ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1799 good R KOG1877 General function prediction only Putative transmembrane protein cmp44E
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1799 637629 639818 730
(730 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR212c [R] KOG1877 Putative transmembrane protein cmp44E 558 e-158
SPCC794.08 [R] KOG1877 Putative transmembrane protein cmp44E 90 1e-17
Hs14741682 [R] KOG1877 Putative transmembrane protein cmp44E 52 2e-06
>YMR212c [R] KOG1877 Putative transmembrane protein cmp44E
Length = 782
Score = 558 bits (1438), Expect = e-158
Identities = 327/781 (41%), Positives = 467/781 (58%), Gaps = 59/781 (7%)
Query: 1 MGFLFTPKHQKLVNQCYPPGRTPDKKPKGSETSYLLYYVNSRRPKLEKVSSYLVKRSTTD 60
M +FTPKHQKLVNQCYP GRT DKKPK SETSYLLYYVNSRR KLEKVS+YL+KRST+D
Sbjct: 5 MRMMFTPKHQKLVNQCYPTGRTTDKKPKSSETSYLLYYVNSRRSKLEKVSTYLIKRSTSD 64
Query: 61 LNRRRSGNVSVTLELLAKIVENCNENMNIFIKDFIHIMTLVLXXXXXXXDPTIVGLIERV 120
LN RR GN++VTL+L+ KIV +C EN+N+F+KDF++IM VL D ++V LIE
Sbjct: 65 LNHRRIGNIAVTLDLMNKIVLHCKENLNVFVKDFLYIMNKVLSNNNFNNDVSVVELIELA 124
Query: 121 LEAICNHLDGSLVSGDSEFLELFKNFVTLYFKVANTKLNDTDLVLKGCLDFSKISNLGSI 180
+IC +LD L +GD EF++L++NFV L+FK+ ++++ D++LK C+D S +++ S
Sbjct: 125 FSSICQNLDDVLCNGDMEFVQLYQNFVDLFFKIVTERIHNDDMLLKCCIDISNTNSVSSN 184
Query: 181 HQWSATAKNCVSIALTKFQERHPIYSEATIDSSFSEPGSPALKKKLTRTQTKVMGLDDVS 240
Q + V+ ++KFQER+P + +++++ L K+L+RTQT+ +GLD +
Sbjct: 185 PQLNHFVSKSVAYTISKFQERNPKFKTLSLEAALES----NLGKRLSRTQTRTIGLDKAA 240
Query: 241 -NTGDYSILALNTFFNTTETDKLTIGLHALIEHLLETPNKELLQFICNGIPVQLRYIVIL 299
+ D S+ AL ++FNTTETDKL + + L+ L TPNKELL+F+CNGIPVQLRYIVIL
Sbjct: 241 EDNHDLSVKALQSYFNTTETDKLNLSIRTLLRCLQSTPNKELLEFVCNGIPVQLRYIVIL 300
Query: 300 LFVRPLGTSSEK-NMXXXXXXXXXXXTSAVSIIGLSVIDILRRLITVQLAKSDSTTVVKQ 358
L VR L + N S VSI+GLSV+DI+R+L+ QL + + VV Q
Sbjct: 301 LLVRQLSDKDKNVNPIVSLKLMSSLLVSDVSIVGLSVLDIMRKLLNFQLKNATNKEVVAQ 360
Query: 359 IAVTIKDLNRKTYYKQQSSDMFAELSFKF-IESGKPHHLELFQLDLDSLISVTSDQCLDL 417
+T+ DLN KTYY +Q+SDM EL K ++ K D+D L+ + + L
Sbjct: 361 SCITMTDLNHKTYYAEQTSDMLYELLLKLKSDTVKDVEKNAVVEDIDFLVEHITQPSISL 420
Query: 418 DLFGEFLPYVTDK-TQLSKLLYPEAPHQVIFIRFFEKVSTLSKQDTEIAISTS-FAYYKA 475
+LF + Y+ + L ++ E P ++F + + + L + + F Y
Sbjct: 421 ELFIDLAHYMKNHIICLFNIVETEVPSSILFSKLYSLLRELDSHGVQKEMMEEIFDKYGK 480
Query: 476 ASLLSGLAYYVNN-NRPSDGYYAYHHHASKFLGLADYQTQVEFKRKDNDIFTKEDLLNYY 534
+LLSGL Y++ N + P YY+YH A+ FL L DY++Q E+K + +FTKEDLL+YY
Sbjct: 481 MALLSGLNYFLENVSEPEYTYYSYHLQAANFLKLNDYKSQTEYKMQTRTLFTKEDLLSYY 540
Query: 535 SDAGSNIYSEKGRDILLVDHSDQNGTDIDQDTVRYSTPIPLPQISIPPTTTNGIGIKKSS 594
SD GSN YS+KG ILL + + +D+ D+ +TP+ + +NG + ++
Sbjct: 541 SDTGSNKYSKKGAQILLSRDNQISTSDLLSDSQVRTTPLEYKNVP-NAIFSNGKAVYDNN 599
Query: 595 ------------------PANDTYVT----------------RSLK--HNPVPNVKDLKN 618
ANDT ++ RS K P V DLK
Sbjct: 600 DFAAKQNKFDNSIDDNIEEANDTVISDANAKGSIYRFVAEDARSWKTMRATAPKVSDLKK 659
Query: 619 LVSSKKDKSNTK---TLRGSQSVKSKVTNITFLLDELKNDGDEI-KIADPDEEDIIGMEK 674
++ K +N K + RGSQSVKS+VTNITFLL+ELK D+ KI DPDEE+I+G++K
