ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2469 check: MH L KOG1977 Replication, recombination and repair DNA mismatch repair protein - MLH3 family
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII2469 867036 864925 -704
(704 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL164c [L] KOG1977 DNA mismatch repair protein - MLH3 family 400 e-111
Hs7657337 [L] KOG1977 DNA mismatch repair protein - MLH3 family 117 8e-26
Hs4557757 [L] KOG1979 DNA mismatch repair protein - MLH1 family 98 4e-20
ECU05g0300 [L] KOG1979 DNA mismatch repair protein - MLH1 family 98 5e-20
CE19915 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2... 96 2e-19
At4g09140 [L] KOG1979 DNA mismatch repair protein - MLH1 family 94 5e-19
YNL082w [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2... 91 8e-18
SPAC19G12.02c [L] KOG1978 DNA mismatch repair protein - MLH2/PMS... 90 1e-17
YMR167w [L] KOG1979 DNA mismatch repair protein - MLH1 family 89 2e-17
CE18978 [L] KOG1979 DNA mismatch repair protein - MLH1 family 89 2e-17
7304079 [L] KOG1979 DNA mismatch repair protein - MLH1 family 84 1e-15
SPBC1703.04 [L] KOG1979 DNA mismatch repair protein - MLH1 family 83 2e-15
Hs4505911 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pm... 81 5e-15
At4g35520 [L] KOG1977 DNA mismatch repair protein - MLH3 family 80 1e-14
At4g02460 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pm... 72 2e-12
7303075 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2... 72 2e-12
ECU11g1260 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/P... 70 1e-11
Hs4505913 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pm... 67 9e-11
YLR035c [R] KOG0017 FOG: Transposon-encoded proteins with TYA re... 57 1e-07
Hs22046611 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/P... 52 4e-06
>YPL164c [L] KOG1977 DNA mismatch repair protein - MLH3 family
Length = 715
Score = 400 bits (1027), Expect = e-111
Identities = 247/724 (34%), Positives = 386/724 (53%), Gaps = 52/724 (7%)
Query: 3 IKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERFIIEVQDNGFGI 62
I++LD VS RLKS VS + VRE+VQNSVDA AT I V I+ V D+G G+
Sbjct: 5 IRKLDSDVSERLKSQACTVSLASAVREIVQNSVDAHATTIDVMIDLPNLSFAVYDDGIGL 64
Query: 63 TPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLIISKSKDYSGIWAR 122
T SDLN+L N TSK+ + L + +YG+RG+AL+ + S + + SK KDY+ W R
Sbjct: 65 TRSDLNILATQNYTSKIRKMNDLVTMKTYGYRGDALYSISNVSNLFVCSKKKDYNSAWMR 124
