ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1579 good J KOG2102 Translation, ribosomal structure and biogenesis Exosomal 3'-5' exoribonuclease complex, subunit Rrp44/Dis3
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1579 559419 556471 -983
(983 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR287c [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subun... 643 0.0
At5g02250 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex sub... 107 1e-22
ECU03g0700 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex su... 81 9e-15
SPAC2C4.07c [J] KOG2102 Exosomal 3'-5' exoribonuclease complex s... 75 5e-13
Hs22045556 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex su... 72 3e-12
7291934 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subun... 72 3e-12
SPBC26H8.10 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex s... 69 4e-11
7301148 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subun... 69 5e-11
CE05214 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subun... 64 9e-10
At1g77680 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex sub... 63 3e-09
Hs19115966 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex su... 62 3e-09
At2g17510 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex sub... 61 1e-08
YOL021c [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subun... 60 2e-08
Hs19923416 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex su... 55 5e-07
SPCC23B6.06 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex s... 53 2e-06
>YMR287c [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subunit
Rrp44/Dis3
Length = 969
Score = 643 bits (1658), Expect = 0.0
Identities = 361/945 (38%), Positives = 550/945 (58%), Gaps = 53/945 (5%)
Query: 39 GTNVTTESLQEDEEVIFFSQDKDILPEVEIKPFRRTKAETLMRFNDRFVQPSIDWYRKVG 98
G ES+ +D F + K + P++E+K + K E R+ DR+V+PS DWY V
Sbjct: 65 GPEKDIESINKD----FLQRTKGLEPDIELKQLPQIKQEFNQRYKDRYVKPSEDWY--VN 118
Query: 99 KSHGENTDKDEFMHLLRNDISSSTLFEETLKWLSKDNYKLRNNTYNGYDTQEIEFYFDPS 158
K L+ +D T K N F P
Sbjct: 119 SWRSLTKPKIPLYKLINSDFQLIT------------KLKAPN-----------PMEFQPV 155
Query: 159 AIVSSTLMPGDICVLKNSPFELLVCVKTPSEAMDARFTFANTDGNVVYAWKTSVHLRFPT 218
++ S L GD +LK P EL +CV PS MD R+TF DG + +A K V LR P
Sbjct: 156 QLMESPLNVGDFVLLKMRPNELAMCVSLPSSTMDPRYTFVTIDGTMCFATKNRVLLRIPH 215
Query: 219 IFNTTELEILQREKLHGYSPVGSVKNDKDVTFVIPTLPRRMLISNVTFRIADAAVQQLPI 278
++Q E H + P+G+VKN + T ++P + R+++ S +I+ A + LPI
Sbjct: 216 KLPAGIHSLIQPESHHKHLPIGTVKNFSNQTNILPIVARQLITSRYPAQISKLAWKDLPI 275
Query: 279 IKKKLELIHRYLQSGSSPWQIPILKLVEICSNLELSNNIEKSIATAFMKSGLSSDALYSL 338
KKL+L+HR LQ+ PWQIP LV + L+L+ ++ K+G+ + L SL
Sbjct: 276 TTKKLQLLHRSLQNYMGPWQIPFFTLVGLVQKLDLNKALDD-------KNGI--NYLTSL 326
Query: 339 ANSHFELSSKVPNKVECSRLLAVYWALLHQQGTQMWGEMTVHRGIFFPSAVTVLPLTKQH 398
N++ ++ +P + ++ YWA++ QQ + +WGE+ ++ + P +VT++PL QH
Sbjct: 327 VNNYHTVND-IP--INSPTFVSTYWAIMQQQESNLWGEIHLNTALLSPISVTIIPLKSQH 383
Query: 399 LHYHNIIHKLRQHGGVRINRIAALINENDLASLNKSFPYIVPLLRDYAAGNLEHNDTITS 458
L+Y +I KL + +N+ L+NE ++ +P ++ LL+D+AAGN +N I +
