ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1750 good F KOG1622 Nucleotide transport and metabolism GMP synthase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1750 623739 622168 -524
(524 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR217w [F] KOG1622 GMP synthase 913 0.0
SPAP7G5.02c [F] KOG1622 GMP synthase 720 0.0
At1g63660 [F] KOG1622 GMP synthase 515 e-146
Hs4504035 [F] KOG1622 GMP synthase 293 6e-79
CE18084 [F] KOG1622 GMP synthase 284 3e-76
7298764 [F] KOG1622 GMP synthase 280 4e-75
YKL211c_1 [E] KOG0026 Anthranilate synthase beta chain 58 4e-08
At1g25220 [E] KOG0026 Anthranilate synthase beta chain 53 1e-06
At5g57890 [E] KOG0026 Anthranilate synthase beta chain 52 2e-06
At1g25155 [E] KOG0026 Anthranilate synthase beta chain 52 2e-06
At1g25083 [E] KOG0026 Anthranilate synthase beta chain 52 2e-06
At1g24909 [E] KOG0026 Anthranilate synthase beta chain 52 2e-06
CE03105 [R] KOG0370 Multifunctional pyrimidine synthesis protein... 51 5e-06
At1g24807 [E] KOG0026 Anthranilate synthase beta chain 51 5e-06
SPBC1539.09c_1 [E] KOG0026 Anthranilate synthase beta chain 50 6e-06
>YMR217w [F] KOG1622 GMP synthase
Length = 525
Score = 913 bits (2360), Expect = 0.0
Identities = 449/520 (86%), Positives = 482/520 (92%)
Query: 5 EVSNVFDTILVLDFGSQYSHLITRRLREFNVYAEMLPCTQKIADLHWKPKGVILSGGPYS 64
+VSN+FDTILVLDFGSQYSHLITRRLREFN+YAEMLPCTQKI++L W PKGVILSGGPYS
Sbjct: 6 QVSNMFDTILVLDFGSQYSHLITRRLREFNIYAEMLPCTQKISELGWTPKGVILSGGPYS 65
Query: 65 VYEKDAPHVDKAIFDLGVPILGICYGLQEIAWINNTEVGRGEKREYGPATLRVEDKSCPL 124
VY +DAPHVD AIFDL VPILGICYG+QE+AWIN +VGRG+KREYGPATL+V D S L
Sbjct: 66 VYAEDAPHVDHAIFDLNVPILGICYGMQELAWINGKQVGRGDKREYGPATLKVIDDSNSL 125
Query: 125 FANVDHSTVWMSHHDKVHNLPAGFKITATSENSPFCGIANEDKQIYGIQFHPEVTHSTQG 184
F ++ STVWMSH DK+H LP G+K ATS+NSP+CGI +E K IYGIQFHPEVTHSTQG
Sbjct: 126 FKGMNDSTVWMSHGDKLHGLPTGYKTIATSDNSPYCGIVHETKPIYGIQFHPEVTHSTQG 185
Query: 185 KTLLRNFAVDICKASQSWNMENFIDTEINRIRELVGPDAEVIGAVSGGVDSTVAAKLMDR 244
KTLL+NFAVD+C A Q+W MENFIDTEINRIR+LVGP AEVIGAVSGGVDSTVA+KLM
Sbjct: 186 KTLLKNFAVDLCHAKQNWTMENFIDTEINRIRKLVGPTAEVIGAVSGGVDSTVASKLMTE 245
Query: 245 AIGDRFHAIMVDNGVLRLNEAATVKKTLGEGLGINLTVVDASDEFLDKLKGVTDPEKKRK 304
AIGDRFHAI+VDNGVLRLNEAA VKKTL EGLGINL VVDAS+EFL KLKGVTDPEKKRK
Sbjct: 246 AIGDRFHAILVDNGVLRLNEAANVKKTLVEGLGINLMVVDASEEFLSKLKGVTDPEKKRK 305
Query: 305 IIGNTFIHVFEREAAKIQPKNGKEIEFLLQGTLYPDVIESISFKGPSQTIKTHHNVGGLL 364
IIGNTFIHVFEREA KI+PK+GKEI+FLLQGTLYPDVIESISFKGPSQTIKTHHNVGGLL
Sbjct: 306 IIGNTFIHVFEREAEKIKPKDGKEIQFLLQGTLYPDVIESISFKGPSQTIKTHHNVGGLL 365
Query: 365 ENMKLKLIEPLRELFKDEVRELGELLGISHELVWRHPFPGPGIAIRVLGEVTREQVAIAR 424
ENMKLKLIEPLRELFKDEVR LGELLGI H+LVWRHPFPGPGIAIRVLGEVT+EQV IAR
Sbjct: 366 ENMKLKLIEPLRELFKDEVRHLGELLGIPHDLVWRHPFPGPGIAIRVLGEVTKEQVEIAR 425
