ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1721 good I KOG4519 Lipid transport and metabolism Phosphomevalonate kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1721 612979 611645 -445
(445 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR220w [I] KOG4519 Phosphomevalonate kinase 382 e-106
SPAC343.01c [I] KOG4519 Phosphomevalonate kinase 186 5e-47
At1g31910 [I] KOG4519 Phosphomevalonate kinase 157 4e-38
>YMR220w [I] KOG4519 Phosphomevalonate kinase
Length = 451
Score = 382 bits (981), Expect = e-106
Identities = 211/447 (47%), Positives = 274/447 (61%), Gaps = 8/447 (1%)
Query: 1 MRSFSAPGKALLAGGYLVLKPEYGSYVVALSSRMHAVVKQDELIGPXXXXXITVKVRSTQ 60
+R+FSAPGKALLAGGYLVL +Y ++VV LS+RMHAV + V+V+S Q
Sbjct: 4 LRAFSAPGKALLAGGYLVLDTKYEAFVVGLSARMHAVAHPYGSL--QGSDKFEVRVKSKQ 61
Query: 61 FNDDEWQYKMDSSSNYSPQELQENKNPFIEKVLSTVFNYFQPDLKLQGN---IVIDIYSD 117
F D EW Y + S + P + +KNPFIEKV++ VF+YF+P++ N VIDI+SD
Sbjct: 62 FKDGEWLYHISPKSGFIPVSIGGSKNPFIEKVIANVFSYFKPNMDDYCNRNLFVIDIFSD 121
Query: 118 AGYHSQAGTKLRSNGVKSFLFHSKSITEVPKTGLGSSAGXXXXXXXXXXSCFKQNLDVSS 177
YHSQ + G + FHS I EVPKTGLGSSAG S F +L+ +
Sbjct: 122 DAYHSQEDSVTEHRGNRRLSFHSHRIEEVPKTGLGSSAGLVTVLTTALASFFVSDLENNV 181
Query: 178 KDDMRLIHNLSQVAHCQAQGKIGSGFDVAAAVYGTITYNRFDPVLIEQLPSPLSSAYHFA 237
+IHNL+QVAHCQAQGKIGSGFDVAAA YG+I Y RF P LI LP S+ Y
Sbjct: 182 DKYREVIHNLAQVAHCQAQGKIGSGFDVAAAAYGSIRYRRFPPALISNLPDIGSATYGSK 241
Query: 238 LVSLIDETDWKIKASRVSLPPRLRLIMGDVNNGSETTKLVAKVNEWYNGNGQAAFKIYKA 297
L L+DE DW I LP L L MGD+ NGSET KLV KV WY+ + + KIY
Sbjct: 242 LAHLVDEEDWNITIKSNHLPSGLTLWMGDIKNGSETVKLVQKVKNWYDSHMPESLKIYTE 301
Query: 298 IDQANTEFVESLRELTALCDQSTSEYEALIETI--NDKGRKTHPLLQKIVHSVHTIREHF 355
+D AN+ F++ L +L L + + + E++ ND + +P + ++ +V TIR F
Sbjct: 302 LDHANSRFMDGLSKLDRLHETHDDYSDQIFESLERNDCTCQKYPEITEVRDAVATIRRSF 361
Query: 356 RLITEQSGADIEPEVQTHLLNAAISLPGVLTGVVPGAGGYDAICLITTDSCNIANETKND 415
R IT++SGADIEP VQT LL+ +L GVLT ++PGAGGYDAI +IT ++ +T ND
Sbjct: 362 RKITKESGADIEPPVQTSLLDDCQTLKGVLTCLIPGAGGYDAIAVITKQDVDLRAQTAND 421
Query: 416 PTFRNVTWLDLNQQDLGIIEEK-PSTY 441
F V WLD+ Q D G+ +EK P TY
Sbjct: 422 KRFSKVQWLDVTQADWGVRKEKDPETY 448
>SPAC343.01c [I] KOG4519 Phosphomevalonate kinase
Length = 426
Score = 186 bits (473), Expect = 5e-47
Identities = 145/453 (32%), Positives = 212/453 (46%), Gaps = 82/453 (18%)
Query: 5 SAPGKALLAGGYLVLKPEYGSYVVALSSRMHA-VVKQDELIGPXXXXXITVKVRSTQFND 63
SAPGK L+AGGY+VL P+Y V+ L+++ +A D+ G TV+V+S QF +
Sbjct: 6 SAPGKVLIAGGYIVLDPQYSGLVIGLTAKGYASTTTLDDKCG-------TVRVKSPQFIN 58
Query: 64 DEWQYKMDSSSN-------YSPQELQENKNPFIEKVLSTVFNYF-----QPDLKLQGNIV 111
EW Y +D + + Y EL++N NPF++ L V NYF QP ++
Sbjct: 59 AEWLYNIDWTVSPIRVHQIYENCELEKNPNPFVQLALFYVINYFFSTGRQP--LCWQDLQ 116
Query: 112 IDIYSDAGYHSQAGTKLRSNGVKSFLFHSKSITEVPKTGLGSSAGXXXXXXXXXXSCFKQ 171
+ + D Y+ Q K F F + ++ +V KTGLGSSA ++
Sbjct: 117 VTLQVDNAYYHQPQLKPDQTSYPKFNFLNCTLGQVHKTGLGSSAAMITSLIGSLFLSLRR 176
Query: 172 NLDVSSKDDMRL-------IHNLSQVAHCQAQGKIGSGFDVAAAVYGTITYNRFDPVLIE 224
D + +++ +HNL+Q+AHC AQGK+GSGFDV AA +G+ Y RFDP LIE
