ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1128 check: MH L KOG1167 Replication, recombination and repair Serine/threonine protein kinase of the CDC7 subfamily involved in DNA synthesis, repair and recombination
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1128 397899 399323 475
(475 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL017w [L] KOG1167 Serine/threonine protein kinase of the CDC7 ... 427 e-119
SPBC776.12c [L] KOG1167 Serine/threonine protein kinase of the C... 232 1e-60
SPBC21C3.18 [L] KOG1167 Serine/threonine protein kinase of the C... 178 2e-44
ECU10g0120 [L] KOG1167 Serine/threonine protein kinase of the CD... 169 8e-42
ECU08g1960 [L] KOG1167 Serine/threonine protein kinase of the CD... 169 1e-41
Hs4502715 [L] KOG1167 Serine/threonine protein kinase of the CDC... 124 4e-28
7298441 [L] KOG1167 Serine/threonine protein kinase of the CDC7 ... 98 2e-20
CE26909 [L] KOG1167 Serine/threonine protein kinase of the CDC7 ... 84 5e-16
7290734 [L] KOG1167 Serine/threonine protein kinase of the CDC7 ... 82 2e-15
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 72 2e-12
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 67 4e-11
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 65 2e-10
At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit 65 3e-10
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 64 4e-10
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 64 5e-10
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 63 8e-10
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 63 8e-10
At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit 63 1e-09
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 62 1e-09
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 61 3e-09
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 61 3e-09
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 61 4e-09
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 60 7e-09
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 60 7e-09
CE08727 [G] KOG0658 Glycogen synthase kinase-3 60 7e-09
At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit 60 7e-09
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 59 1e-08
SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit 59 2e-08
CE21401 [G] KOG0658 Glycogen synthase kinase-3 59 2e-08
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 58 3e-08
CE17321 [TDK] KOG0668 Casein kinase II alpha subunit 58 3e-08
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 58 4e-08
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 58 4e-08
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 57 5e-08
YNL307c [G] KOG0658 Glycogen synthase kinase-3 57 6e-08
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 57 6e-08
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 57 6e-08
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 57 6e-08
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 57 8e-08
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 56 1e-07
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 56 1e-07
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 56 1e-07
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 55 2e-07
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 55 2e-07
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 55 2e-07
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 55 2e-07
7290342 [G] KOG0658 Glycogen synthase kinase-3 55 2e-07
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 55 3e-07
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 55 3e-07
SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase 54 4e-07
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 54 4e-07
At4g16970 [L] KOG1167 Serine/threonine protein kinase of the CDC... 54 5e-07
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 54 7e-07
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 54 7e-07
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 53 9e-07
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 53 9e-07
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 53 9e-07
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 53 9e-07
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 53 9e-07
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 52 1e-06
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 52 1e-06
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 52 1e-06
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 52 1e-06
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 52 2e-06
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 52 2e-06
7300288 [D] KOG0596 Dual specificity; serine/threonine and tyros... 52 2e-06
YMR139w [G] KOG0658 Glycogen synthase kinase-3 52 3e-06
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 52 3e-06
YOL128c [G] KOG0658 Glycogen synthase kinase-3 51 3e-06
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 51 3e-06
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 51 3e-06
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 51 3e-06
At4g28540 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 51 4e-06
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 51 4e-06
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 50 6e-06
YNL161w [R] KOG0605 NDR and related serine/threonine kinases 50 7e-06
YDR477w [T] KOG0583 Serine/threonine protein kinase 50 7e-06
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 50 7e-06
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 50 7e-06
SPBC3H7.15 [T] KOG1164 Casein kinase (serine/threonine/tyrosine ... 50 1e-05
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 50 1e-05
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 50 1e-05
>YDL017w [L] KOG1167 Serine/threonine protein kinase of the CDC7 subfamily
involved in DNA synthesis repair and recombination
Length = 507
Score = 427 bits (1097), Expect = e-119
Identities = 227/472 (48%), Positives = 300/472 (63%), Gaps = 30/472 (6%)
Query: 1 MDDIPAEIIQEMDDLYDKVPQLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWD 60
+DDIP EI +EM LY +P + + YKL+DKIGEGTFSSVYKA+D++ + + HFW+
Sbjct: 8 IDDIPPEIKEEMIQLYHDLPGIENEYKLIDKIGEGTFSSVYKAKDITGKITKKFASHFWN 67
Query: 61 KNSKHVAIKRIYVTSSPNRIXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEE 120
S +VA+K+IYVTSSP RI VAPLCDA R +DQV+ VLP+YPHEE
Sbjct: 68 YGSNYVALKKIYVTSSPQRIYNELNLLYIMTGSSRVAPLCDAKRVRDQVIAVLPYYPHEE 127
Query: 121 FRHFYRDMPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAE 180
FR FYRD+PIKGIKKY++ELL ALK+VHS GIIHRD+KPTNFL+N LGRGVLVDFGLAE
Sbjct: 128 FRTFYRDLPIKGIKKYIWELLRALKFVHSKGIIHRDIKPTNFLFNLELGRGVLVDFGLAE 187
Query: 181 ---ENEELYLPDLNYRVYVN---DQG------EKVCNC--SSPYANNKKTSHLPLISIQN 226
+ + + +Y Y N D G E+ C C + Y+ N P+++IQN
Sbjct: 188 AQMDYKSMISSQNDYDNYANTNHDGGYSMRNHEQFCPCIMRNQYSPNSHNQTPPMVTIQN 247
Query: 227 GQLNVRGANELSAAQSENLMKAELSKGYPKHEXXXXXXXXXXXXXXFRAPEVLMKCSFQT 286
G++ N+ +L+KGYPK+E FRAPEVLMKC Q+
Sbjct: 248 GKV----------VHLNNVNGVDLTKGYPKNETRRIKRANRAGTRGFRAPEVLMKCGAQS 297
Query: 287 QKIDIWSVGVILLSFISRRFPIFQSMDDIDAFLEICCIFGIKPMQEVAKFHGLGLDMTKV 346
KIDIWSVGVILLS + RRFP+FQS+DD D+ LE+C IFG K +++ A HGLG + + +
Sbjct: 298 TKIDIWSVGVILLSLLGRRFPMFQSLDDADSLLELCTIFGWKELRKCAALHGLGFEASGL 357
Query: 347 PGFHSEGYPGGLQGFVRALLDKEVEEGTLPEYSIAFETLDYLTQ--FDKQLTPSLGPDDE 404
GY GL+ FV LL+KE GT PEYS+AFET +L Q D+ PD +
Sbjct: 358 IWDKPNGYSNGLKEFVYDLLNKECTIGTFPEYSVAFETFGFLQQELHDRMSIEPQLPDPK 417
Query: 405 EDIDD----KIRSYKQAVWDDHFWCFDLLAKCFELNSYKRPSASDLLEHLWF 452
++D +++ Y++ +W DH+WCF +L +CFE++ KR SA DLL+ +F
Sbjct: 418 TNMDAVDAYELKKYQEEIWSDHYWCFQVLEQCFEMDPQKRSSAEDLLKTPFF 469
>SPBC776.12c [L] KOG1167 Serine/threonine protein kinase of the CDC7 subfamily
involved in DNA synthesis repair and recombination
Length = 507
Score = 232 bits (591), Expect = 1e-60
Identities = 163/471 (34%), Positives = 220/471 (46%), Gaps = 105/471 (22%)
Query: 1 MDDIPAEIIQEMDDLYDKVPQLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWD 60
+ DIPA +E++++ +L Y+L++KIGEGTFSSVYKA+DL GR D WD
Sbjct: 43 IQDIPARDREEIENITRTFVELQENYRLIEKIGEGTFSSVYKAEDLHY--GRYIND--WD 98
Query: 61 KNS----------------------KHVAIKRIYVTSSPNRIXXXXXXXXXXXXXXXVAP 98
S K+VAIK+IY TSSP RI +AP
Sbjct: 99 IQSEVLKESSFGKEKIPVNEDSRKPKYVAIKKIYATSSPARIYNELEILYLLRGSSVIAP 158
Query: 99 LCDAIRYQDQVVVVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSALKYVHSFGIIHRDVK 158
L A+R +DQV+VVLP+Y H +FR +Y + + Y L A++ + GIIHRD+K
Sbjct: 159 LITALRNEDQVLVVLPYYEHTDFRQYYSTFSYRDMSIYFRCLFQAMQQTQTLGIIHRDIK 218
Query: 159 PTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYRVYVNDQGEKVCNCSSPYANNKKTSH 218
P+NFL++ GVLVDFGLAE Y Q C C+ N +
Sbjct: 219 PSNFLFDVRTKHGVLVDFGLAER-------------YDGRQQSHSCRCT-----NSNAAE 260
