ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1136 good A KOG1596 RNA processing and modification Fibrillarin and related nucleolar RNA-binding proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1136 401421 402425 335
(335 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL014w [A] KOG1596 Fibrillarin and related nucleolar RNA-bindin... 465 e-131
SPBC2D10.10c [A] KOG1596 Fibrillarin and related nucleolar RNA-b... 384 e-106
At5g52470 [A] KOG1596 Fibrillarin and related nucleolar RNA-bind... 350 2e-96
Hs12056465 [A] KOG1596 Fibrillarin and related nucleolar RNA-bin... 349 4e-96
At4g25630 [A] KOG1596 Fibrillarin and related nucleolar RNA-bind... 349 4e-96
7291525 [A] KOG1596 Fibrillarin and related nucleolar RNA-bindin... 341 1e-93
CE12920 [A] KOG1596 Fibrillarin and related nucleolar RNA-bindin... 337 1e-92
ECU10g0820 [A] KOG1596 Fibrillarin and related nucleolar RNA-bin... 305 8e-83
At5g52490 [A] KOG1596 Fibrillarin and related nucleolar RNA-bind... 273 3e-73
7299687 [A] KOG1596 Fibrillarin and related nucleolar RNA-bindin... 182 8e-46
>YDL014w [A] KOG1596 Fibrillarin and related nucleolar RNA-binding proteins
Length = 327
Score = 465 bits (1197), Expect = e-131
Identities = 229/241 (95%), Positives = 239/241 (99%)
Query: 95 KVVIEPHKHAGVFIARGKEDLLVTKNIAPGESVYGEKRVSVEEPSTEEGVPPTKVEYRVW 154
KVVIEPH+HAGV+IARGKEDLLVTKN+APGESVYGEKR+SVEEPS E+GVPPTKVEYRVW
Sbjct: 85 KVVIEPHRHAGVYIARGKEDLLVTKNMAPGESVYGEKRISVEEPSKEDGVPPTKVEYRVW 144
Query: 155 NPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGLVYAVEFSHRPG 214
NPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEG+VYAVEFSHRPG
Sbjct: 145 NPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRPG 204
Query: 215 RELISMAKKRPNVIPIIEDARHPQKYRMLIGMVDAVFADVAQPDQARIIALNSHMFLKDQ 274
RELISMAKKRPN+IPIIEDARHPQKYRMLIGMVD VFADVAQPDQARIIALNSHMFLKDQ
Sbjct: 205 RELISMAKKRPNIIPIIEDARHPQKYRMLIGMVDCVFADVAQPDQARIIALNSHMFLKDQ 264
Query: 275 GGVVISIKANCIDSTVDAETVFAREVQKLREEKIKPLEQLTLEPYERDHCIVIGKYMRSG 334
GGVVISIKANCIDSTVDAETVFAREVQKLREE+IKPLEQLTLEPYERDHCIV+G+YMRSG
Sbjct: 265 GGVVISIKANCIDSTVDAETVFAREVQKLREERIKPLEQLTLEPYERDHCIVVGRYMRSG 324
Query: 335 L 335
L
Sbjct: 325 L 325
>SPBC2D10.10c [A] KOG1596 Fibrillarin and related nucleolar RNA-binding proteins
Length = 305
Score = 384 bits (985), Expect = e-106
Identities = 185/238 (77%), Positives = 214/238 (89%), Gaps = 6/238 (2%)
Query: 95 KVVIEPHKHAGVFIARGKEDLLVTKNIAPGESVYGEKRVSVEEPSTEEGVPPTKVEYRVW 154
