ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1460 check: MH C KOG0369 Energy production and conversion Pyruvate carboxylase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1460 515991 512473 -1173
(1173 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR218c [C] KOG0369 Pyruvate carboxylase 1953 0.0
YGL062w [C] KOG0369 Pyruvate carboxylase 1946 0.0
SPBC17G9.11c [C] KOG0369 Pyruvate carboxylase 1483 0.0
CE09072 [C] KOG0369 Pyruvate carboxylase 1175 0.0
7303838 [C] KOG0369 Pyruvate carboxylase 1160 0.0
Hs4505627 [C] KOG0369 Pyruvate carboxylase 1137 0.0
At5g35360 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-c... 333 7e-91
At1g03090 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-c... 314 6e-85
7302098 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-con... 313 1e-84
Hs13518228 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-... 312 2e-84
CE09857 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-con... 309 1e-83
Hs4557833 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-c... 305 2e-82
CE04451 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-con... 300 7e-81
YBR208c_2 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-c... 267 6e-71
7304119 [I] KOG0368 Acetyl-CoA carboxylase 199 2e-50
SPAC56E4.04c [I] KOG0368 Acetyl-CoA carboxylase 193 2e-48
YMR207c [I] KOG0368 Acetyl-CoA carboxylase 187 1e-46
Hs4826637 [I] KOG0368 Acetyl-CoA carboxylase 186 2e-46
YNR016c [I] KOG0368 Acetyl-CoA carboxylase 181 5e-45
At1g36160 [I] KOG0368 Acetyl-CoA carboxylase 177 9e-44
At1g36180 [I] KOG0368 Acetyl-CoA carboxylase 177 1e-43
CE14734 [I] KOG0368 Acetyl-CoA carboxylase 170 1e-41
Hs4501855 [I] KOG0368 Acetyl-CoA carboxylase 169 2e-41
CE20115 [I] KOG0368 Acetyl-CoA carboxylase 168 4e-41
SPBC215.08c [R] KOG0370 Multifunctional pyrimidine synthesis pro... 58 1e-07
Hs18105007 [R] KOG0370 Multifunctional pyrimidine synthesis prot... 57 2e-07
YJL130c [R] KOG0370 Multifunctional pyrimidine synthesis protein... 52 4e-06
>YBR218c [C] KOG0369 Pyruvate carboxylase
Length = 1180
Score = 1953 bits (5059), Expect = 0.0
Identities = 962/1168 (82%), Positives = 1056/1168 (90%), Gaps = 1/1168 (0%)
Query: 2 SSQLAGLRDNSNLMGEKNKLLVANRGEIPIRIFRTAHELSMKTVAIYSHEDRLSMHRLKA 61
S +LAGLRDN +L+GEKNK+LVANRGEIPIRIFR+AHELSM+T+AIYSHEDRLSMHRLKA
Sbjct: 4 SKKLAGLRDNFSLLGEKNKILVANRGEIPIRIFRSAHELSMRTIAIYSHEDRLSMHRLKA 63
Query: 62 DEAYVIGEQGKYTPVGAYLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITW 121
DEAYVIGE+G+YTPVGAYLA+DEII IAK H V+FIHPGYGFLSENSEFA+KV +GITW
Sbjct: 64 DEAYVIGEEGQYTPVGAYLAMDEIIEIAKKHKVDFIHPGYGFLSENSEFADKVVKAGITW 123
Query: 122 VGPPAAVIDSVGDKVSARNLAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFX 181
+GPPA VIDSVGDKVSAR+LA +ANVP VPGTPGPIETV+EA FV++YG+PVIIKAAF
Sbjct: 124 IGPPAEVIDSVGDKVSARHLAARANVPTVPGTPGPIETVQEALDFVNEYGYPVIIKAAFG 183
Query: 182 XXXXXXXXXXXXDDISDAFQRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVV 241
DD++DAFQRA SEA TAFGNGTCF+ERFLDKPKHIEVQLLADN+GNVV
Sbjct: 184 GGGRGMRVVREGDDVADAFQRATSEARTAFGNGTCFVERFLDKPKHIEVQLLADNHGNVV 243
Query: 242 HLFERDCSVQRRHQKVVEVAPAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVDNQN 301
HLFERDCSVQRRHQKVVEVAPAKTLP EVRDAILTDAVKLAK GYRNAGTAEFLVDNQN
Sbjct: 244 HLFERDCSVQRRHQKVVEVAPAKTLPREVRDAILTDAVKLAKVCGYRNAGTAEFLVDNQN 303
Query: 302 RHYFIEINPRIQVEHTITEEITXXXXXXXXXXXXXXXTLEQLGLMQDKITTRGFAIQCRI 361
RHYFIEINPRIQVEHTITEEIT TL QLGL+QDKITTRGF+IQCRI
Sbjct: 304 RHYFIEINPRIQVEHTITEEITGIDIVSAQIQIAAGATLTQLGLLQDKITTRGFSIQCRI 363
Query: 362 TTEDPSKNFQPDTGRIDVYRSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEI 421
TTEDPSKNFQPDTGR++VYRSAGGNGVRLDGGNA+AG+ ISPHYDSMLVKCSCSGSTYEI
Sbjct: 364 TTEDPSKNFQPDTGRLEVYRSAGGNGVRLDGGNAYAGATISPHYDSMLVKCSCSGSTYEI 423
Query: 422 VRRKMLRALIEFRIRGVKTNIPFLLTLLTHPVFKSGEYWTTFIDDTPQLFEMVSSQNRAQ 481
VRRKM+RALIEFRIRGVKTNIPFLLTLLT+PVF G YWTTFIDDTPQLF+MVSSQNRAQ
Sbjct: 424 VRRKMIRALIEFRIRGVKTNIPFLLTLLTNPVFIEGTYWTTFIDDTPQLFQMVSSQNRAQ 483
Query: 482 KLLHYLADLAVNGSSIKGQIGLPKLTTHPTIPHLHNEDGSLVDVS-AKPPAGWRDVLLDY 540
KLLHYLADLAVNGSSIKGQIGLPKL ++P++PHLH+ G++++V+ + PP+GWR VLL+
Sbjct: 484 KLLHYLADLAVNGSSIKGQIGLPKLKSNPSVPHLHDAQGNVINVTKSAPPSGWRQVLLEK 543
Query: 541 GPEEFAKQVRKFNGTLLMDTTWRDAHQSLLATRVRTYDLAAIAPTTAHAMSGAFALECWG 600
GP EFAKQVR+FNGTLLMDTTWRDAHQSLLATRVRT+DLA IAPTTAHA++GAFALECWG
Sbjct: 544 GPSEFAKQVRQFNGTLLMDTTWRDAHQSLLATRVRTHDLATIAPTTAHALAGAFALECWG 603
Query: 601 GATFDVSMRFLHEDPWERLRTLRKLVPNIPFQMLLRGANGVAYSSLPDNAIDHFVKQAKD 660
GATFDV+MRFLHEDPWERLR LR LVPNIPFQMLLRGANGVAYSSLPDNAIDHFVKQAKD
Sbjct: 604 GATFDVAMRFLHEDPWERLRKLRSLVPNIPFQMLLRGANGVAYSSLPDNAIDHFVKQAKD 663
Query: 661 NGVDIFRVFDALNDLEQLXXXXXXXXXXXXXXXXTICYSGDMLAPGKKYNLDYYLDITEK 720
NGVDIFRVFDALNDLEQL T+CYSGDML PGKKYNLDYYL++ EK
Sbjct: 664 NGVDIFRVFDALNDLEQLKVGVNAVKKAGGVVEATVCYSGDMLQPGKKYNLDYYLEVVEK 723
Query: 721 IVNSGTHILGIKDMAGTLKPSAARLLIGSIRAKYPELPIHVHTHDSAGTGVASMAACALS 780
IV GTHILGIKDMAGT+KP+AA+LLIGS+R +YP+LPIHVH+HDSAGT VASM ACAL+
Sbjct: 724 IVQMGTHILGIKDMAGTMKPAAAKLLIGSLRTRYPDLPIHVHSHDSAGTAVASMTACALA 783
Query: 781 GADVVDVATNSMSGLTSQPSINALLAALDGEIDNNVNVGYVRELDAYWAEMRLLYSCFEA 840
GADVVDVA NSMSGLTSQPSINALLA+L+G ID +NV +VRELDAYWAEMRLLYSCFEA
Sbjct: 784 GADVVDVAINSMSGLTSQPSINALLASLEGNIDTGINVEHVRELDAYWAEMRLLYSCFEA 843
Query: 841 DLKGPDPEVYVHEIPGGQLTNLLFQAQQLGLGEKWAETKRAYREANLLLGDLVKVTPTSK 900
DLKGPDPEVY HEIPGGQLTNLLFQAQQLGLGE+WAETKRAYREAN LLGD+VKVTPTSK
Sbjct: 844 DLKGPDPEVYQHEIPGGQLTNLLFQAQQLGLGEQWAETKRAYREANYLLGDIVKVTPTSK 903
Query: 901 VVGDLAQFMVSNKLTSDDVRRLASSLDFPDSVMDFFEGLIGQPYGGFPEPLRTDVLRNKR 960
VVGDLAQFMVSNKLTSDD+RRLA+SLDFPDSVMDFFEGLIGQPYGGFPEPLR+DVLRNKR
Sbjct: 904 VVGDLAQFMVSNKLTSDDIRRLANSLDFPDSVMDFFEGLIGQPYGGFPEPLRSDVLRNKR 963
Query: 961 RKLTQRPGLELAPFELEKIKEDLSTRFSDIDECDVASYNMYPKVYEDFRKIKEKYGDLSV 1020
RKLT RPGLEL PF+LEKI+EDL RF DIDECDVASYNMYP+VYEDF+KI+E YGDLSV
Sbjct: 964 RKLTCRPGLELEPFDLEKIREDLQNRFGDIDECDVASYNMYPRVYEDFQKIRETYGDLSV 1023
Query: 1021 LPTKNFLSPPVIGEEIVVTIEQGKTLIIKPQAIGDLNKETGIREVYFELNGELRKVSVAD 1080
LPTKNFL+P EEI VTIEQGKTLIIK QA+GDLNK+TG REVYFELNGELRK+ VAD
Sbjct: 1024 LPTKNFLAPAEPDEEIEVTIEQGKTLIIKLQAVGDLNKKTGQREVYFELNGELRKIRVAD 1083
Query: 1081 RSQKVESVSKPKADAHDPFQIGSPMAGVVVEVKVHKGSLIAKGQPVAVLSAMKMEMVISS 1140
+SQ ++SV+KPKAD HD QIG+PMAGV++EVKVHKGSL+ KG+ +AVLSAMKMEMV+SS
Sbjct: 1084 KSQNIQSVAKPKADVHDTHQIGAPMAGVIIEVKVHKGSLVKKGESIAVLSAMKMEMVVSS 1143
Query: 1141 PADGQVKEVLVKDGENVDASDLLVVLEE 1168
PADGQVK+V +KDGE+VDASDLLVVLEE
Sbjct: 1144 PADGQVKDVFIKDGESVDASDLLVVLEE 1171
>YGL062w [C] KOG0369 Pyruvate carboxylase
Length = 1178
Score = 1946 bits (5042), Expect = 0.0
Identities = 963/1166 (82%), Positives = 1051/1166 (89%), Gaps = 1/1166 (0%)
Query: 4 QLAGLRDNSNLMGEKNKLLVANRGEIPIRIFRTAHELSMKTVAIYSHEDRLSMHRLKADE 63
+ AGLRDN NL+GEKNK+LVANRGEIPIRIFRTAHELSM+TVAIYSHEDRLS H+ KADE
Sbjct: 5 KFAGLRDNFNLLGEKNKILVANRGEIPIRIFRTAHELSMQTVAIYSHEDRLSTHKQKADE 64
Query: 64 AYVIGEQGKYTPVGAYLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVG 123
AYVIGE G+YTPVGAYLAIDEII+IA+ H V+FIHPGYGFLSENSEFA+KV +GITW+G
Sbjct: 65 AYVIGEVGQYTPVGAYLAIDEIISIAQKHQVDFIHPGYGFLSENSEFADKVVKAGITWIG 124
Query: 124 PPAAVIDSVGDKVSARNLAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFXXX 183
PPA VIDSVGDKVSARNLA KANVP VPGTPGPIETVEEA FV++YG+PVIIKAAF
Sbjct: 125 PPAEVIDSVGDKVSARNLAAKANVPTVPGTPGPIETVEEALDFVNEYGYPVIIKAAFGGG 184
Query: 184 XXXXXXXXXXDDISDAFQRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHL 243
DD++DAFQRA SEA TAFGNGTCF+ERFLDKPKHIEVQLLADN+GNVVHL
Sbjct: 185 GRGMRVVREGDDVADAFQRATSEARTAFGNGTCFVERFLDKPKHIEVQLLADNHGNVVHL 244
Query: 244 FERDCSVQRRHQKVVEVAPAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVDNQNRH 303
FERDCSVQRRHQKVVEVAPAKTLP EVRDAILTDAVKLAKE GYRNAGTAEFLVDNQNRH
Sbjct: 245 FERDCSVQRRHQKVVEVAPAKTLPREVRDAILTDAVKLAKECGYRNAGTAEFLVDNQNRH 304
Query: 304 YFIEINPRIQVEHTITEEITXXXXXXXXXXXXXXXTLEQLGLMQDKITTRGFAIQCRITT 363
YFIEINPRIQVEHTITEEIT +L QLGL QDKITTRGFAIQCRITT
Sbjct: 305 YFIEINPRIQVEHTITEEITGIDIVAAQIQIAAGASLPQLGLFQDKITTRGFAIQCRITT 364
Query: 364 EDPSKNFQPDTGRIDVYRSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVR 423
EDP+KNFQPDTGRI+VYRSAGGNGVRLDGGNA+AG++ISPHYDSMLVKCSCSGSTYEIVR
Sbjct: 365 EDPAKNFQPDTGRIEVYRSAGGNGVRLDGGNAYAGTIISPHYDSMLVKCSCSGSTYEIVR 424
Query: 424 RKMLRALIEFRIRGVKTNIPFLLTLLTHPVFKSGEYWTTFIDDTPQLFEMVSSQNRAQKL 483
RKM+RALIEFRIRGVKTNIPFLLTLLT+PVF G YWTTFIDDTPQLF+MVSSQNRAQKL
