ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1434 good T KOG0787 Signal transduction mechanisms Dehydrogenase kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1434 505989 504571 -473
(473 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL059w [T] KOG0787 Dehydrogenase kinase 524 e-148
Hs11432626 [T] KOG0787 Dehydrogenase kinase 124 3e-28
Hs5031609 [T] KOG0787 Dehydrogenase kinase 124 4e-28
At3g06483 [T] KOG0787 Dehydrogenase kinase 94 6e-19
Hs4505693 [T] KOG0787 Dehydrogenase kinase 92 1e-18
7303893 [T] KOG0787 Dehydrogenase kinase 87 7e-17
Hs19923736 [T] KOG0787 Dehydrogenase kinase 86 9e-17
Hs4505689 [T] KOG0787 Dehydrogenase kinase 85 2e-16
SPAC644.11c [T] KOG0787 Dehydrogenase kinase 79 2e-14
Hs4885545 [T] KOG0787 Dehydrogenase kinase 78 3e-14
YIL042c [T] KOG0787 Dehydrogenase kinase 77 4e-14
CE00397 [T] KOG0787 Dehydrogenase kinase 52 1e-06
>YGL059w [T] KOG0787 Dehydrogenase kinase
Length = 445
Score = 524 bits (1350), Expect = e-148
Identities = 264/427 (61%), Positives = 325/427 (75%), Gaps = 11/427 (2%)
Query: 12 DISQVPDFSRYSATRSINELAPYISSTLSAYPTESKYINQYHYYHNDNVLVKKYLQKKPH 71
+ISQ+PDF++Y ELAPYI T+ AYP+ S+YIN HYYHN VLV+ YL++ P+
Sbjct: 19 NISQIPDFTKYCIGPVNEELAPYIMETMKAYPSNSEYINPQHYYHNRTVLVENYLKRSPN 78
Query: 72 PMSLKQLAQYYDDSSKLTKMKIISSGKFVKEELCVRIAHKLDLLQNLPFDVVNNFHFNQV 131
P+SL QLAQYYDDS+KLT+ KII+SGKFVKEEL +RIAHKL+ LQ LPF+VVNNFHF QV
Sbjct: 79 PVSLTQLAQYYDDSTKLTRTKIINSGKFVKEELVIRIAHKLNQLQQLPFNVVNNFHFVQV 138
Query: 132 YESYYNIFERFRKFPEIKDEKDNLKFCQFLHAILSDFNSLNLPHLIMGALECRILDLYPQ 191
YESYYNIFE FRK+P I+ +D +F F+ +L FN+LNLPHLIMGALEC ILDLYP+
Sbjct: 139 YESYYNIFESFRKYPTIRTLEDASQFADFIKNMLEGFNTLNLPHLIMGALECTILDLYPR 198
Query: 192 DKMDALISDLLRARISRRLIVEEHLSITSNYLSGKKENTLVLGDIFQKCNAKEYLNGARE 251
+KMD L+SDLLRARISRRLIVEEH+ T+NY SGK+ENTLVLGDIFQ+C+AK+YL A E
Sbjct: 199 EKMDQLLSDLLRARISRRLIVEEHVVYTANYTSGKEENTLVLGDIFQECSAKKYLLEASE 258
Query: 252 VCEAYINNMYFAGIKMPELIINGDTELEFYFLPSHLKFLLGEILRNSYEVTVKETIRLGL 311
+ +I +MYF I MPE II GDT+L FYFLP+HLK+LLGEILRN+YE T+K IR GL
Sbjct: 259 ESQKFIQDMYFKDIPMPEFIIEGDTQLSFYFLPTHLKYLLGEILRNTYEATMKHYIRKGL 318
Query: 312 EKAPPVTVTIISNDQSYLFRISDRGGGVPHSDKQIWSFGKSKELAKQSLDNFHHLPGLQT 371
EK P+ VT++SND+SYLFRISD+ GGV H D+ +WSFGKSKE A++SL+NFH LPGLQT
Sbjct: 319 EKPEPIIVTVVSNDESYLFRISDKAGGVLHDDENLWSFGKSKERAQESLNNFHKLPGLQT 378
Query: 372 LSLYD-----SSNGAHLKS------DRYRQTSLDRMSENNLTKGKFKVGQPLMELLKRSP 420
