ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1662 good F KOG2938 Nucleotide transport and metabolism Predicted inosine-uridine preferring nucleoside hydrolase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1662 589402 590415 338
(338 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR400w [F] KOG2938 Predicted inosine-uridine preferring nucleos... 399 e-111
SPAC17G8.02 [F] KOG2938 Predicted inosine-uridine preferring nuc... 160 2e-39
SPBC1683.06c [F] KOG2938 Predicted inosine-uridine preferring nu... 112 6e-25
At1g05620 [F] KOG2938 Predicted inosine-uridine preferring nucle... 84 3e-16
At2g36310 [F] KOG2938 Predicted inosine-uridine preferring nucle... 80 4e-15
CE02637 [F] KOG2938 Predicted inosine-uridine preferring nucleos... 76 8e-14
CE21911 [F] KOG2938 Predicted inosine-uridine preferring nucleos... 62 1e-09
7292911 [F] KOG2938 Predicted inosine-uridine preferring nucleos... 60 6e-09
7297954 [F] KOG2938 Predicted inosine-uridine preferring nucleos... 53 7e-07
>YDR400w [F] KOG2938 Predicted inosine-uridine preferring nucleoside
hydrolase
Length = 378
Score = 399 bits (1024), Expect = e-111
Identities = 193/331 (58%), Positives = 247/331 (74%), Gaps = 3/331 (0%)
Query: 5 SVIPIWVDCDPGHDDAVAILLSCFHPSIRLLGISASYGNASPENTLYNTLSLLTAFGKQD 64
S IPIW+DCDPGHDDA+AILL CFHP+ LLGIS +GNA PENT YN SLLTA GK
Sbjct: 42 SKIPIWLDCDPGHDDAIAILLGCFHPAFNLLGISTCFGNAPPENTDYNARSLLTAMGKAQ 101
Query: 65 EVPVYKGAQRPWVRDVAYAPDIHGETGLDGTTLLPKPK-RSFVDADYIKAMENAILANGG 123
+PVYKGAQRPW R+ YAPDIHG +GLDGT+LLPKP + D YI+A+E AILAN G
Sbjct: 102 AIPVYKGAQRPWKREPHYAPDIHGISGLDGTSLLPKPTFEARTDKTYIEAIEEAILANNG 161
Query: 124 NIALVSTGTLTSIATLFKEKPYLKEQVRYISIMGGGLHA-GNRNDNDSAEFNIWADPDAA 182
I+ VSTG LT++AT+F+ KPYLK+ V+YISIMGGGLH GN N N SAEFN+W DPDAA
Sbjct: 162 EISFVSTGALTTLATVFRCKPYLKKSVKYISIMGGGLHGLGNCNPNLSAEFNVWIDPDAA 221
Query: 183 DFILNDEDIKHKCILSPLDLTHTCIATEYIDKTILGD-GSCKLRKLFYELFLFFAKTYKN 241
++I D D+K KCI+ PL+LTH IAT +++ I + + KLR+LF ELF FFA TYK+
Sbjct: 222 NYIFRDPDVKDKCIVVPLNLTHKAIATYKVNEMIYNEKNNSKLRELFLELFQFFAHTYKD 281
Query: 242 KQGFEAGPPVHDPVTLMPLLYLYGHISNDILRFKYGRFDLSIDKNQDSINYGRTIVTQEY 301
QGFE+GPP+HDPV LMPLL YG + + F+Y R D+S + + N G+ I+ +EY
Sbjct: 282 MQGFESGPPIHDPVALMPLLEFYGWDPSSAVGFRYKRMDISCIDDVFNENSGKIIIEKEY 341
Query: 302 PSDSNFGLMVGLQINVDFFWNQVLNAIDVAE 332
P+DS+ G ++GL +N+ +FW+Q+ A++ A+
Sbjct: 342 PNDSDVGTIIGLDLNIQYFWDQIFEALNRAD 372
>SPAC17G8.02 [F] KOG2938 Predicted inosine-uridine preferring nucleoside
hydrolase
Length = 330
Score = 160 bits (406), Expect = 2e-39
Identities = 105/326 (32%), Positives = 159/326 (48%), Gaps = 24/326 (7%)
Query: 9 IWVDCDPGHDDAVAILLSCFHPSIRLLGISASYGNASPENTLYNTLSLLTAFGKQDEVPV 68