Query: 219 LPLISIQNGQLNVRGANELSAAQSENLMKAELSKGYPKHEXXXXXXXXXXXXXXFRAPEV 278
L A++ S AQ E S GY K++ FRAPEV
Sbjct: 261 L--------------AHDFSIAQ-------ETSLGYIKNDTRPSKRANRAGTRGFRAPEV 299
Query: 279 LMKCSFQTQKIDIWSVGVILLSFISRRFPIFQSMDDIDAFLEICCIFGIKPMQEVAKFHG 338
L KCS Q+ K+DIWS GVILLSF+++RFP+F S DD+DA +EI CIFG M++ A HG
Sbjct: 300 LFKCSSQSPKVDIWSAGVILLSFLTKRFPMFNSKDDVDALMEIACIFGKSEMRQCAALHG 359
Query: 339 LGLDMTKVPGFHSEGYPGGLQGFVRALLDKEVEEGTLPEYSIAFETLDYLTQFDKQLTPS 398
+ V L +K V L I + + + + ++L
Sbjct: 360 CTFETN-----------------VSTLTEKRVNFRKL----ILWASCGSASIYKEKLRHK 398
Query: 399 LGPDDEEDIDDKIRSYKQAVWDDHFWCFDLLAKCFELNSYKRPSASDLLEH 449
P EE + C D L KC EL+ KR SA + L+H
Sbjct: 399 --PSQEERL-----------------CLDFLEKCLELDCNKRISAEEALDH 430
>SPBC21C3.18 [L] KOG1167 Serine/threonine protein kinase of the CDC7 subfamily
involved in DNA synthesis repair and recombination
Length = 429
Score = 178 bits (451), Expect = 2e-44
Identities = 146/465 (31%), Positives = 202/465 (43%), Gaps = 93/465 (20%)
Query: 3 DIPAEIIQEMDDLYDKVPQLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFW--- 59
D+ E E+ L P + Y ++ +G G+FSSV+KA D S Y + +W
Sbjct: 17 DVDREDRPEIAKLVQAFPTIEEDYHVVKLVGAGSFSSVFKAVDRHFDS---YDNSYWISS 73
Query: 60 --------DKNSK----HVAIKRIYVTSSPNRIXXXXXXXXXXXXXXXVAPLCDAIRYQD 107
DK + VA+KRIY T P+RI V + A+R+QD
Sbjct: 74 QIEDQMPHDKTKRPKNHFVALKRIYATVLPSRIQTELEMLHELRGSDCVLNMITAVRHQD 133
Query: 108 QVVVVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPI 167
QV++VLP+ H EFR FY + I Y+ +LL L ++ + GIIHRD+KP NF +NP
Sbjct: 134 QVLIVLPFIQHAEFRDFYMKYSLPEIGAYLRDLLKGLAHIDAKGIIHRDIKPGNFAWNPY 193
Query: 168 LGRGVLVDFGLAEENEELYLPDLNYRVYVNDQGEKVCNCSSPYANNKKTSHLPLISIQNG 227
RGV++DFGLA+ +E P N V D+ K+ K + P
Sbjct: 194 TQRGVILDFGLAQW-QEADAPTENCCV---DKLRKL------KQEGKYYDYFPF------ 237
Query: 228 QLNVRGANELSAAQSENLMKAELSKGYPKHEXXXXXXXXXXXXXXFRAPEVLMKCSFQTQ 287
A+ +GY H+ FRAPEVL +C QT
Sbjct: 238 ----------------EKTIADPPEGYLLHDPRPTKRADRAGTRGFRAPEVLFRCQNQTS 281
Query: 288 KIDIWSVGVILLSFISRRFPIFQSMDDIDAFLEICCIFGIKPMQEVAKFHGLGLDMTKVP 347
ID+WSVGVILL F++ R+P F+ DDIDA +E+ IFG M A HG
Sbjct: 282 SIDVWSVGVILLCFLTHRYPFFRCEDDIDAIVELAHIFGRNGMSNCALLHG--------- 332
Query: 348 GFHSEGYPGGLQGFVRALLDKEVEEGTLPEYSIAFETLDYLTQFDKQLTPSLGPDDEEDI 407
S+ P LLD++ LD L S+ +DE I
Sbjct: 333 QIWSDNIP--------TLLDQK------------HNWLD--------LIASITKNDENLI 364
Query: 408 DDKIRSYKQAVWDDHFWCFDLLAKCFELNSYKRPSASDLLEHLWF 452
+ Y+ A+ DLL K EL+ KR A L+H +F
Sbjct: 365 LETSSDYQVAL------AIDLLDKLLELHPSKRVKAKTALQHEFF 403
>ECU10g0120 [L] KOG1167 Serine/threonine protein kinase of the CDC7 subfamily
involved in DNA synthesis repair and recombination
Length = 351
Score = 169 bits (428), Expect = 8e-42
Identities = 135/428 (31%), Positives = 187/428 (43%), Gaps = 106/428 (24%)
Query: 25 RYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXX 84
+Y ++KIGEG+FS VYKA D SGR +VA+K I TSSP R+
Sbjct: 20 KYTPIEKIGEGSFSVVYKALDAE--SGR------------YVALKAITRTSSPARVLDEM 65
Query: 85 XXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSAL 144
L R +DQVV V P++ +FR F + + IK+Y+ LL A+
Sbjct: 66 MFLKTLGGRKNCMGLLGCFRNEDQVVAVFPYFEPIDFREFISNANLADIKRYLHNLLIAI 125
Query: 145 KYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYRVYVNDQGEKVC 204
++VHS GI+HRD+KP NFLYN GRG+L+DFGLA+ Y Y Q
Sbjct: 126 EHVHSNGIMHRDLKPGNFLYNKESGRGMLIDFGLAQ-----------YEEYSEGQ----- 169
Query: 205 NCSSPYANNKKTSHLPLISIQNGQLNVRGANELSAAQSENLMKAELSKGYPKHEXXXXXX 264
+A PL+ +++ GY + +
Sbjct: 170 -----HAEGGAKPAGPLLFF------------------NSVVSKTKPPGYYERDGRPPMK 206
Query: 265 XXXXXXXXFRAPEVLMKCSFQTQKIDIWSVGVILLSFISRRFPIFQSMDDIDAFLEICCI 324
FRAPEVL +C QT ID+WSVGVI L+ ++ ++P F S DDID+ +EI I
Sbjct: 207 APRAGTRGFRAPEVLFRCQRQTGAIDMWSVGVIFLTILTTQYPFFYSSDDIDSIVEIATI 266
Query: 325 FGIKPMQEVAKFHGLGLDMTKVPGFHSEGYPGGLQGFVRALLDKEVEEGTLPEYSIAFET 384
FG M++ AKF+G R+ +D ++PE I FET
Sbjct: 267 FGHAEMRKAAKFYG---------------------RVWRSNID------SIPEERIPFET 299
Query: 385 LDYLTQFDKQLTPSLGPDDEEDIDDKIRSYKQAVWDDHFWCFDLLAKCFELNSYKRPSAS 444
+ SL P E D +DLL + +L S R +AS
Sbjct: 300 ----------IVESLNPWAEVGSDG----------------YDLLYRMLDLCSSSRITAS 333
Query: 445 DLLEHLWF 452
D L H +F
Sbjct: 334 DALSHPFF 341
>ECU08g1960 [L] KOG1167 Serine/threonine protein kinase of the CDC7 subfamily
involved in DNA synthesis repair and recombination
Length = 351
Score = 169 bits (427), Expect = 1e-41
Identities = 135/428 (31%), Positives = 187/428 (43%), Gaps = 106/428 (24%)
Query: 25 RYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXX 84
+Y ++KIGEG+FS VYKA D SGR +VA+K I TSSP R+
Sbjct: 20 KYTPIEKIGEGSFSVVYKALDAE--SGR------------YVALKAITRTSSPARVLDEM 65
Query: 85 XXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSAL 144
L R +DQVV V P++ +FR F + + IK+Y+ LL A+
Sbjct: 66 MFLKTLGGRKNCMGLLGCFRNEDQVVAVFPYFEPIDFREFISNANLADIKRYLHNLLIAI 125
Query: 145 KYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYRVYVNDQGEKVC 204
++VHS GI+HRD+KP NFLYN GRG+L+DFGLA+ Y Y Q
Sbjct: 126 EHVHSNGIMHRDLKPGNFLYNKESGRGMLIDFGLAQ-----------YEEYSEGQ----- 169
Query: 205 NCSSPYANNKKTSHLPLISIQNGQLNVRGANELSAAQSENLMKAELSKGYPKHEXXXXXX 264
+A PL+ +++ GY + +
Sbjct: 170 -----HAEGGAKPAGPLLFF------------------NSVVSKTKPPGYYERDGRPPMK 206
Query: 265 XXXXXXXXFRAPEVLMKCSFQTQKIDIWSVGVILLSFISRRFPIFQSMDDIDAFLEICCI 324
FRAPEVL +C QT ID+WSVGVI L+ ++ ++P F S DDID+ +EI I
Sbjct: 207 APRAGTRGFRAPEVLFRCQRQTGAIDMWSVGVIFLTILTTQYPFFYSSDDIDSIVEIATI 266
Query: 325 FGIKPMQEVAKFHGLGLDMTKVPGFHSEGYPGGLQGFVRALLDKEVEEGTLPEYSIAFET 384
FG M++ AKF+G R+ +D ++PE I FET
Sbjct: 267 FGHAEMRKAAKFYG---------------------RVWRSNID------SIPEERIPFET 299
Query: 385 LDYLTQFDKQLTPSLGPDDEEDIDDKIRSYKQAVWDDHFWCFDLLAKCFELNSYKRPSAS 444
+ SL P E D +DLL + +L S R +AS
Sbjct: 300 ----------IVESLNPWAEIGSDG----------------YDLLYRMLDLCSSSRITAS 333
Query: 445 DLLEHLWF 452
D L H +F
Sbjct: 334 DALSHPFF 341
>Hs4502715 [L] KOG1167 Serine/threonine protein kinase of the CDC7 subfamily
involved in DNA synthesis repair and recombination
Length = 574
Score = 124 bits (310), Expect = 4e-28
Identities = 79/248 (31%), Positives = 127/248 (50%), Gaps = 15/248 (6%)
Query: 6 AEIIQEMDDLYDKVPQLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKH 65
A + ++++ LY+ VPQLS+ +K+ DKIGEGTFSSVY L+ ++ P+ +
Sbjct: 38 AGVKKDIEKLYEAVPQLSNVFKIEDKIGEGTFSSVY----LATAQLQVGPE-------EK 86
Query: 66 VAIKRIYVTSSPNRIXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFY 125
+A+K + TS P RI V + R D VV+ +P+ HE F
Sbjct: 87 IALKHLIPTSHPIRIAAELQCLTVAGGQDNVMGVKYCFRKNDHVVIAMPYLEHESFLDIL 146
Query: 126 RDMPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEEL 185
+ + +++YM L ALK +H FGI+HRDVKP+NFLYN L + LVDFGLA+ +
Sbjct: 147 NSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTHDT 206
Query: 186 YLPDLNYRVYVNDQGEKVCNCSSPYANNKKTSHLPLISIQNGQLNVRGANELSAAQSENL 245
+ L + V Q E+ CS ++ + +PL +L+ + + S +
Sbjct: 207 KIELLKF-VQSEAQQER---CSQNKSHIITGNKIPLSGPVPKELDQQSTTKASVKRPYTN 262
Query: 246 MKAELSKG 253
+ ++ +G
Sbjct: 263 AQIQIKQG 270
Score = 68.9 bits (167), Expect = 2e-11
Identities = 59/193 (30%), Positives = 89/193 (45%), Gaps = 13/193 (6%)
Query: 273 FRAPEVLMKCSFQTQKIDIWSVGVILLSFISRRFPIFQSMDDIDAFLEICCIFGIKPMQE 332
FRAPEVL KC QT ID+WS GVI LS +S R+P +++ DD+ A +I I G + +
Sbjct: 379 FRAPEVLTKCPNQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQ 438
Query: 333 VAKFHGLGLDMTK-VPGFHSEGYPGGLQGFVRAL--LDKEVEEGTLPEYSIAFETLDYLT 389
AK G + +K VP L+G + L +++ + +I+ E D+
Sbjct: 439 AAKTFGKSILCSKEVPAQDLRKLCERLRGMDSSTPKLTSDIQGHASHQPAIS-EKTDHKA 497
Query: 390 QFDKQLTP------SLGPDDEEDIDDKIRSYKQAV--WDD-HFWCFDLLAKCFELNSYKR 440
Q P S D + Y + W++ +DLL K +LN R
Sbjct: 498 SCLVQTPPGQYSGNSFKKGDSNSCEHCFDEYNTNLEGWNEVPDEAYDLLDKLLDLNPASR 557
Query: 441 PSASDLLEHLWFK 453
+A + L H +FK
Sbjct: 558 ITAEEALLHPFFK 570
>7298441 [L] KOG1167 Serine/threonine protein kinase of the CDC7 subfamily
involved in DNA synthesis repair and recombination
Length = 665
Score = 98.2 bits (243), Expect = 2e-20
Identities = 56/171 (32%), Positives = 87/171 (50%), Gaps = 7/171 (4%)
Query: 10 QEMDDLYDKVPQLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIK 69
+ + +L + +P+++ + + +IG GTFS+V L G + + + AIK
Sbjct: 129 EALKELQESIPEINKIFDVHCRIGSGTFSTVLLGT-LQRERGLV------ETQRRRFAIK 181
Query: 70 RIYVTSSPNRIXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRDMP 129
T+ P RI V + IRY D V ++P+ H+ F YR +
Sbjct: 182 HHNPTNHPERILRELECMYRIGGVENVIGINCCIRYNDNVAFIMPYMTHDRFHDIYRSLN 241
Query: 130 IKGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAE 180
I+ Y+ LL AL++VH F +IHRDVKP+N LYN G+ +L DFGLA+
Sbjct: 242 FPEIRDYLRNLLIALRHVHKFNVIHRDVKPSNILYNRRTGKFLLCDFGLAQ 292
Score = 53.1 bits (126), Expect = 9e-07
Identities = 24/62 (38%), Positives = 39/62 (62%)
Query: 273 FRAPEVLMKCSFQTQKIDIWSVGVILLSFISRRFPIFQSMDDIDAFLEICCIFGIKPMQE 332
