ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2109 check: MH T KOG4645 Signal transduction mechanisms MAPKKK (MAP kinase kinase kinase) SSK2 and related serine/threonine protein kinases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII2109 744554 749206 1551
(1551 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 1269 0.0
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 1088 0.0
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 406 e-112
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 212 4e-54
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 212 4e-54
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 209 4e-53
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 208 5e-53
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 202 3e-51
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 201 8e-51
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 184 1e-45
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 184 1e-45
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 180 1e-44
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 179 4e-44
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 174 1e-42
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 173 2e-42
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 171 8e-42
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 168 7e-41
At4g08480 [T] KOG0198 MEKK and related serine/threonine protein ... 163 2e-39
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 160 1e-38
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 157 2e-37
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 155 6e-37
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 155 6e-37
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 154 8e-37
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 154 1e-36
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 154 1e-36
CE27177 [T] KOG4279 Serine/threonine protein kinase 154 1e-36
At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protei... 153 2e-36
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 153 2e-36
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 153 2e-36
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 152 5e-36
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 150 1e-35
At4g08470 [T] KOG0198 MEKK and related serine/threonine protein ... 149 3e-35
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 149 3e-35
At1g07150 [T] KOG0198 MEKK and related serine/threonine protein ... 148 6e-35
At4g26890 [T] KOG0198 MEKK and related serine/threonine protein ... 148 8e-35
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 146 2e-34
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 146 2e-34
CE27573 [T] KOG0198 MEKK and related serine/threonine protein ki... 145 4e-34
CE07737 [T] KOG0198 MEKK and related serine/threonine protein ki... 145 4e-34
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 144 1e-33
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 144 1e-33
7300559 [T] KOG4279 Serine/threonine protein kinase 144 1e-33
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 143 2e-33
At2g32510 [T] KOG0198 MEKK and related serine/threonine protein ... 143 2e-33
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 143 2e-33
7293601 [T] KOG0577 Serine/threonine protein kinase 143 2e-33
SPAC1006.09 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 a... 142 3e-33
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 142 5e-33
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 141 7e-33
At3g15220 [T] KOG0201 Serine/threonine protein kinase 141 7e-33
At1g53165 [T] KOG0201 Serine/threonine protein kinase 141 7e-33
At1g05100 [T] KOG0198 MEKK and related serine/threonine protein ... 139 3e-32
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 139 4e-32
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 138 6e-32
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 138 8e-32
At5g55090 [T] KOG0198 MEKK and related serine/threonine protein ... 137 1e-31
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 137 2e-31
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 136 3e-31
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 136 3e-31
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 135 5e-31
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 135 5e-31
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 135 5e-31
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 134 9e-31
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 134 9e-31
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 134 1e-30
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 134 1e-30
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 134 1e-30
At2g25090 [T] KOG0583 Serine/threonine protein kinase 133 2e-30
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 133 3e-30
YHR102w [T] KOG0201 Serine/threonine protein kinase 132 6e-30
7300224 [T] KOG0201 Serine/threonine protein kinase 132 6e-30
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 131 7e-30
At5g67080 [T] KOG0198 MEKK and related serine/threonine protein ... 131 1e-29
At4g30960 [T] KOG0583 Serine/threonine protein kinase 131 1e-29
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 131 1e-29
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 130 1e-29
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 130 2e-29
At5g35410 [T] KOG0583 Serine/threonine protein kinase 130 2e-29
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 129 3e-29
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 129 3e-29
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 129 4e-29
At5g25110 [T] KOG0583 Serine/threonine protein kinase 129 5e-29
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 128 6e-29
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 128 8e-29
At2g30360 [T] KOG0583 Serine/threonine protein kinase 128 8e-29
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 127 1e-28
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 127 1e-28
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 127 1e-28
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 127 1e-28
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 127 1e-28
At5g01810 [T] KOG0583 Serine/threonine protein kinase 127 1e-28
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 126 2e-28
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 126 2e-28
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 126 2e-28
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 126 2e-28
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 126 3e-28
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 126 3e-28
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 126 3e-28
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 126 3e-28
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 126 3e-28
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 125 4e-28
At5g10930 [T] KOG0583 Serine/threonine protein kinase 125 4e-28
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 125 5e-28
At3g50310 [T] KOG0198 MEKK and related serine/threonine protein ... 124 9e-28
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 9e-28
SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-speci... 124 1e-27
At2g30040 [T] KOG0198 MEKK and related serine/threonine protein ... 124 2e-27
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 123 3e-27
CE28674 [T] KOG0201 Serine/threonine protein kinase 123 3e-27
CE07510 [T] KOG0201 Serine/threonine protein kinase 123 3e-27
At4g18700 [T] KOG0583 Serine/threonine protein kinase 123 3e-27
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 123 3e-27
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 122 3e-27
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 122 3e-27
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 122 4e-27
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 122 6e-27
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 122 6e-27
At2g45490 [D] KOG0580 Serine/threonine protein kinase 122 6e-27
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 121 1e-26
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 121 1e-26
At1g73500 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 120 1e-26
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 120 2e-26
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 120 2e-26
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 120 2e-26
At1g30270 [T] KOG0583 Serine/threonine protein kinase 120 2e-26
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 119 3e-26
At3g45670 [T] KOG0198 MEKK and related serine/threonine protein ... 119 3e-26
YCL024w [T] KOG0583 Serine/threonine protein kinase 119 4e-26
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 119 4e-26
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 119 4e-26
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 119 4e-26
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 119 5e-26
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 119 5e-26
Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 119 5e-26
At3g46140 [T] KOG0198 MEKK and related serine/threonine protein ... 119 5e-26
YDR507c [D] KOG0588 Serine/threonine protein kinase 118 6e-26
At5g45820 [T] KOG0583 Serine/threonine protein kinase 118 6e-26
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 118 6e-26
YKL101w [D] KOG0588 Serine/threonine protein kinase 118 8e-26
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 118 8e-26
Hs13376582 [T] KOG0198 MEKK and related serine/threonine protein... 118 8e-26
At4g24400 [T] KOG0583 Serine/threonine protein kinase 118 8e-26
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 117 1e-25
At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 117 1e-25
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 117 1e-25
At1g29230 [T] KOG0583 Serine/threonine protein kinase 117 1e-25
At5g45810 [T] KOG0583 Serine/threonine protein kinase 117 1e-25
At1g18350 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 117 1e-25
At1g01140 [T] KOG0583 Serine/threonine protein kinase 117 1e-25
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 117 2e-25
At2g26980 [T] KOG0583 Serine/threonine protein kinase 117 2e-25
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 116 2e-25
CE01405 [T] KOG0577 Serine/threonine protein kinase 116 2e-25
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 116 2e-25
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 116 3e-25
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 116 3e-25
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 115 4e-25
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 115 4e-25
At4g32830 [D] KOG0580 Serine/threonine protein kinase 115 4e-25
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 115 4e-25
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 115 4e-25
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 115 5e-25
At2g38490 [T] KOG0583 Serine/threonine protein kinase 115 5e-25
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 115 5e-25
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 115 5e-25
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 115 7e-25
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 115 7e-25
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 115 7e-25
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 115 7e-25
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 114 9e-25
CE07399 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kina... 114 9e-25
At5g01820 [T] KOG0583 Serine/threonine protein kinase 114 9e-25
At3g45790 [T] KOG0198 MEKK and related serine/threonine protein ... 114 9e-25
SPBC409.07c [T] KOG0581 Mitogen-activated protein kinase kinase ... 114 1e-24
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 114 1e-24
Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 114 1e-24
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 114 2e-24
At5g07070 [T] KOG0583 Serine/threonine protein kinase 114 2e-24
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 114 2e-24
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 113 2e-24
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 113 2e-24
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 113 2e-24
At2g25880 [D] KOG0580 Serine/threonine protein kinase 113 2e-24
YDR523c [T] KOG0201 Serine/threonine protein kinase 113 3e-24
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 113 3e-24
CE17284 [T] KOG0583 Serine/threonine protein kinase 113 3e-24
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 113 3e-24
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 113 3e-24
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 112 4e-24
YJL128c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 112 4e-24
At5g58380 [T] KOG0583 Serine/threonine protein kinase 112 4e-24
At5g40440 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 112 4e-24
7290147 [T] KOG0583 Serine/threonine protein kinase 112 4e-24
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 112 5e-24
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 112 5e-24
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 112 5e-24
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 112 5e-24
CE23001 [R] KOG0589 Serine/threonine protein kinase 112 5e-24
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 112 5e-24
At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase 112 5e-24
At3g29160 [T] KOG0583 Serine/threonine protein kinase 112 5e-24
At2g34180 [T] KOG0583 Serine/threonine protein kinase 112 5e-24
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 112 6e-24
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 112 6e-24
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 112 6e-24
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 112 6e-24
At5g39440 [T] KOG0583 Serine/threonine protein kinase 112 6e-24
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 112 6e-24
At3g01090 [T] KOG0583 Serine/threonine protein kinase 112 6e-24
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 111 8e-24
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 111 8e-24
At3g17510 [T] KOG0583 Serine/threonine protein kinase 111 8e-24
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 111 1e-23
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 111 1e-23
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 111 1e-23
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 111 1e-23
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 111 1e-23
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 111 1e-23
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 111 1e-23
At3g20860 [R] KOG0589 Serine/threonine protein kinase 111 1e-23
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 111 1e-23
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 110 1e-23
At3g18750 [R] KOG0584 Serine/threonine protein kinase 110 1e-23
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 110 1e-23
At5g27790 [T] KOG0198 MEKK and related serine/threonine protein ... 110 2e-23
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 110 2e-23
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 110 2e-23
YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 110 2e-23
Hs4506889 [T] KOG1006 Mitogen-activated protein kinase (MAPK) ki... 110 2e-23
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 110 2e-23
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 110 2e-23
7300106 [T] KOG0690 Serine/threonine protein kinase 110 2e-23
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 109 3e-23
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 109 3e-23
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 109 3e-23
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 109 3e-23
At2g41930 [T] KOG0198 MEKK and related serine/threonine protein ... 109 3e-23
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 109 3e-23
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 109 3e-23
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 109 4e-23
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 109 4e-23
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 109 4e-23
At2g34290 [T] KOG0198 MEKK and related serine/threonine protein ... 109 4e-23
At2g05060 [T] KOG0198 MEKK and related serine/threonine protein ... 109 4e-23
At1g32320 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 109 4e-23
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 109 4e-23
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 108 5e-23
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 108 5e-23
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 108 5e-23
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 108 5e-23
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 108 5e-23
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 108 5e-23
CE25437 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 108 5e-23
At4g14580 [T] KOG0583 Serine/threonine protein kinase 108 5e-23
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 5e-23
7303211 [T] KOG4717 Serine/threonine protein kinase 108 5e-23
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 108 5e-23
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 108 7e-23
At5g58350 [R] KOG0584 Serine/threonine protein kinase 108 7e-23
At5g57630 [T] KOG0583 Serine/threonine protein kinase 108 7e-23
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 108 9e-23
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 108 9e-23
CE21025 [D] KOG0580 Serine/threonine protein kinase 108 9e-23
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 9e-23
7299536 [D] KOG0580 Serine/threonine protein kinase 108 9e-23
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 108 9e-23
YPL209c [D] KOG0580 Serine/threonine protein kinase 107 1e-22
Hs21729895 [T] KOG0581 Mitogen-activated protein kinase kinase (... 107 1e-22
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 107 1e-22
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 107 1e-22
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 107 1e-22
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 107 1e-22
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 107 1e-22
Hs18602554 [T] KOG0578 p21-activated serine/threonine protein ki... 107 1e-22
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 107 1e-22
At2g41920 [T] KOG0198 MEKK and related serine/threonine protein ... 107 1e-22
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 1e-22
7301213 [R] KOG0589 Serine/threonine protein kinase 107 1e-22
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 107 1e-22
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 107 2e-22
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 107 2e-22
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 107 2e-22
CE24761 [D] KOG0580 Serine/threonine protein kinase 106 3e-22
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 106 3e-22
At4g24100 [T] KOG0582 Ste20-like serine/threonine protein kinase 106 3e-22
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 3e-22
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 3e-22
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 106 3e-22
7291037 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 106 3e-22
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 106 3e-22
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 106 3e-22
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 105 4e-22
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 105 4e-22
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 105 4e-22
At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 105 4e-22
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 4e-22
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 4e-22
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 105 4e-22
At1g49160 [R] KOG0584 Serine/threonine protein kinase 105 4e-22
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 105 6e-22
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 105 6e-22
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 105 6e-22
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 105 6e-22
At5g39420 [D] KOG0600 Cdc2-related protein kinase 105 6e-22
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 6e-22
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 105 7e-22
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 105 7e-22
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 105 7e-22
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 105 7e-22
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 105 7e-22
CE03979 [T] KOG0614 cGMP-dependent protein kinase 105 7e-22
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 7e-22
YDL159w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 104 1e-21
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 104 1e-21
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 104 1e-21
At3g23000 [T] KOG0583 Serine/threonine protein kinase 104 1e-21
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 104 1e-21
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 104 1e-21
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 104 1e-21
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 103 2e-21
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 103 2e-21
At5g41990 [R] KOG0584 Serine/threonine protein kinase 103 2e-21
At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase 103 2e-21
At3g06230 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 103 2e-21
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 2e-21
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 103 2e-21
SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases 103 2e-21
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 103 2e-21
Hs4757868 [T] KOG0193 Serine/threonine protein kinase RAF 103 2e-21
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 103 2e-21
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 103 2e-21
CE28479 [T] KOG0583 Serine/threonine protein kinase 103 2e-21
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 103 2e-21
At3g51630 [R] KOG0584 Serine/threonine protein kinase 103 2e-21
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 2e-21
At1g48260 [T] KOG0583 Serine/threonine protein kinase 103 2e-21
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 103 2e-21
Hs4506401 [T] KOG0193 Serine/threonine protein kinase RAF 103 3e-21
CE28643 [T] KOG0583 Serine/threonine protein kinase 103 3e-21
CE07458 [T] KOG0583 Serine/threonine protein kinase 103 3e-21
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 3e-21
At1g53050 [D] KOG0600 Cdc2-related protein kinase 103 3e-21
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 102 4e-21
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 4e-21
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 102 4e-21
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 102 4e-21
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 4e-21
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 102 5e-21
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 102 5e-21
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 5e-21
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 5e-21
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 102 5e-21
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 102 6e-21
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 102 6e-21
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 102 6e-21
CE29622 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kina... 102 6e-21
CE08727 [G] KOG0658 Glycogen synthase kinase-3 102 6e-21
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 102 6e-21
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 102 6e-21
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 102 6e-21
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 6e-21
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 6e-21
7297080 [T] KOG0583 Serine/threonine protein kinase 102 6e-21
7296451 [D] KOG0600 Cdc2-related protein kinase 102 6e-21
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 101 8e-21
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 101 8e-21
YBL016w [T] KOG0660 Mitogen-activated protein kinase 101 8e-21
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 101 8e-21
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 101 8e-21
CE26422 [D] KOG0600 Cdc2-related protein kinase 101 8e-21
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 8e-21
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 8e-21
At1g67890 [T] KOG0192 Tyrosine kinase specific for activated (GT... 101 8e-21
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 101 8e-21
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 101 1e-20
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 101 1e-20
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 101 1e-20
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 101 1e-20
CE28218 [D] KOG0588 Serine/threonine protein kinase 101 1e-20
At5g50860 [D] KOG0600 Cdc2-related protein kinase 101 1e-20
At3g06620 [T] KOG0192 Tyrosine kinase specific for activated (GT... 101 1e-20
At1g74330 [D] KOG0600 Cdc2-related protein kinase 101 1e-20
7290150 [T] KOG0583 Serine/threonine protein kinase 101 1e-20
HsM4885147 [T] KOG0201 Serine/threonine protein kinase 100 1e-20
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 100 1e-20
Hs22035598 [T] KOG0201 Serine/threonine protein kinase 100 1e-20
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 100 1e-20
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 100 1e-20
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 100 1e-20
CE03080 [R] KOG0584 Serine/threonine protein kinase 100 1e-20
At5g12090 [T] KOG0198 MEKK and related serine/threonine protein ... 100 1e-20
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 100 1e-20
At3g05050 [D] KOG0600 Cdc2-related protein kinase 100 1e-20
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 1e-20
At2g41910 [T] KOG0198 MEKK and related serine/threonine protein ... 100 1e-20
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 100 2e-20
Hs22065797 [T] KOG0577 Serine/threonine protein kinase 100 2e-20
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 100 2e-20
CE25585 [T] KOG0193 Serine/threonine protein kinase RAF 100 2e-20
CE24941 [T] KOG0983 Mitogen-activated protein kinase (MAPK) kina... 100 2e-20
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 100 2e-20
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 100 2e-20
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 2e-20
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 2e-20
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 2e-20
At1g54610 [D] KOG0600 Cdc2-related protein kinase 100 2e-20
At1g14000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 100 2e-20
SPAC29A4.16 [D] KOG0590 Checkpoint kinase and related serine/thr... 100 2e-20
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 2e-20
Hs21735542 [T] KOG0983 Mitogen-activated protein kinase (MAPK) k... 100 2e-20
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 100 2e-20
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 100 2e-20
CE27410 [T] KOG0583 Serine/threonine protein kinase 100 2e-20
CE10328 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kina... 100 2e-20
At3g06640 [T] KOG0192 Tyrosine kinase specific for activated (GT... 100 2e-20
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 100 3e-20
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 100 3e-20
Hs4506101 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 100 3e-20
Hs21729897 [T] KOG0581 Mitogen-activated protein kinase kinase (... 100 3e-20
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 100 3e-20
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 100 3e-20
CE29020 [T] KOG0660 Mitogen-activated protein kinase 100 3e-20
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 100 3e-20
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 3e-20
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 100 3e-20
YPR161c [D] KOG0600 Cdc2-related protein kinase 99 4e-20
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 99 4e-20
YDR477w [T] KOG0583 Serine/threonine protein kinase 99 4e-20
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 99 4e-20
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 99 4e-20
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 99 4e-20
Hs18677726 [T] KOG1151 Tousled-like protein kinase 99 4e-20
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 99 4e-20
Hs11140819 [T] KOG1151 Tousled-like protein kinase 99 4e-20
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 99 4e-20
At3g53930 [OUT] KOG0595 Serine/threonine-protein kinase involved... 99 4e-20
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 99 5e-20
Hs4505397 [T] KOG0198 MEKK and related serine/threonine protein ... 99 5e-20
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 99 5e-20
CE27768 [R] KOG0586 Serine/threonine protein kinase 99 5e-20
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 99 5e-20
CE23838 [R] KOG0586 Serine/threonine protein kinase 99 5e-20
CE19294 [T] KOG0198 MEKK and related serine/threonine protein ki... 99 5e-20
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 99 5e-20
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 5e-20
7302464 [R] KOG0586 Serine/threonine protein kinase 99 5e-20
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 99 7e-20
Hs21735544 [T] KOG0983 Mitogen-activated protein kinase (MAPK) k... 99 7e-20
Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases 99 7e-20
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 99 7e-20
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 99 7e-20
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 99 7e-20
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 99 7e-20
CE18454 [T] KOG4717 Serine/threonine protein kinase 99 7e-20
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 99 7e-20
7299438 [R] KOG0586 Serine/threonine protein kinase 99 7e-20
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 98 9e-20
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 98 9e-20
SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases 98 9e-20
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 98 9e-20
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 98 9e-20
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 98 9e-20
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 98 9e-20
Hs15277312 [R] KOG0584 Serine/threonine protein kinase 98 9e-20
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 98 9e-20
CE19898 [T] KOG0614 cGMP-dependent protein kinase 98 9e-20
CE19897 [T] KOG0614 cGMP-dependent protein kinase 98 9e-20
At3g22420 [R] KOG0584 Serine/threonine protein kinase 98 9e-20
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 9e-20
7300778 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 98 9e-20
Hs5579478 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 98 1e-19
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 98 1e-19
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 98 1e-19
CE02586 [T] KOG0696 Serine/threonine protein kinase 98 1e-19
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 1e-19
At3g23310 [R] KOG0605 NDR and related serine/threonine kinases 98 1e-19
At2g42550 [T] KOG0198 MEKK and related serine/threonine protein ... 98 1e-19
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 98 1e-19
SPBC543.07 [T] KOG0581 Mitogen-activated protein kinase kinase (... 97 2e-19
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 97 2e-19
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 97 2e-19
Hs4507719 [D] KOG0596 Dual specificity; serine/threonine and tyr... 97 2e-19
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 2e-19
Hs20547712 [D] KOG0596 Dual specificity; serine/threonine and ty... 97 2e-19
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 97 2e-19
At3g06630 [T] KOG0192 Tyrosine kinase specific for activated (GT... 97 2e-19
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 97 2e-19
At1g71530 [D] KOG0600 Cdc2-related protein kinase 97 2e-19
7294770 [T] KOG0603 Ribosomal protein S6 kinase 97 2e-19
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 97 2e-19
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 97 2e-19
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 97 2e-19
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 97 2e-19
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 97 2e-19
CE21401 [G] KOG0658 Glycogen synthase kinase-3 97 2e-19
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 97 2e-19
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 97 2e-19
CE15235 [R] KOG0589 Serine/threonine protein kinase 97 2e-19
At4g14350 [R] KOG0605 NDR and related serine/threonine kinases 97 2e-19
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 97 2e-19
>YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1579
Score = 1269 bits (3285), Expect = 0.0
Identities = 683/1396 (48%), Positives = 891/1396 (62%), Gaps = 79/1396 (5%)
Query: 202 AQQNGSTTTVNLTPTLSSPSIRXXXXXXXXXXXXFKPLQKQYVLNEQLYLSSMKNKKADD 261
+Q NGST++ L +++ S + + +KQYVLNEQLYL M+N+ DD
Sbjct: 211 SQPNGSTSSSTLQDIVTTNSSQRSVGHHGGSTTSLRTYKKQYVLNEQLYLRKMRNRANDD 270
Query: 262 YYTRGITSSGNEDDDD--FRVDGEND--------------DVDNDLSKLNNGLGSAIFGN 305
YYTRGI +S N +DD+ F GE+D D DND + FG
Sbjct: 271 YYTRGIVASSNFEDDEENFSNKGEDDLELEMDDLLKVEGEDKDNDFN----------FGY 320
Query: 306 NIATTTDKGFHSIDDDELVLMNDKILLERMEWLRSVEPNNPLIENSLNLLNKTGGSTDSL 365
N T++ K +++ +V M+ L +++WLR V + P +
Sbjct: 321 NFITSSTK-----NNENVVSMSLNYLKGKLDWLRDVNNDQPC-------------EIEDE 362
Query: 366 ESFSNIETQLALEQLSNNHLVRERLEWQTMLSSVLNGDIVKSEKTKLAKR-KPDEILLNH 424
E S + ++ L +L N +V R EWQTMLS VL GDIV++EKTK+A + K
Sbjct: 363 EWHSILGSEDLLSKLLQNPMVNNRFEWQTMLSKVLKGDIVRNEKTKIANQGKGPGFNTQF 422
Query: 425 NDLIWLELKAWLNGRTVEDQRKSLEYSKTTADEVFEEILNYXXXXXXXXXXXXXXAKILL 484
+D IW+ELKAW+NGRTVEDQ KSL + + D VF+EI+ + K L+
Sbjct: 423 SDDIWIELKAWMNGRTVEDQNKSLRIFRDSTDSVFQEIMAFKLEDNMSADEAAETIKSLV 482
Query: 485 NKYYKVVGYWKNLPNMNLEKPVTKTSNFVSRIEALNSLINSYEGLQYEIEALKQW-TQND 543
+KYY+V+ W N+ M+ EKP+TKT F +RI+ LNS +N I LK+W N
Sbjct: 483 DKYYRVLNLWPNIKRMHAEKPITKTEAFRNRIDTLNSWLNFKFNFDTNIAYLKKWIVGNK 542
Query: 544 DLDVTFTKDS----LDTEGIFK-NDRSFAEQIMKEKDIEGIFQKKIFFKHAPWMFKSKLV 598
+L+ T D+ LD +F N + FAEQIMKEKDIE IFQKKIFF APW+ K+K
Sbjct: 543 ELESTTEVDNTTVNLDDPAVFATNCKRFAEQIMKEKDIELIFQKKIFFPLAPWILKAKFF 602
Query: 599 FLKQQNSIHEMRLPLPVDKLHSLLTFPLRLIQEIISIRLEYARKLKKPTMMMIDQMIDDF 658
FLK Q + +E+ L L LL FP+RL+++II IRL YA+K++ PT+MMIDQM+DDF
Sbjct: 603 FLKYQKTWNELNLSYLDQDLEFLLMFPMRLVKDIILIRLSYAKKIQNPTLMMIDQMMDDF 662
Query: 659 STYIKLSVQIKHTLMEYRSGWSLKVEISDAFDAKVVEAIEFLFKLLHLKLIDSSKNSFKT 718
STYIKL+VQ+K T+ Y + W KV+I FD VVE +E+ F +L L+++ S KNSFKT
Sbjct: 663 STYIKLAVQMKFTVASYCNDWFFKVKIDPEFDHTVVEGLEYFFSILELRILYSGKNSFKT 722
Query: 719 FKEPDILFAHWENLKNFGCYISGASKVIAQGFVNITIRLLNRLHLYIMEEQRNSVDLVTS 778
KEPD+L +WE +N G YI A ++IA F +T+RL++RLH Y++ +Q L
Sbjct: 723 SKEPDLLLKYWEMFRNVGYYIDDAGELIAAEFTKLTLRLVHRLHAYLLRQQNTPPKLENE 782
Query: 779 DDARKWVVEVIENVGAFKRKTNRFSNVLTKAFQNSVLYNIKDHSMLLERLRNSGHFLIYT 838
A KW+V++ E +G+ KRK NRF+N+LTKAFQN V Y I+DH+ LL++L+ +GHFLIYT
Sbjct: 783 AAAEKWLVQIFEILGSMKRKLNRFTNILTKAFQNFVRYKIEDHNYLLKQLKETGHFLIYT 842
Query: 839 GGILEQNGIYLIASEELLGCSDDEIMDIIKSTKIGSDLIPKVEINNSLTIYNPPEDLTLP 898
GG LEQNG YLI S ELLGC DD+I+ IIK++ IG DL+PK+EINNSLTIYN +D
Sbjct: 843 GGYLEQNGTYLIGSPELLGCKDDDILRIIKNSDIGCDLVPKLEINNSLTIYNALDDNWNS 902
Query: 899 EAMFVQKERRNGVSYYHLKQDDLTQRVGIRG----KGGSSTAPXXXXXXLVQLENKLKML 954
+ +G +Y++K D TQ G + +LE +L L
Sbjct: 903 NSSLGSDISNDGTPFYYIKNDLTTQPRSYNGNRVNREPDFENSRSTEEEFYELETRLNSL 962
Query: 955 GYVLVFCPTKPMVWNGEMYNLTSEEPLTMEEFGLSVEEDVIVMLNQGSTYALDYQVDRFQ 1014
GYVLV P +P++W GEMYNL+ + + E L V + I ++ QGS+YAL+YQ DRFQ
Sbjct: 963 GYVLVLTPQEPLLWEGEMYNLSDNKTIKPEGLNLKVIPNSIDLMCQGSSYALEYQCDRFQ 1022
Query: 1015 HFAGDAISIREKKCAINSIETALQRINKSYFRMTYIVLKNFGSVQKNVTLQTNESVFFNI 1074
+G ++S EKK + +++ LQRINK+YFR TY VLKN+ + + + N
Sbjct: 1023 QISGSSVSFLEKKSSSETVKNNLQRINKAYFRCTYSVLKNYTKIVTTFKKVSPVNDLLNN 1082
Query: 1075 AYLFVKDFAKNFLLLNVATPETKAIIIRLMIQISIDWLTFVLDECDPANPETFRWCVPAM 1134
+LF +DF NFL +NVA E ++III LM+++SI WL F+ ++CDP + FRWCV +M
Sbjct: 1083 IFLFGRDFGLNFLRINVANNEKRSIIILLMMRLSIGWLKFLAEDCDPTDQRVFRWCVTSM 1142
Query: 1135 EFAMRMTNGWNXXXXXXXXXXXXXXXXARCMSLLISHFDITGARSREAERIDAQQTRPNF 1194
EFAM M +GWN + CMSLLISHFDI GARS E E+I+ QQ R N
Sbjct: 1143 EFAMHMVSGWNILALDECQFSSLKQKISECMSLLISHFDIIGARSIEVEKIN-QQARSNL 1201
Query: 1195 -XXXXXXXXMILAVNSEMRMNAITDMEKVVKVKRHYSVGKVIDDTDNQXXXXXXXXXXXX 1253
M+L VNSE R+ +I ++E+ +K H GKVIDD+D
Sbjct: 1202 DLEDVFDDDMMLQVNSEFRVQSIMELEERIKRNPH-QTGKVIDDSDKGNKYLVSLASSIS 1260
Query: 1254 XXXXRWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVME 1313
RWQKR+FIG G+FG VYSAV+LD G+ILAVKEI IQD+KSM++IFP +KEEM V+E
Sbjct: 1261 NVSMRWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLE 1320
Query: 1314 ILNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLAC 1373
ILNHPNIV YYGVEVHRDKVNIFME+CEG SLA+LLEHGRIEDEMVTQVYTLQLLEGLA
Sbjct: 1321 ILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAY 1380
Query: 1374 LHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLD-------------- 1419
LH+SG+VHRD+KPENILLD NGVIKYVDFGAAK IA NG++ S++
Sbjct: 1381 LHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTH 1440
Query: 1420 ------ANNKSTGGKDMIGTPMYMAPETVTGQ-GHGKFGSDDIWSLGCVVLEMVTGRRPW 1472
N DM+GTPMYMAPE++TG GK G+DD+WSLGCVVLEM+TGRRPW
Sbjct: 1441 VSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPW 1500
Query: 1473 ANLDNEWAIMYHVAAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
ANLDNEWAIMYHVAAGH PQFPTK E+SSAG KF+ RCLIQ+ +KRA+A+ELL+DPWI Q
Sbjct: 1501 ANLDNEWAIMYHVAAGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAVELLMDPWIVQ 1560
Query: 1533 IRNIAFGGNAESFNNE 1548
IR IAFG ++ S + E
Sbjct: 1561 IREIAFGDDSSSTDTE 1576
>YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1331
Score = 1088 bits (2813), Expect = 0.0
Identities = 558/1186 (47%), Positives = 779/1186 (65%), Gaps = 27/1186 (2%)
Query: 378 EQLSNNHLVRERLEWQTMLSSVLNGDIVKSEKTKLAKR-KPDEILLNHNDLIWLELKAWL 436
++L+ N + ER +WQ+ML+ VL GDIVK EKT++A + K + +D IWLELKAWL
Sbjct: 141 DELAWNEIATERFKWQSMLARVLKGDIVKGEKTRIANQVKKPGLNKELSDEIWLELKAWL 200
Query: 437 NGRTVEDQRKSLEYSKTTADEVFEEILNYXXXXXXXXXXXXXXAKI--LLNKYYKVVGYW 494
NGRT+++ +SL Y + ++D VFEEI+ + A + L+N+Y+ VV YW
Sbjct: 201 NGRTMQEMEQSLTYLRDSSDSVFEEIMKFQIPQGKILSLDALEAILQDLMNRYHSVVSYW 260
Query: 495 KNLPNMNLEKPVTKTSNFVSRIEALNSLINSYEGLQYEIEALKQWTQNDDLDVTFTKDSL 554
NL M +KP+T T+ F +RI+ +NS +N L + L W +
Sbjct: 261 PNLKKMYKDKPITNTAEFTARIDVMNSWLNFKTNLTLRRQELDDWINRFSPISSSDNCQE 320
Query: 555 DTEGIFKND---RSFAEQIMKEKDIEGIFQKKIFFKHAPWMFKSKLVFLKQQNSIHEMRL 611
D +G+ + + + AEQ+MKEK+IE IFQKKIF+ +PWMFK KL F+ + ++ +M +
Sbjct: 321 DFDGVPQWNCKMKILAEQLMKEKNIESIFQKKIFYPLSPWMFKLKLHFIVYRETLTKMNI 380
Query: 612 PLPVDKLHSLLTFPLRLIQEIISIRLEYARKLKKPTMMMIDQMIDDFSTYIKLSVQIKHT 671
P ++L SLL FP+ LI+E+I RL YARKLK PTMMMIDQMIDDF+ +I+LSVQ+K+T
Sbjct: 381 KYPYERLRSLLAFPVYLIKEVILTRLSYARKLKNPTMMMIDQMIDDFNAFIRLSVQLKYT 440
Query: 672 LMEYRSGWSLKVEISDAFDAKVVEAIEFLFKLLHLKLIDSSKNSFKTFKEPDILFAHWEN 731
L +Y S V+ F+ V+EAI +LF LL+LKLIDSSK +FK PD+L +W++
Sbjct: 441 LTKYCSNLPFDVDFDPTFENTVIEAIRYLFFLLNLKLIDSSKQNFKA---PDLLLKYWDH 497
Query: 732 LKNFGCYISGASKVIAQGFVNITIRLLNRLHLYIMEEQRNSVDLVTSDDARKWVVEVIEN 791
LKN G YI+GA VI F+ +T+RL+++L Y++++Q + +A KW+ + EN
Sbjct: 498 LKNTGHYINGAETVIPNEFLKLTLRLVHKLQFYLLKQQNFPPTFANASEAEKWLSSIFEN 557
Query: 792 VGAFKRKTNRFSNVLTKAFQNSVLYNIKDHSMLLERLRNSGHFLIYTGGILEQNGIYLIA 851
+GA KRK NRFSN+L KAFQNS +Y I ++ L+++L+++ +FL+Y+G E +G+Y+ A
Sbjct: 558 LGAMKRKLNRFSNILVKAFQNSAVYQINHNAQLVKKLKDAHYFLVYSGNTFESSGVYMFA 617
Query: 852 SEELLGCSDDEIMDIIKSTKIGSDLIPKVEINNSLTIYNPPEDLTLPEAMFVQKERRNGV 911
+ ELLGC +D I+ I+++ IG DL+PK++I N+L +Y+ T + + E G+
Sbjct: 618 APELLGCDNDTILRILRNKSIGCDLVPKLDIGNNLNVYDITTKETDLNILVSKGEDSKGI 677
Query: 912 SYYHL---KQDDLTQRVGIRGKGGSSTAPXXXXXX-----LVQLENKLKMLGYVLVFCPT 963
YY + DL + K ST P + +LE L LG ++V P
Sbjct: 678 PYYRVVANSSSDLDRHAHQSKKKNFSTDPFDQHLDEKNNEVFELEVALSSLGALVVLYPG 737
