKRSLADVF--RTQVINDPHVRSPILTLGSTTFQHVI 58
M+ ++F+ N GD+ + K K V +S+ D F + D P++ ST ++I
Sbjct: 1 MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVI---STPHHYLI 57
Query: 59 RESSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQ-LMEAFGINDEDVLKDEFMLLYEILEL 117
D L + V+V ++ V + E+LH++ + FG E +KD +++YE+LE
Sbjct: 58 SIYRDKL--FFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEE 115
Query: 118 TLENGIPQTTD---LAQII--PRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXX 172
L+NG P T+ L ++I P + R + N+I+ S ++ D L +
Sbjct: 116 MLDNGFPLATESNILKELIKPPTILRSVV--NSITGSSNVGDTLPTGQLS---------- 163
Query: 173 XXXXXXXXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSG 232
PWR +G+KY NE Y D+ E+I ++ K GS V + + G +D LSG
Sbjct: 164 ---------NIPWRRAGVKYTNNEAYFDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSG 214
Query: 233 MPLCQLGLNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQL 292
MP +LS+ M +L+D FH C++
Sbjct: 215 MP------------------DLSLSFMNPR-----------------LLDDVSFHPCIRF 239
Query: 293 NKYEANHVIQFVPPDGPFQLMQYRVIDN--INIPFNVIPEVEIVKNSTL-NYKVTLRSLF 349
++E+ V+ F+PPDG F+L+ YRV + IP V + +NS+ + +T+
Sbjct: 240 KRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFKENSSCGRFDITIGPKQ 299
Query: 350 PSNVSAKDVTVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVA 409
+ + +TV + +P + + + G +D K + W K +L G V
Sbjct: 300 NMGKTIEGITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLTWDVGKITPQKLPSLKGLVN 359
Query: 410 IPATSHDLSDLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQPVKWIKYISHSG 469
+ + + + P +++ F+I + SGL V L + Y+P K +KY++ +G
Sbjct: 360 LQSGAPKPEE-----NPSLNIQFKIQQLAISGLKVNRLDMYGEK--YKPFKGVKYVTKAG 412
Query: 470 AYEIR 474
+++R
Sbjct: 413 KFQVR 417
>7290785 [U] KOG2740 Clathrin-associated protein medium chain
Length = 422
Score = 149 bits (376), Expect = 9e-36
Identities = 112/475 (23%), Positives = 208/475 (43%), Gaps = 66/475 (13%)
Query: 1 MLSAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVINDPHVRSPILTLGSTTFQHVIRE 60
M+ ++FI N+ G++ + K + V RS+ + F P+ P++ +T ++I
Sbjct: 1 MIHSLFIVNSGGEVFLEKHWRSVVSRSVCEYFLDAQRAAPYDVPPVI---ATPHYYLITV 57
Query: 61 SSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQ-LMEAFGINDEDVLKDEFMLLYEILELTL 119
D + LVA + V + E+LH++ + FG E V+KD ++++YE+L+ L
Sbjct: 58 QRDTVS--LVAACKQEVPPLFVIEFLHRVVDTFQDYFGDCSESVIKDNYVVVYELLDEML 115
Query: 120 ENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXXXXX 179
+NG P T+ + I+ + + P TI+ + SN+
Sbjct: 116 DNGFPLATE-SNILKELIKPPNILRTIANT-----VTGKSNVSTTLPSGQLSAVR----- 164
Query: 180 XXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQLG 239
WR SG++Y NE Y D+ E++ ++ K GS V + + G +DC LSGMP