+S+YD + + LKS Y TSL+ MS ++ G K PL+ELL
Sbjct: 379 VSIYDEVHSHTKYNSKLKSLQSITLKPYMHTSLEPMSYPSIINGHIKYETPLIELLSGLL 438
Query: 421 RYKLGIG 427
LG+G
Sbjct: 439 DTSLGLG 445
>Hs11432626 [T] KOG0787 Dehydrogenase kinase
Length = 412
Score = 124 bits (311), Expect = 3e-28
Identities = 99/388 (25%), Positives = 165/388 (42%), Gaps = 84/388 (21%)
Query: 93 IISSGKFVKEELCVRIAHKLDLLQNLPFDVVNNFHFNQVYESYYNIFERFRKFPEIKDEK 152
++ S +++++EL VRIAH++ + LPF + N V+E Y F++ FP IKD+
Sbjct: 87 LLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQA 146
Query: 153 DNLKFCQFLHAILSDFNSLNLPHLIMGALECRILDLYPQDKMDALISDLLRARISRRLIV 212
D ++CQ + +L D + + L G E R + + + + L +R+ R++
Sbjct: 147 DEAQYCQLVRQLLDDHKDV-VTLLAEGLRESR-KHIEDEKLVRYFLDKTLTSRLGIRMLA 204
Query: 213 EEHLSITSNYLSGKKENTLVLGDIFQKCNAK----EYLNGAREVCEAYINNMYFAGIKMP 268
HL++ ++ +G I + + K ++++ AR +CE N P
Sbjct: 205 THHLAL-------HEDKPDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGN-------AP 250
Query: 269 ELIINGDTELEFYFLPSHLKFLLGEILRNSYEVTVKETIRLGLEKAPPVTVTIISNDQSY 328
+ ING F F+P L ++L E+L+N+ T++ + P V +TI +ND
Sbjct: 251 RVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPY-NVPDVVITIANNDVDL 309
Query: 329 LFRISDRGGGVPHSDKQIWSFGKSKELAKQSLDNFHHLPGLQTLSLYDSSNGAHLKSDRY 388
+ RISDRGGG+ H D
Sbjct: 310 IIRISDRGGGIAHKD--------------------------------------------- 324
Query: 389 RQTSLDRMSENNLTKGKFKVGQPLMELL----------KRSPRYKLGIGLALCKVYAEYW 438
LDR+ + + T + P + L + P + G GL + YAEY
Sbjct: 325 ----LDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQSGPMHGFGFGLPTSRAYAEYL 380
Query: 439 NGDLTVHSIQGYGTDTVLKLGNLMRHTD 466
G L + S+QG GTD L+L RH D
Sbjct: 381 GGSLQLQSLQGIGTDVYLRL----RHID 404
>Hs5031609 [T] KOG0787 Dehydrogenase kinase
Length = 412
Score = 124 bits (310), Expect = 4e-28
Identities = 99/388 (25%), Positives = 164/388 (41%), Gaps = 84/388 (21%)
Query: 93 IISSGKFVKEELCVRIAHKLDLLQNLPFDVVNNFHFNQVYESYYNIFERFRKFPEIKDEK 152
++ S +++++EL VRIAH++ + LPF + N V+E Y F++ FP IKD+
Sbjct: 87 LLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQA 146
Query: 153 DNLKFCQFLHAILSDFNSLNLPHLIMGALECRILDLYPQDKMDALISDLLRARISRRLIV 212
D ++CQ + +L D + + L G E R + + + + L +R+ R++
Sbjct: 147 DEAQYCQLVRQLLDDHKDV-VTLLAEGLRESR-KHIEDEKLVRYFLDKTLTSRLGIRMLA 204
Query: 213 EEHLSITSNYLSGKKENTLVLGDIFQKCNAK----EYLNGAREVCEAYINNMYFAGIKMP 268
HL++ ++ G I + + K ++++ AR +CE N P
