ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII1916 good C KOG2450 Energy production and conversion Aldehyde dehydrogenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII1916 684506 682965 -514
(514 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YER073w [C] KOG2450 Aldehyde dehydrogenase 813 0.0
YOR374w [C] KOG2450 Aldehyde dehydrogenase 707 0.0
SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase 524 e-148
YPL061w [C] KOG2450 Aldehyde dehydrogenase 523 e-148
CE29393 [C] KOG2450 Aldehyde dehydrogenase 488 e-138
CE23852 [C] KOG2450 Aldehyde dehydrogenase 476 e-134
SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase 473 e-133
7297513 [C] KOG2450 Aldehyde dehydrogenase 471 e-133
Hs11436533 [C] KOG2450 Aldehyde dehydrogenase 469 e-132
Hs19923115 [C] KOG2450 Aldehyde dehydrogenase 466 e-131
Hs4502033 [C] KOG2450 Aldehyde dehydrogenase 462 e-130
At3g48000 [C] KOG2450 Aldehyde dehydrogenase 462 e-130
Hs10835045 [C] KOG2450 Aldehyde dehydrogenase 458 e-129
7301524 [C] KOG2450 Aldehyde dehydrogenase 457 e-128
HsM4502031 [C] KOG2450 Aldehyde dehydrogenase 455 e-128
Hs21361176 [C] KOG2450 Aldehyde dehydrogenase 455 e-128
At1g23800 [C] KOG2450 Aldehyde dehydrogenase 449 e-126
Hs4502041 [C] KOG2450 Aldehyde dehydrogenase 435 e-122
Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 429 e-120
HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 426 e-119
YMR170c [C] KOG2450 Aldehyde dehydrogenase 422 e-118
YMR169c [C] KOG2450 Aldehyde dehydrogenase 412 e-115
Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 407 e-113
CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 344 2e-94
Hs4502047 [C] KOG2450 Aldehyde dehydrogenase 341 2e-93
At3g48170 [C] KOG2450 Aldehyde dehydrogenase 336 6e-92
At1g79440 [C] KOG2451 Aldehyde dehydrogenase 324 2e-88
CE07233 [C] KOG2450 Aldehyde dehydrogenase 320 2e-87
Hs12007648 [C] KOG2450 Aldehyde dehydrogenase 315 1e-85
At1g74920 [C] KOG2450 Aldehyde dehydrogenase 305 1e-82
7301355 [C] KOG2451 Aldehyde dehydrogenase 304 2e-82
CE24573 [C] KOG2450 Aldehyde dehydrogenase 302 7e-82
SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase 300 3e-81
7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 290 3e-78
Hs4507229 [C] KOG2451 Aldehyde dehydrogenase 286 7e-77
SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase 284 3e-76
CE06980 [C] KOG2450 Aldehyde dehydrogenase 280 3e-75
SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase 278 2e-74
YBR006w [C] KOG2451 Aldehyde dehydrogenase 277 2e-74
CE10542 [C] KOG2451 Aldehyde dehydrogenase 261 2e-69
Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 210 5e-54
7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 208 1e-53
CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 206 7e-53
At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 202 1e-51
At2g24270 [C] KOG2450 Aldehyde dehydrogenase 193 6e-49
At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase 190 4e-48
CE01232 [C] KOG2453 Aldehyde dehydrogenase 184 2e-46
At1g54100 [C] KOG2453 Aldehyde dehydrogenase 180 5e-45
SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase 172 1e-42
Hs4557343 [C] KOG2453 Aldehyde dehydrogenase 172 1e-42
YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G 170 4e-42
7293810 [C] KOG2453 Aldehyde dehydrogenase 169 1e-41
CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 157 3e-38
CE13415 [C] KOG2456 Aldehyde dehydrogenase 154 2e-37
CE27441 [C] KOG2456 Aldehyde dehydrogenase 154 3e-37
Hs20546780 [C] KOG2450 Aldehyde dehydrogenase 144 3e-34
HsM4502035 [C] KOG2456 Aldehyde dehydrogenase 140 6e-33
Hs21359829 [C] KOG2456 Aldehyde dehydrogenase 140 6e-33
SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrog... 139 1e-32
Hs4557303 [C] KOG2456 Aldehyde dehydrogenase 139 1e-32
Hs18603595 [C] KOG2456 Aldehyde dehydrogenase 139 1e-32
YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 137 4e-32
Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 137 4e-32
At1g44170 [C] KOG2456 Aldehyde dehydrogenase 136 7e-32
7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 135 1e-31
Hs4502043 [C] KOG2456 Aldehyde dehydrogenase 132 2e-30
YMR110c [C] KOG2456 Aldehyde dehydrogenase 123 6e-28
Hs4502045 [C] KOG2456 Aldehyde dehydrogenase 123 6e-28
7304212 [C] KOG2456 Aldehyde dehydrogenase 106 7e-23
7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 102 1e-21
At4g36250 [C] KOG2456 Aldehyde dehydrogenase 97 4e-20
7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 83 9e-16
Hs20481620 [C] KOG2456 Aldehyde dehydrogenase 78 3e-14
At4g34240 [C] KOG2456 Aldehyde dehydrogenase 68 3e-11
Hs20479244 [C] KOG2450 Aldehyde dehydrogenase 66 1e-10
At5g62530 [C] KOG2451 Aldehyde dehydrogenase 59 2e-08
>YER073w [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 813 bits (2100), Expect = 0.0
Identities = 389/518 (75%), Positives = 441/518 (85%), Gaps = 6/518 (1%)
Query: 1 MLGRTQVTT------LRRFIRLYSQLPLKVPVQLPNGITYEQPTGLFINGEFVPSRQHKT 54
ML RT+ R +RLYSQ PL+VP+ LPNG TYEQPTGLFINGEFV S+Q KT
Sbjct: 1 MLSRTRAAAPNSRIFTRSLLRLYSQAPLRVPITLPNGFTYEQPTGLFINGEFVASKQKKT 60
Query: 55 FEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAEPEDRAKCLLKLADLIDQH 114
F+V+NPSNEE+IT +Y+A E F WS EPE RAK L LADL+++H
Sbjct: 61 FDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAFETKWSIVEPEVRAKALFNLADLVEKH 120
Query: 115 AETLASIESLDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGKVIDTGADHFSYTKREPL 174
ETLA+IES+DNGKSLFC+RGDVALV+KYLRSC GWADKIYG VIDTG +HF+Y+ +EPL
Sbjct: 121 QETLAAIESMDNGKSLFCARGDVALVSKYLRSCGGWADKIYGNVIDTGKNHFTYSIKEPL 180
Query: 175 GVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVN 234
GVCGQIIPWNFPLLMWSWK+GPALATGNTVVLKPAE TPLSAL+A QL QEAG+P GVVN
Sbjct: 181 GVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAETTPLSALFASQLCQEAGIPAGVVN 240
Query: 235 IIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIKKVTLELGGKSPNIVFGD 294
I+PG G++VGER+ HPD+KK+AFTGSTATGRHIMK AD++KKVTLELGGKSPNIVF D
Sbjct: 241 ILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMKVAADTVKKVTLELGGKSPNIVFAD 300
Query: 295 ADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQYAESLKVGNPFEENVF 354
ADLDKAVKNIAFGIFYNSGEVCCAGSRIY+QDTVYEEVL+K K Y ESLKVG+PF+E VF
Sbjct: 301 ADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVYEEVLQKLKDYTESLKVGDPFDEEVF 360
Query: 355 QGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGYFIKPTIFADVKEDMQIVKEEI 414
QGAQTS Q+ KIL YVDV SEGAR++TGG R G+KGYF+KPT+FADVK DM+IVKEE+
Sbjct: 361 QGAQTSDKQLHKILDYVDVAKSEGARLVTGGARHGSKGYFVKPTVFADVKGDMRIVKEEV 420
Query: 415 FGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFH 474
FGP+VTVSKF+TVDEV+A ANDS+YGLAAGIHT D+NKA+DVS RVKAGTVWINTYNNFH
Sbjct: 421 FGPIVTVSKFSTVDEVIAMANDSQYGLAAGIHTNDINKAVDVSKRVKAGTVWINTYNNFH 480
Query: 475 QNVPFGGFGQSGIGREMGAEALDNYTQTKAVRMAIDHP 512
QNVPFGGFGQSGIGREMG AL NYTQTK+VR+AID P
Sbjct: 481 QNVPFGGFGQSGIGREMGEAALSNYTQTKSVRIAIDKP 518
>YOR374w [C] KOG2450 Aldehyde dehydrogenase
Length = 519
Score = 707 bits (1824), Expect = 0.0
Identities = 336/509 (66%), Positives = 416/509 (81%), Gaps = 2/509 (0%)
Query: 4 RTQVTTLRRF-IRLYSQLPLKVPVQLPNGITYEQPTGLFINGEFVPSRQHKTFEVLNPSN 62
+T +++ R +R +S LP+ VP++LPNG+ YEQPTGLFIN +FVPS+Q+KTFEV+NPS
Sbjct: 10 KTSASSIGRLQLRYFSHLPMTVPIKLPNGLEYEQPTGLFINNKFVPSKQNKTFEVINPST 69
Query: 63 EEEITHIYEAREXXXXXXXXXXXXXFNNG-WSTAEPEDRAKCLLKLADLIDQHAETLASI 121
EEEI HIYE RE F+NG W+ +P DR K L +LA+LI+Q + +ASI
Sbjct: 70 EEEICHIYEGREDDVEEAVQAADRAFSNGSWNGIDPIDRGKALYRLAELIEQDKDVIASI 129
Query: 122 ESLDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGKVIDTGADHFSYTKREPLGVCGQII 181
E+LDNGK++ SRGDV LV YL+S AG+ADKI G++IDTG HFSYTKR+PLGVCGQII
Sbjct: 130 ETLDNGKAISSSRGDVDLVINYLKSSAGFADKIDGRMIDTGRTHFSYTKRQPLGVCGQII 189
Query: 182 PWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGK 241
PWNFPLLMW+WK+ PAL TGNTVVLK AE+TPLSALY + + +AG+P GV+NI+ GFGK
Sbjct: 190 PWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYIPQAGIPPGVINIVSGFGK 249
Query: 242 IVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIKKVTLELGGKSPNIVFGDADLDKAV 301
IVGE I HP IKKVAFTGSTATGRHI ++ A +KKVTLELGGKSPNIVF DA+L KAV
Sbjct: 250 IVGEAITNHPKIKKVAFTGSTATGRHIYQSAAAGLKKVTLELGGKSPNIVFADAELKKAV 309
Query: 302 KNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQ 361
+NI GI+YNSGEVCCAGSR+YV++++Y++ +E+FK +ES+KVG+PF+E+ FQGAQTSQ
Sbjct: 310 QNIILGIYYNSGEVCCAGSRVYVEESIYDKFIEEFKAASESIKVGDPFDESTFQGAQTSQ 369
Query: 362 MQIDKILSYVDVGTSEGARVITGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTV 421
MQ++KIL YVD+G +EGA +ITGGER+G+KGYFIKPT+F DVKEDM+IVKEEIFGPVVTV
Sbjct: 370 MQLNKILKYVDIGKNEGATLITGGERLGSKGYFIKPTVFGDVKEDMRIVKEEIFGPVVTV 429
Query: 422 SKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGG 481
+KF + DEV+ ANDSEYGLAAGIHT ++N A+ V++RV AGTVWINTYN+FH VPFGG
Sbjct: 430 TKFKSADEVINMANDSEYGLAAGIHTSNINTALKVADRVNAGTVWINTYNDFHHAVPFGG 489
Query: 482 FGQSGIGREMGAEALDNYTQTKAVRMAID 510
F SG+GREM +AL NY Q KAVR +D
Sbjct: 490 FNASGLGREMSVDALQNYLQVKAVRAKLD 518
>SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 524 bits (1350), Expect = e-148
Identities = 259/494 (52%), Positives = 339/494 (68%), Gaps = 5/494 (1%)
Query: 24 VPVQLPNGITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXX 83
V + +P G TY QP GLFIN + V S +V +PS E+ I + +A E
Sbjct: 9 VEITVPTGKTYIQPVGLFINNQHVDSVHGGRVKVYSPSTEKLICEVADADEEDVDIAVKV 68
Query: 84 XXXXFNNG--WSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVA 141
F W R +CL +LAD I+Q+ E LASIE+LDNGKS+ +RGDV A
Sbjct: 69 ARAAFQTDAPWRKFSSAQRGRCLSRLADCIEQNLEYLASIETLDNGKSITLARGDVQAAA 128
Query: 142 KYLRSCAGWADKIYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATG 201
R GWADK YG+ I+T F+YT+ EP+GVCGQIIPWNFP LM +WK+ PA+A G
Sbjct: 129 DCFRYYGGWADKDYGQTIETDIKRFAYTRHEPIGVCGQIIPWNFPFLMCAWKIAPAVACG 188
Query: 202 NTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGS 261
NT++LK AE TPLSAL + V E G P GV+N++ G G+ G I +H DI KVAFTGS
Sbjct: 189 NTIILKTAELTPLSALCLTKFVPECGFPPGVINVLSGDGRRCGNAISSHMDIDKVAFTGS 248
Query: 262 TATGRHIMKTCADS-IKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGS 320
T GR +M+ A S +KKVTLELGGKSPNIVF DADLD A +GIFYNSG+VCCAGS
Sbjct: 249 TGVGRMVMRAAASSNLKKVTLELGGKSPNIVFNDADLDSAAVWTNYGIFYNSGQVCCAGS 308
Query: 321 RIYVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGAR 380
R+YVQ+ VY+E +++ A++LKVG+PF E+ FQGAQ S+ Q ++I+SY++ G + GA+
Sbjct: 309 RVYVQEDVYDEFIKRMVAKAKTLKVGDPFAEDTFQGAQVSKQQYERIVSYIESGIAHGAK 368
Query: 381 VITGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYG 440
+ GG+R GN GYF++PTI ++V EDM + KEEIFGPV+ V KF T++E + + N+S YG
Sbjct: 369 LEIGGKRHGNLGYFVEPTILSNVTEDMAVGKEEIFGPVLAVIKFKTIEEAIRRGNNSTYG 428
Query: 441 LAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYT 500
LAAG+HT ++ AI VSN ++AGTVW+N YN H +PFGG+ +SGIGRE+G+ L NYT
Sbjct: 429 LAAGVHTNNITNAIKVSNALEAGTVWVNCYNLLHHQIPFGGYKESGIGRELGSYGLTNYT 488
Query: 501 QTKAV--RMAIDHP 512
QTKAV + +D P
Sbjct: 489 QTKAVHINLGMDSP 502
>YPL061w [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 523 bits (1346), Expect = e-148
Identities = 249/489 (50%), Positives = 350/489 (70%), Gaps = 3/489 (0%)
Query: 24 VPVQLPNGITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXX 83
V + LPNG+TYEQPTGLFIN +F+ ++ KT+ V +PS E + + A
Sbjct: 12 VKITLPNGLTYEQPTGLFINNKFMKAQDGKTYPVEDPSTENTVCEVSSATTEDVEYAIEC 71
Query: 84 XXXXFNNG-WSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAK 142
F++ W+T +P +R + L KLAD ++ + ++SIE+LDNGK+L +RGDV +
Sbjct: 72 ADRAFHDTEWATQDPRERGRLLSKLADELESQIDLVSSIEALDNGKTLALARGDVTIAIN 131
Query: 143 YLRSCAGWADKIYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGN 202
LR A +ADK+ G+ I+TG + ++T EP+GVCGQIIPWNFP++M +WK+ PALA GN
Sbjct: 132 CLRDAAAYADKVNGRTINTGDGYMNFTTLEPIGVCGQIIPWNFPIMMLAWKIAPALAMGN 191
Query: 203 TVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGST 262
+LKPA TPL+ALY L ++ G+P GVVNI+PG G+ VG + P I+K+AFTGST
Sbjct: 192 VCILKPAAVTPLNALYFASLCKKVGIPAGVVNIVPGPGRTVGAALTNDPRIRKLAFTGST 251
Query: 263 ATGRHIMKTCADS-IKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSR 321
G+ + ++S +KK+TLELGGKS ++VF DA++ K + N+ GIF N+G++C +GSR
Sbjct: 252 EVGKSVAVDSSESNLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSSGSR 311
Query: 322 IYVQDTVYEEVLEKFKQYAES-LKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGAR 380
IYVQ+ +Y+E+L FK Y E+ +KVGNPF++ FQGA T++ Q D I++Y+D+G EGA+
Sbjct: 312 IYVQEGIYDELLAAFKAYLETEIKVGNPFDKANFQGAITNRQQFDTIMNYIDIGKKEGAK 371
Query: 381 VITGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYG 440
++TGGE++G+KGYFI+PT+F DV EDM+IVKEEIFGPVVTV+KF T++E V AN SE+G
Sbjct: 372 ILTGGEKVGDKGYFIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSEFG 431
Query: 441 LAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYT 500
L +GI T+ ++ + V+ +KAGTVWINTYN+F VPFGG QSG GREMG E YT
Sbjct: 432 LGSGIETESLSTGLKVAKMLKAGTVWINTYNDFDSRVPFGGVKQSGYGREMGEEVYHAYT 491
Query: 501 QTKAVRMAI 509
+ KAVR+ +
Sbjct: 492 EVKAVRIKL 500
>CE29393 [C] KOG2450 Aldehyde dehydrogenase
Length = 510
Score = 488 bits (1256), Expect = e-138
Identities = 241/492 (48%), Positives = 334/492 (66%), Gaps = 6/492 (1%)
Query: 28 LPNGITYEQP--TGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXX 85
+P G++ +P TG+FIN EFVP++ KTFE +NP+N + + + E +
Sbjct: 18 VPPGLSNMKPQYTGIFINNEFVPAKSGKTFETINPANGKVLAQVAEGDKTDVNIAVKAAQ 77
Query: 86 XXFNNG--WSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCS-RGDVALVAK 142
F G W + R L +LADL+++ LAS+ESLDNGK + D+ L K
Sbjct: 78 NAFRIGSEWRRMDASQRGVLLNRLADLMERDRVILASLESLDNGKPYAVAYNADLPLSIK 137
Query: 143 YLRSCAGWADKIYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGN 202
LR ADK +GK I D+F+YT+ EP+GVCGQIIPWNFPLLM +WK+GPALA GN
Sbjct: 138 TLRLLRRMADKNHGKTIPIEGDYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALAMGN 197
Query: 203 TVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGST 262
TVV+K AE TPLSAL+ L +EAG P GVVNIIPG+G G+ I +H D+ KVAFTGST
Sbjct: 198 TVVMKVAEQTPLSALHVAALTKEAGFPDGVVNIIPGYGHTAGQAISSHMDVDKVAFTGST 257
Query: 263 ATGRHIMKTCADS-IKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSR 321
GR +MK A+S +KKVTLELGGKSPNI+F DADL+ +V G+F+N G+ CCAGSR
Sbjct: 258 EVGRLVMKAAAESNVKKVTLELGGKSPNIIFADADLNDSVHQANHGLFFNQGQCCCAGSR 317
Query: 322 IYVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARV 381
+V+ +Y++ + + K+ AE +G+PF+ QG Q Q++ IL Y+ G +GA++
Sbjct: 318 TFVEGKIYDDFVARSKELAEKAVIGDPFDLKTTQGPQVDGKQVETILKYIAAGKKDGAQL 377
Query: 382 ITGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGL 441
+TGG + G++G+F+KPTIFA+VK+ M I +EEIFGPV+T+ +F T++E+V KAN++ YGL
Sbjct: 378 VTGGAKHGDQGHFVKPTIFANVKDQMTIAQEEIFGPVMTIIRFDTMEELVEKANNTIYGL 437
Query: 442 AAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQ 501
AAG+ TKD++KA+ ++N +AG+VW+N Y+ F PFGGF QSGIGRE+G L+ YT+
Sbjct: 438 AAGVMTKDIDKALHIANATRAGSVWVNCYDVFDAAAPFGGFKQSGIGRELGEYGLEAYTE 497
Query: 502 TKAVRMAIDHPN 513
K V + + N
Sbjct: 498 VKTVTIKVPQKN 509
>CE23852 [C] KOG2450 Aldehyde dehydrogenase
Length = 537
Score = 476 bits (1224), Expect = e-134
Identities = 237/478 (49%), Positives = 325/478 (67%), Gaps = 4/478 (0%)
Query: 40 LFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNG--WSTAEP 97
LFIN EFV ++ KTFE +NP+N + + + E F G W +
Sbjct: 59 LFINNEFVDAKSGKTFEFVNPANGKLLAKVAEGNRDDVDIAVEAAKKAFKIGSEWRRMDA 118
Query: 98 EDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRG-DVALVAKYLRSCAGWADKIYG 156
R L +LADL+++ LAS+ESLDNGK + D+ + K R AG+ADK +G
Sbjct: 119 SHRGVLLNRLADLMERDRVILASLESLDNGKPYKEAYNIDLPISIKTFRYYAGYADKNHG 178
Query: 157 KVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSA 216
K I G D+F+YT+ EP+GVCGQIIPWNFPLLM +WK+ PALA GNTVV+K A TPLSA
Sbjct: 179 KTIPVGGDYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLAPALAMGNTVVMKVAVKTPLSA 238
Query: 217 LYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADS- 275
L+ L++EA P+GVVNIIPG G GE I +H D+ KVAFTGST G+ IMK A+S
Sbjct: 239 LHVASLIKEAQFPEGVVNIIPGRGTDAGEAIASHMDVDKVAFTGSTEVGKTIMKAAAESN 298
Query: 276 IKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEK 335
+KKVTLELGGKSPNIVF DADL++AV+ +F+N G+ C AGSR +V+ +Y+E + K
Sbjct: 299 VKKVTLELGGKSPNIVFADADLEEAVRQSHHALFFNQGQCCSAGSRTFVEGKIYDEFVAK 358
Query: 336 FKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGYFI 395
K+ E +G+PF+EN QG Q + Q++ I+ Y++ G EGA+++TGG + G++GYF+
Sbjct: 359 AKELVEKTVIGDPFDENTTQGPQIDESQVETIMKYIESGKKEGAQLVTGGVKHGDQGYFV 418
Query: 396 KPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAID 455
KPTIFA+V + M+I +EEIFGPV+ V +F +++E++ KAN++ YGLAAG+ T D+NKA+
Sbjct: 419 KPTIFANVNDQMKIAQEEIFGPVMIVIRFDSMEELIEKANNTIYGLAAGVVTNDLNKALQ 478
Query: 456 VSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAVRMAIDHPN 513
V+N ++AG+VW+N Y+ F PFGGF QSGIGRE+G L YT+ K V + + N
Sbjct: 479 VANTIRAGSVWVNCYDVFDPAAPFGGFKQSGIGRELGEYGLAAYTEVKTVTIKVPQKN 536
>SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 473 bits (1216), Expect = e-133
Identities = 244/489 (49%), Positives = 327/489 (65%), Gaps = 6/489 (1%)
Query: 22 LKVPVQLPNGITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXX 81
L V + PNG + +QP GL+INGE+ S + T+E ++PS EE I +Y A E
Sbjct: 5 LFVSINFPNGKSVKQPIGLYINGEWHKSAE--TWETVDPSIEEVIAKVYLAGEKEIDYAV 62
Query: 82 XXXXXXFNNGWSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCS-RGDVALV 140