Sbjct: 425 RKMIRALIEFRIRGVKTNIPFLLTLLTNPVFIEGTYWTTFIDDTPQLFQMVSSQNRAQKL 484
Query: 484 LHYLADLAVNGSSIKGQIGLPKLTTHPTIPHLHNEDGSLVDVS-AKPPAGWRDVLLDYGP 542
LHYLAD+AVNGSSIKGQIGLPKL ++P++PHLH+ G++++V+ + PP+GWR VLL+ GP
Sbjct: 485 LHYLADVAVNGSSIKGQIGLPKLKSNPSVPHLHDAQGNVINVTKSAPPSGWRQVLLEKGP 544
Query: 543 EEFAKQVRKFNGTLLMDTTWRDAHQSLLATRVRTYDLAAIAPTTAHAMSGAFALECWGGA 602
EFA+QVR+FNGTLLMDTTWRDAHQSLLATRVRT+DLA IAPTTAHA++G FALECWGGA
Sbjct: 545 AEFARQVRQFNGTLLMDTTWRDAHQSLLATRVRTHDLATIAPTTAHALAGRFALECWGGA 604
Query: 603 TFDVSMRFLHEDPWERLRTLRKLVPNIPFQMLLRGANGVAYSSLPDNAIDHFVKQAKDNG 662
TFDV+MRFLHEDPWERLR LR LVPNIPFQMLLRGANGVAYSSLPDNAIDHFVKQAKDNG
Sbjct: 605 TFDVAMRFLHEDPWERLRKLRSLVPNIPFQMLLRGANGVAYSSLPDNAIDHFVKQAKDNG 664
Query: 663 VDIFRVFDALNDLEQLXXXXXXXXXXXXXXXXTICYSGDMLAPGKKYNLDYYLDITEKIV 722
VDIFRVFDALNDLEQL T+C+SGDML PGKKYNLDYYL+I EKIV
Sbjct: 665 VDIFRVFDALNDLEQLKVGVDAVKKAGGVVEATVCFSGDMLQPGKKYNLDYYLEIAEKIV 724
Query: 723 NSGTHILGIKDMAGTLKPSAARLLIGSIRAKYPELPIHVHTHDSAGTGVASMAACALSGA 782
GTHILGIKDMAGT+KP+AA+LLIGS+RAKYP+LPIHVHTHDSAGT VASM ACAL+GA
Sbjct: 725 QMGTHILGIKDMAGTMKPAAAKLLIGSLRAKYPDLPIHVHTHDSAGTAVASMTACALAGA 784
Query: 783 DVVDVATNSMSGLTSQPSINALLAALDGEIDNNVNVGYVRELDAYWAEMRLLYSCFEADL 842
DVVDVA NSMSGLTSQPSINALLA+L+G ID +NV +VRELDAYWAEMRLLYSCFEADL
Sbjct: 785 DVVDVAINSMSGLTSQPSINALLASLEGNIDTGINVEHVRELDAYWAEMRLLYSCFEADL 844
Query: 843 KGPDPEVYVHEIPGGQLTNLLFQAQQLGLGEKWAETKRAYREANLLLGDLVKVTPTSKVV 902
KGPDPEVY HEIPGGQLTNLLFQAQQLGLGE+WAETKRAYREAN LLGD+VKVTPTSKVV
Sbjct: 845 KGPDPEVYQHEIPGGQLTNLLFQAQQLGLGEQWAETKRAYREANYLLGDIVKVTPTSKVV 904
Query: 903 GDLAQFMVSNKLTSDDVRRLASSLDFPDSVMDFFEGLIGQPYGGFPEPLRTDVLRNKRRK 962
GDLAQFMVSNKLTSDDVRRLA+SLDFPDSVMDFFEGLIGQPYGGFPEP R+DVLRNKRRK
Sbjct: 905 GDLAQFMVSNKLTSDDVRRLANSLDFPDSVMDFFEGLIGQPYGGFPEPFRSDVLRNKRRK 964
Query: 963 LTQRPGLELAPFELEKIKEDLSTRFSDIDECDVASYNMYPKVYEDFRKIKEKYGDLSVLP 1022
LT RPGLEL PF+LEKI+EDL RF D+DECDVASYNMYP+VYEDF+K++E YGDLSVLP
Sbjct: 965 LTCRPGLELEPFDLEKIREDLQNRFGDVDECDVASYNMYPRVYEDFQKMRETYGDLSVLP 1024
Query: 1023 TKNFLSPPVIGEEIVVTIEQGKTLIIKPQAIGDLNKETGIREVYFELNGELRKVSVADRS 1082
T++FLSP EEI V IEQGKTLIIK QA+GDLNK+TG REVYF+LNGE+RK+ VADRS
Sbjct: 1025 TRSFLSPLETDEEIEVVIEQGKTLIIKLQAVGDLNKKTGEREVYFDLNGEMRKIRVADRS 1084
Query: 1083 QKVESVSKPKADAHDPFQIGSPMAGVVVEVKVHKGSLIAKGQPVAVLSAMKMEMVISSPA 1142
QKVE+V+K KAD HDP IG+PMAGV+VEVKVHKGSLI KGQPVAVLSAMKMEM+ISSP+
Sbjct: 1085 QKVETVTKSKADMHDPLHIGAPMAGVIVEVKVHKGSLIKKGQPVAVLSAMKMEMIISSPS 1144
Query: 1143 DGQVKEVLVKDGENVDASDLLVVLEE 1168
DGQVKEV V DGENVD+SDLLV+LE+
Sbjct: 1145 DGQVKEVFVSDGENVDSSDLLVLLED 1170
>SPBC17G9.11c [C] KOG0369 Pyruvate carboxylase
Length = 1185
Score = 1483 bits (3839), Expect = 0.0
Identities = 740/1166 (63%), Positives = 902/1166 (76%), Gaps = 10/1166 (0%)
Query: 8 LRDNSNLMGEK-NKLLVANRGEIPIRIFRTAHELSMKTVAIYSHEDRLSMHRLKADEAYV 66
L+D S+L+GEK K+LVANR EI IR+FRTAHELSM TVAIYS+EDRLSMHR KADE+Y
Sbjct: 22 LQDRSSLLGEKFTKVLVANRSEIAIRVFRTAHELSMHTVAIYSYEDRLSMHRQKADESYP 81
Query: 67 IGEQGKYTPVGAYLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPA 126
IG+ G+Y+PVGAYLAIDEI++IAK G N +HPGYGFLSEN+EFA KV +G+ +VGP
Sbjct: 82 IGKVGQYSPVGAYLAIDEIVSIAKRTGANLVHPGYGFLSENAEFARKVNEAGMQFVGPSP 141
Query: 127 AVIDSVGDKVSARNLAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFXXXXXX 186
VIDS+GDK AR +A + VPVVPGTPGP+E EEA+AFV +YG PVIIKAA
Sbjct: 142 EVIDSLGDKTKARAIAIRCGVPVVPGTPGPVEHYEEAEAFVKEYGLPVIIKAAMGGGGRG 201
Query: 187 XXXXXXXDDISDAFQRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHLFER 246
D + ++F+RA+SEA+ +FG+GT FIERFLDKPKHIE+QL+AD GNV+HL ER
Sbjct: 202 MRVVRSADTLKESFERARSEALASFGDGTVFIERFLDKPKHIEIQLMADKAGNVIHLHER 261
Query: 247 DCSVQRRHQKVVEVAPAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVDNQNRHYFI 306
DCSVQRRHQKVVE+APAK L ++R A+ DA+K+AKE Y NAGTAEFL+D + RHYFI
Sbjct: 262 DCSVQRRHQKVVEIAPAKDLDPKIRQALYDDAIKIAKEVKYCNAGTAEFLLDQKGRHYFI 321
Query: 307 EINPRIQVEHTITEEITXXXXXXXXXXXXXXXTLEQLGLMQDKITTRGFAIQCRITTEDP 366
EINPRIQVEHTITEEIT TL ++GL QDKI+TRGFAIQCR+TTEDP
Sbjct: 322 EINPRIQVEHTITEEITGVDIVSAQLHVAAGFTLPEIGLTQDKISTRGFAIQCRVTTEDP 381
Query: 367 SKNFQPDTGRIDVYRSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKM 426
+ F PD G+I+VYRSAGGNGVRLDG N FAGSVI+PHYDSMLVKC+C +TYE RRKM
Sbjct: 382 NNGFAPDIGKIEVYRSAGGNGVRLDGANGFAGSVITPHYDSMLVKCTCHDATYEYTRRKM 441
Query: 427 LRALIEFRIRGVKTNIPFLLTLLTHPVFKSGEYWTTFIDDTPQLFEMVSSQNRAQKLLHY 486
+R+LIEFR+RGVKTNIPF+L LL H F G WTTFIDDTP+LF++ S+NRAQKLL Y
Sbjct: 442 IRSLIEFRVRGVKTNIPFVLRLLMHDTFIQGNCWTTFIDDTPELFQLYRSRNRAQKLLAY 501
Query: 487 LADLAVNGSSIKGQIGLPKLTTHPTIPHLHNEDGSLVDVSAKPPAGWRDVLLDYGPEEFA 546
L DLAVNGSSIKGQ G P L + +P L + G+ +DVS GWR +LLD GP FA
Sbjct: 502 LGDLAVNGSSIKGQNGEPALKSEIVMPVLLDSTGNQIDVSHPSEKGWRKLLLDNGPAAFA 561
Query: 547 KQVRKFNGTLLMDTTWRDAHQSLLATRVRTYDLAAIAPTTAHAMSGAFALECWGGATFDV 606
K VR L+MDTTWRDAHQSLLATRVRT DL IAP T+HA++ A++LE WGGATFDV
Sbjct: 562 KAVRNHKRGLIMDTTWRDAHQSLLATRVRTIDLVNIAPYTSHALASAYSLEMWGGATFDV 621
Query: 607 SMRFLHEDPWERLRTLRKLVPNIPFQMLLRGANGVAYSSLPDNAIDHFVKQAKDNGVDIF 666
SMRFLHE PW+RLR LRKLVPNIPFQMLLRGANG+ YSSLPDN I F +QAK NG+DIF
Sbjct: 622 SMRFLHECPWDRLRRLRKLVPNIPFQMLLRGANGLCYSSLPDNVIYFFCEQAKKNGIDIF 681
Query: 667 RVFDALNDLEQLXXXXXXXXXXXXXXXXTICYSGDMLAPGKKYNLDYYLDITEKIVNSGT 726
RVFDALND+ L T+CYSGDML P KKYNLDYY+++ +K+V G
Sbjct: 682 RVFDALNDVNNLSLGIDAAKRAGGVVEATMCYSGDMLNPKKKYNLDYYVNLVDKMVEMGI 741
Query: 727 HILGIKDMAGTLKPSAARLLIGSIRAKYPELPIHVHTHDSAGTGVASMAACALSGADVVD 786
HILGIKDMAG +KP AARLLI +IR K+PELPIHVHTHDSAGT VASMAA +GADVVD
Sbjct: 742 HILGIKDMAGVMKPKAARLLISAIREKHPELPIHVHTHDSAGTAVASMAAALEAGADVVD 801
Query: 787 VATNSMSGLTSQPSINALLAALDG-----EIDNNVNVGYVRELDAYWAEMRLLYSCFEAD 841
VAT+SMSGLTSQPS A+LA++DG E DNN +RE+D+YWA+MRLLYS FE++
Sbjct: 802 VATDSMSGLTSQPSFGAVLASVDGTDKQLEFDNN----QLREIDSYWAQMRLLYSPFESE 857
Query: 842 LKGPDPEVYVHEIPGGQLTNLLFQAQQLGLGEKWAETKRAYREANLLLGDLVKVTPTSKV 901
+KG D +VY HEIPGGQLTNL FQA LGLG +WAETK+AY EAN LLGD++KVTPTSKV
Sbjct: 858 IKGTDSDVYNHEIPGGQLTNLKFQATSLGLGTQWAETKKAYIEANKLLGDIIKVTPTSKV 917
Query: 902 VGDLAQFMVSNKLTSDDVRRLASSLDFPDSVMDFFEGLIGQPYGGFPEPLRTDVLRNKRR 961
VGDLAQFMV NKL+++DV A++LDFP SV+DFF+GL+GQPYGGFPEPLRT+VL+ +R+
Sbjct: 918 VGDLAQFMVQNKLSAEDVENRATTLDFPASVLDFFQGLMGQPYGGFPEPLRTNVLKGRRQ 977
Query: 962 KLTQRPGLELAPFELEKIKEDLSTRFSDIDECDVASYNMYPKVYEDFRKIKEKYGDLSVL 1021
LT RPG L + + I++ LS +F +CD+A+Y +P V+E++R+ ++YGDL+ +
Sbjct: 978 PLTDRPGKFLPAADFDAIRKLLSEKFGVSSDCDIAAYTQFPGVFEEYRQFVDRYGDLTTV 1037
Query: 1022 PTKNFLSPPVIGEEIVVTIEQGKTLIIKPQAIGDLNKETGIREVYFELNGELRKVSVADR 1081
PTK FLS P + EE+ V I+QGKTLI+K A+G LN TG REVYFELNGE R V+V D+
Sbjct: 1038 PTKFFLSRPEMNEEMHVEIDQGKTLIVKFVALGPLNPRTGQREVYFELNGENRHVTVEDK 1097
Query: 1082 SQKVESVSKPKADAHDPFQIGSPMAGVVVEVKVHKGSLIAKGQPVAVLSAMKMEMVISSP 1141
+E+V++P+AD +P + +PM+G +VE++V +G+ + KG +AVLSAMKME+VIS+P
Sbjct: 1098 KAAIETVTRPRADPGNPGHVAAPMSGTIVEIRVKEGAKVKKGDIIAVLSAMKMEIVISAP 1157
Query: 1142 ADGQVKEVLVKDGENVDASDLLVVLE 1167
G +K + V G++V+ DL VLE
Sbjct: 1158 HSGVLKSLAVVQGDSVNGGDLCAVLE 1183
>CE09072 [C] KOG0369 Pyruvate carboxylase
Length = 1175
Score = 1175 bits (3040), Expect = 0.0
Identities = 612/1156 (52%), Positives = 798/1156 (68%), Gaps = 17/1156 (1%)
Query: 17 EKNKLLVANRGEIPIRIFRTAHELSMKTVAIYSHEDRLSMHRLKADEAYVIGEQGKYTPV 76
E NK++VANRGEI IR+FR EL+ +VAIY+ +D+ SMHRLKADEAY++G+ PV
Sbjct: 31 EFNKVMVANRGEIAIRVFRALTELNKTSVAIYAEQDKNSMHRLKADEAYLVGKG--LPPV 88
Query: 77 GAYLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPAAVIDSVGDKV 136
AYL ID+II A H ++ IHPGYGFLSE S+FA +GI ++GP V+ +GDKV
Sbjct: 89 AAYLTIDQIIETALKHNIDAIHPGYGFLSERSDFAAACQNAGIVFIGPSPDVMARMGDKV 148
Query: 137 SARNLAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDI 196
+AR A +A V VVPGTPGPI T +EA F +YG P+I+KAA+ +++
Sbjct: 149 AARQAAIEAGVQVVPGTPGPITTADEAVEFAKQYGTPIILKAAYGGGGRGIRRVDKLEEV 208
Query: 197 SDAFQRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQK 256
+AF+R+ SEA AFG+G+ F+E+F+++P+HIEVQLL D++GN+VHL+ERDCSVQRRHQK
Sbjct: 209 EEAFRRSYSEAQAAFGDGSLFVEKFVERPRHIEVQLLGDHHGNIVHLYERDCSVQRRHQK 268
Query: 257 VVEVAPAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVDNQNRHYFIEINPRIQVEH 316
VVE+APA LPE VR+ IL DA++LA+ GY+NAGT EFLVD + +YFIE+N R+QVEH
Sbjct: 269 VVEIAPAPALPEGVREKILADALRLARHVGYQNAGTVEFLVDQKGNYYFIEVNARLQVEH 328
Query: 317 TITEEITXXXXXXXXXXXXXXXTLEQLGLMQDKITTRGFAIQCRITTEDPSKNFQPDTGR 376
T+TEEIT +L+ L L Q+ I T G AIQCR+TTEDP+K FQPD+GR
Sbjct: 329 TVTEEITGVDLVQAQIRIAEGKSLDDLKLSQETIQTTGSAIQCRVTTEDPAKGFQPDSGR 388