+R PEVL++ Q+ +D+W+ GVI+LS +S P F++ D A EI +FG P+++
Sbjct: 427 YRPPEVLLRYPKQSTAVDVWAAGVIMLSLLSGLHPFFKAPHDCGALAEIINLFGDMPVRK 486
Query: 333 VA 334
A
Sbjct: 487 TA 488
>CE26909 [L] KOG1167 Serine/threonine protein kinase of the CDC7 subfamily
involved in DNA synthesis repair and recombination
Length = 411
Score = 84.0 bits (206), Expect = 5e-16
Identities = 79/326 (24%), Positives = 127/326 (38%), Gaps = 61/326 (18%)
Query: 25 RYKLLDKI-GEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXX 83
+Y+L + I GEG+F +V A + R AIK I + +
Sbjct: 26 KYQLQENIIGEGSFGTVISATCRTTQEKR--------------AIKAIRRIEKMSMLSIE 71
Query: 84 XXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPH----EEFRHFYRDMPIKGIKKYMFE 139
+ L + + V +VL +PH E H RD+ Y
Sbjct: 72 LELLSELGGHFNIVKLFEFFHFNGSVAIVLEHFPHCTATELLFHSKRDLSFA--LSYFRN 129
Query: 140 LLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYRVYVNDQ 199
LL A+ Y+H G +HRD+K +NFLY+P R LVDFGLA + ++ V ++
Sbjct: 130 LLYAVAYLHHNGYVHRDIKLSNFLYSPQTQRFRLVDFGLATVDRSKNECSRSHAVAAMER 189
Query: 200 GEKVCNCSSPYANNKKTSHLPLISIQNGQLNVRGANELSAAQSENLMKAELSKGYPKHEX 259
+ C+C K TS +G PK E
Sbjct: 190 DPECCSC-------KGTS----------------------------SPCMFCRGKPKRE- 213
Query: 260 XXXXXXXXXXXXXFRAPEVLMKCSFQTQKIDIWSVGVILLSFISRRFPIFQSMDDIDAFL 319
RAPE+L IDI+S G++LLS +S + P F D+ + +
Sbjct: 214 ----NYNVVGTPGVRAPELLFGIGLCHPSIDIFSCGIVLLSLVSVKHPFFMPKDETENIM 269
Query: 320 EICCIFGIKPMQEVAKFHGLGLDMTK 345
+ + G + ++++A GL + +++
Sbjct: 270 HLAFLLGSETIEKMAHSEGLRVTLSE 295
>7290734 [L] KOG1167 Serine/threonine protein kinase of the CDC7 subfamily
involved in DNA synthesis repair and recombination
Length = 504
Score = 81.6 bits (200), Expect = 2e-15
Identities = 38/78 (48%), Positives = 52/78 (65%)
Query: 103 IRYQDQVVVVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTNF 162
+RY V+P+ H+ F+ FY M + I++YM LL AL++VH F +IHRDVKP+NF
Sbjct: 1 MRYDASAAFVMPFMAHDRFQDFYTRMDVPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNF 60
Query: 163 LYNPILGRGVLVDFGLAE 180
LYN +LVDFGLA+
Sbjct: 61 LYNRRRREFLLVDFGLAQ 78
Score = 60.8 bits (146), Expect = 4e-09
Identities = 49/187 (26%), Positives = 86/187 (45%), Gaps = 23/187 (12%)
Query: 273 FRAPEVLMKCSFQTQKIDIWSVGVILLSFISRRFPIFQSMDDIDAFLEICCIFGIKPMQE 332
+R PEVL+K QT +D+W+ GVI LS +S +P F++ +D A EI IFG + +++
Sbjct: 278 YRPPEVLLKYPDQTTAVDVWAAGVIFLSIMSTVYPFFKAPNDFIALAEIVTIFGDQAIRK 337
Query: 333 VAKFHGLGLDMTKVPGFHSEGYPGGLQGFVRALLDKEV--EEGTLPEYSIAFETLDYLTQ 390
A L + ++ P L+ + V + L Y + +
Sbjct: 338 TA------LALDRMITLSQRSRPLNLRKLCLRFRYRSVFSDAKLLKSYESVDGSCEVCRN 391
Query: 391 FDKQLTPSLGPDDEEDIDDKIRSYKQAVWDDHFWCF-----DLLAKCFELNSYKRPSASD 445
D+ L +D + + + + +Y+ CF DLL + E+N +KR +A +
Sbjct: 392 CDQYFFNCL-CEDSDYLTEPLDAYE---------CFPPSAYDLLDRLLEINPHKRITAEE 441
Query: 446 LLEHLWF 452
L+H +F
Sbjct: 442 ALKHPFF 448
>YOR061w [TDK] KOG0668 Casein kinase II alpha subunit
Length = 339
Score = 71.6 bits (174), Expect = 2e-12
Identities = 57/189 (30%), Positives = 87/189 (45%), Gaps = 37/189 (19%)
Query: 24 SRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIY--------VTS 75
S Y++++KIG G +S V+ + + N + K K V +K+IY +T
Sbjct: 48 SNYEIINKIGRGKYSEVFSGRCIVNNQKCVI------KVLKPVKMKKIYRELKILTNLTG 101
Query: 76 SPNRIXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPW--YPHEEFRHFYRDMPIKGI 133
PN V L D ++ D + L + + +FR Y + I
Sbjct: 102 GPN-----------------VVGLYDIVQDADSKIPALIFEEIKNVDFRTLYPTFKLPDI 144
Query: 134 KKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYR 193
+ Y +LL AL Y HS GI+HRDVKP N + +P + L+D+GLA E Y P ++Y
Sbjct: 145 QYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLA----EFYHPGVDYN 200
Query: 194 VYVNDQGEK 202
V V + K
Sbjct: 201 VRVASRYHK 209
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 67.4 bits (163), Expect = 4e-11
Identities = 47/159 (29%), Positives = 78/159 (48%), Gaps = 20/159 (12%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVT--SSPNRIXXX 83
Y+ L K+GEG++ +V K + + +G++ VAIK Y S N+I
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKN--TGQI------------VAIKIFYERPEQSVNKIAMR 49
Query: 84 XXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPH---EEFRHFYRDMPIKGIKKYMFEL 140
+ L + R + ++ +V + H +E +H+ + K ++KY+F++
Sbjct: 50 EIKFLKQFHHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQI 109
Query: 141 LSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
L A+ Y+HS IIHRD+KP N L + G L DFG A
Sbjct: 110 LRAIDYLHSNNIIHRDIKPENILVSQ-SGITKLCDFGFA 147
>Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 350
Score = 65.5 bits (158), Expect = 2e-10
Identities = 49/173 (28%), Positives = 80/173 (45%), Gaps = 21/173 (12%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
Y+L+ K+G G +S V++A +++N ++ V +K I +I
Sbjct: 40 YQLVRKLGRGKYSEVFEAINITN--------------NERVVVK-ILKPVKKKKIKREVK 84
Query: 86 XXXXXXXXXXVAPLCDAIR--YQDQVVVVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSA 143
+ L D ++ +V + + +F+ Y+ + I+ YM+ELL A
Sbjct: 85 ILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKA 144
Query: 144 LKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYRVYV 196
L Y HS GI+HRDVKP N + + + L+D+GLA E Y P Y V V
Sbjct: 145 LDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA----EFYHPAQEYNVRV 193
>At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 64.7 bits (156), Expect = 3e-10
Identities = 48/173 (27%), Positives = 77/173 (43%), Gaps = 21/173 (12%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
Y+++ K+G G +S V++ ++ NSK I +I +I
Sbjct: 34 YEVVRKVGRGKYSEVFEGINV---------------NSKEKCIIKILKPVKKKKIRREIK 78
Query: 86 XXXXXXXXXXVAPLCDAIRYQDQVV--VVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSA 143
+ L D +R Q ++ + +F+ Y + I+ Y++ELL A
Sbjct: 79 ILQNLCGGPNIVKLLDVVRDQHSKTPSLIFEYVNSTDFKVLYPTLTDYDIRYYIYELLKA 138
Query: 144 LKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYRVYV 196
L + HS GI+HRDVKP N + + L + L+D+GLA E Y P Y V V
Sbjct: 139 LDFCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLA----EFYHPGKEYNVRV 187
>Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 391
Score = 64.3 bits (155), Expect = 4e-10
Identities = 51/175 (29%), Positives = 80/175 (45%), Gaps = 25/175 (14%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
Y+L+ K+G G +S V++A +++N N K V +I +I
Sbjct: 39 YQLVRKLGRGKYSEVFEAINITN-------------NEKVVV--KILKPVKKKKIKREIK 83
Query: 86 XXXXXXXXXXVAPLCDAIRYQDQV----VVVLPWYPHEEFRHFYRDMPIKGIKKYMFELL 141
+ L D ++ D V +V + +F+ Y+ + I+ YM+E+L
Sbjct: 84 ILENLRGGPNIITLADIVK--DPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEIL 141
Query: 142 SALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYRVYV 196
AL Y HS GI+HRDVKP N + + + L+D+GLA E Y P Y V V
Sbjct: 142 KALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA----EFYHPGQEYNVRV 192
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 63.9 bits (154), Expect = 5e-10
Identities = 49/183 (26%), Positives = 82/183 (44%), Gaps = 26/183 (14%)
Query: 24 SRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXX 83
SRYK+L+KIGEG V+KA DL + +K VAIK++ + + I
Sbjct: 7 SRYKMLEKIGEGVHGCVFKAIDL--------------QRNKEVAIKKVALKNKFGNIALN 52
Query: 84 XXXXXXXXXXXXVAPLCDAIRYQDQVV---VVLPWYPHEEFRHFYRDM-PI--KGIKKYM 137
+ D I + +VL + P + ++ P+ + ++K+
Sbjct: 53 TLREIKTLQLCKSEYILDIIDIYPDLTGLSLVLEYQPDTLYNRLKSEVNPLSRQQVRKFA 112
Query: 138 FELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA-----EENEELYLPDLNY 192
++ + Y+H G++HRD+KP N L + + DFGLA E+ LY P ++
Sbjct: 113 HQMFKGIAYLHEAGLMHRDIKPANLLISD-TDMLKIADFGLARLYFPEDESRLYSPQVST 171
Query: 193 RVY 195
R Y
Sbjct: 172 RWY 174
>Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 264
Score = 63.2 bits (152), Expect = 8e-10
Identities = 46/162 (28%), Positives = 79/162 (48%), Gaps = 24/162 (14%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
++ ++KIGEGT+ VYKA++ ++G + VA+K+I + + +
Sbjct: 4 FQKVEKIGEGTYGVVYKARN--KLTGEV------------VALKKIRLDTETEGVPSTAI 49
Query: 86 XXXXXXXXXX---VAPLCDAIRYQDQVVVVLPWYPHEEFRHFY-----RDMPIKGIKKYM 137
+ L D I ++++ +V + H++ + F +P+ IK Y+
Sbjct: 50 REISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-HQDLKKFMDASALTGIPLPLIKSYL 108
Query: 138 FELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
F+LL L + HS ++HRD+KP N L N G L DFGLA
Sbjct: 109 FQLLQGLAFCHSHRVLHRDLKPQNLLIN-TEGAIKLADFGLA 149
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 63.2 bits (152), Expect = 8e-10
Identities = 46/162 (28%), Positives = 79/162 (48%), Gaps = 24/162 (14%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
++ ++KIGEGT+ VYKA++ ++G + VA+K+I + + +
Sbjct: 4 FQKVEKIGEGTYGVVYKARN--KLTGEV------------VALKKIRLDTETEGVPSTAI 49
Query: 86 XXXXXXXXXX---VAPLCDAIRYQDQVVVVLPWYPHEEFRHFY-----RDMPIKGIKKYM 137
+ L D I ++++ +V + H++ + F +P+ IK Y+
Sbjct: 50 REISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-HQDLKKFMDASALTGIPLPLIKSYL 108