Query: 123 ELPAPAFISDEGKF----PLMK-----GALSGTVIKISDVFYNYPVRRKMMEKQSISDLV 173
+ P+ + + E P K SGTV+ + D+ YN PVRR++++++
Sbjct: 125 KFPSKSVMLSENTILPIDPFWKICPWSRTKSGTVVIVEDMLYNLPVRRRILKEEPPFKTF 184
Query: 174 SAIRTEILTVLIKFPTLDVSVFINQQLRISSIAV----STLEPYPK--QLDTCFHNIFGE 227
+ I+ ++L +L+ P + ++V +LRI++ + + E K Q+ N+FG
Sbjct: 185 NTIKADMLQILVMHPMISLNVQYTDKLRINTEVLFRSKNITEGLTKHQQMSQVLRNVFGA 244
Query: 228 ILPRKQLKFVSASFKSHTVKGIVSINPIQSKDYQYIFINGRKYSDSRFFSAVNKLFQSTK 287
I+P LK VS F + ++GI+S P+ KD Q+I+INGR+Y+DS F V+ LFQ+
Sbjct: 245 IIPPDMLKKVSLKFNEYQIEGIISKMPVGLKDLQFIYINGRRYADSAFQGYVDSLFQAQD 304
Query: 288 YVEKNWDSYSVKSVGSPYSAYPLFIIGCEVPLEISDLIQDPGKTIFQSGTLKTLCPLILN 347
+ EK KSVG PY ++P+FI+ P I DL+QDP K I + ++T+ PLI+
Sbjct: 305 FGEKGMSLLKTKSVGKPYRSHPVFILDVRCPQTIDDLLQDPAKKIVKPSHIRTIEPLIVK 364
Query: 348 VMSSFLKHLGYEPGVDVSTFDNSSYFETAHYFTNTKRV---ELAVKPTNKHANGNRVHKP 404
+ SFL GY ++ + S FE + T + + + N+ N
Sbjct: 365 TIRSFLTFQGY-----LTPDKSDSSFEIVNCSQKTATLPDSRIQISKRNQVLNSKMKIAR 419
Query: 405 QNNKVLEILKSPPRTRGIFSRLLENTTGGRQCRDHHYDSEFD--IQKLNLAGTESSYLKN 462
N+ + P G R+ +T + ++ D + KL+ +S + ++
Sbjct: 420 INSYI-----GKPAVNG--CRINNSTINYEKIKNIRIDGQKSRLRNKLSSRPYDSGFTED 472
Query: 463 H-----AVSDFKLSKSQIRNFEVIQQVDLKFILVK-------SGGTLLMLDQHACHERIL 510
+ ++DF +S+S + +EVI QVD KFIL++ + L+++DQHAC ERI
Sbjct: 473 YDSIGKTITDFSISRSVLAKYEVINQVDKKFILIRCLDQSIHNCPLLVLVDQHACDERIR 532
Query: 511 VENMLKETIIKCMNKCFNYVKLNMK---MNISAEEAGWFRESIPEFDTWGIVLEIKDIDT 567
+E + + + + F V ++K + + EA F+ EF WGI E +
Sbjct: 533 LEELFYSLLTEVVTGTF--VARDLKDCCIEVDRTEADLFKHYQSEFKKWGIGYETIEGTM 590
Query: 568 RSSVIELIKAPEFFHEKIKHDSAFLKHVLLQHIYDLRSSKRRRITQLMKEQHSSNK---W 624
+S++E+ PE K D +LK VLLQH +DL+ K+ + E ++S W
Sbjct: 591 ETSLLEIKTLPEMLTSKYNGDKDYLKMVLLQHAHDLKDFKKLPMDLSHFENYTSVDKLYW 650
Query: 625 WIMVPHMPRVYTEIINSKSCRSAIMFGTSLSRTECDVMISDLSKCQQPFHCAHGRPSVVP 684
W +P V+ EI+NSK+CRSA+MFG L+R EC ++IS LS+C PF CAHGRPS+VP
Sbjct: 651 WKYSSCVPTVFHEILNSKACRSAVMFGDELTRQECIILISKLSRCHNPFECAHGRPSMVP 710
Query: 685 IVEI 688
I E+
Sbjct: 711 IAEL 714
>Hs7657337 [L] KOG1977 DNA mismatch repair protein - MLH3 family
Length = 1429
Score = 117 bits (292), Expect = 8e-26
Identities = 101/387 (26%), Positives = 176/387 (45%), Gaps = 33/387 (8%)
Query: 3 IKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERFIIEVQDNGFGI 62
IK L V ++L+S ++ S V EL NS+DA+A + V +N E F ++V DNGFG+
Sbjct: 2 IKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFGM 61
