ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2353 good O KOG1556 Posttranslational modification, protein turnover, chaperones 26S proteasome regulatory complex, subunit RPN8/PSMD7
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII2353 828109 829107 333
(333 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR261c [O] KOG1556 26S proteasome regulatory complex subunit RP... 474 e-134
SPCC1682.10 [O] KOG1556 26S proteasome regulatory complex subuni... 300 2e-81
Hs4506231 [O] KOG1556 26S proteasome regulatory complex subunit ... 286 4e-77
At5g05780 [O] KOG1556 26S proteasome regulatory complex subunit ... 278 1e-74
7291779 [O] KOG1556 26S proteasome regulatory complex subunit RP... 277 2e-74
At3g11270 [O] KOG1556 26S proteasome regulatory complex subunit ... 274 1e-73
CE18135 [O] KOG1556 26S proteasome regulatory complex subunit RP... 258 9e-69
ECU04g0420 [O] KOG1556 26S proteasome regulatory complex subunit... 140 3e-33
Hs4503519 [J] KOG2975 Translation initiation factor 3 subunit f ... 82 1e-15
Hs12728890 [J] KOG2975 Translation initiation factor 3 subunit f... 80 3e-15
Hs5803096 [OT] KOG3050 COP9 signalosome subunit CSN6 74 4e-13
Hs13994333 [J] KOG2975 Translation initiation factor 3 subunit f... 69 1e-11
7296825 [J] KOG2975 Translation initiation factor 3 subunit f (e... 67 3e-11
At4g26430 [OT] KOG3050 COP9 signalosome subunit CSN6 66 6e-11
7300881 [OT] KOG3050 COP9 signalosome subunit CSN6 66 8e-11
At5g56280 [OT] KOG3050 COP9 signalosome subunit CSN6 65 1e-10
7302177 [J] KOG2975 Translation initiation factor 3 subunit f (e... 63 5e-10
At2g39990 [J] KOG2975 Translation initiation factor 3 subunit f ... 62 2e-09
SPBC4C3.07 [J] KOG2975 Translation initiation factor 3 subunit f... 60 3e-09
CE00932 [J] KOG2975 Translation initiation factor 3 subunit f (e... 54 3e-07
CE28377 [OT] KOG3050 COP9 signalosome subunit CSN6 49 8e-06
>YOR261c [O] KOG1556 26S proteasome regulatory complex subunit RPN8/PSMD7
Length = 338
Score = 474 bits (1220), Expect = e-134
Identities = 231/326 (70%), Positives = 277/326 (84%), Gaps = 5/326 (1%)
Query: 1 MSVPYEQXXXXXXXXXXXXDHHQRTNTPENKRCLGVILGDSSTATVRITNSFALPFEEDE 60
MS+ +E+ DH++RT T ENKRC+GVILGD++++T+R+TNSFALPFEEDE
Sbjct: 1 MSLQHEKVTIAPLVLLSALDHYERTQTKENKRCVGVILGDANSSTIRVTNSFALPFEEDE 60
Query: 61 KNPDVWFLDHNYIETMNEMCKKINAKEKLIGWYHSGGKLRASDLKINELFKKYSTNNNPV 120
KN DVWFLDHNYIE MNEMCKKINAKEKLIGWYHSG KLRASDLKINELFKKY T NNP+
Sbjct: 61 KNSDVWFLDHNYIENMNEMCKKINAKEKLIGWYHSGPKLRASDLKINELFKKY-TQNNPL 119
Query: 121 LLILDVKQEDIGLPTNAYVAVEQIKDDGTSTERTFIHIPSTVEADEAEEIGVEHLLKDVR 180
LLI+DVKQ+ +GLPT+AYVA+EQ+KDDGTSTE+TF+H+P T+EA+EAEEIGVEHLL+DVR
Sbjct: 120 LLIVDVKQQGVGLPTDAYVAIEQVKDDGTSTEKTFLHLPCTIEAEEAEEIGVEHLLRDVR 179
Query: 181 DQAAAGLSIKLTNQLNSLRGLQRKLKDIVAYLEKVANNELPVNHIILGKLQDIFNLLPNL 240
DQAA GLSI+LTNQL SL+GLQ KLKD+V YL+KV N ELP+NH ILGKLQD+FNLLPNL
Sbjct: 180 DQAAGGLSIRLTNQLKSLKGLQSKLKDVVEYLDKVINKELPINHTILGKLQDVFNLLPNL 239
Query: 241 GTPDKDEMIGSSHVLDNVTNNLEKALTVKTNDELMIIYISNLVRAIVAFDNLIENKIQNK 300
GTPD DE+ +H N++NNL+KALTVKTNDELM+IYISNLVR+I+AFD+LIENKIQNK
Sbjct: 240 GTPDDDEIDVENHDRINISNNLQKALTVKTNDELMVIYISNLVRSIIAFDDLIENKIQNK 299
Query: 301 KLLEKHSKVEVEQKEDATNDGIPAES 326
K+ E+ V+ K+ +D +ES
