ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1112 good YU KOG2023 Intracellular trafficking, secretion, and vesicular transport Nuclear transport receptor Karyopherin-beta2/Transportin (importin beta superfamily)
r_klactIII1112 good YU KOG2023 Nuclear structure Nuclear transport receptor Karyopherin-beta2/Transportin (importin beta superfamily)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1112 392168 394819 884
(884 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR017c [YU] KOG2023 Nuclear transport receptor Karyopherin-beta... 879 0.0
SPAC2F3.06c [YU] KOG2023 Nuclear transport receptor Karyopherin-... 403 e-112
7295356 [YU] KOG2023 Nuclear transport receptor Karyopherin-beta... 373 e-103
Hs4504907 [YU] KOG2023 Nuclear transport receptor Karyopherin-be... 365 e-100
Hs7305595 [YU] KOG2023 Nuclear transport receptor Karyopherin-be... 352 1e-96
CE18111 [YU] KOG2023 Nuclear transport receptor Karyopherin-beta... 324 4e-88
7295355 [YU] KOG2023 Nuclear transport receptor Karyopherin-beta... 318 3e-86
At2g16950 [YU] KOG2023 Nuclear transport receptor Karyopherin-be... 277 5e-74
At2g16960 [YU] KOG2023 Nuclear transport receptor Karyopherin-be... 161 4e-39
CE18112 [YU] KOG2023 Nuclear transport receptor Karyopherin-beta... 144 5e-34
Hs19923142 [YU] KOG1241 Karyopherin (importin) beta 1 52 3e-06
At4g27640 [YU] KOG2171 Karyopherin (importin) beta 3 51 9e-06
>YBR017c [YU] KOG2023 Nuclear transport receptor
Karyopherin-beta2/Transportin (importin beta
superfamily)
Length = 918
Score = 879 bits (2272), Expect = 0.0
Identities = 452/899 (50%), Positives = 603/899 (66%), Gaps = 42/899 (4%)
Query: 3 WSPDNEGLTQLCLTLQHAVSTNSDERQQALDALETFKLEPQFANYLCYILLH-------- 54
W P + + QL LQ+ +S N + R A++A+E F+L+P+F NYLCYIL+
Sbjct: 5 WKPAEDYVLQLATLLQNCMSPNPEIRNNAMEAMENFQLQPEFLNYLCYILIEGESDDVLK 64
Query: 55 ----LEEMDQLRGTAGILLKNCILGGNIV------DLGYVKSEIVRGLC-LNNKFIVKIT 103
L+++ R TAG+LLKN +LGGN + DLGYVKS I+ GL NN + +T
Sbjct: 65 QHYSLQDLQNNRATAGMLLKNSMLGGNNLIKSNSHDLGYVKSNIIHGLYNSNNNLVSNVT 124
Query: 104 GIVIAALYSTYYRQHREDPQGLITLAQLIELARDNNEGSLKALSKMMEDGAQFFQLQWSN 163
GIVI L+STYYRQHR+DP GL L QL+EL + NE S+KALSK+MED AQFFQL+WS
Sbjct: 125 GIVITTLFSTYYRQHRDDPTGLQMLYQLLELTSNGNEPSIKALSKIMEDSAQFFQLEWSG 184
Query: 164 NQVPIGELVSLFLTLMVEGK-TPVVRSESINCLNNIIPLQCQELSVNLDTLLTNIFSLAS 222
N P+ L+ F + +PV+RSES+ C+N +IPLQ Q V LD L IF LA
Sbjct: 185 NTKPMEALLDSFFRFISNPNFSPVIRSESVKCINTVIPLQTQSFIVRLDKFLEIIFQLAQ 244
Query: 223 SESSYLVKQQICQCLTLNLEFRPDKLMTHLQGIIQFMGHLIVNTDRNDSEEEKVALGACE 282
++ + LV+ QIC + LEFRPDKL++HL GI+QFM HLI + EEKVA+ ACE
Sbjct: 245 NDENDLVRAQICISFSFLLEFRPDKLVSHLDGIVQFMLHLITTVN-----EEKVAIEACE 299
Query: 283 FILALVSNTNVPDHLIQPYVQELVPLLLTNMVYSQEEIVVMEASNGXXXXXXXXXXXIKP 342
F+ A ++ N+P+H++QPYV+++VP+LL+ MVY++E IV++EASN IKP
Sbjct: 300 FLHAFATSPNIPEHILQPYVKDIVPILLSKMVYNEESIVLLEASNDDDAFLEDKDEDIKP 359
Query: 343 VSAKIQKKXXXXXXXXXXXXXXXX-----------XXWNLRKCAASVLDILTGIFPKEVI 391
++ +I KK WNLRKC+A+ LD++T I P +V+
Sbjct: 360 IAPRIVKKKEAGNGEDADDNEDDDDDDDDEDGDVDTQWNLRKCSAATLDVMTNILPHQVM 419
Query: 392 ETALPLLREHLTSDSWYIREATTLSLGAMAEGGMKYFDGQLPALIPFLVEQLKSPWFPVR 451
+ A P LREHL SD W+IREAT L+LGAMAEGGMKYF+ LPALIPFLVEQL W PVR
Sbjct: 420 DIAFPFLREHLGSDRWFIREATILALGAMAEGGMKYFNDGLPALIPFLVEQLNDKWAPVR 479
Query: 452 RMTCWTLSRFSIWILDDRTEFLMPVLNPIMETLLDKKKGVQEXXXXXXXXFIENSDPDIV 511
+MTCWTLSRFS WIL D TEFL+PVL PI+ TL+DKKK VQE FIEN+D ++V
Sbjct: 480 KMTCWTLSRFSPWILQDHTEFLIPVLEPIINTLMDKKKDVQEAAISSVAVFIENADSELV 539
Query: 512 GTVLYEPLLDRFDECFRFYQKKNLIILYDAVSRLSEKCDLDEQAITKLLPHLLNKWSALD 571
T+ Y LL FD+C ++Y+KKNLIILYDA+ R +EKC LDE A+ +LP L+ KW+ L
Sbjct: 540 ETLFYSQLLTSFDKCLKYYKKKNLIILYDAIGRFAEKCALDETAMQIILPPLIEKWALLS 599
Query: 572 DNDKELWPLLECLSYVSTSLGPRFAPMAMEVYNRAWNILCRCVDLEAKSQVDPTIVVPEK 631
D+DKELWPLLECLS V++SLG RF PMA EVYNRA+ ILC CV+LEAKS DPTIVVPEK
Sbjct: 600 DSDKELWPLLECLSCVASSLGERFMPMAPEVYNRAFRILCHCVELEAKSHQDPTIVVPEK 659
Query: 632 DFIITSLDLIDGLVQGLGYDSKALLFP--NHDTNMFSVILQCLQDHSHEVRQSAYALLGD 689
