ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1233 suspect: HSP TZ KOG3671 Cytoskeleton Actin regulatory protein (Wiskott-Aldrich syndrome protein) r_klactIII1233 suspect: HSP TZ KOG3671 Signal transduction mechanisms Actin regulatory protein (Wiskott-Aldrich syndrome protein)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= r_klactIII1233 434720  436678 653  
         (653 letters)

Database: KOG eukaryal database 04/03 
           60,738 sequences; 30,389,216 total letters

Searching..................................................done

Color Key for Alignment Scores:   


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

YOR181w [TZ] KOG3671 Actin regulatory protein (Wiskott-Aldrich s...   277   4e-74
SPAC4F10.15c [TZ] KOG3671 Actin regulatory protein (Wiskott-Aldr...   125   2e-28
Hs4507909 [TZ] KOG3671 Actin regulatory protein (Wiskott-Aldrich...    61   6e-09
Hs4505323 [TZ] KOG3671 Actin regulatory protein (Wiskott-Aldrich...    58   4e-08

>YOR181w [TZ] KOG3671 Actin regulatory protein (Wiskott-Aldrich syndrome
           protein)
          Length = 633

 Score =  277 bits (708), Expect = 4e-74
 Identities = 131/194 (67%), Positives = 161/194 (82%)

Query: 1   MGGLNSAEKEKVKHALPKASNKIIDVTIARLYIAYPNPEKWVYTGLSGAIALVDDIVGNT 60
           MG LNS++KE +K ALPKASNKIIDVT+ARLYIAYP+  +W YTGLSGA+ALVDD+VGNT
Sbjct: 1   MGLLNSSDKEIIKRALPKASNKIIDVTVARLYIAYPDKNEWQYTGLSGALALVDDLVGNT 60

Query: 61  FFLKLIDVHGHRGVLWDQELYVNFQYNQDRTFFHTFELEQCNAGLLFTDIGDASHFLKRV 120
           FFLKL+D++GHRGV+WDQELYVNF+Y QDRTFFHTFE+E+C AGLLF DI +ASHFLKRV
Sbjct: 61  FFLKLVDINGHRGVIWDQELYVNFEYYQDRTFFHTFEMEECFAGLLFVDINEASHFLKRV 120

Query: 121 QKREKYASKKTLANKNAIALEDQIKKEEESKVIHGPRGESLISDQRVRYRYEPEKHEHRQ 180
           QKRE+YA++KTL NKNA+AL  ++++E++S+V+HGPRGESLI +QR RY YE        
Sbjct: 121 QKRERYANRKTLLNKNAVALTKKVREEQKSQVVHGPRGESLIDNQRKRYNYEDVDTIPTT 180

Query: 181 EHHYEQPSQNYAST 194
           +H    P    A T
Sbjct: 181 KHKAPPPPPPTAET 194



 Score =  103 bits (258), Expect = 6e-22
 Identities = 54/98 (55%), Positives = 62/98 (63%), Gaps = 1/98 (1%)

Query: 557 GSGFVENTGDAGRDALLASIRGAG-LNSLRKVDKSQLEKPSPLLQEVRSDAPVSQPTGGS 615
           G  F E TGDAGRDALLASIRGAG + +LRKVDKSQL+KPS LLQE R ++       G+
Sbjct: 536 GGSFAETTGDAGRDALLASIRGAGGIGALRKVDKSQLDKPSVLLQEARGESASPPAAAGN 595

Query: 616 TGGPVGXXXXXXXXXXXXXNQRKNKVARDDDIDNGDDW 653
            G P G             N+RK KV   DD+DNGDDW
Sbjct: 596 GGTPGGPPASLADALAAALNKRKTKVGAHDDMDNGDDW 633


>SPAC4F10.15c [TZ] KOG3671 Actin regulatory protein (Wiskott-Aldrich syndrome
           protein)
          Length = 574

 Score =  125 bits (314), Expect = 2e-28
 Identities = 55/117 (47%), Positives = 77/117 (65%)

Query: 4   LNSAEKEKVKHALPKASNKIIDVTIARLYIAYPNPEKWVYTGLSGAIALVDDIVGNTFFL 63
           +   +K  ++  +PK++NKII   + +LY+AYP+P KW YTGL GA+ L  D      + 
Sbjct: 7   ITQEDKATIRKYIPKSTNKIIAAAVVKLYVAYPDPNKWNYTGLCGALVLSYDTTAKCCWF 66

Query: 64  KLIDVHGHRGVLWDQELYVNFQYNQDRTFFHTFELEQCNAGLLFTDIGDASHFLKRV 120
           KL+DV  + G++WDQELY N  Y QDRTFFH+FEL++C AG  F +  DA  F K+V
Sbjct: 67  KLVDVVNNSGIIWDQELYQNMDYRQDRTFFHSFELDKCLAGFSFANETDAQKFYKKV 123


>Hs4507909 [TZ] KOG3671 Actin regulatory protein (Wiskott-Aldrich syndrome
           protein)
          Length = 502

 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 3/97 (3%)

Query: 28  IARLYIAYP-NPEKWVYTGLSGAIALVDDIVGNTFFLKLIDVHGHRGVLWDQELYVNFQY 86
           + +LY+A P   E W      GA+  V D    ++F++L  +   R +LW+QELY    Y
Sbjct: 50  VVQLYLALPPGAEHWTKEHC-GAVCFVKDNPQKSYFIRLYGLQAGR-LLWEQELYSQLVY 107

Query: 87  NQDRTFFHTFELEQCNAGLLFTDIGDASHFLKRVQKR 123
           +    FFHTF  + C AGL F D  +A  F   VQ++
Sbjct: 108 STPTPFFHTFAGDDCQAGLNFADEDEAQAFRALVQEK 144


>Hs4505323 [TZ] KOG3671 Actin regulatory protein (Wiskott-Aldrich syndrome
           protein)
          Length = 505

 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 32/88 (36%), Positives = 48/88 (54%), Gaps = 5/88 (5%)

Query: 47  SGAIALVDDIVGNTFFLKLIDVHGHRGVLWDQELYVNFQYNQDRTFFHTFELEQCNAGLL 106
           SG   LV D    + FL++ D+   + +LW+QELY NF YN  R +FHTF  + C   L 
Sbjct: 62  SGVACLVKDNPQRSHFLRIFDIKDGK-LLWEQELYNNFVYNSPRGYFHTFAGDTCQVALN 120

Query: 107 FTDIGDASHFLKRVQ----KREKYASKK 130
           F +  +A  F K V     +R++ + K+
Sbjct: 121 FANEEEAKKFRKAVTDLLGRRQRKSEKR 148


  Database: KOG eukaryal database 04/03
    Posted date:  Apr 14, 2003  1:07 PM
  Number of letters in database: 30,389,216
  Number of sequences in database:  60,738
  
Lambda     K      H
   0.313    0.132    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,473,012
Number of Sequences: 60738
Number of extensions: 1008802
Number of successful extensions: 2236
Number of sequences better than 1.0e-05: 4
Number of HSP's better than  0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 2231
Number of HSP's gapped (non-prelim): 6
length of query: 653
length of database: 30,389,216
effective HSP length: 113
effective length of query: 540
effective length of database: 23,525,822
effective search space: 12703943880
effective search space used: 12703943880
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)