Query: 377 IDVYRSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIEFRIR 436
I+V+RS G G+RLD +AFAGSVISPHYDS++VK S + KM+RAL +FRIR
Sbjct: 389 IEVFRSGEGMGIRLDSASAFAGSVISPHYDSLMVKVIASARNHPNAAAKMIRALKKFRIR 448
Query: 437 GVKTNIPFLLTLLTHPVFKSGEYWTTFIDDTPQLFEMVSSQNRAQKLLHYLADLAVNGSS 496
GVKTNIPFLL +L P F T FID+ P+LF+ SQNRAQKLL+YL ++ VNG +
Sbjct: 449 GVKTNIPFLLNVLRQPSFLDASVDTYFIDEHPELFQFKPSQNRAQKLLNYLGEVKVNGPT 508
Query: 497 IKGQIGLPKLTTHPTIPHLHNEDGSLVDVSAKPPAGWRDVLLDYGPEEFAKQVRKFNGTL 556
L P IP+ + AKPP G RDVL+ GP EFAK+VR G +
Sbjct: 509 TPLATDLKPAVVSPPIPY--------IPAGAKPPTGLRDVLVQRGPTEFAKEVRSRPGCM 560
Query: 557 LMDTTWRDAHQSLLATRVRTYDLAAIAPTTAHAMSGAFALECWGGATFDVSMRFLHEDPW 616
+ DTT+RDAHQSLLATRVRTYD+AAI+P A + +G F+LE WGGATFDVSMRFLHE PW
Sbjct: 561 ITDTTFRDAHQSLLATRVRTYDMAAISPFVAQSFNGLFSLENWGGATFDVSMRFLHECPW 620
Query: 617 ERLRTLRKLVPNIPFQMLLRGANGVAYSSLPDNAIDHFVKQAKDNGVDIFRVFDALNDLE 676
ERL+TLRKL+PNIPFQ LLRGAN + YS+ PDN I F + A NG+D+FRVFD+LN L
Sbjct: 621 ERLQTLRKLIPNIPFQCLLRGANAMGYSNYPDNVIYKFCELAVKNGMDVFRVFDSLNYLP 680
Query: 677 QLXXXXXXXXXXXXXXXXTICYSGDMLAPGK-KYNLDYYLDITEKIVNSGTHILGIKDMA 735
L I Y+GD+ + KY+L YYL++ +++V + HIL IKDMA
Sbjct: 681 NLLVGMEAVGKAGGVVEAAIAYTGDVTDKSRDKYDLKYYLNLADQLVKAQAHILSIKDMA 740
Query: 736 GTLKPSAARLLIGSIRAKYPELPIHVHTHDSAGTGVASMAACALSGADVVDVATNSMSGL 795
G LKP AA+LLIG++R K+P++PIHVHTHD++G GVA+M CA +GADVVD A +SMSG+
Sbjct: 741 GVLKPEAAKLLIGALRDKFPDIPIHVHTHDTSGAGVAAMLECAKAGADVVDAAVDSMSGM 800
Query: 796 TSQPSINALLAALDG-EIDNNVNVGYVRELDAYWAEMRLLYSCFE--ADLKGPDPEVYVH 852
TSQPS+ A++A+L G + D +++ + + AYW R LY+ FE +K + +VY H
Sbjct: 801 TSQPSMGAIVASLQGTKHDTGLSLDDISKYSAYWESTRQLYAPFECATTMKSGNADVYKH 860
Query: 853 EIPGGQLTNLLFQAQQLGLGEKWAETKRAYREANLLLGDLVKVTPTSKVVGDLAQFMVSN 912
EIPGGQ TNL FQA LGLG ++ E KR YREANL+LGD++KVTP+SK+VGDLAQFMV N
Sbjct: 861 EIPGGQYTNLQFQAFSLGLGPQFDEVKRMYREANLVLGDIIKVTPSSKIVGDLAQFMVQN 920
Query: 913 KLTSDDVRRLASSLDFPDSVMDFFEGLIGQPYGGFPEPLRTDVLRNKRRKLTQRPGLELA 972
LT + + A L FP SV+DF +G +GQP GFPEPLRT VLR K K+ RPG
Sbjct: 921 NLTRETLVDRADDLSFPKSVVDFMQGNVGQPPYGFPEPLRTKVLRGK-PKVDGRPGENAK 979
Query: 973 PFELEKIKEDLSTRFS-DIDECDVASYNMYPKVYEDFRKIKEKYGDLSVLPTKNFLSPPV 1031
P +L+ +K +L + + E DV SY+M+P V+++F +++YG + LPT+ FL+
Sbjct: 980 PVDLDAVKVELEEKHGRTLSEEDVMSYSMFPTVFDEFETFRQQYGPVDKLPTRLFLTGLE 1039
Query: 1032 IGEEIVVTIEQGKTLIIKPQAIGDLNKETGIREVYFELNGELRKVSVADRSQKVESVSKP 1091
I EE+ V IE GKTL I+ A G LNK G REV+F+LNG++R + V D+ E V++P
Sbjct: 1040 IAEEVDVEIESGKTLAIQLLAEGKLNKR-GEREVFFDLNGQMRSIFVVDKEASKEIVTRP 1098
Query: 1092 KADAHDPFQIGSPMAGVVVEVKVHKGSLIAKGQPVAVLSAMKMEMVISSPADGQVKEVLV 1151
+A IG+PM G V+E+K+ +G + K QP+ VLSAMKMEMVI SP G VK +
Sbjct: 1099 RALPGVRGHIGAPMPGDVLELKIKEGDKVTKKQPLFVLSAMKMEMVIDSPIAGTVKAIHA 1158
Query: 1152 KDGENVDASDLLVVLE 1167
G A DL+V +E
Sbjct: 1159 PQGTKCSAGDLVVEVE 1174
>7303838 [C] KOG0369 Pyruvate carboxylase
Length = 1181
Score = 1160 bits (3002), Expect = 0.0
Identities = 596/1151 (51%), Positives = 791/1151 (67%), Gaps = 15/1151 (1%)
Query: 21 LLVANRGEIPIRIFRTAHELSMKTVAIYSHEDRLSMHRLKADEAYVIGEQGKYTPVGAYL 80
+LVANRGEI IR+FR EL +K+VA+YS +D++ MHR KADE+Y++G+ PV AYL
Sbjct: 42 VLVANRGEIAIRVFRACTELGIKSVAVYSEQDKMHMHRQKADESYIVGKG--LPPVEAYL 99
Query: 81 AIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPAAVIDSVGDKVSARN 140
I E+I + K + V+ +HPGYGFLSE S+FA+ V +G+ ++GP V+ +GDKV+AR
Sbjct: 100 NIPELIRVCKENDVDAVHPGYGFLSERSDFAQAVIDAGLRFIGPSPEVVQKMGDKVAARV 159
Query: 141 LAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISDAF 200
A +A VP+VPGT GP+ T EEA F K+G PVI KAA+ +D+ ++F
Sbjct: 160 AAIEAGVPIVPGTDGPVTTKEEALEFCKKHGLPVIFKAAYGGGGRGMRVVRKMEDVEESF 219
Query: 201 QRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKVVEV 260
QRA SEA AFGNG FIE+F+++P+HIEVQLL D GNVVHL+ERDCSVQRRHQKVVE+
Sbjct: 220 QRASSEAKAAFGNGAMFIEKFIERPRHIEVQLLGDKAGNVVHLYERDCSVQRRHQKVVEI 279
Query: 261 APAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHTITE 320
APA LP E+RD + AV+LA+ GY NAGT EFL D YFIE+N R+QVEHT+TE
Sbjct: 280 APAPRLPIEIRDKMTEAAVRLARHVGYENAGTVEFLCDESGNFYFIEVNARLQVEHTVTE 339
Query: 321 EITXXXXXXXXXXXXXXXTLEQLGLMQDKITTRGFAIQCRITTEDPSKNFQPDTGRIDVY 380
EIT TL +LG QDKI RG+AIQCR+TTEDP+ +FQP+TGR++V+
Sbjct: 340 EITGIDLVQSQIRVAEGMTLPELGYTQDKIVPRGYAIQCRVTTEDPANDFQPNTGRLEVF 399
Query: 381 RSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIEFRIRGVKT 440
RS G G+RLD +A+AG++ISP+YDS+LVK S + KM RAL EFRIRGVKT
Sbjct: 400 RSGEGMGIRLDSASAYAGAIISPYYDSLLVKVISHASDLQSSASKMNRALREFRIRGVKT 459
Query: 441 NIPFLLTLLTHPVFKSGEYWTTFIDDTPQLFEMVSSQNRAQKLLHYLADLAVNGSSIKGQ 500
NIPFLL +L + F G T FID+ PQLF+ S NRAQKLL+Y+ ++ VNG
Sbjct: 460 NIPFLLNVLENQKFLHGVLDTYFIDEHPQLFKFKPSLNRAQKLLNYMGEVLVNGPQTPLA 519
Query: 501 IGLPKLTTHPTIPHLHNEDGSLVDVSAKPPAGWRDVLLDYGPEEFAKQVRKFNGTLLMDT 560
L P +P V + +PP G R+VL+ GPE FAK+VR LLMDT
Sbjct: 520 TTLKPALVSPHVPE--------VPLVTEPPKGLREVLVCEGPEAFAKEVRNRKELLLMDT 571
Query: 561 TWRDAHQSLLATRVRTYDLAAIAPTTAHAMSGAFALECWGGATFDVSMRFLHEDPWERLR 620
T+RDAHQSLLATRVR++DL I+P H + ++LE WGGATFDV++RFLHE PWERL
Sbjct: 572 TFRDAHQSLLATRVRSHDLLKISPYVTHKFNNLYSLENWGGATFDVALRFLHECPWERLE 631
Query: 621 TLRKLVPNIPFQMLLRGANGVAYSSLPDNAIDHFVKQAKDNGVDIFRVFDALNDLEQLXX 680
+RK +PNIPFQMLLRGAN V Y+S PDN + F + A G+DIFRVFD+LN L L
Sbjct: 632 EMRKRIPNIPFQMLLRGANAVGYTSYPDNVVYKFCELAVQTGMDIFRVFDSLNYLPNLIL 691
Query: 681 XXXXXXXXXXXXXXTICYSGDMLAPGK-KYNLDYYLDITEKIVNSGTHILGIKDMAGTLK 739
I Y+GD+ P + KY+L YY ++ +++V +GTH+L IKDMAG LK
Sbjct: 692 GMEAAGKAGGVVEAAISYTGDVSDPKRTKYDLKYYTNLADELVKAGTHVLCIKDMAGLLK 751
Query: 740 PSAARLLIGSIRAKYPELPIHVHTHDSAGTGVASMAACALSGADVVDVATNSMSGLTSQP 799
P +ARLLI +IR K+P++PIH+HTHD++G GVASM ACA +GADVVDVA +SMSG+TSQP
Sbjct: 752 PESARLLITAIRDKHPDIPIHIHTHDTSGAGVASMLACANAGADVVDVAVDSMSGMTSQP 811
Query: 800 SINALLAALDG-EIDNNVNVGYVRELDAYWAEMRLLYSCFE--ADLKGPDPEVYVHEIPG 856
S+ A++A+L G +D N+++ V E AYW + R LY+ FE ++ + +VY++EIPG
Sbjct: 812 SMGAVVASLQGTPLDTNLDLRTVSEYSAYWEQTRTLYAPFECTTTMRSGNADVYLNEIPG 871
Query: 857 GQLTNLLFQAQQLGLGEKWAETKRAYREANLLLGDLVKVTPTSKVVGDLAQFMVSNKLTS 916
GQ TNL FQA LGLG+ + + K+AYREANLLLGD++KVTP+SKVVGDLAQFMV N LT+
Sbjct: 872 GQYTNLQFQAFSLGLGDFFEDVKKAYREANLLLGDIIKVTPSSKVVGDLAQFMVQNDLTA 931
Query: 917 DDVRRLASSLDFPDSVMDFFEGLIGQPYGGFPEPLRTDVLRNKRRKLTQRPGLELAPFEL 976
D V A L FP SV+++ +G IG P+GGFPEPLR+ VL++ R + RPG EL +
Sbjct: 932 DQVLERAEELSFPKSVVEYLQGSIGIPHGGFPEPLRSRVLKDMPR-IEGRPGAELKDLDF 990
Query: 977 EKIKEDLSTRFSDIDECDVASYNMYPKVYEDFRKIKEKYGDLSVLPTKNFLSPPVIGEEI 1036
+K+K++L + + DV S +YP+V DF +EKYG + L T+ FL+ P +GEE
Sbjct: 991 DKLKKELQESHTCVTNRDVMSAALYPQVTNDFLNFREKYGPVDKLDTRIFLTGPKVGEEF 1050
Query: 1037 VVTIEQGKTLIIKPQAIGDLNKETGIREVYFELNGELRKVSVADRSQKVESVSKPKADAH 1096
V +E+GKTL +K A+ K GIREV+FELNG+LR V + D+ E PKA+
Sbjct: 1051 DVPLERGKTLSVKALAVSADLKPNGIREVFFELNGQLRAVHILDKEAVKEIHVHPKANKS 1110
Query: 1097 DPFQIGSPMAGVVVEVKVHKGSLIAKGQPVAVLSAMKMEMVISSPADGQVKEVLVKDGEN 1156
+ ++G+PM G V++++V G + KGQP+ VLSAMKMEMV+ SP G VK++ + +G
Sbjct: 1111 NKSEVGAPMPGTVIDIRVKVGDKVEKGQPLVVLSAMKMEMVVQSPLAGVVKKLEIANGTK 1170
Query: 1157 VDASDLLVVLE 1167
++ DL++++E
Sbjct: 1171 LEGEDLIMIIE 1181
>Hs4505627 [C] KOG0369 Pyruvate carboxylase
Length = 1178
Score = 1137 bits (2940), Expect = 0.0
Identities = 588/1153 (50%), Positives = 779/1153 (66%), Gaps = 18/1153 (1%)
Query: 20 KLLVANRGEIPIRIFRTAHELSMKTVAIYSHEDRLSMHRLKADEAYVIGEQGKYTPVGAY 79
K++VANRGEI IR+FR EL ++TVAIYS +D MHR KADEAY+IG PV AY
Sbjct: 39 KVMVANRGEIAIRVFRACTELGIRTVAIYSEQDTGQMHRQKADEAYLIGRG--LAPVQAY 96
Query: 80 LAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPAAVIDSVGDKVSAR 139
L I +II +AK + V+ +HPGYGFLSE ++FA+ +G+ ++GP V+ +GDKV AR
Sbjct: 97 LHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEAR 156
Query: 140 NLAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISDA 199
+A A VPVVPGT PI ++ EA F + YGFP+I KAA+ +++ +
Sbjct: 157 AIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEEN 216
Query: 200 FQRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKVVE 259
+ RA SEA+ AFGNG F+E+F++KP+HIEVQ+L D YGN++HL+ERDCS+QRRHQKVVE
Sbjct: 217 YTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVE 276
Query: 260 VAPAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHTIT 319
+APA L ++R + +D+VKLAK+ GY NAGT EFLVD +HYFIE+N R+QVEHT+T
Sbjct: 277 IAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVT 336
Query: 320 EEITXXXXXXXXXXXXXXXTLEQLGLMQDKITTRGFAIQCRITTEDPSKNFQPDTGRIDV 379
EEIT +L LGL Q+ I G AIQCR+TTEDP+++FQPDTGRI+V