Sbjct: 384 LYYAQVIEKLEANSYREVNKFVKLVNERKYRDISALYPSVIQLLKDFAAGNFHNNGIIVA 443
Query: 459 LISSLFRKLDEYKELNISRDVCFDLLKRINPSEPPNPLLINHELQLPVNNERVKLEQKIY 518
LIS +FRK++ YK+ +I+RD+C DL+ I P+ PNPLL+N +L LP +++ VK +QK+Y
Sbjct: 444 LISKIFRKIERYKDCDITRDICQDLINEITPNSIPNPLLLNMDLALPASSKLVKWQQKLY 503
Query: 519 DLA----VPPKIEHSAEIRTEYKDLICYCIDSPDAHEIDDAVSIKSLG-GAKYRIYIHVA 573
DL + K + + R ++ DL +CIDS AHEIDD VS+K+ G Y +YIH+A
Sbjct: 504 DLTNIEELQWKKSGTDDDRYDFGDLRVFCIDSETAHEIDDGVSVKNYGRDGLYTLYIHIA 563
Query: 574 DPASLFPEA-NEDGTTINSPVLDIAYQRAFTTYLPDKVFPMLPTTYARSSDLGQFGKPTK 632
DP S+FPE+ N D I++ +L++A +R+FTTYLPD V PMLP + SDLG+ G+ TK
Sbjct: 564 DPTSMFPESTNVDIEGISTDILNVALKRSFTTYLPDTVVPMLPQSICHLSDLGKQGQRTK 623
Query: 633 AVTFSVDCTFS---KSKGLCLLKDSLKVELSVLHKSTRITYEAVDELLDEPTTKPKSGKH 689
++FSVD + K + ++ DS K+ ++ + TYE VD +L P ++ K
Sbjct: 624 TISFSVDVKITSKCSGKSIEIMYDSFKIRKGIVSNFPKATYEDVDRILGTPNSEASPVK- 682
Query: 690 EDLKTLFYIAKALRRQRIVDGGAVVF-ENSSTGIVSLSPDDNSELVEVSFKDQIETKSTI 748
+DL++L I+K LR QRI + AV+F E + G+V L+ D EL EV+F DQ ET STI
Sbjct: 683 KDLESLSMISKLLREQRIKNSNAVIFGEGFNKGLVMLNADSEGELTEVTFSDQEETLSTI 742
Query: 749 LVSELMILANSLTASYFEENQIPGIYRGYRPLNVVEDATSVPEWVKAKTQENKIISKADI 808
LVSE+MILAN+LT YF EN+I G++R Y+ L + E A + + T++ DI
Sbjct: 743 LVSEMMILANTLTGRYFAENKIGGVFRCYKQLPLGEVAQQQYDSMITSTKKGIFPKLKDI 802
Query: 809 AKMKSFLTSSFYSSLPTPHDMLGTSHYLTITSPLRRFPDLVNHLQLHRTLKGLPLLYKQS 868
K+ S L SSFY+ P H+M+G YLT+TSPLRRFPDL+NHLQ+HR L+ PL + Q+
Sbjct: 803 VKLSSLLNSSFYTGRPFRHEMIGAKQYLTVTSPLRRFPDLINHLQIHRHLQKKPLCFNQT 862
Query: 869 QLDGMVWHILTRDVTLKNASVDAQRYWTLRFLKKEIEDPTKNNWKLQITSLTDNGYAHCV 928
Q+D ++W I +R LK AS ++ YWTL +LKK + + + + +TS+ NG+ CV
Sbjct: 863 QIDSLIWPIQSRADILKRASRNSSTYWTLNYLKKLTKLEPERTFDVMVTSVPQNGFTGCV 922
Query: 929 ILDKAFAVGQLKIN-LNKNPPLVGDQISDCEISNIQCLDGILQFE 972
D +FA G LK++ + + P++GD + +C+IS I CL+G+L+ E
Sbjct: 923 FPDLSFARGTLKLHPSSMHYPMIGDIVKNCKISKIDCLEGMLELE 967
>At5g02250 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subunit
Rrp44/Dis3
Length = 782
Score = 107 bits (266), Expect = 1e-22
Identities = 110/413 (26%), Positives = 176/413 (41%), Gaps = 58/413 (14%)
Query: 495 PLLINHEL---QLPVNNERVKLEQKIYDLAVPPKIEHSAEIRTEYKDLICYCIDSPDAHE 551
P+ +N EL LP ++ E L+ I+ A R + L Y ID +A E
Sbjct: 360 PVHVNLELLKLNLPTHHSEAITEAAEALLSESSDID--AVRRIDLTHLKVYAIDVDEADE 417
Query: 552 IDDAVSIKSLGGAKYRIYIHVADPASLFPEANEDGTTINSPVLDIAYQRAFTTYLPDKVF 611
+DDA+S L + +I+IHVADPA T S V A +R + +LP +
Sbjct: 418 LDDALSATRLQDGRIKIWIHVADPARY--------VTPGSKVDREARRRGTSVFLPTATY 469
Query: 612 PMLPTTYARSSDLGQFGKPTKAVTFSVDCTFSKSKGLCLLKDSLKVELSVLHKSTRITYE 671
PM P A + G+ AV+ SV L D EL LH + E
Sbjct: 470 PMFPEKLAMEGMSLRQGENCNAVSVSV----------VLRSDGCASEL--LH--LNLEEE 515
Query: 672 AVDELLDEPTTKPKSGKHEDLKTLFYIAKALRRQRIVDGGAVVFENSSTGIVSLSPDDNS 731
A +LL E +I RR++ GAV T I ++P+D
Sbjct: 516 AELKLLSEAA---------------FIRSQWRREQ----GAVDTTTLETRIKVVNPEDPE 556
Query: 732 ELVEVSFKDQIETKSTILVSELMILANSLTASYFEENQIPGIYRGYRPLNVVEDATSVPE 791
L+ + ++Q + + LV E+MIL + A++ ++ IP YRG N+ D ++
Sbjct: 557 PLINLYVENQADL-AMRLVFEMMILCGEVVATFGSQHNIPLPYRGQPQSNI--DVSAFAH 613
Query: 792 WVKAKTQENKIISKADIAKMKSFLTSSFYSSLPTPHDMLGTSHYLTITSPLRRFPDLVNH 851