Sbjct: 300 KIQEQ----RVKDKQSKVSDDSESES 321
>SPCC1682.10 [O] KOG1556 26S proteasome regulatory complex subunit RPN8/PSMD7
Length = 324
Score = 300 bits (768), Expect = 2e-81
Identities = 145/300 (48%), Positives = 215/300 (71%), Gaps = 9/300 (3%)
Query: 20 DHHQRTNTPENKRCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMNEM 79
D + R+ +R +G++LG ++ V + NS+A+PFEEDEKN VWFLDHN++E+MNEM
Sbjct: 29 DSYNRSAKGTKRRVVGILLGQNNGDVVNVANSYAIPFEEDEKNASVWFLDHNFMESMNEM 88
Query: 80 CKKINAKEKLIGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILDVKQEDIGLPTNAYV 139
KKINA EKL+GWYH+G +LR SDL+IN L KKY N PVL+I+DVK + +GLPTNAY
Sbjct: 89 FKKINANEKLVGWYHTGPQLRPSDLEINNLLKKYIPN--PVLVIIDVKPKSVGLPTNAYF 146
Query: 140 AVEQIKDDGTSTERTFIHIPSTVEADEAEEIGVEHLLKDVRDQAAAGLSIKLTNQLNSLR 199
A+++I+DDG+ + RTF+H+PS++EA+EAEEIGVEHLL+D RD + L+ ++T Q SL+
Sbjct: 147 AIDEIEDDGSKSSRTFVHLPSSIEAEEAEEIGVEHLLRDTRDASVGTLATRVTQQAQSLQ 206
Query: 200 GLQRKLKDIVAYLEKVANNELPVNHIILGKLQDIFNLLPNLGTPDKDEMIGSSHVLDNVT 259
GL ++L +I YL KV + +LP+NH IL +LQ +FNLLPN+ + + S L+
Sbjct: 207 GLGQRLTEIADYLRKVVDGQLPINHAILAELQSVFNLLPNIFSGP----VVSEQALE--- 259
Query: 260 NNLEKALTVKTNDELMIIYISNLVRAIVAFDNLIENKIQNKKLLEKHSKVEVEQKEDATN 319
+ ++A V +ND+LM IYIS++VRA++A +L+++ +K + ++ K V+ E + N
Sbjct: 260 SEAQRAFNVNSNDQLMSIYISSIVRAVIALHDLLDSLAASKAMEQQDIKPTVQNGEVSAN 319
>Hs4506231 [O] KOG1556 26S proteasome regulatory complex subunit RPN8/PSMD7
Length = 324
Score = 286 bits (731), Expect = 4e-77
Identities = 138/302 (45%), Positives = 206/302 (67%), Gaps = 20/302 (6%)
Query: 20 DHHQR-TNTPENKRCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMNE 78
DH R KR +GV+LG + ++NSFA+PF+ED+K+ VWFLDH+Y+E M
Sbjct: 21 DHFNRIVKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYG 80
Query: 79 MCKKINAKEKLIGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILDVKQEDIGLPTNAY 138
M KK+NA+E+++GWYH+G KL +D+ INEL K+Y N+ VL+I+DVK +D+GLPT AY
Sbjct: 81 MFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNS--VLVIIDVKPKDLGLPTEAY 138
Query: 139 VAVEQIKDDGTSTERTFIHIPSTVEADEAEEIGVEHLLKDVRDQAAAGLSIKLTNQLNSL 198
++VE+ +DDGT T +TF H+ S + A+EAEE+GVEHLL+D++D LS ++TNQ++ L
Sbjct: 139 ISVEEDQDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGL 198
Query: 199 RGLQRKLKDIVAYLEKVANNELPVNHIILGKLQDIFNLLPNLGTPDKDEMIGSSHVLDNV 258
+GL KL DI +YLEKV +LP+NH I+ +LQD+FNLLP++ +
Sbjct: 199 KGLNSKLLDIRSYLEKVGTGKLPINHQIIYQLQDVFNLLPDVSLQE-------------- 244
Query: 259 TNNLEKALTVKTNDELMIIYISNLVRAIVAFDNLIENKIQNKKLLEKHSKVEVEQKEDAT 318
KA +KTND+++++Y+++L+R++VA NLI NKI N+ +K + + E K+D
Sbjct: 245 ---FVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEKKEGQEKEESKKDRK 301
Query: 319 ND 320
D
Sbjct: 302 ED 303
>At5g05780 [O] KOG1556 26S proteasome regulatory complex subunit RPN8/PSMD7
Length = 308
Score = 278 bits (710), Expect = 1e-74
Identities = 141/308 (45%), Positives = 207/308 (66%), Gaps = 29/308 (9%)
Query: 20 DHHQRTNTPENKRCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMNEM 79
DH+ R +KR +GV+LG SS V +TNS+A+PFEED+K+P +WFLDHNY E+M M
Sbjct: 29 DHYNRVAKDSSKRVVGVLLGSSSRGVVDVTNSYAVPFEEDDKDPSIWFLDHNYHESMFHM 88
Query: 80 CKKINAKEKLIGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILDVKQEDIGLPTNAYV 139
K+INAKE ++GWY +G KLR +DL ++ LF Y NPVL+I+DV+ +++G+PT AY