KV+IEPH+HAGVFIARGKEDLLVT+N+ PGESVY EKR+SV+ P TKVEYRVW
Sbjct: 72 KVIIEPHRHAGVFIARGKEDLLVTRNLVPGESVYNEKRISVDSPDG------TKVEYRVW 125
Query: 155 NPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGLVYAVEFSHRPG 214
NPFRSKLAAGI+GGLD ++I PG +VLYLGAA+GTSVSHV+DVVGPEGLVYAVEFSHR G
Sbjct: 126 NPFRSKLAAGILGGLDNIYIKPGARVLYLGAANGTSVSHVADVVGPEGLVYAVEFSHRSG 185
Query: 215 RELISMAKKRPNVIPIIEDARHPQKYRMLIGMVDAVFADVAQPDQARIIALNSHMFLKDQ 274
R+L++MAKKR NVIPI+EDARH QKYRML+GMVD VFADVAQPDQARI+ALN+ FLK++
Sbjct: 186 RDLLNMAKKRTNVIPIVEDARHVQKYRMLVGMVDVVFADVAQPDQARIVALNAAAFLKNE 245
Query: 275 GGVVISIKANCIDSTVDAETVFAREVQKLREEKIKPLEQLTLEPYERDHCIVIGKYMR 332
GGVVIS+KA+CIDST DA VFAREV+K++EEKIKP EQLTLEPYERDHCI++GKY+R
Sbjct: 246 GGVVISVKASCIDSTADAAVVFAREVKKMQEEKIKPQEQLTLEPYERDHCIIVGKYLR 303
>At5g52470 [A] KOG1596 Fibrillarin and related nucleolar RNA-binding proteins
Length = 308
Score = 350 bits (898), Expect = 2e-96
Identities = 172/236 (72%), Positives = 202/236 (84%), Gaps = 6/236 (2%)
Query: 95 KVVIEPHKHAGVFIARGKEDLLVTKNIAPGESVYGEKRVSVEEPSTEEGVPPTKVEYRVW 154
KV++EPH+HAGVFIA+GKED LVTKN+ PGE+VY EKR+SV+ E+G TKVEYRVW
Sbjct: 68 KVIVEPHRHAGVFIAKGKEDALVTKNLVPGEAVYNEKRISVQN---EDG---TKVEYRVW 121
Query: 155 NPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGLVYAVEFSHRPG 214
NPFRSKLAA I+GG+D ++I PG KVLYLGAASGT+VSHVSD+VGPEG VYAVEFSHR G
Sbjct: 122 NPFRSKLAAAILGGVDNIWIKPGAKVLYLGAASGTTVSHVSDLVGPEGCVYAVEFSHRSG 181
Query: 215 RELISMAKKRPNVIPIIEDARHPQKYRMLIGMVDAVFADVAQPDQARIIALNSHMFLKDQ 274
R+L++MAKKR NVIPIIEDARHP KYRML+GMVD +F+DVAQPDQARI+ALN+ FLK
Sbjct: 182 RDLVNMAKKRTNVIPIIEDARHPAKYRMLVGMVDVIFSDVAQPDQARILALNASFFLKTG 241
Query: 275 GGVVISIKANCIDSTVDAETVFAREVQKLREEKIKPLEQLTLEPYERDHCIVIGKY 330
G VISIKANCIDSTV AE VF EV+KL++E+ KP EQ+TLEP+ERDH V+G Y
Sbjct: 242 GHFVISIKANCIDSTVAAEAVFQSEVKKLQQEQFKPAEQVTLEPFERDHACVVGGY 297
>Hs12056465 [A] KOG1596 Fibrillarin and related nucleolar RNA-binding proteins
Length = 321
Score = 349 bits (895), Expect = 4e-96
Identities = 167/235 (71%), Positives = 197/235 (83%), Gaps = 7/235 (2%)
Query: 96 VVIEPHKHAGVFIARGKEDLLVTKNIAPGESVYGEKRVSVEEPSTEEGVPPTKVEYRVWN 155
V++EPH+H GVFI RGKED LVTKN+ PGESVYGEKRVS+ E K+EYR WN
Sbjct: 86 VMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDD-------KIEYRAWN 138
Query: 156 PFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGLVYAVEFSHRPGR 215
PFRSKLAA I+GG+D++ I PG KVLYLGAASGT+VSHVSD+VGP+GLVYAVEFSHR GR