IW+DCDPGHDD VA+ L+ ++LG+S +GN + E T N L+++ + +V V
Sbjct: 19 IWIDCDPGHDDVVALTLAACAGHCKILGVSTVHGNTTLEFTTKNALAVMELLNQ--DVDV 76
Query: 69 YKGAQRPWVRDVAYAPDIHGETGLDGTTLLPKPKRSFVDADYIKAMENAILANGGNIALV 128
+ GA +P +R+ A+A IHG GL G +LLP + D + AM I + LV
Sbjct: 77 HAGAAKPLMRESAFATHIHGTNGLAGISLLPDYPKKKATPDAVFAMYTTISNYPEPVTLV 136
Query: 129 STGTLTSIATLFKEKPYLKEQVRYISIMGGGLHAGNRNDNDSAEFNIWADPDAADFILND 188
+TG LT+IA L P + + + MGG G N AEFN++ADP+AA +L
Sbjct: 137 ATGPLTNIALLLATYPSVTDNIERFIFMGGSTGIG--NITSQAEFNVYADPEAARLVLET 194
Query: 189 EDIKHKCILSPLDLTHTCIATEYIDKTILGDGSCKLRKLFYELFLFFAKTYKNKQGFEAG 248
+ + K + PLD+TH + I + +L S EL F +TY+N G G
Sbjct: 195 KSLIGKLFMVPLDVTHKVLLDANIIQ-LLRQHSNPFSSTLVELMTVFQQTYENVYGIRNG 253
Query: 249 PPVHDPVTLMPLLYLYGHISNDILRFKYGRFDLSIDKNQDSINYGRTIV-----TQEYPS 303
PVHD + L+ S + + + DS+ GRT+ +YP+
Sbjct: 254 VPVHDVCAVALALWPSLWTSR----------SMYVTVSLDSLTLGRTVCDVWSQQNQYPA 303
Query: 304 DSNFGLMVGLQINVDFFWNQVLNAID 329
+ + V L+ +V FW + ID
Sbjct: 304 N----VHVVLEADVSLFWETFIGVID 325
>SPBC1683.06c [F] KOG2938 Predicted inosine-uridine preferring nucleoside
hydrolase
Length = 310
Score = 112 bits (281), Expect = 6e-25
Identities = 82/255 (32%), Positives = 125/255 (48%), Gaps = 11/255 (4%)
Query: 9 IWVDCDPGHDDAVAILLSCFHPSIRLLGISASYGNASPENTLYNTLSLLTAFGKQDEVPV 68
I +D DPG DDA+ LL+ P I LLG++ GN T N L +L G+ D +PV
Sbjct: 3 IIIDTDPGQDDAITALLAIASPEIELLGVTTVAGNVPVSMTTRNALQMLDLAGRPD-IPV 61
Query: 69 YKGAQRPWVRDVAYAPDIHGETGLDGTTLLPKPKRSFVDADYIKAMENAILAN-GGNIAL 127
Y G+ +P +R A +HG +G +G +LP P R + + + + + N G I +
Sbjct: 62 YAGSNKPLLRAPITATHVHGASGFEG-AVLPPPSRKENEGHAVDFIIDTLRNNEPGTITI 120
Query: 128 VSTGTLTSIATLFKEKPYLKEQVRYISIMGGGLHAGNRNDNDSAEFNIWADPDAADFILN 187
+ G LT+IA + P + ++ + I +M G N +AEFNI+ DP AA +L+
Sbjct: 121 CTIGPLTNIALALNKAPEVIQRAKQIVMMAGAFSEVG-NITPAAEFNIYVDPHAAQMVLS 179
Query: 188 DEDIKHKCILSPLDLTHTCIATEYIDKTILGDGSCKLR-KLFYELFLFFAKTYKNKQGFE 246
++ PLD+TH + K I + R +L K Y+ K+
Sbjct: 180 S---GIPIVMMPLDITHQLHTSA---KRIARMEALPNRVGPVVAAWLRMEKAYEAKKYGT 233
Query: 247 AGPPVHDPVTLMPLL 261
G P+HDP T+M LL
Sbjct: 234 DGGPLHDPNTVMWLL 248
>At1g05620 [F] KOG2938 Predicted inosine-uridine preferring nucleoside
hydrolase
Length = 358
Score = 84.0 bits (206), Expect = 3e-16
Identities = 77/281 (27%), Positives = 125/281 (44%), Gaps = 49/281 (17%)
Query: 18 DDAVAILLSCFHPSIRLLGISASYGNASPENTLYNTLSLLTAFGKQDEVPVYKGAQRPWV 77
DDA+AI ++ P + ++G++ +GN N L LL G+ D +PV +G + ++
Sbjct: 33 DDAMAIFVALNSPEVDVIGLTTIFGNVYTTLATRNALHLLEVAGRTD-IPVAEGTHKTFL 91
Query: 78 RD--VAYAPDIHGETGLDGTTLLPKPKRSFVDADYIKAMENAILANGGNIALVSTGTLTS 135
D + A +HG+ GL G P PK ++ + + G I +V+ G LT+
Sbjct: 92 NDTKLRIADFVHGKDGL-GNQNFPPPKGKPIEKSGPEFLVEQAKLCPGEITVVALGPLTN 150
