ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2405 good OPR KOG2195 General function prediction only Transferrin receptor and related proteins containing the protease-associated (PA) domain
r_klactIII2405 good OPR KOG2195 Inorganic ion transport and metabolism Transferrin receptor and related proteins containing the protease-associated (PA) domain
r_klactIII2405 good OPR KOG2195 Posttranslational modification, protein turnover, chaperones Transferrin receptor and related proteins containing the protease-associated (PA) domain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII2405 841867 844218 784
(784 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR256c [OPR] KOG2195 Transferrin receptor and related proteins ... 644 0.0
YPL176c [OPR] KOG2195 Transferrin receptor and related proteins ... 605 e-172
SPBC354.09c [OPR] KOG2195 Transferrin receptor and related prote... 177 7e-44
At5g19740 [OPR] KOG2195 Transferrin receptor and related protein... 149 2e-35
Hs4885505 [OPR] KOG2195 Transferrin receptor and related protein... 126 1e-28
Hs4758398 [OPR] KOG2195 Transferrin receptor and related protein... 124 4e-28
At3g54720 [OPR] KOG2195 Transferrin receptor and related protein... 124 6e-28
Hs4885507 [OPR] KOG2195 Transferrin receptor and related protein... 123 1e-27
Hs20480969 [OPR] KOG2195 Transferrin receptor and related protei... 119 2e-26
CE12844 [OPR] KOG2195 Transferrin receptor and related proteins ... 114 8e-25
CE08584 [OPR] KOG2195 Transferrin receptor and related proteins ... 102 3e-21
Hs4507455 [OPR] KOG2195 Transferrin receptor and related protein... 96 2e-19
Hs4507457 [OPR] KOG2195 Transferrin receptor and related protein... 87 8e-17
At4g07670 [OPR] KOG2195 Transferrin receptor and related protein... 74 1e-12
YJR126c [OPR] KOG2195 Transferrin receptor and related proteins ... 70 1e-11
>YOR256c [OPR] KOG2195 Transferrin receptor and related proteins containing
the protease-associated (PA) domain
Length = 809
Score = 644 bits (1660), Expect = 0.0
Identities = 344/780 (44%), Positives = 484/780 (61%), Gaps = 33/780 (4%)
Query: 20 PDVSSENVVDLDESLLPPNPPEYDIESRPDILPMELDIEQ-EDTISSVGRFQRLKTRIED 78
P S++N ++ + + PP PP Y E DIE D + QR+ ++
Sbjct: 38 PPSSNDNSIETNITP-PPEPPSY-----------EFDIEDPHDDLHKRTHLQRVSIGFQE 85
Query: 79 NLIFPMKNNVVDPLVQVYQMASAKVDLYLSKLGNPLILRRFVYILFMSVIVYTVVMSGLM 138
++ P+ N++ PL+Q+ + K D YLSK+GNP ILRRF YI+FMS I Y V+ SG +
Sbjct: 86 KILEPLMENIIHPLLQISKFVPDKADYYLSKIGNPFILRRFFYIIFMSFIAYYVLSSGYL 145
Query: 139 PNSKSTATIGMFSDKNQLIYYARRSIDYAKLEEDMEYLSSMPHLAGTKGDYAITNYIRES 198
N K++ + GMFS + L YA++S+D AK E D+EY+SSMPH +GTKGD AI YI+ES
Sbjct: 146 FNEKASGSKGMFSQHDILFEYAKKSVDLAKFERDLEYISSMPHGSGTKGDAAIYRYIQES 205
Query: 199 FKNNGLKLMKEVPFQGYMNFPNEVEFSVTTSDNKVHEFALSKENFNPLSSNGNIQNADII 258
F NNGLKL+KE+ + Y N+P V S + N+ H+ LSKENFNPLSSNG + +I
Sbjct: 206 FDNNGLKLVKEMGYSVYSNYPGNVSISYYDNKNEKHDLELSKENFNPLSSNGKLSKVSLI 265
Query: 259 YANYGTVADIQSLKENGLLSD--NTVLVMKYGNLPSEQILVAEKHGIKGIIFISKPFGND 316
Y GT D+Q LK++ + D + VL+++Y L S+Q+L+AEK G K +IFIS+P+G +
Sbjct: 266 YGGKGTTYDLQHLKDSKTIEDGKDYVLLLQYDKLVSQQVLIAEKFGAKAVIFISEPYGEN 325
Query: 317 GDVIQKLSVAIPQYGTGDALSPGWSTLSPKKIGLEKSQLVPHIPTIPISYNQGLKLKSIL 376
DV+Q V +PQY TGDA W SP + K HIPTIPIS QG +L S L
Sbjct: 326 IDVVQSKPVGLPQYSTGDASGLNWDG-SPVEEKDHKFWRQTHIPTIPISTRQGKELLSRL 384
Query: 377 NDGSPSIK--FEDSWFSGRKDDVKCNLRLANAEKTLQPSWNVLGKIEGKEQKDKAIIIAA 434
+ G ++ D SG+ DV ++ L + N++GKIEG+EQ DKAIIIAA
Sbjct: 385 SSGGVTVDDGNSDRSNSGKMGDVLIDVDLQTNVREKHFIPNIVGKIEGREQSDKAIIIAA 444
Query: 435 SHDSTCKGTLYPNFGTSSLMALLQLFQQTKYKYDWRPLRNIYFISYDGAQYNHVGATELM 494
S +S GT YPNFGT++L++++QLFQ+ KYK+ W+PLRNIYFIS+ G ++N+ G++EL+
Sbjct: 445 SRNSINFGTTYPNFGTAALLSIVQLFQEVKYKFGWKPLRNIYFISFGGTEFNYAGSSELV 504
Query: 495 ETEMNQLKSEVYAFIDISQLSV-------DPKARRALDVQATPLLQSLFKNTK--QFDVT 545
E + LK E+Y+ IDISQL + + K R L ++ PLL+ F FD++
Sbjct: 505 EQRLTPLKDEIYSLIDISQLGIPFAEKYENGKTRGELSIETHPLLKKFFNRNAHGNFDIS 564
Query: 546 VRNIAQYGDWTAYLANGIPTAVLSSPFVLNQTPPISTCSDDFQHWSEEIKGTEGAWEQVA 605
V N+ YGDWT +LANGIP +V+SS N+ P T D F+ E+I E + V
Sbjct: 565 VDNVQHYGDWTPFLANGIPVSVISSDSTRNRDTPTETSEDKFER-VEKILEDEQNQQSVK 623
Query: 606 DTLIYTYEMLLRLIDEPLLPFNVRDYVSNLDILFQDLQKQGGNNFDYASIQQGLKAWKKI 665
D L+Y + + LID+PLL F++ YV ++D Q L++ ++ SI +GL WKKI
Sbjct: 624 DLLVYLLHISMELIDDPLLHFDIISYVEDIDERLQRLEQAYPEKLNFTSIIKGLLFWKKI 683
Query: 666 SDEWNAWVHTWNNIVMMEDEGVEPSLVSVHRWTWNKKIMNIMKRQSLSSGIPDREFYKNV 725
EW +W W NIV +G+EPSL+S++RWTWNKK+ NI +R +G+P+R FYKNV
