ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1801 good R KOG2220 General function prediction only Predicted signal transduction protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1801 639956 641911 652
(652 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR275c [R] KOG2220 Predicted signal transduction protein 425 e-119
HsM7019487 [R] KOG2220 Predicted signal transduction protein 121 3e-27
Hs20535508 [R] KOG2220 Predicted signal transduction protein 121 3e-27
Hs14736297_1 [R] KOG2220 Predicted signal transduction protein 118 2e-26
At1g15130 [R] KOG2220 Predicted signal transduction protein 105 2e-22
7301622 [R] KOG2220 Predicted signal transduction protein 105 2e-22
CE25075 [R] KOG2220 Predicted signal transduction protein 95 3e-19
YPL084w [R] KOG2220 Predicted signal transduction protein 83 2e-15
SPAC2G11.05c [R] KOG2220 Predicted signal transduction protein 77 6e-14
SPAC17G6.05c [R] KOG2220 Predicted signal transduction protein 72 2e-12
Hs19882237 [R] KOG2220 Predicted signal transduction protein 72 2e-12
7294357_1 [R] KOG2220 Predicted signal transduction protein 66 2e-10
Hs14916439 [R] KOG2220 Predicted signal transduction protein 59 2e-08
7293132 [R] KOG2220 Predicted signal transduction protein 55 3e-07
CE24434_1 [R] KOG2220 Predicted signal transduction protein 50 8e-06
>YOR275c [R] KOG2220 Predicted signal transduction protein
Length = 661
Score = 425 bits (1093), Expect = e-119
Identities = 233/659 (35%), Positives = 387/659 (58%), Gaps = 17/659 (2%)
Query: 1 MNDIFAIPFKRALQINLKDAFTVVINNTFYQTAASVEADLTQLDKYRDVLFHLDVCQADL 60
M+++ AIP KR L+++ + +I+ T +QTA+ ++D+ ++ R+ D+ L
Sbjct: 1 MSELLAIPLKRTLEVDFATELSKLIDTTSFQTASFFQSDILKVVDARNNAIAPDISIDGL 60
Query: 61 NMLKQYYMALKAIAVKLPDDQVEFTWFNTLGLKSSGMTRNSLRFETFNVLYNIGAMYSSL 120
+ LK+YY+ L + K P++Q+EFTWF TL KS G ++ SL++E ++YNIG MYS L
Sbjct: 61 SALKEYYVILLQLEKKFPNNQIEFTWFQTLSQKSRGTSQYSLQWEKLTIIYNIGCMYSLL 120
Query: 121 AVEQRLESTEGLKESCRLFKLSAGCFKFIYEHEVS-NNFKFFDEYTLNALVSMMLAQAQQ 179
A+ ++ E LK SC F+ +AGCFK + +H+ + D+ TLNAL S+MLAQAQ+
Sbjct: 121 ALNSNNDAAESLKTSCLYFQNAAGCFKHVLDHQKNLETIPVVDDATLNALTSLMLAQAQE 180
Query: 180 MVWKKACFDDIERHSILSRLALQVALFYQTASKNSNCSPYIRTDWVKSLTSKSHYFMAIA 239
W KA D + S++++L+ Q+ FY A ++ IR+DW+ L +K YF A+
Sbjct: 181 CFWFKAV-QDKHKDSLIAKLSQQIVDFYCEAINDAQRGKLIRSDWINHLKAKKAYFSAVT 239
Query: 240 YYRSGLHQVQKQNYAQGICDFQYALTWINKLSLDDELTEWRGEVQALLESAERDNDLIYL 299
YYR L +K+ + + Q L +IN+ +L + +++ V++ L+ A+RDN+ IYL
Sbjct: 240 YYRIALSFNEKKQFGNVVKALQMGLQFINESTLSSQ-AKFKTVVESSLKEAQRDNEFIYL 298
Query: 300 QASVQNPSKVKPVMMVQ----ADLFDEIEKKDGNIFKNLLPIDVLESCNAFNERVETYVK 355
Q +KP +MV+ A L I KKD +FK+L+PI+V+E C A+NER + YV+
Sbjct: 299 QEVPSELPSIKPALMVKPSSSATLLPSI-KKDETLFKDLIPIEVMEYCTAYNERQDEYVE 357
Query: 356 EHISNPLESMNKLLISNTPQYMDFKSYY-ISEQEWNSYSDSLQDLEQLRAYVAGELKLSE 414
+ ++NPL S+NKLL + + + +SE E + Y SL +L V +L E
Sbjct: 358 QRVTNPLASLNKLLKESLTTFQIPQGLTKVSEAELSHYQASLNNLLINNKNVQVQLDNIE 417
Query: 415 SILQKDIQENEQMIREHGLLRWKIPSKDKKIESLLADLTNIRNYIENGMKVDTETASLFK 474
IL ++ + Q+ +HG L W +P + L +R Y++ G +D +T LF+
Sbjct: 418 QILNEEAFTDNQLRLKHGTLNWTLPESSTTNTAYYEKLKKLRGYLDEGSAIDKQTNELFQ 477
Query: 475 TLDHDLVTNVSQPPESSDPIMKEASLILQGRKNHILAAERKIIENRLLPKIVSYYKKTGS 534
++D +L+ + + PES+DP+ + +I+Q R ++I RK E R+LPKI++ YKK G+
Sbjct: 478 SIDKNLIGSEIRLPESNDPLTNKIKMIIQERNDYIDRTRRKSSEYRILPKIITSYKKNGT 537
Query: 535 KDFEPVFQEHIRMFDGDLLQVQKEKAKNKEMLTKVTLSSP--------EQVQISRNDPRT 586
DFEP+F H++ FD DL V K +N +++ +V LS E ++ R DPR
Sbjct: 538 VDFEPIFIGHLKYFDEDLRYVNSTKEENIKLIEEVNLSKKNNPGRSGIEPKKMVRIDPRE 597
Query: 587 LYLEELKHSSNVLSELKENIISGKQFYQDLITALESKLKEIEDYVNERKLQRTELNDTL 645
LY+E+L++S +L E+KEN+ +G FY++LIT+ + E+++Y R+ ++ L+ +L
Sbjct: 598 LYIEDLRYSFKLLDEVKENLSAGTAFYENLITSTSNLYNEVQEYDTARRAEKARLDKSL 656
>HsM7019487 [R] KOG2220 Predicted signal transduction protein
Length = 868