Sbjct: 337 EEITDVDLVHAQIHVSEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEV 396
Query: 380 YRSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIEFRIRGVK 439
+RS G G+RLD +AF G+VISPHYDS+LVK G + KM RAL EFR+RGVK
Sbjct: 397 FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVK 456
Query: 440 TNIPFLLTLLTHPVFKSGEYWTTFIDDTPQLFEMVSSQNRAQKLLHYLADLAVNGSSIKG 499
TNI FL +L + F +G T FID+ P+LF++ +QNRAQKLLHYL + VNG +
Sbjct: 457 TNIAFLQNVLNNQQFLAGTVDTQFIDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPI 516
Query: 500 QIGLPKLTTHPTIPHLHNEDGSLVDVSAKPPAGWRDVLLDYGPEEFAKQVRKFNGTLLMD 559
+ T P +P + PPAG+RD+LL GPE FA+ VR G LLMD
Sbjct: 517 PVKASPSPTDPVVPAV---------PIGPPPAGFRDILLREGPEGFARAVRNHPGLLLMD 567
Query: 560 TTWRDAHQSLLATRVRTYDLAAIAPTTAHAMSGAFALECWGGATFDVSMRFLHEDPWERL 619
TT+RDAHQSLLATRVRT+DL IAP AH S F++E WGGATFDV+MRFL+E PW RL
Sbjct: 568 TTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSKLFSMENWGGATFDVAMRFLYECPWRRL 627
Query: 620 RTLRKLVPNIPFQMLLRGANGVAYSSLPDNAIDHFVKQAKDNGVDIFRVFDALNDLEQLX 679
+ LR+L+PNIPFQMLLRGAN V Y++ PDN + F + AK+NG+D+FRVFD+LN L +
Sbjct: 628 QELRELIPNIPFQMLLRGANAVGYTNYPDNVVFKFCEVAKENGMDVFRVFDSLNYLPNML 687
Query: 680 XXXXXXXXXXXXXXXTICYSGDMLAPGK-KYNLDYYLDITEKIVNSGTHILGIKDMAGTL 738
I Y+GD+ P + KY+L YY+ + E++V +GTHIL IKDMAG L
Sbjct: 688 LGMEAAGSAGGVVEAAISYTGDVADPSRTKYSLQYYMGLAEELVRAGTHILCIKDMAGLL 747
Query: 739 KPSAARLLIGSIRAKYPELPIHVHTHDSAGTGVASMAACALSGADVVDVATNSMSGLTSQ 798
KP+A +L+ S+R ++P+LP+H+HTHD++G GVA+M ACA +GADVVDVA +SMSG+TSQ
Sbjct: 748 KPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGVAAMLACAQAGADVVDVAADSMSGMTSQ 807
Query: 799 PSINALLAALDG-EIDNNVNVGYVRELDAYWAEMRLLYSCFE--ADLKGPDPEVYVHEIP 855
PS+ AL+A G +D V + V + YW R LY+ F+ A +K + +VY +EIP
Sbjct: 808 PSMGALVACTRGTPLDTEVPMERVFDYSEYWEGARGLYAAFDCTATMKSGNSDVYENEIP 867
Query: 856 GGQLTNLLFQAQQLGLGEKWAETKRAYREANLLLGDLVKVTPTSKVVGDLAQFMVSNKLT 915
GGQ TNL FQA +GLG K+ E K+AY EAN +LGDL+KVTP+SK+VGDLAQFMV N L+
Sbjct: 868 GGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQMLGDLIKVTPSSKIVGDLAQFMVQNGLS 927
Query: 916 SDDVRRLASSLDFPDSVMDFFEGLIGQPYGGFPEPLRTDVLRNKRRKLTQRPGLELAPFE 975
+ A L FP SV++F +G IG P+GGFPEP R+ VL++ R + RPG L P +
Sbjct: 928 RAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFPEPFRSKVLKDLPR-VEGRPGASLPPLD 986
Query: 976 LEKIKEDLSTRF-SDIDECDVASYNMYPKVYEDFRKIKEKYGDLSVLPTKNFLSPPVIGE 1034
L+ ++++L R ++ DV S MYP V+ F+ +G L L T+ FL P I E
Sbjct: 987 LQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHFKDFTATFGPLDSLNTRLFLQGPKIAE 1046
Query: 1035 EIVVTIEQGKTLIIKPQAIGDLNKETGIREVYFELNGELRKVSVADRSQKVESVSKPKAD 1094
E V +E+GKTL IK A+ DLN+ G R+V+FELNG+LR + V D E PKA
Sbjct: 1047 EFEVELERGKTLHIKALAVSDLNR-AGQRQVFFELNGQLRSILVKDTQAMKEMHFHPKAL 1105
Query: 1095 AHDPFQIGSPMAGVVVEVKVHKGSLIAKGQPVAVLSAMKMEMVISSPADGQVKEVLVKDG 1154
QIG+PM G V+++KV G+ +AKGQP+ VLSAMKME V++SP +G V++V V
Sbjct: 1106 KDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVLSAMKMETVVTSPMEGTVRKVHVTKD 1165
Query: 1155 ENVDASDLLVVLE 1167
++ DL++ +E
Sbjct: 1166 MTLEGDDLILEIE 1178
>At5g35360 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 537
Score = 333 bits (855), Expect = 7e-91
Identities = 190/446 (42%), Positives = 257/446 (57%), Gaps = 7/446 (1%)
Query: 19 NKLLVANRGEIPIRIFRTAHELSMKTVAIYSHEDRLSMHRLKADEAYVIGEQGKYTPVGA 78
+K+LVANRGEI +R+ RTAHE+ + VA+YS D+ ++H ADEA IGE +
Sbjct: 75 DKILVANRGEIAVRVIRTAHEMGIPCVAVYSTIDKDALHVKLADEAVCIGEAPSNQ---S 131
Query: 79 YLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPAAVIDSVGDKVSA 138
YL I +++ A S G +HPGYGFLSEN+ F E GI ++GP I +GDK +A
Sbjct: 132 YLVIPNVLSAAISRGCTMLHPGYGFLSENALFVEMCRDHGINFIGPNPDSIRVMGDKATA 191
Query: 139 RNLAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISD 198
R + A VP VPG+ G +++ EEA ++ GFPV+IKA +
Sbjct: 192 RETMKNAGVPTVPGSDGLLQSTEEAVRVANEIGFPVMIKATAGGGGRGMRLAKEPGEFVK 251
Query: 199 AFQRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKVV 258
Q+AKSEA AFGN C++E+F+ P+HIE Q+LAD +GNVVH ERDCS+QRR+QK++
Sbjct: 252 LLQQAKSEAAAAFGNDGCYLEKFVQNPRHIEFQVLADKFGNVVHFGERDCSIQRRNQKLL 311
Query: 259 EVAPAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHTI 318
E AP+ L E+R A+ AV A GY GT EFL+D + YF+E+N RIQVEH +
Sbjct: 312 EEAPSPALTAELRKAMGDAAVAAAASIGYIGVGTVEFLLDERGSFYFMEMNTRIQVEHPV 371
Query: 319 TEEITXXXXXXXXXXXXXXXTLEQLGLMQDKITTRGFAIQCRITTEDPSKNFQPDTGRID 378
TE I E+L Q+ I RG +I+CRI EDP K F+P GRI
Sbjct: 372 TEMIYSVDLIEEQIRVAMG---EKLRYKQEDIVLRGHSIECRINAEDPFKGFRPGPGRIT 428
Query: 379 VYRSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIEFRIRGV 438
Y +GG VR+D + ++ V+ P YDS+L K T E +M RAL + I GV
Sbjct: 429 SYLPSGGPFVRMD-SHVYSDYVVPPSYDSLLGKLIVWAPTREKAIERMKRALNDTIITGV 487
Query: 439 KTNIPFLLTLLTHPVFKSGEYWTTFI 464
T I + +L FK+G+ T FI
Sbjct: 488 PTTINYHKLILDVEDFKNGKVDTAFI 513
>At1g03090 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 734
Score = 314 bits (804), Expect = 6e-85
Identities = 182/448 (40%), Positives = 254/448 (56%), Gaps = 9/448 (2%)
Query: 20 KLLVANRGEIPIRIFRTAHELSMKTVAIYSHEDRLSMHRLKADEAYVIGEQGKYTPVGAY 79
K+LVANRGEI RI RTA L ++TVA+YS DR S+H ADEA IG +Y
Sbjct: 40 KILVANRGEIACRIMRTAKRLGIQTVAVYSDADRDSLHVKSADEAVRIGPPSARL---SY 96
Query: 80 LAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPAAVIDSVGDKVSAR 139
L+ I+ A G IHPGYGFLSE+S+FA+ SG+T++GPPA+ I +GDK +++
Sbjct: 97 LSGVTIMEAAARTGAQAIHPGYGFLSESSDFAQLCEDSGLTFIGPPASAIRDMGDKSASK 156
Query: 140 NLAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISDA 199
+ A VP+VPG G + ++ ++ +K G+P+IIK D +D+
Sbjct: 157 RIMGAAGVPLVPGYHGHEQDIDHMKSEAEKIGYPIIIKPTHGGGGKGMRIVQSGKDFADS 216
Query: 200 FQRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKVVE 259
F A+ EA +FG T +E+++ +P+HIEVQ+ D +GNV+HL+ERDCSVQRRHQK++E
Sbjct: 217 FLGAQREAAASFGVNTILLEKYITRPRHIEVQIFGDKHGNVLHLYERDCSVQRRHQKIIE 276
Query: 260 VAPAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVDNQ-NRHYFIEINPRIQVEHTI 318
APA + E+ R + AV A+ GY NAGT EF+VD + ++ YF+E+N R+QVEH +
Sbjct: 277 EAPAPNISEKFRANLGQAAVSAARAVGYYNAGTVEFIVDTESDQFYFMEMNTRLQVEHPV 336
Query: 319 TEEITXXXXXXXXXXXXXXXTLEQLGLMQDKITTRGFAIQCRITTEDPSKNFQPDTGRID 378
TE I E L L Q ++ G A + RI E+ K F P TG ++
Sbjct: 337 TEMIVGQDLVEWQIRVANG---EPLPLSQSEVPMSGHAFEARIYAENVPKGFLPATGVLN 393
Query: 379 VYRS-AGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIEFRIRG 437
YR A VR++ G G +S HYD M+ K G K+ L F++ G
Sbjct: 394 HYRPVAVSPSVRVETG-VEQGDTVSMHYDPMIAKLVVWGGNRGEALVKLKDCLSNFQVAG 452
Query: 438 VKTNIPFLLTLLTHPVFKSGEYWTTFID 465
V TNI FL L +H F G T FI+
Sbjct: 453 VPTNINFLQKLASHKEFAVGNVETHFIE 480
Score = 63.5 bits (153), Expect = 2e-09
Identities = 30/88 (34%), Positives = 53/88 (60%)
Query: 1076 VSVADRSQKVESVSKPKADAHDPFQIGSPMAGVVVEVKVHKGSLIAKGQPVAVLSAMKME 1135
+ ++ + V+ + + +H P I +PMAG+VV+V V + + +GQP+ VL AMKME
Sbjct: 642 IEFSEDEEGVQHRTSSETSSHPPGTIVAPMAGLVVKVLVENEAKVDQGQPILVLEAMKME 701
Query: 1136 MVISSPADGQVKEVLVKDGENVDASDLL 1163
V+ +P+ G ++++ VK G+ V L
Sbjct: 702 HVVKAPSSGSIQDLKVKAGQQVSDGSAL 729
>7302098 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 684
Score = 313 bits (802), Expect = 1e-84
Identities = 179/450 (39%), Positives = 257/450 (56%), Gaps = 9/450 (2%)
Query: 19 NKLLVANRGEIPIRIFRTAHELSMKTVAIYSHEDRLSMHRLKADEAYVIGEQGKYTPVGA 78
+K+L++NRGEI R+ RTA +L ++TVA++S D SMH ADE+Y +GE +
Sbjct: 28 SKILISNRGEIACRVIRTARKLGVRTVAVFSDPDEKSMHTQLADESYRVGEAASSA---S 84
Query: 79 YLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPAAVIDSVGDKVSA 138
YL + I++IAK G IHPGYGFLSE+ EFAE GI ++GPP++ I +G K ++
Sbjct: 85 YLRGERILDIAKRSGAQAIHPGYGFLSESVEFAELCQREGIIFMGPPSSAIRDMGIKSTS 144
Query: 139 RNLAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISD 198
+ + A VP++ G G ++ E Q DK GFP++IKA DD
Sbjct: 145 KAIMAAAGVPIINGYHGDDQSDECLQREADKIGFPLMIKAVRGGGGKGMRIAEKPDDFLT 204
Query: 199 AFQRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKVV 258
A A++E+ +FG+ + +ER++ P+H+EVQ+ AD YG+ V+L+ERDCSVQRRHQK++
Sbjct: 205 ALNSARTESEKSFGDSSVLLERYVRSPRHVEVQVFADQYGDAVYLWERDCSVQRRHQKII 264
Query: 259 EVAPAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVDNQN-RHYFIEINPRIQVEHT 317
E APA L E++R + AV+ AK GY AGT EF++D ++ +F+E+N R+QVEH
Sbjct: 265 EEAPAPGLSEDLRRELGEAAVRAAKAVGYVGAGTVEFILDKEDLSFHFMEMNTRLQVEHP 324
Query: 318 ITEEITXXXXXXXXXXXXXXXTLEQLGLMQDKITTRGFAIQCRITTEDPSKNFQPDTGRI 377
ITE IT E L L Q +IT RG A + RI E+P F P G +
Sbjct: 325 ITEMITGTDLVEWQIRIAAG---EPLPLKQSEITRRGHAFEARIYAENPRGGFLPGAGPL 381
