ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2450 good L KOG0968 Replication, recombination and repair DNA polymerase zeta, catalytic subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII2450 857963 853611 -1451
(1451 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL167c [L] KOG0968 DNA polymerase zeta catalytic subunit 1245 0.0
SPAC688.10 [L] KOG0968 DNA polymerase zeta catalytic subunit 667 0.0
Hs4506483 [L] KOG0968 DNA polymerase zeta catalytic subunit 649 0.0
At1g67500 [L] KOG0968 DNA polymerase zeta catalytic subunit 601 e-171
7304154 [L] KOG0968 DNA polymerase zeta catalytic subunit 550 e-156
CE27403 [L] KOG0968 DNA polymerase zeta catalytic subunit 365 e-100
7294203 [L] KOG0969 DNA polymerase delta catalytic subunit 290 9e-78
SPBC336.04 [L] KOG0969 DNA polymerase delta catalytic subunit 278 5e-74
At5g63960 [L] KOG0969 DNA polymerase delta catalytic subunit 277 8e-74
Hs4505933 [L] KOG0969 DNA polymerase delta catalytic subunit 276 2e-73
ECU09g0430 [L] KOG0969 DNA polymerase delta catalytic subunit 261 6e-69
CE09308 [L] KOG0969 DNA polymerase delta catalytic subunit 258 5e-68
YDL102w [L] KOG0969 DNA polymerase delta catalytic subunit 255 3e-67
Hs8393995 [L] KOG0970 DNA polymerase alpha catalytic subunit 137 2e-31
SPAC3H5.06c [L] KOG0970 DNA polymerase alpha catalytic subunit 129 3e-29
ECU05g0990 [L] KOG0970 DNA polymerase alpha catalytic subunit 127 1e-28
CE26106 [L] KOG0970 DNA polymerase alpha catalytic subunit 121 7e-27
At5g67100 [L] KOG0970 DNA polymerase alpha catalytic subunit 115 4e-25
YNL102w [L] KOG0970 DNA polymerase alpha catalytic subunit 107 1e-22
7300763 [L] KOG0970 DNA polymerase alpha catalytic subunit 100 3e-20
>YPL167c [L] KOG0968 DNA polymerase zeta catalytic subunit
Length = 1504
Score = 1245 bits (3221), Expect = 0.0
Identities = 672/1504 (44%), Positives = 937/1504 (61%), Gaps = 80/1504 (5%)
Query: 10 SSLDSNEINIQINNSDSYQCFPTLLDCKTSKSLPGLRFVQVPVLRFYGCLSTGHKVLIHC 69
SS S+ IQ+NN D Y PT LD +SLP +F QVP +R +G L TGH+VL H
Sbjct: 16 SSSKSDYFRIQLNNQDYYMSKPTFLDPSHGESLPLNQFSQVPNIRVFGALPTGHQVLCHV 75
Query: 70 HGIFPYIFIKYDGHSNDKASVIRNRCTSLHKILETRMIETFT-KTDFK-----EKLTSLK 123
HGI PY+FIKYDG D +++ RC +HK LE ++ +F K D K +KL +L
Sbjct: 76 HGILPYMFIKYDGQITDTSTLRHQRCAQVHKTLEVKIRASFKRKKDDKHDLAGDKLGNLN 135
Query: 124 YIANVSVVKGVPFYGYHVGYEPYYKITLLNGSYSNKLSELLRDGRIFTSKVDVFEAHIPY 183
++A+VSVVKG+PFYGYHVG+ +YKI+LLN S +++SEL+RDG+IF K +++E+HIPY
Sbjct: 136 FVADVSVVKGIPFYGYHVGWNLFYKISLLNPSCLSRISELIRDGKIFGKKFEIYESHIPY 195
Query: 184 LLQMMADYNLFGCGWLKLSKCYFRQPVLLTDLDMNEILHTDSLERFLKKHLHPNQNVLDI 243
LLQ AD+NLFGC W+ + +CYFR PVL + LD++++ D L+ L + NVL
Sbjct: 196 LLQWTADFNLFGCSWINVDRCYFRSPVLNSILDIDKLTINDDLQLLLDRFCDFKCNVLSR 255
Query: 244 DPFHRIGKTFLEMDIIPQFILNREEIQFRDLHHDFVELKKDLQTSD-QGYVNSTKDIWKE 302
F R+G +E+DI+PQFI NRE++Q RD+HHDF+E D+ + YV+S +D+ E
Sbjct: 256 RDFPRVGNGLIEIDILPQFIKNREKLQHRDIHHDFLEKLGDISDIPVKPYVSSARDMINE 315
Query: 303 IQLLRKRKGLAEYEGLKEIFRESQLQYNWKEDERLVKHFDEAKKRMSSLFNKEKALNFDN 362
+ + R+ L EY+ E R + W+ + +A+ + S+ + NF+N
Sbjct: 316 LTMQREELSLKEYKEPPETKRHVS-GHQWQSSGEFEAFYKKAQHKTSTFDGQIP--NFEN 372
Query: 363 FVDPFINENFFA--STKDALQELWPKIP------------RNASSKVFCWSEVEF-KLNN 407
F+D N+ F A + +AL +LWP++P +N ++E E ++N
Sbjct: 373 FIDK--NQKFSAINTPYEALPQLWPRLPQIEINNNSMQDKKNDDQVNASFTEYEICGVDN 430
Query: 408 QYTSVREQKVASTNTKNIPXXXXXXXXXXXXXXXXXKRAEESSCHDDIA---NEAIARKL 464
+ V+ + S + +P K + D A N A RKL
Sbjct: 431 ENEGVKGSNIKSRSYSWLPESIASPKDSTILLDHQTKYHNTINFSMDCAMTQNMASKRKL 490
Query: 465 ----AKRKTSAIRKSTFRPMI-------------RPSVTHANIKESLSANQIEEVQYNDP 507
+ KTS + + + M P + +I L ++ Y DP
Sbjct: 491 RSSVSANKTSLLSRKRKKVMAAGLRYGKRAFVYGEPPFGYQDILNKLEDEGFPKIDYKDP 550
Query: 508 FFSNPLDCKRLQTEMAGRVFKLSSDHILFKRSIRSNDTTATLTSSGSVYARSRWKYIRPK 567
FFSNP+D + AG+ F++SS H+ + ++ T ++ + + S WKY
Sbjct: 551 FFSNPVDLENKPYAYAGKRFEISSTHVSTRIPVQFGGETVSVYNKPTFDMFSSWKYALKP 610
Query: 568 PSFKRIANAMKPF-----KGKFSMVEGKTPELPFGYKFKSN----KIEKNNNASNRMTHF 618
P++ + K S + TP F YKF S+ + K ++ + +TH
Sbjct: 611 PTYDAVQKWYNKVPSMGNKKTESQISMHTPHSKFLYKFASDVSGKQKRKKSSVHDSLTHL 670
Query: 619 TMEIHVNTREDKFPDPKYDAVRMIFWKVQDGTFPFDLDITQEGVLIFLDDVSTENSWKTA 678
T+EIH NTR DK PDP D V MI W +++ TFP DLDI EG++I + S ++++ T
Sbjct: 671 TLEIHANTRSDKIPDPAIDEVSMIIWCLEEETFPLDLDIAYEGIMI-VHKASEDSTFPTK 729
Query: 679 DP----SVHITAYYDELEMIYALEDLVRFFDPDILSGYEIHSSSWGYLIDRCHKGHDYDV 734
+ + Y E EM AL DLV DPDILSG+EIH+ SWGY+I+RC K H +D+
Sbjct: 730 IQHCINEIPVMFYESEFEMFEALTDLVLLLDPDILSGFEIHNFSWGYIIERCQKIHQFDI 789
Query: 735 EDELSRVDYNQSSKKKDRWGYTHATAFSITGRQMLNIWRPLRSSLNLLDYTLENIAFHVL 794
EL+RV +K D WGY H++ ITGR M+NIWR LRS +NL YT+E+ AF++L
Sbjct: 790 VRELARVKCQIKTKLSDTWGYAHSSGIMITGRHMINIWRALRSDVNLTQYTIESAAFNIL 849
Query: 795 HQRLPFYSYKTRTEFYESMDETSK-RCLLFYWITRLRVNFKLLETQNIIGKTIEQARLIG 853
H+RLP +S+++ T + + T++ + +L YW++R ++N +LL Q+ I + IEQARLIG
Sbjct: 850 HKRLPHFSFESLTNMWNAKKSTTELKTVLNYWLSRAQINIQLLRKQDYIARNIEQARLIG 909
Query: 854 IDFYSVLYRGSQYKVESFLIRLCKSEQFILISPSRMQVRNQKALECIPLVMEPSSAFYKS 913
IDF+SV YRGSQ+KVESFLIR+CKSE FIL+SP + VR QKALEC+PLVMEP SAFYKS
Sbjct: 910 IDFHSVYYRGSQFKVESFLIRICKSESFILLSPGKKDVRKQKALECVPLVMEPESAFYKS 969
Query: 914 PLLVLDFQSLYPSIVMAYNYCYSTIIGRVESLNTKNNEIGITRYDIPEDLLTLISDYITI 973
PL+VLDFQSLYPSI++ YNYCYST+IGRV +N N +G++++ +P ++L L+ + +TI
Sbjct: 970 PLIVLDFQSLYPSIMIGYNYCYSTMIGRVREINLTENNLGVSKFSLPRNILALLKNDVTI 1029
Query: 974 SPNGIVFVKKELRKSVLAKMLKDILDTRFLMKSTMKELNDEHNLIN-MLDNRQEALKLLA 1032
+PNG+V+ K +RKS L+KML DILD R ++K TM E+ D++ + +L+N+Q ALKLLA
Sbjct: 1030 APNGVVYAKTSVRKSTLSKMLTDILDVRVMIKKTMNEIGDDNTTLKRLLNNKQLALKLLA 1089
Query: 1033 NVTYGYTSASFSGRMPCSDIADSIVQTGRETLERAIEVIETTKEWGAKVVYGDTDSLFVY 1092
NVTYGYTSASFSGRMPCSD+ADSIVQTGRETLE+AI++IE + W AKVVYGDTDSLFVY
Sbjct: 1090 NVTYGYTSASFSGRMPCSDLADSIVQTGRETLEKAIDIIEKDETWNAKVVYGDTDSLFVY 1149
Query: 1093 LPGKSKDEAFVIGRQIAEEITRQNPKPIELKFEKVYHPCFLVTKKRYVGFSYESEYQKEP 1152
LPGK+ EAF IG +AE +T+ NPKPI LKFEKVYHP L++KKRYVGFSYES Q P
Sbjct: 1150 LPGKTAIEAFSIGHAMAERVTQNNPKPIFLKFEKVYHPSILISKKRYVGFSYESPSQTLP 1209
Query: 1153 KFDAKGIETVRRDGTPAQQKIVEKALRIMFETTDLSMVKEYLIGEFDKIITGRVNIQDFC 1212
FDAKGIETVRRDG PAQQKI+EK +R++F+T DLS +K+YL EF KI G+V+ QDFC
Sbjct: 1210 IFDAKGIETVRRDGIPAQQKIIEKCIRLLFQTKDLSKIKKYLQNEFFKIQIGKVSAQDFC 1269
Query: 1213 FAREVKLGHYKSEKTAPPGAQIAMQMMEEDARTEPQYKQRVPYVVKMGKIGETLSSRCLS 1272
FA+EVKLG YKSEKTAP GA + + + ED R EPQYK+R+PY+V GK G+ L RC+S
Sbjct: 1270 FAKEVKLGAYKSEKTAPAGAVVVKRRINEDHRAEPQYKERIPYLVVKGKQGQLLRERCVS 1329
Query: 1273 PEAFLRSKTSRLDYTYYIVKNIIPPLQRFFQLVGVDIMDW----YISMKHTLNPLKVDSD 1328
PE FL + LD YYI K +IPPL R F L+G+++ +W S + + KV+
Sbjct: 1330 PEEFLEGENLELDSEYYINKILIPPLDRLFNLIGINVGNWAQEIVKSKRASTTTTKVE-- 1387
Query: 1329 DGSHEGRSLTSIVKGKSCLRCRKKVHPKFISPICGECRIDKSNTTL-FLEESVRLKQSKM 1387
++T + +C C +++ +C +C +S TTL FL + +LK+ K
Sbjct: 1388 -------NITRVGTSATCCNCGEELTKICSLQLCDDCLEKRSTTTLSFLIK--KLKRQKE 1438
Query: 1388 HSVMRT-CQTCSYKFHKDAMAPLDQIALKCQSKDCPVYFSKFKYMNGLKDNDMRDLLMGL 1446
+ ++T C+TCSY++ DA D IA KC S DCPV++S+ K L+DN L
Sbjct: 1439 YQTLKTVCRTCSYRYTSDAGIENDHIASKCNSYDCPVFYSRVKAERYLRDNQSVQREEAL 1498
Query: 1447 IDLD 1450
I L+
Sbjct: 1499 ISLN 1502
>SPAC688.10 [L] KOG0968 DNA polymerase zeta catalytic subunit
Length = 1480
Score = 667 bits (1721), Expect = 0.0
Identities = 369/896 (41%), Positives = 542/896 (60%), Gaps = 30/896 (3%)
Query: 561 WKYIRPKPSFKRIANAMKPFKGKFSMVEGKTPELPFGYKFKSNKIEKNNNASNRMTHFTM 620
W+YI+P P ++N E + E+ + +K+ + + S + +
Sbjct: 606 WQYIKPAPLAVDLSN--------LESKEAVSEEIQSPQRLSRSKVFRKDPYSC-VRILAL 656
Query: 621 EIHVNTREDKFPDPKYDAVRMIFWKVQDGTFPFDLDITQEGVLIFLDDVSTENSWKTADP 680
E+ + PDP D++ FW Q+ +D I +D ++ +S+ + P
Sbjct: 657 ELFCCSHGGLTPDPTKDSIECCFWAYQEDVNSSMIDRVG---FIVVDKSASNSSFGRSFP 713
