ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2141 good H KOG2599 Coenzyme transport and metabolism Pyridoxal/pyridoxine/pyridoxamine kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII2141 762171 761260 -304
(304 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNR027w [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 298 5e-81
YEL029c [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 194 1e-49
Hs4505701 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 154 2e-37
SPCC18.10 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 153 3e-37
7294969 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 151 1e-36
CE28472 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 149 4e-36
SPAC6F6.11c [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 148 8e-36
At5g37850 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 148 8e-36
CE11322 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase 141 1e-33
>YNR027w [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 317
Score = 298 bits (764), Expect = 5e-81
Identities = 149/300 (49%), Positives = 202/300 (66%), Gaps = 6/300 (2%)
Query: 5 KKVLSIQSHVVHGYVGNKAATFPLQCKGWDVDALNTVQFSNHPAYGFLSGFKSRSEDLER 64
KKVLSIQSHV+HGYVGNKAATFPLQ +GWDVD LNTVQFSNH Y +GFK +E+L
Sbjct: 9 KKVLSIQSHVIHGYVGNKAATFPLQYRGWDVDVLNTVQFSNHSGYAHFTGFKCSTEELVD 68
Query: 65 IIQDGLLSGLKIHYDAVLTGYLPDTQGLKKIGALLVKLCNDDPSLKWILDPVLGDNGKLY 124
I++ GL+ L+I YDAVL+GYLP+ Q L+K+ ++ +LC ++KWILDPVLGDNG+LY
Sbjct: 69 IVEKGLIGSLRIKYDAVLSGYLPNVQALQKVAGIVGQLCEGSENVKWILDPVLGDNGRLY 128
Query: 125 VPEDTVDIYKQILKDGSVYLATPNQFELEVLTGTVIADLNSLKNALNKFHVLYPKVRYLV 184
V + V +Y+ IL++ ++LATPNQFE+E+L G I L+ K A FH YP+V +V
Sbjct: 129 VDRECVAVYQDILQNFKIFLATPNQFEMELLVGMSIRTLDDAKQAFKLFHKKYPRVSRIV 188
Query: 185 VTSVNWPSSADDDSFVSA---CTDFTEYWYFNIPKINAHFSGSGDLFSAIIMDLLLSSE- 240
VTS+ +D++V A C+ E +++ IPKINA FSGSGDL SA++ D LL
Sbjct: 189 VTSLELSEFLSNDTYVVAGFDCSASEEIFFYEIPKINAKFSGSGDLISAMLTDSLLGDRR 248
Query: 241 --TVELPLALNSALSLVDGVLRRTYDLTSKPAQSDDTPFKINDLKIIQCKDLFRSYPVPN 298
+ L +L L LV +L++TYDL D+ I DLK+IQC+D+ + +P+
Sbjct: 249 CTQLSLSASLGQVLWLVTSILQKTYDLNIAERGPQDSTIDIKDLKLIQCRDILKQDLIPS 308
>YEL029c [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 312
Score = 194 bits (493), Expect = 1e-49
Identities = 115/301 (38%), Positives = 172/301 (56%), Gaps = 17/301 (5%)
Query: 6 KVLSIQSHVVHGYVGNKAATFPLQCKGWDVDALNTVQFSNHPAYGF--LSGFKSRSEDLE 63