DFIITSLDLIDGLVQGLG S+ LLFP D + ++L+CLQD HEVRQS +ALLGD
Sbjct: 660 DFIITSLDLIDGLVQGLGAHSQDLLFPQGTKDLTILKIMLECLQDPVHEVRQSCFALLGD 719
Query: 690 IAYYYERQLFTSDFSKRMVETIGNELIQNGENHEAVSTVNNAIWCLGLMAHKIDLGPCII 749
I Y++ +L + + ++ IG E++ N ++ + V NAIW LGL++ +IDL II
Sbjct: 720 IVYFFNSELVIGNL-EDFLKLIGTEIMHN-DDSDGTPAVINAIWALGLISERIDLNTYII 777
Query: 750 EISRIVLDLFCSTQLVLPTSIMENLCITIARLAHFHPEIFTQPPFAGETQWHKWCSIASE 809
++SRI+LDLF + ++ +S+MENL +TI ++ HPE+F+ FA ++ W+KWC +
Sbjct: 778 DMSRIILDLFTTNTQIVDSSVMENLSVTIGKMGLTHPEVFSSGAFANDSNWNKWCLSVNA 837
Query: 810 LTDPEEKTVSYTGFIKIMNLMDFNAQGMPSDKTWELFFRGLQQDVDISIISEDLYALAM 868
L D EEK+ +Y GF+KI+NL + + S+ T GL +V+ ++ ++++Y M
Sbjct: 838 LDDVEEKSSAYMGFLKIINLT--STEVTMSNDTIHKIVTGLSSNVEANVFAQEIYTFLM 894
>SPAC2F3.06c [YU] KOG2023 Nuclear transport receptor
Karyopherin-beta2/Transportin (importin beta
superfamily)
Length = 910
Score = 403 bits (1036), Expect = e-112
Identities = 284/876 (32%), Positives = 448/876 (50%), Gaps = 85/876 (9%)
Query: 2 PWSPDNEGLTQLCLTLQHAVSTNSDERQQALDALETFKLEPQFANYLCYILLHLEEMD-Q 60
PW + L +L +++++S NS R AL+ LE K P NYL IL++ E+
Sbjct: 5 PWVLQEQVLVELSEVIKNSLSENSQTRNAALNLLEKAKDIPDLNNYLTCILINATELSVS 64
Query: 61 LRGTAGILLKNCIL------GGNIVDLGYVKSEIVRGLCLNNKFIVKITGIVIAALYSTY 114
+R AG+LLKN + G + L Y KS ++RGLC + I I+G VI + S +
Sbjct: 65 IRSAAGLLLKNNVRVSSLESGSGLQSLDYTKSTVIRGLCDPEQLIRGISGNVITTIISRW 124
Query: 115 YRQHREDPQGLIT----LAQLIEL----ARDNNEGSLKALSKMMEDGAQFFQLQWSNNQV 166
G+ T L QL+E+ A EG+ AL+K+ ED AQ ++ +
Sbjct: 125 ---------GISTWPEVLPQLMEMLSSPASTTQEGAFSALTKICEDSAQELDRDFNGTR- 174
Query: 167 PIGELVSLFLTLMVEGKTPVVRSESINCLNNIIPLQCQELSVNLDTLLTNIFSLASSESS 226
P+ ++ F+ L + P +R++++ CLN + +Q Q L ++DT L ++LA+ S
Sbjct: 175 PLDFMIPRFIEL-ARHENPKIRTDALFCLNQFVLIQSQSLYAHIDTFLETCYALATDVSP 233
Query: 227 YLVKQQICQCLTLNLEFRPDKLMTHLQGIIQFMGHLIVNTDRNDSEEEKVALGACEFILA 286
V++ +CQ L L+ RPDK+ L I+++M + ++D+N VAL ACEF LA
Sbjct: 234 N-VRKNVCQALVYLLDVRPDKIAPSLGSIVEYMLYSTQDSDQN------VALEACEFWLA 286
Query: 287 LVSNTNVPDHLIQPYVQELVPLLLTNMVYSQEEIVVMEASNGXXXXXXXXXXXIKPVSAK 346
+ ++ L PY+ ++VP+LL MVYS +++++ ++ I+P AK
Sbjct: 287 IAEQPDLCSAL-GPYLDKIVPMLLQGMVYSDMDLLLL-GNDADDYDVEDREEDIRPQHAK 344
Query: 347 IQKKXXXXXXXXXXXXXXXXXX-----------------------WNLRKCAASVLDILT 383
+ + WNLRKC+A+ LD+L+
Sbjct: 345 GKSRITLNTQGPITQQGSSNADADELEDEDEDDDEFDEDDDAFMDWNLRKCSAAALDVLS 404
Query: 384 GIFPKEVIETALPLLREHLTSDSWYIREATTLSLGAMAEGGMKYFDGQLPALIPFLVEQL 443
+ + ++E LP L++ LTS+ W ++EA L++GA+AEG M LP L P+ + L
Sbjct: 405 SFWKQRLLEIILPHLKQSLTSEDWKVQEAGVLAVGAIAEGCMDGMVQYLPELYPYFLSLL 464
Query: 444 KSPWFPVRRMTCWTLSRFSIWIL-----DDRTEFLMPVLNPIMETLLDKKKGVQEXXXXX 498
S VR +TCWTL R+S W +DR ++ +P+L ++ ++D K VQE
Sbjct: 465 DSKKPLVRTITCWTLGRYSKWASCLESEEDRQKYFVPLLQGLLRMVVDNNKKVQEAGCSA 524
Query: 499 XXXFIENSDPDIVGTVLYEPLLDRFDECFRFYQKKNLIILYDAVSRLSEKCDL---DEQA 555
E + P +V + EP+L F+ YQ+KN++ILYDAV L++ D++
Sbjct: 525 FAILEEQAGPSLVPYL--EPILTNLAFAFQKYQRKNVLILYDAVQTLADYVGSALNDKRY 582
Query: 556 ITKLLPHLLNKWSALDDNDKELWPLLECLSYVSTSLGPRFAPMAMEVYNRAWNILCRCVD 615
I L+ LL KWS + D+D L+PL ECLS V+ +L FAP A E Y R + IL +
Sbjct: 583 IELLITPLLQKWSMIPDDDPNLFPLFECLSSVAVALRDGFAPFAAETYARTFRILRNTLY 642
Query: 616 LEAKSQVDPTIVVPEKDFIITSLDLIDGLVQGLGYDSKALLFPNHDTNMFSVILQCLQDH 675
L +Q DPT+ VP++DF++T+LDL+ G++Q LG LL D + +I C +D
Sbjct: 643 LITTAQNDPTVDVPDRDFLVTTLDLVSGIIQALGSQVSPLL-AQADPPLGQIIGICAKDE 701
Query: 676 SHEVRQSAYALLGDIAYYYERQL--FTSDFSKRMVETIGNELIQNGENHEAVSTVNNAIW 733
EVRQSAYALLGD+ Y Q+ + M+ + L+ VS NNAIW
Sbjct: 702 VPEVRQSAYALLGDMCMYCFDQIRPYCDALLVDMLPQMQLPLLH-------VSASNNAIW 754
Query: 734 CLGLMAHKIDLGPCIIEISRIVLD-LFCSTQLVLP-TSIMENLCITIARLAHFHPEIFTQ 791
G MA + LG + + + +L+ L C + T+++EN+ ITI RL ++PE+
Sbjct: 755 SAGEMA--LQLGKDMQQWVKPLLERLICILKSKKSNTTVLENVAITIGRLGVYNPELVAP 812
Query: 792 PPFAGETQWHKWCSIASELTDPEEKTVSYTGFIKIM 827
E + W I + + EEK ++ GF I+
Sbjct: 813 HL---ELFYQPWFEIIKTVGENEEKDSAFRGFCNIL 845
>7295356 [YU] KOG2023 Nuclear transport receptor
Karyopherin-beta2/Transportin (importin beta