Query: 681 SVHITAYYDELEMIYALEDLVRFFDPDILSGYEIHSSSWGYLIDRCHKGHDYDVEDELSR 740
S + ELE+I + L R DP I+ GYE+H+SSWGYLI+R +YD+ ++LSR
Sbjct: 714 SCTVLVVNSELELINEVIGLNRQLDPTIVCGYEVHNSSWGYLIERASYRFNYDLPEQLSR 773
Query: 741 VDYNQSS---KKKDRWGYTHATAFSITGRQMLNIWRPLRSSLNLLDYTLENIAFHVLHQR 797
+ + KK++ W YT ++ +I GR +LNIWR LR +NLL+Y+LEN+ ++ ++
Sbjct: 774 LKCTSKANFAKKENAWKYTTTSSINIVGRHVLNIWRILRGEVNLLNYSLENVVLNIFKKQ 833
Query: 798 LPFYSYKTRTEFYESMDETSKRCLLFYWITRLRVNFKLLETQNIIGKTIEQARLIGIDFY 857
P+Y+ + ++S K+ LL Y + R R ++L I+ K EQAR+IGIDF
Sbjct: 834 TPYYNQADKVHLWQSSRFHEKQILLNYMLNRTRYCLEILSACAIVTKIREQARIIGIDFM 893
Query: 858 SVLYRGSQYKVESFLIRLCKSEQFILISPSRMQVRNQKALECIPLVMEPSSAFYKSPLLV 917
SV+ RGSQ+KVES + R+ K E +I SPS QV Q ALE +PLVMEP S Y +P++V
Sbjct: 894 SVISRGSQFKVESIMFRIAKPENYIFPSPSAKQVAEQNALEALPLVMEPKSDLYNNPVVV 953
Query: 918 LDFQSLYPSIVMAYNYCYSTIIGRVESLNTKNNEIGITRYDIPEDLLTLISDYITISPNG 977
LDFQSLYPSI++AYN CYST +G V+ +N K ++G + +++ LI + + ISPNG
Sbjct: 954 LDFQSLYPSIIIAYNLCYSTCLGPVKIVNGKV-KLGFMFHSSNPNIVNLIKNDVYISPNG 1012
Query: 978 IVFVKKELRKSVLAKMLKDILDTRFLMKSTMKELNDEHNLINMLDNRQEALKLLANVTYG 1037
+VK+ +RKS+LAKML+++++TR ++K MK+ + ++ + +L++RQ ALKL+ANVTYG
Sbjct: 1013 YAYVKENVRKSLLAKMLEELIETRNMVKRGMKDCDSDY-VNKVLNSRQLALKLIANVTYG 1071
Query: 1038 YTSASFSGRMPCSDIADSIVQTGRETLERAIEVIETTKEWGAKVVYGDTDSLFVYLPGKS 1097
YTSASFSGRMPCS+IAD+IV+TGRE L ++E I T AKVVYGDTDSLFV LPG +
Sbjct: 1072 YTSASFSGRMPCSEIADTIVETGREILSYSLEYINTLDFCHAKVVYGDTDSLFVELPGAT 1131
Query: 1098 KDEAFVIGRQIAEEITRQNPKPIELKFEKVYHPCFLVTKKRYVGFSYESEYQKEPKFDAK 1157
K++AF IG+Q+A IT + P PI LKFEK+Y PCFL+ KKRYVGF +ES QK P F+AK
Sbjct: 1132 KEQAFDIGQQLANNITSRFPSPIRLKFEKIYFPCFLLAKKRYVGFKFESVSQKAPIFEAK 1191
Query: 1158 GIETVRRDGTPAQQKIVEKALRIMFETTDLSMVKEYLIGEFDKIITGRVNIQDFCFAREV 1217
GIETVRRDGTP QQ+++ + L I+F+T DLS VK+ +I++G V + DFCF++EV
Sbjct: 1192 GIETVRRDGTPVQQQLLRRCLEILFKTKDLSTVKKEFQNVCYQIMSGNVPVMDFCFSKEV 1251
Query: 1218 KLGHYKSEKTAPPGAQIAMQMMEEDARTEPQYKQRVPYVVKMGKIGETLSSRCLSPEAFL 1277
+L YK TAPPGA +A ++M +D R EPQY +RVPY++ G TL++R ++PE FL
Sbjct: 1252 RLEKYKELSTAPPGAVMARRLMTKDPRREPQYGERVPYLIIAAAPGTTLANRSVAPEEFL 1311
Query: 1278 RSKTSRLDYTYYIVKNIIPPLQRFFQLVGVDIMDWYISMKHTLNPLKV-DSDDGSHEGRS 1336
S S+LD YYI ++IPPL RF L+G WY M LK+ ++ G + ++
Sbjct: 1312 SSSFSQLDINYYINNSLIPPLDRFLNLLGASAQSWYHEMPKPRTSLKLTETVKGGIQKKT 1371
Query: 1337 LTSIVKGKSCLRCRK---KVHPKFISPICGECRIDKSNTTLFLEESVRLKQSKMHSVMRT 1393
L + + K C C K ++ P I+ +C +C + T K+ +
Sbjct: 1372 LDTFLMEKLCSSCLKNNIEIIPDKINSLCSDCLKNPCATISKAVTQHNAYNKKLSLLFDI 1431
Query: 1394 CQTCSYKFHKDAMAPLDQIALKCQSKDCPVYFSKFKYMNGLK-DNDMRDLLMGLID 1448
C+ CS D + C+S C VY+ + K N K +M +G +D
Sbjct: 1432 CRGCSKLSSSDPVL--------CKSNSCKVYYDRAKTENYAKVQAEMLTKTLGSLD 1479
Score = 99.4 bits (246), Expect = 4e-20
Identities = 84/341 (24%), Positives = 137/341 (39%), Gaps = 56/341 (16%)
Query: 50 VPVLRFYGCLSTGHKVLIHCHGIFPYIFIKYDGHSNDKASVIRNRCTSLHKILETRMIET 109
VPV+R +G V H +FPYI+++Y A + L+T +
Sbjct: 36 VPVIRVFGLNEEAETVCCFIHNVFPYIYVEYSSF----AETLDLEVPDFLSQLQTSINYA 91
Query: 110 FTKTDFKEKLTSLKYIANVSVVKGVPFYGYHVGYEPYYKITLLNGSYSNKLSELLRDGRI 169
T + +V +VKG+PFYGY ++ + KI L + ++L +L R G I
Sbjct: 92 LALAARANPETYKPAVQSVQLVKGIPFYGYSFCFQKFLKICLFSPKNRDRLVDLFRQGAI 151
Query: 170 FTSKVDVFEAHIPYLLQMMADYNLFGCGWLKLSKCYFRQPVLLTDLDMNEILHTDSLERF 229
+ V+E+H+PYLLQ M D+NL+GC P+ DLD + I+ D L F
Sbjct: 152 LNKVIQVYESHLPYLLQFMVDHNLYGCA-----------PI---DLD-DSIIKRDDLLSF 196
Query: 230 LKKHLHPNQNVLDIDPFHRIGKTFLEMDIIPQFILNREEIQFRDLHHDFVELKKDLQTSD 289
+H + P ILN + R++H D E + +
Sbjct: 197 CNVEVH----------------------VSPNAILNACWLSERNIHTDLYE--THASSPN 232
Query: 290 QGYVNSTKDIWKEIQLLRKRKGLAEYEGLKEIFRESQLQYNWKEDERLVKHFDEAKKRMS 349
V S +IWK R+ L + + Q Q+ KE+ + R S
Sbjct: 233 SLLVTSLAEIWKS---EASRRNLTSSDETNSFSKLHQSQFGLKEE-------SSHEPRSS 282
Query: 350 SLFNKEKALN--FDNFVDPFINENFFASTKDALQELWPKIP 388
+ E A+ N + + + +T + + WP++P
Sbjct: 283 QHWKNEVAMKDLLKNLIKSKLESSSDVNT-PLIFDPWPELP 322
>Hs4506483 [L] KOG0968 DNA polymerase zeta catalytic subunit
Length = 3052
Score = 649 bits (1675), Expect = 0.0
Identities = 344/878 (39%), Positives = 524/878 (59%), Gaps = 40/878 (4%)
Query: 585 SMVEGKTPELPFGYKFKSNKIE--KNNNASNRMTHFTMEIHVNTREDKFPDPKYDAVRMI 642
S ++G + +G+K ++ K + +T ++E+H TR D PDP++D + +
Sbjct: 2187 SQIDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHARTRRDLEPDPEFDPICAL 2246
Query: 643 FWKVQDGTFPFDLDITQEGVLIFLDDVSTENSW----------KTADPSVHITAYYDELE 692
F+ + T D + T+ +I +D T S ++ + +T DE
Sbjct: 2247 FYCISSDTPLPDTEKTELTGVIVIDKDKTVFSQDIRYQTPLLIRSGITGLEVTYAADEKA 2306
Query: 693 MIYALEDLVRFFDPDILSGYEIHSSSWGYLIDRCHKGHDYDVEDELSRVD----YNQSSK 748
+ + + ++++ +DPDIL GYEI SWGYL+ R D+ +SRV N+ +
Sbjct: 2307 LFHEIANIIKRYDPDILLGYEIQMHSWGYLLQRA-AALSIDLCRMISRVPDDKIENRFAA 2365
Query: 749 KKDRWGYTHATAFSITGRQMLNIWRPLRSSLNLLDYTLENIAFHVLHQRLPFYSYKTRTE 808
++D +G + +I GR LN+WR +R+ + L +YT EN++FHVLHQR P ++++ ++
Sbjct: 2366 ERDEYGSYTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLSD 2425
Query: 809 FYESMDETSKRCLLFYWITRLRVNFKLLETQNIIGKTIEQARLIGIDFYSVLYRGSQYKV 868
++++ + + ++ ++++R+R N ++LE ++IGKT E ARL GI F VL RGSQY+V
Sbjct: 2426 WFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRV 2485
Query: 869 ESFLIRLCKSEQFILISPSRMQVRNQKALECIPLVMEPSSAFYKSPLLVLDFQSLYPSIV 928
ES ++R+ K +I ++PS Q +A +C+PL+MEP S FY + +LVLDFQSLYPSIV
Sbjct: 2486 ESMMLRIAKPMNYIPVTPSVQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIV 2545
Query: 929 MAYNYCYSTIIGRVESLNTKNN-EIGITRYDIPEDLLTLISDYITISPNGIVFVKKELRK 987
+AYNYC+ST +G VE+L + + G T +P DLL + IT+SPNG+ FVK +RK
Sbjct: 2546 IAYNYCFSTCLGHVENLGKYDEFKFGCTSLRVPPDLLYQVRHDITVSPNGVAFVKPSVRK 2605
Query: 988 SVLAKMLKDILDTRFLMKSTMKELNDEHNLINMLDNRQEALKLLANVTYGYTSASFSGRM 1047
VL +ML++IL TRF++K +MK + L MLD RQ LKL+ANVT+GYTSA+FSGRM
Sbjct: 2606 GVLPRMLEEILKTRFMVKQSMKAYKQDRALSRMLDARQLGLKLIANVTFGYTSANFSGRM 2665
Query: 1048 PCSDIADSIVQTGRETLERAIEVIETTKEWGAKVVYGDTDSLFVYLPGKSKDEAFVIGRQ 1107
PC ++ DSIV RETLERAI+++ TK+WGA+VVYGDTDS+FV L G +K+++F IG++
Sbjct: 2666 PCIEVGDSIVHKARETLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQE 2725
Query: 1108 IAEEITRQNPKPIELKFEKVYHPCFLVTKKRYVGFSYESEYQKEPKFDAKGIETVRRDGT 1167
IAE +T NPKP++LKFEKVY PC L TKKRYVG+ YE+ QK+P FDAKGIETVRRD
Sbjct: 2726 IAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSC 2785
Query: 1168 PAQQKIVEKALRIMFETTDLSMVKEYLIGEFDKIITGRVNIQDFCFAREVKLGHYKSEKT 1227
PA KI+E++L+++FET D+S++K+Y+ + K++ G+ +IQDF FA+E +
Sbjct: 2786 PAVSKILERSLKLLFETRDISLIKQYVQRQCMKLLEGKASIQDFIFAKEYRGSFSYKPGA 2845
Query: 1228 APPGAQIAMQMMEEDARTEPQYKQRVPYVVKMGKIGETLSSRCLSPEAFLRSKTSRLDYT 1287
P ++ +M+ D R+EPQ +RVPYV+ G G L P L+ T RL+ T
Sbjct: 2846 CVPALELTRKMLTYDRRSEPQVGERVPYVIIYGTPGVPLIQLVRRPVEVLQDPTLRLNAT 2905
Query: 1288 YYIVKNIIPPLQRFFQLVGVDIMDWYISMKHTLNPLKVDSDDGSHEGRSLTSIVKGKSCL 1347
YYI K I+PPL R F L+G+D+ WY + + +++ C
Sbjct: 2906 YYITKQILPPLARIFSLIGIDVFSWYHELPRIHKATSSSRSEPEGRKGTISQYFTTLHCP 2965
Query: 1348 RCRKKVHPKFISPICGECRIDKSNTTLFLEESVRLKQSKMHSVMRTCQTCSYKFHKDAMA 1407
C IC +CR + + L + +R + + +++ C+ C+ F +
Sbjct: 2966 VCDDLTQ----HGICSKCRSQPQHVAVILNQEIRELERQQEQLVKICKNCTGCFDRH--- 3018
Query: 1408 PLDQIALKCQSKDCPVYF---------SKFKYMNGLKD 1436
+ C S +CPV F SK Y+ L D
Sbjct: 3019 ------IPCVSLNCPVLFKLSRVNRELSKAPYLRQLLD 3050
Score = 75.5 bits (184), Expect = 6e-13
Identities = 36/89 (40%), Positives = 53/89 (59%)
Query: 120 TSLKYIANVSVVKGVPFYGYHVGYEPYYKITLLNGSYSNKLSELLRDGRIFTSKVDVFEA 179
++ +++ VS+V G+PFYGYH + KI L N + ++ ELL+ G I EA
Sbjct: 18 STAQHVFKVSLVSGMPFYGYHEKERHFMKIYLYNPTMVKRICELLQSGAIMNKFYQPHEA 77
Query: 180 HIPYLLQMMADYNLFGCGWLKLSKCYFRQ 208
HIPYLLQ+ DYNL+G + L+ FR+
Sbjct: 78 HIPYLLQLFIDYNLYGMNLINLAAVKFRK 106
>At1g67500 [L] KOG0968 DNA polymerase zeta catalytic subunit
Length = 1894
Score = 601 bits (1549), Expect = e-171