Sbjct: 684 GSEWASWTQGWENIVWSHGDGIEPSLLSINRWTWNKKLTNIGRRTCSPAGLPNRSFYKNV 743
Query: 726 LFGPTLWTQ---TNG--YDSWSFPGVRDALTSGNLKEAQKQINIAGNLLISSAQSFIDET 780
LFGPTL + NG D W+FPGV DA+ + K AQ+QI++ G +L SA F++ET
Sbjct: 744 LFGPTLIQEDKSKNGGNVDFWTFPGVMDAIYDDDWKRAQEQIDLIGKVLHQSAALFVEET 803
>YPL176c [OPR] KOG2195 Transferrin receptor and related proteins containing
the protease-associated (PA) domain
Length = 783
Score = 605 bits (1559), Expect = e-172
Identities = 300/739 (40%), Positives = 472/739 (63%), Gaps = 10/739 (1%)
Query: 46 SRPDILPMELDIEQEDTISSVG-RFQRLKTRIEDNLIFPMKNNVVDPLVQVYQMASAKVD 104
S P + E+ +E+ + + QR + E+N++ P+K NVVDPL Q+ +AS K D
Sbjct: 37 SEPPVYVEEMGMEEPQAPEAFSEKVQRFRMCFENNVVIPVKKNVVDPLAQMISLASEKFD 96
Query: 105 LYLSKLGNPLILRRFVYILFMSVIVYTVVMSGLMPNSKSTATIGMFSDKNQLIYYARRSI 164
L+LSK+GN +++RR YI+ MS+I ++ S +PN K+ + G FSD + L+ YAR+SI
Sbjct: 97 LFLSKIGNVMVMRRIFYIMMMSIIAALIIASDRLPNGKARGSNGSFSDHDLLLQYARKSI 156
Query: 165 DYAKLEEDMEYLSSMPHLAGTKGDYAITNYIRESFKNNGLKLMKEVPFQGYMNFPNEVEF 224
D +K+E D+EY+SSMPH++GT GD AI +YI+ESF NG++L E F Y N+P V
Sbjct: 157 DLSKIERDLEYISSMPHMSGTSGDAAIRHYIKESFDKNGIRLAGEEEFMAYSNYPGNVSL 216
Query: 225 SV-TTSDNKVHEFALSKENFNPLSSNGNIQNADIIYANYGTVADIQSLKENGLLSDNTVL 283
V + D + + L++ENFNP+S NG + N +IYAN ++ D+ S+++ GLL+ + +L
Sbjct: 217 RVYSKDDTEGFDIPLNEENFNPMSHNGQLNNIPVIYANKASLDDMASMQDQGLLNGDFIL 276
Query: 284 VMKYGNLPSEQILVAEKHGIKGIIFISKPFGNDGDVIQKLSVAIPQYGTGDALSPGWSTL 343
++ YG+ +Q+L A+++G K IIFIS+P+ ++ DVIQ SVA+PQYGTGDAL+P W
Sbjct: 277 LVHYGDYVFQQMLTAQEYGAKAIIFISEPYQDNKDVIQMKSVALPQYGTGDALTPEWEGS 336
Query: 344 SPKKIGLEKSQLVPHIPTIPISYNQGLKLKSILNDGSPSIKFEDSWFSGRKDDVKCNLRL 403
I +++ +P IP+IPIS NQG K+ +IL+D +KF ++ FSG +D + +L +
Sbjct: 337 IRDPIDATEAKCLPKIPSIPISANQGDKILAILSD--TGVKFSNNLFSGSLNDCRLDLLV 394
Query: 404 ANAEKTLQPSWNVLGKIEGKEQKDKAIIIAASHDSTCKGTLYPNFGTSSLMALLQLFQQT 463
A + P +++GKIEG EQ +AI+IAA +S GT+YP+FGT L++L+QL+Q+
Sbjct: 395 QTAIRERHPVHDIVGKIEGSEQAGRAIVIAAPRNSASYGTMYPSFGTVVLLSLIQLYQEM 454
Query: 464 KYKYDWRPLRNIYFISYDGAQYNHVGATELMETEMNQLKSEVYAFIDISQLSVDPKARRA 523
YK+DW+PLRNIYFIS+ G+++N GATELME LKSE+Y ID+ Q+ + +
Sbjct: 455 VYKFDWKPLRNIYFISFGGSEFNEAGATELMEKRTEALKSEIYTIIDVGQIGIWDDSNN- 513
Query: 524 LDVQATPLLQSLFK---NTKQFDVTVRNIAQYGDWTAYLANGIPTAVLSSPFVLNQTPPI 580
L++Q PLL LF+ +++F+V V N+ Q+GDWT YLA GIP A++SSP V+N+ PI
Sbjct: 514 LEIQCHPLLVDLFQKNMTSRKFNVKVDNVHQFGDWTPYLAQGIPVAIISSPGVMNREHPI 573
Query: 581 STCSDDFQHWSEEIKGTEGAWEQVADTLIYTYEMLLRLIDEPLLPFNVRDYVSNLDILFQ 640
T D F ++++ + E +++ ++Y E L LID+P +PF++ +YV L +
Sbjct: 574 YTVEDKFDFIKDKLRDKKKG-EVLSEIMLYLVEKSLELIDDPFIPFSISNYVDFLSTTLK 632
Query: 641 DLQKQGGNNFDYASIQQGLKAWKKISDEWNAWVHTWNNIVMMEDEGVEPSLVSVHRWTWN 700
DLQK+ + ++ + G W+ ++ W W ++ +EP++++++RW+WN
Sbjct: 633 DLQKECPDTVNFDEVFLGTTLWENTKLQFEKWKSEWTELMYGAGTYIEPTIIAINRWSWN 692
Query: 701 KKIMNIMKRQSLSSGIPDREFYKNVLFGPTLWT-QTNGYDSWSFPGVRDALTSGNLKEAQ 759
+ I Q L G+ DR FYKNV+FGP LW + + SW+FP +RD + + Q
Sbjct: 693 YLLSLIGVTQCLEEGLMDRTFYKNVIFGPKLWVDKGDPLRSWTFPEIRDTIAIKDWSSVQ 752
Query: 760 KQINIAGNLLISSAQSFID 778
Q N G +L ++A+ F++
Sbjct: 753 VQANTLGTILQNTARYFLE 771
>SPBC354.09c [OPR] KOG2195 Transferrin receptor and related proteins containing
the protease-associated (PA) domain
Length = 794
Score = 177 bits (448), Expect = 7e-44
Identities = 174/790 (22%), Positives = 343/790 (43%), Gaps = 87/790 (11%)
Query: 36 PPNPPEYD---IESRPDILPMELDIEQEDTISSVGRFQRLKTRIEDNLIFPMKNNVVDPL 92
P +PP Y+ + S + D EQ +T S+ + ++ ED+ FP+ + +
Sbjct: 12 PKDPPSYEEVALHSALNNSAPPNDGEQNET--SMEEMEIIEPPSEDSSRFPLLRTKLAAI 69
Query: 93 VQVYQMASAKVDLYLSKLGNPLILRRFVYILFMSVIVYTVVMSGLMPNSKSTATIGMFSD 152
+ ++ A ++ + + + + F+Y+ ++ ++ G + ++ + +
Sbjct: 70 HEGWESACHSFEIRFASTFHRIPFQ-FLYLAVIATVIILASYYGYFDGVPAWRSVHHYGE 128
Query: 153 KNQLIYYARRSIDYAKLEEDMEYLSSMPHLAGTKGDYAITNYIRESFKNNGLKLMKEVPF 212
L Y + D + + + LSS+PHLAGT GD ++ I ++ F
Sbjct: 129 DVLLNYI--KGCDISDTRQQVMTLSSIPHLAGTVGDSSLLQMIMNRLYYEKGTIVDFREF 186
Query: 213 QGYMNFPNEVEFSVTTSDNKVHEFALSKENFN---------PLSSNGN---IQNADIIYA 260
Y+NFP V S+ D+ H + P + G+ NA ++YA
Sbjct: 187 YAYLNFPQLVSLSID-GDDSFHPSLIESYQVGGYDGVSIPTPATFGGSPSGFVNAPLVYA 245
Query: 261 NYGTVADIQSLKENGLLSDNTVLVMKYGNLPSEQILV---AEKHGIKGIIFISKPFGNDG 317
N G + D + L +G+ ++++++++ S+ L AEK+ I+ +
Sbjct: 246 NRGRIEDFEWLVNSGIYVESSIVLVRANQ--SDFALATANAEKYNASAILIFEDTYLTSL 303
Query: 318 DVIQKL---------------SVAIPQYGTGDALSPGWSTLSP-KKIGLEKSQLVPHIPT 361
D + ++ SVA Y GD L+PGWS +I + + ++P I +
Sbjct: 304 DNLNQVYPAGPYPSANSLYRGSVANHYYYVGDPLTPGWSAHEETNRISPKDANVLPSIVS 363
Query: 362 IPISYNQGLKLKSILNDGSPSIK-----------FEDSWFSGRKDDVKCNLRLANAEKTL 410