Score = 121 bits (304), Expect = 3e-27
Identities = 165/714 (23%), Positives = 307/714 (42%), Gaps = 82/714 (11%)
Query: 1 MNDIFAIPFKRALQINLKDAFTVVINNTFYQTAASVEADLT----QLDKYRDVLFH--LD 54
M ++ K+ +++L I T Y + +A +L K R LD
Sbjct: 1 MATFISVQLKKTSEVDLAKPLVKFIQQT-YPSGGEEQAQYCRAAEELSKLRRAAVGRPLD 59
Query: 55 VCQADLNMLKQYYMALKAIAVKLPDDQ----VEFTWFNTL--GLKSSGMTR---NSLRFE 105
+ L L +YY + +I K P + + FTW + G G + SL +E
Sbjct: 60 KHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYE 119
Query: 106 TFNVLYNIGAMYSSLAVEQRLESTEGLKESCRLFKLSAGCFKFIYEHEVSNNFK----FF 161
VL+N A+ S +A EQ L++ EGLK + + ++ ++G F I E +S +
Sbjct: 120 KSCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDI 179
Query: 162 DEYTLNALVSMMLAQAQQMVWKKACFDDIERHSILSRLALQVALFYQTASKNSNCSPYIR 221
T+ L +MLAQAQ++ + KA D + + +I+++LA Q A ++ A K +
Sbjct: 180 SPDTVGTLSLIMLAQAQEVFFLKATRDKM-KDAIIAKLANQAADYFGDAFKQCQYKDTLP 238
Query: 222 TDWVKSLTSKSHYFMAIAYYRSGLHQVQKQNYAQGICDFQYALTWINKL-SLDDE---LT 277
+ L +K A A Y + Q++ + + I Q+A I + S DE +
Sbjct: 239 KEVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYVNVK 298
Query: 278 EWRGEVQALLESAERDNDLIYLQASVQNPSKVKPV----MMVQADLFDEIEKKDGNIFKN 333
++ ++ L +A++DND IY V + + P+ ++ + I +K ++F+
Sbjct: 299 DFSDKINRALTAAKKDNDFIY-HDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLFEK 357
Query: 334 LLPIDVLESCNAFNERVETYVKEHISNPLES---MNKLLIS-------------NTPQYM 377
++P+ V +S A+N+R V I+ E+ N +L S PQ +
Sbjct: 358 MVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQSI 417
Query: 378 DFKSYYISEQEWNSYSDSLQDLEQLRAYVAGELKLSESILQKDI------QENEQMIREH 431
KS + EQ +Q ++QL + L+ + IL + + + + +R
Sbjct: 418 LTKSRSVIEQ------GGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAK 471
Query: 432 GLLRWKIPSKDKKIESLLADLTNIRNYIENGMKVDTETASLFKTLDHDLVTNVSQPPE-- 489
RW+ ++ + L A+ TN R ++ ++ D + +++ +V PE
Sbjct: 472 FKERWQRTPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELN 531
Query: 490 ----SSDPIM----KEASLILQGRKNHI--LAAERKIIENRL-------LPKIVSYYKKT 532
S++P E +L+ +++ + ER+ +EN L K ++ +
Sbjct: 532 AAIPSANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQD 591
Query: 533 GSKDFEPV-FQEHIRMFDGDLLQVQKEKAKNKEMLTKVTLSSPEQVQISR-NDPRTLYLE 590
G + E + E R++ G +VQ+ K + +L + +S E ++ + N+ L E
Sbjct: 592 GVINEEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREE 651
Query: 591 ELKHSSNVLS---ELKENIISGKQFYQDLITALESKLKEIEDYVNERKLQRTEL 641
LK+ + EL N+ G +FY +L L + D V RK +R EL
Sbjct: 652 VLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDEL 705
>Hs20535508 [R] KOG2220 Predicted signal transduction protein
Length = 868
Score = 121 bits (304), Expect = 3e-27
Identities = 165/714 (23%), Positives = 307/714 (42%), Gaps = 82/714 (11%)
Query: 1 MNDIFAIPFKRALQINLKDAFTVVINNTFYQTAASVEADLT----QLDKYRDVLFH--LD 54
M ++ K+ +++L I T Y + +A +L K R LD
Sbjct: 1 MATFISVQLKKTSEVDLAKPLVKFIQQT-YPSGGEEQAQYCRAAEELSKLRRAAVGRPLD 59
Query: 55 VCQADLNMLKQYYMALKAIAVKLPDDQ----VEFTWFNTL--GLKSSGMTR---NSLRFE 105
+ L L +YY + +I K P + + FTW + G G + SL +E
Sbjct: 60 KHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYE 119
Query: 106 TFNVLYNIGAMYSSLAVEQRLESTEGLKESCRLFKLSAGCFKFIYEHEVSNNFK----FF 161
VL+N A+ S +A EQ L++ EGLK + + ++ ++G F I E +S +
Sbjct: 120 KSCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDI 179
Query: 162 DEYTLNALVSMMLAQAQQMVWKKACFDDIERHSILSRLALQVALFYQTASKNSNCSPYIR 221
T+ L +MLAQAQ++ + KA D + + +I+++LA Q A ++ A K +
Sbjct: 180 SPDTVGTLSLIMLAQAQEVFFLKATRDKM-KDAIIAKLANQAADYFGDAFKQCQYKDTLP 238
Query: 222 TDWVKSLTSKSHYFMAIAYYRSGLHQVQKQNYAQGICDFQYALTWINKL-SLDDE---LT 277
+ L +K A A Y + Q++ + + I Q+A I + S DE +
Sbjct: 239 KEVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYVNVK 298
Query: 278 EWRGEVQALLESAERDNDLIYLQASVQNPSKVKPV----MMVQADLFDEIEKKDGNIFKN 333
++ ++ L +A++DND IY V + + P+ ++ + I +K ++F+
Sbjct: 299 DFSDKINRALAAAKKDNDFIY-HDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLFEK 357