Query: 964 KPMVWNGEMYNLTSEEPLTMEEFGLSV--EEDVIVMLNQGSTYALDYQVDRFQHFAGDAI 1021
+P+VW+G +Y L E L + +++LNQGS YAL YQ+D+F GD++
Sbjct: 738 EPVVWDGPVYKLPGNNLFASNEMDLGKIGNPNTLILLNQGSNYALTYQIDKFNQTVGDSV 797
Query: 1022 SIREKKCAINSIETALQRINKSYFRMTYIVLKNFGSVQKNVTLQTNESVFFNIAYLFVKD 1081
S EK+C++NSIE++LQ+INK+Y+++TY VL N+ + + Q + N ++F +D
Sbjct: 798 SFIEKRCSLNSIESSLQKINKAYYKLTYTVLNNYKGILGSFMKQCPGNELLNSIFMFGRD 857
Query: 1082 FAKNFLLLNVATPETKAIIIRLMIQISIDWLTFVLDECDPANPETFRWCVPAMEFAMRMT 1141
F ++FL N + + K +II LM+++ ++WL F+++ECDP + TFRWCV AM+FAM+MT
Sbjct: 858 FGRSFLKYNAFSSKRKYVIIFLMVKLGMNWLKFLVEECDPTDQRTFRWCVLAMDFAMQMT 917
Query: 1142 NGWNXXXXXXXXXXXXXXXXARCMSLLISHFDITGARSREAERIDAQQTRPNFXXXXXXX 1201
+G+N + CMSLLISHFD+ GAR+ EAE QQ R N
Sbjct: 918 SGYNILALNVKQFQELKERVSVCMSLLISHFDVMGARATEAEN-GMQQARLNIDTEENID 976
Query: 1202 X-MILAVNSEMRMNAITDMEKVVKVKRHYSVGKVIDDTDNQXXXXXXXXXXXXXXXXRWQ 1260
L +NS +R+ AI +EK +K + +GKV+D TD RWQ
Sbjct: 977 EEATLEINSRLRLEAIKTLEKTMK-RNPRQMGKVLDATDQGNKYLLSLASSLSNVSMRWQ 1035
Query: 1261 KRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNI 1320
KRSFIG G+FG VYSA+NL+ G+ILAVKEIKI D +MK+IFP +KEEM V+E+LNHPNI
Sbjct: 1036 KRSFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNI 1095
Query: 1321 VQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVV 1380
VQYYGVEVHRDKVNIFME+CEG SLASLL+HGRIEDEMVTQVYT +LLEGLA LHQSGVV
Sbjct: 1096 VQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVV 1155
Query: 1381 HRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRIS----LDANNKSTGGKDMIGTPMY 1436
HRDIKPENILLD NG+IKYVDFG A+ + + ++ + D ++ +M+GTPMY
Sbjct: 1156 HRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMY 1215
Query: 1437 MAPETVTGQG-HGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPT 1495
MAPET++G GK G+DD+W+LGCVVLEM TGRRPW+NLDNEWAIMYHVAAG +PQ P
Sbjct: 1216 MAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPN 1275
Query: 1496 KSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNIAFGGN 1541
+ E+++AGR F+ RCL+QD RATA+ELL+DPW+ QIR IAFG +
Sbjct: 1276 RDEMTAAGRAFLERCLVQDPTMRATAVELLIDPWMIQIREIAFGNS 1321
>SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1401
Score = 406 bits (1043), Expect = e-112
Identities = 216/598 (36%), Positives = 334/598 (55%), Gaps = 20/598 (3%)
Query: 947 LENKLKMLGYVLVFCPTKPMVWNGEMYNLTSEEPLTMEEFGLSVEEDVIVMLNQGSTYAL 1006
LE + YVL+ CP P+VW G + E + + +F + ++ + + ++ L
Sbjct: 723 LETIQQNCSYVLILCPVHPIVWKGRI------EKVDVPDFSVDLKTNRVRIIASNKREHL 776
Query: 1007 DYQVDRFQHFAGDAISIR-EKKCAINSIETALQRINKSYFRMTYIVLKNFGSVQKNVTLQ 1065
FQ +GD +++ E + +I + R++K R++ V+ +V++ +
Sbjct: 777 QAAKSVFQSISGDLVTLAVECRSSITRVYKEFIRLSKLCMRISSTVVDCVSAVREACSGV 836
Query: 1066 TNESVFFNIAYLFVKDFAKNFLLLNVATPETKAIIIRLMIQISIDWLTFVLDECDPANPE 1125
+ +++ + F +F + L + + R + ++++W++F+ DECD + +
Sbjct: 837 NCHDLIYHV-FSFAAEFGQRILRFLSFDSYWQTKLKRKITSLAVEWISFICDECDLMDRK 895
Query: 1126 TFRWCVPAMEFAMRMTNGWNXXXXXXXXXXXXXXXXARCMSLLISHFDITGARSREAERI 1185
TFRW V A+EF M M G N + M+ L++HFD+ GA+S+ A ++
Sbjct: 896 TFRWGVGALEFLMLMIRGNNILLIDDAMFLKIREKVGKSMAFLLTHFDVLGAKSKVAAKL 955
Query: 1186 DAQQTRPNFXXXXXX---------XXMILAVNSEMRMNAITDMEKVVKVKRHYSVGKVID 1236
+ T + +L + +R++ + ++E+ + ++G V+D
Sbjct: 956 QRESTEVSSSPRLTSFGDVEEEALSIQLLQKETMLRIDEL-EIERNNTLLERLAIGHVLD 1014
Query: 1237 DTDNQXXXXXXXXXXXXXXXXRWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAK 1296
D+ + RWQ+ F+ SG FG VY+ VN++TGD+LAVKEIK+QD++
Sbjct: 1015 DSVFRNRDFIKLASSFSNITIRWQQGHFVRSGMFGDVYTGVNMETGDLLAVKEIKLQDSR 1074
Query: 1297 SMKQIFPSLKEEMRVMEILNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIED 1356
+ + + EM V+E LNHPN+V YYGVEVHR+KV IFMEFC+G SLA LL HGRIED
Sbjct: 1075 TFRSTVDQIHNEMTVLERLNHPNVVTYYGVEVHREKVYIFMEFCQGGSLADLLAHGRIED 1134
Query: 1357 EMVTQVYTLQLLEGLACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRI 1416
E V +VY +QLLEGLA +H ++HRDIKP NILLD G+IKY DFG+A ++ +
Sbjct: 1135 ENVLKVYVVQLLEGLAYIHSQHILHRDIKPANILLDHRGMIKYSDFGSALYVSPPTDPEV 1194
Query: 1417 SLDANNKSTGGKDMIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLD 1476
+ + + GTPMYMAPE + G G FG+ DIWSLGCV+LEM+TG PW+ +D
Sbjct: 1195 RYEDIQPEL--QHLAGTPMYMAPEIILGTKKGDFGAMDIWSLGCVILEMMTGSTPWSEMD 1252
Query: 1477 NEWAIMYHVAAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIR 1534
NEWAIMYHVAA H P P +ISS R FI +C +D +R A++LL PWI+ R
Sbjct: 1253 NEWAIMYHVAAMHTPSIPQNEKISSLARDFIEQCFERDPEQRPRAVDLLTHPWITDFR 1310
Score = 241 bits (616), Expect = 5e-63
Identities = 159/546 (29%), Positives = 277/546 (50%), Gaps = 17/546 (3%)
Query: 315 FHSIDDDELVLMNDKILLERMEWLRSVEPNNPLIENSLNLLNKTGGSTDSLESFSNIETQ 374
F++ID D + +DK L + L E + S N +++ ++ F +
Sbjct: 171 FNNIDQDSI---SDKSLPSTNQSLHHSEEDT----ESDNDFSESIHPEFDIDVFYKVSNI 223
Query: 375 LALEQLSNNHLVRERLEWQTMLSSVLNGDIVKSEKTKLAKRKPDEILLNHNDLIWLELKA 434
L E + RERLEW +MLSSVL GD++++EK +L +PD + +WL L+A
Sbjct: 224 LYDESDLQDPEKRERLEWHSMLSSVLKGDVMQTEKRRLRLTEPDGHSGTYISEVWLGLQA 283
Query: 435 WLNGRTVEDQRKSLEYSKTTADEVFEEILNYXXXXXXXXXXXXXXAKILLNKYYKVVGYW 494
WL+GR DQ + + S+ + V E++++ +L K + ++
Sbjct: 284 WLHGRLNADQAEVIRKSREGVEPVLREVIDFQIQDEETTKPPLEQVTEILEKVEQCKQFY 343
Query: 495 KNLPNMNLEKPVTKTSNFVSRIEALNSLINSYEGLQYEIEALKQWTQNDDLDVTFTKDSL 554
+ M P++ + F ++ AL S N E +Q E L++W ND+ D+T
Sbjct: 344 ISSREMEENVPLSASKEFNYKLNALISWSNVMESIQVETLVLQKWVGNDEFDLTMRTPQF 403
Query: 555 DTEGIFKNDRSFAEQIMKEKDIEGIFQKKIFFKHAPWMFKSKLVFLKQQNSIHEMRLPLP 614
+ +G+ +N SF E+I ++ ++ F+++ + ++K + + EM+LP
Sbjct: 404 NYDGV-ENTSSFVERIFRQSGLQRTFEQRTLTTLNRIIHQAKQTISENAQAFEEMKLPTY 462
Query: 615 VDKLHSLLTFPLRLIQEIISIRLEYARKLKKPTMMMIDQMIDDFSTYIKLSVQIKHTLME 674
DKL L+ FP++L++E + +RL YA+K+K P +++D M+DDF + ++V+IK ++
Sbjct: 463 EDKLLPLVRFPIKLLEEALRLRLAYAKKIKGPNFLIVDSMLDDFKIALSVAVRIKREYIK 522
Query: 675 YRS---GWSLKVEISDAFDAKVVEAIEFLFKLLHLKLIDSSKNSFKTFKEPDILFAHWEN 731
S GWSL + + +D ++++++F FKLL LKL +KN + FKE D L W
Sbjct: 523 IASPSPGWSLPTNVDEDYDNVLLDSLKFYFKLLTLKLSSGNKNLY--FKEIDFLENEWAF 580
Query: 732 LKNFGCYISGASKVIAQGFVNITIRLLNRLHLYIMEEQRNSVDLVTSDDARKWVVEVIEN 791
L +I+G +A F ++ LL +H Y+ E N T+ W +++N
Sbjct: 581 LNEHIYWINGGDIHMAGQFSYLSNSLLLNVHRYV-ESHLNGPTERTAASLTNWYSTLLKN 639
Query: 792 VGAFKRKTNRFSNVLTKAFQNSVLYNIKDHSM--LLERLRNSGHFLIYTGGILEQNGIYL 849
RK RFS L F+N+ + I + + L+ RL +GHFL YT LE++G+++
Sbjct: 640 TQIRFRKILRFSETLNSRFENASDFVISEGHLPDLVNRLSTTGHFLAYTAN-LERDGVFV 698
Query: 850 IASEEL 855
IA L
Sbjct: 699 IADHTL 704
>Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1558
Score = 212 bits (539), Expect = 4e-54
Identities = 112/273 (41%), Positives = 175/273 (64%), Gaps = 23/273 (8%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQ--DAKSMKQIFPSLKEEMRVMEIL 1315
+WQ+ + IG G +G VY+ +++DTG+++A+KEI+ Q D K++K+ +E+++ E +
Sbjct: 1292 KWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKET----ADELKIFEGI 1347
Query: 1316 NHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLH 1375
HPN+V+Y+GVE+HR+++ IFME+C+ +L + G E V ++Y+ Q+ + LH
Sbjct: 1348 KHPNLVRYFGVELHREEMYIFMEYCDEGTLEEVSRLGL--QEHVIRLYSKQITIAINVLH 1405
Query: 1376 QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
+ G+VHRDIK NI L +G+IK DFG + + KN ++ + + N+ +GT
Sbjct: 1406 EHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKL-KNNAQTMPGEVNST-------LGTAA 1457
Query: 1436 YMAPETVT---GQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQ 1492
YMAPE +T G+GHG+ + DIWSLGCVV+EMVTG+RPW ++ + IMY V GH P
Sbjct: 1458 YMAPEVITRAKGEGHGR--AADIWSLGCVVIEMVTGKRPWHEYEHNFQIMYKVGMGHKPP 1515
Query: 1493 FPTKSEISSAGRKFISRCLIQDANKRATAMELL 1525
P + +S G+ F+S CL D R TA +LL
Sbjct: 1516 IPER--LSPEGKDFLSHCLESDPKMRWTASQLL 1546
>Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1607
Score = 212 bits (539), Expect = 4e-54
Identities = 112/273 (41%), Positives = 175/273 (64%), Gaps = 23/273 (8%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQ--DAKSMKQIFPSLKEEMRVMEIL 1315
+WQ+ + IG G +G VY+ +++DTG+++A+KEI+ Q D K++K+ +E+++ E +
Sbjct: 1341 KWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKET----ADELKIFEGI 1396
Query: 1316 NHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLH 1375
HPN+V+Y+GVE+HR+++ IFME+C+ +L + G E V ++Y+ Q+ + LH
Sbjct: 1397 KHPNLVRYFGVELHREEMYIFMEYCDEGTLEEVSRLGL--QEHVIRLYSKQITIAINVLH 1454
Query: 1376 QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
+ G+VHRDIK NI L +G+IK DFG + + KN ++ + + N+ +GT
Sbjct: 1455 EHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKL-KNNAQTMPGEVNST-------LGTAA 1506
Query: 1436 YMAPETVT---GQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQ 1492
YMAPE +T G+GHG+ + DIWSLGCVV+EMVTG+RPW ++ + IMY V GH P
Sbjct: 1507 YMAPEVITRAKGEGHGR--AADIWSLGCVVIEMVTGKRPWHEYEHNFQIMYKVGMGHKPP 1564
Query: 1493 FPTKSEISSAGRKFISRCLIQDANKRATAMELL 1525
P + +S G+ F+S CL D R TA +LL
Sbjct: 1565 IPER--LSPEGKDFLSHCLESDPKMRWTASQLL 1595
>At1g54960 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 585
Score = 209 bits (531), Expect = 4e-53
Identities = 118/280 (42%), Positives = 163/280 (58%), Gaps = 17/280 (6%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQI----FPSLKEEMRVME 1313
RW+K IG G+FGTVY +NLD+G++LAVK++ I + K+ L+EE+++++
Sbjct: 67 RWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLK 126
Query: 1314 ILNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLAC 1373
L+HPNIV+Y G + +NI +EF G S++SLLE E V + YT QLL GL
Sbjct: 127 NLSHPNIVRYLGTVREDETLNILLEFVPGGSISSLLEKFGAFPESVVRTYTNQLLLGLEY 186
Query: 1374 LHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGT 1433
LH ++HRDIK NIL+D G IK DFGA+K +A+ + +G K M GT
Sbjct: 187 LHNHAIMHRDIKGANILVDNQGCIKLADFGASKQVAELAT----------ISGAKSMKGT 236
Query: 1434 PMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQF 1493
P +MAPE + GH S DIWS+GC V+EMVTG+ PW+ E A ++H+
Sbjct: 237 PYWMAPEVILQTGHS--FSADIWSVGCTVIEMVTGKAPWSQQYKEIAAIFHIGTTK-SHP 293
Query: 1494 PTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQI 1533
P ISS F+ +CL Q+ N R TA ELL W + I
Sbjct: 294 PIPDNISSDANDFLLKCLQQEPNLRPTASELLKVKWSTDI 333
>7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1612
Score = 208 bits (530), Expect = 5e-53
Identities = 116/273 (42%), Positives = 169/273 (61%), Gaps = 21/273 (7%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
RW + IG G FG VY+AVN +TG+++A+KEI IQ ++ + ++ EE++++E + H
Sbjct: 1322 RWHRGIKIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGET--RALKNVAEELKILEGIKH 1379
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
N+V+YYG+EVHR+++ IFME C +L SL+E E +T+ +T QLL G++ LH+
Sbjct: 1380 KNLVRYYGIEVHREELLIFMELCSEGTLESLVELTGNLPEALTRRFTAQLLSGVSELHKH 1439
Query: 1378 GVVHRDIKPENI-LLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGG-KDMIGTPM 1435
G+VHRDIK NI L+D + +K DFG+A + + A+ G + +GT
Sbjct: 1440 GIVHRDIKTANIFLVDGSNSLKLGDFGSA----------VKIQAHTTVPGELQGYVGTQA 1489
Query: 1436 YMAPETVT---GQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQ 1492
YMAPE T GHG+ + DIWS+GCVV+EM +G+RPWA D+ + IM+ V G PQ
Sbjct: 1490 YMAPEVFTKTNSDGHGR--AADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQ 1547
Query: 1493 FPTKSEISSAGRKFISRCLIQDANKRATAMELL 1525
P +S G FI CL D +R TA+ELL
Sbjct: 1548 AP--ESLSQEGHDFIDHCLQHDPKRRLTAVELL 1578
>At1g09000 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 666
Score = 202 bits (514), Expect = 3e-51
Identities = 115/276 (41%), Positives = 161/276 (57%), Gaps = 17/276 (6%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQI----FPSLKEEMRVMEI 1314
W+K IG G+FGTVY +NLD+G++LAVK++ I + K+ L+EE+++++
Sbjct: 69 WRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKN 128
Query: 1315 LNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACL 1374
L+HPNIV+Y G D +NI +EF G S++SLLE E V + YT QLL GL L
Sbjct: 129 LSHPNIVRYLGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYL 188
Query: 1375 HQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
H ++HRDIK NIL+D G IK DFGA+K +A+ + TG K M GTP
Sbjct: 189 HNHAIMHRDIKGANILVDNKGCIKLADFGASKQVAELAT----------MTGAKSMKGTP 238
Query: 1435 MYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFP 1494
+MAPE + GH S DIWS+GC V+EMVTG+ PW+ E A ++ + P
Sbjct: 239 YWMAPEVILQTGHS--FSADIWSVGCTVIEMVTGKAPWSQQYKEVAAIFFIGTTK-SHPP 295
Query: 1495 TKSEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+SS + F+ +CL + N R TA ELL P++
Sbjct: 296 IPDTLSSDAKDFLLKCLQEVPNLRPTASELLKHPFV 331
>At3g06030 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 651
Score = 201 bits (511), Expect = 8e-51
Identities = 112/278 (40%), Positives = 165/278 (59%), Gaps = 17/278 (6%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQI----FPSLKEEMRVME 1313
RW+K IG G+FG VY +NLD+G++LA+K++ I + + K+ L+EE+++++
Sbjct: 67 RWRKGELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLLK 126
Query: 1314 ILNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLAC 1373
L+HPNIV+Y G D +NI MEF G S++SLLE E V +YT QLL GL
Sbjct: 127 NLSHPNIVRYLGTVRESDSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLLLGLEY 186
Query: 1374 LHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGT 1433
LH +G++HRDIK NIL+D G I+ DFGA+K K + L N G K M GT
Sbjct: 187 LHNNGIMHRDIKGANILVDNKGCIRLADFGASK-------KVVELATVN---GAKSMKGT 236
Query: 1434 PMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQF 1493
P +MAPE + GH S DIWS+GC V+EM TG+ PW+ ++A + H+
Sbjct: 237 PYWMAPEVILQTGHS--FSADIWSVGCTVIEMATGKPPWSEQYQQFAAVLHIGRTKAHP- 293
Query: 1494 PTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWIS 1531
P ++S + F+ +CL ++ + R +A ELL P+++
Sbjct: 294 PIPEDLSPEAKDFLMKCLHKEPSLRLSATELLQHPFVT 331
>SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 362
Score = 184 bits (466), Expect = 1e-45
Identities = 109/281 (38%), Positives = 163/281 (57%), Gaps = 21/281 (7%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMK----QIFPSLKEEMRVME 1313
+W + + IGSGSFG VY +N +G+++AVK++ + K ++ +L E+ +++
Sbjct: 96 KWIRGALIGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQ 155
Query: 1314 ILNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLE-HGRIEDEMVTQVYTLQLLEGLA 1372
L+H +IVQY G ++ D +NIF+E+ G S+A LL +G E+ +V + Q L+GL
Sbjct: 156 ELSHEHIVQYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKN-FIKQTLKGLE 214
Query: 1373 CLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGG--KDM 1430
LH G+VHRDIK NIL+D G IK DFG SK++ L++ + TGG
Sbjct: 215 YLHSRGIVHRDIKGANILVDNKGKIKISDFGI--------SKKLELNSTSTKTGGARPSF 266
Query: 1431 IGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHL 1490
G+ +MAPE V H + DIWSLGC+V+EM+T + P+ N D AI + + L
Sbjct: 267 QGSSFWMAPEVVKQTMHTE--KTDIWSLGCLVIEMLTSKHPYPNCDQMQAI-FRIGENIL 323
Query: 1491 PQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWIS 1531
P+FP S ISS+ F+ + D N R TA ELL P++S
Sbjct: 324 PEFP--SNISSSAIDFLEKTFAIDCNLRPTASELLSHPFVS 362
>At1g53570 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 184 bits (466), Expect = 1e-45
Identities = 108/280 (38%), Positives = 155/280 (54%), Gaps = 17/280 (6%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIK-IQDAKSMKQIFPSLKEEMRVMEILNH 1317
W+K F+GSG+FG VY N + G + A+KE+K I D ++ K+ L +E+ ++ L H
Sbjct: 214 WKKGKFLGSGTFGQVYLGFNSEKGKMCAIKEVKVISDDQTSKECLKQLNQEINLLNQLCH 273
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
PNIVQYYG E+ + +++++E+ G S+ LL+ E V Q YT Q+L GLA LH
Sbjct: 274 PNIVQYYGSELSEETLSVYLEYVSGGSIHKLLKDYGSFTEPVIQNYTRQILAGLAYLHGR 333
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
VHRDIK NIL+D NG IK DFG AK + S +S G+P +M
Sbjct: 334 NTVHRDIKGANILVDPNGEIKLADFGMAKHVTA-FSTMLSFK------------GSPYWM 380
Query: 1438 APETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKS 1497
APE V Q +G + DIWSLGC +LEM T + PW+ + AI + P+ P
Sbjct: 381 APEVVMSQ-NGYTHAVDIWSLGCTILEMATSKPPWSQFEGVAAIFKIGNSKDTPEIP--D 437
Query: 1498 EISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNIA 1537
+S+ + FI CL ++ R TA +LL P++ +A
Sbjct: 438 HLSNDAKNFIRLCLQRNPTVRPTASQLLEHPFLRNTTRVA 477
>YJL095w [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1478
Score = 180 bits (457), Expect = 1e-44
Identities = 108/279 (38%), Positives = 162/279 (57%), Gaps = 22/279 (7%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPS----LKEEMRVMEI 1314
W K IG GSFG VY +N+ TG+++AVK++++ S + S L+ E+ ++
Sbjct: 1175 WMKGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKD 1234
Query: 1315 LNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLE-HGRIEDEMVTQVYTLQLLEGLAC 1373
L+H NIVQY G E + ++F+E+ G S+ SL+ +GR ++ ++ + T Q+L+GLA
Sbjct: 1235 LDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHL-TTQVLKGLAY 1293
Query: 1374 LHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGT 1433
LH G++HRD+K +N+LLD++G+ K DFG ++ K + +N+ T M GT
Sbjct: 1294 LHSKGILHRDMKADNLLLDQDGICKISDFGISR-------KSKDIYSNSDMT----MRGT 1342
Query: 1434 PMYMAPETV-TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQ 1492
+MAPE V T QG+ DIWSLGC+VLEM G+RPW+NL+ A+ + P
Sbjct: 1343 VFWMAPEMVDTKQGYS--AKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPP 1400
Query: 1493 FP--TKSEISSAGRKFISRCLIQDANKRATAMELLLDPW 1529
P T IS GR F+ C + KR TA ELL P+
Sbjct: 1401 IPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPF 1439
>At4g08500 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 179 bits (453), Expect = 4e-44
Identities = 109/289 (37%), Positives = 161/289 (54%), Gaps = 22/289 (7%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQ-IFPSLKEEMRVMEILNH 1317
WQK +G GSFG+VY ++ D GD AVKE+ + D S Q L+ E++++ L H
Sbjct: 333 WQKGQLLGRGSFGSVYEGISGD-GDFFAVKEVSLLDQGSQAQECIQQLEGEIKLLSQLQH 391
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
NIV+Y G + IF+E SL L + ++ D +V+ +YT Q+L+GL LH
Sbjct: 392 QNIVRYRGTAKDGSNLYIFLELVTQGSLLKLYQRYQLRDSVVS-LYTRQILDGLKYLHDK 450
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
G +HRDIK NIL+D NG +K DFG AK+ +K K GTP +M
Sbjct: 451 GFIHRDIKCANILVDANGAVKLADFGLAKV--------------SKFNDIKSCKGTPFWM 496
Query: 1438 APETVTGQGHGKFGSD-DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTK 1496
APE + + +GS DIWSLGC VLEM TG+ P+++L+ A ++ + G LP+ P
Sbjct: 497 APEVINRKDSDGYGSPADIWSLGCTVLEMCTGQIPYSDLEPVQA-LFRIGRGTLPEVP-- 553
Query: 1497 SEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ-IRNIAFGGNAES 1544
+S R FI +CL + +R TA ELL P++ + + ++ GG+ +
Sbjct: 554 DTLSLDARLFILKCLKVNPEERPTAAELLNHPFVRRPLPSVGSGGSGSA 602
>At1g63700 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 883
Score = 174 bits (440), Expect = 1e-42
Identities = 108/295 (36%), Positives = 157/295 (52%), Gaps = 23/295 (7%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKI-QDAKSMKQIFPSLKEEMRVMEILN 1316
RW+K +G GSFG VY N ++G++ A+KE+ + D ++ L +E+ V+ L
Sbjct: 399 RWKKGRLLGMGSFGHVYLGFNSESGEMCAMKEVTLCSDDPKSRESAQQLGQEISVLSRLR 458
Query: 1317 HPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLL-EHGRIEDEMVTQVYTLQLLEGLACLH 1375
H NIVQYYG E DK+ I++E+ G S+ LL E+G+ + + YT Q+L GLA LH
Sbjct: 459 HQNIVQYYGSETVDDKLYIYLEYVSGGSIYKLLQEYGQFGENAIRN-YTQQILSGLAYLH 517
Query: 1376 QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
VHRDIK NIL+D +G +K DFG AK I +G G+P
Sbjct: 518 AKNTVHRDIKGANILVDPHGRVKVADFGMAKHI-------------TAQSGPLSFKGSPY 564
Query: 1436 YMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPT 1495
+MAPE + +G + DIWSLGC VLEM T + PW+ + A+ + LP P
Sbjct: 565 WMAPEVIK-NSNGSNLAVDIWSLGCTVLEMATTKPPWSQYEGVPAMFKIGNSKELPDIP- 622
Query: 1496 KSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQI----RNIAFGGNAESFN 1546
+S G+ F+ +CL ++ R TA +LL ++ + R I G AE+ N
Sbjct: 623 -DHLSEEGKDFVRKCLQRNPANRPTAAQLLDHAFVRNVMPMERPIVSGEPAEAMN 676
>SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1116
Score = 173 bits (438), Expect = 2e-42
Identities = 98/281 (34%), Positives = 158/281 (55%), Gaps = 18/281 (6%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDA------KSMKQIFPSLKEEMRV 1311
+W K IG+G++G V+ A+N++TG+++AVK+++I + K I S+ E+ +
Sbjct: 824 KWMKGELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGRHDQLRKDIVDSINAEISM 883
Query: 1312 MEILNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGL 1371
+ L+H NIVQY G E ++IF+E+ G S+ L + +E + + + Q+L GL
Sbjct: 884 IADLDHLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLRNYGPFEEQLVRFVSRQVLYGL 943
Query: 1372 ACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMI 1431
+ LH G++HRD+K +N+L+D +GV K DFG I+K+ DAN M
Sbjct: 944 SYLHSKGIIHRDLKADNLLIDFDGVCKISDFG----ISKHSDNVYDNDAN------LSMQ 993
Query: 1432 GTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLP 1491
G+ +MAPE + G D+WSLGCVVLEM+ GRRPW+ + A+ P
Sbjct: 994 GSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEMLAGRRPWSTDEAIQAMFKLGTEKKAP 1053
Query: 1492 QFPTK--SEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
P++ S++S +F++ C +A+ R TA ELL P++
Sbjct: 1054 PIPSELVSQVSPEAIQFLNACFTVNADVRPTAEELLNHPFM 1094
>SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1062
Score = 171 bits (433), Expect = 8e-42
Identities = 98/267 (36%), Positives = 152/267 (56%), Gaps = 23/267 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G G+FG VY +N+ G+ +AVK++K+ +K +K +K E+ +++ L+HPNIV+Y
Sbjct: 15 LGKGAFGAVYRGLNIKNGETVAVKKVKL--SKMLKSDLSVIKMEIDLLKNLDHPNIVKYR 72
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEH-GRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
G D + I +E+CE SL S+ ++ G+I + +V +YT Q+L+GL LH GV+HRD
Sbjct: 73 GSYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVA-LYTFQVLQGLLYLHNQGVIHRD 131
Query: 1384 IKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVT 1443
IK NIL ++G IK DFG A I + ++G+P +MAPE +
Sbjct: 132 IKGANILTTKDGTIKLADFGVATKI--------------NALEDHSVVGSPYWMAPEVI- 176
Query: 1444 GQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAG 1503
+ G + DIWS+GC V+E++ G P+ +LD A+ V H P S ISSA
Sbjct: 177 -ELVGATTASDIWSVGCTVIELLDGNPPYYDLDPTSALFRMVKDEHP---PLPSNISSAA 232
Query: 1504 RKFISRCLIQDANKRATAMELLLDPWI 1530
+ F+ +C +D N R +LL PW+
Sbjct: 233 KSFLMQCFQKDPNLRIKTRKLLKHPWV 259
>Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 626
Score = 168 bits (425), Expect = 7e-41
Identities = 103/270 (38%), Positives = 156/270 (57%), Gaps = 17/270 (6%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQ-DAKSMKQIFPSLKEEMRVMEILNH 1317
W++ +G G+FG VY ++DTG LA K+++ D+ + +L+ E+++++ L H
Sbjct: 362 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQH 421
Query: 1318 PNIVQYYGVEVHRDK--VNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLH 1375
IVQYYG R + + IFME+ G S+ L+ E VT+ YT Q+LEG++ LH
Sbjct: 422 ERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLH 481
Query: 1376 QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
+ +VHRDIK NIL D G +K DFGA+K + + I + TG + + GTP
Sbjct: 482 SNMIVHRDIKGANILRDSAGNVKLGDFGASKRL-----QTICM----SGTGMRSVTGTPY 532
Query: 1436 YMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPT 1495
+M+PE ++G+G+G+ D+WSLGC V+EM+T + PWA + AI PQ P
Sbjct: 533 WMSPEVISGEGYGR--KADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLP- 589
Query: 1496 KSEISSAGRKFISRCLIQDANKRATAMELL 1525
S IS GR F+ R + +A +R +A ELL
Sbjct: 590 -SHISEHGRDFLRRIFV-EARQRPSAEELL 617
>At4g08480 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 773
Score = 163 bits (413), Expect = 2e-39
Identities = 102/274 (37%), Positives = 149/274 (54%), Gaps = 21/274 (7%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQ-IFPSLKEEMRVMEILNH 1317
WQK + GSFG+VY A++ D GD AVKE+ + D S Q L+ E+ ++ L H
Sbjct: 501 WQKGQLLRQGSFGSVYEAISED-GDFFAVKEVSLLDQGSQAQECIQQLEGEIALLSQLEH 559
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
NI++Y G + + IF+E SL L +I D +++ +YT Q+L+GL LH
Sbjct: 560 QNILRYRGTDKDGSNLYIFLELVTQGSLLELYRRYQIRDSLIS-LYTKQILDGLKYLHHK 618
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
G +HRDIK IL+D NG +K DFG AK+ +K K T +M
Sbjct: 619 GFIHRDIKCATILVDANGTVKLADFGLAKV--------------SKLNDIKSRKETLFWM 664
Query: 1438 APETVTGQGHGKFGSD-DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTK 1496
APE + + + + S DIWSLGC VLEM TG+ P+++L+ A ++ + G LP+ P
Sbjct: 665 APEVINRKDNDGYRSPADIWSLGCTVLEMCTGQIPYSDLEPVEA-LFRIRRGTLPEVP-- 721
Query: 1497 SEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+S R FI +CL + +R TA ELL P++
Sbjct: 722 DTLSLDARHFILKCLKLNPEERPTATELLNHPFV 755
>YLR362w [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 717
Score = 160 bits (406), Expect = 1e-38
Identities = 103/316 (32%), Positives = 163/316 (50%), Gaps = 62/316 (19%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEI---------------------------- 1290
W K + IGSGSFG+VY +N TG+++AVK++
Sbjct: 415 WLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQ 474
Query: 1291 --KIQDAKSM----------KQIFPSLKEEMRVMEILNHPNIVQYYGVEVHRDKVNIFME 1338
KI+D ++ +++ +L+ EM +++ L+H NIV YYG +NIF+E
Sbjct: 475 QEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLE 534
Query: 1339 FCEGSSLASLL-EHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDIKPENILLDRNGVI 1397
+ G S++S+L +G E+ ++T +T Q+L G+A LH+ ++HRDIK NIL+D G +
Sbjct: 535 YVPGGSVSSMLNNYGPFEESLITN-FTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCV 593
Query: 1398 KYVDFGAAKLIA---KNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTGQGHGKFGSDD 1454
K DFG +K ++ K +KR SL G+ +M+PE V + D
Sbjct: 594 KITDFGISKKLSPLNKKQNKRASLQ------------GSVFWMSPEVV--KQTATTAKAD 639
Query: 1455 IWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGRKFISRCLIQD 1514
IWS GCVV+EM TG+ P+ + AI + + P+ P S +S G+ F+ + D
Sbjct: 640 IWSTGCVVIEMFTGKHPFPDFSQMQAI-FKIGTNTTPEIP--SWATSEGKNFLRKAFELD 696
Query: 1515 ANKRATAMELLLDPWI 1530
R +A+ELL PW+
Sbjct: 697 YQYRPSALELLQHPWL 712
>Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 291
Score = 157 bits (396), Expect = 2e-37
Identities = 93/276 (33%), Positives = 145/276 (51%), Gaps = 16/276 (5%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKI--QDAKSMKQIFPSLKEEMRVMEILN 1316
W K IG G+F + Y A ++ TG ++AVK++ + +++ +L+EE+R+M LN
Sbjct: 20 WLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLN 79
Query: 1317 HPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQ 1376
HPNI++ G + N+F+E+ G S+A LL E V YT QLL GL+ LH+
Sbjct: 80 HPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHE 139
Query: 1377 SGVVHRDIKPENILLDRNGV-IKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
+ ++HRD+K N+L+D G ++ DFGAA +A G+ ++GT
Sbjct: 140 NQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQG--------QLLGTIA 191
Query: 1436 YMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW--ANLDNEWAIMYHVAAGHLPQF 1493
+MAPE + GQ +G+ S D+WS+GC ++EM + PW N A+++ V
Sbjct: 192 FMAPEVLRGQQYGR--SCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKVIIASATTA 249
Query: 1494 PT-KSEISSAGRKFISRCLIQDANKRATAMELLLDP 1528
P+ S +S R RCL R + ELL P
Sbjct: 250 PSIPSHLSPGLRDVALRCLELQPQDRPPSRELLKHP 285
>At5g66850 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 376
Score = 155 bits (391), Expect = 6e-37
Identities = 98/277 (35%), Positives = 149/277 (53%), Gaps = 27/277 (9%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKI--QDAKSMKQIFPSLKEEMRVMEIL 1315
+W+K IG G+FG+VY A N +TG + A+KE+++ D KS + I L++E++++ L
Sbjct: 4 QWKKGKLIGRGTFGSVYVASNSETGALCAMKEVELFPDDPKSAECI-KQLEQEIKLLSNL 62
Query: 1316 NHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLL-EHGRIEDEMVTQVYTLQLLEGLACL 1374
HPNIVQY+G E D+ I++E+ S+ + +H E V + +T +L GLA L
Sbjct: 63 QHPNIVQYFGSETVEDRFFIYLEYVHPGSINKYIRDHCGTMTESVVRNFTRHILSGLAYL 122
Query: 1375 HQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
H VHRDIK N+L+D +GV+K DFG AK + +R L + G+P
Sbjct: 123 HNKKTVHRDIKGANLLVDASGVVKLADFGMAKHLT---GQRADL----------SLKGSP 169
Query: 1435 MYMAPETVTGQGHGKFGSD------DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAG 1488
+MAPE + K + DIWSLGC ++EM TG+ PW+ + A M+ V
Sbjct: 170 YWMAPEVLMQAVMQKDSNPDLAFAVDIWSLGCTIIEMFTGKPPWSEFEGA-AAMFKVMR- 227
Query: 1489 HLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELL 1525
P +S G+ F+ C ++ +R TA LL
Sbjct: 228 --DSPPIPESMSPEGKDFLRLCFQRNPAERPTASMLL 262
>At3g13530 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1368
Score = 155 bits (391), Expect = 6e-37
Identities = 89/272 (32%), Positives = 151/272 (54%), Gaps = 21/272 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G++G VY ++L+ GD +A+K++ +++ +++ ++ +E+ +++ LNH NIV+Y
Sbjct: 26 IGKGAYGRVYKGLDLENGDFVAIKQVSLENI--VQEDLNTIMQEIDLLKNLNHKNIVKYL 83
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIED--EMVTQVYTLQLLEGLACLHQSGVVHR 1382
G + ++I +E+ E SLA++++ + E + VY Q+LEGL LH+ GV+HR
Sbjct: 84 GSSKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVAVYIAQVLEGLVYLHEQGVIHR 143
Query: 1383 DIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
DIK NIL + G++K DFG A +K D N S ++GTP +MAPE +
Sbjct: 144 DIKGANILTTKEGLVKLADFGVA-------TKLNEADVNTHS-----VVGTPYWMAPEVI 191
Query: 1443 TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSA 1502
+ G + DIWS+GC V+E++T P+ +L ++ + P P +S
Sbjct: 192 --EMSGVCAASDIWSVGCTVIELLTCVPPYYDL-QPMPALFRIVQDDNPPIP--DSLSPD 246
Query: 1503 GRKFISRCLIQDANKRATAMELLLDPWISQIR 1534
F+ +C +D+ +R A LL PWI R
Sbjct: 247 ITDFLRQCFKKDSRQRPDAKTLLSHPWIRNSR 278
>7298926 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 704
Score = 154 bits (390), Expect = 8e-37
Identities = 92/280 (32%), Positives = 153/280 (53%), Gaps = 20/280 (7%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
++ K IG G+ GTVY+A+ TG +A+K++ + + I E+ VM H
Sbjct: 429 KYTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQQPKKELII----NEILVMRENKH 484
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
PN+V Y + +++ + ME+ G SL ++ +++ + V ++L+ L LH +
Sbjct: 485 PNVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTETCMDEGQIAAVCR-EVLQALEFLHAN 543
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
V+HRDIK +NILL +G +K DFG I+ SKR + M+GTP +M
Sbjct: 544 QVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKRTT------------MVGTPYWM 591
Query: 1438 APETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKS 1497
APE VT + +G D+WSLG + +EMV G P+ N +N +Y +A P+ K
Sbjct: 592 APEVVTRKQYGP--KVDLWSLGIMAIEMVEGEPPYLN-ENPLKALYLIATNGKPEIKEKD 648
Query: 1498 EISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNIA 1537
++SSA + F+ +CL + ++RA+A++LL P++ R +A
Sbjct: 649 KLSSAFQDFLDQCLEVEVDRRASALDLLKHPFLKLARPLA 688
>HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 618
Score = 154 bits (389), Expect = 1e-36
Identities = 98/270 (36%), Positives = 149/270 (54%), Gaps = 17/270 (6%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQ-DAKSMKQIFPSLKEEMRVMEILNH 1317
W+ +G G+FG VY ++DTG LAVK+++ D+ + +L+ E+++++ H
Sbjct: 355 WRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNFLH 414
Query: 1318 PNIVQYYGV--EVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLH 1375
IVQYYG + ++IFME+ G S+ L+ E T+ YT Q+LEG+ LH
Sbjct: 415 ERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENGTRKYTRQILEGVHYLH 474
Query: 1376 QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
+ ++HRDIK NIL D G +K DFGA+K + + I L TG K + GTP
Sbjct: 475 SNMILHRDIKGANILRDSTGNVKLGDFGASKRL-----QTICL----SGTGMKSVTGTPY 525
Query: 1436 YMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPT 1495
+M+PE ++GQG+G+ DIWS+ C V+EM+T + PWA + AI P+ P
Sbjct: 526 WMSPEVISGQGYGR--KADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLP- 582
Query: 1496 KSEISSAGRKFISRCLIQDANKRATAMELL 1525
+S R F+ R + +A R +A ELL
Sbjct: 583 -PHVSDYTRDFLKRIFV-EAKLRPSADELL 610
>Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 620
Score = 154 bits (389), Expect = 1e-36
Identities = 99/270 (36%), Positives = 150/270 (54%), Gaps = 17/270 (6%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQ-DAKSMKQIFPSLKEEMRVMEILNH 1317
W+ +G G+FG VY ++DTG LAVK+++ D+ + +L+ E+++++ L H
Sbjct: 357 WRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLH 416
Query: 1318 PNIVQYYGV--EVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLH 1375
IVQYYG + ++IFME+ G S+ L+ E VT+ YT Q+LEG+ LH
Sbjct: 417 ERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLH 476
Query: 1376 QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
+ +V RDIK NIL D G +K DFGA+K + + I L TG K + GTP
Sbjct: 477 SNMIVLRDIKGANILRDSTGNVKLGDFGASKRL-----QTICL----SGTGMKSVTGTPY 527
Query: 1436 YMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPT 1495
+M+PE ++G+G+G+ DIWS+ C V+EM+T + PWA + AI P+ P
Sbjct: 528 WMSPEVISGEGYGR--KADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLP- 584
Query: 1496 KSEISSAGRKFISRCLIQDANKRATAMELL 1525
+S R F+ R + +A R +A ELL
Sbjct: 585 -PHVSDYTRDFLKRIFV-EAKLRPSADELL 612
>CE27177 [T] KOG4279 Serine/threonine protein kinase
Length = 1378
Score = 154 bits (389), Expect = 1e-36
Identities = 114/325 (35%), Positives = 164/325 (50%), Gaps = 35/325 (10%)
Query: 1215 AITDMEKVVKVKRHYSVGKVIDDTDNQXXXXXXXXXXXXXXXXRWQKRSFIGSGSFGTVY 1274
A DM+ + V G+V+ + DN+ +R +G G++GTVY
Sbjct: 627 AYDDMKSMADVADGNYQGRVLSNPDNEKIRFEYELSNS-------NERVVLGKGTYGTVY 679
Query: 1275 SAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYYGVEV-----H 1329
+A ++DT + VKEI++ K +++ P L EE+ + L H NIVQY G ++
Sbjct: 680 AARDMDTQRQIVVKEIEV---KYDEEVQP-LMEEISLHSTLCHANIVQYLGCDLVGKDGS 735
Query: 1330 RDKVNIFMEFCEGSSLASLLEH--GRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDIKPE 1387
D IFME G SL+SLL G + +E Y Q+LEGL LH+ +VHRDIK +
Sbjct: 736 NDHFLIFMEHVPGGSLSSLLRSKWGPM-NENAMNYYGKQILEGLKYLHELKIVHRDIKGD 794
Query: 1388 NILLDR-NGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTGQG 1446
N+L++ +GV K DFG K +A G ++ + GT YMAPE +
Sbjct: 795 NVLVNTYSGVCKISDFGTCKRLA--GLNPVT----------ETFTGTLQYMAPEVIDHGQ 842
Query: 1447 HGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHL-PQFPTKSEISSAGRK 1505
G DIWS GC ++EM TGR P+ + N A M+ V P PT EI+ R
Sbjct: 843 RGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPT--EITEKCRN 900
Query: 1506 FISRCLIQDANKRATAMELLLDPWI 1530
FI C + +A R +A +LL DP+I
Sbjct: 901 FIKSCFLPEACDRPSAKDLLQDPFI 925
>At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 422
Score = 153 bits (387), Expect = 2e-36
Identities = 97/278 (34%), Positives = 151/278 (53%), Gaps = 30/278 (10%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMK-QIFPSLKEEMRVMEILNH 1317
WQK +G GS G+VY ++ D GD A KE+ + D S + ++ + ++ L H
Sbjct: 153 WQKGQLLGRGSLGSVYEGISAD-GDFFAFKEVSLLDQGSQAHEWIQQVEGGIALLSQLQH 211
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
NIV+Y G + IF+E SL L + ++ D +V+ +YT Q+L+GL LH
Sbjct: 212 QNIVRYRGTTKDESNLYIFLELVTQGSLRKLYQRNQLGDSVVS-LYTRQILDGLKYLHDK 270
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM-- 1435
G +HR+IK N+L+D NG +K DFG AK+++ + TP
Sbjct: 271 GFIHRNIKCANVLVDANGTVKLADFGLAKVMS--------------------LWRTPYWN 310
Query: 1436 YMAPETVTG-QGHGKFGSD-DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQF 1493
+MAPE + + + +G+ DIWSLGC VLEM+TG+ P+++L+ A +Y++ G LP+
Sbjct: 311 WMAPEVILNPKDYDGYGTPADIWSLGCTVLEMLTGQIPYSDLEIGTA-LYNIGTGKLPKI 369
Query: 1494 PTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWIS 1531
P +S R FI CL + +R TA ELL P+++
Sbjct: 370 P--DILSLDARDFILTCLKVNPEERPTAAELLNHPFVN 405
>Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 544
Score = 153 bits (386), Expect = 2e-36
Identities = 92/266 (34%), Positives = 143/266 (53%), Gaps = 20/266 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G+ GTVY+A+++ TG +A+K++ +Q + I E+ VM +PNIV Y
Sbjct: 274 IGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELII----NEILVMRENKNPNIVNYL 329
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ D++ + ME+ G SL ++ +++ + V + L+ L LH + V+HRDI
Sbjct: 330 DSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCR-ECLQALDFLHSNQVIHRDI 388
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K +NILL +G +K DFG I SKR M+GTP +MAPE VT
Sbjct: 389 KSDNILLGMDGSVKLTDFGFCAQITPEQSKR------------STMVGTPYWMAPEVVTR 436
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+ +G DIWSLG + +EMV G P+ N +N +Y +A P+ +S+ R
Sbjct: 437 KAYGP--KVDIWSLGIMAIEMVEGEPPYLN-ENPLRALYLIATNGTPELQNPERLSAVFR 493
Query: 1505 KFISRCLIQDANKRATAMELLLDPWI 1530
F++RCL D ++R +A ELL P++
Sbjct: 494 DFLNRCLEMDVDRRGSAKELLQHPFL 519
>Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 525
Score = 153 bits (386), Expect = 2e-36
Identities = 92/266 (34%), Positives = 138/266 (51%), Gaps = 19/266 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G+ GTV++A ++ G +A+K+I +Q + I E+ VM+ L +PNIV +
Sbjct: 255 IGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELII----NEILVMKELKNPNIVNFL 310
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ D++ + ME+ G SL ++ DE + L+ L LH + V+HRDI
Sbjct: 311 DSYLVGDELFVVMEYLAGGSLTDVVTETACMDEAQIAAVCRECLQALEFLHANQVIHRDI 370
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K +N+LL G +K DFG I SKR M+GTP +MAPE VT
Sbjct: 371 KSDNVLLGMEGSVKLTDFGFCAQITPEQSKR------------STMVGTPYWMAPEVVTR 418
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+ +G DIWSLG + +EMV G P+ N +N +Y +A P+ ++S R
Sbjct: 419 KAYGP--KVDIWSLGIMAIEMVEGEPPYLN-ENPLRALYLIATNGTPELQNPEKLSPIFR 475
Query: 1505 KFISRCLIQDANKRATAMELLLDPWI 1530
F++RCL D KR +A ELL P++
Sbjct: 476 DFLNRCLEMDVEKRGSAKELLQHPFL 501
>At3g07980 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1367
Score = 152 bits (383), Expect = 5e-36
Identities = 91/273 (33%), Positives = 151/273 (54%), Gaps = 23/273 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G++G VY ++L+ GD +A+K++ +++ ++ ++ +E+ +++ LNH NIV+Y
Sbjct: 26 IGKGAYGRVYIGLDLENGDFVAIKQVSLENIG--QEDLNTIMQEIDLLKNLNHKNIVKYL 83
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLE---HGRIEDEMVTQVYTLQLLEGLACLHQSGVVH 1381
G + ++I +E+ E SLA++++ G + +VT VY Q+LEGL LH+ GV+H
Sbjct: 84 GSLKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVT-VYIAQVLEGLVYLHEQGVIH 142
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
RDIK NIL + G++K DFG A +K D N S ++GTP +MAPE
Sbjct: 143 RDIKGANILTTKEGLVKLADFGVA-------TKLNEADFNTHS-----VVGTPYWMAPEV 190
Query: 1442 VTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISS 1501
+ + G + DIWS+GC ++E++T P+ +L +Y + P P +S
Sbjct: 191 I--ELSGVCAASDIWSVGCTIIELLTCVPPYYDL-QPMPALYRIVQDDTPPIP--DSLSP 245
Query: 1502 AGRKFISRCLIQDANKRATAMELLLDPWISQIR 1534
F+ C +D+ +R A LL PWI R
Sbjct: 246 DITDFLRLCFKKDSRQRPDAKTLLSHPWIRNSR 278
>Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 545
Score = 150 bits (380), Expect = 1e-35
Identities = 91/261 (34%), Positives = 140/261 (52%), Gaps = 20/261 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G+ GTVY+A+++ TG +A+K++ +Q + I E+ VM +PNIV Y
Sbjct: 276 IGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELII----NEILVMRENKNPNIVNYL 331
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ D++ + ME+ G SL ++ +++ + V + L+ L LH + V+HRDI
Sbjct: 332 DSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCR-ECLQALEFLHSNQVIHRDI 390
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K +NILL +G +K DFG I SKR M+GTP +MAPE VT
Sbjct: 391 KSDNILLGMDGSVKLTDFGFCAQITPEQSKR------------STMVGTPYWMAPEVVTR 438
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+ +G DIWSLG + +EM+ G P+ N +N +Y +A P+ ++S+ R
Sbjct: 439 KAYGP--KVDIWSLGIMAIEMIEGEPPYLN-ENPLRALYLIATNGTPELQNPEKLSAIFR 495
Query: 1505 KFISRCLIQDANKRATAMELL 1525
F++RCL D KR +A ELL
Sbjct: 496 DFLNRCLDMDVEKRGSAKELL 516
>At4g08470 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 560
Score = 149 bits (377), Expect = 3e-35
Identities = 101/274 (36%), Positives = 141/274 (50%), Gaps = 21/274 (7%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQ-IFPSLKEEMRVMEILNH 1317
W K +G GS+ +VY A++ D GD AVKE+ + D Q L+ E+ ++ L H
Sbjct: 303 WLKGQLLGRGSYASVYEAISED-GDFFAVKEVSLLDKGIQAQECIQQLEGEIALLSQLQH 361
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
NIV+Y G K+ IF+E S+ L E ++ +V+ +YT Q+L GL LH
Sbjct: 362 QNIVRYRGTAKDVSKLYIFLELVTQGSVQKLYERYQLSYTVVS-LYTRQILAGLNYLHDK 420
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
G VHRDIK N+L+D NG +K DFG A+ +K GT +M
Sbjct: 421 GFVHRDIKCANMLVDANGTVKLADFGLAEA--------------SKFNDIMSCKGTLFWM 466
Query: 1438 APETVTGQGHGKFGSD-DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTK 1496
APE + + GS DIWSLGC VLEM TG+ P+++L A + + G LP P
Sbjct: 467 APEVINRKDSDGNGSPADIWSLGCTVLEMCTGQIPYSDLKPIQA-AFKIGRGTLPDVP-- 523
Query: 1497 SEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+S R FI CL + +R TA ELL P++
Sbjct: 524 DTLSLDARHFILTCLKVNPEERPTAAELLHHPFV 557
>Hs5174547 [T] KOG4279 Serine/threonine protein kinase
Length = 1374
Score = 149 bits (376), Expect = 3e-35
Identities = 100/274 (36%), Positives = 149/274 (53%), Gaps = 23/274 (8%)
Query: 1262 RSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIV 1321
R +G G++G VY+ +L +A+KEI +D++ + L EE+ + + L H NIV
Sbjct: 683 RVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQP----LHEEIALHKHLKHKNIV 738
Query: 1322 QYYGVEVHRDKVNIFMEFCEGSSLASLLEH--GRIED-EMVTQVYTLQLLEGLACLHQSG 1378
QY G + IFME G SL++LL G ++D E YT Q+LEGL LH +
Sbjct: 739 QYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQ 798
Query: 1379 VVHRDIKPENILLDR-NGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
+VHRDIK +N+L++ +GV+K DFG +K +A N T + GT YM
Sbjct: 799 IVHRDIKGDNVLINTYSGVLKISDFGTSKRLA----------GINPCT--ETFTGTLQYM 846
Query: 1438 APETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHL-PQFPTK 1496