IPI++N G++L L +K + W + + + +
Sbjct: 364 IPITFNDGIELLKRLQGHGHLVKDSNWCQDLAPVLSEVWTGSKISSPGLEVNVLQDIEDK 423
Query: 411 QPSWNVLGKIEGKEQKDKAIIIAASHDSTCKGTLYPNFGTSSLMALLQLFQQTKYKYDWR 470
Q N++ +I+G E D+ +++ A DS C G + GTS L+ ++ F W+
Sbjct: 424 QKIINIMAQIDGYES-DQILVVGAPRDSWCTGASDSSVGTSLLIDVISTFANMAQDLSWK 482
Query: 471 PLRNIYFISYDGAQYNHVGATELMETEMNQLKSEVYAFIDIS-QLSVDPKARRALDVQAT 529
P R I F S+D Q+N +G+TE +E L+++ A+I++ +S D R +
Sbjct: 483 PRRTIVFASWDARQFNAIGSTEFLEYWKESLEAKAVAYINVDVAVSGDTFTARTVPGLKK 542
Query: 530 PLLQSLFKNTKQFDVTVRNIA-----QYGDWTAYLA-NGIPTAVLSSPFVLNQTPP---- 579
+ ++ ++ ++ NI D T++L GIP V++ F N+ P
Sbjct: 543 VIQRAFDVANEEDEMKAANIITDDFDYTSDLTSFLTFAGIP--VVNLAFERNEENPTPMP 600
Query: 580 -ISTCSDDFQHWSEEIKGTEGAWEQVADT-LIYTYEMLLRLIDEPLLPFNVRDYVSNLDI 637
+ +C D W + G+E WE A I++Y ++L L ++P++P+++ D ++ +
Sbjct: 601 FLGSCEDTVS-WIDTF-GSE-YWENAARLGKIWSY-LILFLANDPVVPYDLEDEINGVGE 656
Query: 638 LFQDLQK-QGGNNFDYASIQQGLKAWKKISDEWNAWVHTWNNIVMMEDEGV----EPSLV 692
+ + + + G N D I + + + + W +++M V P L
Sbjct: 657 MLKRIPEIPGANALDLRKINEEFSELLESLIRFEDEIREWKSLMMHNSYTVSVKKHPELE 716
Query: 693 SVHRWTWNKKIMNIMKRQSLSSGIPDREFYKNVLFGPTLWTQTNGYDSWSFPGVRDALTS 752
+N K+ + +G+P E+YK++++GP L S FP + DAL
Sbjct: 717 G-----YNAKLARFERSFLDEAGLPGHEWYKHLIYGPNL----RNSHSQLFPSIFDALLY 767
Query: 753 GNLKEAQKQI 762
G+++ AQK++
Sbjct: 768 GDVEAAQKEV 777
>At5g19740 [OPR] KOG2195 Transferrin receptor and related proteins containing
the protease-associated (PA) domain
Length = 670
Score = 149 bits (376), Expect = 2e-35
Identities = 163/639 (25%), Positives = 276/639 (42%), Gaps = 100/639 (15%)
Query: 165 DYAKLEEDMEYLSSMPHLAGTKGDYAITNYIRESFKNNGLKLMKEVPFQGYMNFPNEVEF 224
D A + ++ L+ PH+AGT + Y+R F ++ LK V +Q + +P
Sbjct: 41 DNASVALNLHTLTRRPHVAGTVANAEAAEYVRSVFTSSALK-SHVVAYQVSLTYPVHRSL 99
Query: 225 SVTTSDN-KVHEFALSKEN-------------FNPLSSNGNIQNADIIYANYGTVADIQS 270
+T +D+ K F L +E F+ + +GN+ + ++YANYG V D
Sbjct: 100 VLTPTDSAKPITFLLEQEKLGDNPYANEVMPTFHGYAKSGNV-SGPVVYANYGRVEDFVR 158
Query: 271 LKEN-GLLSDNTVLVMKYGNLPSEQILV-AEKHGIKGIIFISKPFGNDGDVIQKLSVAIP 328
LK++ G+ V++ +YG + I+ A + G G++ + GD S +P
Sbjct: 159 LKKDMGVNVSGAVVIARYGQIYRGDIVKNAYEAGAVGVVIYTDKRDYGGDEWFPASKWMP 218
Query: 329 ----QYGT-----GDALSPGWSTLSP----KKIGLEKSQLVPHIPTIPISYNQG-LKLKS 374
Q GT GD +PGW+++ +E S VP IP++P+S + LK+
Sbjct: 219 PSGVQVGTVYNGLGDPTTPGWASVDGCERLSDEAVELSGDVPLIPSLPVSAADAEVILKT 278
Query: 375 ILNDGSPSIKFEDSWFSGRKDDVKCNLRLANAEKTLQPSWNVLGKIEGKEQKDKAIIIAA 434
++ D S + G E + NV+G IEG+E+ D+ +I+
Sbjct: 279 VVGDVSDGDVYPVGPGPG-------------GETVIAKIENVIGVIEGEEEPDRYVILGN 325
Query: 435 SHDSTCKGTLYPNFGTSSLMALLQLFQQTKYKYDWRPLRNIYFISYDGAQYNHVGATELM 494
D+ G + PN GT+ L +L K W+P R I ++D +Y +G+TE +
Sbjct: 326 HRDAWTFGAVDPNSGTAIAQRLDKL-----QKRGWKPRRTIILCNWDAEEYGLIGSTEWV 380
Query: 495 ETEMNQLKSEVYAFIDISQLSVDPKARRALDVQATPLLQSLFKNTKQ------------- 541
E L S A++++ P ATP L L K Q
Sbjct: 381 EENREMLSSRAVAYLNVDCAVSGP----GFHASATPQLDELIKVAAQEVRDPDNATQTIY 436
Query: 542 -------FDVTVRNIAQYG-DWTAYLAN-GIPTAVLSSPFVLNQTPPISTCSDDFQHWSE 592
V +R + G D+ +++ + G+P +S P + DDF W E
Sbjct: 437 ESWIGSSDSVVIRRLGGGGSDYASFVQHVGVPGVDMSFG---RGYPVYHSMYDDFT-WME 492
Query: 593 EIKGTEGAWEQVADTLIYTYEMLLRLIDEPLLPFNVRDYVSNLDILFQDLQKQG-GNNFD 651
+ G VA + + LRL DE ++PFN Y L +DL+ + G+N D
Sbjct: 493 KF-GDPMFQRHVAMASVLGL-VALRLADEEIIPFNYTSYALELKKSAEDLENEKLGHNID 550
Query: 652 YASIQQGLKAWKKISDEWNAWVHTWNNIVMMEDEGVEPSLVSVHRWTWNKKIMNIMKRQS 711
+++ K I D A H + +E E ++ +L N ++M + +
Sbjct: 551 VSTL------IKSIEDLSTAAKH-----ISLEKEAIKGALKVRE---LNDRLMMAERALT 596
Query: 712 LSSGIPDREFYKNVLFGPTLWTQTNGYDSWSFPGVRDAL 750
G+ +R +YK++++GP+ + + Y S SFPGV DA+
Sbjct: 597 DRDGLSERPWYKHLIYGPSKY---DDYGSKSFPGVDDAI 632
>Hs4885505 [OPR] KOG2195 Transferrin receptor and related proteins containing
the protease-associated (PA) domain
Length = 740
Score = 126 bits (317), Expect = 1e-28
Identities = 161/698 (23%), Positives = 288/698 (41%), Gaps = 133/698 (19%)
Query: 177 SSMPHLAGTKGDYAITNYIRESFKNNGLKLMKEVPFQGYMNFPNEVEFSVTTSDNKVHEF 236
+ +PHLAGT+ ++ + I+ +K GL K V + +++PNE + + ++ HE
Sbjct: 68 TKLPHLAGTEQNFLLAKKIQTQWKKFGLDSAKLVHYDVLLSYPNETNANYISIVDE-HET 126
Query: 237 ALSKEN------------------FNPLSSNGNIQNADIIYANYGTVADIQSL-KENGLL 277
+ K + +N S+ G + D++Y NY D L +E G+
Sbjct: 127 EIFKTSYLEPPPDGYENVTNIVPPYNAFSAQG-MPEGDLVYVNYARTEDFFKLEREMGIN 185
Query: 278 SDNTVLVMKYGNL-PSEQILVAEKHGIKGIIFISKP--------------FGNDGDVIQK 322
+++ +YG + ++ A G GII S P + G Q+
Sbjct: 186 CTGKIVIARYGKIFRGNKVKNAMLAGAIGIILYSDPADYFAPEVQPYPKGWNLPGTAAQR 245
