ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1308 good J KOG1465 Translation, ribosomal structure and biogenesis Translation initiation factor 2B, beta subunit (eIF-2Bbeta/GCD7)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1308 462445 461378 -356
(356 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR291c [J] KOG1465 Translation initiation factor 2B beta subuni... 496 e-140
SPAC343.14c [J] KOG1465 Translation initiation factor 2B beta su... 255 8e-68
Hs7657058 [J] KOG1465 Translation initiation factor 2B beta subu... 190 3e-48
7290350 [J] KOG1465 Translation initiation factor 2B beta subuni... 164 2e-40
At3g07300 [J] KOG1465 Translation initiation factor 2B beta subu... 152 6e-37
7301868 [J] KOG1466 Translation initiation factor 2B alpha subun... 82 2e-15
At1g72340 [J] KOG1466 Translation initiation factor 2B alpha sub... 77 5e-14
CE20267 [J] KOG1465 Translation initiation factor 2B beta subuni... 71 3e-12
Hs4503503 [J] KOG1466 Translation initiation factor 2B alpha sub... 65 1e-10
At2g44070 [J] KOG1467 Translation initiation factor 2B delta sub... 64 3e-10
SPCC11E10.07c [J] KOG1466 Translation initiation factor 2B alpha... 62 2e-09
YKR026c [J] KOG1466 Translation initiation factor 2B alpha subun... 61 2e-09
CE00367 [J] KOG1466 Translation initiation factor 2B alpha subun... 61 3e-09
At1g53900_2 [J] KOG1466 Translation initiation factor 2B alpha s... 60 5e-09
At1g53880_2 [J] KOG1466 Translation initiation factor 2B alpha s... 60 5e-09
At5g38640 [J] KOG1467 Translation initiation factor 2B delta sub... 58 2e-08
SPAC21E11.06 [J] KOG1467 Translation initiation factor 2B delta ... 58 2e-08
At1g48970 [J] KOG1467 Translation initiation factor 2B delta sub... 56 7e-08
>YLR291c [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 381
Score = 496 bits (1278), Expect = e-140
Identities = 249/365 (68%), Positives = 294/365 (80%), Gaps = 18/365 (4%)
Query: 2 SDINVVIDSFIDRLKRKQVIGSYQASLETLQILMRYVSAIRWTSTDELIVQIKKFGNNLE 61
SD+NV ID+F+ +LKR+QV GSY +LETLQ+LMR++SA RW ++LI QI+ GN+LE
Sbjct: 16 SDVNVTIDTFVAKLKRRQVQGSYAIALETLQLLMRFISAARWNHVNDLIEQIRDLGNSLE 75
Query: 62 KAQPYEYSCGNVVRRVLSMIRDEIEEEQSS--------AEPMISSMFNLLQKPMTDTKTR 113
KA P +SCGNV+RR+L+++RDE+EE+ S AEP+ISSMFNLLQKP + R
Sbjct: 76 KAHPTAFSCGNVIRRILAVLRDEVEEDTMSTTVTSTSVAEPLISSMFNLLQKPEQPHQNR 135
Query: 114 KIQDN------KLDVRQTIVQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKT 167
K K D RQ +Q I+DLIDEIKNIDEGIQQIAI+LIHD EILLTPTPDSKT
Sbjct: 136 KNSSGSSSMKTKTDYRQVAIQGIKDLIDEIKNIDEGIQQIAIDLIHDHEILLTPTPDSKT 195
Query: 168 VLRFLLKARERNNRNFTVLVTEGFPNNTTVAHEFAKKLSEHDIETIVIPDSAVFALMSRV 227
VL+FL+ ARER+NR FTVLVTEGFPNNT AHEFAKKL++H+IET+V+PDSAVFALMSRV
Sbjct: 196 VLKFLITARERSNRTFTVLVTEGFPNNTKNAHEFAKKLAQHNIETLVVPDSAVFALMSRV 255
Query: 228 GKVIIGAKTVFTNGGTISSTAGVSSVCECAREFKTPVFAVAGLYKLSPLYPFDVEKMVEI 287
GKVIIG K VF NGGTISS +GVSSVCECAREF+TPVFAVAGLYKLSPLYPFDVEK VE
