ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1702 check: MH O KOG1867 Posttranslational modification, protein turnover, chaperones Ubiquitin-specific protease
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1702 605684 604347 -446
(446 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR223w [O] KOG1867 Ubiquitin-specific protease 500 e-141
SPAC13A11.04c [O] KOG1867 Ubiquitin-specific protease 239 6e-63
7293885 [O] KOG1867 Ubiquitin-specific protease 212 8e-55
Hs22065367 [O] KOG1867 Ubiquitin-specific protease 211 1e-54
Hs22055583 [O] KOG1867 Ubiquitin-specific protease 189 9e-48
At5g10790 [O] KOG1867 Ubiquitin-specific protease 183 5e-46
SPCC1682.12c [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 178 2e-44
Hs13435157 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 159 6e-39
Hs20540195 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 158 2e-38
7295432 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 155 1e-37
7300711 [O] KOG1868 Ubiquitin C-terminal hydrolase 146 5e-35
Hs22044530 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 146 7e-35
Hs22044559 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 145 9e-35
Hs22044551 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 145 9e-35
Hs22044543 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 145 9e-35
Hs22044565 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 145 1e-34
Hs22044547 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 145 1e-34
Hs22044539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 145 2e-34
At3g14400 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 144 2e-34
Hs22044534 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 143 5e-34
Hs18557591 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 142 8e-34
At5g46740 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 142 1e-33
Hs22044537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 141 2e-33
Hs22044541 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 140 4e-33
Hs5730110 [O] KOG1867 Ubiquitin-specific protease 139 1e-32
Hs22044528 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 138 2e-32
HsM19923759 [O] KOG1868 Ubiquitin C-terminal hydrolase 137 4e-32
Hs21361712 [O] KOG1868 Ubiquitin C-terminal hydrolase 137 4e-32
At1g17110 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 135 2e-31
At4g31670 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 134 2e-31
Hs4827054 [O] KOG1868 Ubiquitin C-terminal hydrolase 132 1e-30
7295645 [O] KOG1868 Ubiquitin C-terminal hydrolase 132 1e-30
At4g17890_2 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 130 4e-30
At2g24640 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 129 9e-30
At4g24560 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 128 2e-29
Hs22044555 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 127 3e-29
At5g65450 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 125 2e-28
At2g22310 [O] KOG1864 Ubiquitin-specific protease 122 8e-28
Hs20548613 [O] KOG1864 Ubiquitin-specific protease 119 7e-27
At5g57990 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 119 7e-27
HsM7706755 [O] KOG1868 Ubiquitin C-terminal hydrolase 118 2e-26
Hs12383078 [O] KOG1864 Ubiquitin-specific protease 118 2e-26
YDR069c [O] KOG1868 Ubiquitin C-terminal hydrolase 117 3e-26
Hs6912742 [O] KOG1868 Ubiquitin C-terminal hydrolase 117 3e-26
At4g39910 [O] KOG1864 Ubiquitin-specific protease 117 3e-26
YNL186w [O] KOG1870 Ubiquitin C-terminal hydrolase 112 1e-24
YER144c [O] KOG1868 Ubiquitin C-terminal hydrolase 112 1e-24
CE26210 [O] KOG1868 Ubiquitin C-terminal hydrolase 111 2e-24
CE23922 [O] KOG1864 Ubiquitin-specific protease 110 4e-24
CE11978 [O] KOG1870 Ubiquitin C-terminal hydrolase 109 9e-24
SPBC713.02c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 107 4e-23
Hs21265129 [O] KOG1868 Ubiquitin C-terminal hydrolase 104 2e-22
7292738 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 103 4e-22
SPCC188.08c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 102 2e-21
At5g06600 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 102 2e-21
At3g11910 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 102 2e-21
Hs18860907_1 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 102 2e-21
Hs20472401 [O] KOG1870 Ubiquitin C-terminal hydrolase 100 4e-21
SPBC1703.12 [O] KOG1864 Ubiquitin-specific protease 100 7e-21
HsM18874088 [O] KOG1870 Ubiquitin C-terminal hydrolase 100 7e-21
Hs22043041 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 100 7e-21
Hs21489975 [O] KOG1870 Ubiquitin C-terminal hydrolase 100 7e-21
Hs5730108 [O] KOG1870 Ubiquitin C-terminal hydrolase 97 4e-20
Hs4759290 [O] KOG1870 Ubiquitin C-terminal hydrolase 97 5e-20
SPCC1494.05c [O] KOG1870 Ubiquitin C-terminal hydrolase 97 6e-20
CE23923 [O] KOG1864 Ubiquitin-specific protease 96 1e-19
YMR304w [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 95 2e-19
Hs14149627 [O] KOG1870 Ubiquitin C-terminal hydrolase 94 5e-19
YJL197w [O] KOG1870 Ubiquitin C-terminal hydrolase 93 7e-19
7300926 [O] KOG1864 Ubiquitin-specific protease 93 9e-19
Hs4507853 [O] KOG1870 Ubiquitin C-terminal hydrolase 92 2e-18
Hs4507857 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 91 3e-18
7302097 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 91 3e-18
Hs14149817 [O] KOG1867 Ubiquitin-specific protease 91 5e-18
At4g10590 [O] KOG1870 Ubiquitin C-terminal hydrolase 90 8e-18
YER098w [O] KOG1864 Ubiquitin-specific protease 89 1e-17
CE26241 [O] KOG1867 Ubiquitin-specific protease 89 1e-17
YBL067c [O] KOG1864 Ubiquitin-specific protease 89 2e-17
SPBC18H10.08c [O] KOG1868 Ubiquitin C-terminal hydrolase 89 2e-17
7303210 [O] KOG1870 Ubiquitin C-terminal hydrolase 89 2e-17
Hs22063256 [O] KOG1870 Ubiquitin C-terminal hydrolase 88 2e-17
At4g10570 [O] KOG1870 Ubiquitin C-terminal hydrolase 88 3e-17
Hs22068900 [O] KOG1870 Ubiquitin C-terminal hydrolase 87 4e-17
Hs11641425 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 86 9e-17
Hs11641423 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 86 9e-17
At3g49600_2 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 86 9e-17
Hs20532433 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 86 1e-16
7291841 [O] KOG1870 Ubiquitin C-terminal hydrolase 86 1e-16
Hs4759296 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 85 2e-16
At2g40930 [O] KOG1870 Ubiquitin C-terminal hydrolase 83 7e-16
ECU03g0580 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 83 9e-16
CE29636 [O] KOG1870 Ubiquitin C-terminal hydrolase 83 9e-16
CE29635 [O] KOG1870 Ubiquitin C-terminal hydrolase 83 9e-16
At1g32850 [O] KOG1870 Ubiquitin C-terminal hydrolase 82 2e-15
CE16183 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 81 3e-15
CE16182 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 81 3e-15
Hs22044589 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 81 4e-15
CE03146 [O] KOG1870 Ubiquitin C-terminal hydrolase 80 8e-15
SPBC19C2.04c [O] KOG1867 Ubiquitin-specific protease 79 1e-14
SPCC16A11.12c [O] KOG1870 Ubiquitin C-terminal hydrolase 78 3e-14
Hs10190742 [O] KOG1868 Ubiquitin C-terminal hydrolase 77 4e-14
7295436 [O] KOG4598 Putative ubiquitin-specific protease 77 5e-14
Hs22045513 [O] KOG1868 Ubiquitin C-terminal hydrolase 76 1e-13
7292013_2 [O] KOG1871 Ubiquitin-specific protease 75 2e-13
SPBP8B7.21 [O] KOG1871 Ubiquitin-specific protease 74 3e-13
SPBC6B1.06c [O] KOG0944 Ubiquitin-specific protease UBP14 74 4e-13
Hs5454156 [O] KOG1873 Ubiquitin-specific protease 73 7e-13
7303452 [O] KOG1864 Ubiquitin-specific protease 73 7e-13
Hs22067085 [O] KOG1871 Ubiquitin-specific protease 73 1e-12
Hs21361749 [O] KOG1867 Ubiquitin-specific protease 73 1e-12
At1g04860 [O] KOG1873 Ubiquitin-specific protease 72 2e-12
ECU07g0410 [O] KOG1868 Ubiquitin C-terminal hydrolase 70 8e-12
CE19500 [O] KOG1870 Ubiquitin C-terminal hydrolase 70 8e-12
Hs13994268 [O] KOG1868 Ubiquitin C-terminal hydrolase 67 4e-11
Hs22047537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 66 9e-11
Hs14776897 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 66 9e-11
Hs22047539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 65 2e-10
At2g32780 [O] KOG1873 Ubiquitin-specific protease 65 3e-10
Hs14777500 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 64 3e-10
Hs8394519 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 63 8e-10
Hs22056581 [O] KOG1868 Ubiquitin C-terminal hydrolase 62 2e-09
CE27053 [O] KOG1864 Ubiquitin-specific protease 62 2e-09
YBR058c [O] KOG0944 Ubiquitin-specific protease UBP14 61 3e-09
CE13299 [O] KOG4598 Putative ubiquitin-specific protease 61 4e-09
CE09811 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 60 5e-09
ECU06g0910 [O] KOG1870 Ubiquitin C-terminal hydrolase 57 7e-08
At3g21280 [O] KOG1872 Ubiquitin-specific protease 56 9e-08
Hs20483065 [O] KOG1864 Ubiquitin-specific protease 54 6e-07
7293731 [O] KOG1870 Ubiquitin C-terminal hydrolase 54 6e-07
YER151c [O] KOG1871 Ubiquitin-specific protease 53 1e-06
Hs14211903 [O] KOG1870 Ubiquitin C-terminal hydrolase 52 2e-06
YIL156w [O] KOG1868 Ubiquitin C-terminal hydrolase 51 3e-06
CE15678 [O] KOG1867 Ubiquitin-specific protease 51 3e-06
Hs14249724 [O] KOG1873 Ubiquitin-specific protease 50 7e-06
CE13964 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 50 9e-06
>YMR223w [O] KOG1867 Ubiquitin-specific protease
Length = 471
Score = 500 bits (1287), Expect = e-141
Identities = 232/466 (49%), Positives = 323/466 (68%), Gaps = 21/466 (4%)
Query: 2 VCPHMNQVVSNQKLGDAVLKECETVRYLLRHADFKNRTMRTMRCMDCGEISCGSTFICLQ 61
+CPH+ QV N+K D VLK C RY+L H+ K + + TM+C C EI+ G+TF+CLQ
Sbjct: 3 ICPHIQQVFQNEKSKDGVLKTCNAARYILNHSVPKEKFLNTMKCGTCHEINSGATFMCLQ 62
Query: 62 CGFCGCWNNNHFLDHSQKLGHIFGVNSSNGLVFCFRCGDFMA--DLVAE-IPASQWDTVM 118
CGFCGCWN++HFL HS+++GHIFG+NS+NGL+FCF+C D++ DL+ + I A WD V
Sbjct: 63 CGFCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDYIGNIDLINDAILAKYWDDVC 122
Query: 119 EKTELPASLHRDGLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKC 178
KT +P+ RDGL GL+NMGSTCFMSSI+Q +IHNPYF+ +S H NNC ++S KC
Sbjct: 123 TKTMVPSMERRDGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKC 182
Query: 179 VSCALDEIACDFYG-----NGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYW 233
SCALD+I + YG + S++ GF+ LL+ +W IN +L G SQQDAHE+W
Sbjct: 183 FSCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFW 242
Query: 234 QFLLNQLHTDH------ARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQC-GFSKTTIDP 286
QF++NQ+H + A+ + C+CI H +F+G L++++ C C SKTTIDP
Sbjct: 243 QFIINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDP 302
Query: 287 IMDLSLEIKNNPKLEDCLDHFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQL 346
+DLSL+IK+ KL +CLD F ++E L DF+Y C C Q +KQL +HK P+VLV+QL
Sbjct: 303 FLDLSLDIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQL 362
Query: 347 KRFEHQLNGQSAKLNDRVQFPLHLNLKPHLF------QIEDEYIPNIAYDLLNVVSHQGT 400
KRFEH LNG + KL+D ++FP +LN+K + E+ +P+I Y+L+ +VSH+GT
Sbjct: 363 KRFEHLLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGT 422
Query: 401 VDQGHYTTVSKTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFYIIR 446
V++GHY K GQWFKFNDS+V+S+++E+VL++QAYLLFY IR
Sbjct: 423 VNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIR 468
>SPAC13A11.04c [O] KOG1867 Ubiquitin-specific protease
Length = 449
Score = 239 bits (610), Expect = 6e-63
Identities = 147/420 (35%), Positives = 220/420 (52%), Gaps = 44/420 (10%)
Query: 44 RCMDCGEISCGSTFICLQCGFCGCWNNNHFLDHSQKLGHIFGVNSSNGLVFCFRCGDFMA 103
RC C I+ S CL C GC +H +H+ + H+ GV+ NG +CF C D++
Sbjct: 37 RCSTCKRINKRS-IRCLSCHSVGCLWGHHGEEHAMEHTHMIGVDVKNGHTYCFGCQDYVY 95
Query: 104 DLVAE--------IPASQWD--TVMEK----------TELPASLHRDGLQGLVNMGSTCF 143
E I A Q D + EK + P GL+G+ N+G+TCF
Sbjct: 96 QTELETLRFKIKNIKAWQSDHKRLPEKYNQMVCLEAYRKYPPVCATAGLRGIQNLGATCF 155
Query: 144 MSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGNGPGTGKSSSV 203
MS I+Q+I+HNP V +L + D K T C++CA+D++ Y + K+ S
Sbjct: 156 MSVILQSILHNP-LVRNLFFSGFHTSTDCKRPT-CMTCAIDDMFSSIYNS-----KNKST 208
Query: 204 SKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGSSKAPDCQCITHRI 263
G +L+ W ++ L G SQQD HE++ +LL+Q+HT+ G + C C HRI
Sbjct: 209 FYGPTAVLNLMWKLSKSLCGYSQQDGHEFFVYLLDQMHTES----GGGTSMPCTCPIHRI 264
Query: 264 FQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQREETLTDFHYECQSC 323
F G LKN + C C + +DP+MD+SL+I N P L+ CL+ F +E + Y C SC
Sbjct: 265 FSGSLKNVVTCLDCKKERVAVDPLMDISLDI-NEPTLQGCLERFVSKEKV---QYSCHSC 320
Query: 324 KQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEY 383
++ +KQL K P + +QLKRFE S K++ +V +P L ++ + Q
Sbjct: 321 -GSKNAIKQLVFDKLPPTICMQLKRFEQNNFAMSTKIDKQVSYPAFLRMRYNFNQ----- 374
Query: 384 IPNIAYDLLNVVSHQGTVDQGHYTTVSKTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
++ Y L +VV H+GT+D GHY + ++ QWF +D+ + V E +VL QAYLLFY
Sbjct: 375 -DDVDYQLYSVVCHKGTLDTGHYIAYTYYQN-QWFLLDDTTIVEVKESEVLNSQAYLLFY 432
>7293885 [O] KOG1867 Ubiquitin-specific protease
Length = 735
Score = 212 bits (540), Expect = 8e-55
Identities = 142/468 (30%), Positives = 217/468 (46%), Gaps = 73/468 (15%)
Query: 37 NRTMRTMRCMDCGEISCGS----TFICLQCGFCGCWNNNHFLDHSQKLGHIFGVNSSNGL 92
NR R + + C CGS + CL C + GC H H + H + S+G
Sbjct: 272 NRDARERKAIHCNCFECGSYGIQLYACLHCIYFGC-RGAHITSHLRSKKHNVALELSHGT 330
Query: 93 VFCFRCGDFM-----------------ADLVAEIPASQWDTVMEKTELPASLHRD----- 130
++C+ C DF+ DL I W ++T L + R
Sbjct: 331 LYCYACRDFIYDARSREYALINRKLEAKDLQKSIGWVPWVPTTKETNLLLANARRRLVRP 390
Query: 131 ----GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEI 186
GL+GL+N+G+TCFM+ I+Q ++H P + +S +H +C KS KC+ C + +
Sbjct: 391 NQTIGLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRH--DCGSKSSHKCLVCEVSRL 448
Query: 187 ACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLH----- 241
+FY +G S +S LL W+ HL G QQDAHE++ L+ LH
Sbjct: 449 FQEFY-----SGSRSPLS--LHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVK 501
Query: 242 -----------------TDHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTI 284
T+ + S C CI +IF G L++ + C C TT
Sbjct: 502 AKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTY 561
Query: 285 DPIMDLSLEIKNN-------PK-LEDCLDHFQREETL-TDFHYECQSCKQNQGVVKQLTL 335
DP D+SL++ PK L DCL+ + R E L + +C +CK Q KQ +L
Sbjct: 562 DPFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSL 621
Query: 336 HKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVV 395
P+V+ LKRFEH K++ +QFP+ ++ P + + ++ Y + + L VV
Sbjct: 622 RTLPSVVSFHLKRFEHSAL-IDRKISSFIQFPVEFDMTPFMSEKKNAY-GDFRFSLYAVV 679
Query: 396 SHQGTVDQGHYTTVSKTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
+H GT+D GHYT + + W K +D V+T + +QVL+ + YLLFY
Sbjct: 680 NHVGTIDTGHYTAYVRHQKDTWVKCDDHVITMASLKQVLDSEGYLLFY 727
>Hs22065367 [O] KOG1867 Ubiquitin-specific protease
Length = 525
Score = 211 bits (538), Expect = 1e-54
Identities = 143/478 (29%), Positives = 214/478 (43%), Gaps = 78/478 (16%)
Query: 33 ADFKNRTMRTMRCMDCGEISCGSTFICLQCGFCGCWNNNHFLDHSQKLGHIFGVNSSNGL 92
A+ + R ++ C CG + CL C F GC+ H +H++ H ++ G
Sbjct: 51 AEARKRKAKSCICHVCG-VHLNRLHSCLYCVFFGCFTKKHIHEHAKAKRHNLAIDLMYGG 109
Query: 93 VFCFRCGDFMADLVAEIPA-----------------SQWDTVMEKTELP---------AS 126
++CF C D++ D EI A S W+ + EL S
Sbjct: 110 IYCFLCQDYIYDKDMEIIAKEEQRKAWKMQGVGEKFSTWEPTKRELELLKHNPKRRKITS 169
Query: 127 LHRDGLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEI 186
GL+GL+N+G+TCFM+ I+Q + H P + LS +H C+++S + C+ C + +
Sbjct: 170 NCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRH--RCEMQSPSSCLVCEMSSL 227
Query: 187 ACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHAR 246
+FY +S + ++L+ W HL G QQDAHE+ L+ LH
Sbjct: 228 FQEFYSGH----RSPHIPYKLLHLV---WTHARHLAGYEQQDAHEFLIAALDVLHRHCKG 280
Query: 247 VFGSSKAPD---CQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLE---------- 293
KA + C CI +IF G L++ + C C TTIDP D+SL+
Sbjct: 281 DDNGKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWP 340
Query: 294 ---------------IKNNPKLEDCLDHFQREETL-TDFHYECQSCKQNQGVVKQLTLHK 337
+ L DCL F R E L + +C C Q KQLT+ K
Sbjct: 341 LSPGSEGNVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKK 400
Query: 338 APNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLF------------QIEDEYIP 385
P V LKRFEH + K+ V FPL L++ P + Q D
Sbjct: 401 LPIVACFHLKRFEHSAKLRR-KITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLNN 459
Query: 386 NIAYDLLNVVSHQGTVDQGHYTTVSKTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
+ Y L VV+HQGT++ GHYT+ + QWFK +D+++T + + VL+ + YLLFY
Sbjct: 460 DNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFY 517
>Hs22055583 [O] KOG1867 Ubiquitin-specific protease
Length = 800
Score = 189 bits (479), Expect = 9e-48
Identities = 118/365 (32%), Positives = 179/365 (48%), Gaps = 50/365 (13%)
Query: 119 EKTELPASLHRDGLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKC 178
+K S++ GL+GL+N+G+TCFM+ I+Q + H P + LS KH C + S + C
Sbjct: 438 KKKRRKKSVYTVGLRGLINLGNTCFMNCIVQALTHIPLLKDFFLSDKH--KCIMTSPSLC 495
Query: 179 VSCALDEIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLN 238
+ C + + Y ++ + ++L+ W HL G QQDAHE+ +L+
Sbjct: 496 LVCEMSSLFHAMYSGS----RTPHIPYKLLHLI---WIHAEHLAGYRQQDAHEFLIAILD 548
Query: 239 QLHTDHARVFGSSKAPD---CQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIK 295
LH G +A + C CI +IF G L++ + C C TTIDP D+SL++
Sbjct: 549 VLHRHSKDDSGGQEANNPNCCNCIIDQIFTGGLQSDVTCQACHSVSTTIDPCWDISLDLP 608
Query: 296 NN-------------------------PKLEDCLDHFQREETL-TDFHYECQSCKQNQGV 329
+ P L DCL F R E L + +C SC+ Q
Sbjct: 609 GSCATFDSQNPERADSTVSRDDHIPGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQSYQES 668
Query: 330 VKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLFQIED-------- 381
KQLT+ K P V LKRFEH + Q K+N + FPL L++ P L ++
Sbjct: 669 TKQLTMKKLPIVACFHLKRFEH-VGKQRRKINTFISFPLELDMTPFLASTKESRMKEGQP 727
Query: 382 --EYIPNI-AYDLLNVVSHQGTVDQGHYTTVSKTEDGQWFKFNDSVVTSVTEEQVLEQQA 438
+ +PN Y L V++H GT++ GHYT+ + + QWF +D+++T T E +L +
Sbjct: 728 PTDCVPNENKYSLFAVINHHGTLESGHYTSFIRQQKDQWFSCDDAIITKATIEDLLYSEG 787
Query: 439 YLLFY 443
YLLFY
Sbjct: 788 YLLFY 792
>At5g10790 [O] KOG1867 Ubiquitin-specific protease
Length = 557
Score = 183 bits (464), Expect = 5e-46
Identities = 145/496 (29%), Positives = 230/496 (46%), Gaps = 118/496 (23%)
Query: 44 RCMDCGEISCGSTFICLQCGFCGCWNNNHFLDHSQ-KLGHIFGVNSSNGLVFCFRCGDFM 102
RC C + +ICL C C ++H L H+Q GH ++ ++C C D +
Sbjct: 55 RCSYCS-VYQKRLYICLICRSISC--SSHILLHTQLNKGHDIAIDVERSELYCCACIDQV 111
Query: 103 ADLVAEIPASQWDTVM------------------------EKTELPASL---------HR 129
D S++D V+ +K L + L R
Sbjct: 112 YD-------SEFDEVVVSKQLFGLGMSVKSGADVVAVRSNKKRRLDSQLIIGSNFLVSPR 164
Query: 130 D---------GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNN-CDIKS-GTKC 178
D GL+GL N+GSTCFM++++Q ++H P LS +H + C ++ G C
Sbjct: 165 DRREKWTFPLGLRGLNNLGSTCFMNAVLQALVHAPPLRNFWLSGQHNRDLCPRRTMGLLC 224
Query: 179 VSCALDEIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLN 238
+ C LD I + +G T S + +LL + W + +L QQD+HE++ LL+
Sbjct: 225 LPCDLDVIFSAMF-SGDRTPYSPA------HLLYSWWQHSTNLATYEQQDSHEFFISLLD 277
Query: 239 QLHTDHARVFGSSKA-----PDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLE 293
++H + G SK +CQCITH+ F G L++ + C+ CG + TT DP +D+SL
Sbjct: 278 RIHENE----GKSKCLYQDNEECQCITHKAFSGLLRSDVTCTTCGSTSTTYDPFIDISLT 333
Query: 294 I------------KNN-----------PKLEDCLDHFQREETL-TDFHYECQSCKQNQGV 329
+ KN P L CLD F R E L D CQSC + +
Sbjct: 334 LDSMNGFSPADCRKNRYSGGPSVNAIMPTLSGCLDFFTRSEKLGPDQKLNCQSCGEKRES 393
Query: 330 VKQLTLHKAPNVLVIQLKRFEHQLNGQ-SAKLNDRVQFPLHLNLKPHL------------ 376
KQ+++ + P +L + +KRFEH L + S K++ +Q+P LN+ P+L
Sbjct: 394 SKQMSIRRLPLLLCLHVKRFEHSLTRKTSRKIDSYLQYPFRLNMSPYLSSSIIGKRFGNR 453
Query: 377 ---FQIEDEY------IPNIAYDLLNVVSHQGTVDQGHYTTVSKTEDGQWFKFNDSVVTS 427
F E EY P+ +++ VV+H+G ++ GHY T + + G W++ +D+ +
Sbjct: 454 IFAFDGEGEYDSSSSSSPSAEFEIFAVVTHKGMLESGHYVTYLRLK-GLWYRCDDAWINE 512
Query: 428 VTEEQVLEQQAYLLFY 443
V EE V + Y+LFY
Sbjct: 513 VEEEVVRGCECYMLFY 528
>SPCC1682.12c [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 457
Score = 178 bits (451), Expect = 2e-44
Identities = 117/351 (33%), Positives = 190/351 (53%), Gaps = 23/351 (6%)
Query: 100 DFMADLVAEIPASQWDTVMEKTELPASLHRDGLQGLVNMGSTCFMSSIIQTIIHNPYFVE 159
DF+ + A IP ++ EK + GLVN+G+TCFM+S++Q + P V+
Sbjct: 92 DFVDEDPAFIPPARILFPEEKLSMEWDNIMPNAPGLVNLGNTCFMNSVLQLMTQTPPLVQ 151
Query: 160 DLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGNGPGTGKSSSVS-KGFVNLLSASWHIN 218
LLS +H +C + + CV C +++ Y N GT ++S+ G ++L I+
Sbjct: 152 YLLSGQHSLSCRMNA---CVLCRMEQHVARAYPN-KGTKRASAFKPSGIQSMLKV---IS 204
Query: 219 HHLVGSSQQDAHEYWQFLLNQLHTDHARVFGSSKAPDCQC-ITHRIFQGYLKNTLQCSQC 277
H Q+DAHE+ ++L++ + + P + + HRIF GYL+ + CS C
Sbjct: 205 SHFRPYRQEDAHEFMRYLVDAWQKSCLQNHKNLDHPSRETSVVHRIFGGYLRQQILCSVC 264
Query: 278 GFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLH 336
T ++DLS++ K + L D L HF E LT + Y C++CKQ KQ+T++
Sbjct: 265 KKPSNTYQALLDLSVDAKGS-SLADSLKHFVHAEKLTKQNKYRCENCKQLVDASKQMTIY 323
Query: 337 KAPNVLVIQLKRFEHQLNG-QSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIA--YDLLN 393
+APN+L I KRF NG QS+K++ ++ +P NL P++ PN + Y+L+
Sbjct: 324 RAPNILTIHFKRF--TFNGFQSSKISKQISYPESFNLGPYMSD------PNCSCWYELIG 375
Query: 394 VVSHQ-GTVDQGHYTTVSKTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
V+ H G+ GHY + K+ +G W KF+D V++ + ++VL QQAY+L Y
Sbjct: 376 VLVHAGGSTRSGHYYSFCKSSNGVWLKFDDDFVSNSSIDRVLNQQAYILQY 426
>Hs13435157 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 548
Score = 159 bits (403), Expect = 6e-39
Identities = 100/316 (31%), Positives = 162/316 (50%), Gaps = 22/316 (6%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGN 193
GL N+G+TCF+++ IQ + + P LLS +H +C G+ C+ C + + N
Sbjct: 123 GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHARSCH--QGSFCMLCVMQNHIVQAFAN 180
Query: 194 GPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGSSKA 253
K S F+ L I H +Q+DAHE+ ++ ++ + A + G +K
Sbjct: 181 SGNAIKPVS----FIRDLKK---IARHFRFGNQEDAHEFLRYTIDAMQK--ACLNGCAKL 231
Query: 254 P---DCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQRE 310
+ H+IF GYL++ ++CS C T DP +D++LEI+ + L+ F +
Sbjct: 232 DRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIRQAANIVRALELFVKA 291
Query: 311 ETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLH 369
+ L+ + Y C CK+ K+ T+H+ NVL + LKRF N K+ V +P
Sbjct: 292 DVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRFA---NFSGGKITKDVGYPEF 348
Query: 370 LNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVSKTEDGQWFKFNDSVVTSV 428
LN++P++ Q + + Y L V+ H G + GHY K +GQW++ NDS+V S
Sbjct: 349 LNIRPYMSQNNGD---PVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSS 405
Query: 429 TEEQVLEQQAYLLFYI 444
+ VL QQAY+LFY+
Sbjct: 406 NVKVVLNQQAYVLFYL 421
>Hs20540195 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 823
Score = 158 bits (399), Expect = 2e-38
Identities = 104/322 (32%), Positives = 166/322 (51%), Gaps = 23/322 (7%)
Query: 128 HRDGLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIA 187
HR G GL N+G+TCF ++ +Q + + P +LSH+H C + C+ C +
Sbjct: 107 HRVGA-GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKTCHAEGF--CMMCTMQAHI 163
Query: 188 CDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARV 247
N PG + FV ++ I H +Q+DAHE+ Q+ ++ + A +
Sbjct: 164 TQALSN-PG----DVIKPMFV--INEMRRIARHFRFGNQEDAHEFLQYTVDAMQK--ACL 214
Query: 248 FGSSKAP---DCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCL 304
GS+K + +IF GYL++ ++C C T DP +D++LEIK + L
Sbjct: 215 NGSNKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKAL 274
Query: 305 DHFQREETLT-DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDR 363
+ F + E L + Y+C CK+ K+ T+H++ NVL + LKRF + G+ AK
Sbjct: 275 EQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAK---D 331
Query: 364 VQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVSKTEDGQWFKFND 422
V++P +L+++P++ Q E I Y L V+ H G GHY K +G W++ ND
Sbjct: 332 VKYPEYLDIRPYMSQPNGE---PIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMND 388
Query: 423 SVVTSVTEEQVLEQQAYLLFYI 444
S+V++ VL QQAY+LFYI
Sbjct: 389 SIVSTSDIRSVLSQQAYVLFYI 410
>7295432 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 577
Score = 155 bits (392), Expect = 1e-37
Identities = 96/319 (30%), Positives = 163/319 (51%), Gaps = 23/319 (7%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHK-HCNNCDI-KSGTKCVSCALDEIACDFY 191
G++N+G+TC+++S +Q ++H P L+S + H +C++ + G+ C+ CA+ +
Sbjct: 173 GMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLADCNVAEPGSGCIICAMTKTLL--- 229
Query: 192 GNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGSS 251
T + S + F+ + S I H+V Q+DAHE+ +FL+ + + F +
Sbjct: 230 ----ATQSNQSAVRPFL-IYSKLKQICKHMVVGRQEDAHEFLRFLVEAMERAYLMRFRNY 284
Query: 252 KAPDCQCITH-----RIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLD- 305
K D Q + +IF GYL++ ++C C T DL L+I+ LED +
Sbjct: 285 KELD-QLVKETTPLGQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDIRKADSLEDAFEG 343
Query: 306 HFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQ 365
HF RE L D Y+C+ CK+ KQ +L +AP L IQLKRF N KL ++
Sbjct: 344 HFSRER-LEDMGYKCEGCKKKVSATKQFSLERAPITLCIQLKRFSMIGN----KLTKQIS 398
Query: 366 FPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQ-GHYTTVSKTEDGQWFKFNDSV 424
F ++L + + + + Y L+++V+H G GHYT + T+ G ++ F+DS
Sbjct: 399 FKSRIDLSKYAARSQAAQAQPLTYRLVSMVTHLGASQHCGHYTAIGSTDTGSFYNFDDSY 458
Query: 425 VTSVTEEQVLEQQAYLLFY 443
V + V AY++F+
Sbjct: 459 VRPIAMHSVCNTNAYIMFF 477
>7300711 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 888
Score = 146 bits (369), Expect = 5e-35
Identities = 101/334 (30%), Positives = 166/334 (49%), Gaps = 29/334 (8%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDF 190
GL GL N+G+TC+M+SI+Q + + P E +S K+ N I K ++E+A
Sbjct: 553 GLTGLKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNY--ISRSNKTNGQVIEEVAALI 610
Query: 191 YGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTD------- 243
G K + +L G QQD+HE+ L++ LH+D
Sbjct: 611 KELWNGQYKCVASR----DLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDLQTLHVP 666
Query: 244 --HARVFGSSKA-----PDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKN 296
+ S KA + + +F G +K+T++C C T + +LSLE+
Sbjct: 667 RQREMISASEKAWLEFTKAKESMILHLFYGQMKSTVKCVACHKESATYESFSNLSLELPP 726
Query: 297 NP---KLEDCLDHFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRF--EH 351
N +L C+D + E + ++ C SCK + +K+L + K P VLV+ LKRF +
Sbjct: 727 NSNVCQLNQCMDMYFSGERIHGWN--CPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADP 784
Query: 352 QLNGQSAKLNDRVQFPL-HLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVS 410
+G K + ++FPL +L++ P++ + E + Y L V +H GT++ GHYT
Sbjct: 785 SNSGSYMKKQNYLRFPLENLDMNPYIARAESRAVTPKTYQLYAVSNHYGTMEGGHYTAFC 844
Query: 411 KTED-GQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
K+ + G+WFKF+D VV+++ V+ AY+LFY
Sbjct: 845 KSANYGKWFKFDDQVVSALDSSNVVSSAAYILFY 878
>Hs22044530 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 565
Score = 146 bits (368), Expect = 7e-35
Identities = 100/337 (29%), Positives = 165/337 (48%), Gaps = 34/337 (10%)
Query: 117 VMEKTELPASLHRDGL--QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKS 174
++ + +LP S R GL NMG+TC++++ +Q + + P +LS +H C
Sbjct: 97 LVPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHK 156
Query: 175 GTKCVSCALD-EIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYW 233
G C+ C + I + G S +++ GF Q+DAHE+
Sbjct: 157 G--CMLCTMQAHITRALHNPGHVIQPSQALAAGFHR--------------GKQEDAHEFL 200
Query: 234 QFLLNQLHT----DHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMD 289
F ++ + H +V SK + H+IF GY ++ ++C C T DP +D
Sbjct: 201 MFTVDAMKKACLPGHKQVDHHSKDTT---LIHQIFGGYWRSQIKCLHCHGISDTFDPYLD 257
Query: 290 LSLEIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKR 348
++L+I+ ++ L+ + E L + Y C C Q K LTLH + VL++ LKR
Sbjct: 258 IALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKR 317
Query: 349 FEHQLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYT 407
F + AK VQ+P L+++P++ Q + + Y L V+ H G + GHY
Sbjct: 318 FSDVTGNKIAK---NVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCYNGHYF 371
Query: 408 TVSKTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFYI 444
+ K ++GQW+K +D+ VT+ + VL QQAY+LFYI
Sbjct: 372 SYVKAQEGQWYKMDDAEVTAASITSVLSQQAYVLFYI 408
>Hs22044559 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 145 bits (367), Expect = 9e-35
Identities = 100/334 (29%), Positives = 163/334 (47%), Gaps = 34/334 (10%)
Query: 120 KTELPASLHRDGL--QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTK 177
+ +LP S R GL NMG+TC++++ +Q + + P +LS +H C G
Sbjct: 65 REKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKG-- 122
Query: 178 CVSCALD-EIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFL 236
C+ C + I + G S +++ GF Q+DAHE+ F
Sbjct: 123 CMLCTMQAHITRALHNPGHVIQPSQALAAGFHR--------------GKQEDAHEFLMFT 168
Query: 237 LNQLHT----DHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSL 292
++ + H +V SK + H+IF GY ++ ++C C T DP +D++L
Sbjct: 169 VDAMKKACLPGHKQVDHHSKDTT---LIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIAL 225
Query: 293 EIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEH 351
+I+ ++ L+ + E L + Y C C Q K LTLH + VL++ LKRF
Sbjct: 226 DIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSD 285
Query: 352 QLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVS 410
+ AK VQ+P L+++P++ Q + + Y L V+ H G + GHY +
Sbjct: 286 VTGNKIAK---NVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYFSYV 339
Query: 411 KTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFYI 444
K ++GQW+K +D+ VT+ + VL QQAY+LFYI
Sbjct: 340 KAQEGQWYKMDDAEVTASSITSVLTQQAYVLFYI 373
>Hs22044551 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 145 bits (367), Expect = 9e-35
Identities = 100/334 (29%), Positives = 163/334 (47%), Gaps = 34/334 (10%)
Query: 120 KTELPASLHRDGL--QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTK 177
+ +LP S R GL NMG+TC++++ +Q + + P +LS +H C G
Sbjct: 65 REKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKG-- 122
Query: 178 CVSCALD-EIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFL 236
C+ C + I + G S +++ GF Q+DAHE+ F
Sbjct: 123 CMLCTMQAHITRALHNPGHVIQPSQALAAGFHR--------------GKQEDAHEFLMFT 168
Query: 237 LNQLHT----DHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSL 292
++ + H +V SK + H+IF GY ++ ++C C T DP +D++L
Sbjct: 169 VDAMKKACLPGHKQVDHHSKDTT---LIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIAL 225
Query: 293 EIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEH 351
+I+ ++ L+ + E L + Y C C Q K LTLH + VL++ LKRF
Sbjct: 226 DIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSD 285
Query: 352 QLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVS 410
+ AK VQ+P L+++P++ Q + + Y L V+ H G + GHY +
Sbjct: 286 VTGNKIAK---NVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYFSYV 339
Query: 411 KTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFYI 444
K ++GQW+K +D+ VT+ + VL QQAY+LFYI
Sbjct: 340 KAQEGQWYKMDDAEVTASSITSVLTQQAYVLFYI 373
>Hs22044543 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 145 bits (367), Expect = 9e-35
Identities = 100/334 (29%), Positives = 163/334 (47%), Gaps = 34/334 (10%)
Query: 120 KTELPASLHRDGL--QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTK 177
+ +LP S R GL NMG+TC++++ +Q + + P +LS +H C G
Sbjct: 65 REKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKG-- 122
Query: 178 CVSCALD-EIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFL 236
C+ C + I + G S +++ GF Q+DAHE+ F
Sbjct: 123 CMLCTMQAHITRALHNPGHVIQPSQALAAGFHR--------------GKQEDAHEFLMFT 168
Query: 237 LNQLHT----DHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSL 292
++ + H +V SK + H+IF GY ++ ++C C T DP +D++L
Sbjct: 169 VDAMKKACLPGHKQVDHHSKDTT---LIHQIFGGYWRSQIKCLHCHRISDTFDPYLDIAL 225
Query: 293 EIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEH 351
+I+ ++ L+ + E L + Y C C Q K LTLH + VL++ LKRF
Sbjct: 226 DIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSD 285
Query: 352 QLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVS 410
+ AK VQ+P L+++P++ Q + + Y L V+ H G + GHY +
Sbjct: 286 VTGNKIAK---NVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYFSYV 339
Query: 411 KTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFYI 444
K ++GQW+K +D+ VT+ + VL QQAY+LFYI
Sbjct: 340 KAQEGQWYKMDDAEVTASSITSVLTQQAYVLFYI 373
>Hs22044565 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 398
Score = 145 bits (366), Expect = 1e-34
Identities = 100/334 (29%), Positives = 163/334 (47%), Gaps = 34/334 (10%)
Query: 120 KTELPASLHRDGL--QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTK 177
+ +LP S R GL NMG+TC++++ +Q + + P +LS +H C G
Sbjct: 65 REKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKG-- 122
Query: 178 CVSCALD-EIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFL 236
C+ CA+ I + G S +++ GF Q+DAHE+ F
Sbjct: 123 CMLCAMQAHITRALHNPGHVIQPSQALAAGFHR--------------GKQEDAHEFLMFT 168
Query: 237 LNQLHT----DHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSL 292
++ + H +V SK + H+IF GY ++ ++C C T DP +D++L
Sbjct: 169 VDAMKKACLPGHKQVDHHSKDTT---LIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIAL 225
Query: 293 EIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEH 351
+I+ ++ L+ + E L + Y C C Q K L LH + VL++ LKRF
Sbjct: 226 DIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLALHTSAKVLILVLKRFSD 285
Query: 352 QLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVS 410
+ AK VQ+P L+++P++ Q + + Y L V+ H G + GHY +
Sbjct: 286 VTGNKIAK---NVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYFSYV 339
Query: 411 KTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFYI 444
K ++GQW+K +D+ VT+ + VL QQAY+LFYI
Sbjct: 340 KAQEGQWYKIDDAEVTASSITSVLTQQAYVLFYI 373
>Hs22044547 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 145 bits (366), Expect = 1e-34
Identities = 100/334 (29%), Positives = 163/334 (47%), Gaps = 34/334 (10%)
Query: 120 KTELPASLHRDGL--QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTK 177
+ +LP S R GL NMG+TC++++ +Q + + P +LS +H C G
Sbjct: 65 REKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPSLANYMLSREHSQTCHRHKG-- 122
Query: 178 CVSCALD-EIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFL 236
C+ C + I + G S +++ GF Q+DAHE+ F
Sbjct: 123 CMLCTMQAHITRALHNPGHVIQPSQALAAGFHR--------------GKQEDAHEFLMFT 168
Query: 237 LNQLHT----DHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSL 292
++ + H +V SK + H+IF GY ++ ++C C T DP +D++L
Sbjct: 169 VDAMKKACLPGHKQVDHHSKDTT---LIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIAL 225
Query: 293 EIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEH 351
+I+ ++ L+ + E L + Y C C Q K LTLH + VL++ LKRF
Sbjct: 226 DIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSD 285
Query: 352 QLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVS 410
+ AK VQ+P L+++P++ Q + + Y L V+ H G + GHY +
Sbjct: 286 VTGNKIAK---NVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCYNGHYFSYV 339
Query: 411 KTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFYI 444
K ++GQW+K +D+ VT+ + VL QQAY+LFYI
Sbjct: 340 KAQEGQWYKMDDAEVTASSITSVLTQQAYVLFYI 373
>Hs22044539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 1074
Score = 145 bits (365), Expect = 2e-34
Identities = 100/333 (30%), Positives = 163/333 (48%), Gaps = 34/333 (10%)
Query: 120 KTELPASLHRDGL--QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTK 177
+ +LP S R GL NMG+TC++++ +Q + + P +LS +H C G
Sbjct: 65 REKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCYRHKG-- 122
Query: 178 CVSCALD-EIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFL 236
C+ C + I + G S +++ GF Q+DAHE+ F
Sbjct: 123 CMLCTMQAHITRALHNPGHVIQPSQALAAGFHR--------------GKQEDAHEFLMFT 168
Query: 237 LNQLHT----DHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSL 292
++ + H +V SK + H+IF GY ++ ++C C T DP +D++L
Sbjct: 169 VDAMKKACLPGHKQVDHHSKDTT---LIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIAL 225
Query: 293 EIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEH 351
+I+ ++ L+ + E L + Y C C Q K LTLH + VL++ LKRF
Sbjct: 226 DIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSD 285
Query: 352 QLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSK 411
+ AK VQ+P L+++P++ Q + + Y L V+ H G + GHY + K
Sbjct: 286 VTGNKIAK---NVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGCYN-GHYFSYVK 338
Query: 412 TEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFYI 444
++GQW+K +D+ VT+ + VL QQAY+LFYI
Sbjct: 339 AQEGQWYKMDDAEVTASSITSVLTQQAYVLFYI 371
Score = 141 bits (356), Expect = 2e-33
Identities = 99/334 (29%), Positives = 162/334 (47%), Gaps = 39/334 (11%)
Query: 120 KTELPASLHRDGL--QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTK 177
+ +LP S R GL NMG+TC++++ +Q + + P +LS +H N
Sbjct: 614 REKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQN-------G 666
Query: 178 CVSCALD-EIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFL 236
C+ C + I + G S +++ GF Q+DAHE+ F
Sbjct: 667 CMLCTMQAHITRALHNPGHVIQPSQALAAGFHR--------------GKQEDAHEFLMFT 712
Query: 237 LNQLHT----DHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSL 292
++ + H +V SK + H+IF GY ++ ++C C T DP +D++L
Sbjct: 713 VDAMKKACLPGHKQVDHHSKDTT---LIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIAL 769
Query: 293 EIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEH 351
+I+ ++ L+ + E L + Y C C Q K LTLH + VL++ LKRF
Sbjct: 770 DIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSD 829
Query: 352 QLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVS 410
+ AK VQ+P L+++P++ Q + + Y L V+ H G + GHY +
Sbjct: 830 VTGNKIAK---NVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYFSYV 883
Query: 411 KTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFYI 444
K ++GQW+K +D+ VT+ + VL QQAY+LFYI
Sbjct: 884 KAQEGQWYKMDDAEVTASSITSVLTQQAYVLFYI 917
>At3g14400 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 661
Score = 144 bits (364), Expect = 2e-34
Identities = 94/321 (29%), Positives = 163/321 (50%), Gaps = 31/321 (9%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDE-----IAC 188
GL N+G+TC+++S++Q + P L+HKH ++C + C C +++ ++
Sbjct: 16 GLRNLGNTCYLNSVLQCLTFTPPLANFCLTHKHSSHCTKRD---CPFCIVEKRIARSLSV 72
Query: 189 DFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARV- 247
D + P K SS K F H Q+DAHE+ +++++ H R+
Sbjct: 73 DLTTDAPN--KISSCLKIFAE----------HFKLGRQEDAHEFLRYVIDACHNTSLRLK 120
Query: 248 ---FGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCL 304
+ ++ + + IF G L++ ++C CG D IMD+SLEI + +++ L
Sbjct: 121 KLRYNGNEPFNGNSVVKEIFGGALQSQVKCLSCGAESNKADEIMDISLEILQSSSVKESL 180
Query: 305 DHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDR 363
F + E L + Y C+SC++ KQ+++ +APN+LVIQLKRF G K++
Sbjct: 181 QKFFQSEILDGNNKYRCESCEKLVTARKQMSILQAPNILVIQLKRFGGIFGG---KIDKA 237
Query: 364 VQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVSKTEDGQWFKFND 422
+ F L L + + + P Y L ++ H G + + GHY K G+W+ ND
Sbjct: 238 ISFGEILVLSNFMSKASKD--PQPEYKLFGIIVHSGFSPESGHYYAYVKDSLGRWYCCND 295
Query: 423 SVVTSVTEEQVLEQQAYLLFY 443
S V+ T ++VL ++AY+LF+
Sbjct: 296 SFVSLSTLQEVLSEKAYILFF 316
>Hs22044534 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 143 bits (361), Expect = 5e-34
Identities = 99/334 (29%), Positives = 162/334 (47%), Gaps = 34/334 (10%)
Query: 120 KTELPASLHRDGL--QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTK 177
+ +LP S R GL NMG+TC++++ +Q + + +LS +H C G
Sbjct: 65 REKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTTPLANYMLSREHSQTCHRHKG-- 122
Query: 178 CVSCALD-EIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFL 236
C+ C + I + G S +++ GF Q+DAHE+ F
Sbjct: 123 CMLCTMQAHITRALHNPGHVIQPSQALAAGFHR--------------GKQEDAHEFLMFT 168
Query: 237 LNQLHTD----HARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSL 292
++ + H +V SK + H+IF GY ++ ++C C T DP +D++L
Sbjct: 169 VDAMKKACLPRHKQVDHHSKDTT---LIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIAL 225
Query: 293 EIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEH 351
+I+ ++ L+ + E L + Y C C Q K LTLH + VL++ LKRF
Sbjct: 226 DIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSD 285
Query: 352 QLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVS 410
+ AK VQ+P L+++P++ Q + + Y L V+ H G + GHY +
Sbjct: 286 VTGNKIAK---NVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYFSYV 339
Query: 411 KTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFYI 444
K ++GQW+K +D+ VT+ + VL QQAY+LFYI
Sbjct: 340 KAQEGQWYKMDDAEVTAASITSVLSQQAYVLFYI 373
>Hs18557591 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 142 bits (359), Expect = 8e-34
Identities = 95/318 (29%), Positives = 157/318 (48%), Gaps = 32/318 (10%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALD-EIACDFYG 192
GL NMG+TC++++ +Q + + P +L +H C G C+ C + I +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYKPPLANYMLFREHSQTCHRHKG--CMLCTMQAHITRALHI 138
Query: 193 NGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHT----DHARVF 248
G S +++ GF Q+DAHE+ F ++ + H +V
Sbjct: 139 PGHVIQPSQALAAGFHR--------------GKQEDAHEFLMFTVDAMRKACLPGHKQVD 184
Query: 249 GSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQ 308
SK + H+IF GY ++ ++C C T DP +D++L+I+ ++ L+
Sbjct: 185 RHSKDTT---LIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLV 241
Query: 309 REETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFP 367
+ E L + Y C C Q K LTLH + VL++ LKRF + AK VQ+P
Sbjct: 242 KPEELNGENAYHCGVCLQRAPASKTLTLHNSAKVLILVLKRFPDVTGNKIAK---NVQYP 298
Query: 368 LHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVSKTEDGQWFKFNDSVVT 426
L+++P++ Q + + Y L V+ H G + GHY++ K ++GQW+K +D+ VT
Sbjct: 299 ECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYSSYVKAQEGQWYKMDDAEVT 355
Query: 427 SVTEEQVLEQQAYLLFYI 444
+ + VL QQAY+LFYI
Sbjct: 356 ASSITSVLSQQAYVLFYI 373
>At5g46740 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 732
Score = 142 bits (358), Expect = 1e-33
Identities = 103/315 (32%), Positives = 150/315 (46%), Gaps = 17/315 (5%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCAL-DEIACDFYG 192
GL N G+TCF++S++Q H ++ L S + N C+ + CV AL D I
Sbjct: 164 GLYNSGNTCFIASVLQCFTHTVPLIDSLRSFMYGNPCNCGNEKFCVMQALRDHIELALRS 223
Query: 193 NGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHT---DHARVFG 249
+G G + + S+ + INH Q+DAHE+ Q L++L D G
Sbjct: 224 SGYGINIDRF--RDNLTYFSSDFMINH------QEDAHEFLQSFLDKLERCCLDPKNQLG 275
Query: 250 SSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQR 309
S + D I +F G L +TL C C T +P + SLEI++ L L+ F
Sbjct: 276 SVSSQDLN-IVDNVFGGGLMSTLCCCNCNSVSNTFEPSLGWSLEIEDVNTLWKALESFTC 334
Query: 310 EETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLH 369
E L D C +CK+ KQL K P V LKRF + K+ D ++FPL
Sbjct: 335 VEKLED-QLTCDNCKEKVTKEKQLRFDKLPPVATFHLKRFTND-GVTMEKIFDHIEFPLE 392
Query: 370 LNLKPHLFQIEDEYIPNIAYDLLNVVSHQGT-VDQGHYTTVSKTEDGQWFKFNDSVVTSV 428
L+L P + D + + Y L V H G GHY++ ++ W F+DS VT +
Sbjct: 393 LDLSPFMSSNHDPEV-STRYHLYAFVEHIGIRATFGHYSSYVRSAPETWHNFDDSKVTRI 451
Query: 429 TEEQVLEQQAYLLFY 443
+EE+VL + AY+LFY
Sbjct: 452 SEERVLSRPAYILFY 466
>Hs22044537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 141 bits (355), Expect = 2e-33
Identities = 95/318 (29%), Positives = 156/318 (48%), Gaps = 32/318 (10%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALD-EIACDFYG 192
GL NMG+TC++++ +Q + + P +L +H C G C+ C + I +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYKPPLANYMLFREHSQTCHRHKG--CMLCTMQAHITRALHI 138
Query: 193 NGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHT----DHARVF 248
G S +++ GF Q+DAHE+ F ++ + H +V
Sbjct: 139 PGHVIQPSQALAAGFHR--------------GKQEDAHEFLMFTVDAMRKACLPGHKQVD 184
Query: 249 GSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQ 308
SK + H+IF GY ++ ++C C T DP +D++L+I+ ++ L+
Sbjct: 185 RHSKDTT---LIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLV 241
Query: 309 REETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFP 367
+ E L + Y C C Q K LTLH + VL++ LKRF + AK VQ+P
Sbjct: 242 KPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAK---NVQYP 298
Query: 368 LHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVSKTEDGQWFKFNDSVVT 426
L+++P++ Q + + Y L V+ H G + GHY + K ++GQW+K +D+ VT
Sbjct: 299 ECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVT 355
Query: 427 SVTEEQVLEQQAYLLFYI 444
+ + VL QQAY+LFYI
Sbjct: 356 ASSITSVLTQQAYVLFYI 373