Sbjct: 89 FKRINAKEHVVGWYSTGPKLRENDLDVHALFNGYVP--NPVLVIIDVQPKELGIPTKAYY 146
Query: 140 AVEQIKDDGT-STERTFIHIPSTVEADEAEEIGVEHLLKDVRDQAAAGLSIKLTNQLNSL 198
AVE++K++ T +++ F+H+ + + A E EEIGVEHLL+DV+D + L+ ++T +L +L
Sbjct: 147 AVEEVKENATQKSQKVFVHVSTEIAAHEVEEIGVEHLLRDVKDTTISTLATEVTAKLTAL 206
Query: 199 RGLQRKLKDIVAYLEKVANNELPVNHIILGKLQDIFNLLPNLGTPDKDEMIGSSHVLDNV 258
+GL +L++I +YL+ V +LP+NH IL LQD+FNLLPNL
Sbjct: 207 KGLDARLREIRSYLDLVIEGKLPLNHEILYHLQDVFNLLPNLN----------------- 249
Query: 259 TNNLEKALTVKTNDELMIIYISNLVRAIVAFDNLIENKIQNKKLLEKHSKVEVEQKEDAT 318
N L KA +VKTND +++IY+S+L+R+++A NLI NK+ NK E E+ ED+
Sbjct: 250 VNELVKAFSVKTNDMMLVIYLSSLIRSVIALHNLINNKLLNK---------EHEKAEDSK 300
Query: 319 NDGIPAES 326
IPA S
Sbjct: 301 PVAIPATS 308
>7291779 [O] KOG1556 26S proteasome regulatory complex subunit RPN8/PSMD7
Length = 338
Score = 277 bits (708), Expect = 2e-74
Identities = 137/304 (45%), Positives = 210/304 (69%), Gaps = 22/304 (7%)
Query: 20 DHHQRTNTPEN-KRCLGVILGD-SSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMN 77
DH R N KR +GV+LG S + ++NSFA+PF+ED+K+ VWFLDH+Y+E M
Sbjct: 23 DHFNRMGKIGNQKRVVGVLLGCWRSKGVLDVSNSFAVPFDEDDKDKSVWFLDHDYLENMY 82
Query: 78 EMCKKINAKEKLIGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILDVKQEDIGLPTNA 137
M KK+NA+E+++GWYH+G KL +D+ INEL ++Y N+ VL+I+D K +D+GLPT A
Sbjct: 83 GMFKKVNARERVVGWYHTGPKLHQNDIAINELVRRYCPNS--VLVIIDAKPKDLGLPTEA 140
Query: 138 YVAVEQIKDDGTSTERTFIHIPSTVEADEAEEIGVEHLLKDVRDQAAAGLSIKLTNQLNS 197
Y++VE++ DDG+ T +TF H+PS + A+EAEE+GVEHLL+D++D LS K+TNQL
Sbjct: 141 YISVEEVHDDGSPTSKTFEHVPSEIGAEEAEEVGVEHLLRDIKDTTVGSLSQKITNQLMG 200
Query: 198 LRGLQRKLKDIVAYLEKVANNELPVNHIILGKLQDIFNLLPNLGTPDKDEMIGSSHVLDN 257
L+GL +L+DI YL++V ++++P+NH I+ +LQDIFNLLP++ D+ G+ +
Sbjct: 201 LKGLNAQLRDIKQYLQRVGDSKMPINHQIVYQLQDIFNLLPDI---TNDQFTGTMY---- 253
Query: 258 VTNNLEKALTVKTNDELMIIYISNLVRAIVAFDNLIENKIQNKKLLE-KHSKVEVEQKED 316
VKTND+++++Y++++VR+I+A NLI NK+ N+ E K E ++K
Sbjct: 254 ----------VKTNDQMLVVYLASMVRSIIALHNLINNKLANRDAEEGKSDSKEAKEKNK 303
Query: 317 ATND 320
+ D
Sbjct: 304 DSKD 307
>At3g11270 [O] KOG1556 26S proteasome regulatory complex subunit RPN8/PSMD7
Length = 310
Score = 274 bits (701), Expect = 1e-73
Identities = 137/298 (45%), Positives = 202/298 (66%), Gaps = 24/298 (8%)
Query: 20 DHHQRTNTPENKRCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMNEM 79
DH+ R +KR +GV+LG SS TV +TNS+A+PFEED+K+ +WFLDHNY E+M M
Sbjct: 29 DHYNRVAKDTSKRVVGVLLGSSSRGTVDVTNSYAVPFEEDDKDTSIWFLDHNYHESMFHM 88
Query: 80 CKKINAKEKLIGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILDVKQEDIGLPTNAYV 139
K+INAKE ++GWY +G KLR +DL ++ LF Y NPVL+I+DV+ +++G+PT AY
Sbjct: 89 FKRINAKEHIVGWYSTGPKLRENDLDVHALFNGYVP--NPVLVIIDVQPKELGIPTKAYY 146
Query: 140 AVEQIKDDGT-STERTFIHIPSTVEADEAEEIGVEHLLKDVRDQAAAGLSIKLTNQLNSL 198
AVE++K++ T +++ F+H+P+ + A E EEIGVEHLL+DV+D + L+ ++T +L +L
Sbjct: 147 AVEEVKENATQKSQQVFVHVPTEIAAHEVEEIGVEHLLRDVKDTTISTLATEVTAKLTAL 206
Query: 199 RGLQRKLKDIVAYLEKVANNELPVNHIILGKLQDIFNLLPNLGTPDKDEMIGSSHVLDNV 258
+GL +L++I YL+ V +LP+NH IL LQD+FNLLPNL
Sbjct: 207 KGLDARLREIRTYLDLVIEGKLPLNHEILYHLQDVFNLLPNLN----------------- 249
Query: 259 TNNLEKALTVKTNDELMIIYISNLVRAIVAFDNLIENKIQNKKLLEKHSKVEVEQKED 316
N L KA VKTND +++IY+S+L+R+++A +LI NK+ NK +H K E + D