++L+ QSHVVHGYVGNKAATFPLQC GWDVD N+VQFSNH YG + G +R DL+
Sbjct: 3 RLLATQSHVVHGYVGNKAATFPLQCLGWDVDCCNSVQFSNHTGYGLDKVFGTITRETDLK 62
Query: 64 RIIQDGLLSGLKIHYDAVLTGYLPDTQGLKKIGALLVKLCNDDPSLKWILDPVLGDNGKL 123
++ GL Y A+L+GYLP+ ++ +G K +P + W++DPV+GD G+L
Sbjct: 63 ELL-SGLFDNFSQDYQALLSGYLPNKNSVRCMGTYYAKFKEANPEMIWLMDPVMGDEGQL 121
Query: 124 YVPEDTVDIYKQILKDGS--VYLATPNQFELEVLTGTVIADLNSLKNALNKFHVLYPKVR 181
YV ED + Y+++ V + TPNQFELE+L G I LK AL K H P
Sbjct: 122 YVSEDVIPEYRKLALSPKQLVDIITPNQFELEILYGGEIKTKEHLKKALKKLHQTIP--- 178
Query: 182 YLVVTSVNWPSSADDD-SFVSACTDFTEYWYFNIPKINAHFSGSGDLFSAIIMD---LLL 237
++VTS + D D + A + + +P I+++F+G GDLFSA+++D +L
Sbjct: 179 VIIVTSCDCKMFDDKDFIYCVASMEGKTPIVYRVPFIDSYFTGVGDLFSALLLDRVYKIL 238
Query: 238 SSETVELPL--ALNSALSLVDGVLRRTYDLTS---KPAQSDDTPFKINDLKIIQCKDLFR 292
S+ T L +N+ L+++ VL+ T S K K +L++I+ +D++
Sbjct: 239 SNPTTTLKFEDQVNNVLNVIQKVLKITRSYASGKMKAKMGSALEMKEMELRLIESRDIYE 298
Query: 293 S 293
+
Sbjct: 299 T 299
>Hs4505701 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 312
Score = 154 bits (388), Expect = 2e-37
Identities = 102/297 (34%), Positives = 158/297 (52%), Gaps = 19/297 (6%)
Query: 6 KVLSIQSHVVHGYVGNKAATFPLQCKGWDVDALNTVQFSNHPAYGFLSGFKSRSEDLERI 65
+VLSIQSHV+ GYVGN+AATFPLQ G+++DA+N+VQFSNH Y G S++L+ +
Sbjct: 6 RVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQEL 65
Query: 66 IQDGLLSGLKIHYDAVLTGYLPDTQGLKKIGALLVKLCNDDPSLKWILDPVLGD----NG 121
+ L+ + YD VLTGY D L + ++ +L +P L ++ DPVLGD G
Sbjct: 66 YEGLRLNNMN-KYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEG 124
Query: 122 KLYVPEDTVDIYKQILKDGSVYLATPNQFELEVLTGTVIADLNSLKNALNKFHVLYPKVR 181
+YVPED + +YK+ + + TPNQFE E+L+G I ++ H + P
Sbjct: 125 SMYVPEDLLPVYKEKVVP-LADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDT- 182
Query: 182 YLVVTSVNWPSSADDDSFV---------SACTDFTEYWYFNIPKINAHFSGSGDLFSAII 232
+V+TS + PS + + A + E +I K++A F G+GDLF+A++
Sbjct: 183 -VVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAML 241
Query: 233 MDLLLSSETVELPLALNSALSLVDGVLRRTYDLTSKPAQSDDTPFKIN-DLKIIQCK 288
+ L +A +S + VL+RT A P + +L+++Q K
Sbjct: 242 L-AWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSK 297
>SPCC18.10 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 340
Score = 153 bits (387), Expect = 3e-37
Identities = 85/238 (35%), Positives = 134/238 (55%), Gaps = 14/238 (5%)