Sbjct: 205 THHLAL-------HEDKPDFFGIICTRLSPKKIIEKWVDFARRLCEHKYGN-------AP 250
Query: 269 ELIINGDTELEFYFLPSHLKFLLGEILRNSYEVTVKETIRLGLEKAPPVTVTIISNDQSY 328
+ ING F F+P L ++L E+L+N+ T++ + P V +TI +ND
Sbjct: 251 RVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPY-NVPDVVITIANNDVDL 309
Query: 329 LFRISDRGGGVPHSDKQIWSFGKSKELAKQSLDNFHHLPGLQTLSLYDSSNGAHLKSDRY 388
+ RISDRGGG+ H D
Sbjct: 310 IIRISDRGGGIAHKD--------------------------------------------- 324
Query: 389 RQTSLDRMSENNLTKGKFKVGQPLMELL----------KRSPRYKLGIGLALCKVYAEYW 438
LDR+ + + T + P + L + P + G GL + YAEY
Sbjct: 325 ----LDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQSGPMHGFGFGLPTSRAYAEYL 380
Query: 439 NGDLTVHSIQGYGTDTVLKLGNLMRHTD 466
G L + S+QG GTD L+L RH D
Sbjct: 381 GGSLQLQSLQGIGTDVYLRL----RHID 404
>At3g06483 [T] KOG0787 Dehydrogenase kinase
Length = 380
Score = 93.6 bits (231), Expect = 6e-19
Identities = 99/415 (23%), Positives = 171/415 (40%), Gaps = 75/415 (18%)
Query: 62 VKKYLQKKPHPMSLKQLAQYYDDSSKLTKMKIISSGKFVKEELCVRIAHKLDLLQNLPFD 121
V K+ K +SL+ + ++ SK T+ ++ S +F+ +EL +R+A + LQ LP+
Sbjct: 18 VHKWGCMKQTGVSLRYMMEF---GSKPTERNLLISAQFLHKELPIRVARRAIELQTLPYG 74
Query: 122 VVNNFHFNQVYESYYNIFERFRKFPEIKDEKDNLKFCQFLHAILSDFNSLNLPHLIMGAL 181
+ + +V + Y F R FPEIKD D F Q + A+ N++ +P + +G
Sbjct: 75 LSDKPAVLKVRDWYLESFRDMRAFPEIKDSGDEKDFTQMIKAVKVRHNNV-VPMMALGVN 133
Query: 182 ECRI-LDLYPQDKMDALISDLLRARISRRLIVEEHLSITSNYLSGKKENTLVLGDIFQKC 240
+ + ++ D++ + +RI R+++ +H+ L +G I K
Sbjct: 134 QLKKGMNSGNLDEIHQFLDRFYLSRIGIRMLIGQHVE-----LHNPNPPLHTVGYIHTKM 188
Query: 241 NAKEYLNGAREVCEAYINNMYFAGIKMPELIINGDTELEFYFLPSHLKFLLGEILRNSYE 300
+ E A E + Y + PE+ I GD F ++P+HL ++ E+++NS
Sbjct: 189 SPMEVARNASEDARSICFREYGSA---PEINIYGDPSFTFPYVPTHLHLMMYELVKNSLR 245
Query: 301 VTVKETIRLGLEKAPPVTVTI--------ISNDQSYLFR------ISDRGGGVPHSDKQI 346
V+E APP+ + + I +S L R +SD GGG+ S
Sbjct: 246 -AVQERFVDSDRVAPPIRIIVADGIEDVTIKPFRSLLHRFDPIIVVSDEGGGIARSG--- 301
Query: 347 WSFGKSKELAKQSLDNFHHLPGLQTLSLYDSSNGAHLKSDRYRQTSLDRMSENNLTKGKF 406
LP + T + N D +++ +T +
Sbjct: 302 -------------------LPRIFTYLYSTARNPLEEDVDL-------GIADVPVTMAGY 335
Query: 407 KVGQPLMELLKRSPRYKLGIGLALCKVYAEYWNGDLTVHSIQGYGTDTVLKLGNL 461
G P+ L YA Y+ GDL + S++GYGTD L L L
Sbjct: 336 GYGLPISRL------------------YARYFGGDLQIISMEGYGTDAYLHLSRL 372
>Hs4505693 [T] KOG0787 Dehydrogenase kinase
Length = 411