Query: 334 LLPIDVLESCNAFNERVETYVKEHISNPLES---MNKLLIS-------------NTPQYM 377
++P+ V +S A+N+R V I+ E+ N +L S PQ +
Sbjct: 358 MVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQSI 417
Query: 378 DFKSYYISEQEWNSYSDSLQDLEQLRAYVAGELKLSESILQKDI------QENEQMIREH 431
KS + EQ +Q ++QL + L+ + IL + + + + +R
Sbjct: 418 LTKSRSVIEQ------GGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAK 471
Query: 432 GLLRWKIPSKDKKIESLLADLTNIRNYIENGMKVDTETASLFKTLDHDLVTNVSQPPE-- 489
RW+ ++ + L A+ TN R ++ ++ D + +++ +V PE
Sbjct: 472 FKERWQRTPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELN 531
Query: 490 ----SSDPIM----KEASLILQGRKNHI--LAAERKIIENRL-------LPKIVSYYKKT 532
S++P E +L+ +++ + ER+ +EN L K ++ +
Sbjct: 532 AAIPSANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQD 591
Query: 533 GSKDFEPV-FQEHIRMFDGDLLQVQKEKAKNKEMLTKVTLSSPEQVQISR-NDPRTLYLE 590
G + E + E R++ G +VQ+ K + +L + +S E ++ + N+ L E
Sbjct: 592 GVINEEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREE 651
Query: 591 ELKHSSNVLS---ELKENIISGKQFYQDLITALESKLKEIEDYVNERKLQRTEL 641
LK+ + EL N+ G +FY +L L + D V RK +R EL
Sbjct: 652 VLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDEL 705
>Hs14736297_1 [R] KOG2220 Predicted signal transduction protein
Length = 1189
Score = 118 bits (296), Expect = 2e-26
Identities = 151/711 (21%), Positives = 299/711 (41%), Gaps = 87/711 (12%)
Query: 7 IPFKRALQINLKDAFTVVINNTFYQTAASVEADLTQLDKYRDVLFHLDVCQADLNMLKQY 66
+ K A + + A + + + + +L +L+ R + ++L++Y
Sbjct: 12 LDLKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRKY 71
Query: 67 YMALKAIAVKLP-----DDQVEFTWFNTLGLKSSGMTRNSLRFETFNVLYNIGAMYSSLA 121
L + ++P + V TW KS + +++E +LYN+GA++S L
Sbjct: 72 LGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS--VAHEDIKYEQACILYNLGALHSMLG 129
Query: 122 VEQRLESTEGLKESCRLFKLSAGCFKFIYEHEVSNNFKFFDEYTLNALVSMMLAQAQQMV 181
+ S EG+K SC F+ +AG F ++ EH L V++ML QAQ+ +
Sbjct: 130 AMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLMLGQAQECL 189
Query: 182 WKKACFDDIERHSILSRLALQVALFYQTASK------NSNCSPYIRTDWVKSLTSKSHYF 235
+K+ D+ + +++R++ QV +Y+ A + ++ I+ DW K + K +YF
Sbjct: 190 LEKSMLDN-RKSFLVARISAQVVDYYKEACRALENPDTASLLGRIQKDWKKLVQMKIYYF 248
Query: 236 MAIAYYRSGLHQVQKQNYAQGICDFQYALTWINKL---------SLDDELTEWRGEVQAL 286
A+A+ G ++Q + + + FQ AL +N+ ++ D L +
Sbjct: 249 AAVAHLHMGKQAEEQQKFGERVAYFQSALDKLNEAIKLAKGQPDTVQDALRFTMDVIGGK 308
Query: 287 LESAERDNDLIYLQA--------SVQNPSKVKPVMMVQADLFDEIEKKDGNIFKNLLPID 338
SA++DND IY +A V+ VKP+ + D + D IF L+P+
Sbjct: 309 YNSAKKDNDFIYHEAVPALDTLQPVKGAPLVKPLPVNPTD--PAVTGPD--IFAKLVPMA 364
Query: 339 VLESCNAFNERVETYVKEHISNPLESMNKLL------ISNTPQYMDFKSYY--ISEQEWN 390
E+ + ++E ++E ++ +E N++L + P+ +D Y I Q
Sbjct: 365 AHEASSLYSEEKAKLLREMMAK-IEDKNEVLDQFMDSMQLDPETVDNLDAYSHIPPQLME 423
Query: 391 SYS------DSLQDLEQLRAYVAGELKLSESILQKDIQENEQMIREHGLLRWKIPSKDKK 444
+ D++++L Q ++G E+ L KDI++ ++ E LL K +
Sbjct: 424 KCAALSVRPDTVRNLVQSMQVLSGVFTDVEASL-KDIRD---LLEEDELLEQKFQEAVGQ 479
Query: 445 IESL----LADLTNIRNYIENGMKVDTETASLFKTLDHDLVTNVSQPPESSDP------- 493
++ A+L +R M+V + + L + +V S P
Sbjct: 480 AGAISITSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVGNLRLLSGPLDQVRAA 539
Query: 494 -----IMKEASLILQGRKNHILAAERKIIENR---------LLPK--IVSYYKKTGSKDF 537
+ E +LQ K ILA +++ + R L+ K I + T +
Sbjct: 540 LPTPALSPEDKAVLQNLK-RILAKVQEMRDQRVSLEQQLRELIQKDDITASLVTTDHSEM 598
Query: 538 EPVFQEHIRMFDGDLLQVQKEKAKNKEMLTKVTLSSPEQVQISR-----NDPRTLYLEEL 592
+ +F+E ++ +D + +++ A +L +T ++ + + R + L+ L
Sbjct: 599 KKLFEEQLKKYDQLKVYLEQNLAAQDRVLCALTEANVQYAAVRRVLSDLDQKWNSTLQTL 658
Query: 593 KHSSNVLSELKENIISGKQFYQDLITALESKLKEIEDYVNERKLQRTELND 643
S +L + G+ FY DL + + + L+ + R+ R +L D
Sbjct: 659 VASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAREAARQQLLD 709
>At1g15130 [R] KOG2220 Predicted signal transduction protein
Length = 846