+ + + I+ A+M P H +LG Y+ TSP+RR+ DL H
Sbjct: 614 LPEGPVRSSSIVKVMRAAEMN--------FRCPVRHGVLGIPGYVQFTSPIRRYMDLTAH 665
Query: 852 LQLHRTLKGLP-LLYKQSQLDGMVWHILTRDVTLKNASVDAQRYWTLRFLKKE 903
Q+ L+G + +L+G+ + + ++ S RYW + FL+++
Sbjct: 666 YQIKAFLRGGDNFPFSAGELEGIAASVNMQSKVVRKLSNTGLRYWVIEFLRRQ 718
>ECU03g0700 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subunit
Rrp44/Dis3
Length = 835
Score = 80.9 bits (198), Expect = 9e-15
Identities = 99/381 (25%), Positives = 162/381 (41%), Gaps = 48/381 (12%)
Query: 502 LQLPVNNERVKLEQKIYDLAVPPKIEHSAEIRTEYKDLICYCIDSPDAHEIDDAVSIKSL 561
L++P NE + +K Y+ E R ++++L ID PD +IDDA+ + L
Sbjct: 366 LRVPWMNEDIFGMEKAYN-------EVREGTREDFRELSIVSIDPPDCEDIDDALHCRLL 418
Query: 562 GGAKYRIYIHVADPASLFPEANEDGTTINSPVLDIAYQRAFTTYLPDKVFPMLPTTYARS 621
+ + +H+AD T S + IA R T YLP+ MLP A S
Sbjct: 419 PNGNWEVGVHIADVTYY--------VTKGSEIDKIAADRGTTIYLPEWRIDMLPP--ALS 468
Query: 622 SDLGQFGKPTKAVTFSVDCTFSKSKGLCLLKDSLKVELSVLHKSTRITYEAVDELLDEPT 681
+DL FSV S + + S S Y+AV L+D
Sbjct: 469 TDLCSLVAGKDRAAFSVVWEMSSDVRVVRTHFCRSLIRSKRSFSYNEAYDAVQGLVDAGD 528
Query: 682 TKPKSGKHEDLKTLFYIAKALRRQRIVDGGAVVFENSSTGIVSLSPDDNSELVEVSFKDQ 741
+S L+ L I++ LR +R G + S+ +V E F+ +
Sbjct: 529 EVSRS-----LRMLLEISRVLRSRRFAKGS---LDLSTRQLV---------FREGGFEMK 571
Query: 742 IETKSTILVSELMILANSLTASY-FEENQIPGIYRGYRPLNVVEDA----TSVPEWVKAK 796
+ LV E M+LAN AS+ + + + R + P +V++ TS P +
Sbjct: 572 EYFPTNFLVEEFMVLANISVASFIYHHHPDSSLLRKHPPPSVLDIGLDIDTSSPRALSES 631
Query: 797 TQENKIISKADIAK---MKSFLTSSFYSSLPTP---HDMLGTSHYLTITSPLRRFPDLVN 850
++ + + K D+AK ++S + + S TP H L T Y TSP+RR+ D++
Sbjct: 632 LEKMEGVRK-DLAKRMLIRSMNQAVYVVSGETPSLHHYGLATPIYTHFTSPIRRYADIIV 690
Query: 851 HLQLHRTLKGLPLLYKQSQLD 871
H L+ L+ P K++Q++
Sbjct: 691 HRILNHILQTAPT--KEAQIN 709
>SPAC2C4.07c [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subunit
Rrp44/Dis3
Length = 927
Score = 75.1 bits (183), Expect = 5e-13
Identities = 89/365 (24%), Positives = 142/365 (38%), Gaps = 57/365 (15%)
Query: 533 RTEYKDLICYCIDSPDAHEIDDAVSIKSLGGAKYRIYIHVADPASLFPEANEDGTTINSP 592
R + ++ + ID A ++DDAVS ++L Y + +H+AD +S
Sbjct: 441 RRDLRNELIITIDPETARDLDDAVSCRALDNGTYEVGVHIADVTHFVKP--------DSA 492
Query: 593 VLDIAYQRAFTTYLPDKVFPMLPTTYARSSDLGQFGKPTKAVTFSVDCTFSKSKGLCLLK 652
+ A RA T YL K PMLP L + + FSV S G + K
Sbjct: 493 LDKEAASRATTVYLVQKAIPMLPPLLCER--LCSLNPNVERLAFSVFWKLD-SNGKEIGK 549
Query: 653 DSLKVELSVLHKSTRITYEAVDELL-----DEPTTKPKSGKHE------DLKTLFYIAKA 701
+V+ R+ Y ++ D+ KP G H + TL I++
Sbjct: 550 RWFGK--TVIKTCARLAYSEAQGVIEGKSWDDAVGKPIGGTHTPKDVETSILTLCEISRK 607
Query: 702 LRRQRIVDGGAVVFENSSTGIVSLSPDDNSELVEVSFKDQIETKSTILVSELMILANSLT 761
LR+ R G + NS+ L EV +T + L+ E M+LAN
Sbjct: 608 LRKDRFAKGAVEI--NSTELKFQLDEYGMPNKCEV----YEQTDANHLIEEFMLLANRSV 661
Query: 762 ASYFEEN----------------QIPGIYRGYRPLNVVEDATSVPEW----VKAKTQENK 801
A + +N QI + +N DA+S + V+ ++ N+
Sbjct: 662 AEHISKNFSNNSLLRRHASPKEKQINEFCHFLKSMNFDFDASSSAAFNASMVRLRSTFNE 721
Query: 802 IISKA-------DIAKMKSFLTSSFYSSLPTPHDMLGTSHYLTITSPLRRFPDLVNHLQL 854
+ + + + + F T F H L +HY TSP+RR+PD++ H L