Query: 63 TPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLIISKSKDYSGIWAR 122
D+ +G TSK S+Q L YGFRGEAL + + + IS K+ R
Sbjct: 62 GSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKN------R 115
Query: 123 ELPAPAFISDEGKF-----PLMKGALSGTVIKISDVFYNYPVRRKMMEKQSISDLVSAIR 177
+ + GK + A +GT + + ++FY PVRRK M+ + + +R
Sbjct: 116 TMKTFVKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFE---KVR 172
Query: 178 TEILTVLIKFPTLDVSVFINQQLRISSIAVSTLEPYPKQLDTC--FHNIFGEILPRKQLK 235
I + + P++ S+ + ++ S + PK D C F I+G + ++L+
Sbjct: 173 QRIEALSLMHPSISFSL-------RNDVSGSMVLQLPKTKDVCSRFCQIYG-LGKSQKLR 224
Query: 236 FVSASFKSHTVKGIVSINPIQSKDYQYIFINGRKYSDSRFFSAVNKLFQSTKYVEKNWDS 295
+S +K + G +S +K+ Q++F+N R ++ ++ L + + K +
Sbjct: 225 EISFKYKEFELSGYISSEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNG 284
Query: 296 YSVKSVGSPY------SAYPLFIIGCEVPLEISDLIQDPGKTIFQSGTLKTLCPLILNVM 349
+ + + S Y +++I + D+ +P KT+ + TL I +
Sbjct: 285 PTSRQMNSSLRHRSTPELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGV 344
Query: 350 SSFLKH--LGYE-PGVDVSTFDNSSYF 373
FLK L E G D+ F + F
Sbjct: 345 KMFLKQEKLFVELSGEDIKEFSEDNGF 371
Score = 58.2 bits (139), Expect = 4e-08
Identities = 56/241 (23%), Positives = 103/241 (42%), Gaps = 30/241 (12%)
Query: 456 ESSYLKNHAVS-DFKLSKSQIRNFEVIQQVDLKFILVKSGGTLLMLDQHACHERILVEN- 513
ES +K H + ++ +K I + +V+QQVD KFI + +E+ +
Sbjct: 1166 ESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFIACLMSTKTEENGEADSYEKQQAQGS 1225
Query: 514 ----MLKETIIKCMNKCFNYVKLNMKMNISAEEAGW-FRESIPEFDTWGIVLEIKDIDTR 568
+L T+I L + + W + +++ + LE DT
Sbjct: 1226 GRKKLLSSTLIP---------PLEITVTEEQRRLLWCYHKNLEDLG-----LEFVFPDTS 1271
Query: 569 SSVIELIKAPEFFHEKIKHDSAFLKHVLLQHIYDLRSSKRRRITQLMKEQHSSNKWWIMV 628
S++ + K P F E+ ++ + + + I + ++ + Q +
Sbjct: 1272 DSLVLVGKVPLCFVEREANELRRGRSTVTKSIVEEFIREQLELLQTTGGIQGT------- 1324
Query: 629 PHMPRVYTEIINSKSCRSAIMFGTSLSRTECDVMISDLSKCQQPFHCAHGRPSVVPIVEI 688
+P +++ S++C AI F LS E +I LS CQ PF CAHGRPS++P+ +I
Sbjct: 1325 --LPLTVQKVLASQACHGAIKFNDGLSLQESCRLIEALSSCQLPFQCAHGRPSMLPLADI 1382
Query: 689 N 689
+
Sbjct: 1383 D 1383
>Hs4557757 [L] KOG1979 DNA mismatch repair protein - MLH1 family
Length = 756
Score = 98.2 bits (243), Expect = 4e-20
Identities = 83/300 (27%), Positives = 147/300 (48%), Gaps = 30/300 (10%)
Query: 3 IKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERF-IIEVQDNGFG 61