Query: 425 KADYIYIEEIRKAGLYNNISQAFACLLPVKSVGVMGDQRTYEQVIALRAIETTDFMTADW 484
KAD IYIEEI+KAGLYN ISQAFACLLPVKSVGVMGDQRTY+QVIALRAIETTDFMTADW
Sbjct: 426 KADNIYIEEIKKAGLYNQISQAFACLLPVKSVGVMGDQRTYDQVIALRAIETTDFMTADW 485
Query: 485 YPFEHSFLKKVASRIVNEVDGVARVTYDITSKPPATVEWE 524
+PFEHSFLKKVASRIVNEVDGVARVTYDITSKPPATVEWE
Sbjct: 486 FPFEHSFLKKVASRIVNEVDGVARVTYDITSKPPATVEWE 525
>SPAP7G5.02c [F] KOG1622 GMP synthase
Length = 539
Score = 720 bits (1858), Expect = 0.0
Identities = 364/526 (69%), Positives = 429/526 (81%), Gaps = 7/526 (1%)
Query: 6 VSNVFDTILVLDFGSQYSHLITRRLREFNVYAEMLPCTQKIADLHWKPKGVILSGGPYSV 65
VS+ FDTIL+LDFGSQYSHLI RRLRE +VYAE+LPCTQKI L +KP GVILSGGPYSV
Sbjct: 14 VSSYFDTILILDFGSQYSHLIARRLREIHVYAELLPCTQKIEALPFKPIGVILSGGPYSV 73
Query: 66 YEKDAPHVDKAIFDLGVPILGICYGLQEIAWINNTEVGRGEKREYGPATLRVEDK-SCPL 124
Y+ APHVD A+F+LGVP+LGICYG+QEIAW+N V G +REYGPAT+ +E + +
Sbjct: 74 YDDIAPHVDPAVFELGVPVLGICYGMQEIAWLNGRCVEPGIEREYGPATVSMEPEIKTEV 133
Query: 125 FANVDHST-----VWMSHHDKVHNLPAGFKITATSENSPFCGIANEDKQIYGIQFHPEVT 179
F + +S VWMSH D++ LP G++ ++NSPF IA+ K I G+QFHPEVT
Sbjct: 134 FKSFFNSMPKEFEVWMSHGDRLSALPNGYETIGRTKNSPFAVIAHVTKPIIGLQFHPEVT 193
Query: 180 HSTQGKTLLRNFAVDICKASQSWNMENFIDTEINRIRELVGPDAEVIGAVSGGVDSTVAA 239
H+ G L++NFA++IC A +W+MENF+D EI RIR+++GP VIGAVSGGVDSTVA+
Sbjct: 194 HTPLGLQLIKNFAIEICHAKPNWSMENFVDKEILRIRKMIGPSDHVIGAVSGGVDSTVAS 253
Query: 240 KLMDRAIGDRFHAIMVDNGVLRLNEAATVKKTLGEGLGINLTVVDASDEFLDKLKGVTDP 299
K++ AIGDRFHAIMVDNG+LRLNEA V++TL + LGI LTVVDAS+EF+ KLKGVTDP
Sbjct: 254 KVLKEAIGDRFHAIMVDNGLLRLNEAEIVRETLNKHLGIQLTVVDASEEFIGKLKGVTDP 313
Query: 300 EKKRKIIGNTFIHVFEREAAKIQPKNGKEIEFLLQGTLYPDVIESISFKGPSQTIKTHHN 359
EKKRKIIGNTFIHVFEREA +I + ++E+LLQGTLYPDVIESISFKGPSQTIKTHHN
Sbjct: 314 EKKRKIIGNTFIHVFEREAERIVKETNGKVEYLLQGTLYPDVIESISFKGPSQTIKTHHN 373
Query: 360 VGGLLENMKLKLIEPLRELFKDEVRELGELLGISHELVWRHPFPGPGIAIRVLGEVTREQ 419
VGGLL++MKLKLIEPLRELFKDEVR LGELLGI H LVWRHPFPGPG+ IR+LGEV Q
Sbjct: 374 VGGLLKDMKLKLIEPLRELFKDEVRALGELLGIEHSLVWRHPFPGPGLGIRILGEVNAAQ 433
Query: 420 VAIARKADYIYIEEIRKAGLYNNISQAFACLLPVKSVGVMGDQRTYEQVIALRAIETTDF 479
+ IARKAD+I+I EIR G Y+ ISQAFA LLPVK+VGVMGD+RT+EQVIALRAI T+DF
Sbjct: 434 LEIARKADHIFITEIRNHGYYDKISQAFAALLPVKAVGVMGDKRTHEQVIALRAITTSDF 493
Query: 480 MTADWYP-FEHSFLKKVASRIVNEVDGVARVTYDITSKPPATVEWE 524
MTADWY F FLK V+SRI NEV GV RV YDI+SKPPATVE E
Sbjct: 494 MTADWYDGFSIKFLKLVSSRICNEVSGVNRVLYDISSKPPATVEME 539
>At1g63660 [F] KOG1622 GMP synthase
Length = 534
Score = 515 bits (1327), Expect = e-146
Identities = 271/527 (51%), Positives = 357/527 (67%), Gaps = 14/527 (2%)
Query: 11 DTILVLDFGSQYSHLITRRLREFNVYAEMLPCTQKIADL-HWKPKGVILSGGPYSVYEKD 69
DT+L+LD+GSQY+HLITRR+R NV++ ++ T + + + P+ VILSGGP+SV+ D
Sbjct: 9 DTVLILDYGSQYTHLITRRIRSLNVFSLVISGTSSLKSITSYNPRVVILSGGPHSVHALD 68
Query: 70 APHVDKAIFDL----GVPILGICYGLQEIAWINNTEVGRGEKREYGPATLRVEDKSCPLF 125