Sbjct: 256 GKVIIGTKAVFVNGGTISSNSGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKFVEF 315
Query: 288 GGSQNVLPTTENDRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFIYRVVWDNYKQ 347
GGSQ +LP + + L+T+N I DY+PPENIDIYITN+GGF PSFIYR+ WDNYKQ
Sbjct: 316 GGSQRILPRMDPRK----RLDTVNQITDYVPPENIDIYITNVGGFNPSFIYRIAWDNYKQ 371
Query: 348 EDVNL 352
DV+L
Sbjct: 372 IDVHL 376
>SPAC343.14c [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 393
Score = 255 bits (651), Expect = 8e-68
Identities = 144/399 (36%), Positives = 230/399 (57%), Gaps = 53/399 (13%)
Query: 1 MSDINV-----VIDSFIDRLKRKQVIGSYQASLETLQILMRYVSAIRWTSTDELIVQIKK 55
MS INV + S I LK ++V G + ++ET ++ + +S RW++ D+LI ++
Sbjct: 1 MSTINVEHTYPAVSSLIADLKSRKVQGPFAVAVETALVMRQVISQTRWSTVDQLIDTVRA 60
Query: 56 FGNNLEKAQPYEYSCGNVVRRVLSMIRDEIEE--------------EQSSAEP------- 94
G+ L KAQP E+SCGN++RR+L +IR+E +E +S+ P
Sbjct: 61 VGSTLVKAQPTEFSCGNIIRRILRLIREEYQELLKTADENEKLIVSSSNSSSPSQKRDIP 120
Query: 95 ---------------MISSMFNLLQKPMTDTKT--RKIQDNK----LDVRQTIVQSIRDL 133
M SSM NLL +P ++ T + + D++ +D+R I+ I+D+
Sbjct: 121 SNEKLVQSHEPVSVQMYSSMLNLLGRPTLESPTHSKTVGDSRVTGGMDMRAVIISGIQDV 180
Query: 134 IDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKARERNNRNFTVLVTEGFPN 193
IDE+ I+ I+ +++ +H EI+LT SKTV FL A ++ R F+V+V EGFPN
Sbjct: 181 IDELDKINTDIEVQSMDHLHSNEIILTQGC-SKTVEAFLRFAAKK--RKFSVIVAEGFPN 237
Query: 194 NTTVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFTNGGTISSTAGVSSV 253
N +H AK+L++ I+T VI D+ +FA+MSRV KVI+G + NGG + + +G V
Sbjct: 238 NQKGSHAMAKRLAQAGIDTTVISDATIFAIMSRVNKVILGTHAILGNGGLV-TYSGAQLV 296
Query: 254 CECAREFKTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPTTENDRVGTVALETINPI 313
+ AR TPV +G+YKLSP+YP+D+E ++++ ++ E D + E +NP
Sbjct: 297 AQAARHHATPVVVCSGIYKLSPVYPYDLESIIQLSSPDKIMSFNEGDLISRA--EILNPY 354
Query: 314 ADYIPPENIDIYITNIGGFAPSFIYRVVWDNYKQEDVNL 352
DYIPP+ +D++ITN+GG+ PS++YR++ D Y D L
Sbjct: 355 YDYIPPDLVDLFITNLGGYPPSYLYRIMNDTYDASDTIL 393
>Hs7657058 [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 351
Score = 190 bits (482), Expect = 3e-48
Identities = 123/350 (35%), Positives = 199/350 (56%), Gaps = 12/350 (3%)
Query: 2 SDINVVIDSFIDRLKRKQ-VIGSYQASLETLQILMRYVSAIRWTSTDELIVQIKKFGNNL 60
S+++ I+SF++ LKR S + + ETL +L + ++ RW++ EL+ I++ G +
Sbjct: 9 SELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRREGRRM 68
Query: 61 EKAQPYEYSCGNVVRRVLSMIRDEIEEEQSSAEPMISSMFNLLQKPMTDTKTRK-IQDNK 119
AQP E + GN+VRRVL +IR+E ++ S L K +T + +
Sbjct: 69 TAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDE--SDQQESLHKLLTSGGLNEDFSFHY 126
Query: 120 LDVRQTIVQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKARERN 179
++ I+++I +L+ E++ E I A+E IH E+++T S+TV FL +A +
Sbjct: 127 AQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMT-IGFSRTVEAFLKEAARK- 184
Query: 180 NRNFTVLVTEGFPNNTTVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFT 239
R F V+V E P HE A LS+ IET V+ D+A+FA+MSRV KVIIG KT+