Query: 378 DVYRS-AGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIEFRIR 436
+ N VR++ G G +S HYD M+ K G ++ L E+ I
Sbjct: 382 RYLSTPQPSNNVRVETG-VREGDEVSVHYDPMIAKLVVWGENRTQALNSLVARLGEYHIS 440
Query: 437 GVKTNIPFLLTLLTHPVFKSGEYWTTFIDD 466
G+ TNI FL+ L +HP F+ T FID+
Sbjct: 441 GLDTNINFLIDLASHPEFQLANVHTGFIDE 470
>Hs13518228 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 725
Score = 312 bits (800), Expect = 2e-84
Identities = 176/446 (39%), Positives = 255/446 (56%), Gaps = 8/446 (1%)
Query: 20 KLLVANRGEIPIRIFRTAHELSMKTVAIYSHEDRLSMHRLKADEAYVIGEQGKYTPVGAY 79
K+L+ANRGEI R+ RTA +L ++TVA+YS DR SMH ADEAY IG +Y
Sbjct: 51 KVLIANRGEIACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQ---SY 107
Query: 80 LAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPAAVIDSVGDKVSAR 139
L++++II +AK+ IHPG GFLSEN EFAE GI ++GPP + I +G K +++
Sbjct: 108 LSMEKIIQVAKTSAAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSK 167
Query: 140 NLAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISDA 199
++ A VPVV G G ++ + + + G+PV+IKA + +
Sbjct: 168 SIMAAAGVPVVEGYHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQ 227
Query: 200 FQRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKVVE 259
+ A+ EA +F + IE+F+D P+H+EVQ+ D++GN V+LFERDCSVQRRHQK++E
Sbjct: 228 LESARREAKKSFNDDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIE 287
Query: 260 VAPAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHTIT 319
APA + EVR + AV+ AK Y AGT EF++D+++ F+E+N R+QVEH +T
Sbjct: 288 EAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVT 347
Query: 320 EEITXXXXXXXXXXXXXXXTLEQLGLMQDKITTRGFAIQCRITTEDPSKNFQPDTG-RID 378
E IT E++ L Q++IT +G A + RI EDPS NF P G +
Sbjct: 348 EMITGTDLVEWQLRIAAG---EKIPLSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVH 404
Query: 379 VYRSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIEFRIRGV 438
+ R++ G G +S HYD M+ K + + K+ +L ++ I G+
Sbjct: 405 LSTPRADPSTRIETG-VRQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGL 463
Query: 439 KTNIPFLLTLLTHPVFKSGEYWTTFI 464
TNI FLL L HP F++G T FI
Sbjct: 464 PTNIDFLLNLSGHPEFEAGNVHTDFI 489
>CE09857 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 688
Score = 309 bits (792), Expect = 1e-83
Identities = 179/464 (38%), Positives = 256/464 (54%), Gaps = 25/464 (5%)
Query: 20 KLLVANRGEIPIRIFRTAHELSMKTVAIYSHEDRLSMHRLKADEAYVIGEQGKYTPVGA- 78
++LVANRGEI IR+ TA ++ ++TVA++S DR S+ KAD+AY IG P+ A
Sbjct: 21 RVLVANRGEIAIRVQNTARKMGIETVAVFSDADRNSLFVKKADKAYHIGP-----PLAAE 75
Query: 79 -YLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPAAVIDSVGDKVS 137
YL +D+IIN A G IHPGYGFLSEN+ FAEK A +G+ ++GPPA I +G K
Sbjct: 76 SYLNMDKIINSALRSGAQAIHPGYGFLSENAGFAEKCAQAGLVFIGPPAQAIRDMGAKNV 135
Query: 138 ARNLAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDIS 197
++ + E A VPVV G G ++ + + G+PV++KA + +
Sbjct: 136 SKQIMEDAKVPVVKGFHGEDQSDANLKKKSAEIGYPVMLKAVYGGGGKGMRIAWNEAEFE 195
Query: 198 DAFQRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKV 257
+ A++EA +FGN +E+F++KP+H+EVQ+ D++GN VHL+ERDCSVQRRHQK+
Sbjct: 196 EKLASARNEAKKSFGNDEMLVEKFVEKPRHVEVQVFGDHHGNYVHLWERDCSVQRRHQKI 255
Query: 258 VEVAPAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHT 317
+E APA + + R + AV+ A GY AGT EF++D + YF+E+N R+QVEH
Sbjct: 256 IEEAPAPNMEHDTRVKLGESAVRAAAAVGYVGAGTVEFIMDPRGEFYFMEMNTRLQVEHP 315
Query: 318 ITEEIT--------------XXXXXXXXXXXXXXXTLEQLGLMQDKITTRGFAIQCRITT 363
++E IT E+L L Q +I G A +CR+
Sbjct: 316 VSEAITGIDFIMGDWKLSNNLISGTDLVEWQLRVAQGEKLPLKQSEIPLNGHAFECRVYA 375
Query: 364 EDPSKN-FQPDTGRIDVYRSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIV 422
ED K F P GR++ R+D G +G +S HYD M+ K G +
Sbjct: 376 EDTRKGAFMPTAGRLNYVDFP--EDARIDTG-VVSGDEVSIHYDPMIAKVVVWGQDRAVA 432
Query: 423 RRKMLRALIEFRIRGVKTNIPFLLTLLTHPVFKSGEYWTTFIDD 466
K+ AL RI G+ TNI F+ +L HP F +G +T FI D
Sbjct: 433 AAKLESALARTRISGLPTNIDFVRRVLAHPEFAAGNVYTDFIPD 476
>Hs4557833 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 703
Score = 305 bits (782), Expect = 2e-82
Identities = 180/451 (39%), Positives = 255/451 (55%), Gaps = 11/451 (2%)
Query: 19 NKLLVANRGEIPIRIFRTAHELSMKTVAIYSHEDRLSMHRLKADEAYVIGEQGKYTPVG- 77
+K+LVANRGEI R+ RT ++ +KTVAI+S D S+H ADEA +G P
Sbjct: 39 DKILVANRGEIACRVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGP----APTSK 94
Query: 78 AYLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPAAVIDSVGDKVS 137
+YL +D I+ K +HPGYGFLSEN EFA +AA + ++GP I ++GDK+
Sbjct: 95 SYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKIE 154
Query: 138 ARNLAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDIS 197
++ LA+KA V +PG G ++ EEA + G+PV+IKA+ ++
Sbjct: 155 SKLLAKKAEVNTIPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETR 214
Query: 198 DAFQRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKV 257
D F+ + EA ++FG+ IE+F+D P+HIE+Q+L D +GN + L ER+CS+QRR+QKV
Sbjct: 215 DGFRLSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKV 274
Query: 258 VEVAPAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHT 317
VE AP+ L E R A+ AV LA+ Y +AGT EFLVD++ YF+E+N R+QVEH
Sbjct: 275 VEEAPSIFLDAETRRAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHP 334
Query: 318 ITEEITXXXXXXXXXXXXXXXTLEQLGLMQDKITTRGFAIQCRITTEDPSKNF-QPDTGR 376
+TE IT L Q I G+A++CR+ EDP K+F P GR
Sbjct: 335 VTECITGLDLVQEMIRVAKGYPLRH---KQADIRINGWAVECRVYAEDPYKSFGLPSIGR 391
Query: 377 IDVYRS-AGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIEFRI 435
+ Y+ GVR+D G GS IS +YD M+ K GS ++M AL + I
Sbjct: 392 LSQYQEPLHLPGVRVDSG-IQPGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYVI 450
Query: 436 RGVKTNIPFLLTLLTHPVFKSGEYWTTFIDD 466
RGV NI L ++ + F G+ T F+ D
Sbjct: 451 RGVTHNIALLREVIINSRFVKGDISTKFLSD 481
Score = 57.4 bits (137), Expect = 1e-07
Identities = 38/113 (33%), Positives = 59/113 (51%), Gaps = 2/113 (1%)
Query: 1056 LNKETGIREVYFELNGELRKVSVADR-SQKVESVSKPKADAHDPFQIGSPMAGVVVEVKV 1114
L++E G + + G + KV++ R + ++ K + SPM GVVV V V
Sbjct: 592 LSREAG-GNMSIQFLGTVYKVNILTRLAAELNKFMLEKVTEDTSSVLRSPMPGVVVAVSV 650
Query: 1115 HKGSLIAKGQPVAVLSAMKMEMVISSPADGQVKEVLVKDGENVDASDLLVVLE 1167
G +A+GQ + V+ AMKM+ +++ G VK V + G+ V DLLV LE
Sbjct: 651 KPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHCQAGDTVGEGDLLVELE 703
>CE04451 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 724
Score = 300 bits (769), Expect = 7e-81
Identities = 172/469 (36%), Positives = 262/469 (55%), Gaps = 10/469 (2%)
Query: 19 NKLLVANRGEIPIRIFRTAHELSMKTVAIYSHEDRLSMHRLKADEAYVIGEQGKYTPVGA 78
+K+L+ANRGEI R+ +TA + +KTVA++S D S+H ADEA +GE +
Sbjct: 50 DKILIANRGEIACRVIKTARAMGIKTVAVHSDVDSNSLHVKMADEAVCVGEA---PTAKS 106
Query: 79 YLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPAAVIDSVGDKVSA 138
YL D I+ + G +HPGYGFLSEN++FA ++ +G ++GP + I +GDK+ +
Sbjct: 107 YLRADRILQAVEDTGAQAVHPGYGFLSENTKFAAELEKAGAKFIGPNSKAILDMGDKIHS 166
Query: 139 RNLAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISD 198
+ +A A V ++PG G I + G+PV+IKA+ +
Sbjct: 167 KKIATAARVSMIPGYDGEIADEDMCVKVSRDIGYPVMIKASAGGGGKGMRVAWNDKQARE 226
Query: 199 AFQRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKVV 258
++ +K EA ++FG+ +E+F+D P+HIE+Q+L D +GN + L ER+CS+QRR+QKV+
Sbjct: 227 GYRLSKQEAASSFGDDRMLVEKFIDNPRHIEMQVLCDKHGNALWLNERECSIQRRNQKVI 286
Query: 259 EVAPAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHTI 318
E AP+ +P E+R + AV+LAK GY +AGT EFLVD+Q YF+E+N R+QVEH I
Sbjct: 287 EEAPSSFVPPEMRRKMGEQAVQLAKAVGYDSAGTVEFLVDSQRNFYFLEMNTRLQVEHPI 346
Query: 319 TEEITXXXXXXXXXXXXXXXTLEQLGLMQDKITTRGFAIQCRITTEDPSKNF-QPDTGRI 377
TE IT L + Q+++ G+A + R+ EDP K F P GR+
Sbjct: 347 TECITGIDIVQQMLRVSYG---HPLPITQEQVPLNGWAFESRVYAEDPYKGFGLPSVGRL 403
Query: 378 DVY-RSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIEFRIR 436
Y +GVR D G GS IS +YD ++ K G E +M AL + IR
Sbjct: 404 SRYVEPKHVDGVRCDSG-IREGSEISIYYDPLICKLVTHGDNREQALNRMQEALDNYVIR 462
Query: 437 GVKTNIPFLLTLLTHPVFKSGEYWTTFIDDT-PQLFEMVSSQNRAQKLL 484
GV NIP L ++ F++G+ T ++ + P+ F+ S + Q ++
Sbjct: 463 GVTHNIPLLRDIVQEKRFRTGDITTKYLPEVYPEGFQGTSLSPKEQDVV 511
Score = 54.3 bits (129), Expect = 1e-06
Identities = 31/88 (35%), Positives = 48/88 (54%)
Query: 1080 DRSQKVESVSKPKADAHDPFQIGSPMAGVVVEVKVHKGSLIAKGQPVAVLSAMKMEMVIS 1139
+++ K K KA + SPM G + V V G ++++GQ + V+ AMKM+ +
Sbjct: 637 EQAVKYLQYMKEKAKVDLSTVVLSPMPGAIKNVNVKPGDMVSEGQELVVMEAMKMQNSLH 696
Query: 1140 SPADGQVKEVLVKDGENVDASDLLVVLE 1167
+ G+VK V VK G VD ++LV LE
Sbjct: 697 AGKTGRVKAVNVKVGATVDEGEVLVELE 724