Query: 136 IATLFKEKPYLKEQVRYISIMGGGLHAGNRNDNDSAEFNIWADPDAADFILN-DEDIKHK 194
+A + P + V I ++GG A N N N ++E NI+ DP+AAD + DI
Sbjct: 151 LALAVQLDPEFSKNVGQIVLLGGAF-AVNGNVNPASEANIFGDPEAADIVFTCGADI--- 206
Query: 195 CILSPLDLTHTCIATEY----------------------IDKTILGDGS-----CKLRKL 227
I +++TH I TE+ DK G CK+ +
Sbjct: 207 -IAVGINVTHQVIMTEHNLVKQSFLMAFFPVFLLDLADDKDKLASSKGKLAQYLCKILDV 265
Query: 228 FYELFLFFAKTYKNKQGFEAGPPVHDPVTL----MPLLYLY 264
+Y+ L Y+ K G +HDP T+ +P L+ Y
Sbjct: 266 YYDYHL---TAYEIK-----GVYLHDPATILAAFLPSLFTY 298
>At2g36310 [F] KOG2938 Predicted inosine-uridine preferring nucleoside
hydrolase
Length = 305
Score = 80.1 bits (196), Expect = 4e-15
Identities = 51/166 (30%), Positives = 85/166 (50%), Gaps = 4/166 (2%)
Query: 21 VAILLSCFHPSIRLLGISASYGNASPENTLYNTLSLLTAFGKQDEVPVYKGAQRPWVRDV 80
+AIL++ P + +LG++ +GN S ++ N L L G D VPV +G+ P +
Sbjct: 1 MAILMAFQTPELEILGLTTVFGNVSTQDATRNALLLCEIAGFPD-VPVAEGSSEPLKGGI 59
Query: 81 AYAPD-IHGETGLDGTTLLPKPKRSFVDADYIKAMENAILANGGNIALVSTGTLTSIATL 139
D +HG+ GL G LP P R + + ++ + G + +++ G LT++A
Sbjct: 60 PRVADFVHGKNGL-GDVSLPPPSRKKSEKSAAEFLDEKVEEYPGEVTILALGPLTNLALA 118
Query: 140 FKEKPYLKEQVRYISIMGGGLHAGNRNDNDSAEFNIWADPDAADFI 185
K +V+ I I+GG + N N +AE NI+ DP+AAD +
Sbjct: 119 IKRDSSFASKVKKIVILGGAFFSLG-NVNPAAEANIYGDPEAADVV 163
>CE02637 [F] KOG2938 Predicted inosine-uridine preferring nucleoside
hydrolase
Length = 452
Score = 75.9 bits (185), Expect = 8e-14
Identities = 54/189 (28%), Positives = 94/189 (49%), Gaps = 10/189 (5%)
Query: 7 IPIWVDCDPGHDDAVAILLSCFHPSIRLLGISASYGNASPENTLYNTLSLLTAFGKQDEV 66
+ + +D D +DD + ++ + ++ ++ I+ +G + + N LL A GK + V
Sbjct: 101 VKLIIDTDGVYDDIRGLTIALTNQNVEVIAITTVHGGVTANQSAANVARLLRAIGKHN-V 159
Query: 67 PVYKGAQRPWVRD--VAYAPDIHGETGLDGTT-----LLPKPKRSFVDADYIKAMENAIL 119
PV+ GAQ V + ++ G G+ G LP S + + A+ N +
Sbjct: 160 PVFIGAQDSLVPKGPIQVWEELFGSDGIGGVPDVEPKTLPSDFNSAQVGNAVDAIIN-LT 218
Query: 120 ANGGNIALVSTGTLTSIATLFKEKPYLKEQVRYISIMGGG-LHAGNRNDNDSAEFNIWAD 178
+ +I LV G LT+IA ++ P + ++V+ + IMGG L GN N +AEFN D
Sbjct: 219 KSTKDIILVGLGPLTNIAMAIRKDPDISKRVKQVVIMGGNYLGVGNTQFNSTAEFNFLMD 278
Query: 179 PDAADFILN 187
P+AA +L+
Sbjct: 279 PEAAHIVLS 287
>CE21911 [F] KOG2938 Predicted inosine-uridine preferring nucleoside
hydrolase
Length = 338
Score = 62.0 bits (149), Expect = 1e-09
Identities = 53/187 (28%), Positives = 85/187 (45%), Gaps = 9/187 (4%)
Query: 7 IPIWVDCDPGHDDAVAILLSCFHPSIRLLGISASYGNASPENTLYNTLSLLTAFGKQDEV 66
+ + +D D DD AI L+ HP +L +A +G + + N + A + +
Sbjct: 6 VKLVIDSDGVSDDVRAISLALQHPKAEILAFTAVHGCVTVDQACANIKRTIRA-NDRSNI 64
Query: 67 PVYKGAQRPWV---RDVAYAPDIHGETGL-DGTTLLPKPKRSFVDAD--YIKAMENAILA 120