Sbjct: 185 -RKFHVIVAECAP--FCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILA 241
Query: 240 NGGTISSTAGVSSVCECAREFKTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPTTEN 299
N G + + G ++ A+ TP+ A ++KLSP +P + + + + VLP TE
Sbjct: 242 N-GALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEG 300
Query: 300 DRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFIYRVVWDNYKQED 349
D + V++ P+ DY+PPE I ++I+NIGG APS+IYR++ + Y +D
Sbjct: 301 DILEKVSVHC--PVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDD 348
>7290350 [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 352
Score = 164 bits (414), Expect = 2e-40
Identities = 110/354 (31%), Positives = 191/354 (53%), Gaps = 19/354 (5%)
Query: 8 IDSFIDRLKRKQVIGSYQASLETLQILMRYVSAIRWTSTDELIVQIKKFGNNLEKAQPYE 67
I I +K V GSY + +TL I + + W + D L+ ++ L+ A P E
Sbjct: 9 ITQLIHAIKVGLVEGSYNITNKTLDIFKYIIMSKSWQNADALMQIVRDQCKILQAALPQE 68
Query: 68 YSCGNVVRRVLSMIRDEIE----EEQSSAEPMISSMFNLLQKPMTDTKTRKIQDN----K 119
N+ RR+L + R+E + + Q A+ +S+ L K +T T + + +
Sbjct: 69 TVTSNIARRILKLTREEFDLLHAKVQHFADDSQASLS--LHKLVTQTSESNVSVDYSVPQ 126
Query: 120 LDVRQTIVQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKARERN 179
+R+ ++ ++++ E++ E I A E IH EI+LT S++V FL +A ++
Sbjct: 127 HGLREALLDHLQEVETELETSSENICVQAEEHIHSSEIILT-LGHSRSVENFLKRAIKKR 185
Query: 180 NRNFTVLVTEGFPNNTTVAHEFAKKLS-EHDIETIVIPDSAVFALMSRVGKVIIGAKTVF 238
+ T++V E P H A L+ E ++E +VIPD+A+FA+MSRV KVIIG +V
Sbjct: 186 -QFLTIIVAECAP--ACRGHNLAASLANEKNVEIVVIPDAAIFAMMSRVNKVIIGTHSVL 242
Query: 239 TNGGTISSTAGVSSVCECAREFKTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPTTE 298
NGG + + G +V A+ + PV +A +YKLSPL+ + + +G +++V+P
Sbjct: 243 ANGG-LRAACGAYTVALAAKHYSVPVIVLAPMYKLSPLHLCEQDAFNMVGCAEDVIP--- 298
Query: 299 NDRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFIYRVVWDNYKQEDVNL 352
D + + +P+ DY+PPE + ++I+N GG APS++YR++ + Y ED+ +
Sbjct: 299 YDSIPAREAKVYSPMFDYVPPELVTLFISNTGGHAPSYVYRLLTELYHPEDLEI 352
>At3g07300 [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 384
Score = 152 bits (385), Expect = 6e-37
Identities = 118/388 (30%), Positives = 182/388 (46%), Gaps = 65/388 (16%)
Query: 1 MSDINVVIDSFIDRLKRKQVIGSYQASLETLQILMRYVSAIRWTSTDE---LIVQIKKFG 57
M D+ + F+++L+++++ GS + T+++L +S R ++ LI +K G
Sbjct: 1 MPDVQSTVVEFVNKLRKRKIEGSQATAKYTVELLRSVISHQRVPHANQAAALIDAVKAVG 60
Query: 58 NNLEKAQPYEYSCGNVVRRVLSMIRDE----------------------------IEEEQ 89
L A P E + GNVVRRVL +IR+E I
Sbjct: 61 EQLIAANPVELAVGNVVRRVLHIIREEDLSLTTAAMGGLDLLDASDDDDVDNCKGIGFPA 120
Query: 90 SSAEPMISSMFNLLQKPMTDT-----------------------KTRKIQDNKLDVRQTI 126
SA + ++ + L+ P T KT ++ +
Sbjct: 121 MSAAVVAAAARSTLRPPSLQTLLEGTPESATVPYTSSSGADSESKTADKSSLTRKLKHDV 180
Query: 127 VQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKARERNNRNFTVL 186
++ + LI EI E I + AIE IH E++LT S+TVL FL A+E+ R+F V
Sbjct: 181 IEGVNQLIQEIAGCHEQIAEQAIEHIHQNEVILT-LGSSRTVLEFLCAAKEKK-RSFRVF 238