Sbjct: 165 -----WRRSGVRYTNNEAYFDVIEEVDAIIDKSGSTVFAEIQGHIDCCIKLSGMP----- 214
Query: 240 LNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEANH 299
+L++ M + +D FH CV+ ++EA
Sbjct: 215 -------------DLTLSFMNPR-----------------LFDDVSFHPCVRYKRWEAER 244
Query: 300 VIQFVPPDGPFQLMQYRVIDN--INIPFNVIPEVEIVKNSTLNYKVTLRSLFPSNVSAKD 357
++ F+PPDG F+LM Y + + IP + I +T+ +
Sbjct: 245 LLSFIPPDGNFRLMSYHISSQSVVAIPIYIRHNFSIKTGEQGRLDLTIGPRNTLGRTVDK 304
Query: 358 VTVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAIPATSHDL 417
V +++ +P + C + GK +D+ K + W + S + G V+I + ++
Sbjct: 305 VKLELTMPRCVLNCLLTPNQGKYTFDSVTKTLSWDVGRIDVSKLPNIRGSVSITPGTTNI 364
Query: 418 SDLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQPVKWIKYISHSGAYE 472
+ P +++ F+I + SGL V L + Y+P K +KY++ +G ++
Sbjct: 365 D-----ANPSVNVQFQISQLAVSGLKVNRLDMYGEK--YKPFKGVKYLTKAGKFQ 412
>Hs14917111 [U] KOG0937 Adaptor complexes medium subunit family
Length = 453
Score = 134 bits (336), Expect = 4e-31
Identities = 118/485 (24%), Positives = 215/485 (44%), Gaps = 44/485 (9%)
Query: 1 MLSAIFIYNAKGDLLISKLIK-DHVKRSLADVFRTQVINDPHVRSPILTLGSTTFQHVIR 59
M+S FI ++KGD LI K + D R +A++F ++ P SP++ IR
Sbjct: 1 MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDESPVVMHHHGRHFIHIR 60
Query: 60 ESSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQLMEAF-GINDEDVLKDEFMLLYEILELT 118
S ++LV + NV + E L +L L+ + G E + L+YE+L+
Sbjct: 61 HSG----LYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEV 116
Query: 119 LENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXXXX 178
L+ G QTT + + + + + S L G+
Sbjct: 117 LDYGYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLS 176
Query: 179 XXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQL 238
+ + +KNEV+LD+ E++++L+ +GS++K V G + S L ++
Sbjct: 177 SRSD--------QSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRI 228
Query: 239 GLNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEAN 298
GL + + + KSEL + +++ FH V L+++E++
Sbjct: 229 GLTEEFCV---GKSEL------------------RGYGPGIRVDEVSFHSSVNLDEFESH 267
Query: 299 HVIQFVPPDGPFQLMQYRVIDNI--NIPFNVIPEVEIVKNS-TLNYKVTLRSLFPSNVSA 355
+++ PP G +M+Y++ D++ +PF + P V+ + S L + LR S A
Sbjct: 268 RILRLQPPQGELTVMRYQLSDDLPSPLPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQA 327
Query: 356 KDVTVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAIPATSH 415
+V + +P+P + +S + K + E + W + +G ++ + ++ +P
Sbjct: 328 LNVRLHLPLPRGVVSLSQELSSPEQKAELAEGALRWDLPRVQGGSQLSGLFQMDVPGPPG 387
Query: 416 DLSDLLRWSRPPISMG-----FEIVMFSNSGLVVRHLKCQ-EPQLNYQPVKWIKYISHSG 469
S L S P+ +G FE+ + SGL VR L+ P N P KW++++SHS
Sbjct: 388 PPSHGLSTSASPLGLGPASLSFELPRHTCSGLQVRFLRLAFRPCGNANPHKWVRHLSHSD 447
Query: 470 AYEIR 474