Sbjct: 250 VNELVKAFAVKTNDMMLVIYLSSLIRSVIALHSLINNKLLNK----EHEKAEDSKPVD 303
>CE18135 [O] KOG1556 26S proteasome regulatory complex subunit RPN8/PSMD7
Length = 362
Score = 258 bits (659), Expect = 9e-69
Identities = 132/299 (44%), Positives = 199/299 (66%), Gaps = 21/299 (7%)
Query: 20 DHHQRTNTPEN-KRCLGVILGD-SSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMN 77
DH R + ++ KR +GV+LG T+ I NSFA+PF+ED+K+ WFLD +Y+E+M
Sbjct: 53 DHFNRVSKTQSVKRVVGVLLGSMKKDKTLDIGNSFAVPFDEDDKDKSTWFLDMDYLESMY 112
Query: 78 EMCKKINAKEKLIGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILDVKQEDIGLPTNA 137
M K+ AKEK++GWYH+G KL +D+ INE K++ N PVL+I+D + ++IGLPT A
Sbjct: 113 GMFYKVAAKEKIVGWYHTGPKLHKNDIAINEQLKRFCPN--PVLVIIDAEPKNIGLPTEA 170
Query: 138 YVAVEQIKDDGTSTERTFIHIPSTVEADEAEEIGVEHLLKDVRDQAAAGLSIKLTNQLNS 197
Y+ V+++ DDGT +TF H+PS + A+EAEE+GVEHLL+D++DQ A LS ++T+QL
Sbjct: 171 YIEVQEVHDDGTPPIKTFEHVPSDIGAEEAEEVGVEHLLRDIKDQTAGTLSQRITDQLMG 230
Query: 198 LRGLQRKLKDIVAYLEKVANNELPVNHIILGKLQDIFNLLPNLGTPDKDEMIGSSHVLDN 257
LRGLQ +L+ I YL + LPVNH ++ +Q++ NLLP++ PD +++
Sbjct: 231 LRGLQSQLESIEKYLHDIVRGTLPVNHHVIYYVQEVLNLLPDVTHPD--------YIVSQ 282
Query: 258 VTNNLEKALTVKTNDELMIIYISNLVRAIVAFDNLIENKIQNKKLLEKHSKVEVEQKED 316
V+TND+LM +Y+ +LVR++VA NLI+NKI +K ++ E E+K+D
Sbjct: 283 ---------NVQTNDQLMCVYMGSLVRSVVALHNLIDNKISLQKAEKEQETGEAEKKKD 332
>ECU04g0420 [O] KOG1556 26S proteasome regulatory complex subunit RPN8/PSMD7
Length = 258
Score = 140 bits (353), Expect = 3e-33
Identities = 86/280 (30%), Positives = 147/280 (51%), Gaps = 44/280 (15%)
Query: 20 DHHQRTNTPENKRCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMNEM 79
DH++R T KR G++LGD + IT SFA FEEDE D WF+D +YI +M ++
Sbjct: 16 DHYKRKGT---KRVAGILLGDDD-GEIHITESFACIFEEDE---DGWFMDTSYIRSMFDL 68
Query: 80 CKKINAKEKLIGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILDVKQEDIGLPTNAYV 139
K+N K K++GWYH+G ++ +DL I + +P L I++V + LP +
Sbjct: 69 FYKVNHKLKVMGWYHTGPRMYENDLDITRSLGSFV--ESPFLAIINVHLGENDLPVQTFK 126
Query: 140 AVEQIKDDGTSTERTFIHIPSTVEADEAEEIGVEHLLKDVRDQAAAGLSIKLTNQLNSLR 199
EQ + F+H+ ++EA+EAEE+GVEHL++D+R++A+ ++ ++ SL
Sbjct: 127 LDEQDE---------FVHVGCSIEAEEAEEVGVEHLIRDIREEASGSIAARINGIKESLA 177
Query: 200 GLQRKLKDIVAYLEKVANNELPVNHIILGKLQDIFNLLPNLGTPDKDEMIGSSHVLDNVT 259
+ L +I +YL V + ++ +N I+ Q+I N P L P
Sbjct: 178 VYRGVLGEIRSYLNDVISGDIHLNQEIINLCQEIINSTPKLERP---------------- 221
Query: 260 NNLEKALTVKTNDELMIIYISNLVRAIVAFDNLIENKIQN 299
++ L Y+S L + +VA ++L +N++++
Sbjct: 222 ----------LDENLSDCYVSVLAKTVVALNDLRKNRLES 251
>Hs4503519 [J] KOG2975 Translation initiation factor 3 subunit f (eIF-3f)
Length = 357
Score = 81.6 bits (200), Expect = 1e-15
Identities = 65/277 (23%), Positives = 125/277 (44%), Gaps = 25/277 (9%)
Query: 20 DHHQRTNTPENKRCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMNEM 79
D ++R N R +G +LG +V +TN F++P E E D +D + + M E+
Sbjct: 104 DSYERRNEGA-ARVIGTLLGTVDKHSVEVTNCFSVPHNESE---DEVAVDMEFAKNMYEL 159
Query: 80 CKKINAKEKLIGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILDVKQEDIGLPTNAYV 139
KK++ E ++GWY +G + + I+E + + + NP+ L +D ++ + AYV
Sbjct: 160 HKKVSPNELILGWYATGHDITEHSVLIHEYYSREAP--NPIHLTVDTSLQNGRMSIKAYV 217
Query: 140 AVEQIKDDGTSTERTFIHIPSTVEADEAEEIGVEHLLKD-VRDQAAAGLSIKLTNQLNSL 198
+ + G + F + + E IGV+ ++K GLS L +