Sbjct: 722 ELVELFENMAVRSLNRAEYFCTGDFGEKTDWHHYALSFNHYTHFTSPIRRYPDIIVHRLL 781
Query: 855 HRTLK 859
R+LK
Sbjct: 782 ERSLK 786
>Hs22045556 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subunit
Rrp44/Dis3
Length = 885
Score = 72.4 bits (176), Expect = 3e-12
Identities = 91/380 (23%), Positives = 152/380 (39%), Gaps = 66/380 (17%)
Query: 522 VPPKIEHSAEIRTEYKDLICYCIDSPDAHEIDDAVSIKSLGGAKYRIYIHVADPASLFPE 581
+PP E ++ R KD I + ID A ++DDA+S K L +++ +H+AD + PE
Sbjct: 363 IPP--EEFSKRRDLRKDCI-FTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPE 419
Query: 582 ANEDGTTINSPVLD-IAYQRAFTTYLPDKVFPMLPTTYARSSDLGQFGKPTKAVTFSVDC 640
++ LD +A +RA + YL KV PMLP +L + +TFSV
Sbjct: 420 GSD---------LDKVAAERATSVYLVQKVVPMLPRLLC--EELCSLNPMSDKLTFSVIW 468
Query: 641 TFSKSKGLCLLKDSLKVELSVLHKSTRITYEAVDELLDEPTTKPKSGK------------ 688
T + + +++ T+++YE +++ PT K + +
Sbjct: 469 TLTPEGKIL----DEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEE 524
Query: 689 -HEDLKTLFYIAKALRRQRIVDGGAVVFENSSTGIVSLSPDDNSELVEVSFKDQIETKST 747
H+ + L IAK LR+QR VDG + + ++ + D + L + + +S
Sbjct: 525 VHQAVLNLHGIAKQLRQQRFVDGALRLDQLK----LAFTLDHETGLPQGCHIYEYR-ESN 579
Query: 748 ILVSELMILANSLTASYF----------------EENQIPGIYRGYRPLNVVEDATSVPE 791
LV E M+LAN A + + + + + D +S
Sbjct: 580 KLVEEFMLLANMAVAHKIHRAFPEQALLRRHPPPQTRMLSDLVEFCDQMGLPVDFSSAGA 639
Query: 792 WVKAKTQ-----ENKIISKADIAKMKS--------FLTSSFYSSLPTPHDMLGTSHYLTI 838
K+ TQ + + K + M S F + H L Y
Sbjct: 640 LNKSLTQTFGDDKYSLARKEVLTNMCSRPMQMALYFCSGLLQDPAQFRHYALNVPLYTHF 699
Query: 839 TSPLRRFPDLVNHLQLHRTL 858
TSP+RRF D++ H L L
Sbjct: 700 TSPIRRFADVLVHRLLAAAL 719
>7291934 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subunit
Rrp44/Dis3
Length = 968
Score = 72.4 bits (176), Expect = 3e-12
Identities = 71/269 (26%), Positives = 122/269 (44%), Gaps = 39/269 (14%)
Query: 517 IYDLAVPPKIEHSAEIRTEYKDLICYCIDSPDAHEIDDAVSIKSLGGAKYRIYIHVADPA 576
IY PP + R + + + + ID A ++DDAVSI+ LG +Y I +H++D +
Sbjct: 508 IYSQPPPPISQEDLRQRKDLRKMCIFTIDPMTARDLDDAVSIEKLGDNEYEIGVHISDVS 567
Query: 577 SLFPEANEDGTTINSPVLDIAYQRAFTTYLPDKVFPMLPTTYARSSDL--GQFGKPTKAV 634
E NE + +I +R+ + YL ++V MLP + L GQ
Sbjct: 568 HFLIEDNE--------LDNIVKERSTSIYLANEVIHMLPQSLCMRCSLLPGQ-----DKF 614
Query: 635 TFSVDCTFSKSKGLCLLKDSLKVEL--SVLHKSTRITYEAVDELLDEPT---------TK 683
FSV + KG+ L K K E +V++ ++ YE +++D P T
Sbjct: 615 AFSVFWRMN-GKGVMLQK---KPEFCRTVINSCSQFAYEHAQKIIDNPNERFTENDFPTI 670
Query: 684 PKSGKHEDLKT----LFYIAKALRRQRIVDGGAVVFENSSTGIVSLSPDDNSELVEVSFK 739
+D++ L IA ++R+ R+ D GA+ N+ + L P L SF+
Sbjct: 671 LNGFNPDDIRNRVLWLHDIASSIRKTRL-DNGALTINNAKLRFL-LDPITGEPL---SFE 725
Query: 740 DQIETKSTILVSELMILANSLTASYFEEN 768
+ + ++ L+ E M+LAN A + ++
Sbjct: 726 VEKQREANRLIEEFMLLANQAVARFIHDS 754
>SPBC26H8.10 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subunit
Rrp44/Dis3
Length = 970
Score = 68.9 bits (167), Expect = 4e-11
Identities = 86/350 (24%), Positives = 151/350 (42%), Gaps = 50/350 (14%)
Query: 533 RTEYKDLICYCIDSPDAHEIDDAVSIKSLGGAKYRIYIHVADPASLFPEANEDGTTINSP 592
R +++D + ID P +IDDA+ L Y + +H+AD + F + N T+++S
Sbjct: 496 RKDFRDKLICSIDPPGCQDIDDALHACVLPNGNYEVGVHIAD-VTHFVKPN---TSMDSE 551