AP + + GV +LGICYGLQ I V GE +EYG + V+ KS +F
Sbjct: 69 APSFPEGFIEWAESNGVSVLGICYGLQLIVQKLGGVVVEGESKEYGKMEIEVKGKS-EIF 127
Query: 126 ANV---DHSTVWMSHHDKVHNLPAGFKITATSENSPFCGIANEDKQIYGIQFHPEVTHST 182
+ + VWMSH D+ LP GF++ A S + + K+IYG+Q+HPEVTHS
Sbjct: 128 GSESGGEKQMVWMSHGDEAVKLPEGFEVVAQSAQGAVAALESRKKKIYGLQYHPEVTHSP 187
Query: 183 QGKTLLRNFAVDICKASQSWNMENFIDTEINRIRELVGPDAEVIGAVSGGVDSTVAAKLM 242
+G LR+F D+C S W ME+ ++ EI I + V D VI A+SGGVDSTVAA L+
Sbjct: 188 KGMETLRHFLFDVCGVSADWKMEDLMEEEIKVINKTVASDEHVICALSGGVDSTVAATLV 247
Query: 243 DRAIGDRFHAIMVDNGVLRLNEAATVKKTLGEGLGINLTVVDASDEFLDKLKGVTDPEKK 302
+AIGDR H I VDNG+LR E V T L + +T VDAS+ FL +LKGV DPE K
Sbjct: 248 HKAIGDRLHCIFVDNGLLRYKEQERVMDTFERDLHLPVTCVDASERFLSELKGVVDPETK 307
Query: 303 RKIIGNTFIHVFEREAAKIQPKNGKEIEFLLQGTLYPDVIESISFKGP----SQTIKTHH 358
RKIIG FI++F++ A +++ K+GK+ FL+QGTLYPDVIES G S TIK+HH
Sbjct: 308 RKIIGREFINIFDQFAQELEKKHGKKPAFLVQGTLYPDVIESCPPPGTDRTHSHTIKSHH 367
Query: 359 NVGGLLENMKLKLIEPLRELFKDEVRELGELLGISHELVWRHPFPGPGIAIRVLGEVTR- 417
NVGGL ++MKLKLIEPL+ LFKDEVRELG +L + + RHPFPGPG+A+RVLG+VT+
Sbjct: 368 NVGGLPKDMKLKLIEPLKLLFKDEVRELGRILNVPVGFLKRHPFPGPGLAVRVLGDVTQG 427
Query: 418 EQVAIARKADYIYIEEIRKAGLYNNISQAFACLLPVKSVGVMGDQRTYEQVIALRAIETT 477
+ + R+ D I+I+ IR AGLY++I QAFA LPV+SVGV GD+RT+ V+ALRA+ +
Sbjct: 428 NALEVLRQVDEIFIQSIRDAGLYDSIWQAFAVFLPVRSVGVQGDKRTHSHVVALRAVTSQ 487
Query: 478 DFMTADWYPFEHSFLKKVASRIVNEVDGVARVTYDITSKPPATVEWE 524
D MTADW+ FEH FL V+ +I N V GV RV DITSKPP+T+EWE
Sbjct: 488 DGMTADWFNFEHKFLDDVSRKICNSVQGVNRVVLDITSKPPSTIEWE 534
>Hs4504035 [F] KOG1622 GMP synthase
Length = 693
Score = 293 bits (749), Expect = 6e-79
Identities = 201/561 (35%), Positives = 296/561 (51%), Gaps = 65/561 (11%)
Query: 13 ILVLDFGSQYSHLITRRLREFNVYAEMLPC-TQKIADLHWKPKGVILSGGPYSVYEKDAP 71
+++LD G+QY +I RR+RE V +E+ P T A + +I+SGGP SVY +DAP
Sbjct: 28 VVILDAGAQYGKVIDRRVRELFVQSEIFPLETPAFAIKEQGFRAIIISGGPNSVYAEDAP 87
Query: 72 HVDKAIFDLGVPILGICYGLQEIAWINNTEVGRGEKREYGPATLRVEDKSCPLFANVD-H 130
D AIF +G P+LGICYG+Q + + V + RE G + V D +C LF +
Sbjct: 88 WFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHKKSVREDGVFNISV-DNTCSLFRGLQKE 146
Query: 131 STVWMSHHDKVHNLPAGFKITATSENSPFCGIANEDKQIYGIQFHPEVTHSTQGKTLLRN 190
V ++H D V + GFK+ A S N GIANE K++YG QFHPEV + GK +L+N
Sbjct: 147 EVVLLTHGDSVDKVADGFKVVARSGNI-VAGIANESKKLYGAQFHPEVGLTENGKVILKN 205
Query: 191 FAVDICKASQSWNMENFIDTEINRIRELVGPDAEVIGAVSGGVDSTVAAKLMDRAIG-DR 249
F DI S ++ ++N I I+E VG ++V+ +SGGVDSTV L++RA+ ++
Sbjct: 206 FLYDIAGCSGTFTVQNRELECIREIKERVG-TSKVLVLLSGGVDSTVCTALLNRALNQEQ 264
Query: 250 FHAIMVDNGVLRLNEAATVKKTLGEGLGINLTVVDASDEFLD------------------ 291
A+ +DNG +R E+ +V++ L + LGI + V++A+ F +
Sbjct: 265 VIAVHIDNGFMRKRESQSVEEAL-KKLGIQVKVINAAHSFYNGTTTLPISDEDRTPRKRI 323