F W ++ + L+KLA+L ++HA+TLA+IE++D+GK L + RGDV
Sbjct: 63 KSAKEAFKT-WKKVPGSEKGELLMKLAELTEKHADTLAAIEAMDSGKPLVSNARGDVDGT 121
Query: 141 AKYLRSCAGWADKIYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALAT 200
LR CAGWADKIYG+VI TG + +Y KR P+GVCGQI+PWN+PL M WK+ PALA
Sbjct: 122 IALLRYCAGWADKIYGQVIPTGPEKLAYAKRTPIGVCGQIVPWNYPLNMAGWKIAPALAA 181
Query: 201 GNTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTG 260
GN +++K AE TPLS LY LV+EAG PKGVVNII G G + G + HP I K+AFTG
Sbjct: 182 GNCIIIKSAETTPLSLLYFATLVEEAGFPKGVVNIISGLGTVAGSYMAKHPGIDKIAFTG 241
Query: 261 STATGRHIMKTCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGS 320
ST G + + A ++K VTLE GGKSP +VF DADLD+AVK A GI YNSG++C + S
Sbjct: 242 STKVGVIVQQLAASNLKAVTLECGGKSPFLVFEDADLDQAVKWAALGIMYNSGQICTSNS 301
Query: 321 RIYVQDTVYEEVLEKFKQYA-ESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGA 379
RIYVQD+VY++ +E FK++ + VG PF++N G ++ Q ++I +Y++ G EGA
Sbjct: 302 RIYVQDSVYDKFIELFKKHVIQDYIVGMPFDDNTVVGPVVNKTQYNRIKNYIEQGKKEGA 361
Query: 380 RVITGGERIGNK-GYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSE 438
+++ G E + K GYFI PTIFAD E+M IVKEEIFGPVV +SKF T DE + KAN++
Sbjct: 362 KLVLGDEPLPLKQGYFISPTIFADCSENMTIVKEEIFGPVVAISKFKTEDEAIEKANNTT 421
Query: 439 YGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDN 498
YGLAA TKD+ +A VS+ ++AG V+IN+ N PFGG SGIG E+G+ ++
Sbjct: 422 YGLAAMCFTKDLERAHRVSDELEAGMVFINSTENSDIQAPFGGIKMSGIGNELGSNGIEM 481
Query: 499 YTQTKAVRM 507
YTQ KAV +
Sbjct: 482 YTQIKAVHI 490
>7297513 [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 471 bits (1213), Expect = e-133
Identities = 247/515 (47%), Positives = 334/515 (63%), Gaps = 12/515 (2%)
Query: 4 RTQVTTLRRFIRLYSQLPLKVPVQLPNGITYEQPTGLFINGEFVPSRQHKTFEVLNPSNE 63
R+Q + YS LP P P+ I Y TG+FIN E+ S+ K FE +NP+
Sbjct: 12 RSQAKNFAAAVANYSSLPQ--PQTTPD-ILY---TGVFINNEWHKSKSGKIFETINPTTA 65
Query: 64 EEITHIYEAREXXXXXXXXXXXXXFNNG--WSTAEPEDRAKCLLKLADLIDQHAETLASI 121
E I I A + F G W + +R + L +LADL+++ LAS+
Sbjct: 66 EVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASL 125
Query: 122 ESLDNGKSLFCSRG-DVALVAKYLRSCAGWADKIYGKVIDTGADHFSYTKREPLGVCGQI 180
E+LDNGK S D+ K LR AGWADK +GK I D F+YT+ EP+GVCGQI
Sbjct: 126 ETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNHGKTIPMDGDFFTYTRHEPVGVCGQI 185
Query: 181 IPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFG 240
IPWNFP+LM +WK+GPALATGNT+VLKPAE T L+ALY QLV+EAG P+GVVN++PGFG
Sbjct: 186 IPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFG 245
Query: 241 KIVGERICTHPDIKKVAFTGSTATGRHIMKTCAD-SIKKVTLELGGKSPNIVFGDADLDK 299
G + H D+ KVAFTGST G+ I + ++K+VTLELGGKSPNI+ D D+D
Sbjct: 246 -TAGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDY 304
Query: 300 AVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQT 359
AV+ FG+F+N G+ CCAGSR +V+D +Y+E +E+ + A+ VGNPF+ N QG Q
Sbjct: 305 AVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGNPFDLNTEQGPQV 364
Query: 360 SQMQIDKILSYVDVGTSEGARVITGGER-IGNKGYFIKPTIFADVKEDMQIVKEEIFGPV 418
++ Q++KIL + G +GA+++ GG R G GYF++PT+FADV++DM I +EEIFGPV
Sbjct: 365 NEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPV 424
Query: 419 VTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVP 478
+ +F +DEV+ +AN+SEYGLAA + TKD++KA + ++AGTVW+NTYN P
Sbjct: 425 QQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAP 484
Query: 479 FGGFGQSGIGREMGAEALDNYTQTKAVRMAIDHPN 513
FGG+ SG GRE G AL NYT+ K+V + + N
Sbjct: 485 FGGYKMSGHGRENGEYALSNYTEVKSVIVKVAQKN 519
>Hs11436533 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 469 bits (1207), Expect = e-132
Identities = 237/478 (49%), Positives = 312/478 (64%), Gaps = 4/478 (0%)
Query: 40 LFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNG--WSTAEP 97
+FIN E+ + KTF +NPS E I + E + F G W +
Sbjct: 39 IFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDA 98
Query: 98 EDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSR-GDVALVAKYLRSCAGWADKIYG 156
R + L +LADLI++ LA++E+LDNGK S D+ +V K LR AGWADK +G
Sbjct: 99 SHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHG 158
Query: 157 KVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSA 216
K I D FSYT+ EP+GVCGQIIPWNFPLLM +WK+GPALATGN VV+K AE TPL+A
Sbjct: 159 KTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTA 218
Query: 217 LYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADS- 275
LY L++EAG P GVVNI+PGFG G I +H D+ KVAFTGST GR I S
Sbjct: 219 LYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSN 278
Query: 276 IKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEK 335
+K+VTLELGGKSPNI+ DAD+D AV+ F +F+N G+ CCAGSR +VQ+ +Y+E +E+
Sbjct: 279 LKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVER 338
Query: 336 FKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGYFI 395
A+S VGNPF+ QG Q + Q KIL Y++ G EGA+++ GG ++GYFI
Sbjct: 339 SVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFI 398
Query: 396 KPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAID 455
+PT+F DV++ M I KEEIFGPV+ + KF T++EVV +AN+S YGLAA + TKD++KA
Sbjct: 399 QPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANY 458
Query: 456 VSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAVRMAIDHPN 513
+S ++AGTVW+N Y+ F PFGG+ SG GRE+G L YT+ K V + + N
Sbjct: 459 LSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKN 516
>Hs19923115 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 466 bits (1200), Expect = e-131
Identities = 242/506 (47%), Positives = 324/506 (63%), Gaps = 8/506 (1%)
Query: 12 RFIRLYSQLPLKVPVQLPNGITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYE 71
R R S L P+ P+ I Y Q LFIN E+ + KTF +NP+ E I H+ E
Sbjct: 15 RTARYSSAAALPSPILNPD-IPYNQ---LFINNEWQDAVSKKTFPTVNPTTGEVIGHVAE 70
Query: 72 AREXXXXXXXXXXXXXFNNG--WSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKS 129
F G W + +R + L LADL+++ LAS+E+LDNGK
Sbjct: 71 GDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNLLADLVERDRVYLASLETLDNGKP 130
Query: 130 LFCSRG-DVALVAKYLRSCAGWADKIYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLL 188
S D+ V K R AGWADK +GK I HF +T+ EP+GVCGQIIPWNFPL+
Sbjct: 131 FQESYALDLDEVIKVYRYFAGWADKWHGKTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLV 190
Query: 189 MWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERIC 248
M WK+ PALATGNTVV+K AE TPLSALY L++EAG P GVVNII G+G G I
Sbjct: 191 MQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIA 250
Query: 249 THPDIKKVAFTGSTATGRHIMKTCADS-IKKVTLELGGKSPNIVFGDADLDKAVKNIAFG 307
H D+ KVAFTGST G I K DS +K+VTLELGGKSP+IV DAD++ AV+
Sbjct: 251 QHMDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEA 310
Query: 308 IFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKI 367
+F+N G+ CCAGSR +V++++Y E LE+ + A+ KVGNPFE + QG Q + Q +++
Sbjct: 311 LFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERV 370
Query: 368 LSYVDVGTSEGARVITGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTV 427
L Y+ +G EGA+++ GGER G +G+FIKPT+F V++DM+I KEEIFGPV + KF +
Sbjct: 371 LGYIQLGQKEGAKLLCGGERFGERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKI 430
Query: 428 DEVVAKANDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGI 487
+EVV +AN++ YGLAA + T+D++KA+ + ++AGTVW+NTYN + PFGGF +SG
Sbjct: 431 EEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGN 490
Query: 488 GREMGAEALDNYTQTKAVRMAIDHPN 513
GRE+G + L YT+ K V + + N
Sbjct: 491 GRELGEDGLKAYTEVKTVTIKVPQKN 516
>Hs4502033 [C] KOG2450 Aldehyde dehydrogenase
Length = 516
Score = 462 bits (1190), Expect = e-130
Identities = 235/478 (49%), Positives = 310/478 (64%), Gaps = 4/478 (0%)
Query: 40 LFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNG--WSTAEP 97
+FIN E+ + KTF +NPS E I + E + F G W +
Sbjct: 38 IFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAREGRPGAFQLGSPWRRMDA 97
Query: 98 EDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSR-GDVALVAKYLRSCAGWADKIYG 156
+ L +LADLI++ LA++E+LDNGK S D+ +V K LR AGWADK +G
Sbjct: 98 SHSGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHG 157
Query: 157 KVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSA 216
K I D FSYT+ EP+GVCGQIIPWNFPLLM +WK+GPALATGN VV+K AE TPL+A
Sbjct: 158 KTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTA 217
Query: 217 LYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADS- 275
LY L++EAG P GVVNI+PGFG G I +H D+ KVAFTGST GR I S
Sbjct: 218 LYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSN 277
Query: 276 IKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEK 335
+K+VTLELGGKSPNI+ DAD+D AV+ F +F+N G+ CCAGSR +VQ+ +Y+E + +
Sbjct: 278 LKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVVR 337
Query: 336 FKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGYFI 395
A+S VGNPF+ QG Q + Q KIL Y++ G EGA+++ GG ++GYFI
Sbjct: 338 SVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFI 397
Query: 396 KPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAID 455
+PT+F DV++ M I KEEIFGPV+ + KF T++EVV +AN+S YGLAA + TKD++KA
Sbjct: 398 QPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANY 457
Query: 456 VSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAVRMAIDHPN 513
+S ++AGTVW+N Y+ F PFGG+ SG GRE+G L YT+ K V + + N
Sbjct: 458 LSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKN 515
>At3g48000 [C] KOG2450 Aldehyde dehydrogenase
Length = 538
Score = 462 bits (1189), Expect = e-130
Identities = 234/478 (48%), Positives = 321/478 (66%), Gaps = 3/478 (0%)
Query: 38 TGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNG-WSTAE 96
T L ING FV S KTF L+P E I H+ E F+ G W
Sbjct: 58 TQLLINGNFVDSASGKTFPTLDPRTGEVIAHVAEGDAEDINRAVKAARTAFDEGPWPKMS 117
Query: 97 PEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCS-RGDVALVAKYLRSCAGWADKIY 155
+R++ LL+ ADL+++H+E LAS+E+ DNGK S ++ + A+ R AGWADKI+
Sbjct: 118 AYERSRVLLRFADLVEKHSEELASLETWDNGKPYQQSLTAEIPMFARLFRYYAGWADKIH 177
Query: 156 GKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLS 215
G I ++ +T EP+GV GQIIPWNFPLLM++WKVGPALA GNT+VLK AE TPL+
Sbjct: 178 GLTIPADGNYQVHTLHEPIGVAGQIIPWNFPLLMFAWKVGPALACGNTIVLKTAEQTPLT 237
Query: 216 ALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADS 275
A YA +L EAG+P GV+NI+ GFG G + +H D+ K+AFTGST TG+ I+ A+S
Sbjct: 238 AFYAGKLFLEAGLPPGVLNIVSGFGATAGAALASHMDVDKLAFTGSTDTGKVILGLAANS 297
Query: 276 -IKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLE 334
+K VTLELGGKSP IVF DAD+DKAV+ F +F+N G+ CCAGSR +V + VY+E +E
Sbjct: 298 NLKPVTLELGGKSPFIVFEDADIDKAVELAHFALFFNQGQCCCAGSRTFVHEKVYDEFVE 357
Query: 335 KFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGYF 394
K K A VG+PF + + QG Q Q +K++ Y+ G A + GG++IG+KGYF
Sbjct: 358 KSKARALKRVVGDPFRKGIEQGPQIDLKQFEKVMKYIKSGIESNATLECGGDQIGDKGYF 417
Query: 395 IKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAI 454
I+PT+F++VK+DM I ++EIFGPV ++ KF+ VDEV+ +AN+++YGLAAG+ TK+++ A
Sbjct: 418 IQPTVFSNVKDDMLIAQDEIFGPVQSILKFSDVDEVIKRANETKYGLAAGVFTKNLDTAN 477
Query: 455 DVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAVRMAIDHP 512
VS +KAGTVW+N ++ F +PFGG+ SG GRE G +L+NY Q KAV A++ P
Sbjct: 478 RVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIYSLNNYLQIKAVVTALNKP 535
>Hs10835045 [C] KOG2450 Aldehyde dehydrogenase
Length = 518
Score = 458 bits (1179), Expect = e-129
Identities = 229/480 (47%), Positives = 318/480 (65%), Gaps = 4/480 (0%)
Query: 38 TGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNG--WSTA 95
T +FIN E+ S + F V NP+ E++ + EA + F+ G W
Sbjct: 38 TKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRM 97
Query: 96 EPEDRAKCLLKLADLIDQHAETLASIESLDNGKS-LFCSRGDVALVAKYLRSCAGWADKI 154
+ +R + L KLADL+++ LA++ESL+ GK L D+ V K R AGWADKI
Sbjct: 98 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI 157
Query: 155 YGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPL 214
+G I D+F++T+ EP+GVCGQIIPWNFPLLM++WK+ PAL GNTVV+KPAE TPL
Sbjct: 158 HGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 217
Query: 215 SALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCAD 274
SALY L++EAG P GV+NI+PG+G G I +H I K+AFTGST G+ I +
Sbjct: 218 SALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGR 277
Query: 275 S-IKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVL 333
S +K+VTLELGGKSPNI+F DADLD AV+ G+F+N G+ C AGSRI+V++++YEE +
Sbjct: 278 SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFV 337
Query: 334 EKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGY 393
+ + A+ VG+PF+ QG Q + Q +KIL + G +EGA++ GG+ +G KG+
Sbjct: 338 RRSVERAKRRIVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGF 397
Query: 394 FIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKA 453
FI+PT+F++V +DM+I KEEIFGPV + +F T+DEV+ +AN+S++GL A + T D+NKA
Sbjct: 398 FIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKA 457
Query: 454 IDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAVRMAIDHPN 513
+ VS+ ++AGTVWIN YN + PFGGF SG GREMG L Y++ K V + I N
Sbjct: 458 LTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKN 517
>7301524 [C] KOG2450 Aldehyde dehydrogenase
Length = 659
Score = 457 bits (1177), Expect = e-128
Identities = 234/507 (46%), Positives = 323/507 (63%), Gaps = 10/507 (1%)
Query: 6 QVTTLRRFIRLYSQLPLKVPVQLPNGITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEE 65
Q T +F+++Y L + P P + T LFIN EFV S KTF NP+ +E
Sbjct: 159 QRRTTSKFLKVYISLNMADPNAKP------KYTKLFINNEFVDSVSGKTFATFNPATSKE 212
Query: 66 ITHIYEAREXXXXXXXXXXXXXFNNG--WSTAEPEDRAKCLLKLADLIDQHAETLASIES 123
I + E + F+ W P R + KL L+D+ LAS+E+
Sbjct: 213 IVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLET 272
Query: 124 LDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGKVIDTGADHFSYTKREPLGVCGQIIPW 183
DNGK + DV L+ AGW DK +G I G S T++EP+GV GQIIPW
Sbjct: 273 QDNGKPYAEALFDVTYSILTLQYYAGWTDKFFGDTIPAGG-FVSMTRKEPVGVVGQIIPW 331
Query: 184 NFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIV 243
N+PLLM +WK GPALA G T+++KPAE TPL+AL+ L +EAG P GV+N++ GFG
Sbjct: 332 NYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTA 391
Query: 244 GERICTHPDIKKVAFTGSTATGRHIMKTCADS-IKKVTLELGGKSPNIVFGDADLDKAVK 302
G I HPDI KVAFTGS GR +M+ A S +K+V+LELGGKSP +VF DAD+D AV+
Sbjct: 392 GAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVE 451
Query: 303 NIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQM 362
+F N G+ CCAGSR YV + +Y+E + K A++ KVGNPFE+NV QG Q
Sbjct: 452 TTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQGPQIDDD 511
Query: 363 QIDKILSYVDVGTSEGARVITGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVS 422
+ K+L Y++ G EGA++ GG+RIGN G+F++PT+F+DVK+DM+I +EEIFGPV ++
Sbjct: 512 MLTKVLGYIESGKKEGAKLQAGGKRIGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIF 571
Query: 423 KFTTVDEVVAKANDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGF 482
KF++++E++ +AN+ +YGLAAG+ T D+NKA+ +N V AG+VWIN Y+ + PFGG+
Sbjct: 572 KFSSLEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDAVLPSTPFGGY 631
Query: 483 GQSGIGREMGAEALDNYTQTKAVRMAI 509
SGIGRE+G + LDNY +TK + M +
Sbjct: 632 KHSGIGRELGKDGLDNYLETKTITMKL 658
>HsM4502031 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 455 bits (1171), Expect = e-128
Identities = 231/483 (47%), Positives = 317/483 (64%), Gaps = 6/483 (1%)
Query: 36 QPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNG--WS 93
Q T +FIN E+ S K F V NP+ EEE+ + E + F G W
Sbjct: 19 QYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWR 78
Query: 94 TAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSR--GDVALVAKYLRSCAGWA 151
T + +R + L KLADLI++ LA++ES++ GK L+ + D+A K LR CAGWA
Sbjct: 79 TMDASERGRLLYKLADLIERDRLLLATMESMNGGK-LYSNAYLSDLAGCIKTLRYCAGWA 137
Query: 152 DKIYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEA 211
DKI G+ I + F+YT+ EP+GVCGQIIPWNFPL+M WK+GPAL+ GNTVV+KPAE
Sbjct: 138 DKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQ 197
Query: 212 TPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKT 271
TPL+AL+ L++EAG P GVVNI+PG+G G I +H DI KVAFTGST G+ I +
Sbjct: 198 TPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEA 257
Query: 272 CADS-IKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYE 330
S +K+VTLELGGKSP IV DADLD AV+ G+FY+ G+ C A SRI+V++++Y+
Sbjct: 258 AGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYD 317
Query: 331 EVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGN 390
E + + + A+ +GNP V QG Q + Q DKIL ++ G EGA++ GG GN
Sbjct: 318 EFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGN 377
Query: 391 KGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDV 450
KGYF++PT+F++V ++M+I KEEIFGPV + KF ++D+V+ +AN++ YGL+AG+ TKD+
Sbjct: 378 KGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDI 437
Query: 451 NKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAVRMAID 510
+KAI +S+ ++AGTVW+N Y PFGGF SG GRE+G YT+ K V + I
Sbjct: 438 DKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKIS 497
Query: 511 HPN 513
N
Sbjct: 498 QKN 500
>Hs21361176 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 455 bits (1171), Expect = e-128
Identities = 231/483 (47%), Positives = 317/483 (64%), Gaps = 6/483 (1%)
Query: 36 QPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNG--WS 93
Q T +FIN E+ S K F V NP+ EEE+ + E + F G W
Sbjct: 19 QYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWR 78
Query: 94 TAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSR--GDVALVAKYLRSCAGWA 151