PVYKGA + + +D + D G G+ D PK +RS + + + IL
Sbjct: 65 PVYKGAAKSILSLPKDDTVS-DFFGIDGIGDKPEEFPKVERSDFEGEGKHASLALIDILR 123
Query: 121 NGGNIALVSTGTLTSIATLFKEKPYLKEQVRYISIMGGGLHA-GNRNDNDSAEFNIWADP 179
+ LV+ G LT++A + + IMGG +A GN + SAE+N DP
Sbjct: 124 ENRDATLVTIGPLTNVAIALQLCEEFSTYPSRLVIMGGNYYAVGNVDGGSSAEYNFHGDP 183
Query: 180 DAADFIL 186
+AA +L
Sbjct: 184 EAASIVL 190
>7292911 [F] KOG2938 Predicted inosine-uridine preferring nucleoside
hydrolase
Length = 362
Score = 59.7 bits (143), Expect = 6e-09
Identities = 57/185 (30%), Positives = 85/185 (45%), Gaps = 11/185 (5%)
Query: 11 VDCDPGHDDAVAILL---SCFHPSIRLLGISA-SYGNASPENTLYNTLSLLTAFGKQDEV 66
+DCD G DDA A+LL + I LL I+ GN S EN N +L A K+ ++
Sbjct: 29 LDCDGGSDDAWALLLLLHAAKSHGIHLLAITTMGCGNTSRENAARNMRRILDAC-KRTDI 87
Query: 67 PVYKGAQRPWVRDVAYAPD-IHGETGLDG--TTLLPKPKRSFVDADY-IKAMENAILANG 122
P+Y GA + + HG G T V A++ + A+ + +
Sbjct: 88 PIYLGAVDALIPSLEDEKKYFHGRDGFGDCLTDDCALQLEDIVQAEHAVTAIHDLCRSRP 147
Query: 123 GNIALVSTGTLTSIATLFKEK-PYLKEQVRYISIMGGGLHAGNRNDNDSAEFNIWADPDA 181
I + + G LT++A + P R + IMGG + G N + SAEFN +DP+A
Sbjct: 148 KQITIFAVGPLTNLALGYTMYGPEFGNNFRDLFIMGGN-YQGVGNSSRSAEFNFHSDPEA 206
Query: 182 ADFIL 186
A +L
Sbjct: 207 AHTVL 211
>7297954 [F] KOG2938 Predicted inosine-uridine preferring nucleoside
hydrolase
Length = 355
Score = 52.8 bits (125), Expect = 7e-07
Identities = 58/202 (28%), Positives = 87/202 (42%), Gaps = 19/202 (9%)
Query: 12 DCDPGHDDA--VAILLSCFHPSI------RLLGISASYGNASPENTLYNTLSLLTAFGKQ 63
DCD G DDA +A+LL S+ +L+ I+ GN N N L +L ++
Sbjct: 15 DCDIGTDDAWALALLLRGEQLSLASGRRYKLIAITCVQGNTDVVNGAQNALKILRLLERR 74
Query: 64 DEVPVYKGAQRPWV-RDVAYAPDIHGETGLDGTTLLPKP---KRSFVDADYIKAMENAIL 119
D VPV++G P V R HG GL+ P + + AM +
Sbjct: 75 D-VPVFRGCANPIVTRTWLDISRFHGTDGLNDIGGYPDVSDLQEQLQQEHAVNAMYRLVC 133
Query: 120 ANGGNIALVSTGTLTSIATLFK--EKPYLKEQVRYISIMGGGLHAGNRNDNDSAEFNIWA 177
+ + G LT+ A+ +L +++ I IMGG ++ G N AEFN
Sbjct: 134 QYPKQVDFLLCGPLTNFASCINLYGDDFL-DKIGGIFIMGGNIY-GRGNIMKCAEFNFMM 191
Query: 178 DPDAADFILNDEDIKHKCILSP 199
DP+AA L E +K ++ P
Sbjct: 192 DPEAAHTTL--ERLKVPAVILP 211
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.140 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,283,753
Number of Sequences: 60738
Number of extensions: 987254
Number of successful extensions: 1833
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1816
Number of HSP's gapped (non-prelim): 9
length of query: 338
length of database: 30,389,216
effective HSP length: 107
effective length of query: 231
effective length of database: 23,890,250
effective search space: 5518647750
effective search space used: 5518647750
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)