Query: 292 --KLKGVTDPEKKRKIIGNTFIHVFEREAAKIQPKNGKEIEFLLQGTLYPDVIESISF-- 347
L T PE+KRKIIG+TF+ + ++ K E FL QGTL PD+IES S
Sbjct: 324 SKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMNLK--PEEVFLAQGTLRPDLIESASLVA 381
Query: 348 KGPSQTIKTHHNVGGLLENMKL--KLIEPLRELFKDEVRELGELLGISHELVWRHPFPGP 405
G ++ IKTHHN L+ ++ K+IEPL++ KDEVR LG LG+ ELV RHPFPGP
Sbjct: 382 SGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVRILGRELGLPEELVSRHPFPGP 441
Query: 406 GIAIRVL-------------------------GEVTREQVAIARKADYIYIEEIRKAGLY 440
G+AIRV+ V + + R E+ K
Sbjct: 442 GLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPHTLLQRVKACTTEEDQEKLMQI 501
Query: 441 NNISQAFACLLPVKSVGVMGDQRTYEQVIALRAIETTDFMTADWYPFEHSFLKKVASRIV 500
++ A LLP+K+VGV GD R+Y V + + + D+ + FL ++ R+
Sbjct: 502 TSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDWESL-------IFLARLIPRMC 554
Query: 501 NEVDGVARVTYDITSKPPATV 521
+ V+ V + +PP V
Sbjct: 555 HNVNRVVYIFGPPVKEPPTDV 575
Score = 53.1 bits (126), Expect = 1e-06
Identities = 34/114 (29%), Positives = 59/114 (50%), Gaps = 4/114 (3%)
Query: 415 VTREQVAIARKADYIYIEEIRKAGLYNNISQAFACLLPVK-SVGVMGDQRTYEQVIALRA 473
+T ++ R+AD+ +R++G ISQ L P+ + Q + ++ + +R
Sbjct: 580 LTTGVLSTLRQADFEAHNILRESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRT 639
Query: 474 IETTDFMTADWYPFEHSFLKKVASRIVNEVD---GVARVTYDITSKPPATVEWE 524
T+DFMT + +V ++V E+ G++R+ YD+TSKPP T EWE
Sbjct: 640 FITSDFMTGIPATPGNEIPVEVVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE 693
>CE18084 [F] KOG1622 GMP synthase
Length = 792
Score = 284 bits (726), Expect = 3e-76
Identities = 208/579 (35%), Positives = 296/579 (50%), Gaps = 73/579 (12%)
Query: 3 PVEVSNVFDTILVLDFGSQYSHLITRRLREFNVYAEMLPCTQKIADLHWKP--KGVILSG 60
PVE + + I +LDFG+QY +I RR+RE V +EM P L KG+I+SG
Sbjct: 98 PVEKVSSGERIAILDFGAQYGKVIDRRVRELLVQSEMFPLNTTARTLIELGGFKGIIISG 157
Query: 61 GPYSVYEKDAPHVDKAIFDLGVPILGICYGLQEIAWINNTEVGRGEKREYGPATLRVEDK 120
GP SV+E +AP +D IF G+P+LGICYG Q + +N V R RE G ++V D
Sbjct: 158 GPNSVFEPEAPSIDPEIFTCGLPVLGICYGFQLMNKLNGGTVTREHIREDGACEIQV-DT 216
Query: 121 SCPLFANVDHS-TVWMSHHDKVH--NLPAGFKITATSENSPFCGIANEDKQIYGIQFHPE 177
S LF + + TV ++H D V + FK+ A S + GI NE++++YG+QFHPE
Sbjct: 217 SVHLFNGLHKTETVLLTHGDSVSEATVAPDFKVMAKSGHH-VAGICNENRKLYGVQFHPE 275
Query: 178 VTHSTQGKTLLRNFAVDICKASQSWNMENFIDTEINRIRELVGPDAEVIGAVSGGVDSTV 237
V +T G + NF + ++ ++N + I+ I +VG D +V+ VSGGVDS V
Sbjct: 276 VDLTTNGTKMFENFLFKVVGCCGNFTIQNREQSCISEINSIVG-DKKVLVMVSGGVDSAV 334
Query: 238 AAKLMDRAIG-DRFHAIMVDNGVLRLNEAATVKKTLG------EGLGINLTVVDASDEFL 290
A L+ RA+G +R AI +DNG +R E+ V+K+L T +++
Sbjct: 335 CAALLRRALGPNRVTAIHIDNGFMRHEESDAVEKSLAALDLPIHRYNFGTTFRSSTEHCK 394
Query: 291 D---KLKGVTDPEKKRKIIGNTFIHVFEREAAKIQPKNGKEIEFLLQGTLYPDVIESIS- 346
D L DPE KRKIIGNTFI V ++ + FL QGTL PD+IES S