>Hs22044541 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 525
Score = 140 bits (353), Expect = 4e-33
Identities = 98/334 (29%), Positives = 162/334 (48%), Gaps = 39/334 (11%)
Query: 120 KTELPASLHRDGL--QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTK 177
+ +LP S R GL NMG+TC++++ +Q + + P +LS +H N
Sbjct: 65 REKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQN-------G 117
Query: 178 CVSCALD-EIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFL 236
C+ C + I + G S +++ GF Q+DAHE+ F
Sbjct: 118 CMLCTMQAHITRALHNPGHVIQPSQALAAGFHR--------------GKQEDAHEFLMFT 163
Query: 237 LNQLHT----DHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSL 292
++ + H +V +K + H+IF GY ++ ++C C T DP +D++L
Sbjct: 164 VDAMKKACLPGHKQVDHHAKDTT---LIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIAL 220
Query: 293 EIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEH 351
+I+ ++ L+ + E L + Y C C Q K LTLH + VL++ LKRF
Sbjct: 221 DIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSD 280
Query: 352 QLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVS 410
+ AK VQ+P L+++P++ Q + + Y L V+ H G + GHY +
Sbjct: 281 VTGNKIAK---NVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYFSYV 334
Query: 411 KTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFYI 444
K ++GQW+K +D+ VT+ + VL QQAY+LFYI
Sbjct: 335 KAQEGQWYKMDDAEVTASSITSVLTQQAYVLFYI 368
>Hs5730110 [O] KOG1867 Ubiquitin-specific protease
Length = 521
Score = 139 bits (349), Expect = 1e-32
Identities = 138/509 (27%), Positives = 211/509 (41%), Gaps = 112/509 (22%)
Query: 33 ADFKNRTMRTMRCMDCGEISCGSTFICLQCG--FCGCWNNNHFLDHSQ------------ 78
A F N + + C C S S ++CL C CG + N H H +
Sbjct: 17 AKFPNGSPSSWCCSVCR--SNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQVPLTNHKKS 74
Query: 79 ----KLGHIFGVNSSNGLVFCFRCGDFMAD-----LVAEIPASQWDTVMEKTELPASLHR 129
K+ H ++ S+ +C+RC DF+ + LV ++ + +E + A H+
Sbjct: 75 EKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQN--LENSAFTADRHK 132
Query: 130 DG-----------------------LQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKH 166
GL N+G+TCFM++I+Q++ + F K
Sbjct: 133 KRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFC---CYFKE 189
Query: 167 CNNCDIKSG---------TKCVSCALDEIACDFYGNGPGTGKSSSVSKGFVNLLSASWHI 217
++++G T+ + +F + S + +L W I
Sbjct: 190 LPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKI 249
Query: 218 NHHLVGSSQQDAHEY----------------------WQF---LLNQLHTDHARVFGSSK 252
+ G QQDAHE+ QF +L L + + G+S
Sbjct: 250 MPNFRGYQQQDAHEFNALPFGPPTLGNFRAVSTVFPAQQFCRRILLCLQVNKCCINGAST 309
Query: 253 APDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEI------------KNNP-- 298
+ IF G L+N + C CG DP +DLSL+I +N P
Sbjct: 310 ------VVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVC 363
Query: 299 KLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQS 357
L DCL F E L + Y C CK+ Q K+ + K P VL + LKRF H
Sbjct: 364 SLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRF-HWTAYLR 422
Query: 358 AKLNDRVQFPLH-LNLKPHLFQIEDEYIPNIAYDLLNVVSHQGT-VDQGHYTTVSKTEDG 415
K++ V+FPL L++K +L + E+ + YDL VV H G+ V GHYT + T +G
Sbjct: 423 NKVDTYVEFPLRGLDMKWYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYA-THEG 481
Query: 416 QWFKFNDSVVTSVTEEQVLEQQAYLLFYI 444
+WF FNDS VT EE V++ +AY+LFY+
Sbjct: 482 RWFHFNDSTVTLTDEETVVKAKAYILFYV 510
>Hs22044528 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 446
Score = 138 bits (347), Expect = 2e-32
Identities = 91/313 (29%), Positives = 153/313 (48%), Gaps = 30/313 (9%)
Query: 138 MGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALD-EIACDFYGNGPG 196
MG+TC++++ +Q + + P +LS +H C G C+ C + I + G
Sbjct: 1 MGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKG--CMLCTMQAHITRALHNPGHV 58
Query: 197 TGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTD----HARVFGSSK 252
S +++ GF Q+DAHE+ F ++ + H +V SK
Sbjct: 59 IQPSQALAAGFHR--------------GKQEDAHEFLMFTVDAMKKACLPRHKQVDHHSK 104
Query: 253 APDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQREET 312
+ H+IF GY ++ ++C C T DP +D++L+I+ ++ L+ + E
Sbjct: 105 DTT---LIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEE 161
Query: 313 LTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLN 371
L + Y C C Q K LTLH + VL++ LKRF + AK VQ+P L+
Sbjct: 162 LNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAK---NVQYPECLD 218
Query: 372 LKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTEDGQWFKFNDSVVTSVTEE 431
++P++ Q + + Y +L V + + GHY + K ++GQW+K +D+ VT+ +
Sbjct: 219 MQPYMSQQNTGPLVYVLYAVL--VHAEWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSIT 276
Query: 432 QVLEQQAYLLFYI 444
VL QQAY+LFYI
Sbjct: 277 SVLSQQAYVLFYI 289
>HsM19923759 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 605
Score = 137 bits (344), Expect = 4e-32
Identities = 108/345 (31%), Positives = 166/345 (47%), Gaps = 45/345 (13%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIA--- 187
GL GL N+G+TCFM+SI+Q + + + L + D+ G+ + ++E A
Sbjct: 265 GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMR--DLHHGSNAHTALVEEFAKLI 322
Query: 188 CDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARV 247
+ + P S S K + + VG +QQDA E+ +FLL+ LH + RV
Sbjct: 323 QTIWTSSPNDVVSPSEFKTQIQRYAP------RFVGYNQQDAQEFLRFLLDGLHNEVNRV 376
Query: 248 FGSSKA--------PDCQ--------------CITHRIFQGYLKNTLQCSQCGFSKTTID 285
K+ PD + +F G LK++L C+ CG+ T D
Sbjct: 377 TLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFD 436
Query: 286 PIMDLSLEI--KNNPK--LEDCLDHFQREETLT-DFHYECQSCKQNQGVVKQLTLHKAPN 340
P DLSL I + P+ L DC+ F +E+ L D C C+ + +K+ ++ + P
Sbjct: 437 PFWDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPK 496
Query: 341 VLVIQLKRFEHQLNGQSAKLNDRVQFPLH-LNLKPHLFQIEDEYIPNIAYDLLNVVSHQG 399
+LV+ LKRF + +++KL V FPL L+L+ + E + Y+L V +H G
Sbjct: 497 ILVLHLKRFS-ESRIRTSKLTTFVNFPLRDLDLR----EFASENTNHAVYNLYAVSNHSG 551
Query: 400 TVDQGHYTTVSKTE-DGQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
T GHYT ++ G+W FNDS VT ++ QV AYLLFY
Sbjct: 552 TTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFY 596
>Hs21361712 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 605
Score = 137 bits (344), Expect = 4e-32
Identities = 108/345 (31%), Positives = 166/345 (47%), Gaps = 45/345 (13%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIA--- 187
GL GL N+G+TCFM+SI+Q + + + L + D+ G+ + ++E A
Sbjct: 265 GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMR--DLHHGSNAHTALVEEFAKLI 322
Query: 188 CDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARV 247
+ + P S S K + + VG +QQDA E+ +FLL+ LH + RV
Sbjct: 323 QTIWTSSPNDVVSPSEFKTQIQRYAP------RFVGYNQQDAQEFLRFLLDGLHNEVNRV 376
Query: 248 FGSSKA--------PDCQ--------------CITHRIFQGYLKNTLQCSQCGFSKTTID 285
K+ PD + +F G LK +L C+ CG+ T D
Sbjct: 377 TLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKGSLTCTDCGYCSTVFD 436
Query: 286 PIMDLSLEI--KNNPK--LEDCLDHFQREETLT-DFHYECQSCKQNQGVVKQLTLHKAPN 340
P DLSL I + P+ L DC+ F +E+ L D C C+ + +K+ ++ + P
Sbjct: 437 PFWDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPK 496
Query: 341 VLVIQLKRFEHQLNGQSAKLNDRVQFPLH-LNLKPHLFQIEDEYIPNIAYDLLNVVSHQG 399
+LV++LKRF + +++KL V FPL L+L+ + E + Y+L V +H G
Sbjct: 497 ILVLRLKRFS-ESRIRTSKLTTFVNFPLRDLDLR----EFASENTNHAVYNLYAVSNHSG 551
Query: 400 TVDQGHYTTVSKTE-DGQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
T GHYT ++ G+W FNDS VT ++ QV AYLLFY
Sbjct: 552 TTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFY 596
>At1g17110 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 891
Score = 135 bits (339), Expect = 2e-31
Identities = 95/321 (29%), Positives = 157/321 (48%), Gaps = 25/321 (7%)
Query: 133 QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYG 192
+GLVN G++C+ ++++Q++ V LL H +C K C+ C L++
Sbjct: 405 RGLVNCGNSCYANAVLQSLTCTKPLVAYLLRRSHSRSCSGKDW--CLMCELEQHVMMLRE 462
Query: 193 NGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGSSK 252
+G S +LS IN + SQ+DAHE+ + L+ + + G
Sbjct: 463 SGGPLSAS--------RILSHMRSINCQIGDGSQEDAHEFLRLLVASMQSICLERLGGET 514
Query: 253 APDCQC----ITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKN-NPKLEDCLDHF 307
D + + +F G L++ ++C +C + IMDL+LEI L+D L F
Sbjct: 515 KVDPRLQETTLVQHMFGGRLRSKVKCLRCDHESERYENIMDLTLEIYGWVESLQDALTQF 574
Query: 308 QREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQF 366
R E L + Y C C K+L++H+APN+L I LKRF+ G+ K+N + F
Sbjct: 575 TRPEDLDGENMYRCSRCAGYVRARKELSIHEAPNILTIVLKRFQE---GRYGKINKCISF 631
Query: 367 PLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVD---QGHYTTVSKTEDGQWFKFNDS 423
P L++ P + + D +P + Y L V+ H T++ GHY + K G W++ +DS
Sbjct: 632 PEMLDMIPFMTRTGD--VPPL-YMLYAVIVHLDTLNASFSGHYISYVKDLRGNWYRIDDS 688
Query: 424 VVTSVTEEQVLEQQAYLLFYI 444
+ V QV+ + AY+LFY+
Sbjct: 689 EIHPVPMTQVMSEGAYMLFYM 709
>At4g31670 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 631
Score = 134 bits (338), Expect = 2e-31
Identities = 101/319 (31%), Positives = 155/319 (47%), Gaps = 25/319 (7%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGN 193
GL+N G++CF + I+Q + V LL H C C L C+F +
Sbjct: 169 GLMNCGNSCFANVILQCLSWTRPLVAYLLEKGHKRECMRNDW-----CFL----CEFQTH 219
Query: 194 GPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGSSKA 253
+S +N++S +I L Q+DAHE+ ++ ++ + + FG K
Sbjct: 220 VERASQSRFPFSP-MNIISRLTNIGGTLGYGRQEDAHEFMRYAIDMMQSVCLDEFGGEKI 278
Query: 254 --PDCQCIT--HRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNP-KLEDCLDHFQ 308
P Q T IF G L++ +QC+ C + +MDL +E+ + LE+CLD F
Sbjct: 279 VPPRSQETTLIQYIFGGLLQSQVQCTVCNHVSDQYENMMDLIVEMHGDAGSLEECLDQFT 338
Query: 309 REETLT-DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFP 367
EE L D Y+C C K+LT+ +APN+L I LKR++ G+ KLN R+ FP
Sbjct: 339 AEEWLHGDNMYKCDRCSDYVKACKRLTIRRAPNILTIALKRYQ---GGRYGKLNKRISFP 395
Query: 368 LHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQ---GHYTTVSKTEDGQWFKFNDSV 424
L+L P++ + D + Y L V+ H ++ GHY K G W++ +DS
Sbjct: 396 ETLDLNPYMSEGGDG---SDVYKLYAVIVHLDMLNASFFGHYICYIKDFCGNWYRIDDSE 452
Query: 425 VTSVTEEQVLEQQAYLLFY 443
+ SV E VL Q+AY+L Y
Sbjct: 453 IESVELEDVLSQRAYMLLY 471
>Hs4827054 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 1118
Score = 132 bits (331), Expect = 1e-30
Identities = 104/341 (30%), Positives = 163/341 (47%), Gaps = 39/341 (11%)
Query: 132 LQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDF- 190
L GL N+G+TC+M+SI+Q + + P+ + +++C DI + E+A +F
Sbjct: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYF--NRNCYQDDINRSN--LLGHKGEVAEEFG 831
Query: 191 -YGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARV-- 247
TG+ +S + IN G SQQD+ E FL++ LH D +
Sbjct: 832 IIMKALWTGQYRYISPKDFKITIGK--INDQFAGYSQQDSQELLLFLMDGLHEDLNKADN 889
Query: 248 -----------FGSSKAPDCQCITHR---------IFQGYLKNTLQCSQCGFSKTTIDPI 287
KA + H+ +FQG K+T+QC C T +
Sbjct: 890 RKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAF 949
Query: 288 MDLSLEIKNNPK--LEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVI 344
M LSL + + K L+DCL F +EE LTD + + C C+ + +K++ + K P VL++
Sbjct: 950 MYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLV 1009
Query: 345 QLKRFEHQLNGQSAKLNDRVQFPL-HLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQ 403
LKRF + + KL V FPL +L+L ++ ++ Y+L +V +H G +D
Sbjct: 1010 HLKRFSYDGRWKQ-KLQTSVDFPLENLDLSQYVIGPKNNLKK---YNLFSVSNHYGGLDG 1065
Query: 404 GHYTTVSKTEDGQ-WFKFNDSVVTSVTEEQVLEQQAYLLFY 443
GHYT K Q WFKF+D V+ ++ V AY+LFY
Sbjct: 1066 GHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFY 1106
>7295645 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 857
Score = 132 bits (331), Expect = 1e-30
Identities = 105/359 (29%), Positives = 160/359 (44%), Gaps = 78/359 (21%)
Query: 130 DGLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACD 189
+GL GL N+G+TCFM+S+IQ + H L SH
Sbjct: 529 EGLCGLRNIGNTCFMNSVIQCLSHTQELTRFLRSH------------------------- 563
Query: 190 FYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGS-----------------SQQDAHEY 232
+G+ + K + F L+ W N H V +QQDA E+
Sbjct: 564 -HGSRSLSTKDQQILHEFAKLIQEMWTANVHTVTPMELKRAFSTKHRMYSDYNQQDAQEF 622
Query: 233 WQFLLNQLHTD-HARVFGSS----------KAPDC---------QCITHRIFQGYLKNTL 272
+F L+ LH+ ++ V G + K D + +F G LK+TL
Sbjct: 623 LRFFLDSLHSALNSGVKGETLNIDDNLSDNKKADLTWEWYTRHENSLVRDLFVGQLKSTL 682
Query: 273 QCSQCGFSKTTIDPIMDLSLEIKNNP--KLEDCLDHFQREETLT-DFHYECQSCKQNQGV 329
+C+ CG + T DP DLS+ + ++ KLE CLD F REE L D C CK +
Sbjct: 683 KCTTCGNTSVTFDPFWDLSVPLPSSSRCKLEACLDLFIREEVLDGDEMPTCAKCKTRRKC 742
Query: 330 VKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPL---HLNLKPHLFQIEDEYIPN 386
K T+ + P LVI LKRF + +KL++ V+FP LN+ + N
Sbjct: 743 TKSFTIQRFPKYLVIHLKRFSET---RWSKLSNIVEFPTSDSELNMGSYGANSNS----N 795
Query: 387 IAYDLLNVVSHQGTVDQGHYTTVSK-TEDGQWFKFNDSVVT-SVTEEQVLEQQAYLLFY 443
+ Y L + +H G+ GHY + K +W +FND++V+ +++E ++ AY+LFY
Sbjct: 796 VHYSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFNDNIVSDALSENHLVSSSAYILFY 854
>At4g17890_2 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 544
Score = 130 bits (327), Expect = 4e-30
Identities = 101/326 (30%), Positives = 156/326 (46%), Gaps = 45/326 (13%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHK-----HCNN---CDIKSGTKCVSCALDE 185
GL N+G++CF++S+ Q H +E LLS + HC N C I++ + AL
Sbjct: 26 GLWNLGNSCFLNSVFQCFTHTVPLIESLLSFRYEVPCHCGNEFFCVIRAIRYHIEAALRP 85
Query: 186 IACD-----FYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQL 240
C F+ N +N S + Q+DAHE+ Q L +L
Sbjct: 86 ERCPIAPYFFFDN--------------LNYFSPDFQ------RYQQEDAHEFLQAFLEKL 125
Query: 241 HTDHARVFGSSKAPDCQCITHR-IFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPK 299
+ GS + IT + +F G L + L+C C + T + + LSLEI++
Sbjct: 126 E-----ICGSDRTSFRGDITSQDVFSGRLISGLRCCNCDYVSETYEKSVGLSLEIEDVDT 180
Query: 300 LEDCLDHFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNG-QSA 358
L L+ F R E L D C +C + KQL L K P V LKRF++ NG
Sbjct: 181 LGSALESFTRVEKL-DEQLTCDNCNEKVSKEKQLLLDKLPLVATFHLKRFKN--NGLYME 237
Query: 359 KLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVSKTEDGQW 417
K+ V+ PL ++L+P++ I++ + + Y L +V H G +V GHY++ ++ W
Sbjct: 238 KIYKHVKIPLEIDLQPYMRNIQENEV-STKYHLYALVEHFGYSVAYGHYSSYVRSAPKIW 296
Query: 418 FKFNDSVVTSVTEEQVLEQQAYLLFY 443
F+DS VT + E+ VL Q +Y+LFY
Sbjct: 297 HHFDDSKVTRIDEDMVLSQDSYILFY 322
>At2g24640 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 743
Score = 129 bits (324), Expect = 9e-30
Identities = 98/319 (30%), Positives = 149/319 (45%), Gaps = 25/319 (7%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGN 193
GL N G++CF + ++Q + V LL H C + C C + N
Sbjct: 228 GLTNCGNSCFANVVLQCLSWTRPLVAYLLERGHKREC--RRNDWCFLCEFE--------N 277
Query: 194 GPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGSSKA 253
S +N++S +I +L Q+DAHE +F ++ + + FG K
Sbjct: 278 HLDRANYSRFPFSPMNIISRLPNIGGNLGYGRQEDAHELMRFAIDMMQSVCLDEFGGEKV 337
Query: 254 --PDCQCIT--HRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNP-KLEDCLDHFQ 308
P Q T IF G L++ +QC+ C + +MDL++EI + LE+CLD F
Sbjct: 338 VPPRAQETTLIQYIFGGLLQSQVQCTACSNVSDQYENMMDLTVEIHGDAVSLEECLDQFT 397
Query: 309 REETLT-DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFP 367
+E L D Y+C C K+L++ APN+L I LKRF+ G+ KLN R+ FP
Sbjct: 398 AKEWLQGDNLYKCDRCDDYVKACKRLSIRCAPNILTIALKRFQ---GGRFGKLNKRISFP 454
Query: 368 LHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQ---GHYTTVSKTEDGQWFKFNDSV 424
+L P++ + + Y L V+ H ++ GHY K G W++ +DS
Sbjct: 455 ETFDLGPYMSGGGEG---SDVYKLYAVIVHLDMLNASFFGHYICYVKDFRGNWYRIDDSE 511
Query: 425 VTSVTEEQVLEQQAYLLFY 443
V V E VL Q+AY+L Y
Sbjct: 512 VEKVELEDVLSQRAYMLLY 530
>At4g24560 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 1008
Score = 128 bits (321), Expect = 2e-29
Identities = 93/320 (29%), Positives = 159/320 (49%), Gaps = 28/320 (8%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGN 193
GL+N+G++CF + + Q ++ P L H C K +C +C +++
Sbjct: 543 GLINVGNSCFANVVFQCLMFTPPLTTYFLQQFHSRACTKKE--QCFTCGFEKLVVK---- 596
Query: 194 GPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHT-----DHARVF 248
+ S +S LLS +I L ++DAHE+ +F+++ + + +
Sbjct: 597 --AKEEKSPLSPN--GLLSQLQNIGIFLGNGKEEDAHEFLRFVVDTMQSVCIKASEYDMT 652
Query: 249 GSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNN-PKLEDCLDHF 307
SSK D I F GYL++ ++C +C + +MDL++EI + L+D L F
Sbjct: 653 KSSKLEDTTLIG-LTFGGYLRSKIKCMKCQVKSELREKMMDLTVEIDGDISTLDDALRRF 711
Query: 308 QREETLT-DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQF 366
R E L + Y C SCK + K+L + + PNVL I LKRF+ G+ KLN ++F
Sbjct: 712 TRTEILDGENKYRCGSCKSYERAKKKLKITEPPNVLTIALKRFQ---AGKFGKLNKLIRF 768
Query: 367 PLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVD---QGHYTTVSKTEDGQWFKFNDS 423
P L+L P++ ++ + Y L V+ H ++ GHY + ++ +W+K +DS
Sbjct: 769 PETLDLAPYVSGGSEK---SHDYKLYGVIVHLDVMNAAFSGHYVCYIRNQN-KWYKADDS 824
Query: 424 VVTSVTEEQVLEQQAYLLFY 443
V + E++L + AY+LFY
Sbjct: 825 TVVTSDVERILTKGAYMLFY 844
>Hs22044555 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 489
Score = 127 bits (320), Expect = 3e-29
Identities = 91/329 (27%), Positives = 148/329 (44%), Gaps = 65/329 (19%)
Query: 120 KTELPASLHRDGL--QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTK 177
+ +LP S R GL NMG+TC++++ +Q + + P +LS +H C G
Sbjct: 65 REKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKG-- 122
Query: 178 CVSCALDEIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLL 237
C+ C + N PG H++HH ++
Sbjct: 123 CMLCTMQAHITRALHN-PG-------------------HVDHHSKDTT------------ 150
Query: 238 NQLHTDHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNN 297
+ H+IF GY ++ ++C C T DP +D++L+I+
Sbjct: 151 ---------------------LIHQIFGGYWRSQIKCLHCHRISDTFDPYLDIALDIQAA 189
Query: 298 PKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQ 356
++ L+ + E L + Y C C Q K LTLH + VL++ LKRF +
Sbjct: 190 QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNK 249
Query: 357 SAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVSKTEDG 415
AK VQ+P L+++P++ Q + + Y L V+ H G + GHY + K ++G
Sbjct: 250 IAK---NVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEG 303
Query: 416 QWFKFNDSVVTSVTEEQVLEQQAYLLFYI 444
QW+K +D+ VT+ + VL QQAY+LFYI
Sbjct: 304 QWYKMDDAEVTASSITSVLTQQAYVLFYI 332
>At5g65450 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 731
Score = 125 bits (313), Expect = 2e-28
Identities = 98/344 (28%), Positives = 160/344 (46%), Gaps = 25/344 (7%)
Query: 110 PASQWDTVMEKTELPASLHRDGLQ----GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHK 165
P+S D + EL L+ D ++ GLVN+G++C+ ++++Q + + L+
Sbjct: 302 PSSSIDEMSFSYELFVKLYCDRVELQPFGLVNLGNSCYANAVLQCLAFTRPLISYLIRGL 361
Query: 166 HCNNCDIKSGTKCVSCALDEIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSS 225
H C KS C C + + G S +S + +LS I HL
Sbjct: 362 HSKTCRKKSW--CFVCEFEHLILK------ARGGESPLSP--IKILSKLQKIGKHLGPGK 411
Query: 226 QQDAHEYWQFLLNQLHTDHARVF-GSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTI 284
++DAHE+ + ++ + + + + + + F GYL + ++C C
Sbjct: 412 EEDAHEFLRCAVDTMQSVFLKEAPAAGPFAEETTLVGLTFGGYLHSKIKCMACLHKSERP 471
Query: 285 DPIMDLSLEIKNN-PKLEDCLDHFQREETLT-DFHYECQSCKQNQGVVKQLTLHKAPNVL 342
+ +MDL++EI + LE+ L F E L + Y C CK Q K+L + + PN+L
Sbjct: 472 ELMMDLTVEIDGDIGSLEEALAQFTAYEVLDGENRYFCGRCKSYQKAKKKLMILEGPNIL 531
Query: 343 VIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSH---QG 399
+ LKRF+ G KL+ + FP L++ P++ + + + Y L VV H
Sbjct: 532 TVVLKRFQSDNFG---KLSKPIHFPELLDISPYMS--DPNHGDHPVYSLYAVVVHLDAMS 586
Query: 400 TVDQGHYTTVSKTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
T+ GHY KT DG WFK +DS V V E VL + AY+L Y
Sbjct: 587 TLFSGHYVCYIKTLDGDWFKIDDSNVFPVQLETVLLEGAYMLLY 630
>At2g22310 [O] KOG1864 Ubiquitin-specific protease
Length = 365
Score = 122 bits (307), Expect = 8e-28
Identities = 99/330 (30%), Positives = 148/330 (44%), Gaps = 46/330 (13%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGN 193
G N G+TC+ +S++Q + F E LL H N D + ++C D +
Sbjct: 24 GFENFGNTCYCNSVLQALYFCAPFREQLLEHYANNKADAEENL--LTCL-----ADLFSQ 76
Query: 194 GPGTGKSSSV--SKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQL----------- 240
K + V K FV L N QDAHE+ +LLN+L
Sbjct: 77 ISSQKKKTGVIAPKRFVQRLKKQ---NELFRSYMHQDAHEFLNYLLNELVEILEKETQAT 133
Query: 241 ------HTDHARVFGSSKAPDCQCI--------THRIFQGYLKNTLQCSQCGFSKTTIDP 286
+ ++ KAP + H+IFQG L N +C +C +
Sbjct: 134 KADNETSSSPEKIANVLKAPLANGVHKEPIVTWVHKIFQGILTNETRCLRCETVTARDET 193
Query: 287 IMDLSLEIKNNPKLEDCLDHFQREETL-TDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQ 345
+DLSL+I+ N + CL +F ETL + + C C Q K++ + K P++LVI
Sbjct: 194 FLDLSLDIEQNSSITSCLKNFSSTETLHAEDKFFCDKCCSLQEAQKRMKIKKPPHILVIH 253
Query: 346 LKRFEH-QLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGT-VDQ 403
LKRF++ + G+ KL+ RV FPL L L DEY+ +I Y L VV H G+ +
Sbjct: 254 LKRFKYMEQLGRYKKLSYRVVFPLELKLS----NTVDEYV-DIEYSLFAVVVHVGSGPNH 308
Query: 404 GHYTTVSKTEDGQWFKFNDSVVTSVTEEQV 433
GHY ++ K+ + W F+D V + E V
Sbjct: 309 GHYVSLVKSHN-HWLFFDDESVEIIEESAV 337
>Hs20548613 [O] KOG1864 Ubiquitin-specific protease
Length = 370
Score = 119 bits (299), Expect = 7e-27
Identities = 98/344 (28%), Positives = 158/344 (45%), Gaps = 51/344 (14%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGN 193
GLVN G+TC+ +S++Q + F E +L++K + ++C D F+
Sbjct: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLAYKS----QPRKKESLLTCLADL----FHSI 91
Query: 194 GPGTGKSSSVS-KGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLN-------------- 238
K + K F+ L N QQDAHE+ +LLN
Sbjct: 92 ATQKKKVGVIPPKKFITRLRKE---NELFDNYMQQDAHEFLNYLLNTIADILQEERKQEK 148
Query: 239 ---QLHTDHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIK 295
+L + ++ PD + H IFQG L N +C C + + +DLS++++
Sbjct: 149 QNGRLPNGNIDNENNNSTPDPTWV-HEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVE 207
Query: 296 NNPKLEDCLDHFQREETL-TDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEH--Q 352
N + CL F ETL +++ Y C+ C+ Q K++ + K P +L + LKRF++ Q
Sbjct: 208 QNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQ 267
Query: 353 LNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGT-VDQGHYTTVSK 411
L+ + KL+ RV FPL L L D P+ YDL+ VV H G+ ++GHY + K
Sbjct: 268 LH-RYTKLSYRVVFPLELRL---FNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVK 323
Query: 412 TEDGQWFKFNDSVVTSVTEEQVLE------------QQAYLLFY 443
+ D W F+D +V + + + E + Y+LFY
Sbjct: 324 SHD-FWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFY 366