Identities = 354/929 (38%), Positives = 538/929 (57%), Gaps = 68/929 (7%)
Query: 549 LTSSGSVYARSRWKYIRPKPSFKRIANAMKPFKGKFSMVEGK------TPELPFGYKFKS 602
+ S + Y S ++PK +F + N + S + G TP G++ +
Sbjct: 972 VNSESNAYTESEID-LKPKGTFLNL-NLQASVSQELSQISGPDGKSGPTPLSQMGFRDPA 1029
Query: 603 NKIEKNNNASNRMTHFTMEIHVNTREDKFPDPKYDAVRMIFWKVQDGTFPFDLDITQEGV 662
+ A ++T ++E+H +R D PDP++D+V +I VQ+ D + + V
Sbjct: 1030 SM-----GAGQQLTILSIEVHAESRGDLRPDPRFDSVNVIALVVQND----DSFVAEVFV 1080
Query: 663 LIFLDDVSTENSWKTADPSVHITAYYDELEMI-YALEDLVRFFDPDILSGYEIHSSSWGY 721
L+F D S + ++ + +E ++ Y +E L ++ DPD+L G++I S G+
Sbjct: 1081 LLFSPD-SIDQRNVDGLSGCKLSVFLEERQLFRYFIETLCKW-DPDVLLGWDIQGGSIGF 1138
Query: 722 LIDRCHK-GHDY--DVEDELSRVDYNQSSKKK------------------------DRWG 754
L +R + G + ++ S N S K+ D WG
Sbjct: 1139 LAERAAQLGIRFLNNISRTPSPTTTNNSDNKRKLGNNLLPDPLVANPAQVEEVVIEDEWG 1198
Query: 755 YTHATAFSITGRQMLNIWRPLRSSLNLLDYTLENIAFHVLHQRLPFYSYKTRTEFYESMD 814
THA+ + GR +LN WR +R + L YT+E ++ VL Q++P YK TE++ S
Sbjct: 1199 RTHASGVHVGGRIVLNAWRLIRGEVKLNMYTIEAVSEAVLRQKVPSIPYKVLTEWFSSGP 1258
Query: 815 ETSKRCLLFYWITRLRVNFKLLETQNIIGKTIEQARLIGIDFYSVLYRGSQYKVESFLIR 874
++ + Y I R +N +++ ++I +T E AR+ GIDF+SVL RGSQY+VES L+R
Sbjct: 1259 AGARYRCIEYVIRRANLNLEIMSQLDMINRTSELARVFGIDFFSVLSRGSQYRVESMLLR 1318
Query: 875 LCKSEQFILISPSRMQVRNQKALECIPLVMEPSSAFYKSPLLVLDFQSLYPSIVMAYNYC 934
L ++ ++ ISP QV +Q A+EC+PLVMEP SAFY P++VLDFQSLYPS+++AYN C
Sbjct: 1319 LAHTQNYLAISPGNQQVASQPAMECVPLVMEPESAFYDDPVIVLDFQSLYPSMIIAYNLC 1378
Query: 935 YSTIIGRVESLNTKNNEIGITRYDIPEDLLTLISDYITISPNGIVFVKKELRKSVLAKML 994
+ST +G++ L K N +G++ Y + D+L ++ + +PN +++V E+R+ +L ++L
Sbjct: 1379 FSTCLGKLAHL--KMNTLGVSSYSLDLDVLQDLNQILQ-TPNSVMYVPPEVRRGILPRLL 1435
Query: 995 KDILDTRFLMKSTMKELNDEHNLINMLDN-RQEALKLLANVTYGYTSASFSGRMPCSDIA 1053
++IL TR ++K MK+L +++ + N RQ ALKL+ANVTYGYT+A FSGRMPC+++A
Sbjct: 1436 EEILSTRIMVKKAMKKLTPSEAVLHRIFNARQLALKLIANVTYGYTAAGFSGRMPCAELA 1495
Query: 1054 DSIVQTGRETLERAIEVIETTKEWGAKVVYGDTDSLFVYLPGKSKDEAFVIGRQIAEEIT 1113
DSIVQ GR TLE+AI + W A+VVYGDTDS+FV L G++ EAFV+G++IA IT
Sbjct: 1496 DSIVQCGRSTLEKAISFVNANDNWNARVVYGDTDSMFVLLKGRTVKEAFVVGQEIASAIT 1555
Query: 1114 RQNPKPIELKFEKVYHPCFLVTKKRYVGFSYESEYQKEPKFDAKGIETVRRDGTPAQQKI 1173
NP P+ LK EKVYHPCFL+TKKRYVG+SYES Q+EP FDAKGIETVRRD A K
Sbjct: 1556 EMNPHPVTLKMEKVYHPCFLLTKKRYVGYSYESPNQREPIFDAKGIETVRRDTCEAVAKT 1615
Query: 1174 VEKALRIMFETTDLSMVKEYLIGEFDKIITGRVNIQDFCFAREVKLGHYKSEKTA--PPG 1231
+E++LR+ FE ++S VK YL ++ +I++GRV++QDF FA+EV+LG Y + ++ PP
Sbjct: 1616 MEQSLRLFFEQKNISKVKSYLYRQWKRILSGRVSLQDFIFAKEVRLGTYSTRDSSLLPPA 1675
Query: 1232 AQIAMQMMEEDARTEPQYKQRVPYVVKMGKIGETLSSRCLSPEAFLRSKTS-RLDYTYYI 1290
A +A + M+ D RTEP+Y +RVPYVV G+ G L + P L T RL+ YYI
Sbjct: 1676 AIVATKSMKADPRTEPRYAERVPYVVIHGEPGARLVDMVVDPLVLLDVDTPYRLNDLYYI 1735
Query: 1291 VKNIIPPLQRFFQLVGVDIMDWYISM----KHTLNPLKVDSDDGSHEGRSLTSIVKGKSC 1346
K IIP LQR F LVG D+ W++ M + +L ++S + SH+ R + K C
Sbjct: 1736 NKQIIPALQRVFGLVGADLNQWFLEMPRLTRSSLGQRPLNSKN-SHKTR-IDYFYLSKHC 1793
Query: 1347 LRCRKKVHPKFISPICGECRIDKSNTTLFLEESVRLKQSKMHSVMRTCQTCSYKFHKDAM 1406
+ C + V + +C C +KS + + +M + C+ C
Sbjct: 1794 ILCGEVVQES--AQLCNRCLQNKSAAAATIVWKTSKLEREMQHLATICRHCG------GG 1845
Query: 1407 APLDQIALKCQSKDCPVYFSKFKYMNGLK 1435
+ Q +KC S C V++ + K L+
Sbjct: 1846 DWVVQSGVKCNSLACSVFYERRKVQKELR 1874
Score = 88.6 bits (218), Expect = 7e-17
Identities = 61/208 (29%), Positives = 93/208 (44%), Gaps = 13/208 (6%)
Query: 9 DSSLDSNEINIQINNSDSYQCFPTLLDCKTSKSLPGLRFVQVPVLRFYGCLSTGHKVLIH 68
DS SN +++I + D Y P S G +VPV+R YG G K +H
Sbjct: 3 DSQSGSNVFSLRIVSIDYYMASPIPGYNICYSSFQGSEVNEVPVIRIYGSTPAGQKTCLH 62
Query: 69 CHGIFPYIFIKYDGHSNDKASVIRNRCTSLHKILETRMIETFTKTDFKEKLTSLK-YIAN 127
H PY++I + + +L LE + K S + +I +
Sbjct: 63 IHRALPYLYIPCSEIPLEHHKGVDGSTLALSLELEKAL-------KLKGNAASKRQHIHD 115
Query: 128 VSVVKGVPFYGYHVGYEPYYKITLLNGSYSN-----KLSELLRDGRIFTSKVDVFEAHIP 182
+V+ FYGYH E + KI L S + + + LL G + + +E+HIP
Sbjct: 116 CEIVRAKKFYGYHSTEEAFVKIYLYPYSSYHPPDVARAASLLLAGAVLGKSLQPYESHIP 175
Query: 183 YLLQMMADYNLFGCGWLKLSKCYFRQPV 210
++LQ + DYNL+G G + +SK FR PV
Sbjct: 176 FILQFLVDYNLYGMGHVHISKMKFRSPV 203
>7304154 [L] KOG0968 DNA polymerase zeta catalytic subunit
Length = 1869
Score = 550 bits (1416), Expect = e-156
Identities = 315/840 (37%), Positives = 487/840 (57%), Gaps = 47/840 (5%)
Query: 596 FGYKFKSNKIE--KNNNASNRMTHFTMEIHVNTREDKFPDPKYDAVRMIFWKVQDGTFPF 653
FG+K ++ K + N +T T+E+ V+TR D PDP +D +R +F+ ++
Sbjct: 1044 FGFKVNLENLQQAKADIDCNHLTIITLEVFVSTRGDLQPDPMHDEIRCLFYAIEHSLPDE 1103
Query: 654 DLDITQEGVLIF--LDDVSTENSWKTADPSVHITAYYDELEMIYALEDLVRFFDPDILSG 711
L G ++ + D+ +E + D + + E E AL L +D DI +G
Sbjct: 1104 KLPSKACGYIMVNTVQDLLSEGPFHGIDRDIEVQVVTSEAEAFEALLALCERWDADIYAG 1163
Query: 712 YEIHSSSWGYLIDRCHKGHDYDVEDELSRVDYNQSSKKKDRWGYTHATAFSITGRQMLNI 771
YEI SSWGY+IDR K +++ LSRV + D
Sbjct: 1164 YEIEMSSWGYVIDRA-KHLCFNIAPLLSRVPTQKVRDFVDED------------------ 1204
Query: 772 WRPLRSSLNLLDYTLENIAFHVLHQRLPFYSYKTRTEFYESMDETSKRCLLFYWITRLRV 831
R LD ++ + +L R P+++ K+ TE++ S ++ ++ Y++ R+R
Sbjct: 1205 ----REQFTDLDVEMK-LCGRILLDRCPWHTAKSLTEWFGS--PCTRWIVMEYYLERVRG 1257
Query: 832 NFKLLETQNIIGKTIEQARLIGIDFYSVLYRGSQYKVESFLIRLCKSEQFILISPSRMQV 891
LL+ +++G+T E A+LIGI FY VL RGSQ++VES ++R+ K + + +SPS
Sbjct: 1258 TLTLLDQLDLLGRTSEMAKLIGIQFYEVLSRGSQFRVESMMLRIAKPKNLVPLSPSVQAR 1317
Query: 892 RNQKALECIPLVMEPSSAFYKSPLLVLDFQSLYPSIVMAYNYCYSTIIGRVESLNTKNN- 950
+ +A E + L+MEP S FY PL+VLDFQSLYPS+++AYNYC+ST +GRVE L +
Sbjct: 1318 AHMRAPEYLALIMEPQSRFYADPLIVLDFQSLYPSMIIAYNYCFSTCLGRVEHLGGSSPF 1377
Query: 951 EIGITRYDIPEDLLT--LISDYITISPNGIVFVKKELRKSVLAKMLKDILDTRFLMKSTM 1008
E G ++ + +L L D +T+SP G+VFVK+E+R+ +L +ML +ILDTR ++K +M
Sbjct: 1378 EFGASQLRVSRQMLQKLLEHDLVTVSPCGVVFVKREVREGILPRMLTEILDTRQMVKQSM 1437
Query: 1009 KELNDEHNLINMLDNRQEALKLLANVTYGYTSASFSGRMPCSDIADSIVQTGRETLERAI 1068
K D L +L +RQ LKL+ANVTYGYT+A+FSGRMP ++ DS+V GRETLERAI
Sbjct: 1438 KLHKDSSALQRILHSRQLGLKLMANVTYGYTAANFSGRMPSVEVGDSVVSKGRETLERAI 1497
Query: 1069 EVIETTKEWGAKVVYGDTDSLFVYLPGKSKDEAFVIGRQIAEEITRQNPKPIELKFEKVY 1128
+++E +EW +VVYGDTDS+FV +PG+++ EAF IG +IA+ +T NP+P++LK EKVY
Sbjct: 1498 KLVENNEEWKVRVVYGDTDSMFVLVPGRNRAEAFRIGEEIAKAVTEMNPQPVKLKLEKVY 1557
Query: 1129 HPCFLVTKKRYVGFSYESEYQKEPKFDAKGIETVRRDGTPAQQKIVEKALRIMFETTDLS 1188
PC L TKKRYVG+ YE+ Q++P ++AKGIETVRRDG PA K++EK LRI+FET D+S
Sbjct: 1558 QPCMLQTKKRYVGYMYETADQEQPVYEAKGIETVRRDGCPAVAKMLEKVLRILFETQDVS 1617
Query: 1189 MVKEYLIGEFDKIITGRVNIQDFCFAREVK-LGHYKSEKTAPPGAQIAMQMMEEDARTEP 1247
+K Y+ +F K+++GR N+QD FA+E + L YK P ++ + M++D R P
Sbjct: 1618 KIKAYVCRQFTKLLSGRANLQDLIFAKEFRGLNGYK-PTACVPALELTRKWMQKDPRHVP 1676
Query: 1248 QYKQRVPYVVKMGKIGETLSSRCLSPEAFLRSKTSRLDYTYYIVKNIIPPLQRFFQLVGV 1307
+ +RVP+++ G G L SP L ++ +++ YYI K IIPPL R L+G
Sbjct: 1677 RRGERVPFIIVNGPPGMQLIRLVRSPHDILANEGHKINAIYYITKAIIPPLNRCLLLIGA 1736
Query: 1308 DIMDWYISM--KHTLNPLKVDSDDGSHEGRSLTSIVKGKSCLRCRKKVHPKFISPICGEC 1365
++ DW+ S+ K + P +++ + + ++I + S C + + IC +C
Sbjct: 1737 NVHDWFASLPRKLLMTPAVGTANELAGARGAKSTISQYFSTTSCVIDCGRQTKAGICPDC 1796
Query: 1366 RIDKSNTTLFLEESVRLKQSKMHSVMRTCQTCSYKFHKDAMAPLDQIALKCQSKDCPVYF 1425
+ + + L + + + CQ C + +L+C S DCPV +
Sbjct: 1797 LKNATTCVVVLSDKTARLERGYQLTRQICQACCGRLG----------SLQCDSLDCPVLY 1846
Score = 104 bits (260), Expect = 9e-22
Identities = 66/229 (28%), Positives = 109/229 (46%), Gaps = 42/229 (18%)
Query: 42 LPGLRFVQVPVLRFYGCLSTGHKVLIHCHGIFPYIFIKYDGHSNDKASVIRNRCTSLHKI 101
L G +VPV+R +G S G K +H HG+FPY++I YD D S+ R I
Sbjct: 37 LRGKEIKRVPVIRVFGGNSRGQKTCMHVHGVFPYLYIPYD--KKDFESLERG-------I 87
Query: 102 LETRM-IETFTKTDFKEKLTSLKYIANVSVVKGVPFYGYHVGYEPYYKITLLNGSYSNKL 160
L+ M ++ + ++ +++ + +VKG+PFYGYH + KI + N + +
Sbjct: 88 LQMAMHLDKAINISLGQGSSNAQHVFKIQLVKGIPFYGYHRVEHQFLKIYMFNPRFVRRA 147