superfamily)
Length = 893
Score = 373 bits (957), Expect = e-103
Identities = 273/872 (31%), Positives = 445/872 (50%), Gaps = 70/872 (8%)
Query: 1 MPWSPDNEGLTQLCLTLQHAVSTNSDERQQALDALETFKLEPQFANYLCYILLHLEEMDQ 60
M W P EGL Q+ L+ + S ++ + LE F P F NYL Y+L L+ D+
Sbjct: 1 MTWEPQGEGLQQIIAILKESQSPDTATQMAVQMKLEEFNRYPDFNNYLIYVLTKLKTEDE 60
Query: 61 -LRGTAGILLKNCI------LGGNIVDLGYVKSEIVRGLCLNNKFIVKITGIVIAALYST 113
R +G++LKN I L IV+ Y+K E ++ + + I GI+I + S
Sbjct: 61 PTRSLSGLILKNNIRMHGTTLQPEIVE--YIKHECLQAVGDASPLIRATVGILITTIASN 118
Query: 114 YYRQHREDPQGLITLAQLIELARDNN--EGSLKALSKMMEDGAQFFQLQWSNNQVPIGEL 171
+ PQ L +L ++++ +D N EG+ AL K+ ED A+ N P+ +
Sbjct: 119 GGLHNW--PQLLPSLCEMLD-NQDYNVCEGAFSALQKICEDSAEILDSAALNR--PLNIM 173
Query: 172 VSLFLTLMVEGKTPVVRSESINCLNNIIPLQCQELSVNLDTLLTNIFSLASSESSYLVKQ 231
+ FL + +P +RS +I C+N I + Q L +N+D+ + N+F L+S E + V++
Sbjct: 174 IPKFLEYF-KHSSPKIRSHAIACINQFIINRSQALMLNIDSFIENLFHLSSDED-HEVRK 231
Query: 232 QICQCLTLNLEFRPDKLMTHLQGIIQFMGHLIVNTDRNDSEEEKVALGACEFILALVSNT 291
+C L + LE R D+LM H+ II++M R +E VAL A EF L+L +
Sbjct: 232 NVCHGLVMLLEVRMDRLMPHMSQIIEYM------LLRTQDTDEGVALEASEFWLSLAEQS 285
Query: 292 NVPDHLIQPYVQELVPLLLTNMVYSQEEIVVMEASNGXXXXXXXXXXXIKPVSAKIQKKX 351
D ++ PY+ +L P+L+ M YS+ +I++++ + I+P K +
Sbjct: 286 ICKD-VLAPYLAQLAPVLVRGMRYSEVDIILLKGNVEEDDMVPDREEDIRPRFHKSRAHT 344
Query: 352 XXXXXXXXXXXX---------------XXXXXWNLRKCAASVLDILTGIFPKEVIETALP 396
WNLRKC+A+ LD+L +F ++ + LP
Sbjct: 345 IRSTQEGGAGATGDDDDDEFEDGMDDDSSLSEWNLRKCSAAALDVLANVFREDCLPVVLP 404
Query: 397 LLREHLTSDSWYIREATTLSLGAMAEGGMKYFDGQLPALIPFLVEQLKSPWFPVRRMTCW 456
+L+E L W I+E+ L+LGA+AEG M+ LP LIP+L+ L VR +TCW
Sbjct: 405 ILKETLFHQEWVIKESGVLALGAIAEGCMQGMIQHLPELIPYLISCLSDKKALVRSITCW 464
Query: 457 TLSRFSIWILDD-RTEFLMPVLNPIMETLLDKKKGVQEXXXXXXXXFIENSDPDIVGTVL 515
TLSR++ W+++ ++L P++ +++ +LD K VQE E + ++V +
Sbjct: 465 TLSRYANWVVNQPHDQYLKPLMEELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLE 524
Query: 516 YEPLLDRFDECFRFYQKKNLIILYDAVSRLSEKCD---LDEQAITKLLPHLLNKWSALDD 572
Y +L F YQ KNL+ILYDAV L++ Q I L+P L++KW+ L D
Sbjct: 525 Y--ILKTLVFAFSKYQHKNLLILYDAVGTLADSVGHHLNKPQYIDILMPPLIDKWNLLKD 582
Query: 573 NDKELWPLLECLSYVSTSLGPRFAPMAMEVYNRAWNILCRCVDLEAKSQVDPTIVVPEKD 632
+DK+L+PLLECLS ++T+L F P VY R +++ + ++ E + + T P+K+
Sbjct: 583 DDKDLFPLLECLSSIATALQSGFLPYCDPVYRRCISLIEQTINQEMLCKQNQTYDHPDKE 642
Query: 633 FIITSLDLIDGLVQGLGYDSKALLFPNHDTNMFSVILQCLQDHSHEVRQSAYALLGDI-- 690
+I +LDL+ GL +GL + L+ ++N+ ++ QC+QD EVRQS++ALLGD+
Sbjct: 643 RMIVALDLLSGLAEGLDRHIETLV---ANSNIMHLLYQCMQDVLPEVRQSSFALLGDLTK 699
Query: 691 AYYYERQLFTSDFSKRMVETIGNELIQNGENHEAVSTVNNAIWCLGLMAHKIDLGPCIIE 750
A + F +DF +G L N + +S NNA W +G + K LG +
Sbjct: 700 ACFPHVHPFMADF----FPILGQNL-----NPDFISVCNNATWAIGEICMK--LGEETKQ 748
Query: 751 ISRIVL-DLF-CSTQLVLPTSIMENLCITIARLAHFHPEIFTQPPFAGETQWHKWCSIAS 808
R+VL DLF + P +++EN ITI RL + P P+ E +WC+
Sbjct: 749 YIRLVLSDLFIIINRPNTPKTLLENTAITIGRLGYVCP--VEVAPYLPEFV-RQWCTSLR 805
Query: 809 ELTDPEEKTVSYTGFIKIMNLMDFNAQGMPSD 840
+ D +EK ++ G + +++ N G+ +D
Sbjct: 806 HIRDNDEKDSAFRG---MCHMITVNPAGVVAD 834
>Hs4504907 [YU] KOG2023 Nuclear transport receptor
Karyopherin-beta2/Transportin (importin beta
superfamily)
Length = 890
Score = 365 bits (938), Expect = e-100
Identities = 259/864 (29%), Positives = 434/864 (49%), Gaps = 63/864 (7%)
Query: 3 WSPDNEGLTQLCLTLQHAVSTNSDERQQALDALETFKLEPQFANYLCYILLHLEEMDQ-L 61
W PD +GL Q+ L+ + S ++ ++ LE P F NYL ++L L+ D+
Sbjct: 5 WKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEPT 64
Query: 62 RGTAGILLKNCILG------GNIVDLGYVKSEIVRGLCLNNKFIVKITGIVIAALYSTYY 115
R +G++LKN + + D ++KSE + + ++ I GI+I + S
Sbjct: 65 RSLSGLILKNNVKAHFQNFPNGVTD--FIKSECLNNIGDSSPLIRATVGILITTIASKGE 122
Query: 116 RQHREDPQGLITLAQLIELARDNN-EGSLKALSKMMEDGAQFFQLQWSNNQVPIGELVSL 174
Q+ P L L L++ N EG+ AL K+ ED A+ + P+ ++
Sbjct: 123 LQNW--PDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDR--PLNIMIPK 178
Query: 175 FLTLMVEGKTPVVRSESINCLNNIIPLQCQELSVNLDTLLTNIFSLASSESSYLVKQQIC 234