Score = 92.4 bits (228), Expect = 1e-18
Identities = 94/408 (23%), Positives = 161/408 (39%), Gaps = 78/408 (19%)
Query: 62 VKKYLQKKPHPMSLKQLAQYYDDSSKLTKMKIISSGKFVKEELCVRIAHKLDLLQNLPFD 121
V+ + + P P+S+KQL + +++ +S F+++EL VR+A+ L + LP
Sbjct: 24 VEHFSRYSPSPLSMKQLLDFGSENACER-----TSFAFLRQELPVRLANILKEIDILPTQ 78
Query: 122 VVNNFHFNQVYESYYNIFERFRKFPEIKDEKDNLKFCQFLHAILSDFNSLN--LPHLIMG 179
+VN V Y +F E K D F+ ++ N + +P + G
Sbjct: 79 LVNTSSVQLVKSWYIQSLMDLVEFHE-KSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQG 137
Query: 180 ALECR---ILDLYPQDKMDALISDLLRARISRRLIVEEHLSITSNYLSGKKENTLVLGDI 236
+E + +D + + RIS R+++ +H+ I S+ +G + +G I
Sbjct: 138 IIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSH---IGSI 194
Query: 237 FQKCNAKEYLNGAREVCEAYINNMYFAGIKMPELIING---DTELEFYFLPSHLKFLLGE 293
C+ + A E + Y + ++ +NG D + ++PSHL +L E
Sbjct: 195 DPNCDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFE 254
Query: 294 ILRNSYEVTVKETIRLGLEKAP---PVTVTIISNDQSYLFRISDRGGGVPHSDKQIWSFG 350
+ +N+ TV+ E P P+ V ++ + +ISDRGGGVP
Sbjct: 255 LFKNAMRATVEHQ-----ENQPSLTPIEVIVVLGKEDLTIKISDRGGGVP---------- 299
Query: 351 KSKELAKQSLDNFHHLPGLQTLSLYDSSNGAHLKSDRYRQTSLDRMSENNLTKGKFKVGQ 410
L + L Y S D R L F G
Sbjct: 300 ---------------LRIIDRLFSYTYSTAPTPVMDNSRNAPL----------AGFGYGL 334
Query: 411 PLMELLKRSPRYKLGIGLALCKVYAEYWNGDLTVHSIQGYGTDTVLKL 458
P+ L YA+Y+ GDL ++S+ GYGTD ++ L
Sbjct: 335 PISRL------------------YAKYFQGDLNLYSLSGYGTDAIIYL 364
>7303893 [T] KOG0787 Dehydrogenase kinase
Length = 413
Score = 86.7 bits (213), Expect = 7e-17
Identities = 89/410 (21%), Positives = 172/410 (41%), Gaps = 75/410 (18%)
Query: 70 PHPMSLKQLAQYYDDSSKLTKMKIISSGKFVKEELCVRIAHKLDLLQNLPFDVVNNFHFN 129
P P+S+KQ + ++ + S F+++EL VR+A+ + + LP ++++ +
Sbjct: 30 PSPLSIKQFMDFGQNACEK------KSYIFLRKELPVRLANIMKEIALLPDNLLHTRSVS 83
Query: 130 QVYESYYNIFERFRKFPEIKDEKDNL-KFCQFLHAILSDFNSLNLPHLIMGALECRI--- 185
+V Y FE + + + DNL KF L I + N + + + G +E +
Sbjct: 84 EVSSWYVKSFEDVLVYEKAEPTHDNLQKFVADLDLIRNRHNDV-VQTMAQGVIEMKENEG 142
Query: 186 --LDLYPQDKMDALISDLLRARISRRLIVEEH-LSITSNYLSGKKENTLVLGDIFQKCNA 242
+D + + + L +RIS R+++ +H L N +G + +G + C+
Sbjct: 143 GQVDAPTESSIQYFLDRLYMSRISIRMLINQHTLLFGGNPHAGGRH----IGCLDPACDL 198
Query: 243 KEYLNGARE----VCEAYINNMYFAGIKMPELIINGDTELEFYFLPSHLKFLLGEILRNS 298
+ + A E +C+ Y I+ + + ++PSHL ++L E+ +NS
Sbjct: 199 SDVVRDAYENARFLCDQYYLTSPALEIQQHSSEPGDNLPIRTVYVPSHLYYMLFELFKNS 258