APE + G + DIWSLGC ++EM TG+ P+ L A M+ V + P+ P
Sbjct: 847 APEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIP-- 904
Query: 1497 SEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+S+ + FI +C D +KRA A +LL+D ++
Sbjct: 905 ESMSAEAKAFILKCFEPDPDKRACANDLLVDEFL 938
>At1g07150 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 499
Score = 148 bits (374), Expect = 6e-35
Identities = 95/284 (33%), Positives = 153/284 (53%), Gaps = 29/284 (10%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILN-H 1317
W + + IG G FG V +A++ G++ AVK + + A S+ SL+ E+ V L H
Sbjct: 23 WVRGACIGRGCFGAVSTAISKTNGEVFAVKSVDL--ATSLPTQSESLENEISVFRSLKPH 80
Query: 1318 PNIVQYYGVEVHRDKV----NIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLAC 1373
P IV++ G V ++ N+++E+ +AS G+IEDE + Q YT L+ L
Sbjct: 81 PYIVKFLGDGVSKEGTTTFRNLYLEYLPNGDVASHRAGGKIEDETLLQRYTACLVSALRH 140
Query: 1374 LHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGT 1433
+H G VH D+K NIL+ ++ ++K DFG+A I + R + G+
Sbjct: 141 VHSQGFVHCDVKARNILVSQSSMVKLADFGSAFRI---HTPRALITPR----------GS 187
Query: 1434 PMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWAN--LDNEWAIMYHVAAGHLP 1491
P++MAPE + + G D+WSLGC ++EM TG+ W + +D+ I + + LP
Sbjct: 188 PLWMAPEVIRREYQGP--ESDVWSLGCTIIEMFTGKPAWEDHGIDSLSRISF---SDELP 242
Query: 1492 QFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRN 1535
FP+K +S GR F+ +CL +D N+R + +LL P++SQ N
Sbjct: 243 VFPSK--LSEIGRDFLEKCLKRDPNQRWSCDQLLQHPFLSQCHN 284
>At4g26890 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 444
Score = 148 bits (373), Expect = 8e-35
Identities = 91/279 (32%), Positives = 149/279 (52%), Gaps = 37/279 (13%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHP 1318
W + IG GS TV A++ +G++ AVK + + L++E ++ L+ P
Sbjct: 5 WTRGPIIGRGSTATVSIAIS-SSGELFAVKSADLSSSSL-------LQKEQSILSTLSSP 56
Query: 1319 NIVQYYGVEVHRDK----VNIFMEFCEGSSLASLLEH--GRIEDEMVTQVYTLQLLEGLA 1372
++V+Y G + R+ NI ME+ G +L L+++ G++ + + YT Q+L GL
Sbjct: 57 HMVKYIGTGLTRESNGLVYNILMEYVSGGNLHDLIKNSGGKLPEPEIRS-YTRQILNGLV 115
Query: 1373 CLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIG 1432
LH+ G+VH D+K N+L++ NGV+K D G AK + K+ + G
Sbjct: 116 YLHERGIVHCDLKSHNVLVEENGVLKIADMGCAKSVDKS-----------------EFSG 158
Query: 1433 TPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVA-AGHLP 1491
TP +MAPE G+ +F + D+W+LGC ++EM+TG PW L++ A MY + +G P
Sbjct: 159 TPAFMAPEVARGE-EQRFPA-DVWALGCTMIEMMTGSSPWPELNDVVAAMYKIGFSGESP 216
Query: 1492 QFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
P + IS + F+ CL +D +R T ELL P++
Sbjct: 217 AIP--AWISDKAKDFLKNCLKEDQKQRWTVEELLKHPFL 253
>YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 939
Score = 146 bits (369), Expect = 2e-34
Identities = 92/269 (34%), Positives = 142/269 (52%), Gaps = 20/269 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G+ G VY+A + T +A+K++ ++ + I E+ VM+ HPNIV +
Sbjct: 626 IGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELII----NEILVMKGSKHPNIVNFI 681
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
V + + + ME+ EG SL ++ H + + + V + L GL LH GV+HRDI
Sbjct: 682 DSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAVCR-ETLSGLEFLHSKGVLHRDI 740
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K +NILL G IK DFG I + KR + M+GTP +MAPE V+
Sbjct: 741 KSDNILLSMEGDIKLTDFGFCAQINELNLKRTT------------MVGTPYWMAPEVVSR 788
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+ +G DIWSLG +++EM+ G P+ N + +Y +A P+ +SS+ +
Sbjct: 789 KEYGP--KVDIWSLGIMIIEMIEGEPPYLN-ETPLRALYLIATNGTPKLKEPENLSSSLK 845
Query: 1505 KFISRCLIQDANKRATAMELLLDPWISQI 1533
KF+ CL + RA+A ELL D +I++I
Sbjct: 846 KFLDWCLCVEPEDRASATELLHDEYITEI 874
>Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 894
Score = 146 bits (369), Expect = 2e-34
Identities = 91/270 (33%), Positives = 142/270 (51%), Gaps = 18/270 (6%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IGSG++G VY A N++TG++ A+K IK++ + F +++E+ +M+ HPNIV Y+
Sbjct: 22 IGSGTYGDVYKARNVNTGELAAIKVIKLEPGED----FAVVQQEIIMMKDCKHPNIVAYF 77
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G + RDK+ I MEFC G SL + E+ + + L+GL LH G +HRDI
Sbjct: 78 GSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDI 137
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K NILL NG +K DFG + I +KR K IGTP +MAPE
Sbjct: 138 KGANILLTDNGHVKLADFGVSAQITATIAKR------------KSFIGTPYWMAPEVAAV 185
Query: 1445 QGHGKFGS-DDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAG-HLPQFPTKSEISSA 1502
+ G + D+W++G +E+ + P +L A+ + P+ K + S++
Sbjct: 186 ERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNS 245
Query: 1503 GRKFISRCLIQDANKRATAMELLLDPWISQ 1532
F+ L ++ KR TA +LL P+++Q
Sbjct: 246 FHHFVKMALTKNPKKRPTAEKLLQHPFVTQ 275
>CE27573 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1420
Score = 145 bits (367), Expect = 4e-34
Identities = 94/303 (31%), Positives = 146/303 (48%), Gaps = 24/303 (7%)
Query: 1231 VGKVIDDTDNQXXXXXXXXXXXXXXXXRWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEI 1290
+GKVI D + + +W I SGSFG+V+ A+++D+ ++A K +
Sbjct: 1097 IGKVITDDNRRNFVLATDKKITTKAPFQWALLDHIASGSFGSVHRAMDIDSHRVIAAKVM 1156
Query: 1291 KIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLE 1350
+IQ ++ +++ E+ + L H N+V+YYGV+V V IFME+C +L +
Sbjct: 1157 RIQ-----RENHKAIESEINIFRQLIHENLVKYYGVQVEDSDVIIFMEYCSQGTLERIC- 1210
Query: 1351 HGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAK 1410
HG+++ +MV Q YT LL + LH ++HRDIKP NI LD+ V+K DFG + + +
Sbjct: 1211 HGKMDLKMVRQ-YTNSLLRAVQYLHSHKIIHRDIKPANIFLDKCTVLKLGDFGCSSRLVE 1269
Query: 1411 NGSKRISLDANNKSTGGKDMIGTPMYMAPE--------TVTGQGHGKFGSDDIWSLGCVV 1462
+ + GTP +MAPE TG G S DIW+LG V
Sbjct: 1270 SSTVYGEFQTT---------AGTPQFMAPEIYSYGEKDETTGSYSGYGRSVDIWALGATV 1320
Query: 1463 LEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATAM 1522
+ M+TG+ P+ P +P ++ ++F C N R TA
Sbjct: 1321 VNMMTGKVPFEGQTRHQIAFALCFRKQKPTYPDIADKRPDVKRFFDNCFEFLPNDRPTAA 1380
Query: 1523 ELL 1525
ELL
Sbjct: 1381 ELL 1383
>CE07737 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1418
Score = 145 bits (367), Expect = 4e-34
Identities = 94/303 (31%), Positives = 146/303 (48%), Gaps = 24/303 (7%)
Query: 1231 VGKVIDDTDNQXXXXXXXXXXXXXXXXRWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEI 1290
+GKVI D + + +W I SGSFG+V+ A+++D+ ++A K +
Sbjct: 1097 IGKVITDDNRRNFVLATDKKITTKAPFQWALLDHIASGSFGSVHRAMDIDSHRVIAAKVM 1156
Query: 1291 KIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLE 1350
+IQ ++ +++ E+ + L H N+V+YYGV+V V IFME+C +L +
Sbjct: 1157 RIQ-----RENHKAIESEINIFRQLIHENLVKYYGVQVEDSDVIIFMEYCSQGTLERIC- 1210
Query: 1351 HGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAK 1410
HG+++ +MV Q YT LL + LH ++HRDIKP NI LD+ V+K DFG + + +
Sbjct: 1211 HGKMDLKMVRQ-YTNSLLRAVQYLHSHKIIHRDIKPANIFLDKCTVLKLGDFGCSSRLVE 1269
Query: 1411 NGSKRISLDANNKSTGGKDMIGTPMYMAPE--------TVTGQGHGKFGSDDIWSLGCVV 1462
+ + GTP +MAPE TG G S DIW+LG V
Sbjct: 1270 SSTVYGEFQTT---------AGTPQFMAPEIYSYGEKDETTGSYSGYGRSVDIWALGATV 1320
Query: 1463 LEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATAM 1522
+ M+TG+ P+ P +P ++ ++F C N R TA
Sbjct: 1321 VNMMTGKVPFEGQTRHQIAFALCFRKQKPTYPDIADKRPDVKRFFDNCFEFLPNDRPTAA 1380
Query: 1523 ELL 1525
ELL
Sbjct: 1381 ELL 1383
>Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 591
Score = 144 bits (363), Expect = 1e-33
Identities = 88/268 (32%), Positives = 147/268 (54%), Gaps = 20/268 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GS G V A +G ++AVK++ ++ + + +F E+ +M H N+V+ Y
Sbjct: 327 IGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLF----NEVVIMRDYQHENVVEMY 382
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ D++ + MEF EG +L ++ H R+ +E + V L +L+ L+ LH GV+HRDI
Sbjct: 383 NSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAV-CLAVLQALSVLHAQGVIHRDI 441
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K ++ILL +G +K DFG ++K +R K ++GTP +MAPE ++
Sbjct: 442 KSDSILLTHDGRVKLSDFGFCAQVSKEVPRR------------KSLVGTPYWMAPELISR 489
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+G DIWSLG +V+EMV G P+ N + M + P+ ++S + +
Sbjct: 490 LPYGP--EVDIWSLGIMVIEMVDGEPPYFN-EPPLKAMKMIRDNLPPRLKNLHKVSPSLK 546
Query: 1505 KFISRCLIQDANKRATAMELLLDPWISQ 1532
F+ R L++D +RATA ELL P++++
Sbjct: 547 GFLDRLLVRDPAQRATAAELLKHPFLAK 574
>Hs4758702 [T] KOG4279 Serine/threonine protein kinase
Length = 1011
Score = 144 bits (362), Expect = 1e-33
Identities = 97/274 (35%), Positives = 145/274 (52%), Gaps = 21/274 (7%)
Query: 1261 KRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNI 1320
+R +G G++G VY+ + T +A+KEI +D++ + L EE+ + L H NI
Sbjct: 373 ERLVLGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQP----LHEEIALHRRLRHKNI 428
Query: 1321 VQYYGVEVHRDKVNIFMEFCEGSSLASLLEH--GRIED-EMVTQVYTLQLLEGLACLHQS 1377
V+Y G + IFME G SL+SLL G ++D E YT Q+L+GL LH +
Sbjct: 429 VRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDN 488
Query: 1378 GVVHRDIKPENILLDR-NGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
+VHRDIK +N+L++ +G++K DFG +K +A + + GT Y
Sbjct: 489 HIVHRDIKGDNVLINTFSGLLKISDFGTSKRLA------------GITPCTETFTGTLQY 536
Query: 1437 MAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTK 1496
MAPE + G + DIWSLGC V+EM TGR P+ L + A M+ V + P
Sbjct: 537 MAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGM-YKVHPPMP 595
Query: 1497 SEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
S +S+ + F+ R D RA+A LL DP++
Sbjct: 596 SSLSAEAQAFLLRTFEPDPRLRASAQTLLGDPFL 629
>7300559 [T] KOG4279 Serine/threonine protein kinase
Length = 1310
Score = 144 bits (362), Expect = 1e-33
Identities = 97/275 (35%), Positives = 149/275 (53%), Gaps = 23/275 (8%)
Query: 1261 KRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNI 1320
++ +G G++GTVY+A + T +A+KE+ ++++ ++ L EE+++ L H NI
Sbjct: 581 RKMVLGKGTYGTVYAARDKQTQVRIAIKEVPEKNSQDVQP----LHEEIKLHSQLRHRNI 636
Query: 1321 VQYYGVEVHRDKVNIFMEFCEGSSLASLLEH--GRIEDEMVTQV-YTLQLLEGLACLHQS 1377
V+Y G IFME G SL+ LLE G ++D T Y+ Q+LEGL LH+
Sbjct: 637 VRYLGSCSENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQ 696
Query: 1378 GVVHRDIKPENILLDR-NGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
+VHRDIK +N+L++ +GV+K DFG +K +A+ N T + GT Y
Sbjct: 697 DIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLARI----------NPMT--ETFTGTLQY 744
Query: 1437 MAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPT- 1495
MAPE + G + DIWS GC +EM TG+ P+ L + A M+ V G + P
Sbjct: 745 MAPEVIDQGVRGYGPAADIWSFGCTNVEMATGKPPFIELGSAHAAMFKV--GFYKKHPNI 802
Query: 1496 KSEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
E+S+ + FI RC R +A +LL DP++
Sbjct: 803 PEELSANAKNFILRCFAISVMDRPSASQLLEDPFL 837
>Hs14771959 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 719
Score = 143 bits (361), Expect = 2e-33
Identities = 90/266 (33%), Positives = 143/266 (52%), Gaps = 20/266 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GS G V A TG +AVK++ ++ + + +F E+ +M +H N+V Y
Sbjct: 455 IGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLF----NEVVIMRDYHHDNVVDMY 510
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ D++ + MEF EG +L ++ H R+ +E + V L +L L+ LH GV+HRDI
Sbjct: 511 SSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIATV-CLSVLRALSYLHNQGVIHRDI 569
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K ++ILL +G IK DFG ++K KR K ++GTP +MAPE ++
Sbjct: 570 KSDSILLTSDGRIKLSDFGFCAQVSKEVPKR------------KSLVGTPYWMAPEVISR 617
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+G DIWSLG +V+EM+ G P+ N + M + P+ ++SS R
Sbjct: 618 LPYGT--EVDIWSLGIMVIEMIDGEPPYFN-EPPLQAMRRIRDSLPPRVKDLHKVSSVLR 674
Query: 1505 KFISRCLIQDANKRATAMELLLDPWI 1530
F+ L+++ ++RATA ELL P++
Sbjct: 675 GFLDLMLVREPSQRATAQELLGHPFL 700
>At2g32510 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 372
Score = 143 bits (361), Expect = 2e-33
Identities = 86/284 (30%), Positives = 148/284 (51%), Gaps = 37/284 (13%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHP 1318
W + +G GS TVY+A ++ +ILAVK ++ ++ L+ E +++ L+ P
Sbjct: 3 WTRGRILGRGSTATVYAAAGHNSDEILAVKSSEVHRSEF-------LQREAKILSSLSSP 55
Query: 1319 NIVQYYGVEVHRDK-----VNIFMEFCEGSSL--ASLLEHGRIEDEMVTQVYTLQLLEGL 1371
++ Y G E R+ N+ ME+ +L A+ + GR+++ V + YT +L+GL
Sbjct: 56 YVIGYRGSETKRESNGVVMYNLLMEYAPYGTLTDAAAKDGGRVDETRVVK-YTRDILKGL 114
Query: 1372 ACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMI 1431
+H G+VH D+K N+++ G K DFG AK + ++
Sbjct: 115 EYIHSKGIVHCDVKGSNVVISEKGEAKIADFGCAKRV--------------DPVFESPVM 160
Query: 1432 GTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNE---WAIMYHVA-A 1487
GTP +MAPE G+ GK DIW++GC ++EMVTG PW D+ +++Y V +
Sbjct: 161 GTPAFMAPEVARGEKQGK--ESDIWAVGCTMIEMVTGSPPWTKADSREDPVSVLYRVGYS 218
Query: 1488 GHLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWIS 1531
P+ P ++ + F+ +CL ++AN+R TA +LL P+++
Sbjct: 219 SETPELPCL--LAEEAKDFLEKCLKREANERWTATQLLNHPFLT 260
>YAR019c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 974
Score = 143 bits (360), Expect = 2e-33
Identities = 92/282 (32%), Positives = 144/282 (50%), Gaps = 30/282 (10%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
++ + IG GS+G VY A+N T ++A+KE+ ++ + + I E+ +++ LNH
Sbjct: 24 QYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMA----EISLLKNLNH 79
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEH---GRIEDEMVTQVYTLQLLEGLACL 1374
NIV+Y+G ++ I +E+C SL L+ G E+E T Y Q L GL L
Sbjct: 80 NNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKT--YVTQTLLGLKYL 137
Query: 1375 HQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
H GV+HRDIK NILL + +K DFG + ++ ++ + GT
Sbjct: 138 HGEGVIHRDIKAANILLSADNTVKLADFGVSTIV---------------NSSALTLAGTL 182
Query: 1435 MYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFP 1494
+MAPE + +G DIWSLG V+EM+T P+ NL + A +Y+ P
Sbjct: 183 NWMAPEILGNRGASTL--SDIWSLGATVVEMLTKNPPYHNLTD--ANIYYAVENDTYYPP 238
Query: 1495 TKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNI 1536
S S + F+S+C +++ KR TA +LL WI+ N+
Sbjct: 239 --SSFSEPLKDFLSKCFVKNMYKRPTADQLLKHVWINSTENV 278
>7293601 [T] KOG0577 Serine/threonine protein kinase
Length = 1039
Score = 143 bits (360), Expect = 2e-33
Identities = 90/272 (33%), Positives = 144/272 (52%), Gaps = 20/272 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GSFG VY A T +I+A+K++ +S ++ + + +E+R + LNHPN ++Y
Sbjct: 33 IGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEK-WQDILKEIRFLRQLNHPNTIEYK 91
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G + + ME+C GS+ + H + E L +L GL+ LH G +HRDI
Sbjct: 92 GCYLRESTAWLVMEYCVGSASDIIEVHKKPLHEDEIAAICLGVLSGLSYLHSLGRIHRDI 151
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K NILL NGV+K DFG+A I AN+ +GTP +MAPE +
Sbjct: 152 KAGNILLTDNGVVKLADFGSA---------AIKCPANS-------FVGTPYWMAPEVILA 195
Query: 1445 QGHGKF-GSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAG 1503
G++ G D+WSLG +E+ + P+ N+ N + +YH+A P P K++ S A
Sbjct: 196 MDEGQYDGKVDVWSLGITCIELAERKPPYFNM-NAMSALYHIAQNESPTLP-KNDWSDAF 253
Query: 1504 RKFISRCLIQDANKRATAMELLLDPWISQIRN 1535
F+ CL + +R ++ +LL ++++ R+
Sbjct: 254 CSFVELCLKKMPAERPSSAKLLTHAYVTRPRS 285
>SPAC1006.09 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 699
Score = 142 bits (359), Expect = 3e-33
Identities = 105/422 (24%), Positives = 213/422 (49%), Gaps = 17/422 (4%)
Query: 355 LNKTGGSTDSLESFSNIETQLALEQLSNNHLVRERLEWQTMLSSVLNGDIVKSEKTKLAK 414
L+ + + ++S N+ + L+ + L N +ER EWQ ML+SVL GDIV+SEK +L K
Sbjct: 286 LDSETSTVNWVQSVLNLPSLLS-DDLMANPKNKERFEWQYMLTSVLTGDIVRSEKLRLRK 344
Query: 415 RKPDEILLN--HNDLIWLELKAWLNGRTVEDQRKSLEYSKTTADEVFEEILNYXXXXXXX 472
N ++D +W+E+ WL R+V+ R++L++ +T +V I+N+
Sbjct: 345 IASSREGRNSDYSDNLWMEIWCWLTHRSVDSYRENLKHLRTGMVDVLLAIMNFHWDESNE 404
Query: 473 XXXXXXXAKIL--LNKYYKVVGYWKNLPNMNLEKPVTKTSNFVSRIEALNSLINSYEGLQ 530
+L L+KY ++ + + ++ E + + +F +++ L + N L+
Sbjct: 405 LTPIVAVDNMLQKLDKYERL---YPSRRSILQEHSLYASESFQHKLDVLTAYSNVTHALE 461
Query: 531 YEIEALKQWTQNDDLDVTF-TKDSLDTEGIFKNDRSFAEQIMKEKDIEGIFQKKIFFKHA 589
++ ++ W N+++D+T T +S++ N F E+ +E + F+++I
Sbjct: 462 IQVNIIRSWVGNEEMDITKNTTNSINNVSQISNG-PFVERFYRETGLIRAFEQRIMTNMN 520
Query: 590 PWMFKSKLVFLKQQNSIHEMRLPLPVDKLHSLLTFPLRLIQEIISIRLEYARKLKKPTMM 649
+ K + + + LPL D LL+FP RLI+E +++RL A + ++
Sbjct: 521 SVLSKVCNTIVTYADDLKSYGLPLIADDYMRLLSFPFRLIKEFLNLRLSCAENITSISLF 580
Query: 650 MIDQMIDDFSTYIKLSVQI--KHTLM--EYRSGWSLKVEISDAFDAKVVEAIEFLFKLLH 705
ID ++DD +K++V I +HT++ +R S V+ + + + +V +++F F LLH
Sbjct: 581 TIDSLLDDLRNTMKVAVHIIQQHTVLIKPFRDD-SKFVDENQSLNNILVASLKFYFNLLH 639
Query: 706 LKLIDSSKNSFKTFKEPDILFAHWENLKNFGCYISGASKVIAQGFVNITIRLLNRLHLYI 765
K+ + + FKE +IL W+ L +I +++++ ++ +L ++ Y+
Sbjct: 640 RKVRNGC--ALLHFKETEILEGEWDFLLAVCPHIEHGFQIMSKSLSSLVGEILTNINRYL 697
Query: 766 ME 767
+
Sbjct: 698 KD 699
>CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 572
Score = 142 bits (357), Expect = 5e-33
Identities = 88/280 (31%), Positives = 147/280 (52%), Gaps = 20/280 (7%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
+++K IGSG+ G+VY+A+ + T +A+K++ ++D + I E+ VM H
Sbjct: 294 KYRKVDKIGSGASGSVYTAIEISTEAEVAIKQMNLKDQPKKELII----NEILVMRENKH 349
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
NIV Y + D++ + ME+ G SL ++ ++ED ++ V ++L+ L LH
Sbjct: 350 ANIVNYLDSYLVCDELWVVMEYLAGGSLTDVVTECQMEDGIIAAVCR-EVLQALEFLHSR 408
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
V+HRDIK +NILL +G +K DFG ++ KR + M+GTP +M
Sbjct: 409 HVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQRKRTT------------MVGTPYWM 456
Query: 1438 APETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKS 1497
APE VT + +G D+WSLG + +EMV G P+ N +N +Y +A P FP +
Sbjct: 457 APEVVTRKQYGP--KVDVWSLGIMAIEMVEGEPPYLN-ENPLRAIYLIATNGKPDFPGRD 513
Query: 1498 EISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNIA 1537
++ + F+ L R +A +LL P++ + +A
Sbjct: 514 SMTLLFKDFVDSALEVQVENRWSASQLLTHPFLRCAKPLA 553
>Hs19923464 [T] KOG0577 Serine/threonine protein kinase
Length = 898
Score = 141 bits (356), Expect = 7e-33
Identities = 86/271 (31%), Positives = 137/271 (49%), Gaps = 20/271 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GSFG VY A N T +++A+K++ K + + + +E++ + L HPN ++Y
Sbjct: 30 IGHGSFGAVYFATNAHTNEVVAIKKMSYS-GKQTHEKWQDILKEVKFLRQLKHPNTIEYK 88
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G + + ME+C GS+ L H + E+ T L GLA LH ++HRDI
Sbjct: 89 GCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALHGLAYLHSHALIHRDI 148
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K NILL G +K DFG+A + + S +GTP +MAPE +
Sbjct: 149 KAGNILLTEPGQVKLADFGSASMASPANS----------------FVGTPYWMAPEVILA 192
Query: 1445 QGHGKF-GSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAG 1503
G++ G DIWSLG +E+ + P N+ N + +YH+A P + +E + +
Sbjct: 193 MDEGQYDGKVDIWSLGITCIELAERKPPLFNM-NAMSALYHIAQNDSPTLQS-NEWTDSF 250
Query: 1504 RKFISRCLIQDANKRATAMELLLDPWISQIR 1534
R+F+ CL + +R T+ ELL ++ + R
Sbjct: 251 RRFVDYCLQKIPQERPTSAELLRHDFVRRDR 281
>At3g15220 [T] KOG0201 Serine/threonine protein kinase
Length = 690
Score = 141 bits (356), Expect = 7e-33
Identities = 91/277 (32%), Positives = 139/277 (49%), Gaps = 19/277 (6%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
R+ + IG GSFG VY A + D +A+K I +++++ + +++E+ V+
Sbjct: 14 RFSQIELIGRGSFGDVYKAFDKDLNKEVAIKVIDLEESEDEIE---DIQKEISVLSQCRC 70
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
P I +YYG +H+ K+ I ME+ G S+A LL+ DE T LL + LH
Sbjct: 71 PYITEYYGSYLHQTKLWIIMEYMAGGSVADLLQSNNPLDETSIACITRDLLHAVEYLHNE 130
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
G +HRDIK NILL NG +K DFG + + + S+R K +GTP +M
Sbjct: 131 GKIHRDIKAANILLSENGDVKVADFGVSAQLTRTISRR------------KTFVGTPFWM 178
Query: 1438 APETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKS 1497
APE + G DIWSLG V+EM G P A+L + +++ + PQ
Sbjct: 179 APEVIQ-NSEGYNEKADIWSLGITVIEMAKGEPPLADL-HPMRVLFIIPRETPPQL--DE 234
Query: 1498 EISSAGRKFISRCLIQDANKRATAMELLLDPWISQIR 1534
S ++F+S CL + +R +A EL+ +I R
Sbjct: 235 HFSRQVKEFVSLCLKKAPAERPSAKELIKHRFIKNAR 271
>At1g53165 [T] KOG0201 Serine/threonine protein kinase
Length = 1007
Score = 141 bits (356), Expect = 7e-33
Identities = 91/277 (32%), Positives = 140/277 (49%), Gaps = 19/277 (6%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
R+ + IG GSFG VY A + + +A+K I +++++ + +++E+ V+
Sbjct: 341 RFSQFELIGRGSFGDVYKAFDTELNKDVAIKVIDLEESEDEIE---DIQKEISVLSQCRC 397
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
P I +YYG +H+ K+ I ME+ G S+A LL+ G DE+ T LL + LH
Sbjct: 398 PYITEYYGSYLHQTKLWIIMEYMAGGSVADLLQPGNPLDEISIACITRDLLHAVEYLHAE 457
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
G +HRDIK NILL NG +K DFG + + + S+R K +GTP +M
Sbjct: 458 GKIHRDIKAANILLSENGDVKVADFGVSAQLTRTISRR------------KTFVGTPFWM 505
Query: 1438 APETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKS 1497
APE + G DIWSLG ++EM G P A+L + +++ + PQ
Sbjct: 506 APEVIQ-NSEGYNEKADIWSLGITMIEMAKGEPPLADL-HPMRVLFIIPRESPPQL--DE 561
Query: 1498 EISSAGRKFISRCLIQDANKRATAMELLLDPWISQIR 1534
S ++F+S CL + +R A ELL +I R
Sbjct: 562 HFSRPLKEFVSFCLKKAPAERPNAKELLKHRFIKNAR 598
>At1g05100 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 339
Score = 139 bits (351), Expect = 3e-32
Identities = 90/286 (31%), Positives = 146/286 (50%), Gaps = 39/286 (13%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHP 1318
W + +G GS TV +A ++G+ LAVK + ++ L+ E +++ LN P
Sbjct: 3 WTRGKTLGRGSTATVSAATCHESGETLAVKSAEFHRSEF-------LQREAKILSSLNSP 55
Query: 1319 NIVQYYGVEVHRDKVN---------IFMEFCEGSSLASLL-EHGRIEDEMVTQVYTLQLL 1368
++ Y G E+ R+ + + ME+ +L + ++G DE YT Q+L
Sbjct: 56 YVIGYRGCEITREPFHNNGEATTYSLLMEYAPYGTLTDVATKNGGFIDEARVVKYTRQIL 115
Query: 1369 EGLACLHQS-GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGG 1427
GL +H S G+ H DIK N+L+ NG K DFG AK + ++ +
Sbjct: 116 LGLEYIHNSKGIAHCDIKGSNVLVGENGEAKIADFGCAKWVEPEITEPVR---------- 165
Query: 1428 KDMIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW--ANLDNEWAIMYHV 1485
GTP +MAPE G+ GK DIW++GC V+EMVTG +PW A+ + +++Y V
Sbjct: 166 ----GTPAFMAPEAARGERQGK--ESDIWAVGCTVIEMVTGSQPWIGADFTDPVSVLYRV 219
Query: 1486 A-AGHLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
G LP+ P ++ + F+ +CL ++A +R TA +LL P++
Sbjct: 220 GYLGELPELP--CSLTEQAKDFLGKCLKKEATERWTASQLLNHPFL 263
>SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 658
Score = 139 bits (350), Expect = 4e-32
Identities = 89/268 (33%), Positives = 141/268 (52%), Gaps = 20/268 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G+ G VYSA + T +A+K++ I + I E+ VM+ +H NIV +
Sbjct: 392 IGQGASGDVYSARQVGTNLSVAIKKMNINQQPKKEFIV----NEILVMKSHHHKNIVNFI 447
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
++ ++ + ME+ G SL ++ + + + + + + LEGL LH++G+VHRDI
Sbjct: 448 DTFFYKSELWMVMEYMRGGSLTEVVTNNTLSEGQIAAICK-ETLEGLQHLHENGIVHRDI 506
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K +NILL G IK DFG I N +KR + M+GTP +MAPE VT
Sbjct: 507 KSDNILLSLQGDIKLTDFGFCAQIDSNMTKRTT------------MVGTPYWMAPEVVTR 554
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+ +G D+WSLG + +EMV G P+ N +N +Y +A P+ +SS
Sbjct: 555 KEYG--FKVDVWSLGIMAIEMVEGEPPYLN-ENPLRALYLIATIGTPKISRPELLSSVFH 611
Query: 1505 KFISRCLIQDANKRATAMELLLDPWISQ 1532
F+S+ L + +R ++ ELL P++ Q
Sbjct: 612 DFLSKSLTVNPKQRPSSGELLRHPFLKQ 639
>YBR274w [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 527
Score = 138 bits (348), Expect = 6e-32
Identities = 95/283 (33%), Positives = 147/283 (51%), Gaps = 19/283 (6%)
Query: 1265 IGSGSFGTVYSA-VNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVM-EILNHPNIVQ 1322
+G G+F V +A + +D ILAVK I + K M + +E+ + + HPN+++
Sbjct: 21 VGQGAFACVKNAHLQMDPSIILAVKFIHVPTCKKMGLSDKDITKEVVLQSKCSKHPNVLR 80
Query: 1323 YYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLH-QSGVVH 1381
V ++ + I +E +G L +E D V Q Y QL+ + LH + GV H
Sbjct: 81 LIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAH 140
Query: 1382 RDIKPENILLDRNGVIKYVDFG-AAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPE 1440
RDIKPENILLD+NG +K DFG A++ K+G+ R+S+D G+P YMAPE
Sbjct: 141 RDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQR----------GSPPYMAPE 190
Query: 1441 TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW--ANLDNEWAIMYHVAAGHLPQFPTKSE 1498
+ + DIWS+G ++ ++TG+ PW +L+NE + + G+L P S+
Sbjct: 191 VLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGPW-SK 249
Query: 1499 ISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNIAFGGN 1541
I + + L D NKR T L L PW+ +R +F G+
Sbjct: 250 IEFTHLNLLRKILQPDPNKRVTLKALKLHPWV--LRRASFSGD 290
>At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 836
Score = 138 bits (347), Expect = 8e-32
Identities = 86/272 (31%), Positives = 144/272 (52%), Gaps = 21/272 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GS+G+VY A +L T +I+AVK I + + + + + ++ E+ +++ NHPN+V+Y
Sbjct: 255 LGKGSYGSVYKARDLKTSEIVAVKVISLTEGE---EGYEEIRGEIEMLQQCNHPNVVRYL 311
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLE--HGRIEDEMVTQVYTLQLLEGLACLHQSGVVHR 1382
G D + I ME+C G S+A L+ +E+ + + + L+GLA LH VHR
Sbjct: 312 GSYQGEDYLWIVMEYCGGGSVADLMNVTEEALEEYQIAYICR-EALKGLAYLHSIYKVHR 370
Query: 1383 DIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
DIK NILL G +K DFG A + + SKR IGTP +MAPE +
Sbjct: 371 DIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKR------------NTFIGTPHWMAPEVI 418
Query: 1443 TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSA 1502
Q + G D+W+LG +EM G P +++ + +++ ++ P K + S
Sbjct: 419 --QENRYDGKVDVWALGVSAIEMAEGLPPRSSV-HPMRVLFMISIEPAPMLEDKEKWSLV 475
Query: 1503 GRKFISRCLIQDANKRATAMELLLDPWISQIR 1534
F+++CL ++ R TA E+L ++ + +
Sbjct: 476 FHDFVAKCLTKEPRLRPTAAEMLKHKFVERCK 507
>At5g55090 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 448
Score = 137 bits (345), Expect = 1e-31
Identities = 89/284 (31%), Positives = 143/284 (50%), Gaps = 35/284 (12%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHP 1318
W + IG GS TV + ++GD AVK + + L+ E ++ L+ P
Sbjct: 6 WIRGPIIGRGSTATVSLGIT-NSGDFFAVKSAEFSSSAF-------LQREQSILSKLSSP 57
Query: 1319 NIVQYYGVEVHRDK----VNIFMEFCEGSSLASLLEH--GRIEDEMVTQVYTLQLLEGLA 1372
IV+Y G V ++ N+ ME+ G SL L+++ G++ + ++ YT Q+L+GL
Sbjct: 58 YIVKYIGSNVTKENDKLMYNLLMEYVSGGSLHDLIKNSGGKLPEPLIRS-YTRQILKGLM 116
Query: 1373 CLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIG 1432
LH G+VH D+K +N+++ + K VD G AK + +N + S G
Sbjct: 117 YLHDQGIVHCDVKSQNVMIGGE-IAKIVDLGCAKTVEENENLEFS--------------G 161
Query: 1433 TPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVA-AGHLP 1491
TP +M+PE G+ D+W+LGC V+EM TG PW L++ A +Y + G P
Sbjct: 162 TPAFMSPEVARGEEQSF--PADVWALGCTVIEMATGSSPWPELNDVVAAIYKIGFTGESP 219
Query: 1492 QFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRN 1535
P +S G+ F+ +CL +D +R T ELL P++ + N
Sbjct: 220 VIPV--WLSEKGQDFLRKCLRKDPKQRWTVEELLQHPFLDEEDN 261
>Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 487
Score = 137 bits (344), Expect = 2e-31
Identities = 86/276 (31%), Positives = 145/276 (52%), Gaps = 26/276 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GS+G+VY A++ +TG I+A+K++ ++ +++I +E+ +M+ + P++V+YY
Sbjct: 36 LGEGSYGSVYKAIHKETGQIVAIKQVPVES--DLQEII----KEISIMQQCDSPHVVKYY 89
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGR---IEDEMVTQVYTLQLLEGLACLHQSGVVH 1381
G + I ME+C S++ ++ EDE+ T + + L+GL LH +H
Sbjct: 90 GSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQST--LKGLEYLHFMRKIH 147
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
RDIK NILL+ G K DFG A + +KR +IGTP +MAPE
Sbjct: 148 RDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------------NTVIGTPFWMAPEV 195
Query: 1442 VTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISS 1501
+ G+ DIWSLG +EM G+ P+A++ AI + + P F S
Sbjct: 196 IQEIGYNCVA--DIWSLGITAIEMAEGKPPYADIHPMRAI-FMIPTNPPPTFRKPELWSD 252
Query: 1502 AGRKFISRCLIQDANKRATAMELLLDPWISQIRNIA 1537
F+ +CL++ +RATA +LL P++ + ++
Sbjct: 253 NFTDFVKQCLVKSPEQRATATQLLQHPFVRSAKGVS 288
>CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 540
Score = 136 bits (342), Expect = 3e-31
Identities = 82/271 (30%), Positives = 144/271 (52%), Gaps = 20/271 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GS G V +A + T I+AVK + ++ + + +F E+ ++ HPNIV+++
Sbjct: 255 IGEGSTGVVEAAYKISTKQIVAVKRMNLRKQQRRELLF----NEVSILRQYQHPNIVRFF 310
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ D++ + MEF EG SL ++ R+ + + + + Q+L L LH V+HRDI
Sbjct: 311 SSHLVDDELWVVMEFMEGGSLTDIVTATRMTEPQIATI-SRQVLGALDFLHARKVIHRDI 369
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K ++ILL R+G +K DFG +++ +R SL +GTP + A E +
Sbjct: 370 KSDSILLKRDGTVKLTDFGFCGQLSEEVPRRRSL------------VGTPYWTAAEVIAR 417
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+ + DIWS G +++EMV G P+ N D + M + H +F +++S
Sbjct: 418 EPYDT--RADIWSFGIMLIEMVEGEPPFFN-DQPFQAMKRIRDEHEARFSRHAKVSVELS 474
Query: 1505 KFISRCLIQDANKRATAMELLLDPWISQIRN 1535
+ +S C+++D NKR A +LL P+ ++ ++
Sbjct: 475 ELLSHCIVKDVNKRWPAKDLLRHPFFAKAQH 505
>CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 542
Score = 136 bits (342), Expect = 3e-31
Identities = 82/271 (30%), Positives = 144/271 (52%), Gaps = 20/271 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GS G V +A + T I+AVK + ++ + + +F E+ ++ HPNIV+++
Sbjct: 257 IGEGSTGVVEAAYKISTKQIVAVKRMNLRKQQRRELLF----NEVSILRQYQHPNIVRFF 312
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ D++ + MEF EG SL ++ R+ + + + + Q+L L LH V+HRDI
Sbjct: 313 SSHLVDDELWVVMEFMEGGSLTDIVTATRMTEPQIATI-SRQVLGALDFLHARKVIHRDI 371
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K ++ILL R+G +K DFG +++ +R SL +GTP + A E +
Sbjct: 372 KSDSILLKRDGTVKLTDFGFCGQLSEEVPRRRSL------------VGTPYWTAAEVIAR 419
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+ + DIWS G +++EMV G P+ N D + M + H +F +++S
Sbjct: 420 EPYDT--RADIWSFGIMLIEMVEGEPPFFN-DQPFQAMKRIRDEHEARFSRHAKVSVELS 476
Query: 1505 KFISRCLIQDANKRATAMELLLDPWISQIRN 1535
+ +S C+++D NKR A +LL P+ ++ ++
Sbjct: 477 ELLSHCIVKDVNKRWPAKDLLRHPFFAKAQH 507
>Hs7706401 [T] KOG0577 Serine/threonine protein kinase
Length = 1235
Score = 135 bits (340), Expect = 5e-31
Identities = 83/262 (31%), Positives = 133/262 (50%), Gaps = 20/262 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GSFG VY A ++ +++A+K++ +S ++ + + +E+R ++ L HPN +QY
Sbjct: 34 IGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEK-WQDIIKEVRFLQKLRHPNTIQYR 92
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G + + ME+C GS+ L H + E+ T L+GLA LH ++HRD+
Sbjct: 93 GCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAVTHGALQGLAYLHSHNMIHRDV 152
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K NILL G++K DFG+A ++A S +GTP +MAPE +
Sbjct: 153 KAGNILLSEPGLVKLGDFGSASIMAPANS----------------FVGTPYWMAPEVILA 196
Query: 1445 QGHGKF-GSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAG 1503
G++ G D+WSLG +E+ + P N+ N + +YH+A P + S
Sbjct: 197 MDEGQYDGKVDVWSLGITCIELAERKPPLFNM-NAMSALYHIAQNESPVLQS-GHWSEYF 254
Query: 1504 RKFISRCLIQDANKRATAMELL 1525
R F+ CL + R T+ LL
Sbjct: 255 RNFVDSCLQKIPQDRPTSEVLL 276
>Hs4759208 [T] KOG0577 Serine/threonine protein kinase
Length = 1049
Score = 135 bits (340), Expect = 5e-31
Identities = 83/262 (31%), Positives = 133/262 (50%), Gaps = 20/262 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GSFG VY A ++ +++A+K++ +S ++ + + +E+R ++ L HPN +QY
Sbjct: 34 IGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEK-WQDIIKEVRFLQKLRHPNTIQYR 92
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G + + ME+C GS+ L H + E+ T L+GLA LH ++HRD+
Sbjct: 93 GCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAVTHGALQGLAYLHSHNMIHRDV 152
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K NILL G++K DFG+A ++A S +GTP +MAPE +
Sbjct: 153 KAGNILLSEPGLVKLGDFGSASIMAPANS----------------FVGTPYWMAPEVILA 196
Query: 1445 QGHGKF-GSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAG 1503
G++ G D+WSLG +E+ + P N+ N + +YH+A P + S
Sbjct: 197 MDEGQYDGKVDVWSLGITCIELAERKPPLFNM-NAMSALYHIAQNESPVLQS-GHWSEYF 254
Query: 1504 RKFISRCLIQDANKRATAMELL 1525
R F+ CL + R T+ LL
Sbjct: 255 RNFVDSCLQKIPQDRPTSEVLL 276
>7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 1218
Score = 135 bits (340), Expect = 5e-31
Identities = 89/268 (33%), Positives = 132/268 (49%), Gaps = 18/268 (6%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IGSG++G VY A + + ++ A+K IK++ + ++ I ++E+ +M HPNI+ YY
Sbjct: 32 IGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQII----QQEIIMMRDCRHPNIIAYY 87
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G + RDK+ I MEFC G SL + + E+ + L+GL LH G +HRDI
Sbjct: 88 GSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDI 147
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K NILL G +K DFG + I +KR K IGTP +MAPE
Sbjct: 148 KGANILLTEYGDVKLADFGVSAQITATINKR------------KSFIGTPYWMAPEVAAV 195
Query: 1445 QGHGKFGS-DDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHL-PQFPTKSEISSA 1502
+ G + DIW+ G +E+ + P +L A+ +G P K + S
Sbjct: 196 ERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPT 255
Query: 1503 GRKFISRCLIQDANKRATAMELLLDPWI 1530
FI L ++ KR TA LL P++
Sbjct: 256 FHNFIKTALTKNPKKRPTAERLLQHPFV 283
>Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 681
Score = 134 bits (338), Expect = 9e-31
Identities = 88/268 (32%), Positives = 142/268 (52%), Gaps = 20/268 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GS G V A +G +AVK + ++ + + +F E+ +M H N+V+ Y
Sbjct: 413 IGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLF----NEVVIMRDYQHFNVVEMY 468
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ +++ + MEF +G +L ++ R+ +E + V +L+ LA LH GV+HRDI
Sbjct: 469 KSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEA-VLQALAYLHAQGVIHRDI 527
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K ++ILL +G +K DFG I+K+ KR K ++GTP +MAPE ++
Sbjct: 528 KSDSILLTLDGRVKLSDFGFCAQISKDVPKR------------KSLVGTPYWMAPEVISR 575
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+ DIWSLG +V+EMV G P+ + D+ M + P+ ++S R
Sbjct: 576 SLYAT--EVDIWSLGIMVIEMVDGEPPYFS-DSPVQAMKRLRDSPPPKLKNSHKVSPVLR 632
Query: 1505 KFISRCLIQDANKRATAMELLLDPWISQ 1532
F+ R L++D +RATA ELL P++ Q
Sbjct: 633 DFLERMLVRDPQERATAQELLDHPFLLQ 660
>Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 846
Score = 134 bits (338), Expect = 9e-31
Identities = 89/270 (32%), Positives = 138/270 (50%), Gaps = 18/270 (6%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+GSG++G VY A N+ TG++ AVK IK++ F +++E+ +++ H NIV Y+
Sbjct: 26 VGSGTYGDVYKARNVHTGELAAVKIIKLEPGDD----FSLIQQEIFMVKECKHCNIVAYF 81
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G + R+K+ I ME+C G SL + E+ + L+GLA LH G +HRDI
Sbjct: 82 GSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYVCRETLQGLAYLHTKGKMHRDI 141
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K NILL +G +K DFG A I +KR K IGTP +MAPE
Sbjct: 142 KGANILLTDHGDVKLADFGVAAKITATIAKR------------KSFIGTPYWMAPEVAAV 189
Query: 1445 QGHGKFGS-DDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAG-HLPQFPTKSEISSA 1502
+ +G + DIW++G +E+ + P +L A+ + P+ K++ SS
Sbjct: 190 EKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKLKDKTKWSST 249
Query: 1503 GRKFISRCLIQDANKRATAMELLLDPWISQ 1532
F+ L ++ KR TA LL +++Q
Sbjct: 250 FHNFVKIALTKNPKKRPTAERLLTHTFVAQ 279
>SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase
Length = 471
Score = 134 bits (337), Expect = 1e-30
Identities = 90/267 (33%), Positives = 139/267 (51%), Gaps = 22/267 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+GSGSFG V+ A +GDI+A+K+I D ++ +++E+ ++ N N++QYY
Sbjct: 15 LGSGSFGVVWKARENVSGDIIAIKQI---DLETGIDDITDIEQEVFMLSNCNSSNVIQYY 71
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G V + I ME +G S++ LL+ GR+ +E V + ++L GL LH +HRDI
Sbjct: 72 GCFVDGYTLWILMEHMDGGSVSGLLKMGRL-NEQVISIILREVLYGLNYLHGQNKIHRDI 130
Query: 1385 KPENILLDRN-GVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVT 1443
K NILL + G +K DFG A ++ S+R +GTP +MAPE +
Sbjct: 131 KAANILLSSSTGNVKLADFGVAAQLSNAASRR------------HTFVGTPFWMAPEVIQ 178
Query: 1444 GQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAG 1503
+G + DIWSLG +EM G P A + + +++ + P+ S
Sbjct: 179 QTSYGL--AADIWSLGITAIEMANGIPPRATM-HPMRVIFEIPQSEPPKL--DDHFSPTF 233
Query: 1504 RKFISRCLIQDANKRATAMELLLDPWI 1530
R F+S CL + N R +A ELL P+I
Sbjct: 234 RDFVSCCLDLNPNMRWSAKELLQHPFI 260
>Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 134 bits (336), Expect = 1e-30
Identities = 85/276 (30%), Positives = 146/276 (52%), Gaps = 26/276 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GS+G+V+ A++ ++G ++A+K++ ++ +++I +E+ +M+ + P +V+YY
Sbjct: 33 LGEGSYGSVFKAIHKESGQVVAIKQVPVES--DLQEII----KEISIMQQCDSPYVVKYY 86
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGR---IEDEMVTQVYTLQLLEGLACLHQSGVVH 1381
G + I ME+C S++ ++ IEDE+ T + + L+GL LH +H
Sbjct: 87 GSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKST--LKGLEYLHFMRKIH 144
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
RDIK NILL+ G K DFG A + +KR +IGTP +MAPE
Sbjct: 145 RDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------------NTVIGTPFWMAPEV 192
Query: 1442 VTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISS 1501
+ G+ DIWSLG +EM G+ P+A++ AI + + P F S
Sbjct: 193 IQEIGYNCVA--DIWSLGITSIEMAEGKPPYADIHPMRAI-FMIPTNPPPTFRKPELWSD 249
Query: 1502 AGRKFISRCLIQDANKRATAMELLLDPWISQIRNIA 1537
F+ +CL+++ +RATA +LL P+I + ++
Sbjct: 250 DFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVS 285
>Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 134 bits (336), Expect = 1e-30
Identities = 85/276 (30%), Positives = 146/276 (52%), Gaps = 26/276 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GS+G+V+ A++ ++G ++A+K++ ++ +++I +E+ +M+ + P +V+YY
Sbjct: 33 LGEGSYGSVFKAIHKESGQVVAIKQVPVES--DLQEII----KEISIMQQCDSPYVVKYY 86
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGR---IEDEMVTQVYTLQLLEGLACLHQSGVVH 1381
G + I ME+C S++ ++ IEDE+ T + + L+GL LH +H
Sbjct: 87 GSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKST--LKGLEYLHFMRKIH 144
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
RDIK NILL+ G K DFG A + +KR +IGTP +MAPE
Sbjct: 145 RDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------------NTVIGTPFWMAPEV 192
Query: 1442 VTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISS 1501
+ G+ DIWSLG +EM G+ P+A++ AI + + P F S
Sbjct: 193 IQEIGYNCVA--DIWSLGITSIEMAEGKPPYADIHPMRAI-FMIPTNPPPTFRKPELWSD 249
Query: 1502 AGRKFISRCLIQDANKRATAMELLLDPWISQIRNIA 1537
F+ +CL+++ +RATA +LL P+I + ++
Sbjct: 250 DFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVS 285
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 133 bits (335), Expect = 2e-30
Identities = 81/269 (30%), Positives = 132/269 (48%), Gaps = 16/269 (5%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G+G+F VY + TGD +A+K IK + + ++ E+ VM +L HPN+V+
Sbjct: 21 LGTGNFAKVYHGTEISTGDDVAIKVIKKDHVFKRRGMMEQIEREIAVMRLLRHPNVVELR 80
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
V + K+ ME+ G L +++ E + + Y QL+ + H GV HRDI
Sbjct: 81 EVMATKKKIFFVMEYVNGGELFEMIDRDGKLPEDLARKYFQQLISAVDFCHSRGVFHRDI 140
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMI----GTPMYMAPE 1440
KPEN+LLD G +K DFG + L+ G + D++ GTP Y+APE
Sbjct: 141 KPENLLLDGEGDLKVTDFGLSALMMPEG-------LGGRRGSSDDLLHTRCGTPAYVAPE 193
Query: 1441 TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEIS 1500
+ +G+ DIWS G V+ ++ G P+ +D +Y +FP +
Sbjct: 194 VLRNKGYDG-AMADIWSCGIVLYALLAGFLPF--IDENVMTLYTKIFKAECEFPPWFSLE 250
Query: 1501 SAGRKFISRCLIQDANKRATAMELLLDPW 1529
S ++ +SR L+ D +R + E+ + PW
Sbjct: 251 S--KELLSRLLVPDPEQRISMSEIKMIPW 277
>At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 348
Score = 133 bits (334), Expect = 3e-30
Identities = 88/271 (32%), Positives = 145/271 (53%), Gaps = 26/271 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IGSG+ GTVY ++ T A+K I ++++ + E+ ++ ++HPN+V+ +
Sbjct: 76 IGSGAGGTVYKVIHTPTSRPFALKVIYGNHEDTVRR---QICREIEILRSVDHPNVVKCH 132
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ H ++ + +EF + SL E I E + Q+L GLA LH+ +VHRDI
Sbjct: 133 DMFDHNGEIQVLLEFMDQGSL----EGAHIWQEQELADLSRQILSGLAYLHRRHIVHRDI 188
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV-T 1443
KP N+L++ +K DFG ++++A+ ++D N S +GT YM+PE + T
Sbjct: 189 KPSNLLINSAKNVKIADFGVSRILAQ------TMDPCNSS------VGTIAYMSPERINT 236
Query: 1444 GQGHGKFG--SDDIWSLGCVVLEMVTGRRPWA-NLDNEWA-IMYHVAAGHLPQFPTKSEI 1499
HG++ + D+WSLG +LE GR P+A + +WA +M + P+ P +
Sbjct: 237 DLNHGRYDGYAGDVWSLGVSILEFYLGRFPFAVSRQGDWASLMCAICMSQPPEAPATA-- 294
Query: 1500 SSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
S R F+S CL D KR +A +LL P+I
Sbjct: 295 SQEFRHFVSCCLQSDPPKRWSAQQLLQHPFI 325
>YHR102w [T] KOG0201 Serine/threonine protein kinase
Length = 1080
Score = 132 bits (331), Expect = 6e-30
Identities = 92/279 (32%), Positives = 138/279 (48%), Gaps = 32/279 (11%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEI-------KIQDAKSMKQIFPSLKEEMRV 1311
+++ IG G FG VY N+ TG + A+K + +++D + Q SLK+
Sbjct: 23 FKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQIS-- 80
Query: 1312 MEILNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGL 1371
NI +YYG + + I ME C G SL SLL G+I DE V +LL L