FL + +P +RS ++ C+N I + Q L +++D+ N+F+LA E V++ +C
Sbjct: 179 FLQFF-KHSSPKIRSHAVACVNQFIISRTQALMLHIDSFTENLFALAGDEEPE-VRKNVC 236
Query: 235 QCLTLNLEFRPDKLMTHLQGIIQFMGHLIVNTDRNDSEEEKVALGACEFILALVSNTNVP 294
+ L + LE R D+L+ H+ I+++M R ++E VAL ACEF L L
Sbjct: 237 RALVMLLEVRMDRLLPHMHNIVEYM------LQRTQDQDENVALEACEFWLTLAEQPICK 290
Query: 295 DHLIQPYVQELVPLLLTNMVYSQEEIVVMEASNGXXXXXXXXXXXIKPVSAKIQKKXXXX 354
D L++ ++ +L+P+L+ M YS +I++++ I+P + +
Sbjct: 291 DVLVR-HLPKLIPVLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQH 349
Query: 355 XXXXXXXXXX---------XXXXWNLRKCAASVLDILTGIFPKEVIETALPLLREHLTSD 405
WNLRKC+A+ LD+L ++ E++ LPLL+E L
Sbjct: 350 DEDGIEEEDDDDDEIDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHH 409
Query: 406 SWYIREATTLSLGAMAEGGMKYFDGQLPALIPFLVEQLKSPWFPVRRMTCWTLSRFSIWI 465
W ++E+ L LGA+AEG M+ LP LIP L++ L VR +TCWTLSR++ W+
Sbjct: 410 EWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWV 469
Query: 466 LDDRTE-FLMPVLNPIMETLLDKKKGVQEXXXXXXXXFIENSDPDIVGTVLYEPLLDRFD 524
+ + +L P++ +++ +LD K VQE E + ++V + Y +LD
Sbjct: 470 VSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAY--ILDTLV 527
Query: 525 ECFRFYQKKNLIILYDAVSRLSEKCD---LDEQAITKLLPHLLNKWSALDDNDKELWPLL 581
F YQ KNL+ILYDA+ L++ + I L+P L+ KW+ L D DK+L+PLL
Sbjct: 528 FAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLL 587
Query: 582 ECLSYVSTSLGPRFAPMAMEVYNRAWNILCRCVDLEAKSQVDP-TIVVPEKDFIITSLDL 640
ECLS V+T+L F P VY R N++ + + + P P+KDF+I +LDL
Sbjct: 588 ECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLNNAQPDQYEAPDKDFMIVALDL 647
Query: 641 IDGLVQGLGYDSKALLFPNHDTNMFSVILQCLQDHSHEVRQSAYALLGDI--AYYYERQL 698
+ GL +GLG + + L+ +N+ +++ QC+QD EVRQS++ALLGD+ A + +
Sbjct: 648 LSGLAEGLGGNIEQLV---ARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKP 704
Query: 699 FTSDFSKRMVETIGNELIQNGENHEAVSTVNNAIWCLGLMAHK--IDLGPCIIEISRIVL 756
+DF + +G L N E +S NNA W +G ++ + I++ P I + ++
Sbjct: 705 CIADF----MPILGTNL-----NPEFISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLV 755
Query: 757 DLFCSTQLVLPTSIMENLCITIARLAHFHPEIFTQPPFAGETQWHKWCSIASELTDPEEK 816
++ + P +++EN ITI RL + P+ P + WC+ + D EEK
Sbjct: 756 EII--NRPNTPKTLLENTAITIGRLGYVCPQ--EVAPML-QQFIRPWCTSLRNIRDNEEK 810
Query: 817 TVSYTGFIKIMNLMDFNAQGMPSD 840
++ G I ++ N G+ D
Sbjct: 811 DSAFRG---ICTMISVNPSGVIQD 831
>Hs7305595 [YU] KOG2023 Nuclear transport receptor
Karyopherin-beta2/Transportin (importin beta
superfamily)
Length = 887
Score = 352 bits (904), Expect = 1e-96
Identities = 267/871 (30%), Positives = 419/871 (47%), Gaps = 74/871 (8%)
Query: 1 MPWSPDNEGLTQLCLTLQHAVSTNSDERQQALDALETFKLEPQFANYLCYILLHLEEMDQ 60
M W PD +GL Q+ L+ + S N+ + D L+ P F NYL ++L L+ D+
Sbjct: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATHRIVRDKLKQLNQFPDFNNYLIFVLTRLKSEDE 60
Query: 61 -LRGTAGILLKNCILGGNIVDLGYVKSEIVRGLCLNN-----KFIVKITGIVIAALYSTY 114
R +G++LKN + + ++ ++ CLNN I GI+I + S
Sbjct: 61 PTRSLSGLILKNNVKA-HYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKG 119
Query: 115 YRQHREDPQGLITLAQLIELARDNN-EGSLKALSKMMEDGAQFFQLQWSNNQVPIGELVS 173
Q P+ L L L+ N EG+ AL K+ ED ++ N P+ ++
Sbjct: 120 ELQMW--PELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNR--PLNIMIP 175
Query: 174 LFLTLMVEGKTPVVRSESINCLNNIIPLQCQELSVNLDTLLTNIFSLASSESSYLVKQQI 233
FL + +P +RS +I C+N I + Q L N+DT + ++F+LA + V++ +
Sbjct: 176 KFLQFF-KHCSPKIRSHAIGCVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPE-VRKNV 233
Query: 234 CQCLTLNLEFRPDKLMTHLQGIIQFMGHLIVNTDRNDSEEEKVALGACEFILALVSNTNV 293
C+ L + LE R D+L+ H+ IIQ+M R +E VAL ACEF L L
Sbjct: 234 CRALVMLLEVRIDRLIPHMHSIIQYM------LQRTQDHDENVALEACEFWLTLAEQPIC 287
Query: 294 PDHLIQPYVQELVPLLLTNMVYSQEEIVVMEASNGXXXXXXXXXXXIKPVSAKIQ----- 348
+ L VQ L+P+L+ M YS+ +I++++ IKP K +
Sbjct: 288 KEVLASHLVQ-LIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLP 346
Query: 349 ---KKXXXXXXXXXXXXXXXXXXWNLRKCAASVLDILTGIFPKEVIETALPLLREHLTSD 405
++ WNLRKC+A+ LD+L +F +E++ LPLL+ L
Sbjct: 347 HEAERPDGSEDAEDDDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHP 406