I+RLD+TV +R+ + E + ++E+++N +DA +T I+V + +I++QDNG G
Sbjct: 8 IRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTG 67
Query: 62 ITPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLIISKSKD----YS 117
I DL+++ TSKL+S + L +IS+YGFRGEAL + + V I +K+ D Y
Sbjct: 68 IRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYR 127
Query: 118 GIWA-RELPAPAFISDEGKFPLMKGALSGTVIKISDVFYNYPVRRKMMEKQSISDLVSAI 176
++ +L AP P GT I + D+FYN RRK ++ S
Sbjct: 128 ASYSDGKLKAP---------PKPCAGNQGTQITVEDLFYNIATRRKALKNPSEE------ 172
Query: 177 RTEILTVLIKFPTLDVSVFINQQLRISSIAVSTLEPYPKQLDTCFHNIFGEILPRKQLKF 236
+IL V+ ++ + + + + + ++A P +D +IFG + R+ ++
Sbjct: 173 YGKILEVVGRYSVHNAGISFSVKKQGETVADVRTLPNASTVDN-IRSIFGNAVSRELIEI 231
Query: 237 ----VSASFKSHTVKGIVSINPIQSKDYQYIFINGRKYSDSRFFSAVNKLFQSTKYVEKN 292
+ +FK + I + N K +FIN R + A+ ++ + Y+ KN
Sbjct: 232 GCEDKTLAFKMNGY--ISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAA--YLPKN 287
>ECU05g0300 [L] KOG1979 DNA mismatch repair protein - MLH1 family
Length = 563
Score = 97.8 bits (242), Expect = 5e-20
Identities = 57/168 (33%), Positives = 94/168 (55%), Gaps = 7/168 (4%)
Query: 1 MSIKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERFIIEVQDNGF 60
M IKRL V SR+ + E + +++E ++NS+DA++T I + + + + V+D+G
Sbjct: 1 MEIKRLPSDVISRISAGEVITRPYNILKETIENSLDANSTHITIKMEQDGLTLTVEDDGD 60
Query: 61 GITPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLIISKSKDYSGIW 120
GI SD LL TSKL ++L ++SSYGFRGEAL + +C+++ + SK ++
Sbjct: 61 GIHESDFELLCKQYCTSKLTKEEELFSLSSYGFRGEALSSISRCARIKVRSKRRE----- 115
Query: 121 ARELPAPAFISDEGKFPLM-KGALSGTVIKISDVFYNYPVRRKMMEKQ 167
E+ A D + G GT+++I ++FYN VR K K+
Sbjct: 116 -GEIGYEAVYRDTEMITIKGVGMKDGTIVEIKNIFYNNKVREKHFSKK 162
>CE19915 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 805
Score = 95.5 bits (236), Expect = 2e-19
Identities = 104/415 (25%), Positives = 173/415 (41%), Gaps = 65/415 (15%)
Query: 3 IKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERF-IIEVQDNGFG 61
I+R+ V+ RL + + VVS ++ +R+L+ NS+DA +T I + + F IEVQDNG G
Sbjct: 6 IERISKEVAERLTTAQVVVSLSSAIRQLIDNSIDAGSTIIDIRVKNNGFESIEVQDNGSG 65
Query: 62 ITPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLIISKSKDYSGIWA 121
I + + L + TSKL +++ GFRGEAL+ + S V I +++ D
Sbjct: 66 IEARNFDALCKPHSTSKLTQFSDFDKLATLGFRGEALNALCTVSSVSIFTRASD------ 119
Query: 122 RELPAPAFISDEGKFPLMKGALS--GTVIKISDVFYNYPVRRKMMEKQSISDLVSAIRT- 178
E+ G + A GT I ++ +F PVRRK +E+ + V + T