Query: 187 VTEGFPNNTTVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFTNGGTISS 246
V EG P H AK+L ++T VI DSAVFA++SRV VIIGA V NGG I
Sbjct: 239 VAEGAPRYQ--GHLLAKELVARGLQTTVITDSAVFAMISRVNMVIIGAHAVMANGGVI-G 295
Query: 247 TAGVSSVCECAREFKTPVFAVAGLYKLSPLYPFDVEKMV-EIGGSQNVLPTTE-----ND 300
GV+ A++ P +AG +KL PLYP + E ++ E+ +L E +
Sbjct: 296 PVGVNMAALAAQKHAVPFVVLAGSHKLCPLYPHNPEVLLNELRSPSELLDFGEFSDCLDF 355
Query: 301 RVGTVALETINPIADYIPPENIDIYITN 328
G+ +L+ +NP DY+PP + ++IT+
Sbjct: 356 GAGSGSLQVVNPTFDYVPPNLVSLFITD 383
>7301868 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 306
Score = 81.6 bits (200), Expect = 2e-15
Identities = 66/218 (30%), Positives = 107/218 (48%), Gaps = 16/218 (7%)
Query: 121 DVRQTIVQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKARERNN 180
+ RQ ++ + + ++ N + I Q A I D +LT + S+ VL+ L+ A + N
Sbjct: 95 ECRQIMLNRGKIFLTKLLNSRQVIAQQAQRFITDGCRILTHSR-SRVVLKALITASQ-NK 152
Query: 181 RNFTVLVTEGFPNNTTVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFTN 240
++F V VT+G N+ E K L I+ +I DSA +M V V++GA+ V +
Sbjct: 153 KSFHVYVTQGGTGNS--GEEMVKDLHAAGIDCTLILDSATGYVMESVDFVLVGAEAVVES 210
Query: 241 GGTISSTAGVSSVCECAREFKTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPTT-EN 299
GG I+ G ++ CARE K P + +A +K S LYP +Q LP +
Sbjct: 211 GGIINRI-GTYTMGLCAREMKKPFYVLAESFKFSRLYPL----------NQRDLPNEYKY 259
Query: 300 DRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFI 337
R + ++P+ DY PP I + T++G PS +
Sbjct: 260 SRKHLNDVSKVHPLVDYTPPVYITLLFTDLGRLTPSAV 297
>At1g72340 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 362
Score = 76.6 bits (187), Expect = 5e-14
Identities = 56/173 (32%), Positives = 85/173 (48%), Gaps = 10/173 (5%)
Query: 165 SKTVLRFLLKARERNNRNFTVLVTEGFPNNTTVAHEFAKKLSEHDIETIVIPDSAVFALM 224
S+ VL +LK +NN+ F VL TEG P+ T V + +LS+ DI ++ DSAV M
Sbjct: 191 SRVVLE-ILKTAAQNNKLFRVLCTEGRPDGTGVL--LSSELSKLDIPVKLLLDSAVAYSM 247
Query: 225 SRVGKVIIGAKTVFTNGGTISSTAGVSSVCECAREFKTPVFAVAGLYKLSPLYPFDVEKM 284
V V +GA V +GG I + G + A PV+ A YK + LYP D + M
Sbjct: 248 DEVDMVFVGADGVVESGGII-NMMGTYQIALVAHSMNKPVYVAAESYKFARLYPLDQKDM 306
Query: 285 VEIGGSQNVLPTTENDRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFI 337
+ + P ++ T +E DY PP+ + + T++G +PS +
Sbjct: 307 -----APALRPIEFGVKIPT-KVEVERSARDYTPPQYLTLLFTDLGVLSPSVV 353
>CE20267 [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 340
Score = 70.9 bits (172), Expect = 3e-12
Identities = 70/354 (19%), Positives = 154/354 (42%), Gaps = 21/354 (5%)
Query: 1 MSDINVVID---SFIDRLKRKQVIGSYQA-SLETLQILMRYVSAIRWTSTDELIVQIKKF 56
MS N + D +FI L++K S + ++ T+ ++ + + + ++L V +
Sbjct: 1 MSSDNEIEDLKRAFIFALRKKFPRDSSSSIAIATVNLIRKIIFRENPKTMNDLQVSLANH 60
Query: 57 GNNLEKAQPYEYSCGNVVRRVLSMIRDEIEEEQSSAEPMISSMFNLLQKPMTDTKTRKIQ 116
L A+ E N+ + + RDE+ +++ EP ++ L + K K
Sbjct: 61 CKKLHGAERSELIIINIGLMITKLARDEVLQKKGGGEP--EPLYTLWRDDDETIKKLKTA 118
Query: 117 DNKLDVRQTIVQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKAR 176