Query: 593 VLDIAYQRAFTTYLPDKVFPMLPTTYARSSDLGQFGKPTKAVTFSVDCTFSKSKGLCLLK 652
A R T YL DK MLP +DL + FS C + + ++K
Sbjct: 552 ----AASRGTTVYLVDKRIDMLPMLL--GTDLCSLRPYVERFAFS--CIWEMDENANIIK 603
Query: 653 DSLKVELSVLHKSTRITYEAVDELLDEPTTKPKSGKHEDLKTLFYIAKALRRQRIVDGGA 712
+ SV+ +Y +D+ K + + ++ L ++K L+++R+ +G
Sbjct: 604 --VHFTKSVIASKEAFSYADAQARIDD--QKMQDPLTQGMRVLLKLSKILKQKRMDEGAL 659
Query: 713 VVFENSSTGIVSLSPD-DNSELVEVSFKDQIETKSTILVSELMILANSLTAS--YFEENQ 769
N ++ V + D + S+ ++V K +ET S LV E M+LAN A Y Q
Sbjct: 660 ----NLASPEVRIQTDNETSDPMDVEIKQLLETNS--LVEEFMLLANISVAQKIYDAFPQ 713
Query: 770 IPGIYRGYRP----LNVVEDATSVPEWVKAKTQENKIISKA----------------DIA 809
+ R P + ++D V + + K +K ++K+ I
Sbjct: 714 TAVLRRHAAPPLTNFDSLQDILRVCKGMHLKCDTSKSLAKSLDECVDPKEPYFNTLLRIL 773
Query: 810 KMKSFLTSSFYSS--LPTP---HDMLGTSHYLTITSPLRRFPDLVNHLQL 854
+ L++ ++ S P H L + Y TSP+RR+ D++ H QL
Sbjct: 774 TTRCMLSAEYFCSGTFAPPDFRHYGLASPIYTHFTSPIRRYADVLAHRQL 823
>7301148 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subunit
Rrp44/Dis3
Length = 982
Score = 68.6 bits (166), Expect = 5e-11
Identities = 67/233 (28%), Positives = 103/233 (43%), Gaps = 23/233 (9%)
Query: 533 RTEYKDLICYCIDSPDAHEIDDAVSIKSLGGAKYRIYIHVADPASLFPEANEDGTTINSP 592
R + +DL +D P +IDDA+ K L + +H+AD + N
Sbjct: 474 RVDLRDLYICSVDPPGCTDIDDALHCKELPNGNLEVGVHIADVSHFIRPGN--------- 524
Query: 593 VLDI-AYQRAFTTYLPDKVFPMLPTTYARSSDLGQFGKPTKAVTFSVDCTFSKSKGLCLL 651
LD+ A R T YL K M+P SS+L + FS C + +L
Sbjct: 525 ALDMEAAARGTTVYLVGKRIDMVPELL--SSNLCSLVGGVERFAFS--CVWEVDNEANVL 580
Query: 652 KDSLKVELSVLHKSTRITYEAVDELLDEPTTKPKSGKHEDLKTLFYIAKALRRQRIVDGG 711
S + SV+ +TYE ++D+ T + + K L+ L +AK L+++R +D G
Sbjct: 581 --SKRFHKSVIKSKRAMTYEEAQNIIDDATQQNEIAK--SLRNLNRLAKILKKRR-MDNG 635
Query: 712 AVVFENSSTGIVSLSPDDNSELVEVSFKDQIETKSTILVSELMILANSLTASY 764
A+V +S I + E +EV K ET S +V E M+LAN A +
Sbjct: 636 ALVL--ASPEIRFQVDSETHEPLEVEVKQMRETNS--MVEEFMLLANITVAEH 684
>CE05214 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subunit
Rrp44/Dis3
Length = 1029
Score = 64.3 bits (155), Expect = 9e-10
Identities = 67/237 (28%), Positives = 104/237 (43%), Gaps = 24/237 (10%)
Query: 533 RTEYKDLICYCIDSPDAHEIDDAVSIKSLGGAKYRIYIHVADPASLFPEANEDGTTINSP 592
R + +DL +D +IDDA+ K +G + + +H+AD GT I+
Sbjct: 479 RVDLRDLTICSVDPLGCTDIDDALHCKQIGEDLFEVGVHIADVTHFV----RPGTAID-- 532
Query: 593 VLDIAYQRAFTTYLPDKVFPMLPTTYARSSDLGQFGKPTKAVTFSVDCTFSKSKGLCLLK 652
D A R T YL D+ MLP SS+L + FS T + S +
Sbjct: 533 --DEAALRGTTVYLCDRRIDMLPCLL--SSNLCSLRGEEERYAFSCIWTMTSSADI---- 584
Query: 653 DSLKVELSVLHKSTRITYEAVDELLDEPTTKPKSGKHEDLKTLFYIAKALRRQRIVDGGA 712
S+K S++ +TYE E++D+P K ++ L+ L ++K L +R GA
Sbjct: 585 QSVKYHKSLIKSKAALTYEKAQEIIDDP--KEQNDVALGLRGLMKLSKVLNARR-TGNGA 641
Query: 713 VVFENSSTGIVSLSPDDNSEL-VEVSFKDQIETKSTILVSELMILAN-SLTASYFEE 767
+ +S V D S +V K ++T S +V E M+LAN S+ EE
Sbjct: 642 LTLASSE---VRFDMDWESRTPKKVMEKQHLDTHS--MVEEFMLLANISVAEKILEE 693
>At1g77680 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subunit
Rrp44/Dis3
Length = 1055
Score = 62.8 bits (151), Expect = 3e-09
Identities = 87/386 (22%), Positives = 152/386 (38%), Gaps = 64/386 (16%)