Query: 299 YEVTVKETIRLGLEKAPPVTVTIISNDQSYLFRISDRGGGVPHSDKQIWSFGKSKELAKQ 358
V+ + PP+ V I + +ISD+GGG+P S
Sbjct: 259 MRAVVEHHGHDNNDTLPPLKVAICKGKEDICVKISDQGGGIPRS---------------- 302
Query: 359 SLDNFHHLPGLQTLSLYDSSNGAHLKSDRYRQTSLDRMSENNLTKGKFKVGQPLMELLKR 418
QT L+ +Y ++ + S+++ L
Sbjct: 303 -----------QTDQLF-----------KYMYSTAPQPSKSD---------------LHT 325
Query: 419 SPRYKLGIGLALCKVYAEYWNGDLTVHSIQGYGTDTVLKLGNLMRHTDKL 468
P G GL + ++YA Y++GD+ + S +G+GTD ++ L L ++L
Sbjct: 326 VPLAGYGYGLPISRLYARYFHGDIVLLSCEGFGTDAIIYLKALSDEANEL 375
>Hs19923736 [T] KOG0787 Dehydrogenase kinase
Length = 407
Score = 86.3 bits (212), Expect = 9e-17
Identities = 98/411 (23%), Positives = 170/411 (40%), Gaps = 84/411 (20%)
Query: 62 VKKYLQKKPHPMSLKQLAQYYDDSSKLTKMKIISSGKFVKEELCVRIAHKLDLLQNLPFD 121
++ + + P P+S+KQ + S+ K +S F+++EL VR+A+ + + LP
Sbjct: 20 IEHFSKFSPSPLSMKQFLDF-GSSNACEK----TSFTFLRQELPVRLANIMKEINLLPDR 74
Query: 122 VVNNFHFNQVYESYYNIFERFRKFPEIKDEKDNLKFCQFLHAILSDFNSLN--LPHLIMG 179
V++ V Y +F + KD +D+ QF A+++ N N +P + G
Sbjct: 75 VLSTPSVQLVQSWYVQSLLDIMEFLD-KDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQG 133
Query: 180 ALECRILDLYPQD-----KMDALISDLLRARISRRLIVEEHLSITSNYLSGKKENTLVLG 234
LE + D Y D + + +RIS R+++ +H I S + +G
Sbjct: 134 VLEYK--DTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDG--STNPAHPKHIG 189
Query: 235 DIFQKCNAKEYLNGAREVCEAYINNMYFAGIKMPELII------NGDTELEFYFLPSHLK 288
I CN E + A ++ + + Y A P+L I N + ++PSHL
Sbjct: 190 SIDPNCNVSEVVKDAYDMAKLLCDKYYMAS---PDLEIQEINAANSKQPIHMVYVPSHLY 246
Query: 289 FLLGEILRNSYEVTVKETIRLGLEKAPPVTVTIISNDQSYLFRISDRGGGVP-HSDKQIW 347
+L E+ +N+ TV+ + PP+ V + ++ ++SDRGGGVP ++++
Sbjct: 247 HMLFELFKNAMRATVESHESSLI--LPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLF 304
Query: 348 SFGKSKELAKQSLDNFHHLPGLQTLSLYDSSNGAHLKSDRYRQTSLDRMSENNLTKGKFK 407
S+ S Q PG + G L F
Sbjct: 305 SYMYSTAPTPQ--------PG---------TGGTPLAG--------------------FG 327
Query: 408 VGQPLMELLKRSPRYKLGIGLALCKVYAEYWNGDLTVHSIQGYGTDTVLKL 458
G P+ L YA+Y+ GDL + S++G+GTD V+ L
Sbjct: 328 YGLPISRL------------------YAKYFQGDLQLFSMEGFGTDAVIYL 360
>Hs4505689 [T] KOG0787 Dehydrogenase kinase
Length = 436
Score = 85.1 bits (209), Expect = 2e-16
Identities = 93/415 (22%), Positives = 167/415 (39%), Gaps = 75/415 (18%)
Query: 65 YLQKKPHPMSLKQLAQYYDDSSKLTKMKIISSGKFVKEELCVRIAHKLDLLQNLPFDVVN 124
Y + P P+S+KQ + D S K +S F+++EL VR+A+ + + LP +++