Query: 161 SELLRDGRIFTSKVDVFEAHIPYLLQMMADYNLFGCGWLKLSKCYFRQPVLLTDLDMNEI 220
+ LL+ G I + E+H+PY+LQ M DYNL+G ++ +
Sbjct: 148 ANLLQSGAILSKNFSPHESHVPYILQFMIDYNLYGMSYVHV------------------- 188
Query: 221 LHTDSLERFLKKHLHPNQNVLDIDPFHRIGKTFLEMDIIPQFILNREEI 269
LE+ +LDI ++ + LE+D+ FILNR ++
Sbjct: 189 ----PLEQ---------AQLLDITTAKKVACSALEVDVSSNFILNRFQL 224
>CE27403 [L] KOG0968 DNA polymerase zeta catalytic subunit
Length = 1154
Score = 365 bits (938), Expect = e-100
Identities = 230/632 (36%), Positives = 354/632 (55%), Gaps = 25/632 (3%)
Query: 690 ELEMIYALEDLVRFFDPDILSGYEIHSSSWGYLIDRCHKGHDYDVEDELSRVDYNQSSKK 749
ELEM+ + + +D D++ GYE SWG+ R K + + + +D + +
Sbjct: 434 ELEMLEEVAKWIVQYDVDVMIGYETIRLSWGFFFRRI-KLLGSRISMDRALIDAYEDHIE 492
Query: 750 KDRWGYTHATAFSITGRQMLNIWRPLRSSLNLLDYTLENIAFHVLHQRLPFYSYKTRTEF 809
D T A GR ++++W+ +RS L L +Y L + +VL +++P
Sbjct: 493 VDDQEITVAPP---KGRLLVSVWKVVRSDLALRNYDLGSAVANVLRKKIPMLDNAALMRR 549
Query: 810 YESMDETSKRCLLFYWITRLRVNFKLLETQNIIGKTIEQARLIGIDFYSVLYRGSQYKVE 869
+ + + + + +N LL N K E AR+ GI F+ V RGSQ +VE
Sbjct: 550 IKGERSAIRNDVHLHLLKLSSLNISLLTEMNWFLKNAEMARVYGIQFHEVWTRGSQLRVE 609
Query: 870 SFLIRLCKSEQFILISPSRMQVRNQKALECIPLVMEPSSAFYKSPLLVLDFQSLYPSIVM 929
S L+RL F+ S + +Q + E + L++EP S Y P++VLDFQSLYPS+V+
Sbjct: 610 SMLLRLAHRMNFVAPSITHLQRNMMGSPEQLQLILEPQSKVYFDPVIVLDFQSLYPSMVI 669
Query: 930 AYNYCYSTIIGRVESLNTKNNE--------IGITRYDIPEDLLTLISDY--ITISPNGIV 979
AYNYCYSTI+G++ +L N+E +G +Y +D + + Y + SP +
Sbjct: 670 AYNYCYSTILGKIGNLVQMNDESRNREEIVLGAIKYHPSKDDIVKLVAYKEVCASPLASM 729
Query: 980 FVKKELRKSVLAKMLKDILDTRFLMKSTMKELNDEHNLINMLDNRQEALKLLANVTYGYT 1039
FVKK R+ V+ +L++IL R ++KS MK ++ L +LD RQ ALKL+ANV+YGYT
Sbjct: 730 FVKKSKREGVMPLLLREILAARIMVKSAMKRTKNK-KLKRILDARQLALKLVANVSYGYT 788
Query: 1040 SASFSGRMPCSDIADSIVQTGRETLERAIEVIETTKEWGAKVVYGDTDSLFVYLPGKSKD 1099
+A++SGRMPC+++AD+I+ GRETLER+IE+++ GA+V+YGDTDS+FV + G S +
Sbjct: 789 AANWSGRMPCAELADAILGKGRETLERSIEMVQRGDYGGAEVIYGDTDSMFVLVRGASVE 848
Query: 1100 EAFVIGRQIAEEITRQNPKPIELKFEKVYHPCFLVTKKRYVGFSYESEYQKEPKFDAKGI 1159
EAF IGR+I +++T NP P+ LK EKVY C L TKKRY G+ YE E E DAKGI
Sbjct: 849 EAFEIGRRIVDDVTNSNPDPVVLKLEKVYKGCVLETKKRYAGWMYEHE-NDEGSLDAKGI 907
Query: 1160 ETVRRDGTPAQQKIVEKALRIMFETTDLSMVKEYLIGEFDKIITG--RVNIQDFCFAREV 1217
ETVRRD P +++EK+L ++F S + I + ++ + N F F +E
Sbjct: 908 ETVRRDTCPIVAEVLEKSLGLIF-----SQNWKTFITYLNTVVLNLPQENFSKFVFCKEY 962
Query: 1218 KLGHYKSEKTAPPGAQIAMQMMEEDARTEPQYKQRVPYVVKMGKIGETLSSRCLSPEAFL 1277
+ G Y S + P +IA + + +RVPYV+ G G T+ S S + F
Sbjct: 963 R-GDY-SARAMVPQKKIAEARIRKCPSHITLRGERVPYVIIDGVTGSTVYSCVRSIDQFA 1020
Query: 1278 RSKTSRLDYTYYIVKNIIPPLQRFFQLVGVDI 1309
R+ +++ YY+ +I+ L+R L+ + I
Sbjct: 1021 RNPEYKINTFYYLNAHILAALRRVTDLIPMKI 1052
>7294203 [L] KOG0969 DNA polymerase delta catalytic subunit
Length = 1092
Score = 290 bits (743), Expect = 9e-78
Identities = 235/845 (27%), Positives = 388/845 (45%), Gaps = 66/845 (7%)
Query: 619 TMEIHVNTREDKFPDPKYDAVRMIFWKVQDGTFPFDLDITQEGVLIFLDDVSTENSWKTA 678
+ +I R+ FP+ K D V I ++ I Q F+ +V T N
Sbjct: 298 SFDIECAGRKGIFPEAKIDPVIQIA----------NMVIRQGEREPFIRNVFTLNECAPI 347
Query: 679 DPSVHITAYYDELEMIYALEDLVRFFDPDILSGYEIHSSSWGYLIDRCH----KGHDYDV 734
S + + E +M+ VR DPDIL+GY I++ + YL++R + +Y
Sbjct: 348 IGS-QVLCHDKETQMLDKWSAFVREVDPDILTGYNINNFDFPYLLNRAAHLKVRNFEYLG 406
Query: 735 EDELSRVDYNQSSKKKDRWGYTHATAFSITGRQMLNIWRPLRSSLNLLDYTLENIAFHVL 794
+ R + + + G + GR ++ L L YTL +++H L
Sbjct: 407 RIKNIRSVIKEQMLQSKQMGRRENQYVNFEGRVPFDLLFVLLRDYKLRSYTLNAVSYHFL 466
Query: 795 HQRLPFYSYKTRTEFYESMDETSKRCLLFYWITRLRVNFKLLETQNIIGKTIEQARLIGI 854
++ + T+ ++ DE ++R L Y + + +LLE I +E AR+ G+
Sbjct: 467 QEQKEDVHHSIITDL-QNGDEQTRRRLAMYCLKDAYLPLRLLEKLMAIVNYMEMARVTGV 525
Query: 855 DFYSVLYRGSQYKVESFLIRLCKSEQFILISPSRMQVRNQKALECIPLVMEPSSAFYKSP 914
S+L RG Q KV S L+R K++ FI+ PS + + E V+EP +Y P
Sbjct: 526 PLESLLTRGQQIKVLSQLLRKAKTKGFIM--PSYTSQGSDEQYEGAT-VIEPKRGYYADP 582
Query: 915 LLVLDFQSLYPSIVMAYNYCYSTII--GRVESLNTKNNEIGITRYDIPEDLLTLISDYIT 972
+ LDF SLYPSI+MA+N CY+T++ G E L + N L D +
Sbjct: 583 ISTLDFASLYPSIMMAHNLCYTTLVLGGTREKLRQQEN---------------LQDDQVE 627
Query: 973 ISPNGIVFVKKELRKSVLAKMLKDILDTRFLMKSTMKELNDEHNLINMLDNRQEALKLLA 1032
+P FVK E+R+ +L ++L+ +L R K+ +K D +LD RQ ALK+ A
Sbjct: 628 RTPANNYFVKSEVRRGLLPEILESLLAARKRAKNDLKVETDPFKR-KVLDGRQLALKISA 686
Query: 1033 NVTYGYTSASFSGRMPCSDIADSIVQTGRETLERAIEVIETTK------EWGAKVVYGDT 1086
N YG+T A G++PC +I+ S+ GR +E +E+ E A V+YGDT
Sbjct: 687 NSVYGFTGAQV-GKLPCLEISGSVTAYGRTMIEMTKNEVESHYTQANGYENNAVVIYGDT 745
Query: 1087 DSLFVYLPGKSKDEAFVIGRQIAEEITRQNPKPIELKFEKVYHPCFLVTKKRYVGFSYES 1146
DS+ V K+ + + +GR+ AE ++ + PI+L+FEKVY+P L+ KKRY G Y +
Sbjct: 746 DSVMVNFGVKTLERSMELGREAAELVSSKFVHPIKLEFEKVYYPYLLINKKRYAGL-YFT 804
Query: 1147 EYQKEPKFDAKGIETVRRDGTPAQQKIVEKALRIMFETTDLSMVKEYLIGEFDKIITGRV 1206
K D KGIETVRRD +P ++ L+ + D Y+ ++ R+
Sbjct: 805 RPDTYDKMDCKGIETVRRDNSPLVANLMNSCLQKLLIERDPDGAVAYVKQVIADLLCNRI 864
Query: 1207 NIQDFCFAREVKLGHYKSEKTAPPGAQIAMQMMEEDARTEPQYKQRVPYVVKMGKIGETL 1266
+I +E+ Y +++ ++A +M + D T P+ RVPYV+
Sbjct: 865 DISHLVITKELAKTDYAAKQA---HVELAAKMKKRDPGTAPKLGDRVPYVICAAAKNTPA 921
Query: 1267 SSRCLSPEAFLRSKTSRLDYTYYIVKNIIPPLQRFFQ-LVGVDIMDWYISMKHTLNPLKV 1325
+ P ++ + +D TYY+ + + PL R F+ ++G + + +HT V
Sbjct: 922 YQKAEDP-LYVLENSVPIDATYYLEQQLSKPLLRIFEPILGDNAESILLKGEHTRTRTVV 980
Query: 1326 DSDDGSHEGRSLTSIVKGKSCLRCRKKVHPKFISPICGECRIDKSNTTLFLEE--SVRLK 1383
S G G + K SCL C K + PK C + + L+ +E + R
Sbjct: 981 TSKVGGLAG----FMTKKTSCLGC-KSLMPKGYEQACLCPHCEPRMSELYQKEVGAKREL 1035
Query: 1384 QSKMHSVMRTCQTCSYKFHKDAMAPLDQIALKCQSKDCPVYFSKFKYMNGLKDNDMRDLL 1443
+ + CQ C H++ + C ++DCP+++ + K L + + R L
Sbjct: 1036 EETFSRLWTECQRCQESLHEEVI---------CSNRDCPIFYMRQKVRMDLDNQEKRVLR 1086
Query: 1444 MGLID 1448
GL +
Sbjct: 1087 FGLAE 1091
Score = 61.6 bits (148), Expect = 9e-09
Identities = 43/172 (25%), Positives = 80/172 (46%), Gaps = 17/172 (9%)
Query: 42 LPGLRFVQVPVLRFYGCLSTGHKVLIHCHGIFPYIFIKYDGHSNDKASVIRNRCTSLHKI 101
+PG + VPV+R +G G+ V H HG PY +I+ + + C L K
Sbjct: 94 MPGAQIGPVPVVRMFGVTMEGNSVCCHVHGFCPYFYIEAPSQFEE------HHCEKLQKA 147
Query: 102 LETRMIETFTKTDFKEKLTSLKYIANVSVVKGVPFYGYHVG-YEPYYKITLLNGSYSNKL 160
L+ ++I K + + V +V+ + +GY+ + Y KI++ +
Sbjct: 148 LDQKVIADIR----NNKDNVQEAVLMVELVEKLNIHGYNGDKKQRYIKISVTLPRFVAAA 203
Query: 161 SELLRDGRIFTSKVD-----VFEAHIPYLLQMMADYNLFGCGWLKLSKCYFR 207
S LL+ + S++D FE +I + ++ M D ++ GC W++L ++R
Sbjct: 204 SRLLKK-EVIMSEIDFQDCRAFENNIDFDIRFMVDTDVVGCNWIELPMGHWR 254
>SPBC336.04 [L] KOG0969 DNA polymerase delta catalytic subunit
Length = 1086
Score = 278 bits (711), Expect = 5e-74
Identities = 229/826 (27%), Positives = 381/826 (45%), Gaps = 76/826 (9%)
Query: 619 TMEIHVNTREDKFPDPKYDAV---RMIFWKVQDGTFPFDLDITQEGVLIFLDDVSTENSW 675
+ +I R+ FPDP D V I + D T PF ++ F D ++
Sbjct: 298 SFDIECAGRKGVFPDPSIDPVIQIASIVTQYGDST-PFVRNV-------FCVDTCSQIV- 348
Query: 676 KTADPSVHITAYYDELEMIYALEDLVRFFDPDILSGYEIHSSSWGYLIDRCH--KGHDYD 733
+ + ++ EM+ + VR DPD+L GY I + YL+DR + H++
Sbjct: 349 -----GTQVYEFQNQAEMLSSWSKFVRDVDPDVLIGYNICNFDIPYLLDRAKSLRIHNFP 403
Query: 734 VEDELSRVDYNQSSKKKDR------WGYTHATAFSITGRQMLNIWRPLRSSLNLLDYTLE 787
+ L R+ +N S K+ +G + SI GR L++ + ++ L Y+L
Sbjct: 404 L---LGRI-HNFFSVAKETTFSSKAYGTRESKTTSIPGRLQLDMLQVMQRDFKLRSYSLN 459
Query: 788 NIAFHVLHQRLPFYSYKTRTEFYESMDETSKRCLLFYWITRLRVNFKLLETQNIIGKTIE 847
+ L ++ Y T+ + S+R L Y + + +L++ E
Sbjct: 460 AVCSQFLGEQKEDVHYSIITDLQNGTAD-SRRRLAIYCLKDAYLPQRLMDKLMCFVNYTE 518
Query: 848 QARLIGIDFYSVLYRGSQYKVESFLIRLCKSEQFILISPSRMQVRNQKALECIPLVMEPS 907
AR+ G+ F +L RG Q KV S L R K+ Q L+ P+ ++V V+EP
Sbjct: 519 MARVTGVPFNFLLARGQQIKVISQLFR--KALQHDLVVPN-IRVNGTDEQYEGATVIEPI 575
Query: 908 SAFYKSPLLVLDFQSLYPSIVMAYNYCYSTIIGRVESLNTKNNEIGITRYDIPEDLLTLI 967
+Y +P+ LDF SLYPSI+ A+N CY+T+ L++ E+ + D+