Sbjct: 81 -------NITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKI-DEKYIGVIMRELLVAL 132
Query: 1372 ACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMI 1431
C+H+ V+HRDIK N+L+ G +K DFG A + N S + M
Sbjct: 133 KCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQV------------NQTSLRRQTMA 180
Query: 1432 GTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLP 1491
GTP +MAPE + +G DIWSLG E+ TG P+ +++ A M + P
Sbjct: 181 GTPYWMAPEVIM-EGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRA-MQLIIKSKPP 238
Query: 1492 QFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+ +S S++ ++FI+ CL +D +R +A +LL +I
Sbjct: 239 RLEDRS-YSTSLKEFIALCLDEDPKERLSADDLLKSKFI 276
>7300224 [T] KOG0201 Serine/threonine protein kinase
Length = 642
Score = 132 bits (331), Expect = 6e-30
Identities = 84/278 (30%), Positives = 138/278 (49%), Gaps = 21/278 (7%)
Query: 1261 KRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNI 1320
K+ IG GSFG V+ ++ T ++A+K I +++A+ +++E+ V+ + P +
Sbjct: 15 KQERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDE---IDDIQQEIMVLSQCDSPYV 71
Query: 1321 VQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVV 1380
+YYG + K+ I ME+ G S L++ G E EM + ++L+GL LH +
Sbjct: 72 TKYYGSFLKGTKLWIIMEYLGGGSALDLMKAGSFE-EMHIGIILREVLKGLDYLHSERKL 130
Query: 1381 HRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPE 1440
HRDIK N+LL G +K DFG A + SKR +GTP +MAPE
Sbjct: 131 HRDIKAANVLLSEQGDVKLADFGVAGQLTNTTSKR------------NTFVGTPFWMAPE 178
Query: 1441 TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEIS 1500
+ + DIWSLG +E+ G P + L + +++ + + PQ +
Sbjct: 179 VIKQSQYD--AKADIWSLGITAIELAKGEPPNSEL-HPMRVLFLIPKNNPPQL--TGSYT 233
Query: 1501 SAGRKFISRCLIQDANKRATAMELLLDPWISQIRNIAF 1538
+ + F+ CL +D R TA ELL P+I + + A+
Sbjct: 234 KSFKDFVEACLNKDPENRPTAKELLKYPFIKKAKKNAY 271
>SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase
Length = 312
Score = 131 bits (330), Expect = 7e-30
Identities = 87/264 (32%), Positives = 134/264 (49%), Gaps = 19/264 (7%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
+++ IG GSFG+V+ A ++++ I+A +K+ D + K +L +E+ + LN
Sbjct: 5 QYRDLQLIGQGSFGSVFRAQDVESSKIVA---LKVVDLDATKDQIETLTQEINFLIDLNS 61
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
+I +YY V ++ I ME+C+G S LL+ E V Q+LE L LH
Sbjct: 62 VHITKYYASFVDGFRLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEALVYLHGQ 121
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
G +HRDIK NIL ++G++K DFG +G D N+ D +GTP +M
Sbjct: 122 GKMHRDIKAANILTMKDGLVKLADFGV------SGQLESLRDKND------DFVGTPFWM 169
Query: 1438 APETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKS 1497
APE V G+ DIWSLG E+ TG P++ + ++ + H P +S
Sbjct: 170 APEVVKQTGYNY--KADIWSLGITAYELATGEPPYSGIHPMKVLL--LIPKHSPPSLERS 225
Query: 1498 EISSAGRKFISRCLIQDANKRATA 1521
+ S A F+S CL ++ RATA
Sbjct: 226 KFSRAFCDFVSNCLKKNPKDRATA 249
>At5g67080 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 344
Score = 131 bits (329), Expect = 1e-29
Identities = 98/286 (34%), Positives = 146/286 (50%), Gaps = 31/286 (10%)
Query: 1259 WQKRSFIGSGSFGTVYSAV--NLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILN 1316
W + IG G+F TV A N D+G+ + +K D+ SL E V++ L
Sbjct: 3 WIRGETIGYGTFSTVSLATRSNNDSGEFPPLMAVKSADSYGAA----SLANEKSVLDNLG 58
Query: 1317 HP--NIVQYYG----VEVHRDKVNIFMEFCEGSSLASLLEH--GRIEDEMVTQVYTLQLL 1368
IV+ +G VE + N+F+E+ SL S L+ G E + +T +L
Sbjct: 59 DDCNEIVRCFGEDRTVENGEEMHNLFLEYASRGSLESYLKKLAGEGVPESTVRRHTGSVL 118
Query: 1369 EGLACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGK 1428
GL +H +G H D+K NILL +G +K DFG AK I L A N G
Sbjct: 119 RGLRHIHANGFAHCDLKLGNILLFGDGAVKIADFGLAKRIG-------DLTALNY---GV 168
Query: 1429 DMIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLD--NEWAIMYHVA 1486
+ GTP+YMAPE+V +G G D+W+LGCVV+EM +G+ W+ + N +++ +
Sbjct: 169 QIRGTPLYMAPESVNDNEYGSEG--DVWALGCVVVEMFSGKTAWSLKEGSNFMSLLLRIG 226
Query: 1487 AG-HLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWIS 1531
G +P P E+S GR F+S+C ++D KR TA LL P+++
Sbjct: 227 VGDEVPMIP--EELSEQGRDFLSKCFVKDPKKRWTAEMLLNHPFVT 270
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 131 bits (329), Expect = 1e-29
Identities = 82/277 (29%), Positives = 139/277 (49%), Gaps = 21/277 (7%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
R++ +G G+F VY A N+ TG +A+K + + + + +K E+ VM ++ H
Sbjct: 23 RYELGRLLGHGTFAKVYHARNIQTGKSVAMKVVGKEKVVKVGMV-DQIKREISVMRMVKH 81
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
PNIV+ + V + K+ ME G L + + GR+ ++ V +VY QL+ + H
Sbjct: 82 PNIVELHEVMASKSKIYFAMELVRGGELFAKVAKGRLRED-VARVYFQQLISAVDFCHSR 140
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
GV HRD+KPEN+LLD G +K DFG + ++ + D +T GTP Y+
Sbjct: 141 GVYHRDLKPENLLLDEEGNLKVTDFGLSAF-----TEHLKQDGLLHTT-----CGTPAYV 190
Query: 1438 APETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWA--NLDNEWAIMYHVAAGHLPQFPT 1495
APE + +G+ D+WS G ++ ++ G P+ NL N + +Y F
Sbjct: 191 APEVILKKGYDG-AKADLWSCGVILFVLLAGYLPFQDDNLVNMYRKIYR------GDFKC 243
Query: 1496 KSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
+SS R+ +++ L + N R T +++ PW +
Sbjct: 244 PGWLSSDARRLVTKLLDPNPNTRITIEKVMDSPWFKK 280
>7300149 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 569
Score = 131 bits (329), Expect = 1e-29
Identities = 84/281 (29%), Positives = 147/281 (51%), Gaps = 23/281 (8%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
R++ +G G+ G V+ A +L +AVK I +++ S I E+RV++ NH
Sbjct: 292 RYKTTQEVGKGASGIVFIAADLQNESQVAVKTIDMKNQSSKDLILT----EIRVLKDFNH 347
Query: 1318 PNIVQYYGVEV--HRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLH 1375
N+V + + D++ + ME+ +G L ++ +++ + V + L ++ LH
Sbjct: 348 KNLVNFLDAYLLEPEDQLWVVMEYMDGGPLTDVVTETVMKERQIACVCR-ETLYAISFLH 406
Query: 1376 QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
G++HRDIK +N+LL +G +K DFG I + KR + M+GTP
Sbjct: 407 AKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANI-EGDEKR------------QTMVGTPY 453
Query: 1436 YMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPT 1495
+MAPE VT + +GK DIWS+G + +EM+ G+ P+ + +Y +AA P +
Sbjct: 454 WMAPEVVTRKKYGK--KVDIWSIGIMAIEMIEGQPPYL-YETPLRALYLIAANGRPDIKS 510
Query: 1496 KSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNI 1536
++S + F+ RCL + ++RATA ELL P+++ +
Sbjct: 511 WDKLSPNLQDFLDRCLQVEVDRRATADELLSHPFLNDCSEV 551
>CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 378
Score = 130 bits (328), Expect = 1e-29
Identities = 86/283 (30%), Positives = 146/283 (51%), Gaps = 26/283 (9%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEI--KIQDAKSMKQIFPSLKEEMRVMEIL 1315
+++ + IG G+ GTV+ A + D++AVK + K Q K M L E++VM+
Sbjct: 107 KYEMKKQIGVGASGTVFVANVAGSTDVVAVKRMAFKTQPKKEM------LLTEIKVMKQY 160
Query: 1316 NHPNIVQYY-GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACL 1374
HPN+V Y V D + + M++ EG +L ++ +++ + V + L+ L L
Sbjct: 161 RHPNLVNYIESYLVDADDLWVVMDYLEGGNLTDVVVKTELDEGQIAAVLQ-ECLKALHFL 219
Query: 1375 HQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
H+ +VHRDIK +N+LL NG +K D G I + GSKR ++GTP
Sbjct: 220 HRHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQI-QPGSKR------------DTVVGTP 266
Query: 1435 MYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFP 1494
+M+PE + + + DIWSLG + LEM+ G P+ + +Y +A P+
Sbjct: 267 YWMSPEILNKKQYNY--KVDIWSLGIMALEMIDGEPPYLR-ETPLKAIYLIAQNGKPEIK 323
Query: 1495 TKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNIA 1537
+ +SS F+ +CL+ D ++RA ELL P++ + + ++
Sbjct: 324 QRDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPFLKKAKPLS 366
>CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 829
Score = 130 bits (327), Expect = 2e-29
Identities = 81/263 (30%), Positives = 129/263 (48%), Gaps = 18/263 (6%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+GSG++G VY A ++ + + AVK +K++ + F +++E+ V+ +HPNI+ Y+
Sbjct: 21 VGSGTYGEVYKARDIRSDSLAAVKVVKLEAGDN----FAVIQQEIMVIRECSHPNIIAYF 76
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G + RD++ I ME+C G SL + E+ + L GL LH G +HRDI
Sbjct: 77 GSYIRRDRLWIVMEYCGGGSLQDIYHLTGPLSELQIAFVCRETLRGLNYLHNMGKIHRDI 136
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K NILL +G +K DFG A I KR K IGTP +MAPE
Sbjct: 137 KGANILLSSSGDVKLADFGVAAQITATIGKR------------KSFIGTPYWMAPEVACV 184
Query: 1445 QGHGKFGSD-DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHL-PQFPTKSEISSA 1502
+ G +G D+W+ G +E+ + P +L + +G+ P K +
Sbjct: 185 EKRGGYGMQCDVWATGITAIELGECQPPLFDLHPMQVLYLMTKSGYKPPHLKDKHRWTPL 244
Query: 1503 GRKFISRCLIQDANKRATAMELL 1525
F+ +CL ++ KR + +LL
Sbjct: 245 FHDFVRQCLTKNPKKRPSPEKLL 267
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 130 bits (326), Expect = 2e-29
Identities = 90/266 (33%), Positives = 135/266 (49%), Gaps = 20/266 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G+F V A N DTGD +A+K I + ++ +K E+ +M+I+ HPNIV+ Y
Sbjct: 17 IGEGTFAKVKFARNTDTGDNVAIK-IMAKSTILKNRMVDQIKREISIMKIVRHPNIVRLY 75
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEH-GRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
V K+ I +EF G L + H GR+E E ++ Y QL++ +A H GV HRD
Sbjct: 76 EVLASPSKIYIVLEFVTGGELFDRIVHKGRLE-ESESRKYFQQLVDAVAHCHCKGVYHRD 134
Query: 1384 IKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVT 1443
+KPEN+LLD NG +K DFG + L + G + + + GTP Y+APE ++
Sbjct: 135 LKPENLLLDTNGNLKVSDFGLSAL-PQEGVELL-----------RTTCGTPNYVAPEVLS 182
Query: 1444 GQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAG 1503
GQG+ + DIWS G ++ ++ G P++ D AA +F S+
Sbjct: 183 GQGYDG-SAADIWSCGVILFVILAGYLPFSETDLPGLYRKINAA----EFSCPPWFSAEV 237
Query: 1504 RKFISRCLIQDANKRATAMELLLDPW 1529
+ I R L + R + DPW
Sbjct: 238 KFLIHRILDPNPKTRIQIQGIKKDPW 263
>SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 589
Score = 129 bits (325), Expect = 3e-29
Identities = 90/295 (30%), Positives = 151/295 (50%), Gaps = 32/295 (10%)
Query: 1265 IGSGSFGTVYSAV-----NLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPN 1319
+G G+ G+VY A L D +A+K I +Q ++ K++ + E+ VM HPN
Sbjct: 315 LGQGASGSVYLAKVVGGKQLGIFDSVAIKSIDLQ-CQTRKEL---ILNEITVMRESIHPN 370
Query: 1320 IVQYYGVEVHRDK-VNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSG 1378
IV Y + R++ + + ME+ SL ++E ++ + + ++ L+ +G+ LH
Sbjct: 371 IVTYLDSFLVRERHLWVVMEYMNAGSLTDIIEKSKLTEAQIARI-CLETCKGIQHLHARN 429
Query: 1379 VVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMA 1438
++HRDIK +N+LLD +G IK DFG ++ +KR++ M+GTP +MA
Sbjct: 430 IIHRDIKSDNVLLDNSGNIKITDFGFCARLSNRTNKRVT------------MVGTPYWMA 477
Query: 1439 PETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSE 1498
PE V +G DIWSLG +++EM+ P+ D A +Y +A P +
Sbjct: 478 PEVVKQNEYGT--KVDIWSLGIMIIEMIENEPPYLREDPIRA-LYLIAKNGTPTLKKPNL 534
Query: 1499 ISSAGRKFISRCLIQDANKRATAMELLLDPWISQ------IRNIAFGGNAESFNN 1547
+S + F++ CL D RATA ELL +++Q +++I F A + N
Sbjct: 535 VSKNLKSFLNSCLTIDTIFRATAAELLTHSFLNQACPTEDLKSIIFSRKANTHIN 589
>At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 366
Score = 129 bits (325), Expect = 3e-29
Identities = 87/271 (32%), Positives = 145/271 (53%), Gaps = 26/271 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IGSG+ GTVY ++ + + A+K I +++++ + E+ ++ +NHPN+V+ +
Sbjct: 85 IGSGAGGTVYKVIHRPSSRLYALKVIYGNHEETVRR---QICREIEILRDVNHPNVVKCH 141
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ ++ + +EF + SL E + E + Q+L GLA LH +VHRDI
Sbjct: 142 EMFDQNGEIQVLLEFMDKGSL----EGAHVWKEQQLADLSRQILSGLAYLHSRHIVHRDI 197
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV-T 1443
KP N+L++ +K DFG ++++A+ ++D N S +GT YM+PE + T
Sbjct: 198 KPSNLLINSAKNVKIADFGVSRILAQ------TMDPCNSS------VGTIAYMSPERINT 245
Query: 1444 GQGHGKFG--SDDIWSLGCVVLEMVTGRRPW-ANLDNEWA-IMYHVAAGHLPQFPTKSEI 1499
GK+ + DIWSLG +LE GR P+ + +WA +M + P+ P +
Sbjct: 246 DLNQGKYDGYAGDIWSLGVSILEFYLGRFPFPVSRQGDWASLMCAICMSQPPEAPATA-- 303
Query: 1500 SSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
S R FIS CL ++ KR +AM+LL P+I
Sbjct: 304 SPEFRHFISCCLQREPGKRRSAMQLLQHPFI 334
>7302458 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 596
Score = 129 bits (324), Expect = 4e-29
Identities = 87/274 (31%), Positives = 141/274 (50%), Gaps = 26/274 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GS+G+VY AV+ ++ I+A+K + ++ + +I +E+ +M+ + P +V+YY
Sbjct: 48 LGEGSYGSVYKAVHKESSSIVAIKLVPVES--DLHEII----KEISIMQQCDSPYVVRYY 101
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGR---IEDEMVTQVYTLQLLEGLACLHQSGVVH 1381
G + + I ME+C S++ ++ + EDE+ T + L+GL LH +H
Sbjct: 102 GSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILS--DTLQGLVYLHLRRKIH 159
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
RDIK NILL+ G K DFG A + +KR +IGTP +MAPE
Sbjct: 160 RDIKAANILLNTEGYAKLADFGVAGQLTDTMAKR------------NTVIGTPFWMAPEV 207
Query: 1442 VTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISS 1501
+ G+ DIWSLG LEM G+ P+ + AI + + P F S+
Sbjct: 208 IEEIGYDCVA--DIWSLGITALEMAEGKPPYGEIHPMRAI-FMIPQKPPPSFREPDRWST 264
Query: 1502 AGRKFISRCLIQDANKRATAMELLLDPWISQIRN 1535
F+S+CL+++ + RATA ELL +I ++
Sbjct: 265 EFIDFVSKCLVKEPDDRATATELLEHEFIRNAKH 298
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 129 bits (323), Expect = 5e-29
Identities = 81/274 (29%), Positives = 141/274 (50%), Gaps = 21/274 (7%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
+++ +G G+FG VY + TG+ +A+K I +D + + +K E+ +M ++ H
Sbjct: 14 KYEMGRLLGKGTFGKVYYGKEITTGESVAIKIIN-KDQVKREGMMEQIKREISIMRLVRH 72
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
PNIV+ V + K+ ME+ +G L S + G+++++ + Y QL+ + H
Sbjct: 73 PNIVELKEVMATKTKIFFIMEYVKGGELFSKIVKGKLKEDSARK-YFQQLISAVDFCHSR 131
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
GV HRD+KPEN+L+D NG +K DFG + L ++I D + GTP Y+
Sbjct: 132 GVSHRDLKPENLLVDENGDLKVSDFGLSAL-----PEQILQDGLLHT-----QCGTPAYV 181
Query: 1438 APETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW--ANLDNEWAIMYHVAAGHLPQFPT 1495
APE + +G+ DIWS G ++ ++ G P+ NL + ++ + P F
Sbjct: 182 APEVLRKKGYDG-AKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIFKSEFEYPPWFSP 240
Query: 1496 KSEISSAGRKFISRCLIQDANKRATAMELLLDPW 1529
+S ++ IS+ L+ D NKR + ++ PW
Sbjct: 241 ES------KRLISKLLVVDPNKRISIPAIMRTPW 268
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related proteins
Length = 460
Score = 128 bits (322), Expect = 6e-29
Identities = 95/273 (34%), Positives = 136/273 (49%), Gaps = 21/273 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEI---KIQDAKSMKQIFPSLKEEMRVMEILNHPNIV 1321
+GSG+F V AV +++G A+K I KI S K+ + E+ +++ L+HP +V
Sbjct: 173 LGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSLHHPGVV 232
Query: 1322 QYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVH 1381
Q + + + D++ I ME+ EG L L DE + QLLE L LH+ GV H
Sbjct: 233 QCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHLHKQGVTH 292
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
RDIKPENIL+ + +K DFG AK+I G T + GT Y+APE
Sbjct: 293 RDIKPENILITNDFHLKISDFGLAKVIHGTG------------TFLETFCGTMGYLAPEV 340
Query: 1442 VTGQG----HGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFP-TK 1496
+ + G DIWSLGCV+ M+T P+A+ I ++ G P P +
Sbjct: 341 LKSKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIEL-ISKGAYPIEPLLE 399
Query: 1497 SEISSAGRKFISRCLIQDANKRATAMELLLDPW 1529
+EIS G I+R L + KR + E L PW
Sbjct: 400 NEISEEGIDLINRMLEINPEKRISESEALQHPW 432
>At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 363
Score = 128 bits (321), Expect = 8e-29
Identities = 83/275 (30%), Positives = 142/275 (51%), Gaps = 25/275 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GS G V + TG A+K I++ +++++ ++ +E+++ + PN+V Y
Sbjct: 76 IGKGSSGVVQLVQHKWTGQFFALKVIQLNIDEAIRK---AIAQELKINQSSQCPNLVTSY 132
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGR-IEDEMVTQVYTLQLLEGLACLHQSG-VVHR 1382
+++ +E+ +G SLA L+ + I D ++ ++ Q+L+GL LH ++HR
Sbjct: 133 QSFYDNGAISLILEYMDGGSLADFLKSVKAIPDSYLSAIFR-QVLQGLIYLHHDRHIIHR 191
Query: 1383 DIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
D+KP N+L++ G +K DFG +S N + +GT YM+PE +
Sbjct: 192 DLKPSNLLINHRGEVKITDFG------------VSTVMTNTAGLANTFVGTYNYMSPERI 239
Query: 1443 TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWA--NLDNEWAIMYHVAAGHLPQFP---TKS 1497
G +G DIWSLG VVLE TG+ P+A N + W ++ + + Q P
Sbjct: 240 VGNKYG--NKSDIWSLGLVVLECATGKFPYAPPNQEETWTSVFELMEAIVDQPPPALPSG 297
Query: 1498 EISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
S FIS CL +D N R++A EL+ P++++
Sbjct: 298 NFSPELSSFISTCLQKDPNSRSSAKELMEHPFLNK 332
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 128 bits (321), Expect = 8e-29
Identities = 83/273 (30%), Positives = 146/273 (53%), Gaps = 17/273 (6%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
+++ +G G+F V+ A + TG +AVK + + + + ++K E+ +M L+H
Sbjct: 20 KYELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSH 79
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLL-EHGRIEDEMVTQVYTLQLLEGLACLHQ 1376
PNIV+ + V + K+ MEF +G L + + +HGR+ +++ ++ Y QL+ + H
Sbjct: 80 PNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDL-SRRYFQQLISAVGYCHA 138
Query: 1377 SGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
GV HRD+KPEN+L+D NG +K DFG + L + +I D + + GTP Y
Sbjct: 139 RGVYHRDLKPENLLIDENGNLKVSDFGLSAL-----TDQIRPDGLLHT-----LCGTPAY 188
Query: 1437 MAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTK 1496
+APE ++ +G+ + D+WS G V+ +V G P+ N+ +M + ++
Sbjct: 189 VAPEILSKKGY-EGAKVDVWSCGIVLFVLVAGYLPF----NDPNVMNMYKKIYKGEYRFP 243
Query: 1497 SEISSAGRKFISRCLIQDANKRATAMELLLDPW 1529
+S ++F+SR L + R T E+L DPW
Sbjct: 244 RWMSPDLKRFVSRLLDINPETRITIDEILKDPW 276
>Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 968
Score = 127 bits (320), Expect = 1e-28
Identities = 91/279 (32%), Positives = 134/279 (47%), Gaps = 21/279 (7%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHP 1318
W+ +G G+FG VY A N +TG + A K I+ + + ++ E+ ++ +HP
Sbjct: 36 WEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIV----EIEILATCDHP 91
Query: 1319 NIVQYYGVEVHRDKVNIFMEFCEGSSL-ASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
IV+ G H K+ I +EFC G ++ A +LE R E QV Q+LE L LH
Sbjct: 92 YIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSK 151
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
++HRD+K N+L+ G I+ DFG + K KR S IGTP +M
Sbjct: 152 RIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDS------------FIGTPYWM 199
Query: 1438 APETVTGQGHGKFGSD---DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFP 1494
APE V + D DIWSLG ++EM P L N ++ +A P
Sbjct: 200 APEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHEL-NPMRVLLKIAKSDPPTLL 258
Query: 1495 TKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQI 1533
T S+ S R F+ L ++ R +A +LL P++S I
Sbjct: 259 TPSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSSI 297
>CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 525
Score = 127 bits (320), Expect = 1e-28
Identities = 82/262 (31%), Positives = 136/262 (51%), Gaps = 24/262 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GS+G+V+ A++ ++G +LA+K++ + +++I +E+ +M+ +V+YY
Sbjct: 69 LGEGSYGSVHKAIHRESGHVLAIKKVPVDT--DLQEII----KEISIMQQCKSKYVVKYY 122
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGR--IEDEMVTQVYTLQLLEGLACLHQSGVVHR 1382
G + I ME+C S++ ++ R + ++ ++ V L+GL LH +HR
Sbjct: 123 GSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLR-DTLKGLQYLHDLKKIHR 181
Query: 1383 DIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
DIK NILL+ +G+ K DFG A + +KR +IGTP +MAPE +
Sbjct: 182 DIKAGNILLNTDGIAKLADFGVAGQLTDTMAKR------------NTVIGTPFWMAPEVI 229
Query: 1443 TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSA 1502
G+ DIWSLG +EM GR P++++ AI + + P F E SS
Sbjct: 230 EEIGYDT--KADIWSLGITAIEMAEGRPPYSDIHPMRAI-FMIPTKPPPTFKKPEEWSSE 286
Query: 1503 GRKFISRCLIQDANKRATAMEL 1524
FI CLI+ +R TA+ L
Sbjct: 287 FNDFIRSCLIKKPEERKTALRL 308
>CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 640
Score = 127 bits (320), Expect = 1e-28
Identities = 82/262 (31%), Positives = 136/262 (51%), Gaps = 24/262 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GS+G+V+ A++ ++G +LA+K++ + +++I +E+ +M+ +V+YY
Sbjct: 41 LGEGSYGSVHKAIHRESGHVLAIKKVPVDT--DLQEII----KEISIMQQCKSKYVVKYY 94
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGR--IEDEMVTQVYTLQLLEGLACLHQSGVVHR 1382
G + I ME+C S++ ++ R + ++ ++ V L+GL LH +HR
Sbjct: 95 GSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLR-DTLKGLQYLHDLKKIHR 153
Query: 1383 DIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
DIK NILL+ +G+ K DFG A + +KR +IGTP +MAPE +
Sbjct: 154 DIKAGNILLNTDGIAKLADFGVAGQLTDTMAKR------------NTVIGTPFWMAPEVI 201
Query: 1443 TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSA 1502
G+ DIWSLG +EM GR P++++ AI + + P F E SS
Sbjct: 202 EEIGYDT--KADIWSLGITAIEMAEGRPPYSDIHPMRAI-FMIPTKPPPTFKKPEEWSSE 258
Query: 1503 GRKFISRCLIQDANKRATAMEL 1524
FI CLI+ +R TA+ L
Sbjct: 259 FNDFIRSCLIKKPEERKTALRL 280
>CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 421
Score = 127 bits (320), Expect = 1e-28
Identities = 82/262 (31%), Positives = 136/262 (51%), Gaps = 24/262 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GS+G+V+ A++ ++G +LA+K++ + +++I +E+ +M+ +V+YY
Sbjct: 41 LGEGSYGSVHKAIHRESGHVLAIKKVPVDT--DLQEII----KEISIMQQCKSKYVVKYY 94
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGR--IEDEMVTQVYTLQLLEGLACLHQSGVVHR 1382
G + I ME+C S++ ++ R + ++ ++ V L+GL LH +HR
Sbjct: 95 GSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLR-DTLKGLQYLHDLKKIHR 153
Query: 1383 DIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
DIK NILL+ +G+ K DFG A + +KR +IGTP +MAPE +
Sbjct: 154 DIKAGNILLNTDGIAKLADFGVAGQLTDTMAKR------------NTVIGTPFWMAPEVI 201
Query: 1443 TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSA 1502
G+ DIWSLG +EM GR P++++ AI + + P F E SS
Sbjct: 202 EEIGYDT--KADIWSLGITAIEMAEGRPPYSDIHPMRAI-FMIPTKPPPTFKKPEEWSSE 258
Query: 1503 GRKFISRCLIQDANKRATAMEL 1524
FI CLI+ +R TA+ L
Sbjct: 259 FNDFIRSCLIKKPEERKTALRL 280
>CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 523
Score = 127 bits (320), Expect = 1e-28
Identities = 82/262 (31%), Positives = 136/262 (51%), Gaps = 24/262 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GS+G+V+ A++ ++G +LA+K++ + +++I +E+ +M+ +V+YY
Sbjct: 69 LGEGSYGSVHKAIHRESGHVLAIKKVPVDT--DLQEII----KEISIMQQCKSKYVVKYY 122
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGR--IEDEMVTQVYTLQLLEGLACLHQSGVVHR 1382
G + I ME+C S++ ++ R + ++ ++ V L+GL LH +HR
Sbjct: 123 GSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLR-DTLKGLQYLHDLKKIHR 181
Query: 1383 DIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
DIK NILL+ +G+ K DFG A + +KR +IGTP +MAPE +
Sbjct: 182 DIKAGNILLNTDGIAKLADFGVAGQLTDTMAKR------------NTVIGTPFWMAPEVI 229
Query: 1443 TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSA 1502
G+ DIWSLG +EM GR P++++ AI + + P F E SS
Sbjct: 230 EEIGYDT--KADIWSLGITAIEMAEGRPPYSDIHPMRAI-FMIPTKPPPTFKKPEEWSSE 286
Query: 1503 GRKFISRCLIQDANKRATAMEL 1524
FI CLI+ +R TA+ L
Sbjct: 287 FNDFIRSCLIKKPEERKTALRL 308
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 127 bits (319), Expect = 1e-28
Identities = 79/272 (29%), Positives = 137/272 (50%), Gaps = 17/272 (6%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
R++ F+G G+F VY A +L TGD +A+K I + + +K E+ M +L H
Sbjct: 11 RYEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMT-EQIKREISAMRLLRH 69
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
PNIV+ + V + K+ ME +G L + + G++ ++ V + Y QL+ + H
Sbjct: 70 PNIVELHEVMATKSKIYFVMEHVKGGELFNKVSTGKLRED-VARKYFQQLVRAVDFCHSR 128
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
GV HRD+KPEN+LLD +G +K DFG + L D+ + GTP Y+
Sbjct: 129 GVCHRDLKPENLLLDEHGNLKISDFGLSAL----------SDSRRQDGLLHTTCGTPAYV 178
Query: 1438 APETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKS 1497
APE ++ G+ F + D+WS G ++ ++ G P+ D+ +Y +FP +
Sbjct: 179 APEVISRNGYDGFKA-DVWSCGVILFVLLAGYLPFR--DSNLMELYKKIGKAEVKFP--N 233
Query: 1498 EISSAGRKFISRCLIQDANKRATAMELLLDPW 1529
++ ++ + R L + N R + +++ W
Sbjct: 234 WLAPGAKRLLKRILDPNPNTRVSTEKIMKSSW 265
>HsM5454174 [T] KOG0201 Serine/threonine protein kinase
Length = 426
Score = 126 bits (317), Expect = 2e-28
Identities = 80/268 (29%), Positives = 136/268 (49%), Gaps = 21/268 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GSFG VY ++ T +++A+K I +++A+ + +++E+ V+ + P I +Y+
Sbjct: 26 IGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIE---DIQQEITVLSQCDSPYITRYF 82
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G + K+ I ME+ G S LL+ G +E+ + + ++L+GL LH +HRDI
Sbjct: 83 GSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILR-EILKGLDYLHSERKIHRDI 141
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K N+LL G +K DFG A + KR +GTP +MAPE +
Sbjct: 142 KAANVLLSEQGDVKLADFGVAGQLTDTQIKR------------NTFVGTPFWMAPEVIKQ 189
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+ DIWSLG +E+ G P ++L + +++ + P + + S +
Sbjct: 190 SAYD--FKADIWSLGITAIELAKGEPPNSDL-HPMRVLFLIPKNSPPTL--EGQHSKPFK 244
Query: 1505 KFISRCLIQDANKRATAMELLLDPWISQ 1532
+F+ CL +D R TA ELL +I++
Sbjct: 245 EFVEACLNKDPRFRPTAKELLKHKFITR 272
>Hs21361358 [T] KOG0201 Serine/threonine protein kinase
Length = 426
Score = 126 bits (317), Expect = 2e-28
Identities = 80/268 (29%), Positives = 136/268 (49%), Gaps = 21/268 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GSFG VY ++ T +++A+K I +++A+ + +++E+ V+ + P I +Y+
Sbjct: 26 IGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIE---DIQQEITVLSQCDSPYITRYF 82
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G + K+ I ME+ G S LL+ G +E+ + + ++L+GL LH +HRDI
Sbjct: 83 GSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILR-EILKGLDYLHSERKIHRDI 141
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K N+LL G +K DFG A + KR +GTP +MAPE +
Sbjct: 142 KAANVLLSEQGDVKLADFGVAGQLTDTQIKR------------NTFVGTPFWMAPEVIKQ 189
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+ DIWSLG +E+ G P ++L + +++ + P + + S +
Sbjct: 190 SAYD--FKADIWSLGITAIELAKGEPPNSDL-HPMRVLFLIPKNSPPTL--EGQHSKPFK 244
Query: 1505 KFISRCLIQDANKRATAMELLLDPWISQ 1532
+F+ CL +D R TA ELL +I++
Sbjct: 245 EFVEACLNKDPRFRPTAKELLKHKFITR 272
>At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1168
Score = 126 bits (317), Expect = 2e-28
Identities = 81/276 (29%), Positives = 144/276 (51%), Gaps = 23/276 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
I G+FG V+ A TGD+ A+K +K D K S+ E ++ + +P +V+++
Sbjct: 760 ISRGAFGRVFLAKKRATGDLFAIKVLKKADM-IRKNAVESILAERNILISVRNPFVVRFF 818
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
R+ + + ME+ G L SLL + DE + ++Y +++ L LH ++HRD+
Sbjct: 819 YSFTCRENLYLVMEYLNGGDLFSLLRNLGCLDEDMARIYIAEVVLALEYLHSVNIIHRDL 878
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTG-------------GKD-- 1429
KP+N+L++++G IK DFG +K+ N + +S +++ ++G GKD
Sbjct: 879 KPDNLLINQDGHIKLTDFGLSKVGLINSTDDLSGESSLGNSGFFAEDGSKAQHSQGKDSR 938
Query: 1430 ----MIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHV 1485
++GTP Y+APE + G GHGK + D WS+G ++ E++ G P+ N + I ++
Sbjct: 939 KKHAVVGTPDYLAPEILLGMGHGK--TADWWSVGVILFEVLVGIPPF-NAETPQQIFENI 995
Query: 1486 AAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATA 1521
+P EIS I++ L ++ +R A
Sbjct: 996 INRDIPWPNVPEEISYEAHDLINKLLTENPVQRLGA 1031
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 126 bits (317), Expect = 2e-28
Identities = 81/276 (29%), Positives = 138/276 (49%), Gaps = 23/276 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
I G+FG V+ A TGD+ A+K +K D K S+ E ++ + +P +V+++
Sbjct: 896 ISRGAFGRVFLAKKRTTGDLFAIKVLKKADM-IRKNAVESILAERDILINVRNPFVVRFF 954
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
RD + + ME+ G L SLL + +E + +VY +++ L LH GVVHRD+
Sbjct: 955 YSFTCRDNLYLVMEYLNGGDLYSLLRNLGCLEEDIVRVYIAEVVLALEYLHSEGVVHRDL 1014
Query: 1385 KPENILLDRNGVIKYVDFGAAK-------------------LIAKNGSKRISLDANNKST 1425
KP+N+L+ +G IK DFG +K L+ + S+ + + +
Sbjct: 1015 KPDNLLIAHDGHIKLTDFGLSKVGLINSTDDLAGPAVSGTSLLDEEESRLAASEEQLERR 1074
Query: 1426 GGKDMIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHV 1485
+ +GTP Y+APE + G GHG + D WS+G ++ E++ G P+ N ++ I ++
Sbjct: 1075 KKRSAVGTPDYLAPEILLGTGHG--ATADWWSVGIILFELIVGIPPF-NAEHPQQIFDNI 1131
Query: 1486 AAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATA 1521
+P E+S+ I R L +D ++R A
Sbjct: 1132 LNRKIPWPHVPEEMSAEAHDIIDRFLTEDPHQRLGA 1167
>Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 820
Score = 126 bits (316), Expect = 3e-28
Identities = 84/278 (30%), Positives = 140/278 (50%), Gaps = 20/278 (7%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
R++ +G+G++G VY A + T ++ AVK +K+ + SL++E+ ++ H
Sbjct: 15 RFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDIS----SLQQEITILRECRH 70
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEH-GRIEDEMVTQVYTLQLLEGLACLHQ 1376
PN+V Y G + D++ I MEFC G SL + G +E+ + V + L+GL LH
Sbjct: 71 PNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCR-EALKGLHHLHS 129
Query: 1377 SGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
G +HRDIK N+LL G +K DFG + + + +KR + IGTP +
Sbjct: 130 QGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKR------------RSFIGTPYW 177
Query: 1437 MAPETVTGQGHGKFGS-DDIWSLGCVVLEMVTGRRPWANLDNEWAIM-YHVAAGHLPQFP 1494
MAPE + G + D+W+LG +E+ + P +L A+M ++ P+
Sbjct: 178 MAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLR 237
Query: 1495 TKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
K+ + F+ L ++ KR TA +LL P+ +Q
Sbjct: 238 DKTRWTQNFHHFLKLALTKNPKKRPTAEKLLQHPFTTQ 275
>Hs20070158 [T] KOG0201 Serine/threonine protein kinase
Length = 443
Score = 126 bits (316), Expect = 3e-28
Identities = 81/268 (30%), Positives = 137/268 (50%), Gaps = 25/268 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GSFG V+ ++ T ++A+K I +++A+ + +++E+ V+ + P + +YY
Sbjct: 42 IGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIE---DIQQEITVLSQCDSPYVTKYY 98
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTL--QLLEGLACLHQSGVVHR 1382
G + K+ I ME+ G S LLE G +++ TQ+ T+ ++L+GL LH +HR
Sbjct: 99 GSYLKDTKLWIIMEYLGGGSALDLLEPGPLDE---TQIATILREILKGLDYLHSEKKIHR 155
Query: 1383 DIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
DIK N+LL +G +K DFG A + KR +GTP +MAPE +
Sbjct: 156 DIKAANVLLSEHGEVKLADFGVAGQLTDTQIKR------------NTFVGTPFWMAPEVI 203
Query: 1443 TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSA 1502
+ DIWSLG +E+ G P + L + +++ + + P + S
Sbjct: 204 KQSAYD--SKADIWSLGITAIELARGEPPHSEL-HPMKVLFLIPKNNPPTL--EGNYSKP 258
Query: 1503 GRKFISRCLIQDANKRATAMELLLDPWI 1530
++F+ CL ++ + R TA ELL +I
Sbjct: 259 LKEFVEACLNKEPSFRPTAKELLKHKFI 286
>Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 302
Score = 126 bits (316), Expect = 3e-28
Identities = 75/259 (28%), Positives = 132/259 (50%), Gaps = 21/259 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G F VY A L G +A+K+++I D K +KE + +++ LNHPN+++YY
Sbjct: 40 IGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKE-IDLLKQLNHPNVIKYY 98
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQ----VYTLQLLEGLACLHQSGVV 1380
+ +++NI +E + L+ +++H + + ++ + Y +QL L +H V+
Sbjct: 99 ASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVM 158
Query: 1381 HRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPE 1440
HRDIKP N+ + GV+K D G + ++K+T ++GTP YM+PE
Sbjct: 159 HRDIKPANVFITATGVVKLGDLGLGRFF------------SSKTTAAHSLVGTPYYMSPE 206
Query: 1441 TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRP-WANLDNEWAIMYHVAAGHLPQFPTKSEI 1499
+ G+ DIWSLGC++ EM + P + + N +++ + P P+
Sbjct: 207 RIHENGYN--FKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPS-DHY 263
Query: 1500 SSAGRKFISRCLIQDANKR 1518
S R+ ++ C+ D KR
Sbjct: 264 SEELRQLVNMCINPDPEKR 282
>Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 336
Score = 126 bits (316), Expect = 3e-28
Identities = 87/288 (30%), Positives = 135/288 (46%), Gaps = 31/288 (10%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILN-H 1317
W+ IG G++G V+ +N G AVK + + I ++ E +++ L+ H
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILD-----PIHDIDEEIEAEYNILKALSDH 75
Query: 1318 PNIVQYYGVEVHRDKVN-----IFMEFCEGSSLASL----LEHGRIEDEMVTQVYTLQLL 1368
PN+V++YG+ +DKVN + +E C G S+ L L+ G E + + L
Sbjct: 76 PNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEAL 135
Query: 1369 EGLACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGK 1428
GL LH + +HRD+K NILL G +K VDFG + + +R
Sbjct: 136 MGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRR------------N 183
Query: 1429 DMIGTPMYMAPETVTGQGHGKFGSD---DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHV 1485
+GTP +MAPE + + D D WSLG +E+ G P A+L + ++ +
Sbjct: 184 TSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADL-HPMRALFKI 242
Query: 1486 AAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQI 1533
P+ S+ FIS+CL +D KR T ELL +I+QI
Sbjct: 243 PRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQI 290
>Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 336
Score = 126 bits (316), Expect = 3e-28
Identities = 87/288 (30%), Positives = 135/288 (46%), Gaps = 31/288 (10%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILN-H 1317
W+ IG G++G V+ +N G AVK + + I ++ E +++ L+ H
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILD-----PIHDIDEEIEAEYNILKALSDH 75
Query: 1318 PNIVQYYGVEVHRDKVN-----IFMEFCEGSSLASL----LEHGRIEDEMVTQVYTLQLL 1368
PN+V++YG+ +DKVN + +E C G S+ L L+ G E + + L
Sbjct: 76 PNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEAL 135
Query: 1369 EGLACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGK 1428
GL LH + +HRD+K NILL G +K VDFG + + +R
Sbjct: 136 MGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRR------------N 183
Query: 1429 DMIGTPMYMAPETVTGQGHGKFGSD---DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHV 1485
+GTP +MAPE + + D D WSLG +E+ G P A+L + ++ +
Sbjct: 184 TSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADL-HPMRALFKI 242
Query: 1486 AAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQI 1533
P+ S+ FIS+CL +D KR T ELL +I+QI
Sbjct: 243 PRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQI 290
>HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 819
Score = 125 bits (315), Expect = 4e-28
Identities = 84/278 (30%), Positives = 140/278 (50%), Gaps = 20/278 (7%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
R++ +G+G++G VY A + T ++ AVK +K+ + SL++E+ ++ H
Sbjct: 14 RFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDIS----SLQQEITILRECRH 69
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEH-GRIEDEMVTQVYTLQLLEGLACLHQ 1376
PN+V Y G + D++ I MEFC G SL + G +E+ + V + L+GL LH
Sbjct: 70 PNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCR-ERLKGLHHLHS 128
Query: 1377 SGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
G +HRDIK N+LL G +K DFG + + + +KR + IGTP +
Sbjct: 129 QGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKR------------RSFIGTPYW 176
Query: 1437 MAPETVTGQGHGKFGS-DDIWSLGCVVLEMVTGRRPWANLDNEWAIM-YHVAAGHLPQFP 1494
MAPE + G + D+W+LG +E+ + P +L A+M ++ P+
Sbjct: 177 MAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLR 236
Query: 1495 TKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
K+ + F+ L ++ KR TA +LL P+ +Q
Sbjct: 237 DKTRWTQNFHHFLKLALTKNPKKRPTAEKLLQHPFTTQ 274
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 125 bits (315), Expect = 4e-28
Identities = 80/275 (29%), Positives = 135/275 (49%), Gaps = 20/275 (7%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
+++ +G G+F VY + G+ +A+K I + +K E+ +M+++ H
Sbjct: 11 KYEMGRLLGKGTFAKVYYGKEIIGGECVAIKVINKDQVMKRPGMMEQIKREISIMKLVRH 70
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
PNIV+ V + K+ MEF +G L + G++ ++ + Y QL+ + H
Sbjct: 71 PNIVELKEVMATKTKIFFVMEFVKGGELFCKISKGKLHEDAARR-YFQQLISAVDYCHSR 129
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
GV HRD+KPEN+LLD NG +K DFG + L ++I D + GTP Y+
Sbjct: 130 GVSHRDLKPENLLLDENGDLKISDFGLSAL-----PEQILQDGLLHT-----QCGTPAYV 179
Query: 1438 APETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW--ANLDNEWAIMYHVAAGHLPQFPT 1495
APE + +G+ DIWS G V+ ++ G P+ NL N + ++ P F
Sbjct: 180 APEVLKKKGYDG-AKADIWSCGVVLYVLLAGCLPFQDENLMNMYRKIFRADFEFPPWF-- 236
Query: 1496 KSEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
S R+ IS+ L+ D ++R + ++ PW+
Sbjct: 237 ----SPEARRLISKLLVVDPDRRISIPAIMRTPWL 267
>Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 527
Score = 125 bits (314), Expect = 5e-28
Identities = 89/295 (30%), Positives = 139/295 (46%), Gaps = 27/295 (9%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHP 1318
++ + IGSG+ V +A + +A+K I ++ ++ L +E++ M +HP
Sbjct: 17 YELQEVIGSGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMD---ELLKEIQAMSQCHHP 73
Query: 1319 NIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEH--------GRIEDEMVTQVYTLQLLEG 1370
NIV YY V +D++ + M+ G S+ +++H + DE ++LEG
Sbjct: 74 NIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEG 133
Query: 1371 LACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDM 1430
L LH++G +HRD+K NILL +G ++ DFG + +A G ++ K
Sbjct: 134 LEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGD-------ITRNKVRKTF 186
Query: 1431 IGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHL 1490
+GTP +MAPE V Q G DIWS G +E+ TG P+ +M
Sbjct: 187 VGTPCWMAPE-VMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLML-TLQNDP 244
Query: 1491 PQFPT----KSEISSAG---RKFISRCLIQDANKRATAMELLLDPWISQIRNIAF 1538
P T K + G RK IS CL +D KR TA ELL + + +N F
Sbjct: 245 PSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEF 299
>At3g50310 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 342
Score = 124 bits (312), Expect = 9e-28
Identities = 93/278 (33%), Positives = 142/278 (50%), Gaps = 28/278 (10%)
Query: 1259 WQKRSFIGSGSFGTVYSAV-NLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
W + IG G+F TV +A + ++GD A+ +K DA SL E V++ L
Sbjct: 3 WVRGETIGFGTFSTVSTATKSRNSGDFPALIAVKSTDAYGAA----SLSNEKSVLDSLGD 58
Query: 1318 -PNIVQYYG----VEVHRDKVNIFMEFCEGSSLASLLEH--GRIEDEMVTQVYTLQLLEG 1370
P I++ YG VE + N+ +E+ SLAS ++ G E + +T +L G
Sbjct: 59 CPEIIRCYGEDSTVENGEEMHNLLLEYASRGSLASYMKKLGGEGLPESTVRRHTGSVLRG 118
Query: 1371 LACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDM 1430
L +H G H DIK NILL +G +K DFG A + + L A KS ++
Sbjct: 119 LRHIHAKGFAHCDIKLANILLFNDGSVKIADFGLAMRVDGD------LTALRKSV---EI 169
Query: 1431 IGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNE--WAIMYHVAAG 1488
GTP+YMAPE V +G + D+W+LGC V+EM +G+ W+ + +++ + G
Sbjct: 170 RGTPLYMAPECVNDNEYG--SAADVWALGCAVVEMFSGKTAWSVKEGSHFMSLLIRIGVG 227
Query: 1489 -HLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELL 1525
LP+ P +S G+ F+S+C ++D KR TA LL
Sbjct: 228 DELPKIP--EMLSEEGKDFLSKCFVKDPAKRWTAEMLL 263
>At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 284
Score = 124 bits (312), Expect = 9e-28
Identities = 97/275 (35%), Positives = 142/275 (51%), Gaps = 27/275 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPS--LKEEMRVMEILN-HPNIV 1321
IG G FGTV TGD A K I D S+ L E ++M +L+ HPNIV
Sbjct: 21 IGRGRFGTVSRVYAPATGDFFACKTI---DKASLSDDLDRACLDNEPKLMALLSYHPNIV 77
Query: 1322 QYYGVEVHRDKVNIFMEFCEGS-SLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVV 1380
Q + + ++IFME S S+ L E T + Q+L+ L+ H+ GVV
Sbjct: 78 QIHDLIDTDSTLSIFMELVHPSVSIYDRLVSSGTFFEPQTASFAKQILQALSHCHRYGVV 137
Query: 1381 HRDIKPENILLD-RNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAP 1439
HRDIKPENIL+D RN +K DFG+ + + ++T G ++GTP Y+AP
Sbjct: 138 HRDIKPENILVDLRNDTVKICDFGSGIWLGE-----------GETTEG--VVGTPYYVAP 184
Query: 1440 ETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTK--S 1497
E + G +G+ D+WS G V+ M+ G P+ E I V G+L +FPTK
Sbjct: 185 EVLMGYSYGE--KVDLWSAGVVLYTMLAGTPPFYGETAE-EIFEAVLRGNL-RFPTKIFR 240
Query: 1498 EISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
+SS + F+ + + +DA++R +A + L PWI +
Sbjct: 241 GVSSMAKDFLRKLICKDASRRFSAEQALRHPWIQR 275
>SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 722
Score = 124 bits (311), Expect = 1e-27
Identities = 89/296 (30%), Positives = 140/296 (47%), Gaps = 44/296 (14%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GSFG +Y L G +LA KEI + ++ + + +E+ ++ L HPNIVQY
Sbjct: 10 IGHGSFGRIYKVQRLKDGALLAQKEIHFGNITRQEKQY--IADEVNILRNLKHPNIVQYC 67
Query: 1325 GVEVHRDK--VNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTL----QLLEGLACLH--- 1375
G E++R +N++ME+C LA+L++ + E + T+ L QLL L H
Sbjct: 68 GEELNRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLLLALYRCHYGE 127
Query: 1376 ----------------QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLD 1419
+ V+HRDIKP NI LD N +K DFG +KL+
Sbjct: 128 NAPACDSQWPREIFHPKQSVLHRDIKPANIFLDENNSVKLGDFGLSKLL----------- 176
Query: 1420 ANNKSTGGKDMIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEW 1479
+N + +GTP YM+PE + + D+W+LGCV+ E+ P+ +
Sbjct: 177 -DNTRVFTQSYVGTPYYMSPEIIRSSPYS--AKSDVWALGCVIFEICMLTHPFEG-RSYL 232
Query: 1480 AIMYHVAAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRN 1535
+ ++ G+L + S I CL +++ R T +LL P +S IR+
Sbjct: 233 ELQRNICQGNLSCW--DHHYSDDVFLLIRHCLEVNSDLRPTTYQLLRSPILSDIRS 286