>At5g57990 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 829
Score = 119 bits (299), Expect = 7e-27
Identities = 91/315 (28%), Positives = 144/315 (44%), Gaps = 48/315 (15%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDE-IACDFYG 192
GL N+G+TCF++S++Q + + L + H C + C CA+ + +
Sbjct: 108 GLQNLGNTCFLNSVLQCLTYTEPLAATLQTAAHQKYCHVAGF--CALCAIQKHVRTARQA 165
Query: 193 NGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGSSK 252
NG VS NL I+ + Q+DAHEY LL +H S+
Sbjct: 166 NGRILAPKDLVS----NLRC----ISRNFRNCRQEDAHEYMINLLECMHKCSLPSGVPSE 217
Query: 253 APDC--QCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQRE 310
+ D + + H+IF G L+ SQ S+ T ++D ++
Sbjct: 218 SSDAYRRSLVHKIFGGSLR-----SQRALSRFTAVELLDNGAKV---------------- 256
Query: 311 ETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHL 370
Y+C+ CKQ KQLT+ KAP VL + LKRFE +S K++ +V F +
Sbjct: 257 -------YQCERCKQKVKAKKQLTVSKAPYVLTVHLKRFEAH---RSEKIDRKVDFTSAI 306
Query: 371 NLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVSKTEDGQWFKFNDSVVTSVT 429
++KP + + N+ Y L V+ H G + GHY +T G W+ +D+ V V+
Sbjct: 307 DMKPF---VSGPHEGNLKYTLYGVLVHYGRSSHSGHYACFVRTSSGMWYSLDDNRVVQVS 363
Query: 430 EEQVLEQQAYLLFYI 444
E+ V Q+AY+LFY+
Sbjct: 364 EKTVFNQKAYMLFYV 378
>HsM7706755 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 381
Score = 118 bits (296), Expect = 2e-26
Identities = 98/380 (25%), Positives = 155/380 (40%), Gaps = 101/380 (26%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDF 190
G GL N+G+TCF+++++Q + + L DF
Sbjct: 26 GHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRR------------------------DF 61
Query: 191 YGNGPGTGKSSSVSKGFVNLLSASWHINH------------------HLVGSSQQDAHEY 232
PG G++ +++ F +++ A WH++ G SQQDA E+
Sbjct: 62 RQEVPGGGRAQELTEAFADVIGALWHLDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEF 121
Query: 233 WQFLLNQLHTDHAR-------VFGSSKAP------------------------------- 254
+ L+ +LH + R + + P
Sbjct: 122 LKLLMERLHLEINRRGRRAPPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLER 181
Query: 255 -DCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPK---------LEDCL 304
D + + +F G LK+ L+C CG+ TT + DLSL I PK L DC
Sbjct: 182 EDSKIVD--LFVGQLKSCLKCQACGYRSTTFEVFCDLSLPI---PKKGFAGGKVFLRDCF 236
Query: 305 DHFQREETLTDFHYE-CQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDR 363
+ F +EE L + C C+Q K+LT+ + P +LV+ L RF G K +
Sbjct: 237 NLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSAS-RGSIKKSSVG 295
Query: 364 VQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTEDGQWFKFNDS 423
V FPL + L + + Y L + +H G+V GHYT + + + G W +NDS
Sbjct: 296 VDFPLQ---RLSLGDFASDKAGSPVYQLYALCNHSGSVHYGHYTALCRCQTG-WHVYNDS 351
Query: 424 VVTSVTEEQVLEQQAYLLFY 443
V+ V+E QV + Y+LFY
Sbjct: 352 RVSPVSENQVASSEGYVLFY 371
>Hs12383078 [O] KOG1864 Ubiquitin-specific protease
Length = 366
Score = 118 bits (296), Expect = 2e-26
Identities = 99/345 (28%), Positives = 159/345 (45%), Gaps = 53/345 (15%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGN 193
GLVN G+TC+ +S++Q + F E++L++K K ++C D F+
Sbjct: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYK----AQQKKKENLLTCLADL----FHSI 87
Query: 194 GPGTGKSSSVS-KGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLN-------------- 238
K + K F++ L N QQDAHE+ +LLN
Sbjct: 88 ATQKKKVGVIPPKKFISRLRKE---NDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEK 144
Query: 239 ---QLHTDHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIK 295
+L + + P+ + H IFQG L N +C C + + +DLS++++
Sbjct: 145 QNGKLKNGNMNEPAENNKPELTWV-HEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVE 203
Query: 296 NNPKLEDCLDHFQREETL-TDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEH--Q 352
N + CL F ETL ++ Y C++C Q K++ + K P VL + LKRF++ Q
Sbjct: 204 QNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMVLALHLKRFKYMEQ 263
Query: 353 LNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIP-NIAYDLLNVVSHQGT-VDQGHYTTVS 410
L + KL+ RV FPL L LF + + + YDL+ VV H G+ ++GHY T+
Sbjct: 264 LR-RYTKLSYRVVFPLEL----RLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIV 318
Query: 411 KTEDGQWFKFNDSVVTSVTEEQVLE------------QQAYLLFY 443
K+ G W F+D +V + + + E + Y+LFY
Sbjct: 319 KSH-GFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFY 362
>YDR069c [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 926
Score = 117 bits (294), Expect = 3e-26
Identities = 109/378 (28%), Positives = 158/378 (40%), Gaps = 65/378 (17%)
Query: 124 PASLHRDGLQ---GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKS--GTKC 178
P S H L GL N+G++C+M+ IIQ I+ + L + + +I S G+K
Sbjct: 550 PTSSHNYDLDFAVGLENLGNSCYMNCIIQCILGTHELTQIFLDDSYAKHININSKLGSKG 609
Query: 179 VSCA-LDEIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLL 237
+ + Y K S+S + A +N +SQQD E+ QFLL
Sbjct: 610 ILAKYFARLVHMMYKEQVDGSKKISISP--IKFKLACGSVNSLFKTASQQDCQEFCQFLL 667
Query: 238 NQLHTD------------------------HARVFGSSK-----APDCQCITHRIFQGYL 268
+ LH D R+ S + D I +FQG
Sbjct: 668 DGLHEDLNQCGSNPPLKELSQEAEARREKLSLRIASSIEWERFLTTDFSVIVD-LFQGQY 726
Query: 269 KNTLQCSQCGFSKTTIDPIMDLSLEI-----KNNPKLEDCLDHFQREETL-TDFHYECQS 322
+ L+C C + TT P LS+ I +NN +EDC F + E L D + C
Sbjct: 727 ASRLKCKVCSHTSTTYQPFTVLSIPIPKKNSRNNITIEDCFREFTKCENLEVDEQWLCPH 786
Query: 323 CKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLFQ---- 378
C++ Q KQLT+ + P L++ LKRF++ LN K ND V +P L+L P
Sbjct: 787 CEKRQPSTKQLTITRLPRNLIVHLKRFDNLLN----KNNDFVIYPFLLDLTPFWANDFDG 842
Query: 379 -----IEDE------YIPNIAYDLLNVVSHQGTVDQGHYTT-VSKTEDGQWFKFNDSVVT 426
+ D+ IP Y+L V H GT+ GHYT V K W F+D+
Sbjct: 843 VFPPGVNDDELPIRGQIPPFKYELYGVACHFGTLYGGHYTAYVKKGLKKGWLYFDDTKYK 902
Query: 427 SV-TEEQVLEQQAYLLFY 443
V + + AY+LFY
Sbjct: 903 PVKNKADAINSNAYVLFY 920
>Hs6912742 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 565
Score = 117 bits (293), Expect = 3e-26
Identities = 96/377 (25%), Positives = 152/377 (39%), Gaps = 95/377 (25%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDF 190
G GL N+G+TCF+++++Q + + L DF
Sbjct: 210 GHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRR------------------------DF 245
Query: 191 YGNGPGTGKSSSVSKGFVNLLSASWHINH------------------HLVGSSQQDAHEY 232
PG G++ +++ F +++ A WH + G SQQDA E+
Sbjct: 246 RQEVPGGGRAQELTEAFADVIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEF 305
Query: 233 WQFLLNQLHTDHAR-------VFGSSKAP------------------------------- 254
+ L+ +LH + R + + P
Sbjct: 306 LKLLMERLHLEINRRGRRAPPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLER 365
Query: 255 -DCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIK------NNPKLEDCLDHF 307
D + + +F G LK+ L+C CG+ TT + DLSL I L DC + F
Sbjct: 366 EDSKIVD--LFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLF 423
Query: 308 QREETLTDFHYE-CQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQF 366
+EE L + C C+Q K+LT+ + P +LV+ L RF G K + V F
Sbjct: 424 TKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSAS-RGSIKKSSVGVDF 482
Query: 367 PLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTEDGQWFKFNDSVVT 426
PL + L + + Y L + +H G+V GHYT + + + G W +NDS V+
Sbjct: 483 PLQ---RLSLGDFASDKAGSPVYQLYALCNHSGSVHYGHYTALCRCQTG-WHVYNDSRVS 538
Query: 427 SVTEEQVLEQQAYLLFY 443
V+E QV + Y+LFY
Sbjct: 539 PVSENQVASSEGYVLFY 555
>At4g39910 [O] KOG1864 Ubiquitin-specific protease
Length = 371
Score = 117 bits (293), Expect = 3e-26
Identities = 96/333 (28%), Positives = 146/333 (43%), Gaps = 47/333 (14%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGN 193
G N G+TC+ +S++Q + F E LL + N + ++C D +
Sbjct: 24 GFENFGNTCYCNSVLQALYFCVPFREQLLEYYTSNKSVADAEENLMTCL-----ADLFSQ 78
Query: 194 GPGTGKSSSV--SKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQL----------- 240
K + V K FV L N QDAHE+ +LLN++
Sbjct: 79 ISSQKKKTGVIAPKRFVQRLKKQ---NELFRSYMHQDAHEFLNYLLNEVVDILEKEAKAT 135
Query: 241 HTDHARVFGSS--------KAPDCQCITHR---------IFQGYLKNTLQCSQCGFSKTT 283
T+H SS K P + H+ IFQG L N +C +C
Sbjct: 136 KTEHETSSSSSPEKIANGLKVPQANGVVHKEPIVTWVHNIFQGILTNETRCLRCETVTAR 195
Query: 284 IDPIMDLSLEIKNNPKLEDCLDHFQREETL-TDFHYECQSCKQNQGVVKQLTLHKAPNVL 342
+ +DLSL+I+ N + CL +F ETL + + C C Q K++ + K P++L
Sbjct: 196 DETFLDLSLDIEQNSSITSCLKNFSSTETLHAEDKFFCDKCCSLQEAQKRMKIKKPPHIL 255
Query: 343 VIQLKRFEH-QLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGT- 400
VI LKRF++ + G+ KL+ RV FPL L L + E ++ Y L VV H G+
Sbjct: 256 VIHLKRFKYIEQLGRYKKLSYRVVFPLELKLSNTV-----EPYADVEYSLFAVVVHVGSG 310
Query: 401 VDQGHYTTVSKTEDGQWFKFNDSVVTSVTEEQV 433
+ GHY ++ K+ + W F+D V + E V
Sbjct: 311 PNHGHYVSLVKSHN-HWLFFDDENVEMIEESAV 342
>YNL186w [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 792
Score = 112 bits (279), Expect = 1e-24
Identities = 99/384 (25%), Positives = 160/384 (40%), Gaps = 88/384 (22%)
Query: 133 QGLVNMGSTCFMSSIIQTIIHNP---YFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACD 189
+GL+N G TC+ ++ +Q ++H P +++ D+L K+ D VS L E +
Sbjct: 362 RGLLNHGVTCYTNAAVQAMLHIPSIQHYLFDILMGKY----DSTISKNSVSYTLAETSKK 417
Query: 190 FYGNGPGTGKSSSVSKGFVN---LLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHAR 246
+ +VS ++N L+S IN + Q+D+HEY+ L+++L D
Sbjct: 418 MW-LPVSKNPRKNVSASYINPKHLISRLDDINCMMSEWQQEDSHEYFMSLMSRLQEDSV- 475
Query: 247 VFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLD- 305
+ I + IF G LK + C CG T P DLSL +K KL+ D
Sbjct: 476 ---PKGHKLIESIIYDIFGGLLKQIVTCKSCGSISKTEQPFYDLSLHLKGKKKLDPNSDL 532
Query: 306 --------------------------------------------------HFQREETLTD 315
F E+++ D
Sbjct: 533 SSDSINGTSATTSTTTSNAATKPSLSSSSSVNLNNGSPFAAASDLSSANRRFSIEKSIKD 592
Query: 316 FH-------------YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNG-QSAKLN 361
F Y C+ C + VK ++ +AP L++ LK+F + NG S+K+
Sbjct: 593 FFNPELIKVDKEQKGYVCEKCHKTTNAVKHSSILRAPETLLVHLKKF--RFNGTSSSKMK 650
Query: 362 DRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVSKTEDGQWFKF 420
V +P+ L+L + E + +P + Y LL+VV H+G ++ GHY K DG W +
Sbjct: 651 QAVSYPMFLDLTEYC---ESKELP-VKYQLLSVVVHEGRSLSSGHYIAHCKQPDGSWATY 706
Query: 421 NDSVVTSVTEEQVL-EQQAYLLFY 443
+D + ++E VL E AY L Y
Sbjct: 707 DDEYINIISERDVLKEPNAYYLLY 730
>YER144c [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 805
Score = 112 bits (279), Expect = 1e-24
Identities = 104/382 (27%), Positives = 166/382 (43%), Gaps = 56/382 (14%)
Query: 111 ASQWDTVMEKTELPASLHRDGLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCN-- 168
+S T++ +++ L D + GL N+G+ C+M+ I+Q ++ V L + + N
Sbjct: 427 SSSRQTILNNSQV---LDLDLIVGLENIGNCCYMNCILQCLVGTHDLVRMFLDNTYLNFI 483
Query: 169 NCDIKSGTKCVSCALDEIACD-FYGNGPGTGKS-SSVSKGFVNLLSASWHINHHLVGSSQ 226
N D G+K + I + + +G T + ++ + HIN S Q
Sbjct: 484 NFDSSRGSKGLLAKNFAILVNNMHRHGAFTPPNVRTIPVQTIQFKKICGHINPMYSDSMQ 543
Query: 227 QDAHEYWQFLLNQLHTD--------HARVFGSSKAPDCQCITHR---------------- 262
QD E+ QFLL+ LH D H + + + ++ R
Sbjct: 544 QDCQEFCQFLLDGLHEDLNQNGSKKHLKQLSDEEERMREKMSIRKASALEWERFLLTDFS 603
Query: 263 ----IFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKN--NPKLEDCLDHFQREETL-TD 315
+FQG + LQC C + TT LS+ + + DC F + E L D
Sbjct: 604 AIIDLFQGQYASRLQCQVCEHTSTTYQTFSVLSVPVPRVKTCNILDCFREFTKCERLGVD 663
Query: 316 FHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPH 375
+ C C + Q KQL + + P L+I LKRF++Q+N K N VQ+P L+L P+
Sbjct: 664 EQWSCPKCLKKQPSTKQLKITRLPKKLIINLKRFDNQMN----KNNVFVQYPYSLDLTPY 719
Query: 376 LFQ------IEDEYIPN------IAYDLLNVVSHQGTVDQGHYTT-VSKTEDGQWFKFND 422
+ I +E IP Y L V H G++ GHYT+ V K W+ F+D
Sbjct: 720 WARDFNHEAIVNEDIPTRGQVPPFRYRLYGVACHSGSLYGGHYTSYVYKGPKKGWYFFDD 779
Query: 423 SVVTSVT-EEQVLEQQAYLLFY 443
S+ +T + + AY+LFY
Sbjct: 780 SLYRPITFSTEFITPSAYVLFY 801
>CE26210 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 357
Score = 111 bits (278), Expect = 2e-24
Identities = 99/341 (29%), Positives = 146/341 (42%), Gaps = 36/341 (10%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKS--GTKCVSCALDEIAC 188
G GL NMG+TCFMS+ +Q + P E + + +S G+K V A
Sbjct: 22 GAVGLFNMGNTCFMSATLQCLFQTPGLAEVFTKKVFVSKVNTQSRLGSKGVISAGFASLS 81
Query: 189 DFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTD----- 243
D NG T S F+ L S + + L Q DA E+ FLL+ LH D
Sbjct: 82 DMIWNGTFTAIRPS---RFLQLFSDT--VYQPLSDGRQHDASEFQIFLLDALHEDTNQAQ 136
Query: 244 --------HARVFGSSKAPD--------CQCITHRIFQGYLKNTLQCSQCGFSKTTIDPI 287
H + +A D +R+ + ++C CG S T +
Sbjct: 137 RISFEQNYHGGAGIAKEAADFLKKHYQFSLSPVNRLLGSITVSEIRCLTCGASSATFEEN 196
Query: 288 MDLSLEIKNNPK--LEDCL-DHFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVI 344
+S+EI +N L+ CL HF + + D + C CK+ + + L + P V++I
Sbjct: 197 TIISVEIPSNSSCSLDMCLRSHFSQTKLDGDSRWNCPKCKEPRASTRTSKLWQPPPVMII 256
Query: 345 QLKRFEHQLNGQSAKLNDRVQF-PLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQ 403
LKRF NG K V F +++P+L ++ P Y L H G ++
Sbjct: 257 HLKRFA-LFNGDFEKNTAAVTFETARFDVRPYLHEMAPAEKP--VYKLYAATLHNGRLNS 313
Query: 404 GHYTTV-SKTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
GHYT V S +W +F+DSVVT +V AY+LFY
Sbjct: 314 GHYTAVASHLRSDKWLRFDDSVVTPCENFKVDPSLAYILFY 354
>CE23922 [O] KOG1864 Ubiquitin-specific protease
Length = 410
Score = 110 bits (275), Expect = 4e-24
Identities = 100/348 (28%), Positives = 151/348 (42%), Gaps = 70/348 (20%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGN 193
GLVN G+TC+ +S+IQ + F E +L++K S V+C D F+
Sbjct: 28 GLVNFGNTCYCNSVIQALFFCRPFREKVLNYKQTLKKSGASKDNLVTCLADL----FHSI 83
Query: 194 GPGTGKSSSVS-KGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQL----------HT 242
+ +++ K F+ L N QQDAHE++ +L+N +
Sbjct: 84 ASQKRRVGTIAPKRFITKLKKE---NELFDNYMQQDAHEFFNYLINTISETLIQEKIAER 140
Query: 243 DHARVFGSSK--------AP-------------------------------DCQCITHRI 263
+ A G+ K AP D H I
Sbjct: 141 EKASRHGTLKKGNVTVNLAPATAGLPRSDEKGTSERNGGITVEGNEFLNKSDTTTWIHEI 200
Query: 264 FQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQREETLT-DFHYECQS 322
FQG L N +C C + + +DLS++++ N + CL F ETL D Y C++
Sbjct: 201 FQGILTNETRCLSCETVSSKDEDFLDLSIDVEQNTSISHCLRVFSETETLCGDQKYFCET 260
Query: 323 CKQNQGVVKQLTLHKAPNVLVIQLKRFE--HQLNGQSAKLNDRVQFPLHLNLKPHLFQIE 380
C Q K++ + K P +L + LKRF+ LN + KL+ RV FPL L LF +
Sbjct: 261 CSSKQEAQKRMRIKKPPQLLALHLKRFKFVEPLN-RHTKLSYRVVFPLEL----RLFNVS 315
Query: 381 D--EYIPNIAYDLLNVVSHQG-TVDQGHYTTVSKTEDGQWFKFNDSVV 425
D EY + YDL+ V H G T ++GHY T+ K+ + W F+D +V
Sbjct: 316 DDAEYGDRM-YDLVATVVHCGATPNRGHYITLVKS-NSFWLVFDDDIV 361
>CE11978 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 555
Score = 109 bits (272), Expect = 9e-24
Identities = 112/443 (25%), Positives = 168/443 (37%), Gaps = 93/443 (20%)
Query: 38 RTMRTMRCMDCGEISCGSTFICLQCGFCGCWNNNHFLDHSQKLGHIFGVNSSNGLVFCFR 97
+ ++ M C D SC C N++H L H H + + C R
Sbjct: 85 KKLKCMTCHDSVSFSCAHQDCINSLKSSCCKNSDHLLPHMAVHNHPPILYHDRKSILCTR 144
Query: 98 CGDF--MADLVAEIPASQWDTVMEKTELPASLHRDGLQGLVNMGSTCFMSSIIQTIIHNP 155
C + + + S D V ++T L GL G +N G+TC+M++++Q + H
Sbjct: 145 CMVYTPVKRFLTHTKFSTSDKVEQETRKMEPLAFRGLLGYLNFGNTCYMNAVLQLLGHCS 204
Query: 156 YFVE---DLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGNGPGTGKSSSVSKGFVNLLS 212
F + +L+ +NC + ALD + Y + P + LS
Sbjct: 205 PFTQYLIELIPPGGWSNCSHDIPKTAIQMALD--LRNMYSDFP------------LPYLS 250
Query: 213 ASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFG-------------------SSKA 253
W I +QQDA E+ + LL+ L D + A
Sbjct: 251 P-WKI------ITQQDASEFMRNLLDILDRDLKTCSEYHRTNTLIEMGNPEMDYAIAMNA 303
Query: 254 PDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIK------------------ 295
P + IFQG L+N +QC CGF TI+ +DLS+ I
Sbjct: 304 PHTKTAISAIFQGVLENQIQCHSCGFRSRTIENFLDLSIPIVGENEFEEMYASKKLDTPK 363
Query: 296 -----------------------NNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVK 331
N LE CLD F + TL D + Y C C+ K
Sbjct: 364 APCTSSNIEDGQDPGFLVHQGAFNKTSLESCLDRFFQNSTLQDDNQYSCSKCEVLVDATK 423
Query: 332 QLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDL 391
H+ P V++IQLKRF H + G S K+ V+FP L+ F YDL
Sbjct: 424 STKAHRLPEVIIIQLKRFRHTMFG-SCKVGKVVEFP----LRSQDFGRWTTSGEPALYDL 478
Query: 392 LNVVSHQG-TVDQGHYTTVSKTE 413
+ V H+G +++ GHY + + E
Sbjct: 479 VGFVVHEGRSLEFGHYVSYCRHE 501
>SPBC713.02c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1129
Score = 107 bits (267), Expect = 4e-23
Identities = 87/307 (28%), Positives = 140/307 (45%), Gaps = 24/307 (7%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDF 190
G GL N G+TC+M+S++Q++ F + + N+ S V+ AL + F
Sbjct: 228 GYVGLKNQGATCYMNSLLQSLFFTNIFRKTVYKIPTDNDDSRDS----VAYALQRV---F 280
Query: 191 YGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGS 250
Y S+ S W+ + Q D E+ + L + L
Sbjct: 281 YNLEKQREPVSTTEL----TRSFGWNSFDSFM---QHDIQEFNRVLQDNLEK-------K 326
Query: 251 SKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQRE 310
K + + + IF G +K+ ++C + + ++ D+ L +K LED +
Sbjct: 327 MKGTEVENALNDIFVGKMKSYVKCIDVNYESSRVEDFWDIQLNVKGMDTLEDSFRDAIQV 386
Query: 311 ETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQ-LNGQSAKLNDRVQFPLH 369
ETLT + Q K + PNVL +QLKRF++ L K+NDR +FPL
Sbjct: 387 ETLTGDNKYYAEGHGLQDAHKGIIFESLPNVLQLQLKRFDYDMLRDMMVKINDRHEFPLE 446
Query: 370 LNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTE-DGQWFKFNDSVVTSV 428
++L+P+L + D+ ++ Y L V+ H G + GHY + K E D WFKF+D VT
Sbjct: 447 IDLEPYLSETADKSESHV-YVLHGVLVHGGDLHGGHYYALIKPEKDSNWFKFDDDRVTRA 505
Query: 429 TEEQVLE 435
T ++VLE
Sbjct: 506 TIKEVLE 512
>Hs21265129 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 551
Score = 104 bits (260), Expect = 2e-22
Identities = 94/377 (24%), Positives = 148/377 (38%), Gaps = 109/377 (28%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDF 190
G GL N+G+TCF+++++Q + + L DF
Sbjct: 210 GHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRR------------------------DF 245
Query: 191 YGNGPGTGKSSSVSKGFVNLLSASWHINH------------------HLVGSSQQDAHEY 232
PG G++ +++ F +++ A WH + G SQQDA E+
Sbjct: 246 RQEVPGGGRAQELTEAFADVIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEF 305
Query: 233 WQFLLNQLHTDHAR-------VFGSSKAP------------------------------- 254
+ L+ +LH + R + + P
Sbjct: 306 LKLLMERLHLEINRRGRRAPPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLER 365
Query: 255 -DCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIK------NNPKLEDCLDHF 307
D + + +F G LK+ L+C CG+ TT + DLSL I L DC + F
Sbjct: 366 EDSKIVD--LFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLF 423
Query: 308 QREETLTDFHYE-CQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQF 366
+EE L + C C+Q K+LT+ + P +LV+ L RF G K + V F
Sbjct: 424 TKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSAS-RGSIKKSSVGVDF 482
Query: 367 PLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTEDGQWFKFNDSVVT 426
PL + + + A D G+V GHYT + + + G W +NDS V+
Sbjct: 483 PL-----------QRLSLGDFASD------KAGSVHYGHYTALCRCQTG-WHVYNDSRVS 524
Query: 427 SVTEEQVLEQQAYLLFY 443
V+E QV + Y+LFY
Sbjct: 525 PVSENQVASSEGYVLFY 541
>7292738 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1129
Score = 103 bits (258), Expect = 4e-22
Identities = 81/309 (26%), Positives = 137/309 (44%), Gaps = 28/309 (9%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDF 190
G GL N G+TC+M+S++QT+ YF L + + +K V +L + +
Sbjct: 239 GYVGLKNQGATCYMNSLLQTL----YFTNSLRLSVYRIPTEADDSSKSVGLSLQRVFHEL 294
Query: 191 -YGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFG 249
+G+ P K + S G+ L S H D E+ + LL++L +
Sbjct: 295 QFGDRPVGTKKLTKSFGWETLDSFMQH-----------DVQEFLRVLLDKLESKMKGTIL 343
Query: 250 SSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQR 309
P +F+G + + ++C ++ T + D+ L IK+ + + +
Sbjct: 344 EGTIPG-------LFEGKMSSYIKCKNVDYNSTRYETFYDIQLNIKDKKNIYESFQDYVA 396
Query: 310 EETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQ-LNGQSAKLNDRVQFPL 368
ETL + Q K + P VL + L RF++ + S K NDR +F
Sbjct: 397 PETLEGDNKYDAGVHGLQEASKGVIFTSFPPVLHLHLMRFQYDPVTDSSIKYNDRFEFYE 456
Query: 369 HLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTT-VSKTEDGQWFKFNDSVVTS 427
H+NL +L + E+ Y L V+ H G GHY ++ DG+WFKF+D VV+S
Sbjct: 457 HINLDRYLAESENTLAD---YVLHAVLVHSGDNHGGHYVVFINPKADGRWFKFDDDVVSS 513
Query: 428 VTEEQVLEQ 436
+++ +EQ
Sbjct: 514 CRKQEAIEQ 522
>SPCC188.08c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1108
Score = 102 bits (253), Expect = 2e-21
Identities = 84/309 (27%), Positives = 133/309 (42%), Gaps = 26/309 (8%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDF 190
G GL N G+TC+M+S++Q++ Y + + D G ++ AL +
Sbjct: 211 GYVGLKNQGATCYMNSLLQSL----YIIHAFRRIVYQIPTDSPQGKDSIAYALQRCFYNL 266
Query: 191 -YGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFG 249
+ N P + + S G+ +L S H D E+ + L + L
Sbjct: 267 QFMNEPVSTTELTKSFGWDSLDSFMQH-----------DVQEFNRVLQDNLER------- 308
Query: 250 SSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQR 309
S + + +F G +K+ + C F + D+ L +K LED + +
Sbjct: 309 SMRDTKVENALTNLFVGKMKSYIACVNVNFESARSEDYWDIQLNVKGMKNLEDSFRSYIQ 368
Query: 310 EETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLN-GQSAKLNDRVQFPL 368
ETL + Q K + P +L +QLKRFE+ K+NDR +FPL
Sbjct: 369 VETLEGDNCYFADTYGFQEAKKGVIFESFPPILHLQLKRFEYDFERDMMIKINDRYEFPL 428
Query: 369 HLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTE-DGQWFKFNDSVVTS 427
+ K L D+ N Y L V+ H G + GHY + KTE DG W+K++D+ VT
Sbjct: 429 EFDAKAFLSPEADQS-QNCEYVLYGVLVHSGDLHNGHYYALLKTEKDGPWYKYDDTRVTR 487
Query: 428 VTEEQVLEQ 436
T +VLE+
Sbjct: 488 ATLREVLEE 496
>At5g06600 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1115
Score = 102 bits (253), Expect = 2e-21
Identities = 87/316 (27%), Positives = 136/316 (42%), Gaps = 33/316 (10%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDF 190
G GL N G+TC+M+S++QT+ H PYF + + H + + T + AL +
Sbjct: 196 GFVGLKNQGATCYMNSLLQTLYHIPYFRKAVY---HMPTTENDAPTASIPLALQSLFYKL 252
Query: 191 YGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGS 250
N + ++K F W + Q D E + L +L
Sbjct: 253 QYNDTSVA-TKELTKSF------GWDTYDSFM---QHDVQELNRVLCEKLE-------DK 295
Query: 251 SKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQRE 310
K + ++F+G+ N ++C F T + DL L++K + D +
Sbjct: 296 MKGTVVEGTIQQLFEGHHMNYIECINVDFKSTRKESFYDLQLDVKGCKDVYASFDKYVEV 355
Query: 311 ETL---TDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQ-LNGQSAKLNDRVQF 366
E L +H E Q K + P VL +QLKRFE+ + K+NDR +F
Sbjct: 356 ERLEGDNKYHAEGHGL---QDAKKGVLFIDFPPVLQLQLKRFEYDFMRDTMVKINDRYEF 412
Query: 367 PLHLNLK----PHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGH-YTTVSKTEDGQWFKFN 421
PL L+L +L D + N+ Y L +V+ H G V GH Y + T QW+KF+