Sbjct: 218 ST-LMGVPGRTMGVMFTPLTVKYAYYDTERIGVDLIMKTCFSPNRVIGLSSDLQQVGGAS 276
Query: 199 RGLQRKLKDIVAYLEKVANNELPVNHIILGKLQDIFNLLPNLGTPDKDEMIGSSHVLDNV 258
+Q L ++ Y E V + ++ ++ + L + N +P + D + M+ S+
Sbjct: 277 ARIQDALSTVLQYAEDVLSGKVSADNTVGRFLMSLVNQVPKIVPDDFETMLNSN------ 330
Query: 259 TNNLEKALTVKTNDELMIIYISNLVRAIVAFDNLIEN 295
ND LM+ Y++NL ++ +A + + N
Sbjct: 331 -----------INDLLMVTYLANLTQSQIALNEKLVN 356
>Hs12728890 [J] KOG2975 Translation initiation factor 3 subunit f (eIF-3f)
Length = 361
Score = 80.5 bits (197), Expect = 3e-15
Identities = 65/277 (23%), Positives = 124/277 (44%), Gaps = 25/277 (9%)
Query: 20 DHHQRTNTPENKRCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMNEM 79
D ++R N R +G +LG +V +TN F++P E E D +D + + M E+
Sbjct: 108 DSYERRNEGA-ARVIGTLLGTVDKHSVEVTNCFSVPHNESE---DEVAVDMEFAKNMYEL 163
Query: 80 CKKINAKEKLIGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILDVKQEDIGLPTNAYV 139
KK++ E ++GWY +G + + I+E + + + NP+ L +D ++ + AYV
Sbjct: 164 HKKVSPNELILGWYATGHDITEHSVLIHEYYSREAP--NPIHLTVDTSLQNGRMSIKAYV 221
Query: 140 AVEQIKDDGTSTERTFIHIPSTVEADEAEEIGVEHLLKD-VRDQAAAGLSIKLTNQLNSL 198
+ + G + F + + E IGVE ++K GL L +
Sbjct: 222 ST-LMGVPGRTMGVMFTPLTVKYAYYDTERIGVELIMKTCFSPNRVIGLLSDLQQVGGAS 280
Query: 199 RGLQRKLKDIVAYLEKVANNELPVNHIILGKLQDIFNLLPNLGTPDKDEMIGSSHVLDNV 258
+Q L ++ Y E V + ++ ++ + L + N +P + D + M+ S+
Sbjct: 281 ARIQDALSTVLQYAEDVLSGKVSADNTVGRFLMSLVNRVPKIVPDDFETMLNSN------ 334
Query: 259 TNNLEKALTVKTNDELMIIYISNLVRAIVAFDNLIEN 295
ND LM+ Y++NL ++ +A + + N
Sbjct: 335 -----------INDLLMVTYLANLTQSQIALNEKLVN 360
>Hs5803096 [OT] KOG3050 COP9 signalosome subunit CSN6
Length = 297
Score = 73.6 bits (179), Expect = 4e-13
Identities = 57/227 (25%), Positives = 109/227 (47%), Gaps = 11/227 (4%)
Query: 20 DHHQRTNTPENK--RCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMN 77
DH R + E + + +G ++G + + NSF L E+ +D Y T
Sbjct: 23 DHWIRMRSQEGRPVQVIGALIGKQEGRNIEVMNSFELLSHTVEEKI---IIDKEYYYTKE 79
Query: 78 EMCKKINAKEKLIGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILDVKQEDIGLPTNA 137
E K++ + + +GWY +GG SD+ +++ + +P+ L L+ + LP +
Sbjct: 80 EQFKQVFKELEFLGWYTTGGPPDPSDIHVHK--QVCEIIESPLFLKLNPMTKHTDLPVSV 137
Query: 138 YVAVEQIKDDGTSTERTFIHIPSTVEADEAEEIGVEHLLKDVRDQAAAGLSI--KLTNQL 195
+ +V I +G +T F + T+ +EAE IGV+H+ + + ++ L Q
Sbjct: 138 FESVIDI-INGEAT-MLFAELTYTLATEEAERIGVDHVARMTATGSGENSTVAEHLIAQH 195
Query: 196 NSLRGLQRKLKDIVAYLEKVANNELPVNHIILGKLQDIFNLLPNLGT 242
++++ L ++K I+ Y++ E+P NH IL + + + LP L T
Sbjct: 196 SAIKMLHSRVKLILEYVKASEAGEVPFNHEILREAYALCHCLPVLST 242
>Hs13994333 [J] KOG2975 Translation initiation factor 3 subunit f (eIF-3f)
Length = 348
Score = 68.9 bits (167), Expect = 1e-11
Identities = 64/277 (23%), Positives = 125/277 (45%), Gaps = 34/277 (12%)
Query: 20 DHHQRTNTPENKRCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMNEM 79
D ++R N R +G +LG + +V +TN F++ + E D +D + + M E+
Sbjct: 94 DSYERRNKGA-ARVIGTLLGTVNKHSVEVTNCFSVSYNES----DEVVVDMEFAKNMYEL 148
Query: 80 CKKINAKEKLIGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILDVKQEDIGLPTNAYV 139
KK++ E ++GWY +G + + I+E + + + NP+ L +D ++ + AYV
Sbjct: 149 HKKVSPNELILGWYAAGHDITEHSVLIHEYYSREAP--NPIHLTVDTSLQNGHMSIKAYV 206
Query: 140 AVEQIKDDGTSTERTFIHIPSTVEAD--EAEEIGVEHLLKD-VRDQAAAGLSIKLTNQLN 196