Sbjct: 576 KGYYDTPIATLDFSSLYPSIMQAHNLCYTTL------LDSNTAELLKLKQDV-------- 621
Query: 968 SDYITISPNGIVFVKKELRKSVLAKMLKDILDTRFLMKSTMKELNDEHNLINMLDNRQEA 1027
DY +++PNG FVK +RK +L +L D+L+ R K+ +K+ D +LD RQ A
Sbjct: 622 -DY-SVTPNGDYFVKPHVRKGLLPIILADLLNARKKAKADLKKETDPFKKA-VLDGRQLA 678
Query: 1028 LKLLANVTYGYTSASFSGRMPCSDIADSIVQTGRETLERAIEV------IETTKEWGAKV 1081
LK+ AN YG+T A+ +GR+PC I+ S+ GR+ +E+ +V IE A V
Sbjct: 679 LKVSANSVYGFTGAT-NGRLPCLAISSSVTSYGRQMIEKTKDVVEKRYRIENGYSHDAVV 737
Query: 1082 VYGDTDSLFVYLPGKSKDEAFVIGRQIAEEITRQNPKPIELKFEKVYHPCFLVTKKRYVG 1141
+YGDTDS+ V K+ EA +G + A ++ Q P PI+L+FEKVY P L++KKRY G
Sbjct: 738 IYGDTDSVMVKFGVKTLPEAMKLGEEAANYVSDQFPNPIKLEFEKVYFPYLLISKKRYAG 797
Query: 1142 FSYESEYQKEPKFDAKGIETVRRDGTPAQQKIVEKALRIMFETTDLSMVKEYLIGEFDKI 1201
+ + K D+KGIETVRRD P +++ ALR M D+ + + +
Sbjct: 798 L-FWTRTDTYDKMDSKGIETVRRDNCPLVSYVIDTALRKMLIDQDVEGAQLFTKKVISDL 856
Query: 1202 ITGRVNIQDFCFAREVKLGHYKSEKTAPPGAQIAMQMMEEDARTEPQYKQRVPYVVKMGK 1261
+ ++++ + + Y ++ ++A +M + DA + P RV YV+ G
Sbjct: 857 LQNKIDMSQLVITKALSKTDYAAKMA---HVELAERMRKRDAGSAPAIGDRVAYVIIKGA 913
Query: 1262 IGETLSSRCLSPEAFLRSKTSRLDYTYYIVKNIIPPLQRFFQLVGVDIMDWYISMKHTLN 1321
G+ R P ++ +D YY+ + PL R F+ + + + HT
Sbjct: 914 QGDQFYMRSEDP-IYVLENNIPIDAKYYLENQLSKPLLRIFEPILGEKASSLLHGDHT-- 970
Query: 1322 PLKVDSDDGSHEGRSLTSIVKGKSCLRCRKKVHPKFISPICGECRIDKSNTTLFLEESVR 1381
+ S G + VK ++CL C+ + K + +C C + V
Sbjct: 971 --RTISMAAPSVGGIMKFAVKVETCLGCKAPI-KKGKTALCENCLNRSAELYQRQVAQVN 1027
Query: 1382 LKQSKMHSVMRTCQTCSYKFHKDAMAPLDQIALKCQSKDCPVYFSK 1427
+ + + CQ C H+D + C S+DCP+++ +
Sbjct: 1028 DLEVRFARLWTQCQRCQGSMHQDVI---------CTSRDCPIFYMR 1064
>At5g63960 [L] KOG0969 DNA polymerase delta catalytic subunit
Length = 1081
Score = 277 bits (709), Expect = 8e-74
Identities = 214/707 (30%), Positives = 343/707 (48%), Gaps = 66/707 (9%)
Query: 619 TMEIHVNTREDKFPDPKYDAVRMI--FWKVQDGTFPFDLDITQEGVLIFLDDVSTENSWK 676
+ +I R+ FP+ K+D V I +Q PF V + K
Sbjct: 308 SFDIECAGRKGHFPEAKHDPVIQIANLVTLQGEDHPF---------------VRNVMTLK 352
Query: 677 TADP--SVHITAYYDELEMIYALEDLVRFFDPDILSGYEIHSSSWGYLIDRCHKGHDYDV 734
+ P V + ++ E E++ A DL+R DPDI+ GY I YLI+R +
Sbjct: 353 SCAPIVGVDVMSFETEREVLLAWRDLIRDVDPDIIIGYNICKFDLPYLIERAAT---LGI 409
Query: 735 ED-------ELSRVDYNQSSKKKDRWGYTHATAFSITGRQMLNIWRPLRSSLNLLDYTLE 787
E+ + SRV S+ + G + +I GR ++ + + L Y+L
Sbjct: 410 EEFPLLGRVKNSRVRVRDSTFSSRQQGIRESKETTIEGRFQFDLIQAIHRDHKLSSYSLN 469
Query: 788 NIAFHVLHQRLPFYSYKTRTEFYESMDETSKRCLLFYWITRLRVNFKLLETQNIIGKTIE 847
+++ H L ++ + T+ ET +R L Y + + +LL+ I +E
Sbjct: 470 SVSAHFLSEQKEDVHHSIITDLQNGNAETRRR-LAVYCLKDAYLPQRLLDKLMFIYNYVE 528
Query: 848 QARLIGIDFYSVLYRGSQYKVESFLIRLCKSEQFILISPSRMQVRNQKALECIPLVMEPS 907
AR+ G+ +L RG KV S L+R K +Q L+ P+ Q +++ V+E
Sbjct: 529 MARVTGVPISFLLARGQSIKVLSQLLR--KGKQKNLVLPNAKQSGSEQGTYEGATVLEAR 586
Query: 908 SAFYKSPLLVLDFQSLYPSIVMAYNYCYSTIIGRVESLNTKNNEIGITRYDIPEDL--LT 965
+ FY+ P+ LDF SLYPSI+MAYN CY T++ PED+ L
Sbjct: 587 TGFYEKPIATLDFASLYPSIMMAYNLCYCTLV-------------------TPEDVRKLN 627
Query: 966 LISDYITISPNGIVFVKKELRKSVLAKMLKDILDTRFLMKSTMKELNDEHNLINMLDNRQ 1025
L +++T +P+G FVK+ L+K +L ++L+++L R K+ +KE D +LD RQ
Sbjct: 628 LPPEHVTKTPSGETFVKQTLQKGILPEILEELLTARKRAKADLKEAKDPLEKA-VLDGRQ 686
Query: 1026 EALKLLANVTYGYTSASFSGRMPCSDIADSIVQTGRETLERAIEVIE---TTK---EWGA 1079
ALK+ AN YG+T A+ G++PC +I+ S+ GR+ +E+ +++E TT ++ A
Sbjct: 687 LALKISANSVYGFTGATV-GQLPCLEISSSVTSYGRQMIEQTKKLVEDKFTTLGGYQYNA 745
Query: 1080 KVVYGDTDSLFVYLPGKSKDEAFVIGRQIAEEITRQNPKPIELKFEKVYHPCFLVTKKRY 1139
+V+YGDTDS+ V + A +GR+ AE I+ KPI+L+FEKVY P L+ KKRY
Sbjct: 746 EVIYGDTDSVMVQFGVSDVEAAMTLGREAAEHISGTFIKPIKLEFEKVYFPYLLINKKRY 805
Query: 1140 VGFSYESEYQKEPKFDAKGIETVRRDGTPAQQKIVEKALRIMFETTDLSMVKEYLIGEFD 1199
G + + Q + K D KGIETVRRD + +V ++L + D+ E +
Sbjct: 806 AGLLWTNPQQFD-KMDTKGIETVRRDNCLLVKNLVTESLNKILIDRDVPGAAENVKKTIS 864
Query: 1200 KIITGRVNIQDFCFAREV-KLGHYKSEKTAPPGAQIAMQMMEEDARTEPQYKQRVPYVVK 1258
++ R+++ + + K G K+A ++A +M + DA T P RVPYV+
Sbjct: 865 DLLMNRIDLSLLVITKGLTKTGDDYEVKSA--HGELAERMRKRDAATAPNVGDRVPYVII 922
Query: 1259 MGKIGETLSSRCLSPEAFLRSKTSRLDYTYYIVKNIIPPLQRFFQLV 1305
G R P L++ +D YY+ I PL R F+ V
Sbjct: 923 KAAKGAKAYERSEDPIYVLQNNIP-IDPNYYLENQISKPLLRIFEPV 968
>Hs4505933 [L] KOG0969 DNA polymerase delta catalytic subunit
Length = 1107
Score = 276 bits (706), Expect = 2e-73
Identities = 211/775 (27%), Positives = 359/775 (46%), Gaps = 69/775 (8%)
Query: 684 ITAYYDELEMIYALEDLVRFFDPDILSGYEIHSSSWGYLIDRCH--KGHDYDVEDELSRV 741
+ +Y E +++ A +R DPD+++GY I + YLI R K + ++ +
Sbjct: 368 VQSYEKEEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVQTFPFLGRVAGL 427
Query: 742 DYN--QSSKKKDRWGYTHATAFSITGRQMLNIWRPLRSSLNLLDYTLENIAFHVLHQRLP 799
N SS + + G S+ GR +++ + L L +TL ++FH L ++
Sbjct: 428 CSNIRDSSFQSKQTGRRDTKVVSMVGRVQMDMLQVLLREYKLRSHTLNAVSFHFLGEQKE 487
Query: 800 FYSYKTRTEFYESMDETSKRCLLFYWITRLRVNFKLLETQNIIGKTIEQARLIGIDFYSV 859
+ T+ D+T +R L Y + + +LLE ++ +E AR+ G+ +
Sbjct: 488 DVQHSIITDLQNGNDQTRRR-LAVYCLKDAYLPLRLLERLMVLVNAVEMARVTGVPLSYL 546
Query: 860 LYRGSQYKVESFLIRLCKSEQFILISPSRMQVRNQKALECI-PLVMEPSSAFYKSPLLVL 918
L RG Q KV S L+R E ++ V+++ + V+EP +Y P+ L
Sbjct: 547 LSRGQQVKVVSQLLRQAMHEGLLM-----PVVKSEGGEDYTGATVIEPLKGYYDVPIATL 601
Query: 919 DFQSLYPSIVMAYNYCYSTII--GRVESLNTKNNEIGITRYDIPEDLLTLISDYITISPN 976
DF SLYPSI+MA+N CY+T++ G + L L D +P
Sbjct: 602 DFSSLYPSIMMAHNLCYTTLLRPGTAQKLG-------------------LTEDQFIRTPT 642
Query: 977 GIVFVKKELRKSVLAKMLKDILDTRFLMKSTMKELNDEHNLINMLDNRQEALKLLANVTY 1036
G FVK +RK +L ++L+++L R K+ + + D +LD RQ ALK+ AN Y
Sbjct: 643 GDEFVKTSVRKGLLPQILENLLSARKRAKAELAKETDPLRR-QVLDGRQLALKVSANSVY 701
Query: 1037 GYTSASFSGRMPCSDIADSIVQTGRETLERAIEVIET--TKEWG----AKVVYGDTDSLF 1090
G+T A G++PC +I+ S+ GR+ +E+ +++E+ T E G AKVVYGDTDS+
Sbjct: 702 GFTGAQV-GKLPCLEISQSVTGFGRQMIEKTKQLVESKYTVENGYSTSAKVVYGDTDSVM 760
Query: 1091 VYLPGKSKDEAFVIGRQIAEEITRQNPKPIELKFEKVYHPCFLVTKKRYVGFSYESEYQK 1150
S EA +GR+ A+ ++ P PI L+FEKVY P L++KKRY G + S
Sbjct: 761 CRFGVSSVAEAMALGREAADWVSGHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDA 820
Query: 1151 EPKFDAKGIETVRRDGTPAQQKIVEKALRIMFETTDLSMVKEYLIGEFDKIITGRVNIQD 1210
+ D KG+E VRRD P +V +LR + D + ++ R++I
Sbjct: 821 HDRMDCKGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVISDLLCNRIDISQ 880
Query: 1211 FCFAREV--KLGHYKSEKTAPPGAQIAMQMMEEDARTEPQYKQRVPYVVKMGKIGETLSS 1268
+E+ Y ++ ++A +M + D + P RVPYV+ G
Sbjct: 881 LVITKELTRAASDYAGKQA---HVELAERMRKRDPGSAPSLGDRVPYVIISAAKGVAAYM 937
Query: 1269 RCLSPEAFLRSKTSRLDYTYYIVKNIIPPLQRFFQLVGVDIMDWYISMK--HTLNPLKVD 1326
+ P F+ + +D YY+ + + PL R F+ + + + ++ HT +
Sbjct: 938 KSEDP-LFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAEAVLLRGDHTRCKTVLT 996
Query: 1327 SDDGSHEGRSLTSIVKGKS-CLRCRKKVHPKFISPICGECRIDKSNTTLFLEESVRLK-- 1383
G L + K ++ C+ CR + + +C C+ +S L+ +E L
Sbjct: 997 GKVG-----GLLAFAKRRNCCIGCRTVLSHQ--GAVCEFCQPRESE--LYQKEVSHLNAL 1047
Query: 1384 QSKMHSVMRTCQTCSYKFHKDAMAPLDQIALKCQSKDCPVYFSKFKYMNGLKDND 1438
+ + + CQ C H+D + C S+DCP+++ + K L+D +
Sbjct: 1048 EERFSRLWTQCQRCQGSLHEDVI---------CTSRDCPIFYMRKKVRKDLEDQE 1093
>ECU09g0430 [L] KOG0969 DNA polymerase delta catalytic subunit
Length = 974
Score = 261 bits (667), Expect = 6e-69
Identities = 200/766 (26%), Positives = 355/766 (46%), Gaps = 68/766 (8%)
Query: 677 TADPSVHITAYYDELEMIYALEDLVRFFDPDILSGYEIHSSSWGYLIDRCHKGHDYDVED 736
T P V++ Y E E++ + + DPD++ GY + Y++ R G +E
Sbjct: 244 TGIPGVNVHWYETEKELLESWKKYFMELDPDVIVGYNVKGFDIPYILSR---GEILGIES 300
Query: 737 ------ELSRVDYNQSSKKKDRWGYTHATAFSITGRQMLNIWRPLRSSLNLLDYTLENIA 790
+ ++ + +G T I GR ++++ +R L Y+L +++
Sbjct: 301 FSVLGRSRKKARTRDTTMSSNMFGSITTTEVEIDGRLIIDMMVVIRRDFKLRSYSLNSVS 360
Query: 791 FHVLHQRLPFYSYKTRTEFYESMDETSKRCLLFYWITRLRVNFKLLETQNIIGKTIEQAR 850