>At2g30040 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 463
Score = 124 bits (310), Expect = 2e-27
Identities = 88/287 (30%), Positives = 150/287 (51%), Gaps = 32/287 (11%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEIL-NH 1317
W + S +G G FGTV A++ G + AVK I + A + SL+ E+ ++ + +H
Sbjct: 17 WIRGSCVGRGCFGTVSKALSKIDGGLFAVKSIDL--ATCLPSQAESLENEIVILRSMKSH 74
Query: 1318 PNIVQYYGVEVHRDKV----NIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLAC 1373
PNIV++ G +V ++ N+ +E+ +A+ G I +E + + Y L+ L+
Sbjct: 75 PNIVRFLGDDVSKEGTASFRNLHLEYSPEGDVAN----GGIVNETLLRRYVWCLVSALSH 130
Query: 1374 LHQSGVVHRDIKPENILLDRNG-VIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIG 1432
+H +G+VH D+K +N+L+ G +K DFG+A KST G
Sbjct: 131 VHSNGIVHCDVKSKNVLVFNGGSSVKLADFGSAVEF-------------EKSTIHVSPRG 177
Query: 1433 TPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVA-AGHLP 1491
+P++MAPE V + G D+WSLGC V+EM+TG+ W D+ + + + + LP
Sbjct: 178 SPLWMAPEVVRREYQGP--ESDVWSLGCTVIEMLTGKPAWE--DHGFDSLSRIGFSNDLP 233
Query: 1492 QFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNIAF 1538
P +S GR F+ +CL +D ++R + +LL P++ Q + +F
Sbjct: 234 FIPV--GLSELGRDFLEKCLKRDRSQRWSCDQLLQHPFLCQDHHDSF 278
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 123 bits (308), Expect = 3e-27
Identities = 75/210 (35%), Positives = 115/210 (54%), Gaps = 22/210 (10%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G+GSFG V+ ++ G A+K +K Q MKQ+ +E R+++++ HP +++ +
Sbjct: 76 LGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQV-EHTNDERRMLKLVEHPFLIRMW 134
Query: 1325 GVEVHRDKVNIFM--EFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHR 1382
G +D NIFM ++ EG L SLL + V + Y +++ L LH +++R
Sbjct: 135 GT--FQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYR 192
Query: 1383 DIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
D+KPENILLDRNG IK DFG AK + T + GTP Y+APE +
Sbjct: 193 DLKPENILLDRNGHIKITDFGFAKEV---------------QTVTWTLCGTPDYIAPEVI 237
Query: 1443 TGQGHGKFGSDDIWSLGCVVLEMVTGRRPW 1472
T + + K S D WSLG ++ EM+ G P+
Sbjct: 238 TTKPYNK--SVDWWSLGVLIYEMLAGYTPF 265
>CE28674 [T] KOG0201 Serine/threonine protein kinase
Length = 651
Score = 123 bits (308), Expect = 3e-27
Identities = 77/274 (28%), Positives = 141/274 (51%), Gaps = 20/274 (7%)
Query: 1261 KRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNI 1320
K+ IG GSFG VY ++ TG ++A+K I ++ A+ + +++E++V+ + +
Sbjct: 34 KQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIE---DIQQEIQVLSQCDSQYV 90
Query: 1321 VQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVV 1380
+Y+G + K+ I ME+ G S L + G++++ + V ++L+GL LH +
Sbjct: 91 TKYFGSFLKGSKLWIIMEYLGGGSALDLTKSGKLDESHIA-VILREILKGLEYLHSERKI 149
Query: 1381 HRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPE 1440
HRDIK N+L+ +G +K DFG A + + KRI+ +G+P +MAPE
Sbjct: 150 HRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRIT------------FVGSPFWMAPE 197
Query: 1441 TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEIS 1500
+ + DIWSLG +E+ G P ++L + +++ + + P S+ S
Sbjct: 198 LIKQSSYDY--KADIWSLGITAIELANGEPPHSDL-HPMRVLFLIPK-NPPPVLQGSQWS 253
Query: 1501 SAGRKFISRCLIQDANKRATAMELLLDPWISQIR 1534
++F+ CL +D R +A LL +I + +
Sbjct: 254 KPFKEFVEMCLNKDPENRPSASTLLKHQFIKRAK 287
>CE07510 [T] KOG0201 Serine/threonine protein kinase
Length = 653
Score = 123 bits (308), Expect = 3e-27
Identities = 77/274 (28%), Positives = 141/274 (51%), Gaps = 20/274 (7%)
Query: 1261 KRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNI 1320
K+ IG GSFG VY ++ TG ++A+K I ++ A+ + +++E++V+ + +
Sbjct: 36 KQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIE---DIQQEIQVLSQCDSQYV 92
Query: 1321 VQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVV 1380
+Y+G + K+ I ME+ G S L + G++++ + V ++L+GL LH +
Sbjct: 93 TKYFGSFLKGSKLWIIMEYLGGGSALDLTKSGKLDESHIA-VILREILKGLEYLHSERKI 151
Query: 1381 HRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPE 1440
HRDIK N+L+ +G +K DFG A + + KRI+ +G+P +MAPE
Sbjct: 152 HRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRIT------------FVGSPFWMAPE 199
Query: 1441 TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEIS 1500
+ + DIWSLG +E+ G P ++L + +++ + + P S+ S
Sbjct: 200 LIKQSSYDY--KADIWSLGITAIELANGEPPHSDL-HPMRVLFLIPK-NPPPVLQGSQWS 255
Query: 1501 SAGRKFISRCLIQDANKRATAMELLLDPWISQIR 1534
++F+ CL +D R +A LL +I + +
Sbjct: 256 KPFKEFVEMCLNKDPENRPSASTLLKHQFIKRAK 289
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 123 bits (308), Expect = 3e-27
Identities = 84/276 (30%), Positives = 141/276 (50%), Gaps = 19/276 (6%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQ-IFPSLKEEMRVMEILN 1316
R++ +G G+F VY A N+ T + +A+K I + K +K + +K E+ ++ +
Sbjct: 25 RYEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDKE--KVLKGGLIAHIKREISILRRVR 82
Query: 1317 HPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQ 1376
HPNIVQ + V + K+ ME+ G L + + GR+++E V + Y QL+ + H
Sbjct: 83 HPNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAKGRLKEE-VARKYFQQLISAVTFCHA 141
Query: 1377 SGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
GV HRD+KPEN+LLD NG +K DFG + + S +I D + GTP Y
Sbjct: 142 RGVYHRDLKPENLLLDENGNLKVSDFGLSAV-----SDQIRQDGLFHT-----FCGTPAY 191
Query: 1437 MAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTK 1496
+APE + +G+ DIWS G ++ ++ G P+ + N A+ + G +F
Sbjct: 192 VAPEVLARKGYDA-AKVDIWSCGVILFVLMAGYLPFHD-RNVMAMYKKIYRG---EFRCP 246
Query: 1497 SEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
S+ + +S+ L + KR T E++ + W +
Sbjct: 247 RWFSTELTRLLSKLLETNPEKRFTFPEIMENSWFKK 282
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 123 bits (308), Expect = 3e-27
Identities = 91/325 (28%), Positives = 159/325 (48%), Gaps = 54/325 (16%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKE-IKIQDAKSMKQIFPSLKEEMRVMEILN 1316
R++K S +G GS+G VY + +TG ++AVK ++ +D ++++I E+R+++ L
Sbjct: 3 RYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKI---ALREIRLLKNLK 59
Query: 1317 HPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQ 1376
HPN+V V + ++++ EFCE + L L H + E +T+ Q L G+A H+
Sbjct: 60 HPNLVSLLEVFRRKRRLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCHK 119
Query: 1377 SGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
G +HRDIKPENILL G +K DFG A++++ + D + T Y
Sbjct: 120 QGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGENY-------------TDYVATRWY 166
Query: 1437 MAPETVTGQGHGKFGSD-DIWSLGCVVLEMVTGRRPW---ANLDNEWAI---MYHVAAGH 1489
APE + G ++G+ D+W++GC+ E+V G W +++D + I + + H
Sbjct: 167 RAPELLVGD--TQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRH 224
Query: 1490 LPQF------------------------PTKSEISSAGRKFISRCLIQDANKRATAMEL- 1524
+ F P KS+ + F+ +CL +D KR + +L
Sbjct: 225 IQIFGQNEYFKGITLPVPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLT 284
Query: 1525 ---LLDPWISQIRNIAFGGNAESFN 1546
D +I++ R + + E+ N
Sbjct: 285 KHSYFDDYIAKQRELEHVNSLEAAN 309
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 122 bits (307), Expect = 3e-27
Identities = 72/208 (34%), Positives = 114/208 (54%), Gaps = 16/208 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G G+FG VY DT +I A+K ++ +D K +K E ++ ++HP IVQ
Sbjct: 146 VGQGAFGKVYQVRKKDTSEIYAMKVMR-KDKIVEKNHAEYMKAERDILTKIDHPFIVQLK 204
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ ++ + ++F G L L H + E + +VYT +++ ++ LH+ G++HRD+
Sbjct: 205 YSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDL 264
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
KPENIL+D +G + DFG AK +N T M GT YMAPE V G
Sbjct: 265 KPENILMDVDGHVMLTDFGLAKEFEEN-------------TRSNSMCGTTEYMAPEIVRG 311
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPW 1472
+GH K + D WS+G ++ EM+TG+ P+
Sbjct: 312 KGHDK--AADWWSVGILLYEMLTGKPPF 337
>At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1067
Score = 122 bits (307), Expect = 3e-27
Identities = 83/274 (30%), Positives = 132/274 (47%), Gaps = 23/274 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
I G+FG V+ A TGD A+K +K D I + +E ++ + +P +V+++
Sbjct: 676 ISRGAFGKVFLARKRTTGDFFAIKVLKKLDMIRKNDI-ERILQERNILITVRYPFLVRFF 734
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
RD + + ME+ G L SLL+ DE + ++Y +L+ L LH +VHRD+
Sbjct: 735 YSFTCRDNLYLVMEYLNGGDLYSLLQKVGCLDEEIARIYIAELVLALEYLHSLKIVHRDL 794
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGK---------------- 1428
KP+N+L+ NG IK DFG +K+ N + I L + +
Sbjct: 795 KPDNLLIAYNGHIKLTDFGLSKIGLINNT--IDLSGHESDVSPRTNSHHFQKNQEEERIR 852
Query: 1429 -DMIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAA 1487
+GTP Y+APE + G HG + D WS G V+ E++TG P+ E I ++
Sbjct: 853 HSAVGTPDYLAPEILLGTEHGY--AADWWSAGIVLFELLTGIPPFTASRPE-KIFDNILN 909
Query: 1488 GHLPQFPTKSEISSAGRKFISRCLIQDANKRATA 1521
G +P E+S + I+R L+ + KR A
Sbjct: 910 GKMPWPDVPGEMSYEAQDLINRLLVHEPEKRLGA 943
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 122 bits (306), Expect = 4e-27
Identities = 94/316 (29%), Positives = 151/316 (47%), Gaps = 63/316 (19%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKE-IKIQDAKSMKQIFPSLKEEMRVMEILN 1316
++ + S +G GS+G VY N DTG I+A+K+ ++ +D +K+I E+R+++ L
Sbjct: 3 KYDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKI---ALREIRMLKQLK 59
Query: 1317 HPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLE--HGRIEDEMVTQVYTLQLLEGLACL 1374
H N+V V K+++ E C+ + L L + HG + DE++ ++ QLLE L
Sbjct: 60 HQNLVGLIEVFKRNRKLHLVFELCDRTVLHELEKNPHG-VNDELIKKII-YQLLEALKFC 117
Query: 1375 HQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
H +HRD+KPENI L RN +K DFG A++I N + D + T
Sbjct: 118 HSHKCIHRDVKPENIFLTRNDQVKLGDFGFARII-------------NTTEMYTDYVATR 164
Query: 1435 MYMAPETVTGQGHGKFGSD-DIWSLGCVVLEMVTGRRPW---ANLDNEWAIMYHV----- 1485
Y +PE + G ++G DIW++GCV E++TG W +++D +YH+
Sbjct: 165 WYRSPELLVGD--VQYGPPVDIWAVGCVYAELLTGEALWPGRSDIDQ----LYHIRKTLG 218
Query: 1486 ----------------------AAGHLPQFPTK-SEISSAGRKFISRCLIQDANKRATAM 1522
HL P+K SSA F+ +C ++R +
Sbjct: 219 EFLPRHISIFRTNQFFFGLSIPEPEHLEPLPSKLPNASSAQLDFLQKCFEMSPDRRFSCS 278
Query: 1523 ELLL----DPWISQIR 1534
EL+L WI +IR
Sbjct: 279 ELMLHGIFSNWILRIR 294
>Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1152
Score = 122 bits (305), Expect = 6e-27
Identities = 87/277 (31%), Positives = 134/277 (47%), Gaps = 21/277 (7%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHP 1318
W+ +G G+FG VY A N +T + A K I D KS +++ E+ ++ +HP
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVI---DTKSEEEL-EDYMVEIDILASCDHP 89
Query: 1319 NIVQYYGVEVHRDKVNIFMEFCEGSSL-ASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
NIV+ + + + I +EFC G ++ A +LE R E QV Q L+ L LH +
Sbjct: 90 NIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDN 149
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
++HRD+K NIL +G IK DFG + + +R S IGTP +M
Sbjct: 150 KIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDS------------FIGTPYWM 197
Query: 1438 APETV---TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFP 1494
APE V T + D+WSLG ++EM P L N ++ +A P
Sbjct: 198 APEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHEL-NPMRVLLKIAKSEPPTLA 256
Query: 1495 TKSEISSAGRKFISRCLIQDANKRATAMELLLDPWIS 1531
S SS + F+ +CL ++ + R T +LL P+++
Sbjct: 257 QPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVT 293
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 122 bits (305), Expect = 6e-27
Identities = 71/208 (34%), Positives = 114/208 (54%), Gaps = 16/208 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G G+FG VY +T +I A+K ++ +D K +K E ++ ++HP IVQ
Sbjct: 140 VGKGAFGKVYQVRKKETSEIYAMKVMR-KDHIMEKNHAEYMKAERDILTKIDHPFIVQLK 198
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ ++ + ++F G L L H + E + +VYT +++ ++ LH+ G++HRD+
Sbjct: 199 YSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDL 258
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
KPENIL+D +G + DFG AK +N T M GT YMAPE V G
Sbjct: 259 KPENILMDTDGHVMLTDFGLAKEFEEN-------------TRSNSMCGTTEYMAPEIVRG 305
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPW 1472
+GH K + D WS+G ++ EM+TG+ P+
Sbjct: 306 KGHDK--AADWWSVGILLYEMLTGKPPF 331
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 122 bits (305), Expect = 6e-27
Identities = 82/266 (30%), Positives = 129/266 (47%), Gaps = 20/266 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G G FG VY A + I+A+K I + + K I L+ EM + L HPNI++ +
Sbjct: 28 LGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKYK-IHHQLRREMEIQTSLRHPNILRLF 86
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G +++ + +E+ G L +L+ E Y L + LA H V+HRDI
Sbjct: 87 GWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASLSQALAYCHGKCVIHRDI 146
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
KPEN+LLD G +K DFG S+ ++NK K M GT Y+APE V
Sbjct: 147 KPENLLLDHEGRLKIADFG------------WSVQSSNKR---KTMCGTLDYLAPEMVEN 191
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+ H + D W+LG + E + G P+ +++ + L FP +S +
Sbjct: 192 RDHDY--AVDNWTLGILCYEFLYGNPPF-EAESQKDTFKRILKIDL-SFPLTPNVSEEAK 247
Query: 1505 KFISRCLIQDANKRATAMELLLDPWI 1530
IS+ L++D +KR + +++ PWI
Sbjct: 248 NLISQLLVKDPSKRLSIEKIMQHPWI 273
>Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 476
Score = 121 bits (303), Expect = 1e-26
Identities = 88/279 (31%), Positives = 139/279 (49%), Gaps = 25/279 (8%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHP 1318
W +G G++G V AVN T + +AVK I D K ++K+E+ + ++LNH
Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVK---IVDMKRAVDCPENIKKEICINKMLNHE 65
Query: 1319 NIVQYYGVEVHRDKVNI---FMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLH 1375
N+V++YG HR + NI F+E+C G L +E E Q + QL+ G+ LH
Sbjct: 66 NVVKFYG---HRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
Query: 1376 QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
G+ HRDIKPEN+LLD +K DFG A + N +R+ NK M GT
Sbjct: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLL----NK------MCGTLP 172
Query: 1436 YMAPETVTGQGHGKFGSD--DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQF 1493
Y+APE + + +F ++ D+WS G V+ M+ G PW + ++ Y
Sbjct: 173 YVAPELLKRR---EFHAEPVDVWSCGIVLTAMLAGELPW-DQPSDSCQEYSDWKEKKTYL 228
Query: 1494 PTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
+I SA + + L+++ + R T ++ D W ++
Sbjct: 229 NPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNK 267
>CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 1101
Score = 121 bits (303), Expect = 1e-26
Identities = 88/272 (32%), Positives = 140/272 (51%), Gaps = 27/272 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEI-KIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQY 1323
+GSG FGTVY ++ G +AVK I K++ + + + L+ E++++E ++HP +V +
Sbjct: 776 LGSGQFGTVYGGIHRRNGQHVAVKLIDKLKFPPNKEDL---LRAEVQILEKVDHPGVVHF 832
Query: 1324 YGVEVHRDKVNIFMEFCEGSSLASLL--EHGRIEDEMVTQVYTLQLLEGLACLHQSGVVH 1381
+ D++ + ME +G L +L E GR+ E TQ Q+LE L LH +VH
Sbjct: 833 MQMLETTDRIFVVMEKLKGDMLEMILSSEKGRLS-ERTTQFLVAQILEALRYLHHLNIVH 891
Query: 1382 RDIKPENILLDRNG---VIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMA 1438
D+KPENILL+ N +K DFG A++I + +R ++GTP Y+A
Sbjct: 892 CDLKPENILLNSNSDFPQVKLCDFGFARIIGEKSFRR-------------SVVGTPAYLA 938
Query: 1439 PETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSE 1498
PE + +G + S D+WS+G +V ++G P+ N D + A P P K E
Sbjct: 939 PEVLRNKGFNR--SLDMWSVGVIVYVSLSGTFPF-NEDEDINDQIQNAEFMYPPTPWK-E 994
Query: 1499 ISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
IS +FI+ L +KR T + W+
Sbjct: 995 ISENAIEFINGLLQVKMSKRYTVTKAQSQIWM 1026
>At1g73500 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 310
Score = 120 bits (302), Expect = 1e-26
Identities = 89/282 (31%), Positives = 146/282 (51%), Gaps = 30/282 (10%)
Query: 1260 QKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFP-SLKEEMRVMEILNHP 1318
+K + +G G+ G VY + T +I A+K + M IF L EM ++ + P
Sbjct: 48 EKLNVLGCGNGGIVYKVRHKTTSEIYALKTVN----GDMDPIFTRQLMREMEILRRTDSP 103
Query: 1319 NIVQYYGV--EVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQ 1376
+V+ +G+ + +V+I ME+ +G +L SL G + ++ + + Q+L+GL+ LH
Sbjct: 104 YVVKCHGIFEKPVVGEVSILMEYMDGGTLESL--RGGVTEQKLAG-FAKQILKGLSYLHA 160
Query: 1377 SGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
+VHRDIKP N+LL+ +K DFG +K++ + SLD+ N +GT Y
Sbjct: 161 LKIVHRDIKPANLLLNSKNEVKIADFGVSKILVR------SLDSCN------SYVGTCAY 208
Query: 1437 MAPETVTGQ---GHGKFGSDDIWSLGCVVLEMVTGRRPW--ANLDNEWA-IMYHVAAGHL 1490
M+PE + G + DIWS G ++LE++ G P +WA +M V G
Sbjct: 209 MSPERFDSESSGGSSDIYAGDIWSFGLMMLELLVGHFPLLPPGQRPDWATLMCAVCFGEP 268
Query: 1491 PQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
P+ P S R F+ CL +D++KR TA +LL P++ +
Sbjct: 269 PRAP--EGCSEEFRSFVECCLRKDSSKRWTAPQLLAHPFLRE 308
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 446
Score = 120 bits (301), Expect = 2e-26
Identities = 84/273 (30%), Positives = 141/273 (50%), Gaps = 23/273 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G+G+FG V A N +TG+ +AVK + + K K +L +E+ +++ L+HPNIV +
Sbjct: 43 LGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFK 102
Query: 1325 GVEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
+DK I + +G L +L+ G+ +E ++ +++L + +H +VHRD
Sbjct: 103 DWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRI-LVEILSAVKYMHSQNIVHRD 161
Query: 1384 IKPENIL-LDRN--GVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPE 1440
+KPEN+L +D++ + DFG AK + K+ + + A G+ Y+APE
Sbjct: 162 LKPENLLYIDKSDESPLVVADFGIAKRL-KSDEELLYKPA-----------GSLGYVAPE 209
Query: 1441 TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLP---QFPTKS 1497
+T GHGK DIWS+G + ++ G + + + G P P
Sbjct: 210 VLTQDGHGK--PCDIWSIGVITYTLLCGYSAF-RAERVQDFLDECTTGEYPVKFHRPYWD 266
Query: 1498 EISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+S+ ++FI + L D +KR TA ELL DPWI
Sbjct: 267 SVSNKAKQFILKALNLDPSKRPTAAELLEDPWI 299
>SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase
Length = 652
Score = 120 bits (301), Expect = 2e-26
Identities = 84/278 (30%), Positives = 142/278 (50%), Gaps = 25/278 (8%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKI---QDAKSMKQIFPSLKEEMRVMEIL 1315
+ K +G GS+G VY + T + +A+K + + +D S Q ++ E++ ++
Sbjct: 10 YTKLELVGRGSYGAVYRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQSDV- 68
Query: 1316 NHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLH 1375
NI++Y+G + + I M++C G S+ +L+E G I + ++ + + L+ L +H
Sbjct: 69 --ENIIKYHGSYLVGTNLWIIMDYCHGGSVRTLMEAGPISEPCISLILR-ETLQALKFIH 125
Query: 1376 QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
+G++HRDIK NIL+ +G +K DFG A + N KRI+ IGTP
Sbjct: 126 HAGIIHRDIKAANILVSMSGNVKLCDFGVAAELNINRRKRIT------------FIGTPY 173
Query: 1436 YMAPETV-TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFP 1494
+MAPE + GQ + DIWSLG E+ TG P A ++ + +Y +A P+
Sbjct: 174 WMAPEVIRDGQEYNVMA--DIWSLGITAYEIATGSPPHAK-EDPFRAVYLIAHTAPPRL- 229
Query: 1495 TKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
S+ ++FI+ CL +R + ELL +I Q
Sbjct: 230 -NGNFSALLKEFIASCLQDVPQRRLDSSELLKSKFIKQ 266
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 120 bits (300), Expect = 2e-26
Identities = 82/277 (29%), Positives = 143/277 (51%), Gaps = 26/277 (9%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEI---KIQDAKSMKQIFPSLKEEMRVMEI 1314
R++ + +G G++G V A +G ++A+K I KI+D + M I + E+ +M
Sbjct: 54 RYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHI----RREIEIMSS 109
Query: 1315 LNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACL 1374
LNHP+I+ Y V ++DK+ I ME+ L + R E T+ + Q++ +
Sbjct: 110 LNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYC 169
Query: 1375 HQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
H++GVVHRD+K ENILLD N IK DFG + L K+ + G+P
Sbjct: 170 HKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFL-------------QTFCGSP 216
Query: 1435 MYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFP 1494
+Y +PE V G+ + + D W+LG ++ +V G P+ D++ ++ +++G + P
Sbjct: 217 LYASPEIVNGRPY-RGPEVDSWALGVLLYTLVYGTMPFDGFDHK-NLIRQISSGEYRE-P 273
Query: 1495 TKSEISSAGRKFISRCLIQDANKRATAMELLLDPWIS 1531
T+ S R I L+ + ++RAT ++ W++
Sbjct: 274 TQ---PSDARGLIRWMLMVNPDRRATIEDIANHWWVN 307
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 120 bits (300), Expect = 2e-26
Identities = 82/286 (28%), Positives = 140/286 (48%), Gaps = 30/286 (10%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G G+F V A N++ GD +A+K I + K I +K E+ M+++ HPN+++ +
Sbjct: 37 LGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKNKMI-AQIKREISTMKLIKHPNVIRMF 95
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLE-HGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
V + K+ +EF G L + +GR++++ + Y QL+ + H GV HRD
Sbjct: 96 EVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARK-YFQQLINAVDYCHSRGVYHRD 154
Query: 1384 IKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVT 1443
+KPEN+LLD NG +K DFG + L + D +T GTP Y+APE +
Sbjct: 155 LKPENLLLDANGALKVSDFGLSALPQQE-------DGLLHTT-----CGTPNYVAPEVIN 202
Query: 1444 GQGHGKFGSDDIWSLGCVVLEMVTGRRPW--ANLDNEWAIMYHVAAGHLPQFPTKSEISS 1501
+G+ D+WS G ++ ++ G P+ +NL + + ++ +F S+
Sbjct: 203 NKGYDG-AKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKA------EFTCPPWFSA 255
Query: 1502 AGRKFISRCLIQDANKRATAMELLLDPWISQIRNIAFGGNAESFNN 1547
+ +K I R L + R T E++ + W + G A F N
Sbjct: 256 SAKKLIKRILDPNPATRITFAEVIENEWFKK------GYKAPKFEN 295
>Hs15011880 [T] KOG0201 Serine/threonine protein kinase
Length = 416
Score = 119 bits (299), Expect = 3e-26
Identities = 78/266 (29%), Positives = 130/266 (48%), Gaps = 21/266 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GSFG V+ ++ T ++A+K I +++A+ + +++E+ V+ + + +YY
Sbjct: 30 IGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIE---DIQQEITVLSQCDSSYVTKYY 86
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G + K+ I ME+ G S LL G DE ++L+GL LH +HRDI
Sbjct: 87 GSYLKGSKLWIIMEYLGGGSALDLLRAGPF-DEFQIATMLKEILKGLDYLHSEKKIHRDI 145
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K N+LL G +K DFG A + KR +GTP +MAPE +
Sbjct: 146 KAANVLLSEQGDVKLADFGVAGQLTDTQIKR------------NTFVGTPFWMAPEVIQQ 193
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+ DIWSLG +E+ G P +++ + +++ + + P + + + +
Sbjct: 194 SAYD--SKADIWSLGITAIELAKGEPPNSDM-HPMRVLFLIPKNNPPTL--VGDFTKSFK 248
Query: 1505 KFISRCLIQDANKRATAMELLLDPWI 1530
+FI CL +D + R TA ELL +I
Sbjct: 249 EFIDACLNKDPSFRPTAKELLKHKFI 274
>At3g45670 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 379
Score = 119 bits (299), Expect = 3e-26
Identities = 97/301 (32%), Positives = 149/301 (49%), Gaps = 41/301 (13%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHP 1318
W K +G G++G VY A + D DI E I+ A +K SL E R++ L P
Sbjct: 97 WVKSRLLGEGAYGCVYLATSKD--DIYKT-ERAIKSADVLKAW--SLMHEGRILRSLQSP 151
Query: 1319 NIVQYYGVEVHRD----KVNIFMEFCEGSSLASLLE--HGRIEDEMVTQVYTLQLLEGLA 1372
+++ YG E+ R+ + N+ +E+C G LA ++E G I + V Q + + +L GL+
Sbjct: 152 FVIRCYGHEIAREGTGHQYNLILEYCSGQCLADMIEDNQGGIPEFDVKQ-FAIDVLSGLS 210
Query: 1373 CLHQSGVVHRDIKPENILLD-------RNGVI-KYVDFGAAKLIAKNGSKRISLDANNKS 1424
+H+ ++H +IKP+N+LL NG + K DFG L + GSK
Sbjct: 211 YIHRRNIIHCEIKPDNLLLSPVDHRFRSNGFLTKIADFG---LSMEKGSKEY-------G 260
Query: 1425 TGGKDMIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWAN----LDNEWA 1480
G M GT YMAPE + G G F + DI + GC VLEM+TG+R W ++W
Sbjct: 261 NGRGHMRGTTRYMAPELI-GGGLLDF-AVDICAFGCSVLEMLTGKRVWGEYGDLAHDDWV 318
Query: 1481 IMYHVAAGHLPQFPTKS-EISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNIAFG 1539
+ GH P S +S+ + F+ RCL+++ R T EL+ P++ +
Sbjct: 319 DL----IGHSDLTPQISIRLSAEAQDFLMRCLVKEPGSRWTIGELVDHPFLCSDEEFSHN 374
Query: 1540 G 1540
G
Sbjct: 375 G 375
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 119 bits (298), Expect = 4e-26
Identities = 86/287 (29%), Positives = 143/287 (48%), Gaps = 25/287 (8%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQ------DAKSMKQIFP-SLKEEMRV 1311
W+ +G GS G V A + TG AVK I + + + P +++ E+ +
Sbjct: 21 WKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVI 80
Query: 1312 MEILNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLL-EHGRIEDEMVTQVYTLQLLEG 1370
M++L+HPN++ Y V + + + +E+ E L +LL +HG + + + Q++ G
Sbjct: 81 MKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFR-QIIIG 139
Query: 1371 LACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDM 1430
++ H G+VHRD+KPEN+LLD IK DFG A L DA+ T
Sbjct: 140 ISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAAL---------QTDADLLETS---- 186
Query: 1431 IGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLD-NEWAIMYHVAAGH 1489
G+P Y APE V+G + F S D+WS G ++ ++TGR P+ + N ++ V G
Sbjct: 187 CGSPHYAAPEIVSGLPYEGFAS-DVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQ 245
Query: 1490 LPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNI 1536
+ P +EIS + I + L+ D +R ++L P + + + I
Sbjct: 246 F-EMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTI 291
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 119 bits (298), Expect = 4e-26
Identities = 82/271 (30%), Positives = 128/271 (46%), Gaps = 20/271 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G G FG VY A TG I+A+K + + K I ++ E+ + L H NI++ Y
Sbjct: 124 LGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSK-IEKQVRREIEIQSNLRHKNILRLY 182
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G ++ + +EF L L + E V Y Q+ L+ LH+ V+HRDI
Sbjct: 183 GHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHVIHRDI 242
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
KPENILL +G IK DFG + + +N ++T + GT Y+ PE V G
Sbjct: 243 KPENILLGIDGEIKLSDFGWS----------VHAPSNRRTT----LCGTLDYLPPEMVEG 288
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+ H + D+WSLG + E + G P+ ++ A +A L S + R
Sbjct: 289 KEHTE--KVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDL---KIPSFVPPDAR 343
Query: 1505 KFISRCLIQDANKRATAMELLLDPWISQIRN 1535
ISR L + KR + +++ PWI + ++
Sbjct: 344 DLISRLLQHNPEKRMSLEQVMRHPWIVKYKD 374
>Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 547
Score = 119 bits (298), Expect = 4e-26
Identities = 83/293 (28%), Positives = 143/293 (48%), Gaps = 29/293 (9%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHP 1318
++ + IGSG+ V +A+ + +A+K I ++ ++ L +E++ M +HP
Sbjct: 65 YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMD---ELLKEIQAMSQCSHP 121
Query: 1319 NIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEH---------GRIEDEMVTQVYTLQLLE 1369
N+V YY V +D++ + M+ G S+ ++++ G +E+ ++ + ++LE
Sbjct: 122 NVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILK-EVLE 180
Query: 1370 GLACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKD 1429
GL LH++G +HRD+K NILL +G ++ DFG + +A G ++ K
Sbjct: 181 GLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDV-------TRNKVRKT 233
Query: 1430 MIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGH 1489
+GTP +MAPE V Q G D+WS G +E+ TG P+ +M
Sbjct: 234 FVGTPCWMAPE-VMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLML-TLQND 291
Query: 1490 LPQFPTKSE-------ISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRN 1535
P T E + RK +S CL +D +KR TA ELL + + +N
Sbjct: 292 PPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKN 344
>CE21879 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 328
Score = 119 bits (298), Expect = 4e-26
Identities = 89/277 (32%), Positives = 145/277 (52%), Gaps = 28/277 (10%)
Query: 1265 IGSGSFGTVYSAVNLDTGDI-LAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQY 1323
IG G+FG V+ A L+ I +A+K+I I A K+ +++E + + + H NIV+
Sbjct: 12 IGKGAFGQVFLAEKLNNPRIKVAMKKINIFGAP--KEFLEQIQQEYYIQKNMKHKNIVKM 69
Query: 1324 YGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEM-VTQV--YTLQLLEGLACLHQSGVV 1380
YG+ + + +F EF G L ++ E+ M V QV Y QL+ GL +H G+V
Sbjct: 70 YGMSMDTEFCYLFQEFVTGGDLFEKID---FENGMPVNQVKGYLKQLMSGLKYIHGCGIV 126
Query: 1381 HRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPE 1440
HRDIKP+N+L++ + +K DFG S R +D +K + IGT +MAPE
Sbjct: 127 HRDIKPDNLLINSSDALKIADFGL--------STRFIVD--DKEILLHERIGTTPFMAPE 176
Query: 1441 TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKS--- 1497
+ H + DIWS G +V ++TG PW + E I+Y + + +K+
Sbjct: 177 LFAKKKH-RGPPVDIWSAGILVFSLLTGNLPW-DEPKESDILY---SQWMNNKTSKNCIW 231
Query: 1498 -EISSAGRKFISRCLIQDANKRATAMELLLDPWISQI 1533
+S+ +F+ + L ++ N+RAT E+ DPW+ +
Sbjct: 232 YGLSTPVVRFLKKLLKENVNERATIEEIESDPWLEDL 268
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related proteins
Length = 821
Score = 119 bits (297), Expect = 5e-26
Identities = 85/281 (30%), Positives = 135/281 (47%), Gaps = 33/281 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G G+F TV A+ TG AVK I + + + E+ V++ LNHP IV+
Sbjct: 204 VGQGAFATVKKAIERTTGKTFAVKIIS---KRKVIGNMDGVTRELEVLQKLNHPRIVRLK 260
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLE-HGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
G + + MEF G L + HG + ++ ++ + Q+L + +H G+ HRD
Sbjct: 261 GFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREI-SRQILTAIKYIHSMGISHRD 319
Query: 1384 IKPENILLDRNG--VIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
+KP+NIL++++ ++K DFG AK + NGS K GT Y+APE
Sbjct: 320 LKPDNILIEQDDPVLVKITDFGLAK-VQGNGSFM------------KTFCGTLAYVAPEV 366
Query: 1442 VTG----------QGHGKFGS-DDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHL 1490
+ G + ++ S D+WS+GC+V ++TG P++ + + + G
Sbjct: 367 IRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQD-QLYKQIGRGSY 425
Query: 1491 PQFPTKS-EISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+ P K IS R FI L D N R+TA + L PWI
Sbjct: 426 HEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWI 466
>SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 496
Score = 119 bits (297), Expect = 5e-26
Identities = 82/272 (30%), Positives = 129/272 (47%), Gaps = 19/272 (6%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQI---FPSLKEEMRVMEILN-HPNI 1320
IG+G+F +V + D I AVK + + A S + E+++ ++ N H NI
Sbjct: 16 IGTGAFASVRLCYD-DNAKIYAVKFVNKKHATSCMNAGVWARRMASEIQLHKLCNGHKNI 74
Query: 1321 VQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVV 1380
+ +Y + + +EF +G L +E DE V Q Y QL+EG++ +H GV
Sbjct: 75 IHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFMHSKGVA 134
Query: 1381 HRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPE 1440
HRD+KPENILLD NG +K DFG A L + G R+ +G+P Y APE
Sbjct: 135 HRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLL----------NSPVGSPPYAAPE 184
Query: 1441 TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWAN-LDNEWAIMYHVAAGHLPQFPTKSEI 1499
+T Q G D+WS G ++ ++ G PW + N + + P + + +
Sbjct: 185 -ITQQYDG--SKVDVWSCGIILFALLLGNTPWDEAISNTGDYLLYKKQCERPSYHPWNLL 241
Query: 1500 SSAGRKFISRCLIQDANKRATAMELLLDPWIS 1531
S I+ L D KR + ++ PW++
Sbjct: 242 SPGAYSIITGMLRSDPFKRYSVKHVVQHPWLT 273
>Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 833
Score = 119 bits (297), Expect = 5e-26
Identities = 79/270 (29%), Positives = 135/270 (49%), Gaps = 18/270 (6%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G G++G V+ A + +GD++A+K +K++ + +L++E+ +++ H NIV Y+
Sbjct: 23 LGGGTYGEVFKARDKVSGDLVALKMVKMEPDDDVS----TLQKEILILKTCRHANIVAYH 78
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G + K+ I MEFC SL + + E+ ++L+GLA LH +HRDI
Sbjct: 79 GSYLWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYVCREVLQGLAYLHSQKKIHRDI 138
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K NIL++ G ++ DFG + I ++R+S IGTP +MAPE
Sbjct: 139 KGANILINDAGEVRLADFGISAQIGATLARRLS------------FIGTPYWMAPEVAAV 186
Query: 1445 QGHGKFGS-DDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHL-PQFPTKSEISSA 1502
G + DIWSLG +E+ + P ++ + +G+ P+ K + S+A
Sbjct: 187 ALKGGYNELCDIWSLGITAIELAELQPPLFDVHPLRVLFLMTKSGYQPPRLKEKGKWSAA 246
Query: 1503 GRKFISRCLIQDANKRATAMELLLDPWISQ 1532
FI L + KR +A ++L +SQ
Sbjct: 247 FHNFIKVTLTKSPKKRPSATKMLSHQLVSQ 276
>At3g46140 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 376
Score = 119 bits (297), Expect = 5e-26
Identities = 93/297 (31%), Positives = 148/297 (49%), Gaps = 48/297 (16%)
Query: 1259 WQKRSFIGSGSFGTVYSAVN--LDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILN 1316
W K F+G GS+G+VY A + T +A+K +I A S L +E R++ L+
Sbjct: 96 WIKSEFLGRGSYGSVYLATSKKAKTKTTMAIKSAEISRASS-------LMDEERILTRLS 148
Query: 1317 HPNIVQYYGVEVHRDKV---------NIFMEFCEGSSLASLLEH--GRIEDEMVTQVYTL 1365
P IV+ YG E+ R++ N+ +E+C G SL L+ G + ++ V ++
Sbjct: 149 SPFIVRCYGHEIAREETLFGGERTNYNLILEYCSGKSLFDLVNDNLGGLSEKDV-KLLAR 207
Query: 1366 QLLEGLACLHQSGVVHRDIKPENILL--------DRNGVIKYVDFGAAKLIAKNGSKRIS 1417
+L GL C+H++ ++H DIKPENI L V K DFG A + K S+
Sbjct: 208 DILYGLDCIHRANIIHCDIKPENIFLTPVENRIRPSGYVAKIGDFGLA--LEKGSSE--- 262
Query: 1418 LDANNKSTGGKDMIGTPMYMAPETVTGQGHGKFG-SDDIWSLGCVVLEMVTGRRPWANLD 1476
K++G + GT YM+PE + HG + D W+ GC VLEM+TG++ W
Sbjct: 263 ---YEKASGHRR--GTTRYMSPELIR---HGIVDYAVDTWAFGCTVLEMLTGQQVWGEHS 314
Query: 1477 NEWAIMYHVAAG---HLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+ ++ + + G ++P P +S + F+SRCL +D R LL P++
Sbjct: 315 DLGSVDWDILIGQSCYIPYIP--DWLSEEAQHFLSRCLKRDPASRWGIGALLNHPFL 369
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 118 bits (296), Expect = 6e-26
Identities = 89/296 (30%), Positives = 140/296 (47%), Gaps = 37/296 (12%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIK-------------IQDAKSMKQIFPSL 1305
W+ +G GS G V A N TG AVK I I + + + +
Sbjct: 19 WKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGI 78
Query: 1306 KEEMRVMEILNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLL-EHGRIEDEMVTQVYT 1364
+ E+ +M++LNHPN+++ Y V + + +E+ E L +LL E G + + + +
Sbjct: 79 EREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFR 138
Query: 1365 LQLLEGLACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKS 1424
Q++ G++ H G+VHRD+KPEN+LLD IK DFG A L
Sbjct: 139 -QIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAAL----------------E 181
Query: 1425 TGGK---DMIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLD-NEWA 1480
T GK G+P Y APE V+G + F S D+WS G ++ ++TGR P+ D N
Sbjct: 182 TEGKLLETSCGSPHYAAPEIVSGIPYQGFAS-DVWSCGVILFALLTGRLPFDEEDGNIRT 240
Query: 1481 IMYHVAAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNI 1536
++ V G + P+ EIS + I + L D +R ++L P + + +I
Sbjct: 241 LLLKVQKGEF-EMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQKYPSI 295
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 118 bits (296), Expect = 6e-26
Identities = 79/277 (28%), Positives = 135/277 (48%), Gaps = 21/277 (7%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
+++ +G G+F VY A N+ TG+ +A+K I Q + I +K E+ VM ++ H
Sbjct: 11 KYELGRLLGQGTFAKVYHARNIKTGESVAIKVIDKQKVAKVGLI-DQIKREISVMRLVRH 69
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
P++V + V + K+ ME+ +G L + G+++ E + + Y QL+ + H
Sbjct: 70 PHVVFLHEVMASKTKIYFAMEYVKGGELFDKVSKGKLK-ENIARKYFQQLIGAIDYCHSR 128
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGG--KDMIGTPM 1435
GV HRD+KPEN+LLD NG +K DFG + L +K G GTP
Sbjct: 129 GVYHRDLKPENLLLDENGDLKISDFGLSAL------------RESKQQDGLLHTTCGTPA 176
Query: 1436 YMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPT 1495
Y+APE + +G+ D+WS G V+ ++ G P+ + N + + G +F
Sbjct: 177 YVAPEVIGKKGYDG-AKADVWSCGVVLYVLLAGFLPF-HEQNLVEMYRKITKG---EFKC 231
Query: 1496 KSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
+ +K +SR L + N R +++ + W +
Sbjct: 232 PNWFPPEVKKLLSRILDPNPNSRIKIEKIMENSWFQK 268
>7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 735
Score = 118 bits (296), Expect = 6e-26
Identities = 88/283 (31%), Positives = 138/283 (48%), Gaps = 31/283 (10%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G+GSFGT Y + TG++ A K + + K +L E+ V+ L HPNIVQYY
Sbjct: 25 MGNGSFGTCYKVRDKSTGELFAWKGMNYDELDEAK--CDALVSEISVLRQLQHPNIVQYY 82
Query: 1325 GVEVHRD--KVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYT----LQLLEGLACLHQS- 1377
V+R+ V I ME C G LA +++ R + + + Y QL L H
Sbjct: 83 HHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVLFQLCRALQVCHNKI 142
Query: 1378 ---GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
++HRDIKP NI LD G K DFG A+++ ++ S S +GTP
Sbjct: 143 PNGTILHRDIKPANIFLDAAGNAKLGDFGLARMLRRDQSFAAS------------FVGTP 190
Query: 1435 MYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFP 1494
YM+PE V G+ + + D+W++GC+V EM R P+ + + +A G + P
Sbjct: 191 HYMSPELVKGRKYDR--KSDVWAVGCLVYEMCALRPPFRGRAFD-QLSEKIAQGEFSRIP 247
Query: 1495 TKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNIA 1537
+ S+ ++ I+ L D +R ++ P + +RNI+
Sbjct: 248 --AIYSTDLQEIIAFMLAVDHEQRPGIEVIIRHPLV--VRNIS 286
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 118 bits (295), Expect = 8e-26
Identities = 89/311 (28%), Positives = 149/311 (47%), Gaps = 57/311 (18%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVK------------------------------ 1288
W+ +G GS G V A N++TG + A+K
Sbjct: 81 WKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNV 140
Query: 1289 ---EIKIQDAKSMKQIFP-SLKEEMRVMEILNHPNIVQYYGVEVHRDKVNIFMEFCEGSS 1344
I ++ + Q P ++ E+ +M++++H N++ + V ++ ++ + +E+ +G
Sbjct: 141 SSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGE 200
Query: 1345 LAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDIKPENILLD-RNGVIKYVDF 1402
L L+ G++ + Y Q++EG++ H + HRD+KPEN+LLD +N IK DF
Sbjct: 201 LFDYLVSKGKLPEREAIH-YFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADF 259
Query: 1403 GAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTGQG-HGKFGSDDIWSLGCV 1461
G A +L+ NK K G+P Y +PE V G+ HG G D+WS G V
Sbjct: 260 GMA-----------ALELPNKLL--KTSCGSPHYASPEIVMGRPYHG--GPSDVWSCGIV 304
Query: 1462 VLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATA 1521
+ ++TG P+ N DN ++ V +G ++ S +SS R IS+ L+ D KR T
Sbjct: 305 LFALLTGHLPF-NDDNIKKLLLKVQSG---KYQMPSNLSSEARDLISKILVIDPEKRITT 360
Query: 1522 MELLLDPWISQ 1532
E+L P I +
Sbjct: 361 QEILKHPLIKK 371
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 118 bits (295), Expect = 8e-26
Identities = 86/308 (27%), Positives = 146/308 (46%), Gaps = 46/308 (14%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKE-IKIQDAKSMKQIFPSLKEEMRVMEILN 1316
+++K IG GS+G V+ N DTG I+A+K+ ++ +D +K+I E+R+++ L
Sbjct: 4 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKI---ALREIRMLKQLK 60
Query: 1317 HPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQ 1376
HPN+V V + ++++ E+C+ + L L + R E + + T Q L+ + H+
Sbjct: 61 HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHK 120
Query: 1377 SGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
+HRD+KPENIL+ ++ VIK DFG A+L+ S D + T Y
Sbjct: 121 HNCIHRDVKPENILITKHSVIKLCDFGFARLL------------TGPSDYYTDYVATRWY 168
Query: 1437 MAPETVTGQGHGKFGSD-DIWSLGCVVLEMVTGRRPW---ANLDNEWAI---MYHVAAGH 1489
+PE + G ++G D+W++GCV E+++G W +++D + I + + H
Sbjct: 169 RSPELLVGD--TQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRH 226
Query: 1490 LPQFPTKS---------------------EISSAGRKFISRCLIQDANKRATAMELLLDP 1528
F T IS + CL D +R T +LL P
Sbjct: 227 QQVFSTNQYFSGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTERLTCEQLLHHP 286
Query: 1529 WISQIRNI 1536
+ IR I
Sbjct: 287 YFENIREI 294
>Hs13376582 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 168
Score = 118 bits (295), Expect = 8e-26
Identities = 68/175 (38%), Positives = 95/175 (53%), Gaps = 9/175 (5%)
Query: 1337 MEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDIKPENILLDRNGV 1396
MEF G S++S++ EMV YT Q+L+G+A LH++ VVHRDIK N++L G+
Sbjct: 1 MEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGI 60
Query: 1397 IKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTGQGHGKFGSDDIW 1456
IK +DFG A+ +A G D K M GTP +M PE + G+G+ DIW
Sbjct: 61 IKLIDFGCARRLAWAGLNGTHSDML------KSMHGTPYWMVPEVINESGYGR--KSDIW 112
Query: 1457 SLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGRKFISRCL 1511
S+GC V EM TG+ P A++D A M+++ A P S F+ CL
Sbjct: 113 SIGCTVFEMATGKPPLASMD-RMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCL 166
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 118 bits (295), Expect = 8e-26
Identities = 80/266 (30%), Positives = 129/266 (48%), Gaps = 20/266 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G+F V A N +TG+ +A+K + K + +K E+ +M+++ HP +V+ Y
Sbjct: 15 IGEGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKMV-DQIKREISIMKLVRHPCVVRLY 73
Query: 1325 GVEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
V R K+ I +E+ G L ++ +GR+ E + Y QL++G+ H GV HRD
Sbjct: 74 EVLASRTKIYIILEYITGGELFDKIVRNGRLS-ESEARKYFHQLIDGVDYCHSKGVYHRD 132
Query: 1384 IKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVT 1443
+KPEN+LLD G +K DFG + L T K GTP Y+APE ++
Sbjct: 133 LKPENLLLDSQGNLKISDFGLSAL------------PEQGVTILKTTCGTPNYVAPEVLS 180
Query: 1444 GQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAG 1503
+G+ DIWS G ++ ++ G P+ +D + + +F S +
Sbjct: 181 HKGYNG-AVADIWSCGVILYVLMAGYLPFDEMD----LPTLYSKIDKAEFSCPSYFALGA 235
Query: 1504 RKFISRCLIQDANKRATAMELLLDPW 1529
+ I+R L + R T E+ D W
Sbjct: 236 KSLINRILDPNPETRITIAEIRKDEW 261
>ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 488
Score = 117 bits (294), Expect = 1e-25
Identities = 87/311 (27%), Positives = 159/311 (50%), Gaps = 35/311 (11%)
Query: 1224 KVKRHYSVGKVIDDTDNQXXXXXXXXXXXXXXXXRWQKRSFIGSGSFGTVYSAVNLDTGD 1283