Score = 105 bits (263), Expect = 2e-22
Identities = 153/729 (20%), Positives = 304/729 (40%), Gaps = 119/729 (16%)
Query: 2 NDIFAIPFKRALQINLKDAFTVVINNTFYQTAAS-VEADLTQLDKYRDVLFHLDVCQ--A 58
N + AI K+ ++L + T+ + A ++ DL L + R + + A
Sbjct: 8 NLMLAIHEKKTSSVDLYRPLRNYVTFTYSEREAQLIDDDLETLKQLRSDIERVSDPSPAA 67
Query: 59 DLNMLKQYYMALKAIAVKLPD-------DQVEFTWFNTLGLKSSGMTRNSLRFETFNVLY 111
++L YY L + + P + V F W++ K T+ ++ E VL+
Sbjct: 68 RRDLLISYYKVLCLVETRFPISPDKDHVNAVSFVWYDAFKQKHKA-TQQNIHLEKAAVLF 126
Query: 112 NIGAMYSSLAVEQRLESTEGLKESCRLFKLSAGCFKFIYEHEVSNNFKFFDEYTLNALVS 171
N+GA YS + + + +G +++ F +AG F + ++E S T++ V
Sbjct: 127 NLGASYSQIGLGHDRTTVDGRRQASHAFMAAAGAFAHLRDNE-SIKATIGPSTTVDVSVE 185
Query: 172 -------MMLAQAQQMVWKKACFDDIERHSILSRLALQVALFYQTASKNSNCSP---YIR 221
+M+AQAQ+ V++ + +++A QV +FY+ A SP +
Sbjct: 186 CVGMLERLMVAQAQECVFENTIAKG-STPGVSAKIARQVGIFYEEALSALIISPLKDHFD 244
Query: 222 TDWVKSLTSKSHYFMAIAYYRSGLHQVQKQNYAQGICDFQYALTWINK---------LSL 272
W+ + K+ F A +R G +K+ A+ I + + + + L
Sbjct: 245 KGWISHVQLKAALFYGEACFRYGKELHEKEEIAEEIARLRSGASRLAEAKKSSRGAPAQL 304
Query: 273 DDELTEWRGEVQALLESAERDNDLIYLQASVQNPSKVKPV----MMVQADLFDEIEKKDG 328
+ + + L+ A ++ND +YL V +PS + P+ M+ ++ D ++
Sbjct: 305 IEAMNTLESSINGNLDRAVKENDRVYLM-RVPSPSSLSPLPAFSMVKPMNMTDILDASKE 363
Query: 329 NIFKNLLPIDVLESCNAFNERVETYVKEHISNPLESMNKL----------------LISN 372
+F L+P ++ + + E V+ ++ + L+ ++L + N
Sbjct: 364 KMFSILVPDSSAKALSRYTEMVDDVIRTQ-AERLQQASELTRVRLKEMDLPDSILAVDGN 422
Query: 373 TPQYMDFKSYYISEQEWNSYSDSLQDLEQLRAYVAGELKL---SESILQKDIQENEQMIR 429
+ +D K + Q + +L+QLR +L +E +LQK+ E+ Q
Sbjct: 423 SALPVDLKEDVEAVQISGGPAGLEAELQQLRDLKRVNQELLVHTEELLQKEATEDSQFRS 482
Query: 430 EHGLLRWKIPSKDKKIESLLADL----TNIRNYIENGMKVD---TETASLFKTLDHDLVT 482
+ G RW P ++L L N++ E+ +K++ + ++L LD
Sbjct: 483 QFG-TRWTRPQSSTLTKNLQDRLNRFAANLKQAGESDVKIERSVRDNSALMSILDR---- 537
Query: 483 NVSQPPESSDPIMKEASLILQGRKNHI-------------LAAERKIIENRL-------- 521
+P ES+ P + + L ++ I L A+R +E+ L
Sbjct: 538 ---RPIESAVPTLARPIMSLDATEDAIVGTLKQSLRQLENLGAQRAGLEDMLKEMKRKDD 594
Query: 522 -LPKIVSYYKKTGSKDFEPVFQEHIRMFDGDLLQVQKEKAKNKEMLTKVTLSSPEQVQIS 580
LPK+++ TGS +E +F++ I +D + ++ ++N E+ ++ + Q+Q
Sbjct: 595 ILPKLMTI---TGS--YEDMFRKEISKYD----HICEDISQNIEVQEQLLM----QIQAQ 641
Query: 581 RNDPRTLY-LEELKHSSN-----------VLSELKENIISGKQFYQDLITALESKLKEIE 628
+ T++ LE+ K S E+KENI G +FY L A+ + ++
Sbjct: 642 NEEFSTIFNLEDYKASKEKCYKQIQAAIMKYREIKENINEGLKFYVTLQDAITNVKQQCS 701
Query: 629 DYVNERKLQ 637
D+V R +Q
Sbjct: 702 DFVMTRSIQ 710
>7301622 [R] KOG2220 Predicted signal transduction protein
Length = 836
Score = 105 bits (262), Expect = 2e-22
Identities = 151/726 (20%), Positives = 294/726 (39%), Gaps = 88/726 (12%)
Query: 1 MNDIFAIPFKRALQINLKDAFTVVINNTFYQTAASVEAD-----LTQLDKYRDVLF--HL 53
M+ +P K+ ++++ +I +T Y A+ E + + K R+
Sbjct: 1 MSKFLGVPLKKPSEVDVIKPLNNLIQST-YNGASEEEKGKYGEAVNEFSKQRNTAIWKFF 59
Query: 54 DVCQADLNMLKQYYMALKAIAVKLP--DDQVEFTWFNTLGLKSS-----GMTRNSLRFET 106
+ +A L ++ YY + A+ K+ + Q+ F W + S +T SL +E
Sbjct: 60 EKYEASLEIVYAYYDQICALETKISVSELQIPFKWKDAFDKGSIFGGKISLTHTSLLYEK 119
Query: 107 FNVLYNIGAMYSSLAVEQRLESTEGLKESCRLFKLSAGCFKFIY----EHEVSNNFKFFD 162
VL+NI A+ S++A Q L+S +GLK + +L + SAG F+++ S
Sbjct: 120 VCVLFNIAALQSNIAANQSLDSDDGLKLTIKLLQQSAGIFQYLKGATPAAVPSEPTPDLS 179
Query: 163 EYTLNALVSMMLAQAQQMVWKKACFDDIERHSILSRLALQVALFYQ---TASKNSNCSPY 219
+ TL L ++M+AQAQ++ KA D++ + I+++L Q Y A + +
Sbjct: 180 QDTLTVLQALMVAQAQEVFILKAIKDNL-KDQIIAKLCCQAEESYADVLRAMQKESVRSL 238
Query: 220 IRTDWVKSLTSKSHYFMAIAYYRSGLHQVQKQNYAQGICDFQYALTWI----NKLSLDDE 275
+W+ ++ K F A+ L + + I + A+ + +
Sbjct: 239 WEKEWIPTIAGKQAGFHALTQLYQSLVCRAAKKIGEEIARLRNAIDLFKAAQTRSGNETY 298
Query: 276 LTEWRGEVQALLESAERDNDLIYLQ-----ASVQNPSKVK-----PVMMVQADLFDEIEK 325
L E+ + L + +DN+ IY + +++ +P K + P+ + A+ F +
Sbjct: 299 LDEYFSRAKRNLTESTKDNEFIYNEIIPELSTLTSPGKAQLAKPLPIAVPLAENFKD--- 355