Sbjct: 120 TEIGTRLTYDHSGNIICRQSAARELGTTIIVNKLFETLPVRRKELERSQKREFVKLLSTV 179
Query: 179 ----------EIL---------TVLIKFPTLDVSV--------FINQQLRISSIAVSTLE 211
+IL T LI P S+ I +++ S I +
Sbjct: 180 QSFALLCPHIKILCTNNINGKKTNLICTPGGTTSIQDVVANLFGIARKIENSKIGSGLIP 239
Query: 212 PYPKQLDTCFHNIFGEILPRKQLKFVSASFKSHTVKGIVSINP----IQSKDYQYIFING 267
Q D I +P +++ F F ++G VS + D Q+++IN
Sbjct: 240 IQQNQPDVEIMTIHS--VPMEEMHF----FDLFKIRGFVSSCEHGCGRGTSDRQFVYINN 293
Query: 268 RKYSDSRFFSAVNKLFQSTKYVEKNWDSYSVKSVGSPYSAYPLFIIGCEVPLEISDLIQD 327
R SR S +N +++ + YP+ ++ +VP E D+
Sbjct: 294 RPVEYSRVCSVINDVYKQFNKKQ-----------------YPIIVLFIDVPPEKIDVNVT 336
Query: 328 PG-KTIFQSGTLKTLCPLILNVMSSFLKHLGYEPGVDVSTFDNSSYFETAHYFTN 381
P KT+ L + ++M ++LK +G V S D + F+N
Sbjct: 337 PDKKTVMLEKERHLLAVVRASMMKTYLKIVGSHSTVRSSVEDRRIMNLSQQSFSN 391
>At4g09140 [L] KOG1979 DNA mismatch repair protein - MLH1 family
Length = 737
Score = 94.4 bits (233), Expect = 5e-19
Identities = 102/433 (23%), Positives = 186/433 (42%), Gaps = 60/433 (13%)
Query: 3 IKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERF-IIEVQDNGFG 61
I+RL+++V +R+ + E + + V+ELV+NS+DAD++ I V + +I+V D+G G
Sbjct: 29 IQRLEESVVNRIAAGEVIQRPVSAVKELVENSLDADSSSISVVVKDGGLKLIQVSDDGHG 88
Query: 62 ITPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLIISKSKDY----- 116
I DL +L + TSKL + L ++SS GFRGEAL M + V + + +K
Sbjct: 89 IRREDLPILCERHTTSKLTKFEDLFSLSSMGFRGEALASMTYVAHVTVTTITKGQIHGYR 148
Query: 117 ----SGIWARELPAPAFISDEGKFPLMKGALSGTVIKISDVFYNYPVRRKMMEKQSISDL 172
G+ E P A+ GT I + ++FYN RRK + Q+ +D
Sbjct: 149 VSYRDGVMEHE-------------PKACAAVKGTQIMVENLFYNMIARRKTL--QNSADD 193
Query: 173 VSAIRTEILTVLIKFPTLDVSVFINQQLRISSIAVSTLEPYPKQLDTCFHNIFGEILPRK 232
I + + I + + S + ++ +V + P +LD+ +++G + +
Sbjct: 194 YGKIVDLLSRMAIHYNNVSFSCRKHGAVKADVHSVVS----PSRLDS-IRSVYGVSVAKN 248
Query: 233 QLKFVSASFKS----HTVKGIVS-INPIQSKDYQYIFINGRKYSDSRFFSAVNKLFQSTK 287
+K +S S ++G +S N + K +FIN R S A+ ++ +T
Sbjct: 249 LMKVEVSSCDSSGCTFDMEGFISNSNYVAKKTILVLFINDRLVECSALKRAIEIVYAAT- 307
Query: 288 YVEKNWDSYSVKSVGSPYSAYPLFIIGCEVPLEISDLIQDPGKTIFQSGTLKTLCPLILN 347
P ++ P + +P E D+ P K + + +I +
Sbjct: 308 ---------------LPKASKPFVYMSINLPREHVDINIHPTKKEVSLLNQEIIIEMIQS 352
Query: 348 VMSSFLKHLGYEPGVDVSTFDNSSYFETAHYFTNTKRVELAVKPTNKHANGNRVHKPQNN 407
+ L++ D TF + Y +T + + P ++ +G + K N
Sbjct: 353 EVEVKLRNAN-----DTRTFQE----QKVEYIQSTLTSQKSDSPVSQKPSGQKTQKVPVN 403
Query: 408 KVLEILKSPPRTR 420
K++ S P R
Sbjct: 404 KMVRTDSSDPAGR 416