KV+ + +G VI D + ++ + +G G++ Y A +++G+
Sbjct: 20 KVELYMEIGTVITDLEYHT---------------KYMLKKLLGRGAYAQCYLA-EIESGE 63
Query: 1284 ILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYYGVEVHRDKVNIFMEFCEGS 1343
A+K ++++D KS K + L+ E+ + L++PN+V+ Y + V + +E CE
Sbjct: 64 QYAMKVVRLKDIKSRK-VHEKLESEIAIHSKLDNPNVVKMYRSFRSSEYVFMVLELCERG 122
Query: 1344 SLASLLE-HGRIEDEMVTQVYTLQLLEGLACLHQS-GVVHRDIKPENILLDRNGVIKYVD 1401
+L +LL+ +G++++ V + + Q +EGL LH S VVHRD+K N+ LD +K D
Sbjct: 123 ALDALLKRNGKLKERHVAR-FVKQTVEGLIYLHNSVSVVHRDLKLGNLFLDSKFNVKIGD 181
Query: 1402 FGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTGQGHGKFGSDDIWSLGCV 1461
FG + +I K+G K+++ M GTP Y+APE + G+ G DIWSLG +
Sbjct: 182 FGLSAVI-KDGEKKVT------------MCGTPNYIAPEVLFGKASGHSFEADIWSLGVI 228
Query: 1462 VLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATA 1521
+ ++ G P+ + E +Y + + FP ++SS I++ L + +R T
Sbjct: 229 IYTLLVGVPPFQKKNVE--DIYKMIKLNNYIFPENCDLSSEAIDLITQILNTNPLERPTL 286
Query: 1522 MELLLDPWISQ 1532
+L ++S+
Sbjct: 287 EHILSHKFLSK 297
>At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 354
Score = 117 bits (294), Expect = 1e-25
Identities = 80/268 (29%), Positives = 136/268 (49%), Gaps = 25/268 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GS G V + T A+K I++ +S + ++ +E+R+ P +V Y
Sbjct: 74 IGKGSSGNVQLVKHKLTQQFFALKVIQLNTEESTCR---AISQELRINLSSQCPYLVSCY 130
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEH-GRIEDEMVTQVYTLQLLEGLACLH-QSGVVHR 1382
H V+I +EF +G SLA LL+ G++ + M++ + ++L GL +H + ++HR
Sbjct: 131 QSFYHNGLVSIILEFMDGGSLADLLKKVGKVPENMLSAICK-RVLRGLCYIHHERRIIHR 189
Query: 1383 DIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
D+KP N+L++ G +K DFG +K++ S +GT YM+PE +
Sbjct: 190 DLKPSNLLINHRGEVKITDFGVSKILTSTSSL------------ANSFVGTYPYMSPERI 237
Query: 1443 TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNE--WAIMYHVA---AGHLPQFPTKS 1497
+G + DIWSLG V+LE TG+ P+ +++ W+ +Y + + P +
Sbjct: 238 SGSLYS--NKSDIWSLGLVLLECATGKFPYTPPEHKKGWSSVYELVDAIVENPPPCAPSN 295
Query: 1498 EISSAGRKFISRCLIQDANKRATAMELL 1525
S FIS+C+ +D R +A ELL
Sbjct: 296 LFSPEFCSFISQCVQKDPRDRKSAKELL 323
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 117 bits (294), Expect = 1e-25
Identities = 77/270 (28%), Positives = 133/270 (48%), Gaps = 17/270 (6%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
I G+FG V A TGD+ A+K ++ D K S+ E ++ +P +V+++
Sbjct: 834 ISRGAFGHVILARKNTTGDLFAIKVLRKADM-IRKNAVESILAERDILINARNPFVVRFF 892
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ + + ME+ G S+L DE +VY +++ L LH GVVHRD+
Sbjct: 893 YSFTCSENLYLVMEYLNGGDFYSMLRKIGCLDEANARVYIAEVVLALEYLHSEGVVHRDL 952
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKST-------------GGKDMI 1431
KP+N+L+ +G +K DFG +K+ N + +S ++ ++ + +
Sbjct: 953 KPDNLLIAHDGHVKLTDFGLSKVGLINNTDDLSGPVSSATSLLVEEKPKLPTLDHKRSAV 1012
Query: 1432 GTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLP 1491
GTP Y+APE + G GHG + D WS+G ++ E + G P+ N D+ I ++ ++
Sbjct: 1013 GTPDYLAPEILLGTGHG--ATADWWSVGIILYEFLVGIPPF-NADHPQQIFDNILNRNIQ 1069
Query: 1492 QFPTKSEISSAGRKFISRCLIQDANKRATA 1521
P ++S R I R L +D ++R A
Sbjct: 1070 WPPVPEDMSHEARDLIDRLLTEDPHQRLGA 1099
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 117 bits (294), Expect = 1e-25
Identities = 79/276 (28%), Positives = 139/276 (49%), Gaps = 19/276 (6%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQ-IFPSLKEEMRVMEILN 1316
+++ +G G+F VY A N+ +GD +A+K I + K MK + +K E+ ++ +
Sbjct: 73 KYELGKLLGHGTFAKVYLAQNIKSGDKVAIKVIDKE--KIMKSGLVAHIKREISILRRVR 130
Query: 1317 HPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQ 1376
HP IV + V + K+ ME+ G L + + GR+ +E + Y QL+ ++ H
Sbjct: 131 HPYIVHLFEVMATKSKIYFVMEYVGGGELFNTVAKGRLPEETARR-YFQQLISSVSFCHG 189
Query: 1377 SGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
GV HRD+KPEN+LLD G +K DFG + + ++++ D + GTP Y
Sbjct: 190 RGVYHRDLKPENLLLDNKGNLKVSDFGLSAV-----AEQLRQDGLCHT-----FCGTPAY 239
Query: 1437 MAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTK 1496
+APE +T +G+ D+WS G ++ ++ G P+ D +MY + +F
Sbjct: 240 IAPEVLTRKGYDA-AKADVWSCGVILFVLMAGHIPF--YDKNIMVMYKKI--YKGEFRCP 294
Query: 1497 SEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
SS + ++R L + + R T E++ + W +
Sbjct: 295 RWFSSDLVRLLTRLLDTNPDTRITIPEIMKNRWFKK 330
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 117 bits (293), Expect = 1e-25
Identities = 71/216 (32%), Positives = 118/216 (53%), Gaps = 15/216 (6%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQ-IFPSLKEEMRVMEILN 1316
+++ +G G+F VY A N +G+ +A+K I + K +K + +K E+ ++ +
Sbjct: 27 KYEMGRLLGHGTFAKVYLARNAQSGESVAIKVIDKE--KVLKSGLIAHIKREISILRRVR 84
Query: 1317 HPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQ 1376
HPNIVQ + V + K+ ME+ +G L + + GR+++EM + Y QL+ ++ H
Sbjct: 85 HPNIVQLFEVMATKSKIYFVMEYVKGGELFNKVAKGRLKEEMARK-YFQQLISAVSFCHF 143
Query: 1377 SGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
GV HRD+KPEN+LLD NG +K DFG + + S +I D + GTP Y
Sbjct: 144 RGVYHRDLKPENLLLDENGNLKVSDFGLSAV-----SDQIRQDGLFHT-----FCGTPAY 193
Query: 1437 MAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW 1472
+APE + +G+ DIWS G ++ ++ G P+
Sbjct: 194 VAPEVLARKGYDG-AKVDIWSCGVILFVLMAGFLPF 228
>At1g18350 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 307
Score = 117 bits (293), Expect = 1e-25
Identities = 87/281 (30%), Positives = 146/281 (50%), Gaps = 29/281 (10%)
Query: 1260 QKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPN 1319
+K +G GS G VY + TG+I A+K + + + + L EM ++ + P
Sbjct: 46 EKLHVLGRGSSGIVYKVHHKTTGEIYALKSVNGDMSPAFTR---QLAREMEILRRTDSPY 102
Query: 1320 IVQYYGV--EVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
+V+ G+ + +V+I ME+ +G +L SL G + ++ + ++ Q+L+GL+ LH
Sbjct: 103 VVRCQGIFEKPIVGEVSILMEYMDGGNLESL--RGAVTEKQLAG-FSRQILKGLSYLHSL 159
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
+VHRDIKP N+LL+ +K DFG +K+I + SLD N +GT YM
Sbjct: 160 KIVHRDIKPANLLLNSRNEVKIADFGVSKIITR------SLDYCN------SYVGTCAYM 207
Query: 1438 APE---TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDN--EWA-IMYHVAAGHLP 1491
+PE + G+ + + DIWS G ++LE+ G P +WA +M V G P
Sbjct: 208 SPERFDSAAGENSDVY-AGDIWSFGVMILELFVGHFPLLPQGQRPDWATLMCVVCFGEPP 266
Query: 1492 QFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
+ P S R F+ CL +++++R TA +LL P++ +
Sbjct: 267 RAP--EGCSDEFRSFVDCCLRKESSERWTASQLLGHPFLRE 305
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 117 bits (293), Expect = 1e-25
Identities = 80/269 (29%), Positives = 132/269 (48%), Gaps = 18/269 (6%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GSF V A N TGD A+K + + K + LK E+ M+++ HPN+V+
Sbjct: 25 LGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRHKMV-EQLKREISTMKLIKHPNVVEII 83
Query: 1325 GVEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
V + K+ I +E G L + + GR++++ + Y QL+ + H GV HRD
Sbjct: 84 EVMASKTKIYIVLELVNGGELFDKIAQQGRLKEDEARR-YFQQLINAVDYCHSRGVYHRD 142
Query: 1384 IKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVT 1443
+KPEN++LD NGV+K DFG + S+++ D + GTP Y+APE ++
Sbjct: 143 LKPENLILDANGVLKVSDFGLSAF-----SRQVREDGLLHTA-----CGTPNYVAPEVLS 192
Query: 1444 GQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAG 1503
+G+ + D+WS G ++ ++ G P+ +E +M +F S
Sbjct: 193 DKGYDG-AAADVWSCGVILFVLMAGYLPF----DEPNLMTLYKRICKAEFSCPPWFSQGA 247
Query: 1504 RKFISRCLIQDANKRATAMELLLDPWISQ 1532
++ I R L + R + ELL D W +
Sbjct: 248 KRVIKRILEPNPITRISIAELLEDEWFKK 276
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 117 bits (292), Expect = 2e-25
Identities = 84/284 (29%), Positives = 146/284 (50%), Gaps = 19/284 (6%)
Query: 1265 IGSGSFGTVYSAVNLDTGD-ILAVKEI-KIQDAKSMKQIFPSL-KEEMRVMEILNHPNIV 1321
+G GS+ TV+ A++ + + I A+K K K K + ++ K M ++ +H I+
Sbjct: 17 LGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGII 76
Query: 1322 QYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVH 1381
+ Y + + ++F G L SLL +++ T+ +T QL++ L +H G++H
Sbjct: 77 KLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIH 136
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKD------MIGTPM 1435
RD+KPEN+LLDR+G + DFGAA I + S S N+ S G KD +GT
Sbjct: 137 RDLKPENVLLDRDGRLMITDFGAAATIDPSLSGD-SAKFNSDSNGSKDNQNCASFVGTAE 195
Query: 1436 YMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFP- 1494
Y++PE + G +GS DIW+LGC++ + V G+ P+ +NE + A P P
Sbjct: 196 YVSPELLLYNQCG-YGS-DIWALGCMIYQFVQGQPPFRG-ENELKTFEKIVALDYPWGPN 252
Query: 1495 -----TKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQI 1533
+ S I+ + + L+ + N+R + ++ P+ S++
Sbjct: 253 NRINNSTSPINPLVINLVQKILVIEVNERISLEQIKRHPYFSKV 296
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 117 bits (292), Expect = 2e-25
Identities = 83/272 (30%), Positives = 140/272 (50%), Gaps = 24/272 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEI---KIQDAKSMKQIFPSLKEEMRVMEILNHPNIV 1321
IG G+F V A N +TG+ +A+K + K+ K +QI + E+ M+++ HPN+V
Sbjct: 20 IGEGTFAKVKFARNSETGEPVALKILDKEKVLKHKMAEQI----RREIATMKLIKHPNVV 75
Query: 1322 QYYGVEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVV 1380
Q Y V + K+ I +E+ G L ++ GR++++ + Y QL+ + H GV
Sbjct: 76 QLYEVMASKTKIFIILEYVTGGELFDKIVNDGRMKEDEARR-YFQQLIHAVDYCHSRGVY 134
Query: 1381 HRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPE 1440
HRD+KPEN+LLD G +K DFG + L S+++ D ++ GTP Y+APE
Sbjct: 135 HRDLKPENLLLDSYGNLKISDFGLSAL-----SQQVRDDGLLHTS-----CGTPNYVAPE 184
Query: 1441 TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEIS 1500
+ +G+ + D+WS G V+ ++ G P+ + N + +++G +F +S
Sbjct: 185 VLNDRGYDG-ATADMWSCGVVLYVLLAGYLPFDD-SNLMNLYKKISSG---EFNCPPWLS 239
Query: 1501 SAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
K I+R L + R T E+ D W +
Sbjct: 240 LGAMKLITRILDPNPMTRVTPQEVFEDEWFKK 271
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 116 bits (291), Expect = 2e-25
Identities = 78/260 (30%), Positives = 124/260 (47%), Gaps = 17/260 (6%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GSF TV A L T A+K ++ + ++ P + E VM L+HP V+ Y
Sbjct: 88 LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKV-PYVTRERDVMSRLDHPFFVKLY 146
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+K+ + + + L + DE T+ YT +++ L LH G++HRD+
Sbjct: 147 FTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDL 206
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
KPENILL+ + I+ DFG AK+ L +K +GT Y++PE +T
Sbjct: 207 KPENILLNEDMHIQITDFGTAKV----------LSPESKQARANSFVGTAQYVSPELLTE 256
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+ K S D+W+LGC++ ++V G P+ NE+ I + FP K R
Sbjct: 257 KSACK--SSDLWALGCIIYQLVAGLPPF-RAGNEYLIFQKIIKLEY-DFPEK--FFPKAR 310
Query: 1505 KFISRCLIQDANKRATAMEL 1524
+ + L+ DA KR E+
Sbjct: 311 DLVEKLLVLDATKRLGCEEM 330
>CE01405 [T] KOG0577 Serine/threonine protein kinase
Length = 982
Score = 116 bits (291), Expect = 2e-25
Identities = 86/285 (30%), Positives = 134/285 (46%), Gaps = 28/285 (9%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
R+Q IG GSFG VY A + +A+K++ +++++ LKE + + + H
Sbjct: 29 RYQDLREIGHGSFGAVYFAYDKKNEQTVAIKKMNFSGKQAVEKWNDILKE-VSFLNTVVH 87
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSS--LASLLEHGRIEDEMVTQVYTLQLLEGLACLH 1375
P+IV Y + + ME+C GS+ + +L G E E+ Q L+ L LH
Sbjct: 88 PHIVDYKACFLKDTTCWLVMEYCIGSAADIVDVLRKGMREVEIAA--ICSQTLDALRYLH 145
Query: 1376 QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
+HRDIK NILL + ++K DFG+A L+ + IGTP
Sbjct: 146 SLKRIHRDIKAGNILLSDHAIVKLADFGSASLV----------------DPAQTFIGTPF 189
Query: 1436 YMAPETVTGQGHGKF-GSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQF- 1493
+MAPE + G + DIWSLG +E+ R P ++ N + +YH+A P
Sbjct: 190 FMAPEVILAMDEGHYTDRADIWSLGITCIELAERRPPLFSM-NAMSALYHIAQNDPPTLS 248
Query: 1494 ----PTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIR 1534
+ E S +FI +CL + A +R +A E P+I + R
Sbjct: 249 PIDTSEQPEWSLEFVQFIDKCLRKPAEERMSAEECFRHPFIQRSR 293
>At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 561
Score = 116 bits (291), Expect = 2e-25
Identities = 76/273 (27%), Positives = 129/273 (46%), Gaps = 16/273 (5%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G TV+ A+ + ++A IK+ D + ++ E++ M ++NHPN++Q +
Sbjct: 22 IGDGVSATVHRALCIPLNVVVA---IKVLDLEKCNNDLDGIRREVQTMSLINHPNVLQAH 78
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIE--DEMVTQVYTLQLLEGLACLHQSGVVHR 1382
++ + M + G S +++ + +E V + L+ L LH G +HR
Sbjct: 79 CSFTTGHQLWVVMPYMAGGSCLHIIKSSYPDGFEEPVIATLLRETLKALVYLHAHGHIHR 138
Query: 1383 DIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
D+K NILLD NG +K DFG + + G ++ S + +GTP +MAPE V
Sbjct: 139 DVKAGNILLDSNGAVKLADFGVSACMFDTGDRQRSRNT---------FVGTPCWMAPE-V 188
Query: 1443 TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVA-AGHLPQFPTKSEISS 1501
Q HG D+WS G LE+ G P++ ++ + A + S
Sbjct: 189 MQQLHGYDFKADVWSFGITALELAHGHAPFSKYPPMKVLLMTLQNAPPGLDYERDKRFSK 248
Query: 1502 AGRKFISRCLIQDANKRATAMELLLDPWISQIR 1534
A ++ + CL++D KR T+ +LL P+ R
Sbjct: 249 AFKEMVGTCLVKDPKKRPTSEKLLKHPFFKHAR 281
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 116 bits (290), Expect = 3e-25
Identities = 84/273 (30%), Positives = 136/273 (49%), Gaps = 23/273 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG+G F V A ++ TG+++A IKI D ++ P +K E+ ++ L H +I Q Y
Sbjct: 17 IGTGGFAKVKLACHILTGEMVA---IKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLY 73
Query: 1325 GVEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
V +K+ + +E+C G L ++ R+ +E T+V Q++ +A +H G HRD
Sbjct: 74 HVLETANKIFMVLEYCPGGELFDYIISQDRLSEEE-TRVVFRQIVSAVAYVHSQGYAHRD 132
Query: 1384 IKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVT 1443
+KPEN+L D +K +DFG L AK NK + G+ Y APE +
Sbjct: 133 LKPENLLFDEYHKLKLIDFG---LCAK--------PKGNKDYHLQTCCGSLAYAAPELI- 180
Query: 1444 GQGHGKFGSD-DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSA 1502
QG GS+ D+WS+G ++ ++ G P+ + DN A+ + G ++ +S +
Sbjct: 181 -QGKSYLGSEADVWSMGILLYVLMCGFLPFDD-DNVMALYKKIMRG---KYDVPKWLSPS 235
Query: 1503 GRKFISRCLIQDANKRATAMELLLDPWISQIRN 1535
+ + L D KR + LL PWI Q N
Sbjct: 236 SILLLQQMLQVDPKKRISMKNLLNHPWIMQDYN 268
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 116 bits (290), Expect = 3e-25
Identities = 67/210 (31%), Positives = 112/210 (52%), Gaps = 14/210 (6%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQ-IFPSLKEEMRVMEILN 1316
R++K F+G G F TVY A + +T I+A+K+IK+ K I + E+++++ L+
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
Query: 1317 HPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQ 1376
HPNI+ H+ +++ +F E + ++ + + Y L L+GL LHQ
Sbjct: 71 HPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQ 130
Query: 1377 SGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
++HRD+KP N+LLD NGV+K DFG AK S + N++ + T Y
Sbjct: 131 HWILHRDLKPNNLLLDENGVLKLADFGLAK----------SFGSPNRAY--THQVVTRWY 178
Query: 1437 MAPETVTGQGHGKFGSDDIWSLGCVVLEMV 1466
APE + G G D+W++GC++ E++
Sbjct: 179 RAPELLFGARMYGVGV-DMWAVGCILAELL 207
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 115 bits (289), Expect = 4e-25
Identities = 71/210 (33%), Positives = 110/210 (51%), Gaps = 18/210 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G+GSFG V+ + G A+K +K +KQ+ +E R++ I++HP I++ +
Sbjct: 94 LGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQV-EHTNDERRMLSIVSHPFIIRMW 152
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G +V + M++ EG L SLL + V + Y ++ L LH +++RD+
Sbjct: 153 GTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDL 212
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
KPENILLD+NG IK DFG AK + D + GTP Y+APE V+
Sbjct: 213 KPENILLDKNGHIKITDFGFAKYVP---------DVT------YTLCGTPDYIAPEVVST 257
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWAN 1474
+ + K S D WS G ++ EM+ G P+ N
Sbjct: 258 KPYNK--SVDWWSFGVLIYEMLAGYTPFYN 285
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 115 bits (289), Expect = 4e-25
Identities = 74/268 (27%), Positives = 127/268 (46%), Gaps = 13/268 (4%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GSF V +++ TG+ +A+K I + AK + +L+ E ++ +++ HPNI Q
Sbjct: 68 LGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLL 127
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ + + ME C G +L + + +E + Y QL+ + LH++GVVHRD+
Sbjct: 128 DILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHRDL 187
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K EN+LLD + IK +DFG + G S G+P Y APE +
Sbjct: 188 KIENLLLDEDNNIKLIDFGLSNCAGILG----------YSDPFSTQCGSPAYAAPELLAR 237
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+ +G D+WS+G + M+TG P+ +Y P +++S+
Sbjct: 238 KKYGP--KIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDK-EMNPLPTQLSTGAI 294
Query: 1505 KFISRCLIQDANKRATAMELLLDPWISQ 1532
F+ L D KR + L + W+++
Sbjct: 295 SFLRSLLEPDPVKRPNIQQALANRWLNE 322
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 115 bits (289), Expect = 4e-25
Identities = 85/300 (28%), Positives = 131/300 (43%), Gaps = 25/300 (8%)
Query: 1238 TDNQXXXXXXXXXXXXXXXXRWQKRSF-----IGSGSFGTVYSAVNLDTGDILAVKEIKI 1292
T+ Q RW F +G G FG VY A + ++A+K +
Sbjct: 5 TETQHQEKEASDASAAAAQKRWTLSDFDIGKPLGRGKFGHVYLAREKRSNHVVALK-VLF 63
Query: 1293 QDAKSMKQIFPSLKEEMRVMEILNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHG 1352
+ Q+ L+ E+ + L HPNI++ YG + +V + +E+ L L+
Sbjct: 64 KSQLQQSQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKDLQKC 123
Query: 1353 RIEDEMVTQVYTLQLLEGLACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNG 1412
+ E Y L L H V+HRDIKPEN+L+ G +K DFG
Sbjct: 124 KYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFG--------- 174
Query: 1413 SKRISLDANNKSTGGKDMIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW 1472
S+ N+ + M GT Y+ PE V H S DIWSLG + E + G P+
Sbjct: 175 ---WSVHTFNRR---RTMCGTLDYLPPEMVESVEHD--ASVDIWSLGILCYEFLYGVPPF 226
Query: 1473 ANLDNEWAIMYHVAAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
+ E + Y +FP K IS++ + IS+ L++++++R +LL PWI Q
Sbjct: 227 EAM--EHSDTYRRIVQVDLKFPPKPIISASAKDLISQMLVKESSQRLPLHKLLEHPWIVQ 284
>At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 115 bits (289), Expect = 4e-25
Identities = 67/211 (31%), Positives = 114/211 (53%), Gaps = 20/211 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IGSGSF V+ A + G +A+KEI + + K++ SL E+ ++ +NHPNI++
Sbjct: 18 IGSGSFSVVWEARHRVDGTEVAIKEIAMD--RLNKKLQESLMSEIFILRRINHPNIIRLI 75
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ KV++ +E+C+G L+ ++ I E + + QL GL L + ++HRD+
Sbjct: 76 DMIKSPGKVHLVLEYCKGGDLSVYVQRHGIVPEATAKHFMQQLAAGLQVLRDNNIIHRDL 135
Query: 1385 KPENILLDRN---GVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
KP+N+LL N +K DFG A+ + G + + G+P+YMAPE
Sbjct: 136 KPQNLLLSTNENDADLKIADFGFARSLQPRGL-------------AETLCGSPLYMAPEI 182
Query: 1442 VTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW 1472
+ Q + D+WS+G ++ ++VTGR P+
Sbjct: 183 MQLQKYD--AKADLWSVGAILFQLVTGRTPF 211
>At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 571
Score = 115 bits (289), Expect = 4e-25
Identities = 87/285 (30%), Positives = 137/285 (47%), Gaps = 31/285 (10%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQI-FPSLKEEMRVMEILN 1316
R+ +G G FG Y A + TGD +AVK KI AK I +K E+++++ L
Sbjct: 107 RYTIGKLLGHGQFGYTYVATDKKTGDRVAVK--KIDKAKMTIPIAVEDVKREVKILQALT 164
Query: 1317 -HPNIVQYYGVEVHRDKVNIFMEFCEGSSLAS--LLEHGRIEDEMVTQVYTLQLLEGLAC 1373
H N+V++Y ++ V I ME CEG L L E V Q+L+ A
Sbjct: 165 GHENVVRFYNAFEDKNSVYIVMELCEGGELLDRILARKDSRYSERDAAVVVRQMLKVAAE 224
Query: 1374 LHQSGVVHRDIKPENILL---DRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDM 1430
H G+VHRD+KPEN L + + +K DFG + I K G K D+
Sbjct: 225 CHLRGLVHRDMKPENFLFKSTEEDSPLKATDFGLSDFI-KPGKK------------FHDI 271
Query: 1431 IGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRP-WANLDNEWAIMYHVAAGH 1489
+G+ Y+APE + + + D+WS+G + ++ GRRP W ++ ++ +
Sbjct: 272 VGSAYYVAPEVLKRRSGPE---SDVWSIGVISYILLCGRRPFWDKTEDG---IFKEVLKN 325
Query: 1490 LPQFPTK--SEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
P F K IS++ + F+ + L++D R TA + L PW+ +
Sbjct: 326 KPDFRRKPWPTISNSAKDFVKKLLVKDPRARLTAAQALSHPWVRE 370
>CE26076 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 503
Score = 115 bits (288), Expect = 5e-25
Identities = 81/269 (30%), Positives = 129/269 (47%), Gaps = 17/269 (6%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEE---MRVMEILNHPNIV 1321
+G G+FG V VN ++ A + KI A K ++++E + + + H N++
Sbjct: 30 LGEGAFGEVLLIVNTKNPEVAAAMK-KINIANKSKDFIDNIRKEYLLQKRVSAVGHDNVI 88
Query: 1322 QYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVH 1381
+ G+ +F+E+ +G L +E + Q Y QL+ GL +H + VVH
Sbjct: 89 RMIGMRNDPQFYYLFLEYADGGELFDKIEPDCGMSPVFAQFYFKQLICGLKFIHDNDVVH 148
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
RDIKPEN+LL V+K DFG A L G +R+ LD + GT Y APE
Sbjct: 149 RDIKPENLLLTGTHVLKISDFGMATLYRNKGEERL-LDLS---------CGTIPYAAPEL 198
Query: 1442 VTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANL-DNEWAIMYHVAAGHLPQFPTKSEIS 1500
G+ + + D+WS G V++ M+TG PW D + M ++ L + P K +I
Sbjct: 199 CAGKKY-RGPPVDVWSSGIVLIAMLTGELPWDRASDASQSYMGWISNTSLDERPWK-KID 256
Query: 1501 SAGRKFISRCLIQDANKRATAMELLLDPW 1529
+ + + +KRAT ++ DPW
Sbjct: 257 VRALCMLRKIVTDKTDKRATIEQIQADPW 285
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 115 bits (288), Expect = 5e-25
Identities = 87/268 (32%), Positives = 128/268 (47%), Gaps = 19/268 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQ-IFPSLKEEMRVMEILNHPNIVQY 1323
+GSG+F VY A +L G IK+ K +K + +K E+ VM L HP+IV
Sbjct: 34 LGSGAFAKVYQAEDLQNGGESVA--IKVVQKKRLKDGLTAHVKREISVMRRLRHPHIVLL 91
Query: 1324 YGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
V + K+ ME +G L S + R E +++ Y QL+ + H GV HRD
Sbjct: 92 SEVLATKTKIYFVMELAKGGELFSRVTSNRFT-ESLSRKYFRQLISAVRYCHARGVFHRD 150
Query: 1384 IKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVT 1443
+KPEN+LLD N +K DFG + + ++I D + + GTP Y+APE +
Sbjct: 151 LKPENLLLDENRDLKVSDFGLSAM-----KEQIHPDGMLHT-----LCGTPAYVAPELLL 200
Query: 1444 GQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAG 1503
+G+ DIWS G V+ + G P+ + + IM H Q+ SS
Sbjct: 201 KKGYDG-SKADIWSCGVVLFLLNAGYLPFRDPN----IMGLYRKIHKAQYKLPDWTSSDL 255
Query: 1504 RKFISRCLIQDANKRATAMELLLDPWIS 1531
RK + R L + R T E+L DPW +
Sbjct: 256 RKLLRRLLEPNPELRITVEEILKDPWFN 283
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 115 bits (288), Expect = 5e-25
Identities = 79/268 (29%), Positives = 141/268 (52%), Gaps = 21/268 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GSFG VY TG +A+K I ++ K+ K I SL++E+ ++ L H NI++
Sbjct: 12 VGEGSFGRVYKGRRKYTGQTVAMKFI-MKQGKTDKDIH-SLRQEIEILRKLKHENIIEML 69
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ + + EF +G L +LE + E Q QL++ L LH + ++HRD+
Sbjct: 70 DSFENAREFCVVTEFAQGE-LFEILEDDKCLPEEQVQAIAKQLVKALDYLHSNRIIHRDM 128
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
KP+NIL+ V+K DFG A+ ++ N + + + GTP+YMAPE V
Sbjct: 129 KPQNILIGAGSVVKLCDFGFARAMSTN------------TVVLRSIKGTPLYMAPELVKE 176
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
Q + + + D+WSLG ++ E+ G+ P+ ++ +A++ H+ + ++P E+S+
Sbjct: 177 QPYDR--TVDLWSLGVILYELYVGQPPFYT-NSVYALIRHIVKDPV-KYP--DEMSTYFE 230
Query: 1505 KFISRCLIQDANKRATAMELLLDPWISQ 1532
F+ L ++ + R T L P++ +
Sbjct: 231 SFLKGLLNKEPHSRLTWPALREHPFVKE 258
>7294566 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1252
Score = 115 bits (288), Expect = 5e-25
Identities = 90/284 (31%), Positives = 136/284 (47%), Gaps = 29/284 (10%)
Query: 1262 RSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIV 1321
++ IG G FG V+ V T DI A+K+IK + + Q+ KEE +M I N ++
Sbjct: 116 KTLIGQGYFGNVHLVVERQTNDIYAMKKIK-KSVVTTSQV----KEERDIMSIRNSEWLI 170
Query: 1322 QYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVH 1381
D + + ME+ G L SL+ DE + + Y +L L LH+ G VH
Sbjct: 171 NLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTLHEMGYVH 230
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
RDIKPENIL+DR G IK DFG A + ++G +SL +GTP Y+APE
Sbjct: 231 RDIKPENILIDRFGHIKLADFGNAAALDRDGHV-LSLSP----------VGTPDYIAPEL 279
Query: 1442 VTGQGHGKFG------SDDIWSLGCVVLEMVTGRRPW--ANLDNEWA-IMYHVAAGHLPQ 1492
+ K S D WS+G + E++ P+ N+ ++ I+ H HL +
Sbjct: 280 LQTISTYKLSKSMHDVSCDYWSMGIIGYELICETTPFHEDNVHETYSKILSHCEESHLKE 339
Query: 1493 ---FPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQI 1533
FP ++S R I L+ + +KR + + P+ S+I
Sbjct: 340 LISFPADLKVSVNYRNLI-ESLVTNPSKRLSYERIKNHPFFSEI 382
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 115 bits (287), Expect = 7e-25
Identities = 73/265 (27%), Positives = 128/265 (47%), Gaps = 13/265 (4%)
Query: 1263 SFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQ 1322
S IG G++ TV A ++DT A K + + K++ E+ + ++ N P++V+
Sbjct: 183 SVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVR 242
Query: 1323 YYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHR 1382
+ + +E+ SL++ DE + Y Q+++ + LH +G++HR
Sbjct: 243 LFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHR 302
Query: 1383 DIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
DIKPENILLD IK DFG AKL+ + +S + ST K +GT Y++PE +
Sbjct: 303 DIKPENILLDGEMKIKLTDFGTAKLLNPTNNS-VSKPEYDLSTRSKSFVGTAEYVSPELL 361
Query: 1443 TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAI---MYHVAAGHLPQFPTKSEI 1499
DIW+ GC++ +M+ G+ P+ NE+ + V P FP
Sbjct: 362 NDSFTDY--RCDIWAFGCILFQMIAGKPPF-KATNEYLTFQKVMKVQYAFTPGFPL---- 414
Query: 1500 SSAGRKFISRCLIQDANKRATAMEL 1524
R + + L+++ ++R T ++
Sbjct: 415 --IIRDLVKKILVKNLDRRLTISQI 437
>YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 447
Score = 115 bits (287), Expect = 7e-25
Identities = 86/281 (30%), Positives = 132/281 (46%), Gaps = 31/281 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G+GSFG V A L T + +A+K + + + L EE+ +++ L+HPNIV +
Sbjct: 53 LGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFK 112
Query: 1325 GVEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
+DK I + G L +L G+ + ++ +Q+L + +H VVHRD
Sbjct: 113 DWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEII-VQILGAVEYMHSKNVVHRD 171
Query: 1384 IKPENILL---DRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMI----GTPMY 1436
+KPEN+L N + DFG AK + G +D+I G+ Y
Sbjct: 172 LKPENVLYVDKSENSPLVIADFGIAKQL----------------KGEEDLIYKAAGSLGY 215
Query: 1437 MAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLP---QF 1493
+APE +T GHGK DIWS+G + ++ G P+ ++ M A P
Sbjct: 216 VAPEVLTQDGHGK--PCDIWSIGVITYTLLCGYSPFI-AESVEGFMEECTASRYPVTFHM 272
Query: 1494 PTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIR 1534
P IS ++FI + L + R TA ELL DPWI+ R
Sbjct: 273 PYWDNISIDVKRFILKALRLNPADRPTATELLDDPWITSKR 313
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 115 bits (287), Expect = 7e-25
Identities = 77/271 (28%), Positives = 125/271 (45%), Gaps = 16/271 (5%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHP 1318
+ + F+G G F + + D+G+I A K + KS K L E+++ + ++HP
Sbjct: 82 YHRGHFLGEGGFARCFQ-IKDDSGEIFAAKTVAKASIKSEKTR-KKLLSEIQIHKSMSHP 139
Query: 1319 NIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSG 1378
NIVQ+ V I +E C SL LL+ ++ E + +T Q+ + +H
Sbjct: 140 NIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRR 199
Query: 1379 VVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMA 1438
V+HRD+K NI D N +K DFG A ++A ++ ++ GTP Y+A
Sbjct: 200 VIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTI------------CGTPNYIA 247
Query: 1439 PETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSE 1498
PE + G+ G DIWSLG ++ ++ G+ P+ D +Y FP
Sbjct: 248 PEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVN--TIYERIKCRDFSFPRDKP 305
Query: 1499 ISSAGRKFISRCLIQDANKRATAMELLLDPW 1529
IS G+ I L D +R + E++ W
Sbjct: 306 ISDEGKILIRDILSLDPIERPSLTEIMDYVW 336
>Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 313
Score = 115 bits (287), Expect = 7e-25
Identities = 70/259 (27%), Positives = 131/259 (50%), Gaps = 21/259 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G F VY A L +A+K+++I + K +KE + +++ LNHPNI++Y
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKE-IGLLKQLNHPNIIKYL 109
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQ----VYTLQLLEGLACLHQSGVV 1380
+ +++NI +E + L+ ++++ + + ++ + Y +QL + +H V+
Sbjct: 110 DSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVM 169
Query: 1381 HRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPE 1440
HRDIKP N+ + GV+K D G + ++++T ++GTP YM+PE
Sbjct: 170 HRDIKPANVFITATGVVKLGDLGLGRFF------------SSETTAAHSLVGTPYYMSPE 217
Query: 1441 TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRP-WANLDNEWAIMYHVAAGHLPQFPTKSEI 1499
+ G+ DIWSLGC++ EM + P + + N +++ + P P +
Sbjct: 218 RIHENGYN--FKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGE-HY 274
Query: 1500 SSAGRKFISRCLIQDANKR 1518
S R+ +S C+ D ++R
Sbjct: 275 SEKLRELVSMCICPDPHQR 293
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 114 bits (286), Expect = 9e-25
Identities = 73/230 (31%), Positives = 119/230 (51%), Gaps = 20/230 (8%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKE-IKIQDAKSMKQIFPSLKEEMRVMEILN 1316
+++ +G GS+G V N DTG I+A+K+ ++ D K +K+I E+++++ L
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKI---AMREIKLLKQLR 59
Query: 1317 HPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQ 1376
H N+V V + + + EF + + L L D V Q Y Q++ G+ H
Sbjct: 60 HENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHS 119
Query: 1377 SGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
++HRDIKPENIL+ ++GV+K DFG A+ +A G D + T Y
Sbjct: 120 HNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY------------TDYVATRWY 167
Query: 1437 MAPETVTGQ-GHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHV 1485
APE + G +GK + D+W++GC+V EM G P D++ +YH+
Sbjct: 168 RAPELLVGDVKYGK--AVDVWAIGCLVTEMFMG-EPLFPGDSDIDQLYHI 214
>CE07399 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase MKK3/MKK6
Length = 343
Score = 114 bits (286), Expect = 9e-25
Identities = 85/278 (30%), Positives = 133/278 (47%), Gaps = 24/278 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQ-DAKSMKQIFPSLKEEMRVMEILNHPNIVQY 1323
+G G +G V + +G I+AVK IK + +S KQ+ L + R + P +V++
Sbjct: 56 LGKGGYGIVEKMQHRQSGIIMAVKRIKSSINDQSQKQMLNEL-DACRRSDCC--PQMVRF 112
Query: 1324 YGVEVHRDKVNIFMEFCEGSSLASLLEH----GRIEDEMVTQVYTLQLLEGLACL-HQSG 1378
YG V I ME + +SL H G+ E L ++EGL + Q
Sbjct: 113 YGAMFREGDVWICMEVMD-TSLDKFYRHAYKIGKHIPEPFIGKMALSVIEGLNFMKEQLN 171
Query: 1379 VVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMA 1438
++HRD+KP NILL+R+G +K DFG + + + +K + G YM
Sbjct: 172 LIHRDVKPSNILLNRHGQVKICDFGISGHLTNSMAKTVQA-------------GCKPYMP 218
Query: 1439 PETVTGQGHGKFG-SDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKS 1497
PE + G+ + D+WSLG ++E+ G P+AN + + V P+ P +S
Sbjct: 219 PERIDGETKSAYDVRADVWSLGITIIEIAVGTHPYANWKTPFEQLKQVVKEPPPKLPMES 278
Query: 1498 EISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRN 1535
S + F+ RCL +D N+R ELL P++ Q RN
Sbjct: 279 GFSVDCQYFVKRCLEKDYNERPKYPELLAMPFMEQARN 316
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 114 bits (286), Expect = 9e-25
Identities = 78/275 (28%), Positives = 136/275 (49%), Gaps = 17/275 (6%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
+++ +G G+F VY + TG +A+K + Q + + +++ E+ +M L H
Sbjct: 21 KYEVGKLVGCGAFAKVYHGRSTATGQSVAIKVVSKQRLQK-GGLNGNIQREIAIMHRLRH 79
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
P+IV+ + V + K+ MEF +G L + + GR +++ ++ Y QL+ + H
Sbjct: 80 PSIVRLFEVLATKSKIFFVMEFAKGGELFAKVSKGRFCEDL-SRRYFQQLISAVGYCHSR 138
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
G+ HRD+KPEN+LLD +K DFG + L + +I D + + GTP Y+
Sbjct: 139 GIFHRDLKPENLLLDEKLDLKISDFGLSAL-----TDQIRPDGLLHT-----LCGTPAYV 188
Query: 1438 APETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKS 1497
APE + +G+ DIWS G ++ + G P+ D+ +MY + +F
Sbjct: 189 APEVLAKKGYDG-AKIDIWSCGIILFVLNAGYLPFN--DHNLMVMYRKI--YKGEFRIPK 243
Query: 1498 EISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
S R+ ++R L + R T E++ DPW Q
Sbjct: 244 WTSPDLRRLLTRLLDTNPQTRITIEEIIHDPWFKQ 278
>At3g45790 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 376
Score = 114 bits (286), Expect = 9e-25
Identities = 91/281 (32%), Positives = 144/281 (50%), Gaps = 48/281 (17%)
Query: 1259 WQKRSFIGSGSFGTVYSAVN--LDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILN 1316
W K F+G GS+G+VY A + T +A+K +I A S L +E R++ L+
Sbjct: 96 WIKSEFLGRGSYGSVYLATSKKAKTKTTMAIKSAEISRASS-------LMDEERILTRLS 148
Query: 1317 HPNIVQYYGVEVHRDKV---------NIFMEFCEGSSLASLLEH--GRIEDEMVTQVYTL 1365
P IV+ YG E+ R++ N+ +E+C G SL L+ G + ++ V ++
Sbjct: 149 SPFIVRCYGHEIAREETLFGGERTNYNLILEYCSGKSLFDLVNSNLGGLSEKDV-KLLAR 207
Query: 1366 QLLEGLACLHQSGVVHRDIKPENILL-------DRNG-VIKYVDFGAAKLIAKNGSKRIS 1417
+L GL +H++ ++H DIKPENILL NG V K DFG A + K S+
Sbjct: 208 DILYGLDYIHRANIIHCDIKPENILLAPVENRIRPNGYVAKIGDFGLA--LEKGSSE--- 262
Query: 1418 LDANNKSTGGKDMIGTPMYMAPETVTGQGHGKFG-SDDIWSLGCVVLEMVTGRRPWANLD 1476
K++G + GT YM+PE + HG + D W+ GC VLEM+TG++ W
Sbjct: 263 ---YEKASGHRR--GTTRYMSPELIR---HGIVDYAVDTWAFGCTVLEMLTGQQVWGEHS 314
Query: 1477 NEWAIMYHVAAG---HLPQFPTKSEISSAGRKFISRCLIQD 1514
+ ++ + + G ++P P +S + F+SRCL +D
Sbjct: 315 DLGSVDWDILIGQSCYIPYIP--DWLSEEAQHFLSRCLKRD 353
>SPBC409.07c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 605
Score = 114 bits (285), Expect = 1e-24
Identities = 83/279 (29%), Positives = 135/279 (47%), Gaps = 28/279 (10%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G G++G VY A++ TG +A+KEI++ ++ F + E+ ++ P IV +Y
Sbjct: 326 LGKGNYGVVYKALHQPTGVTMALKEIRLSLEEAT---FNQIIMELDILHKAVSPYIVDFY 382
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS-GVVHRD 1383
G V I ME+ + S+ L G I+DE V +++GL L + ++HRD
Sbjct: 383 GAFFVEGSVFICMEYMDAGSMDKLYAGG-IKDEGVLARTAYAVVQGLKTLKEEHNIIHRD 441
Query: 1384 IKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPE--T 1441
+KP N+L++ NG +K DFG + N ++ K IG YMAPE
Sbjct: 442 VKPTNVLVNSNGQVKLCDFG--------------VSGNLVASISKTNIGCQSYMAPERIR 487
Query: 1442 VTGQGHGKFG---SDDIWSLGCVVLEMVTGRRPW--ANLDNEWAIMYHVAAGHLPQFPTK 1496
V G +G D+WSLG +LEM G P+ + + +A + + G P P
Sbjct: 488 VGGPTNGVLTYTVQADVWSLGLTILEMALGAYPYPPESYTSIFAQLSAICDGDPPSLP-- 545
Query: 1497 SEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRN 1535
S R F+++CL ++ + R EL PW+ + +N
Sbjct: 546 DSFSPEARDFVNKCLNKNPSLRPDYHELANHPWLLKYQN 584
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 114 bits (285), Expect = 1e-24
Identities = 81/269 (30%), Positives = 135/269 (50%), Gaps = 25/269 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG GSFG VY + ++A+K I + +S K++ +L+ E+ +M L HPNIV
Sbjct: 10 IGEGSFGRVYKGRRKYSAQVVALKFIP-KLGRSEKEL-RNLQREIEIMRGLRHPNIVHML 67
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+V + ++ EG L + G++ ++ V Q QL+ L LH ++HRD+
Sbjct: 68 DSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQV-QAIAAQLVSALYYLHSHRILHRDM 126
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
KP+NILL + G IK DFG A+ ++ N S+ GTP+YM+PE V
Sbjct: 127 KPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIK------------GTPLYMSPELVEE 174
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTK--SEISSA 1502
+ + + D+WS+GC++ E+ G P+ +A + + P + S IS
Sbjct: 175 RPYDH--TADLWSVGCILYELAVGTPPF------YATSIFQLVSLILKDPVRWPSTISPC 226
Query: 1503 GRKFISRCLIQDANKRATAMELLLDPWIS 1531
+ F+ L +D +R + +LL P+I+
Sbjct: 227 FKNFLQGLLTKDPRQRLSWPDLLYHPFIA 255
>Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 357
Score = 114 bits (285), Expect = 1e-24
Identities = 79/289 (27%), Positives = 136/289 (46%), Gaps = 33/289 (11%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEIL-NH 1317
W+ IG G++G VY N G + AVK + + + ++ E +++ L NH
Sbjct: 27 WEIIETIGKGTYGKVYKVTNKRDGSLAAVKILD-----PVSDMDEEIEAEYNILQFLPNH 81
Query: 1318 PNIVQYYGVEVHRD-----KVNIFMEFCEGSSLASLLEH-----GRIEDEMVTQVYTLQL 1367
PN+V++YG+ D ++ + +E C G S+ L++ R+++ M++ + L
Sbjct: 82 PNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGAL 141
Query: 1368 LEGLACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGG 1427
L GL LH + ++HRD+K NILL G +K VDFG + + +R
Sbjct: 142 L-GLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRR------------ 188
Query: 1428 KDMIGTPMYMAPETVTGQGHGKFGSD---DIWSLGCVVLEMVTGRRPWANLDNEWAIMYH 1484
+GTP +MAPE + + D D+WSLG +E+ G P ++ + ++
Sbjct: 189 NTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFDM-HPVKTLFK 247
Query: 1485 VAAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQI 1533
+ P + FIS+CLI+D +R + LL P+I +
Sbjct: 248 IPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFIKGV 296
>YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 842
Score = 114 bits (284), Expect = 2e-24
Identities = 86/287 (29%), Positives = 133/287 (45%), Gaps = 46/287 (16%)
Query: 1266 GSGSFGTVYSA--------------VNLD-----TGDILAVKEIKIQDAKSMKQIFPSLK 1306
G G+ G+VY A +N D GD +A+K++ + + I
Sbjct: 553 GQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIV---- 608
Query: 1307 EEMRVMEILNHPNIVQYYGVEVHRDK-VNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTL 1365
E+ VM+ H NIV + + D + + MEF EG SL ++E+ D + +
Sbjct: 609 NEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEP 668
Query: 1366 QLL-------EGLACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISL 1418
Q+ +GL LH ++HRDIK +N+LLD +K DFG + SKR +
Sbjct: 669 QIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRAT- 727
Query: 1419 DANNKSTGGKDMIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNE 1478
M+GTP +MAPE V + + + D+WSLG + +EM+ G P+ N D
Sbjct: 728 -----------MVGTPYWMAPEVVKQREYDE--KIDVWSLGIMTIEMLEGEPPYLNEDPL 774
Query: 1479 WAIMYHVAAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELL 1525
A +Y +A P+ +S ++F+S CL D RA+ ELL
Sbjct: 775 KA-LYLIATNGTPKLKHPESLSLEIKRFLSVCLCVDVRYRASTEELL 820
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 114 bits (284), Expect = 2e-24
Identities = 67/215 (31%), Positives = 111/215 (51%), Gaps = 13/215 (6%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
R++ +G G+F VY + T + +A+K I +D + +K E+ VM I H
Sbjct: 11 RYEVGRLLGQGTFAKVYFGRSNHTNESVAIKMID-KDKVMRVGLSQQIKREISVMRIAKH 69
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
PN+V+ Y V + ++ +E+C+G L + + G++++++ + Y QL+ + H
Sbjct: 70 PNVVELYEVMATKSRIYFVIEYCKGGELFNKVAKGKLKEDVAWK-YFYQLISAVDFCHSR 128
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
GV HRDIKPEN+LLD N +K DFG + L D + GTP Y+
Sbjct: 129 GVYHRDIKPENLLLDDNDNLKVSDFGLSAL----------ADCKRQDGLLHTTCGTPAYV 178
Query: 1438 APETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW 1472
APE + +G+ + DIWS G V+ ++ G P+
Sbjct: 179 APEVINRKGY-EGTKADIWSCGVVLFVLLAGYLPF 212
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 114 bits (284), Expect = 2e-24
Identities = 85/261 (32%), Positives = 136/261 (51%), Gaps = 19/261 (7%)
Query: 1266 GSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPS--LKEEMRVMEILNHPNIVQY 1323
G GS+ V A +TG + A +KI D K + + + +K E V++ L HP I++
Sbjct: 48 GVGSYSKVVRAKKKETGTVYA---LKIMDKKFITKENKTAYVKLERIVLDQLEHPGIIKL 104
Query: 1324 YGVEVHRDKVNIFMEFCEGSSLAS-LLEHGRI-EDEMVTQVYTLQLLEGLACLHQSGVVH 1381
Y + + +E CEG L + GR+ EDE + YT ++++ L +H G++H
Sbjct: 105 YFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDE--ARFYTAEVVDALEYIHSMGLIH 162
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTG-GKDMIGTPMYMAPE 1440
RDIKPEN+LL +G IK DFG+ K + +I++ N S +GT Y+ PE
Sbjct: 163 RDIKPENLLLTSDGHIKIADFGSVKPMQ---DSQITVLPNAASDDKACTFVGTAAYVPPE 219
Query: 1441 TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEIS 1500
V FG +D+W+LGC + +M++G P+ + +EW I + A + +FP + S
Sbjct: 220 -VLNSSPATFG-NDLWALGCTLYQMLSGTSPFKDA-SEWLIFQRIIARDI-KFP--NHFS 273
Query: 1501 SAGRKFISRCLIQDANKRATA 1521
A R I R L + ++R A
Sbjct: 274 EAARDLIDRLLDTEPSRRPGA 294
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 113 bits (283), Expect = 2e-24
Identities = 86/276 (31%), Positives = 142/276 (51%), Gaps = 30/276 (10%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G+GSFG V+ + A+K ++ + MKQI + +E ++ + HP I +
Sbjct: 207 LGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTC-DERYILSRVQHPFITILW 265
Query: 1325 GVEVHRDKVNIFM--EFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHR 1382
G +D N+FM +F EG L SLL E V + Y +++ L LH + +V+R
Sbjct: 266 GT--FQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDYLHHNQIVYR 323
Query: 1383 DIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
D+KPEN+LLDR G +K VDFG AK ++ +N T + GTP Y+APE +
Sbjct: 324 DLKPENLLLDRFGHLKIVDFGFAKRVS----------TSNCCT----LCGTPDYLAPEII 369
Query: 1443 TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSA 1502
+ + + K + D WSLG ++ EM+ G P+ + +N + ++ G + +P S S A
Sbjct: 370 SLKPYNK--AADWWSLGILIFEMLAGYPPFYS-ENPMKLYENILEGKV-NYP--SYFSPA 423
Query: 1503 GRKFISRCLIQD-----ANKRATAMELLLDPWISQI 1533
+S L +D N + +M++++ PW I
Sbjct: 424 SIDLLSHLLQRDITCRYGNLKDGSMDIIMHPWFRDI 459
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 113 bits (283), Expect = 2e-24
Identities = 78/259 (30%), Positives = 123/259 (47%), Gaps = 22/259 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G+FG V A + TG A+K + I+ M+Q + E RV+ L HP IV+ Y
Sbjct: 69 IGKGTFGRVELARDKITGAHYALKVLNIRRVVDMRQT-QHVHNEKRVLLQLKHPFIVKMY 127