Query: 406 SWYIREATTLSLGAMAEGGMKYFDGQLPALIPFLVEQLKSPWFPVRRMTCWTLSRFSIWI 465
W ++E+ L LGA+AEG M+ LP LIP L++ L VR + CWTLSR++ W+
Sbjct: 407 EWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWV 466
Query: 466 LDDRTEF-LMPVLNPIMETLLDKKKGVQEXXXXXXXXFIENSDPDIVGTVLYEPLLDRFD 524
+ + L P++ +++ +LD K VQE E + ++V + Y +LD
Sbjct: 467 VSQPPDMHLKPLMTELLKRILDGNKKVQEAACIAFATLEEKACTELVPYLSY--ILDTLV 524
Query: 525 ECFRFYQKKNLIILYDAVSRLSEKCD---LDEQAITKLLPHLLNKWSALDDNDKELWPLL 581
F YQ KNL+ILYDA+ L++ + I KL+P L+ KW+ L D DK+L+PLL
Sbjct: 525 FAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLL 584
Query: 582 ECLSYVSTSLGPRFAPMAMEVYNRAWNILCRCVDLEAK--------SQVDPTIVVPEKDF 633
ECLS V+T+L F P VY C CV L K +Q P+KDF
Sbjct: 585 ECLSSVATALQSGFLPYCEPVYQ------C-CVTLVQKTLAQAMMYTQHPEQYEAPDKDF 637
Query: 634 IITSLDLIDGLVQGLGYDSKALLFPNHDTNMFSVILQCLQDHSHEVRQSAYALLGDIAYY 693
+I +LDL GL +GLG + L+ +N+ +++ QC+QD EVRQS++A LGD
Sbjct: 638 MIVALDLFSGLAEGLGGHVEQLV---ARSNIMTLLFQCMQDSMPEVRQSSFAFLGD---- 690
Query: 694 YERQLFTSDFSKRMVETIGN--ELIQNGENHEAVSTVNNAIWCLG--LMAHKIDLGPCII 749
FT S + I ++ N E +S NNA W +G M ++ P +
Sbjct: 691 -----FTKACSSHVKPCIAEFMPILGTNLNPEFISVCNNATWAIGEICMQMGAEMQPYVQ 745
Query: 750 EISRIVLDLFCSTQLVLPTSIMENLCITIARLAHFHPEIFTQPPFAGETQWHKWCSIASE 809
+ ++++ + P +++EN ITI RL + P+ P + WC+
Sbjct: 746 MVLNNLVEII--NRPNTPKTLLENTAITIGRLGYVCPQ--EVAPML-QQFIRPWCTSLRN 800
Query: 810 LTDPEEKTVSYTGFIKIMNLMDFNAQGMPSD 840
+ D EEK ++ G I ++ N G+ D
Sbjct: 801 IRDNEEKDSAFRG---ICMMIGVNPGGVVQD 828
>CE18111 [YU] KOG2023 Nuclear transport receptor
Karyopherin-beta2/Transportin (importin beta
superfamily)
Length = 883
Score = 324 bits (830), Expect = 4e-88
Identities = 253/872 (29%), Positives = 421/872 (48%), Gaps = 80/872 (9%)
Query: 1 MPWSPDNEGLTQLCLTLQHAVSTNSDERQQALDALETFKLEPQFANYLCYILLHLEEMDQ 60
M + PD L Q+ LQHA ST+ D ++ L +F YL YIL ++EM
Sbjct: 1 MAFQPDQHELEQVIQLLQHAHSTDRDVQRNVQVQLVQLNEHQKFCCYLVYILSDMKEMID 60
Query: 61 L--RGTAGILLKNCILGGNIVDLGYVKSEIVRGLCLNN-----KFIVKITGIVIAALYST 113
R AG+LLKN I VK VR CL + I GI++ +
Sbjct: 61 ATSRSLAGLLLKNNIRAKWNKYPQDVKF-FVRTTCLKSIGDQEPLIRATVGIIVTTIVME 119
Query: 114 YYRQHREDPQGLITLAQLIELARD-NNEGSLKALSKMMEDGAQFFQLQWSNNQVPIGELV 172
+ P L TLA ++ + EG+L AL K+ ED A ++ ++ +P
Sbjct: 120 --ENMCDWPDLLDTLATVLMQPDELMQEGALGALQKVFEDSADRYESEFLRPIMPK---- 173
Query: 173 SLFLTLMVEGKTPVVRSESINCLNNIIPLQCQELSVNLDTLLTNIFSLASSESSYLVKQQ 232
L + E +R+ ++NC+N I+ + + +D LT++F+ +++ V++Q
Sbjct: 174 ---LLVFYEHHAAKMRALAMNCVNCILMVNNDPIDFAIDQFLTSLFA-RHNDNDEEVQKQ 229
Query: 233 ICQCLTLNLEFRPDKLMTHLQGIIQFMGHLIVNTDRNDSEEEKVALGACEFILALVSNTN 292
+C+ LTL L+ +K+M HL +I+++ + E +AL ACEF L++ N++
Sbjct: 230 LCRSLTLLLDTHIEKMMPHLPNVIEYI------IKKTQDHNESIALEACEFWLSIAENSD 283
Query: 293 VPDHLIQPYVQELVPLLLTNMVYSQEEIVVMEASNGXXXXXXXXXXXIKPVSAKIQKKXX 352
+ ++ P++ +L+P+LL +M YS+ + + +N IKP K ++
Sbjct: 284 ICRTMVLPHLDKLIPVLLGSMRYSETDPALK--ANDEDSSVPDREEDIKPRFHKSKQHGL 341
Query: 353 XXXXXXXXXXXXXXXX-----WNLRKCAASVLDILTGIFPKEVIETALPLLREHLTSDSW 407
WN+R+C+A+ LD+L IF K++++ PLL++ L +D+W
Sbjct: 342 GGLVESDDEEDEDDDDDGGGDWNIRRCSAASLDVLASIFGKDLLDKLFPLLKDTLMNDNW 401
Query: 408 YIREATTLSLGAMAEGGMKYFDGQLPALIPFLVEQLKSPWFPVRRMTCWTLSRFSIWILD 467
++E+ L+LGA+AEG M L LIPF++ + VR +TCWTLSR+S I
Sbjct: 402 LVKESGILALGAIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHIAS 461
Query: 468 D---RTEFLMPVLNPIMETLLDKKKGVQEXXXXXXXXFIENSDPDIVGTVLYEPLLDRFD 524
D R +F VL ++ LD K VQE E + ++ +LD+
Sbjct: 462 DENFRQQFFKDVLANLLRCSLDGNKKVQEAACSAFATLEEEAGEQLI--PFLGEILDQLV 519
Query: 525 ECFRFYQKKNLIILYDAVSRLSEKCD---LDEQAITKLLPHLLNKWSALDDNDKELWPLL 581
+ F+ YQ KNL+ILYDA+ L+ + L+P L+ KW L D DKEL+PLL
Sbjct: 520 KAFQCYQAKNLLILYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLL 579
Query: 582 ECLSYVSTSLGPRFAPMAMEVYNRAWNILCRCVDLEAKSQVDP-TIVVPEKDFIITSLDL 640
EC+S + +++G F P V+ R +++ +CV + + P + PE DFII +LDL
Sbjct: 580 ECISAIVSAMGQSFLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDL 639
Query: 641 IDGLVQGLGYDSKALLFPNHDTNMFSVILQCLQDHSHEVRQSAYALLGDIAYYYERQLFT 700