Query: 138 FELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
F+LL L + HS ++HRD+KP N L N G L DFGLA
Sbjct: 109 FQLLQGLAFCHSHRVLHRDLKPQNLLIN-TEGAIKLADFGLA 149
>At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 62.8 bits (151), Expect = 1e-09
Identities = 48/173 (27%), Positives = 78/173 (44%), Gaps = 21/173 (12%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
Y+++ K+G G +S V++ +++N N K I +I +I
Sbjct: 34 YEVVRKVGRGKYSEVFEGINMNN-------------NEK--CIIKILKPVKKKKIRREIK 78
Query: 86 XXXXXXXXXXVAPLCDAIRYQDQVV--VVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSA 143
+ L D +R Q ++ + +F+ Y + I+ Y++ELL A
Sbjct: 79 ILQNLCGGPNIVKLLDVVRDQHSKTPSLIFEYVNSTDFKVLYPTLTDYDIRYYIYELLKA 138
Query: 144 LKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYRVYV 196
L + HS GI+HRDVKP N + + L + L+D+GLA E Y P Y V V
Sbjct: 139 LDFCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLA----EFYHPGKEYNVRV 187
>ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 319
Score = 62.4 bits (150), Expect = 1e-09
Identities = 32/86 (37%), Positives = 47/86 (54%), Gaps = 4/86 (4%)
Query: 111 VVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGR 170
++ + HE++ + + K I +Y ++LSAL Y HS GIIHRD+KP N + N
Sbjct: 106 LIFEYIEHEDYAKIFEKLCYKDIVEYSRQILSALSYCHSMGIIHRDIKPQNMVINQARRE 165
Query: 171 GVLVDFGLAEENEELYLPDLNYRVYV 196
++D+GLA E Y P Y V V
Sbjct: 166 LKIIDWGLA----EFYHPKKEYSVRV 187
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 61.2 bits (147), Expect = 3e-09
Identities = 51/181 (28%), Positives = 80/181 (44%), Gaps = 15/181 (8%)
Query: 5 PAEIIQEM--DDLYDKVPQLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKN 62
P II+E D +V QLS Y +G G+F V + + + S DK
Sbjct: 11 PFRIIKETARDGSTGEVKQLS--YTSSKVVGSGSFGVVMQVHLIESDSKAAIKRVLQDKR 68
Query: 63 SKHVAIKRIYVTSSPNRIXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFR 122
K+ ++ + + PN + V Y + V+ +P + R
Sbjct: 69 FKNRELQIMRIMKHPNIVDLIAYYYTTGDNSDEV--------YLNLVLEFMPETIYRASR 120
Query: 123 HFYRD---MPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
+ R MP+ +K Y+++LL +L Y+H+ GI HRD+KP N L +P G L DFG A
Sbjct: 121 LYTRQKLSMPMLEVKLYIYQLLRSLAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSA 180
Query: 180 E 180
+
Sbjct: 181 K 181
>7289745 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 336
Score = 61.2 bits (147), Expect = 3e-09
Identities = 49/171 (28%), Positives = 78/171 (44%), Gaps = 17/171 (9%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
Y+L+ K+G G +S V++A +++ + K K V K+I I
Sbjct: 37 YQLVRKLGRGKYSEVFEAINITTTEKCVV------KILKPVKKKKI-----KREIKILEN 85
Query: 86 XXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSALK 145
+A + D + ++ + +F+ Y+ + I+ Y+FELL AL
Sbjct: 86 LRGGTNIITLLAVVKDPVSRTP--ALIFEHVNNTDFKQLYQTLTDYEIRYYLFELLKALD 143
Query: 146 YVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYRVYV 196
Y HS GI+HRDVKP N + + + L+D+GLA E Y P Y V V
Sbjct: 144 YCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA----EFYHPGQEYNVRV 190
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 60.8 bits (146), Expect = 4e-09
Identities = 45/161 (27%), Positives = 77/161 (46%), Gaps = 22/161 (13%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
++ ++KIGEGT+ VYKA++ +G+L VA+K+I + +
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRE--TGQL------------VALKKIRLDLEMEGVPSTAI 49
Query: 86 XXXXXXXXXX---VAPLCDAIRYQDQVVVVLPWYPHEEFRHFYR----DMPIKGIKKYMF 138
+ L D + + ++ +V + + ++ ++P+ IK Y+F
Sbjct: 50 REISLLKELKHPNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLF 109
Query: 139 ELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
+LL + + HS +IHRD+KP N L N LG L DFGLA
Sbjct: 110 QLLQGVSFCHSHRVIHRDLKPQNLLINE-LGAIKLADFGLA 149
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 60.1 bits (144), Expect = 7e-09
Identities = 31/80 (38%), Positives = 47/80 (58%), Gaps = 3/80 (3%)
Query: 105 YQDQVVVVLPWYPHEEFRHFYR---DMPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTN 161
Y + V+ +P + RH+ R +P+ +K YM++L +L Y+HSFGI HRD+KP N
Sbjct: 127 YLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQN 186
Query: 162 FLYNPILGRGVLVDFGLAEE 181
L +P L DFG A++
Sbjct: 187 LLLDPDTAVLKLCDFGSAKQ 206
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 60.1 bits (144), Expect = 7e-09
Identities = 31/80 (38%), Positives = 47/80 (58%), Gaps = 3/80 (3%)
Query: 105 YQDQVVVVLPWYPHEEFRHFYR---DMPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTN 161
Y + V+ +P + RH+ R +P+ +K YM++L +L Y+HSFGI HRD+KP N
Sbjct: 127 YLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQN 186
Query: 162 FLYNPILGRGVLVDFGLAEE 181
L +P L DFG A++
Sbjct: 187 LLLDPDTAVLKLCDFGSAKQ 206
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 60.1 bits (144), Expect = 7e-09
Identities = 52/183 (28%), Positives = 80/183 (43%), Gaps = 32/183 (17%)
Query: 21 QLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRI 80
++ ++ L IG G+F +VYKA +N + +AIK+I V +R
Sbjct: 32 EVEIQFTNLQLIGTGSFGAVYKA--------------VLRENDEPIAIKKIKVD---DRF 74
Query: 81 XXXXXXXXXXXXXXXVAPLCDAIRYQDQ-----VVVVLPW---YPHEEFRHFYRDMPIKG 132
+ L Q + V+ +P Y H +F H + MP
Sbjct: 75 KSRELTIMHEMDHPNIIRLLYYYVMQQENCLNFVMEFMPKDLAYVHRQFAHNDKQMPAYS 134
Query: 133 IKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA---EENEELYLPD 189
IK YMF+LL + ++H I+HRD+KP N L + G + DFG A E+NE P+
Sbjct: 135 IKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEKNE----PN 190
Query: 190 LNY 192
+ Y
Sbjct: 191 ITY 193
>At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 60.1 bits (144), Expect = 7e-09
Identities = 45/173 (26%), Positives = 77/173 (44%), Gaps = 21/173 (12%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
Y+++ K+G G +S V++ +++ N+ + +I +I
Sbjct: 34 YEVVRKVGRGKYSEVFEGKNV---------------NTNERCVIKILKPVKKKKIKREIK 78
Query: 86 XXXXXXXXXXVAPLCDAIRYQDQVV--VVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSA 143
+ L D +R + +V + +F+ Y + I+ Y++ELL A
Sbjct: 79 ILQNLCGGPNIVKLYDIVRDEHSKTPSLVFEFVNSVDFKVLYPTLTDYDIRYYIYELLKA 138
Query: 144 LKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYRVYV 196
L + HS GI+HRDVKP N + + L + L+D+GLA E Y P Y V V
Sbjct: 139 LDFCHSQGIMHRDVKPHNVMIDHQLRKLRLIDWGLA----EFYHPGKEYNVRV 187
>YIL035c [TDK] KOG0668 Casein kinase II alpha subunit
Length = 372
Score = 59.3 bits (142), Expect = 1e-08
Identities = 35/86 (40%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
Query: 111 VVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGR 170
+V + + +FR Y + I+ YMFELL AL Y HS GI+HRDVKP N + + +
Sbjct: 150 LVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKK 209
Query: 171 GVLVDFGLAEENEELYLPDLNYRVYV 196
L+D+GLA E Y ++ Y V V
Sbjct: 210 LRLIDWGLA----EFYHVNMEYNVRV 231
>SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 332
Score = 58.5 bits (140), Expect = 2e-08
Identities = 46/173 (26%), Positives = 77/173 (43%), Gaps = 21/173 (12%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
Y+++ K+G G +S V++ ++ N NSK I ++ +I
Sbjct: 43 YEIIRKVGRGKYSEVFEGLNVLN-------------NSK--CIIKVLKPVKYKKIKREIK 87
Query: 86 XXXXXXXXXXVAPLCDAIRYQDQVV--VVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSA 143
+ L D +R + ++ + + +FR Y + I+ Y +ELL A
Sbjct: 88 ILQNLAGGPNIISLLDIVRDPESKTPSLIFEFVDNIDFRTLYPTLSDYDIRYYSYELLKA 147
Query: 144 LKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYRVYV 196
L + HS GI+HRDVKP N + + + L+D+GLA E Y + Y V V
Sbjct: 148 LDFCHSRGIMHRDVKPHNVMIDHKKRKLRLIDWGLA----EFYHAGMEYNVRV 196
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 58.5 bits (140), Expect = 2e-08
Identities = 30/79 (37%), Positives = 47/79 (58%), Gaps = 3/79 (3%)
Query: 105 YQDQVVVVLPWYPHEEFRHFYRD---MPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTN 161
Y + ++ +P + RH+ + +P+ +K YM++LL +L Y+HS GI HRD+KP N
Sbjct: 107 YLNLILEYVPETVYRVARHYSKQRQQIPMIYVKLYMYQLLRSLAYIHSIGICHRDIKPQN 166
Query: 162 FLYNPILGRGVLVDFGLAE 180
L +P G L DFG A+
Sbjct: 167 LLIDPESGVLKLCDFGSAK 185
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 58.2 bits (139), Expect = 3e-08
Identities = 52/175 (29%), Positives = 76/175 (42%), Gaps = 32/175 (18%)
Query: 19 VPQLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKH-VAIKRIYV---- 73
V + RY+ LD +GEG F++VYKA+D KN+ VAIK+I +
Sbjct: 5 VKSRAKRYEKLDFLGEGQFATVYKARD---------------KNTNQIVAIKKIKLGHRS 49
Query: 74 --TSSPNRIXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRDMPI- 130
NR + L DA ++ + +V + + +D +
Sbjct: 50 EAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFD-FMETDLEVIIKDNSLV 108
Query: 131 ---KGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGV--LVDFGLAE 180
IK YM L L+Y+H I+HRD+KP N L + GV L DFGLA+
Sbjct: 109 LTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDE---NGVLKLADFGLAK 160