Sbjct: 395 DGEVALDECDDPEMKRKIIGNTFIRV--KDVIMKDLNINHDEYFLAQGTLRPDLIESASA 452
Query: 347 -FKGPSQTIKTHHNVGGLLENMKL--KLIEPLRELFKDEVRELGELLGISHELVWRHPFP 403
G + TIKTHHN L+ ++ K++EPL++ KDEVRELG+ LG+ +V RHPFP
Sbjct: 453 LASGHADTIKTHHNDTFLVRELRKLGKVVEPLKDFHKDEVRELGKDLGLPESIVQRHPFP 512
Query: 404 GPGIAIRVL-----------------GEVTREQVAIARK------------ADYIYIEEI 434
GPG+AIR+L G+V + + + +++ E+
Sbjct: 513 GPGLAIRILCASDKRPELMFNGPMYNGDVQGRIIDVTEQFLNSAINPSQGIYEHLQFEQA 572
Query: 435 RKAGLYN-----------NISQAFACLLPVKSVGVMGDQRTYEQVIALRAIETTDFMTAD 483
R L + Q A +LP+K+VGV GD R+Y +AL + +
Sbjct: 573 RNNVLLSLSERDRQLAEQQTFQISAHILPIKTVGVQGDARSYSYAVAL---------STE 623
Query: 484 WYPFEHSFLKKVASRIVNEVDGVARVTYDITSKPPATVE 522
P L AS I GV RV Y SK ++E
Sbjct: 624 QRPIPWKLLFAYASVIPKLFHGVNRVVYAFGSKIEFSIE 662
>7298764 [F] KOG1622 GMP synthase
Length = 683
Score = 280 bits (716), Expect = 4e-75
Identities = 203/551 (36%), Positives = 297/551 (53%), Gaps = 67/551 (12%)
Query: 11 DTILVLDFGSQYSHLITRRLREFNVYAEMLPCTQKIADLHWKP-KGVILSGGPYSVYEKD 69
D I++LD G+QY +I R++RE V ++LP A + +G+I+SGGP SVY +D
Sbjct: 17 DKIVILDAGAQYGKVIDRKVRELFVETDILPLDTPAATIRNNGYRGIIISGGPNSVYAED 76
Query: 70 APHVDKAIFDLGVPILGICYGLQEIAWINNTEVGRGEKREYGPATLRVEDKSCPLFANVD 129
AP D +F L +P+LGICYG+Q I V + + RE G + +E SCPLF+ +
Sbjct: 77 APSYDPDLFKLKIPMLGICYGMQLINKEFGGTVLKKDVREDGQQNIEIET-SCPLFSRLS 135
Query: 130 HS-TVWMSHHDKVHNLPAGFKITATSENSPFCGIANEDKQIYGIQFHPEVTHSTQGKTLL 188
+ +V ++H D V + KI S N I NE +IYG+QFHPEV + GK +L
Sbjct: 136 RTQSVLLTHGDSVERVGENLKIGGWSTNRIVTAIYNEVLRIYGVQFHPEVDLTINGKQML 195
Query: 189 RNFAVDICKASQSWNMENFIDTEINRIRELVGPDAEVIGAVSGGVDSTVAAKLMDRAI-G 247
NF +IC+ + ++ M + + I IRE VG + +V+ VSGGVDS+V A L+ RA+
Sbjct: 196 SNFLYEICELTPNFTMGSRKEECIRYIREKVG-NNKVLLLVSGGVDSSVCAALLRRALYP 254
Query: 248 DRFHAIMVDNGVLRLNEAATVKKTLGEGLGINLTVVDASDEFLDKLKGVT---------- 297
+ A+ VDNG +R E+ V+++L + +GI+L V F LKG T
Sbjct: 255 HQIIAVHVDNGFMRKKESEKVERSLRD-IGIDLIVRKEGYTF---LKGTTQVKRPGQYSV 310
Query: 298 ----------DPEKKRKIIGNTFIHVFEREAAKIQPKNGKEIEFLLQGTLYPDVIESIS- 346
+PE+KRKIIG+ F+ V A+++ K E L QGTL PD+IES S
Sbjct: 311 VETPMLCQTYNPEEKRKIIGDIFVKVTNDVVAELKLK--PEEVMLAQGTLRPDLIESASS 368
Query: 347 -FKGPSQTIKTHHNVGGLLENMKL--KLIEPLRELFKDEVRELGELLGISHELVWRHPFP 403
++TIKTHHN L+ ++ +++EPL + KDEVR+LG LG+ ELV R PFP
Sbjct: 369 MVSTNAETIKTHHNDTDLIRELRNAGRVVEPLCDFHKDEVRDLGNDLGLPQELVERQPFP 428
Query: 404 GPGIAIRVL--------GEVTREQVAIARKADY--------IYIEEIRKAG--------- 438
GPG+AIRVL + + QV I DY I + A
Sbjct: 429 GPGLAIRVLCAEEAYMEKDYSETQVIIRVIVDYKNKLQKNHALINRVTAATSEAEQKDLM 488
Query: 439 LYNNISQAFACLLPVKSVGVMGDQRTYEQVIALRAIETTDFMTADWYPFEHSFLKKVASR 498
++ SQ A LLP++SVGV GD+R+Y V+ L + ++ + FL K+ R
Sbjct: 489 RISSNSQIQATLLPIRSVGVQGDKRSYSYVVGLSTSQEPNWQ-------DLLFLAKIIPR 541
Query: 499 IVNEVDGVARV 509
I++ V+ V +
Sbjct: 542 ILHNVNRVCYI 552