T + +R + L KLADLI++ LA++ES++ GK L+ + D+A K LR CAGWA
Sbjct: 79 TMDASERGRLLYKLADLIERDRLLLATMESMNGGK-LYSNAYLNDLAGCIKTLRYCAGWA 137
Query: 152 DKIYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEA 211
DKI G+ I + F+YT+ EP+GVCGQIIPWNFPL+M WK+GPAL+ GNTVV+KPAE
Sbjct: 138 DKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQ 197
Query: 212 TPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKT 271
TPL+AL+ L++EAG P GVVNI+PG+G G I +H DI KVAFTGST G+ I +
Sbjct: 198 TPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEA 257
Query: 272 CADS-IKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYE 330
S +K+VTLELGGKSP IV DADLD AV+ G+FY+ G+ C A SRI+V++++Y+
Sbjct: 258 AGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYD 317
Query: 331 EVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGN 390
E + + + A+ +GNP V QG Q + Q DKIL ++ G EGA++ GG GN
Sbjct: 318 EFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGN 377
Query: 391 KGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDV 450
KGYF++PT+F++V ++M+I KEEIFGPV + KF ++D+V+ +AN++ YGL+AG+ TKD+
Sbjct: 378 KGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDI 437
Query: 451 NKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAVRMAID 510
+KAI +S+ ++AGTVW+N Y PFGGF SG GRE+G YT+ K V + I
Sbjct: 438 DKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKIS 497
Query: 511 HPN 513
N
Sbjct: 498 QKN 500
>At1g23800 [C] KOG2450 Aldehyde dehydrogenase
Length = 508
Score = 449 bits (1156), Expect = e-126
Identities = 237/506 (46%), Positives = 322/506 (62%), Gaps = 4/506 (0%)
Query: 10 LRRFIRLYSQLPLKVPVQLPNGITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHI 69
+ R + YS L V + + E T L I G FV + KTF L+P N E I +
Sbjct: 1 MNRGAQRYSNLAAAVENTITPPVKVEH-TQLLIGGRFVDAVSGKTFPTLDPRNGEVIAQV 59
Query: 70 YEAREXXXXXXXXXXXXXFNNG-WSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGK 128
E F+ G W +R+K L + ADLI++H + +A++E+ DNGK
Sbjct: 60 SEGDAEDVNRAVAAARKAFDEGPWPKMTAYERSKILFRFADLIEKHNDEIAALETWDNGK 119
Query: 129 SLFCSRG-DVALVAKYLRSCAGWADKIYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPL 187
S +V ++A+ R AGWADKI+G + H T EP+GV GQIIPWNFPL
Sbjct: 120 PYEQSAQIEVPMLARVFRYYAGWADKIHGMTMPGDGPHHVQTLHEPIGVAGQIIPWNFPL 179
Query: 188 LMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERI 247
LM SWK+GPALA GNTVVLK AE TPLSAL +L+ EAG+P GVVNI+ GFG G I
Sbjct: 180 LMLSWKLGPALACGNTVVLKTAEQTPLSALLVGKLLHEAGLPDGVVNIVSGFGATAGAAI 239
Query: 248 CTHPDIKKVAFTGSTATGRHIMKTCADS-IKKVTLELGGKSPNIVFGDADLDKAVKNIAF 306
+H D+ KVAFTGST G+ I++ + S +K VTLELGGKSP IV DAD+D+AV+ F
Sbjct: 240 ASHMDVDKVAFTGSTDVGKIILELASKSNLKAVTLELGGKSPFIVCEDADVDQAVELAHF 299
Query: 307 GIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDK 366
+F+N G+ CCAGSR +V + VY+E +EK K A VG+PF+ + QG Q Q +K
Sbjct: 300 ALFFNQGQCCCAGSRTFVHERVYDEFVEKAKARALKRNVGDPFKSGIEQGPQVDSEQFNK 359
Query: 367 ILSYVDVGTSEGARVITGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTT 426
IL Y+ G GA + GG+R+G+KGY+I+PT+F+DVK+DM I +EIFGPV T+ KF
Sbjct: 360 ILKYIKHGVEAGATLQAGGDRLGSKGYYIQPTVFSDVKDDMLIATDEIFGPVQTILKFKD 419
Query: 427 VDEVVAKANDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSG 486
+DEV+A+AN+S YGLAAG+ T++++ A + ++ GTVWIN ++ ++PFGG+ SG
Sbjct: 420 LDEVIARANNSRYGLAAGVFTQNLDTAHRLMRALRVGTVWINCFDVLDASIPFGGYKMSG 479
Query: 487 IGREMGAEALDNYTQTKAVRMAIDHP 512
IGRE G +L+NY Q KAV ++ +P
Sbjct: 480 IGREKGIYSLNNYLQVKAVVTSLKNP 505
>Hs4502041 [C] KOG2450 Aldehyde dehydrogenase
Length = 512
Score = 435 bits (1119), Expect = e-122
Identities = 221/480 (46%), Positives = 308/480 (64%), Gaps = 4/480 (0%)
Query: 38 TGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNG--WSTA 95
T +FIN E+ S+ K F NPS E+I + E + F G W
Sbjct: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91
Query: 96 EPEDRAKCLLKLADLIDQHAETLASIESLDNGKS-LFCSRGDVALVAKYLRSCAGWADKI 154
+ R + L +LADL+++ TLA++E++D GK L D+ + LR AGWADKI
Sbjct: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151
Query: 155 YGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPL 214
GK I T + +T+ EP+GVCG I PWNFPLLM WK+ PAL GNT+VLKPAE TPL
Sbjct: 152 QGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211
Query: 215 SALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCAD 274
+ALY L++EAG P GVVNI+PGFG VG I +HP I K+AFTGST G+ + + +
Sbjct: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271
Query: 275 S-IKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVL 333
S +K+VTLELGGK+P IV DADLD AV+ G+F+N G+ C A SR++V++ VY E +
Sbjct: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331
Query: 334 EKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGY 393
+ +YA+ VG+PF+ QG Q Q Q DKIL ++ G EGA++ GG + +KG
Sbjct: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGL 391
Query: 394 FIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKA 453
FIKPT+F++V ++M+I KEEIFGPV + KF +++EV+ +AN ++YGL A + TK+++KA
Sbjct: 392 FIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKA 451
Query: 454 IDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAVRMAIDHPN 513
+ +++ +++GTVWIN YN + PFGGF SG GRE+G AL YT+ K V + + N
Sbjct: 452 LKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKN 511
>Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 429 bits (1104), Expect = e-120
Identities = 212/485 (43%), Positives = 310/485 (63%), Gaps = 9/485 (1%)
Query: 30 NGITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFN 89
N T P LFI GEFV + KT E +NP++ I + A+ F
Sbjct: 414 NKRTVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFE 473
Query: 90 NG-WSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCS-RGDVALVAKYLRSC 147
NG W DR + + +LADL++QH E LA+IE+LD G + + V + + R
Sbjct: 474 NGRWGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYF 533
Query: 148 AGWADKIYGKVIDTGAD----HFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNT 203
AGW DKI G I + + T++EP+GVCG IIPWN+PL+M SWK LA GNT
Sbjct: 534 AGWCDKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNT 593
Query: 204 VVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTA 263
VV+KPA+ TPL+AL +L +AG+PKGVVN++PG G +VG+R+ HPD++K+ FTGST
Sbjct: 594 VVIKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTE 653
Query: 264 TGRHIMKTCA-DSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRI 322
G+HIMK+CA ++KKV+LELGGKSP I+F D DL+KAV+ +F+N GE C A R+
Sbjct: 654 VGKHIMKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRL 713
Query: 323 YVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVI 382
+V+D++++E + + + +KVGNP + + G Q + K++ Y G EGA ++
Sbjct: 714 FVEDSIHDEFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLV 773
Query: 383 TGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFT--TVDEVVAKANDSEYG 440
GG ++ G+F +PT+F DV++ M I KEE FGPV+ +S+F +D V+++AN +E+G
Sbjct: 774 CGGNQVPRPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFG 833
Query: 441 LAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYT 500
LA+G+ T+D+NKA+ VS++++AGTV++NTYN PFGGF QSG G+++G AL+ Y
Sbjct: 834 LASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYL 893
Query: 501 QTKAV 505
+ K V
Sbjct: 894 RVKTV 898
>HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 426 bits (1095), Expect = e-119
Identities = 210/485 (43%), Positives = 310/485 (63%), Gaps = 9/485 (1%)
Query: 30 NGITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFN 89
N T P LFI GEFV + KT E +NP++ I + A+ F
Sbjct: 414 NKRTVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKGAFE 473
Query: 90 NG-WSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCS-RGDVALVAKYLRSC 147
NG W DR + + +LADL++QH E LA+IE+LD G + + V + + R
Sbjct: 474 NGRWGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYF 533
Query: 148 AGWADKIYGKVIDTGAD----HFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNT 203
AGW DKI G I + + T++EP+GVCG IIPWN+PL+M SWK LA GNT
Sbjct: 534 AGWCDKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNT 593
Query: 204 VVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTA 263
VV+KPA+ TPL+AL +L +AG+PKGVVN++PG G +VG+R+ HPD++K+ FTGST
Sbjct: 594 VVIKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTE 653
Query: 264 TGRHIMKTCA-DSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRI 322
G+HIMK+CA ++KKV+LELGG+SP I+F D DL+KAV+ +F++ GE C A R+
Sbjct: 654 VGKHIMKSCAISNVKKVSLELGGESPFIIFADCDLNKAVQMGMSSVFFSKGENCIAAGRL 713
Query: 323 YVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVI 382
+V+D++++E + + + +KVGNP + + G Q + K++ Y G EGA ++
Sbjct: 714 FVEDSIHDEFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLV 773
Query: 383 TGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFT--TVDEVVAKANDSEYG 440
GG ++ G+F +PT+F DV++ M I KEE FGPV+ +S+F +D V+++AN +E+G
Sbjct: 774 CGGNQVPRPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFG 833
Query: 441 LAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYT 500
LA+G+ T+D+NKA+ VS++++AGTV++NTYN PFGGF QSG G+++G AL+ Y
Sbjct: 834 LASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYL 893
Query: 501 QTKAV 505
+ K V
Sbjct: 894 RVKTV 898
>YMR170c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 422 bits (1085), Expect = e-118
Identities = 231/503 (45%), Positives = 309/503 (60%), Gaps = 11/503 (2%)
Query: 22 LKVPVQLPN-GITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXX 80
L +++P I+ +QP GLFIN EF PS KT E +NP+ E IT A E
Sbjct: 4 LYTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKA 63
Query: 81 XXXXXXXFNNGWSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCS-RGDVAL 139
F+N WS E R L L LI++ +TLA++E+LD GK + +GD+A
Sbjct: 64 VKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQ 123
Query: 140 VAKYLRSCAGWADKI-YGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPAL 198
+ + R AG ADK G I + F+YT + P GV QI+PWN+PL M WK+ AL
Sbjct: 124 ILQLTRYFAGSADKFDKGATIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACWKLQGAL 183
Query: 199 ATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAF 258
A GNTV++KPAE T LS LY L+++AG P GVVNI+PG+G +VG+ + +H DI K++F
Sbjct: 184 AAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNIVPGYGSLVGQALASHMDIDKISF 243
Query: 259 TGSTATGRHIMKTCADS-IKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCC 317
TGST G +++ S +K VTLE GGKSP +VF DADLDKA+ IA GIFYNSG+ C
Sbjct: 244 TGSTKVGGFVLEASGQSNLKDVTLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCT 303
Query: 318 AGSRIYVQDTVYEEVLEKFKQYAES----LKVGNPFEENVFQGAQTSQMQIDKILSYVDV 373
A SR+YVQ ++Y++ +EKFK+ A+ +PF+E G S Q D+I SY++
Sbjct: 304 ANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIER 363
Query: 374 GTSEGARVITGGERI---GNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEV 430
G E + G KGYFI PTIF DV + +++++EIFGPVV VSKFT D+
Sbjct: 364 GKREEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTNYDDA 423
Query: 431 VAKANDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGRE 490
+ AND+ YGLA+ + TKDV KA + +KAGTVWIN+ N+ VPFGGF SGIGRE
Sbjct: 424 LKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINSSNDEDVTVPFGGFKMSGIGRE 483
Query: 491 MGAEALDNYTQTKAVRMAIDHPN 513
+G +D Y QTKAV + + N
Sbjct: 484 LGQSGVDTYLQTKAVHINLSLDN 506
>YMR169c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 412 bits (1059), Expect = e-115
Identities = 225/497 (45%), Positives = 304/497 (60%), Gaps = 11/497 (2%)
Query: 22 LKVPVQLPN-GITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXX 80
L +++P I+ +QP GLFIN EF PS KT E +NP+ E IT A E
Sbjct: 4 LYTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKA 63
Query: 81 XXXXXXXFNNGWSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCS-RGDVAL 139
F+N WS E R L L LI++ +TLA++E+LD GK + + D+A
Sbjct: 64 VKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQ 123
Query: 140 VAKYLRSCAGWADKI-YGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPAL 198
+ + R AG DK G+ I + F+YT + P GV QI+PWN+PL M K+ AL
Sbjct: 124 IIELTRYYAGAVDKFNMGETIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACRKMQGAL 183
Query: 199 ATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAF 258
A GNTV++KPAE T LS LY L+++AG P GVVN+IPG+G +VG+ + TH DI K++F
Sbjct: 184 AAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNVIPGYGSVVGKALGTHMDIDKISF 243
Query: 259 TGSTATGRHIMKTCADS-IKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCC 317
TGST G +++ S +K +TLE GGKSP +VF DADLDKA++ +A GIF+NSG++C
Sbjct: 244 TGSTKVGGSVLEASGQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICT 303
Query: 318 AGSRIYVQDTVYEEVLEKFKQYAES----LKVGNPFEENVFQGAQTSQMQIDKILSYVDV 373
A SR+YVQ ++Y++ +EKFK+ A+ +PF+E G S Q D+I SY++
Sbjct: 304 ANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIER 363
Query: 374 GTSEGARVITGGERI---GNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEV 430
G E + G KGYFI PTIF DV E +++++EIFGPVV VSKFT D+
Sbjct: 364 GKKEEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDDA 423
Query: 431 VAKANDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGRE 490
+ AND+ YGLA+ + TKDV KA + +KAGTVWIN N VPFGGF SGIGRE
Sbjct: 424 LKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINQTNQEEAKVPFGGFKMSGIGRE 483
Query: 491 MGAEALDNYTQTKAVRM 507
G +DNY Q K+V +
Sbjct: 484 SGDTGVDNYLQIKSVHV 500
>Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 975
Score = 407 bits (1047), Expect = e-113
Identities = 199/472 (42%), Positives = 303/472 (64%), Gaps = 9/472 (1%)
Query: 30 NGITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFN 89
N I + P FING+F + KT++ +NP++ I + A F
Sbjct: 435 NEIMVKMPYQCFINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFE 494
Query: 90 NG-WSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCS-RGDVALVAKYLRSC 147
NG W +R + + +LADL++++ E LA+IE+LD+G + + + + + R
Sbjct: 495 NGEWGRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYF 554
Query: 148 AGWADKIYGKVIDTGAD----HFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNT 203
AGW DKI G I + ++TK+EPLGVC IIPWN+PL+M +WK LA GNT
Sbjct: 555 AGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNT 614
Query: 204 VVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTA 263
+VLKPA+ TPL+AL +L +AG PKGV+NIIPG G I G+R+ HPDI+K+ FTGST
Sbjct: 615 LVLKPAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTP 674
Query: 264 TGRHIMKTCA-DSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRI 322
G+ IMK+CA ++KKV+LELGGKSP I+F D +LDKAV+ +F+N GE C A R+
Sbjct: 675 IGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRL 734
Query: 323 YVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVI 382
+V++++++E + + + + +K+G+P + + G Q + ++K+L Y + G EGA ++
Sbjct: 735 FVEESIHDEFVTRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLV 794
Query: 383 TGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTT--VDEVVAKANDSEYG 440
GG ++ G+F++PT+F DV++ M + KEE FGP++ +SKF +D V+ +AN +EYG
Sbjct: 795 YGGRQVQRPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYG 854
Query: 441 LAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMG 492
LA+G+ T+D+NKA+ VS +++AGTV+INTYN PFGG QSG G+++G
Sbjct: 855 LASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLG 906
>CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 887
Score = 344 bits (882), Expect = 2e-94
Identities = 181/485 (37%), Positives = 280/485 (57%), Gaps = 30/485 (6%)
Query: 30 NGITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFN 89
N + + P FI+G+FV S +TF+ +NP+ E+ I + A F
Sbjct: 420 NNMELKFPHDQFIDGKFVGSSDGRTFKTINPATEKPICELPLATVADVDRAVRAAKKAFE 479
Query: 90 NG-WSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCS-RGDVALVAKYLRSC 147
G W +R K L KLA+L+++H E LA++ESLD G + + V + R
Sbjct: 480 RGEWRQMSARERGKRLYKLAELMEEHKEELATLESLDAGAVYTLALKTHVGMSIDVWRYF 539
Query: 148 AGWADKIYGKVIDTGA----DHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNT 203
AGW DKI GK I + T REP+GV G I PWN+PL+M SWK+ LA
Sbjct: 540 AGWCDKIQGKTIPISNARPNKNLCLTLREPIGVVGLITPWNYPLMMLSWKMAACLAAAKI 599
Query: 204 VVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTA 263
+++ + GV+NI+ G G +VG R+ HPD++K+ FTGST
Sbjct: 600 KLIEIS---------------------GVINIVTGSGSLVGNRLTAHPDVRKIGFTGSTE 638
Query: 264 TGRHIMKTCADS-IKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRI 322
G +M++CA S IKKV+LELGGKSP I+F DADL+KAVK +F+N GE C A R+
Sbjct: 639 IGATVMESCAKSNIKKVSLELGGKSPLIIFADADLEKAVKQACGAVFFNKGENCIAAGRV 698
Query: 323 YVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVI 382
++ +++++ ++K + A+ ++G+P + + G Q ++K++ YV+ + GA+V
Sbjct: 699 FIAKSIHDDFVKKLVEEAKQYQIGDPLDRSTAHGPQNHLAHLNKLVEYVEKAVAGGAKVE 758
Query: 383 TGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKF--TTVDEVVAKANDSEYG 440
GG+R+ +G + PTI +++ ++ EE FGP++ VS F +++V+ +AND+E+G
Sbjct: 759 VGGKRLEREGLYFPPTILSNIDDENFAASEESFGPIMCVSSFDDDDIEDVLRRANDTEFG 818
Query: 441 LAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYT 500
LAAG+ T+D +K++ V+ + AGTV++NTY PFGGF QSG G++MG EAL+ Y
Sbjct: 819 LAAGVFTRDSSKSLRVAEALHAGTVFVNTYQKTDVAAPFGGFKQSGFGKDMGEEALNEYL 878
Query: 501 QTKAV 505
TK +
Sbjct: 879 VTKTI 883
>Hs4502047 [C] KOG2450 Aldehyde dehydrogenase
Length = 493
Score = 341 bits (874), Expect = 2e-93
Identities = 171/420 (40%), Positives = 260/420 (61%), Gaps = 7/420 (1%)
Query: 92 WSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAKYLRSCAGWA 151
WS +R + LL+ A +I + + +A++E ++NGKS+F +R D+ + + L AG A
Sbjct: 64 WSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLA 123