AY IR
Sbjct: 448 AYVIR 452
>At1g56590 [U] KOG2740 Clathrin-associated protein medium chain
Length = 417
Score = 131 bits (329), Expect = 3e-30
Identities = 123/489 (25%), Positives = 212/489 (43%), Gaps = 88/489 (17%)
Query: 1 MLSAIFIYNAKGDLLISKLIKDH-VKRSLADVFRTQVIN--DPHVRSPILTLGSTTFQHV 57
ML IF+ + G++++ K + H V RS+ F Q I+ D P++ + +
Sbjct: 1 MLQCIFLISDSGEVMLEKQLTGHRVDRSICAWFWDQYISQGDSFKALPVIASPTHYLFQI 60
Query: 58 IRESSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQLMEAF--GINDEDVLKDEFMLLYEIL 115
+R+ + +A S+ + M E+L ++ ++ + G+N ED++KD F+++YE+L
Sbjct: 61 VRDG-----ITFLACSQVEMPPLMAIEFLCRVADVLSEYLGGLN-EDLIKDNFIIVYELL 114
Query: 116 ELTLENGIPQTTD---LAQII--PRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXX 170
+ ++NG P TT+ L ++I P + K + T + S D SG+
Sbjct: 115 DEMIDNGFPLTTEPSILKEMIAPPNLVSKMLSVVTGNASNVSDTLPSGAG---------- 164
Query: 171 XXXXXXXXXXXEC-PWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSH 229
C PWRP+ KY NEVY+D+ E++ +V +DG +VK + G V S
Sbjct: 165 -----------SCVPWRPTDPKYSSNEVYVDLVEEMDAIVNRDGELVKCEIYGEVQMNSQ 213
Query: 230 LSGMPLCQLGLNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQC 289
L+G P L ILED +FH C
Sbjct: 214 LTGFPDLTLSF-----------------------------------ANPSILEDMRFHPC 238
Query: 290 VQLNKYEANHVIQFVPPDGPFQLMQYR-VIDNI-NIPFNVIPEVEIVKNSTLNYKVTLRS 347
V+ +E++ V+ FVPPDG F+LM YR V+ + N P V P++ + T V +
Sbjct: 239 VRYRPWESHQVLSFVPPDGEFKLMSYRCVVKKLKNTPVYVKPQI-TSDSGTCRISVLVGI 297
Query: 348 LFPSNVSAKDVTVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGK 407
+ + +T+ +P D + + G + + C W + LSG
Sbjct: 298 RSDPGKTIESITLSFQLPHCVSSADLSSNHGTVTILSNKTC-TWTIGRIPKDKTPCLSGT 356
Query: 408 VAIPATSHDLSDLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQ--EPQLNYQPVKWIKYI 465
+A+ L P +GF+I+ + SGL + L Q P+L K +
Sbjct: 357 LALEPGLERLHVF-----PTFKLGFKIMGIALSGLRIEKLDLQTIPPRL----YKGFRAQ 407
Query: 466 SHSGAYEIR 474
+ +G +++R
Sbjct: 408 TRAGEFDVR 416
>CE04654 [U] KOG2740 Clathrin-associated protein medium chain
Length = 332
Score = 116 bits (290), Expect = 8e-26
Identities = 92/342 (26%), Positives = 148/342 (42%), Gaps = 61/342 (17%)
Query: 1 MLSAIFIYNAKGDLLISKLIKDHVKRSLADVFRTQVINDPHVRS--PILTLGSTTFQHVI 58
ML+++F N+ GD+L+ K K + RS+ D F H PI+ ST ++I
Sbjct: 1 MLNSLFFVNSSGDVLLEKHWKSVIHRSICDYFFDIQKKSIHPEDVPPII---STPHHYLI 57
Query: 59 RESSDNLPMWLVAVSRSNVDSSMIWEYLHKLYQLM-EAFGINDEDVLKDEFMLLYEILEL 117
+NL +LVAV M+ E+LH++ Q + F + +K+ ++++E+L+
Sbjct: 58 NVYQNNL--FLVAVITVETPPLMVIEFLHRVIQTFTQYFDEFSDSSMKENCVMVFELLDE 115
Query: 118 TLENGIPQTTDLAQIIPRVSRKPIENNTISKSPDLDDFLSGSNIXXXXXXXXXXXXXXXX 177
L+NG P T++ I+ + + P +FL NI
Sbjct: 116 MLDNGFPLVTEM-NILQDLIKPP-------------NFLR--NIANQVTGRTNLSETLPT 159