Sbjct: 49 YARFSPSPLSMKQ---FLDFGSVNACEK--TSFMFLRQELPVRLANIMKEISLLPDNLLR 103
Query: 125 NFHFNQVYESYYNIFERFRKFPEIKDEKDNLKFCQFLHAILSDFNSLN--LPHLIMGALE 182
V Y + F + K +D F ++ N N +P + G +E
Sbjct: 104 TPSVQLVQSWYIQSLQELLDFKD-KSAEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVIE 162
Query: 183 CRI---LDLYPQDKMDALISDLLRARISRRLIVEEHLSITSNYLSGKKENTLVLGDIFQK 239
+ +D + + +RIS R+++ +H + G + +G I
Sbjct: 163 YKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHIGSINPN 222
Query: 240 CNAKEYLN----GAREVCEAYINNMYFAGIKMPELIINGDTE-LEFYFLPSHLKFLLGEI 294
CN E + AR +C+ Y N +++ EL + ++ ++PSHL ++ E+
Sbjct: 223 CNVLEVIKDGYENARRLCDLYYINS--PELELEELNAKSPGQPIQVVYVPSHLYHMVFEL 280
Query: 295 LRNSYEVTVKETIRLGLEKAPPVTVTIISNDQSYLFRISDRGGGVPHSDKQIWSFGKSKE 354
+N+ T++ G+ PP+ V + ++ ++SDRGGGVP
Sbjct: 281 FKNAMRATMEHHANRGVY--PPIQVHVTLGNEDLTVKMSDRGGGVP-------------- 324
Query: 355 LAKQSLDNFHHLPGLQTLSLYDSSNGAHLKSDRYRQTSLDRMSENNLTKGKFKVGQPLME 414
L + L Y S + + R L F G P+
Sbjct: 325 -----------LRKIDRLFNYMYSTAPRPRVETSRAVPL----------AGFGYGLPISR 363
Query: 415 LLKRSPRYKLGIGLALCKVYAEYWNGDLTVHSIQGYGTDTVLKLGNLMRHTDKLQ 469
L YA+Y+ GDL ++S++GYGTD V+ + L TD ++
Sbjct: 364 L------------------YAQYFQGDLKLYSLEGYGTDAVIYIKAL--STDSIE 398
>SPAC644.11c [T] KOG0787 Dehydrogenase kinase
Length = 425
Score = 78.6 bits (192), Expect = 2e-14
Identities = 69/267 (25%), Positives = 114/267 (41%), Gaps = 55/267 (20%)
Query: 204 ARISRRLIVEEHLSITSNYLSGKKENTLVLGDIFQKCNAKEYLNGAREVCEAYINNMYFA 263
+RI R+++ +++++ S +EN +G I + N + + GA E + YI + +
Sbjct: 213 SRIGIRMLLGQYIALVSE---PPREN--YVGVISTRANIYQIIEGAAENAK-YICRLAYG 266
Query: 264 GIKMPELIINGDTELEFYFLPSHLKFLLGEILRNSYEVTVKETIRLGLEKAPPVTVTIIS 323
+ PE+ I D LE ++ SHL + EIL+NS TV E + + PP+ V +
Sbjct: 267 LFEAPEIQIICDPSLEMMYVESHLNHAVFEILKNSLRATV-EFHGVDSDFFPPIKVIVAK 325
Query: 324 NDQSYLFRISDRGGGVPHSD-KQIWSFGKSKELAKQSLDNFHHLPGLQTLSLYDSSNGAH 382
+ +ISD GGG+ + +WS+ A +L + H
Sbjct: 326 GQEDITIKISDEGGGISRRNIPLVWSY--MFTTASPTLTDDPH----------------- 366
Query: 383 LKSDRYRQTSLDRMSENNLTKGKFKVGQPLMELLKRSPRYKLGIGLALCKVYAEYWNGDL 442
D +S N+ T P G GL L ++Y Y+ GDL
Sbjct: 367 -----------DIVSANSTT-----------------PMAGFGFGLPLARLYTRYFGGDL 398
Query: 443 TVHSIQGYGTDTVLKLGNLMRHTDKLQ 469
+ S++GYGTD + L L + LQ
Sbjct: 399 ELISMEGYGTDVYIHLNRLCESAEPLQ 425
>Hs4885545 [T] KOG0787 Dehydrogenase kinase
Length = 406