Sbjct: 413 PLELDLDREDGKYLSPDADRSVRNL-YTLHSVLVHSGGVHGGHYYAFIRPTLSDQWYKFD 471
Query: 422 DSVVTSVTEEQVLEQQ 437
D VT ++ LE+Q
Sbjct: 472 DERVTKEDLKRALEEQ 487
>At3g11910 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1124
Score = 102 bits (253), Expect = 2e-21
Identities = 86/314 (27%), Positives = 137/314 (43%), Gaps = 29/314 (9%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDF 190
G GL N G+TC+M+S++QT+ H PYF + + H + + T + AL +
Sbjct: 205 GFVGLKNQGATCYMNSLLQTLYHIPYFRKAVY---HMPTTENDAPTASIPLALQSLFYKL 261
Query: 191 YGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGS 250
N + ++K F W + Q D E + L +L
Sbjct: 262 QYNDTSVA-TKELTKSF------GWDTYDSFM---QHDVQELNRVLCEKLE-------DK 304
Query: 251 SKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQRE 310
K + ++F+G+ N ++C + T + DL L++K + D +
Sbjct: 305 MKGTVVEGTIQKLFEGHHMNYIECINVDYKSTRKESFYDLQLDVKGCKDVYASFDKYVEV 364
Query: 311 ETLT-DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQ-LNGQSAKLNDRVQFPL 368
E L D Y + Q K + P VL +QLKRFE+ + K+NDR +FPL
Sbjct: 365 ERLEGDNKYHAEG-HDLQDAKKGVLFIDFPPVLQLQLKRFEYDFMRDTMVKINDRYEFPL 423
Query: 369 HLNLK----PHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGH-YTTVSKTEDGQWFKFNDS 423
L+L +L D+ + N+ Y L +V+ H G V GH Y + T QW+KF+D
Sbjct: 424 QLDLDREDGRYLSPDADKSVRNL-YTLHSVLVHSGGVHGGHYYAFIRPTLSDQWYKFDDE 482
Query: 424 VVTSVTEEQVLEQQ 437
VT ++ LE+Q
Sbjct: 483 RVTKEDVKRALEEQ 496
>Hs18860907_1 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 622
Score = 102 bits (253), Expect = 2e-21
Identities = 79/303 (26%), Positives = 134/303 (44%), Gaps = 25/303 (8%)
Query: 129 RDGLQGLVNMGSTCFMSSIIQTIIHNPYFVEDL-LSHKHCNNCDIKSGTKCVSCALDEIA 187
++ GL N+G+TC++++ +Q N + L L C++ + G + +
Sbjct: 85 KNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQTI 144
Query: 188 CD----FYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTD 243
C+ + + + GFV L L QQDA E+ + ++ L
Sbjct: 145 CEHLQYLFALLQNSNRRYIDPSGFVKALG--------LDTGQQQDAQEFSKLFMSLLED- 195
Query: 244 HARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDC 303
K PD + I + F G C+QCG + +L L I+ + +L DC
Sbjct: 196 ---TLSKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHKQLTDC 252
Query: 304 LDHFQREETLT-DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFE-HQLNGQSAKLN 361
+ F +EE L D Y C++C+ Q +++ L P L +QL RF + G KLN
Sbjct: 253 ISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLN 312
Query: 362 DRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTT-VSKTEDGQWFK 419
+ F L+++P++ Y+ Y+L V+ H+G + GHY V + G+W+K
Sbjct: 313 TYIGFSEILDMEPYVEHKGGSYV----YELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYK 368
Query: 420 FND 422
FND
Sbjct: 369 FND 371
>Hs20472401 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1320
Score = 100 bits (249), Expect = 4e-21
Identities = 61/154 (39%), Positives = 89/154 (57%), Gaps = 12/154 (7%)
Query: 300 LEDCLDHFQREETLT-DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSA 358
L+ CL+ F R E L + + C CKQ++ KQL L + PNVL++QLKRF +
Sbjct: 1062 LDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVLIVQLKRFSFRSFIWRD 1121
Query: 359 KLNDRVQFPL-HLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTV-------- 409
K+ND V+FP+ +L+L ++E +P +YDL V++H G + GHYT
Sbjct: 1122 KINDLVEFPVRNLDLSKFCIGQKEEQLP--SYDLYAVINHYGGMIGGHYTACARLPNDRS 1179
Query: 410 SKTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
S+ D W F+DS VT+V E QV+ + AY+LFY
Sbjct: 1180 SQRSDVGWRLFDDSTVTTVDESQVVTRYAYVLFY 1213
Score = 63.2 bits (152), Expect = 8e-10
Identities = 66/252 (26%), Positives = 94/252 (37%), Gaps = 63/252 (25%)
Query: 115 DTVMEKTELPASLHRDGLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKS 174
D+V E+ E + G GLVN+G+TCFM+S+IQ+ + N + D H +I
Sbjct: 481 DSVEEEEEEEKKVCLPGFTGLVNLGNTCFMNSVIQS-LSNTRELRDFF-HDRSFEAEIN- 537
Query: 175 GTKCVSCALDEIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHH-------------- 220
Y N GTG ++ GF LL A W HH
Sbjct: 538 ----------------YNNPLGTGGRLAI--GFAVLLRALWKGTHHAFQPSKLKAIVASK 579
Query: 221 ---LVGSSQQDAHEYWQFLLNQLHTDHARV--------FGSSKAPDCQCITHR------- 262
G +Q DA E+ FLL+ LH D R+ S PD + +
Sbjct: 580 ASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPD-EVVAEEAWQRHKM 638
Query: 263 --------IFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQREETLT 314
+FQG K+ L C C T DP + L + + K+ +F RE
Sbjct: 639 RNDSFIVDLFQGQYKSKLVCPVCAKVSITFDPFLYLPVPLPQKQKVLPVF-YFAREPHSK 697
Query: 315 DFHYECQSCKQN 326
+ K+N
Sbjct: 698 PIKFLVSVSKEN 709
>SPBC1703.12 [O] KOG1864 Ubiquitin-specific protease
Length = 585
Score = 99.8 bits (247), Expect = 7e-21
Identities = 67/237 (28%), Positives = 115/237 (48%), Gaps = 14/237 (5%)
Query: 218 NHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQC 277
N + QQDAHE++ FLLN + +G+ H +F+G L + +C C
Sbjct: 188 NEAFRSTQQQDAHEFFNFLLNSVTETLDEYYGNHSDVMHPKWVHSLFEGTLTSETKCLTC 247
Query: 278 GFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLH 336
+ + +DLS++I+N+ + CL F E L+ + + C CK Q K++ +
Sbjct: 248 ENITSRDESFLDLSIDIENHTSVTSCLRSFSASEMLSSKNKFHCDVCKSLQEAEKRMKIK 307
Query: 337 KAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLF-QIEDEYIPNIAYDLLNVV 395
K P +L + LKRF++ ++ + +D++ + + + LF ED Y L +V+
Sbjct: 308 KLPKILSLHLKRFKY---NETQEGHDKLFYTIVFTNEMRLFTTTEDAENAERMYYLSSVI 364
Query: 396 SH-QGTVDQGHYTTVSKTEDGQWFKFNDSVVTSVTE--------EQVLEQQAYLLFY 443
H G +GHY ++ +T+ W F+D VT V E +Q + AY+LFY
Sbjct: 365 VHVGGGPHRGHYVSIVRTKTYGWVLFDDENVTPVNENYLQRFFGDQPGQATAYVLFY 421
>HsM18874088 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 942
Score = 99.8 bits (247), Expect = 7e-21
Identities = 58/147 (39%), Positives = 82/147 (55%), Gaps = 6/147 (4%)
Query: 300 LEDCLD-HFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSA 358
L+DCL F R+E D Y C+ CK+ + VK + P +L I LKRF H+L S
Sbjct: 569 LQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELM-FST 627
Query: 359 KLNDRVQFPLH-LNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTE-DGQ 416
K++ V FPL L+L+P F +D + YDLL+V+ H GT GHY + +
Sbjct: 628 KISTHVSFPLEGLDLQP--FLAKDSPAQIVTYDLLSVICHHGTASSGHYIAYCRNNLNNL 685
Query: 417 WFKFNDSVVTSVTEEQVLEQQAYLLFY 443
W++F+D VT V+E V +AY+LFY
Sbjct: 686 WYEFDDQSVTEVSESTVQNAEAYVLFY 712
>Hs22043041 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 959
Score = 99.8 bits (247), Expect = 7e-21
Identities = 86/341 (25%), Positives = 146/341 (42%), Gaps = 50/341 (14%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDF 190
G GL N G+TC+M+++ Q + P E LLS + T ++
Sbjct: 26 GFVGLRNGGATCYMNAVFQQLYMQPGLPESLLS--------VDDDTDNPDDSVFYQVQSL 77
Query: 191 YGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGS 250
+G+ + V + F + W N L QQDA+E++ L++Q+ ++ + G
Sbjct: 78 FGHLMESKLQYYVPENFWKIFKM-W--NKELYVREQQDAYEFFTSLIDQMD-EYLKKMGR 133
Query: 251 SKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQRE 310
+ I FQG + C C + M L+L + + LE LD F R
Sbjct: 134 DQ------IFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRG 187
Query: 311 ETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQL-NGQSAKLNDRVQFPL 368
E L + Y C+ CK+ + VK+ + P+VLVI L RF +G+S K +++++FP
Sbjct: 188 EVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPW 247
Query: 369 HLNLKPHLF--QIEDEYIPNIA-----------------------YDLLNVVSHQGTVDQ 403
LN++P+ + + Y+L+ V+ H G
Sbjct: 248 MLNMEPYTVSGMARQDSSSEVGENGRSVDQGGGGSPRKKVALTENYELVGVIVHSGQAHA 307
Query: 404 GHYTTVSKTE----DGQWFKFNDSVVTSV-TEEQVLEQQAY 439
GHY + K G+W+KFND+V+ ++ LE + +
Sbjct: 308 GHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECF 348
>Hs21489975 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 911
Score = 99.8 bits (247), Expect = 7e-21
Identities = 58/147 (39%), Positives = 82/147 (55%), Gaps = 6/147 (4%)
Query: 300 LEDCLD-HFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSA 358
L+DCL F R+E D Y C+ CK+ + VK + P +L I LKRF H+L S
Sbjct: 538 LQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELM-FST 596
Query: 359 KLNDRVQFPLH-LNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTE-DGQ 416
K++ V FPL L+L+P F +D + YDLL+V+ H GT GHY + +
Sbjct: 597 KISTHVSFPLEGLDLQP--FLAKDSPAQIVTYDLLSVICHHGTASSGHYIAYCRNNLNNL 654
Query: 417 WFKFNDSVVTSVTEEQVLEQQAYLLFY 443
W++F+D VT V+E V +AY+LFY
Sbjct: 655 WYEFDDQSVTEVSESTVQNAEAYVLFY 681
>Hs5730108 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 913
Score = 97.4 bits (241), Expect = 4e-20
Identities = 59/147 (40%), Positives = 81/147 (54%), Gaps = 6/147 (4%)
Query: 300 LEDCLD-HFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSA 358
LEDCL F +E D Y C+ CK+ + VK + + P +L I LKRF H++ S
Sbjct: 538 LEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVM-YSF 596
Query: 359 KLNDRVQFPLH-LNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTE-DGQ 416
K+N V FPL L+L+P L + I YDLL+V+ H GT GHY + +GQ
Sbjct: 597 KINSHVSFPLEGLDLRPFLAKECTSQI--TTYDLLSVICHHGTAGSGHYIAYCQNVINGQ 654
Query: 417 WFKFNDSVVTSVTEEQVLEQQAYLLFY 443
W++F+D VT V E V + Y+LFY
Sbjct: 655 WYEFDDQYVTEVHETVVQNAEGYVLFY 681
>Hs4759290 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 690
Score = 97.1 bits (240), Expect = 5e-20
Identities = 57/149 (38%), Positives = 89/149 (59%), Gaps = 5/149 (3%)
Query: 299 KLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQS 357
+L++C++ F ETL + + C SCKQ+Q K+L L P +L+I LKRF + +
Sbjct: 507 RLQECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWMLPEILIIHLKRFSYTKFSRE 566
Query: 358 AKLNDRVQFPLH-LNLKPHLFQIEDEYIPNI-AYDLLNVVSHQGTVDQGHYTTVSKTED- 414
KL+ V+FP+ L+ + Q ++E P + YDL+ V +H G + GHYTT + +D
Sbjct: 567 -KLDTLVEFPIRDLDFSEFVIQPQNESNPELYKYDLIAVSNHYGGMRDGHYTTFACNKDS 625
Query: 415 GQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
GQW F+D+ V+ V E Q+ + AY+LFY
Sbjct: 626 GQWHYFDDNSVSPVNENQIESKAAYVLFY 654
Score = 56.2 bits (134), Expect = 9e-08
Identities = 48/186 (25%), Positives = 71/186 (37%), Gaps = 26/186 (13%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDF 190
G+ GL N+G+TCFM+S +Q + + P E L++ + + ++ + + E D
Sbjct: 34 GICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFRNPLG-MKGEIAEAYADL 92
Query: 191 YGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGS 250
S V F N + H +G Q D+ E FLL+ LH D RV
Sbjct: 93 VKQAWSGHHRSIVPHVFKNKVG---HFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKK 149
Query: 251 SKAPDCQCI-------------THR---------IFQGYLKNTLQCSQCGFSKTTIDPIM 288
C H+ F G K+TL C CG T DP
Sbjct: 150 EYVELCDAAGRPDQEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFC 209
Query: 289 DLSLEI 294
LS+ +
Sbjct: 210 YLSVPL 215
>SPCC1494.05c [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 979
Score = 96.7 bits (239), Expect = 6e-20
Identities = 58/169 (34%), Positives = 95/169 (55%), Gaps = 7/169 (4%)
Query: 280 SKTTIDPIMDLSLEIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKA 338
SKT + D S E L DCLD F++ E L + + C +CK+ + KQ+ + +
Sbjct: 808 SKTILSDKKDDS-EDSRTITLNDCLDEFEKTEQLGEEDPWYCPTCKEFRQASKQMEIWRC 866
Query: 339 PNVLVIQLKRFEHQLNGQSAKLNDRVQFP---LHLNLKPHLFQIEDEYIPNIAYDLLNVV 395
P +L+ LKRF + + K++D V+FP L ++++ +++ ++ P + Y+L V
Sbjct: 867 PEILIFHLKRFSSERRFRD-KIDDLVEFPIDNLDMSMRTGSYKLSEKENPKLIYELYAVD 925
Query: 396 SHQGTVDQGHYTTVSKTED-GQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
+H G + GHYT +K D GQ++ F+DS VT V E+ + AYLLFY
Sbjct: 926 NHYGGLGGGHYTAFAKNPDNGQFYCFDDSRVTPVCPEETVTSAAYLLFY 974
Score = 58.5 bits (140), Expect = 2e-08
Identities = 48/189 (25%), Positives = 76/189 (39%), Gaps = 29/189 (15%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDF 190
G GL N+G+TC+M+S +Q + H + D + N +S + + I
Sbjct: 309 GTCGLSNLGNTCYMNSALQCLTHTRE-LRDFFTSDEWKNQVNESNPLGMGGQVASIFASL 367
Query: 191 YGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFG- 249
+ SS + F + NH +G QQD+ E+ FLL+ LH D R++
Sbjct: 368 IKSLYSPEHSSFAPRQFKATIGK---FNHSFLGYGQQDSQEFLAFLLDGLHEDLNRIYQK 424
Query: 250 ----------------SSKAPDC--------QCITHRIFQGYLKNTLQCSQCGFSKTTID 285
+ A +C + +FQG ++TL C C T D
Sbjct: 425 PYTSKPDLYEVDEEKIKNTAEECWRLHKLRNDSLIVDLFQGMYRSTLVCPVCNTVSITFD 484
Query: 286 PIMDLSLEI 294
P MDL+L +
Sbjct: 485 PFMDLTLPL 493
>CE23923 [O] KOG1864 Ubiquitin-specific protease
Length = 398
Score = 95.5 bits (236), Expect = 1e-19
Identities = 63/171 (36%), Positives = 92/171 (52%), Gaps = 13/171 (7%)
Query: 261 HRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQREETLT-DFHYE 319
H IFQG L N +C C + + +DLS++++ N + CL F ETL D Y
Sbjct: 186 HEIFQGILTNETRCLSCETVSSKDEDFLDLSIDVEQNTSISHCLRVFSETETLCGDQKYF 245
Query: 320 CQSCKQNQGVVKQLTLHKAPNVLVIQLKRFE--HQLNGQSAKLNDRVQFPLHLNLKPHLF 377
C++C Q K++ + K P +L + LKRF+ LN + KL+ RV FPL L LF
Sbjct: 246 CETCSSKQEAQKRMRIKKPPQLLALHLKRFKFVEPLN-RHTKLSYRVVFPLEL----RLF 300
Query: 378 QIED--EYIPNIAYDLLNVVSHQG-TVDQGHYTTVSKTEDGQWFKFNDSVV 425
+ D EY + YDL+ V H G T ++GHY T+ K+ + W F+D +V
Sbjct: 301 NVSDDAEYGDRM-YDLVATVVHCGATPNRGHYITLVKS-NSFWLVFDDDIV 349
>YMR304w [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1230
Score = 95.1 bits (235), Expect = 2e-19
Identities = 82/321 (25%), Positives = 138/321 (42%), Gaps = 41/321 (12%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYF----VEDLLSHKHCNNCDIKSGTKCVSCALDEI 186
G G N G+TC+++S++Q+ YF E H+ NN V AL
Sbjct: 203 GYVGFRNQGATCYLNSLLQSYFFTKYFRKLVYEIPTEHESPNNS--------VPLALQRA 254
Query: 187 ACDFYGNGPGTGKSSSVSKGFVNLL-SASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHA 245
FY + S + + L S W +Q D E + L+++L +
Sbjct: 255 ---FYQL-----QVSDIPLDTLELTRSFGWDTAESF---TQHDVQELNRILMDRLENN-- 301
Query: 246 RVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLD 305
K + + IF G +K+ ++C + ++ DL L +KN L++ D
Sbjct: 302 -----MKGTPVEGKLNEIFVGKMKSYIKCINVDYESARVEDFWDLQLNVKNFKNLQESFD 356
Query: 306 HFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLN-GQSAKLNDRV 364
++ E + + Q K + P VL +QLKRFE+ N Q K+ND+
Sbjct: 357 NYIEMELMNGENQYAAQDYGLQDAQKGVIFESFPPVLHLQLKRFEYDFNYDQMVKVNDKY 416
Query: 365 QFPLHLNLKPHL--------FQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKT-EDG 415
+FP ++L P + E++ Y+L V+ H G + GHY T+ K +
Sbjct: 417 EFPETIDLSPFVDKDVLKKTLDSENKDKNPYVYNLHGVLVHSGDISTGHYYTLIKPGVED 476
Query: 416 QWFKFNDSVVTSVTEEQVLEQ 436
QW++F+D V VT++QV ++
Sbjct: 477 QWYRFDDERVWRVTKKQVFQE 497
>Hs14149627 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 952
Score = 93.6 bits (231), Expect = 5e-19
Identities = 55/147 (37%), Positives = 89/147 (60%), Gaps = 5/147 (3%)
Query: 299 KLEDCLDHFQREETL-TDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQS 357
KL+DC++ F +E L + + C +CK++Q K+L L P VLV+ LKRF + +
Sbjct: 758 KLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSRYMRD 817
Query: 358 AKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKT-EDGQ 416
KL+ V FP++ +L F I P Y+L+ V +H G + GHYT +K +DG+
Sbjct: 818 -KLDTLVDFPIN-DLDMSEFLINPNAGP-CRYNLIAVSNHYGGMGGGHYTAFAKNKDDGK 874
Query: 417 WFKFNDSVVTSVTEEQVLEQQAYLLFY 443
W+ F+DS V++ +E+Q++ + AY+LFY
Sbjct: 875 WYYFDDSSVSTASEDQIVSKAAYVLFY 901
>YJL197w [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1254
Score = 93.2 bits (230), Expect = 7e-19
Identities = 60/151 (39%), Positives = 84/151 (54%), Gaps = 8/151 (5%)
Query: 300 LEDCLDHFQREETL--TDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQS 357
L+DCL F + E L TD Y C +CK+++ KQ+ L P++L+I LKRFE Q S
Sbjct: 964 LDDCLQLFSKPEILGLTDSWY-CPTCKEHRQATKQIQLWNTPDILLIHLKRFESQ-RSFS 1021
Query: 358 AKLNDRVQFPL-HLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTT-VSKTEDG 415
K++ V FP+ L+L ++ +D + YDL V +H G + GHYT V D
Sbjct: 1022 DKIDATVNFPITDLDLSRYVVYKDDP--RGLIYDLYAVDNHYGGLGGGHYTAYVKNFADN 1079
Query: 416 QWFKFNDSVVTSVTEEQVLEQQAYLLFYIIR 446
+W+ F+DS VT E + AYLLFYI R
Sbjct: 1080 KWYYFDDSRVTETAPENSIAGSAYLLFYIRR 1110
>7300926 [O] KOG1864 Ubiquitin-specific protease
Length = 424
Score = 92.8 bits (229), Expect = 9e-19
Identities = 62/200 (31%), Positives = 100/200 (50%), Gaps = 23/200 (11%)
Query: 261 HRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQREETL-TDFHYE 319
H IFQG L + +C C + + DL +++ N + CL F ETL +D ++
Sbjct: 225 HEIFQGILTSETRCLNCETVSSKDENFFDLQVDVDQNTSITHCLRCFSNTETLCSDNKFK 284
Query: 320 CQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEH--QLNGQSAKLNDRVQFPLHLNLKPHLF 377
C +C Q K++ + K P +L + LKRF++ Q N + K++ RV FPL L LF
Sbjct: 285 CDNCCSYQEAQKRMRVKKLPMILALHLKRFKYMEQFN-RHIKVSHRVVFPLEL----RLF 339
Query: 378 QIEDEYI-PNIAYDLLNVVSHQGT-VDQGHYTTVSKTEDGQWFKFNDSVVTSVTEEQVLE 435
D+ + P+ YDL VV H G+ ++GHY ++ K+ G W F+D +V + + +
Sbjct: 340 NTSDDAVNPDRLYDLTAVVIHCGSGPNRGHYISIVKSH-GLWLLFDDDMVDKIEASTIED 398
Query: 436 ------------QQAYLLFY 443
+ Y+LFY
Sbjct: 399 FYGLTSDIHKSSETGYILFY 418
>Hs4507853 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 963
Score = 91.7 bits (226), Expect = 2e-18
Identities = 54/157 (34%), Positives = 90/157 (56%), Gaps = 17/157 (10%)
Query: 295 KNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQL 353
K L DC++ F ETL + + C +CK++Q K+ L P +LV+ LKRF +
Sbjct: 773 KTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNR 832
Query: 354 NGQSAKLNDRVQFPLH-LNLKPHLFQIEDEYIPNIA-----YDLLNVVSHQGTVDQGHYT 407
+ KL+ V+FP+ LN+ E++ N++ YDL+ V +H G + GHYT
Sbjct: 833 YWRD-KLDTVVEFPIRGLNMS--------EFVCNLSARPYVYDLIAVSNHYGAMGVGHYT 883
Query: 408 TVSKTE-DGQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
+K + +G+W+ F+DS V+ +E+Q++ + AY+LFY
Sbjct: 884 AYAKNKLNGKWYYFDDSNVSLASEDQIVTKAAYVLFY 920
>Hs4507857 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1102
Score = 91.3 bits (225), Expect = 3e-18
Identities = 89/334 (26%), Positives = 144/334 (42%), Gaps = 46/334 (13%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDF 190
G GL N G+TC+M+S++QT+ +F L + + +K V AL + +
Sbjct: 212 GYVGLKNQGATCYMNSLLQTL----FFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYEL 267
Query: 191 YGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGS 250
+ G + ++K F W L Q D E + LL+ V
Sbjct: 268 QHSDKPVG-TKKLTKSF------GWET---LDSFMQHDVQELCRVLLD-------NVENK 310
Query: 251 SKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKL-EDCLDHFQR 309
K + ++F+G + + +QC + + + D+ L IK + E +D+
Sbjct: 311 MKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAV 370
Query: 310 EETLTDFHYEC--QSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQ-LNGQSAKLNDRVQF 366
E+ D Y+ ++ + VK LTL P VL +QL RF + Q+ K+NDR +F
Sbjct: 371 EQLDGDNKYDAGEHGLQEAEKGVKFLTL---PPVLHLQLMRFMYDPQTDQNIKINDRFEF 427
Query: 367 PLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTT-VSKTEDGQWFKFNDSVV 425
P L L L + + + N Y L V+ H G GHY ++ DG+W KF+D VV
Sbjct: 428 PEQLPLDEFLQKTDPKDPAN--YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVV 485
Query: 426 TSVTEEQVLEQ---------------QAYLLFYI 444
+ T+E+ +E AY+L YI
Sbjct: 486 SRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYI 519
>7302097 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2778
Score = 90.9 bits (224), Expect = 3e-18
Identities = 98/398 (24%), Positives = 156/398 (38%), Gaps = 91/398 (22%)
Query: 110 PASQWDTVMEKTELPASLHRDGLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNN 169
P +WD + P G GL N G+TC+M+S++Q + P +L
Sbjct: 1649 PLREWDYLPPVGARPTK----GFCGLKNAGATCYMNSVLQQLYMVPAVRVGILRAHGAAT 1704
Query: 170 CDIK--SGTKCVSCALDEIACDFYGNGPGTGKSSSVSKGFVNLLSASWHI---------N 218
D + SG D G G G+ S + V+L S+S I N
Sbjct: 1705 TDGEDFSGDS-----------DLTGGGLGSALFSGPASALVSLPSSSSTIEDGLHDVRKN 1753
Query: 219 HHLV------------GSS-------------------------QQDAHEYWQFLLNQLH 241
+H+V G S QQDA E++ LL L
Sbjct: 1754 YHVVILKHVQAIFAHLGHSALQYYVPRGLWTHFKLLGEPVNLREQQDAVEFFMSLLESLD 1813
Query: 242 TDHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLE 301
+ + G + + + G + C +C + +P S++I+N+ L
Sbjct: 1814 -EGLKALGQPQ------LMNATLGGSFSDQKICQECPHRYSKEEPFSVFSVDIRNHSSLT 1866
Query: 302 DCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSA-K 359
+ L+ + + E L Y C C + VK++ + K P VL IQLKRFE+ A K
Sbjct: 1867 ESLEQYVKGELLEGADAYHCDKCDKKVVTVKRVCVKKLPPVLAIQLKRFEYDYERVCAIK 1926
Query: 360 LNDRVQFPLHLNLKPH----LFQIEDEY----------IPNIAYDLLNVVSHQGTVDQGH 405
ND +FP L+++P+ L ++E E + Y+L +V H G GH
Sbjct: 1927 FNDYFEFPRILDMEPYTVSGLAKLEGEVVEVGDNCQTNVETTKYELTGIVVHSGQASGGH 1986
Query: 406 YTTVSKTEDG-----QWFKFNDSVVTSVTEEQVLEQQA 438
Y + +++ QW+KF+D VT + E +A
Sbjct: 1987 YFSYILSKNPANGKCQWYKFDDGEVTECKMHEDEEMKA 2024
>Hs14149817 [O] KOG1867 Ubiquitin-specific protease
Length = 712
Score = 90.5 bits (223), Expect = 5e-18
Identities = 103/410 (25%), Positives = 152/410 (36%), Gaps = 96/410 (23%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLL-----------SHKHCNNCDIKSGTKCV 179
G+ GL N+G+TC+M+S++Q + H F + L + + +C T V
Sbjct: 271 GVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTV 330
Query: 180 SCALDEIACDFYGNGPGTGKSSSVSKGFVN------------------------------ 209
++E C G + SS+S G
Sbjct: 331 VYQMNE--CQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTL 388
Query: 210 ----------------LLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGSSKA 253
+L + W + G +QQDA E+ LL+++ + S A
Sbjct: 389 FQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPA 448
Query: 254 --PDCQC--------ITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLE---------- 293
P Q + + IF G L + + C C TI+P DLSLE
Sbjct: 449 LIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGK 508
Query: 294 -IKNNPKL-EDCLDHFQREETLTDFHYECQSCKQNQG-----------VVKQLTLHKAPN 340
I + P L + L F E L Y C C + KQL + P
Sbjct: 509 DIASQPCLVTEMLAKFTETEALEGKIYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQ 568
Query: 341 VLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLFQ--IEDEYIPNIAYDLLNVVSHQ 398
VL + LKRF K+ V F LN++P+ + ++ YDL VV H
Sbjct: 569 VLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVMHH 628
Query: 399 GT-VDQGHYTTVS-KTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFYIIR 446
G GHYT +E G W NDS ++ T ++V + QAY+LFY R
Sbjct: 629 GKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQR 678
>At4g10590 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 937
Score = 89.7 bits (221), Expect = 8e-18
Identities = 55/147 (37%), Positives = 86/147 (58%), Gaps = 7/147 (4%)
Query: 300 LEDCLDHFQREETL-TDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSA 358
L CL+ F EE L D + C SCK+++ K+L L K P++LV LKRF + ++
Sbjct: 776 LFSCLEAFLAEEPLGPDDMWFCPSCKEHRQANKKLDLWKLPDILVFHLKRFTYSRYLKN- 834
Query: 359 KLNDRVQFPLH-LNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKT-EDGQ 416