D K +++ + SI++L+ EI++ E I + EL+ + +++L + S + L
Sbjct: 119 DMK-KIKKDLQASIKELVTEIESSRECIASQSTELLFNNDVVLVHSLRSSQTMHNFLSHA 177
Query: 177 ERNNRNFTVLVTEGFPNNTTVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKT 236
++ R V+ + +FA + +++ + M KV++ A
Sbjct: 178 VKSGRKHRVIDVVDEEEHIESTPDFATAIELYEVAS----------KMPEASKVVLVAAA 227
Query: 237 VFTNGGTISSTAGVSSVCECAREFKTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPT 296
F +G + AG + A+ PV+ +A YKL P + + + + N LP
Sbjct: 228 YFPDGSCLVP-AGGHQIALLAKRHCVPVYVLAPFYKLCPFFMTNPDSLHTF--RSNSLPF 284
Query: 297 TENDRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFIYRVVWDNYKQEDV 350
+ + + ++ ++P D + + + ++++N PS + R+ D Y +D+
Sbjct: 285 DLSAKSAGL-VDCLHPAFDCLQSDLVTLFVSNTSCVIPSHVNRLKEDYYHSQDI 337
>Hs4503503 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 305
Score = 65.5 bits (158), Expect = 1e-10
Identities = 52/176 (29%), Positives = 83/176 (46%), Gaps = 13/176 (7%)
Query: 165 SKTVLRFLLKARERNNRNFTVLVTEGFPNNTTVAHEFAKKLSEHDIETIVIPDSAVFALM 224
S+ VLR +L+A + F+V VTE P+ + + AK L ++ V+ D+AV +M
Sbjct: 131 SRVVLR-VLEAAVAAKKRFSVYVTESQPDLS--GKKMAKALCHLNVPVTVVLDAAVGYIM 187
Query: 225 SRVGKVIIGAKTVFTNGGTISSTAGVSSVCECAREFKTPVFAVAGLYKLSPLYPF---DV 281
+ VI+GA+ V NGG I+ G + + CA+ P + VA +K L+P DV
Sbjct: 188 EKADLVIVGAEGVVENGGIINK-IGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDV 246
Query: 282 EKMVEIGGSQNVLPTTENDRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFI 337
+ + T D L+ +P DY P I + T++G PS +
Sbjct: 247 PDKFKYKADTLKVAQTGQD------LKEEHPWVDYTAPSLITLLFTDLGVLTPSAV 296
>At2g44070 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 307
Score = 64.3 bits (155), Expect = 3e-10
Identities = 74/333 (22%), Positives = 129/333 (38%), Gaps = 42/333 (12%)
Query: 32 QILMRYVSAIRWTSTDELIVQIKKFGNNLEKAQPYEYSCGNVVRRVLSMIRDEIEEEQSS 91
+++ Y + T ++ QI + + L + +P S GN +R V + I
Sbjct: 7 EVVKDYSTPPENTLNRDMTAQISSYVSFLIECRPLSISMGNAIRFVKNRIA--------- 57
Query: 92 AEPMISSMFNLLQKPMTDTKTRKIQDNKLDVRQTIVQSIRDLIDEIKNIDEGIQQIAIEL 151
+ P+T +++ D+ R + ++I D I + A+
Sbjct: 58 ------------KLPITLSESEAKASLHSDIE-------RFINEKIIGADTVIVEHAVTK 98
Query: 152 IHDREILLTPTPDSKTVLRFLLKARERNNRNFTVLVTEGFPNNTTVAHEFAKKLSEHDIE 211
I D ++LLT S TV+ +L + F V V + P ++L + I
Sbjct: 99 IRDGDVLLTY--GSSTVIEMILVHAHELGKKFRVFVVDSRPK--LQGKLLLRRLIKRGIN 154
Query: 212 TIVIPDSAVFALMSRVGKVIIGAKTVFTNGGTISSTAGVSSVCECAREFKTPVFAVAGLY 271
+A+ +M +V KV +GA +VF+N GT+ S G + V A F+ PV Y
Sbjct: 155 CTYTHITAISYIMHQVTKVFLGASSVFSN-GTVYSRVGTACVAMVANAFRVPVLVCCEAY 213
Query: 272 KLSPLYPFDVEKMVEIGGSQNVLPTTE--------NDRVGTVALETINPIADYIPPENID 323
K D G N + N L+ +N + D P + I
Sbjct: 214 KFHEKVQLDYSICSNELGDPNAISKVHGREDINYLNGLTNNAKLKFLNLMYDATPSDYIS 273
Query: 324 IYITNIGGFAPSFIYRVVWDNYKQEDVNLGEKI 356
+ IT+ G P+ + V+ Y++E + KI
Sbjct: 274 MIITDYGMVPPTSV-PVIVREYQKEHLLQSSKI 305
>SPCC11E10.07c [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 341