Score = 78.2 bits (191), Expect = 3e-14
Identities = 95/410 (23%), Positives = 158/410 (38%), Gaps = 80/410 (19%)
Query: 62 VKKYLQKKPHPMSLKQLAQYYDDSSKLTKMKIISSGKFVKEELCVRIAHKLDLLQNLPFD 121
+++Y + P P+S+KQ + D++ +S F+++EL VR+A+ + + LP +
Sbjct: 16 IERYSRFSPSPLSIKQFLDFGRDNACEK-----TSYMFLRKELPVRLANTMREVNLLPDN 70
Query: 122 VVNNFHFNQVY----ESYYNIFERFRKFPEIKDEKDNLKFCQFLHAILSDFNSLNLPHLI 177
++N V +S+ + E K PE DN F Q L + + N + +P +
Sbjct: 71 LLNRPSVGLVQSWYMQSFLELLEYENKSPEDPQVLDN--FLQVLIKVRNRHNDV-VPTMA 127
Query: 178 MGALECRI---LDLYPQDKMDALISDLLRARISRRLIVEEHLSITSNYLSGKKENTLV-- 232
G +E + D + + + RIS R+++ +H L G N +
Sbjct: 128 QGVIEYKEKFGFDPFISTNIQYFLDRFYTNRISFRMLINQH-----TLLFGGDTNPVHPK 182
Query: 233 -LGDIFQKCNAKEYLNGAREVCEAYINNMYFAGIKMPELIING---DTELEFYFLPSHLK 288
+G I CN + + A E + Y ++ N D ++ ++PSHL
Sbjct: 183 HIGSIDPTCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFNAKAPDKPIQVVYVPSHLF 242
Query: 289 FLLGEILRNSYEVTVKETIRLGLEKAPPVTVTIISNDQSYLFRISDRGGGVPHSDKQIWS 348
+L E+ +NS TV E E P V + + +ISD GGGVP
Sbjct: 243 HMLFELFKNSMRATV-ELYEDRKEGYPAVKTLVTLGKEDLSIKISDLGGGVP-------- 293
Query: 349 FGKSKELAKQSLDNFHHLPGLQTLSLYDSSNGAHLKSDRYRQTSLDRMSENNLTKGKFKV 408
L + L Y S + R L F
Sbjct: 294 -----------------LRKIDRLFNYMYSTAPRPSLEPTRAAPL----------AGFGY 326
Query: 409 GQPLMELLKRSPRYKLGIGLALCKVYAEYWNGDLTVHSIQGYGTDTVLKL 458
G P+ L YA Y+ GDL ++S++G GTD V+ L
Sbjct: 327 GLPISRL------------------YARYFQGDLKLYSMEGVGTDAVIYL 358
>YIL042c [T] KOG0787 Dehydrogenase kinase
Length = 394
Score = 77.4 bits (189), Expect = 4e-14
Identities = 90/425 (21%), Positives = 168/425 (39%), Gaps = 79/425 (18%)
Query: 44 TESKYINQYHYYHNDNVLVKKYLQKKPHPMSLKQLAQYYDDSSKLTK-MKIISSGKFVKE 102
++ + Y N +L++ Y K P++ + QY +K + M I + +
Sbjct: 27 SQLSFDQHYKIRSNIELLIQDYASKPIAPLNYEYFLQYRPPLTKKEEYMLTIKTINLLLS 86
Query: 103 ELCVRIAHKLDLLQNLPFDVVNNFHFNQVYESYYNIFERFRKFPEIKDEKDNLKFCQFLH 162
C R L+ +Q LP++ V N H + Y + + + K
Sbjct: 87 LTCKR----LNAIQRLPYNAVINPHIERTNSLYLKSLQTLLSIAYPYELHNPPKIQAKFT 142
Query: 163 AILSDFNSLNLPHLIMGALECRILDLYPQDKMDALISDLLRARISRRLIVEEHLSI---- 218
+L D + L G E I YP+ ++ ++ L+ RI+ +L+V +LS+
Sbjct: 143 ELLDDHEDA-IVVLAKGLQE--IQSCYPKFQISQFLNFHLKERITMKLLVTHYLSLMAQN 199
Query: 219 ---TSNYLSGKKENTLVLGDIFQKCNAKEYLNGAREVCEAYINNMYFAGIKMPELIINGD 275
T+ + G L + + + + +Y+N ++C N + P LI
Sbjct: 200 KGDTNKRMIGILHRDLPIAQLIK--HVSDYVN---DICFVKFNTQ-----RTPVLIHPPS 249