Query: 178 XXXXECPWRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQ 237
PWR G+KY NE Y D+ E+I ++V K GS V + + G VD LSGMP
Sbjct: 160 GQLSNIPWRRQGVKYTNNEAYFDVIEEIDVIVDKQGSTVFAEIQGYVDVCCKLSGMPDLT 219
Query: 238 LGLNDTYSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEA 297
+ L +L+D FH CV+ ++E
Sbjct: 220 MTL-----------------------------------INPRLLDDVSFHPCVRYKRWEN 244
Query: 298 NHVIQFVPPDGPFQLMQYRVI--DNINIPFNVIPEVEIVKNS 337
V+ FVPPDG F+L+ Y + + + IP V + + N+
Sbjct: 245 EKVLSFVPPDGNFRLLSYHIAAQNMVAIPIYVRQVISLKPNA 286
>YHL019c [U] KOG0937 Adaptor complexes medium subunit family
Length = 605
Score = 81.3 bits (199), Expect = 3e-15
Identities = 86/364 (23%), Positives = 140/364 (37%), Gaps = 114/364 (31%)
Query: 185 WRPSGLKYKKNEVYLDINEKITILVG-KDGSIVKSFVDGSVDCVSHLSGMPLCQLGLNDT 243
WR G+ Y KNE +LD+ E++ L+ + G I K+ + G + C +LSGMP ++ +N
Sbjct: 260 WRTKGIHYAKNEFFLDVIERVQYLMDFEKGVIRKNLIHGEIVCRCYLSGMPKLKISIN-- 317
Query: 244 YSIHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKY-------E 296
I+ ++ + + FHQCV L+ E
Sbjct: 318 -----------KILNRDPQF-----------------MSNSSFHQCVSLDSINTIEKDEE 349
Query: 297 AN-------------HVIQFVPPDGPFQLMQYRVIDNI-NIPFNVIPEVEI---VKNSTL 339
N I+F+PPDG F L QY + ++ + P + + EI +K +
Sbjct: 350 KNSDDDAGLQAATDAREIEFIPPDGEFVLCQYELKRHVKDAPMVRLKDFEIKPKLKKFKI 409
Query: 340 NYKVTLRSLFPSNVSAKDVTVKIPVPPT--TIKCD------FNVSGGKCKYDAGEKCMVW 391
+++ F S + V+IP+ K D F + GK ++ + ++W
Sbjct: 410 QIVTKIQTNFKPTNSTSKLNVRIPLTKVFQEYKIDLSKQIRFKANIGKVVFNLSDDFLLW 469
Query: 392 KYNKYKGSTE----------------NTLSGKVA-IPATSHDLSDLLR------WSRPPI 428
+ KG E NT + VA P + + D L+ + PP+
Sbjct: 470 EIQTMKGHREHSTNKSSQYNSDEDDPNTCASMVAEFPLFNQEEYDRLQEEMKTSMNPPPL 529
Query: 429 SMG----------------------------FEIVMFSNSGLVVRHLKCQEPQLNYQPVK 460
G FEI + SGL V +LK +EPQL YQ
Sbjct: 530 RTGPRLEELYRQVHDQQTSHVTPRDKLVNIDFEIPYCTCSGLKVEYLKVEEPQLQYQSFP 589
Query: 461 WIKY 464
W++Y
Sbjct: 590 WVRY 593
>HsM14916441 [U] KOG2677 Stoned B synaptic vesicle biogenesis protein
Length = 702
Score = 59.3 bits (142), Expect = 1e-08
Identities = 58/228 (25%), Positives = 102/228 (44%), Gaps = 30/228 (13%)
Query: 189 GLKYKKNEVYLDINEKITILVGK-DGSIVKSFVDGSVDCVSHLSGMPLCQLGLNDTYSIH 247
GL Y + E+ +D+ ++ + +V K D I++ V + +S LSG+ C+LGLND +
Sbjct: 360 GLNYLEEEITVDVRDEFSGIVSKGDNQILQHHVLTRIHILSFLSGLAECRLGLNDIL-VK 418
Query: 248 GNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEANHVIQFVPPD 307
GN E++ D + L +C+FH CV + + + VI F P D
Sbjct: 419 GN--------EIVLRQDIMPTTTTKW-----IKLHECRFHGCVDEDVFHNSRVILFNPLD 465
Query: 308 G-PFQLMQYR-VIDNINIPFNVI-------PEVEIVKNSTLNYKVTLRSLFPSNVSAKDV 358
F+LM++R V +PF + EVE+ ++ + + V ++V