Score = 61.6 bits (148), Expect = 2e-09
Identities = 61/226 (26%), Positives = 98/226 (42%), Gaps = 23/226 (10%)
Query: 123 RQTIVQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKARERNNRN 182
++ +V++ + I + + I + LI D ++LT S+ V LL A +R+ R
Sbjct: 104 KRHLVENGKLFIQRARACRQRIAHLGYPLIRDGSVILTHG-FSRGVAAVLLAAAKRHVR- 161
Query: 183 FTVLVTEGFPNNTTVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFTNGG 242
F V VTE P+ + + L I T ++ DSAV M+RV V++GA+ V NGG
Sbjct: 162 FKVFVTESRPSGSGCL--MTRTLKNACIPTCMVLDSAVSFTMNRVDLVLVGAEGVVENGG 219
Query: 243 TISSTAGVSSVCECAREFKTPVFAVAGLYKLSPLYP--------------FDVEKMVEIG 288
I+ G + A+ P +AVA +K ++P FD +
Sbjct: 220 LINQ-IGTFQLAVFAKHAHKPFYAVAESHKFVRMFPLSQYDIPFSRPILEFDDPSPETVH 278
Query: 289 GSQNVLPT----TENDRVGTVALETINPIADYIPPENIDIYITNIG 330
+PT N+ + NP D PPE + IT++G
Sbjct: 279 PEPEPIPTPSDAIHNELIMNEEQIRNNPTLDVTPPEFVSGLITDLG 324
>YKR026c [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 305
Score = 61.2 bits (147), Expect = 2e-09
Identities = 56/215 (26%), Positives = 94/215 (43%), Gaps = 10/215 (4%)
Query: 123 RQTIVQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKARERNNRN 182
+Q ++++ + + K I +I ++ I D +I+L S+ V L A + R
Sbjct: 91 KQHLIENGQLFVSRAKKSRNKIAEIGVDFIADDDIILVHGY-SRAVFSLLNHAANKFIR- 148
Query: 183 FTVLVTEGFPNNTTVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFTNGG 242
F +VTE P+ ++ L + I +I DSAV A++ +V KV +GA+ V +GG
Sbjct: 149 FRCVVTESRPSKQ--GNQLYTLLEQKGIPVTLIVDSAVGAVIDKVDKVFVGAEGVAESGG 206
Query: 243 TISSTAGVSSVCECAREFKTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPTTENDRV 302
I + G SV A + P + V +K ++P + + G P R
Sbjct: 207 II-NLVGTYSVGVLAHNARKPFYVVTESHKFVRMFPLSSDDLPMAGP-----PLDFTRRT 260
Query: 303 GTVALETINPIADYIPPENIDIYITNIGGFAPSFI 337
+ P DY E I IT++G PS +
Sbjct: 261 DDLEDALRGPTIDYTAQEYITALITDLGVLTPSAV 295
>CE00367 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 305
Score = 60.8 bits (146), Expect = 3e-09
Identities = 77/334 (23%), Positives = 134/334 (40%), Gaps = 46/334 (13%)
Query: 7 VIDSFIDRLKRKQVIGSYQASLETLQILMRYVSAIRWTSTDELIVQIKKFGNNLEKAQPY 66
+I SF +L+ S SL T++ L+ + R T+ E ++ + LEK
Sbjct: 6 IISSFRGKLENDP---SKSTSLATVETLLEVLDRSRATTVAEFQNELNQVVAALEKT--- 59
Query: 67 EYSCGNVVRRVLSMIRDEIEEEQSSAEPMISSMFNLLQKPMTDTKTRKIQDNKLDVRQTI 126
+YS ++ SA + + +L + D Q++ V
Sbjct: 60 DYSSTSI----------------RSAADLFTRFTSLAPAALLD------QEDFSQVLDLY 97
Query: 127 VQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKARERNNRNFTVL 186
Q R I ++ I + A L + + SK VL +L A ++ + V
Sbjct: 98 RQRARSFIKNVRGSRAKISKCA-RLFFTHHMNILTHSYSKVVLETILDAH-KSGYHLHVW 155
Query: 187 VTEGFPNNTTVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFTNGGTISS 246
VTE P+ + ++L ++ + T ++ DS V +M R+ V++GA+ V GG I+
Sbjct: 156 VTESQPDAS--GKLVFEELKKNGVPTTLVLDSCVGYVMERIQAVLVGAEGVMETGGIINK 213
Query: 247 TAGVSSVCECAREFKTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPTTENDRVGTVA 306