Query: 152 DKIYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEA 211
+ G+ I F YT+REPLGVC I WN+P + SWK PALA GN +V KP+
Sbjct: 124 ASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPF 183
Query: 212 TPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKT 271
TP+SAL ++ EAGVP G+ N++ G G G+ +C HPD+ KV+FTGS TG IM+
Sbjct: 184 TPVSALLLAEIYSEAGVPPGLFNVVQG-GAATGQFLCQHPDVAKVSFTGSVPTGMKIMEM 242
Query: 272 CADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEE 331
A IK VTLELGGKSP I+F D D++ AVK F G+VCC G+R++VQ + ++
Sbjct: 243 SAKGIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDK 302
Query: 332 VLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIG-- 389
E+ + + +K+G+P E+ G ++ ++++L +V V +GA+V+ GG+
Sbjct: 303 FTEEVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPE 362
Query: 390 ----NKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGI 445
GY+++P + + ++DM VKEEIFGPV+++ F T EV+ +AND+ +GLAAG+
Sbjct: 363 DPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGV 422
Query: 446 HTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAV 505
T+D+ +A V ++AGT +IN YN +PFGG+ +SG GRE G ++ Y+Q K V
Sbjct: 423 FTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTV 482
>At3g48170 [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 336 bits (861), Expect = 6e-92
Identities = 190/484 (39%), Positives = 272/484 (55%), Gaps = 11/484 (2%)
Query: 40 LFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXF--NNG--WSTA 95
LFI G++ KT V+NP+ E+ I +I A F NNG W+ A
Sbjct: 10 LFIGGQWTEPVLRKTLPVVNPATEDIIGYIPAATSEDVELAVEAARKAFTRNNGKDWARA 69
Query: 96 EPEDRAKCLLKLADLIDQHAETLASIESLDNGKSL---FCSRGDVALVAKYLRSCAGWAD 152
RAK L +A + + LA++E++D GK L DVA +Y A D
Sbjct: 70 TGAVRAKYLRAIAAKVIERKSELANLEAIDCGKPLDEAAWDMDDVAGCFEYYADLAEGLD 129
Query: 153 KIYGKVIDTGADHFS-YTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEA 211
+ D F Y +EP+GV G I PWN+PLLM WKV P+LA G T +LKP+E
Sbjct: 130 AKQKTPLSLPMDTFKGYILKEPIGVVGMITPWNYPLLMAVWKVAPSLAAGCTAILKPSEL 189
Query: 212 TPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKT 271
L+ L + +E G+P GV+NI+ G G G + +HP + K+ FTGST TG IM +
Sbjct: 190 ASLTCLELADICREVGLPPGVLNILTGLGTEAGAPLASHPHVDKIVFTGSTTTGSSIMTS 249
Query: 272 CADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEE 331
A +K V+LELGGKSP IVF D D+DKAV+ FG F+ +G++C A SR+ V + + +E
Sbjct: 250 AAKLVKPVSLELGGKSPIIVFDDVDIDKAVEWTMFGCFWTNGQICSATSRLLVHERIADE 309
Query: 332 VLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGN- 390
L+K ++ +++K+ +PFEE G S+ Q +++L +V +EGA V+ GG R +
Sbjct: 310 FLDKLVKWTKNIKISDPFEEGCRLGPVVSKGQYERVLKFVSNARNEGATVLCGGVRPEHL 369
Query: 391 -KGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKD 449
KGYF++P I ++V M+I +EE+FGP + V F+T DE + ANDS+YGLA + + D
Sbjct: 370 KKGYFVEPAIVSNVTTSMEIWREEVFGPALCVKTFSTEDEAIQLANDSQYGLAGAVLSND 429
Query: 450 VNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAVRMAI 509
+ + VS +AG VW+N P+GG +SG GRE+G L+NY K V I
Sbjct: 430 LERCDRVSKAFQAGIVWVNCSQPCFCQAPWGGTKRSGFGRELGEWGLENYLSVKQVTQYI 489
Query: 510 -DHP 512
D P
Sbjct: 490 SDEP 493
>At1g79440 [C] KOG2451 Aldehyde dehydrogenase
Length = 528
Score = 324 bits (830), Expect = 2e-88
Identities = 179/465 (38%), Positives = 268/465 (57%), Gaps = 2/465 (0%)
Query: 42 INGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAEPEDRA 101
I G+++ S +KT +V NP+ E I + F + WS +R+
Sbjct: 57 IGGKWLDSYDNKTIKVNNPATGEIIADVACMGTKETNDAIASSYEAFTS-WSRLTAGERS 115
Query: 102 KCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGKVIDT 161
K L + DL+ H E L + +L+ GK L + G+VA A ++ A A ++YG +I
Sbjct: 116 KVLRRWYDLLIAHKEELGQLITLEQGKPLKEAIGEVAYGASFIEYYAEEAKRVYGDIIPP 175
Query: 162 G-ADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYAC 220
+D ++P+GV G I PWNFPL M + KVGPALA+G TVV+KP+E TPL+AL A
Sbjct: 176 NLSDRRLLVLKQPVGVVGAITPWNFPLAMITRKVGPALASGCTVVVKPSELTPLTALAAA 235
Query: 221 QLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIKKVT 280
+L +AGVP G +N++ G +G+ + T P ++K+ FTGSTA G+ +M A ++KKV+
Sbjct: 236 ELALQAGVPPGALNVVMGNAPEIGDALLTSPQVRKITFTGSTAVGKKLMAAAAPTVKKVS 295
Query: 281 LELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQYA 340
LELGG +P+IVF DADLD AVK F NSG+ C +R+ VQD +Y++ E F +
Sbjct: 296 LELGGNAPSIVFDDADLDVAVKGTLAAKFRNSGQTCVCANRVLVQDGIYDKFAEAFSEAV 355
Query: 341 ESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGYFIKPTIF 400
+ L+VG+ F + QG + + K+ ++V S+GA++I GG+R F +PT+
Sbjct: 356 QKLEVGDGFRDGTTQGPLINDAAVQKVETFVQDAVSKGAKIIIGGKRHSLGMTFYEPTVI 415
Query: 401 ADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAIDVSNRV 460
DV ++M + KEEIFGPV + +F T ++ + AND+ GLAA I T V ++ V +
Sbjct: 416 RDVSDNMIMSKEEIFGPVAPLIRFKTEEDAIRIANDTIAGLAAYIFTNSVQRSWRVFEAL 475
Query: 461 KAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAV 505
+ G V +N + PFGG QSG+GRE +D Y + K V
Sbjct: 476 EYGLVGVNEGLISTEVAPFGGVKQSGLGREGSKYGMDEYLEIKYV 520
>CE07233 [C] KOG2450 Aldehyde dehydrogenase
Length = 687
Score = 320 bits (821), Expect = 2e-87
Identities = 173/471 (36%), Positives = 264/471 (55%), Gaps = 9/471 (1%)
Query: 41 FINGEFVPSRQHKTFEVLNP-SNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAEPED 99
F+ G V + FEV+ P S + T Y R+ W+ + +
Sbjct: 209 FVAGNHVEFPSDRKFEVIEPRSGKPMATWHYATRDQVDLTVKEAKKA--QKQWAKSSWME 266
Query: 100 RAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGKVI 159
R++ L K DL+ H +A E + NGK + ++ DV +G A + G+ +
Sbjct: 267 RSEILKKTGDLLKTHCNDIAYWECISNGKPIAEAKADVLSCVDTFYFYSGIASDLLGQHV 326
Query: 160 DTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYA 219
A ++YT+R P+GV I WN+P+ SWK PALA GN V+ KP+ +P++AL
Sbjct: 327 PLDASRYAYTRRLPVGVVAAIGAWNYPIQTCSWKTAPALACGNAVIYKPSPLSPVTALIL 386
Query: 220 CQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCAD-SIKK 278
++++ AG+P GV N+I G + + I H + KV+FTGS TG+ IMK CAD +IK
Sbjct: 387 AEILKSAGLPDGVFNVIQGDAETAQDLI-HHDGVSKVSFTGSIPTGKKIMKACADRNIKP 445
Query: 279 VTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQ 338
VTLELGGKS IVF DAD+D AV FY+ G+VC S++ V +V +E +K
Sbjct: 446 VTLELGGKSALIVFDDADIDSAVSCAMMANFYSQGQVCSNASKVLVHKSVLKEFTKKLVD 505
Query: 339 YAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIG----NKGYF 394
+ + +K+G+P +E+ G+ S +K+ Y+ +EGA + GG+R+ G++
Sbjct: 506 HTQKMKIGDPLKEDTQVGSHISAEHRNKVEGYISTAIAEGATKLCGGDRVAVHGLENGFY 565
Query: 395 IKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAI 454
+ P I + M + +EEIFG V+ + F T DE + AND++ GLAAG+ TKD++++
Sbjct: 566 LSPCILTGITPKMTVYREEIFGSVLLIIPFDTEDEAIKIANDTDMGLAAGLVTKDLSRSY 625
Query: 455 DVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAV 505
VS ++ AG V++NTYN+ VPFGG G+SG GRE G L++YT K+V
Sbjct: 626 RVSEQLNAGNVYVNTYNDVSPLVPFGGVGESGFGRENGTAVLEHYTHLKSV 676
>Hs12007648 [C] KOG2450 Aldehyde dehydrogenase
Length = 487
Score = 315 bits (807), Expect = 1e-85
Identities = 175/476 (36%), Positives = 271/476 (56%), Gaps = 16/476 (3%)
Query: 41 FINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAEPEDR 100
FI+G+F+P + + +PS E + + + F + WS+ P++R
Sbjct: 13 FIDGKFLPCSSY--IDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPS-WSSRSPQER 69
Query: 101 AKCLLKLADLIDQHAETLASIESLDNGKSLFCSRG-DVALVAKYLRSCAGWADKIYGKVI 159
++ L ++ADL++Q E A ES D GK+L +R D+ + R A + ++
Sbjct: 70 SRVLNQVADLLEQSLEEFAQAESKDQGKTLALARTMDIPRSVQNFRFFA--SSSLHHTSE 127
Query: 160 DTGADHFS---YTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSA 216
T DH YT R P+GV G I PWN PL + +WK+ PA+A GNTV+ KP+E T ++A
Sbjct: 128 CTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSVTA 187
Query: 217 LYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSI 276
C+L+ +AGVP GVVNI+ G G VGE + +HP++ ++FTGS T I + A
Sbjct: 188 WMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHC 247
Query: 277 KKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKF 336
KK++LELGGK+P I+F DA+LD+ + F N GE+C SRI+VQ ++Y E L++F
Sbjct: 248 KKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFLKRF 307
Query: 337 KQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGG-------ERIG 389
+ KVG P + V GA S+ ++K+ SYV +EGA++ G
Sbjct: 308 VEATRKWKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLPARN 367
Query: 390 NKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKD 449
GYF+ PT+ D+K++ + EEIFGPV V F + +EV+ +AN+ +YGLAA + + +
Sbjct: 368 QAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSN 427
Query: 450 VNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAV 505
V + V+ ++++G VW N + N+PFGG SGIGRE ++ D +T+ K +
Sbjct: 428 VGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTI 483
>At1g74920 [C] KOG2450 Aldehyde dehydrogenase
Length = 481
Score = 305 bits (780), Expect = 1e-82
Identities = 175/482 (36%), Positives = 255/482 (52%), Gaps = 38/482 (7%)
Query: 40 LFINGEFVPSRQHKTFEVLNPSNEEEITHIYE--------AREXXXXXXXXXXXXXFNNG 91
LFI+GE+ K ++NP+ EE++ + E + N G
Sbjct: 10 LFIDGEWREPILKKRIPIVNPATEEDLYVLDEIGDIPAATTEDVDVAVNAARRALSRNKG 69
Query: 92 --WSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSL---FCSRGDVALVAKYLRS 146
W+ A RAK L +A +++ LA +E+LD GK L DVA ++
Sbjct: 70 KDWAKAPGAVRAKYLRAIAAKVNERKTDLAKLEALDCGKPLDEAVWDMDDVAGCFEFYAD 129
Query: 147 CAGWADKIYGKVIDTGADHF-SYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVV 205
A D + + F SY ++PLGV G I PWN+PLLM WKV P+LA G T +
Sbjct: 130 LAEGLDAKQKAPVSLPMESFKSYVLKQPLGVVGLITPWNYPLLMAVWKVAPSLAAGCTAI 189
Query: 206 LKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATG 265
LKP+E ++ L + +E G+P GV+N++ GFG G + +HP + K+AFTGS ATG
Sbjct: 190 LKPSELASVTCLELADICREVGLPPGVLNVLTGFGSEAGAPLASHPGVDKIAFTGSFATG 249
Query: 266 RHIMKTCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQ 325
+M A +K V++ELGGKSP IVF D DLDKA + FG F+ +G++C A SR+ V
Sbjct: 250 SKVMTAAAQLVKPVSMELGGKSPLIVFDDVDLDKAAEWALFGCFWTNGQICSATSRLLVH 309
Query: 326 DTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGG 385
+++ E +EK ++++++K+ +P EE G V++ G
Sbjct: 310 ESIASEFIEKLVKWSKNIKISDPMEEGCRLGP-----------------------VVSKG 346
Query: 386 ERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGI 445
+ + KG+FI+PTI DV MQI +EE+FGPV+ V F + DE + ANDS YGL A +
Sbjct: 347 QHL-EKGFFIEPTIITDVTTSMQIWREEVFGPVLCVKTFASEDEAIELANDSHYGLGAAV 405
Query: 446 HTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAV 505
+ D + +S +AG VWIN P+GG +SG GRE+G LDNY K V
Sbjct: 406 ISNDTERCDRISEAFEAGIVWINCSQPCFTQAPWGGVKRSGFGRELGEWGLDNYLSVKQV 465
Query: 506 RM 507
+
Sbjct: 466 TL 467
>7301355 [C] KOG2451 Aldehyde dehydrogenase
Length = 509
Score = 304 bits (778), Expect = 2e-82
Identities = 167/471 (35%), Positives = 271/471 (57%), Gaps = 5/471 (1%)
Query: 42 INGEFVPSRQHK-TFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNG-WSTAEPED 99
++G +V S K TFEV NP+N I + + + W + +D
Sbjct: 33 VDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYESKEWRSLTAKD 92
Query: 100 RAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGKVI 159
R+ L K LI+QH++ +A I + ++GK + S+G+VA ++ A A +IYG+++
Sbjct: 93 RSNLLKKWHKLIEQHSQEIAEIMTAESGKPINESKGEVAYGNAFVEWFAEEARRIYGEIV 152
Query: 160 DTGADHFSY-TKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALY 218
+ + + ++P+GV I PWNFP+ M + K G ALA G TVV+KP+E TPL+AL
Sbjct: 153 PSASPNREIIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALA 212
Query: 219 ACQLVQEAGVPKGVVNIIP-GFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIK 277
+L +AG+PKGV+N++ +G+ C PD++ ++FTGST G+ + + AD IK
Sbjct: 213 VAKLAVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSADGIK 272
Query: 278 KVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFK 337
++ LELGG +P IVF AD++KAV F N G+ C + +R +VQD+VY++ + + K
Sbjct: 273 RICLELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLK 332
Query: 338 QYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKG-YFIK 396
+ E+LK+G+ +V G ++MQ +K+ +V+ S+ A +I GG+ + +KG F
Sbjct: 333 KRVEALKIGDGQGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDKGSLFYA 392
Query: 397 PTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAIDV 456
PTI DV Q+ EE+FGPVV++ +F +E V KAND+ GLA +++++ + V
Sbjct: 393 PTIVTDVPPSAQLYSEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRV 452
Query: 457 SNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAVRM 507
+ R++ G V +N PFGG +SG+GRE +D+Y K + M
Sbjct: 453 AKRLEVGMVGVNEGIISAAEAPFGGVKESGVGREGSKHGIDDYVDIKYICM 503
>CE24573 [C] KOG2450 Aldehyde dehydrogenase
Length = 574
Score = 302 bits (774), Expect = 7e-82
Identities = 184/498 (36%), Positives = 271/498 (53%), Gaps = 19/498 (3%)
Query: 18 SQLPLKVPVQLPNGITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXX 77
S++ VP L G+ F+NG+ +TF+V+ P + + +A
Sbjct: 74 SKMVFTVPSDLSGGL-------YFLNGKRTTIESTETFDVIEPRIGQVVAKCPKATADIV 126
Query: 78 XXXXXXXXXXFNNGWSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDV 137
+ W DR K L K+ADLI +HAE +A E NGK ++ +R D+
Sbjct: 127 DQYVKAAADA-QSAWGETTALDRGKVLHKVADLIREHAEEIAIWEVKTNGKPIYEARCDI 185
Query: 138 ALVAKYLRSCAGWADKIY-GKVIDTG---ADHFSYTKREPLGVCGQIIPWNFPLLMWSWK 193
A A G A + G ++ + +YT+REP GV G I WN+P WK
Sbjct: 186 ASSADTFDFFGGIATAVLQGDSLELPGGPSQRIAYTRREPYGVVGCIGAWNYPFQTCVWK 245
Query: 194 VGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDI 253
V PALA GN VV KP+ P S + +++ AGVPKGV N+I G + G +C H +
Sbjct: 246 VAPALAAGNAVVYKPSPFAPASPVLLGEILTAAGVPKGVYNVIQGEQE-AGVALCEHNLV 304
Query: 254 KKVAFTGSTATGRHIMKTCAD-SIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNS 312
KV+FTGS A+G + + A ++K VTLELGGKS I+F D+D+ AV + F N
Sbjct: 305 AKVSFTGSVASGEAVQRQAATKNVKPVTLELGGKSEIIIFDDSDVKSAVASAMLANFLNQ 364
Query: 313 GEVCCAGSRIYVQDTVYEEVLEKFKQYA-ESLKVGNPFEENVFQGAQTSQMQIDKILSYV 371
G+VC +R++VQ + E Q A + LKVG+P E+ GA ++ + +IL YV
Sbjct: 365 GQVCTNATRVFVQKGILASFTEAIVQEANDKLKVGDPLLEDTRVGANINEGHLQRILGYV 424
Query: 372 DVGTSEGARVITGGERIGNKGY----FIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTV 427
+ EG V+ GG R+ G + +P I + ++ + V+EEIFG V+ + F T
Sbjct: 425 ESAKQEGGVVLRGGVRVHPTGVEGGAYFEPAIITGLSDEARAVREEIFGAVMLILPFETE 484
Query: 428 DEVVAKANDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGI 487
+EV+A+AN++ YGLAAG+ + ++ + V+ R++AGTV+INTYN+ NVPFGGF SG
Sbjct: 485 EEVIARANNTTYGLAAGVFSGNLARGHRVAARLQAGTVFINTYNDTEVNVPFGGFKNSGH 544
Query: 488 GREMGAEALDNYTQTKAV 505
GRE + L +TQTKA+
Sbjct: 545 GRENCIDTLRAHTQTKAI 562
>SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 300 bits (768), Expect = 3e-81
Identities = 178/473 (37%), Positives = 258/473 (53%), Gaps = 7/473 (1%)
Query: 40 LFINGEFVPSRQH--KTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNG-WSTAE 96
LFI+G+FV + K ++NP+ EE I A F +G W+
Sbjct: 23 LFIDGKFVSPIEPAAKPIPLINPATEEIIGTCANASAKDVDSAVENAYNTFRSGIWAKWP 82
Query: 97 PEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVA---KYLRSCAGWADK 153
+ R L K+A ++ + E LA I++++ GK + D+ A +Y A +
Sbjct: 83 GKQRGLVLRKIAKMMREKRELLAGIDTINCGKPTPYALFDIDSCADMFEYYAEVAETDNP 142
Query: 154 IYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATP 213
+ ++ KR P GV G I PWNFPL M WK+ PA+A+GN VVLKP+E P
Sbjct: 143 TVKVPLPNNPGFCAFEKRFPRGVIGVITPWNFPLKMALWKLVPAIASGNCVVLKPSELAP 202
Query: 214 LSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCA 273
S L + +EAG+P GV+N+I G GK G + HP I +AFTGS ATG+ IM A
Sbjct: 203 WSCLEFALICKEAGLPDGVLNVIIGSGKESGAALSCHPKIAYLAFTGSLATGKKIMHAAA 262
Query: 274 DSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVL 333
++I +TLELGGKSP I+ DADL A+ + AF IF+N GE C A SR+ V ++V +EVL
Sbjct: 263 ENIVPLTLELGGKSPLIICEDADLSLAIPSAAFAIFFNQGEACTAASRLIVHESVADEVL 322
Query: 334 EKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGG-ERIGNKG 392
A L +GN + V G S+ Q +KI+SY+ +EG + + GG R KG
Sbjct: 323 GGLVSEANKLIIGNGLDPQVTLGPVVSKTQFEKIVSYIQSAINEGCKCVVGGLPRSEQKG 382
Query: 393 YFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNK 452
YFI PT+F +V+ +I +EEIFGPV+ V F T +E + ANDSEYGL +G+ + +
Sbjct: 383 YFIPPTVFTNVQTHNKIWREEIFGPVLAVKTFHTNEEALELANDSEYGLGSGVFSTNPKT 442
Query: 453 AIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAV 505
SN ++AG +N Y+ +P+ G+ SG+G + + Y + K +
Sbjct: 443 LEFFSNNIEAGMCSLNNYHVVTHELPWIGWKHSGLGVGLSKHGYNEYMRLKQI 495
>7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 816
Score = 290 bits (743), Expect = 3e-78
Identities = 145/372 (38%), Positives = 220/372 (58%), Gaps = 7/372 (1%)
Query: 37 PTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAE 96
PT LFINGEFV + +T E++NP+NEE + + A F W
Sbjct: 428 PTQLFINGEFVDAEAQRTLEIVNPTNEEVLCKVACASATDVDKAVRAAHSAFYGSWRQIT 487
Query: 97 PEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCS-RGDVALVAKYLRSCAGWADKIY 155
P R + +L LADL++++ E LA+IES+D+G + + V + + R AGW DKI
Sbjct: 488 PRQRGQLMLNLADLMERNKEELATIESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKIQ 547
Query: 156 GKVIDTGADH----FSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEA 211
G I ++T++EP+GVCG I PWN+PL+M SWK+ +A GNT ++KPA+
Sbjct: 548 GNTIPVNPARPNNVLTFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQT 607
Query: 212 TPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKT 271
PL+AL +L AG P GV+N++PG G G+ + H ++K+ FTGST G+HIMK+
Sbjct: 608 CPLTALKFAELTVRAGFPPGVINVLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMKS 667
Query: 272 CADS-IKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYE 330
CADS +KK +LELGGKSP I+F D D+DKAVK+ +F+N GE C A R++V+D +++
Sbjct: 668 CADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHD 727
Query: 331 EVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGN 390