>YNL082w [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 904
Score = 90.5 bits (223), Expect = 8e-18
Identities = 90/380 (23%), Positives = 166/380 (43%), Gaps = 58/380 (15%)
Query: 3 IKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKV---DINTERFIIEVQDNG 59
I +++D R+ S + + T V+ELV NS+DA+A +I++ D E IE DNG
Sbjct: 35 IHQINDIDVHRITSGQVITDLTTAVKELVDNSIDANANQIEIIFKDYGLES--IECSDNG 92
Query: 60 FGITPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLIISKSKDYSGI 119
GI PS+ L + TSK+ Q + + + GFRGEAL + +K+ +I+ + S
Sbjct: 93 DGIDPSNYEFLALKHYTSKIAKFQDVAKVQTLGFRGEALSSLCGIAKLSVITTT---SPP 149
Query: 120 WARELPAPAFISDEGKFPLMKGALSGTVIKISDVFYNYPVRRKMME---KQSISDLVSAI 176
A +L K + GT + +S +F+N PVR+K K+ + ++ I
Sbjct: 150 KADKLEYDMVGHITSKTTTSRN--KGTTVLVSQLFHNLPVRQKEFSKTFKRQFTKCLTVI 207
Query: 177 R-TEILTVLIKFPTLDVSVFINQQLRISSIAVSTLEPYPKQLDTCFH----------NIF 225
+ I+ IKF +++ + L +S++ S++ K + + F ++
Sbjct: 208 QGYAIINAAIKFSVWNITPKGKKNLILSTMRNSSMR---KNISSVFGAGGMRGLEEVDLV 264
Query: 226 GEILPRKQL---------KFVSASFKSHTVKGIVSINPI----QSKDYQYIFINGRKYSD 272
++ P K F+ +K VKG +S N SKD Q+I++N R
Sbjct: 265 LDLNPFKNRMLGKYTDDPDFLDLDYKIR-VKGYISQNSFGCGRNSKDRQFIYVNKRPVEY 323
Query: 273 SRFFSAVNKLFQSTKYVEKNWDSYSVKSVGSPYSAYPLFIIGCEVPLEISDLIQDPGKTI 332
S N+++++ V+ +P + E+P+ + D+ P K +
Sbjct: 324 STLLKCCNEVYKTFNNVQ-----------------FPAVFLNLELPMSLIDVNVTPDKRV 366
Query: 333 FQSGTLKTLCPLILNVMSSF 352
+ + + +S +
Sbjct: 367 ILLHNERAVIDIFKTTLSDY 386
Score = 66.2 bits (160), Expect = 2e-10
Identities = 56/237 (23%), Positives = 109/237 (45%), Gaps = 33/237 (13%)
Query: 470 LSKSQIRNFEVIQQVDLKFILVK----SGGTLLMLDQHACHERILVENMLKETIIKCMNK 525
+SK+ + EV+ Q +L FI+V + L ++DQHA E+ E + T+ K
Sbjct: 697 VSKNDFKKMEVVGQFNLGFIIVTRKVDNKYDLFIVDQHASDEKYNFETLQAVTVFKSQK- 755
Query: 526 CFNYVKLNMKMNISAEEAGWFRESIPEFDTWGIVLEIKDIDTRSSVIELIKAPEFFHEKI 585
+ + + +S + +++P F+ G L+I + + S ++L+ P
Sbjct: 756 ----LIIPQPVELSVIDELVVLDNLPVFEKNGFKLKIDEEEEFGSRVKLLSLP------- 804
Query: 586 KHDSAFLKHVLLQHIYDLRSSKRRRITQLMKEQHSSNKWWIMVPHMPRVYTEIINSKSCR 645
Q ++DL + L+KE + I + ++ ++CR
Sbjct: 805 ---------TSKQTLFDLGDFNE--LIHLIKEDGGLRRDNIRCSKIRSMFA----MRACR 849
Query: 646 SAIMFGTSLSRTECDVMISDLSKCQQPFHCAHGRPSVVPIVEINDSIFGFSDKDYEI 702
S+IM G L++ ++ +LS+ +P++C HGRP++ ++E+ D + KDYEI
Sbjct: 850 SSIMIGKPLNKKTMTRVVHNLSELDKPWNCPHGRPTMRHLMELRD--WSSFSKDYEI 904
>SPAC19G12.02c [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 794
