ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1166 good O KOG3313 Posttranslational modification, protein turnover, chaperones Molecular chaperone Prefoldin, subunit 3
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1166 413587 414177 197
(197 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR078c [O] KOG3313 Molecular chaperone Prefoldin subunit 3 253 1e-67
Hs4507873 [O] KOG3313 Molecular chaperone Prefoldin subunit 3 139 2e-33
SPAC3H8.07c [O] KOG3313 Molecular chaperone Prefoldin subunit 3 135 3e-32
At5g49510 [O] KOG3313 Molecular chaperone Prefoldin subunit 3 123 2e-28
7299441 [O] KOG3313 Molecular chaperone Prefoldin subunit 3 120 1e-27
CE13349 [O] KOG3313 Molecular chaperone Prefoldin subunit 3 92 5e-19
7291320 [O] KOG3313 Molecular chaperone Prefoldin subunit 3 50 2e-06
>YGR078c [O] KOG3313 Molecular chaperone Prefoldin subunit 3
Length = 199
Score = 253 bits (646), Expect = 1e-67
Identities = 124/194 (63%), Positives = 157/194 (80%), Gaps = 7/194 (3%)
Query: 1 MDTLFNSAKTNPRGIPEAPFVEKVEQYVKSPEDFDMCFSKFQEHLSKYKYMQESKLANIK 60
MDTLFNS + N RGIP+APF+E V + +K P DF++CF+KFQE LSKYK+MQESKLA IK
Sbjct: 1 MDTLFNSTEKNARGIPQAPFIENVNEIIKDPSDFELCFNKFQERLSKYKFMQESKLATIK 60
Query: 61 QLKSKIPDIENTLNMCALLKQKRETXXXXXXXXXXXSLLINYQLNETLFSKASVN-PKD- 118
QLK++IPD+ENTL +C L+ + +L++YQLN+TL++KA V+ P+D
Sbjct: 61 QLKTRIPDLENTLKICQSLRNHSDEGDESDE-----PILLHYQLNDTLYTKAQVDIPEDR 115
Query: 119 PELKVGLWLGADVMLEYPLDEAIELLAQKLADAKQNLDISQQDVEFLRENITTMEVNCAR 178
+LKVGLWLGADVMLEYP+DEAIELL +KLAD++Q+L +S +DVEFLRENITTMEVNCAR
Sbjct: 116 ADLKVGLWLGADVMLEYPIDEAIELLKKKLADSEQSLTVSTEDVEFLRENITTMEVNCAR 175
Query: 179 LYNWDVQRRQQMKK 192
LYNWDVQRRQ +K+
Sbjct: 176 LYNWDVQRRQDLKQ 189
>Hs4507873 [O] KOG3313 Molecular chaperone Prefoldin subunit 3
Length = 197
Score = 139 bits (350), Expect = 2e-33
Identities = 77/178 (43%), Positives = 111/178 (62%), Gaps = 14/178 (7%)
Query: 14 GIPEAPFVEKVEQYVKSP--EDFDMCFSKFQEHLSKYKYMQESKLANIKQLKSKIPDIEN 71
GIPEA FVE V+ ++K P E D K E KYK+M+ + ++LK +IP+I+
Sbjct: 24 GIPEAVFVEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQ 83
Query: 72 TLNMCALLKQKRETXXXXXXXXXXXSLLINYQLNETLFSKASVNPKDPELKVGLWLGADV 131
TL + +++K+E+ S+ + L + L+ KASV P D KV LWLGA+V
Sbjct: 84 TLEILKYMQKKKESTN---------SMETRFLLADNLYCKASVPPTD---KVCLWLGANV 131
Query: 132 MLEYPLDEAIELLAQKLADAKQNLDISQQDVEFLRENITTMEVNCARLYNWDVQRRQQ 189