Score = 61.6 bits (148), Expect = 3e-09
Identities = 42/108 (38%), Positives = 60/108 (54%), Gaps = 9/108 (8%)
Query: 424 RKADYIYIEEIRKAGLYNNISQAFACLLPVK-SVGVMGDQRTYEQVIALRAIETTDFMTA 482
R+AD I E I +AGLY ISQ L+PV + + + + LR T DFMT
Sbjct: 578 RQADDIANEIIMQAGLYRKISQMPVVLIPVHFDRDPINRTPSCRRSVVLRPFITNDFMTG 637
Query: 483 DWYPFEHSFLK---KVASRIVNEV---DGVARVTYDITSKPPATVEWE 524
P E ++ +V ++IV ++ DG++RV YD+T+KPP T EWE
Sbjct: 638 --VPAEPGSVQMPLQVLNQIVRDISKLDGISRVLYDLTAKPPGTTEWE 683
>YKL211c_1 [E] KOG0026 Anthranilate synthase beta chain
Length = 206
Score = 57.8 bits (138), Expect = 4e-08
Identities = 45/167 (26%), Positives = 75/167 (43%), Gaps = 19/167 (11%)
Query: 34 NVYAEMLPCTQKIADLHWKPKGVILSGGPYSVYEKDAPHVDKAI-------FDLGVPILG 86
+VY +IA L+ P +++S GP P D I F +P+ G
Sbjct: 39 SVYRNDAITVPEIAALN--PDTLLISPGP------GHPKTDSGISRDCIRYFTGKIPVFG 90
Query: 87 ICYGLQEIAWINNTEVGRGEKREYGPATLRVEDKSCPLFANVDHSTVWMSHHDKV---HN 143
IC G Q + + EV + +G T + +C +F NV +H +
Sbjct: 91 ICMGQQCMFDVFGGEVAYAGEIVHGK-TSPISHDNCGIFKNVPQGIAVTRYHSLAGTESS 149
Query: 144 LPAGFKITATSENSPFCGIANEDKQIYGIQFHPEVTHSTQGKTLLRN 190
LP+ K+TA++EN G+ ++ + G+QFHPE + +G ++RN
Sbjct: 150 LPSCLKVTASTENGIIMGVRHKKYTVEGVQFHPESILTEEGHLMIRN 196
>At1g25220 [E] KOG0026 Anthranilate synthase beta chain
Length = 276
Score = 52.8 bits (125), Expect = 1e-06
Identities = 52/200 (26%), Positives = 99/200 (49%), Gaps = 14/200 (7%)
Query: 4 VEVSNVFDTILVLDFGSQYSHLITRRLREFNVYAEMLPCTQ-KIADLHWK-PKGVILSGG 61
V S I+V+D +++ + + + E + E+ + + +L K P+GV++S G
Sbjct: 66 VNSSKQHGPIIVIDNYDSFTYNLCQYMGELGCHFEVYRNDELTVEELKKKNPRGVLISPG 125
Query: 62 PYSVYEKDAPHVDKAIFDLG--VPILGICYGLQEIAWINNTEVGRGEKRE-YGPATLRVE 118
P + +D+ + + +LG VP+ G+C GLQ I ++ R +G +++
Sbjct: 126 PGT--PQDSGISLQTVLELGPLVPLFGVCMGLQCIGEAFGGKIVRSPFGVMHGKSSMVHY 183
Query: 119 DKSCP--LFANVDHSTVWMSHHDKV---HNLPAG-FKITATSENSPFCGIANED-KQIYG 171
D+ LF+ + + + +H V P+ ++TA +E+ + K I G
Sbjct: 184 DEKGEEGLFSGLSNPFIVGRYHSLVIEKDTFPSDELEVTAWTEDGLVMAARHRKYKHIQG 243
Query: 172 IQFHPEVTHSTQGKTLLRNF 191
+QFHPE +T+GKT++RNF
Sbjct: 244 VQFHPESIITTEGKTIVRNF 263
>At5g57890 [E] KOG0026 Anthranilate synthase beta chain
Length = 273
Score = 52.4 bits (124), Expect = 2e-06
Identities = 50/198 (25%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Query: 6 VSNVFDTILVLDFGSQYSHLITRRLREFNVYAEMLPCTQKIAD--LHWKPKGVILSGGPY 63
V N I+V+D +++ + + + E + E+ + + KP+G+++S GP
Sbjct: 65 VVNSSGPIIVIDNYDSFTYNLCQYMGELGCHFEVYRNDELTVEELKRKKPRGLLISPGPG 124
Query: 64 SVYEKDAPHVDKAIFDLG--VPILGICYGLQEIAWINNTEVGRGEKRE-YGPATLRVEDK 120
+ +D+ + + +LG VP+ G+C GLQ I ++ R +G +++ D+
Sbjct: 125 T--PQDSGISLQTVLELGPLVPLFGVCMGLQCIGEAFGGKIVRSPFGVMHGKSSMVHYDE 182
Query: 121 SCP--LFANVDHSTVWMSHHDKV---HNLPAG-FKITATSENSPFCGIANED-KQIYGIQ 173
LF+ + + + +H V + P+ ++TA +E+ + K I G+Q