>CE17321 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 360
Score = 58.2 bits (139), Expect = 3e-08
Identities = 45/173 (26%), Positives = 75/173 (43%), Gaps = 21/173 (12%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
Y+L+ K+G G +S V++ +S + V +K I +I
Sbjct: 38 YQLVRKLGRGKYSEVFEGFKMST--------------DEKVVVK-ILKPVKKKKIKREIK 82
Query: 86 XXXXXXXXXXVAPLCDAIR--YQDQVVVVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSA 143
+ L D ++ ++ + +F+ Y+ + I+ Y++ELL A
Sbjct: 83 ILENLRGGTNIITLLDVVKDPISRTPALIFEHVNNSDFKQLYQTLSDYDIRYYLYELLKA 142
Query: 144 LKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYRVYV 196
L + HS GI+HRDVKP N + + L+D+GLA E Y P +Y V V
Sbjct: 143 LDFCHSQGIMHRDVKPHNVMIDAEKRELRLIDWGLA----EFYHPRQDYNVRV 191
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 57.8 bits (138), Expect = 4e-08
Identities = 42/161 (26%), Positives = 75/161 (46%), Gaps = 21/161 (13%)
Query: 25 RYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXX 84
+Y+ L+KIGEGT+ +V+KA++ + + VA+KR+ + +
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNR--------------ETHEIVALKRVRLDDDDEGVPSSA 48
Query: 85 XXXX---XXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYR---DMPIKGIKKYMF 138
+ L D + ++ +V + + ++F D+ + +K ++F
Sbjct: 49 LREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLF 108
Query: 139 ELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
+LL L + HS ++HRD+KP N L N G L DFGLA
Sbjct: 109 QLLKGLGFCHSRNVLHRDLKPQNLLINR-NGELKLADFGLA 148
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 57.8 bits (138), Expect = 4e-08
Identities = 46/163 (28%), Positives = 75/163 (45%), Gaps = 22/163 (13%)
Query: 23 SSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNR--I 80
+S Y L+K+GEG++++VYK +S ++G+L VA+K I + +
Sbjct: 49 ASSYLNLEKLGEGSYATVYKG--ISRINGQL------------VALKVISMNAEEGVPFT 94
Query: 81 XXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRDMP----IKGIKKY 136
+ L D I ++ + V Y H + + P ++ +
Sbjct: 95 AIREASLLKGLKHANIVLLHDIIHTKETLTFVFE-YMHTDLAQYMSQHPGGLHPHNVRLF 153
Query: 137 MFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
MF+LL L Y+H ++HRD+KP N L + LG L DFGLA
Sbjct: 154 MFQLLRGLAYIHHQHVLHRDLKPQNLLISH-LGELKLADFGLA 195
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 57.4 bits (137), Expect = 5e-08
Identities = 40/164 (24%), Positives = 74/164 (44%), Gaps = 25/164 (15%)
Query: 25 RYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXX 84
+Y+ ++KIGEGT+ VYKA+D ++ +A+K+I + +
Sbjct: 3 QYEKVEKIGEGTYGVVYKARD--------------KVTNETIALKKIRLEQEDEGVPSTA 48
Query: 85 XXXXXXXXX---XXVAPLCDAIRYQDQVVVVLPWYPHEEFRH------FYRDMPIKGIKK 135
+ D + + ++ +V + + +H F +D+ + IK
Sbjct: 49 IREISLLKEMQHSNIVKYDDVVHSEKRLYLVFEYLDLDLKKHMDSTPDFSKDLHM--IKT 106
Query: 136 YMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
Y++++L + Y HS ++HRD+KP N L + L DFGLA
Sbjct: 107 YLYQILRGIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLA 150
>YNL307c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 57.0 bits (136), Expect = 6e-08
Identities = 49/172 (28%), Positives = 74/172 (42%), Gaps = 22/172 (12%)
Query: 31 KIGEGTFSSV---YKAQDLSNVSG----RLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXX 83
KIG G F +V Y QD N G + P H + S+ + I RI PN +
Sbjct: 40 KIGRGAFGTVVQAYLTQDKKNWLGPFAIKKVPAHT-EYKSRELQILRI--ADHPNIVKLQ 96
Query: 84 XXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYR---DMPIKGIKKYMFEL 140
V YQ + LP E + +MP+K I+ Y +++
Sbjct: 97 YFFTHLSPQDNKV--------YQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQI 148
Query: 141 LSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNY 192
+ Y+H G+ HRD+KP+N L +P G + DFG A++ E P ++Y
Sbjct: 149 ARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEH-NQPSISY 199
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 57.0 bits (136), Expect = 6e-08
Identities = 30/80 (37%), Positives = 46/80 (57%), Gaps = 3/80 (3%)
Query: 105 YQDQVVVVLPWYPHEEFRHFYR---DMPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTN 161
Y + V+ +P + RHF + +PI +K YM++L +L Y+HS G+ HRD+KP N
Sbjct: 190 YLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQN 249
Query: 162 FLYNPILGRGVLVDFGLAEE 181
L +P L DFG A++
Sbjct: 250 LLVDPDTAVLKLCDFGSAKQ 269
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 57.0 bits (136), Expect = 6e-08
Identities = 30/80 (37%), Positives = 46/80 (57%), Gaps = 3/80 (3%)
Query: 105 YQDQVVVVLPWYPHEEFRHFYR---DMPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTN 161
Y + V+ +P + RHF + +PI +K YM++L +L Y+HS G+ HRD+KP N
Sbjct: 190 YLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQN 249
Query: 162 FLYNPILGRGVLVDFGLAEE 181
L +P L DFG A++
Sbjct: 250 LLVDPDTAVLKLCDFGSAKQ 269
>At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 432
Score = 57.0 bits (136), Expect = 6e-08
Identities = 46/173 (26%), Positives = 76/173 (43%), Gaps = 21/173 (12%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
Y+++ K+G G +S V++ ++ N K V +I +I
Sbjct: 132 YEVVRKVGRGKYSEVFEGIHATD-------------NEKCVI--KILKPVKKKKIKREIK 176
Query: 86 XXXXXXXXXXVAPLCDAIRYQDQVV--VVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSA 143
+ L D +R Q ++ +++F+ Y + ++ Y+FELL A
Sbjct: 177 ILQNLCGGPNIVKLLDIVRDQQSKTPSLIFEHVNNKDFKVLYPTLSDYDVRYYIFELLKA 236
Query: 144 LKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYRVYV 196
L + HS GI+HRDVKP N + + + L+D+GLA E Y P Y V V
Sbjct: 237 LDFCHSRGIMHRDVKPHNVMIDHEQRKLRLIDWGLA----EFYHPGKEYNVRV 285
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 56.6 bits (135), Expect = 8e-08
Identities = 46/160 (28%), Positives = 73/160 (44%), Gaps = 22/160 (13%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNR--IXXX 83
Y+ L+K+GEG++++VYK + S V+G+L VA+K I +
Sbjct: 117 YEKLEKLGEGSYATVYKGK--SKVNGKL------------VALKVIRLQEEEGTPFTAIR 162
Query: 84 XXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRDMP----IKGIKKYMFE 139
+ L D I ++ + +V Y H + + P +K ++F+
Sbjct: 163 EASLLKGLKHANIVLLHDIIHTKETLTLVFE-YVHTDLCQYMDKHPGGLHPDNVKLFLFQ 221
Query: 140 LLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
LL L Y+H I+HRD+KP N L + G L DFGLA
Sbjct: 222 LLRGLSYIHQRYILHRDLKPQNLLISD-TGELKLADFGLA 260
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 56.2 bits (134), Expect = 1e-07
Identities = 40/165 (24%), Positives = 70/165 (42%), Gaps = 13/165 (7%)
Query: 20 PQLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNR 79
P+ + Y +G G+F V++A+ L D+ K+ ++ + + PN
Sbjct: 63 PKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKNRELQTMRLLDHPNV 122
Query: 80 IXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYR---DMPIKGIKKY 136
+ Y + V+ +P H +H+ + MP+ +K Y
Sbjct: 123 VSLKHCFFSTTEKDEL---------YLNLVLEYVPETVHRVIKHYNKLNQRMPLIYVKLY 173
Query: 137 MFELLSALKYVHS-FGIIHRDVKPTNFLYNPILGRGVLVDFGLAE 180
+++ AL Y+H G+ HRD+KP N L NP + L DFG A+
Sbjct: 174 TYQIFRALSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAK 218
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 55.8 bits (133), Expect = 1e-07
Identities = 43/150 (28%), Positives = 63/150 (41%), Gaps = 7/150 (4%)
Query: 32 IGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXXXXXXXX 91
+G G+F V +A+ + DK K+ ++ + S PN I
Sbjct: 31 LGSGSFGVVIQAKLVGTPGFIAVKRVLQDKRYKNRELQIMRAISHPN-IIKLIAFFHTHN 89
Query: 92 XXXXVAPLCDAIRYQDQVVVV-LPWYPHEEFRHFYRDMPIKGIKKYMFELLSALKYVHSF 150
LC + Y + V + WY + +P IK Y F+L AL Y+HS
Sbjct: 90 PSKDETHLCLLLEYMPETVFDDMRWYTRRR-----KSIPNLSIKLYAFQLFRALAYLHST 144
Query: 151 GIIHRDVKPTNFLYNPILGRGVLVDFGLAE 180
G+ HRD+KP N L + G L DFG A+
Sbjct: 145 GVCHRDIKPQNLLVDYKTGILKLCDFGSAK 174
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 55.8 bits (133), Expect = 1e-07
Identities = 42/165 (25%), Positives = 71/165 (42%), Gaps = 13/165 (7%)
Query: 20 PQLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNR 79
P+ + Y +G+G+F V++A+ L DK K+ ++ + + PN
Sbjct: 68 PKQTISYMAERIVGQGSFGIVFQAKCLETGETVAIKKVLQDKRYKNRELQTMRLLDHPNV 127
Query: 80 IXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRD---MPIKGIKKY 136
+ Y + V+ +P + +H+ R MPI +K Y
Sbjct: 128 VSLKHCFFSTTEKDEL---------YLNLVLEYVPETVYRVSKHYSRANQRMPIIYVKLY 178
Query: 137 MFELLSALKYVHS-FGIIHRDVKPTNFLYNPILGRGVLVDFGLAE 180
+++ AL Y+H G+ HRD+KP N L NP + L DFG A+
Sbjct: 179 TYQICRALAYIHGGVGVCHRDIKPQNLLVNPHTHQVKLCDFGSAK 223
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 55.5 bits (132), Expect = 2e-07
Identities = 39/165 (23%), Positives = 70/165 (41%), Gaps = 13/165 (7%)
Query: 20 PQLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNR 79
P+ + Y +G G+F V++A+ L D+ K+ ++ + + PN
Sbjct: 67 PKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKNRELQTMRLLDHPNV 126
Query: 80 IXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYR---DMPIKGIKKY 136
+ Y + V+ +P H +H+ + MP+ +K Y
Sbjct: 127 VSLKHCFFSTTEKDEL---------YLNLVLEYVPETVHRVIKHYNKLNQRMPLVYVKLY 177