Sbjct: 139 PFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGR 198
Query: 216 ELISMAKKRPNVIPIIEDARHPQKYRMLIGMVDAVFADVAQPDQARIIALNSHMFLKDQG 275
+LI++AKKR N+IP+IEDARHP KYRMLI MVD +FADVAQPDQ RI+ALN+H FL++ G
Sbjct: 199 DLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGG 258
Query: 276 GVVISIKANCIDSTVDAETVFAREVQKLREEKIKPLEQLTLEPYERDHCIVIGKY 330
VISIKANCIDST AE VFA EV+K+++E +KP EQLTLEPYERDH +V+G Y
Sbjct: 259 HFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVY 313
>At4g25630 [A] KOG1596 Fibrillarin and related nucleolar RNA-binding proteins
Length = 320
Score = 349 bits (895), Expect = 4e-96
Identities = 171/236 (72%), Positives = 201/236 (84%), Gaps = 6/236 (2%)
Query: 95 KVVIEPHKHAGVFIARGKEDLLVTKNIAPGESVYGEKRVSVEEPSTEEGVPPTKVEYRVW 154
KV++EPH+HAGVFIA+GKED LVTKN+ PGE+VY EKR+SV+ E+G TK EYRVW
Sbjct: 79 KVIVEPHRHAGVFIAKGKEDALVTKNLVPGEAVYNEKRISVQN---EDG---TKTEYRVW 132
Query: 155 NPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGLVYAVEFSHRPG 214
NPFRSKLAA I+GG+D ++I PG KVLYLGAASGT+VSHVSD+VGPEG VYAVEFSHR G
Sbjct: 133 NPFRSKLAAAILGGVDNIWIKPGAKVLYLGAASGTTVSHVSDLVGPEGCVYAVEFSHRSG 192
Query: 215 RELISMAKKRPNVIPIIEDARHPQKYRMLIGMVDAVFADVAQPDQARIIALNSHMFLKDQ 274
R+L++MAKKR NVIPIIEDARHP KYRML+GMVD +F+DVAQPDQARI+ALN+ FLK
Sbjct: 193 RDLVNMAKKRTNVIPIIEDARHPAKYRMLVGMVDVIFSDVAQPDQARILALNASYFLKSG 252
Query: 275 GGVVISIKANCIDSTVDAETVFAREVQKLREEKIKPLEQLTLEPYERDHCIVIGKY 330
G VISIKANCIDSTV AE VF EV+KL++E+ KP EQ+TLEP+ERDH V+G Y
Sbjct: 253 GHFVISIKANCIDSTVPAEAVFQTEVKKLQQEQFKPAEQVTLEPFERDHACVVGGY 308
>7291525 [A] KOG1596 Fibrillarin and related nucleolar RNA-binding proteins
Length = 344
Score = 341 bits (874), Expect = 1e-93
Identities = 165/235 (70%), Positives = 194/235 (82%), Gaps = 7/235 (2%)
Query: 96 VVIEPHKHAGVFIARGKEDLLVTKNIAPGESVYGEKRVSVEEPSTEEGVPPTKVEYRVWN 155
V IEPH+H GVFIARGKED LVT+N PG VYGEKR+SVE K+EYRVWN
Sbjct: 111 VTIEPHRHEGVFIARGKEDALVTRNFVPGSEVYGEKRISVETNGE-------KIEYRVWN 163
Query: 156 PFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGLVYAVEFSHRPGR 215
PFRSKLAA ++GG++++ + PG KVLYLGAASGT+VSHVSDVVGPEGLVYAVEFSHR GR
Sbjct: 164 PFRSKLAAAVLGGVEQIHMPPGSKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGR 223
Query: 216 ELISMAKKRPNVIPIIEDARHPQKYRMLIGMVDAVFADVAQPDQARIIALNSHMFLKDQG 275
+LI++AKKR N+IPIIEDARHP KYRML+GMVD +FADVAQPDQ RI+ALN+ FLK+ G
Sbjct: 224 DLINVAKKRTNIIPIIEDARHPHKYRMLVGMVDTIFADVAQPDQGRIVALNAQHFLKNGG 283
Query: 276 GVVISIKANCIDSTVDAETVFAREVQKLREEKIKPLEQLTLEPYERDHCIVIGKY 330