Query: 527 EHSAEIRTEYKDLICYCIDSPDAHEIDDAVSIKSLGGAKYRIYIHVADPA-SLFPEANED 585
E + R + +DL ID A ++DDA+S++SL G +R+ +H+AD + + PE D
Sbjct: 470 EEEVQRRKDLRDLCVLTIDPSTATDLDDALSVQSLPGGFFRVGVHIADVSYFVLPETALD 529
Query: 586 GTTINSPVLDIAYQRAFTTYLPDKVFPMLPTTYARSSDLGQFGKPTKAVTFSVDCTFSKS 645
A R+ + YL + MLP S ++G + FS+ ++
Sbjct: 530 TE---------ARFRSTSVYLMQRKISMLPPLL--SENVGSLSPGADRLAFSILWDLNRE 578
Query: 646 KGLCLLKDSLKVELSVLHKSTRITYEAVDELLDEPTTKPKSG------------KHEDLK 693
+ + +++ +++Y+ +++D + ++G +K
Sbjct: 579 GDVI----DRWIGRTIIRSCCKLSYDHAQDIIDGKSDVAENGWPALHGSFKWCDVTRSVK 634
Query: 694 TLFYIAKALRRQRIVDGGAVVFENSSTGIVSLSPDDNSELVEVSFKDQIETKSTILVSEL 753
L I+ LR++R GA+ ENS + D++ V F S LV E
Sbjct: 635 QLSEISTTLRQKRF-RNGALQLENSKPVFLF---DEHG--VPYDFVTCSRKGSNFLVEEF 688
Query: 754 MILANSLTASYFEE-NQIPGIYRGYRPLNV------------------VEDATSVPEWVK 794
M+LAN A + + + R + N + + + + ++
Sbjct: 689 MLLANMTAAEVISQAYRASSLLRRHPEPNTRKLKEFEGFCSKHGMDLDISSSGQLQDSLE 748
Query: 795 AKTQENK-------IISKADIAKMK---SFLTSSFYSSLPT-PHDMLGTSHYLTITSPLR 843
T K I++ I M+ F T + S+ H L Y TSPLR
Sbjct: 749 KITGNLKDDSVFVDILNNYAIKPMQLASYFCTGNLKDSVAEWGHYALAVPLYTHFTSPLR 808
Query: 844 RFPDLVNHLQLHRTLKGLPLLYKQSQ 869
R+PD+V H L L+ L KQ Q
Sbjct: 809 RYPDIVVHRALAAALEAEELYSKQKQ 834
>Hs19115966 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subunit
Rrp44/Dis3
Length = 971
Score = 62.4 bits (150), Expect = 3e-09
Identities = 105/462 (22%), Positives = 185/462 (39%), Gaps = 80/462 (17%)
Query: 496 LLINHELQLPVNNERVKLEQKIYDLAVPPKIEHSAEIRTEYKDL----ICYCIDSPDAHE 551
+L+ + + + +E E + P K+ S E + KDL + + ID +
Sbjct: 344 ILVENSISVIPFSEAQMCEMPVNTPESPWKV--SPEEEQKRKDLRKSHLVFSIDPKGCED 401
Query: 552 IDDAVSIKSLGGAKYRIYIHVADPASLFPEANEDGTTINSPVLDIAYQRAFTTYLPDKVF 611
+DD +S+++L + +H+AD NS + A RA T YL D+ +
Sbjct: 402 VDDTLSVRTLNNGNLELGVHIADVTHF--------VAPNSYIDIEARTRATTYYLADRRY 453
Query: 612 PMLPTTYARS--SDLGQFGKPTKAVTFSVDCTFSKSKGLCLLKDSLKVELSVLHKSTRIT 669
MLP+ + S LG + ++ + +D + K + + +++ + ++
Sbjct: 454 DMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGR-------TIIRSAYKLF 506
Query: 670 YEAVDELLD-------------EPTTKPKSGKHEDL----KTLFYIAKALRRQRIVDG-G 711
YEA ELLD + K + K E+L L IA+ +R +R DG G
Sbjct: 507 YEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKR--DGCG 564
Query: 712 AVVFENSSTGIVSLSPDDNSELVEVSFKDQIETKSTILVSELMILANSLTASYFEENQIP 771
A+ E V + DD + ++ K +E T V+E MILAN A E+
Sbjct: 565 ALELEGVE---VCVQLDDKKNIHDLIPKQPLEVHET--VAECMILANHWVAKKIWESFPH 619
Query: 772 GIYRGYRPLNVVEDATSVPEWVKAK-----TQENKIISKA-DIAK----------MKSFL 815
P E + + E KAK T+ NK ++ + D A ++S
Sbjct: 620 QALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMA 679
Query: 816 TSSFYSSL----------PTPHDMLGTSHYLTITSPLRRFPDLVNHLQLHRTL---KGLP 862
T + ++L H L Y TSP+RR+ D+V H L + K +
Sbjct: 680 TQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKME 739
Query: 863 L---LYKQSQLDGMVWHILTRDVTLKNASVDAQRYWTLRFLK 901
+ L+ L+ + HI R+ +++ + + + K
Sbjct: 740 IKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFK 781
>At2g17510 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subunit
Rrp44/Dis3
Length = 955