H L ++ Y + E +S ++ ++R + Y + + +L T N++ E +R
Sbjct: 361 IHFLKEQKEDVPYSSIGEL-QSKNKDTRRRIASYCLRDTVLPLRLFNTLNVLINYTELSR 419
Query: 851 LIGIDFYSVLYRGSQYKVESFLIRLCKSEQFILISPSRMQVRNQKALECIPLVMEPSSAF 910
+ G RG K+ + + R E F++ P + K E V+EP F
Sbjct: 420 VTGTPIEYFFTRGMAIKIFTLVYRAASKEDFMI--PDIDPFESNKTFEG-GFVIEPRKGF 476
Query: 911 YKSPLLVLDFQSLYPSIVMAYNYCYSTIIGRVESLNTKNNEIGITRYDIPEDLLTLISDY 970
Y P+ V+DF SLYPSI++++N CY+T++ + + +G T+
Sbjct: 477 YNKPVSVMDFSSLYPSIMISHNLCYTTLLTKEQY-----RILGGTK-------------- 517
Query: 971 ITISPNGIVFVKKELRKSVLAKMLKDILDTRFLMKSTMKELNDEHNLINMLDNRQEALKL 1030
+P G F E +K +L ++L D+L +R +K ++ D L L+ RQ A KL
Sbjct: 518 ---TPTGNYFCSAERKKGLLPRILTDLLTSRKRIKEELEREKDSA-LRACLNGRQLAFKL 573
Query: 1031 LANVTYGYTSASFSGRMPCSDIADSIVQTGRETLERAIEVIET--TKEWG----AKVVYG 1084
AN YG+T AS G++PC +I+ S+ GRE + ++IE +++ G + V+YG
Sbjct: 574 CANSLYGFTGAS-RGKLPCFEISQSVTGFGREMIILTKKLIEENFSRKNGYTHDSVVIYG 632
Query: 1085 DTDSLFVYLPGKSKDEAFVIGRQIAEEITRQNPKPIELKFEKVYHPCFLVTKKRYVGFSY 1144
DTDS+ V + ++ F + ++I+E IT + KP+ L+FEKVY+P L+ KKRY G Y
Sbjct: 633 DTDSVMVDFDEQDIEKVFKMSKEISEFITSKFVKPVSLEFEKVYYPYLLINKKRYAGLLY 692
Query: 1145 ESEYQKEPKFDAKGIETVRRDGTPAQQKIVEKALRIMFETTDLSMVKEYLIGEFDKIITG 1204
S + K D +GIETVRRD +++VE L ++ ++ K+++ + G
Sbjct: 693 -SNPENPSKIDTRGIETVRRDNCRLVKEVVETVLEMILYQKNVEKAKQFVKDAVRDLYLG 751
Query: 1205 RVNIQDFCFAREV-KLGHYKSEKTAPPGAQIAMQMMEEDARTEPQYKQRVPYVVKMGKIG 1263
R ++ ++ + K G K A Q+A ++ + D T P RVPYV+ + G
Sbjct: 752 RTDLSLLVISKSLTKAGDKYESKQA--HVQLAEKLRKRDESTAPVLGDRVPYVIVRKEKG 809
Query: 1264 ETLSSRCLSPEAFLRSKTSRLDYTYYIVKNIIPPLQRFFQLVGVDIMDWYISMKHTLNPL 1323
+ P ++ +D YYI + I PL R F+ + ++ + + HT
Sbjct: 810 AAAHEKSEDP-VYVLENNLPIDTEYYISQQISKPLSRIFEPIMDNVQELFRG-DHT---- 863
Query: 1324 KVDSDDGSHEGRSLTSIVKGKSCLRCRKKVHPKFISPICGECRIDKSNTTLFLEESVRLK 1383
++ + G +G T + +C+ CR + IC C D ++ V K
Sbjct: 864 RIAASTGL-KGPMNTFLKPTDTCVGCRAEGR-----IICINCVKDFHVHLQKMQREVEDK 917
Query: 1384 QSKMHSVMRTCQTCSYKFHKDAMAPLDQIALKCQSKDCPVYFSKFK 1429
+ K++S CQ C H + C ++DCP+++ + K
Sbjct: 918 KEKLNSCWVECQRCQGSIHNQVL---------CVNRDCPIFYMRTK 954
>CE09308 [L] KOG0969 DNA polymerase delta catalytic subunit
Length = 1081
Score = 258 bits (659), Expect = 5e-68
Identities = 210/768 (27%), Positives = 346/768 (44%), Gaps = 87/768 (11%)
Query: 699 DLVRFFDPDILSGYEIHSSSWGYLIDRCHKGHDYDVEDELSRVDYNQSSKKKDRWGYTHA 758
+ VR DPDI++GY I + Y++DR LS + ++K++
Sbjct: 353 EFVREVDPDIITGYNILNFDLPYILDRAKV---------LSLPQVSHLGRQKEKGSVVRD 403
Query: 759 TAFS-------------ITGRQMLNIWRPLRSSLNLLDYTLENIAFHVLHQRLPFYSYKT 805
A S I GR + ++ + + L YTL ++++ L ++ +
Sbjct: 404 AAISSKQMGSRVNKSIDIHGRIIFDVLQVVLRDYKLRSYTLNSVSYQFLSEQKEDVEHNI 463
Query: 806 RTEFYESMDETSKRCLLFYWITRLRVNFKLLETQNIIGKTIEQARLIGIDFYSVLYRGSQ 865
+ DE ++R L Y + + +LL+ I IE AR+ G+ +L +G Q
Sbjct: 464 IPDLQRG-DEQTRRRLAQYCLKDAYLPLRLLDKLMSIINYIEMARVTGVPMNFLLTKGQQ 522
Query: 866 YKVESFLIRLCKSEQFIL--ISPSRMQVRNQKALECIPLVMEPSSAFYKSPLLVLDFQSL 923
K+ S ++R CK F L I + + V++P FY P+ LDF SL
Sbjct: 523 IKILSMMLRRCKQNNFFLPVIEANSGDGEGYEGAT----VIDPIRGFYNEPIATLDFASL 578
Query: 924 YPSIVMAYNYCYSTIIGRVESLNTKNNEIGITRYDIPEDLLTLISDYITISPNGIVFVKK 983
YPSI++A+N CY+T++ + + + DYI +P+G F K
Sbjct: 579 YPSIMIAHNLCYTTLLKSPQGVENE--------------------DYIR-TPSGQYFATK 617
Query: 984 ELRKSVLAKMLKDILDTRFLMKSTMKELNDEHNLINMLDNRQEALKLLANVTYGYTSASF 1043
R+ +L ++L+DIL R K+ MK DE + + + RQ ALK+ AN YG+T A+
Sbjct: 618 SKRRGLLPEILEDILAARKRAKNDMKNEKDEFKRM-VYNGRQLALKISANSVYGFTGATV 676
Query: 1044 SGRMPCSDIADSIVQTGRETLERAIEVIETTKEWGA---------KVVYGDTDSLFVYLP 1094
G++PC +I+ S+ GR+ ++ +E + GA KV+YGDTDS+ V
Sbjct: 677 -GKLPCLEISQSVTAFGRKMIDMTKLEVERIYKKGALDGKCPADAKVIYGDTDSVMVKFG 735
Query: 1095 GKSKDEAFVIGRQIAEEITRQNPKPIELKFEKVYHPCFLVTKKRYVGFSYESEYQKEPKF 1154
++ +A IG A+E+++ PI+L+FEKVY P L+ KKRY G Y ++ K
Sbjct: 736 VETVAQAMEIGLDAAKEVSKIFTPPIKLEFEKVYSPYLLINKKRYAGL-YFTKPDVHDKM 794
Query: 1155 DAKGIETVRRDGTPAQQKIVEKALRIMFETTDLSMVKEYLIGEFDKIITGRVNIQDFCFA 1214
D KG+ETVRRD P K++ L + D ++ ++ +++I +
Sbjct: 795 DCKGLETVRRDNCPLVAKVLGVCLEKLLIERDQQSALDFAKRTISDLLCNKIDISLLIIS 854
Query: 1215 REV-KLGHYKSEKTAPPGAQIAMQMMEEDARTEPQYKQRVPYVVKMGKIGETLSSRCLSP 1273
+E+ K G K A ++A +M + DA + P+ RVPYV R P
Sbjct: 855 KELTKSGDKYQAKQA--HVELAARMKKRDAGSAPRLGDRVPYVFVAAAKNVPAYERAEDP 912
Query: 1274 EAFLRSKTSRLDYTYYIVKNIIPPLQRFFQ-LVGVDIMDWYISMKHTLNPLKVDSDDGSH 1332
F+ LD +Y+ + PL R F+ ++G + +HT +V + S
Sbjct: 913 -TFVLQNNIPLDTKHYLTNQLAKPLARIFEPILGDRAEKILVEGEHT----RVRTVVQSK 967
Query: 1333 EGRSLTSIVKGKSCLRCRKKVHPKFIS--PICGECRIDKSNTTLFLEESVRLKQSKMH-- 1388
G K +CL C K V P+ S +C C + T+F + + + H
Sbjct: 968 VGGLAAFTTKSATCLGC-KSVLPRAESENAVCKHC--EPKLPTIFASRMNTMHELENHFG 1024
Query: 1389 SVMRTCQTCSYKFHKDAMAPLDQIALKCQSKDCPVYFSKFKYMNGLKD 1436
+ CQ C A Q + C ++DCP+Y+ + K N L +
Sbjct: 1025 RLWTECQNC---------AKTMQDKVNCSARDCPIYYMREKVRNELSE 1063
>YDL102w [L] KOG0969 DNA polymerase delta catalytic subunit
Length = 1097
Score = 255 bits (652), Expect = 3e-67
Identities = 230/884 (26%), Positives = 389/884 (43%), Gaps = 96/884 (10%)
Query: 581 KGKFSMVEGKTPELPFGYKFKSNKIEKNNNASNRMTH--------------FTMEIHVNT 626
KGK+SM+E + S ++E + N N + H + +I
Sbjct: 274 KGKYSMIEPNN-------RVSSCQLEVSINYRNLIAHPAEGDWSHTAPLRIMSFDIECAG 326
Query: 627 REDKFPDPKYDAVRMIFWKVQDGTFPFDLDITQEGVLIFLDDVSTENSWKTADPSVHITA 686
R FP+P+YD V I V F+ +V T N+ S+ I +
Sbjct: 327 RIGVFPEPEYDPVIQIANVVS----------IAGAKKPFIRNVFTLNTCSPITGSM-IFS 375
Query: 687 YYDELEMIYALEDLVRFFDPDILSGYEIHSSSWGYLIDRCH--KGHDYDVEDELSRV--D 742
+ E EM+ + + DPD++ GY + YL++R K +D+ L V +
Sbjct: 376 HATEEEMLSNWRNFIIKVDPDVIIGYNTTNFDIPYLLNRAKALKVNDFPYFGRLKTVKQE 435
Query: 743 YNQSSKKKDRWGYTHATAFSITGRQMLNIWRPLRSSLNLLDYTLENIAFHVLHQRLPFYS 802
+S +G +I GR L++ + ++ L YTL ++ H L ++
Sbjct: 436 IKESVFSSKAYGTRETKNVNIDGRLQLDLLQFIQREYKLRSYTLNAVSAHFLGEQKEDVH 495
Query: 803 YKTRTEFYESMDETSKRCLLFYWITRLRVNFKLLETQNIIGKTIEQARLIGIDFYSVLYR 862
Y ++ ET +R L Y + + +L+E + E AR+ G+ F +L R
Sbjct: 496 YSIISDLQNGDSETRRR-LAVYCLKDAYLPLRLMEKLMALVNYTEMARVTGVPFSYLLAR 554
Query: 863 GSQYKVESFLIRLCKSEQFILISPSRMQVRNQKALECIPLVMEPSSAFYKSPLLVLDFQS 922
G Q KV S L R C ++ P+ + E V+EP +Y P+ LDF S
Sbjct: 555 GQQIKVVSQLFRKCLEIDTVI--PNMQSQASDDQYEGAT-VIEPIRGYYDVPIATLDFNS 611
Query: 923 LYPSIVMAYNYCYSTIIGR--VESLNTKNNEIGITRYDIPEDLLTLISDYITISPNGIVF 980
LYPSI+MA+N CY+T+ + VE LN K +E DY+ I+PNG F
Sbjct: 612 LYPSIMMAHNLCYTTLCNKATVERLNLKIDE-----------------DYV-ITPNGDYF 653
Query: 981 VKKELRKSVLAKMLKDILDTRFLMKSTMKELNDEHNLI--NMLDNRQEALKLLANVTYGY 1038
V + R+ +L +L +++ R K K+L DE + ++L+ RQ ALK+ AN YG+
Sbjct: 654 VTTKRRRGILPIILDELISAR---KRAKKDLRDEKDPFKRDVLNGRQLALKISANSVYGF 710
Query: 1039 TSASFSGRMPCSDIADSIVQTGRETL---ERAIE---VIETTKEWGAKVVYGDTDSLFVY 1092
T A+ G++PC I+ S+ GR + + A++ I+ + A VVYGDTDS+ V
Sbjct: 711 TGATV-GKLPCLAISSSVTAYGRTMILKTKTAVQEKYCIKNGYKHDAVVVYGDTDSVMVK 769
Query: 1093 LPGKSKDEAFVIGRQIAEEITRQNPKPIELKFEKVYHPCFLVTKKRYVGFSYESEYQKEP 1152
EA +G + A+ ++ PI L+FEK Y P L+ KKRY G + + K
Sbjct: 770 FGTTDLKEAMDLGTEAAKYVSTLFKHPINLEFEKAYFPYLLINKKRYAGLFWTNP-DKFD 828
Query: 1153 KFDAKGIETVRRDGTPAQQKIVEKALRIMFETTDLSMVKEYLIGEFDKIITGRVNIQDFC 1212
K D KG+ +VRRD ++ K L+ + ++ ++ + I+ RV+I
Sbjct: 829 KLDQKGLASVRRDSCSLVSIVMNKVLKKILIERNVDGALAFVRETINDILHNRVDISKLI 888
Query: 1213 FAREVKLGHYKSEKTAPPGAQIAMQMMEEDARTEPQYKQRVPYVVKMGKIGETLSSRCLS 1272
++ + + T P + + M+ P RV YV+ G + L +R
Sbjct: 889 ISKTLAPNY-----TNPQPHAVLAERMKRREGVGPNVGDRVDYVIIGG--NDKLYNRAED 941
Query: 1273 PEAFLRSKTSRLDYTYYIVKNIIPPLQRFFQLVGVDIMDWYISMKHTLNPLKVDSDDGSH 1332
P F+ ++D YY+ + P+ +V I D + + +K+++ GS
Sbjct: 942 P-LFVLENNIQVDSRYYLTNQLQNPI---ISIVAPIIGDKQANGMFVVKSIKINT--GSQ 995
Query: 1333 EGRSLTSIVKGKSCLRCRKKVHPKFISPICGECRIDKSNTTLFLEESVRLKQSKMHSVMR 1392
+G ++ I K ++C C+ + K P+C C + VR + K +