Sbjct: 466 ACRFELMRFRTVFAEKTLPFTLRTATSVNGAEVEVQSWLRMSTGFSANRDPLTQVPCENV 525
Query: 359 TVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSG 406
++ PVP +K + + GEK + K N+ ++SG
Sbjct: 526 MIRYPVPSEWVK------NFRRESVLGEKSLKAKVNRGASFGSTSVSG 567
>Hs21361863 [U] KOG2677 Stoned B synaptic vesicle biogenesis protein
Length = 905
Score = 59.3 bits (142), Expect = 1e-08
Identities = 58/228 (25%), Positives = 102/228 (44%), Gaps = 30/228 (13%)
Query: 189 GLKYKKNEVYLDINEKITILVGK-DGSIVKSFVDGSVDCVSHLSGMPLCQLGLNDTYSIH 247
GL Y + E+ +D+ ++ + +V K D I++ V + +S LSG+ C+LGLND +
Sbjct: 563 GLNYLEEEITVDVRDEFSGIVSKGDNQILQHHVLTRIHILSFLSGLAECRLGLNDIL-VK 621
Query: 248 GNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEANHVIQFVPPD 307
GN E++ D + L +C+FH CV + + + VI F P D
Sbjct: 622 GN--------EIVLRQDIMPTTTTKW-----IKLHECRFHGCVDEDVFHNSRVILFNPLD 668
Query: 308 G-PFQLMQYR-VIDNINIPFNVI-------PEVEIVKNSTLNYKVTLRSLFPSNVSAKDV 358
F+LM++R V +PF + EVE+ ++ + + V ++V
Sbjct: 669 ACRFELMRFRTVFAEKTLPFTLRTATSVNGAEVEVQSWLRMSTGFSANRDPLTQVPCENV 728
Query: 359 TVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSG 406
++ PVP +K + + GEK + K N+ ++SG
Sbjct: 729 MIRYPVPSEWVK------NFRRESVLGEKSLKAKVNRGASFGSTSVSG 770
>Hs17461156 [U] KOG0937 Adaptor complexes medium subunit family
Length = 124
Score = 58.2 bits (139), Expect = 3e-08
Identities = 31/76 (40%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
Query: 185 WRPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQLGLNDT- 243
W +KYKKNEV++D+ E +LV GSI+ S + G++ LSGMP +LGLND+
Sbjct: 36 WCSERIKYKKNEVFIDVIESANLLVNAKGSILLSEIFGTIKLKVFLSGMPELRLGLNDSM 95
Query: 244 -YSIHGNEKSELSIVE 258
+ + G K++L +E
Sbjct: 96 LFELTGCHKNKLVKLE 111
>Hs5803153_1 [U] KOG2677 Stoned B synaptic vesicle biogenesis protein
Length = 708
Score = 56.6 bits (135), Expect = 8e-08
Identities = 50/189 (26%), Positives = 91/189 (47%), Gaps = 28/189 (14%)
Query: 192 YKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQLGLNDTYSIHGNEK 251
Y++ E+ L+I + V K+G V+S V + C+ ++G C L LND K
Sbjct: 410 YEEQEISLEIVDNFWGKVTKEGKFVESAVITQIYCLCFVNGNLECFLTLNDLEL----PK 465
Query: 252 SELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEANHVIQFVPPDG-PF 310
+ S E SE + + D FH+CV + ++E + +I+FVP D F
Sbjct: 466 RDESYYEKDSE-------------KKGIDILDYHFHKCVNVQEFEQSRIIKFVPLDACRF 512
Query: 311 QLMQYRVIDN-INIPFNVIPEVEIVKNSTLNYK-------VTLRSLFPSNV-SAKDVTVK 361
+LM+++ + N N+PF+ + V +V+ + + + + RS + ++ S ++ +
Sbjct: 513 ELMRFKTLYNGDNLPFS-LKSVVVVQGAYVELQAFVNMASLAQRSSYAGSLRSCDNIRIH 571
Query: 362 IPVPPTTIK 370
PVP IK
Sbjct: 572 FPVPSQWIK 580
>7288911 [U] KOG2677 Stoned B synaptic vesicle biogenesis protein
Length = 1194
Score = 55.8 bits (133), Expect = 1e-07