Query: 2 VSGKKVLSIQSHVVHGYVGNKAATFPLQCKGWDVDALNTVQFSNHPAYGFLSGFKSRSED 61
+ K+VLSIQS V HGYVGN++ATFPLQ W+VD + TV FSNH YG G E+
Sbjct: 9 IGNKRVLSIQSSVSHGYVGNRSATFPLQLHEWEVDVVPTVHFSNHLGYGATRGSACIPEE 68
Query: 62 LERIIQDGLLSGLKIHYDAVLTGYLPDTQGLKKIGALLVKLCNDDPSLKWILDPVLGDNG 121
+ ++ + LL I YDA+LTG++P+ ++ I ++ D P + W+LDPV+GD G
Sbjct: 69 VHDLL-NALLQDNGIVYDAILTGFVPNHDIIQVIFDCVLAYKKDHPKVLWLLDPVMGDQG 127
Query: 122 KLYVPEDTVDIYKQILKDGSVYLATPNQFELEVLTGTVIADLNSLKNALNKFHVLYPKVR 181
K+YV + + YK ++ + TPN FE+E+LT VI K L K + LY ++
Sbjct: 128 KMYVDTNVISTYKAMIP--HAFAITPNAFEVEILTDIVIHTQMDAKRGLEKIYQLY-GIQ 184
Query: 182 YLVVTSVNWPSSADDDSFVSACTDFT------EYWYFNIPKINAHFSGSGDLFSAIIM 233
++TS ++ C ++ + + + P ++ F+G+GDLFS +++
Sbjct: 185 NAIITSF----EVEESPGTLFCMGYSCEHGKPQLFLYQFPSLSGVFTGTGDLFSGLLL 238
>7294969 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 494
Score = 151 bits (381), Expect = 1e-36
Identities = 105/292 (35%), Positives = 164/292 (55%), Gaps = 21/292 (7%)
Query: 5 KKVLSIQSHVVHGYVGNKAATFPLQCKGWDVDALNTVQFSNHPAYGFLSGFKSRSEDLER 64
K+VLSIQSHVVHGYVGNK AT+PLQ G+DVD LN+VQFSNH Y G S ++L
Sbjct: 10 KRVLSIQSHVVHGYVGNKVATYPLQLLGFDVDPLNSVQFSNHTGYKTFKGPVSNEKELAT 69
Query: 65 IIQDGLLSGLKIHYDAVLTGYLPDTQGLKKIGALLVKLCNDDPSLKWILDPVLGDNGKLY 124
I + + L Y +LTGY+ + L+++G +L KL +P L ++ DPV+GDNG+LY
Sbjct: 70 IFEGLEENELLPLYSHLLTGYIGNPLFLRQVGHILKKLRQANPGLVYVCDPVMGDNGQLY 129
Query: 125 VPEDTVDIYKQILKDGSVYLA---TPNQFELEVLTGTVIADLNSLKNALNKFHVLYPKVR 181
VP++ + +Y +D + LA TPNQFE+E+LT + ++ A+ FH ++
Sbjct: 130 VPKELLPVY----RDEIIPLADIITPNQFEVELLTEKEVRSEAAVWEAMEWFH--QRGIK 183
Query: 182 YLVVTSVNWPSSADDDSFVSACTDFTEYWYFNIPKINAH---FSGSGDLFSAIIMDLLLS 238
+V++S + +F+S +IPK F+G+GDLF+++ L S
Sbjct: 184 TVVISSSDLGQPGVLRAFLSQQNG--PRLAIDIPKQGGKDLVFTGTGDLFASLF--LAHS 239
Query: 239 SETVELPLALNSALSLVDGVLRRTYDLTSKPAQSDDTPFKI--NDLKIIQCK 288
+ ++ ++ + V++RT + S P + P K +LK++Q K
Sbjct: 240 HGSKDIANVFEKTIASLQAVIKRT--VASLP-NGGNGPVKAAERELKLVQSK 288
>CE28472 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 338
Score = 149 bits (377), Expect = 4e-36
Identities = 95/287 (33%), Positives = 159/287 (55%), Gaps = 8/287 (2%)
Query: 5 KKVLSIQSHVVHGYVGNKAATFPLQCKGWDVDALNTVQFSNHPAYGFLSGFKSRSEDLER 64
++VLSIQSHVVHGY GNK + FPLQ G++VD +N+VQFSNH Y + G K ++LE
Sbjct: 43 RRVLSIQSHVVHGYAGNKCSVFPLQLHGFEVDFINSVQFSNHAGYEHVKGQKLTEKELEE 102
Query: 65 IIQDGLLSGLKIHYDAVLTGYLPDTQGLKKIGALLVKLCNDDPSLKWILDPVLGDNGKLY 124