Query: 323 LSVAIPQYGTGDALSPGWSTLS-PKKIGLEKSQLVPHIPTIPISYNQGLKLKSILNDGSP 381
+V + G GD L+PG+ ++ +E+ +P IP PI YN L L +P
Sbjct: 246 GNV-LNLNGAGDPLTPGYPAKEYTFRLDVEEGVGIPRIPVHPIGYNDAEILLRYLGGIAP 304
Query: 382 SIKFEDSW-------------FSGRKDDVKCNLRLANAEKTLQPSWNVLGKIEGKEQKDK 428
K SW F+G K + + N K + +NV+G I G + D+
Sbjct: 305 PDK---SWKGALNVSYSIGPGFTGSDSFRKVRMHVYNINK-ITRIYNVVGTIRGSVEPDR 360
Query: 429 AIIIAASHDSTCKGTLYPNFGTSSLMALLQLFQQTKYKYDWRPLRNIYFISYDGAQYNHV 488
+I+ DS G + P G + L + + F + K WRP R I F S+D ++ +
Sbjct: 361 YVILGGHRDSWVFGAIDPTSGVAVLQEIARSFGKLMSK-GWRPRRTIIFASWDAEEFGLL 419
Query: 489 GATELMETEMNQLKSEVYAFIDISQLSVDPKARRALDVQATPLL-QSLFKNTKQF---DV 544
G+TE E + L+ A+I+ S S++ L V TPLL Q ++K TK+ D
Sbjct: 420 GSTEWAEENVKILQERSIAYIN-SDSSIE--GNYTLRVDCTPLLYQLVYKLTKEIPSPDD 476
Query: 545 TVRNIAQYGDWTAYLANGIPTAVLSSPFVLNQTPPISTCSDDFQ---------HWSEEIK 595
+ + Y W P+ + +N+ S FQ +++ K
Sbjct: 477 GFESKSLYESW----LEKDPSPENKNLPRINKLGSGSDFEAYFQRLGIASGRARYTKNKK 532
Query: 596 GTEGAWEQVADTLIYTYE----------------------MLLRLIDEPLLPFNVRDY-- 631
+ + V T+ T+E ++ L+D ++PFN++DY
Sbjct: 533 TDKYSSYPVYHTIYETFELVEKFYDPTFKKQLSVAQLRGALVYELVDSKIIPFNIQDYAE 592
Query: 632 --------VSNLDILFQDLQKQGGNNFDYASIQQGLKAWKKISDEWNAWVHTWNNIVMME 683
+ NL G +FD S+ +K + + + +++ +++
Sbjct: 593 ALKNYAASIYNLSKKHDQQLTDHGVSFD--SLFSAVKNFSEAASDFHK--------RLIQ 642
Query: 684 DEGVEPSLVSVHRWTWNKKIMNIMKRQSLSSGIPDREFYKNVLFGPTLWTQTNGYDSWSF 743
+ P V + N ++M + + G+P + FY++++F P + N Y SF
Sbjct: 643 VDLNNPIAVRM----MNDQLMLLERAFIDPLGLPGKLFYRHIIFAP---SSHNKYAGESF 695
Query: 744 PGVRDAL------TSGNL--KEAQKQINIAGNLLISSA 773
PG+ DA+ + L KE +K I+IA + ++A
Sbjct: 696 PGIYDAIFDIENKANSRLAWKEVKKHISIAAFTIQAAA 733
>Hs4758398 [OPR] KOG2195 Transferrin receptor and related proteins containing
the protease-associated (PA) domain
Length = 750
Score = 124 bits (312), Expect = 4e-28
Identities = 161/722 (22%), Positives = 295/722 (40%), Gaps = 148/722 (20%)
Query: 164 IDYAKLEEDMEYL---SSMPHLAGTKGDYAITNYIRESFKNNGLKLMKEVPFQGYMNFPN 220
+D K E ++L + +PHLAGT+ ++ + I+ +K GL ++ + +++PN
Sbjct: 62 LDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPN 121
Query: 221 EVE---FSVTTSD-NKVHEFALSK------EN-------FNPLSSNGNIQNADIIYANYG 263
+ S+ D N++ +L + EN F+ S G + D++Y NY
Sbjct: 122 KTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQG-MPEGDLVYVNYA 180
Query: 264 TVADIQSLKENGLLS-DNTVLVMKYGNL-PSEQILVAEKHGIKGIIFISKP--------- 312
D L+ + ++ +++ +YG + ++ A+ G KG+I S P
Sbjct: 181 RTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVK 240
Query: 313 -----FGNDGDVIQKLSVAIPQYGTGDALSPGWSTLS-PKKIGLEKSQLVPHIPTIPISY 366
+ G +Q+ ++ + G GD L+PG+ + G+ ++ +P IP PI Y
Sbjct: 241 SYPDGWNLPGGGVQRGNI-LNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGY 299
Query: 367 NQGLKLKSILNDGSPSIKFEDSW-------------FSGRKDDVKCNLRLANAEKTLQPS 413
KL + +P + SW F+G K + + + + +
Sbjct: 300 YDAQKLLEKMGGSAPP---DSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTR-I 355
Query: 414 WNVLGKIEGKEQKDKAIIIAASHDSTCKGTLYPNFGTSSLMALLQLFQQTKYKYDWRPLR 473
+NV+G + G + D+ +I+ DS G + P G + + +++ F K K WRP R
Sbjct: 356 YNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLK-KEGWRPRR 414
Query: 474 NIYFISYDGAQYNHVGATELMETEMNQLKSEVYAFIDISQLSVDPKARRALDVQATPLLQ 533
I F S+D ++ +G+TE E L+ A+I+ + L V TPL+
Sbjct: 415 TILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADS---SIEGNYTLRVDCTPLMY 471
Query: 534 SLFKN-TKQF---DVTVRNIAQYGDWTAYLANGIPTAVLSSPFVLNQTPPIST--CSDDF 587
SL N TK+ D + Y WT P+ S P IS +DF
Sbjct: 472 SLVHNLTKELKSPDEGFEGKSLYESWT----KKSPSPEFSG------MPRISKLGSGNDF 521
Query: 588 QHWSEEIKGTEGA------WE-------QVADTLIYTYE--------------------- 613
+ + + + G WE + ++ TYE
Sbjct: 522 EVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRG 581
Query: 614 -MLLRLIDEPLLPFNVRDYVSNL--------DILFQDLQKQGGNNFDYASIQQGLKAWKK 664
M+ L + +LPF+ RDY L I + Q+ + + S+ +K + +
Sbjct: 582 GMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTE 641
Query: 665 ISDEWNAWVHTW---NNIVMMEDEGVEPSLVSVHRWTWNKKIMNIMKRQSLSSGIPDREF 721
I+ +++ + + N IV+ N ++M + + G+PDR F
Sbjct: 642 IASKFSERLQDFDKSNPIVLR---------------MMNDQLMFLERAFIDPLGLPDRPF 686
Query: 722 YKNVLFGPTLWTQTNGYDSWSFPGVRDALTSGNLK--------EAQKQINIAGNLLISSA 773
Y++V++ P + N Y SFPG+ DAL K E ++QI +A + ++A
Sbjct: 687 YRHVIYAP---SSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAA 743
Query: 774 QS 775
++
Sbjct: 744 ET 745
>At3g54720 [OPR] KOG2195 Transferrin receptor and related proteins containing
the protease-associated (PA) domain
Length = 703
Score = 124 bits (311), Expect = 6e-28