E + + + ++ +G+P + + G Q + DK+L + G EGA+++ ER G
Sbjct: 728 EFIRRVLKDLRTMTIGDPLDRSTAHGPQNHKAHFDKLLEFCRRGVDEGAKLVV-YERYGR 786
Query: 391 KGYFIKPTIFAD 402
Y + ++ D
Sbjct: 787 YVYCPRGVLWTD 798
>Hs4507229 [C] KOG2451 Aldehyde dehydrogenase
Length = 535
Score = 286 bits (731), Expect = 7e-77
Identities = 168/473 (35%), Positives = 264/473 (55%), Gaps = 8/473 (1%)
Query: 38 TGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAEP 97
T F+ G ++P+ TF V +P++ + + + F W
Sbjct: 61 TDSFVGGRWLPAAA--TFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCR-WREVSA 117
Query: 98 EDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGK 157
++R+ L K +L+ Q+ + LA I + ++GK L + G++ A +L + A ++YG
Sbjct: 118 KERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGD 177
Query: 158 VIDTGA-DHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSA 216
+I T A D + ++P+GV I PWNFP M + KVG ALA G TVV+KPAE TP SA
Sbjct: 178 IIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSA 237
Query: 217 LYACQLVQEAGVPKGVVNIIPGF---GKIVGERICTHPDIKKVAFTGSTATGRHIMKTCA 273
L +L +AG+P GV N+IP K VGE ICT P + K++FTGST TG+ ++ A
Sbjct: 238 LALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAA 297
Query: 274 DSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVL 333
+S+K+V++ELGG +P IVF A++D+AV F N+G+ C ++ VQ +++ +
Sbjct: 298 NSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFV 357
Query: 334 EKFKQ-YAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKG 392
+ F + ++L+VGN FEE QG ++ ++K+ V+ S+GA V+TGG+R
Sbjct: 358 KAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGK 417
Query: 393 YFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNK 452
F +PT+ +V +DM EE FGP+ V KF T +E +A AN ++ GLA +++D +
Sbjct: 418 NFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQ 477
Query: 453 AIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAV 505
V+ +++ G V +N PFGG QSG+GRE +D Y + K V
Sbjct: 478 IWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYV 530
>SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase
Length = 498
Score = 284 bits (726), Expect = 3e-76
Identities = 170/477 (35%), Positives = 264/477 (54%), Gaps = 4/477 (0%)
Query: 35 EQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWST 94
E P +I G++V + KTF+V NP E + + + F + +
Sbjct: 21 EFPARSYIGGKWVTAASGKTFDVENPGLNETLAPVTDMSVEETRKAIKVAHEAFLS-YRN 79
Query: 95 AEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAKYLRSCAGWADKI 154
++ ++R L + DLI ++A+ LA++ +L+NGK+L ++G+V AK++ AG A +I
Sbjct: 80 SDIKERYAILRRWYDLIMENADDLATMMTLENGKALGDAKGEVVYAAKFIDWFAGEALRI 139
Query: 155 YG-KVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATP 213
G + + + T ++P+GV G I PWNFP M + KVG ALA G TVV++PA TP
Sbjct: 140 SGDSSMSSNPQNRIITIKQPVGVVGIITPWNFPAAMITRKVGAALAAGCTVVIRPAAETP 199
Query: 214 LSALYACQLVQEAGVPKGVVNIIPGFGKIV-GERICTHPDIKKVAFTGSTATGRHIMKTC 272
+AL +L + AGVP GV+N++ G + T+P I+KV+FTGST G+ + K
Sbjct: 200 FTALALAKLAERAGVPAGVLNMVTANSPSEHGIELTTNPLIRKVSFTGSTNVGKILAKQS 259
Query: 273 ADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEV 332
+ ++KK++LELGG +P IVF DADL+KA + F SG+ C +RIYV +VY+
Sbjct: 260 SSTLKKLSLELGGNAPFIVFEDADLEKAADALMACKFRGSGQTCVCANRIYVHSSVYDAF 319
Query: 333 LEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKG 392
++ + K+G + V G S+ I K+ +V+ +G V+TGG+ N G
Sbjct: 320 VDLVTERVSKFKLGYGLDAGVTHGPLISEKAISKVKQHVEDAVQKGGVVVTGGKVASNLG 379
Query: 393 -YFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVN 451
+ +PT+ + K+ M I +EE FGPV + KF T DEVVA ANDS GLA + +KD++
Sbjct: 380 PMYFEPTVIINAKQGMLISEEETFGPVGALFKFDTEDEVVAWANDSPVGLAGYLFSKDIS 439
Query: 452 KAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAVRMA 508
+ V ++ G V NT PFGG +SG GRE + Y K++ ++
Sbjct: 440 RVFRVGEALQVGMVGCNTGLVSDVLSPFGGVKESGFGREGSKYGISEYLDIKSLTIS 496
>CE06980 [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 280 bits (717), Expect = 3e-75
Identities = 164/484 (33%), Positives = 263/484 (53%), Gaps = 27/484 (5%)
Query: 37 PTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAE 96
P FI EF +R K + +NPS + I + F W
Sbjct: 27 PLTNFIGNEF--ARSEKLMDSVNPSTGKPWIKIPDGTAREVDQAVEAAKEAFKT-WKKTT 83
Query: 97 PEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSR-----------GDVALVAKYLR 145
+ R+ L K+A+LI++ + +A +ES D GK + ++ D A A Y
Sbjct: 84 VQQRSALLNKVANLIEEFNDDIAILESRDQGKPIGLAKVMDIPRCVQNFRDFANAALYSL 143
Query: 146 SCAGWADKIYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVV 205
S + ++ GK ++ Y K +P+GV G I PWN PL + S+K+ PAL GNTVV
Sbjct: 144 STSTILEQPTGKFVN-------YVKNDPVGVAGLISPWNLPLYLLSFKLAPALVAGNTVV 196
Query: 206 LKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATG 265
KP+E T ++A + G P GVVN++ G GK G+R+ H D+ ++FTGST G
Sbjct: 197 CKPSEMTSVTAWVLMHAFKLVGFPPGVVNMVIGEGKSAGQRLVDHVDVPLISFTGSTVIG 256
Query: 266 RHIMKTCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQ 325
+ I + A KKV+LE+GGK+P IV+ + + +IA F N GE+C SR++VQ
Sbjct: 257 KKIQEDGAKLNKKVSLEMGGKNPGIVYSNY-RKSDIASIARSSFLNQGEICLCTSRLFVQ 315
Query: 326 DTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGG 385
++ + ++ + + A+ VG+P + V GA S++ +K+ SY+++ EGA ++ GG
Sbjct: 316 KPIFADFVKSYVEEAKKFTVGDPTTQ-VQIGAMNSKVHYEKVKSYIELAKKEGADILCGG 374
Query: 386 ----ERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGL 441
+ GYFI PT+ + + +++ +EIFGPVV ++ F T +EV+ +AN + YGL
Sbjct: 375 VTTIQNGCENGYFITPTVIVGLHDASKVMTDEIFGPVVCITPFDTAEEVIERANSTPYGL 434
Query: 442 AAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQ 501
+A + + D ++ ++ +N ++AGTVW NT+ ++PFGG QSG GRE ++L Y+
Sbjct: 435 SATVWSSDSDELLNTANELRAGTVWCNTWLARDLSMPFGGCKQSGNGREGLHDSLHFYSD 494
Query: 502 TKAV 505
K V
Sbjct: 495 AKTV 498
>SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase
Length = 493
Score = 278 bits (710), Expect = 2e-74
Identities = 160/471 (33%), Positives = 258/471 (53%), Gaps = 5/471 (1%)
Query: 41 FINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAEPEDR 100
F+ G+++ S +KTFEV NP+ E I + + F + R
Sbjct: 21 FVQGKWISSPNNKTFEVDNPATGEIIGKVADVSVEETKKAISAANEAFKT-YKNFTHVQR 79
Query: 101 AKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGKVID 160
++ L + A+LI ++ + L + +L+NGK L + +V + YL+ A A + +G V
Sbjct: 80 SQLLERWAELIMENKDDLVKMLTLENGKPLSQAEMEVTTCSGYLKWYAAEAVRTFGDVAP 139
Query: 161 TG--ADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALY 218
+ + +F + ++P+GV I PWNFP M + K G ALA G T + PA TP L
Sbjct: 140 SSLQSQNFLISIKQPVGVSALITPWNFPAAMIARKGGAALAAGCTAIFLPAFRTPYVCLG 199
Query: 219 ACQLVQEAGVPKGVVNIIPGFGKIV-GERICTHPDIKKVAFTGSTATGRHIMKTCADSIK 277
+L QEAG P GV+N+I G+ + T+P ++KV+FTGST G+ +M A +IK
Sbjct: 200 LVRLAQEAGFPDGVLNVITSSDASAHGKELTTNPIVRKVSFTGSTNVGKILMGQSASTIK 259
Query: 278 KVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFK 337
KV++ELGG +P IVF D +D+AV++ F + G+VC +R+YV VY+E + K
Sbjct: 260 KVSMELGGNAPFIVFPDFPIDQAVESFCTIKFNSCGQVCVCPNRVYVHKNVYDEFVSKLT 319
Query: 338 QYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERI-GNKGYFIK 396
+ +++KVG+ F+ + G SQ K+ +++ S+GA++ GG+ I +KGYF +
Sbjct: 320 EKVKTIKVGDGFDSSSAVGPLISQDGCKKVSKHIEDAVSKGAKITVGGKEISSSKGYFFE 379
Query: 397 PTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAIDV 456
PT+ + V +DM + EE FGP+ +V KF +EV+ ANDS+ GLA + T +++ I V
Sbjct: 380 PTVLSGVTQDMLVASEETFGPLASVFKFDDTEEVIEWANDSDVGLAGYVFTNNLSTMIHV 439
Query: 457 SNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAVRM 507
+ ++ G V N + FGG QSG G+E G + + K + +
Sbjct: 440 AKELEVGLVGANIEMVDEPFISFGGIKQSGFGKEAGRLGVQEFMVVKEINL 490
>YBR006w [C] KOG2451 Aldehyde dehydrogenase
Length = 497
Score = 277 bits (709), Expect = 2e-74
Identities = 162/469 (34%), Positives = 254/469 (53%), Gaps = 6/469 (1%)
Query: 41 FINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAEPEDR 100
+I+G++V + FEV++P++ E I + E F + P +R
Sbjct: 22 YIDGKWVKGTD-EVFEVVDPASGEIIARVPEQPVSVVEEAIDVAYETFKT-YKNTTPRER 79
Query: 101 AKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGKVID 160
AK L + +L+ ++ + LA+I +L+NGK+L ++G++ A Y A A ++YG I
Sbjct: 80 AKWLRNMYNLMLENLDDLATIITLENGKALGEAKGEIKYAASYFEWYAEEAPRLYGATIQ 139
Query: 161 TGADHFS-YTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYA 219
H +T R+P+GVCG I PWNFP M + K ALA G TVV+KP TPLSAL
Sbjct: 140 PLNPHNRVFTIRQPVGVCGIICPWNFPSAMITRKAAAALAVGCTVVIKPDSQTPLSALAM 199
Query: 220 CQLVQEAGVPKGVVNIIPGFGKI--VGERICTHPDIKKVAFTGSTATGRHIMKTCADSIK 277
L ++AG PKG N+I +G+ +C P +KKV FTGST G+ +MK + ++K
Sbjct: 200 AYLAEKAGFPKGSFNVILSHANTPKLGKTLCESPKVKKVTFTGSTNVGKILMKQSSSTLK 259
Query: 278 KVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFK 337
K++ ELGG +P IVF DADLD+A++ F G+ C +R+YV ++ ++ +
Sbjct: 260 KLSFELGGNAPFIVFEDADLDQALEQAMACKFRGLGQTCVCANRLYVHSSIIDKFAKLLA 319
Query: 338 QYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKG-YFIK 396
+ + +G+ + G + I+K+ + +GA+V+ G R+ G F
Sbjct: 320 ERVKKFVIGHGLDPKTTHGCVINSSAIEKVERHKQDAIDKGAKVVLEGGRLTELGPNFYA 379
Query: 397 PTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAIDV 456
P I + V + KEE FGP+ + F T++EVV AND+E+GLAA + +K+VN V
Sbjct: 380 PVILSHVPSTAIVSKEETFGPLCPIFSFDTMEEVVGYANDTEFGLAAYVFSKNVNTLYTV 439
Query: 457 SNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAV 505
S ++ G V NT ++PFGG +SG GRE +++YT K +
Sbjct: 440 SEALETGMVSCNTGVFSDCSIPFGGVKESGFGREGSLYGIEDYTVLKTI 488
>CE10542 [C] KOG2451 Aldehyde dehydrogenase
Length = 569
Score = 261 bits (667), Expect = 2e-69
Identities = 162/496 (32%), Positives = 247/496 (49%), Gaps = 20/496 (4%)
Query: 10 LRRFIRLYSQLPLKVPVQLPNGITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHI 69
L +F R YS LP Q +I G++ S +F+VLNP N E +
Sbjct: 4 LSQFKRSYSLLP--------------QGAQAYIGGKWTASETGNSFDVLNPFNNEVVDRA 49
Query: 70 YEAREXXXXXXXXXXXXXFNNGWSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKS 129
F+ T + R L K +++ Q LA++ + + GK
Sbjct: 50 TNCTVKDAEKAVHSALEGFDKWAHTYSAKQRGAILHKWFEILVQRETELATLLTKEQGKP 109
Query: 130 LFCSRGDVALVAKYLRSCAGWADKIYGKVIDTGA-DHFSYTKREPLGVCGQIIPWNFPLL 188
L +RG++ A Y AG A ++YG+V+ + + REP+GV I PWNFP
Sbjct: 110 LAEARGEIQYSAAYFDWYAGEARRVYGQVVPSAVVNRLHLHTREPIGVVALIAPWNFPTA 169
Query: 189 MWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGE--- 245
M + K AL+ G + V+KP+ TPLSAL Q +EAG+P GV N+I E
Sbjct: 170 MIARKAAAALSVGCSAVVKPSGDTPLSALALAQTAEEAGIPAGVFNVITADHSNTAEISK 229
Query: 246 RICTHPDIKKVAFTGSTATGRHIMKTCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIA 305
+C D+ ++FTGST G+ ++ A ++K+V LELGG +P IVF DADLD AV
Sbjct: 230 YLCESTDVSAISFTGSTPVGKLLLAQSASTVKRVCLELGGNAPLIVFDDADLDVAVNGTM 289
Query: 306 FGIFYNSGEVCCAGSRIYVQDTVYEEVLEKF-KQYAESLKVGNPFEENVFQGAQTSQMQI 364
F SG+ C + +RIYV + ++++ + K E L +G+ QG +Q +
Sbjct: 290 ATKFRCSGQTCVSANRIYVHEKIHDQYISKLAAAMKEKLVLGDGLNPKTTQGPLVNQKAV 349
Query: 365 DKILSYVDVGTSEGARVITGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKF 424
DK + +G+ +I GG+R G G +PT+ +V+ + I EIFGP+ +V KF
Sbjct: 350 DKCELLLSDALGKGSELICGGKR-GEHGTSYEPTLITNVQSNTNIAHTEIFGPIASVQKF 408
Query: 425 TTVDEVVAKANDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQ 484
EV+ AN+ GLA + +D ++ V+ +++ G V +N FGG +
Sbjct: 409 RDEQEVLEAANNCRVGLAGYVFGRDQSRLQRVARKLEVGMVGVNEGLISCAEAAFGGVKE 468
Query: 485 SGIGREMGAEALDNYT 500
SGIGRE GA+ +D +T
Sbjct: 469 SGIGREGGAQGIDEFT 484
>Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 535
Score = 210 bits (534), Expect = 5e-54
Identities = 139/476 (29%), Positives = 233/476 (48%), Gaps = 15/476 (3%)
Query: 40 LFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAEPED 99
LFI G+FV S+ K ++ NP+ E I + +A + F W+
Sbjct: 42 LFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFP-AWADTSVLS 100
Query: 100 RAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGKVI 159
R + LL+ LI ++ + +A + +L+ GK+L + GDV + + + G+ +
Sbjct: 101 RQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMMGETM 160
Query: 160 DT-GADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALY 218
+ D Y+ R PLGVC I P+NFP ++ W A+ GNT ++KP+E P + +
Sbjct: 161 PSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATML 220
Query: 219 ACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIKK 278
+L+Q++G P G +NII G + V IC HPDIK ++F GS G +I + + K+
Sbjct: 221 LAKLLQDSGAPDGTLNIIHGQHEAV-NFICDHPDIKAISFVGSNKAGEYIFERGSRHGKR 279
Query: 279 VTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQ 338
V +G K+ +V DA+ + + + F +G+ C A S + ++ L + +
Sbjct: 280 VQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEA-KKWLPELVE 338
Query: 339 YAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGY----F 394
+A++L+V + G + +++ + +D GT EGA ++ G +I KGY F
Sbjct: 339 HAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGNF 398
Query: 395 IKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAI 454
+ PTI ++VK +M KEEIFGPV+ V + T+DE + N++ YG I T + A
Sbjct: 399 VGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATAR 458
Query: 455 DVSNRVKAGTVWINTYNNFHQNVPFGGFGQS-----GIGREMGAEALDNYTQTKAV 505
++ V G V +N +P F S G G + + YTQ K +
Sbjct: 459 KYAHLVDVGQVGVNV--PIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTI 512
>7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 552
Score = 208 bits (530), Expect = 1e-53
Identities = 143/481 (29%), Positives = 230/481 (47%), Gaps = 21/481 (4%)
Query: 38 TGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAEP 97
T LFI+G+FV S+ ++ +V +P+ + +T + +A + F + WS
Sbjct: 58 TKLFIDGKFVESKTNEWIDVHDPATNQVVTRVPKATQAEMQAALESNKKAFRS-WSNQSI 116
Query: 98 EDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGK 157
R + + KL LI ++ LA + + GK+L + GDV + + C G+
Sbjct: 117 LTRQQVMFKLQALIKENMGELAKNITKEQGKTLADAEGDVLRGLQVVEHCCSIPSLQMGE 176
Query: 158 VI-DTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSA 216
+ + D +Y+ PLGV + P+NFP ++ W A+ TGNT++LKP+E P +
Sbjct: 177 TVANVARDMDTYSLVLPLGVTAGVAPFNFPAMIPLWMFPVAITTGNTMLLKPSERVPGAT 236
Query: 217 LYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSI 276
+ +L+ EAG P GVVN+I G V IC P+IK V+F GS G++I + +
Sbjct: 237 MLLMELLNEAGCPPGVVNVIHGQHDAV-NFICDAPEIKAVSFVGSDQAGKYIYERAGKNG 295
Query: 277 KKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCA-GSRIYVQDTVYEEVLEK 335
K+V +G K+ I+ GDA+ + + +A F +G+ C A + ++V D + +
Sbjct: 296 KRVQSNMGAKNHGIILGDANKENTLNQLAGAAFGAAGQRCMALSTAVFVGDA--QAWIPD 353
Query: 336 FKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIG----NK 391
+ A+ LKV G S +I ++ G EGA++I G +I
Sbjct: 354 LVERAQKLKVNAGHVPGTDVGPVISAASRQRINDLIESGVKEGAKLILDGRKITVPGYED 413
Query: 392 GYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVN 451
GYF+ PTI +DV M+ EEIFGPV+ + K T+D+ + N + YG + T +
Sbjct: 414 GYFVGPTILSDVTPSMKCYTEEIFGPVLVILKADTLDDAIGIVNANPYGNGTAVFTTNGA 473
Query: 452 KAIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREM-------GAEALDNYTQTKA 504
A N + AG V +N VP F +G G + + YTQTK
Sbjct: 474 AARKFVNEIDAGQVGVNV----PIPVPLPMFSFTGTRGSFRGDHHFYGKQGIKFYTQTKT 529
Query: 505 V 505
V
Sbjct: 530 V 530
>CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 523
Score = 206 bits (524), Expect = 7e-53
Identities = 135/435 (31%), Positives = 219/435 (50%), Gaps = 10/435 (2%)
Query: 40 LFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAEPED 99
L+I+G+ V S+ E+ NP+ E I + A + FN W P
Sbjct: 32 LWIDGQAVESKTTDFVELTNPATNEVIAMVPNATQAEMQAAVDSAKNAFNT-WKNTSPLT 90
Query: 100 RAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGKVI 159
R +C+ KL LI + + LA +++ GK+L + GDV+ + + + G+ +
Sbjct: 91 RQQCMFKLQALIKRDMKKLAESITIEQGKTLPDAEGDVSRGLQVVEHACSVPSLMMGETL 150
Query: 160 -DTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALY 218
+ D +++ R PLGV I P+NFP ++ W ALATGNT+V+KP+E P +A
Sbjct: 151 PNVSRDMDTHSYRIPLGVTAGICPFNFPAMIPLWMFPVALATGNTMVIKPSEQDPGAAQL 210
Query: 219 ACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIKK 278
+L +EAGVP G VNII G V IC +PDIK ++F G A G+HI + A + K+
Sbjct: 211 LVELAKEAGVPDGCVNIIHGQHSAV-NFICDNPDIKAISFVGGDAAGKHIYERGAKNGKR 269
Query: 279 VTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCA-GSRIYVQDTVYEEVLEKFK 337
V +G K+ ++ DA+ ++ + + F +G+ C A + + V + L +
Sbjct: 270 VQSNMGAKNHGVIMADANKEQTLNQLTAAAFGAAGQRCMALTTAVLVGEA--RAWLPELV 327
Query: 338 QYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGY---- 393
+ A++LKV ++ + G S+ ++L ++ EGA+V G I G+
Sbjct: 328 EKAKNLKVNAGWKPDTDIGPLISKQSKARVLRLIESAKKEGAQVPLDGSNITVPGFENGN 387
Query: 394 FIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKA 453
F+ PTI A VK +M +EEIFGPV+ V + ++E + N++ YG I T + A
Sbjct: 388 FVGPTILAGVKPNMTCYREEIFGPVLVVMEAENLNEAIEIINNNPYGNGTAIFTSNGATA 447
Query: 454 IDVSNRVKAGTVWIN 468
+N V G + IN
Sbjct: 448 RKFTNEVDVGQIGIN 462
>At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 607
Score = 202 bits (514), Expect = 1e-51
Identities = 148/496 (29%), Positives = 233/496 (46%), Gaps = 31/496 (6%)
Query: 23 KVPVQLPNGITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXX 82
++P ++PN I G FV S+ +V+NP+ +E ++ +
Sbjct: 109 QMPPRVPN----------LIGGSFVESQSSSFIDVINPATQEVVSKVPLTTNEEFKAAVS 158
Query: 83 XXXXXFNNGWSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAK 142
F W R + +LK +LI ++ + LA + + GK+L S GD+ +
Sbjct: 159 AAKQAFPL-WRNTPITTRQRVMLKFQELIRKNMDKLAMNITTEQGKTLKDSHGDIFRGLE 217
Query: 143 YLRSCAGWADKIYGKV---IDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALA 199
+ G A G+ + G D +Y+ REPLGVC I P+NFP ++ W A+
Sbjct: 218 VVEHACGMATLQMGEYLPNVSNGVD--TYSIREPLGVCAGICPFNFPAMIPLWMFPVAVT 275
Query: 200 TGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFT 259