Score = 60.8 bits (146), Expect = 1e-08
Identities = 99/479 (20%), Positives = 186/479 (38%), Gaps = 57/479 (11%)
Query: 529 SAEIRTEYKDLICYCIDSPDAHEIDDAVSIKSLGGAKYRIYIHVADPASLFPEANEDGTT 588
S +R + + L+ + +D P +IDDA+ SL + + +H+AD + GT
Sbjct: 487 SNPVRQDLRHLLVFSVDPPGCKDIDDALHCTSLPNGNFELGVHIADVTNFV----HPGT- 541
Query: 589 INSPVLDIAYQRAFTTYLPDKVFPMLPTTYARSSDLGQFGKPTKAVTFSVDCTFSKSKGL 648
P+ D A +R + YL ++ MLP + D+ + + FSV S +
Sbjct: 542 ---PLDDEASKRGTSVYLVERRIDMLPKPL--TEDICSLRADVERLAFSVIWEMSPDAEI 596
Query: 649 CLLKDSLKVELSVLHKSTRITYEAVDELLDEPTTKPKSGKHEDLKTLFYIAKALRRQRIV 708
S + S++ S ++Y +D+ ++ DL+ + +AK +R++RI
Sbjct: 597 I----STRFTKSIIKSSAALSYIEAQARMDD--SRLTDSLTTDLRNMNTLAKIMRQRRI- 649
Query: 709 DGGAVVFENSSTGIVSLSPDDNSELVEVSFKDQIETKSTILVSELMILANSLTASYF--- 765
D GA+ ++ + P +N + + + +E +V E M+ AN A
Sbjct: 650 DRGALTLASAEVKF-DIDP-ENHDPLNIGMYQILEANQ--MVEEFMLAANVSVAGQILKL 705
Query: 766 -------------EENQIPGIYRGYRPLNVVEDATS---VPEWVKAKTQENKIISKADIA 809
+ + R + + D +S + + + E+ +K
Sbjct: 706 FPSCSLLRRHPTPTREMLEPLLRTAAAIGLTLDVSSSKALADSLDRAVGEDPYFNKLIRI 765
Query: 810 KMKSFLTSSFY---SSLPTP---HDMLGTSHYLTITSPLRRFPDLVNHLQLHRTL--KGL 861
+T + Y L P H L Y TSP+RR+ D+ H L +L L
Sbjct: 766 LATRCMTQAVYFCSGDLSPPEYHHYGLAAPLYTHFTSPIRRYADVFVHRLLAASLGIYKL 825
Query: 862 PLLYK-QSQLDGMVWHILTRDVTLKNASVDAQRYWTLRFLKKEIEDPTKNNWKLQITSLT 920
P +++ + QL + ++ R + A + + L + + D + ++ +
Sbjct: 826 PTVFQDRPQLTSVADNLNYRHRNAQMAGRASVELYVLIYFRTRPTDE-----EARVVKIR 880
Query: 921 DNGYAHCVILDKAFAVGQLKINLNKNPPLVGDQISDCEISNIQCLDGILQFEPTSRSKI 979
NG+ V + K G + + K GD D E I +DG L + KI
Sbjct: 881 SNGF--IVFVPKYGIEGPVYLT-GKGEKGAGDWYVDEEKQKIVKMDGSLSYSVLQTVKI 936
>YOL021c [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subunit
Rrp44/Dis3
Length = 1001
Score = 59.7 bits (143), Expect = 2e-08
Identities = 101/491 (20%), Positives = 197/491 (39%), Gaps = 65/491 (13%)
Query: 496 LLINHELQLPVNNERVK--LEQKIYDLAVPPKIEHSAEI--------RTEYKDLICYCID 545
LL+ H+++ +++V L + +D P K++ + R + +D + ID
Sbjct: 484 LLLEHDVEYRPFSKKVLECLPAEGHDWKAPTKLDDPEAVSKDPLLTKRKDLRDKLICSID 543
Query: 546 SPDAHEIDDAVSIKSLGGAKYRIYIHVADPASLFPEANEDGTTINSPVLDIAYQRAFTTY 605
P +IDDA+ K L + + +H+AD + GT +++ R + Y
Sbjct: 544 PPGCVDIDDALHAKKLPNGNWEVGVHIADVTHFV----KPGTALDAE----GAARGTSVY 595
Query: 606 LPDKVFPMLPTTYARSSDLGQFGKPTKAVTFSVDCTFSKSKGLCLLKDSLKVELSVLHKS 665
L DK MLP +DL FSV S + ++ SV+
Sbjct: 596 LVDKRIDMLPMLL--GTDLCSLKPYVDRFAFSVIWELDDSANIV----NVNFMKSVIRSR 649
Query: 666 TRITYEAVDELLDEPTTKPKSGKHEDLKTLFYIAKALRRQRIVDGGAVVFENSSTGIVSL 725
+YE +D+ T + ++ L ++ L+++R+ + GA+ N ++ V +
Sbjct: 650 EAFSYEQAQLRIDDKTQNDELTM--GMRALLKLSVKLKQKRL-EAGAL---NLASPEVKV 703
Query: 726 SPD-DNSELVEVSFKDQIETKSTILVSELMILANSLTAS--YFEENQIPGIYRGYRP--- 779
D + S+ EV K + T S LV E M+LAN A Y Q + R P
Sbjct: 704 HMDSETSDPNEVEIKKLLATNS--LVEEFMLLANISVARKIYDAFPQTAMLRRHAAPPST 761
Query: 780 -LNVVEDATSVPEWVKAKTQENKIISKA-------------DIAKMKS--------FLTS 817
++ + + + + + +K ++ + + ++ S + S
Sbjct: 762 NFEILNEMLNTRKNMSISLESSKALADSLDRCVDPEDPYFNTLVRIMSTRCMMAAQYFYS 821
Query: 818 SFYSSLPTPHDMLGTSHYLTITSPLRRFPDLVNHLQLHRTLKGLPLLYKQSQLDGMVWHI 877