>YBR208c_2 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 1200
Score = 267 bits (683), Expect = 6e-71
Identities = 160/457 (35%), Positives = 243/457 (53%), Gaps = 33/457 (7%)
Query: 21 LLVANRGEIPIRIFRTAHELSMKTVAIYSHEDRLSMHRLKADEAYVIGEQGKYTPVGAYL 80
+L+ANRGEI +RI +T +L +++VA+YS D+ S H AD + + T YL
Sbjct: 1 VLIANRGEIAVRIIKTLKKLGIRSVAVYSDPDKYSQHVTDADVSVPLHGT---TAAQTYL 57
Query: 81 AIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPAAVIDSVGDKVSARN 140
+++II+ AK I PGYGFLSEN++F++ ++GIT+VGP +I +G K SAR
Sbjct: 58 DMNKIIDAAKQTNAQAIIPGYGFLSENADFSDACTSAGITFVGPSGDIIRGLGLKHSARQ 117
Query: 141 LAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISDAF 200
+A+KA VP+VPG+ I +VEEA+ + +PV++K+ +DI F
Sbjct: 118 IAQKAGVPLVPGSL-LITSVEEAKKVAAELEYPVMVKSTAGGGGIGLQKVDSEEDIEHIF 176
Query: 201 QRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKVVEV 260
+ K + T FG+ F+ERF++ +H+EVQL+ D +G + L ERDCS+QRR+QKV+E
Sbjct: 177 ETVKHQGETFFGDAGVFLERFIENARHVEVQLMGDGFGKAIALGERDCSLQRRNQKVIEE 236
Query: 261 APAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVD-NQNRHYFIEINPRIQVEHTIT 319
PA LPE+ R A+ A L Y+ AGT EF+ D ++ YF+E+N R+QVEH IT
Sbjct: 237 TPAPNLPEKTRLALRKAAESLGSLLNYKCAGTVEFIYDEKKDEFYFLEVNTRLQVEHPIT 296
Query: 320 EEITXXXXXXXXXXXXXXXTLEQLGLMQDKITTRGFAIQCRITTEDPSKNFQPDTG---- 375
E +T + K+ G +++ R+ E+P KNF+P G
Sbjct: 297 EMVTGLDLVEWMIRIAANDAPD---FDSTKVEVNGVSMEARLYAENPLKNFRPSPGLLVD 353
Query: 376 -------RIDVYRSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLR 428
R+D + G N ISP YD L K G + K+ +
Sbjct: 354 VKFPDWARVDTWVKKGTN--------------ISPEYDPTLAKIIVHGKDRDDAISKLNQ 399
Query: 429 ALIEFRIRGVKTNIPFLLTLLTHPVFKSGEYWTTFID 465
AL E ++ G TNI +L +++T F + T ++
Sbjct: 400 ALEETKVYGCITNIDYLKSIITSDFFAKAKVSTNILN 436
>7304119 [I] KOG0368 Acetyl-CoA carboxylase
Length = 2348
Score = 199 bits (507), Expect = 2e-50
Identities = 150/509 (29%), Positives = 236/509 (45%), Gaps = 80/509 (15%)
Query: 19 NKLLVANRGEIPIRIFRTA---------HELSMKTVAIYSHEDRLSMHRLKADEAYVIGE 69
NK+L+AN G ++ R+ +E +++ V + + ED LKA+ Y I
Sbjct: 127 NKVLIANNGIAAVKCMRSIRRWAYEMFKNERAIRFVVMVTPED------LKANAEY-IKM 179
Query: 70 QGKYTPVGA------YLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVG 123
Y PV Y ++ I++IA V + G+G SEN + E + G+ ++G
Sbjct: 180 ADHYVPVPGGSNNNNYANVELIVDIALRTQVQAVWAGWGHASENPKLPELLHKEGLVFLG 239
Query: 124 PPAAVIDSVGDKVSARNLAEKANVPVVPGTP---------------------GPIETVEE 162
PP + ++GDKV++ +A+ A +P +P + G + VE+
Sbjct: 240 PPERAMWALGDKVASSIVAQTAEIPTLPWSGSDLKAQYSGKKIKISSELFARGCVTNVEQ 299
Query: 163 AQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISDAFQRAKSEAITAFGNGTCFIERFL 222
A V+K GFPV+IKA+ ++ F++ ++E F+ +
Sbjct: 300 GLAAVNKIGFPVMIKASEGGGGKGIRRVDTTEEFPGLFRQVQAEV----PGSPIFVMKLA 355
Query: 223 DKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKVVEVAPAKTLPEEVRDAILTDAVKLA 282
+H+EVQLLAD YGN + LF RDCS+QRRHQK++E APA EV + + AV+LA
Sbjct: 356 RGARHLEVQLLADQYGNAISLFGRDCSIQRRHQKIIEEAPAIVAQPEVFEDMEKAAVRLA 415
Query: 283 KEAGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHTITEEITXXXXXXXXXXXXXXXTLEQ 342
K GY +AGT E+L D + R++F+E+NPR+QVEH TE + L +
Sbjct: 416 KMVGYVSAGTVEYLYDPEGRYFFLELNPRLQVEHPCTEMVADVNLPAAQLQIGMGIPLYR 475
Query: 343 LGLMQ-------------------DKITTRGFAIQCRITTEDPSKNFQPDTGRIDV--YR 381
L ++ +K G I RIT+E+P + F+P +G + +R
Sbjct: 476 LKDIRLLYGESPWGSSVIDFENPPNKPRPSGHVIAARITSENPDEGFKPSSGTVQELNFR 535
Query: 382 SA----GGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIEFRIRG 437
S+ G V GG + DS C G + R ++ AL E IRG
Sbjct: 536 SSKNVWGYFSVAASGG-------LHEFADSQFGHCFSWGENRQQARENLVIALKELSIRG 588
Query: 438 -VKTNIPFLLTLLTHPVFKSGEYWTTFID 465
+T + +L+TLL F T ++D
Sbjct: 589 DFRTTVEYLITLLETNRFLDNSIDTAWLD 617
>SPAC56E4.04c [I] KOG0368 Acetyl-CoA carboxylase
Length = 2280
Score = 193 bits (490), Expect = 2e-48
Identities = 147/510 (28%), Positives = 237/510 (45%), Gaps = 73/510 (14%)
Query: 21 LLVANRGEIPIRIFRTAHELSMKTVAIYSHEDRLSM------HRLKADEAYV-IGEQGKY 73
+L+AN G ++ R+ + + +T +++E + LK + Y+ + +Q
Sbjct: 72 ILIANNGIAAVKEIRSIRKWAYET---FNNERAIKFTVMATPDDLKVNADYIRMADQYVE 128
Query: 74 TPVGA----YLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASG--ITWVGPPAA 127
P G+ Y ++ I++IA+ V+ + G+G SEN + E ++AS I ++GPP +
Sbjct: 129 VPGGSNNNNYANVELIVDIAERMNVHAVWAGWGHASENPKLPEMLSASSKKIVFIGPPGS 188
Query: 128 VIDSVGDKVSARNLAEKANVPVVPGTPGPIETV------------------------EEA 163
+ S+GDK+S+ +A+ A VP + + ++ V EE
Sbjct: 189 AMRSLGDKISSTIVAQSARVPCMSWSGNELDQVRIDEETNIVTVDDDVYQKACIRSAEEG 248
Query: 164 QAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISDAFQRAKSEAITAFGNGTCFIERFLD 223
A +K G+PV+IKA+ + + AFQ+ E F+ +
Sbjct: 249 IAVAEKIGYPVMIKASEGGGGKGIRQVTSTEKFAQAFQQVLDE----LPGSPVFVMKLAG 304
Query: 224 KPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKVVEVAPAKTLPEEVRDAILTDAVKLAK 283
+ +H+EVQ+LAD YGN + LF RDCSVQRRHQK++E AP P + AV+L +
Sbjct: 305 QARHLEVQILADQYGNNISLFGRDCSVQRRHQKIIEEAPVTIAPAATFHEMERAAVRLGE 364
Query: 284 EAGYRNAGTAEFLVDNQN-RHYFIEINPRIQVEHTITEEITXXXXXXXXXXXXXXXTLEQ 342
GY +AGT E+L + +N R YF+E+NPR+QVEH TE ++ L +
Sbjct: 365 LVGYASAGTIEYLYEPENDRFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQVAMGLPLSR 424
Query: 343 L-------GLMQD---------------KI----TTRGFAIQCRITTEDPSKNFQPDTGR 376
+ GL +D K+ T +G + CRIT+EDP + F+P +G
Sbjct: 425 IPHIRELYGLPRDGDSEIDFFFQNPESFKVQKVPTPKGHCVACRITSEDPGEGFKPSSGM 484
Query: 377 IDVYRSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIEFRIR 436
I + V AG I DS + E R+ M+ AL E IR
Sbjct: 485 IKDLNFRSSSNVWGYFSVGTAGG-IHEFADSQFGHIFSFAESRESSRKSMVVALKELSIR 543
Query: 437 G-VKTNIPFLLTLLTHPVFKSGEYWTTFID 465
G +T + +L+ LL F E+ T ++D
Sbjct: 544 GDFRTTVEYLVRLLETKEFSENEFTTGWLD 573
>YMR207c [I] KOG0368 Acetyl-CoA carboxylase
Length = 2123
Score = 187 bits (474), Expect = 1e-46
Identities = 141/487 (28%), Positives = 227/487 (45%), Gaps = 62/487 (12%)
Query: 59 LKADEAYV-IGEQGKYTPVGA----YLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEK 113
L A+ Y+ + +Q P G Y ID I+++A+ V+ + G+G SEN E
Sbjct: 29 LHANSEYIRMADQYVQVPGGTNNNNYANIDLILDVAEQTDVDAVWAGWGHASENPCLPEL 88
Query: 114 VAASG--ITWVGPPAAVIDSVGDKVSARNLAEKANVPVVPGTPGPIETV----------- 160
+A+S I ++GPP + S+GDK+S+ +A+ A +P +P + I+T+
Sbjct: 89 LASSQRKILFIGPPGRAMRSLGDKISSTIVAQSAKIPCIPWSGSHIDTIHIDNKTNFVSV 148
Query: 161 -------------EEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISDAFQRAKSEA 207
E+A GFPV+IKA+ DD +++A +E
Sbjct: 149 PDDVYVRGCCSSPEDALEKAKLIGFPVMIKASEGGGGKGIRRVDNEDDFIALYRQAVNET 208
Query: 208 ITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKVVEVAPAKTLP 267
F+ + + +H+EVQLLAD YG + LF RDCS+QRRHQK++E AP
Sbjct: 209 ----PGSPMFVMKVVTDARHLEVQLLADQYGTNITLFGRDCSIQRRHQKIIEEAPVTITK 264
Query: 268 EEVRDAILTDAVKLAKEAGYRNAGTAEFLVD-NQNRHYFIEINPRIQVEHTITEEITXXX 326
E + A++L + GY +AGT E+L ++ YF+E+NPR+QVEH TE I+
Sbjct: 265 PETFQRMERAAIRLGELVGYVSAGTVEYLYSPKDDKFYFLELNPRLQVEHPTTEMISGVN 324
Query: 327 XXXXXXXXXXXXTLEQLGLMQ------------------DKITTRGFAIQCRITTEDPSK 368
+ + ++ + + +G I CRIT+EDP++
Sbjct: 325 LPATQLQIAMGIPMHMISDIRKLYGLDPTGTSYIDFKNLKRPSPKGHCISCRITSEDPNE 384
Query: 369 NFQPDTGRIDV--YRSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKM 426
F+P TG+I +RS+ GN I DS G+ + ++ M
Sbjct: 385 GFKPSTGKIHELNFRSSSNVWGYFSVGN---NGAIHSFSDSQFGHIFAVGNDRQDAKQNM 441
Query: 427 LRALIEFRIRG-VKTNIPFLLTLLTHPVFKSGEYWTTFIDDTPQLFEMVSSQNRAQKLLH 485
+ AL +F IRG KT I +L+ LL F+S T ++DD + + +SS ++ L
Sbjct: 442 VLALKDFSIRGEFKTPIEYLIELLETRDFESNNISTGWLDDL--ILKNLSSDSKLDPTLA 499
Query: 486 YLADLAV 492
+ A+
Sbjct: 500 IICGAAM 506
>Hs4826637 [I] KOG0368 Acetyl-CoA carboxylase
Length = 2346
Score = 186 bits (471), Expect = 2e-46
Identities = 142/506 (28%), Positives = 227/506 (44%), Gaps = 71/506 (14%)
Query: 20 KLLVANRGEIPIRIFRTA---------HELSMKTVAIYSHEDRLSMHRLKADEAYV-IGE 69
K+L+AN G ++ R+ +E +++ V + + ED LKA+ Y+ + +
Sbjct: 120 KVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPED------LKANAEYIKMAD 173
Query: 70 QGKYTPVGA----YLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPP 125
P GA Y ++ I++IAK V + G+G SEN + E + +GI ++GPP
Sbjct: 174 HYVPVPGGANNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPP 233
Query: 126 AAVIDSVGDKVSARNLAEKANVPVVPGT--------------------------PGPIET 159
+ ++GDK+++ +A+ A +P +P + G ++
Sbjct: 234 NQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKD 293
Query: 160 VEEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISDAFQRAKSEAITAFGNGTCFIE 219