+ + L+ + +Y VLTGY + L+KI ++ L + + ++ DPV+GDNG+ Y
Sbjct: 103 LYEGLTLNNIN-NYTHVLTGYCGNVTFLQKIADVVKDLKKKNGNTTFVCDPVMGDNGRYY 161
Query: 125 VPEDTVDIYKQILKDGSVYLATPNQFELEVLTGTVIADLNSLKNALNKFHVLYPKVRYLV 184
P++ + +Y+ ++ + L TPN FEL LTG+ I A+N+ H V+ +V
Sbjct: 162 TPKELMPVYRDLIIPLADVL-TPNAFELGELTGSPIETEEDCLRAVNELHA--KGVKTVV 218
Query: 185 VTSVNWPSSADDDSFVSACTDFTEYWYFNIPKINAHFSGSGDLFSAIIMDLLLSSETVEL 244
VTS + ++ A + + F P++ F G+GD F+++++ + L ++
Sbjct: 219 VTSGVTGAQTNESLRCYASVKGSHVYRFTFPRLVGQFVGTGDTFTSLLV-VWLDELNGDV 277
Query: 245 PLALNSALSLVDGVLRRTYDLTSKPAQSDDTPFKINDLKIIQC-KDL 290
A+ L+ + ++R+T Q D + +L++IQ KDL
Sbjct: 278 SEAVKRVLASMQCLIRKTSSYAQ--LQVDTNSRAMCELRLIQSRKDL 322
>SPAC6F6.11c [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 309
Score = 148 bits (374), Expect = 8e-36
Identities = 95/279 (34%), Positives = 153/279 (54%), Gaps = 18/279 (6%)
Query: 1 MVSGKKVLSIQSHVVHGYVGNKAATFPLQCKGWDVDALNTVQFSNHPAYGFLSGFKSRSE 60
M + K++L+IQS V HGYVGN+AATFPLQ GWDVDA+ TV+ SNH Y + G R+
Sbjct: 1 MNTTKRILAIQSSVCHGYVGNRAATFPLQLLGWDVDAIPTVELSNHAGYPIVKG---RTL 57
Query: 61 DLERIIQ--DGLLSGLKIHYDAVLTGYLPDTQGLKKIGALLVKLCNDDPSLKWILDPVLG 118
E+I+ G+ + Y+ +LTGY +K I ++ + + + W+ DPVLG
Sbjct: 58 SAEQILDLYKGVSAANPSGYECLLTGYARGIGSVKAIMEIVRSVKSKNKKAFWVFDPVLG 117
Query: 119 DNGKLYVPEDTVDIYKQILKDGSVYLATPNQFELEVLTGTVIADLNSLKNALNKFHVLYP 178
DNG+LYV E + +Y+++L L TPN FE E+L+G I +++ + Y
Sbjct: 118 DNGRLYVEESIIPLYREMLPFAD--LITPNGFEAEILSGMRINSIDTAFKCVECLQQKY- 174
Query: 179 KVRYLVVTSVNWPSSADDDSFVSACTDFTEYWYFNIPKINAHFSGSGDLFSAII------ 232
KV +V++S + + + + +++ ++ IP I F G+GDLF+A++
Sbjct: 175 KVPRVVISSFVVEENGVEKLYCIGSSIYSKSFFVLIPVIPGIFRGTGDLFTALMAAHIAE 234
Query: 233 ----MDLLLSSETVELPLALNSALSLVDGVLRRTYDLTS 267
+ L S + +L ++ ALS V V+++T D S
Sbjct: 235 SPDCTESLASIKEDKLKKSVEMALSSVHEVIQKTADRIS 273
>At5g37850 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 309
Score = 148 bits (374), Expect = 8e-36
Identities = 108/294 (36%), Positives = 159/294 (53%), Gaps = 18/294 (6%)
Query: 6 KVLSIQSHVVHGYVGNKAATFPLQCKGWDVDALNTVQFSNHPAYGFLSGFKSRSEDLERI 65
+VLSIQSH V GYVGNK+A FPLQ G+DVD +N+VQFSNH Y G + L +
Sbjct: 17 RVLSIQSHTVQGYVGNKSAVFPLQLLGYDVDPINSVQFSNHTGYPTFKGQVLNGQQLCDL 76
Query: 66 IQDGLLSGLKIHYDAVLTGYLPDTQGLKKIGALLVKLCNDDPSLKWILDPVLGDNGKLYV 125
I +GL + + Y VLTGY+ L I ++ KL + +P+L ++ DPV+GD GKLYV
Sbjct: 77 I-EGLEANDLLFYTHVLTGYIGSVSFLDTILEVINKLRSVNPNLTYVCDPVMGDEGKLYV 135