+ GL + L L+ ++ + ++L C D + +VRQS +ALLGD+ T
Sbjct: 640 LSGLAESLPEHMDPLV---ANSKLVELMLFCSLDVTPDVRQSCFALLGDL---------T 687
Query: 701 SDFSKRMVETIGNELIQNGENHE--AVSTVNNAIWCLGLMAHKIDLGPCIIEISRIVLD- 757
+R++ N + +N + +S NNAIW LG +A K +GP + + +++
Sbjct: 688 KACPERVLPQSSNFIFFLAQNLDPSKISVCNNAIWALGELALK--MGPAMKQFIGPIIEP 745
Query: 758 --LFCSTQLVLPTSIMENLCITIARLAHF-------HPEIFTQPPFAGETQWHKWCSIAS 808
+ ++Q + +++EN ITI RL H F +P C
Sbjct: 746 LIVVINSQQNMQRTLLENTAITIGRLGQCCGEELAPHISRFVRP----------CCYSLR 795
Query: 809 ELTDPEEKTVSYTGFIKIMNLMDFNAQGMPSD 840
+ D EK + FI + N+++ N G+ +D
Sbjct: 796 NIKDNAEKE---SAFIGLCNMINMNPVGVLND 824
>7295355 [YU] KOG2023 Nuclear transport receptor
Karyopherin-beta2/Transportin (importin beta
superfamily)
Length = 884
Score = 318 bits (814), Expect = 3e-86
Identities = 241/846 (28%), Positives = 417/846 (48%), Gaps = 62/846 (7%)
Query: 1 MPWSPDNEGLTQLCLTLQHAVSTNSDER--------QQALDALETFKLEPQFANYLCYIL 52
M W+P +EGL QL L+ + S + + D P F NYL Y+L
Sbjct: 1 MAWTPRDEGLQQLLPILKDSQSPGKATQLAVQEVSTEDPTDLAILIGCFPDFNNYLVYVL 60
Query: 53 LHLE-EMDQLRGTAGILLKNCILGGNIV----DLGYVKSEIVRGLCLNNKFIVKITGIVI 107
+L+ E + R +G++LKN I +I L Y+K + ++ + ++ I GI+I
Sbjct: 61 TNLKTENEATRSMSGLILKNNIRMHDITLQPEHLEYIKHQCLQAVGDSSPEIRGTVGILI 120
Query: 108 AALYSTYYRQHREDPQGLITLAQLIELARDNN--EGSLKALSKMMEDGAQFFQLQWSNNQ 165
+ S + PQ L +L ++++ +D N EG+ AL K+ ED A +
Sbjct: 121 TTIASNIGLHNW--PQLLPSLCEMLD-NQDYNVCEGAFSALQKICEDSAGILE------N 171
Query: 166 VPIGELVSLFLTLMVEGKTPVVRSESINCLNNIIPLQCQELSVNLDTLLTNIFSLASSES 225
+P+ ++ FL + +P +RS +I C+N I + Q L +N+D+L+ N+ + S ++
Sbjct: 172 MPLNTMIPKFLEYF-KHSSPKIRSHAIACINQFIINRSQALMLNIDSLIQNLLDVPS-DN 229
Query: 226 SYLVKQQICQCLTLNLEFRPDKLMTHLQGIIQFMGHLIVNTDRNDSEEEKVALGACEFIL 285
V+ +C L + R D +M H+ II+ + R+ +E VAL A EF L
Sbjct: 230 DPAVRMNVCHALVGLVGVRIDLMMPHMSQIIELI------LLRSQDADENVALQATEFWL 283
Query: 286 ALVSNTNVPDHLIQPYVQELVPLLLTNMVYSQEEIVVMEASNGXXXXXXXXXXXIKPVSA 345
+L N D ++ P + +LVP+L++ Y++ +I++++ G I P
Sbjct: 284 SLGKQRNCRD-ILSPILSQLVPVLVSRTQYTETDIILLKGDVGEDDKEPDRQQDISPRFH 342
Query: 346 KIQKKXXXXXXXXXXXXXXXXXXWNLRKCAASVLDILTGIFPKEVIETALPLLREHLTSD 405
+ NLRKC+A LDI++ IF + LP+L+E L
Sbjct: 343 MSRVHGISNELDENSDDDMWDSALNLRKCSACALDIISKIFGDVCLPLMLPILKEALFHQ 402
Query: 406 SWYIREATTLSLGAMAEGGMKYFDGQLPALIPFLVEQLKSPWFPVRRMTCWTLSRFSIWI 465
W I+E+ ++LGA+AEG M+ LP LIP+L+ L VR +TCWT RF W+
Sbjct: 403 EWVIKESGVMALGAIAEGCMQGLIPHLPELIPYLITCLSDKKPLVRSITCWTFMRFPKWV 462
Query: 466 LDD-RTEFLMPVLNPIMETLLDKKKGVQEXXXXXXXXFIENSDPDIVGTVLYEPLLDRFD 524
L+ ++L P++ +++ +LD K VQE E + +V + E +L F
Sbjct: 463 LNQPHDKYLEPLIEELLKCILDSNKRVQEAACSAFVALEEEACTQLVPYL--ENMLKTFV 520
Query: 525 ECFRFYQKKNLIILYDAVSRLSEKCD---LDEQAITKLLPHLLNKWSALDDNDKELWPLL 581
F Y ++NL+I+YD V L+E Q I L+P L++KW+ + D+DK++ LL
Sbjct: 521 LAFSKYHQRNLLIMYDVVGLLAESVGHHLNKPQYIDILMPPLMDKWNLVKDDDKDIIYLL 580
Query: 582 ECLSYVSTSLGPRFAPMAMEVYNRAWNILCRCVDLEAKSQVDPTIVVPEKDFIITSLDLI 641
ECLS ++T+L F P VY + +I+ ++ + + + P+K+ ++ +LDL+
Sbjct: 581 ECLSSIATALQSSFLPYCDSVYRKGISIIEETINQDMMCKQSQSTDYPDKERMVIALDLV 640
Query: 642 DGLVQGLGYDSKALLFP-NHDTNMFSVILQCLQDHSHEVRQSAYALLGDI--AYYYERQL 698
GL++GL ++L+ P ++ + ++ QC+ D EVRQS++ALLGD+ A + +
Sbjct: 641 SGLIEGL----QSLIEPLVANSKLLQLLCQCMGDVMPEVRQSSFALLGDLSGACFSQVYP 696
Query: 699 FTSDFSKRMVETIGNELIQNGENHEAVSTVNNAIWCLGLMAHKIDLGPCIIEISRIVLD- 757
+T+ F +V+ + N V NNA+W +G + + LG R++L
Sbjct: 697 YTAHFILILVQNL---------NPSVVGVCNNAVWAIGQIC--VKLGEETKPYVRLLLSE 745
Query: 758 -LFCSTQLVLPTSIMENLCITIARLAHFHPEIFTQPPFAGETQWHKWCSIASELTDPEEK 816
+ + +P ++ N IT+ RL + P+ P+ E +WC + D +EK
Sbjct: 746 LMILMNRQDIPKNLSRNAAITLGRLGNACPD--EVAPYLPEF-LRQWCLLLRYAYDHDEK 802
Query: 817 TVSYTG 822
+S+ G
Sbjct: 803 YLSFMG 808
>At2g16950 [YU] KOG2023 Nuclear transport receptor
Karyopherin-beta2/Transportin (importin beta
superfamily)
Length = 827
Score = 277 bits (709), Expect = 5e-74
Identities = 225/820 (27%), Positives = 397/820 (47%), Gaps = 116/820 (14%)
Query: 3 WSPDNEGLTQLCLTLQHAVSTNSD-ERQQALDALETFKLEPQFANYLCYILLHLEEMD-Q 60
