ORF      STATUS       Function Best COG  Functional category                                          Pathways and functional systems
r_klactIII2153  suspect: LH   U     KOG0771  Intracellular trafficking, secretion, and vesicular transport  Prolactin regulatory element-binding protein/Protein transport protein SEC12p

BLASTP 2.2.3 [May-13-2002]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= r_klactIII2153 762625  765498 958  
         (958 letters)

Database: KOG eukaryal database 04/03 
           60,738 sequences; 30,389,216 total letters

Searching..................................................done

Color Key for Alignment Scores:   


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

YNR026c [U] KOG0771 Prolactin regulatory element-binding protein...   397   e-110
YCR067c_1 [U] KOG0771 Prolactin regulatory element-binding prote...   355   1e-97

>YNR026c [U] KOG0771 Prolactin regulatory element-binding protein/Protein
           transport protein SEC12p
          Length = 471

 Score =  397 bits (1019), Expect = e-110
 Identities = 202/433 (46%), Positives = 284/433 (64%), Gaps = 7/433 (1%)

Query: 10  YNIGYPVYGAKFLDNSTLLVAXXXXXXXXXIPNKISALKVDFQKKKIVKRFR---ELSLD 66
           YN+GYP YGAKFL+N TLLVA         IPNK++ L+VD  K    ++F    E +L+
Sbjct: 8   YNVGYPAYGAKFLNNDTLLVAGGGGEGNNGIPNKLTVLRVDPTKDTEKEQFHILSEFALE 67

Query: 67  DNDDSPTTLDYANNVILIGCNEGSEKIKSGKGNNHLRKYVFH--NEHLKFVASIDLDGSS 124
           DNDDSPT +D +  +IL+GCNE S KI  GKGN HLRK+ +   N+ L+F+ S+D D S+
Sbjct: 68  DNDDSPTAIDASKGIILVGCNENSTKITQGKGNKHLRKFKYDKVNDQLEFLTSVDFDAST 127

Query: 125 KPEEYTKLTYLSPDASVAAIASSKVPTVICIVNPTNLRETYEVETGNDVKDLHFSPDGKV 184
             ++YTKL Y+S + +VAAIASSKVP ++ I++P++L E +E+ET  +VKDLHFS DGKV
Sbjct: 128 NADDYTKLVYISREGTVAAIASSKVPAIMRIIDPSDLTEKFEIETRGEVKDLHFSTDGKV 187

Query: 185 LSYITASTLEVMSVVTGNFIVRKTDFDSNWKMSKIRFIDQDNVIIAATLAKGTGVVLIKV 244
           ++YIT S+LEV+S VTG+ I RKTDFD NW +SKI FI  D V+IAA+L KG G+VL K+
Sbjct: 188 VAYITGSSLEVISTVTGSCIARKTDFDKNWSLSKINFIADDTVLIAASLKKGKGIVLTKI 247

Query: 245 SLKSGVAKIVKSKIITSKFKGVTSLDVDPSGNLVALAGNENSVVIVTLRNFRIVKFFKQV 304
           S+KSG   +++SK +T++FKG+TS+DVD  G L  LA N+NS+ +V L++  + K FKQ 
Sbjct: 248 SIKSGNTSVLRSKQVTNRFKGITSMDVDMKGELAVLASNDNSIALVKLKDLSMSKIFKQA 307

Query: 305 HNFAITRLVFSPDSKLLASVSAANTVHILKVAPNLATSRSLMESFLTFLTNSXXXXXXXX 364
           H+FAIT +  SPDS  +ASVSAANT+HI+K+  N A   S+ +    F TN         
Sbjct: 308 HSFAITEVTISPDSTYVASVSAANTIHIIKLPLNYANYTSMKQKISKFFTNFILIVLLSY 367

Query: 365 XXXXXHEHNLHLKALDFMQEKYKKYTEKNDSSDYFVLHEYPQQTTLIGVINTDSSTSGHS 424
                ++HNLH    ++ ++ +   T+++  S  +V+ E   QTTL G   T +S     
Sbjct: 368 ILQFSYKHNLHSMLFNYAKDNF--LTKRDTISSPYVVDEDLHQTTLFGNHGTKTSVPSVD 425

