ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1121 good U KOG1693 Intracellular trafficking, secretion, and vesicular transport emp24/gp25L/p24 family of membrane trafficking proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1121 397698 396982 -239
(239 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL018c [U] KOG1693 emp24/gp25L/p24 family of membrane trafficki... 157 2e-38
SPAC17A5.08 [U] KOG1693 emp24/gp25L/p24 family of membrane traff... 64 2e-10
YAL007c [U] KOG1693 emp24/gp25L/p24 family of membrane trafficki... 56 5e-08
>YDL018c [U] KOG1693 emp24/gp25L/p24 family of membrane trafficking proteins
Length = 225
Score = 157 bits (396), Expect = 2e-38
Identities = 92/218 (42%), Positives = 128/218 (58%), Gaps = 10/218 (4%)
Query: 24 MYNLLNMKFTWLWVFSLVIVCQSSPITVQLQKNGKECVYIDVDDSDCKISYYFAVQEGEN 83
M NL + F + F ++SP+T +L K KEC+Y + DC ISYYFAVQ+GE+
Sbjct: 1 MSNLCVLFFQFF--FLAQFFAEASPLTFELNKGRKECLYTLTPEIDCTISYYFAVQQGES 58
Query: 84 NAFRVSYELWSPDDTEYPMIYKDDEEQGQWTFPAKHTGEYALCVIGDE-YPKIVDLDIVQ 142
N F V+YE+++PDD P+I + E QG+W+F +H GEYA+C G + + KIVDLD
Sbjct: 59 NDFDVNYEIFAPDDKNKPIIERSGERQGEWSFIGQHKGEYAICFYGGKAHDKIVDLDFKY 118
Query: 143 ICFDQIP---KPADPRLIGETIDSSLVRTLQDSV----NIIEDQLQVLERNLKLYKSRAE 195
C Q + R + S LQDSV + IE QL VLERN++ YKSR
Sbjct: 119 NCERQDDIRNERRKARKAQRNLRDSKTDPLQDSVENSIDTIERQLHVLERNIQYYKSRNT 178
Query: 196 RNHHTVKSIASRLVTISICSIVLVPTIAVLEIIIMKYI 233
RNHHTV S R+V SI I+L+ ++ +I I+++I
Sbjct: 179 RNHHTVCSTEHRIVMFSIYGILLIIGMSCAQIAILEFI 216
>SPAC17A5.08 [U] KOG1693 emp24/gp25L/p24 family of membrane trafficking proteins
Length = 210
Score = 63.5 bits (153), Expect = 2e-10
Identities = 48/195 (24%), Positives = 87/195 (44%), Gaps = 6/195 (3%)
Query: 37 VFSLVIVCQSSPITVQLQKNGKECVYIDVDDSDCKISYYFAVQEGENNAFRVSYELWSPD 96
+F L + + +T +L+ K+C Y+D + K + +AVQ G +F V Y + +P
Sbjct: 11 LFLLASLASAIELTFKLENQEKQCYYLDSFHTGEKTHFTYAVQSG--GSFDVDYMIKAPS 68
Query: 97 DTEYPMIYKDDEEQGQWTFPAKHTGEYALCVIGDEYPKIVDLDIVQICFDQIPKPADPRL 156
+ K Q F + GEY C D + IV + + + P L
Sbjct: 69 QKTVALGKK--RRQADVFFTLEEKGEYEFCF--DNHMSTFTDKIVTMEITMENELSLPAL 124
Query: 157 IGETIDSSLVRTLQDSVNIIEDQLQVLERNLKLYKSRAERNHHTVKSIASRLVTISICSI 216
+ ++Q +V I L ++R +K+R RN+ TVKS +R+ S+
Sbjct: 125 TRDEAKDYKKDSMQSTVLEISTALSEIDRVQNYFKTREHRNYSTVKSTQARIFWFSLAES 184
Query: 217 VLVPTIAVLEIIIMK 231
++V ++ L++ I+K
Sbjct: 185 IMVVALSALQVFIVK 199
>YAL007c [U] KOG1693 emp24/gp25L/p24 family of membrane trafficking proteins
Length = 215
Score = 55.8 bits (133), Expect = 5e-08
Identities = 40/187 (21%), Positives = 87/187 (46%), Gaps = 10/187 (5%)
Query: 47 SPITVQLQKNGKECVYIDVDDSDCKISYYFAVQEGENNAFRVSYELWSPDDTEYPMIYKD 106
+P+ + L KEC+Y D+ D ++ + V G N F + +++ +PD + + +
Sbjct: 30 APVAISLPAFSKECLYYDMVTEDDSLAVGYQVLTGGN--FEIDFDITAPDGS--VITSEK 85
Query: 107 DEEQGQWTFPAKHTGEYALCVIGDEYPKIVDLDIVQICFDQIPKPADPRLIGETIDSSLV 166
++ + + G+Y C + Y L V+I ++ D D +
Sbjct: 86 QKKYSDFLLKSFGVGKYTFC-FSNNYG--TALKKVEITLEKEKTLTDEHEADVNNDDIIA 142
Query: 167 RTLQDSVNIIEDQLQVLERNLKLYKSRAERNHHTVKSIASRLVTISICSIVLVPTIAVLE 226
++V I+ L + + L ++R RN TV S SRL +SI I+++ I++ +
Sbjct: 143 ---NNAVEEIDRNLNKITKTLNYLRAREWRNMSTVNSTESRLTWLSILIIIIIAVISIAQ 199
Query: 227 IIIMKYI 233
+++++++
Sbjct: 200 VLLIQFL 206
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.137 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,946,399
Number of Sequences: 60738
Number of extensions: 655750
Number of successful extensions: 1653
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1650
Number of HSP's gapped (non-prelim): 3
length of query: 239
length of database: 30,389,216
effective HSP length: 103
effective length of query: 136
effective length of database: 24,133,202
effective search space: 3282115472
effective search space used: 3282115472
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)