G +VC A+ PV+ A K +P +Q +P R +
Sbjct: 214 -IGTVNVCIIAKSRHVPVYVCAETIKFVREFPL----------NQADIPQEFKYRTSVIE 262
Query: 307 ---LETINPIADYIPPENIDIYITNIGGFAPSFI 337
LE +P DY PE + + IT++G P +
Sbjct: 263 RNNLELEHPDVDYTAPEFLTLIITDVGAMKPEAV 296
>At1g53900_2 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 402
Score = 60.1 bits (144), Expect = 5e-09
Identities = 51/170 (30%), Positives = 74/170 (43%), Gaps = 24/170 (14%)
Query: 172 LLKARERNNRNFTVLVTEGFPNNTTVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVI 231
+LK +N + F VL T +A+E AK DI ++ DSAV M V V
Sbjct: 244 ILKTSAQNKKLFRVLCT-----GVLLANELAKL----DIPVKLLIDSAVAYSMDEVDMVF 294
Query: 232 IGAKTVFTNGGTISSTAGVSSVCECAREFKTPVFAVAGLYKLSPLYPFDVEKMV----EI 287
+GA V +GG I + G + A+ PV+ A YK + LYP D + + I
Sbjct: 295 VGADGVVESGGII-NMMGTYQIALVAQSMNKPVYVAAESYKFARLYPLDQKDLEPALRPI 353
Query: 288 GGSQNVLPTTENDRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFI 337
S V P E +R DY PP+ + + T++G PS +
Sbjct: 354 DFSVPVPPKVEVER----------SARDYTPPQYLTLLFTDLGVLTPSVV 393
>At1g53880_2 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 402
Score = 60.1 bits (144), Expect = 5e-09
Identities = 51/170 (30%), Positives = 74/170 (43%), Gaps = 24/170 (14%)
Query: 172 LLKARERNNRNFTVLVTEGFPNNTTVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVI 231
+LK +N + F VL T +A+E AK DI ++ DSAV M V V
Sbjct: 244 ILKTSAQNKKLFRVLCT-----GVLLANELAKL----DIPVKLLIDSAVAYSMDEVDMVF 294
Query: 232 IGAKTVFTNGGTISSTAGVSSVCECAREFKTPVFAVAGLYKLSPLYPFDVEKMV----EI 287
+GA V +GG I + G + A+ PV+ A YK + LYP D + + I
Sbjct: 295 VGADGVVESGGII-NMMGTYQIALVAQSMNKPVYVAAESYKFARLYPLDQKDLEPALRPI 353
Query: 288 GGSQNVLPTTENDRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFI 337
S V P E +R DY PP+ + + T++G PS +
Sbjct: 354 DFSVPVPPKVEVER----------SARDYTPPQYLTLLFTDLGVLTPSVV 393
>At5g38640 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 642
Score = 58.2 bits (139), Expect = 2e-08
Identities = 61/262 (23%), Positives = 106/262 (40%), Gaps = 13/262 (4%)
Query: 94 PMISSMFNLLQKPMTDTKTRKIQDNKLDVRQTIVQSIRDLIDE-IKNIDEGIQQIAIELI 152
P+ SM N ++ I ++ + + T+ I I+E I D I + A+ I
Sbjct: 382 PLSISMGNAIRFVKNRIAKLPITLSESEAKATLQSDIERFINEKIIVADTVIVKHAVTKI 441
Query: 153 HDREILLTPTPDSKTVLRFLLKARERNNRNFTVLVTEGFPNNTTVAHEFAKKLSEHDIET 212
D ++LLT S T + ++ + F VLV + P ++L + I
Sbjct: 442 RDGDVLLTY--GSPTAVEMVILHAHELRKKFRVLVVDSRPK--LEGQLLLRRLIKRGINC 497
Query: 213 IVIPDSAVFALMSRVGKVIIGAKTVFTNGGTISSTAGVSSVCECAREFKTPVFAVAGLYK 272
+A+ +M V KV +GA +V +NG T+ S G + V A F+ PV YK
Sbjct: 498 TYTHINAISYIMHEVTKVFLGASSVLSNG-TVYSRVGTACVAMVANAFRVPVLVCCEAYK 556
Query: 273 LSPLYPFDVEKMVEIGGSQNVLPTTENDRV-------GTVALETINPIADYIPPENIDIY 325
D E+G + + + L+ +N + D P + I +
Sbjct: 557 FHERVQLDSICSNELGDPNAISEVHGREDINYLDGLTNNANLQFLNLMYDATPSDYISMI 616
Query: 326 ITNIGGFAPSFIYRVVWDNYKQ 347
IT+ G P+ + +V + K+
Sbjct: 617 ITDYGMVPPTSVPVIVREYQKE 638
>SPAC21E11.06 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 467