MLEY +DEA LL + L+ A +NLD ++D++FLR+ TT EVN AR+YNWDV+RR +
Sbjct: 132 MLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNK 189
>SPAC3H8.07c [O] KOG3313 Molecular chaperone Prefoldin subunit 3
Length = 169
Score = 135 bits (341), Expect = 3e-32
Identities = 80/184 (43%), Positives = 109/184 (58%), Gaps = 17/184 (9%)
Query: 8 AKTNPRGIPEAPFVEKVEQYVKSPEDFDMCFSKFQEHLSKYKYMQESKLANIKQLKSKIP 67
+ +NPRGIP A F E E S E+ KFQE ++KYK+M+ S + + L KIP
Sbjct: 2 SSSNPRGIPPAQFFEFKEL---SMEEAQGHLEKFQEAIAKYKFMETSVVRRVASLDDKIP 58
Query: 68 DIENTLNMCALLKQKRETXXXXXXXXXXXSLLINYQLNETLFSKASVNPKDPELKVGLWL 127
DI TL LK+++ S + Y+LN+TL +KA V KD V LWL
Sbjct: 59 DIRKTLQSVQFLKERQ-----------GDSFTVTYELNDTLNAKAEVEAKD---NVYLWL 104
Query: 128 GADVMLEYPLDEAIELLAQKLADAKQNLDISQQDVEFLRENITTMEVNCARLYNWDVQRR 187
GA+VMLEY ++EA LL QKL A++ L ++D+EFLR +TTMEVN AR+YN+ V R
Sbjct: 105 GANVMLEYTVEEAEALLTQKLNSAEETLKACKEDLEFLRAQVTTMEVNTARVYNYTVLLR 164
Query: 188 QQMK 191
++ K
Sbjct: 165 KKTK 168
>At5g49510 [O] KOG3313 Molecular chaperone Prefoldin subunit 3
Length = 195
Score = 123 bits (308), Expect = 2e-28
Identities = 70/180 (38%), Positives = 109/180 (59%), Gaps = 13/180 (7%)
Query: 10 TNPRGIPEAPFVEKVEQYV-KSPEDFDMCFSKFQEHLSKYKYMQESKLANIKQLKSKIPD 68
T RGIP A F++ VE Y+ +S D + + QE L +YK ++ LA + L++KIPD
Sbjct: 14 TERRGIPAAKFIQDVETYLSQSGLDPNSALAFHQERLQQYKVVEMKLLAQQRDLQAKIPD 73
Query: 69 IENTLNMCALLKQKRETXXXXXXXXXXXSLLINYQLNETLFSKASVNPKDPELKVGLWLG 128
IE L + A L+ K+ T +LL +++++E ++S+A + D V LWLG
Sbjct: 74 IEKCLEVVATLEAKKGTGE---------ALLADFEVSEGIYSRACIEDTD---SVCLWLG 121
Query: 129 ADVMLEYPLDEAIELLAQKLADAKQNLDISQQDVEFLRENITTMEVNCARLYNWDVQRRQ 188
A+VMLEY +EA LL L +AK +L++ D++FLR+ +T +V AR+YNWDV +R+
Sbjct: 122 ANVMLEYSCEEASALLKNNLENAKASLEVLVADLQFLRDQVTVTQVTIARVYNWDVHQRR 181
>7299441 [O] KOG3313 Molecular chaperone Prefoldin subunit 3
Length = 194
Score = 120 bits (301), Expect = 1e-27
Identities = 71/181 (39%), Positives = 103/181 (56%), Gaps = 17/181 (9%)
Query: 14 GIPEAPFVEKVEQYVKSPED--FDMCFSKFQEHLSKYKYMQESKLANIKQLKSKIPDIEN 71
GIPEA F+E+++ ++ PE+ + + E KY++M + A ++LKS+IPD+E
Sbjct: 22 GIPEAVFLEEIDTFMSQPENENCEKVLQRLDEQHGKYRFMACNLEARRRKLKSQIPDLER 81
Query: 72 TLNMCALLKQKRETXXXXXXXXXXXSLLINYQLNETLFSKASVNPKDPELKVGLWLGADV 131
+L M +L+++ E + L++ +F K V P V LWLGA V
Sbjct: 82 SLEMVNVLRKEDEERET------------QFLLSDQVFIKTLVPPTKT---VYLWLGASV 126