YS H L Y TSP+RR+ D+V H QL + PL + M +
Sbjct: 822 GAYSYPDFRHYGLAVDIYTHFTSPIRRYCDVVAHRQLAGAIGYEPLSLTHRDKNKM--DM 879
Query: 878 LTRDVTLKNASVDAQRYWTLRFLKKEIEDPTKNNWKLQITSLTDNGYAHCVILDKAFAVG 937
+ R++ K+ + ++ + ++ ++ + + +NG V++ K G
Sbjct: 880 ICRNINRKHRNAQFAGRASIEYYVGQVMRNNESTETGYVIKVFNNGIV--VLVPKFGVEG 937
Query: 938 QLKI-NLNKNP 947
+++ NL ++P
Sbjct: 938 LIRLDNLTEDP 948
>Hs19923416 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subunit
Rrp44/Dis3
Length = 958
Score = 55.1 bits (131), Expect = 5e-07
Identities = 80/339 (23%), Positives = 137/339 (39%), Gaps = 50/339 (14%)
Query: 540 ICYC-IDSPDAHEIDDAVSIKSLGGAKYRIYIHVADPASLFPEANEDGTTINSPVLD-IA 597
+C C +D P +IDDA+ + L + +H+AD + N LD +
Sbjct: 473 LCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGN---------ALDQES 523
Query: 598 YQRAFTTYLPDKVFPMLPTTYARSSDLGQFGKPTKAVTFSVDCTFSKSKGLCLLKDSLKV 657
+R T YL +K M+P SS+L + FS C + + +LK K
Sbjct: 524 ARRGTTVYLCEKRIDMVPELL--SSNLCSLKCDVDRLAFS--CIWEMNHNAEILK--TKF 577
Query: 658 ELSVLHKSTRITYEAVDELLDEPTTKPKSGKHEDLKTLFYIAKALRRQRIVDGGAVVFEN 717
SV++ +TY +D + L+ L +AK L+++RI G +
Sbjct: 578 TKSVINSKASLTYAEAQLRID--SANMNDDITTSLRGLNKLAKILKKRRIEKGALTL--- 632
Query: 718 SSTGIVSLSPDDNSELVEVSFKDQIETKSTILVSELMILANSLTA----SYFEENQIPGI 773
SS + + + +++ K+ ET S +V E M+LAN A F E+ +
Sbjct: 633 SSPEVRFHMDSETHDPIDLQTKELRETNS--MVEEFMLLANISVAKKIHEEFSEHALLRK 690
Query: 774 YRGYRPLN---VVEDATSVPEWVKAKTQENKIISKADIAKMKSF--------------LT 816
+ P N +V+ A S +K T ++ + D A+ +F +
Sbjct: 691 HPAPPPSNYEILVKAARSRNLEIKTDTAKS-LAESLDQAESPTFPYLNTLLRILATRCMM 749
Query: 817 SSFYSSLPTPHDM----LGTSHYLTITSPLRRFPDLVNH 851
+ Y +D L + Y TSP+RR+ D++ H
Sbjct: 750 QAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADVIVH 788
>SPCC23B6.06 [J] KOG2102 Exosomal 3'-5' exoribonuclease complex subunit
Rrp44/Dis3
Length = 671
Score = 53.1 bits (126), Expect = 2e-06
Identities = 45/177 (25%), Positives = 77/177 (43%), Gaps = 18/177 (10%)
Query: 533 RTEYKDLICYCIDSPDAHEIDDAVSIKSLGGAKYRIYIHVADPASLFPEANEDGTTINSP 592
R + + L + DS EIDDA+S++ LG + ++IHVA+P S I SP
Sbjct: 503 RVDLRHLKAFAFDSSSTKEIDDAISVEELGMSNSWLHIHVANPTST--------VDIRSP 554
Query: 593 VLDIAYQRAFTTYLPDKVFPMLPTTYARSS-DLGQFGKPTKAVTFS---------VDCTF 642
+ A + T Y P+K+ MLP + L +A+TFS +D
Sbjct: 555 LGTFAERNFQTIYHPNKIVYMLPLNITQKYWSLDSSSTAQRALTFSAKISKNGDILDYKV 614
Query: 643 SKSKGLCLLKDSLKVELSVLHKSTRITYEAVDELLDEPTTKPKSGKHEDLKTLFYIA 699
S ++K + + LH + I + V +DE T + +D+ ++ ++
Sbjct: 615 RPSFISSVIKYTPQQLDKALHSNRSIAKDIVSGPVDEETKGVSNDHMKDILRIYELS 671
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,213,571
Number of Sequences: 60738
Number of extensions: 2693061
Number of successful extensions: 6700
Number of sequences better than 1.0e-05: 15
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 6663
Number of HSP's gapped (non-prelim): 26
length of query: 983
length of database: 30,389,216
effective HSP length: 116
effective length of query: 867
effective length of database: 23,343,608
effective search space: 20238908136
effective search space used: 20238908136
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)