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
E + + + MEF G + S L R + + Y +++ L +H G+V+RD+
Sbjct: 128 ASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDL 187
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
KPEN++L + G IK DFG AK + + GTP Y+APE++
Sbjct: 188 KPENLMLSKEGHIKMADFGFAKELRDR---------------TYTICGTPDYLAPESLAR 232
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
GH K D W+LG ++ EM+ G+ P+ + +Y H +FP + A +
Sbjct: 233 TGHNK--GVDWWALGILIYEMMVGKPPFRG--KTTSEIYDAIIEHKLKFPRSFNL--AAK 286
Query: 1505 KFISRCLIQDANKRATAME 1523
+ + L D +R M+
Sbjct: 287 DLVKKLLEVDRTQRIGCMK 305
>CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 294
Score = 113 bits (283), Expect = 2e-24
Identities = 63/212 (29%), Positives = 110/212 (51%), Gaps = 19/212 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G F V+ A +A+K+I++ + K LKE + +++ LNH N+++YY
Sbjct: 29 IGKGQFSEVFRAQCTWVDLHVALKKIQVFEMVDQKARQDCLKE-IDLLKQLNHVNVIRYY 87
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEH----GRIEDEMVTQVYTLQLLEGLACLHQSGVV 1380
+ +++NI +E E ++ +++H GR+ E Y +QL LA +H ++
Sbjct: 88 ASFIDNNQLNIVLELAEAGDMSRMIKHFKKGGRLIPEKTIWKYFVQLARALAHMHSKRIM 147
Query: 1381 HRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPE 1440
HRDIKP N+ + NG++K D G + ++K+T ++GTP YM+PE
Sbjct: 148 HRDIKPANVFITGNGIVKLGDLGLGRFF------------SSKTTAAHSLVGTPYYMSPE 195
Query: 1441 TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW 1472
+ G+ D+WS GC++ EM + P+
Sbjct: 196 RIQESGYN--FKSDLWSTGCLLYEMAALQSPF 225
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 113 bits (283), Expect = 2e-24
Identities = 84/280 (30%), Positives = 126/280 (45%), Gaps = 25/280 (8%)
Query: 1258 RWQKRSF-----IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVM 1312
RW F +G G FG VY A + I+A+K + + Q+ L+ E+ +
Sbjct: 13 RWTTSDFDIGKPLGRGKFGHVYLAREKRSDHIVALK-VLFKAQLQQSQVEHQLRREVEIQ 71
Query: 1313 EILNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLA 1372
L HPNI++ YG + +V + +E+ L L+ + E Y L L
Sbjct: 72 SHLRHPNILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERRAATYVASLARALI 131
Query: 1373 CLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIG 1432
H V+HRDIKPEN+L+ G +K DFG S+ N+ + M G
Sbjct: 132 YCHGKHVIHRDIKPENLLIGAQGELKIADFG------------WSVHTFNRR---RTMCG 176
Query: 1433 TPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQ 1492
T Y+ PE V H S DIWSLG + E + G P+ E + Y +
Sbjct: 177 TLDYLPPEMVESVEHD--ASVDIWSLGILCYEFLYGVPPFE--AREHSETYKRIVQVDLK 232
Query: 1493 FPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
FP K +SS+ + IS+ L++++ +R +LL PWI Q
Sbjct: 233 FPPKPIVSSSAKDLISQMLVKESTQRLALHKLLEHPWIVQ 272
>YDR523c [T] KOG0201 Serine/threonine protein kinase
Length = 490
Score = 113 bits (282), Expect = 3e-24
Identities = 84/277 (30%), Positives = 138/277 (49%), Gaps = 27/277 (9%)
Query: 1262 RSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIV 1321
+S IG G+FG VY AV+ T +I+A+K + ++ + ++ L +E+ + L P I
Sbjct: 21 QSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIEL---LAQEIFFLAELKSPLIT 77
Query: 1322 QYYGVEVHRDKVNIFMEFCEGSSLASLLE----HGRIEDEMVTQVYTLQLLEGLACLHQS 1377
Y + + I ME+C G S + LL+ +G E+++ ++ + L GL LH+
Sbjct: 78 NYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTL--GLKYLHEQ 135
Query: 1378 GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKD-MIGTPMY 1436
+HRDIK NILL+ G++K DFG + I +ST +D +GTP +
Sbjct: 136 RKIHRDIKAANILLNEEGMVKLGDFGVSGHI--------------RSTLKRDTFVGTPYW 181
Query: 1437 MAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTK 1496
MAPE V + G DIWSLG E++ G P + D +M ++ P+ +
Sbjct: 182 MAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYD-PMKVMTNLPKRKPPKL--Q 238
Query: 1497 SEISSAGRKFISRCLIQDANKRATAMELLLDPWISQI 1533
S A + F++ CL++ R +A LL ++ I
Sbjct: 239 GPFSDAAKDFVAGCLVKTPADRPSAYNLLSFEFVKNI 275
>Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 596
Score = 113 bits (282), Expect = 3e-24
Identities = 74/272 (27%), Positives = 131/272 (47%), Gaps = 22/272 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G G FG V + + TG LA K IK Q K + + E+ VM LNH N++Q Y
Sbjct: 291 LGGGKFGAVCTCMEKATGLKLAAKVIKKQTPKDKEMVLL----EIEVMNQLNHRNLIQLY 346
Query: 1325 GVEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
++ +FME+ EG L +++ E+ T V+ Q+ +G+ +H+ V+H D
Sbjct: 347 AAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLD 406
Query: 1384 IKPENIL-LDRNG-VIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
+KPENIL ++ G ++K +DFG A+ N +++ GTP +++PE
Sbjct: 407 LKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVN-------------FGTPEFLSPEV 453
Query: 1442 VTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISS 1501
V D+WS+G + +++G P+ D+ + ++ T +S
Sbjct: 454 VNYDQIS--DKTDMWSMGVITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSD 511
Query: 1502 AGRKFISRCLIQDANKRATAMELLLDPWISQI 1533
+ F+S +++D R A + L PW++ +
Sbjct: 512 EAKDFVSNLIVKDQRARMNAAQCLAHPWLNNL 543
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 113 bits (282), Expect = 3e-24
Identities = 84/270 (31%), Positives = 132/270 (48%), Gaps = 23/270 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+GSG FG V A +L T +A IKI D K + P ++ EM + L+H NI + Y
Sbjct: 17 LGSGGFGKVRLATHLLTNQKVA---IKIIDKKQLGHDLPRVQTEMDALRNLSHQNICRLY 73
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
DK I ME+C G + + +E + + QL+ +A +H G HRD+
Sbjct: 74 HYIETEDKFFIVMEYCSGGEMFDYIVRKERLEESEARHFFRQLVSAIAFVHSQGYAHRDL 133
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
KPEN+LL + +K +DFG L AK RI D +N T G+P Y APE + G
Sbjct: 134 KPENLLLTEDLHLKLIDFG---LCAKTEKGRI--DKHNLDT----CCGSPAYAAPELIQG 184
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMY-HVAAG--HLPQFPTKSEISS 1501
+ K D+WS+G ++ ++ G P+ D+ IMY + +G + P+F +S
Sbjct: 185 LQY-KGNEADVWSMGILLYTLLVGALPFE--DDNMQIMYKKIQSGCFYEPEF-----LSP 236
Query: 1502 AGRKFISRCLIQDANKRATAMELLLDPWIS 1531
++ + L +R + +LL W++
Sbjct: 237 LSKQLLRAMLQVVPERRISVKKLLEHDWLN 266
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 113 bits (282), Expect = 3e-24
Identities = 74/242 (30%), Positives = 129/242 (52%), Gaps = 27/242 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMK-QIFPSLKEEMRVMEILNHPNIVQY 1323
IGSGSF V+ A + +G +AVKEI D K + ++ +L +E+ ++ ++HPNI+++
Sbjct: 16 IGSGSFAVVWLAKHRSSGLEVAVKEI---DKKLLSPKVRDNLLKEISILSTIDHPNIIRF 72
Query: 1324 YGVEVHRDKVNIFMEFCEGSSLASLLE-HGRIEDEMVTQVYTLQLLEGLACLHQSGVVHR 1382
Y D++ + +E+C G LA + HG++ E V + + QL GL L + +HR
Sbjct: 73 YEAIETGDRIFLVLEYCSGGDLAGYINRHGKVP-EAVAKHFMRQLALGLQVLQEKHFIHR 131
Query: 1383 DIKPENILLDRNGV---IKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAP 1439
D+KP+N+LL V +K DFG A+ + + G+P+YMAP
Sbjct: 132 DLKPQNLLLSSKEVTPLLKIGDFGFARSLTPESM-------------AETFCGSPLYMAP 178
Query: 1440 ETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFP--TKS 1497
E + Q + D+WS G ++ ++VTG+ P+ +N + +++ +FP T++
Sbjct: 179 EIIRNQKYD--AKADLWSAGAILFQLVTGKPPFDG-NNHIQLFHNIVRDTELKFPEDTRN 235
Query: 1498 EI 1499
EI
Sbjct: 236 EI 237
>Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase
Length = 330
Score = 113 bits (282), Expect = 3e-24
Identities = 73/272 (26%), Positives = 134/272 (48%), Gaps = 19/272 (6%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G G+FG + ++ KE+ + ++ E+ ++ +L H NI+ YY
Sbjct: 58 LGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKER--RDALNEIVILALLQHDNIIAYY 115
Query: 1325 GVEVHRDKVNIFMEFCEGSSLAS--LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHR 1382
+ + I +E+C G +L L + ++ +E + Y Q++ ++C+H++G++HR
Sbjct: 116 NHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGILHR 175
Query: 1383 DIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
DIK NI L + +IK D+G AK + N++ + + ++GTP YM+PE
Sbjct: 176 DIKTLNIFLTKANLIKLGDYGLAKKL------------NSEYSMAETLVGTPYYMSPELC 223
Query: 1443 TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSA 1502
G + DIW++GCV+ E++T +R + + N + + G S+ S
Sbjct: 224 QGVKYN--FKSDIWAVGCVIFELLTLKRTF-DATNPLNLCVKIVQGIRAMEVDSSQYSLE 280
Query: 1503 GRKFISRCLIQDANKRATAMELLLDPWISQIR 1534
+ + CL QD +R TA ELL P + + R
Sbjct: 281 LIQMVHSCLDQDPEQRPTADELLDRPLLRKRR 312
>YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 655
Score = 112 bits (281), Expect = 4e-24
Identities = 77/260 (29%), Positives = 130/260 (49%), Gaps = 29/260 (11%)
Query: 1282 GDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYYGVEVHRDK-VNIFMEFC 1340
G+ +A+K+I++ + + KQ+ + E+ VM NIV + + D+ + + ME+
Sbjct: 400 GERVAIKQIRLSE-QPKKQL---IMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYM 455
Query: 1341 EGSSLASLL---------EHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDIKPENILL 1391
EG L +L EH +E + +GL LH ++HRDIK +NILL
Sbjct: 456 EGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILL 515
Query: 1392 DRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTGQGHGKFG 1451
+ G++K DFG + + SKR + M+GTP +MAPE V +G+ +
Sbjct: 516 NSQGLVKITDFGFCVELTEKRSKRAT------------MVGTPYWMAPEIVNQKGYDE-- 561
Query: 1452 SDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGRKFISRCL 1511
D+WSLG +++EM+ G P+ N D A +Y +A P+ +S ++F+ CL
Sbjct: 562 KVDVWSLGIMLIEMIEGEPPYLNEDPLKA-LYLIANNGSPKLRHPESVSKQTKQFLDACL 620
Query: 1512 IQDANKRATAMELLLDPWIS 1531
+ RA+ +LL ++S
Sbjct: 621 QVNVESRASVRKLLTFEFLS 640
>YJL128c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 668
Score = 112 bits (281), Expect = 4e-24
Identities = 85/283 (30%), Positives = 134/283 (47%), Gaps = 32/283 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQ-DAKSMKQIFPSLKEEMRVMEILNHPNIVQY 1323
+G G++G V ++ T I+A KE++++ D +QI E+ V+ N P IV +
Sbjct: 366 LGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKFRQILM----ELEVLHKCNSPYIVDF 421
Query: 1324 YGVEVHRDKVNIFMEFCEGSSLASLLEH----GRIEDEMVTQVYTLQLLEGLACL-HQSG 1378
YG V + ME+ +G SL + + G I++ + + ++ GL L Q
Sbjct: 422 YGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANA-VIHGLKELKEQHN 480
Query: 1379 VVHRDIKPENILLDRN-GVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYM 1437
++HRD+KP NIL N G +K DFG + N ++ K IG YM
Sbjct: 481 IIHRDVKPTNILCSANQGTVKLCDFGVS--------------GNLVASLAKTNIGCQSYM 526
Query: 1438 APETVTGQGHGKFG---SDDIWSLGCVVLEMVTGRRPW--ANLDNEWAIMYHVAAGHLPQ 1492
APE + + DIWSLG +LEM GR P+ DN ++ + + G P+
Sbjct: 527 APERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPR 586
Query: 1493 FPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRN 1535
P+ + SS + F+S CL + +R T L PW+ + RN
Sbjct: 587 LPS-DKFSSDAQDFVSLCLQKIPERRPTYAALTEHPWLVKYRN 628
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 112 bits (281), Expect = 4e-24
Identities = 80/266 (30%), Positives = 123/266 (46%), Gaps = 19/266 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQ-IFPSLKEEMRVMEILNHPNIVQY 1323
+G G+F VY ++ T +A+K I K MK + +K E+ VM I HPN+V+
Sbjct: 18 LGQGTFAKVYYGRSILTNQSVAIK--MIDKEKVMKVGLIEQIKREISVMRIARHPNVVEL 75
Query: 1324 YGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
Y V + ++ ME+C+G L + + G++ D+ V Y QL+ + H V HRD
Sbjct: 76 YEVMATKTRIYFVMEYCKGGELFNKVAKGKLRDD-VAWKYFYQLINAVDFCHSREVYHRD 134
Query: 1384 IKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVT 1443
IKPEN+LLD N +K DFG + L D + GTP Y+APE +
Sbjct: 135 IKPENLLLDDNENLKVSDFGLSAL----------ADCKRQDGLLHTTCGTPAYVAPEVIN 184
Query: 1444 GQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAG 1503
+G+ + DIWS G V+ ++ G P+ D+ MY F S +
Sbjct: 185 RKGYDGTKA-DIWSCGVVLFVLLAGYLPFH--DSNLMEMYRKIG--KADFKAPSWFAPEV 239
Query: 1504 RKFISRCLIQDANKRATAMELLLDPW 1529
R+ + + L + R T + W
Sbjct: 240 RRLLCKMLDPNPETRITIARIRESSW 265
>At5g40440 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 520
Score = 112 bits (281), Expect = 4e-24
Identities = 86/271 (31%), Positives = 130/271 (47%), Gaps = 21/271 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IGSG+ V A+++ ILA+K+I I + + +Q+ L E + E H +V ++
Sbjct: 89 IGSGASSVVQRAIHIPNHRILALKKINIFEREKRQQL---LTEIRTLCEAPCHEGLVDFH 145
Query: 1325 GVEVHRD--KVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQ-SGVVH 1381
G D +++I +E+ G SLA +L+ + E V +LL+GL+ LH +VH
Sbjct: 146 GAFYSPDSGQISIALEYMNGGSLADILKVTKKIPEPVLSSLFHKLLQGLSYLHGVRHLVH 205
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
RDIKP N+L++ G K DFG IS N +GT YM+PE
Sbjct: 206 RDIKPANLLINLKGEPKITDFG------------ISAGLENSMAMCATFVGTVTYMSPER 253
Query: 1442 VTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISS 1501
+ + DIWSLG + E TG P+ + +M + P P K E S
Sbjct: 254 IRNDSYSY--PADIWSLGLALFECGTGEFPYIANEGPVNLMLQILDDPSPT-PPKQEFSP 310
Query: 1502 AGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
FI CL +D + R TA +LL P+I++
Sbjct: 311 EFCSFIDACLQKDPDARPTADQLLSHPFITK 341
>7290147 [T] KOG0583 Serine/threonine protein kinase
Length = 291
Score = 112 bits (281), Expect = 4e-24
Identities = 77/218 (35%), Positives = 115/218 (52%), Gaps = 27/218 (12%)
Query: 1265 IGSGSFGTVY----SAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNI 1320
+G G+FG V+ + V + VK I +++ K+ + +KEE+ ++ L HP+I
Sbjct: 14 LGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRNPKTELGL---IKEEVYIISQLRHPHI 70
Query: 1321 VQYYGVEVHRDKVNIFMEFCEGSSLASLLEH-----GRIEDEMVTQVYTLQLLEGLACLH 1375
V++ H VNI ME+ +L +++ G + E + Y ++ GL LH
Sbjct: 71 VEFLRSFSHAGTVNIVMEYVPNGTLRDVIQQLPSGTGGVNQERLMG-YFRDMVVGLEYLH 129
Query: 1376 QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
V+HRDIKPEN+LLD N +K DFG A + A ST + +GTPM
Sbjct: 130 IRCVIHRDIKPENMLLDANDRVKIADFGIANVHA-------------PSTQLQAGMGTPM 176
Query: 1436 YMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWA 1473
YMAPE ++ QG F S D+WSLG V+ E+ GR P+A
Sbjct: 177 YMAPEAMSSQGKVDFKS-DVWSLGLVLYELCLGRSPFA 213
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 112 bits (280), Expect = 5e-24
Identities = 68/211 (32%), Positives = 112/211 (52%), Gaps = 14/211 (6%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHP 1318
++K IG G++G VY A+N TGD++A+K I+++ K I + E+++++ L H
Sbjct: 277 YEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPI--TTVREVKILQRLRHK 334
Query: 1319 NIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSG 1378
NIV+ + V + V + E+ + LL + + Q+ E LA LH G
Sbjct: 335 NIVRLLEIMVEKSSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSKQIFEALAYLHHRG 394
Query: 1379 VVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMA 1438
V+HRDIK NILL+ NG +K+ DFG A+ + ++KS + + T +
Sbjct: 395 VLHRDIKGSNILLNNNGDLKFADFGLAR-----------FNTSSKSANYTNRVITLWFRP 443
Query: 1439 PETVTGQGHGKFGSDDIWSLGCVVLEMVTGR 1469
PE + G+ + DIWS GC+V+E+ TG+
Sbjct: 444 PELLLGE-TAYDTAVDIWSAGCIVMELFTGK 473
>CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1096
Score = 112 bits (280), Expect = 5e-24
Identities = 77/283 (27%), Positives = 138/283 (48%), Gaps = 34/283 (12%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEI-LNHPNIVQY 1323
+G+G++G VY ++ T + A+K + I + + +K E+ +++ +H N+ Y
Sbjct: 27 VGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEE-----DEIKLEINMLKKHSHHRNVATY 81
Query: 1324 YGVEVHR--------DKVNIFMEFCEGSSLASLLEH---GRIEDEMVTQVYTLQLLEGLA 1372
YG + + D++ + MEFC S+ L+++ G +++E + + ++L GL
Sbjct: 82 YGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGGSLKEEWIAYICR-EILRGLY 140
Query: 1373 CLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIG 1432
LHQS V+HRDIK +N+LL + +K VDFG + + K +R IG
Sbjct: 141 HLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRR------------NTFIG 188
Query: 1433 TPMYMAPETVTGQGHGKFGSD---DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGH 1489
TP +MAPE + + D D+WSLG LEM G P ++ + ++ +
Sbjct: 189 TPYWMAPEVIACDESPEATYDSRSDLWSLGITALEMAEGHPPLCDM-HPMRALFLIPRNP 247
Query: 1490 LPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
P+ + + FI L++D ++R LL P+I +
Sbjct: 248 PPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFIKE 290
>CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1082
Score = 112 bits (280), Expect = 5e-24
Identities = 77/283 (27%), Positives = 138/283 (48%), Gaps = 34/283 (12%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEI-LNHPNIVQY 1323
+G+G++G VY ++ T + A+K + I + + +K E+ +++ +H N+ Y
Sbjct: 27 VGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEE-----DEIKLEINMLKKHSHHRNVATY 81
Query: 1324 YGVEVHR--------DKVNIFMEFCEGSSLASLLEH---GRIEDEMVTQVYTLQLLEGLA 1372
YG + + D++ + MEFC S+ L+++ G +++E + + ++L GL
Sbjct: 82 YGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGGSLKEEWIAYICR-EILRGLY 140
Query: 1373 CLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIG 1432
LHQS V+HRDIK +N+LL + +K VDFG + + K +R IG
Sbjct: 141 HLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRR------------NTFIG 188
Query: 1433 TPMYMAPETVTGQGHGKFGSD---DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGH 1489
TP +MAPE + + D D+WSLG LEM G P ++ + ++ +
Sbjct: 189 TPYWMAPEVIACDESPEATYDSRSDLWSLGITALEMAEGHPPLCDM-HPMRALFLIPRNP 247
Query: 1490 LPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
P+ + + FI L++D ++R LL P+I +
Sbjct: 248 PPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFIKE 290
>CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1087
Score = 112 bits (280), Expect = 5e-24
Identities = 77/283 (27%), Positives = 138/283 (48%), Gaps = 34/283 (12%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEI-LNHPNIVQY 1323
+G+G++G VY ++ T + A+K + I + + +K E+ +++ +H N+ Y
Sbjct: 27 VGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEE-----DEIKLEINMLKKHSHHRNVATY 81
Query: 1324 YGVEVHR--------DKVNIFMEFCEGSSLASLLEH---GRIEDEMVTQVYTLQLLEGLA 1372
YG + + D++ + MEFC S+ L+++ G +++E + + ++L GL
Sbjct: 82 YGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGGSLKEEWIAYICR-EILRGLY 140
Query: 1373 CLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIG 1432
LHQS V+HRDIK +N+LL + +K VDFG + + K +R IG
Sbjct: 141 HLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRR------------NTFIG 188
Query: 1433 TPMYMAPETVTGQGHGKFGSD---DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGH 1489
TP +MAPE + + D D+WSLG LEM G P ++ + ++ +
Sbjct: 189 TPYWMAPEVIACDESPEATYDSRSDLWSLGITALEMAEGHPPLCDM-HPMRALFLIPRNP 247
Query: 1490 LPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
P+ + + FI L++D ++R LL P+I +
Sbjct: 248 PPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFIKE 290
>CE23001 [R] KOG0589 Serine/threonine protein kinase
Length = 579
Score = 112 bits (280), Expect = 5e-24
Identities = 71/270 (26%), Positives = 135/270 (49%), Gaps = 20/270 (7%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
R+++ +G G+FG+ + ++ +KEI + D S ++ E+ ++ + H
Sbjct: 170 RYERIRTVGKGAFGSAVLYRRREDSSLVIIKEINMYDLDSSQRRLAL--NEVSLLSRIEH 227
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGR--IEDEMVTQVYTLQLLEGLACLH 1375
PNI+ YY + I ME+ +G +LA +L + +++E + + +Q+ +A LH
Sbjct: 228 PNIIAYYDSFEEEGVLMIEMEYADGGTLAQMLSRTQNLLDEEQIGDMM-IQMCSAVAYLH 286
Query: 1376 QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
++ V+HRD+K N+ L R+ +K DFG +K+ + + G K ++GTP
Sbjct: 287 ENSVLHRDLKTANVFLTRDSFVKIGDFGISKI----------MGTETLAQGAKTVVGTPY 336
Query: 1436 YMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPT 1495
Y++PE +G + + D+W+LGC++ EM ++ + DN A++ + P
Sbjct: 337 YISPEMCSGVSYNE--KSDMWALGCILYEMCCLKKAFEG-DNLPALVNSIMT--CAYTPV 391
Query: 1496 KSEISSAGRKFISRCLIQDANKRATAMELL 1525
K S+ + I L D KR +A + L
Sbjct: 392 KGPYSAEMKMVIRELLQLDPQKRPSAPQAL 421
>CE09360 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 2783
Score = 112 bits (280), Expect = 5e-24
Identities = 82/320 (25%), Positives = 150/320 (46%), Gaps = 24/320 (7%)
Query: 1220 EKVVKVKRHYSVG--KVIDDTDNQXXXXXXXXXXXXXXXXRWQKRSFIGSGSFGTVYSAV 1277
+K VKVK SV +V D++ ++ +G G++GTVY A
Sbjct: 154 KKEVKVKEQESVDYERVAKDSEPSEYKTIDIHRLPNDLQAKYIIHEELGKGAYGTVYRAT 213
Query: 1278 NLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYYGVEVHRDKVNIFM 1337
TG A K ++++ + + E+ +M L+H ++ + +++ +
Sbjct: 214 EKATGKTWAAKMVQVRPGVKKENVI----HEISMMNQLHHEKLLNLHEAFDMGNEMWLIE 269
Query: 1338 EFCEGSSL-ASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDIKPENILL--DRN 1394
EF G L +LE + E + Y Q+L G++ +H++ +VH D+KPENILL +
Sbjct: 270 EFVSGGELFEKILEDDSLMSEEEVRDYMHQILLGVSHMHKNQIVHLDLKPENILLKAKNS 329
Query: 1395 GVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTGQGHGKFGSDD 1454
+K +DFG A+ + S ++ + GTP + APE V Q G S D
Sbjct: 330 NELKIIDFGLARKLDPKKSVKL-------------LFGTPEFCAPEVVNYQPVGL--STD 374
Query: 1455 IWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGRKFISRCLIQD 1514
+W++G + +++G P+ +E + A+ P+ ++S + FI R +I+D
Sbjct: 375 MWTVGVISYVLLSGLSPFLGDSDEDTLANVSASDWDFDDPSWDDVSDLAKDFICRLMIKD 434
Query: 1515 ANKRATAMELLLDPWISQIR 1534
KR + + L PWI++++
Sbjct: 435 KRKRMSVQDALRHPWITKMQ 454
>At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 487
Score = 112 bits (280), Expect = 5e-24
Identities = 85/287 (29%), Positives = 132/287 (45%), Gaps = 19/287 (6%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G +VY A+ + ++ IK D + F SL+ E + M +L+HPNI+ Y
Sbjct: 21 IGVGVSASVYKAICIPMNSMVVA--IKAIDLDQSRADFDSLRRETKTMSLLSHPNILNAY 78
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIED--EMVTQVYTLQLLEGLACLHQSGVVHR 1382
+ + M F SL S++ E V+ + L ++ LH G +HR
Sbjct: 79 CSFTVDRCLWVVMPFMSCGSLHSIVSSSFPSGLPENCISVFLKETLNAISYLHDQGHLHR 138
Query: 1383 DIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
DIK NIL+D +G +K DFG + I + + S + S D+ GTP +MAPE V
Sbjct: 139 DIKAGNILVDSDGSVKLADFGVSASIYEPVTS--SSGTTSSSLRLTDIAGTPYWMAPEVV 196
Query: 1443 TGQGHGKFG-SDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAG-HLPQFPTKS--- 1497
H +G DIWS G LE+ GR P ++L +++ + H + +
Sbjct: 197 --HSHTGYGFKADIWSFGITALELAHGRPPLSHLPPLKSLLMKITKRFHFSDYEINTSGS 254
Query: 1498 ------EISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNIAF 1538
+ S A R+ + CL QD KR +A +LL P+ + + F
Sbjct: 255 SKKGNKKFSKAFREMVGLCLEQDPTKRPSAEKLLKHPFFKNCKGLDF 301
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 112 bits (280), Expect = 5e-24
Identities = 77/267 (28%), Positives = 136/267 (50%), Gaps = 23/267 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GSFG V A ++ TG +A+K + + K+M ++ ++ E++++ + HP+I++ Y
Sbjct: 26 LGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNM-EMEEKVRREIKILRLFMHPHIIRQY 84
Query: 1325 GVEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
V + + ME+ + L ++E GR++++ + Q++ G+ H++ VVHRD
Sbjct: 85 EVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQ-QIISGVEYCHRNMVVHRD 143
Query: 1384 IKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVT 1443
+KPEN+LLD IK DFG + ++ + S G+P Y APE ++
Sbjct: 144 LKPENLLLDSRCNIKIADFGLSNVMRDGHFLKTS-------------CGSPNYAAPEVIS 190
Query: 1444 GQGHGKFGSD-DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSA 1502
G+ + G + D+WS G ++ ++ G P+ D ++ G + P S +SS
Sbjct: 191 GKLYA--GPEVDVWSCGVILYALLCGTLPFD--DENIPNLFKKIKGGIYTLP--SHLSSE 244
Query: 1503 GRKFISRCLIQDANKRATAMELLLDPW 1529
R I R LI D KR T E+ W
Sbjct: 245 ARDLIPRMLIVDPVKRITIPEIRQHRW 271
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 112 bits (280), Expect = 5e-24
Identities = 80/276 (28%), Positives = 134/276 (47%), Gaps = 19/276 (6%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQ-IFPSLKEEMRVMEILN 1316
+++ +G GSF VY A N+ +G+ +A+K I + K +K + +K E+ ++ +
Sbjct: 56 KYEIGKLLGHGSFAKVYLARNIHSGEDVAIKVIDKE--KIVKSGLAGHIKREISILRRVR 113
Query: 1317 HPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQ 1376
HP IV V + K+ I ME+ G L + + GR+ E + Y QL+ +A H
Sbjct: 114 HPYIVHLLEVMATKTKIYIVMEYVRGGELYNTVARGRLR-EGTARRYFQQLISSVAFCHS 172
Query: 1377 SGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
GV HRD+K EN+LLD G +K DFG + + + + I + GTP Y
Sbjct: 173 RGVYHRDLKLENLLLDDKGNVKVSDFGLSVVSEQLKQEGIC----------QTFCGTPAY 222
Query: 1437 MAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTK 1496
+APE +T +G+ + DIWS G ++ ++ G P+ D +MY + QF
Sbjct: 223 LAPEVLTRKGY-EGAKADIWSCGVILFVLMAGYLPFD--DKNILVMY--TKIYKGQFKCP 277
Query: 1497 SEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
S + ++R L + + R T E++ W +
Sbjct: 278 KWFSPELARLVTRMLDTNPDTRITIPEIMKHRWFKK 313
>HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1165
Score = 112 bits (279), Expect = 6e-24
Identities = 76/279 (27%), Positives = 142/279 (50%), Gaps = 33/279 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVME-ILNHPNIVQY 1323
+G+G++G VY ++ TG + A+K + + + + + +K E+ +++ +H NI Y
Sbjct: 31 VGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEE-----IKLEINMLKKYSHHRNIATY 85
Query: 1324 YGVEV------HRDKVNIFMEFCEGSSLASLLEHGR---IEDEMVTQVYTLQLLEGLACL 1374
YG + H D++ + MEFC S+ L+++ + ++++ + + + ++L GLA L
Sbjct: 86 YGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYI-SREILRGLAHL 144
Query: 1375 HQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
H V+HRDIK +N+LL N +K VDFG + + + +R IGTP
Sbjct: 145 HIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRR------------NTFIGTP 192
Query: 1435 MYMAPETVTGQGHGKFGSD---DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLP 1491
+MAPE + + D D+WS G +EM G P ++ + ++ + P
Sbjct: 193 YWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDM-HPMRALFLIPRNPPP 251
Query: 1492 QFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+ +K + S FI CL+++ +R + +LL P+I
Sbjct: 252 RLKSK-KWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFI 289
>Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1212
Score = 112 bits (279), Expect = 6e-24
Identities = 76/279 (27%), Positives = 142/279 (50%), Gaps = 33/279 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVME-ILNHPNIVQY 1323
+G+G++G VY ++ TG + A+K + + + + + +K E+ +++ +H NI Y
Sbjct: 31 VGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEE-----IKLEINMLKKYSHHRNIATY 85
Query: 1324 YGVEV------HRDKVNIFMEFCEGSSLASLLEHGR---IEDEMVTQVYTLQLLEGLACL 1374
YG + H D++ + MEFC S+ L+++ + ++++ + + + ++L GLA L
Sbjct: 86 YGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYI-SREILRGLAHL 144
Query: 1375 HQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
H V+HRDIK +N+LL N +K VDFG + + + +R IGTP
Sbjct: 145 HIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRR------------NTFIGTP 192
Query: 1435 MYMAPETVTGQGHGKFGSD---DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLP 1491
+MAPE + + D D+WS G +EM G P ++ + ++ + P
Sbjct: 193 YWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDM-HPMRALFLIPRNPPP 251
Query: 1492 QFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+ +K + S FI CL+++ +R + +LL P+I
Sbjct: 252 RLKSK-KWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFI 289
>Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1320
Score = 112 bits (279), Expect = 6e-24
Identities = 76/279 (27%), Positives = 142/279 (50%), Gaps = 33/279 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVME-ILNHPNIVQY 1323
+G+G++G VY ++ TG + A+K + + + + + +K E+ +++ +H NI Y
Sbjct: 31 VGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEE-----IKLEINMLKKYSHHRNIATY 85
Query: 1324 YGVEV------HRDKVNIFMEFCEGSSLASLLEHGR---IEDEMVTQVYTLQLLEGLACL 1374
YG + H D++ + MEFC S+ L+++ + ++++ + + + ++L GLA L
Sbjct: 86 YGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYI-SREILRGLAHL 144
Query: 1375 HQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
H V+HRDIK +N+LL N +K VDFG + + + +R IGTP
Sbjct: 145 HIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRR------------NTFIGTP 192
Query: 1435 MYMAPETVTGQGHGKFGSD---DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLP 1491
+MAPE + + D D+WS G +EM G P ++ + ++ + P
Sbjct: 193 YWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDM-HPMRALFLIPRNPPP 251
Query: 1492 QFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+ +K + S FI CL+++ +R + +LL P+I
Sbjct: 252 RLKSK-KWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFI 289
>Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1166
Score = 112 bits (279), Expect = 6e-24
Identities = 76/279 (27%), Positives = 142/279 (50%), Gaps = 33/279 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVME-ILNHPNIVQY 1323
+G+G++G VY ++ TG + A+K + + + + + +K E+ +++ +H NI Y
Sbjct: 31 VGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEE-----IKLEINMLKKYSHHRNIATY 85
Query: 1324 YGVEV------HRDKVNIFMEFCEGSSLASLLEHGR---IEDEMVTQVYTLQLLEGLACL 1374
YG + H D++ + MEFC S+ L+++ + ++++ + + + ++L GLA L
Sbjct: 86 YGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYI-SREILRGLAHL 144
Query: 1375 HQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
H V+HRDIK +N+LL N +K VDFG + + + +R IGTP
Sbjct: 145 HIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRR------------NTFIGTP 192
Query: 1435 MYMAPETVTGQGHGKFGSD---DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLP 1491
+MAPE + + D D+WS G +EM G P ++ + ++ + P
Sbjct: 193 YWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDM-HPMRALFLIPRNPPP 251
Query: 1492 QFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+ +K + S FI CL+++ +R + +LL P+I
Sbjct: 252 RLKSK-KWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFI 289
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 112 bits (279), Expect = 6e-24
Identities = 73/268 (27%), Positives = 137/268 (50%), Gaps = 22/268 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GSF V A+++ TG +A+K + K+M I ++ E++++ L HP+I++ Y
Sbjct: 25 LGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMG-IEIKVQREIKILRFLMHPHIIRQY 83
Query: 1325 GVEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
V + + + ME+ + L ++E G+++++ ++ Q++ G+ H++ +VHRD
Sbjct: 84 EVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQ-QIISGVEYCHRNMIVHRD 142
Query: 1384 IKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVT 1443
+KPEN+LLD IK VDFG + ++ + S G+P Y APE ++
Sbjct: 143 LKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTS-------------CGSPNYAAPEVIS 189
Query: 1444 GQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAG 1503
G+ +G DIWS G ++ ++ G P+ + +N + + G + + +S
Sbjct: 190 GKPYGP--DVDIWSCGVILYALLCGTLPFDD-ENIPNVFEKIKRG---MYTLPNHLSHFA 243
Query: 1504 RKFISRCLIQDANKRATAMELLLDPWIS 1531
R I R L+ D R + E+ PW +
Sbjct: 244 RDLIPRMLMVDPTMRISITEIRQHPWFN 271
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 112 bits (279), Expect = 6e-24
Identities = 85/261 (32%), Positives = 135/261 (51%), Gaps = 19/261 (7%)
Query: 1266 GSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPS--LKEEMRVMEILNHPNIVQY 1323
G GS+ V A D G + A +KI D K + + + +K E V++ L HP IV+
Sbjct: 49 GVGSYSKVVRAKKKDNGTVYA---LKIMDKKFITKENKTAYVKLERIVLDQLEHPGIVKL 105
Query: 1324 YGVEVHRDKVNIFMEFCEGSSLAS-LLEHGRI-EDEMVTQVYTLQLLEGLACLHQSGVVH 1381
+ + + +E CEG L + GR+ EDE + Y+ ++++ L +H G++H
Sbjct: 106 FFTFQDTQSLYMALESCEGGELFDQITRKGRLSEDE--ARFYSAEVVDALEYIHNMGLIH 163
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTG-GKDMIGTPMYMAPE 1440
RDIKPEN+LL +G IK DFG+ K + +I++ N S +GT Y+ PE
Sbjct: 164 RDIKPENLLLTLDGHIKIADFGSVKPMQ---DSQITVLPNAASDDKACTFVGTAAYVPPE 220
Query: 1441 TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEIS 1500
V FG +D+W+LGC + +M++G P+ + +EW I + A + +FP + S
Sbjct: 221 -VLNSSPATFG-NDLWALGCTLYQMLSGTSPFKDA-SEWLIFQRIIARDI-KFP--NHFS 274
Query: 1501 SAGRKFISRCLIQDANKRATA 1521
A R I R L D ++R A
Sbjct: 275 EAARDLIDRLLDTDPSRRPGA 295
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 112 bits (279), Expect = 6e-24
Identities = 75/267 (28%), Positives = 134/267 (50%), Gaps = 23/267 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GSFG V A + TG +A+K + + K+M ++ ++ E++++ + HP+I++ Y
Sbjct: 25 LGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNM-EMEEKVRREIKILRLFMHPHIIRLY 83
Query: 1325 GVEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
V + + ME+ L ++E GR++++ + Q++ G+ H++ VVHRD
Sbjct: 84 EVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQ-QIISGVEYCHRNMVVHRD 142
Query: 1384 IKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVT 1443
+KPEN+LLD +K DFG + ++ + S G+P Y APE ++
Sbjct: 143 LKPENLLLDSKCNVKIADFGLSNIMRDGHFLKTS-------------CGSPNYAAPEVIS 189
Query: 1444 GQGHGKFGSD-DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSA 1502
G+ + G + D+WS G ++ ++ G P+ D ++ G + P S +S
Sbjct: 190 GKLYA--GPEVDVWSCGVILYALLCGTLPFD--DENIPNLFKKIKGGIYTLP--SHLSPG 243
Query: 1503 GRKFISRCLIQDANKRATAMELLLDPW 1529
R I R L+ D KR T E+ PW
Sbjct: 244 ARDLIPRMLVVDPMKRVTIPEIRQHPW 270
>Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1295
Score = 111 bits (278), Expect = 8e-24
Identities = 78/279 (27%), Positives = 140/279 (49%), Gaps = 33/279 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVME-ILNHPNIVQY 1323
+G+G++G VY ++ TG + A+K + + + + + +K+E+ +++ +H NI Y
Sbjct: 31 VGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEE-----IKQEINMLKKYSHHRNIATY 85
Query: 1324 YGVEVHR------DKVNIFMEFCEGSSLASLLEHGR---IEDEMVTQVYTLQLLEGLACL 1374
YG + + D++ + MEFC S+ L+++ + ++++ + + ++L GLA L
Sbjct: 86 YGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICR-EILRGLAHL 144
Query: 1375 HQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
H V+HRDIK +N+LL N +K VDFG + + + +R IGTP
Sbjct: 145 HAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRR------------NTFIGTP 192
Query: 1435 MYMAPETVTGQGHGKFGSD---DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLP 1491
+MAPE + + D DIWSLG +EM G P ++ + ++ + P
Sbjct: 193 YWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDM-HPMRALFLIPRNPPP 251
Query: 1492 QFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+ +K + S FI CLI+ R +LL P+I
Sbjct: 252 RLKSK-KWSKKFIDFIDTCLIKTYLSRPPTEQLLKFPFI 289
>Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1050
Score = 111 bits (278), Expect = 8e-24
Identities = 75/282 (26%), Positives = 133/282 (46%), Gaps = 29/282 (10%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHP 1318
+ ++ IG G+F V+ + + D+ +K + K++ + L +E+++++ L H
Sbjct: 16 FSRKDLIGHGAFAVVFKGRHREKHDLEVA--VKCINKKNLAKSQTLLGKEIKILKELKHE 73
Query: 1319 NIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSG 1378
NIV Y + + V + ME+C G LA L R E +++ Q+ + LH G
Sbjct: 74 NIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKG 133
Query: 1379 VVHRDIKPENILLDR--------NGV-IKYVDFGAAKLIAKNGSKRISLDANNKSTGGKD 1429
++HRD+KP+NILL N + +K DFG A+ + N
Sbjct: 134 IIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSN-------------MMAAT 180
Query: 1430 MIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW-ANLDNEWAIMYHVAAG 1488
+ G+PMYMAPE + Q + G D+WS+G +V + +TG+ P+ A+ + + Y
Sbjct: 181 LCGSPMYMAPEVIMSQHYD--GKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKT 238
Query: 1489 HLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+P P E S+ R+ + L ++ R E P++
Sbjct: 239 LVPTIP--RETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFL 278
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 111 bits (278), Expect = 8e-24
Identities = 84/269 (31%), Positives = 133/269 (49%), Gaps = 24/269 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEI---KIQDAKSMKQIFPSLKEEMRVMEILNHPNIV 1321
+G G+FG V A + +G AVK I +I D QI K E+R +++L HP+IV
Sbjct: 26 LGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQI----KREIRTLKMLKHPHIV 81
Query: 1322 QYYGVEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVV 1380
+ + V + K+N+ ME G L ++ +G++ + +++ QL++G++ H GV
Sbjct: 82 RLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQ-QLIDGISYCHSKGVF 140
Query: 1381 HRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPE 1440
HRD+K EN+LLD G IK DFG + L + D +T G+P Y+APE
Sbjct: 141 HRDLKLENVLLDAKGHIKITDFGLSAL-----PQHFRDDGLLHTT-----CGSPNYVAPE 190
Query: 1441 TVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEIS 1500
+ +G+ S DIWS G ++ ++TG P+ D A++Y P P +S
Sbjct: 191 VLANRGYDGAAS-DIWSCGVILYVILTGCLPFD--DRNLAVLYQKICKGDPPIP--RWLS 245
Query: 1501 SAGRKFISRCLIQDANKRATAMELLLDPW 1529
R I R L + R T + + W
Sbjct: 246 PGARTMIKRMLDPNPVTRITVVGIKASEW 274
>YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 506
Score = 111 bits (277), Expect = 1e-23
Identities = 92/287 (32%), Positives = 137/287 (47%), Gaps = 46/287 (16%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQ--DAKSMKQIFPSLKEEMRVMEILNHPNIVQ 1322
+G G+ G+V + + A+K I D + KQIF E++ + IVQ
Sbjct: 220 LGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIF----RELQFNKSFKSDYIVQ 275
Query: 1323 YYGVEVHRDKVNIF--MEFCEGSSLASLLEH-----GRIEDEMVTQVYTLQLLEGLACLH 1375
YYG+ +I+ ME+ G SL + ++ GRI + ++ ++ +L GL+ LH
Sbjct: 276 YYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAE-SVLRGLSYLH 334
Query: 1376 QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
+ V+HRDIKP+NILL+ G IK DFG +S +A N GT
Sbjct: 335 ERKVIHRDIKPQNILLNEKGEIKLCDFG------------VSGEAVNSL--AMTFTGTSF 380
Query: 1436 YMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHL----- 1490
YMAPE + GQ + + D+WSLG +LE+ GR P+ I +VA L
Sbjct: 381 YMAPERIQGQPYSV--TCDVWSLGLTLLEVAGGRFPF----ESDKITQNVAPIELLTMIL 434
Query: 1491 ---PQFPTKSEI----SSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
PQ + E+ S R FI CL +DA +R + ++L PWI
Sbjct: 435 TFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWI 481
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 111 bits (277), Expect = 1e-23
Identities = 79/272 (29%), Positives = 130/272 (47%), Gaps = 23/272 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G+GSFG V+ + G A+K +K + +KQ+ +E ++ I+ HP I++ +
Sbjct: 93 LGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQV-EHTNDERLMLSIVTHPFIIRMW 151
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
G ++ + M++ EG L SLL + V + Y ++ L LH +++RD+
Sbjct: 152 GTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDL 211
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
KPENILLD+NG IK DFG AK + D + GTP Y+APE V+
Sbjct: 212 KPENILLDKNGHIKITDFGFAKYVP---------DVT------YTLCGTPDYIAPEVVST 256
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPT--KSEISSA 1502
+ + K S D WS G ++ EM+ G P+ D+ Y +FP ++
Sbjct: 257 KPYNK--SIDWWSFGILIYEMLAGYTPF--YDSNTMKTYEKILNAELRFPPFFNEDVKDL 312
Query: 1503 GRKFISRCLIQD-ANKRATAMELLLDPWISQI 1533
+ I+R L Q N + ++ PW ++
Sbjct: 313 LSRLITRDLSQRLGNLQNGTEDVKNHPWFKEV 344
>Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 878
Score = 111 bits (277), Expect = 1e-23
Identities = 89/278 (32%), Positives = 134/278 (48%), Gaps = 35/278 (12%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPS-----LKEEMRVMEILNHPN 1319
+GSG FG VY + TG +AVK I K FP+ L+ E+ +++ L HP
Sbjct: 557 LGSGQFGVVYGGKHRKTGRDVAVKVID-------KLRFPTKQESQLRNEVAILQSLRHPG 609
Query: 1320 IVQYYGVEVHRDKVNIFMEFCEGSSLASLL--EHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
IV + +KV + ME G L +L E GR+ E +T+ Q+L L LH
Sbjct: 610 IVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLP-ERLTKFLITQILVALRHLHFK 668
Query: 1378 GVVHRDIKPENILL---DRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
+VH D+KPEN+LL D +K DFG A++I + +R ++GTP
Sbjct: 669 NIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRR-------------SVVGTP 715
Query: 1435 MYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFP 1494
Y+APE + QG+ + S D+WS+G ++ ++G P+ N D + AA P P
Sbjct: 716 AYLAPEVLLNQGYNR--SLDMWSVGVIMYVSLSGTFPF-NEDEDINDQIQNAAFMYPASP 772
Query: 1495 TKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQ 1532
S IS+ I+ L KR + + L PW+ +
Sbjct: 773 W-SHISAGAIDLINNLLQVKMRKRYSVDKSLSHPWLQE 809
>Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 992
Score = 111 bits (277), Expect = 1e-23
Identities = 86/274 (31%), Positives = 137/274 (49%), Gaps = 32/274 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+GSG FG V+ V T + A K K AK + I ++E+ +M L+HP +VQ
Sbjct: 548 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENI----RQEISIMNCLHHPKLVQC- 602
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQ----VYTLQLLEGLACLHQSGVV 1380
V+ +K NI M E S L E ED +T+ Y Q+ EG+ +H+ G+V
Sbjct: 603 -VDAFEEKANIVMVL-EIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIV 660
Query: 1381 HRDIKPENIL-LDRNGV-IKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMA 1438
H D+KPENI+ +++ G IK +DFG A+ + GS ++ + GTP ++A
Sbjct: 661 HLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV-------------LFGTPEFVA 707
Query: 1439 PETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKS- 1497
PE + + G + D+WS+G + +V+G P+ DN+ + +V + F ++
Sbjct: 708 PEVINYEPIGY--ATDMWSIGVICYILVSGLSPFMG-DNDNETLANVTSATW-DFDDEAF 763
Query: 1498 -EISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
EIS + FIS L +D R + L PW+
Sbjct: 764 DEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWL 797
>Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1845
Score = 111 bits (277), Expect = 1e-23
Identities = 86/274 (31%), Positives = 137/274 (49%), Gaps = 32/274 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+GSG FG V+ V T + A K K AK + I ++E+ +M L+HP +VQ
Sbjct: 1401 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENI----RQEISIMNCLHHPKLVQC- 1455
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQ----VYTLQLLEGLACLHQSGVV 1380
V+ +K NI M E S L E ED +T+ Y Q+ EG+ +H+ G+V
Sbjct: 1456 -VDAFEEKANIVMVL-EIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIV 1513
Query: 1381 HRDIKPENIL-LDRNGV-IKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMA 1438