Query: 137 MFELLSALKYVHS-FGIIHRDVKPTNFLYNPILGRGVLVDFGLAE 180
+++ +L Y+H G+ HRD+KP N L NP + L DFG A+
Sbjct: 178 TYQIFRSLSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAK 222
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 55.5 bits (132), Expect = 2e-07
Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 15/162 (9%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSN------VSGRLYPDHFWDKNS--KHVAIKRIYVTSSP 77
++ L+K+GEGT+ VY+A++ + RL+ D ++ + ++I R+ + P
Sbjct: 14 FEKLEKVGEGTYGKVYRAREKATGKIVALKKTRLHEDEEGVPSTTLREISILRM-LARDP 72
Query: 78 NRIXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRDMPIKGIKKYM 137
+ + V L Y D V FR +++P + IK M
Sbjct: 73 HVVRLMDVKQGLSKEGKTVLYL--VFEYMDTDVKKFI----RSFRSTGKNIPTQTIKSLM 126
Query: 138 FELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
++L + + H GI+HRD+KP N L +P R + D GLA
Sbjct: 127 YQLCKGMAFCHGHGILHRDLKPHNLLMDPKTMRLKIADLGLA 168
>CE21879 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 328
Score = 55.1 bits (131), Expect = 2e-07
Identities = 43/174 (24%), Positives = 73/174 (41%), Gaps = 44/174 (25%)
Query: 24 SRYKLLDKIGEGTFSSVYKAQDLSN-----------VSG-------RLYPDHFWDKNSKH 65
+++K + IG+G F V+ A+ L+N + G ++ +++ KN KH
Sbjct: 4 NQFKPIKSIGKGAFGQVFLAEKLNNPRIKVAMKKINIFGAPKEFLEQIQQEYYIQKNMKH 63
Query: 66 VAIKRIYVTSSPNRIXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFY 125
I ++Y S L + I +++
Sbjct: 64 KNIVKMYGMSMDTEFCYLFQEFVTG------GDLFEKIDFEN------------------ 99
Query: 126 RDMPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
MP+ +K Y+ +L+S LKY+H GI+HRD+KP N L N + DFGL+
Sbjct: 100 -GMPVNQVKGYLKQLMSGLKYIHGCGIVHRDIKPDNLLINSSDALKI-ADFGLS 151
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/166 (26%), Positives = 75/166 (44%), Gaps = 29/166 (17%)
Query: 25 RYKLLDKIGEGTFSSVYKAQDLSN-----VSGRLYPDHFWDKNSKHVAIKRIYVTSSPNR 79
RYK+L+++G+GT SVYKA +L V ++W++ +K + + P+
Sbjct: 11 RYKILEELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECVNLREVKALRKLNHPH- 69
Query: 80 IXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFY-RDMPIKG--IKKY 136
+ L + +R +++ + H + R+ P I+ +
Sbjct: 70 ----------------IIKLKEIVREHNELFFIFECMDHNLYHIMKERERPFSEGEIRSF 113
Query: 137 MFELLSALKYVHSFGIIHRDVKPTNFLY-NPILGRGVLVDFGLAEE 181
M ++L L ++H G HRD+KP N L N IL + DFGLA E
Sbjct: 114 MSQMLQGLAHMHKNGYFHRDLKPENLLVTNNIL---KIADFGLARE 156
Score = 50.1 bits (118), Expect = 7e-06
Identities = 22/54 (40%), Positives = 33/54 (60%), Gaps = 1/54 (1%)
Query: 273 FRAPEVLMKCSFQTQKIDIWSVGVILLSFISRRFPIFQSMDDIDAFLEICCIFG 326
+RAPEVL++ S T +D+W+VG IL + P+F +ID +ICC+ G
Sbjct: 172 YRAPEVLLQSSLYTPAVDMWAVGAILAELYALT-PLFPGESEIDQLYKICCVLG 224
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 55.1 bits (131), Expect = 2e-07
Identities = 25/54 (46%), Positives = 35/54 (64%)
Query: 128 MPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEE 181
+PI I+ YM++L +L Y+HS GI HRD+KP N L +P L DFG A++
Sbjct: 645 IPINFIRLYMYQLFRSLAYIHSLGICHRDIKPQNLLLDPETAVLKLCDFGSAKQ 698
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 54.7 bits (130), Expect = 3e-07
Identities = 45/167 (26%), Positives = 76/167 (44%), Gaps = 26/167 (15%)
Query: 22 LSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIX 81
++ ++ L+KIGEGT+ VYKA++ + ++ VA+K+I + + I
Sbjct: 1 MTESFQKLEKIGEGTYGVVYKARERNT--------------NRVVALKKIRLENENEGIP 46
Query: 82 XXXXXXXXXXXX---XXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRDMPIKG------ 132
+ L D I +++ +V Y + R + M +G
Sbjct: 47 ATTIREILLLKNLKHSTIVELSDVIYNNNKMYLVFE-YVELDLRRYLDRMSDEGRLVEEG 105
Query: 133 -IKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGL 178
++K +LL+A++Y HS I HRD+KP N L +P L DFGL
Sbjct: 106 FVRKMSQQLLTAMEYCHSRNIFHRDLKPQNILVDP-KENIKLADFGL 151
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/161 (26%), Positives = 74/161 (45%), Gaps = 23/161 (14%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
Y ++KIGEGT+ +V+KA++ + SG + VA+KR+ + +
Sbjct: 4 YDKMEKIGEGTYGTVFKARNKN--SGEI------------VALKRVRLDDDDEGVPSSAL 49
Query: 86 XXX---XXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRD----MPIKGIKKYMF 138
V L D + ++++ +V Y ++ + F+ M + + M
Sbjct: 50 REICILRELKHRNVVRLYDVVHSENKLTLVFE-YCDQDLKKFFDSLNGYMDAQTARSLML 108
Query: 139 ELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
+LL L + H+ ++HRD+KP N L N G L DFGLA
Sbjct: 109 QLLRGLSFCHAHHVLHRDLKPQNLLIN-TNGTLKLADFGLA 148
>SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase
Length = 470
Score = 54.3 bits (129), Expect = 4e-07
Identities = 43/163 (26%), Positives = 70/163 (42%), Gaps = 15/163 (9%)
Query: 22 LSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIX 81
L + + IG G + VYKA+D+ + G LY K+ + K++
Sbjct: 14 LGDSLRFVSIIGAGAYGVVYKAEDIYD--GTLYAVKALCKDGLNEKQKKLQARE------ 65
Query: 82 XXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEE-FRHFYRDMPIKG----IKKY 136
+ L + +D + VVL + P+ + F + +G IK
Sbjct: 66 --LALHARVSSHPYIITLHRVLETEDAIYVVLQYCPNGDLFTYITEKKVYQGNSHLIKTV 123
Query: 137 MFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
+L+SA+++ HS GI HRD+KP N + + L DFGLA
Sbjct: 124 FLQLISAVEHCHSVGIYHRDLKPENIMVGNDVNTVYLADFGLA 166
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 54.3 bits (129), Expect = 4e-07
Identities = 43/166 (25%), Positives = 72/166 (42%), Gaps = 23/166 (13%)
Query: 21 QLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRI 80
+++ RY + +G+GT+ V+KA D KN + VAIK+I + +
Sbjct: 6 KVADRYLKREVLGQGTYGVVFKATDT--------------KNGETVAIKKIRLGKEKEGV 51
Query: 81 XXXXXXXXXXXXXXX---VAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRDMPIK----GI 133
+ L DA +++ + +V + + RD + +
Sbjct: 52 NVTALREIKLLKELKHPHIIELIDAFPHKENLHIVFE-FMETDLEAVIRDRNLYLSPGDV 110
Query: 134 KKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
K Y+ +L L+Y H ++HRD+KP N L P G+ L DFGLA
Sbjct: 111 KSYLQMILKGLEYCHGKWVLHRDMKPNNLLIGP-NGQLKLADFGLA 155
>At4g16970 [L] KOG1167 Serine/threonine protein kinase of the CDC7 subfamily
involved in DNA synthesis repair and recombination
Length = 803
Score = 53.9 bits (128), Expect = 5e-07
Identities = 25/80 (31%), Positives = 44/80 (54%)
Query: 107 DQVVVVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNP 166
D ++L H+ R++ + ++ Y + + AL +H G++HRDVKP NFL++
Sbjct: 447 DSDCIILEHLEHDRPDSLKREIDVYQLQWYGYCMFKALSSLHKQGVVHRDVKPGNFLFSR 506
Query: 167 ILGRGVLVDFGLAEENEELY 186
+G L+DF LA + + Y
Sbjct: 507 KTNKGYLIDFNLAMDLHQKY 526
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 53.5 bits (127), Expect = 7e-07
Identities = 43/167 (25%), Positives = 77/167 (45%), Gaps = 25/167 (14%)
Query: 23 SSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXX 82
SS++K L+K+G GT+++VYK L+ +G +VA+K + + S
Sbjct: 4 SSQFKQLEKLGNGTYATVYKG--LNKTTG------------VYVALKEVKLDSEEGTPST 49
Query: 83 XXXXXXXXXXXXX--VAPLCDAIRYQDQVVVVLPWYPHEEFRHFY--------RDMPIKG 132
+ L D I ++++ +V + ++ ++ R + +
Sbjct: 50 AIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNL 109
Query: 133 IKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
+K + ++LL L + H I+HRD+KP N L N G+ L DFGLA
Sbjct: 110 VKYFQWQLLQGLAFCHENKILHRDLKPQNLLINK-RGQLKLGDFGLA 155
>CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 53.5 bits (127), Expect = 7e-07
Identities = 45/161 (27%), Positives = 71/161 (43%), Gaps = 26/161 (16%)
Query: 22 LSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSP---- 77
+S RY + +GEG F++VY AQDL ++ + VAIK+I + S
Sbjct: 1 MSRRYDTIKHLGEGQFANVYLAQDL--------------ESGECVAIKKIKLGSREEAKD 46
Query: 78 --NRIXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRDMPI----K 131
NR + L D I ++ + +V + + H +D I
Sbjct: 47 GINRTAIREIKLLKEIHHDNIIGLRDVIGHRTSIQLVFD-FMDTDLEHVIKDKEIILMPA 105
Query: 132 GIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGV 172
IK ++L L+++H I+HRD+KP N L N +GR V
Sbjct: 106 HIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNK-MGRVV 145
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 53.1 bits (126), Expect = 9e-07
Identities = 41/161 (25%), Positives = 75/161 (46%), Gaps = 22/161 (13%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
Y+ L+K+GEGT++ VYK Q+ V+G + VA+K I + +
Sbjct: 3 YQRLEKLGEGTYAHVYKGQN--RVTGEI------------VALKVIRIDADEGTPSTAIR 48
Query: 86 XXXXXXXXXX--VAPLCDAIRYQDQVVVVLPWYPHE--EFRHFYRD---MPIKGIKKYMF 138
+ L D ++ ++++++V + + ++ Y + +P +K +
Sbjct: 49 EISLMKELRHPNIMSLSDVLQTENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQ 108
Query: 139 ELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
+LL + + H ++HRD+KP N L N G L DFGLA
Sbjct: 109 QLLKGISFCHENRVLHRDLKPQNLLINS-RGELKLADFGLA 148
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 53.1 bits (126), Expect = 9e-07
Identities = 31/83 (37%), Positives = 42/83 (50%), Gaps = 6/83 (7%)
Query: 99 LCDAIRYQDQVVVV-LPWYPHEEFRHFYRDMPIKGIKKYMFELLSALKYVHSFGIIHRDV 157
LC + Y + V + WY + +P IK Y F+L AL Y+HS G+ HRD+