+ G + P TV+ + E I V+ ++K GLS L
Sbjct: 207 STLM----GVPGRTVGVFTPLTVKYAYYDTECIRVDLIMKTCFSPNRVVGLSSDLQQVGG 262
Query: 197 SLRGLQRKLKDIVAYLEKVANNELPVNHII--LGK-LQDIFNLLPNLGTPDKDEMIGSSH 253
+ +Q L ++ Y E + + ++ ++ I +G L + N +P + D + M+ S+
Sbjct: 263 ASAHIQDALSIVLQYAEDILSAKVSADNTIRKVGHFLMSLVNQVPKIVPDDFETMLHSN- 321
Query: 254 VLDNVTNNLEKALTVKTNDELMIIYISNLVRAIVAFD 290
ND LM+ Y++NL ++ +A +
Sbjct: 322 ----------------INDLLMVAYLANLTQSQIALN 342
>7296825 [J] KOG2975 Translation initiation factor 3 subunit f (eIF-3f)
Length = 280
Score = 67.4 bits (163), Expect = 3e-11
Identities = 54/226 (23%), Positives = 106/226 (46%), Gaps = 12/226 (5%)
Query: 20 DHHQRTNTPENKRCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMNEM 79
D +R N ++ R +G +LG V +TN F +P +E + + + +Y M ++
Sbjct: 20 DAFERRNA-DSHRVIGTLLGSVDKGVVEVTNCFCVPHKEHDDQVEA---ELSYALDMYDL 75
Query: 80 CKKINAKEKLIGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILDVKQEDIGLPTNAYV 139
+K+N+ E ++GW+ +G + I+E + + NNPV L +D + + AYV
Sbjct: 76 NRKVNSNESVVGWWATGNDVTNHSSVIHEYYAREC--NNPVHLTVDTSLQGGRMGLRAYV 133
Query: 140 AVEQIKDDGTSTERTFIHIPSTVEADEAEEIGVEHLLKDVRDQAA-----AGLSIKLTNQ 194
+ Q+ G + F IP + + E E G++ L K V A + L
Sbjct: 134 CI-QLGVPGGKSGCMFTPIPVELTSYEPETFGLKLLQKTVGVSPAHRPKTVPPMLDLAQI 192
Query: 195 LNSLRGLQRKLKDIVAYLEKVANNELPVNHIILGKLQDIFNLLPNL 240
+ LQ L I+ Y++ V +++ ++ + +L D+ + +P++
Sbjct: 193 SEASTKLQSLLDLILKYVDDVIAHKVTPDNAVGRQLLDLIHSVPHM 238
>At4g26430 [OT] KOG3050 COP9 signalosome subunit CSN6
Length = 286
Score = 66.2 bits (160), Expect = 6e-11
Identities = 44/149 (29%), Positives = 72/149 (47%), Gaps = 11/149 (7%)
Query: 29 ENKRCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMNEMCKKINAKEK 88
+N R G ++G TV I NSF L F+ P + LD +++E E+ KK+
Sbjct: 54 QNPRVYGCVIGLQRGRTVEIFNSFELIFD-----PALDTLDRSFLEKKQELYKKVFPDFY 108
Query: 89 LIGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILD--VKQEDIGLPTNAYVAVEQIKD 146
++GWY +G SD+ I++ N +PV ++L+ + LP Y + + D
Sbjct: 109 VLGWYSTGSDATESDMHIHKAL--MDINESPVYVLLNPAINHAQKDLPVTIYESEFHVID 166
Query: 147 DGTSTERTFIHIPSTVEADEAEEIGVEHL 175
+ F+H T+E EAE I V+H+
Sbjct: 167 G--IPQSIFVHTSYTIETVEAERISVDHV 193
>7300881 [OT] KOG3050 COP9 signalosome subunit CSN6
Length = 341
Score = 65.9 bits (159), Expect = 8e-11
Identities = 52/223 (23%), Positives = 105/223 (46%), Gaps = 10/223 (4%)
Query: 24 RTNTPENKRCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMNEMCKKI 83
R E ++ G ++G + I NSF L + + D ++ +Y + K++
Sbjct: 72 RAQHGEPRQVYGALIGKQKGRNIEIMNSFEL---KTDVIGDETVINKDYYNKKEQQYKQV 128
Query: 84 NAKEKLIGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILDVKQEDIG-LPTNAYVAVE 142
+ IGWY +G A D+KI + N P++L L+ + LP + ++
Sbjct: 129 FSDLDFIGWYTTGDNPTADDIKIQRQIA--AINECPIMLQLNPLSRSVDHLPLKLFESLI 186
Query: 143 QIKDDGTSTERTFIHIPSTVEADEAEEIGVEHLLKDVRDQAA--AGLSIKLTNQLNSLRG 200
+ DG +T F+ + T+ +EAE IGV+H+ + +++ + ++ L Q ++++
Sbjct: 187 DLV-DGEAT-MLFVPLTYTLATEEAERIGVDHVARMTSNESGEKSVVAEHLVAQDSAIKM 244
Query: 201 LQRKLKDIVAYLEKVANNELPVNHIILGKLQDIFNLLPNLGTP 243
L ++K ++ Y+ V +L N IL + + + LP + P
Sbjct: 245 LNTRIKIVLQYIRDVEAGKLRANQEILREAYALCHRLPVMQVP 287
>At5g56280 [OT] KOG3050 COP9 signalosome subunit CSN6
Length = 286
Score = 65.5 bits (158), Expect = 1e-10