GNT +LKP+E P +++ +L EAG+P GV+NI+ G V IC DI+ V+F
Sbjct: 276 CGNTFILKPSEKDPGASVILAELAMEAGLPDGVLNIVHGTNDTV-NAICDDEDIRAVSFV 334
Query: 260 GSTATGRHIMKTCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAG 319
GS G HI A K++ +G K+ +V DA++D + + F +G+ C A
Sbjct: 335 GSNTAGMHIYARAAAKGKRIQSNMGAKNHGLVLPDANIDATLNALLAAGFGAAGQRCMAL 394
Query: 320 SR-IYVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEG 378
S ++V D E +K + A++LKV E + G S+ ++I + G +G
Sbjct: 395 STVVFVGDAKSWE--DKLVERAKALKVTCGSEPDADLGPVISKQAKERICRLIQSGVDDG 452
Query: 379 ARVITGGERI----GNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKA 434
A+++ G I KG FI PTI + V DM+ KEEIFGPV+ + + DE ++
Sbjct: 453 AKLLLDGRDIVVPGYEKGNFIGPTILSGVTPDMECYKEEIFGPVLVCMQANSFDEAISII 512
Query: 435 NDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVPFGGF-----GQSGIGR 489
N ++YG A I T A ++AG + IN +PF F +G
Sbjct: 513 NKNKYGNGAAIFTSSGAAARKFQMDIEAGQIGINV--PIPVPLPFFSFTGNKASFAGDLN 570
Query: 490 EMGAEALDNYTQTKAV 505
G +D +TQ K V
Sbjct: 571 FYGKAGVDFFTQIKTV 586
>At2g24270 [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 193 bits (490), Expect = 6e-49
Identities = 149/483 (30%), Positives = 230/483 (46%), Gaps = 17/483 (3%)
Query: 41 FINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAEPEDR 100
+ +GE+ S K+ ++NP+ + + + W+ R
Sbjct: 19 YADGEWKTSSSGKSVAIMNPATRKTQYKVQACTQEEVNAVMELAKSA-QKSWAKTPLWKR 77
Query: 101 AKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGK--- 157
A+ L K A ++ + +A + K S +V + CA +I G+
Sbjct: 78 AELLHKAAAILKDNKAPMAESLVKEIAKPAKDSVTEVVRSGDLISYCAEEGVRILGEGKF 137
Query: 158 -VIDT--GADHFSY--TKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEAT 212
+ D+ G D Y T + PLGV I P+N+P+ + K+ PAL GN++VLKP
Sbjct: 138 LLSDSFPGNDRTKYCLTSKIPLGVVLAIPPFNYPVNLAVSKIAPALIAGNSLVLKPPTQG 197
Query: 213 PLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTC 272
+S L+ AG PKG+++ I G G +G+ + HP + ++FTG TG I K
Sbjct: 198 AVSCLHMVHCFHLAGFPKGLISCITGKGSEIGDFLTMHPAVNCISFTGGD-TGISISKKA 256
Query: 273 ADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEV 332
+ + +ELGGK IV DADLD NI G F SG+ C A + V ++V +E+
Sbjct: 257 --GMIPLQMELGGKDACIVLDDADLDLVASNIIKGGFSYSGQRCTAVKVVLVMESVADEL 314
Query: 333 LEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKG 392
+EK K L VG P EEN A S+ + I V +GA +R GN
Sbjct: 315 VEKVKAKVAKLTVGPP-EENSDITAVVSESSANFIEGLVMDAKEKGATFCQEYKREGN-- 371
Query: 393 YFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNK 452
I P + +V+ DM+I EE FGPVV V + +V+E + N S +GL + TKD+NK
Sbjct: 372 -LIWPLLLDNVRPDMRIAWEEPFGPVVPVLRINSVEEGINHCNASNFGLQGCVFTKDINK 430
Query: 453 AIDVSNRVKAGTVWINTY-NNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAVRMAIDH 511
AI +S+ ++ GTV IN+ + PF G SGIG + +++ T+ K + +
Sbjct: 431 AILISDAMETGTVQINSAPARGPDHFPFQGLKDSGIGSQGVTNSINLMTKVKTTVINLPT 490
Query: 512 PNY 514
P+Y
Sbjct: 491 PSY 493
>At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 578
Score = 190 bits (483), Expect = 4e-48
Identities = 126/430 (29%), Positives = 213/430 (49%), Gaps = 20/430 (4%)
Query: 92 WSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLF-CSRGDVALVAKYLRSCAGW 150
W+ + + R + L L I +H E + + S D GK++ S G++ + +
Sbjct: 102 WAQSSFKLRRQFLRILLKYIIEHQELICEVSSRDTGKTMVDASLGEIMTTCEKITWLLSE 161
Query: 151 ADK-IYGKVIDTGADHFSYTKR---EPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVL 206
++ + + +G R PLGV G I+PWN+P + A+ +GN +V+
Sbjct: 162 GERWLKPESRSSGRAMLHKVSRVEFHPLGVIGAIVPWNYPFHNIFNPMLAAVFSGNGIVI 221
Query: 207 KPAEATPLSALYACQLVQEA----GVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGST 262
K +E S + +++Q A G P+ +V++I GF + GE + + D K+ F GST
Sbjct: 222 KVSEHASWSGCFYFRIIQAALAAVGAPENLVDVITGFAE-TGEALVSSVD--KMIFVGST 278
Query: 263 ATGRHIMKTCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRI 322
A G+ IM+ A+++ VTLELGGK I+ DAD+ + G +SG+ C R
Sbjct: 279 AVGKMIMRNAAETLTPVTLELGGKDAFIICEDADVSHVAQVAVRGTLQSSGQNCAGAERF 338
Query: 323 YVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVI 382
YV +Y + + + +S+ G P GA Q + + S V+ +GA +
Sbjct: 339 YVHKDIYTAFIGQVTKIVKSVSAGPPLTGRYDMGAICLQEHSEHLQSLVNDALDKGAEIA 398
Query: 383 TGGERIGNKG-----YFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDS 437
G G+ G + PT+ +V +M+I+KEE FGP++ + +F+T +EV+ ANDS
Sbjct: 399 VRGS-FGHLGEDAVDQYFPPTVLINVNHNMKIMKEEAFGPIMPIMQFSTDEEVIKLANDS 457
Query: 438 EYGLAAGIHTKDVNKAIDVSNRVKAGTVWINTY--NNFHQNVPFGGFGQSGIGREMGAEA 495
Y L + + ++A ++++++ G IN + N Q++PFGG SG GR G E
Sbjct: 458 RYALGCAVFSGSKHRAKQIASQIQCGVAAINDFASNYMCQSLPFGGVKDSGFGRFAGIEG 517
Query: 496 LDNYTQTKAV 505
L K+V
Sbjct: 518 LRACCLVKSV 527
>CE01232 [C] KOG2453 Aldehyde dehydrogenase
Length = 514
Score = 184 bits (468), Expect = 2e-46
Identities = 138/488 (28%), Positives = 230/488 (46%), Gaps = 34/488 (6%)
Query: 31 GITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNN 90
G+T E G+F +G++ S Q + P+N I ++ +N+
Sbjct: 19 GLT-ENNAGVF-HGKWAASGQ--VVQSFAPANNSPIANVQNGNVQDYEIAISEAKKAYND 74
Query: 91 GWSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAKYLRSC--- 147
W R + + ++ D + + L + SL+ GK S V V +Y+ C
Sbjct: 75 -WCEVPAPRRGEIVRQIGDKLRTQLQNLGKLVSLEMGK---ISAEGVGEVQEYVDICDYA 130
Query: 148 AGWADKIYGKVIDTGAD-HFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVL 206
G + + GK+ + H + PLGV G I +NFP ++ W AL TGN+VV
Sbjct: 131 TGLSRSLEGKIFPSERPGHALLEQWNPLGVVGVISAFNFPCAVYGWNNALALVTGNSVVW 190
Query: 207 KPAEATPLSALYACQLVQEAGVPKGV----VNIIPGFGKIVGERICTHPDIKKVAFTGST 262
KPA +TPL+A+ +LV+E V V +++ G G VG+ + + V+FTGS+
Sbjct: 191 KPAPSTPLTAIAVTKLVEEVLVANNVNPALCSLVCGEGD-VGQALVKDKRVNLVSFTGSS 249
Query: 263 ATGRHIMKTCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRI 322
G+ + + K+ LELGG + IV DADL+ V F +G+ C R+
Sbjct: 250 EIGKIVGQQVQARFGKLLLELGGNNAIIVNEDADLNMVVPATVFAAVGTAGQRCTTTRRL 309
Query: 323 YVQDTVYEEVLEKFKQ-YAE-SLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGAR 380
V D VY++VLE+ K+ YA+ ++G P + N G +Q + K + V + G +
Sbjct: 310 IVHDKVYDQVLERLKKAYAQFESRIGCPLDSNTIIGPLHNQQAVGKYKASVAEAVASGGK 369
Query: 381 VITGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYG 440
+ GG+ + G F+ PTI +K D +V E F P++ V KF+T++E +A N+ + G
Sbjct: 370 IEYGGKVLERDGNFVLPTIVTGLKHDSPVVLRETFAPILYVLKFSTLEEAIAINNEVDQG 429
Query: 441 LAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNVP---------FGGFGQSGIGREM 491
L++ + T ++ + +N N+P FGG ++G GRE
Sbjct: 430 LSSSLFTTNIQNVFKWMGPKGSDCGIVNV------NIPTSGAEIGGAFGGEKETGGGRES 483
Query: 492 GAEALDNY 499
G+++ Y
Sbjct: 484 GSDSWRQY 491
>At1g54100 [C] KOG2453 Aldehyde dehydrogenase
Length = 508
Score = 180 bits (456), Expect = 5e-45
Identities = 130/450 (28%), Positives = 206/450 (44%), Gaps = 11/450 (2%)
Query: 58 LNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAEPEDRAKCLLKLADLIDQHAET 117
LNP+N + I + EA W R + ++ D + +
Sbjct: 39 LNPANNQPIAQVVEASLEDYEQGLKACEEAAKI-WMQVTAPKRGDIVRQIGDALRSKLDY 97
Query: 118 LASIESLDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGKVIDTGA-DHFSYTKREPLGV 176
L + SL+ GK L G+V V G + ++ G VI + +H PLG+
Sbjct: 98 LGRLLSLEMGKILAEGIGEVQEVIDMCDFAVGLSRQLNGSVIPSERPNHMMLEMWNPLGI 157
Query: 177 CGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEA----GVPKGV 232
G I +NFP + W AL GN VV K A TPL + +LV E +P +
Sbjct: 158 VGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAMTKLVAEVLEKNNLPGAI 217
Query: 233 VNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIKKVTLELGGKSPNIVF 292
+ G G +GE I I V+FTGS+ G + +T K LEL G + IV
Sbjct: 218 FTAMCG-GAEIGEAIAKDTRIPLVSFTGSSRVGSMVQQTVNARSGKTLLELSGNNAIIVM 276
Query: 293 GDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQYAESLKVGNPFEEN 352
DAD+ A +++ F +G+ C R+ + ++VY++VLE+ + +K+GNP E+
Sbjct: 277 DDADIQLAARSVLFAAVGTAGQRCTTCRRLLLHESVYDKVLEQLLTSYKQVKIGNPLEKG 336
Query: 353 VFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGYFIKPTIFADVKEDMQIVKE 412
G + ++V S+G +++TGG+ + +G F++PTI ++ D +VKE
Sbjct: 337 TLLGPLHTPESKKNFEKGIEVIKSQGGKILTGGKAVEGEGNFVEPTII-EISADAAVVKE 395
Query: 413 EIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAIDVSNRV--KAGTVWINTY 470
E+F PV+ V KF + E VA N GL++ I T++ + G V +N
Sbjct: 396 ELFAPVLYVLKFKSFGEAVAINNSVPQGLSSSIFTRNPENIFRWIGPLGSDCGIVNVNIP 455
Query: 471 NNFHQ-NVPFGGFGQSGIGREMGAEALDNY 499
N + FGG +G GRE G+++ Y
Sbjct: 456 TNGAEIGGAFGGEKATGGGREAGSDSWKQY 485
>SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 522
Score = 172 bits (436), Expect = 1e-42
Identities = 117/428 (27%), Positives = 202/428 (46%), Gaps = 15/428 (3%)
Query: 92 WSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLF-CSRGDVALVAKYLRSCAGW 150
W + +R L L + I ++ + A I D GK+L + G++ + + +
Sbjct: 41 WKSTSFAERRNFLKALKENIIRNQDKYAEIACKDTGKTLVDAAFGEILVTLEKINWTLAN 100
Query: 151 ADKIYGKVIDTGADHFS----YTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVL 206
++ + S Y K EPLGV ++ WN+PL + AL GN +V+
Sbjct: 101 GEQSLRPTKRPNSLLTSYKGGYVKYEPLGVIAALVSWNYPLHNALGPIISALFAGNAIVV 160
Query: 207 KPAEATPLSALYACQLV----QEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGST 262
K +E T S C++V Q G +V I V + + +H IK + F GS
Sbjct: 161 KGSELTAWSTHQYCEMVRSLLQSMGHSPELVQCITCLPD-VADHLTSHSGIKHITFIGSQ 219
Query: 263 ATGRHIMKTCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRI 322
+ + + A + + LELGGK P I+ D L++ + + G+F ++G+ C RI
Sbjct: 220 PIAKLVAASAAKQLTPLCLELGGKDPCILTDDHRLEEILSIVMRGVFQSAGQNCIGIERI 279
Query: 323 YVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVI 382
D VY+ ++ K ++++G + +V GA S + D + S + S+GAR++
Sbjct: 280 IALDGVYDTIITKLYNRISTMRLGMYTQNDVDMGAMVSNNRFDHLESLIQDAVSKGARLV 339
Query: 383 TGGERIGN----KGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSE 438
GG R + KG + PT+ D +M+I +EE F P+ V + + + + AN +E
Sbjct: 340 YGGHRFQHPKYPKGNYFLPTLLVDATNEMKIAQEECFAPIALVFRAKSPEHALEIANGTE 399
Query: 439 YGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFH-QNVPFGGFGQSGIGREMGAEALD 497
+GL A + +D ++ ++ G V +N + F+ +PFGG +SG GR G E L
Sbjct: 400 FGLGASVFGRDKQLCQYFTDNLETGMVAVNDFGAFYLLQMPFGGCKKSGYGRFAGYEGLR 459
Query: 498 NYTQTKAV 505
+KA+
Sbjct: 460 GICNSKAI 467
>Hs4557343 [C] KOG2453 Aldehyde dehydrogenase
Length = 511
Score = 172 bits (436), Expect = 1e-42
Identities = 114/448 (25%), Positives = 208/448 (45%), Gaps = 10/448 (2%)
Query: 60 PSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAEPEDRAKCLLKLADLIDQHAETLA 119
P+N E I + +A + W+ R + + ++ D + + + L
Sbjct: 43 PANNEPIARVRQASVADYEETVKKAREAWKI-WADIPAPKRGEIVRQIGDALREKIQVLG 101
Query: 120 SIESLDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGKVIDTG-ADHFSYTKREPLGVCG 178
S+ SL+ GK L G+V G + I G ++ + + H + P+G+ G
Sbjct: 102 SLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVG 161
Query: 179 QIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLV----QEAGVPKGVVN 234
I +NFP+ ++ W A+ GN + K A T L ++ +++ ++ +P + +
Sbjct: 162 IITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICS 221
Query: 235 IIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIKKVTLELGGKSPNIVFGD 294
+ G G +G + + ++FTGST G+ + + + LELGG + I F D
Sbjct: 222 LTCG-GADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFED 280
Query: 295 ADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQYAESLKVGNPFEENVF 354
ADL V + F +G+ C R+++ +++++EV+ + K+ ++VGNP++ NV
Sbjct: 281 ADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVL 340
Query: 355 QGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGYFIKPTIFADVKEDMQIVKEEI 414
G ++ + L V+ EG V+ GG+ + G +++PTI + D I E
Sbjct: 341 YGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTET 400
Query: 415 FGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAID--VSNRVKAGTVWINTYNN 472
F P++ V KF +EV A N+ + GL++ I TKD+ + G V +N +
Sbjct: 401 FAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTS 460
Query: 473 FHQ-NVPFGGFGQSGIGREMGAEALDNY 499
+ FGG +G GRE G++A Y
Sbjct: 461 GAEIGGAFGGEKHTGGGRESGSDAWKQY 488
>YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G
Length = 644
Score = 170 bits (431), Expect = 4e-42
Identities = 119/440 (27%), Positives = 207/440 (47%), Gaps = 26/440 (5%)
Query: 92 WSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLF-CSRGDVALVAKYLRSCAGW 150
W ++ R + L L D I + + +A + D+GK++ S G++ + + ++
Sbjct: 148 WGNSDFSRRLRVLASLHDYILNNQDLIARVACRDSGKTMLDASMGEILVTLEKIQWTIKH 207
Query: 151 ADKIYGKVIDTGADHF-------SYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNT 203
+ G +F + + EPLGV I+ WN+P + AL TGN
Sbjct: 208 GQRALQPSRRPGPTNFFMKWYKGAEIRYEPLGVISSIVSWNYPFHNLLGPIIAALFTGNA 267
Query: 204 VVLKPAEATPLSALYACQLV--------QEAGVPKGVVNIIPGFGKIVGERICTHPDIKK 255
+V+K +E S+ + +L+ ++ + + + P +HP K
Sbjct: 268 IVVKCSEQVVWSSEFFVELIRKCLEACDEDPDLVQLCYCLPPTENDDSANYFTSHPGFKH 327
Query: 256 VAFTGSTATGRHIMKTCADSIKKVTLELGGKSPNIVFGDA-DLDKAVKNIAFGIFYNSGE 314
+ F GS +I+K A S+ V +ELGGK IV A +LD I G F +SG+
Sbjct: 328 ITFIGSQPVAHYILKCAAKSLTPVVVELGGKDAFIVLDSAKNLDALSSIIMRGTFQSSGQ 387
Query: 315 VCCAGSRIYVQDTVYEEVLEKF--KQYAESLKVGNPFE--ENVFQGAQTSQMQIDKILSY 370
C R+ V Y+++++ + A L+ G+ + ENV GA S + D++ +
Sbjct: 388 NCIGIERVIVSKENYDDLVKILNDRMTANPLRQGSDIDHLENVDMGAMISDNRFDELEAL 447
Query: 371 VDVGTSEGARVITGGERIGN----KGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTT 426
V ++GAR++ GG R + +G++ +PT+ DV +M+I + E+FGP++ + K
Sbjct: 448 VKDAVAKGARLLQGGSRFKHPKYPQGHYFQPTLLVDVTPEMKIAQNEVFGPILVMMKAKN 507
Query: 427 VDEVVAKANDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQ-NVPFGGFGQS 485
D V AN + +GL + D+ + V+N ++ G V IN + F+ +PFGG S
Sbjct: 508 TDHCVQLANSAPFGLGGSVFGADIKECNYVANSLQTGNVAINDFATFYVCQLPFGGINGS 567
Query: 486 GIGREMGAEALDNYTQTKAV 505
G G+ G E L K+V
Sbjct: 568 GYGKFGGEEGLLGLCNAKSV 587
>7293810 [C] KOG2453 Aldehyde dehydrogenase
Length = 594
Score = 169 bits (427), Expect = 1e-41
Identities = 125/432 (28%), Positives = 204/432 (46%), Gaps = 18/432 (4%)
Query: 92 WSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAKYLRSCAGWA 151
W R + + ++ D + ++ E L + SL+ GK +G+V G +
Sbjct: 154 WRQVPAPVRGEIVRQIGDELRKYKEPLGKLVSLEVGKIYSEGQGEVQEFIDICDYAVGLS 213
Query: 152 DKIYGKVIDTG-ADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAE 210
G++I++ ADH PLGV G I +NFP ++ W AL TGN+V+ K A
Sbjct: 214 RIYSGQLINSERADHSILEAWRPLGVVGVISAYNFPNAVFGWNAAIALTTGNSVLWKGAP 273
Query: 211 ATPLSALYACQLVQEA----GVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGR 266
+TPL ++ ++V E +P VV + G G VG+ + + V+FTGS TGR
Sbjct: 274 STPLVSVATTKIVAEVLRRNNLPP-VVTLCQG-GTDVGQTLVADKRVNLVSFTGSCQTGR 331
Query: 267 HIMKTCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQD 326
+ KV LELGG + I+ A++ A+ FG SG+ C RI V +
Sbjct: 332 DVGVEVQRRFGKVILELGGNNALIIDESANVKMALDAALFGCIGTSGQRCTTTRRIIVHE 391
Query: 327 TVYE----EVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVI 382
+++ E++ K+KQ K+G+ E G +Q ++ + + S G V
Sbjct: 392 KLHDQFVKELVGKYKQLIS--KIGHQLEAQTLVGPVHTQQNVENYKAAIAEAKSLGGTVA 449
Query: 383 TGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLA 442
GG I G++++PT+ + D +V E F P+V + K VD+ + N+ E GL+
Sbjct: 450 FGGNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILKAKNVDQAIEWNNEVEQGLS 509
Query: 443 AGIHTKDVNKAID--VSNRVKAGTVWINTYNNFHQ-NVPFGGFGQSGIGREMGAEALDNY 499
+ I T+++ +A + G V INT N + FGG +G GRE G++A Y
Sbjct: 510 SAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFGGEKATGGGRESGSDAWKQY 569
Query: 500 TQTKAVRMAIDH 511
K + ++H
Sbjct: 570 --CKRATITVNH 579
>CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 157 bits (398), Expect = 3e-38
Identities = 122/420 (29%), Positives = 208/420 (49%), Gaps = 21/420 (5%)
Query: 92 WSTAEPEDRAKCLLKLADLI-DQHAETLASIESLDNGKSLFCSRGDVAL-VAKYLRSCAG 149
W ++RA+ LL+ ADL ++ L + L GK++ + D A + + R A
Sbjct: 116 WERKPLKERAEILLRAADLAAGKYRMKLNASTMLGQGKNIIQAEIDAACELIDFFRFNAV 175
Query: 150 WADKI-YGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKP 208
+A ++ + + I T + R G I P+NF + + PAL GN + KP
Sbjct: 176 FAMELEHYEPISTKITKNTMQFRGMEGFVAAIAPFNFTAIGGNLPTAPALM-GNVSLWKP 234
Query: 209 AEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHI 268
+ LS +L++EAG+P G+++ +P G + G+ I P + V FTGS T + I
Sbjct: 235 SNTAVLSNYIIYELLEEAGMPPGILSFLPSDGPVFGDVITASPHLSAVNFTGSVPTFKTI 294
Query: 269 MKTCADSI------KKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRI 322
+ A+++ K+ E GGK+ + V A +D A + SG+ C A SR+
Sbjct: 295 WRKVAENLDNYVTFPKLIGECGGKNFHFVHPSAHVDAVAAGTARSAWEYSGQKCSACSRM 354
Query: 323 YVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGT--SEGAR 380
Y +++ ++LEK + +K+G+ + +VF A ++ +Y+D ++GA
Sbjct: 355 YAPKSIWPKILEKISAIHKEIKLGDVRDGSVFLSAVIDDKAFARLKAYIDFAKTGADGAN 414
Query: 381 VITGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKF--TTVDEVVAKAND-S 437
V+ GG+ GYFI+PT+ +++ EE+FGPVVTV + + VDEV+A D +
Sbjct: 415 VVLGGKCDDKTGYFIEPTLITVTDPKSKLLTEEMFGPVVTVLVYEDSKVDEVLATVKDAT 474
Query: 438 EYGLAAGIHTKD---VNKAIDVSNRVKAGTVWIN--TYNNFHQNVPFGGFGQSGIGREMG 492
YGL + ++D + +A DV R G +++N + + PFGG SG + G
Sbjct: 475 PYGLTGAVFSQDKEFLYRARDVL-RDAVGNMYLNDKSTGSIVGQQPFGGSRLSGTNDKAG 533
>CE13415 [C] KOG2456 Aldehyde dehydrogenase
Length = 437
Score = 154 bits (390), Expect = 2e-37
Identities = 128/430 (29%), Positives = 200/430 (45%), Gaps = 24/430 (5%)
Query: 88 FNNGWSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSR-----GDVALVAK 142
FN G +T E R + LL+L LI+++ L + D + + G + +A
Sbjct: 14 FNTG-ATKPAEFRKEQLLQLKKLIEENRAALTEVVWKDLRRRHEVTEPMELGGSLEEIAY 72