Sbjct: 996 KGGLMSFIKKVEACKSCKGPLR-KGEGPLCSNCLARSGELYIKALYDVRDLEEKYSRLWT 1054
Query: 1393 TCQTCSYKFHKDAMAPLDQIALKCQSKDCPVYFSKFKYMNGLKD 1436
CQ C+ H + + C +K+C +++ + K L++
Sbjct: 1055 QCQRCAGNLHSEVL---------CSNKNCDIFYMRVKVKKELQE 1089
>Hs8393995 [L] KOG0970 DNA polymerase alpha catalytic subunit
Length = 1462
Score = 137 bits (344), Expect = 2e-31
Identities = 167/766 (21%), Positives = 310/766 (39%), Gaps = 83/766 (10%)
Query: 574 ANAMKPFKGKFSMVEGKTPELPFGYKFKSNKIEKNNNASNRMTHFTMEIHVNTREDKF-P 632
A A+KP ++++ +P F ++ N N + +H + DK P
Sbjct: 518 AMALKP--DLVNVIKDVSPPPLVVMAFSMKTMQNAKNHQNEIIAMAALVHHSFALDKAAP 575
Query: 633 DPKYDAVRMIFWKVQDGTFPFDLDITQEGVLIFLDDVSTENSWKTADPSVHITAYYDELE 692
P + + + K +D FP+ F + + +N V + E
Sbjct: 576 KPPFQSHFCVVSKPKDCIFPY----------AFKEVIEKKN--------VKVEVAATERT 617
Query: 693 MIYALEDLVRFFDPDILSGYEIHSSSWGYLIDR---CHKGHDYDVEDELSRVDYNQSSKK 749
++ V DPDI+ G+ I+ L+ R C H ++ R+ + K
Sbjct: 618 LLGFFLAKVHKIDPDIIVGHNIYGFELEVLLQRINVCKAPH----WSKIGRLKRSNMPKL 673
Query: 750 KDRWGYTHATAFSITGRQMLNIWRPLRSSLNLLDYTLENIAFHVLHQR---LPFYS---- 802
R G+ A GR + ++ + + Y L + +L +P +
Sbjct: 674 GGRSGFGERNA--TCGRMICDVEISAKELIRCKSYHLSELVQQILKTERVVIPMENIQNM 731
Query: 803 YKTRTEFYESMDETSKRCLLFYWIT-RLRVNFKLLETQNIIGKTIEQARLIGIDFYSVLY 861
Y ++ ++ T K I L V L+ NI G + + + G +
Sbjct: 732 YSESSQLLYLLEHTWKDAKFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFL 791
Query: 862 RGSQYKVESFLI-----------RLCKSEQFILISPSRMQVRNQKALECIPLVMEPSSAF 910
+ ++++ +L ++ I ++ + +K LV++P F
Sbjct: 792 LLHAFYENNYIVPDKQIFRKPQQKLGDEDEEIDGDTNKYKKGRKKGAYAGGLVLDPKVGF 851
Query: 911 YKSPLLVLDFQSLYPSIVMAYNYCYSTIIGRVESLNTKNNEIGITRYDIPEDLLTLISDY 970
Y +L+LDF SLYPSI+ +N C++T + RV S K E G + IPE
Sbjct: 852 YDKFILLLDFNSLYPSIIQEFNICFTT-VQRVASEAQKVTEDG-EQEQIPE--------- 900
Query: 971 ITISPNGIVFVKKELRKSVLAKMLKDILDTRFLMKSTMKELNDEHNLINMLDNRQEALKL 1030
L +L + ++ +++ R +K MK+ + +LI D RQ+ALKL
Sbjct: 901 ---------LPDPSLEMGILPREIRKLVERRKQVKQLMKQQDLNPDLILQYDIRQKALKL 951
Query: 1031 LANVTYGYTSASFSGRMPCSDIADSIVQTGRETLERAIEVIETTKEWGAKVVYGDTDSLF 1090
AN YG S+S R +A + GRE L E+++ + +V+YGDTDS+
Sbjct: 952 TANSMYGCLGFSYS-RFYAKPLAALVTYKGREILMHTKEMVQ---KMNLEVIYGDTDSIM 1007
Query: 1091 VYLPGKSKDEAFVIGRQIAEEITRQNPKPIELKFEKVYHPCFLVTKKRYVGFSYE--SEY 1148
+ + +E F +G ++ E+ + K +E+ + V+ L+ KK+Y E S+
Sbjct: 1008 INTNSTNLEEVFKLGNKVKSEVNKLY-KLLEIDIDGVFKSLLLLKKKKYAALVVEPTSDG 1066
Query: 1149 QKEPKFDAKGIETVRRDGTPAQQK----IVEKALRIMFETTDLSMVKEYLIGEFDKIITG 1204
K + KG++ VRRD + ++ + L T + +++ LI + ++ G
Sbjct: 1067 NYVTKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNG 1126
Query: 1205 RVNIQDFCFAREV-KLGHYKSEKTAPPGAQIAMQMMEEDARTEPQYKQRVPYVVKMGKIG 1263
V + F + + K +K + P +A+ + + R + + V YV+
Sbjct: 1127 SVPVSQFEINKALTKDPQDYPDKKSLPHVHVALWINSQGGR-KVKAGDTVSYVICQDGSN 1185
Query: 1264 ETLSSRCLSPEAFLRSKTSRLDYTYYIVKNIIPPLQRFFQLV-GVD 1308
T S R +PE + +D YY+ + I P + R + + G+D
Sbjct: 1186 LTASQRAYAPEQLQKQDNLTIDTQYYLAQQIHPVVARICEPIDGID 1231
>SPAC3H5.06c [L] KOG0970 DNA polymerase alpha catalytic subunit
Length = 1405
Score = 129 bits (325), Expect = 3e-29
Identities = 131/528 (24%), Positives = 229/528 (42%), Gaps = 95/528 (17%)
Query: 902 LVMEPSSAFYKSPLLVLDFQSLYPSIVMAYNYCYSTIIGRVESLNTKNNEIGITRYDIPE 961
LV EP Y++ +LV+DF SLYPSI+ YN C++T + R S + +++
Sbjct: 829 LVFEPQKGLYETCILVMDFNSLYPSIIQEYNICFTT-VDRSPSNSDSDDQ---------- 877
Query: 962 DLLTLISDYITISPNGIVFVKKELRKSVLAKMLKDILDTRFLMKSTMKELNDEHNLINML 1021
I D + S N + + +++ ++++ R +K +K+ +
Sbjct: 878 -----IPDTPSASAN----------QGIFPRLIANLVERRRQIKGLLKDNSATPTQRLQW 922
Query: 1022 DNRQEALKLLANVTY---GYTSASFSGRMPCSDIADSIVQTGRETLERAIEVIETTKEWG 1078
D +Q+ALKL AN Y GYT + F R +A I GRE L E+ + + G
Sbjct: 923 DIQQQALKLTANSMYGCLGYTKSRFYAR----PLAVLITYKGREALMNTKELAD---QMG 975
Query: 1079 AKVVYGDTDSLFVYLPGKSKDEAFVIGRQIAEEITRQNPKPIELKFEKVYHPCFLVTKKR 1138
+V+YGDTDS+ + K+ A IG + E++ + K +E+ + VY L KK+
Sbjct: 976 LQVIYGDTDSVMLNTNVTDKNHALRIGNEFKEKVNERYSK-LEIDIDNVYQRMLLHAKKK 1034
Query: 1139 YVGFSYESEYQKEPKFDAKGIETVRRD----GTPAQQKIVEKALRIMFETTDLSMVKEYL 1194
Y +S Q +P D KG++ RR+ A + +++ L T + + YL
Sbjct: 1035 YAALQLDS--QGKPNLDVKGLDMKRREFCTLAKEASKFCLDQILSGELTETVIENIHSYL 1092
Query: 1195 IGEFDKIITGRVNIQDFCFAREVKLG----HYKSEKTAPPGAQIAMQMMEEDARTE-PQY 1249
+ +K+ G+ F +LG Y + KT P Q+A +++ AR E +
Sbjct: 1093 MDFSEKMRNGKFPANKFIIFN--RLGKNPEDYPNGKTM-PFVQVA---LKKKARGENVRV 1146
Query: 1250 KQRVPYVVKMGKIGETLSSRCLSPEAFLR-SKTSRLDYTYYIVKNIIPPLQRFF------ 1302
+P+++ + R SP+ + + T +DY YY+ I+PP++R
Sbjct: 1147 GDVIPFIIAGSDADGHPADRAYSPQEIMNTNSTLVIDYNYYLSHQILPPIERVIAPIEGT 1206
Query: 1303 ------QLVGVDIMDWYISMKHTLNPLKVDSDDGSHEGRSLTSIVKGKSCL---RCRKKV 1353
+ +G+D +Y SHE ++ + +S L +C V
Sbjct: 1207 NRARLAECLGLDARKYY-----------------SHETSESSAFQRYESTLTDDQCFINV 1249
Query: 1354 HPKFISPICGECRIDKSNTTLFLEESVRLKQSKMHSVMRTCQTCSYKF 1401
P + C C N T F SV+ + +++ C C Y++
Sbjct: 1250 SPLLLK--CPSC-----NATSFSLRSVKSLKETLYANTVECD-CGYEY 1289
>ECU05g0990 [L] KOG0970 DNA polymerase alpha catalytic subunit
Length = 956
Score = 127 bits (319), Expect = 1e-28
Identities = 142/555 (25%), Positives = 242/555 (43%), Gaps = 89/555 (16%)
Query: 902 LVMEPSSAFYKSPLLVLDFQSLYPSIVMAYNYCYSTIIGRVESLNTKNNEIGITRYDIPE 961
LV+ P + FY+ +L+LDF SLYPSI+ +N C+ST IG + + N E
Sbjct: 407 LVLPPQTGFYEDLVLLLDFNSLYPSIIQEFNVCFST-IGMFDRSISGNMS--------SE 457
Query: 962 DLLTLISDYITISPNGIVFVKKELRKSVLAKMLKDILDTRFLMKSTMKELNDEHNLINML 1021
L+ L D K + L ++L+ + R +K +K+ L
Sbjct: 458 QLVRLTED------------AKNSERGFLPRILEGFVRRRKAVKDLLKQGGTPEE-TKAL 504
Query: 1022 DNRQEALKLLANVTYGYTSASFSGRMPCS-DIADSIVQTGRETLERAIEVIETTKEWGAK 1080
D RQ+ALKL AN YG F G C+ +A I GR+ L A + E E G +
Sbjct: 505 DIRQKALKLTANSIYG--CLGFVGSRFCNYTMAAYITSKGRDLLLEAKRIAE--GECGVR 560
Query: 1081 VVYGDTDSLFVY--LPGKSKD--EAFVIGRQIAEEITRQNPKPIELKFEKVYHPCFLVTK 1136
++YGDTDS+ V+ L GK + +A + R++ + I + K IE++ +KV+ L K
Sbjct: 561 IIYGDTDSVMVHTGLAGKKSNYTKALELSRRLQDAINSRY-KKIEIEVDKVFKKLLLYKK 619
Query: 1137 KRYVGFSYESEYQKEPKFDAKGIETVRRDGTPAQQKIVEKALRIMF-ETTDLSMVKEYLI 1195
KRY G + + + + KG++ VR+D +KI L ++ + D + +
Sbjct: 620 KRYAGLYMTDD--GKGRIEYKGLDLVRKDFCEVSRKICRIVLELLLADCEDPETYRRFYE 677
Query: 1196 GEFDKIIT-GRVNIQDFCF--------------AREVKLGHYKSEK-------TAPPGAQ 1233
GE ++ G + I++ + ARE + + S+ A P
Sbjct: 678 GEPKMVLNDGSIKIREAVYDELRKVSSDLEGIPAREFVIHNTLSKAPESYDACAALPHVS 737
Query: 1234 IAMQMMEEDARTEPQYKQRVPYVVKMGKIGETLSSRCLSPEAFLRSKTSRLDYTYYIVKN 1293
+A+++ E + E V YV+ G G+ + R P+ + +DY YYI
Sbjct: 738 LALRLKERGMKFE--QGDVVCYVIGKGDPGQAIHKRAYHPD-----EDFAIDYGYYISSQ 790
Query: 1294 IIPPLQRFFQLVGVDIMDWYISMKHTLNPLKVDSDDGSHEGRSLTSI-----VKGKSCLR 1348
I+PPL R +VG+ + ++ + V+S S ++++ + V ++ LR
Sbjct: 791 ILPPLLR---VVGI-VKGFHAGKIGKI--FGVESVPKSEVQKAISFLSPCCEVSQEATLR 844
Query: 1349 CRKKVHPKFISPICGECRIDKSNTTLFLEESVRLKQSKMHSVMRTCQTC---SYKFHKDA 1405
CR+ P IS C++ E +R + ++S C C SY K
Sbjct: 845 CRECSRP--ISRAFYACKV---------TEMLRKEVESLYSAESRCTECGVSSYTHMKTC 893
Query: 1406 MAPLDQIALKCQSKD 1420
+++ ++D
Sbjct: 894 FVCNSELSFTAHNQD 908
>CE26106 [L] KOG0970 DNA polymerase alpha catalytic subunit
Length = 1443
Score = 121 bits (304), Expect = 7e-27
Identities = 136/625 (21%), Positives = 266/625 (41%), Gaps = 76/625 (12%)
Query: 705 DPDILSGYEIHSSSWGYLIDRCHKGHDYDVEDELSRVDYNQSSKKKDRWGYTHATAFSIT 764
+PD++ G+++ S++ L+ R K SR+ + S + G++ + + +T
Sbjct: 616 EPDMIVGHDL-SATIALLVSRLEKLK----LPNWSRISRLKRSINIGKIGHSKSGQWELT 670
Query: 765 -GRQMLNIWRPLRSSLNLLDYTLENIAFHVLH-QRLPFYSYKTRTEFYESMDETSKRCLL 822
GR ML+ + + L ++ +L +R Y+ + + +S D S L+
Sbjct: 671 AGRMMLDSKLAAMELVKSRSFDLTELSQQILGAERREIYANEIPQLYVDSKDLIS---LI 727
Query: 823 FYWITRLRVNFKLLETQNIIGKTIEQARLIGIDFYSVLYRGSQYKVESFLIRLCKSEQFI 882
+ L ++ +++ N + I+ ++++G + G + E L+ E+
Sbjct: 728 NWSWNDLLLSLRIVVRLNALPLYIQISQIVGGIASRTMMGGRAERNEYLLLHAF--EKAD 785