Identities = 43/149 (28%), Positives = 70/149 (46%), Gaps = 11/149 (7%)
Query: 29 ENKRCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMNEMCKKINAKEK 88
+N R G ++G TV I NSF L ++ P LD +++E E+ KK+
Sbjct: 54 QNPRVYGCVIGVQRGRTVEIFNSFELLYD-----PSTQTLDRSFLEKKQELYKKVFPDFY 108
Query: 89 LIGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILD--VKQEDIGLPTNAYVAVEQIKD 146
++GWY +G SD+ I++ N +PV ++L+ + LP Y + + D
Sbjct: 109 ILGWYSTGSDAEESDMHIHKAL--MDINESPVYVLLNPAINHTQKDLPVTIYESELHVID 166
Query: 147 DGTSTERTFIHIPSTVEADEAEEIGVEHL 175
+ F H T+E EAE I V+H+
Sbjct: 167 G--IPQLIFAHTSYTIETVEAERISVDHV 193
>7302177 [J] KOG2975 Translation initiation factor 3 subunit f (eIF-3f)
Length = 285
Score = 63.2 bits (152), Expect = 5e-10
Identities = 48/230 (20%), Positives = 108/230 (46%), Gaps = 6/230 (2%)
Query: 30 NKRCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETMNEMCKKINAKEKL 89
+ + +G +LG + + ITN F +P +E +N + LD Y + E+ E++
Sbjct: 32 DNQVMGTLLGRNKEGHIEITNCFTVPHKEHSENKRI-DLDMAYASEVLELNMFAYPNERV 90
Query: 90 IGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILDVKQEDIGLPTNAYVAVEQIKDDGT 149
+GW+ +G + S I++ + + P+ L++D ++ L T Y AVE GT
Sbjct: 91 LGWFCTGKSVSRSASLIHDYYVRECCEGQPLHLLVDAALKNQRLSTRLYCAVEMGVPGGT 150
Query: 150 STERTFIHIPSTVEADEAEEIGVEHLLKDVRDQAAAGLS---IKLTNQLNSLRGLQRKLK 206
F +P + + ++ + + + K + QA+ + +L +++ R +Q +L
Sbjct: 151 K-GLMFSLVPLEISNENSDLVALRCIEKQSQQQASKQMERFVPELAQVVDATRDMQHRLD 209
Query: 207 DIVAYLEKVANNELPVNHIILGKLQDIFNLLPNLGTPDKDEMIGSSHVLD 256
++ Y+ V + ++++ L +P L + DK ++ ++++ D
Sbjct: 210 LVLRYINDVLARKKKPDNVVGRSLYAALTAVPLLDS-DKFRVMFNTNLRD 258
>At2g39990 [J] KOG2975 Translation initiation factor 3 subunit f (eIF-3f)
Length = 293
Score = 61.6 bits (148), Expect = 2e-09
Identities = 62/259 (23%), Positives = 107/259 (40%), Gaps = 36/259 (13%)
Query: 31 KRCLGVILGDS-STATVRITNSFALPFEEDEKNPDVWFLDHNYIETMNEMCKKINAKEKL 89
+R +G +LG TV I NS+A+P E D +D +Y M K+N+KE +
Sbjct: 50 ERVIGTLLGSILPDGTVDIRNSYAVPHNESS---DQVAVDIDYHHNMLASHLKVNSKETI 106
Query: 90 IGWYHSGGKLRASDLKINELFKKYSTNNNPVLLILDVKQEDIGLPTNAYVAVEQIKDDGT 149
+GWY +G + I++ + + NP+ L +D + A+V+ D
Sbjct: 107 VGWYSTGAGVNGGSSLIHDFYAREVP--NPIHLTVDTGFTNGEGTIKAFVSSNLSLGDRQ 164
Query: 150 STERTFIHIPSTVEADEAEEIGVEHLLKDVRDQAAAGLSIKLTNQLNSLRGLQRKL---- 205
F IP + +AE +G + L D KL N L + +L
Sbjct: 165 LVAH-FQEIPVDLRMVDAERVGFDVLKATSVD--------KLPNDLEGMELTMERLLTLI 215
Query: 206 KDIVAYLEKVANNELPVNHIILGKLQDIFNLLPNLGTPDKDEMIGSSHVLDNVTNNLEKA 265
D+ Y++ V ++ ++ I + D LP L V DN+ N+
Sbjct: 216 NDVYKYVDSVVGGQIAPDNNIGRFIADAVASLPKL----------PPQVFDNLVND---- 261
Query: 266 LTVKTNDELMIIYISNLVR 284
D+L+++Y+S++ R
Sbjct: 262 ---SLQDQLLLLYLSSITR 277
>SPBC4C3.07 [J] KOG2975 Translation initiation factor 3 subunit f (eIF-3f)
Length = 302
Score = 60.5 bits (145), Expect = 3e-09
Identities = 63/277 (22%), Positives = 108/277 (38%), Gaps = 31/277 (11%)
Query: 22 HQRTNTPENKRCLGVILGDSST--ATVRITNSFALPFEEDEKNPDVWFLDHNYIETMNEM 79
H + N+R +G +LG S + I + FA+P E + +V + Y M +
Sbjct: 36 HSTRKSENNQRVIGTLLGTRSEDGREIEIKSCFAVPHNESSEQVEV---EMEYHRAMYHL 92
Query: 80 CKKINAKEKLIGWYHSGGKLRASDLKINELFKK--------YSTNNNPVLLILDVKQEDI 131
K N +E ++GWY + L A I L+ T +P + +
Sbjct: 93 HLKANPREVVVGWYATSPDLDAFSALIQNLYASPAEPGTAPLGTYPHPCVHLTVNTDVSS 152