Query: 326 KDGNIFKNLLPIDVLESCNAFNERVETYVKEHI---SNPLESMNKLLI------------ 370
IF +L+P+++ + A + R V I +++N +L
Sbjct: 356 ----IFSSLVPVELHRALTASDMRRNEIVNVEIMKLREATQTLNAVLASLNLPAAVETAD 411
Query: 371 --SNTPQYMDFKSYYISEQEW-NSYSDSLQDLEQLRAYVAGELKLSESILQKDIQENEQM 427
S P + K+ + ++ + L+DL +L L +E +L ++ ++++
Sbjct: 412 GNSGLPPSLKEKANEVRQKGGIENVQTMLKDLPELLNRNREILDETERLLDEE-RDSDNQ 470
Query: 428 IREHGLLRWKIPSKDKKIESLLADLTNIRNYIENGMKVDTETASLFKTLDHDLVTNVSQP 487
+R RW S DK E + R I N ++ D F+ + + +S P
Sbjct: 471 LRAQFKDRWTRISSDKLTEMFRTNAKKYREVITNAIEADKVVRQKFEA-NQKGIQLLSLP 529
Query: 488 PESSDPIMKEASLILQGRKNHI------------LAAERKIIENRL-------LPKIVSY 528
P+ + AS + + + + AER+ IE+ L + +
Sbjct: 530 PDQIQQSLPSASGSVDPNCSSVQRLKKLMDDVETIKAEREAIESELKGATFNMKDEFLIA 589
Query: 529 YKKTGSKDFEPVFQEHIRMFDGDLLQVQKEKAKNKEMLTKVTLSSPEQVQISR----NDP 584
+K G+ D + I L Q +E + ++ L + S +S
Sbjct: 590 LQKDGAIDEPALSLARIGQVLNPLQQQVRESVERQQSLVS-EIQSAHGAFVSETGSCGSS 648
Query: 585 RTLYLEELKHSSNVLSELKENIISGKQFYQDLITALESKLKEIEDYVNERKLQRTELNDT 644
R +EL + + EL N+ G +FY DL L +I D+V RK ++ EL
Sbjct: 649 RDTLYQELATAFDSYIELSGNLQEGTKFYNDLTQLLVVFQNKISDFVFARKTEKEELLKD 708
Query: 645 LLCDTN 650
L +++
Sbjct: 709 LTTESS 714
>CE25075 [R] KOG2220 Predicted signal transduction protein
Length = 861
Score = 95.1 bits (235), Expect = 3e-19
Identities = 162/716 (22%), Positives = 301/716 (41%), Gaps = 96/716 (13%)
Query: 8 PFKRALQINLKDAFTVVINNTFYQTAASVEADLTQ----LDKYRDVLF--HLDVCQADLN 61
P K +++L T I+N Y T+ + +D+ + L+K R LD Q+ L+
Sbjct: 10 PLKSTNEVDLVKPLTSYIDNV-YNTSDNNRSDVAEAVQELNKLRSKACCQPLDKHQSALD 68
Query: 62 MLKQYYMALKAIAVKL----PDDQVEFTWFNTLGLKSSGMTRNSLR-----FETFNVLYN 112
+L +YY L AI K+ + V F W + S +R SL FE VL+N
Sbjct: 69 VLTRYYDQLVAIENKIIISATQNPVVFKWKDAFDKGSLFSSRASLSLSDGSFERAAVLFN 128
Query: 113 IGAMYSSLAVEQRLESTEGLKESCRLFKLSAGCFKFI-------YEHEVSNNFKFFDEYT 165
IG++ S + Q+ + + +K S +LF+ SAG F + + E + + T
Sbjct: 129 IGSLMSQIGAAQQFHTDDEIKVSAKLFQQSAGVFARLRDVVLGMVQQEPTPDLM---PDT 185
Query: 166 LNALVSMMLAQAQQMVWKKACFDDIERHSILSRLALQVALFYQTASKNSNCSPYIR---- 221
L AL ++M AQAQ+ ++ K D ++ S++ +++ QVA FY A K + +R
Sbjct: 186 LAALSALMTAQAQEAIYIKGHKDKMKATSMV-KISAQVAEFYSEAQKMMS-KDIVRGLWD 243
Query: 222 TDWVKSLTSKSHYFMAIAYYRSG-----LHQVQKQ--NYAQGICDFQYALTWINKLSLDD 274
DW ++ K+ + A+A Y Q+ +Q A+ + F A ++ + D
Sbjct: 244 KDWSAIVSGKNLAYQALAQYHQSEVCGEARQIGEQLSRLAESLKLFDTAQKYLPR----D 299
Query: 275 ELTEW--RGEVQALLESAERDNDLIYLQASVQ---NPSKVKPVMMVQADLFDEIEKKDGN 329
W V +A++DND IY + P+ K V+ + + +
Sbjct: 300 ITGIWDIYPSVSKAHAAAKKDNDFIYHEKVSDFRTLPTLPKAVLAKPTPMQTPMTPSFRD 359
Query: 330 IFKNLLPIDVLESCNAFNERVETYVKEHISNPLES---MNKLLIS--------------N 372
+F L+P+ V + +++ R V E+ MN +L S
Sbjct: 360 MFAVLVPVQVHNAMQSYDARKAELVNMETVRMREATQLMNGVLASLNLPAALDDVTSTET 419
Query: 373 TPQYMDFKSYYISEQEWNSYSDSLQDL--EQLRAYVAGELKLSES--ILQKDIQENEQMI 428
P+ + KS + + N S + L E Y E L+E+ IL ++ + ++ M
Sbjct: 420 LPESLKLKSAKLKQ---NGGSSEIMRLFSELPTLYQRNEDILTETSRILNEEKESDDTMR 476
Query: 429 REHGLLRWKIPSKDKKIESLLADLTNIRNYIENGMKVDTETASLFKTLDH--DLVTNVSQ 486
++ G +W S ++ L+ ++ R + D F++ +L++
Sbjct: 477 KQLG-TKWTRMSSEQLTGPLVTEIGKYRGILHTASNADKMVKEKFESHRQGIELLSKNES 535
Query: 487 PPESSDP-----IMKEASLILQGRKN----HILAAERKIIENRLLP---KIVSYYKKTGS 534
SS P E + Q R+ + + +R+++E L I + + K +
Sbjct: 536 ELRSSIPGQTAHATGETDTVRQLRQFMSQWNEVTTDRELLEKELKNTNCDIANDFLKAMA 595
Query: 535 K----DFEPVFQEHIRMFDGDL-LQVQKEKAKNKEMLTKVTLS----SPEQVQISRNDPR 585
+ + E + +E I GDL +VQ + ++ ++ + + E+ S R
Sbjct: 596 ENQLINEEHISKEKIAQIFGDLKRRVQSSLDTQETLMNQIQAANNTFTGEKTGSSTGAER 655
Query: 586 TLYLEELKHSSNVLSELKENIISGKQFYQDLITALESKLKEIEDYVNERKLQRTEL 641
L+ L +S+ ELK N+ G +FY DL L +++ D+ R+ ++ +L
Sbjct: 656 ERILKMLAQASDAYVELKANLEEGTKFYNDLTPILVRLQQKVSDFAFARQTEKEDL 711
>YPL084w [R] KOG2220 Predicted signal transduction protein
Length = 844
Score = 82.8 bits (203), Expect = 2e-15