K++ V FP+H L+L ++ D+ + Y+L V +H G + GHYT +K +D +
Sbjct: 835 KIDTFVNFPVHDLDLSKYVKNKNDQ---SYLYELYAVSNHYGGLGGGHYTAYAKLIDDNE 891
Query: 417 WFKFNDSVVTSVTEEQVLEQQAYLLFY 443
W+ F+DS V+SV E ++ AY+LFY
Sbjct: 892 WYHFDDSHVSSVNESEIKNSAAYVLFY 918
Score = 60.8 bits (146), Expect = 4e-09
Identities = 54/189 (28%), Positives = 77/189 (40%), Gaps = 29/189 (15%)
Query: 129 RDGLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIAC 188
+ GL GL N+G+TCFM+S +Q + H P VE L + DI C IA
Sbjct: 326 KGGLAGLSNLGNTCFMNSALQCLAHTPPIVEYFLQD---YSDDINRDNPLGMCGELAIAF 382
Query: 189 -DFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTD---- 243
D +G++S + F L+ G +Q D+ E FLL+ LH D
Sbjct: 383 GDLLKKLWSSGRNSVAPRAFKTKLA---RFAPQFSGYNQHDSQELLAFLLDGLHEDLNKV 439
Query: 244 ----HARVFGSSKAPDCQ--------------CITHRIFQGYLKNTLQCSQCGFSKTTID 285
+ + S PD + + + QG K+TL C CG T D
Sbjct: 440 KRKPYIELKDSDSRPDDEVAEELWNYHKARNDSVIVDVCQGQYKSTLVCPACGKISITFD 499
Query: 286 PIMDLSLEI 294
P M LS+ +
Sbjct: 500 PFMYLSVPL 508
>YER098w [O] KOG1864 Ubiquitin-specific protease
Length = 754
Score = 89.0 bits (219), Expect = 1e-17
Identities = 68/240 (28%), Positives = 119/240 (49%), Gaps = 30/240 (12%)
Query: 226 QQDAHEYWQFLLNQ----LHTDHARV-FGSSKAPDCQ--CITHRIFQGYLKNTLQCSQCG 278
QQDAHE+ FLLN + ++ R+ FG K + IT +F+G L N ++C C
Sbjct: 433 QQDAHEFLNFLLNDFSEYIQRNNPRMRFGPQKTDNSNDNFITD-LFKGTLTNRIKCLTCD 491
Query: 279 FSKTTIDPIMDLSLEIKNNPK--LEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTL 335
+ +P +D +E++ + + ++ L + + E L + + C C Q + + L
Sbjct: 492 NITSRDEPFLDFPIEVQGDEETDIQKMLKSYHQREMLNGVNKFYCNKCYGLQEAERMVGL 551
Query: 336 HKAPNVLVIQLKRFEHQLNGQS-AKLNDRVQFPLHLNLKPHLFQIEDEYIPNI--AYDLL 392
+ P++L + LKRF++ +S KL +++ +PL L+ + + ++ Y+L
Sbjct: 552 KQLPHILSLHLKRFKYSEEQKSNIKLFNKILYPLTLD-------VSSTFNTSVYKKYELS 604
Query: 393 NVVSHQGTVDQ-GHYTTVSKTEDGQWFKFNDSVVTSVTEEQVL--------EQQAYLLFY 443
VV H G+ Q GHY + + E W ++D V S+ EE VL + AY+LFY
Sbjct: 605 GVVIHMGSGPQHGHYVCICRNEKFGWLLYDDETVESIKEETVLQFTGHPGDQTTAYVLFY 664
>CE26241 [O] KOG1867 Ubiquitin-specific protease
Length = 664
Score = 89.0 bits (219), Expect = 1e-17
Identities = 81/325 (24%), Positives = 130/325 (39%), Gaps = 60/325 (18%)
Query: 133 QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLS------HKHCNNCDIKSGTKCVSCALDEI 186
+G+ N+G+TCFM++++Q + F E ++S + H G C DE
Sbjct: 378 RGMRNVGNTCFMNAVLQALASISEFREYIMSLSSLEDYIHDEKEPKNGGNYCY--LTDEY 435
Query: 187 ACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHAR 246
+ + + F A + G Q D+HE+ ++ ++ LHT+ +
Sbjct: 436 RKLLISQSARSFREPTAPNEF---REAFISVCPRFRGFRQHDSHEFMRYFMDSLHTEMRK 492
Query: 247 VFGSSKAPDCQCIT-HRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEI-----KNNPKL 300
PD + + F+G L++++ C C ID MDLSL+I + +L
Sbjct: 493 CRKLPGMPDDKHTPISKYFEGTLQSSVICQTCRNCSNKIDEFMDLSLDIPAQRNASKVRL 552
Query: 301 EDCLDHFQREETLTDFHY-ECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAK 359
DCL F + E L EC CK Q KQ+ + K P
Sbjct: 553 SDCLSTFFKLEMLEKGEKPECAKCKTKQTCSKQMFIRKLP-------------------- 592
Query: 360 LNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVSKTEDGQWF 418
+D Y L +++ H G GHY K +G+WF
Sbjct: 593 --------------------QDSDEAPCTYSLQSIIVHIGYGCGSGHYIAFGK-RNGRWF 631
Query: 419 KFNDSVVTSVTEEQVLEQQAYLLFY 443
+F+D+VV V E V +Q+AY+L Y
Sbjct: 632 QFDDTVVKGVDEAHVSKQKAYVLLY 656
>YBL067c [O] KOG1864 Ubiquitin-specific protease
Length = 688
Score = 88.6 bits (218), Expect = 2e-17
Identities = 63/223 (28%), Positives = 110/223 (49%), Gaps = 19/223 (8%)
Query: 227 QDAHEYWQFLLNQL----HTDHARVFGSSKAPDCQCITHR-----IFQGYLKNTLQCSQC 277
QDAHE++ FLLN+L ++ ++ S D + + +FQG L N ++C C
Sbjct: 432 QDAHEFFNFLLNELSEYIERENKKIAASDINSDSEPSKSKNFISDLFQGTLTNQIKCLTC 491
Query: 278 GFSKTTIDPIMDLSLEIKNNPK--LEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLT 334
+ +P +D +E++ + + +++ L + + E L + + C C Q + +
Sbjct: 492 DNITSRDEPFLDFPIEVQGDEETDIQEILKSYHQREMLNGSNKFYCDECCGLQEAERLVG 551
Query: 335 LHKAPNVLVIQLKRFEH-QLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLN 393
L + P+ L + LKRF++ + + KL + + +PL LN+ I + Y+L
Sbjct: 552 LKQLPDTLTLHLKRFKYSEKQNCNIKLFNNIHYPLTLNV---CSSINSKVCQK--YELAG 606
Query: 394 VVSHQGTVDQ-GHYTTVSKTEDGQWFKFNDSVVTSVTEEQVLE 435
+V H G Q GHY ++ K E W F+D V +V EE VLE
Sbjct: 607 IVVHMGGGPQHGHYVSLCKHEKFGWLLFDDETVEAVKEETVLE 649
>SPBC18H10.08c [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 438
Score = 88.6 bits (218), Expect = 2e-17
Identities = 87/357 (24%), Positives = 151/357 (41%), Gaps = 61/357 (17%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHC-NNCDIKS----GTKCVSCALDEIAC 188
GL N+G+TC+M+ ++Q + +L + N + K+ G K S +
Sbjct: 73 GLTNLGNTCYMNCVLQCLFACKDLTIPMLQGRGLLQNINTKNPLGTGGKITSAFFSLLQS 132
Query: 189 DFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTD-HARV 247
+G + S + F+ ++ + +N Q DA E+ F L++LH D ++
Sbjct: 133 VLLNHG----QRSISPRNFLEIVQS---LNRDFSIDGQCDAQEFLNFFLDKLHEDLNSNA 185
Query: 248 FGSSKAP---------------------------DCQCITHRIFQGYLKNTLQCSQCGFS 280
S AP + I F G L + QC CG +
Sbjct: 186 SRSPIAPLTEDQLSAREELPLSHFSHIEWNLHLRSNKSIVVNNFVGQLCSRTQCMTCGRT 245
Query: 281 KTTIDPIMDLSL---EIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLH 336
TT P L++ ++ + L++CL F E L + C CK + K + +
Sbjct: 246 STTFAPFTSLAIPIDDVSHVVSLQECLLKFSAPELLQGHDGWHCPVCKVQRSAKKVIMIS 305
Query: 337 KAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLK-------PHLFQIEDEYIPNIAY 389
K P L+IQ++RF+ + G+ ++ PL L+L+ P FQ YIP+ Y
Sbjct: 306 KLPEYLIIQIQRFKISVMGRK-----KIDTPLGLSLQIPSKMLVPPSFQSGIGYIPS-NY 359
Query: 390 DLLNVVSHQGTVDQGHYTTVSKTEDGQWFKFNDSVVTSV---TEEQVLEQQAYLLFY 443
+L + H G ++ GHY + + +W +DS+V +V T+ + +Y+LFY
Sbjct: 360 NLFAFICHYGQLENGHYIS-DVLFNNEWCHIDDSIVRTVGGITDLREDFSSSYILFY 415
>7303210 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 857
Score = 88.6 bits (218), Expect = 2e-17
Identities = 54/147 (36%), Positives = 84/147 (56%), Gaps = 6/147 (4%)
Query: 300 LEDCL-DHFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSA 358
L DC+ F +E D Y C+ C + + +K + P VL I LKRF + L+ S+
Sbjct: 277 LYDCMASFFSADELKGDNMYSCERCNKLRTGIKYSRVLTLPEVLCIHLKRFRNDLS-YSS 335
Query: 359 KLNDRVQFPLH-LNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSK-TEDGQ 416
K++ V FPL +++P++ + D Y+L +V+ H GTV GHYT ++ T +G+
Sbjct: 336 KISSDVYFPLEGFDMRPYIHK--DCKSEVAIYNLSSVICHHGTVGGGHYTCFARNTLNGK 393
Query: 417 WFKFNDSVVTSVTEEQVLEQQAYLLFY 443
W++F+D VT V+ E V QAY+LFY
Sbjct: 394 WYEFDDQFVTEVSSELVQSCQAYVLFY 420
>Hs22063256 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 675
Score = 88.2 bits (217), Expect = 2e-17
Identities = 55/167 (32%), Positives = 87/167 (51%), Gaps = 24/167 (14%)
Query: 300 LEDCLDHFQREETLT-DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSA 358
L++C + +EE L D ++C C+ Q + +L+L P++L+I LKRF Q+ +
Sbjct: 231 LDECFQFYTKEEQLAQDDAWKCPHCQVLQQGMVKLSLWTLPDILIIHLKRF-CQVGERRN 289
Query: 359 KLNDRVQFPLH-LNLKPHLFQ--------------------IEDEYIPNIAYDLLNVVSH 397
KL+ V+FPL LN+ PH+ Q + Y + YDL V +H
Sbjct: 290 KLSTLVKFPLSGLNMAPHVAQRSTSPEAGLGPWPSWKQPDCLPTSYPLDFLYDLYAVCNH 349
Query: 398 QGTVDQGHYTTVSKTE-DGQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
G + GHYT + DGQW+ ++DS V + E++V + AY+LFY
Sbjct: 350 HGNLQGGHYTAYCRNSLDGQWYSYDDSTVEPLREDEVNTRGAYILFY 396
>At4g10570 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 928
Score = 87.8 bits (216), Expect = 3e-17
Identities = 54/147 (36%), Positives = 87/147 (58%), Gaps = 7/147 (4%)
Query: 300 LEDCLDHFQREETL-TDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSA 358
L CL+ F EE L D + C SCK+++ K+L L K P++LV LKRF + ++
Sbjct: 755 LFSCLEAFLAEEPLGPDDMWFCPSCKEHRQANKKLDLWKLPDILVFHLKRFTYSRYLKN- 813
Query: 359 KLNDRVQFPLH-LNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKT-EDGQ 416
K++ V FP+H L+L + ++++ + Y+L V +H G + GHYT +K +D +
Sbjct: 814 KIDTFVNFPVHDLDLSKY---VKNKNGQSYLYELYAVSNHYGGLGGGHYTAYAKLIDDNK 870
Query: 417 WFKFNDSVVTSVTEEQVLEQQAYLLFY 443
W+ F+DS V+SV E ++ AY+LFY
Sbjct: 871 WYHFDDSHVSSVNESEIRNSAAYVLFY 897
Score = 58.2 bits (139), Expect = 2e-08
Identities = 54/206 (26%), Positives = 80/206 (38%), Gaps = 49/206 (23%)
Query: 129 RDGLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEI-A 187
+ GL GL N+G+TCFM+S +Q + H P VE L + ++C L+ I
Sbjct: 291 KGGLAGLSNLGNTCFMNSALQCLAHTPPIVEYFLQDYMLDTYMFYFLVMVLTCILNIILT 350
Query: 188 CDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLV-----------------GSSQQDAH 230
+F G ++ F +LL W + V G +Q D+
Sbjct: 351 LNFQG---------ELAIAFGDLLKKLWSSGRNAVAPRAFKTKLARFAPQFSGYNQHDSQ 401
Query: 231 EYWQFLLNQLHTD--------HARVFGSSKAPDCQ--------------CITHRIFQGYL 268
E FLL+ LH D + + S PD + + + QG
Sbjct: 402 ELLAFLLDGLHEDLNKVKRKPYIELKDSDSRPDDEVAEELWNYHKARNDSVIVDVCQGQY 461
Query: 269 KNTLQCSQCGFSKTTIDPIMDLSLEI 294
K+TL C CG T DP M LS+ +
Sbjct: 462 KSTLVCPVCGKISITFDPFMYLSVPL 487
>Hs22068900 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 909
Score = 87.4 bits (215), Expect = 4e-17
Identities = 58/166 (34%), Positives = 84/166 (49%), Gaps = 23/166 (13%)
Query: 300 LEDCLDHFQREETLT-DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSA 358
L C + +EE L D + C CKQ Q L+L P+VL+I LKRF + +
Sbjct: 155 LSQCFQLYTKEERLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQE-GDRRM 213
Query: 359 KLNDRVQFPLH-LNLKPHL-------FQIEDEYIP------------NIAYDLLNVVSHQ 398
KL + V+FPL L++ PH+ + + + P + YDL V +H
Sbjct: 214 KLQNMVKFPLTGLDMTPHVVKRSQSSWSLPSHWSPWRRPYGLGRDPEDYIYDLYAVCNHH 273
Query: 399 GTVDQGHYTTVSKTE-DGQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
GT+ GHYT K DG W+ F+DS V ++E++V Q AY+LFY
Sbjct: 274 GTMQGGHYTAYCKNSVDGLWYCFDDSDVQQLSEDEVCTQTAYILFY 319
>Hs11641425 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2563
Score = 86.3 bits (212), Expect = 9e-17
Identities = 85/374 (22%), Positives = 151/374 (39%), Gaps = 72/374 (19%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNC---DIKSGTKCVSCALDEIA 187
G GL N G+TC+M+S+IQ + P +L+ + + D+ K + + +
Sbjct: 1548 GFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPR 1607
Query: 188 CDFYG------NGPGTGKSSSVSKGFVNLLSASWHINHHLVGS----------------- 224
D +G + P K+ + + +L I HL S
Sbjct: 1608 DDVFGYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLW 1667
Query: 225 -------SQQDAHEYWQFLLNQLHTDHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQC 277
Q DA E++ L++ L + KA + ++ G + C C
Sbjct: 1668 GEPVNLREQHDALEFFNSLVDSLDE-------ALKALGHPAMLSKVLGGSFADQKICQGC 1720
Query: 278 GFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLH 336
+ L+++I+N+ L D L+ + + + L + Y C+ C + VK+L +
Sbjct: 1721 PHRYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIK 1780
Query: 337 KAPNVLVIQLKRFEHQLNGQSA-KLNDRVQFPLHLNLKPHLF------------------ 377
K P VL IQLKRF++ + A K ND +FP L+++P+
Sbjct: 1781 KLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLI 1840
Query: 378 ----QIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTEDG------QWFKFNDSVVT- 426
Q E E + Y L+ V+ H G GHY + +G +W+KF+D VT
Sbjct: 1841 QQSEQSESETAGSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGERNRWYKFDDGDVTE 1900
Query: 427 -SVTEEQVLEQQAY 439
+ +++ ++ Q +
Sbjct: 1901 CKMDDDEEMKNQCF 1914
>Hs11641423 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2547
Score = 86.3 bits (212), Expect = 9e-17
Identities = 85/374 (22%), Positives = 151/374 (39%), Gaps = 72/374 (19%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNC---DIKSGTKCVSCALDEIA 187
G GL N G+TC+M+S+IQ + P +L+ + + D+ K + + +
Sbjct: 1548 GFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPR 1607
Query: 188 CDFYG------NGPGTGKSSSVSKGFVNLLSASWHINHHLVGS----------------- 224
D +G + P K+ + + +L I HL S
Sbjct: 1608 DDVFGYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLW 1667
Query: 225 -------SQQDAHEYWQFLLNQLHTDHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQC 277
Q DA E++ L++ L + KA + ++ G + C C
Sbjct: 1668 GEPVNLREQHDALEFFNSLVDSLDE-------ALKALGHPAMLSKVLGGSFADQKICQGC 1720
Query: 278 GFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLH 336
+ L+++I+N+ L D L+ + + + L + Y C+ C + VK+L +
Sbjct: 1721 PHRYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIK 1780
Query: 337 KAPNVLVIQLKRFEHQLNGQSA-KLNDRVQFPLHLNLKPHLF------------------ 377
K P VL IQLKRF++ + A K ND +FP L+++P+
Sbjct: 1781 KLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLI 1840
Query: 378 ----QIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTEDG------QWFKFNDSVVT- 426
Q E E + Y L+ V+ H G GHY + +G +W+KF+D VT
Sbjct: 1841 QQSEQSESETAGSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGERNRWYKFDDGDVTE 1900
Query: 427 -SVTEEQVLEQQAY 439
+ +++ ++ Q +
Sbjct: 1901 CKMDDDEEMKNQCF 1914
>At3g49600_2 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1035
Score = 86.3 bits (212), Expect = 9e-17
Identities = 84/303 (27%), Positives = 130/303 (42%), Gaps = 34/303 (11%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGN 193
GL N+G+TC+ +SI+Q + N F E + S ++ + LD+IA +
Sbjct: 75 GLTNLGATCYANSILQCLYMNTAFREGVFS--------VEVHVLKQNPVLDQIA-RLFAQ 125
Query: 194 GPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGSSKA 253
+ KS S FV L L QQD HE+ LL+ L + + KA
Sbjct: 126 LHASQKSFVDSDAFVKTL--------ELDNGVQQDTHEFLTLLLSLL--ERCLLHSGVKA 175
Query: 254 PDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMD---LSLEIKNNPKLEDCL-DHFQR 309
+ I +F G + + CS+CG + D L L +K L+ L D+
Sbjct: 176 ---KTIVQDLFSGSVSHVTTCSKCGRDSEASSKMEDFYALELNVKGLKSLDASLNDYLSL 232
Query: 310 EETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKR--FEHQLNGQSAKLNDRVQFP 367
E+ D Y C SC + + L P V+ QLKR F + + K+ FP
Sbjct: 233 EQLNGDNQYFCGSCNARVDATRCIKLRTLPPVITFQLKRCIFLPKTTAKK-KITSSFSFP 291
Query: 368 LHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGT-VDQGHYTTVSKTE-DGQWFKFNDSVV 425
L++ L + + YDL V+ H+G+ V+ GHY K E G W++F+D V
Sbjct: 292 QVLDMGSRLAESSQN---KLTYDLSAVLIHKGSAVNSGHYVAHIKDEKTGLWWEFDDEHV 348
Query: 426 TSV 428
+ +
Sbjct: 349 SEL 351
>Hs20532433 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2555
Score = 85.5 bits (210), Expect = 1e-16
Identities = 86/374 (22%), Positives = 150/374 (39%), Gaps = 72/374 (19%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNC---DIKSGTKCVSCALDEIA 187
G GL N G+TC+M+S+IQ + P +L+ + + D+ K S + +
Sbjct: 1557 GFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPR 1616
Query: 188 CDFYG------NGPGTGKSSSVSKGFVNLLSASWHINHHLVGSS---------------- 225
D +G + P K+ + + +L I HL S
Sbjct: 1617 DDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLW 1676
Query: 226 --------QQDAHEYWQFLLNQLHTDHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQC 277
Q DA E++ L++ L + KA I ++ G + C C
Sbjct: 1677 GEPVNLREQHDALEFFNSLVDSLDE-------ALKALGHPAILSKVLGGSFADQKICQGC 1729
Query: 278 GFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLH 336
+ L+++I+N+ L D L+ + + + L + Y C+ C + VK+L +
Sbjct: 1730 PHRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIK 1789
Query: 337 KAPNVLVIQLKRFEHQLNGQSA-KLNDRVQFPLHLNLKPHLF------------------ 377
K P VL IQLKRF++ + A K ND +FP L++ P+
Sbjct: 1790 KLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELI 1849
Query: 378 ----QIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTEDGQ------WFKFNDSVVT- 426
Q ++E Y L+ V+ H G GHY + +G+ W+KF+D VT
Sbjct: 1850 EQKEQSDNETAGGTKYRLVGVLVHSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTE 1909
Query: 427 -SVTEEQVLEQQAY 439
+ +++ ++ Q +
Sbjct: 1910 CKMDDDEEMKNQCF 1923
>7291841 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1096
Score = 85.5 bits (210), Expect = 1e-16
Identities = 64/194 (32%), Positives = 91/194 (45%), Gaps = 50/194 (25%)
Query: 300 LEDCLDHFQREETLT-DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRF-EHQLNG-Q 356
LE CL+H+ + ETL+ + + C C+Q VVK L L P++LV+ KRF +HQ G Q
Sbjct: 528 LEQCLEHYTKAETLSAEDAWRCPHCQQYLPVVKTLGLWSLPDILVVHFKRFRQHQSKGPQ 587
Query: 357 SAKLNDRVQFPL-HLNLKPHLFQIEDEY-------------------------------- 383
+AKL V+FPL ++ PHL + E
Sbjct: 588 AAKLTTMVKFPLTAFDMSPHLARGVHESASSSLGMGTGIGLGLGLGSNPWKKARSVDSRS 647
Query: 384 --------IPNIAYDLLNVVSHQG-TVDQGHYTTVSKTE-DGQWFKFNDSVVTSV----T 429
+ YDL V HQG T++ GHYT K D QW+KF+D V+ V
Sbjct: 648 STLNSRCDAKDTRYDLYAVCYHQGDTLETGHYTAACKNPYDRQWYKFDDQRVSKVPEDDI 707
Query: 430 EEQVLEQQAYLLFY 443
E+ ++ +AY+LFY
Sbjct: 708 EQDIINNEAYMLFY 721
>Hs4759296 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2555
Score = 85.1 bits (209), Expect = 2e-16
Identities = 86/374 (22%), Positives = 150/374 (39%), Gaps = 72/374 (19%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNC---DIKSGTKCVSCALDEIA 187
G GL N G+TC+M+S+IQ + P +L+ + + D+ K S + +
Sbjct: 1557 GFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPR 1616
Query: 188 CDFYG------NGPGTGKSSSVSKGFVNLLSASWHINHHLVGSS---------------- 225
D +G + P K+ + + +L I HL S
Sbjct: 1617 DDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLW 1676
Query: 226 --------QQDAHEYWQFLLNQLHTDHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQC 277
Q DA E++ L++ L + KA I ++ G + C C
Sbjct: 1677 GEPVNLREQHDALEFFNSLVDSLDE-------ALKALGHPAILSKVLGGSFADQKICQGC 1729
Query: 278 GFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLH 336
+ L+++I+N+ L D L+ + + + L + Y C+ C + VK+L +
Sbjct: 1730 PHRFECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIK 1789
Query: 337 KAPNVLVIQLKRFEHQLNGQSA-KLNDRVQFPLHLNLKPHLF------------------ 377
K P VL IQLKRF++ + A K ND +FP L++ P+
Sbjct: 1790 KLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELI 1849
Query: 378 ----QIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTEDGQ------WFKFNDSVVT- 426
Q ++E Y L+ V+ H G GHY + +G+ W+KF+D VT
Sbjct: 1850 EQKEQSDNETAGGTKYRLVGVLVHSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTE 1909
Query: 427 -SVTEEQVLEQQAY 439
+ +++ ++ Q +
Sbjct: 1910 CKMDDDEEMKNQCF 1923
>At2g40930 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 914
Score = 83.2 bits (204), Expect = 7e-16
Identities = 51/144 (35%), Positives = 79/144 (54%), Gaps = 6/144 (4%)
Query: 303 CLDHFQREETLT-DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLN 361
CL+ F REE L D + C C + + K+L L + P VLVI LKRF + KL
Sbjct: 763 CLEAFLREEPLVPDEMWFCPQCNERRQASKKLDLWRLPEVLVIHLKRFSYS-RSMKHKLE 821
Query: 362 DRVQFPLH-LNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTT-VSKTEDGQWFK 419
V FP+H L+L ++ ++ P + Y+L + +H G + GHYT + +D +W+
Sbjct: 822 TFVNFPIHDLDLTKYVAN-KNLSQPQL-YELYALTNHYGGMGSGHYTAHIKLLDDSRWYN 879
Query: 420 FNDSVVTSVTEEQVLEQQAYLLFY 443
F+DS ++ + E+ V AY+LFY
Sbjct: 880 FDDSHISHINEDDVKSGAAYVLFY 903
>ECU03g0580 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 933
Score = 82.8 bits (203), Expect = 9e-16
Identities = 83/322 (25%), Positives = 141/322 (43%), Gaps = 49/322 (15%)
Query: 126 SLHRDGLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDE 185
S G GL N+G+TC+++S++Q + F D+ + + + E
Sbjct: 104 SKEETGYVGLRNLGATCYINSLMQALFSIAKFRNDVFG------LEPRGRVLLLQKLFKE 157
Query: 186 IACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHA 245
+ TG+ + FV ++ W + H+ QD HE+ + + L D
Sbjct: 158 MQ---------TGEHPVDTTDFV--VNNIWVDDVHV----HQDIHEFSKVFFDSLEKD-- 200
Query: 246 RVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKN------NPK 299
SK D + + QG L + +CG + + D+ +EI++ +
Sbjct: 201 -----SKRKD---VIEDMIQGELVTYIN-GKCGCVRRIKEKFQDIQVEIRDFFNNKLSSN 251
Query: 300 LEDCLDHFQREETLT-DFHYECQSCKQNQGVV---KQLTLHKAPNVLVIQLKRFEHQLN- 354
L++ L + + E L + Y C+ G+V K + P V+ I LKRF
Sbjct: 252 LQESLKRYVKSEILDGNNRYNCEK----HGLVDAKKGVMFSSLPPVMFILLKRFNVDFET 307
Query: 355 GQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIA-YDLLNVVSHQGTVDQGHYTTVSKTE 413
G K+ND +FP +++ P L + + A YDL +V+ H+G D+GH+ K
Sbjct: 308 GNGYKINDYFEFPDSIDMLPFLDRDSKRKEESDATYDLYSVIVHRGDHDEGHFYAYLKI- 366
Query: 414 DGQWFKFNDSVVTSVTEEQVLE 435
+G+W KFND+VVT E + LE
Sbjct: 367 NGRWLKFNDTVVTEAGEMEALE 388
>CE29636 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1119
Score = 82.8 bits (203), Expect = 9e-16
Identities = 50/146 (34%), Positives = 77/146 (52%), Gaps = 8/146 (5%)
Query: 300 LEDCLDHFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEH-QLNGQSA 358
LE C++ F ETL D +C C++ K +T+ K P L+I LKRFE + G+
Sbjct: 974 LEHCIEKFSCPETL-DAAIQCDRCEKKTMRDKVMTIWKLPKYLIIHLKRFEFLREQGRMG 1032
Query: 359 KLNDRVQFPL-HLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTEDGQW 417
K V FPL H + P + + + Y+ + + +H G + GH+ +K+ + +W
Sbjct: 1033 KCKRTVNFPLKHFDPAPFVDKPDGN-----TYECIALANHYGQLSCGHFIAYAKSNEDKW 1087
Query: 418 FKFNDSVVTSVTEEQVLEQQAYLLFY 443
ND V V+EE+V +Q AYLLFY
Sbjct: 1088 LLLNDCSVREVSEEEVDKQGAYLLFY 1113
>CE29635 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1116
Score = 82.8 bits (203), Expect = 9e-16
Identities = 50/146 (34%), Positives = 77/146 (52%), Gaps = 8/146 (5%)
Query: 300 LEDCLDHFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEH-QLNGQSA 358
LE C++ F ETL D +C C++ K +T+ K P L+I LKRFE + G+
Sbjct: 971 LEHCIEKFSCPETL-DAAIQCDRCEKKTMRDKVMTIWKLPKYLIIHLKRFEFLREQGRMG 1029
Query: 359 KLNDRVQFPL-HLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTEDGQW 417
K V FPL H + P + + + Y+ + + +H G + GH+ +K+ + +W
Sbjct: 1030 KCKRTVNFPLKHFDPAPFVDKPDGN-----TYECIALANHYGQLSCGHFIAYAKSNEDKW 1084
Query: 418 FKFNDSVVTSVTEEQVLEQQAYLLFY 443
ND V V+EE+V +Q AYLLFY
Sbjct: 1085 LLLNDCSVREVSEEEVDKQGAYLLFY 1110
>At1g32850 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 887
Score = 81.6 bits (200), Expect = 2e-15
Identities = 50/147 (34%), Positives = 85/147 (57%), Gaps = 7/147 (4%)
Query: 300 LEDCLDHFQREETL-TDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSA 358
L CL+ F EE L D + C CK+++ K+L L K P++LV LKRF + ++
Sbjct: 730 LFSCLEAFLAEEPLGPDDMWYCPGCKEHRQANKKLDLWKLPDILVFHLKRFTYSRYFKN- 788
Query: 359 KLNDRVQFPLH-LNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSK-TEDGQ 416
K++ V F +H L+L + +++E + Y+L + +H G + GHYT +K ++ +
Sbjct: 789 KIDTLVNFHIHDLDLSKY---VKNEDGQSYLYELYAISNHYGGLGGGHYTAYAKLMDETK 845
Query: 417 WFKFNDSVVTSVTEEQVLEQQAYLLFY 443
W+ F+DS V++V E ++ AY+LFY
Sbjct: 846 WYNFDDSRVSAVNESEIKTSAAYVLFY 872
Score = 65.1 bits (157), Expect = 2e-10
Identities = 55/193 (28%), Positives = 81/193 (41%), Gaps = 35/193 (18%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNP----YFVEDLLSHKHCNNCDIKSGTKCVSCALDEI 186
GL GL N+G+TCFM+S +Q + H P YF++D S + N G ++ A E+
Sbjct: 294 GLGGLQNLGNTCFMNSTLQCLAHTPPIVEYFLQDYRSDINAKNPLGMRGE--LAIAFGEL 351