Query: 132 GLPTNAYVAVEQIKDDGTSTERTFIHIPSTVEADEAEEIGVEHLLKDVRDQAA-AGLSIK 190
L YV+ + + F+ P T+ DEA G++ + D + A L
Sbjct: 153 PLAIKTYVSSPVGITERLADSCAFVPTPFTIRDDEAVRSGLKAVAAPKNDPSRLASLFTD 212
Query: 191 LTNQLNSLRGLQRKLKDIVAYLEKVANNELPVNHIILGKLQDIFNLLPNLGTPDKDEMIG 250
L S L ++ + Y++ V + P N + L F+L+P + D E I
Sbjct: 213 LQQLRRSTLELLSMIERVSDYVQNVIDGSSPANVAVGRYLMKCFSLIPCVEGQD-FEKIF 271
Query: 251 SSHVLDNVTNNLEKALTVKTNDELMIIYISNLVRAIV 287
SSH+ D L+++Y++N +R V
Sbjct: 272 SSHL----------------QDVLVVVYLANTLRTQV 292
>CE00932 [J] KOG2975 Translation initiation factor 3 subunit f (eIF-3f)
Length = 294
Score = 53.9 bits (128), Expect = 3e-07
Identities = 69/287 (24%), Positives = 123/287 (42%), Gaps = 48/287 (16%)
Query: 21 HHQRT-----NTPENKRCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIET 75
H +RT NT + K C+G ++G ++++TN FA+PF E + ++ D + +
Sbjct: 21 HMRRTKSSAKNTGQEK-CMGTLMGYYEKGSIQVTNCFAIPFNESNDDLEI---DDQFNQQ 76
Query: 76 MNEMCKKINAKEKLIGWYHSGGKLRASDLKINELFKKYST-----NNNPVLLILDVKQED 130
M KK + E+ +GW+ + + +S L ++ + + T +P +++L +
Sbjct: 77 MISALKKTSPNEQPVGWFLTTSDITSSCLIYHDYYVRVITEASARRESPPIVVLTIDTTF 136
Query: 131 IG-----LPTNAYVAVEQIKDDGTSTERTFIHIPSTVE--ADEAEEIGVEHLLK--DVRD 181
G +P AY+ + G + I P VE A E + ++ + K D R
Sbjct: 137 SGDMSKRMPVRAYLR-SKAGIPGAAGPHCAIFNPLRVELAAFPGELVAMQLIEKALDSRR 195
Query: 182 QAA---AGLSIKLTNQLNSLRGLQRKLKDIVAYLEKV-ANNELPVNHIILGKLQDIFNLL 237
+ A +GL T+ + L+R L Y+E V N E P + I +L DI
Sbjct: 196 REATLESGLEQLETSTAQMIEWLERMLH----YVEDVNKNGEKPGDAQIGRQLMDIVTAS 251
Query: 238 PNLGTPDKDEMIGSSHVLDNVTNNLEKALTVKTNDELMIIYISNLVR 284
N P+K LD + N D +M+ Y++ L +
Sbjct: 252 SNNMQPEK---------LDTLVKN-------TLRDYVMVSYLAKLTQ 282
>CE28377 [OT] KOG3050 COP9 signalosome subunit CSN6
Length = 426
Score = 49.3 bits (116), Expect = 8e-06
Identities = 57/221 (25%), Positives = 95/221 (42%), Gaps = 17/221 (7%)
Query: 20 DHHQRTNT---PENKRCLGVILGDSSTATVRITNSFALPFEEDEKNPDVWFLDHNYIETM 76
+H+ RT P K+ G ILG + V NSF L E +E V F + ++
Sbjct: 26 EHYSRTKVQQGPTVKKVFGAILGRQNGRQVEAINSFVLKMETEEMAEPVTFSTEHLLQRA 85
Query: 77 NEMCKKINAKEKLIGWYHSGGKLRASDLKINELFK-----KYSTNNNPVLLILDVKQEDI 131
++ ++ + ++IG Y +G + + L K + S + L +K I
Sbjct: 86 DQYL-EVFPELQVIGLYCAGEDDNLTPEEKPLLSKLTNAVRNSEKAGQIDATLFLKLNSI 144
Query: 132 GLPTNAYVAVEQIKDDGTSTERTFIHIPS--TVEADEAEEIGVEHLLKDVRDQAAAGLSI 189
T + + + D T E+ H P + ++E+E +GV H+ K G S+
Sbjct: 145 TAGTTRKLPLFAFEADVTDQEK---HKPIEWILVSEESERVGVNHIAKLSTKHGKDGKSV 201
Query: 190 KLTN---QLNSLRGLQRKLKDIVAYLEKVANNELPVNHIIL 227
+ Q ++ LQ ++ IVAYLEKV + L N IL
Sbjct: 202 GKKHAEAQDAAMSMLQNRVDLIVAYLEKVQDGTLQPNFEIL 242
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.312 0.132 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,465,384
Number of Sequences: 60738
Number of extensions: 844239
Number of successful extensions: 2119
Number of sequences better than 1.0e-05: 21
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2073
Number of HSP's gapped (non-prelim): 22
length of query: 333
length of database: 30,389,216
effective HSP length: 107
effective length of query: 226
effective length of database: 23,890,250
effective search space: 5399196500
effective search space used: 5399196500
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)