Query: 143 YLRSCAGWADKIYGK-VIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATG 201
YL++ W Y + + T Y ++P GV I PWN+P+ M + P++A G
Sbjct: 73 YLKNLDDWMKPTYVEPTVATLPTDKPYIVKDPKGVVLVISPWNYPVSMVLLPMIPSIAAG 132
Query: 202 NTVVLKPAEATPLSALYACQLVQEAGVPKGVVNI---IPGFGKIVGERICTHPDIKKVAF 258
NT+V+KP+E + +A+ +L+ + PK V + IP +++ ER + +
Sbjct: 133 NTIVIKPSELSENTAILFEKLIPKYFDPKYVTIVNGGIPETTELLKERF------DHIIY 186
Query: 259 TGSTATGRHIMKTCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCA 318
TG + IM A + VTLELGGK P +V DAD++ + + IA G + N G+ C A
Sbjct: 187 TGCPPVAKIIMAAAAKHLTPVTLELGGKCPVVVEDDADIEISAQRIARGKWLNCGQTCLA 246
Query: 319 GSRIYVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEG 378
I V + + ++ + GN E + +Q D+I + +D S+G
Sbjct: 247 PDYILVSSATKPKFVAAIQKCLKEFYGGNAKESKDYSRV-INQRHFDRISALLD--ESKG 303
Query: 379 ARVITGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSE 438
+ E FI PT+ DV++ + +EIFGPV+ + + E + N E
Sbjct: 304 VVLAGNEESRDRSDRFIPPTVL-DVEKTDPFMHDEIFGPVLPIITVKNLCESIDFINKGE 362
Query: 439 YGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNFHQNV---PFGGFGQSGIGREMGAEA 495
LAA I TKD K N +G V +N H V PFGG G SG+GR G
Sbjct: 363 KPLAAYIFTKDEAKVQRFLNETTSGGVTVNDV-IMHVAVITLPFGGVGVSGMGRYRGKFG 421
Query: 496 LDNYTQTKAV 505
D +T K+V
Sbjct: 422 FDTFTHEKSV 431
>CE27441 [C] KOG2456 Aldehyde dehydrogenase
Length = 493
Score = 154 bits (389), Expect = 3e-37
Identities = 126/423 (29%), Positives = 199/423 (46%), Gaps = 36/423 (8%)
Query: 100 RAKCLLKLADLIDQHAETLA------------SIESLDNGKSLFCSRGDVALVAKYLRSC 147
R + LLKL I+++ E L+ S E L+ G + + + +L++
Sbjct: 25 RKQQLLKLKKFIEENREALSEAVWKDLRRRHESTEILEIGMT-------IQEIDYFLKNI 77
Query: 148 AGWADKIYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLK 207
W + + T A +++P GV I PWN+P+ M + PA+A GNTVV+K
Sbjct: 78 DDWVKPTHVEKTFTTALDKPVIEKDPKGVVLIISPWNYPVSMILLPMVPAIAAGNTVVIK 137
Query: 208 PAEATPLSALYACQLVQEAGVPKGVVNI---IPGFGKIVGERICTHPDIKKVAFTGSTAT 264
P+E + A +L+ + K V + IP ++ ER + +TG
Sbjct: 138 PSELSENVAATFEKLIPKYFESKYVTVVNGGIPETTDLLKERF------DHILYTGCPPV 191
Query: 265 GRHIMKTCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYV 324
+ IM A + VTLELGGK P +V DAD+D + K IA+G + N G+ C A I V
Sbjct: 192 AKIIMTAAAKHLTPVTLELGGKCPVVVEDDADIDISAKRIAWGKWLNCGQTCLAPDYILV 251
Query: 325 QDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITG 384
TV +++ ++Y G + + +Q D+I +D ++GA V+ G
Sbjct: 252 NSTVKPKLVAAIRKYVNEF-YGEDVKASKDYARMINQRHFDRISGLLD--KTQGA-VLIG 307
Query: 385 GERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAG 444
GER +I PT+ DV++ + +EIFGPV+ + + E + D E LAA
Sbjct: 308 GER-DRADLYIPPTVL-DVEKSDPFMHDEIFGPVLPIITVQSFSESLEYIADGEKPLAAY 365
Query: 445 IHTKDVNKAIDVSNRVKAGTVWIN--TYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQT 502
I T++ K + N +G V +N + +PFGG G SG+GR G D +T
Sbjct: 366 IFTRNEAKVKRLLNETSSGGVTVNDVLMHITVDTLPFGGVGVSGMGRYRGKYGFDTFTHE 425
Query: 503 KAV 505
K+V
Sbjct: 426 KSV 428
>Hs20546780 [C] KOG2450 Aldehyde dehydrogenase
Length = 637
Score = 144 bits (363), Expect = 3e-34
Identities = 96/326 (29%), Positives = 168/326 (51%), Gaps = 7/326 (2%)
Query: 174 LGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVV 233
+GV G I+P F L W++ PALA G TVV A+P L A QL E G G++
Sbjct: 1 MGVIGLILPPTFSFLEMMWRICPALAVGCTVVALVPPASPAPLLLA-QLAGELGPFPGIL 59
Query: 234 NIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIKKVTLELGGKSPNIVFG 293
N++ G +V + + P I+KVAF G+ GR + ++ A ++ L LG +S ++
Sbjct: 60 NVLSGPASLV-PILASQPGIRKVAFCGAPEEGRALRRSLAGECAELGLALGTESLLLLTD 118
Query: 294 DADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQYAESLKVGNPFEENV 353
AD+D AV+ + + + G G R+ +Q++V++E + + ++ L+ G + V
Sbjct: 119 TADVDSAVEGVVDAAWSDRGP---GGLRLLIQESVWDEAMRRLQERMGRLRSGRGLDGAV 175
Query: 354 FQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGYFIKPTIFADVKEDMQIVKEE 413
GA+ + D + +V S+GA+V G+ + ++ F PT+ +++ + E
Sbjct: 176 DMGARGAAA-CDLVQRFVREAQSQGAQVFQAGD-VPSERPFYPPTLVSNLPPASPCAQVE 233
Query: 414 IFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWINTYNNF 473
+ PVV S F T E + AN + G +A + ++ + +A+++ ++ GTVWIN +
Sbjct: 234 VPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLGQALELGYGLQVGTVWINAHGLR 293
Query: 474 HQNVPFGGFGQSGIGREMGAEALDNY 499
+VP GG +SG G + L Y
Sbjct: 294 DPSVPTGGCKESGCSWHGGPDGLYEY 319
Score = 82.4 bits (202), Expect = 1e-15
Identities = 76/275 (27%), Positives = 114/275 (40%), Gaps = 14/275 (5%)
Query: 17 YSQLPLKVPVQLPNGITY----EQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEA 72
Y L VP LP G P GLF+ G F + + + S ++ E
Sbjct: 338 YDTFGLAVPSTLPAGPEIGPSPAPPYGLFVGGRFQAPGARSSRPIRDSSGNLH-GYVAEG 396
Query: 73 REXXXXXXXXXXXXXFNNGWSTAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLFC 132
F GW+ P RA L LA +++ TLAS G L
Sbjct: 397 GAKDIRGAVEAAHQAFP-GWAGQSPGARAALLWALAAALERRKSTLAS-RLERQGAELKA 454
Query: 133 SRGDVALVAKYLRSCAGWADKIY--GKVIDTGADHFSYTK-REPLGVCGQIIPWNFPLLM 189
+ +V L A+ LR+ W ++ G + + REPLGV + P +PLL
Sbjct: 455 AEAEVELSARRLRA---WGARVQAQGHTLQVAGLRGPVLRLREPLGVLAVVCPDEWPLLA 511
Query: 190 WSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICT 249
+ + PALA GNTVV+ P+ A PL AL CQ + P G+ N++ G + +
Sbjct: 512 FVSLLAPALAYGNTVVMVPSAACPLLALEVCQDMATV-FPAGLANVVTGDRDHLTRCLAL 570
Query: 250 HPDIKKVAFTGSTATGRHIMKTCADSIKKVTLELG 284
H D++ + + GS + + A ++K V G
Sbjct: 571 HQDVQAMWYFGSAQGSQFVEWASAGNLKPVWASRG 605
>HsM4502035 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 140 bits (352), Expect = 6e-33
Identities = 108/357 (30%), Positives = 169/357 (47%), Gaps = 15/357 (4%)
Query: 151 ADKIYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAE 210
AD+ K T D Y EPLGV I WN+P + + A+A GN VVLKP+E
Sbjct: 83 ADEPVEKTPQTQQDEL-YIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSE 141
Query: 211 ATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMK 270
+ A ++ + + K + +I G E + D + +TGST G+ IM
Sbjct: 142 LSENMASLLATIIPQY-LDKDLYPVINGGVPETTELLKERFD--HILYTGSTGVGKIIMT 198
Query: 271 TCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYE 330
A + VTLELGGKSP V + DLD A + IA+G F NSG+ C A I ++
Sbjct: 199 AAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQN 258
Query: 331 EVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGN 390
+++EK K+ + G +++ G S +++ G EG +V GG
Sbjct: 259 QIVEKLKKSLKEF-YGEDAKKSRDYGRIISARHFQRVM-----GLIEGQKVAYGGTGDAA 312
Query: 391 KGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDV 450
Y I PTI DV +++EEIFGPV+ + +++E + N E LA + + +
Sbjct: 313 TRY-IAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSND 371
Query: 451 NKAIDVSNRVKAGTVWIN---TYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKA 504
+ +G V N + H ++PFGG G SG+G G ++ + ++ ++
Sbjct: 372 KVIKKMIAETSSGGVAANDVIVHITLH-SLPFGGVGNSGMGSYHGKKSFETFSHRRS 427
>Hs21359829 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 140 bits (352), Expect = 6e-33
Identities = 108/357 (30%), Positives = 169/357 (47%), Gaps = 15/357 (4%)
Query: 151 ADKIYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAE 210
AD+ K T D Y EPLGV I WN+P + + A+A GN VVLKP+E
Sbjct: 83 ADEPVEKTPQTQQDEL-YIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSE 141
Query: 211 ATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMK 270
+ A ++ + + K + +I G E + D + +TGST G+ IM
Sbjct: 142 LSENMASLLATIIPQY-LDKDLYPVINGGVPETTELLKERFD--HILYTGSTGVGKIIMT 198
Query: 271 TCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYE 330
A + VTLELGGKSP V + DLD A + IA+G F NSG+ C A I ++
Sbjct: 199 AAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQN 258
Query: 331 EVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGN 390
+++EK K+ + G +++ G S +++ G EG +V GG
Sbjct: 259 QIVEKLKKSLKEF-YGEDAKKSRDYGRIISARHFQRVM-----GLIEGQKVAYGGTGDAA 312
Query: 391 KGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDV 450
Y I PTI DV +++EEIFGPV+ + +++E + N E LA + + +
Sbjct: 313 TRY-IAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSND 371
Query: 451 NKAIDVSNRVKAGTVWIN---TYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKA 504
+ +G V N + H ++PFGG G SG+G G ++ + ++ ++
Sbjct: 372 KVIKKMIAETSSGGVAANDVIVHITLH-SLPFGGVGNSGMGSYHGKKSFETFSHRRS 427
>SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 548
Score = 139 bits (350), Expect = 1e-32
Identities = 129/502 (25%), Positives = 227/502 (44%), Gaps = 35/502 (6%)
Query: 14 IRLYSQLPLKVPVQLPNGITYEQPTGLFINGEFVPSRQHKTFEVLNPSNEEEITHIYEAR 73
++ Y +L ++PV +P I ++ I + P +HK +V+ + H+ +A
Sbjct: 31 VKAYKELEAELPVTIPVIIDGKEVETNTIGEQRCPF-EHK--KVVARYHRAGAKHVEDAI 87
Query: 74 EXXXXXXXXXXXXXFNNGWSTAEPEDRAKCLLKLADLID-QHAETLASIESLDNGKSLFC 132
E W + DR+ LK A LI ++ L + + GK+++
Sbjct: 88 EAALRGKKV---------WESLPFADRSAIFLKAAHLISTKYRYKLMAATMIGQGKNIWQ 138
Query: 133 SRGDVAL-VAKYLRSCAGWADKIYG-KVIDTGADHFSYTKREPL-GVCGQIIPWNFPLLM 189
+ D + + +LR +A ++Y + + ++ + PL G I P+NF +
Sbjct: 139 AEIDAGMEIIDFLRFNTKYASELYASQPPENTPGVWNRMEYRPLEGFVYAITPFNFTAIA 198
Query: 190 WSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICT 249
+ P L GN V++KP++ LS+ Q+ +EAG+P G + IPG V +
Sbjct: 199 GNLAAAPLLM-GNVVLMKPSDHAVLSSYIVYQIFREAGLPAGALQFIPGDAVEVSKVCFN 257
Query: 250 HPDIKKVAFTGSTATGRHIMKTCADSI--------KKVTLELGGKSPNIVFGDADLDKAV 301
HP+ + FTGSTA R + T +++ K+ E GGK+ ++V A++ AV
Sbjct: 258 HPEFAGLHFTGSTAVFRSLWGTIGENVANGKYRTYPKIVGETGGKNFHLVHSSAEIKSAV 317
Query: 302 KNIAFGIFYNSGEVCCAGSRIYVQDTVYEE-VLEKFKQYAESLKVGNPFEENV-FQGAQT 359
N F G+ C A SR+YV +E ++ + +SLKVG P + F G
Sbjct: 318 VNAVRAAFEYQGQKCSALSRLYVSKYAWENGFRDELTKQVKSLKVGAPLTDFANFVGPVI 377
Query: 360 SQMQIDKILSYVDVGTSEG-ARVITGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPV 418
Q +K+ ++ S+ V+ GG+ ++G+F++PT+ I E+FGPV
Sbjct: 378 HQASFNKLKKVLESAASDSEIEVLAGGKADDSEGFFVEPTVLLSKNPKHDIFVNELFGPV 437
Query: 419 VTVSKF--TTVDEVVAKAN-DSEYGLAAGIHTKDVNKAIDVSNRVK--AGTVWIN--TYN 471
++V + +D V + + YGL I +D +++R++ AG +IN
Sbjct: 438 LSVYVYEDDNLDAVCDLIDTTTPYGLTGSIFAQDRVVVRKLTDRLRNAAGNFYINDKCTG 497
Query: 472 NFHQNVPFGGFGQSGIGREMGA 493
PFGG SG + G+
Sbjct: 498 AVVGEQPFGGARASGTNDKAGS 519
>Hs4557303 [C] KOG2456 Aldehyde dehydrogenase
Length = 485
Score = 139 bits (349), Expect = 1e-32
Identities = 99/346 (28%), Positives = 173/346 (49%), Gaps = 26/346 (7%)
Query: 167 SYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEA 226
+Y + +PLGV I WN+P ++ + A+A GN V++KP+E + +A +L+ +
Sbjct: 95 AYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY 154
Query: 227 GVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIKKVTLELGGK 286
+ + + +I G + E + D + +TG+TA G+ +M+ A + VTLELGGK
Sbjct: 155 -LDQDLYIVINGGVEETTELLKQRFD--HIFYTGNTAVGKIVMEAAAKHLTPVTLELGGK 211
Query: 287 SPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQ-----YAE 341
SP + D DLD + I +G + N G+ C A I + ++ +++ K K+ Y E
Sbjct: 212 SPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEFYGE 271
Query: 342 SLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGYFIKPTIFA 401
++K +E + + +ILS + EG ++ GGE +I PT+
Sbjct: 272 NIKESPDYERII------NLRHFKRILSLL-----EGQKIAFGGE-TDEATRYIAPTVLT 319
Query: 402 DVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHT---KDVNKAIDVSN 458
DV ++++EEIFGP++ + VDE + N+ E LA + + K + + ID ++
Sbjct: 320 DVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETS 379
Query: 459 RVKAGTVWINTYNNFHQN-VPFGGFGQSGIGREMGAEALDNYTQTK 503
G + +F N PFGG G SG+G G + D ++ +
Sbjct: 380 --SGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQR 423
>Hs18603595 [C] KOG2456 Aldehyde dehydrogenase
Length = 508
Score = 139 bits (349), Expect = 1e-32
Identities = 99/346 (28%), Positives = 173/346 (49%), Gaps = 26/346 (7%)
Query: 167 SYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEA 226
+Y + +PLGV I WN+P ++ + A+A GN V++KP+E + +A +L+ +
Sbjct: 95 AYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY 154
Query: 227 GVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIKKVTLELGGK 286
+ + + +I G + E + D + +TG+TA G+ +M+ A + VTLELGGK
Sbjct: 155 -LDQDLYIVINGGVEETTELLKQRFD--HIFYTGNTAVGKIVMEAAAKHLTPVTLELGGK 211
Query: 287 SPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQ-----YAE 341
SP + D DLD + I +G + N G+ C A I + ++ +++ K K+ Y E
Sbjct: 212 SPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEFYGE 271
Query: 342 SLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGYFIKPTIFA 401
++K +E + + +ILS + EG ++ GGE +I PT+
Sbjct: 272 NIKESPDYERII------NLRHFKRILSLL-----EGQKIAFGGE-TDEATRYIAPTVLT 319
Query: 402 DVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHT---KDVNKAIDVSN 458
DV ++++EEIFGP++ + VDE + N+ E LA + + K + + ID ++
Sbjct: 320 DVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETS 379
Query: 459 RVKAGTVWINTYNNFHQN-VPFGGFGQSGIGREMGAEALDNYTQTK 503
G + +F N PFGG G SG+G G + D ++ +
Sbjct: 380 --SGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQR 423
>YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 575
Score = 137 bits (345), Expect = 4e-32
Identities = 122/462 (26%), Positives = 211/462 (45%), Gaps = 39/462 (8%)
Query: 40 LFINGEFV-PSRQHKTFEVLNPSNEEEI-THIYEAREXXXXXXXXXXXXXFNNGWSTAEP 97
L INGE + + + F NP+N +++ ++ +A E W
Sbjct: 63 LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA-KKDWYNLPF 121
Query: 98 EDRAKCLLKLADLID-QHAETLASIESLDNGKSLFCSRGD-VALVAKYLRSCAGWADKIY 155
DR+ LK ADLI ++ + + L GK+++ + D + ++ + R +A +Y
Sbjct: 122 YDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLY 181
Query: 156 GKVIDTGADHFSYTKRE--PL-GVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEAT 212
+ AD ++ K E PL G + P+NF + + PAL GNTVV KP++
Sbjct: 182 AQQPVESADG-TWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTA 239
Query: 213 PLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTC 272
LS +++EAG+PKGV+N IPG V +++ D + FTGST + +
Sbjct: 240 ALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKI 299
Query: 273 ADSI--------KKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYV 324
+ ++ E GGK+ ++V A++ AV + G F G+ C A SR+Y+
Sbjct: 300 QSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYL 359
Query: 325 QDTVYEEVLEKFKQYAESLKV------GNPFEE---NVFQGAQTSQMQIDKILSYV-DVG 374
++ EE L +S V +P F G + DK++ + D
Sbjct: 360 PESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAK 419
Query: 375 TSEGARVITGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTV-----SKFTTVDE 429
++ GG+ ++G+F+ PT+ + D + E FGP++TV ++F + +
Sbjct: 420 KDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICD 479
Query: 430 VVAKANDSEYGLAAGIHTKDVNKAIDVSN---RVKAGTVWIN 468
++ N S+Y L I KD KAI+ ++ + AG +IN
Sbjct: 480 II--DNTSQYALTGAIFAKD-RKAIEYADEKLKFSAGNFYIN 518
>Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 137 bits (345), Expect = 4e-32
Identities = 112/422 (26%), Positives = 199/422 (46%), Gaps = 25/422 (5%)
Query: 92 WSTAEPEDRAKCLLKLADLID--QHAETLASIESLDNGKSLFCSRGDVAL-VAKYLRSCA 148
W DRA+ LK AD++ + AE LA + GK++ + D A + + R A
Sbjct: 116 WDLKPIADRAQIFLKAADMLSGPRRAEILAKT-MVGQGKTVIQAEIDAAAELIDFFRFNA 174
Query: 149 GWADKIYGKV-IDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLK 207
+A ++ G+ I S R G I P+NF + + PAL GN V+ K
Sbjct: 175 KYAVELEGQQPISVPPSTNSTVYRGLEGFVAAISPFNFTAIGGNLAGAPALM-GNVVLWK 233
Query: 208 PAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRH 267
P++ L++ ++++EAG+P ++ +P G + G+ + + + + FTGS T +H
Sbjct: 234 PSDTAMLASYAVYRILREAGLPPNIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKH 293
Query: 268 IMKTCADSI------KKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSR 321
+ K A ++ ++ E GGK+ + V AD++ V F G+ C A SR
Sbjct: 294 LWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSR 353
Query: 322 IYVQDTVYEEVLEKFKQYAESLKVGNPFEE-NVFQGAQTSQMQIDKILSYVD-VGTSEGA 379
+YV +++ ++ + + +KVG+P E+ F A +I +++ +S
Sbjct: 354 LYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSL 413
Query: 380 RVITGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTV-----SKFTTVDEVVAKA 434
++ GG+ + GYF++P I I+KEEIFGPV++V K+ ++V
Sbjct: 414 TILAGGKCDDSVGYFVEPCIVESKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLV--D 471
Query: 435 NDSEYGLAAGIHTKDVNKAIDVSN--RVKAGTVWIN--TYNNFHQNVPFGGFGQSGIGRE 490
+ + YGL + ++D + + + R AG +IN + + PFGG SG +
Sbjct: 472 STTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYINDKSTGSIVGQQPFGGARASGTNDK 531
Query: 491 MG 492
G
Sbjct: 532 PG 533
>At1g44170 [C] KOG2456 Aldehyde dehydrogenase
Length = 484
Score = 136 bits (343), Expect = 7e-32
Identities = 121/421 (28%), Positives = 181/421 (42%), Gaps = 24/421 (5%)
Query: 98 EDRAKCLLKLADLIDQHAETLASIESLDNGKSLFCS--------RGDVALVAKYLRSCAG 149
E R L KL + D H + + D GK S R + L K L++
Sbjct: 32 EWRVTQLKKLMIICDNHEPEIVAALRDDLGKPELESSVYEVSLLRNSIKLALKQLKN--- 88
Query: 150 WADKIYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPA 209
W K T + EPLGV I WN+P L+ V A++ GN VVLKP+
Sbjct: 89 WMAPEKAKTSLTTFPASAEIVSEPLGVVLVISAWNYPFLLSIDPVIGAISAGNAVVLKPS 148
Query: 210 EATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIM 269
E P S+ +L+++ P V + G + K+ +TGS+ GR IM
Sbjct: 149 ELAPASSALLTKLLEQYLDPSAVRVVE---GAVTETSALLEQKWDKIFYTGSSKIGRVIM 205
Query: 270 KTCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIF-YNSGEVCCAGSRIYVQDTV 328
A + V LELGGKSP +V D DL V+ I G + N+G+ C + I
Sbjct: 206 AAAAKHLTPVVLELGGKSPVVVDSDTDLKVTVRRIIVGKWGCNNGQACVSPDYILTTKEY 265
Query: 329 YEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQM--QIDKILSYVDVGTSEGARVITGGE 386
++++ K E NP E S ++ K+L +V +++ GGE
Sbjct: 266 APKLIDAMKLELEKFYGKNPIESKDMSRIVNSNHFDRLSKLLDEKEVSD----KIVYGGE 321