Query: 126 PEDTVDIYKQILKDGSVYLATPNQFELEVLTGTVIADLNSLKNALNKFHVLYPKVRYLVV 185
PE+ V +Y++ + + L TPNQFE E LTG I + A H P +V+
Sbjct: 136 PEELVHVYREKVVPLASML-TPNQFEAEKLTGLRINSEEDGREACAILHAAGPS--KVVI 192
Query: 186 TSVN------WPSSADDDSFVSACTDFTEYWYFNIPKINAHFSGSGDLFSAIIMDLLLSS 239
TS+ S + + E + I KI A+F+G+GDL +A+++ +
Sbjct: 193 TSITIGGILLLIGSHQKEKGLK-----PEQFKILIHKIPAYFTGTGDLMTALLLG-WSNK 246
Query: 240 ETVELPLALNSALSLVDGVLRRTYDLTSKPAQSDDTPFKINDLKIIQCKDLFRS 293
L A A+S + +LRRT D K A D T + ++++IQ ++ R+
Sbjct: 247 YPDNLDKAAELAVSTLQALLRRTLD-DYKRAGYDPTSSSL-EIRLIQSQEDIRN 298
>CE11322 [H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase
Length = 348
Score = 141 bits (356), Expect = 1e-33
Identities = 95/297 (31%), Positives = 159/297 (52%), Gaps = 18/297 (6%)
Query: 5 KKVLSIQSHVVHGYVGNKAATFPLQCKGWDVDALNTVQFSNHPA----------YGFLSG 54
++VLSIQSHVVHGY GNK + FPLQ G++VD +N+VQFSNH Y + G
Sbjct: 43 RRVLSIQSHVVHGYAGNKCSVFPLQLHGFEVDFINSVQFSNHAGNIEYLTLPTRYEHVKG 102
Query: 55 FKSRSEDLERIIQDGLLSGLKIHYDAVLTGYLPDTQGLKKIGALLVKLCNDDPSLKWILD 114
K ++LE + + L+ + +Y VLTGY + L+KI ++ L + + ++ D
Sbjct: 103 QKLTEKELEELYEGLTLNNIN-NYTHVLTGYCGNVTFLQKIADVVKDLKKKNGNTTFVCD 161
Query: 115 PVLGDNGKLYVPEDTVDIYKQILKDGSVYLATPNQFELEVLTGTVIADLNSLKNALNKFH 174
PV+GDNG+ Y P++ + +Y+ ++ + L TPN FEL LTG+ I A+N+ H
Sbjct: 162 PVMGDNGRYYTPKELMPVYRDLIIPLADVL-TPNAFELGELTGSPIETEEDCLRAVNELH 220
Query: 175 VLYPKVRYLVVTSVNWPSSADDDSFVSACTDFTEYWYFNIPKINAHFSGSGDLFSAIIMD 234
V+ +VVTS + ++ A + + F P++ F G+GD F+++++
Sbjct: 221 A--KGVKTVVVTSGVTGAQTNESLRCYASVKGSHVYRFTFPRLVGQFVGTGDTFTSLLV- 277
Query: 235 LLLSSETVELPLALNSALSLVDGVLRRTYDLTSKPAQSDDTPFKINDLKIIQC-KDL 290
+ L ++ A+ L+ + ++R+T Q D + +L++IQ KDL
Sbjct: 278 VWLDELNGDVSEAVKRVLASMQCLIRKTSSYAQ--LQVDTNSRAMCELRLIQSRKDL 332
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.138 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,610,568
Number of Sequences: 60738
Number of extensions: 784438
Number of successful extensions: 1788
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1751
Number of HSP's gapped (non-prelim): 9
length of query: 304
length of database: 30,389,216
effective HSP length: 106
effective length of query: 198
effective length of database: 23,950,988
effective search space: 4742295624
effective search space used: 4742295624
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)