Identities = 130/698 (18%), Positives = 287/698 (40%), Gaps = 98/698 (14%)
Query: 1 MNDIFAIPFKRALQINLKDAFTVVINNTFYQTAASVEADLTQLDKYRDVLFHLDVCQADL 60
+ D + +K+ L LK ++ TFY A+ E D + + L + + +L
Sbjct: 10 LKDTEKLDWKKGLSSYLKKSYGSSQWRTFYDEKATSELDHLR-NNANGELAPSSLSEQNL 68
Query: 61 NMLKQYYMALKAIAVKLPDD----QVEFTWFN---TLGLKSSGMTRNSLRFETFNVLYNI 113
+YY L+ + +L +++FTW++ + K T+++L FE L+NI
Sbjct: 69 ----KYYSFLEHLYFRLGSKGSRLKMDFTWYDAEYSSAQKGLKYTQHTLAFEKSCTLFNI 124
Query: 114 GAMYSSLAVEQRLESTEGLKESCRLFKLSAGCFKFIYEHEVSNNFKFFDEYTLNALVSMM 173
+++ +A E E K S + CF+++ E+ +++ L ++
Sbjct: 125 AVIFTQIAREN---INEDYKNSIANLTKAFSCFEYLSENFLNSPSVDLQSENTRFLANIC 181
Query: 174 LAQAQQMVWKKACFDDI--ERHSILSRLALQVALFYQTASK-----NSNCSPYIRTDWVK 226
A+AQ++ K D I ++++++S+L+ +Q + + + Y W
Sbjct: 182 HAEAQELFVLKLLNDQISSKQYTLISKLSRATCNLFQKCHDFMKEIDDDVAIYGEPKWKT 241
Query: 227 SLTSKSHYFMAIAYYRSGLHQVQKQNYAQGICDFQYAL-TWINKLSLDDELTE------W 279
++T K H++ +++ Y GLH ++ + I +++ I+ L L E +
Sbjct: 242 TVTCKLHFYKSLSAYYHGLHLEEENRVGEAIAFLDFSMQQLISSLPFKTWLVEFIDFDGF 301
Query: 280 RGEVQALLESAERDNDLIYLQA--SVQNPSKVKPVMMVQADLFD--------EIEKKDGN 329
+ ++ + +DND IY ++ +V +K + +++ ++ ++ K +
Sbjct: 302 KETLEKKQKELIKDNDFIYHESVPAVVQVDSIKALDAIKSPTWEKILEPYMQDVANKCDS 361
Query: 330 IFKNLLPIDVLESCNAFNERVETYVKEHISNP----LESMNKLLISNTPQYM-DFKSYYI 384
+++ ++P+DV E + ++E T +++ + LE + + +N P+ + D + +
Sbjct: 362 LYRGIIPLDVYEKESIYSEEKATLLRKQVEETETANLEYSSFIEFTNLPRLLSDLEKQF- 420
Query: 385 SEQEWNSYSDSLQDLEQLRAYVAGELKLSESILQKDIQENEQMIREHGLLRWKIPSKDKK 444
+ N +S++ + +R + K ++ +DI+E KI K K+
Sbjct: 421 --SDGNIFSNTDTQGQLMRDQIQTWCKFIQTNEFRDIEEQMN----------KIVFKRKQ 468
Query: 445 IESLLADLTNIRNYIENGMKVDTETAS-----LFKTLDHDLVT----------------- 482
I +L+ L N + +K AS LF + +V
Sbjct: 469 ILEILSALPNDQKENVTKLKSSLVAASNSDEKLFACVKPHIVEINLLNDNGKIWKKFDEF 528
Query: 483 NVSQPPESS---------DPIMK---------EASLILQGRKNHILAAERKIIENRLLPK 524
N + PP+ S D I++ E L+ ++ L+ R I N + K
Sbjct: 529 NRNTPPQPSLLDIDDTKNDKILELLKQVKGHAEDLRTLKEERSRNLSELRDEINNDDITK 588
Query: 525 IVSYYKKTGSKDFEPVFQEHIRMFDGDLLQVQKEKAKNKEMLTKVTLSSPEQVQISRNDP 584
++ K + + +F+ + F+ +++ K M+ + E +S
Sbjct: 589 LLIINKGKSDVELKDLFEVELEKFEPLSTRIEATIYKQSSMIDDIKAKLDEIFHLSNFKD 648
Query: 585 RTLYLEE-LKHSSNVLSELKENIISGKQFYQDLITALE 621
++ E+ L+ N +L+E + S F DL +E
Sbjct: 649 KSSGEEKFLEDRKNFFDKLQEAVKSFSIFASDLPKGIE 686
>SPAC2G11.05c [R] KOG2220 Predicted signal transduction protein
Length = 701
Score = 77.4 bits (189), Expect = 6e-14
Identities = 74/287 (25%), Positives = 123/287 (42%), Gaps = 27/287 (9%)
Query: 60 LNMLKQYYMALKAIAVK-LPDDQVEFTWFNTLGLKSSGMTRNS---LRFETFNVLYNIGA 115
L+ + Y+ L + K L + F W L SS R S L FE ++Y +
Sbjct: 58 LSSFQTYHQLLCVLEQKHLSECVAPFVWT----LSSSSNERESFENLIFEHACLIYRLAC 113
Query: 116 MYSSLAVEQRLESTEGLKESCRLFKLSAGCFKFIYEHEVSNNFKFFDEYTLNALVSMMLA 175
Y + A+ E L ++C+ F+LSAGCF++I + + F+E L A LA
Sbjct: 114 TYHTTAISLCNEKPPNLVQACQYFQLSAGCFRYINDFYIYTKSLDFNENLLKAWEIYCLA 173
Query: 176 QAQQMVWKKACFDDIERHSILSRLALQVALFYQTA---SKNSNCSPYIRTDWVKSLTSKS 232
+AQ ++ KA +D SI+ ++ +V L Y+ A KN+ +P I W +
Sbjct: 174 EAQTCIFSKANSNDTTSESIIVKILAKVFLLYEDAYKLFKNATGAPSIFVHWT---YIQK 230
Query: 233 HYFMAIAYYRSGLHQVQKQNYAQGICDFQYALTWINK-----------LSLDDELTEWRG 281
++ I Y Y + I + +L + + + ++L +
Sbjct: 231 LFYQTITYQIISRTSYSLNKYGENISYLRLSLLHCKEALKTRFDFGFNVKVYEKLEKLES 290
Query: 282 EVQALLESAERDNDLIYLQASVQNPS--KVKPVMMVQADLFDEIEKK 326
+Q L+ ERDND I+LQ + S + V MVQ+ D + K
Sbjct: 291 SLQFELKRNERDNDFIHLQPEIPVGSFPLLDTVTMVQSITPDVLTDK 337
>SPAC17G6.05c [R] KOG2220 Predicted signal transduction protein
Length = 775
Score = 72.4 bits (176), Expect = 2e-12
Identities = 149/749 (19%), Positives = 289/749 (37%), Gaps = 127/749 (16%)
Query: 19 DAFTVVINNTFYQTAASVEADLTQLDKYRDVLFHLDVCQADLNMLKQYYMALKAIAVKLP 78
+ FT ++ Y + VE + + R+ +D A ++L YY L ++ + P
Sbjct: 23 EPFTTFVSR-IYGNSVDVEDQIKAFNTLRENAADVDDTVAGKDILYSYYGQLDYLSFRFP 81