Identities = 73/339 (21%), Positives = 130/339 (37%), Gaps = 81/339 (23%)
Query: 186 RPSGLKYKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQLGLNDTYS 245
R L YK EV + ++IT+ +G I+K + ++ L+GMP +LG+ND +
Sbjct: 827 RERALTYKMEEVQVTAVDEITVEQDFEGKILKQIARVRLFFLAFLTGMPTIELGVNDMWR 886
Query: 246 IHGNEKSELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEANHVIQFVP 305
I+ + +E + LE +FH V +YE I+F P
Sbjct: 887 QGKEVVGRHDIIPVATE--------------EWIRLEAVEFHSVVNQKEYERTRTIKFQP 932
Query: 306 PDGPF-QLMQYRV--IDNINIPFNVIPEVEIVKNSTLNYKVTLRS--LFPSNVSAK---- 356
PD + +L+++RV N +P + + N KV LR+ L P S K
Sbjct: 933 PDANYIELLRFRVRPPKNRELPLQLKATWCVSGN-----KVELRADILVPGFTSRKLGQI 987
Query: 357 ---DVTVKIPVP--------------------------------------PTTIKCDFNV 375
DV+V+ P+P T + V
Sbjct: 988 PCEDVSVRFPIPECWIYLFRVEKHFRYGSVKSAHRRTGKIKGIERILGAVDTLQESLIEV 1047
Query: 376 SGGKCKYDAGEKCMVWK--------YNKYKGSTENTLSGKVAIPATSHDLSDLLRWSRPP 427
+ G+ KY+ + +VW+ ++ T + L ++A+ + S+L P
Sbjct: 1048 TSGQAKYEHHHRAIVWRCPRLPKEGQGEFGAYTTHQLVCRMALTSYDQIPSEL----APY 1103
Query: 428 ISMGFEIVMFSNSGLVVRHLKCQEPQLNYQPVKWIKYIS 466
+ F + S VR + Q+ + P K+++Y++
Sbjct: 1104 AFVEFTMPATQVSHTTVRSVSVQDSDGDEPPEKYVRYLA 1142
>CE08425 [U] KOG2677 Stoned B synaptic vesicle biogenesis protein
Length = 1657
Score = 50.8 bits (120), Expect = 4e-06
Identities = 43/190 (22%), Positives = 80/190 (41%), Gaps = 26/190 (13%)
Query: 192 YKKNEVYLDINEKITILVGKDGSIVKSFVDGSVDCVSHLSGMPLCQLGLNDTYSIHGNEK 251
YK++EV + ++ + V K+G + + C++ L+G P+ ++GLND
Sbjct: 1249 YKQDEVQIHCYDEYSAFVDKEGILSDQKARVRLFCLAFLTGSPVLEVGLNDRRRQGKEIV 1308
Query: 252 SELSIVEMMSEYDXXXXXXXXXXXXGSVILEDCKFHQCVQLNKYEANHVIQFVPPDGP-F 310
I+ M +E + E +FH V +++ VI F PPDG F
Sbjct: 1309 RRKDILPMYTE--------------RWIRFEALEFHSIVNKPEFDKEQVIAFSPPDGCFF 1354
Query: 311 QLMQYRV-----------IDNINIPFNVIPEVEIVKNSTLNYKVTLRSLFPSNVSAKDVT 359
++M++RV + +I E+ I + + T S N+ +D+
Sbjct: 1355 EIMRFRVRPPRNREKAMTVKSIMKIAGSKVEIRIEAMAAAQIQRTRGSDERRNIPCEDIA 1414
Query: 360 VKIPVPPTTI 369
++ P+P I
Sbjct: 1415 IRFPIPEAWI 1424
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.137 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,066,634
Number of Sequences: 60738
Number of extensions: 1161494
Number of successful extensions: 2714
Number of sequences better than 1.0e-05: 29
Number of HSP's better than 0.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2564
Number of HSP's gapped (non-prelim): 58
length of query: 475
length of database: 30,389,216
effective HSP length: 110
effective length of query: 365
effective length of database: 23,708,036
effective search space: 8653433140
effective search space used: 8653433140
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)