H D+KPENI+ +++ G IK +DFG A+ + GS ++ + GTP ++A
Sbjct: 1514 HLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV-------------LFGTPEFVA 1560
Query: 1439 PETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKS- 1497
PE + + G + D+WS+G + +V+G P+ DN+ + +V + F ++
Sbjct: 1561 PEVINYEPIGY--ATDMWSIGVICYILVSGLSPFMG-DNDNETLANVTSATW-DFDDEAF 1616
Query: 1498 -EISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
EIS + FIS L +D R + L PW+
Sbjct: 1617 DEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWL 1650
>Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1914
Score = 111 bits (277), Expect = 1e-23
Identities = 86/274 (31%), Positives = 137/274 (49%), Gaps = 32/274 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+GSG FG V+ V T + A K K AK + I ++E+ +M L+HP +VQ
Sbjct: 1470 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENI----RQEISIMNCLHHPKLVQC- 1524
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQ----VYTLQLLEGLACLHQSGVV 1380
V+ +K NI M E S L E ED +T+ Y Q+ EG+ +H+ G+V
Sbjct: 1525 -VDAFEEKANIVMVL-EIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIV 1582
Query: 1381 HRDIKPENIL-LDRNGV-IKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMA 1438
H D+KPENI+ +++ G IK +DFG A+ + GS ++ + GTP ++A
Sbjct: 1583 HLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV-------------LFGTPEFVA 1629
Query: 1439 PETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKS- 1497
PE + + G + D+WS+G + +V+G P+ DN+ + +V + F ++
Sbjct: 1630 PEVINYEPIGY--ATDMWSIGVICYILVSGLSPFMG-DNDNETLANVTSATW-DFDDEAF 1685
Query: 1498 -EISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
EIS + FIS L +D R + L PW+
Sbjct: 1686 DEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWL 1719
>Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 991
Score = 111 bits (277), Expect = 1e-23
Identities = 86/274 (31%), Positives = 137/274 (49%), Gaps = 32/274 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+GSG FG V+ V T + A K K AK + I ++E+ +M L+HP +VQ
Sbjct: 548 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENI----RQEISIMNCLHHPKLVQC- 602
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQ----VYTLQLLEGLACLHQSGVV 1380
V+ +K NI M E S L E ED +T+ Y Q+ EG+ +H+ G+V
Sbjct: 603 -VDAFEEKANIVMVL-EIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIV 660
Query: 1381 HRDIKPENIL-LDRNGV-IKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMA 1438
H D+KPENI+ +++ G IK +DFG A+ + GS ++ + GTP ++A
Sbjct: 661 HLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV-------------LFGTPEFVA 707
Query: 1439 PETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKS- 1497
PE + + G + D+WS+G + +V+G P+ DN+ + +V + F ++
Sbjct: 708 PEVINYEPIGY--ATDMWSIGVICYILVSGLSPFMG-DNDNETLANVTSATW-DFDDEAF 763
Query: 1498 -EISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
EIS + FIS L +D R + L PW+
Sbjct: 764 DEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWL 797
>At3g20860 [R] KOG0589 Serine/threonine protein kinase
Length = 427
Score = 111 bits (277), Expect = 1e-23
Identities = 82/280 (29%), Positives = 137/280 (48%), Gaps = 28/280 (10%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G+FG+ + ++ VK+I++ AK ++ + +EM ++ L P IV+Y
Sbjct: 21 IGRGAFGSAFLVIHKSERRKYVVKKIRL--AKQTERCKLAAIQEMSLISKLKSPYIVEYK 78
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGR---IEDEMVTQVYTLQLLEGLACLHQSGVVH 1381
V +D V I +CEG + +++ R +E + + + +QLL + LH + V+H
Sbjct: 79 DSWVEKDCVCIVTSYCEGGDMTQMIKKSRGVFASEEKLCR-WMVQLLLAIDYLHNNRVLH 137
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
RD+K NI L + ++ DFG AKL+ K+ M+GTP YM PE
Sbjct: 138 RDLKCSNIFLTKENEVRLGDFGLAKLLGKDDL-------------ASSMVGTPNYMCPEL 184
Query: 1442 VTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISS 1501
+ +G DIWSLGC + E V +P + A++ + L P SS
Sbjct: 185 LADIPYGY--KSDIWSLGCCMFE-VAAHQPAFKAPDMAALINKINRSSLSPLPVM--YSS 239
Query: 1502 AGRKFISRCLIQDANKRATAMELL----LDPWISQIRNIA 1537
+ ++ I L ++ R TA ELL L P+++Q +N++
Sbjct: 240 SLKRLIKSMLRKNPEHRPTAAELLRHPHLQPYLAQCQNLS 279
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 534
Score = 111 bits (277), Expect = 1e-23
Identities = 81/280 (28%), Positives = 131/280 (45%), Gaps = 33/280 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G G FG Y + G A K I + K I +E M + + PNIV++
Sbjct: 91 LGRGQFGITYKCTDKSNGREYACKSISKRKLIRRKDIEDVRREVMILQHLTGQPNIVEFR 150
Query: 1325 GVEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
G +D +++ ME C G L +++ G ++ ++ Q++ + H GVVHRD
Sbjct: 151 GAYEDKDNLHLVMELCSGGELFDRIIKKGSYSEKEAANIFR-QIVNVVHVCHFMGVVHRD 209
Query: 1384 IKPENILL---DRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPE 1440
+KPEN LL + + IK DFG + I + R D++G+ Y+APE
Sbjct: 210 LKPENFLLVSNEEDSPIKATDFGLSVFIEEGKVYR-------------DIVGSAYYVAPE 256
Query: 1441 TVTGQGHGKFGSD-DIWSLGCVVLEMVTGRRP-WANLDNEWAIMYHVAAGHL----PQFP 1494
+ H +G + D+WS G ++ +++G P W + E I + G L +P
Sbjct: 257 VL----HRNYGKEIDVWSAGVMLYILLSGVPPFWG--ETEKTIFEAILEGKLDLETSPWP 310
Query: 1495 TKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIR 1534
T IS + + I + LI+D KR TA E L PW++ +
Sbjct: 311 T---ISESAKDLIRKMLIRDPKKRITAAEALEHPWMTDTK 347
>CE21086 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 637
Score = 110 bits (276), Expect = 1e-23
Identities = 81/275 (29%), Positives = 137/275 (49%), Gaps = 29/275 (10%)
Query: 1265 IGSGSFGTVYSAVNLDTGD-ILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILN---HPNI 1320
+G GSF V + T + + A+KEI I S+K E + + L+ H N+
Sbjct: 24 LGEGSFAEVVLVAKVGTPNKMFAMKEISIVGKDEC--FMESIKRECSIQKRLSKSRHLNM 81
Query: 1321 VQYYGVEVHRDKVNIFMEFCEGSSLASLL-EHGRIEDEMVTQVYTLQLLEGLACLHQSGV 1379
+ + + + + + + + +G L + +HG + + + Y QL++GL +H+ GV
Sbjct: 82 IHLFEIRTNPENYQLILSYADGGDLFEKINQHGGLGSDEAHR-YFKQLIDGLRFIHEEGV 140
Query: 1380 VHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAP 1439
HRDIKPEN+LL ++G++K DFG A + NG++++ L+A G+P Y+AP
Sbjct: 141 THRDIKPENLLLTKSGILKIADFGFATMHRFNGAEQM-LNA---------YCGSPPYIAP 190
Query: 1440 ETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQF---PTK 1496
E +TG + + + DIWS G V++ M+ G PW D+ + + F K
Sbjct: 191 EVLTGIDY-RGPAVDIWSAGVVLIAMIAGAVPWEQADH-----FDIFQSRYCSFRRNGRK 244
Query: 1497 SEISSAGRKFIS--RCLIQDANKRATAMELLLDPW 1529
S ++ IS R ++ A RAT + DPW
Sbjct: 245 GAWSRMSQQVISLLRKILLQAELRATISMIEEDPW 279
Score = 94.0 bits (232), Expect = 2e-18
Identities = 81/274 (29%), Positives = 123/274 (44%), Gaps = 26/274 (9%)
Query: 1268 GSFGTVYSAVNLDTGDI-LAVKEIKIQDAKSMKQIFPSLKEEM--RVMEILNHPNIVQYY 1324
GSFG V+ + +AVKE+ + KS K + KE R + + H N++Q
Sbjct: 352 GSFGQVHLCELTRNPSVKVAVKEVAVS-GKSRKNLTAVQKEYKIHRRLSKIGHENVIQMM 410
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ ++ ME+ +G L L+ Y QL++GL +H+ G+VHRDI
Sbjct: 411 KMIETPKFYSLVMEYADGGDLFDELKEQEKFSRKDAHSYFKQLIKGLKFIHEQGIVHRDI 470
Query: 1385 KPENILL------DRNGVIKYVDFGAAKLIAKNGSK-RISLDANNKSTGGKDMIGTPMYM 1437
K EN+LL D G +K DFG A K+G + +S D +K Y
Sbjct: 471 KLENLLLVYSESEDDPGTLKITDFGLATKYRKDGEEIMLSEDCGSKP-----------YA 519
Query: 1438 APETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW--ANLDNEWAIMYHVAAGHLPQFPT 1495
APE TG + + DIWS G V++ M+ G W AN + + A + A +
Sbjct: 520 APEVCTGNDY-RGPPVDIWSAGVVLMTMLVGEHSWKVANKEKDAAYSNWINAKD-EKANL 577
Query: 1496 KSEISSAGRKFISRCLIQDANKRATAMELLLDPW 1529
+ IS + + L + KRAT ++ DPW
Sbjct: 578 WNVISGPTTALLRKLLHANPEKRATMAKIEADPW 611
>At3g18750 [R] KOG0584 Serine/threonine protein kinase
Length = 567
Score = 110 bits (276), Expect = 1e-23
Identities = 82/274 (29%), Positives = 137/274 (49%), Gaps = 24/274 (8%)
Query: 1262 RSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIV 1321
+ IG G+F TVY A + G +A +++I D L E+R+++ L H NI+
Sbjct: 31 KEVIGKGAFKTVYKAFDEVDGIEVAWNQVRIDDVLQSPNCLERLYSEVRLLKSLKHNNII 90
Query: 1322 QYYG--VEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLH--QS 1377
++Y ++ VNI E SL + R + + + Q+L GL LH +
Sbjct: 91 RFYNSWIDDKNKTVNIITELFTSGSLRHYRKKHRKVNMKAVKNWARQILMGLRYLHGQEP 150
Query: 1378 GVVHRDIKPENILLDRN-GVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
++HRD+K +NI ++ N G +K D G A ++ + K +IGTP +
Sbjct: 151 PIIHRDLKCDNIFINGNHGEVKIGDLGLATVM--------------EQANAKSVIGTPEF 196
Query: 1437 MAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTK 1496
MAPE + + + + DI+S G +LEMVT P+ N I V++G P ++
Sbjct: 197 MAPE-LYDENYNELA--DIYSFGMCMLEMVTFDYPYCECKNSAQIYKKVSSGIKPASLSR 253
Query: 1497 SEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+ ++FI +CL+ A++R +A ELLLDP++
Sbjct: 254 VKDPEV-KQFIEKCLL-PASERLSAKELLLDPFL 285
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 110 bits (276), Expect = 1e-23
Identities = 63/216 (29%), Positives = 111/216 (51%), Gaps = 19/216 (8%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEI--KIQDAKSMKQIFPSLKEEMRVMEILN 1316
+++ F G G F Y ++++T D+ A K + K+ + K+ +E+ + LN
Sbjct: 25 YKRMRFFGKGGFAKCYEIIDVETDDVFAGKIVSKKLMIKHNQKE---KTAQEITIHRSLN 81
Query: 1317 HPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQ 1376
HPNIV+++ + I +E C+ S+ L + + E + Y Q+++G+ LH
Sbjct: 82 HPNIVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSITEFECRYYIYQIIQGVKYLHD 141
Query: 1377 SGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
+ ++HRD+K N+ L+ +K DFG A I G ++ K + GTP Y
Sbjct: 142 NRIIHRDLKLGNLFLNDLLHVKIGDFGLATRIEYEGERK------------KTLCGTPNY 189
Query: 1437 MAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW 1472
+APE +T +GH DIWS+GCV+ ++ G+ P+
Sbjct: 190 IAPEILTKKGHS--FEVDIWSIGCVMYTLLVGQPPF 223
>At5g27790 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 327
Score = 110 bits (275), Expect = 2e-23
Identities = 95/281 (33%), Positives = 136/281 (47%), Gaps = 35/281 (12%)
Query: 1262 RSFIGSGSFGTV--YSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPN 1319
R G GSFG+V +S G+ L DAKS+ + F L + P
Sbjct: 23 RKVFGKGSFGSVRLFSYKRRCDGETLYATVKTSDDAKSLYEEFQILSK------FKGCPR 76
Query: 1320 IVQYYGVEVHR---DK----VNIFMEFCEGSSLASLLEH---GRIEDEMVTQVYTLQLLE 1369
IVQ YG V + DK I ME+ G SL + ++ ++ D M+ + +T LLE
Sbjct: 77 IVQCYGNGVKQRFNDKGYVEYMIPMEYATGGSLNNFMDRFNDRKLPDPMIRK-FTRMLLE 135
Query: 1370 GLACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGG-- 1427
GLA +H+ G VH DIKPENIL+ V K GA + K L + T
Sbjct: 136 GLATIHRYGYVHYDIKPENILVFPGSVYKE---GAWRYSYKLKISDFGLSKRDGDTKWWH 192
Query: 1428 --KDMIGTPMYMAPETVTGQGHGKFGSD-DIWSLGCVVLEMVTGRRPWANLDNEWAIMYH 1484
K GT +YM+PE+++ HG+ G D+WSLGCVVLEM TG+RPW + + E +
Sbjct: 193 PLKSYAGTRIYMSPESIS---HGEIGKGLDLWSLGCVVLEMYTGKRPWWHTNYE---LED 246
Query: 1485 VAAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELL 1525
+ + P FP + + F+ C + ++R A+ LL
Sbjct: 247 LMKCYEPLFP--PNLPCDAKLFLMTCFAPEPDERKDALTLL 285
>At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 531
Score = 110 bits (275), Expect = 2e-23
Identities = 84/274 (30%), Positives = 134/274 (48%), Gaps = 29/274 (10%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILN-HPNIVQY 1323
+G G FG Y + TG+ A K I + S KQ +K E+++M+ L+ PNIV+
Sbjct: 86 LGRGQFGITYMCKEIGTGNTYACKSILKRKLIS-KQDKEDVKREIQIMQYLSGQPNIVEI 144
Query: 1324 YGVEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHR 1382
G R +++ ME C G L ++ G + + ++ + H GVVHR
Sbjct: 145 KGAYEDRQSIHLVMELCAGGELFDRIIAQGHYSERAAAGIIR-SIVNVVQICHFMGVVHR 203
Query: 1383 DIKPENILL---DRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAP 1439
D+KPEN LL + N ++K DFG + I + R D++G+ Y+AP
Sbjct: 204 DLKPENFLLSSKEENAMLKATDFGLSVFIEEGKVYR-------------DIVGSAYYVAP 250
Query: 1440 ETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRP-WANLDNEWAIMYHVAAGHLPQFPTK-- 1496
E V + +GK DIWS G ++ +++G P WA +NE I V G + F ++
Sbjct: 251 E-VLRRSYGK--EIDIWSAGVILYILLSGVPPFWA--ENEKGIFDEVIKGEI-DFVSEPW 304
Query: 1497 SEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
IS + + + + L +D +R TA ++L PWI
Sbjct: 305 PSISESAKDLVRKMLTKDPKRRITAAQVLEHPWI 338
>At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 599
Score = 110 bits (275), Expect = 2e-23
Identities = 86/288 (29%), Positives = 142/288 (48%), Gaps = 41/288 (14%)
Query: 1265 IGSGSFGTVYSAVNLDTGDI----LAVKEI---KIQDAKSMKQIFPSLKEEMRVMEILN- 1316
IG G FG SA G++ +AVK I K+ A S++ + + E++++ L+
Sbjct: 150 IGRGHFGYTCSA-KFKKGELKDQEVAVKVIPKSKMTSAISIEDV----RREVKILRALSG 204
Query: 1317 HPNIVQYYGVEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLH 1375
H N+VQ+Y V I ME C G L +L G E + +Q+L +A H
Sbjct: 205 HQNLVQFYDAFEDNANVYIVMELCGGGELLDRILARGGKYSEDDAKAVLIQILNVVAFCH 264
Query: 1376 QSGVVHRDIKPENILL---DRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIG 1432
GVVHRD+KPEN L + N ++K +DFG + + + +R++ D++G
Sbjct: 265 LQGVVHRDLKPENFLYTSKEENSMLKVIDFGLSDFVRPD--ERLN-----------DIVG 311
Query: 1433 TPMYMAPETVTGQGHGKFGSD-DIWSLGCVVLEMVTGRRP-WANLDNEWAIMYHVAAGHL 1490
+ Y+APE + H + ++ D+WS+G + ++ G RP WA ++ ++
Sbjct: 312 SAYYVAPEVL----HRSYTTEADVWSIGVIAYILLCGSRPFWARTESG---IFRAVLKAD 364
Query: 1491 PQF--PTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNI 1536
P F P +S + F+ R L +D KR TA + L+ PWI+ + I
Sbjct: 365 PSFDEPPWPSLSFEAKDFVKRLLYKDPRKRMTASQALMHPWIAGYKKI 412
>YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 508
Score = 110 bits (274), Expect = 2e-23
Identities = 91/289 (31%), Positives = 137/289 (46%), Gaps = 36/289 (12%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKI--QDAKSMKQIFPSLKEEMRVMEIL 1315
R + +G G+ G+V + I A+K I D + KQIF E++
Sbjct: 220 RIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIF----RELQFNRSF 275
Query: 1316 NHPNIVQYYGVEVHRDKVNIF--MEFCEGSSL----ASLLEHGRIEDEMVTQVYTLQLLE 1369
IV+YYG+ + +I+ ME+ G SL +LLE G E V +L
Sbjct: 276 QSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLR 335
Query: 1370 GLACLHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKD 1429
GL+ LH+ V+HRDIKP+NILL+ NG +K DFG +S +A N
Sbjct: 336 GLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFG------------VSGEAVNSL--ATT 381
Query: 1430 MIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW------ANLDNEWAIMY 1483
GT YMAPE + GQ + + D+WSLG +LE+ G+ P AN+ +M+
Sbjct: 382 FTGTSFYMAPERIQGQPYSV--TSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMW 439
Query: 1484 HVA-AGHLPQFPTKSEI-SSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+ L P + I S + + FI CL +D+ +R + +++ PWI
Sbjct: 440 ILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWI 488
>Hs4506889 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kinase MKK4
Length = 399
Score = 110 bits (274), Expect = 2e-23
Identities = 92/278 (33%), Positives = 139/278 (49%), Gaps = 30/278 (10%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQ-DAKSMKQIFPSLKEEMRVMEILNHPNIVQY 1323
IG G++G+V V+ +G I+AVK I+ D K KQ+ L MR + P IVQ+
Sbjct: 108 IGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDC---PYIVQF 164
Query: 1324 YGVEVHRDKVNIFMEFCEGSS------LASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
YG I ME S + S+L+ I +E++ ++ TL ++ L L ++
Sbjct: 165 YGALFREGDCWICMELMSTSFDKFYKYVYSVLDDV-IPEEILGKI-TLATVKALNHLKEN 222
Query: 1378 -GVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMY 1436
++HRDIKP NILLDR+G IK DFG + + + +K + DA G Y
Sbjct: 223 LKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAK--TRDA-----------GCRPY 269
Query: 1437 MAPETV--TGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFP 1494
MAPE + + G D+WSLG + E+ TGR P+ ++ + + V G PQ
Sbjct: 270 MAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLS 329
Query: 1495 T--KSEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
+ E S + F++ CL +D +KR ELL P+I
Sbjct: 330 NSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFI 367
>Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 456
Score = 110 bits (274), Expect = 2e-23
Identities = 83/272 (30%), Positives = 140/272 (50%), Gaps = 28/272 (10%)
Query: 1266 GSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYYG 1325
G G FG V+ TG LA K IK + K +++ K E+ VM L+H N++Q Y
Sbjct: 181 GRGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEEV----KNEISVMNQLDHANLIQLYD 236
Query: 1326 VEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
++ + + ME+ +G L +++ E+ T ++ Q+ EG+ +HQ ++H D+
Sbjct: 237 AFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQICEGIRHMHQMYILHLDL 296
Query: 1385 KPENIL-LDRNG-VIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETV 1442
KPENIL ++R+ IK +DFG +A+ R L N GTP ++APE V
Sbjct: 297 KPENILCVNRDAKQIKIIDFG----LARRYKPREKLKVN---------FGTPEFLAPEVV 343
Query: 1443 TGQGHGKFGS--DDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLP-QFPTKSEI 1499
+ F S D+WS+G + +++G P+ DN+ + ++ A + +I
Sbjct: 344 ----NYDFVSFPTDMWSVGVIAYMLLSGLSPFLG-DNDAETLNNILACRWDLEDEEFQDI 398
Query: 1500 SSAGRKFISRCLIQDANKRATAMELLLDPWIS 1531
S ++FIS+ LI++ + R +A E L PW+S
Sbjct: 399 SEEAKEFISKLLIKEKSWRISASEALKHPWLS 430
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 348
Score = 110 bits (274), Expect = 2e-23
Identities = 82/278 (29%), Positives = 132/278 (46%), Gaps = 23/278 (8%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNL-DTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILN 1316
++ R +G+G+F V+ A + D G + AVK I D K++K SL+ E++V+ L
Sbjct: 21 KYDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCI---DKKALKGKEESLENEIKVLRKLR 77
Query: 1317 HPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQ 1376
H NIVQ + + V + ME G L + E Q+LE + +H
Sbjct: 78 HNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEAVGFMHD 137
Query: 1377 SGVVHRDIKPENILL---DRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGT 1433
+GVVHRD+KPEN+L D + I DFG +K + D+ +T GT
Sbjct: 138 NGVVHRDLKPENLLYYNQDEDSKIMISDFGLSK----------TEDSGVMATA----CGT 183
Query: 1434 PMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQF 1493
P Y+APE + + +GK + D+WS+G + ++ G P+ + + + +
Sbjct: 184 PGYVAPEVLQQKPYGK--AVDVWSIGVIAYILLCGYPPFYDESDANLFAQIIKGEYEFDA 241
Query: 1494 PTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWIS 1531
P +IS + + FI+ + D R T + L PWIS
Sbjct: 242 PYWDQISDSAKDFITHLMCCDPEARFTCQDALSHPWIS 279
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 110 bits (274), Expect = 2e-23
Identities = 74/254 (29%), Positives = 122/254 (47%), Gaps = 19/254 (7%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G G+FG V T + A+K +K + ++ +L E RV++ NHP ++
Sbjct: 191 LGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTES-RVLKSTNHPFLISLK 249
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
D++ M++ G L L H RI E T+ Y +++ L LH G+++RD+
Sbjct: 250 YSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDL 309
Query: 1385 KPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVTG 1444
K EN+LLD++G IK DFG K G K GTP Y+APE +
Sbjct: 310 KLENLLLDKDGHIKVADFGLCKEDITYGRTT------------KTFCGTPEYLAPEVLDD 357
Query: 1445 QGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAGR 1504
+G+ + D W G V+ EM+ GR P+ N D++ +++ + +FP I+ +
Sbjct: 358 NDYGQ--AVDWWGTGVVMYEMICGRLPFYNRDHD--VLFTLILVEEVKFP--RNITDEAK 411
Query: 1505 KFISRCLIQDANKR 1518
++ L +D KR
Sbjct: 412 NLLAGLLAKDPKKR 425
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 109 bits (273), Expect = 3e-23
Identities = 77/266 (28%), Positives = 132/266 (48%), Gaps = 26/266 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEI---KIQDAKSMKQIFPSLKEEMRVMEILNHPNIV 1321
IG G F + V + G+I A K I +Q+ K+ ++F E++V + ++HPNIV
Sbjct: 47 IGEGGFARCFR-VKDNYGNIYAAKVIAKRSLQNDKTKLKLFG----EIKVHQSMSHPNIV 101
Query: 1322 QYYGVEVHRDKVNIFM--EFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGV 1379
+ ++ D NI++ E CE SL LL + E + +Q+L L +H+ V
Sbjct: 102 GF--IDCFEDSTNIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQILGALKYMHKKRV 159
Query: 1380 VHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAP 1439
+HRD+K NI+LD + +K DFG A L+ + +++++ GTP Y+AP
Sbjct: 160 IHRDLKLGNIMLDESNNVKIGDFGLAALLMDDEERKMTI------------CGTPNYIAP 207
Query: 1440 ETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEI 1499
E + G D+WS G V+ ++ G+ P+ D E +Y + FP+ +I
Sbjct: 208 EILFNSKEGHSFEVDLWSAGVVMYALLIGKPPFQ--DKEVKTIYRKIKANSYSFPSNVDI 265
Query: 1500 SSAGRKFISRCLIQDANKRATAMELL 1525
S+ + IS L D + R + +++
Sbjct: 266 SAEAKDLISSLLTHDPSIRPSIDDIV 291
>Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 795
Score = 109 bits (273), Expect = 3e-23
Identities = 78/274 (28%), Positives = 135/274 (48%), Gaps = 26/274 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G G FG V+ TG LA K IK++ AK + + K E+ +M L+H N++Q Y
Sbjct: 497 LGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDV----KNEINIMNQLSHVNLIQLY 552
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIE-DEMVTQVYTLQLLEGLACLHQSGVVHRD 1383
+ + ME+ +G L + + E+ ++T Q+ EG+ LHQ ++H D
Sbjct: 553 DAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLD 612
Query: 1384 IKPENIL-LDRNG-VIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
+KPENIL +++ G IK +DFG +A+ R L N GTP ++APE
Sbjct: 613 LKPENILCVNQTGHQIKIIDFG----LARRYKPREKLKVN---------FGTPEFLAPEV 659
Query: 1442 VTGQGHGKFGS--DDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEI 1499
V + +F S D+WS+G + +++G P+ + + + V T +
Sbjct: 660 V----NYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFEGL 715
Query: 1500 SSAGRKFISRCLIQDANKRATAMELLLDPWISQI 1533
S + F+SR L+++ + R +A + L W++ +
Sbjct: 716 SEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNL 749
>CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 545
Score = 109 bits (273), Expect = 3e-23
Identities = 84/279 (30%), Positives = 132/279 (47%), Gaps = 29/279 (10%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
IG G+ TV++A L + +A+K I ++ ++ L E++ M NHPN+V YY
Sbjct: 63 IGVGATATVFTAYCLPRNEKVAIKCINLEKCQTSVD---ELSHEIQAMSQCNHPNVVSYY 119
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEH-----GR------IEDEMVTQVYTLQLLEGLAC 1373
+ ++++ + M S+ +L+ G+ + DE+ ++L+GL
Sbjct: 120 TSFIAQEELWVVMRLLNCGSMLDILKRKVKAIGKEQAQFGVLDEVSIATVLREVLKGLEY 179
Query: 1374 LHQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGT 1433
H +G +HRDIK NILL +G I+ DFG + +A +G ++ +GT
Sbjct: 180 FHLNGQIHRDIKAGNILLADDGTIQIADFGVSGWLASSGGDL------SRQKVRHTFVGT 233
Query: 1434 PMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQF 1493
P +MAPE V Q G DIWSLG + +E+ TG P+ +M P
Sbjct: 234 PCWMAPE-VMEQVQGYDFKADIWSLGILAIELATGTAPYHKYPPMKVLML-TLQNDPPTL 291
Query: 1494 PT----KSEISSAGRKF---ISRCLIQDANKRATAMELL 1525
T K + + G+ F I CL +D KR TA ELL
Sbjct: 292 ETNAERKDQYKAYGKSFKTLIRDCLQKDPAKRPTASELL 330
>At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 523
Score = 109 bits (273), Expect = 3e-23
Identities = 85/291 (29%), Positives = 136/291 (46%), Gaps = 43/291 (14%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFP----SLKEEMRVMEILN-HPN 1319
+G G FG Y A++ GD +AVK + K + P +K E++++ L+ H N
Sbjct: 68 LGHGQFGYTYVAIHRPNGDRVAVKRLD-----KSKMVLPIAVEDVKREVQILIALSGHEN 122
Query: 1320 IVQYYGVEVHRDKVNIFMEFCEGSSLAS--LLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
+VQ++ D V I ME CEG L L + G E V Q+L+ H
Sbjct: 123 VVQFHNAFEDDDYVYIVMELCEGGELLDRILSKKGNRYSEKDAAVVVRQMLKVAGECHLH 182
Query: 1378 GVVHRDIKPENILL---DRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
G+VHRD+KPEN L + +K DFG + I K G + D++G+
Sbjct: 183 GLVHRDMKPENFLFKSAQLDSPLKATDFGLSDFI-KPGKR------------FHDIVGSA 229
Query: 1435 MYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRP-WANLDNEWAIMYHVAAGHLPQF 1493
Y+APE + + + D+WS+G + ++ GRRP W ++ ++ + P F
Sbjct: 230 YYVAPEVLKRRSGPE---SDVWSIGVITYILLCGRRPFWDRTEDG---IFKEVLRNKPDF 283
Query: 1494 PTK--SEISSAGRKFISRCLIQDANKRATAMELLLDPWISQIRNIAFGGNA 1542
K + IS + + F+ + L++D R TA + L W+ + GGNA
Sbjct: 284 SRKPWATISDSAKDFVKKLLVKDPRARLTAAQALSHAWVRE------GGNA 328
>At2g41930 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 351
Score = 109 bits (273), Expect = 3e-23
Identities = 80/287 (27%), Positives = 147/287 (50%), Gaps = 40/287 (13%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVM-EILNHPNIVQY 1323
+G G++G+V + L +KI D+++ + S+ +E R++ E+ P IVQ
Sbjct: 11 LGKGTYGSVELFSHKQNDGSLLYNAVKIMDSEN----YGSIDQEFRILSELRGCPCIVQL 66
Query: 1324 ------YGVEVHRDKVNIF-MEFCEGSSLASLLEHGRIE-DEMVTQVYTLQLLEGLACLH 1375
G++ + KV + ME+ +L + ++ R + + V + +T +L+GL +H
Sbjct: 67 CGNSLVQGIDCNGKKVYMMSMEYAAAGTLTNFIKRNRTKLSDSVIKDFTRMILQGLVSIH 126
Query: 1376 QSGVVHRDIKPENILL---------DRNGVIKYVDFGAAKLIA-KNGSKRISLDANNKST 1425
G VH D+KP+NILL + + +K DFG + K+G R+
Sbjct: 127 NHGYVHCDLKPDNILLFPLYDKDTWNCSYELKISDFGISTRAGDKSGCWRVD-------- 178
Query: 1426 GGKDMIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNE-WAIMYH 1484
+ +GT +YM+PE+V+ G + D+WSLGC+VL+M TG+RPW + + +++ +
Sbjct: 179 --EPWVGTSIYMSPESVS-DGTTVEKTLDLWSLGCIVLKMYTGKRPWLGFEKDVKSLLLN 235
Query: 1485 VAAGHLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWIS 1531
A +P+ + R F+ +C + +R +A ELLL P+++
Sbjct: 236 QKAPEIPE-----TLPCDARLFLEKCFSRKPEERGSASELLLHPFLT 277
>7298323 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 514
Score = 109 bits (273), Expect = 3e-23
Identities = 69/218 (31%), Positives = 110/218 (49%), Gaps = 21/218 (9%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHP 1318
W +G G++G V +N TG+ +A+K + D K S+++E+ + ++L
Sbjct: 22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMV---DLKKHPDAANSVRKEVCIQKMLQDK 78
Query: 1319 NIVQYYGVEVHRDKVNIFMEFCEGSSLASLL----EHGRIEDEMVTQVYTLQLLEGLACL 1374
+I++++G IF+E+ G L + + G + E Q Y QLL GL L
Sbjct: 79 HILRFFGKRSQGSVEYIFLEYAAGGELFDRIGEEPDVGMPQHE--AQRYFTQLLSGLNYL 136
Query: 1375 HQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
HQ G+ HRD+KPEN+LLD + +K DFG A + G +R+ LD GT
Sbjct: 137 HQRGIAHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERL-LDKR---------CGTL 186
Query: 1435 MYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW 1472
Y+APE + H + D+WS G +++ M+ G PW
Sbjct: 187 PYVAPEVLQKAYHAQ--PADLWSCGVILVTMLAGELPW 222
>7293496 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 805
Score = 109 bits (273), Expect = 3e-23
Identities = 80/275 (29%), Positives = 135/275 (49%), Gaps = 25/275 (9%)
Query: 1258 RWQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
R+ S +G GSFG VY A D ++A+K I + ++ K++ +L+ E + L H
Sbjct: 3 RYAVSSMVGQGSFGCVYKATRKDDSKVVAIKVIS-KRGRATKEL-KNLRRECDIQARLKH 60
Query: 1318 PNIVQYYGVEVHRDKVNIFM--EFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLH 1375
P++++ +E K ++F+ EF L +G + +E +V T L+ L LH
Sbjct: 61 PHVIEM--IESFESKTDLFVVTEFALMDLHRYLSYNGAMGEEPARRV-TGHLVSALYYLH 117
Query: 1376 QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
+ ++HRD+KP+N+LLD+N K DFG A+ + S+ GTP+
Sbjct: 118 SNRILHRDLKPQNVLLDKNMHAKLCDFGLARNMTLGTHVLTSIK------------GTPL 165
Query: 1436 YMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPT 1495
YMAPE + Q + D+WSLGC+ E + G+ P+ +I++ V
Sbjct: 166 YMAPELLAEQPYDHHA--DMWSLGCIAYESMAGQPPFC----ASSILHLVKMIKHEDVKW 219
Query: 1496 KSEISSAGRKFISRCLIQDANKRATAMELLLDPWI 1530
S ++S R F+ L +D R + +LL P++
Sbjct: 220 PSTLTSECRSFLQGLLEKDPGLRISWTQLLCHPFV 254
>SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 436
Score = 109 bits (272), Expect = 4e-23
Identities = 80/267 (29%), Positives = 133/267 (48%), Gaps = 27/267 (10%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIK----IQDAKSMKQIFPSLKEEMRVMEI 1314
+Q + +G GS+G V +TG + A K++K + AK ++Q K E +++E
Sbjct: 91 FQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQT----KNERQILEE 146
Query: 1315 LNHPNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACL 1374
+ HP I + Y D++ + +++ G L S L R+ E V YT +L L L
Sbjct: 147 VRHPFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELTLALIHL 206
Query: 1375 HQSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
H+ G+V+RD+KPEN LLD G I DFG +K +A+NG+ + +GT
Sbjct: 207 HKLGIVYRDLKPENCLLDAEGHILLTDFGLSK-VAENGA------------DCRSFVGTE 253
Query: 1435 MYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFP 1494
Y APE + Q + + D WS+G ++ +++TG P+ +N IM + P P
Sbjct: 254 EYCAPEILLEQPYDH--AVDWWSMGILIFDLLTGSPPF-TANNHKRIMEKITRAK-PNIP 309
Query: 1495 TKSEISSAGRKFISRCLIQDANKRATA 1521
++S R I++ L ++ +R A
Sbjct: 310 --FYVTSDARDIINKFLKKNPKQRLGA 334
>Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1036
Score = 109 bits (272), Expect = 4e-23
Identities = 74/250 (29%), Positives = 122/250 (48%), Gaps = 29/250 (11%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDI-LAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNH 1317
+ KR +G G+F V+ + D +A+K I ++ S QI L +E+++++ L H
Sbjct: 9 YSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNL-SKSQIL--LGKEIKILKELQH 65
Query: 1318 PNIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQS 1377
NIV Y V+ + V + ME+C G LA L+ E +V+ Q+ + LH
Sbjct: 66 ENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSK 125
Query: 1378 GVVHRDIKPENILLDR--------NGV-IKYVDFGAAKLIAKNGSKRISLDANNKSTGGK 1428
G++HRD+KP+NILL +G+ IK DFG A+ + N
Sbjct: 126 GIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSN-------------MMAA 172
Query: 1429 DMIGTPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPW-ANLDNEWAIMYHVAA 1487
+ G+PMYMAPE + Q + D+WS+G V+ + + G+ P+ AN + + Y
Sbjct: 173 TLCGSPMYMAPEVIMSQHYD--AKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNR 230
Query: 1488 GHLPQFPTKS 1497
+P P ++
Sbjct: 231 SLMPSIPRET 240
>Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neurofibromin
Length = 445
Score = 109 bits (272), Expect = 4e-23
Identities = 82/281 (29%), Positives = 134/281 (47%), Gaps = 32/281 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQD-AKSMKQIFPSLKEEMRVMEILNHPNIVQY 1323
IG+GS+G G IL KE+ ++ KQ+ S E+ ++ L HPNIV+Y
Sbjct: 14 IGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVS---EVNLLRELKHPNIVRY 70
Query: 1324 YGVEVHRDKVNIF--MEFCEGSSLASLLEHGR-----IEDEMVTQVYTLQLLEGLACLHQ 1376
Y + R ++ ME+CEG LAS++ G +++E V +V T L C +
Sbjct: 71 YDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHRR 130
Query: 1377 SG----VVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIG 1432
S V+HRD+KP N+ LD +K DFG A+++ N+ ++ K +G
Sbjct: 131 SDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARIL------------NHDTSFAKTFVG 178
Query: 1433 TPMYMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQ 1492
TP YM+PE + + + DIWSLGC++ E+ P+ + + + G +
Sbjct: 179 TPYYMSPEQMNRMSYNE--KSDIWSLGCLLYELCALMPPFTAFSQK-ELAGKIREGKFRR 235
Query: 1493 FPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWISQI 1533
P + S + I+R L R + E+L +P I+ +
Sbjct: 236 IPYR--YSDELNEIITRMLNLKDYHRPSVEEILENPLIADL 274
>At2g34290 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 265
Score = 109 bits (272), Expect = 4e-23
Identities = 92/279 (32%), Positives = 138/279 (48%), Gaps = 42/279 (15%)
Query: 1264 FIGSGSFGTV--YSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIV 1321
++G GSFG+V +S + L DAKS+ + F L + IV
Sbjct: 6 YLGEGSFGSVSLFSYKRRCDVETLYAAVKTSDDAKSLYEEFQILSK------FKGCSRIV 59
Query: 1322 QYYGVEVHR---DK----VNIFMEFCEGSSLASLLEH---GRIEDEMVTQVYTLQLLEGL 1371
Q YG V + DK I ME+ G SL+ ++ ++ D M+ + +T LLEGL
Sbjct: 60 QCYGSGVEQRLNDKGYVEYTIPMEYAAGGSLSDFMDRFNDKKLPDPMIRK-FTRMLLEGL 118
Query: 1372 ACLHQSGVVHRDIKPENILLDRNGV----IKYVDFGAAKLIAKNGSKRISLDANNKSTGG 1427
A +H+ G VH D+KPENIL+ V +K DFG +K ++G
Sbjct: 119 ATIHRHGYVHCDLKPENILVFPGSVCDLKLKISDFGLSK---RDGDTTWWHPL------- 168
Query: 1428 KDMIGTPMYMAPETVTGQGHGKFGSD-DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVA 1486
K GTP+YM+PE+++ HG+ G D+WSLGCVVLEM TG+RPW + + E + +
Sbjct: 169 KSYAGTPIYMSPESIS---HGEIGKGLDLWSLGCVVLEMYTGKRPWWHTNYE---LEDLM 222
Query: 1487 AGHLPQFPTKSEISSAGRKFISRCLIQDANKRATAMELL 1525
+ P FP + + F+ C + ++R A+ LL
Sbjct: 223 KCYEPLFP--PNLPCDAKLFLMTCFAPEPDERKDALTLL 259
>At2g05060 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 315
Score = 109 bits (272), Expect = 4e-23
Identities = 89/270 (32%), Positives = 132/270 (47%), Gaps = 35/270 (12%)
Query: 1267 SGSFGTVYSAVNLDTGDILA-VKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYYG 1325
SGS + LD + A VK I A S+ LKE + E IVQ YG
Sbjct: 25 SGSVSLIKYKSRLDGQTLYAAVKTSNIIHADSL------LKEFQILSEFKGCSRIVQCYG 78
Query: 1326 VEVHRD-------KVNIFMEFCEGSSLA---SLLEHGRIEDEMVTQVYTLQLLEGLACLH 1375
+V + I ME+ G SL S + ++ D ++ + +T +LEGLA +H
Sbjct: 79 TKVQETINEEGDVEFTIPMEYASGGSLRHFMSRFKDMKLPDALIRR-FTRMILEGLAVIH 137
Query: 1376 QSGVVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPM 1435
G VH D+KPENIL+ + +K DFG +K + G + L ++ GTP+
Sbjct: 138 GHGYVHCDLKPENILVFPSFELKISDFGLSK---REGDSKWWLPSH-------PFAGTPV 187
Query: 1436 YMAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPT 1495
YM+PE+++ G + G D+WSLGCVVLEM TG+RPW + + + + + G +P
Sbjct: 188 YMSPESIS-NGETRRGL-DLWSLGCVVLEMYTGKRPWWDKNYD---LGDLKKGSMPLI-- 240
Query: 1496 KSEISSAGRKFISRCLIQDANKRATAMELL 1525
+I + F+ C + NKR A LL
Sbjct: 241 SKDIPCDAKLFVMTCFASETNKRKNAFTLL 270
>At1g32320 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 305
Score = 109 bits (272), Expect = 4e-23
Identities = 82/274 (29%), Positives = 129/274 (46%), Gaps = 33/274 (12%)
Query: 1260 QKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPN 1319
+K S +G GS GTVY + T + A+K ++ + ++ E +++ +
Sbjct: 49 EKLSVLGQGSGGTVYKTRHRRTKTLYALKVLR-------PNLNTTVTVEADILKRIESSF 101
Query: 1320 IVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGV 1379
I++ Y V V + ME E SL L ++ E + ++L+GL L + G+
Sbjct: 102 IIKCYAVFVSLYDLCFVMELMEKGSLHDALLAQQVFSEPMVSSLANRILQGLRYLQKMGI 161
Query: 1380 VHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAP 1439
VH DIKP N+L+++ G +K DFGA++++A G GT YM+P
Sbjct: 162 VHGDIKPSNLLINKKGEVKIADFGASRIVA---------------GGDYGSNGTCAYMSP 206
Query: 1440 ETVTGQGHGKFGSD-----DIWSLGCVVLEMVTGRRPWANLDN--EWAIMY-HVAAGHLP 1491
E V + G FG + D+WSLG VVLE GR P + + +WA ++ +
Sbjct: 207 ERVDLEKWG-FGGEVGFAGDVWSLGVVVLECYIGRYPLTKVGDKPDWATLFCAICCNEKV 265
Query: 1492 QFPTKSEISSAGRKFISRCLIQDANKRATAMELL 1525
P + R F+ RCL +D KR T ELL
Sbjct: 266 DIPVSCSLEF--RDFVGRCLEKDWRKRDTVEELL 297
>Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase
Length = 292
Score = 109 bits (272), Expect = 4e-23
Identities = 80/290 (27%), Positives = 137/290 (46%), Gaps = 24/290 (8%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G GS+G V + G +K++ +++A S ++ + ++E +++ L HPNIV Y
Sbjct: 12 VGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRER--RAAEQEAQLLSQLKHPNIVTYK 69
Query: 1325 -GVEVHRDKVNIFMEFCEGSSLASLLEH--GRIEDEMVTQVYTLQLLEGLACLHQSGVVH 1381
E + I M FCEG L L+ G++ E + +Q+ L LH+ ++H
Sbjct: 70 ESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEKHILH 129
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
RD+K +N+ L R +IK D G A+++ N +IGTP YM+PE
Sbjct: 130 RDLKTQNVFLTRTNIIKVGDLGIARVL------------ENHCDMASTLIGTPYYMSPEL 177
Query: 1442 VTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISS 1501
+ + + D+W+LGC V EM T + + N + +++Y + G LP P + S
Sbjct: 178 FSNKPYNY--KSDVWALGCCVYEMATLKHAF-NAKDMNSLVYRIIEGKLPAMP--RDYSP 232
Query: 1502 AGRKFISRCLIQDANKRATAMELLLDPWISQIRNIAFGGNAESFNNETHN 1551
+ I L + +R + +L P+I R I+F A +N
Sbjct: 233 ELAELIRTMLSKRPEERPSVRSILRQPYIK--RQISFFLEATKIKTSKNN 280
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 108 bits (271), Expect = 5e-23
Identities = 84/273 (30%), Positives = 141/273 (50%), Gaps = 32/273 (11%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEI-KIQ-DAKSMKQIFPSLKEEMRVMEILNHPNIVQ 1322
IG G+F V A ++ TG +A+K I K Q + S++++F E+R+M+ILNHPNIV+
Sbjct: 62 IGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF----REVRIMKILNHPNIVK 117
Query: 1323 YYGVEVHRDKVNIFMEFCEGSSLAS-LLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVH 1381
+ V + + + ME+ G + L+ HGR++++ + Q++ + HQ +VH
Sbjct: 118 LFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFR-QIVSAVQYCHQKRIVH 176
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGK--DMIGTPMYMAP 1439
RD+K EN+LLD + IK DFG +N + GGK G+P Y AP
Sbjct: 177 RDLKAENLLLDADMNIKIADFGF---------------SNEFTVGGKLDTFCGSPPYAAP 221
Query: 1440 ETVTGQGHGKFGSD-DIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSE 1498
E G+ + G + D+WSLG ++ +V+G P+ N + V G ++
Sbjct: 222 ELFQGKKYD--GPEVDVWSLGVILYTLVSGSLPFDG-QNLKELRERVLRG---KYRIPFY 275
Query: 1499 ISSAGRKFISRCLIQDANKRATAMELLLDPWIS 1531
+S+ + R L+ + KR T +++ D WI+
Sbjct: 276 MSTDCENLLKRFLVLNPIKRGTLEQIMKDRWIN 308
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 108 bits (271), Expect = 5e-23
Identities = 80/233 (34%), Positives = 114/233 (48%), Gaps = 20/233 (8%)
Query: 1265 IGSGSFGTVY---SAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIV 1321
+G GSFG V+ D G + A+K +K K ++ K E ++ +NHP IV
Sbjct: 79 LGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRV--RTKMERDILVEVNHPFIV 136
Query: 1322 QYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVH 1381
+ + K+ + ++F G + + L + E + Y +L L LHQ G+V+
Sbjct: 137 KLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQLGIVY 196
Query: 1382 RDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPET 1441
RD+KPENILLD G IK DFG +K S+D K+ GT YMAPE
Sbjct: 197 RDLKPENILLDEIGHIKLTDFGLSK---------ESVDQEKKA---YSFCGTVEYMAPEV 244
Query: 1442 VTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLD-NEWAIMYHVAAGHLPQF 1493
V +GH + S D WS G ++ EM+TG P+ D NE M A +PQF
Sbjct: 245 VNRRGHSQ--SADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQF 295
Score = 74.7 bits (182), Expect = 1e-12
Identities = 78/284 (27%), Positives = 121/284 (42%), Gaps = 36/284 (12%)
Query: 1259 WQKRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHP 1318
++ + IG GS+ ++ T AVK I KS + PS + E+ +M HP
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIID----KSKRD--PSEEIEI-LMRYGQHP 478
Query: 1319 NIVQYYGVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSG 1378
NI+ V V + + +G L + + E + + + LH G
Sbjct: 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQG 538
Query: 1379 VVHRDIKPENIL-LDRNG---VIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTP 1434
VVHRD+KP NIL +D + I+ DFG AK + G ++ TP
Sbjct: 539 VVHRDLKPSNILYMDESASADSIRICDFGFAKQL----------------RGENGLLLTP 582
Query: 1435 MY----MAPETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEW--AIMYHVAAG 1488
Y +APE + QG+ + DIWSLG + M+ G P+AN N+ I+ + G
Sbjct: 583 CYTANFVAPEVLMQQGYD--AACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNG 640
Query: 1489 HLP-QFPTKSEISSAGRKFISRCLIQDANKRATAMELLLDPWIS 1531
IS + +S L D ++R TA ++L WI+
Sbjct: 641 KFSLSGGNWDNISDGAKDLLSHMLHMDPHQRYTAEQILKHSWIT 684
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 108 bits (271), Expect = 5e-23
Identities = 75/260 (28%), Positives = 129/260 (48%), Gaps = 24/260 (9%)
Query: 1265 IGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNIVQYY 1324
+G+G+FG V+ A+K + I D +KQ + E V++ ++HP +++ +
Sbjct: 55 VGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQE-QHVHNEKSVLKEVSHPFLIRLF 113
Query: 1325 GVEVHRDKVNIFMEFCEGSSLASLLEHGRIEDEMVTQVYTLQLLEGLACLHQSGVVHRDI 1384
+ + ME+ G L S L + Y+ +++ + LH +V+RD+
Sbjct: 114 WTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDL 173
Query: 1385 KPENILLDRNGVIKYVDFG-AAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMAPETVT 1443
KPENILLDR+G IK DFG A KL+ + + + GTP Y+APE +
Sbjct: 174 KPENILLDRDGHIKLTDFGFAKKLVDRTWT----------------LCGTPEYLAPEVIQ 217
Query: 1444 GQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLDNEWAIMYHVAAGHLPQFPTKSEISSAG 1503
+GHG+ + D W+LG ++ EM++G P+ + DN + I + AG + FP +
Sbjct: 218 SKGHGR--AVDWWALGILIFEMLSGFPPFFD-DNPFGIYQKILAGKI-DFPRHLDFHV-- 271
Query: 1504 RKFISRCLIQDANKRATAME 1523
+ I + L+ D +R M+
Sbjct: 272 KDLIKKLLVVDRTRRLGNMK 291
>Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 607
Score = 108 bits (271), Expect = 5e-23
Identities = 71/218 (32%), Positives = 105/218 (47%), Gaps = 19/218 (8%)
Query: 1261 KRSFIGSGSFGTVYSAVNLDTGDILAVKEIKIQDAKSMKQIFPSLKEEMRVMEILNHPNI 1320
K +G G F Y A + +TG AVK I Q + + E+ + L H +I
Sbjct: 25 KGRLLGKGGFARCYEATDTETGSAYAVKVIP-QSRVAKPHQREKILNEIELHRDLQHRHI 83
Query: 1321 VQYYGVEVHRDKVNIFMEFCEGSSLASLLE--HGRIEDEMVTQVYTLQLLEGLACLHQSG 1378
V++ D + IF+E C SLA + + H +E E+ + Y Q+L GL LHQ G
Sbjct: 84 VRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEV--RYYLRQILSGLKYLHQRG 141
Query: 1379 VVHRDIKPENILLDRNGVIKYVDFGAAKLIAKNGSKRISLDANNKSTGGKDMIGTPMYMA 1438
++HRD+K N + N +K DFG A + ++ K + GTP Y+A
Sbjct: 142 ILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRK------------KTICGTPNYVA 189
Query: 1439 PETVTGQGHGKFGSDDIWSLGCVVLEMVTGRRPWANLD 1476
PE + QGHG D+WSLGCV+ ++ G P+ D
Sbjct: 190 PEVLLRQGHGP--EADVWSLGCVMYTLLCGSPPFETAD 225
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.133 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,748,843
Number of Sequences: 60738
Number of extensions: 3487866
Number of successful extensions: 17001
Number of sequences better than 1.0e-05: 1766
Number of HSP's better than 0.0 without gapping: 341
Number of HSP's successfully gapped in prelim test: 1425
Number of HSP's that attempted gapping in prelim test: 12299
Number of HSP's gapped (non-prelim): 2299
length of query: 1551
length of database: 30,389,216
effective HSP length: 120
effective length of query: 1431
effective length of database: 23,100,656
effective search space: 33057038736
effective search space used: 33057038736
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)