Query: 883 LISPSRM----------------QVRNQKALECIPLVMEPSSAFYKSPLLVLDFQSLYPS 926
LI+P + + ++ KA LV+EP Y++ +L+LDF SLYPS
Sbjct: 786 LIAPDKYNSSESKKKKEESQEGDEKKSGKAQYSGGLVLEPKKGLYETLILLLDFNSLYPS 845
Query: 927 IVMAYNYCYSTIIGRVESLNTKNNEIGITRYDIPEDLLTLISDYITISPNGIVFVKKELR 986
I+ YN CY+T+ E + ++ + + E +L +E+R
Sbjct: 846 IIQEYNICYTTL----EYSKDSDEQLSVPQSTDIEGVL-----------------PREIR 884
Query: 987 KSVLAKMLKDILDTRFLMKSTMKELNDEHNLINMLDNRQEALKLLANVTYGYTSASFSGR 1046
K V + D + LMKS E + +D RQ ALKL AN YG +S R
Sbjct: 885 KLVECRR-----DVKSLMKSERNEAKKK-----QMDIRQMALKLTANSMYGCLGFQYS-R 933
Query: 1047 MPCSDIADSIVQTGRETLERAIEVIETTKEWGAKVVYGDTDSLFVYLPGKSKDEAFVIGR 1106
+A + GRE L + +++E + G VVYGDTDS+ + A +G
Sbjct: 934 FYAKPLAALVTAKGREILMHSKDLVE---KMGYSVVYGDTDSIMINTNSVDLVAAKKLGN 990
Query: 1107 QIAEEITRQNPKPIELKFEKVYHPCFLVTKKRYVGFSYESEYQKEPKFDAKGIETVRRDG 1166
+I + + + + + +EL + V+ L+ KK+Y + + + E K + KG++ VRRD
Sbjct: 991 EIKKAVNKCH-RLLELDLDGVFKRMLLLKKKKYAALTINPDTKVEAK-ELKGLDIVRRDW 1048
Query: 1167 TPAQQKIVEKALRIMFETTDLSMVKEYLIGEFD--------KIITGRVNIQDFCFAREVK 1218
+ Q E ++ + D S+ ++ ++ D K+ +G V ++ F ++++
Sbjct: 1049 S---QLAKETGTAVVDKILDASLTRDEMVSSIDDLLREIRAKLDSGTVPLEMFQISKQLT 1105
Query: 1219 LGHYKSEKTAPPGAQIAMQMMEEDARTEPQYKQRVPYVVKMGKIGETLSSRCLSPEAFLR 1278
+ Q + + + ++ V YV+ + R
Sbjct: 1106 RNPEQYADVKAQCHAAVAQRLNKSGKFNLRHNDIVEYVICEDGTDNPATQRAYHRTEMAE 1165
Query: 1279 SKTSRLDYTYYIVKNIIPPLQRFFQ 1303
+ ++D YY+ + I P + R +
Sbjct: 1166 NSALKIDLLYYLAQQIHPVVSRLVE 1190
>At5g67100 [L] KOG0970 DNA polymerase alpha catalytic subunit
Length = 1492
Score = 115 bits (289), Expect = 4e-25
Identities = 154/653 (23%), Positives = 277/653 (41%), Gaps = 100/653 (15%)
Query: 705 DPDILSGYEIHSSSWGYLIDRCHKGH-DYDVEDELSRVDYNQSSKKKDRWGY----THAT 759
D DIL G+ I L+ R + ++ R+ + K K Y T
Sbjct: 664 DSDILVGHNISGFDLDVLLQRAQACKVQSSMWSKIGRLKRSFMPKLKGNSNYGSGATPGL 723
Query: 760 AFSITGRQMLNIWRPLRSSLNLLDYTLENIAFHVLHQR--------LP--FYSYKTRTEF 809
I GR + + R L + Y+L +++ L++ +P F S KT E
Sbjct: 724 MSCIAGRLLCDTDLCSRDLLKEVSYSLTDLSKTQLNRDRKEIAPNDIPKMFQSSKTLVEL 783
Query: 810 YESMDETSKRCL-LFYWITRLRVNFKLLETQ-NIIGKTIEQARLIGIDFYSV-LYRGSQY 866
E + + + L + ++ L + +L N+ GKT++ AR I++Y + + ++
Sbjct: 784 IECGETDAWLSMELMFHLSVLPLTLQLTNISGNLWGKTLQGARAQRIEYYLLHTFHSKKF 843
Query: 867 ----KVESFLIRLCKSEQFILISPSRMQVRNQKA---LECIP---------------LVM 904
K+ + + S++ + +P V A LE P LV+
Sbjct: 844 ILPDKISQRMKEIKSSKRRMDYAPEDRNVDELDADLTLENDPSKGSKTKKGPAYAGGLVL 903
Query: 905 EPSSAFYKSPLLVLDFQSLYPSIVMAYNYCYSTIIGRVESLNTKNNEIGITRY---DIPE 961
EP Y +L+LDF SLYPSI+ YN C++TI +E G+ R P
Sbjct: 904 EPKRGLYDKYVLLLDFNSLYPSIIQEYNICFTTI---------PRSEDGVPRLPSSQTPG 954
Query: 962 DLLTLISDYITISPNGIVFVKKELRKSVLAKMLKDILDTRFLMKSTMKELNDEHNLINML 1021
L L+ ++I RKSV KM K+ + +K L
Sbjct: 955 ILPKLMEHLVSI------------RKSVKLKMKKE---------TGLKYWE--------L 985
Query: 1022 DNRQEALKLLANVTYGYTSASFSGRMPCSDIADSIVQTGRETLERAIEVIETTKEWGAKV 1081
D RQ+ALKL AN YG S + R +A+ I GR+ L+R +++++ +V
Sbjct: 986 DIRQQALKLTANSMYGCLGFS-NSRFYAKPLAELITLQGRDILQRTVDLVQ--NHLNLEV 1042
Query: 1082 VYGDTDSLFVYLPGKSKDEAFVIGRQIAEEITRQNPKPIELKFEKVYHPCFLVTKKRYVG 1141
+YGDTDS+ ++ +E I ++ +E+ ++ + +++ + +Y L+ KK+Y
Sbjct: 1043 IYGDTDSIMIHSGLDDIEEVKAIKSKVIQEVNKKY-RCLKIDCDGIYKRMLLLRKKKYAA 1101
Query: 1142 FSYESEYQKE-PKFDAKGIETVRRDGTPAQQKIVEKALRIMFETTDLSMVKEYLIGEFDK 1200
+ + K + KG++ VRRD + ++I + L + V E + E K
Sbjct: 1102 VKLQFKDGKPCEDIERKGVDMVRRDWSLLSKEIGDLCLSKILYGGSCEDVVEAIHNELMK 1161
Query: 1201 I----ITGRVNIQDFCFAREV-KLGHYKSEKTAPPGAQIAMQMMEEDARTEPQYKQRVPY 1255
I G+V ++ + + + K + + P Q+A++M + + K VPY
Sbjct: 1162 IKEEMRNGQVALEKYVITKTLTKPPAAYPDSKSQPHVQVALRMRQRGYKEGFNAKDTVPY 1221
Query: 1256 VV--KMGKIGET----LSSRCLSPEAFLRSKTSR--LDYTYYIVKNIIPPLQR 1300
++ + G ++ R P+ ++S+ SR +D YY+ + I P + R
Sbjct: 1222 IICYEQGNASSASSAGIAERARHPDE-VKSEGSRWLVDIDYYLAQQIHPVVSR 1273
>YNL102w [L] KOG0970 DNA polymerase alpha catalytic subunit
Length = 1468
Score = 107 bits (268), Expect = 1e-22
Identities = 105/434 (24%), Positives = 182/434 (41%), Gaps = 59/434 (13%)
Query: 891 VRNQKALECIPLVMEPSSAFYKSPLLVLDFQSLYPSIVMAYNYCYSTIIGRVESLNTKNN 950
V ++KA LV EP +K+ +LV+DF SLYPSI+ +N C++T+ E ++
Sbjct: 836 VNSKKAKYQGGLVFEPEKGLHKNYVLVMDFNSLYPSIIQEFNICFTTVDRNKEDID---- 891
Query: 951 EIGITRYDIPEDLLTLISDYITISPNGIVFVKKELRKSVLAKMLKDILDTRFLMKSTMKE 1010
++P ++ P+ E+ + VL ++L +++D R +K MK
Sbjct: 892 -------ELP-----------SVPPS-------EVDQGVLPRLLANLVDRRREVKKVMKT 926
Query: 1011 LNDEHNLINMLDNRQEALKLLANVTYGYTSASFSGRMPCSDIADSIVQTGRETLERAIEV 1070
D H + D RQ+ALKL AN YG + R +A + GRE L ++
Sbjct: 927 ETDPHKRVQC-DIRQQALKLTANSMYG-CLGYVNSRFYAKPLAMLVTNKGREILMNTRQL 984
Query: 1071 IETTKEWGAKVVYGDTDSLFVYLPGKSKDEAFVIGRQIAEEITRQNPKPIELKFEKVYHP 1130
E+ VVYGDTDS+ + + +A IG + + + + +E+ + V+
Sbjct: 985 AES---MNLLVVYGDTDSVMIDTGCDNYADAIKIGLGF-KRLVNERYRLLEIDIDNVFKK 1040
Query: 1131 CFLVTKKRYVGF--SYESEYQKEPKFDAKGIETVRRDGTPAQQKIVEKALRIMFETTD-- 1186
L KK+Y + + + KG++ RR+ P + + L + D
Sbjct: 1041 LLLHAKKKYAALTVNLDKNGNGTTVLEVKGLDMKRREFCPLSRDVSIHVLNTILSDKDPE 1100
Query: 1187 --LSMVKEYLIGEFDKIITGRVNIQDFCFAREVKLGHYKSEKTAP-----PGAQIAMQMM 1239
L V +YL K+ T + I + ++ + K K P P Q+A++ M
Sbjct: 1101 EALQEVYDYLEDIRIKVETNNIRIDKY----KINMKLSKDPKAYPGGKNMPAVQVALR-M 1155
Query: 1240 EEDARTEPQYKQRVPYVVKMGKIGETLSSRCLS--------PEAFLRSKTSRLDYTYYIV 1291
+ R + K +I + LS E ++S D YY+
Sbjct: 1156 RKAGRVVKAGSVITFVITKQDEIDNAADTPALSVAERAHALNEVMIKSNNLIPDPQYYLE 1215
Query: 1292 KNIIPPLQRFFQLV 1305
K I P++R + +
Sbjct: 1216 KQIFAPVERLLERI 1229
>7300763 [L] KOG0970 DNA polymerase alpha catalytic subunit
Length = 1472
Score = 99.8 bits (247), Expect = 3e-20
Identities = 101/419 (24%), Positives = 177/419 (42%), Gaps = 57/419 (13%)
Query: 894 QKALECIPLVMEPSSAFYKSPLLVLDFQSLYPSIVMAYNYCYSTIIGRVESLNTKNNEIG 953
+KA LV+EP Y+ +L++DF SLYPSI+ YN C++T+
Sbjct: 855 KKAAYAGGLVLEPMRGLYEKYVLLMDFNSLYPSIIQEYNICFTTV--------------- 899
Query: 954 ITRYDIPEDLLTLISDYITISPNGIVFVKKELRKSVLAKMLKDILDTRFLMKSTMKELND 1013
+ + D L + D + +L LK ++++R +K M +
Sbjct: 900 --QQPVDADELPTLPD-------------SKTEPGILPLQLKRLVESRKEVKKLMAAPDL 944
Query: 1014 EHNLINMLDNRQEALKLLANVTYGYTSASFSGRMPCSDIADSIVQTGRETLERAIEVIET 1073
L RQ ALKL AN YG + S R +A + GRE L ++++
Sbjct: 945 SPELQMQYHIRQMALKLTANSMYGCLGFAHS-RFFAQHLAALVTHKGREILTNTQQLVQ- 1002
Query: 1074 TKEWGAKVVYGDTDSLFVYLPGKSKDEAFVIGRQIAEEITRQNPKPIELKFEKVYHPCFL 1133
+ VVYGDTDSL + D+ + IG I + + + K +EL + V+ L
Sbjct: 1003 --KMNYDVVYGDTDSLMINTNITDYDQVYKIGHNIKQSVNKLY-KQLELDIDGVFGCLLL 1059
Query: 1134 VTKKRY--VGFSYESEYQKEPKFDAKGIETVRRDGTPAQQKIVEKALRIMFETTDLSMVK 1191
+ KK+Y + S +S+ + + KG++ VRRD + + + L + L
Sbjct: 1060 LKKKKYAAIKLSKDSKGNLRREQEHKGLDIVRRDWSQLAVMVGKAVLDEVLSEKPLEEKL 1119
Query: 1192 EYLIGEFDKIIT----GRVNIQDFCFAREV-KLGHYKSEKTAPPGAQIAMQMMEEDARTE 1246
+ + + +KI T G V + F +++ + + + P Q+A++M E R
Sbjct: 1120 DAVHAQLEKIKTQIAEGVVPLPLFVITKQLTRTPQEYANSASLPHVQVALRMNRERNRRY 1179
Query: 1247 PQYKQRVPYVVKMGKIGETLSSRCLSPEAFLRSKTSRLDYTYYIVKNIIPPLQRFFQLV 1305
+ R ++ ++ K E K +LD YY+ I P + R +++
Sbjct: 1180 KKGDMRAYHLDEL-KTSE--------------DKKLQLDTNYYLGHQIHPVVTRMVEVL 1223
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.137 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,883,900
Number of Sequences: 60738
Number of extensions: 3783167
Number of successful extensions: 9598
Number of sequences better than 1.0e-05: 20
Number of HSP's better than 0.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 9425
Number of HSP's gapped (non-prelim): 49
length of query: 1451
length of database: 30,389,216
effective HSP length: 119
effective length of query: 1332
effective length of database: 23,161,394
effective search space: 30850976808
effective search space used: 30850976808
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)