Identities = 153/635 (24%), Positives = 272/635 (42%), Gaps = 81/635 (12%)
Query: 163 SIDYAKLEEDMEYLSSMPHLAGTKGDYAITNYIRESFKNNGLKLMKEVPFQGYMNFPNEV 222
S A + + L+ PHLAGTK +Y+ F++ GL+ ++ +++P +
Sbjct: 71 SASNATISSYLRELTRHPHLAGTKPSLDTLHYVFNHFQSLGLET-HVAEYEALLSYPTHI 129
Query: 223 EFSVTTSDNKVHEFALSK--------ENFNPLSSNGNIQNADIIYANYGTVADIQSLKEN 274
+ + S+ EF L+ ++ S +G+ Q ++++ N+G D +L+
Sbjct: 130 SVTASFSNTTTLEFDLNDVPGDSPVVRPYHAYSPSGSAQG-NVVFVNHGEERDYHALESI 188
Query: 275 GLLSDNTVLVMKYG-NLPSEQIL-VAEKHGIKGIIFISKPFGNDGDVIQKLSVAIPQYGT 332
G+ V++ + G NL I+ +AE G G++ ++ NDG + G
Sbjct: 189 GVSVKGCVVLARKGENLGRGAIVKIAEAKGALGVLIYAE---NDGGGFGGIERGTVMRGI 245
Query: 333 GDALSPGWSTLSPKKIGLEKSQL--------VPHIPTIPISYNQGLKLKSILNDGSPSIK 384
GD +SPGW P +G EK L P IP++P+S + + L ++
Sbjct: 246 GDPVSPGW----PGVVGGEKLSLDDELVTRRFPKIPSLPLSLRNAEIILASLGGARAPLE 301
Query: 385 FEDSWFSGRKDDVKCNLRLAN----AEKTLQPSWNVLGKIEGKEQKDKAIIIAASHDSTC 440
+ +S G V + N E ++ NV+ I G E+ D+ +I+ D+
Sbjct: 302 WRNSGRVGPGQRVGPGRMVINMTFQGEMKMKKINNVVVTIRGSEEADRYVILGNHRDAWT 361
Query: 441 KGTLYPNFGTSSLMALLQLFQQTKYKYDWRPLRNIYFISYDGAQYNHVGATELMETEMNQ 500
G + PN GTS+L+ + + F K WRP R I S+D ++ +G+TE +E +
Sbjct: 362 YGAVDPNSGTSALLDISRRFALL-LKSGWRPRRTILLCSWDAEEFGMIGSTEWIEENVLN 420
Query: 501 LKSEVYAFIDISQLSVDPKAR-RALDVQATPLLQSLFKNTKQFD-----VTV-------R 547
L + A+ L+VD + ATP L L + + D +TV
Sbjct: 421 LGASAVAY-----LNVDCAVQGSGFFAGATPQLDGLLVDVLKLDPDAVGLTVEETFKSQN 475
Query: 548 NIAQY-----GDWTAYLAN-GIPTAVLSSPFVLNQTPPISTCSDDFQHWSEEIKGTEGAW 601
NI Q D++ +L + GIP S P+ + D W I + +
Sbjct: 476 NIIQRLSRVDSDFSGFLHHAGIP----SIDMYYGADYPVYHTAFDSYDWM--IHNADPLF 529
Query: 602 EQ-VADTLIYTYEMLLRLIDEPLLPFNVRDYVSNL----DILFQDLQKQGGNNFDYASIQ 656
+ VA I+ +L L DEPL+PF+ Y L D L + L+ + N +IQ
Sbjct: 530 HRHVAMAGIWGLLGIL-LADEPLIPFDYISYADQLQAHRDKLSKLLEGKVSVNPLSMAIQ 588
Query: 657 QGLKAWKKISDEWNAWVHTWNNIVMMEDEGVEPSLVSVHRWTWNKKIMNIMKRQSLSSGI 716
+ K+ +DE + + + R N ++M + + + GI
Sbjct: 589 EFSLVAKEAADEAKK--------LKGKSYSKNDVAAAAKRRELNDRLMLVERGFLDAEGI 640
Query: 717 PDREFYKNVLFGPTLWTQTN-GYDSWSFPGVRDAL 750
+E++K++++GP ++ G+ FPG+ DA+
Sbjct: 641 KGKEWFKHLVYGPAAEPESKLGF----FPGIADAI 671
>Hs4885507 [OPR] KOG2195 Transferrin receptor and related proteins containing
the protease-associated (PA) domain
Length = 740
Score = 123 bits (308), Expect = 1e-27
Identities = 164/701 (23%), Positives = 283/701 (39%), Gaps = 112/701 (15%)
Query: 164 IDYAKLEEDMEYLSSMPHLAGTKGDYAITNYIRESFKN--NGLKLMKEVPFQGYMNFPNE 221
+D ++ E++ LS PHLA + D + + + +K+ +GL + ++ ++FP++
Sbjct: 52 LDAHRIRENLRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEAXTYEVLLSFPSQ 111
Query: 222 VEFSVTT----SDNKVHEFALSKEN-------------FNPLSSNGNIQNADIIYANYGT 264
+ +V + +H ++EN + + +G Q ++YAN G
Sbjct: 112 EQPNVVDIVGPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGL-LVYANRGA 170
Query: 265 VADIQSLKENGLLSDNTVLVMKYGNLP-SEQILVAEKHGIKGIIFISKPFG-NDG----D 318
D + L+ G+ + T+ + +YG + + + A KHG+ G++ + P NDG D
Sbjct: 171 EEDFKELQTQGIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPD 230
Query: 319 VIQKLSVAIPQYGT---------GDALSPGWSTL-SPKKIGLEKSQLVPHIPTIPISYNQ 368
S +P G GD L+P + S ++ L P IPT PI +
Sbjct: 231 ETFPNSWYLPPSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQD 290
Query: 369 GLKLKSILNDGSPSIKFEDSW---------FSGRKD---DVKCNLRLANAEKTLQPSWNV 416
L LN ++ + F D D + N+ + N + L+ S NV
Sbjct: 291 ARDLLCNLNGTLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLE-LRNSSNV 349
Query: 417 LGKIEGKEQKDKAIIIAASHDSTCKGTLYPNFGTSSLMALLQLFQQTKYKYDWRPLRNIY 476
LG I G + D+ ++ DS G + P+ GT+ L+ L ++ K WRP R+I
Sbjct: 350 LGIIRGAVEPDRYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIV 409
Query: 477 FISYDGAQYNHVGATELMETEMNQLKSEVYAFIDISQLSVDPKARRALDVQATPLLQS-L 535
F S+ ++ +G+TE E N+L+ A+I++ + A L VQ TP +QS +
Sbjct: 410 FASWGAEEFGLIGSTEFTEEFFNKLQERTVAYINV---DISVFANATLRVQGTPPVQSVV 466
Query: 536 FKNTKQF-DVTVRNIAQYGDWTAYLANGIPTAVL------------SSPFV--------- 573
F TK+ +++ Y +W Y P L +PFV
Sbjct: 467 FSATKEIRSPGPGDLSIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMD 526
Query: 574 -----------LNQTPPISTCSDDFQHWSEEIKGTEGAWEQVADTLIYTYEMLLRLIDEP 622
P T D F + + + + + VA T ++LRL D
Sbjct: 527 IAYTYDRSKTSARIYPTYHTAFDTFDYVDKFLDPGFSSHQAVART---AGSVILRLSDSF 583
Query: 623 LLPFNVRDYVSNLDILFQDLQKQGGNNFDYASIQQG--LKAWKKISDEWNAWVHTWNNIV 680
LP V DY L Q Q+ G + SI G + A +K E A I
Sbjct: 584 FLPLKVSDYSETLRSFLQAAQQDLGALLEQHSISLGPLVTAVEKFEAEAAA---LGQRIS 640
Query: 681 MMEDEGVEPSLVSVHRWTWNKKIMNIMKRQSLSSGIPDREFYKNVLFGPTLWTQTNGYDS 740
++ +P V + N ++M + + P+ +Y +V LW ++G S