Score = 89.7 bits (221), Expect = 1e-17
Identities = 82/351 (23%), Positives = 156/351 (44%), Gaps = 32/351 (9%)
Query: 2 SIKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERF-IIEVQDNGF 60
++K +D ++ S + + + V+ELV+NS+D+ AT I++ IEV DNG
Sbjct: 3 TVKPIDANTVHKICSGQVITDVASAVKELVENSLDSGATTIEIRFKNYGINSIEVVDNGS 62
Query: 61 GITPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLIISKSKDYSGIW 120
GI D +G + TSK+ + L A+ ++GFRGEAL + +V+I + +++ +
Sbjct: 63 GIDAGDYESIGKKHFTSKITDFEDLEALQTFGFRGEALSSLCAVGQVIISTATQNEAPKG 122
Query: 121 AR-ELPAPAFISDEGKFPLMKGALSGTVIKISDVFYNYPVRRKMMEKQSISDLVSAIRTE 179
+ L + D+ P + GT + ++D+F PVRRK++EK + AI
Sbjct: 123 VQLNLDHEGSLKDKLTIPFQR----GTSVMVNDLFCTLPVRRKLLEKNYKREFSKAI--- 175
Query: 180 ILTVLIKFPTLDVS--VFINQQLRISSIAVSTLEPYPKQLDTCFHNIFGEILPRKQLKFV 237
++L + T+ + + Q + S + K + N+FG + + +
Sbjct: 176 --SLLQAYATISTNKRFMVYHQTKNSGKLLQLSTNSNKDMKLNIMNVFGTKVSSSLIPWN 233
Query: 238 SASFKSHTVKGIVSINPIQSKDYQYIFINGRKYSDSRFFSAVNKLFQSTKYVEKNWDSYS 297
+ + + V + S + Q +FIN R + + + ++F+ YS
Sbjct: 234 DGIIEGYISRPHVG-STRASNERQMLFINRRLVNLPKIARVIQEVFK----------PYS 282
Query: 298 VKSVGSPYSAYPLFIIGCEVPLEISD------LIQDPGKTIFQSGTLKTLC 342
+ SP+ A L I + + +S L ++ F +L+ LC
Sbjct: 283 MAQ--SPFFAINLRITNGTIDINVSPDKKSVFLSEEDSIIEFIKNSLQNLC 331
>YMR167w [L] KOG1979 DNA mismatch repair protein - MLH1 family
Length = 769
Score = 89.4 bits (220), Expect = 2e-17
Identities = 53/172 (30%), Positives = 91/172 (52%), Gaps = 11/172 (6%)
Query: 1 MSIKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERF-IIEVQDNG 59
+ IK LD +V +++ + E ++S ++E+++NS+DA+AT I + + ++++ DNG
Sbjct: 3 LRIKALDASVVNKIAAGEIIISPVNALKEMMENSIDANATMIDILVKEGGIKVLQITDNG 62
Query: 60 FGITPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLIISKSKDYSGI 119
GI +DL +L TSKL+ + L I +YGFRGEAL + ++V + +K K+
Sbjct: 63 SGINKADLPILCERFTTSKLQKFEDLSQIQTYGFRGEALASISHVARVTVTTKVKEDRCA 122
Query: 120 WARELPAPAFISDEGKF---PLMKGALSGTVIKISDVFYNYPVRRKMMEKQS 168
W EGK P GT I + D+F+N P R + + +
Sbjct: 123 WRVSYA-------EGKMLESPKPVAGKDGTTILVEDLFFNIPSRLRALRSHN 167
>CE18978 [L] KOG1979 DNA mismatch repair protein - MLH1 family
Length = 779
Score = 89.0 bits (219), Expect = 2e-17
Identities = 81/277 (29%), Positives = 123/277 (44%), Gaps = 22/277 (7%)
Query: 3 IKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDI-NTERFIIEVQDNGFG 61
I+RL V +R+ + E + ++ELV+NS+DA AT+I V++ N +++V DNG G