W P ++GL ++C L+ +S +S ++ Q L+ F P F NYL +IL+ E +
Sbjct: 8 WQPRDDGLAEICSLLEQQISPSSVVDKSQIWKQLQHFSQFPDFNNYLVFILVRAEGKSVE 67
Query: 61 LRGTAGILLKNCILGG----NIVDLGYVKSEIVRGLCLNNKFIVKITGIVIAALYSTYYR 116
+R AG+LLKN + G + Y+KSE++ L ++ I G +I+ + +
Sbjct: 68 VRQAAGLLLKNNLRGAYPSMTQENQKYIKSELLPCLGAADRNIRTTVGTIISVIVNI--- 124
Query: 117 QHREDPQGLITLAQLIELARDNNE-----GSLKALSKMMEDGAQFFQLQWSNNQVP--IG 169
E G L + D+N+ G++ ALSK+ ED + +VP
Sbjct: 125 ---EGVSGWHELLPALVTCLDSNDLNHMDGAMDALSKICEDIPHVL-----DTEVPGLAE 176
Query: 170 ELVSLFLTLMVE---GKTPVVRSESINCLNNIIPLQCQELSVNLDTLLTNIFSLASSESS 226
+++FL +++ +R ++ +N I + L +LD L +F LA+
Sbjct: 177 RPINIFLPRLLQFFQSPHASLRKLALGSVNQYIIIMPAALYNSLDKYLQGLFVLANDPVP 236
Query: 227 YLVKQQICQCLTLNLEFRPDKLMTHLQGIIQFMGHLIVNTDRNDSEEEKVALGACEFILA 286
V++ +C E P + HL+ ++++M L VN D +E+V+L ACEF A
Sbjct: 237 E-VRKLVCAAFVHLTEVLPSSIEPHLRNVMEYM--LQVNRD----PDEEVSLEACEFWSA 289
Query: 287 LVSNTNVPDHLIQPYVQELVPLLLTNMVYSQEEIVVMEASNGXXXXXXXXXXXIKPVSAK 346
+ +P ++ ++ L+P+LL NM Y+ ++ +++A +KP +
Sbjct: 290 YC-DAQLPPENLKEFLPRLIPVLLENMAYADDDESLLDAEEDESQPDRDQD--LKP---R 343
Query: 347 IQKKXXXXXXXXXXXXXXXXXXWNLRKCAASVLDILTGIFPKEVIETALPLLREHLTS-- 404
WNLRKC+A+ +D+L+ +F E++ +PL++++L++
Sbjct: 344 FHTSRLHGSEDFDDDDDDSFNVWNLRKCSAAAIDVLSNVFGDEILPALMPLIQKNLSASG 403
Query: 405 -DSWYIREATTLSLGAMAEG---GMKYFDGQLPALIPFLVEQLKSPWFPVRRMTCWTLSR 460
++W REA L+LGA+AEG G+ + ++ FL+ L + +R ++CWTLSR
Sbjct: 404 DEAWKQREAAVLALGAIAEGCMNGLYPHLSEASLIVAFLLPLLDDKFPLIRSISCWTLSR 463
Query: 461 FSIWILDDRT-----EFLMPVLNPIMETLLDKKKGVQEXXXXXXXXFIENSDPDIVGT-- 513
F +++ + E VL ++ LLD K VQE E++ ++V
Sbjct: 464 FGKYLIQESGNPKGYEQFEKVLMGLLRRLLDTNKRVQEAACSAFATVEEDAAEELVPHLG 523
Query: 514 VLYEPLLDRFDECFRFYQKKNLIILYDAVSRLSEKC--DLDEQAITKLL-PHLLNKWSAL 570
V+ + L+ F + YQ++NL I+YDA+ L++ +L++ A ++L P L+ KW L
Sbjct: 524 VILQHLMCAFGK----YQRRNLRIVYDAIGTLADSVREELNKPAYLEILMPPLVAKWQQL 579
Query: 571 DDNDKELWPLLECLSYVSTSLGPRFAPMAMEVYNRAWNILCRCVDLEAKSQVDPTIVVP- 629
++DK+L+PLLEC + +S +LG FAP A V+ R +I + L+ ++V+P
Sbjct: 580 SNSDKDLFPLLECFTSISQALGVGFAPFAQPVFQRCMDI----IQLQQLAKVNPASAGAQ 635
Query: 630 -EKDFIITSLDLIDGLVQGLGYDSKALLFPNHDTNMFSVILQCLQDHSHEVRQSAYALLG 688
+++FI+ SLDL+ GL +GLG ++L+ +N+ ++L C D + +VRQSA+AL+G
Sbjct: 636 YDREFIVCSLDLLSGLAEGLGSGIESLV---QQSNLRDLLLNCCIDEAADVRQSAFALMG 692
Query: 689 DIAYYYERQLFTSDFSKRMVETIGNELIQNGENHEAVSTVNNAIWCLGLMAHKIDLGPCI 748
D+A N E +S NNA W +G +A K
Sbjct: 693 DLAR------------------------SANLNRENLSVANNACWAIGELAVK------- 721
Query: 749 IEISRIVLDLFCSTQLVLPTSIMENLCITIARLAHFHPEI 788
+ +++EN IT+ RLA P++
Sbjct: 722 ----------------GVNKALVENSAITLGRLAWIRPDL 745
>At2g16960 [YU] KOG2023 Nuclear transport receptor
Karyopherin-beta2/Transportin (importin beta
superfamily)
Length = 547
Score = 161 bits (408), Expect = 4e-39
Identities = 132/488 (27%), Positives = 241/488 (49%), Gaps = 51/488 (10%)
Query: 369 WNLRKCAASVLDILTGIFPKEVIETALPLLREHLTS---DSWYIREATTLSLGAMAEGGM 425
WNLR C+A + IL +F E++ T +PL+ L+ ++W REA + GA+AEG
Sbjct: 16 WNLRACSAKFIGILANVFGDEILLTLMPLIEAKLSKFDDETWKEREAAVFAFGAIAEGCN 75
Query: 426 KYFDGQLPALIPFLVEQLKSPWFP-VRRMTCWTLSRFSIWILDD----RTEFLMPVLNPI 480
+F P LI ++ +L P VRR+TCWTL +F ++ ++ ++ VL+
Sbjct: 76 SFF---YPHLIVAILRRLLDDQSPLVRRITCWTLYQFGTYVFEESNLENSKLFTKVLHGF 132
Query: 481 METLLDKKKGVQEXXXXXXXXFIENSDPDIVGTVLYEPLLDRFDECFRFYQKKNLIILYD 540
LLD VQE F E++ +V + E +L + F YQK+NL +L D
Sbjct: 133 RFKLLDSNIWVQEAACLALTTFEEDAGDKLVPHL--EKILQQLMRAFGKYQKRNLKVLLD 190
Query: 541 AVSRLSEKC--DLDEQAITKLL-PHLLNKWSALDDNDKELWPLLECLSYVSTSLGPRFAP 597
A+ L++ +L+++A K+L P L++ + ++DK++ PLL+C + +S +L FAP
Sbjct: 191 AIRALADSVGINLNKRAYIKILIPPLVSTLEQISNSDKDVIPLLKCFTSISKALEVGFAP 250
Query: 598 MAMEVYNRAWNILCRCVDLEAKSQVDPTI--VVPEKDFIITSLDLIDGLVQGLGYDSKAL 655
+ V+ R +IL L+ ++VD V +++ ++ SL+ GL +GL ++L
Sbjct: 251 FSWYVFERCMDIL----QLQQLAKVDHDFAGVQYDQNIVVCSLEFFSGLSKGLVSGIESL 306
Query: 656 LFPNHDTNMFSVILQCLQDHSHEVRQSAYALLGDIA----YYYERQLFTSDFSKRMVE-- 709
+ +N+ ++L+C D + +VR+SA+AL+ + + E ++ K + E