Sbjct: 641 TLQKGSPDPLQVRM----LNDQLMLLERTFLNPRAFPEERYYSHV-----LWAPSHGLRS 691
Query: 741 WSFPGVRDALT--------SGNLKEAQKQINIAGNLLISSA 773
PG+ +A + S E Q+Q++I L +A
Sbjct: 692 -HIPGLSNACSRARDTASGSEAWAEVQRQLSIVVTALEGAA 731
>Hs20480969 [OPR] KOG2195 Transferrin receptor and related proteins containing
the protease-associated (PA) domain
Length = 693
Score = 119 bits (297), Expect = 2e-26
Identities = 153/719 (21%), Positives = 292/719 (40%), Gaps = 142/719 (19%)
Query: 164 IDYAKLEEDMEYL---SSMPHLAGTKGDYAITNYIRESFKNNGLKLMKEVPFQGYMNFPN 220
+D K E ++L + +PHLAGT+ ++ + I+ +K GL + + +++PN
Sbjct: 5 LDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSAELAHYDVLLSYPN 64
Query: 221 EVE---FSVTTSD-NKVHEFALSKE-------------NFNPLSSNGNIQNADIIYANYG 263
+ S+ D N++ +L + +F+ S G + D+++ NY
Sbjct: 65 KTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPSFSAFSPQG-MPEGDLVHVNYA 123
Query: 264 TVADIQSLKENGLLS-DNTVLVMKYGNL-PSEQILVAEKHGIKGIIFISKP--------- 312
D L+ + ++ +++ +Y + ++ A+ G KG+I S P
Sbjct: 124 RTEDFFKLERDMKINCSGKIVIARYRKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVK 183
Query: 313 -----FGNDGDVIQKLSVAIPQYGTGDALSPGWSTLS-PKKIGLEKSQLVPHIPTIPISY 366
+ G +Q+ ++ + G GD L+PG+ + G+ ++ +P IP P+ Y
Sbjct: 184 SYPDGWNLPGGGVQRGNI-LNLNGAGDPLTPGYPANEYAYRHGIAEAVGLPSIPVHPVGY 242
Query: 367 NQGLKLKSILNDGSPSIKFEDSW-------------FSGRKDDVKCNLRLANAEKTLQPS 413
KL + +P + SW F+G K + + + + +
Sbjct: 243 YDAQKLLEKMGGSAPP---DSSWRGSLKVSYNVGPGFTGNFSTQKVKMHIHSTNEVTR-I 298
Query: 414 WNVLGKIEGKEQKDKAIIIAASHDSTCKGTLYPNFGTSSLMALLQLFQQTKYKYDWRPLR 473
+NV+G + G + D+ +I+ DS G + P G + + ++ F K K WRP R
Sbjct: 299 YNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHETVRSFGTLK-KEGWRPRR 357
Query: 474 NIYFISYDGAQYNHVGATELMETEMNQLKSEVYAFIDISQLSVDPKARRALDVQATPLLQ 533
I F S+D ++ +G+TE E L+ A+I+ + L V TPL+
Sbjct: 358 TILFASWDAEEFGLLGSTEWAEDNSRLLQERGVAYINADS---SIEGNYTLRVDCTPLMY 414
Query: 534 SLF----KNTKQFDVTVRNIAQYGDWTAYLANGIPTAVLSSPFVLNQTPPIST--CSDDF 587
SL K K D + Y WT P+ S P IS +DF
Sbjct: 415 SLVYNLTKELKSPDEGFEGKSLYESWT----KKSPSPEFSG------MPRISKLGSGNDF 464
Query: 588 QHWSEEIKGTEGA------WE-------QVADTLIYTYE--------------------- 613
+ + + + G WE + ++ TYE
Sbjct: 465 EVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRG 524
Query: 614 -MLLRLIDEPLLPFNVRDYVSNL--------DILFQDLQKQGGNNFDYASIQQGLKAWKK 664
M+ L + +LPF+ RDY L +I + Q+ + + S+ +K + +
Sbjct: 525 GMVFELANSIVLPFDCRDYAVVLRKYADKIYNISMKHPQEMKTYSLSFDSLFSAVKNFTE 584
Query: 665 ISDEWNAWVHTWNNIVMMEDEGVEPSLVSVHRWTWNKKIMNIMKRQSLSSGIPDREFYKN 724
I+ +++ + ++ P L+ + N ++M + + G+PDR FY++
Sbjct: 585 IASKFSERLQDFDK--------SNPILLRM----MNDQLMFLERAFIDPLGLPDRPFYRH 632
Query: 725 VLFGPTLWTQTNGYDSWSFPGVRDALTSGNLK--------EAQKQINIAGNLLISSAQS 775
V++ P + N Y SFPG+ DAL K + ++QI++A + ++A++
Sbjct: 633 VIYAP---SSHNKYAGESFPGIYDALFDIESKVDPSKAWGDVKRQISVAAFTVQAAAET 688
>CE12844 [OPR] KOG2195 Transferrin receptor and related proteins containing
the protease-associated (PA) domain
Length = 751
Score = 114 bits (284), Expect = 8e-25
Identities = 108/452 (23%), Positives = 201/452 (43%), Gaps = 72/452 (15%)
Query: 165 DYAKLEEDMEYL---SSMPHLAGTKGDYAITNYIRESFKNNGLKLMKEVPFQGYMNFPN- 220
D K E +YL + PH+AGT+ + + I ++ GL+ + +P++ +++P+
Sbjct: 51 DNIKTENIKKYLRIFTKDPHVAGTEANKKVAYEIANAWSEAGLEDVHTLPYEVLLSYPDF 110
Query: 221 EVEFSVTTSDNKVHEFALSK-----------------ENFNPLSSNGNIQNADIIYANYG 263
E SV + E SK + + NG+ +AD++Y N+G
Sbjct: 111 ENPNSVIIKSSAGKEVFKSKGVSPVIIPDEQSGKYAGHQWLAYAGNGSA-SADVVYINHG 169
Query: 264 TVADIQSLKENGLLSDNTVLVMKYGN-LPSEQILVAEKHGIKGIIFISKPF-----GNDG 317
T D ++LK G+ + +M+YG+ ++I A++ G G I S G +
Sbjct: 170 TANDFKNLKLMGVDIKGKIALMRYGHGFRGDKIHKAQQAGAIGAILFSDTQDVAQDGVES 229
Query: 318 DVIQKLSVAIPQ---------YGTGDALSPGWSTLSPKKIGLEKSQLV---------PHI 359
+ + + +P +G GDALSP + P K L K + + P I
Sbjct: 230 ENVYPKKIWMPNEGVQRGSLMHGDGDALSPYY----PSKKELFKGRTIEEAKEDGVLPSI 285
Query: 360 PTIPISYNQGLKLKSILND------------GSPSIKFEDSWFSGRKDDVKCNLRLANAE 407
P +P+SY G ++ L+ G+ + K + +G K + + L
Sbjct: 286 PVLPVSYTTGYEILKRLSGRPAPSDWQGFVGGNLTYKLGPGFVNGEKLSINVHSELRT-- 343
Query: 408 KTLQPSWNVLGKIEGKEQKDKAIIIAASHDSTCKGTLYPNFGTSSLMALLQLFQQTKYKY 467
K ++ NV+G I G E+ D I++ D+ G++ PN GT+ L + + QT +
Sbjct: 344 KRIR---NVIGYIRGSEEPDSYIMLGNHFDAWVYGSIDPNSGTAVLAEVARAMMQTINET 400
Query: 468 DWRPLRNIYFISYDGAQYNHVGATELMETEMNQLKSEVYAFIDISQLSVDPKARRALDVQ 527
W+P R I F ++D ++ +G+TE +E +N L+ +I++ + + +L V
Sbjct: 401 SWKPARTIVFNAWDAEEFGLIGSTEFVEEFVNILQKRAVVYINMDCI----QGNISLHVD 456
Query: 528 ATPLLQ-SLFKNTKQFDVTVRNIAQYGDWTAY 558
P+L+ ++ + +KQ + + G T Y
Sbjct: 457 TVPILEHAVIEASKQVENPSKRERSRGRKTLY 488