Query: 187 ACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTD--- 243
+ +G T + F L+ G +Q D+ E FLL+ LH D
Sbjct: 352 LRKLWSSGQNT----VAPRAFKTKLA---RFAPQFSGYNQHDSQEMLAFLLDGLHEDLNK 404
Query: 244 -----HARVFGSSKAPDCQCITHR--------------IFQGYLKNTLQCSQCGFSKTTI 284
+ S PD + + +FQG K+TL C CG T
Sbjct: 405 VKRKPYIEAKDSDGRPDDEVAEEKWKYHKARNDSVIVDVFQGQYKSTLVCPDCGKISITF 464
Query: 285 DPIMDLSLEIKNN 297
DP M LSL + ++
Sbjct: 465 DPFMYLSLPLPSS 477
>CE16183 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1130
Score = 81.3 bits (199), Expect = 3e-15
Identities = 81/345 (23%), Positives = 138/345 (39%), Gaps = 55/345 (15%)
Query: 126 SLHRDGLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDE 185
S G GL N G+TC+M+SI+Q+ YF + + + + A+
Sbjct: 186 SKRHTGCIGLRNQGATCYMNSILQSF----YFTTGFRRAVYNMDVGTEPNESNIVLAMQR 241
Query: 186 IACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHA 245
+ + +++S+++ F W L +Q D E+ + LL+ L T
Sbjct: 242 VFYELQMASEAV-ETNSLTRAF------GW---DKLDAFNQHDVQEFCRVLLDNLET--- 288
Query: 246 RVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLD 305
++ G+S+ +F+G +K+ ++C + + + D+ L + LE +
Sbjct: 289 KMKGTSEEKSIP----NLFRGNMKSYIKCLDVDYESSRTESFYDVQLNVLGMDSLERAFE 344
Query: 306 HFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQ 365
+ E L D + Q K + + P +L +QL RF Q G K+N+R
Sbjct: 345 AYTTSEILDDENKYDAGDHGLQRAEKGVKFVELPPILHVQLMRF--QYCGVEQKINERFS 402
Query: 366 FPLHLNLK------PHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTT----------V 409
FP +NL P L + + Y L V+ H G GHY T V
Sbjct: 403 FPEKMNLASCCELGPMLTE------EDCVYSLHAVLVHSGEFHGGHYVTYINVNLHESAV 456
Query: 410 SKTEDGQWFKFNDSVVTSVTE----------EQVLEQQAYLLFYI 444
T +W KF+D VV+ T E+ + AY+L Y+
Sbjct: 457 DPTSSAKWCKFDDDVVSRTTTDDAIVSNFGGEKTMNSSAYMLVYV 501
>CE16182 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1133
Score = 81.3 bits (199), Expect = 3e-15
Identities = 81/345 (23%), Positives = 138/345 (39%), Gaps = 55/345 (15%)
Query: 126 SLHRDGLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDE 185
S G GL N G+TC+M+SI+Q+ YF + + + + A+
Sbjct: 186 SKRHTGCIGLRNQGATCYMNSILQSF----YFTTGFRRAVYNMDVGTEPNESNIVLAMQR 241
Query: 186 IACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHA 245
+ + +++S+++ F W L +Q D E+ + LL+ L T
Sbjct: 242 VFYELQMASEAV-ETNSLTRAF------GW---DKLDAFNQHDVQEFCRVLLDNLET--- 288
Query: 246 RVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLD 305
++ G+S+ +F+G +K+ ++C + + + D+ L + LE +
Sbjct: 289 KMKGTSEEKSIP----NLFRGNMKSYIKCLDVDYESSRTESFYDVQLNVLGMDSLERAFE 344
Query: 306 HFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQ 365
+ E L D + Q K + + P +L +QL RF Q G K+N+R
Sbjct: 345 AYTTSEILDDENKYDAGDHGLQRAEKGVKFVELPPILHVQLMRF--QYCGVEQKINERFS 402
Query: 366 FPLHLNLK------PHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTT----------V 409
FP +NL P L + + Y L V+ H G GHY T V
Sbjct: 403 FPEKMNLASCCELGPMLTE------EDCVYSLHAVLVHSGEFHGGHYVTYINVNLHESAV 456
Query: 410 SKTEDGQWFKFNDSVVTSVTE----------EQVLEQQAYLLFYI 444
T +W KF+D VV+ T E+ + AY+L Y+
Sbjct: 457 DPTSSAKWCKFDDDVVSRTTTDDAIVSNFGGEKTMNSSAYMLVYV 501
>Hs22044589 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 449
Score = 80.9 bits (198), Expect = 4e-15
Identities = 77/292 (26%), Positives = 126/292 (42%), Gaps = 35/292 (11%)
Query: 120 KTELPASLHRDGL--QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTK 177
+ +LP S R GL NMG+TC++++ +Q + + +LS +H C G
Sbjct: 182 REKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTTPLANYMLSREHSQTCHRHKG-- 239
Query: 178 CVSCALD-EIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFL 236
C+ C + I + G S +++ GF Q+DAHE+ F
Sbjct: 240 CMLCTMQAHITRALHNPGHVIQPSQALAAGFHR--------------GKQEDAHEFLMFT 285
Query: 237 LNQLHTDHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKN 296
++ + HA + G+S+ IT R K T DP +D++L+I+
Sbjct: 286 VDAMKK-HA-LPGTSR----WIITLRTPPSSTKYLEATGD--LKSNTFDPYLDIALDIQA 337
Query: 297 NPKLEDCLDHFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNG 355
++ L+ + E L + Y C C Q K LTLH + VL++ LKRF
Sbjct: 338 AQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGN 397
Query: 356 QSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHY 406
+ AK VQ+P L+++P++ + Y L V+ H G + GHY
Sbjct: 398 KIAK---NVQYPECLDMQPYMSHTN---TGPLVYVLYAVLVHAGWSCYNGHY 443
>CE03146 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1095
Score = 79.7 bits (195), Expect = 8e-15
Identities = 57/168 (33%), Positives = 82/168 (47%), Gaps = 18/168 (10%)
Query: 295 KNNPKLEDCLDHFQREETLT-DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQL 353
+ NP L LD F E L + + C +CK+N K+L L++ P VL+IQLKRF +
Sbjct: 905 ETNPHLTQMLDLFSETERLKPEESWYCSTCKENVEATKKLQLYRLPPVLIIQLKRFVYTA 964
Query: 354 NGQSAKLNDR------VQFPLH-LNLKPHLFQIEDEYIPN-IAYDLLNVVSHQGTVDQGH 405
+ + R V++PL L++ P F E PN YDL VV H G GH
Sbjct: 965 FTYQSSMARRSKDTRSVEYPLESLDMSP--FLAETSPHPNSTMYDLTGVVCHSGNSYFGH 1022
Query: 406 YTTVSKTEDG-------QWFKFNDSVVTSVTEEQVLEQQAYLLFYIIR 446
Y ++ + D +W F+DS V + + + AYLLFY +R
Sbjct: 1023 YISMGRLADFDSSKTKIEWRNFDDSTVARQSTSTLQTEDAYLLFYKMR 1070
>SPBC19C2.04c [O] KOG1867 Ubiquitin-specific protease
Length = 350
Score = 79.0 bits (193), Expect = 1e-14
Identities = 88/327 (26%), Positives = 147/327 (44%), Gaps = 48/327 (14%)
Query: 132 LQGLVNM-GSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDF 190
++GL N+ G+ CF++ ++Q++ +E L ++ + + L E+
Sbjct: 48 IKGLYNVSGNDCFLNCVLQSLASQESLLEIL---------KLRCSSSTLYATLYELLQKL 98
Query: 191 YGNGPGTGKSSSVSKG-FVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFG 249
+GPG + ++ G F+N L + N LV S QQDA E+ Q L+ L +
Sbjct: 99 -NSGPG----NPITPGSFLNSLEIA--TNKKLVRSIQQDAQEFLQHLVETLELQKPHTYK 151
Query: 250 SSKAPDCQCITHRIFQGYLKNTLQCSQC---GFSKTTIDPI-MDLSLEIKNNPKLEDC-L 304
SK + F G ++ +QC QC S +T I + L E N + L
Sbjct: 152 WSKVLSFPVDSP--FIGTMEQKVQCCQCLAISISYSTATSIQLCLPPEYSGNSNVSLLSL 209
Query: 305 DHFQREETLTDFHYECQSCKQNQ------GVVKQLTLHKAPNVLVIQLKRFEHQLNGQSA 358
RE+ ++D Y+C SC ++ ++ + P +L IQL+R + G +
Sbjct: 210 MEADREQHISD--YKCDSCFKSSPKHSKTSCIRTVDWKNPPTILQIQLERTSYTCQGLTR 267
Query: 359 KLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTEDGQWF 418
N + FP L LK + YI L ++++H G+V GHY + +D W+
Sbjct: 268 N-NVSISFPSKLILKN-----KHHYI------LRSLITHSGSVTYGHYLCY-RLQDDIWW 314
Query: 419 KFNDSVVTSVTEEQVLEQ--QAYLLFY 443
K NDS++T + + L Q A LLFY
Sbjct: 315 KANDSLITKSSLNEALSQTRSACLLFY 341
>SPCC16A11.12c [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 849
Score = 77.8 bits (190), Expect = 3e-14
Identities = 54/155 (34%), Positives = 80/155 (50%), Gaps = 12/155 (7%)
Query: 300 LEDCLDHFQREETLT--DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNG-- 355
LEDCL F + E L D Y C CK + K+L + + P +LVI L RF
Sbjct: 692 LEDCLLEFSKPEQLDLQDSWY-CPGCKAFRPATKRLEIWRLPKILVIHLNRFSGHGGDLR 750
Query: 356 QSAKLNDRVQFPLH-LNLKPHL--FQIEDEYIPN---IAYDLLNVVSHQGTVDQGHYTTV 409
+ K D V +P+ LNLK L F + E++ + + YDL V +H G + GHYT
Sbjct: 751 RRRKRRDLVVYPVFDLNLKQFLSPFIKDHEWLSSQKSMLYDLYAVDNHHGFMSNGHYTAY 810
Query: 410 SKTEDGQ-WFKFNDSVVTSVTEEQVLEQQAYLLFY 443
++ Q +FKF+D+ + + E ++ AY+LFY
Sbjct: 811 ARDASSQTFFKFDDTAICEIDPEDIVTSSAYVLFY 845
Score = 58.2 bits (139), Expect = 2e-08
Identities = 59/234 (25%), Positives = 90/234 (38%), Gaps = 65/234 (27%)
Query: 110 PASQWDTVMEKTELPASLHRD-GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCN 168
P +W + E +++++ GL GL N+G++C+M+S +Q +IH + LS
Sbjct: 255 PNGEWLSDSITKEQNLTINKEIGLCGLYNLGNSCYMNSALQCMIHTHELTKYFLS----- 309
Query: 169 NCDIKSGTKCVSCALDEIACDFYGNGPGTGKSSSVSKGFVNLLSASWH------------ 216
D D N P G V+ + +LL H
Sbjct: 310 ---------------DSYEKDINYNNP-LGMMGKVALSYASLLKMIHHTADMHSVSPSSF 353
Query: 217 ------INHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGSS--KAPDC------------ 256
N + G QQD+ E+ F L+ LH D R+ + PD
Sbjct: 354 KFIIGEFNTYFSGYRQQDSQEFIAFFLDGLHEDLNRIQIKPYFERPDLFDEHPLHVQRVA 413
Query: 257 -QC----------ITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPK 299
QC I ++FQG K+TL+CS C T DP M L+L + + K
Sbjct: 414 NQCWDIHTKRNDSIIVQLFQGMYKSTLECSICYQKSTAFDPFMYLTLPLPTSAK 467
>Hs10190742 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 922
Score = 77.4 bits (189), Expect = 4e-14
Identities = 76/293 (25%), Positives = 118/293 (39%), Gaps = 44/293 (15%)
Query: 112 SQWDTVMEKTELPASLHRDGLQ-GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHK---HC 167
SQ D K ++P H LQ G N+G+TC+M++++Q++ P F +DLL+
Sbjct: 263 SQGDPRCNKAQVPLDSHSQQLQQGFPNLGNTCYMNAVLQSLFAIPSFADDLLTQGVPWEY 322
Query: 168 NNCDIKSGTKCVSCALDEIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQ 227
+ T AL + C G V + S G+ Q
Sbjct: 323 IPFEALIMTLTQLLALKDF-CSTKIKRELLGNVKKVISAVAEIFS----------GNMQN 371
Query: 228 DAHEYWQFLLNQLHTDHARV--------------------FGSSKAPDCQCITHRIFQGY 267
DAHE+ L+QL D ++ GS+ C F+
Sbjct: 372 DAHEFLGQCLDQLKEDMEKLNATLNTGKECGDENSSPQMHVGSAATKVFVCPVVANFEFE 431
Query: 268 LKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPK-----LEDCLDHFQREETLTDFHYECQS 322
L+ +L C CG + ++P LS+ + K +++ LD F +EE L Y CQ
Sbjct: 432 LQLSLICKACGHAVLKVEPNNYLSINLHQETKPLPLSIQNSLDLFFKEEEL---EYNCQM 488
Query: 323 CKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPH 375
CKQ V + T + VL+I LKR+ K N++V P L+L +
Sbjct: 489 CKQKSCVARH-TFSRLSRVLIIHLKRYSFNNAWLLVKNNEQVYIPKSLSLSSY 540
>7295436 [O] KOG4598 Putative ubiquitin-specific protease
Length = 1248
Score = 77.0 bits (188), Expect = 5e-14
Identities = 65/265 (24%), Positives = 116/265 (43%), Gaps = 28/265 (10%)
Query: 116 TVMEKTELPASLHRDGLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSG 175
T E ASL G GLVN TC+++S++Q + P F L + N+ + K+
Sbjct: 71 TETEAEARQASLGPRGYVGLVNQAMTCYLNSLLQALFMTPEFRNALYRWEFDNDNEAKN- 129
Query: 176 TKCVSCALDEIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQF 235
+ L ++ + + +++ +++ F + +W Q D E +
Sbjct: 130 ---IPYQLQKLFLNLQTSPKAAVETTDLTRSFGWDSTEAW---------QQHDIQELCRV 177
Query: 236 LLNQLHTDHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIK 295
+ + L F ++K + + +++G + + ++C +C KT D +D+ L ++
Sbjct: 178 MFDALE----HKFKNTKQAN---LISNLYEGKMNDYVKCLECNTEKTREDTFLDIPLPVR 230
Query: 296 ------NNPKLEDCLDHFQREETLT-DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKR 348
+E+ L F + ETL + Y C+ CK+ K L P +L + LKR
Sbjct: 231 PFGSSSAYGSIEEALRAFVQPETLDGNNQYLCEKCKKKCDAHKGLHFKSFPYILTLHLKR 290
Query: 349 FEHQLNG-QSAKLNDRVQFPLHLNL 372
F+ KLNDRV FP LNL
Sbjct: 291 FDFDYQTMHRIKLNDRVTFPQTLNL 315
>Hs22045513 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 907
Score = 75.9 bits (185), Expect = 1e-13
Identities = 77/300 (25%), Positives = 127/300 (41%), Gaps = 49/300 (16%)
Query: 106 VAEIPASQWDTVMEKTELPASLHRDG-LQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSH 164
V ++ +Q T K +P S H+ LQG N+G+TC+M++I+Q++ F DLL
Sbjct: 241 VKKLRCNQDYTGWNKPRVPLSSHQQQQLQGFSNLGNTCYMNAILQSLFSLQSFANDLL-- 298
Query: 165 KHCNNCDIKSGTKCVSCALDEIACDFYG-----NGPGTGKSSSVSKGFVNLLSASWHINH 219
K G L+ + F + + + K N +SA+
Sbjct: 299 --------KQGIPWKKIPLNALIRRFAHLLVKKDICNSETKKDLLKKVKNAISAT---AE 347
Query: 220 HLVGSSQQDAHEYWQFLLNQLHTDHAR---------VFGSSKAPD--------CQCITHR 262
G Q DAHE+ L+QL D + V G +PD C IT+
Sbjct: 348 RFSGYMQNDAHEFLSQCLDQLKEDMEKLNKTWKTEPVSGEENSPDISATRAYTCPVITNL 407
Query: 263 IFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPK------LEDCLDHFQREETLTDF 316
F+ +++++ C CG + DLS+++ K ++D LD F R E L
Sbjct: 408 EFE--VQHSIICKACGEIIPKREQFNDLSIDLPRRKKPLPPRSIQDSLDLFFRAEEL--- 462
Query: 317 HYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLN-GQSAKLNDRVQFPLHLNLKPH 375
Y C+ C +V+ ++ P VL++ LKR+ + + K+ +V P +L L H
Sbjct: 463 EYSCEKCGGKCALVRH-KFNRLPRVLILHLKRYSFNVALSLNNKIGQQVIIPRYLTLSSH 521
>7292013_2 [O] KOG1871 Ubiquitin-specific protease
Length = 414
Score = 75.5 bits (184), Expect = 2e-13
Identities = 66/228 (28%), Positives = 103/228 (44%), Gaps = 24/228 (10%)
Query: 227 QDAHEYWQFLLNQLH---TDHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTT 283
+D + WQ + N + FG + D IF+G L++ LQ + S
Sbjct: 162 EDGGDVWQMICNNRNKGSVTRQTDFGRTPVSD-------IFRGELRSRLQ-REGEHSTDV 213
Query: 284 IDPIMDLSLEIKNNPKLEDCLDHFQREETLTDFHYECQSCKQNQGVV--KQLTLHKAPNV 341
I P L L I+ +++ L+ + L K Q VV +Q+TL K P V
Sbjct: 214 IQPFFTLQLNIEKAASVKEALEILVGRDQLEGV----TGSKTKQEVVAWQQMTLEKLPVV 269
Query: 342 LVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-T 400
L++ LK F+++ +G K+ +V FP+ L + + + AY L VV H G
Sbjct: 270 LILHLKYFDYRSDG-CTKILKKVDFPVELKIDAKILGSKKTSQKQRAYRLFAVVYHDGKE 328
Query: 401 VDQGHY-TTVSKTEDGQWFKFNDSVVTSVTEEQVLEQQA----YLLFY 443
+GHY T V T W +++DS V V+E+ VL+ YLL+Y
Sbjct: 329 ASKGHYITDVFHTGYSSWLRYDDSSVKPVSEKHVLQPHTPRVPYLLYY 376
>SPBP8B7.21 [O] KOG1871 Ubiquitin-specific protease
Length = 512
Score = 74.3 bits (181), Expect = 3e-13
Identities = 59/205 (28%), Positives = 93/205 (44%), Gaps = 25/205 (12%)
Query: 262 RIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNP--KLEDCLDHFQREETLTDFHYE 319
+IF G L++TL+ S ++P L L+I+ + D L+H E L ++H
Sbjct: 312 QIFGGQLRSTLRVPSARDS-VLLEPFQPLQLDIQAEDIHSVIDALEHMTAPEILPEWH-- 368
Query: 320 CQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLFQI 379
S K N KQ+ + P VL++ LKRF ++ +G + K + +P L++ ++F
Sbjct: 369 --SSKGNVTATKQMYIESLPPVLILHLKRFFYEASGGTQKNYKPIAYPARLSIPQNVFSP 426
Query: 380 EDEYIPNIAYDLLNVVSHQGT-VDQGHYTT-VSKTEDGQWFKFNDSVVTSVTEEQVLEQQ 437
+ YDL VV H GT GHYT V + + WF+ +D+ + V V +
Sbjct: 427 SVRGSIHPEYDLNAVVYHHGTSASGGHYTVDVQQLDKSGWFRIDDTHIHRVPIHDVENSE 486
Query: 438 ----------------AYLLFYIIR 446
AYLLFY R
Sbjct: 487 LSADPSLSKLGHGDRVAYLLFYTRR 511
>SPBC6B1.06c [O] KOG0944 Ubiquitin-specific protease UBP14
Length = 775
Score = 73.9 bits (180), Expect = 4e-13
Identities = 90/383 (23%), Positives = 153/383 (39%), Gaps = 78/383 (20%)
Query: 45 CMDCGEISCGSTFICLQCGFCGCWNNNHFLDHSQKLGHIFGVN----SSNGL--VFCFRC 98
C+ CG +SCG + G N H L H GH V S +G ++C+ C
Sbjct: 186 CLTCGALSCGRK------QYGGGGGNGHALSHYDDTGHPLAVKLKSISPDGQADIYCYSC 239
Query: 99 GDFMAD----------------------LVAEIPASQ---WDT-VMEKTELPASLHRDGL 132
+ D +AE+ Q WD E+ + L GL
Sbjct: 240 DEERIDPNIKTHMLNFGIDIAKLNKTEKSLAELQLEQNLNWDFGASEEDDASKRLFGPGL 299
Query: 133 QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYG 192
GL N+G++C+++S +Q++ F L+ + N ++ T + C L ++A
Sbjct: 300 TGLKNLGNSCYLASTMQSLFSIKEFAIHELNLFNTYNSVCQTPTTDLQCQLGKLA----- 354
Query: 193 NGPGTGKSSSVSK-GFVNLLSASW---------HINHHLVG--------SSQQDAHEYWQ 234
+G +GK S SK G +N S+S + +VG S QQDA+E+
Sbjct: 355 DGLVSGKFSKPSKIGLLNNPSSSILPYQDGLRPFMFKDVVGQGHSEFGTSQQQDAYEFLL 414
Query: 235 FLLNQLH------TDHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIM 288
+LL ++ TD ++F C++ + + Y + Q + I I
Sbjct: 415 YLLGKIRKSSIAKTDITKIFDFETEQKLSCLSCKRVR-YSSFSSQGLTLTVPRVKIGEIE 473
Query: 289 DLSLEIKNNPKLEDCLDHFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKR 348
+I ++ CLD + + + Y C++CK G + P VL++Q R
Sbjct: 474 --GEQIYEEVSIDQCLDATIQPDQM---EYTCEACKSKLGATTTTAMKSFPKVLILQANR 528
Query: 349 FEHQLNGQSAKLNDRVQFPLHLN 371
F+ L G K ++ P+ +N
Sbjct: 529 FD--LQGYQVK---KLSIPIIVN 546
>Hs5454156 [O] KOG1873 Ubiquitin-specific protease
Length = 823
Score = 73.2 bits (178), Expect = 7e-13
Identities = 57/189 (30%), Positives = 79/189 (41%), Gaps = 47/189 (24%)
Query: 300 LEDCLDHFQREETLTDFH-YECQSCKQNQ-----------------GVVKQLTLHKAPNV 341
++ CL F R E L D + C+ C + Q KQ+ + AP V
Sbjct: 633 IQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPPV 692
Query: 342 LVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLF----QIEDEYIPNIAYDLLNVVSH 397
L + LKRF+ Q K+N ++FP L+L P + +E + Y L VV H
Sbjct: 693 LTLHLKRFQ-QAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEENT-RVLYSLYGVVEH 750
Query: 398 QGTVDQGHYTTVSKTED-----------------------GQWFKFNDSVVTSVTEEQVL 434
GT+ GHYT +K GQWF +D+ V +V +VL
Sbjct: 751 SGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVL 810
Query: 435 EQQAYLLFY 443
QAYLLFY
Sbjct: 811 NSQAYLLFY 819
>7303452 [O] KOG1864 Ubiquitin-specific protease
Length = 852
Score = 73.2 bits (178), Expect = 7e-13
Identities = 55/197 (27%), Positives = 90/197 (44%), Gaps = 16/197 (8%)
Query: 262 RIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKN--------NPKLEDCLDHFQREETL 313
+ F G L T +C CG+ D +L L + N ++D ++++ E L
Sbjct: 543 KTFAGKLSTTYRCLNCGWESRNEDSFRELQLSFPDDKEDCGATNYSVQDLIEYYCSPEKL 602
Query: 314 T-DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEH-QLNGQSAKLNDRVQFPLHLN 371
D Y C CK+ + + + +AP L++ LK+F++ Q KL +V +
Sbjct: 603 DGDNQYFCPQCKKLCDAERHIGVTQAPKNLILTLKQFKYDQKYHFRTKLMHKVFHDESVT 662
Query: 372 LKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTTVSKTEDGQWFKFNDSVVTSVTE 430
+K E + + YDL V H G ++D GHY T + + W+KFND+VVT
Sbjct: 663 VKMSAKDSLQE-MSTVHYDLYAGVVHAGYSMDSGHYFTFAADQAKNWYKFNDNVVTHSKP 721
Query: 431 EQV----LEQQAYLLFY 443
E++ Y+LFY
Sbjct: 722 EEMHNLTSPNTPYILFY 738
>Hs22067085 [O] KOG1871 Ubiquitin-specific protease
Length = 798
Score = 72.8 bits (177), Expect = 1e-12
Identities = 54/192 (28%), Positives = 93/192 (48%), Gaps = 15/192 (7%)
Query: 263 IFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNP--KLEDCLDHFQREETLTDFHYEC 320
IF G++++ + Q T+ P L L+I+++ ++D L+ E++ +
Sbjct: 605 IFGGHIRSVVY-QQSSKESATLQPFFTLQLDIQSDKIRTVQDALESLVARESVQGY---T 660
Query: 321 QSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLFQ-- 378
KQ + +++TL K P VLV+ LKRF ++ G KL +++P+ L + L
Sbjct: 661 TKTKQEVEISRRVTLEKLPPVLVLHLKRFVYEKTGGCQKLIKNIEYPVDLEISKELLSPG 720
Query: 379 -IEDEYIPNIAYDLLNVVSHQG-TVDQGHYTT-VSKTEDGQWFKFNDSVVTSVTEEQVL- 434
+ + Y L VV H G + GHYTT V + W + +D V + + QV+
Sbjct: 721 VKNKNFKCHRTYRLFAVVYHHGNSATGGHYTTDVFQIGLNGWLRIDDQTVKVINQYQVVK 780
Query: 435 ---EQQAYLLFY 443
E+ AYLL+Y
Sbjct: 781 PTAERTAYLLYY 792
>Hs21361749 [O] KOG1867 Ubiquitin-specific protease
Length = 640
Score = 72.8 bits (177), Expect = 1e-12
Identities = 94/378 (24%), Positives = 133/378 (34%), Gaps = 96/378 (25%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLS----------HKHCNNCDIKSGTKCVS 180
G+ GL N+G+TC+M+SI+Q + H F E L+ K N SG S
Sbjct: 251 GVTGLRNLGNTCYMNSILQVLSHLQKFRECFLNLDPSKTEHLFPKATNGKTQLSGKPTNS 310
Query: 181 CALD-------EIACDFYG-----------------NGPGTGKSSSVSKGFVNLLSASWH 216
A + AC+ G N + K S+ + L W
Sbjct: 311 SATELSLRNDRAEACEREGFCWNGRASISRSLELIQNKEPSSKHISLCRELHTLFRVMWS 370
Query: 217 INHHLV-----------------GSSQQDAHEYWQFLLNQLHTD------HARV---FGS 250
LV G QQDA E+ LL+++ + R+ F
Sbjct: 371 GKWALVSPFAMLHSVWSLIPAFRGYDQQDAQEFLCELLHKVQQELESEGTTRRILIPFSQ 430
Query: 251 SK-APDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEI--------------- 294
K + + IF G L + + C C + TI+P DLSLE
Sbjct: 431 RKLTKQVLKVVNTIFHGQLLSQVTCISCNYKSNTIEPFWDLSLEFPERYHCIEKGFVPLN 490
Query: 295 KNNPKLEDCLDHFQREETLTDFHYECQSCKQNQ-----------GVVKQLTLHKAPNVLV 343
+ L + L F E L Y C C + KQL +++ P VL
Sbjct: 491 QTECLLTEMLAKFTETEALEGRIYACDQCNSKRRKSNPKPLVLSEARKQLMIYRLPQVLR 550
Query: 344 IQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPH-----LFQIEDEYIPNIAYDLLNVVSHQ 398
+ LKRF K+ V F L ++P+ L ++ E AYDL VV H
Sbjct: 551 LHLKRFRWSGRNHREKIGVHVVFDQVLTMEPYCCRDMLSSLDKE---TFAYDLSAVVMHH 607
Query: 399 GT-VDQGHYTTVSKTEDG 415
G GHYT +G
Sbjct: 608 GKGFGSGHYTAYCYNTEG 625
>At1g04860 [O] KOG1873 Ubiquitin-specific protease
Length = 961
Score = 71.6 bits (174), Expect = 2e-12
Identities = 43/122 (35%), Positives = 66/122 (53%), Gaps = 10/122 (8%)
Query: 331 KQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYD 390
K++ ++KAP VL I LKRF L G+ +KLN V F ++L+ ++ P + Y
Sbjct: 834 KKVLINKAPPVLTIHLKRFSQDLRGRLSKLNGHVAFKEVIDLRQYMDSRCSGEDPPV-YR 892
Query: 391 LLNVVSHQGTVDQGHYTT-------VSKTEDGQ--WFKFNDSVVTSVTEEQVLEQQAYLL 441
L +V H GT+ GHY V +T+ W+ +D+ V V+ E+VL +AY+L
Sbjct: 893 LAGLVEHSGTMRGGHYVAYVRGGQRVKETDSSSTAWYNVSDAYVRQVSLEKVLHSEAYIL 952
Query: 442 FY 443
FY
Sbjct: 953 FY 954
>ECU07g0410 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 295
Score = 69.7 bits (169), Expect = 8e-12
Identities = 81/321 (25%), Positives = 131/321 (40%), Gaps = 48/321 (14%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGN 193
GL N G+TCF +S +Q I+ + +L + N D K +S A + ++
Sbjct: 14 GLRNKGNTCFFNSAMQCILS----IGEL--NTFYKNTDFPRD-KPISNAFKQFIAEYETP 66
Query: 194 GPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLH--TDHARVFGSS 251
G KS F++ LS L QQD+HE+ ++ LH +D + S
Sbjct: 67 GCHDPKS------FIDKLSG----RIKLFNGMQQDSHEFLIQFIDLLHNESDGNKSRLES 116
Query: 252 KAPDCQCITHRIFQGYL----KNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHF 307
K + H + L K L C C +S TI M+ ++ ++ ++ +D +
Sbjct: 117 KDEFEEVRKHSLVAKTLFSMDKQVLTCEACNYSSVTI--AMNSTILVEPYETVQLGIDRY 174
Query: 308 QREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQ--LNGQSAKLNDRV 364
E L + C C + + K++ + P+VL++ + RF Q N S ++ND +
Sbjct: 175 YEEVKLEGKDAWRCDKCGRKESSRKRMEVLVHPDVLIVHISRFHPQGWKNTASVEVNDTL 234
Query: 365 QFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTEDGQWFKFNDSV 424
F N Y LL VV GT++ GHY +K G W +ND
Sbjct: 235 LFN------------------NRKYSLLGVVCQNGTLNGGHYFAEAK-RSGTWNVYNDEQ 275
Query: 425 VTSVTEEQVLEQQAYLLFYII 445
VT Y+ FY +
Sbjct: 276 VTK-GSRTYSGSHPYIAFYTL 295
>CE19500 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 900
Score = 69.7 bits (169), Expect = 8e-12
Identities = 54/192 (28%), Positives = 90/192 (46%), Gaps = 12/192 (6%)
Query: 260 THRIFQGYLKNTLQCSQCG-FSKTTIDPIMDLSLEIKNNPK--LEDCLDHFQREETLTDF 316
+H I+ +L+ Q F++ + +++ + + K L++ LD F +E L +
Sbjct: 657 SHDIYSNFLQIVFQWKDLKIFNQYKGNELIEREMTVSTRRKVLLQETLDWFTTKEQLGEQ 716
Query: 317 H-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLH-LNLKP 374
+ C CK+++ KQL L K P +L++ LKRF++ KL V P+ L+L
Sbjct: 717 DSWYCPQCKKHERATKQLALWKLPEILILHLKRFQY-TKWSREKLTWEVVIPVRGLDLTD 775
Query: 375 HLFQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTTVSKTE-DGQWFKFNDSVV--TSVTEE 431
+ E YDL+ V H G++ GHYT + + + +WF FNDS T E
Sbjct: 776 KVANPNHE---KAIYDLIAVSRHYGSLSGGHYTAIGYNDREQKWFDFNDSSANPTYPPAE 832
Query: 432 QVLEQQAYLLFY 443
Y+L Y
Sbjct: 833 PYESSDPYILVY 844
>Hs13994268 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 913
Score = 67.4 bits (163), Expect = 4e-11
Identities = 97/429 (22%), Positives = 177/429 (40%), Gaps = 82/429 (19%)
Query: 11 SNQKLGDAVLKECETVRYLLRHADF-------KNRTMRTMRCMDCGEISCGSTFICLQCG 63
S+ ++ + LKE +V Y AD + + ++ + ++ C S+ I G
Sbjct: 186 SSSEMNEEFLKENNSVEYKKSKADCSRCVSYNREKQLKLKELEENKKLECESSCIMNATG 245
Query: 64 FCGCWNNNHFLDHSQKLGHIFGVNSSNGLVFCFRCGDFMADLVAEIPASQWDTVMEKTEL 123
N +LD +G + + LVF + G S T +K +L