V++ +K G+PV+IKA+ DD + F++ ++E F+
Sbjct: 294 VDDGLKAAEKVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEV----PGSPIFVM 349
Query: 220 RFLDKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKVVEVAPAKTLPEEVRDAILTDAV 279
R + +H+EVQ+LAD YGN + LF RDCSVQRRHQK++E APA V + + AV
Sbjct: 350 RLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAV 409
Query: 280 KLAKEAGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHTITEEITXXXXXXXXXXXXXXXT 339
KLAK GY +AGT E+L YF+E+NPR+QVE TE +
Sbjct: 410 KLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEQPCTEMVADVNLPAAQLQIAMGIP 469
Query: 340 LEQLGLMQDKI-------------------TTRGFAIQCRITTEDPSKNFQPDTGRIDVY 380
L ++ ++ RG I RIT+E+P + F+P +G +
Sbjct: 470 LYRIKDIRMMYGVSPWGDSPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQEL 529
Query: 381 RSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIEFRIRG-VK 439
V A AG + S C G E M+ AL E IRG +
Sbjct: 530 NFRSNKNVWGYFSVAAAGG-LHEFAGSQFGHCFSWGENREEAISNMVVALKELSIRGDFR 588
Query: 440 TNIPFLLTLLTHPVFKSGEYWTTFID 465
T + +L+ LL F+ T ++D
Sbjct: 589 TTVEYLIKLLETESFQMNRIDTGWLD 614
>YNR016c [I] KOG0368 Acetyl-CoA carboxylase
Length = 2233
Score = 181 bits (460), Expect = 5e-45
Identities = 145/518 (27%), Positives = 231/518 (43%), Gaps = 83/518 (16%)
Query: 19 NKLLVANRGEIPIRIFRTAHELSMKT---------VAIYSHEDRLSMHRLKADEAYV-IG 68
+K+L+AN G ++ R+ + + +T VA+ + ED L+A+ Y+ +
Sbjct: 60 SKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPED------LEANAEYIRMA 113
Query: 69 EQGKYTPVGA----YLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASG--ITWV 122
+Q P G Y +D I++IA+ V+ + G+G SEN EK++ S + ++
Sbjct: 114 DQYIEVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIFI 173
Query: 123 GPPAAVIDSVGDKVSARNLAEKANVPVVPGTPGPIETV---------------------- 160
GPP + S+GDK+S+ +A+ A VP +P + ++TV
Sbjct: 174 GPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTGLVSVDDDIYQKGCCT 233
Query: 161 --EEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISDAFQRAKSEAITAFGNGTCFI 218
E+ + GFPV+IKA+ +D + +A +E FI
Sbjct: 234 SPEDGLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYHQAANE----IPGSPIFI 289
Query: 219 ERFLDKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKVVEVAPAKTLPEEVRDAILTDA 278
+ + +H+EVQLLAD YG + LF RDCSVQRRHQK++E AP E + A
Sbjct: 290 MKLAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIAKAETFHEMEKAA 349
Query: 279 VKLAKEAGYRNAGTAEFLVDNQN-RHYFIEINPRIQVEHTITEEITXXXXXXXXXXXXXX 337
V+L K GY +AGT E+L + + + YF+E+NPR+QVEH TE ++
Sbjct: 350 VRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMG 409
Query: 338 XTLEQLG--------------------------LMQDKITTRGFAIQCRITTEDPSKNFQ 371
+ ++ Q + +G CRIT+EDP+ F+
Sbjct: 410 IPMHRISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITSEDPNDGFK 469
Query: 372 PDTGRIDV--YRSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLRA 429
P G + +RS+ GN I DS G + R+ M+ A
Sbjct: 470 PSGGTLHELNFRSSSNVWGYFSVGN---NGNIHSFSDSQFGHIFAFGENRQASRKHMVVA 526
Query: 430 LIEFRIRG-VKTNIPFLLTLLTHPVFKSGEYWTTFIDD 466
L E IRG +T + +L+ LL F+ T ++DD
Sbjct: 527 LKELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLDD 564
>At1g36160 [I] KOG0368 Acetyl-CoA carboxylase
Length = 2247
Score = 177 bits (449), Expect = 9e-44
Identities = 133/509 (26%), Positives = 224/509 (43%), Gaps = 69/509 (13%)
Query: 19 NKLLVANRGEIPIRIFRTAHELSMKT---------VAIYSHED-RLSMHRLKADEAYVIG 68
+ +L+AN G ++ R+ + +T V + + ED R++ ++ + +V
Sbjct: 38 HSILIANNGMAAVKFIRSVRTWAYETFGTEKAILLVGMATPEDMRINAEHIRIADQFVEV 97
Query: 69 EQGKYTPVGAYLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPAAV 128
G T Y + I+ +A+ V+ + PG+G SEN E + + A GI ++GPPA+
Sbjct: 98 PGG--TNNNNYANVQLIVEMAEVTRVDAVWPGWGHASENPELPDALDAKGIIFLGPPASS 155
Query: 129 IDSVGDKVSARNLAEKANVPVVPGTPGPIE---------------------TVEEAQAFV 167
+ ++GDK+ + +A+ A+VP +P + ++ T EEA A
Sbjct: 156 MAALGDKIGSSLIAQAADVPTLPWSGSHVKIPPNSNLVTIPEEIYRQACVYTTEEAIASC 215
Query: 168 DKYGFPVIIKAAFXXXXXXXXXXXXXDDISDAFQRAKSEAITAFGNGTCFIERFLDKPKH 227
G+P +IKA++ D++ F++ + E FI + + +H
Sbjct: 216 QVVGYPAMIKASWGGGGKGIRKVHNDDEVRALFKQVQGEV----PGSPIFIMKVASQSRH 271
Query: 228 IEVQLLADNYGNVVHLFERDCSVQRRHQKVVEVAPAKTLPEEVRDAILTDAVKLAKEAGY 287
+EVQLL D +GNV L RDCSVQRRHQK++E P P E + A +LAK Y
Sbjct: 272 LEVQLLCDKHGNVSALHSRDCSVQRRHQKIIEEGPITVAPPETVKKLEQAARRLAKSVNY 331
Query: 288 RNAGTAEFLVD-NQNRHYFIEINPRIQVEHTITEEITXXXXXXXXXXXXXXXTLEQLGLM 346
A T E+L + +YF+E+NPR+QVEH +TE I L Q+ +
Sbjct: 332 VGAATVEYLYSMDTGEYYFLELNPRLQVEHPVTEWIAEINLPAAQVAVGMGIPLWQIPEI 391
Query: 347 Q-----------------------------DKITTRGFAIQCRITTEDPSKNFQPDTGRI 377
+ I +G + R+T+EDP F+P +GR+
Sbjct: 392 RRFYGIEHGGGYDSWRKTSVVAFPFDFDKAQSIRPKGHCVAVRVTSEDPDDGFKPTSGRV 451
Query: 378 DVYRSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIEFRIRG 437
V + +G I DS G + + M+ L E +IRG
Sbjct: 452 QELSFKSKPNV-WAYFSVKSGGGIHEFSDSQFGHVFAFGESRALAIANMVLGLKEIQIRG 510
Query: 438 -VKTNIPFLLTLLTHPVFKSGEYWTTFID 465
++TN+ + + LL ++ + T ++D
Sbjct: 511 EIRTNVDYTIDLLHASDYRDNKIHTGWLD 539
>At1g36180 [I] KOG0368 Acetyl-CoA carboxylase
Length = 2359
Score = 177 bits (448), Expect = 1e-43
Identities = 134/521 (25%), Positives = 228/521 (43%), Gaps = 82/521 (15%)
Query: 19 NKLLVANRGEIPIRIFRTAH---------ELSMKTVAIYSHED-RLSMHRLKADEAYVIG 68
+ +LVA G ++ R+ E ++K VA+ + ED R++ ++ + +V
Sbjct: 140 HSILVATNGMAAVKFIRSVRTWAYETFGSEKAVKLVAMATPEDMRINAEHIRIADQFVEV 199
Query: 69 EQGKYTPVGAYLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPAAV 128
G T Y + I+ +A+ V+ + PG+G SEN E + + GI ++GPPA
Sbjct: 200 PGG--TNNNNYANVQLIVEMAEVTRVDAVWPGWGHASENPELPDALKEKGIIFLGPPADS 257
Query: 129 IDSVGDKVSARNLAEKANVPVVPGT-------PGP--------------IETVEEAQAFV 167
+ ++GDK+ + +A+ A+VP +P + PG + T EEA A
Sbjct: 258 MIALGDKIGSSLIAQAADVPTLPWSGSHVKIPPGRSLVTVPEEIYKKACVYTTEEAIASC 317
Query: 168 DKYGFPVIIKAAFXXXXXXXXXXXXXDDISDAFQRAKSEAITAFGNGTCFIERFLDKPKH 227
G+P +IKA++ D++ F++ + E FI + + +H
Sbjct: 318 QVVGYPAMIKASWGGGGKGIRKVHNDDEVRALFKQVQGEV----PGSPIFIMKVASQSRH 373
Query: 228 IEVQLLADNYGNVVHLFERDCSVQRRHQKVVEVAPAKTLPEEVRDAILTDAVKLAKEAGY 287
+E QLL D YGNV L RDCSVQRRHQK++E P P+E + A +LAK Y
Sbjct: 374 LEAQLLCDQYGNVAALHSRDCSVQRRHQKIIEEGPITVAPQETIKKLEQAARRLAKSVNY 433
Query: 288 RNAGTAEFLVD-NQNRHYFIEINPRIQVEHTITEEITXXXXXXXXXXXXXXXTLEQLGLM 346
A T E+L + +YF+E+NPR+QVEH +TE I L Q+ +
Sbjct: 434 VGAATVEYLYSMDTGEYYFLELNPRLQVEHPVTEWIAEVNLPAAQVAVGMGIPLWQIPEI 493
Query: 347 Q-----------------------------DKITTRGFAIQCRITTEDPSKNFQPDTGRI 377
+ + + +G + R+T+EDP F+P +G I
Sbjct: 494 RRFYGMEHGGGYDSWRKTSVVASPFDFDEAESLRPKGHCVAVRVTSEDPDDGFKPTSGEI 553
Query: 378 ------------DVYRSAGGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRK 425
+ G G+ + F ++ + + G + +
Sbjct: 554 QELSFKSKPNMWSYFSVKSGGGIHEFSDSQF--GKLNEKFGMLGQHVFAFGESRSVAIAN 611
Query: 426 MLRALIEFRIRG-VKTNIPFLLTLLTHPVFKSGEYWTTFID 465
M+ AL E +IRG ++TN+ + + LL ++ + T ++D
Sbjct: 612 MVLALKEIQIRGDIRTNVDYTIDLLHASDYRENKIHTGWLD 652
>CE14734 [I] KOG0368 Acetyl-CoA carboxylase
Length = 2054
Score = 170 bits (430), Expect = 1e-41
Identities = 139/507 (27%), Positives = 222/507 (43%), Gaps = 69/507 (13%)
Query: 20 KLLVANRGEIPIRIFRTAHELSMKT---------VAIYSHEDRLSMHRLKADEAYVIGEQ 70
+LLVA G +R TA + T V + + ++ SM + E
Sbjct: 50 RLLVATNGIAAMRCLMTAKKFLHHTFRNDNLIHFVCMTTEDEIQSMSESLRMPNITLAES 109
Query: 71 GKYTPVGAYLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPAAVID 130
T + +DEI+ A + V+ + G+G SEN + ++ I ++GPPA+ +
Sbjct: 110 PSGTNKNNFANVDEILKHAIKYEVDAVWAGWGHASENPDLPRRLNDHNIAFIGPPASAMF 169
Query: 131 SVGDKVSARNLAEKANVPVVP--GTPGPIETVEEA-------------QAFVDKY----- 170
S+GDK+++ +A+ VP V G+ +E++E + QA V Y
Sbjct: 170 SLGDKIASTIIAQTVGVPTVAWSGSGITMESIERSRGDFVVVPEDLLEQACVANYKEGLE 229
Query: 171 -------GFPVIIKAAFXXXXXXXXXXXXXDDISDAFQRAKSEAITAFGNGTCFIERFLD 223
GFP++IKA+ +D F+ E F+ + +D
Sbjct: 230 ALKTHNIGFPLMIKASEGGGGKGIRKCTKVEDFKSMFEEVAQEV----QGSPIFLMKCVD 285
Query: 224 KPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKVVEVAPAKTLPEEVRDAILTDAVKLAK 283
+HIEVQLLAD Y NV+ ++ RDCS+QRR QK++E APA +R ++ DAV+LAK
Sbjct: 286 GARHIEVQLLADRYENVISVYTRDCSIQRRCQKIIEEAPAIIASSHIRKSMQEDAVRLAK 345
Query: 284 EAGYRNAGTAEFLV----DNQNRH-YFIEINPRIQVEHTITEEITXXXXXXXXXXXXXXX 338
GY +AGT E+L + Q H YF+E+NPR+QVEH TE ++
Sbjct: 346 YVGYESAGTVEYLYLPASEGQEEHYYFLELNPRLQVEHPTTEMVSNISIPAIQLQIAMGL 405
Query: 339 TLEQL--------------GLMQDK--ITTRGFAIQCRITTEDPSKNFQPDTGRIDVYRS 382
L ++ + D+ + T+ AI RIT E+P +F+P TG++