Query: 425 ESTTISFHSENTV 437
                  H  ++V
Sbjct: 426 SIKVHGVHETSSV 438


>YCR067c_1 [U] KOG0771 Prolactin regulatory element-binding protein/Protein
           transport protein SEC12p
          Length = 422

 Score =  355 bits (912), Expect = 1e-97
 Identities = 183/403 (45%), Positives = 265/403 (65%), Gaps = 8/403 (1%)

Query: 6   DSTIYNIGYPVYGAKFLDNSTLLVAXXXXXXXXXIPNKISALKVDFQKKKIVKRFRELSL 65
           +S  Y++GYP+YGAKF++  TLLVA          PNKI+ALKV+FQKKK ++RFRE++L
Sbjct: 4   NSANYDVGYPIYGAKFINEGTLLVAGGGGQFNSSFPNKITALKVNFQKKKHIRRFREITL 63

Query: 66  DDNDDSPTTLDYANNVILIGCNEGSEKIKSGKGNNHLRKYVFHNEHLKFVASIDLDGSSK 125
           D  DD+PT+LD  NN+IL+GCNE          N+HLRK+VF  EHLKFVASID + ++ 
Sbjct: 64  DSIDDAPTSLDCNNNLILVGCNELFNDSSMENVNHHLRKFVFEQEHLKFVASIDFNRTTD 123

Query: 126 PEEYTKLTYLSPDASVAAIASSKVPTVICIVNPTNLRETYEVETGNDVKDLHFSPDGKVL 185
           P  +TK  Y++  A+VAAIASS+VPTVI I++P NL E YE+ETG +V DLHF+P+G +L
Sbjct: 124 PSVFTKFVYINQRATVAAIASSEVPTVIRIIDPRNLTENYEIETGREVNDLHFAPNGILL 183

Query: 186 SYITASTLEVMSVVTGNFIVRKTDFDSNWKMSKIRFIDQDNVIIAATLAKGTGVVLIKVS 245
           SYIT+++LEV SV  GNF+ RKTDFD N  +S IRF++ + +++AA+L+   GV L+K+ 
Sbjct: 184 SYITSNSLEVASVRDGNFVARKTDFDKNLVLSNIRFLNDNTLLVAASLSNSDGVSLLKLG 243

Query: 246 LKSGVAKIVKSKIITSKFKGVTSLDVDPSGNLVALAGNENSVVIVTLRNFRIVKFFKQVH 305
           + S   KI+K+        G+TS+DV P+   VAL+ N+N V IV++   ++V+   +VH
Sbjct: 244 VSSKGVKILKTASFMFDLNGITSMDVSPNKKFVALSSNDNLVAIVSVEKLKLVQLVPRVH 303

Query: 306 NFAITRLVFSPDSKLLASVSAANTVHILKVAPNLATSRSLMESFLTFLTNSXXXXXXXXX 365
              IT++ FSPDS+ LAS S  NT+++LK++    TS S++ +   F  N          
Sbjct: 304 ESTITKVTFSPDSRYLASTSMGNTINVLKLS---GTSSSILRNIWKFFLNFVLLVVLAGA 360

Query: 366 XXXXHEHNLH----LKALDFMQEKYKKYTE-KNDSSDYFVLHE 403
               ++HN+H      A D  + K+K+ T     SS YF +++
Sbjct: 361 IQLGYKHNVHGFIYKHAHDIYKSKFKENTTIDQGSSSYFTIND 403


  Database: KOG eukaryal database 04/03
    Posted date:  Apr 14, 2003  1:07 PM
  Number of letters in database: 30,389,216
  Number of sequences in database:  60,738
  
Lambda     K      H
   0.307    0.125    0.327 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,899,252
Number of Sequences: 60738
Number of extensions: 1621182
Number of successful extensions: 5510
Number of sequences better than 1.0e-05: 2
Number of HSP's better than  0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 5504
Number of HSP's gapped (non-prelim): 3
length of query: 958
length of database: 30,389,216
effective HSP length: 116
effective length of query: 842
effective length of database: 23,343,608
effective search space: 19655317936
effective search space used: 19655317936
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)