>CE08584 [OPR] KOG2195 Transferrin receptor and related proteins containing
the protease-associated (PA) domain
Length = 1483
Score = 102 bits (253), Expect = 3e-21
Identities = 110/513 (21%), Positives = 213/513 (41%), Gaps = 89/513 (17%)
Query: 120 VYILFMSVIVYTVVMSGLM-----PNSKSTATIGMFSDKNQLIYYARRSIDYAKLEEDME 174
V ++ +S + T+++S + NSK + + ++ QLI ++D + ++
Sbjct: 29 VVLVAVSTVALTIILSNAIHQSYKSNSKPLPKLSIATNIKQLI-----NVD--NIRSNLH 81
Query: 175 YLSSMPHLAGTKGDYAITNYIRESFKNNGLKLMKEVPFQGYMNFPN-------------- 220
L+ PH+AGT+ + + IR+ GL+ + + +++PN
Sbjct: 82 SLTKKPHVAGTENNLRVAEMIRDQMITQGLENVHFNEYNVMLSYPNWTTPNIIEILKENR 141
Query: 221 EVEFSVTTSDNKVHEFALSKENFNPL--------SSNGNIQNADIIYANYGTVADIQSLK 272
++ FS T V + +E +PL S+ G ++ DI+Y N +DI+ L+
Sbjct: 142 DLVFSTTGRSVSV----IKEEQNDPLAEIQWLAYSAAGTVEG-DIVYVNNANPSDIEYLE 196
Query: 273 ENGL-LSDNTVLVMKYGNLPSEQILVAEKHGIKGIIFISKP-------------FGND-- 316
G+ L D L N +A K G K + S P +GN
Sbjct: 197 SLGIDLKDKIFLARYSSNYRGNIAQMAVKKGAKACLVYSDPKQVASLGTGPNETYGNTDK 256
Query: 317 --GDVIQKLSVAIPQYGTGDALSPGWSTLSP-----KKIGLEKSQLVPHIPTIPISYN-- 367
+ +Q SV I G GD +P + ++ + L + +P IP +PI+Y
Sbjct: 257 MPSNTVQMGSVYI---GLGDPRTPAFPSIGDLFKEKTEQDLLDEKKIPTIPMLPITYATA 313
Query: 368 ----QGLKLKSILNDGSPSIKFEDSWFSG--RKDDVKCNLRLANAEKTL----------- 410
+ +K ++ D + + G ++ + N E+++
Sbjct: 314 QILFENMKGDAVNADFQGKLNVTYRYGPGLINNQKLRVTVHAENEERSVIVVELISRLRL 373
Query: 411 --QPSWNVLGKIEGKEQKDKAIIIAASHDSTCKGTLYPNFGTSSLMALLQLFQQTKYKYD 468
+ N++G I+G ++ DK ++++ +D+ G + PN GTS+L+ + + +Q + +
Sbjct: 374 NFRKIQNIMGYIKGSQEPDKFVLVSNHYDAWTYGAVDPNSGTSTLLEVSRALKQYQNQTG 433
Query: 469 WRPLRNIYFISYDGAQYNHVGATELMETEMNQLKSEVYAFIDISQLSVDPKARRALDVQA 528
W P R+I F +D +Y +G+TE E QL A I++ + + +
Sbjct: 434 WIPARSILFAHWDAEEYGLIGSTEFAEEYRLQLMRRAVAVINMDLIGGNQTLLGLSNPTV 493
Query: 529 TPLLQSLFKNTKQFDVTVRNIAQ---YGDWTAY 558
+L+S N +Q + T + Y W Y
Sbjct: 494 ANVLRSAAANVEQPNPTEMEQGRKTLYDSWKYY 526
>Hs4507455 [OPR] KOG2195 Transferrin receptor and related proteins containing
the protease-associated (PA) domain
Length = 780
Score = 95.9 bits (237), Expect = 2e-19
Identities = 129/525 (24%), Positives = 227/525 (42%), Gaps = 81/525 (15%)
Query: 168 KLEEDMEYLSSMPHLAGTKGDYAITNYIRESFKNNGLKLMKEVPFQGYMNFPNEVEFSV- 226
+LE+ + S +AG+ G A+T IR + L + + FP+ +
Sbjct: 152 RLEDTIRQTSLRERVAGSAGMAALTQDIRAALSRQKLDHVWTDTHYVGLQFPDPAHPNTL 211
Query: 227 --TTSDNKVHEFALSKEN---FNPLSSNGNIQNADIIYANYGTVADIQSLKENGLLSDNT 281
KV E L E+ + P S+ GN+ +++YA+YG D+Q L+ G+
Sbjct: 212 HWVDEAGKVGE-QLPLEDPDVYCPYSAIGNV-TGELVYAHYGRPEDLQDLRARGVDPVGR 269
Query: 282 VLVMKYGNLP-SEQILVAEKHGIKGIIFISKPFGNDGDVIQKLSVAIPQ-------YGTG 333
+L+++ G + ++++ A+ G +G++ +P D K S++ Q GTG
Sbjct: 270 LLLVRVGVISFAQKVTNAQDFGAQGVLIYPEPADFSQDP-PKPSLSSQQAVYGHVHLGTG 328
Query: 334 DALSPGWSTLSPKKIGLEKSQLVPHIPTIPISYNQGLKLKSILNDG-SPSIKFEDSWFSG 392
D +PG+ + + ++Q + P P + QG L S + G P ++
Sbjct: 329 DPYTPGFPSFN-------QTQKLKG-PVAPQEW-QGSLLGSPYHLGPGPRLRL------- 372
Query: 393 RKDDVKCNLRLANAEKTLQPSWNVLGKIEGKEQKDKAIIIAASHDSTCKGTLYPNFGTSS 452
+ N +T P N+ G IEG+ + D ++I A D+ G GT+
Sbjct: 373 ----------VVNNHRTSTPINNIFGCIEGRSEPDHYVVIGAQRDAWGPGAAKSAVGTAI 422
Query: 453 LMALLQLFQQTKYKYDWRPLRNIYFISYDGAQYNHVGATELMETEMN--QLKSEVYAFID 510
L+ L++ F + +RP R++ FIS+DG + VG+TE +E ++ LK+ VY +D
Sbjct: 423 LLELVRTF-SSMVSNGFRPRRSLLFISWDGGDFGSVGSTEWLEGYLSVLHLKAVVYVSLD 481
Query: 511 ISQLSVDPKARRALDVQATPLLQSLFKNT-KQFD--------VTVRNIAQYGDWTAYLAN 561
+ L D + +PLL SL ++ KQ D + + + W A +
Sbjct: 482 NAVLGDD-----KFHAKTSPLLTSLIESVLKQVDSPNHSGQTLYEQVVFTNPSWDAEVIR 536
Query: 562 GIP---TAVLSSPFVLNQTPPISTCSDD----FQHWSEEI-----KGTEGAWEQVADTLI 609
+P +A + FV S DD F H E+ K +G VA +
Sbjct: 537 PLPMDSSAYSFTAFVGVPAVEFSFMEDDQAYPFLHTKEDTYENLHKVLQGRLPAVAQAVA 596
Query: 610 -YTYEMLLRLIDEPLLPFN-------VRDYVSNLDILFQDLQKQG 646
++L+RL + LLP + V ++ NL+ DL+ +G
Sbjct: 597 QLAGQLLIRLSHDRLLPLDFGRYGDVVLRHIGNLNEFSGDLKARG 641
>Hs4507457 [OPR] KOG2195 Transferrin receptor and related proteins containing
the protease-associated (PA) domain
Length = 760
Score = 87.4 bits (215), Expect = 8e-17
Identities = 88/403 (21%), Positives = 170/403 (41%), Gaps = 17/403 (4%)
Query: 163 SIDYAKLEEDMEYLSSMPHLAGTKGDYAITNYIRESFKNNGL-KLMKEVPFQGYMNFPNE 221
S D+ + + S +P AG++ D + Y+ F+ L K+ ++ F +
Sbjct: 137 STDFTSTIKLLNENSYVPREAGSQKDENLALYVENQFREFKLSKVWRDQHFVKIQVKDSA 196
Query: 222 VEFSVTTSDNKVHEFALSKENFNPLSSNGNIQNADIIYANYGTVADIQSLKENGLLSDNT 281
+ N + + S +++AN+GT D + L + +
Sbjct: 197 QNSVIIVDKNGRLVYLVENPGGYVAYSKAATVTGKLVHANFGTKKDFEDLYTP---VNGS 253
