ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1148 good R KOG3912 General function prediction only Predicted integral membrane protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1148 405523 406623 367
(367 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPAC12G12.12 [R] KOG3912 Predicted integral membrane protein 169 5e-42
CE02516 [R] KOG3912 Predicted integral membrane protein 137 3e-32
Hs8923524 [R] KOG3912 Predicted integral membrane protein 129 9e-30
7299540 [R] KOG3912 Predicted integral membrane protein 85 2e-16
>SPAC12G12.12 [R] KOG3912 Predicted integral membrane protein
Length = 324
Score = 169 bits (429), Expect = 5e-42
Identities = 105/307 (34%), Positives = 160/307 (51%), Gaps = 16/307 (5%)
Query: 13 LIVTGCINSIATKYQDNQCVRDCDSISPVLFEQPVLQTLQMFIGEISLMFVMFWQKYNSR 72
++ +G N++ +KYQD+ S + VLQ+L +F+GE L F + +++++
Sbjct: 7 MLTSGVANTVLSKYQDSIAEE-----SEPIKSMAVLQSLNIFLGEACLWFYVLYKRHSQG 61
Query: 73 NGYEAVPSAESLNKTKLPSRQSYALALPAICDICGTTLMNLALTMIPVSIYQMTRGVLIL 132
GYE++ LP + +ALPAI DICG+TLMN+ L SIYQMTRG LI+
Sbjct: 62 PGYESLDH--------LPLKHKVFMALPAIMDICGSTLMNVGLLYTSASIYQMTRGSLII 113
Query: 133 FVALFSVFFLKHKISRFEWLSXXXXXXXXXXXXYSGNVGVTVDVSLVTGVLLIVLAQVCT 192
FVALF+ LK I + +WLS YSG+ ++ + + G+ +++ Q
Sbjct: 114 FVALFATTLLKRTIGQLQWLSLSFVVLGVAIVGYSGS-SSSIGSNPILGITAVLIGQFFL 172
Query: 193 ATQFVLEEHIMSKWIIPPSTLVAFEGIYGASITLLTMLIASVTFAQNK--QNSSFNIVYS 250
ATQF +EE+I+S + PS LVA+EG YG LL M+I+ + F+ +
Sbjct: 173 ATQFTIEEYILSFIQVDPSELVAYEGTYGVFFVLLGMIISYYFIGSTTAGYHGWFDYSHV 232
Query: 251 LQDMFVNPRVLYSSIIIMISIACFNFFGITLTNSMNATVRSTIDTCRTXXXXXXXXXXXX 310
+ P + S +I++SIA FN G+ +T +AT RS +D RT
Sbjct: 233 ISRFNEVPALYVISGVILVSIAFFNVSGLAITKLHSATTRSLLDIARTFGIWIIAMAMGM 292
Query: 311 ESFKLTQ 317
ESF L Q
Sbjct: 293 ESFHLLQ 299
>CE02516 [R] KOG3912 Predicted integral membrane protein
Length = 393
Score = 137 bits (345), Expect = 3e-32
Identities = 89/311 (28%), Positives = 150/311 (47%), Gaps = 26/311 (8%)
Query: 7 IVTALSLIVTGCINSIATKYQDNQCVRDCDSISPVLFEQPVLQTLQMFIGEISLMFVMF- 65
++ ++ ++VTG +N+I K+ D+ V F P LQ MF GE + V F
Sbjct: 6 VIISVMMVVTGSLNTICAKWADSI------KADGVPFNHPFLQATCMFFGEFLCLVVFFL 59
Query: 66 --------WQKYNSRNGYEAVPSAESLNKTKLPSRQSYALALPAICDICGTTLMNLALTM 117
W + N + +V S K LP + PA+CDI GT++M + L +
Sbjct: 60 IFGYKRYVWNRANVQGESGSVTEITSEEKPTLPPFNPFLFFPPALCDILGTSIMYIGLNL 119
Query: 118 IPVSIYQMTRGVLILFVALFSVFFLKHKISRFEWLS----XXXXXXXXXXXXYSGNVGVT 173
S +QM RG +I+F L SV L +I F+W Y + +
Sbjct: 120 TTASSFQMLRGAVIIFTGLLSVGMLNAQIKPFKWFGMLFVMLGLVIVGVTDIYYDDDPLD 179
Query: 174 VDVSLVTGVLLIVLAQVCTATQFVLEEHIMSKWIIPPSTLVAFEGIYGASITLLTMLI-- 231
+++TG LLIV+AQ+ A Q V E+ ++K+ +P V EG++G +TL ++I
Sbjct: 180 DKNAIITGNLLIVMAQIIVAIQMVYEQKYLTKYDVPALFAVGLEGLFG-MVTLSILMIPF 238
Query: 232 ----ASVTFAQNKQNSSFNIVYSLQDMFVNPRVLYSSIIIMISIACFNFFGITLTNSMNA 287
TF+ N + ++ Y+ +++ P + + ++SIA FNF G+++T ++A
Sbjct: 239 YYIHVPRTFSTNPEGRLEDVFYAWKEITEEPTIALALSGTVVSIAFFNFAGVSVTKELSA 298
Query: 288 TVRSTIDTCRT 298
T R +D+ RT
Sbjct: 299 TTRMVLDSVRT 309
>Hs8923524 [R] KOG3912 Predicted integral membrane protein