Sbjct: 307 V---SQSNLRDMLLKCFMDETPDVRESAFALICHLTKSANFSGENLSAANNACKAIGELA 363
Query: 710 ---TIGNELIQNGEN-----HEAVSTVNNAIWCLGLMAHKIDLGPCIIEISRIVLDLFCS 761
+ N+L+ + + E V N ++ LG++ I LG + S L + +
Sbjct: 364 VKFLVKNKLVNDMNSMFQYPQEVSPIVTNVVYSLGMI---IQLGETLELKSLTTLVEYNA 420
Query: 762 TQLVLPTSIMENLCITIARLAHFHPEIFTQPPFAGETQWHKWCSIASELTDPEEKTVSYT 821
+L + N IT+ LA P++ + + E WC + L D K ++
Sbjct: 421 IELAM------NSAITVGILARIRPDLSAR---SIENFMKPWCMRLATLDDDSTKENAFQ 471
Query: 822 GFIKIMNL 829
G +++ +
Sbjct: 472 GLCEMVKV 479
>CE18112 [YU] KOG2023 Nuclear transport receptor
Karyopherin-beta2/Transportin (importin beta
superfamily)
Length = 419
Score = 144 bits (364), Expect = 5e-34
Identities = 109/380 (28%), Positives = 182/380 (47%), Gaps = 45/380 (11%)
Query: 477 LNPIMETLLDKKKGVQEXXXXXXXXFIENSDPDIVGTVLYEPLLDRFDECFRFYQKKNLI 536
L ++ LD K VQE E + ++ + +LD+ + F+ YQ KNL+
Sbjct: 10 LEQLLRCSLDGNKKVQEAACSAFATLEEEAGEQLIPFL--GEILDQLVKAFQCYQAKNLL 67
Query: 537 ILYDAVSRLSEKCD---LDEQAITKLLPHLLNKWSALDDNDKELWPLLECLSYVSTSLGP 593
ILYDA+ L+ + L+P L+ KW L D DKEL+PLLEC+S + +++G
Sbjct: 68 ILYDAIGTLANSVGDALSHPVYVQMLMPPLMEKWERLSDEDKELFPLLECISAIVSAMGQ 127
Query: 594 RFAPMAMEVYNRAWNILCRCVDLEAKSQVDP-TIVVPEKDFIITSLDLIDGLVQGLGYDS 652
F P V+ R +++ +CV + + P + PE DFII +LDL+ GL + L
Sbjct: 128 SFLPYIQPVFTRCCSLIEKCVQQNQQHIMAPDQVEAPETDFIIVALDLLSGLAESLPEHM 187
Query: 653 KALLFPNHDTNMFSVILQCLQDHSHEVRQSAYALLGDIAYYYERQLFTSDFSKRMVETIG 712
L+ ++ + ++L C D + +VRQS +ALLGD+ T +R++
Sbjct: 188 DPLV---ANSKLVELMLFCSLDVTPDVRQSCFALLGDL---------TKACPERVLPQSS 235
Query: 713 NELIQNGENHE--AVSTVNNAIWCLGLMAHKIDLGPCIIEISRIVLD---LFCSTQLVLP 767
N + +N + +S NNAIW LG +A K +GP + + +++ + ++Q +
Sbjct: 236 NFIFFLAQNLDPSKISVCNNAIWALGELALK--MGPAMKQFIGPIIEPLIVVINSQQNMQ 293
Query: 768 TSIMENLCITIARLAHF-------HPEIFTQPPFAGETQWHKWCSIASELTDPEEKTVSY 820
+++EN ITI RL H F +P C + D EK
Sbjct: 294 RTLLENTAITIGRLGQCCGEELAPHISRFVRP----------CCYSLRNIKDNAEKE--- 340
Query: 821 TGFIKIMNLMDFNAQGMPSD 840
+ FI + N+++ N G+ +D
Sbjct: 341 SAFIGLCNMINMNPVGVLND 360
>Hs19923142 [YU] KOG1241 Karyopherin (importin) beta 1
Length = 876
Score = 52.4 bits (124), Expect = 3e-06
Identities = 34/122 (27%), Positives = 56/122 (45%), Gaps = 9/122 (7%)
Query: 369 WNLRKCAASVLDILTGIFPKEVIETALPLLREHLTSDSWYIREATTLSLGAMAEGGMKYF 428
WN K A L +L +++ LP ++EH+ + W R+A ++ G + EG
Sbjct: 342 WNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPE--- 398
Query: 429 DGQLPALI----PFLVEQLKSPWFPVRRMTCWTLSRFSIWILDDRTE--FLMPVLNPIME 482
QL L+ P L+E +K P VR WT+ R + + +L P+L ++E
Sbjct: 399 PSQLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIE 458
Query: 483 TL 484
L
Sbjct: 459 GL 460
>At4g27640 [YU] KOG2171 Karyopherin (importin) beta 3
Length = 651
Score = 50.8 bits (120), Expect = 9e-06
Identities = 37/149 (24%), Positives = 63/149 (41%), Gaps = 6/149 (4%)
Query: 373 KCAASVLDILTGIFPKEVIETALPLLREHLTSDSWYIREATTLSLGAMAEGGMKYFDGQL 432
+ +A V+D L PK V L H S + REA+ +LG ++EG +L
Sbjct: 317 RASAEVIDTLAMNLPKHVFLPVLEFASVHCQSTNLKFREASVTALGVISEGCFDLMKEKL 376
Query: 433 PALIPFLVEQLKSPWFPVRRMTCWTLSRFSIWILDDRTEFLMPVLNPIMETLLDKKKGVQ 492
++ ++ L+ P VR + + +F+ + + VL ++ + D + V+
Sbjct: 377 DTVLNIVLGALRDPELVVRGAASFAIGQFAEHLQPEILSHYQSVLPCLLIAIEDTSEEVK 436
Query: 493 EXXXXXXXXFIENSDPDIVGTVLYEPLLD 521
E F EN +IV PLLD
Sbjct: 437 EKSHYALAAFCENMGEEIV------PLLD 459
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.322 0.138 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,577,114
Number of Sequences: 60738
Number of extensions: 2095139
Number of successful extensions: 4674
Number of sequences better than 1.0e-05: 12
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 4552
Number of HSP's gapped (non-prelim): 19
length of query: 884
length of database: 30,389,216
effective HSP length: 115
effective length of query: 769
effective length of database: 23,404,346
effective search space: 17997942074
effective search space used: 17997942074
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)