Query: 387 RIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIH 446
+ + I PTI DV D I+ EEIFGP++ + ++E LAA +
Sbjct: 322 K-DRENLKIAPTILLDVPLDSLIMSEEIFGPLLPILTLNNLEESFDVIRSRPKPLAAYLF 380
Query: 447 TKDVNKAIDVSNRVKAGTVWIN--TYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKA 504
T + + V AG + +N + +PFGG G+SG+G G + D ++ KA
Sbjct: 381 THNKKLKERFAATVSAGGIVVNDIAVHLALHTLPFGGVGESGMGAYHGKFSFDAFSHKKA 440
Query: 505 V 505
V
Sbjct: 441 V 441
>7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 574
Score = 135 bits (340), Expect = 1e-31
Identities = 95/332 (28%), Positives = 160/332 (47%), Gaps = 15/332 (4%)
Query: 175 GVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVN 234
G + P+NF + + PAL GN V+ KP++ LS ++++EAGVP GVVN
Sbjct: 213 GFIAAVSPFNFTAIGGNLSYTPALM-GNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVN 271
Query: 235 IIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSI------KKVTLELGGKSP 288
+P G + G+ I P + + FTGS T + K ++I ++T E GGK+
Sbjct: 272 FVPADGPVFGDTITASPHLAGINFTGSVPTFNRLWKQVGNNIDNYVNFPRLTGECGGKNF 331
Query: 289 NIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQYAESLKVGNP 348
+ + AD++ V + F G+ C A SR+YV ++++ ++ E A LK+G+
Sbjct: 332 HFIHASADVESVVTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLVCEAAKLKIGDV 391
Query: 349 FEENVFQGAQTSQMQIDKILSYVD-VGTSEGARVITGGERIGNKGYFIKPTIFADVKEDM 407
+ + F A +I Y++ S ++ GG +KGYF+ PTI
Sbjct: 392 QDFSSFTSAVIDDKAFKRITGYIEHAKKSPNLEILAGGTYSDSKGYFVNPTIVLSKDPKD 451
Query: 408 QIVKEEIFGPVVTVSKFTTVD--EVVAKANDS-EYGLAAGIHTKDVN--KAIDVSNRVKA 462
+I+ EEIFGPV+++ + D E + + S ++ L + +D + K ++ A
Sbjct: 452 RIMTEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKMAA 511
Query: 463 GTVWIN--TYNNFHQNVPFGGFGQSGIGREMG 492
G +IN + + PFGG SG + G
Sbjct: 512 GNFYINDKSTGSVVGQQPFGGGRMSGTNDKAG 543
>Hs4502043 [C] KOG2456 Aldehyde dehydrogenase
Length = 468
Score = 132 bits (331), Expect = 2e-30
Identities = 114/421 (27%), Positives = 192/421 (45%), Gaps = 23/421 (5%)
Query: 94 TAEPEDRAKCLLKLADLIDQHAETLASIESLDNGKSLF--------CSRGDVALVAKYLR 145
T E RA L L + ++ + L + D KS F S+G+V L + LR
Sbjct: 20 TRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAISQGEVTLALRNLR 79
Query: 146 SCAGWADKIYGKVIDTGADHFSYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVV 205
A D+ K + T D ++ ++EP G+ I PWN+PL + + ALA GN VV
Sbjct: 80 --AWMKDERVPKNLATQLDS-AFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVV 136
Query: 206 LKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATG 265
LKP+E + +++ + V + ++ G + G+ + D + FTGS G
Sbjct: 137 LKPSEISKNVEKILAEVLPQY-VDQSCFAVVLGGPQETGQLLEHRFDY--IFFTGSPRVG 193
Query: 266 RHIMKTCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQ 325
+ +M A + VTLELGGK+P V + D +A+ ++N+G+ C A +
Sbjct: 194 KIVMTAAAKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCS 253
Query: 326 DTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGG 385
+ E +L + +P + + G +Q Q ++ + + G RV GG
Sbjct: 254 PEMQERLLPALQSTITRFYGDDP-QSSPNLGRIINQKQFQRLRALLGCG-----RVAIGG 307
Query: 386 ERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGI 445
+ + Y I PT+ DV+E +++EEIFGP++ + ++DE + N E LA
Sbjct: 308 QSDESDRY-IAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYA 366
Query: 446 HTKDVNKAIDVSNRVKAGTVWINT--YNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTK 503
+ V + +G N + ++PFGG G SG+GR G + D ++ +
Sbjct: 367 FSNSSQVVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGVGASGMGRYHGKFSFDTFSHHR 426
Query: 504 A 504
A
Sbjct: 427 A 427
>YMR110c [C] KOG2456 Aldehyde dehydrogenase
Length = 532
Score = 123 bits (309), Expect = 6e-28
Identities = 88/341 (25%), Positives = 162/341 (46%), Gaps = 26/341 (7%)
Query: 180 IIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGF 239
I P+NFPLL+ + ALA GNT+VLKP+E TP +A+ L+ AG P G++ ++ G
Sbjct: 135 IAPFNFPLLLAFAPLAAALAAGNTIVLKPSELTPHTAVVMENLLTTAGFPDGLIQVVQG- 193
Query: 240 GKIVGE--RICTHPDIKKVAFTGSTATGRHIMKTCADSIKKVTLELGGKSPNIV---FGD 294
+ E R+ + +TGS G + + A S+ LELGGKSP + F
Sbjct: 194 --AIDETTRLLDCGKFDLIFYTGSPRVGSIVAEKAAKSLTPCVLELGGKSPTFITENFKA 251
Query: 295 ADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEK----FKQYAESLKVGNPFE 350
+++ A+K I FG F NSG++C + + V ++Y +V+++ ++ S F
Sbjct: 252 SNIKIALKRIFFGAFGNSGQICVSPDYLLVHKSIYPKVIKECESVLNEFYPSFDEQTDFT 311
Query: 351 ENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKG---YFIKPTIFADVKEDM 407
+ + A + + ++ G++++ I + + PTI ++ D
Sbjct: 312 RMIHEPAYKK--------AVASINSTNGSKIVPSKISINSDTEDLCLVPPTIVYNIGWDD 363
Query: 408 QIVKEEIFGPVVTVSKFTTVDEVVAK-ANDSEYGLAAGIHTKDVNKAIDVSNRVKAG--T 464
++K+E F PV+ + ++ +DE + K + + L I + + + R+++G
Sbjct: 364 PLMKQENFAPVLPIIEYEDLDETINKIIEEHDTPLVQYIFSDSQTEINRILTRLRSGDCV 423
Query: 465 VWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAV 505
V + + PFGG G SG G G + ++ + +
Sbjct: 424 VGDTVIHVGITDAPFGGIGTSGYGNYGGYYGFNTFSHERTI 464
>Hs4502045 [C] KOG2456 Aldehyde dehydrogenase
Length = 385
Score = 123 bits (309), Expect = 6e-28
Identities = 90/341 (26%), Positives = 157/341 (45%), Gaps = 14/341 (4%)
Query: 171 REPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPK 230
+EP G+ I PWN+PL + + L GN VVLKP+E + + +++ + + +
Sbjct: 21 KEPFGLVLIIAPWNYPLNLTLVLLVGTLPAGNCVVLKPSEISQGTEKVLAEVLPQY-LDQ 79
Query: 231 GVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIKKVTLELGGKSPNI 290
++ G + G+ + + + FTGS G+ +M + VTLELGGK+P
Sbjct: 80 SCFAVVLGGPQETGQLL--EHKLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGKNPCY 137
Query: 291 VFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQYAESLKVGNPFE 350
V + D +A+ ++N+G+ C A + + E +L + +P +
Sbjct: 138 VDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDP-Q 196
Query: 351 ENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGYFIKPTIFADVKEDMQIV 410
+ G +Q Q ++ + + G RV GG+ +I PT+ DV+E ++
Sbjct: 197 SSPNLGRIINQKQFQRLRALLGCG-----RVAIGGQS-NESDRYIAPTVLVDVQETEPVM 250
Query: 411 KEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWIN-- 468
+EEIFGP++ + +VDE + N E LA + + R +G+ N
Sbjct: 251 QEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSRQVVNQMLERTSSGSFGGNEG 310
Query: 469 -TYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAVRMA 508
TY + +VPFGG G SG+GR G D ++ + +A
Sbjct: 311 FTYISL-LSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLA 350
>7304212 [C] KOG2456 Aldehyde dehydrogenase
Length = 561
Score = 106 bits (265), Expect = 7e-23
Identities = 108/402 (26%), Positives = 162/402 (39%), Gaps = 83/402 (20%)
Query: 172 EPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKG 231
+P GV I WN+PL + V A+A GN VV+KP+E A + ++ PK
Sbjct: 103 DPFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVI-----PKY 157
Query: 232 VVN----IIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIKKVTLELGGKS 287
+ N ++ G E + D + +TGST G+ I + TLELGGKS
Sbjct: 158 LDNDCYPVVCGGPSETAELLNQRFDY--IFYTGSTRVGKIIHAAANKYLTPTTLELGGKS 215
Query: 288 PNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQYAESLKVGN 347
P + D+ AVK I +G N G+ C A I +EV EKF A+ + +
Sbjct: 216 PCYIDKSVDMRTAVKRILWGKLINCGQTCIAPDYILCS----KEVQEKFIVEAKDV-LKE 270
Query: 348 PFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGYFIKPTIFADVKEDM 407
+ EN+ S++ I+ +G + RV GG ++ FI+PTI DVKE
Sbjct: 271 WYGENIQSSPDLSRV-INANNFQRLLGLMKSGRVAVGGNYDASE-RFIEPTILVDVKETD 328
Query: 408 QIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLA------------------------- 442
I++EEIFGP++ + + + + N E L
Sbjct: 329 PIMEEEIFGPILPIFNVESAYDAIKFINARESPLVLYIFTPTAEVQNLFINGTQSGGLCV 388
Query: 443 -------AGIHTKDVN---------KAIDVSNRVKAGTVWI--------------NTYNN 472
AG + VN A+D N+ K +++ T
Sbjct: 389 NDTIMHYAGKNPTSVNPKVAPIEMLMAVDYDNKEKPLVIYVFSNSNKLVKEFRRSTTSGG 448
Query: 473 FHQN----------VPFGGFGQSGIGREMGAEALDNYTQTKA 504
F N +PFGG G SG+GR G + +T K+
Sbjct: 449 FSSNETIMHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKS 490
>7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 1590
Score = 102 bits (255), Expect = 1e-21
Identities = 89/351 (25%), Positives = 163/351 (46%), Gaps = 23/351 (6%)
Query: 175 GVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVN 234
G I P+NF + + PAL GN+V+ KP+++ LS + + ++EAGVP GVVN
Sbjct: 235 GFVAAISPFNFTGIAANLAYTPALM-GNSVIWKPSDSAILSNYFVFKALREAGVPDGVVN 293
Query: 235 IIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIK------KVTLELGGKSP 288
+P + HP + + FTG++ + + + A +I ++ E GGK+
Sbjct: 294 FVPAEETTFASVVTQHPKLAGINFTGTSTVLKVLWQLVAQNINFYQNYPRLVGEGGGKNF 353
Query: 289 NIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYE-EVLEKFKQYAESLKVGN 347
+ V A+ + AV F +G+ C + S +YV +++++ + E + SL V
Sbjct: 354 HFVHSSAEPETAVACTIRAAFEYAGQKCSSCSMLYVPESLWQNHIREPLLEITASLVVRQ 413
Query: 348 PFEE-NVFQGAQTSQMQIDKI---LSYVDVGTSEGARVITGGERIGNKGYFIKPTIFADV 403
+ F A ++ D+I L Y+D S +++ GG +GY++ PT+
Sbjct: 414 DATYCDSFCSAVINRRAYDRIYMWLRYID--QSPSCQILVGGSCDKRRGYYVDPTVVLVK 471
Query: 404 KEDMQIVKEEIFGPVVTVSKFT--TVDEVVAKANDSEYGLAAGIHTKDVN---KAIDVSN 458
D I +EE+ P++ V + + E + K +GL + +D N +A D +
Sbjct: 472 DLDNIICREELLAPILGVYVYPDHKLKETMEKVAQINHGLTGSVFAQDQNFIEEAYD-AF 530
Query: 459 RVKAGTVWINTYNN--FHQNVPFGGFGQSGIGREMGA-EALDNYTQTKAVR 506
RV G + +N + PFG +G ++G +L +T + ++
Sbjct: 531 RVNVGNLNVNDKSTGLMVGQQPFGAGHMTGTSDKLGTPHSLLRWTSPQVIK 581
>At4g36250 [C] KOG2456 Aldehyde dehydrogenase
Length = 433
Score = 97.4 bits (241), Expect = 4e-20
Identities = 86/338 (25%), Positives = 136/338 (39%), Gaps = 59/338 (17%)
Query: 172 EPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEAGVPKG 231
EP G + WNFP+ + + A+A GNTV+LK +E +P ++ + + + A +
Sbjct: 107 EPYGTVLVLSSWNFPISLSLDPLIGAIAAGNTVLLKSSELSPNASAFLAKTIP-AYLDTK 165
Query: 232 VVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIKKVTLELGGKSPNIV 291
+ +I G G V + H K+ FTGS GR IM A + VTLELGGKS
Sbjct: 166 AIKVIEG-GPDVATILLQH-QWDKIFFTGSPKIGRIIMAAAAQHLTPVTLELGGKS---- 219
Query: 292 FGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQYAESLKVGNPFEE 351
C + + ++ + +++ K +S NP E
Sbjct: 220 ------------------------CISVDYVLIEKSFAPTLIDMLKPTIKSFFGENPKES 255
Query: 352 NVFQGAQTSQ--MQIDKILSYVDVGTSEGARVITGGERIGNKGYFIKPTIFADVKEDMQI 409
++ ++LS +PTI D D +I
Sbjct: 256 GCLSRIANKHHVQRLSRLLSDP------------------------RPTILLDPPLDSEI 291
Query: 410 VKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWIN- 468
+ EEIFGP++ + + E + N LA T D N + + +G+V N
Sbjct: 292 MNEEIFGPILPIITVRDIQESIGIINTKPKPLAIYAFTNDENLKTRILSETSSGSVTFND 351
Query: 469 -TYNNFHQNVPFGGFGQSGIGREMGAEALDNYTQTKAV 505
+PFGG G+SGIGR G + D ++ KA+
Sbjct: 352 VMIQYMCDALPFGGVGESGIGRYHGKYSFDCFSHEKAI 389
>7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 560
Score = 83.2 bits (204), Expect = 9e-16
Identities = 101/468 (21%), Positives = 183/468 (38%), Gaps = 23/468 (4%)
Query: 63 EEEITHIYEAREXXXXXXXXXXXXXFNNGWSTAEPEDRAKCLLKLADLIDQHAETLASIE 122
+ + H+Y A WS R + A +I++ L
Sbjct: 88 QTNLAHVYYANRKQIEAAIKSALSA-QGTWSLVPIAQRLAIWRRAATIIEEDELRLRVFL 146
Query: 123 SLDNGKSLFCSRGDVALVAKYLRSCAGWADKIYGKVIDTGADHF---SYTKREPLGVCGQ 179
+ K+ + D+ + LR+ A + + + + D S+ R G
Sbjct: 147 MMTLSKTADDATRDIRRLLTSLRANADYLEHLSELRFEIQGDMNVFPSFHLRPMDGFVAA 206
Query: 180 IIPWNFPLLMWSWKVGPALATGNTVVLKPA-EATPLSALYACQLVQEAGVPKGVVNIIPG 238
+ P+ L S + PAL GNTV+ P+ E P+S L + QEAG+P GV+N +P
Sbjct: 207 LAPFESVALSSSLALCPALM-GNTVLWNPSLEVAPVSYLIF-RAFQEAGLPSGVINFVPA 264
Query: 239 FGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIK------KVTLELGGKSPNIVF 292
++ + I + S A RH+ K +D ++ ++ E G++ + V
Sbjct: 265 NERLFLDTITDAVHFAGLNTQASAAFYRHVHKLVSDRMERYICFPRLVAECPGQNFHFVH 324
Query: 293 GDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVLEKFKQYAESLKVGNPFEEN 352
A ++ V F +G+ + SR+YV +++ + E+ + E L +G+P E
Sbjct: 325 ASAKVESVVSATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVEATEQLTIGDPIESE 384
Query: 353 VFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKGYFIKPTIFADVKEDMQIVKE 412
GA ++ + ++ + GG + G F+ PTI ++ E
Sbjct: 385 TDIGAMVHINDFRRMQKLLQ--RTKNMEQLCGGSCDDSTGRFVDPTIVRVSDPLDPLLCE 442
Query: 413 EIFGPVVTV---SKFTTVDEVVAKANDSEYGLAAGIHTKDVNKAIDVSN--RVKAGTVWI 467
GP + V S + + + AN S Y L+ I + N R+ A +++
Sbjct: 443 PCCGPFLPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSASNLYV 502
Query: 468 N--TYNNFHQNVPFGGFGQSGIGREMG-AEALDNYTQTKAVRMAIDHP 512
N + + PFGG SG + G A L ++ + +D P
Sbjct: 503 NERCTGSTYGLTPFGGNRLSGTNDKSGSAYFLMRWSSPLLIEETVDGP 550
>Hs20481620 [C] KOG2456 Aldehyde dehydrogenase
Length = 292
Score = 78.2 bits (191), Expect = 3e-14
Identities = 49/167 (29%), Positives = 84/167 (49%), Gaps = 3/167 (1%)
Query: 167 SYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLKPAEATPLSALYACQLVQEA 226
++ ++EP G+ I PWN+PL + + ALA GN VVLKP+E + +++ +
Sbjct: 61 AFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKILAEVLPQY 120
Query: 227 GVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRHIMKTCADSIKKVTLELGGK 286
V + ++ G + G+ + D + FTGS G+ +M A + VTLELGGK
Sbjct: 121 -VDQSCFAVVLGGPQETGQLLEHRFDY--IFFTGSPRVGKIVMTAAAKHLTPVTLELGGK 177
Query: 287 SPNIVFGDADLDKAVKNIAFGIFYNSGEVCCAGSRIYVQDTVYEEVL 333
+P V + D +A+ ++N+G+ C A + + E +L
Sbjct: 178 NPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLL 224
>At4g34240 [C] KOG2456 Aldehyde dehydrogenase
Length = 533
Score = 68.2 bits (165), Expect = 3e-11
Identities = 73/313 (23%), Positives = 122/313 (38%), Gaps = 25/313 (7%)
Query: 197 ALATGNTVVLKPAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKV 256
A+A GN VVLKP+E P ++ +L E + + +I G + K+
Sbjct: 196 AIAAGNAVVLKPSEIAPAASSLLAKLFSEY-LDNTTIRVIEG--GVPETTALLDQKWDKI 252
Query: 257 AFTGSTATGRHIMKTCADSIKKVTLELGGKSPNIVFGDADLDKAVKNIAFGIFYNSGEVC 316
FT + +H + V L L + I+ G NSG+ C
Sbjct: 253 FFTDLSLLLKHKIVKFRSHTLIVVLWLKVAARRIIAGKWAC-------------NSGQAC 299
Query: 317 CAGSRIYVQDTVYEEVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTS 376
+ ++++ K E+ F +N + S++ ++
Sbjct: 300 IGVDYVITTKDFASKLIDALKTELETF-----FGQNALESKDLSRIVNSFHFKRLESMLK 354
Query: 377 EG--ARVITGGERIGNKGYFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKA 434
E A I G RI I PTI DV E +++EEIFGP++ + +++
Sbjct: 355 ENGVANKIVHGGRITEDKLKISPTILLDVPEASSMMQEEIFGPLLPIITVQKIEDGFQVI 414
Query: 435 NDSEYGLAAGIHTKDVNKAIDVSNRVKAGTVWIN--TYNNFHQNVPFGGFGQSGIGREMG 492
LAA + T + V AG + IN + +++PFGG G+SGIG G
Sbjct: 415 RSKPKPLAAYLFTNNKELEKQFVQDVSAGGITINDTVLHVTVKDLPFGGVGESGIGAYHG 474
Query: 493 AEALDNYTQTKAV 505
+ + ++ K V
Sbjct: 475 KFSYETFSHKKGV 487
>Hs20479244 [C] KOG2450 Aldehyde dehydrogenase
Length = 292
Score = 65.9 bits (159), Expect = 1e-10
Identities = 43/167 (25%), Positives = 82/167 (48%), Gaps = 2/167 (1%)
Query: 333 LEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGGERIGNKG 392
+ + ++ L+ G + V GA+ + D + +V S+GA+V G+ + ++
Sbjct: 1 MRRLQERMGRLRSGRGLDGAVDMGARGAAA-CDLVQRFVREAQSQGAQVFQAGD-VPSER 58
Query: 393 YFIKPTIFADVKEDMQIVKEEIFGPVVTVSKFTTVDEVVAKANDSEYGLAAGIHTKDVNK 452
F PT+ +++ + E+ PVV S F T E + AN + G +A + ++ + +
Sbjct: 59 PFYPPTLVSNLPPASPCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLGQ 118
Query: 453 AIDVSNRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGAEALDNY 499
A+++ ++ GTVWIN + +VP GG +SG G + L Y
Sbjct: 119 ALELGYGLQVGTVWINAHGLRDPSVPTGGCKESGCSWHGGPDGLYEY 165
>At5g62530 [C] KOG2451 Aldehyde dehydrogenase
Length = 563
Score = 58.9 bits (141), Expect = 2e-08
Identities = 88/411 (21%), Positives = 170/411 (40%), Gaps = 43/411 (10%)
Query: 42 INGEFVPSRQHKTFEVLNPSNEEEITHIYEAREXXXXXXXXXXXXXFNNGWSTA--EPE- 98
+ G+++ S H T +L+P N E + E E +G PE
Sbjct: 64 VQGKWIGSSNHNT--LLDPLNGEPFIKVAEVDESGTQPFVDSLSQCPKHGLHNPFKSPER 121
Query: 99 --------DRAKCLLKLADLIDQHAETLASIESLDNGKSLFCSRGDVALVAKYLRSCAGW 150
+A +L L + D A + + KS + G+V + K+L + G
Sbjct: 122 YLLYGDISTKAAHMLALPKVADFFARLIQRVAP----KSYQQAAGEVFVTRKFLENFCGD 177
Query: 151 ADKIYGKVIDTGADHF---SYTKREPLGVCGQIIPWNFPLLMWSWKVGPALATGNTVVLK 207
+ + +H S+ R P G + P+NFPL + ++ AL GN +LK
Sbjct: 178 QVRFLARSFAIPGNHLGQQSHGYRWPYGPVTIVTPFNFPLEIPLLQLMGALYMGNKPLLK 237
Query: 208 PAEATPLSALYACQLVQEAGVPKGVVNIIPGFGKIVGERICTHPDIKKVAFTGSTATGRH 267
+ +L+ G+P V+ I GK + +I + + FTGS+ R
Sbjct: 238 VDSKVSIVMEQMMRLLHYCGLPAEDVDFINSDGKTM-NKILLEANPRMTLFTGSS---RV 293
Query: 268 IMKTCADSIKKVTLELGGKSPNIVFGDA-DLDKAVKNIAFGIFYNSGEVCCAGSRIYVQD 326
K D ++ LE G ++ D ++D + SG+ C A S ++V +
Sbjct: 294 AEKLALDLKGRIRLEDAGFDWKVLGPDVQEVDYVAWQCDQDAYACSGQKCSAQSMLFVHE 353
Query: 327 TVYE-EVLEKFKQYAESLKVGNPFEENVFQGAQTSQMQIDKILSYVDVGTSEGARVITGG 385
+ ++ K K+ AE K+ + V T++ ++ + + + + G++++ GG
Sbjct: 354 NWSKTPLVSKLKELAERRKLEDLTIGPVL--TFTTEAMLEHMENLLQI---PGSKLLFGG 408
Query: 386 ERIGNKGY-----FIKPT-IFADVKEDM------QIVKEEIFGPVVTVSKF 424
+ + N ++PT ++ ++E + ++V +EIFGP V+++
Sbjct: 409 KELKNHSIPSIYGALEPTAVYVPIEEILKDNKTYELVTKEIFGPFQIVTEY 459
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,677,109
Number of Sequences: 60738
Number of extensions: 1354672
Number of successful extensions: 3183
Number of sequences better than 1.0e-05: 76
Number of HSP's better than 0.0 without gapping: 71
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2861
Number of HSP's gapped (non-prelim): 84
length of query: 514
length of database: 30,389,216
effective HSP length: 111
effective length of query: 403
effective length of database: 23,647,298
effective search space: 9529861094
effective search space used: 9529861094
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)