Query: 79 DD----QVEFTWFNTLGLKSSGMTRNSLRFETFNVLYNIGAMYSSLAVEQRLEST-EGLK 133
+ F W + L + + ++SL FE +VL+N+ ++ S +A T + K
Sbjct: 82 TGGNGINISFEWSDILDPDADFVKQSSLAFEKASVLFNLVSLLSRMAANHASAYTVDDYK 141
Query: 134 ESCRLFKLSAGCFKFIYEHEVSNNFKFFDEYTLNALVSMMLAQAQQMVWKKACF---DDI 190
+ + ++G K + E + + D L + ++ L QAQ+ V F D
Sbjct: 142 AAANCLQCASGIAKLLRESFIHAPGRDLDSNFLLGIYNLFLGQAQECVLGHMSFSASDSN 201
Query: 191 ERHSILSRLALQVALFYQTA-----SKNSNCSP-YIRTDWVK--SLTSKSHYFMAIAYYR 242
+S+ +++A A Y + S C+P +IR K +L S YFMA A
Sbjct: 202 MNYSLAAKIASSAATLYDSCVHAFESMEPACNPNFIRLASAKKAALEGFSSYFMARAQLE 261
Query: 243 S-------GLHQVQKQ--NYAQGICD-FQYALTWINKLSLDDE----LTEWRGEVQALLE 288
G Q K + AQ + + + + +I+K SL D T + + LL+
Sbjct: 262 KSKQGLAIGYLQQAKSILSSAQKLFNGIKLSTDFIHKPSLSDYPQTISTFIKSSLSHLLK 321
Query: 289 SAERDNDLIYLQASVQNPS--KVKPVMMV----------QADLFDEIEKKDG-NIFKNLL 335
+AE+DND ++ V+ K+ P+ + D F+ +K G ++FK +
Sbjct: 322 TAEKDNDFVFHDLVVKEVELPKISPLQALPPLPLEKLYGSQDGFETAKKIVGDDLFKAFV 381
Query: 336 PIDVLESCNAFNE------RVETYVKEHISNPLESMNKLLISNTPQ---YMDFKSYYISE 386
P V + + ++E R E E + + ++ L + Q + D K+ +I +
Sbjct: 382 PSAVTTASSLYSEETAKVFRAEQAEVERQNTQMATVFASLDLSRLQEITHSDSKTNFIPK 441
Query: 387 Q--EWNSYSDSLQDLEQLRAYVAGELKLSESI------LQKDIQENEQMIREHGLLRWKI 438
+ E S S ++ A KL + I L+ + EN +M + G W +
Sbjct: 442 ELIEARSQLISFNPTFKIHELFAKSTKLKQIIAKIKSDLEVEANENAKMKAKLG-PSWTL 500
Query: 439 PSKDKKIESLLADLTNIRNYIENGMKVDTETASLFKTLDHDLVT-----NVSQPPESS-- 491
+ ++L N + D+ + + + D+ T +S ESS
Sbjct: 501 SDSLEFAAPYQSELNNYLKTLAEASATDSAISQQYALVKDDVETLCNSSKISALLESSIS 560
Query: 492 ------------------------------DPIMKEASLILQGRKNHILAAERKIIENRL 521
+ + ++ R+ + A ++K +++ +
Sbjct: 561 STDNSGQSLLDIPIEQEEQERDMKIQLDLLEELQSRVQKLVPERQTTLQALQQKCLQDDI 620
Query: 522 LPKIVSYYK-KTGSKDFEPVFQEHIRMFD-----------------GDLLQVQKEKAKNK 563
++ K K + D +F+ ++ FD ++ V ++ +N
Sbjct: 621 SESLMQNSKRKDSALDTNQLFELELKKFDPLRNRLHASYRQQQLLLNEMRNVTQKLKQNP 680
Query: 564 EMLTKVTLSSPEQVQISRNDPRTLYLEELKHSSNVLSELKENIISGKQFYQDLITALESK 623
E L K+ + + Q S+N L SS + E + G ++Y+ +E +
Sbjct: 681 EFLRKMEVYNN---QFSKNKE---LCSNLLSSSLTAKAISEGVSKGLEYYK----TVEQR 730
Query: 624 LKEIEDYVNERKLQRTELNDTLLCDTNES 652
L EI + E+ L R + T L + S
Sbjct: 731 LAEINKTLGEQLLLRRKQGATCLSKLSSS 759
>Hs19882237 [R] KOG2220 Predicted signal transduction protein
Length = 695
Score = 72.4 bits (176), Expect = 2e-12
Identities = 60/246 (24%), Positives = 112/246 (45%), Gaps = 17/246 (6%)
Query: 10 KRALQINLKDAFTVVINNTFYQTAASVEADLTQLDKYRDVLFHLDVCQADLNMLKQYYMA 69
K +++ +I+ F + AS EA++ +L+ R + ++ L +L YY
Sbjct: 115 KETKELDWSTPLKELISVHFGEDGASYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQ 174
Query: 70 LKAIAVKLPDDQ----VEFTWFNTL-GLKSSGMTRNSLRFETFNVLYNIGAMYSSLAVEQ 124
L + + + F W+++L G+ + + +L FE +VL+NIGA+++ + Q
Sbjct: 175 LCFLDARFLTPARSLGLFFHWYDSLTGVPAQ---QRALAFEKGSVLFNIGALHTQIGARQ 231
Query: 125 RLESTEGLKESCRLFKLSAGCFKFIYEHEVSNNFKFFDEYTLNALVSMMLAQAQQMVWK- 183
TEG + + F+ +AG F + E+ +L AL +M+AQAQ+ V++
Sbjct: 232 DRSCTEGARRAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEG 291
Query: 184 -----KACFDDIERHSILSRLALQVALFYQTASKNSNCSP---YIRTDWVKSLTSKSHYF 235
D L++ A QVA Y+ + P Y+ W + K+ YF
Sbjct: 292 LSPPASMAPQDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDYVPVSWTALVHVKAEYF 351
Query: 236 MAIAYY 241
++A+Y
Sbjct: 352 RSLAHY 357
>7294357_1 [R] KOG2220 Predicted signal transduction protein
Length = 1461
Score = 65.9 bits (159), Expect = 2e-10
Identities = 70/327 (21%), Positives = 144/327 (43%), Gaps = 33/327 (10%)
Query: 62 MLKQYYMALKAIAVKLPD--DQVEFTWFNTLGLKSSGMTR-NSLRFETFNVLYNIGAMYS 118
++K+YY L A+ + P D+ FT F L S + LRFE VL+NI A+++
Sbjct: 65 VMKRYYCQLHALQNRFPQLADRGIFT-FKWKDLYHSAVHEVTDLRFERAAVLFNIAALHT 123
Query: 119 SLAVEQRLESTEGLKESCRLFKLSAGCFKFIYEH--EVSNNFKFFDEYTLNALVSMMLAQ 176
+G+K +C F+ +A + + E V+ F L + AQ
Sbjct: 124 QSGASVTRGDVDGMKMACTHFQAAAWAYGELRERYANVNGGGDFMTPELLVFQQQVCFAQ 183