Sbjct: 183 KGEEGLFSGLSNPFLVGRYHSLVIEKDSFPSDELEVTAWTEDGLVMAARHRKYKHIQGVQ 242
Query: 174 FHPEVTHSTQGKTLLRNF 191
FHPE +T+GKT++RNF
Sbjct: 243 FHPESIITTEGKTIVRNF 260
>At1g25155 [E] KOG0026 Anthranilate synthase beta chain
Length = 222
Score = 52.4 bits (124), Expect = 2e-06
Identities = 50/191 (26%), Positives = 97/191 (50%), Gaps = 14/191 (7%)
Query: 13 ILVLDFGSQYSHLITRRLREFNVYAEMLPCTQ-KIADLHWK-PKGVILSGGPYSVYEKDA 70
I+V+D +++ + + + E + E+ + + +L K P+GV++S GP + +D+
Sbjct: 21 IIVIDNYDSFTYNLCQYMGELQCHFEVYRNDELTVEELKRKNPRGVLISPGPGT--PQDS 78
Query: 71 PHVDKAIFDLG--VPILGICYGLQEIAWINNTEVGRGEKRE-YGPATLRVEDKSCP--LF 125
+ + +LG VP+ G+C GLQ I ++ R +G +++ D+ LF
Sbjct: 79 GISLQTVLELGPLVPLFGVCMGLQCIGEAFGGKIVRSPFGVMHGKSSMVHYDEKGEEGLF 138
Query: 126 ANVDHSTVWMSHHDKV---HNLPAG-FKITATSENSPFCGIANED-KQIYGIQFHPEVTH 180
+ + + + +H V P+ ++TA +E+ + K I G+QFHPE
Sbjct: 139 SGLSNPFIVGRYHSLVIEKDTFPSDELEVTAWTEDGLVMAARHRKYKHIQGVQFHPESII 198
Query: 181 STQGKTLLRNF 191
+T+GKT++RNF
Sbjct: 199 TTEGKTIVRNF 209
>At1g25083 [E] KOG0026 Anthranilate synthase beta chain
Length = 222
Score = 52.4 bits (124), Expect = 2e-06
Identities = 50/191 (26%), Positives = 97/191 (50%), Gaps = 14/191 (7%)
Query: 13 ILVLDFGSQYSHLITRRLREFNVYAEMLPCTQ-KIADLHWK-PKGVILSGGPYSVYEKDA 70
I+V+D +++ + + + E + E+ + + +L K P+GV++S GP + +D+
Sbjct: 21 IIVIDNYDSFTYNLCQYMGELQCHFEVYRNDELTVEELKRKNPRGVLISPGPGT--PQDS 78
Query: 71 PHVDKAIFDLG--VPILGICYGLQEIAWINNTEVGRGEKRE-YGPATLRVEDKSCP--LF 125
+ + +LG VP+ G+C GLQ I ++ R +G +++ D+ LF
Sbjct: 79 GISLQTVLELGPLVPLFGVCMGLQCIGEAFGGKIVRSPFGVMHGKSSMVHYDEKGEEGLF 138
Query: 126 ANVDHSTVWMSHHDKV---HNLPAG-FKITATSENSPFCGIANED-KQIYGIQFHPEVTH 180
+ + + + +H V P+ ++TA +E+ + K I G+QFHPE
Sbjct: 139 SGLSNPFIVGRYHSLVIEKDTFPSDELEVTAWTEDGLVMAARHRKYKHIQGVQFHPESII 198
Query: 181 STQGKTLLRNF 191
+T+GKT++RNF
Sbjct: 199 TTEGKTIVRNF 209
>At1g24909 [E] KOG0026 Anthranilate synthase beta chain
Length = 222
Score = 52.4 bits (124), Expect = 2e-06
Identities = 50/191 (26%), Positives = 97/191 (50%), Gaps = 14/191 (7%)
Query: 13 ILVLDFGSQYSHLITRRLREFNVYAEMLPCTQ-KIADLHWK-PKGVILSGGPYSVYEKDA 70
I+V+D +++ + + + E + E+ + + +L K P+GV++S GP + +D+
Sbjct: 21 IIVIDNYDSFTYNLCQYMGELQCHFEVYRNDELTVEELKRKNPRGVLISPGPGT--PQDS 78
Query: 71 PHVDKAIFDLG--VPILGICYGLQEIAWINNTEVGRGEKRE-YGPATLRVEDKSCP--LF 125
+ + +LG VP+ G+C GLQ I ++ R +G +++ D+ LF
Sbjct: 79 GISLQTVLELGPLVPLFGVCMGLQCIGEAFGGKIVRSPFGVMHGKSSMVHYDEKGEEGLF 138
Query: 126 ANVDHSTVWMSHHDKV---HNLPAG-FKITATSENSPFCGIANED-KQIYGIQFHPEVTH 180
+ + + + +H V P+ ++TA +E+ + K I G+QFHPE
Sbjct: 139 SGLSNPFIVGRYHSLVIEKDTFPSDELEVTAWTEDGLVMAARHRKYKHIQGVQFHPESII 198
Query: 181 STQGKTLLRNF 191
+T+GKT++RNF
Sbjct: 199 TTEGKTIVRNF 209
>CE03105 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2198
Score = 50.8 bits (120), Expect = 5e-06