Sbjct: 66 LCLLLEYMPETVFDDMRWYTRRR-----KSIPNLSIKLYAFQLFRALAYLHSTGVCHRDI 120
Query: 158 KPTNFLYNPILGRGVLVDFGLAE 180
KP N L + G L DFG A+
Sbjct: 121 KPQNLLVDYKTGILKLCDFGSAK 143
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 53.1 bits (126), Expect = 9e-07
Identities = 57/194 (29%), Positives = 79/194 (40%), Gaps = 42/194 (21%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
Y L++K+GEGTF VYK+Q K+ K A+KRI + +
Sbjct: 36 YHLMEKLGEGTFGEVYKSQRR--------------KDGKVYALKRILMHTEKEGFPITAI 81
Query: 86 XXXXXXXXXX---VAPLCDAI--------RYQDQVVVVLPWYPHEEFRHFYRDMPIK--- 131
+ PL D R + + +V P+ H+ + +K
Sbjct: 82 REIKILKSIKHENIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHD-LSGLLENPSVKFTE 140
Query: 132 -GIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVL--VDFGLAEE-NEELY- 186
IK YM +L + KY+H I+HRD+K N L I G+L DFGLA EE Y
Sbjct: 141 PQIKCYMKQLFAGTKYLHDQLILHRDLKAANLL---IDNHGILKIADFGLARVITEESYA 197
Query: 187 -----LPDLNYRVY 195
LP N R Y
Sbjct: 198 NKNPGLPPPNRREY 211
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 53.1 bits (126), Expect = 9e-07
Identities = 41/160 (25%), Positives = 71/160 (43%), Gaps = 22/160 (13%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNR--IXXX 83
Y+ LDK+GEGT+++V++ + + +K VA+K I +
Sbjct: 361 YEKLDKLGEGTYATVFRGRSILT--------------NKFVALKEIRLEQEEGAPCTAIR 406
Query: 84 XXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRD----MPIKGIKKYMFE 139
V L D I + D+++ ++ Y + + + M + I+ ++++
Sbjct: 407 EVSLLRNLRHANVVTLHDII-HTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQ 465
Query: 140 LLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
LL L Y H ++HRD+KP N L G L DFGLA
Sbjct: 466 LLRGLAYCHQRRVLHRDLKPQNLLIT-AKGELKLADFGLA 504
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 53.1 bits (126), Expect = 9e-07
Identities = 41/160 (25%), Positives = 71/160 (43%), Gaps = 22/160 (13%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNR--IXXX 83
Y+ LDK+GEGT+++V++ + + +K VA+K I +
Sbjct: 238 YEKLDKLGEGTYATVFRGRSILT--------------NKFVALKEIRLEQEEGAPCTAIR 283
Query: 84 XXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRD----MPIKGIKKYMFE 139
V L D I + D+++ ++ Y + + + M + I+ ++++
Sbjct: 284 EVSLLRNLRHANVVTLHDII-HTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQ 342
Query: 140 LLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
LL L Y H ++HRD+KP N L G L DFGLA
Sbjct: 343 LLRGLAYCHQRRVLHRDLKPQNLLIT-AKGELKLADFGLA 381
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/174 (25%), Positives = 78/174 (44%), Gaps = 15/174 (8%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNR-IXXXX 84
Y D IG+G+FS V +A D + W + + V K+ V + + +
Sbjct: 54 YVFGDIIGDGSFSKVRRATDKKS----------WKEYAIKVLDKKYIVKENKVKYVNIER 103
Query: 85 XXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHF---YRDMPIKGIKKYMFELL 141
++ L + ++ VL P+ E + YR + ++ Y E+L
Sbjct: 104 DSMMRLNGFPGISRLFHTFQDDLKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEIL 163
Query: 142 SALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYRVY 195
S+++Y+HS GIIHRD+KP N L++ + + DFG A+ Y+ +Y +
Sbjct: 164 SSIEYMHSCGIIHRDLKPENILFDGNM-HVKITDFGTAKILPPKYVNSPDYTTF 216
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 52.4 bits (124), Expect = 1e-06
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 24/165 (14%)
Query: 24 SRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIY--VTSSPNRIX 81
+RY + ++G+GT+ SV + SN SG L VAIKR+ S +
Sbjct: 2 NRYTTMRQLGDGTYGSVLMGK--SNESGEL------------VAIKRMKRKFYSWDECMN 47
Query: 82 XXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRD----MPIKGIKKYM 137
V L + IR D + + Y E +D P I+ M
Sbjct: 48 LREVKSLKKLNHANVIKLKEVIRENDHLYFIFE-YMKENLYQLMKDRNKLFPESVIRNIM 106
Query: 138 FELLSALKYVHSFGIIHRDVKPTNFL-YNPILGRGVLVDFGLAEE 181
+++L L ++H G HRD+KP N L P L + + DFGLA E
Sbjct: 107 YQILQGLAFIHKHGFFHRDMKPENLLCMGPELVK--IADFGLARE 149
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 52.4 bits (124), Expect = 1e-06
Identities = 41/184 (22%), Positives = 77/184 (41%), Gaps = 13/184 (7%)
Query: 2 DDIPAEIIQEMDDLYDKVPQLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDK 61
D + II + P+ + Y +G G+F V++A+ L D+
Sbjct: 16 DQVTGHIISTTIGGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDR 75
Query: 62 NSKHVAIKRIYVTSSPNRIXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEF 121
K+ ++ + V PN + L V+ +P +
Sbjct: 76 RYKNRELQLMRVMDHPNVVCLKHCFFSTTSKDELFLNL---------VMEYVPESLYRVL 126
Query: 122 RHFY---RDMPIKGIKKYMFELLSALKYVHSF-GIIHRDVKPTNFLYNPILGRGVLVDFG 177
+H+ + MP+ +K YM+++ L Y+H+ G+ HRD+KP N L +P+ + + DFG
Sbjct: 127 KHYSSANQRMPLVYVKLYMYQIFRGLAYIHNVAGVCHRDLKPQNLLVDPLTHQVKICDFG 186
Query: 178 LAEE 181
A++
Sbjct: 187 SAKQ 190
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 52.4 bits (124), Expect = 1e-06
Identities = 39/153 (25%), Positives = 66/153 (42%), Gaps = 13/153 (8%)
Query: 32 IGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXXXXXXXX 91
+G G+F V++A+ DK K+ ++ + + PN +
Sbjct: 89 VGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKNRELQIMQMLDHPNAVALKHSFFSRTD 148
Query: 92 XXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRD---MPIKGIKKYMFELLSALKYVH 148
Y + V+ +P + R + R MP+ +K Y +++ AL Y+H
Sbjct: 149 NEEV---------YLNLVLEFVPETVNRVARSYSRTNQLMPLIYVKLYTYQICRALAYIH 199
Query: 149 -SFGIIHRDVKPTNFLYNPILGRGVLVDFGLAE 180
SFG+ HRD+KP N L NP + + DFG A+
Sbjct: 200 NSFGLCHRDIKPQNLLVNPHTHQLKICDFGSAK 232
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 52.0 bits (123), Expect = 2e-06
Identities = 40/168 (23%), Positives = 71/168 (41%), Gaps = 13/168 (7%)
Query: 17 DKVPQLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSS 76
D P+ + Y +G G+F V++A+ L DK K+ ++ + +
Sbjct: 129 DGKPKQTISYMAQRVVGTGSFGVVFQAKCLETGEQVAIKKVLQDKRYKNRELQIMRLQDH 188
Query: 77 PNRIXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYR---DMPIKGI 133
PN + Y + V+ +P + +H+ + MPI +
Sbjct: 189 PNVVRLRHSFFSTTDKDEL---------YLNLVLEYVPETVYRASKHYTKMNQHMPIIFV 239
Query: 134 KKYMFELLSALKYVHSF-GIIHRDVKPTNFLYNPILGRGVLVDFGLAE 180
+ Y +++ AL Y+H G+ HRD+KP N L NP + + DFG A+
Sbjct: 240 QLYTYQICRALNYLHRVVGVCHRDIKPQNLLVNPQTHQLKICDFGSAK 287
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 52.0 bits (123), Expect = 2e-06
Identities = 41/165 (24%), Positives = 68/165 (40%), Gaps = 13/165 (7%)
Query: 20 PQLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNR 79
P+ + Y +G G+F V++A+ L D+ K+ ++ + PN
Sbjct: 64 PKQTISYMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKNRELQLMRPMDHPNV 123
Query: 80 IXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRD---MPIKGIKKY 136
I L V+ +P + RH+ MPI +K Y
Sbjct: 124 ISLKHCFFSTTSRDELFLNL---------VMEYVPETLYRVLRHYTSSNQRMPIFYVKLY 174
Query: 137 MFELLSALKYVHSF-GIIHRDVKPTNFLYNPILGRGVLVDFGLAE 180
+++ L Y+H+ G+ HRDVKP N L +P+ + L DFG A+
Sbjct: 175 TYQIFRGLAYIHTVPGVCHRDVKPQNLLVDPLTHQVKLCDFGSAK 219
>7300288 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 630
Score = 52.0 bits (123), Expect = 2e-06
Identities = 21/53 (39%), Positives = 36/53 (67%), Gaps = 2/53 (3%)
Query: 127 DMPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
++P+ + ++++L A+ Y+H G+IH D+KP NFL + GR L+DFG+A
Sbjct: 432 NLPLYSLMNILYQMLQAVNYIHQHGVIHSDLKPANFLM--VSGRLKLIDFGIA 482
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 51.6 bits (122), Expect = 3e-06
Identities = 29/81 (35%), Positives = 43/81 (52%), Gaps = 4/81 (4%)
Query: 105 YQDQVVVVLPWYPHEEFRHFYRD---MPIKGIKKYMFELLSALKYVHSFG-IIHRDVKPT 160
Y + ++ +P ++ RHF M IK YMF+L +L Y+H F + HRD+KP
Sbjct: 109 YLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQ 168
Query: 161 NFLYNPILGRGVLVDFGLAEE 181
N L +P L DFG A++
Sbjct: 169 NLLVDPETWSLKLCDFGSAKQ 189
>CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1370
Score = 51.6 bits (122), Expect = 3e-06
Identities = 22/53 (41%), Positives = 38/53 (71%), Gaps = 1/53 (1%)
Query: 128 MPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAE 180
+P++ ++ Y+ E + A++Y+HS+GI+HRD+KP N L +G L DFGL++
Sbjct: 453 LPVELVRLYVAETILAIEYLHSYGIVHRDLKPDNLLIT-AMGHIKLTDFGLSK 504
>YOL128c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 51.2 bits (121), Expect = 3e-06
Identities = 31/71 (43%), Positives = 41/71 (57%), Gaps = 4/71 (5%)
Query: 118 HEEFRHFYRDMPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFG 177
HE F + + MP K IK Y F++L AL +HS I H D+KP+N L P G + DFG
Sbjct: 136 HEYFDNGSK-MPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFG 194
Query: 178 LA---EENEEL 185
A ++N EL
Sbjct: 195 SAQRLDDNTEL 205
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 51.2 bits (121), Expect = 3e-06
Identities = 39/165 (23%), Positives = 69/165 (41%), Gaps = 13/165 (7%)
Query: 20 PQLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNR 79
P+ + Y +G G+F V++A+ L D+ K+ ++ + + PN