Query: 282 VLVMKYGNLP-SEQILVAEKHGIKGIIFISKPFGNDGDVIQKLSVAIPQYGTGDALSPGW 340
+++++ G + +E++ AE G++ + GTGD +PG+
Sbjct: 254 IVIVRAGKITFAEKVANAESLNAIGVLIYMDQTKFPIVNAELSFFGHAHLGTGDPYTPGF 313
Query: 341 STLSPKKIGLEKSQLVPHIPTIPISYNQGLKLKSILNDGSPSIKFEDS---WFSGRKDDV 397
+ + + +S +P+IP IS KL + PS DS + +V
Sbjct: 314 PSFNHTQFPPSRSSGLPNIPVQTISRAAAEKLFGNMEGDCPSDWKTDSTCRMVTSESKNV 373
Query: 398 KCNLRLANAEKTLQPSWNVLGKIEGKEQKDKAIIIAASHDSTCKGTLYPNFGTSSLMALL 457
K L ++N K ++ N+ G I+G + D +++ A D+ G GT+ L+ L
Sbjct: 374 K--LTVSNVLKEIK-ILNIFGVIKGFVEPDHYVVVGAQRDAWGPGAAKSGVGTALLLKLA 430
Query: 458 QLFQQTKYKYDWRPLRNIYFISYDGAQYNHVGATELMETEMNQLKSEVYAFIDISQLSVD 517
Q+F K ++P R+I F S+ + VGATE +E ++ L + + +I++ + +
Sbjct: 431 QMFSDMVLKDGFQPSRSIIFASWSAGDFGSVGATEWLEGYLSSLHLKAFTYINLDKAVL- 489
Query: 518 PKARRALDVQATPLLQSLFKNTKQ---FDVTVRNIAQYGDWTA 557
V A+PLL +L + T Q VT + + Q +W +
Sbjct: 490 --GTSNFKVSASPLLYTLIEKTMQNVKHPVTGQFLYQDSNWAS 530
>At4g07670 [OPR] KOG2195 Transferrin receptor and related proteins containing
the protease-associated (PA) domain
Length = 280
Score = 73.6 bits (179), Expect = 1e-12
Identities = 70/257 (27%), Positives = 114/257 (44%), Gaps = 41/257 (15%)
Query: 257 IIYANYGTVADIQSLKEN-GLLSDNTVLVMKYGNLPSEQILV-AEKHGIKGIIFISKPFG 314
++YANYG V D LK++ G+ V++ +YG + I+ A + G G++ +
Sbjct: 10 VVYANYGRVEDFVRLKKDMGVNVSGAVVIARYGQIYKVDIVNNAYEAGAVGVVIYTNKRD 69
Query: 315 NDGDVIQKLSVAIP----QYGT-----GDALSPGWSTLSP----KKIGLEKSQLVPHIPT 361
GD S +P Q GT GD +PGW+++ +E S VP IP+
Sbjct: 70 YGGDEWFPASKWMPPSGFQVGTVYNGLGDPTTPGWASVDGCERLSDEAVELSGDVPLIPS 129
Query: 362 IPISYNQG-LKLKSILNDGSPSIKFEDSWFSGRKDDVKCNLRLANAEKTLQPSWNVLGKI 420
+P+S + LK+I+ D P L L+ +Q NV+G I
Sbjct: 130 LPVSAADAEVILKTIVGDVGPGPGI---------------LNLSYIVTKIQ---NVIGVI 171
Query: 421 EGKEQKDKAIIIAASHDSTCKGTLYPNFGTSSLMALLQLFQQ-------TKYKYDWRPLR 473
EG+E+ D+ +I+ D+ + PN GT+ LM + + Q K W+P R
Sbjct: 172 EGEEEPDRYVILRNHRDTWTFRAVDPNSGTAVLMEASKSYLQHIAQRLDKLQKRGWKPRR 231
Query: 474 NIYFISYDGAQYNHVGA 490
I ++D +Y V +
Sbjct: 232 TIILCNWDAEEYGLVSS 248
>YJR126c [OPR] KOG2195 Transferrin receptor and related proteins containing
the protease-associated (PA) domain
Length = 811
Score = 70.1 bits (170), Expect = 1e-11
Identities = 96/498 (19%), Positives = 194/498 (38%), Gaps = 70/498 (14%)
Query: 85 KNNVVDPLVQVYQMASAKVDLYLSKLGNPLILRRFVYILFMSVIVYTVVMSGLMPNSKST 144
++N + +V Y++ +D +F+Y++ S+++Y ++ P + +
Sbjct: 67 RSNTISSIVSGYEIMKEHMDK-----------EKFMYLILASLLLYMGFVAAFAPRTSLS 115
Query: 145 ATIGMFSDKNQL------IYYARRSIDYAKLEEDMEYLSSMPHLAGTKGDYAITNYIRES 198
F IY + E +Y M + A D + Y +
Sbjct: 116 RDFRRFHSSRLTNAEVYRIYLNSLQQENRAKEHVYKYAGYMSNGAS---DSSTFKYTLDE 172
Query: 199 FKNNGLKLMKEVPFQGYMNFPNEVEFSVTTSDNKVHEFALSKEN---------------F 243
F + G K E + ++ P + + + V+E ++ ++ F
Sbjct: 173 FLDMGYKPKVE-KYYPWIGEPVDTNVAPLENGKVVYEASMIEDRVKGDPASHARKRQKGF 231
Query: 244 NPLSSNGNIQNADIIYANYGTVADIQSLKENGLLSDNTVLVMKYGN-LPSEQILVAEKHG 302
+ S NG++ A ++ NYG+++D + L + + ++ + +++ G LP ++ AE +G
Sbjct: 232 HQYSKNGSV-TARYVFCNYGSISDYKLLLKKNIDIEDKIHIVRSGKILPGLKVKNAELYG 290
Query: 303 IKGIIFISKPFGNDGDVIQKLSVAIPQYG-------------------TGDALSPGWSTL 343
+I + PF +DG V ++ YG GD +PG+ +
Sbjct: 291 ASSVIIYTDPF-DDGKVTEENGFLHYPYGPARNPSYIRRDSVNYFSDTPGDPTTPGYPSK 349
Query: 344 SPKKIGLEKSQLVPHIPTIPISYNQGLKLKSILNDG----SPSIKFED-SWFSGRKDDVK 398
+ VP IP++P+S + LN P +D F+G +
Sbjct: 350 DSDTEHMSPVGRVPRIPSVPMSARDVQPILERLNGRGFQIGPGSNIKDFGSFTGPSSSID 409
Query: 399 CNLRLAN-AEKTLQPSWNVLGKIEGKEQKDKAIIIAASHDSTCKGTLYPNFGTSSLMALL 457
+ L N ++ +V I G + + III A DS + S+++ +
Sbjct: 410 -KVHLHNELTYNIKEMSSVEVSIPGIFTEGE-IIIGAHRDSLASSSAGDANSGSAILLEI 467
Query: 458 QLFQQTKYKYDWRPLRNIYFISYDGAQYNHVGATELMETEMNQLKSEVYAFIDISQLSVD 517
K+ W+PLR I IS+DG + +G+T+ E L+ ++++ +
Sbjct: 468 ARGMSKLLKHGWKPLRPIKLISWDGERSGLLGSTDYAEAHAAILRRRALVYLNLD----N 523
Query: 518 PKARRALDVQATPLLQSL 535
+ +A PLLQ +
Sbjct: 524 AISGTNFHCKANPLLQDV 541
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.134 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,436,430
Number of Sequences: 60738
Number of extensions: 2180145
Number of successful extensions: 5570
Number of sequences better than 1.0e-05: 15
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 5500
Number of HSP's gapped (non-prelim): 29
length of query: 784
length of database: 30,389,216
effective HSP length: 114
effective length of query: 670
effective length of database: 23,465,084
effective search space: 15721606280
effective search space used: 15721606280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)