Score = 57.8 bits (138), Expect = 2e-08
Identities = 80/348 (22%), Positives = 136/348 (38%), Gaps = 48/348 (13%)
Query: 14 RLKRKQVIGSYQASLETLQ----ILMRYVSAIRWTSTDELIVQIKKFGNNLEKAQPYEYS 69
+L ++ GS Q ++ L+ ++ Y + T + L I L +P S
Sbjct: 151 KLANYKIFGSNQRCIDLLKTFKIVIQDYQTPYGTTLSRHLTTHINSQIAYLVSTRPLSIS 210
Query: 70 CGNVVRRVLSMIRDEIEEEQSSAEPMISSMFNLLQKPMTDTKTRKIQDNKLDVRQTIVQS 129
GN +R + ++L +TD + +++ K+D
Sbjct: 211 MGNAIR-------------------FLKLEISVLDIDLTDDEGKELLLEKID------SY 245
Query: 130 IRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKARERNNRNFTVLVTE 189
IRD I + I Q A E I D +++LT S TV L+ A+ + F V+V +
Sbjct: 246 IRDRIIIAGQV---IVQAATEKIQDGDVILTYL-HSSTVNDVLIHAKNVGKK-FRVVVVD 300
Query: 190 GFPNNTTVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFTNGGTISSTAG 249
P K L+EH IE + SA+ +M V K+ +G + +N G + S AG
Sbjct: 301 SRPEFE--GRVCLKLLTEHGIECTYVMISALSYIMQEVTKIFLGGHAMLSN-GALYSRAG 357
Query: 250 VSSVCECAREFKTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPTTEND---RVGTVA 306
S + E PV A YK + D E+ ++ +D + G +A
Sbjct: 358 TSLISLLGHESNVPVIACCESYKFTERIQLDSLVYNELAPGDQLVNMGVDDFEEKPGVLA 417
Query: 307 -------LETINPIADYIPPENIDIYITNIGGFAPSFIYRVVWDNYKQ 347
L+ ++ D PP I + + + G PS + + +KQ
Sbjct: 418 NWKSVKNLKLLSLKYDVTPPRLITVCVCEM-GLLPSTSVPAIINEFKQ 464
>At1g48970 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 756
Score = 56.2 bits (134), Expect = 7e-08
Identities = 55/250 (22%), Positives = 103/250 (41%), Gaps = 22/250 (8%)
Query: 94 PMISSMFNLLQKPMTDTKTRKIQDNKLDVRQTIVQSIRDLIDEIKNI-DEGIQQIAIELI 152
P+ SM N ++ + + ++ + + ++ I IDE I D+ I Q A+ I
Sbjct: 490 PLSMSMGNAIRFLKNQIRKLPVNLSESEAKSSLCSDIGRFIDEKTIIADKAIVQHAVTKI 549
Query: 153 HDREILLTPTPDSKTVLRFLLKARERNNRNFTVLVTEGFPNNTTVAHEFAKKLSEHDIET 212
D E+LLT V+ +L + F V++ + PN + ++L ++
Sbjct: 550 RDGEVLLTY--GFSCVVEMILLYAHEIGKKFRVVIVDSRPN--LEGQKLLRRLVTRGLDC 605
Query: 213 IVIPDSAVFALMSRVGKVIIGAKTVFTNGGTISSTAGVSSVCECAREFKTPVFAVAGLYK 272
+A+ +M +V +GA ++++NG T+ + G S + A F PV YK
Sbjct: 606 TYTHINAISYIMREATRVFLGASSIYSNG-TLYARVGTSCIAMVANAFSVPVIVCCEAYK 664
Query: 273 LSPLYPFDVEKMVEIGGSQNVL------------PTTENDRVGTVALETINPIADYIPPE 320
D E+G V T +N++ L+ +N + D P E
Sbjct: 665 FHERVLLDSICSNELGDPDAVANIPSFRTNAKHSKTMDNNK----NLQFLNLMYDSTPSE 720
Query: 321 NIDIYITNIG 330
I + +++ G
Sbjct: 721 YISMIVSDYG 730
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,191,424
Number of Sequences: 60738
Number of extensions: 833355
Number of successful extensions: 2724
Number of sequences better than 1.0e-05: 18
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2677
Number of HSP's gapped (non-prelim): 20
length of query: 356
length of database: 30,389,216
effective HSP length: 107
effective length of query: 249
effective length of database: 23,890,250
effective search space: 5948672250
effective search space used: 5948672250
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)