Sbjct: 66 PKQTISYMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKNRELQLMRLMDHPNV 125
Query: 80 IXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRD---MPIKGIKKY 136
+ L V+ +P + +H+ MPI +K Y
Sbjct: 126 VSLKHCFFSTTTRDELFLNL---------VMEYVPETLYRVLKHYTSSNQRMPIFYVKLY 176
Query: 137 MFELLSALKYVHSF-GIIHRDVKPTNFLYNPILGRGVLVDFGLAE 180
+++ L Y+H+ G+ HRDVKP N L +P+ + L DFG A+
Sbjct: 177 TYQIFRGLAYIHTAPGVCHRDVKPQNLLVDPLTHQCKLCDFGSAK 221
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 51.2 bits (121), Expect = 3e-06
Identities = 38/161 (23%), Positives = 70/161 (42%), Gaps = 21/161 (13%)
Query: 25 RYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXX 84
+Y ++KIGEGT+ +V+K ++ + + VA+KR+ + +
Sbjct: 3 KYDKMEKIGEGTYGTVFKGRNRDTM--------------EIVALKRVRLDEDDEGVPSSA 48
Query: 85 XXXX---XXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYR---DMPIKGIKKYMF 138
+ L D + ++ +V + ++F ++ + + +M
Sbjct: 49 LREICLLKELKHKNIVRLIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFML 108
Query: 139 ELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
+LL L + HS ++HRD+KP N L N G L DFGLA
Sbjct: 109 QLLRGLAFCHSHNVLHRDLKPQNLLINK-NGELKLADFGLA 148
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 51.2 bits (121), Expect = 3e-06
Identities = 41/170 (24%), Positives = 80/170 (46%), Gaps = 30/170 (17%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
Y+ L+ IGEG + +VY+A+D+ ++G + VA+K++ ++ + N +
Sbjct: 26 YQELNIIGEGAYGTVYRARDV--ITGNI------------VALKKVRISLNENGVPMSTL 71
Query: 86 XXXXXXXXXXVA---------PLCDAIRYQDQVVVVLPW-YPHEEFRHFYRDMPIKG--- 132
+ +C + Q++++L + + ++ +P G
Sbjct: 72 REISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSP 131
Query: 133 --IKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAE 180
I++ ELL+ + ++HS IIHRD+KP N L + G + DFGLA+
Sbjct: 132 PTIQRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSS-QGHLKIADFGLAK 180
>At4g28540 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 321
Score = 50.8 bits (120), Expect = 4e-06
Identities = 29/85 (34%), Positives = 48/85 (56%), Gaps = 6/85 (7%)
Query: 105 YQDQVVVVLPWYPHEEFRHFYRDMPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLY 164
Y V+ +L + F + R + +K + +L+S ++Y+HS G +HRD+KP NFL
Sbjct: 77 YNAMVIDLLGPSLEDLFNYCNRRLTLKAVLMLADQLISRVEYMHSRGFLHRDIKPDNFLM 136
Query: 165 NPILGRGV----LVDFGLAEENEEL 185
LGR ++DFGLA++ +L
Sbjct: 137 G--LGRKANQVYIIDFGLAKKYRDL 159
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 50.8 bits (120), Expect = 4e-06
Identities = 47/162 (29%), Positives = 62/162 (38%), Gaps = 23/162 (14%)
Query: 25 RYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXX 84
RY +GEGT+ VYKA D K K VA+K+I + + +
Sbjct: 12 RYLRRQILGEGTYGVVYKATDT--------------KTGKTVAVKKIRLGNQKEGVNFTA 57
Query: 85 XXXXXXXXXXX---VAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRDMPI----KGIKKYM 137
+ L DA + + +V Y + RD I IK YM
Sbjct: 58 LREIKLLKELNHPHIVELIDAFPHDGSLHLVFE-YMQTDLEAVIRDRNIFLSPGDIKSYM 116
Query: 138 FELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
L L Y H ++HRD+KP N L G L DFGLA
Sbjct: 117 LMTLKGLAYCHKKWVLHRDMKPNNLLIGE-NGLLKLADFGLA 157
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 50.4 bits (119), Expect = 6e-06
Identities = 41/153 (26%), Positives = 69/153 (44%), Gaps = 10/153 (6%)
Query: 30 DKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXXXXXX 89
+++G G++S+V+KA D + + ++Y K K YVT N +
Sbjct: 15 EELGHGSYSTVFKALDKKSPN-KIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHA 73
Query: 90 XXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRDMPIKG---IKKYMFELLSALKY 146
+ L ++ + VL + P E M + + +L+ AL++
Sbjct: 74 G-----IIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEF 128
Query: 147 VHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
+HS GIIHRD+KP N L + GR ++ DFG A
Sbjct: 129 IHSHGIIHRDLKPENVLLDRD-GRLMITDFGAA 160
>YNL161w [R] KOG0605 NDR and related serine/threonine kinases
Length = 756
Score = 50.1 bits (118), Expect = 7e-06
Identities = 43/167 (25%), Positives = 70/167 (41%), Gaps = 24/167 (14%)
Query: 136 YMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAEENEELYLPDLNYRVY 195
YM E + A++ +H G IHRD+KP N L + I G L DFGL+ + + D NY
Sbjct: 455 YMAECILAIETIHKLGFIHRDIKPDNILID-IRGHIKLSDFGLSTGFHKTH--DSNYYKK 511
Query: 196 VNDQGEKVCNCSSPYANNKKTSHL----PLISIQNGQLNVRGANELSAAQSENLMKAELS 251
+ Q E S P N T+ + + + L + ++ + + A +
Sbjct: 512 LLQQDEATNGISKPGTYNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRLMAYST 571
Query: 252 KGYPKHEXXXXXXXXXXXXXXFRAPEVLMKCSFQTQKIDIWSVGVIL 298
G P + APE+ + + Q+ D WS+G I+
Sbjct: 572 VGTP----------------DYIAPEIFLYQGY-GQECDWWSLGAIM 601
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 50.1 bits (118), Expect = 7e-06
Identities = 36/156 (23%), Positives = 71/156 (45%), Gaps = 13/156 (8%)
Query: 26 YKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRIXXXXX 85
Y+++ +GEG+F V A Y K + + K++ S
Sbjct: 55 YQIVKTLGEGSFGKVKLA----------YHTTTGQKVALKIINKKVLAKSDMQGRIEREI 104
Query: 86 XXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYR--DMPIKGIKKYMFELLSA 143
+ L D I+ +D++++V+ + +E F + + M + +++ +++SA
Sbjct: 105 SYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISA 164
Query: 144 LKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLA 179
++Y H I+HRD+KP N L + L + DFGL+
Sbjct: 165 VEYCHRHKIVHRDLKPENLLLDEHLNVKI-ADFGLS 199
>Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1734
Score = 50.1 bits (118), Expect = 7e-06
Identities = 22/53 (41%), Positives = 36/53 (67%), Gaps = 1/53 (1%)
Query: 128 MPIKGIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYNPILGRGVLVDFGLAE 180
+P+ ++ Y E + AL+Y+H++GI+HRD+KP N L +G L DFGL++
Sbjct: 607 LPVDMVRLYFAETVLALEYLHNYGIVHRDLKPDNLLITS-MGHIKLTDFGLSK 658
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 50.1 bits (118), Expect = 7e-06
Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 5/84 (5%)
Query: 273 FRAPEVLMKCSFQTQKIDIWSVGVILLSFISRRFPIFQSMDDIDAFLEICCIFGIKPMQE 332
+RAPEVL++ T K+D+W++G I+ +S R P+F + D +IC + G P +E
Sbjct: 172 YRAPEVLLQSYVYTSKVDMWAMGAIMAELLSLR-PLFPGASEADEIYKICSVIG-SPTEE 229
Query: 333 VAKFHGLGLDMTKVPGFHSEGYPG 356
GL++ V + +PG
Sbjct: 230 TWL---EGLNLASVINYQFPQFPG 250
>SPBC3H7.15 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 365
Score = 49.7 bits (117), Expect = 1e-05
Identities = 42/164 (25%), Positives = 73/164 (43%), Gaps = 15/164 (9%)
Query: 21 QLSSRYKLLDKIGEGTFSSVYKAQDLSNVSGRLYPDHFWDKNSKHVAIKRIYVTSSPNRI 80
++ ++Y++ KIG G+F +Y ++ VSG +KH ++ Y R+
Sbjct: 6 RIGNKYRIGRKIGSGSFGDIYLGTNV--VSGEEVAIKLESTRAKHPQLEYEY------RV 57
Query: 81 XXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRDMPIKGIKKYMFEL 140
CD Y V+ +L + F R +K + +L
Sbjct: 58 YRILSGGVGIPFVRWFGVECD---YNAMVMDLLGPSLEDLFNFCNRKFSLKTVLLLADQL 114
Query: 141 LSALKYVHSFGIIHRDVKPTNFLYNPILGRG---VLVDFGLAEE 181
+S ++++HS +HRD+KP NFL I RG ++DFGLA++
Sbjct: 115 ISRIEFIHSKSFLHRDIKPDNFLMG-IGKRGNQVNIIDFGLAKK 157
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 49.7 bits (117), Expect = 1e-05
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 7/85 (8%)
Query: 103 IRYQDQVVVVLPWYPHEEFRHFYRDMPIKG--IKKYMFELLSALKYVHSFGIIHRDVKPT 160
I Y +++ VV + + P+ +K +++++L LKY+HS GI+HRD+KP
Sbjct: 197 IDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPG 256
Query: 161 NFLYNP--ILGRGVLVDFGLAEENE 183
N L N +L + DFGLA E
Sbjct: 257 NLLVNSNCVL---KICDFGLARVEE 278
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 49.7 bits (117), Expect = 1e-05
Identities = 44/171 (25%), Positives = 73/171 (41%), Gaps = 36/171 (21%)
Query: 24 SRYKLLDKIGEGTFSSVYKAQD--------LSNVSGRLYPDHFWDKNSKHVAIKRIYVTS 75
+RY L ++G+GT+ +V Q + + + Y W++ +K + S
Sbjct: 2 NRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYS---WEEAMNLREVKSLKKLS 58
Query: 76 SPNRIXXXXXXXXXXXXXXXVAPLCDAIRYQDQVVVVLPWYPHEEFRHFYRD----MPIK 131
PN + L + IR D + V Y E +D +P
Sbjct: 59 HPN-----------------IVKLKEVIRENDTLYFVFE-YMKENLYQMIKDRDTHLPEP 100
Query: 132 GIKKYMFELLSALKYVHSFGIIHRDVKPTNFLYN-PILGRGVLVDFGLAEE 181
+K +F++L+ L ++H G HRD+KP N L + P L + + DFGLA E
Sbjct: 101 ELKSILFQVLTGLAFMHRHGFFHRDLKPENLLCSGPDLIK--IADFGLARE 149
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.140 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,661,244
Number of Sequences: 60738
Number of extensions: 1196161
Number of successful extensions: 6747
Number of sequences better than 1.0e-05: 82
Number of HSP's better than 0.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 6545
Number of HSP's gapped (non-prelim): 191
length of query: 475
length of database: 30,389,216
effective HSP length: 110
effective length of query: 365
effective length of database: 23,708,036
effective search space: 8653433140
effective search space used: 8653433140
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)