Identities = 65/220 (29%), Positives = 95/220 (42%), Gaps = 19/220 (8%)
Query: 3 PVEVSNVFDTILVLDFGSQYSHLITRRLREFNVYAEMLPCTQKIADLHWKPKGVILSGGP 62
PV + TIL +D G + + + R F V +++P I D G+ LS GP
Sbjct: 171 PVVYGSGDQTILAVDCGLKNNQIRCLAKRGFRV--KVVPWNHPI-DTESDYDGLFLSNGP 227
Query: 63 YSVYEKDAPHVD---KAIFDLGVPILGICYGLQEIAWINNTEVG-RGEKREYGPATLRVE 118
E AP VD K I PI GIC G Q I + +G + K +YG R
Sbjct: 228 GDP-EICAPLVDRLAKVIARGDKPIFGICLGHQ----ILSRAIGAKTYKLKYGN---RGH 279
Query: 119 DKSCPLFANVDHSTVWMSHHDKVH--NLPAGFKITATSENSPFC-GIANEDKQIYGIQFH 175
++ C +A +H V +LPA +K T+EN GI + K + +QFH
Sbjct: 280 NQPCTHYATGRCYITSQNHGYAVDPDSLPADWKALFTNENDKTNEGIVHSSKPFFSVQFH 339
Query: 176 PEVTHSTQGKTLLRNFAVDICKASQSWNMENFIDTEINRI 215
PE T L + D + ++S N +D E+ R+
Sbjct: 340 PEHTAGPTDCEFLFDVFADSVRQAKSGTFMN-VDQELTRL 378
>At1g24807 [E] KOG0026 Anthranilate synthase beta chain
Length = 235
Score = 50.8 bits (120), Expect = 5e-06
Identities = 43/149 (28%), Positives = 77/149 (50%), Gaps = 12/149 (8%)
Query: 53 PKGVILSGGPYSVYEKDAPHVDKAIFDLG--VPILGICYGLQEIAWINNTEVGRGEKRE- 109
P+GV++S GP + +D+ + + +LG VP+ G+C GLQ I ++ R
Sbjct: 76 PRGVLISPGPGT--PQDSGISLQTVLELGPLVPLFGVCMGLQCIGEAFGGKIVRSPFGVM 133
Query: 110 YGPATLRVEDKSCP--LFANVDHSTVWMSHHDKV---HNLPAG-FKITATSENSPFCGIA 163
+G +++ D+ LF+ + + + +H V P+ ++TA +E+
Sbjct: 134 HGKSSMVHYDEKGEEGLFSGLSNPFIVGRYHSLVIEKDTFPSDELEVTAWTEDGLVMAAR 193
Query: 164 NED-KQIYGIQFHPEVTHSTQGKTLLRNF 191
+ K I G+QFHPE +T+GKT++RNF
Sbjct: 194 HRKYKHIQGVQFHPESIITTEGKTIVRNF 222
>SPBC1539.09c_1 [E] KOG0026 Anthranilate synthase beta chain
Length = 238
Score = 50.4 bits (119), Expect = 6e-06
Identities = 39/144 (27%), Positives = 67/144 (46%), Gaps = 7/144 (4%)
Query: 53 PKGVILSGGPYSVYEKDAPHVDKAI--FDLGVPILGICYGLQEIAWINNTEVGRGEKREY 110
P ++LS GP +D ++AI F +PILG+C GLQ I +V + +
Sbjct: 72 PLKLVLSPGPGHP-ARDGGICNEAISRFAGKIPILGVCMGLQCIFETMGGKVDSAGEIIH 130
Query: 111 GPATLRVEDKSCPLFANVDHSTVWMSHHD---KVHNLPAGFKITATSENSPFCGIANEDK 167
G + ++ + + + +H K+ +LP +T+ +EN G ++
Sbjct: 131 GKVS-KINHDGLGFYQGIPQNISVTRYHSLAGKISSLPDCLDVTSWTENGVIMGARHKKY 189
Query: 168 QIYGIQFHPEVTHSTQGKTLLRNF 191
I G+Q+HPE S GK ++NF
Sbjct: 190 AIEGVQYHPESILSEYGKEYIQNF 213
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.138 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,228,945
Number of Sequences: 60738
Number of extensions: 1422617
Number of successful extensions: 3121
Number of sequences better than 1.0e-05: 15
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 3071
Number of HSP's gapped (non-prelim): 20
length of query: 524
length of database: 30,389,216
effective HSP length: 111
effective length of query: 413
effective length of database: 23,647,298
effective search space: 9766334074
effective search space used: 9766334074
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)