Sbjct: 406 PLHKIKDIRKLYDLPIDGDSELPDEVLVDTKLHAIAARITCENPDDSFRPSTGKVYEINF 465
Query: 383 AGGNGVRLDGGNAFA---GSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIEFRIR-GV 438
D F+ GS + DS G++ M L IR
Sbjct: 466 PSSQ----DAWAYFSVGRGSSVHQFADSQFGHIFTRGTSRTEAMNTMCSTLKHMTIRSSF 521
Query: 439 KTNIPFLLTLLTHPVFKSGEYWTTFID 465
T + +L+ L+ F + + T ++D
Sbjct: 522 PTQVNYLVDLMHDADFINNAFNTQWLD 548
>Hs4501855 [I] KOG0368 Acetyl-CoA carboxylase
Length = 2483
Score = 169 bits (428), Expect = 2e-41
Identities = 138/514 (26%), Positives = 228/514 (43%), Gaps = 85/514 (16%)
Query: 20 KLLVANRGEIPIRIFRTA---------HELSMKTVAIYSHEDRLSMHRLKADEAYV-IGE 69
K+L+AN G ++ R+ +E +++ V + + ED LKA+ Y+ + +
Sbjct: 261 KVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVRMVTPED------LKANAEYIKMAD 314
Query: 70 QGKYTPVGA----YLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPP 125
P G Y ++ I++IAK + + G+G EN + E + +G+ ++GPP
Sbjct: 315 HYGPAPGGPNNNNYANVELIVDIAKRIPLQAVWAGWGHALENPKLPELLCKNGVAFLGPP 374
Query: 126 AA-VIDSVGDKVSARNLAEKANVPVVPGT---------------------------PGPI 157
+ +GDK+++ +A+ VP +P + G +
Sbjct: 375 RLRPMVGLGDKIASTVVAQTLQVPTLPRSGSALTVEWTEDDLQQGKRISVPEDVYDKGCV 434
Query: 158 ETVEEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISDAFQRAKSEAITAFGNGTCF 217
+ V+E ++ GFP++IKA+ +D F++ +SE F
Sbjct: 435 KDVDEGLEAAERIGFPLMIKASEGGGGKGIRETESAEDFPILFRQVQSE----IPGSPIF 490
Query: 218 IERFLDKPKHIEVQLLADNYGNVVHLFERDCSVQRRHQKVVEVAPAKTLPEEVRDAILTD 277
+ + +H+EVQ+LAD YGN V LF RDCS+QRRHQK+VE APA P + + +
Sbjct: 491 LMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQC 550
Query: 278 AVKLAKEAGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHTITEEITXXXXXXXXXXXXXX 337
A++LAK GY +AGT E+L +F+E+NPR+QVEH TE I
Sbjct: 551 AIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMG 610
Query: 338 XTLEQLGLMQ-------------------DKITTRGFAIQCRITTEDPSKNFQPDTGRID 378
L +L ++ RG I RIT+E+P + F+P +G +
Sbjct: 611 APLHRLKDIRLLYGESPWGDSPISFENSAHLPCPRGHVIATRITSENPDEGFKPSSGTVQ 670
Query: 379 V--YRSA----GGNGVRLDGGNAFAGSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIE 432
+RS+ G V GG + S C G + M+ AL E
Sbjct: 671 ELNFRSSKNVWGYFTVAATGG-------LHEFAISQFGHCFSWGENRKEAISNMVVALKE 723
Query: 433 FRIRG-VKTNIPFLLTLLTHPVFKSGEYWTTFID 465
+RG +T + +L+ LL F++ T ++D
Sbjct: 724 LSLRGDFRTTVEYLINLLETESFQNNYIDTGWLD 757
>CE20115 [I] KOG0368 Acetyl-CoA carboxylase
Length = 1657
Score = 168 bits (426), Expect = 4e-41
Identities = 137/494 (27%), Positives = 216/494 (42%), Gaps = 62/494 (12%)
Query: 20 KLLVANRGEIPIRI-----------FRTAHELSMKTVAIYSHEDRLSMHRLKADEAYVIG 68
++LVAN G ++ F T+ +S +A E R + H LK + V+
Sbjct: 32 RILVANNGLAAMKCLISIRQWLQNQFGTSGVVSFVCIAT-EDEMRSASHYLKLADEIVMA 90
Query: 69 EQGKYTPVGAYLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPPAAV 128
G + + D II +A V+ ++ G+G SEN E ++ + I ++GP
Sbjct: 91 PAGSNSK--NFANCDVIIRLAVEAQVDAVYVGWGHASENPELCRRLELNNIIFIGPSEKS 148
Query: 129 IDSVGDKVSARNLAEKANVPVVPGT--------------------PGPIETVEEAQAFVD 168
I + GDK+ + +A+ +P V T I V+E ++
Sbjct: 149 IIASGDKIVSTIIAQSIGMPTVTWTGSGVKVEECVDFEHYHELRSKATIRNVKEGLEAIE 208
Query: 169 KYGF--PVIIKAAFXXXXXXXXXXXXXDDISDAFQRAKSEAITAFGNGTCFIERFLDKPK 226
KYG P++IKA+ DD F+ + E F N F+ + +D +
Sbjct: 209 KYGIGVPMMIKASEGGGGKGIRKCENMDDFKRLFKEVELE----FPNSPIFLMKCMDGAR 264
Query: 227 HIEVQLLADNYGNVVHLFERDCSVQRRHQKVVEVAPAKTLPEEVRDAILTDAVKLAKEAG 286
H+E+Q+L D +G+V+ L RDC++QRR QKV+E APA +P EV + DA+ A G
Sbjct: 265 HVEIQILGDKHGDVIALSSRDCTIQRRCQKVIEEAPASIVPGEVMQKMKKDAIAFANFVG 324
Query: 287 YRNAGTAEFL-VDNQNRHYFIEINPRIQVEHTITEEITXXXXXXXXXXXXXXXTLEQLGL 345
Y +AGT E L + N ++F+E+NPR+QVEH TE I L+ +
Sbjct: 325 YYSAGTVELLFIPTTNEYFFLELNPRLQVEHPCTESICDVNVPALQYQIAMGRKLKDIPC 384
Query: 346 M----QDKITTRGFAIQC---RITTEDPSKNFQPDTGRIDVYRSAGGNGVRLDGGNAFA- 397
+ + + T + C R+T EDP+ F P TG + RS N A+A
Sbjct: 385 IKRFREREATGNAGGVHCMAARVTCEDPNDRFLPSTGTV---RSLKFNST----SKAWAY 437
Query: 398 -----GSVISPHYDSMLVKCSCSGSTYEIVRRKMLRALIEFRIRGV-KTNIPFLLTLLTH 451
GS + DS + G + L +I T +L+ LL+
Sbjct: 438 FSLSDGSTVHEFADSQIGHVFARGRDRNEAIANLKHGLQNLKIDATFPTQSDYLIDLLSL 497
Query: 452 PVFKSGEYWTTFID 465
FKS +Y T ++D
Sbjct: 498 EKFKSNQYDTQWLD 511
>SPBC215.08c [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 1160
Score = 57.8 bits (138), Expect = 1e-07
Identities = 64/326 (19%), Positives = 124/326 (37%), Gaps = 21/326 (6%)
Query: 35 RTAHELSMKTVAIYSHEDRLSMHRLKADEAYVIGEQGKYTPVGAYLAIDEIINIAKSHGV 94
+ E S+ T+ I + + ADE Y + +Y + +I G+
Sbjct: 114 KALRESSVHTILINPNIATIQSSHSLADEIYFLPVTAEY--------LTHLIERENPDGI 165
Query: 95 NFIHPGYGFLSENSEFAEK--VAASGITWVGPPAAVIDSVGDKVSARNLAEKANVPVVPG 152
G L+ + + A + + +G P + + + D+ + N+P+
Sbjct: 166 LLTFGGQTALNVGIQLDDMGVFARNHVKVLGTPISTLKTSEDRDLFAKALNEINIPIAES 225
Query: 153 TPGPIETVEEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISDAFQRAKSEAITAFG 212
+ TV+EA +K +PVII++A+ +++ AKS ++T
Sbjct: 226 VA--VSTVDEALQAAEKVSYPVIIRSAYSLGGLGSGFANNKEELQS--MAAKSLSLTP-- 279
Query: 213 NGTCFIERFLDKPKHIEVQLLADNYGNVVHL--FERDCSVQRRHQKVVEVAPAKTLPEEV 270
+E+ L K +E +++ D N + + E + + VAP++TL +E
Sbjct: 280 --QILVEKSLKGWKEVEYEVVRDAANNCITVCNMENFDPLGIHTGDSIVVAPSQTLSDEE 337
Query: 271 RDAILTDAVKLAKEAGYRNAGTAEF-LVDNQNRHYFIEINPRIQVEHTITEEITXXXXXX 329
+ T A+K+ + G ++ L N + IE+N R+ + + T
Sbjct: 338 YHMLRTAAIKIIRHLGVVGECNVQYALSPNSLEYRVIEVNARLSRSSALASKATGYPLAY 397
Query: 330 XXXXXXXXXTLEQLGLMQDKITTRGF 355
TL +L K TT F
Sbjct: 398 TAAKIALGHTLPELPNAVTKTTTANF 423
>Hs18105007 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2225
Score = 56.6 bits (135), Expect = 2e-07
Identities = 50/251 (19%), Positives = 107/251 (41%), Gaps = 21/251 (8%)
Query: 82 IDEIINIAKSHGVNFIHPGYGFLSENSEFAEK--VAASGITWVGPPAAVIDSVGDKVSAR 139
+ ++I + GV G L+ E + +A G+ +G P I+ D+ +
Sbjct: 460 VTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFA 519
Query: 140 NLAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFXXXXXXXXXXXXXDDISDA 199
+ V P ++E+AQA ++ G+PV+++AAF +++S
Sbjct: 520 ARMAEIGEHVAPSEAA--NSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELSAL 577
Query: 200 FQRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHLFERDCSVQR------R 253
A + +++ L K IE +++ D YGN V + C+++
Sbjct: 578 VAPAFAH------TSQVLVDKSLKGWKEIEYEVVRDAYGNCVTV----CNMENLDPLGIH 627
Query: 254 HQKVVEVAPAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVDNQN-RHYFIEINPRI 312
+ + VAP++TL + + A+K+ + G ++ ++ ++ ++Y IE+N R+
Sbjct: 628 TGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARL 687
Query: 313 QVEHTITEEIT 323
+ + T
Sbjct: 688 SRSSALASKAT 698
>YJL130c [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2214
Score = 52.4 bits (124), Expect = 4e-06
Identities = 64/321 (19%), Positives = 126/321 (38%), Gaps = 30/321 (9%)
Query: 17 EKNKLLVANRGEIPI-----------RIFRTAHELSMKTVAIYSHEDRLSMHRLKADEAY 65
E K+LV G + I + + E + T+ I + + + AD+ Y
Sbjct: 437 EAKKVLVLGSGGLSIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLADKVY 496
Query: 66 VIGEQGKYTPVGAYLAIDEIINIAKSHGVNFIHPGYGFLSENSEFAEKVAASGITWVGPP 125
+ PV A + ++I + + G LS ++ A G+ +G P
Sbjct: 497 -------FVPVTAEF-VRKVILHERPDAIYVTFGGQTALSVGIAMKDEFEALGVKVLGTP 548
Query: 126 AAVIDSVGDKVSARNLAEKANVPVVPGTPGPIETVEEAQAFVDKYGFPVIIKAAFXXXXX 185
I + D+ N ++ N +V+EA A V + GFPVI++AA+
Sbjct: 549 IDTIITTEDRELFSNAIDEINEKCAKSQAA--NSVDEALAAVKEIGFPVIVRAAYALGGL 606
Query: 186 XXXXXXXXDDISDAFQRAKSEAITAFGNGTCFIERFLDKPKHIEVQLLADNYGNVVHL-- 243
++ D A S + +E+ + K +E +++ D + N + +
Sbjct: 607 GSGFANNEKELVDLCNVAFS------SSPQVLVEKSMKGWKEVEYEVVRDAFDNCITVCN 660
Query: 244 FERDCSVQRRHQKVVEVAPAKTLPEEVRDAILTDAVKLAKEAGYRNAGTAEFLVDNQNRH 303
E + + VAP++TL +E + + T AV + + G ++ ++ ++
Sbjct: 661 MENFDPLGIHTGDSIVVAPSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPVSKD 720
Query: 304 Y-FIEINPRIQVEHTITEEIT 323
Y IE+N R+ + + T
Sbjct: 721 YCIIEVNARLSRSSALASKAT 741
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,126,398
Number of Sequences: 60738
Number of extensions: 2891145
Number of successful extensions: 7122
Number of sequences better than 1.0e-05: 27
Number of HSP's better than 0.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 6969
Number of HSP's gapped (non-prelim): 67
length of query: 1173
length of database: 30,389,216
effective HSP length: 118
effective length of query: 1055
effective length of database: 23,222,132
effective search space: 24499349260
effective search space used: 24499349260
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)