VISIKA+CIDST E VFA EV+K++ +K+KP EQLTLEPYERDH +V+G Y
Sbjct: 284 HFVISIKASCIDSTAQPEAVFAAEVKKMQADKLKPQEQLTLEPYERDHAVVVGVY 338
>CE12920 [A] KOG1596 Fibrillarin and related nucleolar RNA-binding proteins
Length = 352
Score = 337 bits (865), Expect = 1e-92
Identities = 164/235 (69%), Positives = 193/235 (81%), Gaps = 7/235 (2%)
Query: 96 VVIEPHKHAGVFIARGKEDLLVTKNIAPGESVYGEKRVSVEEPSTEEGVPPTKVEYRVWN 155
VV+EPH+ GVFI +GKED L TKN+ GESVYGEKRVSV++ + +EYRVWN
Sbjct: 117 VVVEPHRLGGVFIVKGKEDALATKNMVVGESVYGEKRVSVDDGAGS-------IEYRVWN 169
Query: 156 PFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGLVYAVEFSHRPGR 215
PFRSKLAA IMGGL+ I PG K+LYLGAASGT+VSH SDVVGPEG+VYAVEFSHR GR
Sbjct: 170 PFRSKLAASIMGGLENTHIKPGTKLLYLGAASGTTVSHCSDVVGPEGIVYAVEFSHRSGR 229
Query: 216 ELISMAKKRPNVIPIIEDARHPQKYRMLIGMVDAVFADVAQPDQARIIALNSHMFLKDQG 275
+L+ +AKKRPNV+PI+EDARHP KYRML+GMVD +F+DVAQPDQARI+ALN+ FL++ G
Sbjct: 230 DLLGVAKKRPNVVPIVEDARHPHKYRMLVGMVDVIFSDVAQPDQARIVALNAQNFLRNGG 289
Query: 276 GVVISIKANCIDSTVDAETVFAREVQKLREEKIKPLEQLTLEPYERDHCIVIGKY 330
VISIKANCIDST + E VFA EV KL+EEK KPLEQ+TLEPYERDH +V+ Y
Sbjct: 290 HAVISIKANCIDSTAEPEAVFAGEVNKLKEEKFKPLEQVTLEPYERDHAVVVAVY 344
>ECU10g0820 [A] KOG1596 Fibrillarin and related nucleolar RNA-binding proteins
Length = 291
Score = 305 bits (780), Expect = 8e-83
Identities = 149/240 (62%), Positives = 197/240 (82%), Gaps = 8/240 (3%)
Query: 95 KVVIEPH-KHAGVFIARGKEDLLVTKNIAPGESVYGEKRVSVEEPSTEEGVPPTKVEYRV 153
KV++EPH + GV+I+RGKEDLL+T+N+ PG SVYGEKRV+V+ EG+ KVEYRV
Sbjct: 46 KVLVEPHPRFPGVYISRGKEDLLLTRNLVPGVSVYGEKRVAVDL----EGM---KVEYRV 98
Query: 154 WNPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGLVYAVEFSHRP 213
WN +RSKLAAGI+ G + + + PG KVLYLGA+SGT+VSHVSD+VG +G+VYAVEFS R
Sbjct: 99 WNAYRSKLAAGIVCGAENIHMEPGSKVLYLGASSGTTVSHVSDIVGKDGVVYAVEFSERS 158
Query: 214 GRELISMAKKRPNVIPIIEDARHPQKYRMLIGMVDAVFADVAQPDQARIIALNSHMFLKD 273
GR+LI+M+ KRPN++PIIEDAR+P +YRML+ +VD +F+DV+QPDQ RI+ALN+ FLK+
Sbjct: 159 GRDLINMSMKRPNIVPIIEDARYPSRYRMLVPIVDCIFSDVSQPDQTRIVALNAQYFLKE 218
Query: 274 QGGVVISIKANCIDSTVDAETVFAREVQKLREEKIKPLEQLTLEPYERDHCIVIGKYMRS 333
GGV +SIKANC++S V AETVFA EV LR+ I+P EQ+TLEP+E+DH ++IG++ S
Sbjct: 219 GGGVDVSIKANCVNSAVPAETVFADEVNILRKNSIRPKEQVTLEPFEKDHAMIIGRFKLS 278
>At5g52490 [A] KOG1596 Fibrillarin and related nucleolar RNA-binding proteins
Length = 292
Score = 273 bits (698), Expect = 3e-73
Identities = 138/236 (58%), Positives = 174/236 (73%), Gaps = 6/236 (2%)