Query: 177 AQQMVWKKACFDDIERHSILSRLALQVALFY-------QTASKNSNCSPYIRTD----WV 225
AQ+ + +K+ D+ + H I++++ Q+ ++Y T + + I + W
Sbjct: 184 AQECILEKSLIDNRKPH-IVAKVTAQIVVYYGAALAALLTGGDDGPVAQVIDSSVYKLWK 242
Query: 226 KSLTSKSHYFMAIAYYRSGLHQVQKQNYAQGICDFQYALTWI-----------NKLSLDD 274
K + K +Y I Y G H +K+ + + +Q + + ++ +++
Sbjct: 243 KYVRFKINYLTCILYLYQGQHSEEKRQMGERVTLYQASWDKLEEARKESKGLPDQREINE 302
Query: 275 ELTEWRGEVQALLESAERDNDLIYLQA--SVQNPSKVKPVMMVQADLF--DEIEKKDGNI 330
L+ V+A ++A+ +N+ IY +A + + V+ +V F + E +I
Sbjct: 303 SLSFTADVVEAKRKNAKNENEFIYHEAVPELSTIAAVQGANLVNGIGFQVSDEEHAGPDI 362
Query: 331 FKNLLPIDVLESCNAFNERVETYVKEH 357
F L+P+ E+ + ++E ++++
Sbjct: 363 FARLVPMKAHEASSLYSEEKAKLLRKY 389
>Hs14916439 [R] KOG2220 Predicted signal transduction protein
Length = 685
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/209 (24%), Positives = 98/209 (46%), Gaps = 19/209 (9%)
Query: 57 QADLNMLKQYYMALKAIAVKL--PDDQVE--FTWFNTLGLKSSGMTRNSLRFETFNVLYN 112
+A + +L Y++ L + + P Q+ FTW+++L + E +VL+N
Sbjct: 165 EAGVELLMTYFIQLDFVESRFFPPTRQMGLLFTWYDSLTGVPEPAEPGA---EKASVLFN 221
Query: 113 IGAMYSSLAVEQRLESTEGLKESCRLFKLSAGCFKFIYEHEVSNNFKF-FDEYTLNALVS 171
GA+Y+ + ++ GL+ + F+ +AG ++ H ++ + L+ LV
Sbjct: 222 TGALYTQIGTRCDRQTEAGLESAIDAFQRAAGVLNYLKVHTFTHTPSYDMSPAMLSVLVK 281
Query: 172 MMLAQAQQMVWKKACFDDIERHSIL----SRLALQVALFYQTASKNSNCSPY---IRTDW 224
MMLAQAQ+ V++K I + ++ A +V YQ + + +P I W
Sbjct: 282 MMLAQAQECVFEKISLPGIRNEFFMLVKVAQEAAKVGEVYQQLHQAMSQAPVKENIPYLW 341
Query: 225 VKSLTSKSHYFMAIAYYRSGL----HQVQ 249
K+H++ A+A+Y + + HQV+
Sbjct: 342 ASLACVKAHHYAALAHYFTAILLIDHQVK 370
>7293132 [R] KOG2220 Predicted signal transduction protein
Length = 648
Score = 55.5 bits (132), Expect = 3e-07
Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 17/194 (8%)
Query: 62 MLKQYYMALKAIAVKL-PDDQ---VEFTWFNTL-GLKSSGMTRNSLRFETFNVLYNIGAM 116
+L +YY L + + P D+ V F W+++L G+ S T + FE L+N+G +
Sbjct: 110 LLFRYYNTLYYVERRFFPPDRNLGVYFEWYDSLTGVPSCQRT---IAFEKACTLFNLGGI 166
Query: 117 YSSLAVEQRLESTEGLKESCRLFKLSAGCFKFIYEHEVSNNFKFFDEYTLNALVSMMLAQ 176
Y+ + + GL + F +AG F+ IY+ + L+ LVS+ML+Q
Sbjct: 167 YTQIGARHDRTTERGLDLAVDSFLRAAGVFRHIYDTFTNAPSMDLKPQVLDVLVSLMLSQ 226
Query: 177 AQQMVWKK------ACFDDIERHSILSRLALQVALFYQTASKN---SNCSPYIRTDWVKS 227
A++ +++K A D + L+ A Q++ Y KN ++ Y+ W
Sbjct: 227 ARECLFEKLQLQIEAMSHDCQAFRDLAGEAAQISHEYNEMHKNIQANDTHTYLPECWAGL 286
Query: 228 LTSKSHYFMAIAYY 241
+ K+ + A A++
Sbjct: 287 VPVKAELYKAFAHF 300
>CE24434_1 [R] KOG2220 Predicted signal transduction protein
Length = 670
Score = 50.4 bits (119), Expect = 8e-06
Identities = 45/163 (27%), Positives = 88/163 (53%), Gaps = 16/163 (9%)
Query: 63 LKQYYMALKAIAVKLP---DDQVE--FTWFNTL-GLKS--SGMTRNSLRFETFNVLYNIG 114
LK+YY L + + P +Q+E F W + L ++S S +T + FE +V++NIG
Sbjct: 50 LKRYYGQLCMMQKRFPMGAGEQLETPFAWHDGLIDIRSAQSEVTICDIEFEKASVMFNIG 109
Query: 115 AMYSSLAVEQRLESTEGLKESCRLFKLSAGCFKFIYEHEVSNNFKFFDEYTLNALV---- 170
A ++ A EQ ++ + +K + F+ +A F+ + + N+ F+ L+A V
Sbjct: 110 ACHAQYAAEQTRDTQDCIKAAFMHFQYAAYAFEQL--NSFRNSDIFYPSVDLDANVISFY 167
Query: 171 -SMMLAQAQQMVWKKACFDDIERHSILSRLALQVALFYQTASK 212
+M+AQAQ+ + +K+ D+ ++++L+L + Y +A+K
Sbjct: 168 YKVMIAQAQECLVQKSLLDN-RSAIVIAKLSLWLQEAYDSAAK 209
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.132 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,572,355
Number of Sequences: 60738
Number of extensions: 1522016
Number of successful extensions: 5588
Number of sequences better than 1.0e-05: 15
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 5549
Number of HSP's gapped (non-prelim): 21
length of query: 652
length of database: 30,389,216
effective HSP length: 113
effective length of query: 539
effective length of database: 23,525,822
effective search space: 12680418058
effective search space used: 12680418058
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)