Sbjct: 660 TMNEKNIPNNMKRDGSFRGSQSVKSRVTNITFLLNELKTFSDDANKIKDPDEENIVGLDK 719
Query: 675 QDLARSYSLRMNTISST-------NSRTLIPSVENAEEHGDDFRDAHEDIEVSSSTRGRL 727
D+ARS SLR+ ISS N ++ + E DDF+DA+ED+ S S+RG++
Sbjct: 720 IDVARSNSLRLAPISSLSDRSSIGNRKSFLQKTATGENQNDDFKDANEDLH-SLSSRGKI 778
Query: 728 F 728
F
Sbjct: 779 F 779
>SPCC794.08 [R] KOG1877 Putative transmembrane protein cmp44E
Length = 798
Score = 89.7 bits (221), Expect = 1e-17
Identities = 114/439 (25%), Positives = 185/439 (41%), Gaps = 76/439 (17%)
Query: 1 MGFLFTPKHQKLVNQCYPPGRTPDKKPKGSETSYLLYYVNSRRPKLEKVSSYLVKRSTTD 60
M LF KH+KLV +C+P G+ + +P GS +YL YY S KL KV+ +L R
Sbjct: 1 MWLLFRSKHKKLVLRCFPSGKLGETEPNGSPLAYLSYYAASNSSKLRKVAHFLGSRVRHS 60
Query: 61 LNRRRSGNVSVTLELLAKIVENCNENMNIFIKDFIHIMTLVLXXXXXXXDPTIVGLIERV 120
+R V + L++ +V+ C +N+N+ + ++ ++L + ++
Sbjct: 61 YYHKRDNEVIIGLKICKTLVQKCRDNINVMASE---VVNMLLVASSSKNLEVLSACVDCF 117
Query: 121 LEAICNHLDGSLVSGDSEFLELFKNFVTLYFKVANTKLNDTDLVLKG--CLD--FSKISN 176
N GS + +EF F N V +F+++ KG C+D SK+
Sbjct: 118 ATFCDNSGKGSPATFGNEFHSAFNNLVNSFFELS-----------KGIDCVDPQQSKMLG 166
Query: 177 LGSIHQWSATAKNCVSIALTKFQERHPIYSEATIDSSFSEPGSPALKKK---LTRTQTKV 233
L + H +A K + ++Q I+ + +S+SE S KK L R+ K
Sbjct: 167 LKAFHALTA-CKFAGTEGGMRYQPHFAIH--CVLINSWSE--SDQEKKSFIDLVRSTAKS 221
Query: 234 MGLDDVSNTG-------------DYSI--LALNTFFNT-TETDKL-----TIGLHALIEH 272
S+TG D +I L + FN T+TD L T L
Sbjct: 222 YKPLPPSSTGVSLPEHDEAGDNIDVAIKKLCIRILFNIYTQTDPLFMAESTKSLIHFFAA 281
Query: 273 LLETP-NKELLQFICNGI----PVQLRYIVILLFVRPLGTS----SEKNMXXXXXXXXXX 323
+TP N E + + N I PV+LR+ + +R L +S SE N+
Sbjct: 282 KSDTPVNLEYISVVLNQILDWTPVELRHSIFFCCLRCLSSSRIVNSETNV-MVPYMIYSI 340
Query: 324 XTSAVSIIGLSVIDILRRL----------------ITVQLAKSDSTTVVKQ---IAVTIK 364
S SI GLSVID+LR L + +S S + ++ + V I
Sbjct: 341 LNSKNSISGLSVIDVLRDLGSHLINAVNSFDADDQTWYNMCESPSEKLPRRLYLLLVCIT 400
Query: 365 DLNRKTYYKQQSSDMFAEL 383
L + YY ++ +D++ E+
Sbjct: 401 CLTKHQYYDEEFADVWREI 419
>Hs14741682 [R] KOG1877 Putative transmembrane protein cmp44E
Length = 821
Score = 52.4 bits (124), Expect = 2e-06
Identities = 27/97 (27%), Positives = 57/97 (57%), Gaps = 3/97 (3%)
Query: 7 PKHQKLVNQCYPPGRTPDKKPKGSETSYLLYYVNSRRPKLEKVSSYLVKRSTTDLNRRRS 66
P++++LV+ +P P ++ L +Y S KL+++ SYL +R + D+ R RS
Sbjct: 14 PRYKRLVDNIFP--EDPKDGLVKTDMEKLTFYAVSAPEKLDRIGSYLAERLSRDVVRHRS 71
Query: 67 GNVSVTLELLAKIVENC-NENMNIFIKDFIHIMTLVL 102
G V + +E L +++ C ++++ F++ F+H++ +L
Sbjct: 72 GYVLIAMEALDQLLMACHSQSIKPFVESFLHMVAKLL 108
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.134 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,785,928
Number of Sequences: 60738
Number of extensions: 1824675
Number of successful extensions: 5648
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 5637
Number of HSP's gapped (non-prelim): 4
length of query: 730
length of database: 30,389,216
effective HSP length: 114
effective length of query: 616
effective length of database: 23,465,084
effective search space: 14454491744
effective search space used: 14454491744
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)