Query: 276 TELEFYFLPSHLKFLLGEILRNSYEVTVKETIRLGLEKAPPVTVTIISNDQSYLF-RISD 334
++ F +P L++++ E+ +N++E I LG E P + + ++ D L+ RI D
Sbjct: 250 QDITFTCIPPILEYIMTEVFKNAFEAQ----IALGKEHMP-IEINLLKPDDDELYLRIRD 304
Query: 335 RGGGV-PHSDKQIWSFGKSKELAKQSLDNFHHLPGLQTLSLYDSSNGAHLKSDRYRQTSL 393
GGG+ P + ++++ S + + LPG Q
Sbjct: 305 HGGGITPEVEALMFNYSYSTHTQQSADSESTDLPGEQI---------------------- 342
Query: 394 DRMSENNLTKGKFKVGQPLMELLKRSPRYKLGIGLALCKVYAEYWNGDLTVHSIQGYGTD 453
NN++ +G GL +CK Y E + G + V S+ G+GTD
Sbjct: 343 -----NNVS--------------------GMGFGLPMCKTYLELFGGKIDVQSLLGWGTD 377
Query: 454 TVLKL 458
+KL
Sbjct: 378 VYIKL 382
>CE00397 [T] KOG0787 Dehydrogenase kinase
Length = 401
Score = 52.4 bits (124), Expect = 1e-06
Identities = 66/290 (22%), Positives = 118/290 (39%), Gaps = 28/290 (9%)
Query: 70 PHPMSLKQLAQYYDD--SSKLTKMKIISSGK---------FVKEELCVRIAHKLDLLQNL 118
P SL + YY S LT + + G+ F+K EL VR+A+ + L
Sbjct: 10 PFVGSLAKKLDYYSQFQPSSLTIQQYLDFGRIGTSANSYTFLKNELLVRLANIMQEFTLL 69
Query: 119 PFDVVNNFHFNQVYESYYNIFERFRKFPEIKDEKDNL-KFCQFLHAILSDFNSLNLPHLI 177
P ++ V Y FE F + + +F L +L + + +
Sbjct: 70 PPKLLQMPSSKMVSNWYAESFEDLLLFEASDSSPEQVARFNDQLTVVLKRHAHV-VETMA 128
Query: 178 MGALECRI---LDLYPQDKMDALISDLLRARISRRLIVEEHLSITSNYLSGKKENTLVLG 234
G +E R +D+ + + + RIS R++ +HL + N L E+ +G
Sbjct: 129 EGLIELRESDGVDIASEKGIQYFLDRFYINRISIRMLQNQHLVVFGNVLP---ESPRHVG 185
Query: 235 DIFQKCNAKEYL----NGAREVCEAYINNMYFAGIKMPELIINGDTELEFYFLPSHLKFL 290
I C+ + + AR +C+ Y ++M + G + +PSHL +
Sbjct: 186 CIDPACDVESVVYDAFENARFLCDRYYLTSPSMKLEMHNAVEKGKP-ISIVAVPSHLYHM 244
Query: 291 LGEILRNSYEVTVKETIRLGLEK-APPVTVTIISNDQSYLFRISDRGGGV 339
+ E+ +N+ TV+ G++ P + V ++ + +I DRGGGV
Sbjct: 245 MFELFKNAMRATVEYH---GVDDDLPDIKVYVVKGQEDLSIKICDRGGGV 291
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.137 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,889,723
Number of Sequences: 60738
Number of extensions: 1289348
Number of successful extensions: 3418
Number of sequences better than 1.0e-05: 12
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 3390
Number of HSP's gapped (non-prelim): 24
length of query: 473
length of database: 30,389,216
effective HSP length: 110
effective length of query: 363
effective length of database: 23,708,036
effective search space: 8606017068
effective search space used: 8606017068
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)