Query: 132 MLEYPLDEAIELLAQKLADAKQNLDISQQDVEFLRENITTMEVNCARLYNWDVQRRQQMK 191
MLEYPLDEA LL Q + A NL + D +FLR+ ITT EVN AR+YNW V++RQ
Sbjct: 127 MLEYPLDEAEALLNQNITSAVGNLKSVEHDQDFLRDQITTTEVNMARVYNWGVKKRQAAT 186
Query: 192 K 192
K
Sbjct: 187 K 187
>CE13349 [O] KOG3313 Molecular chaperone Prefoldin subunit 3
Length = 185
Score = 92.0 bits (227), Expect = 5e-19
Identities = 56/177 (31%), Positives = 99/177 (55%), Gaps = 13/177 (7%)
Query: 13 RGIPEAPFVEKVEQYV-KSPEDFDMCFSKFQEHLSKYKYMQESKLANIKQLKSKIPDIEN 71
RGIP++ +E VE ++ K + +E KYKY++ S LA ++ KIP+ EN
Sbjct: 11 RGIPKSELIEDVESWLTKEKLSIEEAEVVLREKYGKYKYVESSMLAQKVRMSEKIPEFEN 70
Query: 72 TLNMCALLKQKRETXXXXXXXXXXXSLLINYQLNETLFSKASVNPKDPELKVGLWLGADV 131
+L++ L KR S + L++ +++KA+V + PE KV +WLGA+V
Sbjct: 71 SLSIIDTLIAKR---------AADESFETTFLLSDDVYTKATV--QKPE-KVSIWLGANV 118
Query: 132 MLEYPLDEAIELLAQKLADAKQNLDISQQDVEFLRENITTMEVNCARLYNWDVQRRQ 188
M+EY L+ A +LL + ++ +D ++ ++++ ITT EVN + + N+ V +R+
Sbjct: 119 MVEYDLENARKLLDKNRGSVQKVVDELTNELSYIKDQITTTEVNMSHIVNFGVNKRR 175
>7291320 [O] KOG3313 Molecular chaperone Prefoldin subunit 3
Length = 163
Score = 50.4 bits (119), Expect = 2e-06
Identities = 44/174 (25%), Positives = 83/174 (47%), Gaps = 17/174 (9%)
Query: 15 IPEAPFVEKVEQYVKSPEDFDMCFSKFQEHLSKYKYMQESKLANIKQ--LKSKIPDIENT 72
IPEA V+ V Y+ PE + + + + + Y+Q S+LA + L + + +E
Sbjct: 3 IPEAKLVDDVVSYIAKPEFYSTVPAALK--MQRLFYVQYSELAAKLETDLTAVLTRLEAA 60
Query: 73 LNMCALLKQKRETXXXXXXXXXXXSLLINYQLNETLFSKASVNPKDPELKVGLWLGADVM 132
N L+++ + Q+ + +F S+ P KV L +GA +
Sbjct: 61 KNNLELVRRFIDNPDKEVHSLV--------QIAQGVFRWVSIPPVQ---KVTLQVGASLQ 109
Query: 133 LEYPLDEAIELLAQKLAD-AKQNLDISQQDVEFLRENITTMEVNCARLYNWDVQ 185
+E+ L EA E + + + KQ L + D+++L++ + T+E+N A LY +V+
Sbjct: 110 MEFELSEAEEFIKKDITSLVKQQLQ-HEHDIDYLQDQVNTIEMNLAVLYKHEVE 162
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.131 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,445,885
Number of Sequences: 60738
Number of extensions: 379597
Number of successful extensions: 1054
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1035
Number of HSP's gapped (non-prelim): 7
length of query: 197
length of database: 30,389,216
effective HSP length: 101
effective length of query: 96
effective length of database: 24,254,678
effective search space: 2328449088
effective search space used: 2328449088
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)