Sbjct: 246 -------NPYLDD---IGLLQALTEKMVLVFLLQQG-----------YSDGYTKWDKLKL 284
Query: 124 PASLHRDGL-QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKH-CNNCDIKSGTKCVSC 181
L + + GL N+G+TC+M++++Q+++ P F +DLL+ + + T C++
Sbjct: 285 FFELFPEKICHGLPNLGNTCYMNAVLQSLLSIPSFADDLLNQSFPWGKIPLNALTMCLAR 344
Query: 182 ALDEIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLH 241
L F+ + + +SA+ I H G++Q DAHE+ L+QL
Sbjct: 345 LL------FFKDTYNIEIKEMLLLNLKKAISAAAEIFH---GNAQNDAHEFLAHCLDQLK 395
Query: 242 TDHARV---------FGSSKAP-------------DCQCITHRIFQGYLKNTLQCSQCG- 278
+ ++ FG P C IT+ F+ L +++ C CG
Sbjct: 396 DNMEKLNTIWKPKSEFGEDNFPKQVFADDPDTSGFSCPVITN--FELELLHSIACKACGQ 453
Query: 279 -FSKTTIDPIMDLSL--EIKNNP-KLEDCLDHFQREETLTDFHYECQSCKQNQGVVKQLT 334
KT ++ + ++L IK +P ++ D F E L Y+C C+ V +
Sbjct: 454 VILKTELNNYLSINLPQRIKAHPSSIQSTFDLFFGAEEL---EYKCAKCEHKTSVGVH-S 509
Query: 335 LHKAPNVLVIQLKRFE------HQLNGQSAKLNDRVQFPLHLN--LKPHLFQIEDEYIPN 386
+ P +L++ LKR+ + N Q ++ ++ H N +P L ED I +
Sbjct: 510 FSRLPRILIVHLKRYSLNEFCALKKNDQEVIISKYLKVSSHCNEGTRPPLPLSEDGEITD 569
Query: 387 IAYDLLNVV 395
+ LL V+
Sbjct: 570 --FQLLKVI 576
>Hs22047537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 248
Score = 66.2 bits (160), Expect = 9e-11
Identities = 49/201 (24%), Positives = 86/201 (42%), Gaps = 26/201 (12%)
Query: 120 KTELPASLHRDGL--QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTK 177
+ +LP S R GL NMG+TC++++ +Q + + P +LS +H C
Sbjct: 65 REKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKC-- 122
Query: 178 CVSCALD-EIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFL 236
C+ C + I + G S ++ GF Q+DAHE+ F
Sbjct: 123 CMLCTMQAHITWPLHSPGHVIQPSQVLAAGFHR--------------GEQEDAHEFLMFT 168
Query: 237 LNQLHT----DHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSL 292
++ + H + SK + H+IF GY ++ + C C T DP +D++L
Sbjct: 169 VDAMKKAFLPGHKHLDNHSKDTT---LIHQIFGGYWRSHINCFHCHGISDTFDPYLDIAL 225
Query: 293 EIKNNPKLEDCLDHFQREETL 313
+I+ ++ L+ + E L
Sbjct: 226 DIQAAQSVKQALEQLVKPEEL 246
>Hs14776897 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 372
Score = 66.2 bits (160), Expect = 9e-11
Identities = 56/198 (28%), Positives = 85/198 (42%), Gaps = 22/198 (11%)
Query: 268 LKNTLQCSQCGFSKTTIDPIMDLSLEI-----KNNPKLEDCLD-HFQREETLTDFHYECQ 321
+K++L C C + ++ L L + K LED L FQ E + C+
Sbjct: 172 VKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCE 231
Query: 322 SCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHL----F 377
+C + + L L P L I L RF + N Q+ K+ + FP L+ L
Sbjct: 232 NCGKKTRGKQVLKLTHLPQTLTIHLMRFSIR-NSQTRKICHSLYFPQSLDFSQILPMKRE 290
Query: 378 QIEDEYIPNIAYDLLNVVSHQGTVDQGHYTT-VSKTEDGQWFKFNDSVVTSVTEEQV--- 433
+ E Y+L V++H G D GHY + DG+WF FNDS + V+ E +
Sbjct: 291 SCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCT 350
Query: 434 -------LEQQAYLLFYI 444
++ AYLL Y+
Sbjct: 351 YGNPNYHWQETAYLLVYM 368
>Hs22047539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 438
Score = 65.1 bits (157), Expect = 2e-10
Identities = 40/116 (34%), Positives = 64/116 (54%), Gaps = 7/116 (6%)
Query: 330 VKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAY 389
+K+ L +L++ KRF + AK VQ+P L+++P++ Q + + Y
Sbjct: 172 MKKACLPGHKQILILVWKRFSDVTGNKIAK---NVQYPECLDMQPYMSQ---QNTGPLVY 225
Query: 390 DLLNVVSHQG-TVDQGHYTTVSKTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFYI 444
L V+ H G + GHY + K ++GQW+K +D+ VT+ VL QQAY+LFYI
Sbjct: 226 VLYAVLVHAGWSCHNGHYFSYVKVQEGQWYKMDDAEVTASGITSVLSQQAYVLFYI 281
>At2g32780 [O] KOG1873 Ubiquitin-specific protease
Length = 1083
Score = 64.7 bits (156), Expect = 3e-10
Identities = 53/211 (25%), Positives = 95/211 (44%), Gaps = 32/211 (15%)
Query: 251 SKAPDCQCITHRIFQGYL--KNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDHFQ 308
+K P+C+ I G++ +NT Q + T P++ I + P ++ ++++
Sbjct: 884 TKLPNCKEEESAIDDGFVGEENT---KQAPITSVTETPLLG-GETISSQPASDNECENWE 939
Query: 309 REETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPL 368
D + + + K++ ++KAP VL I LKRF G+ +KL+ V F
Sbjct: 940 ------DLAVDSEEVIVKRDARKKVLINKAPPVLTIHLKRFSQDARGRVSKLSGHVDFQE 993
Query: 369 HLNLKPHL---FQIEDEYIPNIAYDLLNVVSHQGTVDQGHYTT-------------VSKT 412
++L ++ EDE + Y L +V H G + +GHY + +
Sbjct: 994 FIDLSKYMDTRCSEEDEPV----YRLAGLVEHLGAMSRGHYVSYIRGGHKERRDSDTKEP 1049
Query: 413 EDGQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
W+ +DS V + E+VL +AY+LFY
Sbjct: 1050 NSSIWYHASDSQVRPASLEEVLRSEAYILFY 1080
Score = 60.8 bits (146), Expect = 4e-09
Identities = 71/304 (23%), Positives = 126/304 (41%), Gaps = 63/304 (20%)
Query: 57 FICLQCGFCGCWN-------NNHFLDHSQKLGHIFGVNSSNG-LVFCFRCGDFMA----- 103
++CL+CG+ C + +H + H++ H + N L +CF C +
Sbjct: 93 WLCLECGYYVCGDVGLPTEAQSHVMGHNRLTRHRLVIQCKNPQLRWCFSCQSLLPFDNEE 152
Query: 104 -----DLVAEI--------PASQWDTVMEKTELPASLH-----RDG--LQGLVNMGSTCF 143
DL+ E+ P + + + S++ RDG ++GLVN+G+TCF
Sbjct: 153 NGEKKDLLLEVVKLIRERSPNTYSASFETEFSCSGSIYGGIEARDGYAVRGLVNLGNTCF 212
Query: 144 MSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGNGPGTGKSSSV 203
+S++Q ++ E L D+ VS +L E+ + + +SV
Sbjct: 213 FNSVMQNLLSLDQLREHFLKE------DLSVSGPLVS-SLKELFAE-------SNSEASV 258
Query: 204 SKGFVNLLSASWHINHHLV---GSSQQDAHEYWQFLLNQLHTDHARV---FGSSKAPDCQ 257
+ +N + + G Q D+HE + LL+ L + + + G S + D
Sbjct: 259 FRNEINPRDLFFSVCSQAPQFRGYQQHDSHELLRCLLDGLSIEESSLRKKLGVSDSNDSS 318
Query: 258 C-----ITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEI---KNNPKLEDCLDHFQR 309
+ +F G + +T+ C +CG +P MDLSL + K PK + L Q
Sbjct: 319 TYQKPTLIDSVFGGEISSTVSCLECGHFSKVYEPFMDLSLPVPSMKLPPKKQQILS--QA 376
Query: 310 EETL 313
+E L
Sbjct: 377 KEVL 380
>Hs14777500 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 284
Score = 64.3 bits (155), Expect = 3e-10
Identities = 51/177 (28%), Positives = 79/177 (43%), Gaps = 12/177 (6%)
Query: 268 LKNTLQCSQCGFSKTTIDPIMDLSL---EIKNNP--KLEDCLD-HFQREETLTDFHYECQ 321
+K++L C C + ++ L L ++ + P LED L FQ E + C+
Sbjct: 98 MKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCE 157
Query: 322 SCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHL----F 377
+C + + L L P L I L RF + N Q+ K+ + FP L+ L
Sbjct: 158 NCGKKTRGKQVLKLTHLPQTLTIHLMRFSIR-NSQTRKICHSLYFPQSLDFSQILPMKRE 216
Query: 378 QIEDEYIPNIAYDLLNVVSHQGTVDQGHYTT-VSKTEDGQWFKFNDSVVTSVTEEQV 433
+ E Y+L V++H G D GHY + DG+WF FNDS + V+ E +
Sbjct: 217 SCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDI 273
>Hs8394519 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 372
Score = 63.2 bits (152), Expect = 8e-10
Identities = 55/198 (27%), Positives = 84/198 (41%), Gaps = 22/198 (11%)
Query: 268 LKNTLQCSQCGFSKTTIDPIMDLSLEI-----KNNPKLEDCLD-HFQREETLTDFHYECQ 321
+K++L C C + ++ L L + K LED L FQ E + C+
Sbjct: 172 VKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCE 231
Query: 322 SCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHL----F 377
+C + + L L P L I L RF + N Q+ K+ + FP L+ L
Sbjct: 232 NCGKKTRGKQVLKLTHLPQTLTIHLMRFSIR-NSQTRKICHSLYFPQSLDFSQILPMKRE 290
Query: 378 QIEDEYIPNIAYDLLNVVSHQGTVDQGHYTT-VSKTEDGQWFKFNDSVVTSVTEEQV--- 433
+ E Y+L V++H G D GHY + DG+W FNDS + V+ E +
Sbjct: 291 SCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWSCFNDSNICLVSWEDIQCT 350
Query: 434 -------LEQQAYLLFYI 444
++ AYLL Y+
Sbjct: 351 YGNPNYHWQETAYLLVYM 368
>Hs22056581 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 493
Score = 61.6 bits (148), Expect = 2e-09
Identities = 44/119 (36%), Positives = 66/119 (54%), Gaps = 9/119 (7%)
Query: 328 GVVKQLTLHKAPNVLVIQLKRFEHQLNGQ-SAKLNDRVQFPL-HLNLKPHLFQIEDEYIP 385
G++K+ + K P VL++ LK F + NG+ KL V FPL +L L ++ ++ +
Sbjct: 376 GILKK-EIWKLPPVLLVHLKHFSY--NGRWKQKLQTSVDFPLENLALSQYVIGPKNN-LK 431
Query: 386 NIAYDLLNVVSHQGTVDQGHYTTVSKTEDGQ-WFKFNDSVVTSVTEEQVLEQQAYLLFY 443
N Y+L +V H G +D GHYT K Q WFKF+D V+ ++ V AY+LFY
Sbjct: 432 N--YNLFSVSDHCGGLDGGHYTAYCKNAAKQRWFKFDDHEVSDISVSSVKSSAAYILFY 488
>CE27053 [O] KOG1864 Ubiquitin-specific protease
Length = 515
Score = 61.6 bits (148), Expect = 2e-09
Identities = 82/372 (22%), Positives = 144/372 (38%), Gaps = 69/372 (18%)
Query: 135 LVNMGSTCFMSSIIQTIIHNPYFV---EDL--LSHKHCNNCDIKSGTKCVSCALDEIACD 189
LVN G++CF++S +Q + F E L L K+ + D ++ V C + D
Sbjct: 147 LVNTGNSCFLNSTMQALSSCHSFALRCEQLYCLVRKNIDYFDNEASHSEVLCRKYRVLID 206
Query: 190 FYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVG--------SSQQDAHEYWQFLLNQLH 241
F K S+ SK ++ A+ L+G +QQDAHE+ L +
Sbjct: 207 FLKIMAALTKRSNSSKTQPEIIEANLQTFRELIGMIRNDFANKNQQDAHEFLLMLFEAI- 265
Query: 242 TDHARVFGSSKAPDC----QCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNN 297
D A ++ D Q F+ ++ C C + +D DL++ +++N
Sbjct: 266 DDVAEYKADNEGDDVKEAKQLNPIEAFKFNVETCYVCKGCSKEEVRVDVRNDLAVHMRDN 325
Query: 298 PKLEDCLDHFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNG-- 355
+++ L T T +C SC ++ + + + P LVI L+R+ QL G
Sbjct: 326 LSVQELLS--SSFSTWTPIEKKCSSCNHQHAILSE-RITRFPECLVINLERY--QLEGPQ 380
Query: 356 -QSAKLNDRVQFPLHLNL----------KPHLFQIEDEY--------------------- 383
+ K+N ++ L++ K L Q E +
Sbjct: 381 FSTKKINCSLEPSFELDISSLQKFPEIEKNGLEQSEKQQDSQYGQLLDRMKSCEIIKCCE 440
Query: 384 IPNI-------AYDLLNVVSHQG-TVDQGHYTTVSKTE-DGQWFKFNDSVVTSVTEEQV- 433
NI Y L+ + H G T GHY ++ + + W +D ++ T ++
Sbjct: 441 TKNIIMEEKHDKYSLVAAICHLGETPTNGHYIAYTREDTENSWLYCSDDLIRPATRSEIS 500
Query: 434 --LEQQAYLLFY 443
+ Y+LFY
Sbjct: 501 LSIRTSGYILFY 512
>YBR058c [O] KOG0944 Ubiquitin-specific protease UBP14
Length = 803
Score = 61.2 bits (147), Expect = 3e-09
Identities = 96/422 (22%), Positives = 166/422 (38%), Gaps = 102/422 (24%)
Query: 3 CPHMNQVVSNQKLGDAV-LKECETVRYLLRHADFKNRTMRTMRCMDCGEISCGSTFICLQ 61
CPH K + V L +C + + T C+ CG I CG I
Sbjct: 193 CPHTENFQIPSKPENTVNLNQCSSC----------DLTQNLWLCLHCGNIGCGREQI--- 239
Query: 62 CGFCGCWNNNHFLDHSQ---------KLGHIFGVNSSNGLVFCFRCGDF----------- 101
G ++H LDH + KLG + +SS ++C+ C D
Sbjct: 240 ----GIDGHSHALDHYRSNNNHPLAIKLGSL---SSSTYDLYCYACDDETRFPDNVNLGS 292
Query: 102 ------------MAD--LVAEIPASQ---WDTVM------EKTELPASLHRDGLQGLVNM 138
+AD + ++ Q W M E +L AS + GL+N+
Sbjct: 293 ALQIYGINIQEKIADEKTLVQLQVEQNENWQFRMVDSSGKEFEKLSASKNYGC--GLINL 350
Query: 139 GSTCFMSSIIQTIIHN--PYFVEDLLSHKHCNNCDIKSGTKCVSCA----LDEIACD--F 190
G++C+++S+IQ++++ P + D L K D+ + C L+ + C+
Sbjct: 351 GNSCYLNSVIQSLVNGGVPNWSLDFLGSKF--PLDVVYPDNNLKCQWIKLLNAMKCEPEL 408
Query: 191 YGNG--PGTGKSSSVSKGFVNLLSASWHINHHLVGSS-QQDAHEYWQFLLNQLHTDHARV 247
Y NG P T K NH S+ QQDA E+ FLL+ L +
Sbjct: 409 YPNGIKPTTFKKCIGQ-------------NHQEFSSNRQQDAMEFLTFLLDLLDK---KF 452
Query: 248 FGSSKA--PDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLD 305
F SS + P+ + + + +++ LQC+ CG K + +P + + ++ N + +D L+
Sbjct: 453 FSSSSSGIPN----PNDLVRFMMEDRLQCNICGKVKYSYEPTEAIQIPLEENDEPQDMLE 508
Query: 306 HFQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQ 365
+ ++C +CK+ K+ P L++ R Q N K ++ +
Sbjct: 509 RIKAYFEGQTIEFKCANCKEKVTANKKPGFKSLPQTLILNPIRIRLQ-NWIPVKTSNELS 567
Query: 366 FP 367
P
Sbjct: 568 LP 569
>CE13299 [O] KOG4598 Putative ubiquitin-specific protease
Length = 1292
Score = 60.8 bits (146), Expect = 4e-09
Identities = 39/133 (29%), Positives = 67/133 (50%), Gaps = 8/133 (6%)
Query: 252 KAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKN------NPKLEDCLD 305
K + + + +++G +++ + C +CG D +DL L +K +E+ L
Sbjct: 162 KGTEHEKLIQDLYRGTMEDFVACLKCGRESVKTDYFLDLPLAVKPFGAIHAYKSVEEALT 221
Query: 306 HFQREETLTDFH-YECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNG-QSAKLNDR 363
F + E L + Y C++CK Q K L + + P +L IQLKRF+ N KLND+
Sbjct: 222 AFVQPELLDGSNQYMCENCKSKQDAHKGLRITQFPYLLTIQLKRFDFDYNTMHRIKLNDK 281
Query: 364 VQFPLHLNLKPHL 376
+ FP L+L ++
Sbjct: 282 MTFPDVLDLNDYV 294
>CE09811 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1230
Score = 60.5 bits (145), Expect = 5e-09
Identities = 75/289 (25%), Positives = 114/289 (38%), Gaps = 33/289 (11%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNC----DIKSGTKCVSCALDEIACD 189
GL+N G+ C+++S +Q + P F + + + N + + AL +I
Sbjct: 109 GLINGGNFCYVNSFLQVWFNVPEFRQLIYDFRPSENFVPPEAPRMNVQATMLALQDI--- 165
Query: 190 FYGNGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHT---DHAR 246
FY + + LL + S QQD+ E+ N L DH
Sbjct: 166 FYTLQTTPFNETDKTSNLGKLLR---------LNSEQQDSQEFGLKFFNALERCLPDHPN 216
Query: 247 VFGSSKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPKLEDCLDH 306
+ K +F G + C +CG + + L+L I+ L D LD
Sbjct: 217 GKETLKR------LKDLFTGETCTRIVC-KCGQRSEREETAISLTLNIEGYCTLLDALDA 269
Query: 307 FQREETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQF 366
+ EE L DF +C C + V KQ K P V+VIQL R+++ G+ KL + +
Sbjct: 270 YFGEEHLDDF--KCSKCNKTGDVSKQSDYVKLPPVIVIQLNRYKYTSKGRQ-KLKTPMAY 326
Query: 367 PLHLNLKPHLFQIEDEYIPNIA--YDLLNVVSHQGTVDQGHYTTVSKTE 413
P + K FQ + IP A YDL V T +KTE
Sbjct: 327 PREIPAK--AFQRTNNSIPPPAEMYDLFATVEAIPKPPGTEKPTTAKTE 373
>ECU06g0910 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 726
Score = 56.6 bits (135), Expect = 7e-08
Identities = 40/149 (26%), Positives = 70/149 (46%), Gaps = 21/149 (14%)
Query: 298 PKLEDCLDHFQREETL-TDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQ 356
P L+ C++ F +E L C+ C K++ L P L+IQLKRF++ +N
Sbjct: 590 PTLQHCVNRFLEKEDLHPSERLHCEGCNGKMMFSKKMDLEDLPMYLIIQLKRFQY-VNSS 648
Query: 357 SAKLNDRVQFPLHLNLKPHLFQIEDEYIPN-IAYDLLNVVSH--QGTVDQGHYTTVSKTE 413
K++ +++PL D+++ N + Y ++ V +H GHY VS
Sbjct: 649 PMKISTLIEYPL------------DKFLLNGVEYMVIGVCNHDSDAVTSSGHY--VSYLR 694
Query: 414 DGQWFKFNDSVVTSVTEEQVLEQQAYLLF 442
W+ ND + V ++V ++ Y+LF
Sbjct: 695 KNGWYLCNDQKIERV--DEVDKEHTYVLF 721
>At3g21280 [O] KOG1872 Ubiquitin-specific protease
Length = 488
Score = 56.2 bits (134), Expect = 9e-08
Identities = 57/244 (23%), Positives = 102/244 (41%), Gaps = 19/244 (7%)
Query: 134 GLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYGN 193
GLVN+G+TC+M+S +Q +I P +L +++ D+ + ++ A E+ + +
Sbjct: 105 GLVNLGNTCYMNSTMQCLISVPELKSELSNYQSARTKDVDQTSHMLTVATRELFSELDKS 164
Query: 194 GPGTGKS---SSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGS 250
+ K + A H +H+ QQDA E W +L L + ++
Sbjct: 165 VKAVAPMPFWMVLQKKYPQF--AQLHNGNHM----QQDAEECWTQMLYTL-SQSLKLPSP 217
Query: 251 SKAPDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPK-LEDCLDHFQR 309
S+ PD +F L N L C + + + + L I + L + L H +
Sbjct: 218 SEDPDA---VKALFGLNLLNRLHCQESSEESSETESVFSLKCHISHEVNHLHEGLKHGLK 274
Query: 310 EETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKR-FEHQLNGQSAKLNDRVQFPL 368
E S + VK+ + P L +Q R F + + Q AK+ +V +PL
Sbjct: 275 GE----LEKTSPSLGRTAVYVKESLIDSLPRYLTVQFVRFFWKRESNQKAKILRKVDYPL 330
Query: 369 HLNL 372
L++
Sbjct: 331 ELDI 334
>Hs20483065 [O] KOG1864 Ubiquitin-specific protease
Length = 749
Score = 53.5 bits (127), Expect = 6e-07
Identities = 50/168 (29%), Positives = 73/168 (42%), Gaps = 33/168 (19%)
Query: 302 DCLDHFQREETLT-DFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNG-QSAK 359
D +++F E LT + Y C+SC Q K + L + P L++ L RF L + K
Sbjct: 494 DLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDLRTMRRRK 553
Query: 360 LNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHY------------ 406
+ D V PL L L + + AYDL +VV H G + + GHY
Sbjct: 554 ILDDVSIPLLLRLPLAGGRGQ-------AYDLCSVVVHSGVSSESGHYYCYAREGAARPA 606
Query: 407 ----TTVSKTEDGQWFKFNDSVVTSVTEEQVL-------EQQAYLLFY 443
T + QW+ FND+ V+ + E V + AY+LFY
Sbjct: 607 ASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFY 654
>7293731 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1351
Score = 53.5 bits (127), Expect = 6e-07
Identities = 54/199 (27%), Positives = 84/199 (42%), Gaps = 42/199 (21%)
Query: 126 SLHRDGLQGLVNMGSTCFMSSIIQTIIHN----PYFVEDLLSHKHCNNCDIKSGTK-CVS 180
S+H G GL N+G+TCFM++ +Q + + YF ++ H+ N K GTK ++
Sbjct: 713 SVHAPGATGLHNLGNTCFMNAALQVLFNTQPLAQYFQREM--HRFEVNAANKLGTKGQLA 770
Query: 181 CALDEIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHH---LVGSSQQDAHEYWQFLL 237
E+ + + T + SV+ L + +N + G Q D+ E ++LL
Sbjct: 771 MRYAELLKEVW-----TATTRSVAP-----LKLRFCVNKYAPQFAGGGQHDSQELLEWLL 820
Query: 238 NQLHTDHARVF--------GSSKAPD--------------CQCITHRIFQGYLKNTLQCS 275
+ LH D RV S+ PD Q I +F G LK+ + C
Sbjct: 821 DALHEDLNRVMEKPYSELKDSNGRPDKIVAAEAWSQHHARNQSIIIDLFYGQLKSKVSCL 880
Query: 276 QCGFSKTTIDPIMDLSLEI 294
CG DP LSL +
Sbjct: 881 GCGHESVRFDPFSLLSLPL 899
>YER151c [O] KOG1871 Ubiquitin-specific protease
Length = 912
Score = 52.8 bits (125), Expect = 1e-06
Identities = 55/221 (24%), Positives = 95/221 (42%), Gaps = 50/221 (22%)
Query: 262 RIFQGYLKNTLQCSQCGFSKT-TIDPIMDLSLEIKNNPKLEDCLDHFQREETLTDFHYEC 320
++F G ++ L S++ T+DP + L+I ++ + D F++ YE
Sbjct: 699 KLFGGQFRSVLDIPNNKESQSITLDPFQTIQLDI-SDAGVNDLETAFKKFS-----EYEL 752
Query: 321 QSCKQNQG----VVKQLTLHKAPNVLVIQLKRFE--------------HQLNGQSAKLND 362
K + G KQ + K P VL+IQ KRF + NG+ K+
Sbjct: 753 LPFKSSSGNDVEAKKQTFIDKLPQVLLIQFKRFSFINNVNKDNAMTNYNAYNGRIEKIRK 812
Query: 363 RVQFPLHL----------NLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTT-VS 410
++++ L LK + I+D Y L V+ H G + D GHYT V
Sbjct: 813 KIKYGHELIIPEESMSSITLKNNTSGIDDR-----RYKLTGVIYHHGVSSDGGHYTADVY 867
Query: 411 KTEDGQWFKFNDSVVTSVTEEQVLE--------QQAYLLFY 443
+E +W++ +D +T + ++ VL+ + AY+L Y
Sbjct: 868 HSEHNKWYRIDDVNITELEDDDVLKGGEEASDSRTAYILMY 908
>Hs14211903 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1274
Score = 52.0 bits (123), Expect = 2e-06
Identities = 54/196 (27%), Positives = 77/196 (38%), Gaps = 46/196 (23%)
Query: 131 GLQGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKH------CNNCDIKSG-TKCVSCAL 183
G GL N+G+TCFM+S IQ + + + +S +H N +K KC +
Sbjct: 402 GATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLV 461
Query: 184 DEIACDFYGNGPGTGKSSSVSKGFVNLLSASWHINHH---LVGSSQQDAHEYWQFLLNQL 240
E+ GT K+ V L W I + G QQD+ E FLL+ L
Sbjct: 462 QEL-------WSGTQKN-------VAPLKLRWTIAKYAPRFNGFQQQDSQELLAFLLDGL 507
Query: 241 HTDHARVF--------GSSKAPDCQ--------------CITHRIFQGYLKNTLQCSQCG 278
H D RV S PD + I +F+G L++ ++C CG
Sbjct: 508 HEDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSIVVDLFRGQLRSQVKCKTCG 567
Query: 279 FSKTTIDPIMDLSLEI 294
DP LSL +
Sbjct: 568 HISVRFDPFNFLSLPL 583
>YIL156w [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 1071
Score = 51.2 bits (121), Expect = 3e-06
Identities = 38/128 (29%), Positives = 60/128 (46%), Gaps = 24/128 (18%)
Query: 330 VKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAY 389
VK + P +LVI L RF + L + K N V +PL LN+ + + D + Y
Sbjct: 949 VKTINFVTLPKILVIHLSRFYYDL---TKKNNTVVTYPLILNI---ILKNND----TMKY 998
Query: 390 DLLNVVSHQGTVDQGHYTTVSKTE--------DGQWFKFNDSVVTSVTEE------QVLE 435
L VV+H GT+ GHYT++ + +W+ F+D VV + + ++
Sbjct: 999 KLFGVVNHTGTLISGHYTSLVNKDLEHNVNIGRSKWYYFDDEVVKADRKHGSDKNLKISS 1058
Query: 436 QQAYLLFY 443
Y+LFY
Sbjct: 1059 SDVYVLFY 1066
>CE15678 [O] KOG1867 Ubiquitin-specific protease
Length = 1181
Score = 51.2 bits (121), Expect = 3e-06
Identities = 60/298 (20%), Positives = 120/298 (40%), Gaps = 41/298 (13%)
Query: 133 QGLVNMGSTCFMSSIIQTIIHNPYFVEDLLSHKHCNNCDIKSGTKCVSCALDEIACDFYG 192
+ +VN + C+ S++Q ++ P + SH H +S +C C L + +
Sbjct: 869 RAIVNRNTLCYAISMVQLLMRVPQVYSIVRSHSHKKQKANRS--ECFLCMLTNLISE--- 923
Query: 193 NGPGTGKSSSVSKGFVNLLSASWHINHHLVGSSQQDAHEYWQFLLNQLHTDHARVFGSSK 252
+ + FV LL ++W ++ Q E Q+ N+ ++ +
Sbjct: 924 -----RPRADDTPAFVALLKSNW---KNIEDEGMQCVMEAMQYFFNKFDEEYMH----AH 971
Query: 253 APDCQCITHRIFQGYLKNTLQCSQCGFSKTTIDPIMDLSLEIKNNPK--LEDCLDHFQRE 310
P +F Y +C C D + +S+++ + K ++ +D
Sbjct: 972 PPIRSYFEIEMFIAY-----ECKSCKHVSNAPDKAIYVSIDLSSKTKGTMQSMVDKMANP 1026
Query: 311 ETLTDFHYECQSCKQNQGVVKQLTLHKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHL 370
+ + C+SC Q + + K P VL+ + R + Q G+ + L
Sbjct: 1027 IPVVGMN--CKSCGQ-ETLCSTTRFTKLPEVLLYFVPRVKDQQRGKDMTV---------L 1074
Query: 371 NLKPHLFQIEDEYIPNIAYDLLNVVSHQG-TVDQGHYTT--VSKTEDGQWFKFNDSVV 425
N++ L +D N Y+L + ++H G D GHY + V +T + Q+ +++D+ V
Sbjct: 1075 NVQRQLILKDDNNAHN--YELCSFIAHCGKNGDNGHYKSFEVDRTNEFQYNEYDDAKV 1130
>Hs14249724 [O] KOG1873 Ubiquitin-specific protease
Length = 289
Score = 50.1 bits (118), Expect = 7e-06
Identities = 40/194 (20%), Positives = 82/194 (41%), Gaps = 41/194 (21%)
Query: 1 MVCPHMNQVVSNQKLGDAVLKECETVRYLLRHADFKNRTMRTMRCMDCGEISCGSTFICL 60
+ C H++ +S + A+ + +V + + R D + ++CL
Sbjct: 36 LTCQHVSHAISVNHVKRAIAENLWSVC---------SECLEERRFYDGQLVLTSDIWLCL 86
Query: 61 QCGFCGCWNNN---HFLDH---SQKLGHIFGVNSSNGLVFCFRCG--------------- 99
+CGF GC N+ H L H S+ H +N S +++C+ C
Sbjct: 87 KCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECDEKLSTHCNKKVLAQI 146
Query: 100 -DFMADLVAEIPASQWDTVMEKTELPAS---LHRDG------LQGLVNMGSTCFMSSIIQ 149
DF+ ++ S + +M+ E + + G ++G+ N+G+TCF ++++Q
Sbjct: 147 VDFLQKHASKTQTSAFSRIMKLCEEKCETDEIQKGGKCRNLSVRGITNLGNTCFFNAVMQ 206
Query: 150 TIIHNPYFVEDLLS 163
+ Y + DL++
Sbjct: 207 NLAQT-YTLTDLMN 219
>CE13964 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 376
Score = 49.7 bits (117), Expect = 9e-06
Identities = 55/231 (23%), Positives = 97/231 (41%), Gaps = 30/231 (12%)
Query: 226 QQDAHEYWQFLLNQLHT----DHARVFGSSKAPDCQCITHRIFQGYLKNTLQCSQCG--- 278
Q+DAH+ +L +L + R+ G A D +F ++N +QC C
Sbjct: 147 QEDAHDALLAILGKLDKISVQSNPRLKGRKVADD-------LFGYSIRNEVQCPGCKNKH 199
Query: 279 --FSKTTIDPIMDLSLEIKNNP-KLEDCLDHFQREETLTDFHYECQSCKQNQGVVKQLTL 335
+ T+ + L + +++ + E + F Y C CK+ + TL
Sbjct: 200 VYYEHNTVMTVRMLRKDPSGKSHSIKELMQALFTESKI--FGYNCSKCKKKSDAPVKPTL 257
Query: 336 HKAPNVLVIQLKRFEHQLNGQSAKLNDRVQFPLHLNLKPHLFQIEDEYIPNIAYDLLNVV 395
+AP +L++ + RF G+ ++ P+ LN + + + Y L V
Sbjct: 258 LRAPQILLMHISRFSFDGWGK------KISRPVTLNETLDVTSMATAGASTV-YKLCGAV 310
Query: 396 SHQG-TVDQGHYTTV--SKTEDGQWFKFNDSVVTSVTEEQVLEQQAYLLFY 443
H G T+D GHY V S+ + Q+ NDS V+ T + Q+Y++ Y
Sbjct: 311 IHGGTTLDYGHYWCVARSRKREEQFVTLNDSSVSQHTNPRD-ALQSYIVLY 360
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.137 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,012,174
Number of Sequences: 60738
Number of extensions: 1331945
Number of successful extensions: 4457
Number of sequences better than 1.0e-05: 135
Number of HSP's better than 0.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 112
Number of HSP's that attempted gapping in prelim test: 3898
Number of HSP's gapped (non-prelim): 287
length of query: 446
length of database: 30,389,216
effective HSP length: 110
effective length of query: 336
effective length of database: 23,708,036
effective search space: 7965900096
effective search space used: 7965900096
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)