Sbjct: 177 LTDDTGDKSLKIDDSTKVIVHNLAQIAHCSAQGKVGSGFDVGAATWGSCIYRRFDPKLIE 236
Query: 225 QLPSPLSSAYHFALVSLIDETDWKIKASR-------VSLPPRLRLIMGDVNNGSETTKLV 277
QL P Y + ++ T+ + S+ LP L+MGDV GS T +V
Sbjct: 237 QLLVP----YDEQIKNINFSTELRKIVSKKWSDVVPFQLPATYCLLMGDVAGGSSTPGMV 292
Query: 278 AKVNEWYNGNGQAAFK----IYKAIDQANTEFVESLRELTALCDQSTSEYEALIETINDK 333
KV +W N + + +Y + F+ S E+L + +
Sbjct: 293 KKVQQWQKENPEESKNCFDDLYSRVLSIKNCFLSS---------------ESLDSELQSQ 337
Query: 334 GRKTHPLLQKIVHSVHTIREHFRLITEQSGADIEPEVQTHLLNAAISLPGVLTGVVPGAG 393
R +LQ+ IT ++ DIEP QT++L+ LPGV+ VPGAG
Sbjct: 338 FRSIRRILQR--------------ITVEAKVDIEPLKQTNILDNIEQLPGVIGVGVPGAG 383
Query: 394 GYDA-ICLITTDSCNIANETKNDPTFRNVTWLD 425
G+DA CL + I N K TW D
Sbjct: 384 GFDAQFCLAINHTEIIENVIK--------TWKD 408
>At1g31910 [I] KOG4519 Phosphomevalonate kinase
Length = 505
Score = 157 bits (396), Expect = 4e-38
Identities = 138/452 (30%), Positives = 213/452 (46%), Gaps = 57/452 (12%)
Query: 5 SAPGKALLAGGYLVLKPEYGSYVVALSSRMHAVVKQ-DELIGPXXXXX--ITVKVRSTQF 61
SAPGK L+ GGYLVL+ V++ ++R +A+VK +E + P VK+ S Q
Sbjct: 6 SAPGKVLMTGGYLVLEKPNAGLVLSTNARFYAIVKPINEEVKPESWAWKWTDVKLTSPQL 65
Query: 62 NDDEWQYKMDSSSNYSPQELQ--ENKNPFIEKVLSTVFNYFQ----------PDLKLQG- 108
+ + YK+ S ++ + Q + +++NPF+E + L LQG
Sbjct: 66 SRES-MYKL-SLNHLTLQSVSASDSRNPFVEHAIQYAIAAAHLATEKDKESLHKLLLQGL 123
Query: 109 NIVI----DIYSDAGYHSQAGTKLRSNGV------KSFLFHS------KSITEVPKTGLG 152
+I I D YS AG L + S F++ S EV KTGLG
Sbjct: 124 DITILGSNDFYSYRNQIESAGLPLTPESLGTLAPFASITFNAAESNGANSKPEVAKTGLG 183
Query: 153 SSAGXXXXXXXXXXSCFKQNLDVSSK--------DDMRLIHNLSQVAHCQAQGKIGSGFD 204
SSA + +D+S D+ +IH ++Q +HC AQGK+GSGFD
Sbjct: 184 SSAAMTTAVVAALLH-YLGVVDLSDPCKEGKFGCSDLDVIHMIAQTSHCLAQGKVGSGFD 242
Query: 205 VAAAVYGTITYNRFDPVLIEQLPSPLSSAYHFALVSLIDETDWKIKASRVSLPPRLRLIM 264
V+ AVYG+ Y RF P ++ ++ ++ I + W K + SLPP + L +
Sbjct: 243 VSCAVYGSQRYVRFSPEVLSFAQVAVTGLPLNEVIGTILKGKWDNKRTEFSLPPLMNLFL 302
Query: 265 GDV-NNGSETTKLVAKVNEWYNGNGQAAFKIYKAIDQANTEFVESLRELTALCDQSTSEY 323
G+ + GS T +V V +W + + A + ++ + AN E L +L+ L Y
Sbjct: 303 GEPGSGGSSTPSMVGAVKKWQMSDPEKARENWQNLSDANLELETKLNDLSKLAKDHWDVY 362
Query: 324 EALIET----INDKG--RKTHPLLQKIVHSVHTIRE---HFRLITEQSG----ADIEPEV 370
+I++ ++K T P+ + I+ + RE R++ Q G IEPE
Sbjct: 363 LRVIKSCSVLTSEKWVLHATEPINEAIIKELLEAREAMLRIRILMRQMGEAASVPIEPES 422
Query: 371 QTHLLNAAISLPGVLTGVVPGAGGYDAICLIT 402
QT LL++ +S GVL VPGAGG+DAI IT
Sbjct: 423 QTQLLDSTMSAEGVLLAGVPGAGGFDAIFAIT 454
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.133 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,768,498
Number of Sequences: 60738
Number of extensions: 1046560
Number of successful extensions: 2681
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2666
Number of HSP's gapped (non-prelim): 3
length of query: 445
length of database: 30,389,216
effective HSP length: 110
effective length of query: 335
effective length of database: 23,708,036
effective search space: 7942192060
effective search space used: 7942192060
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)