Length = 371
Score = 129 bits (323), Expect = 9e-30
Identities = 91/313 (29%), Positives = 149/313 (47%), Gaps = 15/313 (4%)
Query: 13 LIVTGCINSIATKYQDNQCVRDCDSISPVLFEQPVLQTLQMFIGEISLMFVMFWQKYNSR 72
++VTG IN+++ K+ DN C F+ P LQ + MF+GE S + + +
Sbjct: 14 MLVTGSINTLSAKWADNFMAEGCGGSKEHSFQHPFLQAVGMFLGEFSCLAAFYLLRCR-- 71
Query: 73 NGYEAVPSAESLNKTKLPSRQSYALALPAICDICGTTLMNLALTMIPVSIYQMTRGVLIL 132
A ++S + P L PA+CD+ GT+LM +AL M S +QM RG +I+
Sbjct: 72 ----AAGQSDSSVDPQQPFNPLLFLP-PALCDMTGTSLMYVALNMTSASSFQMLRGAVII 126
Query: 133 FVALFSVFFLKHKISRFEWLSXXXXXX----XXXXXXYSGNVGVTVDVSLVTGVLLIVLA 188
F LFSV FL ++ +WL S + ++TG LLI++A
Sbjct: 127 FTGLFSVAFLGRRLVLSQWLGILATIAGLVVVGLADLLSKHDSQHKLSEVITGDLLIIMA 186
Query: 189 QVCTATQFVLEEHIMSKWIIPPSTLVAFEGIYGASITLLTML----IASVTFAQNKQNSS 244
Q+ A Q VLEE + K + P V +G++G I L ++ I + +F+ N + +
Sbjct: 187 QIIVAIQMVLEEKFVYKHNVHPLRAVGTKGLFGFVILSLLLVPMYYIPAGSFSGNPRGTL 246
Query: 245 FNIVYSLQDMFVNPRVLYSSIIIMISIACFNFFGITLTNSMNATVRSTIDTCRTXXXXXX 304
+ + + + P + + + + SIA FNF GI++T ++AT R +D+ RT
Sbjct: 247 EDALDAFCQVGQQPLIAVALLGNISSIAFFNFAGISVTKELSATTRMVLDSLRTVVIWAL 306
Query: 305 XXXXXXESFKLTQ 317
E+F Q
Sbjct: 307 SLALGWEAFHALQ 319
>7299540 [R] KOG3912 Predicted integral membrane protein
Length = 381
Score = 84.7 bits (208), Expect = 2e-16
Identities = 72/305 (23%), Positives = 132/305 (42%), Gaps = 16/305 (5%)
Query: 7 IVTALSLIVTGCINSIATKYQDNQCVRDCDSISPVLFEQPVLQTLQMFIGEISLMFVMFW 66
+ +L +++G N + K+ + Q V D F+ PV+ TL MF+GE L F +F
Sbjct: 5 VFLSLIFVLSGTFNVLVVKWANQQQVIGSDGKLHG-FQHPVVFTLLMFLGEF-LCFAVFK 62
Query: 67 QKYNSRNGYEAVPSAESLNKTKLPSRQSYALALPAICDICGTTLMNLALTMIPVSIYQMT 126
N + +S+ + ++ LP + D + L+ L + + +QM
Sbjct: 63 VIRLISNRRGVISDLDSILSQDSSEFRPVSMLLPTLLDAAASILLFTGLYLTYATSFQMI 122
Query: 127 RGVLILFVALFSVFFLKHKISRFEWLSXXXXXXXXXXXXYSGNVGVTVDV---------S 177
RG ++FV +FS FL H ++ WL+ V D+ S
Sbjct: 123 RGAALIFVGIFSTMFLNHTLTGRHWLAIFTISCGLLDIISLDVHRVEYDLVTLPYTDYKS 182
Query: 178 LVTGVLLIVLAQVCTATQFVLEEHIMSKWIIPPSTLVAFEGIYGASITLLTMLIASVTFA 237
++TG LLI++A++ Q+V EE + + P ++GI+G IT + + + +
Sbjct: 183 ILTGDLLIIIAEILHGLQYVCEEKQLKTSNVAPLQAAGWQGIFGLGITSMLAICMNFLPS 242
Query: 238 QNKQNSSFNIVY-SLQDMFV----NPRVLYSSIIIMISIACFNFFGITLTNSMNATVRST 292
+ + S V+ D+F + ++ + I IS A +NF G+ + ++ R
Sbjct: 243 IDPFSCSSRAVFDDWGDLFAALQGSISLIMTLIAFTISCAMYNFIGLYIAMYSSSANRLL 302
Query: 293 IDTCR 297
D R
Sbjct: 303 ADGLR 307
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.326 0.138 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,968,348
Number of Sequences: 60738
Number of extensions: 563109
Number of successful extensions: 1870
Number of sequences better than 1.0e-05: 4
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1854
Number of HSP's gapped (non-prelim): 4
length of query: 367
length of database: 30,389,216
effective HSP length: 108
effective length of query: 259
effective length of database: 23,829,512
effective search space: 6171843608
effective search space used: 6171843608
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)