Query: 95 KVVIEPHKHAGVFIARGKEDLLVTKNIAPGESVYGEKRVSVEEPSTEEGVPPTKVEYRVW 154
KV++ PH+HAGVF+A+ K D LVTKN+ PGE +Y EKR+ V+ + VEYRVW
Sbjct: 58 KVLVTPHRHAGVFVAKSKADALVTKNLVPGEIIYNEKRIFVQNEDR------STVEYRVW 111
Query: 155 NPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGLVYAVEFSHRPG 214
NP RSKLA I G+D ++I PG KVLYLGA+SG +VSHVSD+VGPEG VYAVE S G
Sbjct: 112 NPHRSKLADAITTGVDNIWIKPGVKVLYLGASSGYTVSHVSDIVGPEGCVYAVEHSDICG 171
Query: 215 RELISMAKKRPNVIPIIEDARHPQKYRMLIGMVDAVFADVAQPDQARIIALNSHMFLKDQ 274
+ L++MA+KR NVIPIIEDARHP KYRML+GMVD +F+DV P+QA I++LN+ FLK
Sbjct: 172 KVLMNMAEKRTNVIPIIEDARHPAKYRMLVGMVDIIFSDVNHPEQANILSLNASYFLKSG 231
Query: 275 GGVVISIKANCIDSTVDAETVFAREVQKLREEKIKPLEQLTLEPYERDHCIVIGKY 330
G +ISIKAN IDST+ AETV+ EV+KL+ E+++P E L L+ E H V G Y
Sbjct: 232 GHFMISIKANSIDSTIAAETVYQMEVEKLQMEELRPTEILHLDSCEEKHACVFGGY 287
>7299687 [A] KOG1596 Fibrillarin and related nucleolar RNA-binding proteins
Length = 349
Score = 182 bits (461), Expect = 8e-46
Identities = 100/238 (42%), Positives = 144/238 (60%), Gaps = 10/238 (4%)
Query: 98 IEPHKHAGVFIARGKEDL--LVTKNIAPGESVYGEKRVSVEEPSTEEGVPPTKVEYRVWN 155
IEPH+H GV++ R + D L+T+N + YGE+RV E + E+RVW+
Sbjct: 114 IEPHRHYGVYLLRNRFDAIQLLTRNTSSSADDYGERRVISEYREM-------RCEFRVWS 166
Query: 156 PFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGLVYAVEFSHRPGR 215
PF+SKLAAGIMGG+ +L + G KVLYLGA G SVSH+SD+VG G+VYAVE GR
Sbjct: 167 PFQSKLAAGIMGGVSDLHLQIGSKVLYLGAGFGRSVSHISDIVGDSGMVYAVEQIPWAGR 226
Query: 216 ELISMAKKRPNVIPIIEDARHPQKYRMLI-GMVDAVFADVAQPDQARIIALNSHMFLKDQ 274
+L MA +R N++PI+EDA P KYR + +D +FAD+ R + LN+ FL
Sbjct: 227 QLTIMANRRSNIVPIVEDATMPYKYRYEVPACIDIIFADLPPSVLIRALMLNARHFLNPG 286
Query: 275 GGVVISIKANCIDSTVDAETVFAREVQKLREEKIKPLEQLTLEPYERDHCIVIGKYMR 332
G V + + V + FA E + L+E++++P E + LEP++ + V+G Y+R
Sbjct: 287 GHFVAYLHSPTSQGVVFNKDSFAAERRLLKEKQLEPKEMVLLEPFKAGYAFVVGVYIR 344
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.137 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,414,942
Number of Sequences: 60738
Number of extensions: 588925
Number of successful extensions: 1544
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1523
Number of HSP's gapped (non-prelim): 10
length of query: 335
length of database: 30,389,216
effective HSP length: 107
effective length of query: 228
effective length of database: 23,890,250
effective search space: 5446977000
effective search space used: 5446977000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)