Sbjct: 25 IQRLPQDVVNRMAAGEVLARPCNAIKELVENSLDAGATEIMVNMQNGGLKLLQVSDNGKG 84
Query: 62 ITPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLIISKSKDYSGIWA 121
I D L+ TSKL+ + L + +YGFRGEAL + +KV I+SK D +
Sbjct: 85 IEREDFALVCERFATSKLQKFEDLMHMKTYGFRGEALASLSHVAKVNIVSKRADAKCAYQ 144
Query: 122 RELPAPAFISDEGKFPLMKGALSGTVIKISDVFYNYPVRRKMMEKQSISDLVSAIRTEIL 181
+D +GT I +D+FYN P RR M + + +L
Sbjct: 145 ANFLDGKMTADTKP----AAGKNGTCITATDLFYNLPTRRNKMTTH--GEEAKMVNDTLL 198
Query: 182 TVLIKFPTLDVSVFINQQLRISSIAVSTLEPYPKQLDTCFHNIFGEILP----RKQLKFV 237
I P + ++ NQ + L ++ ILP +LKF
Sbjct: 199 RFAIHRPDVSFALRQNQAGDFRTKGDGNFRDVVCNL--LGRDVADTILPLSLNSTRLKF- 255
Query: 238 SASFKSHTVKGIVSI------NPIQSKDYQYIFINGR 268
+F H K I S N S+ + +FINGR
Sbjct: 256 --TFTGHISKPIASATAAIAQNRKTSRSFFSVFINGR 290
>7304079 [L] KOG1979 DNA mismatch repair protein - MLH1 family
Length = 664
Score = 83.6 bits (205), Expect = 1e-15
Identities = 57/181 (31%), Positives = 98/181 (53%), Gaps = 16/181 (8%)
Query: 3 IKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERF-IIEVQDNGFG 61
I++LD+ V +R+ + E + ++EL++NS+DA +T I+V + ++++QDNG G
Sbjct: 10 IRKLDEVVVNRIAAGEIIQRPANALKELLENSLDAQSTHIQVQVKAGGLKLLQIQDNGTG 69
Query: 62 ITPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLIISKSKDYSGIWA 121
I DL ++ TSKL + L I+++GFRGEAL + + + I +K+ A
Sbjct: 70 IRREDLAIVCERFTTSKLTRFEDLSQIATFGFRGEALASISHVAHLSIQTKT-------A 122
Query: 122 RELPAPAFISDEGKF---PLMKGALSGTVIKISDVFYNYPVRRKMM-----EKQSISDLV 173
+E +GK P GT+I I D+FYN P RR+ + E Q +S+++
Sbjct: 123 KEKCGYKATYADGKLQGQPKPCAGNQGTIICIEDLFYNMPQRRQALRSPAEEFQRLSEVL 182
Query: 174 S 174
+
Sbjct: 183 A 183
>SPBC1703.04 [L] KOG1979 DNA mismatch repair protein - MLH1 family
Length = 684
Score = 82.8 bits (203), Expect = 2e-15
Identities = 122/532 (22%), Positives = 217/532 (39%), Gaps = 88/532 (16%)
Query: 3 IKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERF-IIEVQDNGFG 61
I+ LD V +++ + E + ++EL++NS+DA +T I V + ++++ DNG G
Sbjct: 9 IRPLDQLVINKIAAGEIIERPENAIKELIENSLDAGSTSIDVLLKDGGLKLLQITDNGSG 68
Query: 62 ITPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLIISKSKDYSGIWA 121
I DL L TSK+++ L + ++GFRGEAL + +KV +++K W
Sbjct: 69 IQYDDLPYLCQRFSTSKIDNFNDLQHLQTFGFRGEALASISHVAKVTVVTKLSSDIHAW- 127
Query: 122 RELPAPAFISDEGKFPLMKG---------ALSGTVIKISDVFYNYPVRRKMMEKQSISDL 172
AF D P+ G GTVI D+FYN R+ ++ S
Sbjct: 128 -----KAFYVDGALAPISPGMSPAPQPCAGKQGTVITAEDLFYNVRSRKSALKNGSEE-- 180
Query: 173 VSAIRTEILTVLIKFPTLDVSVFINQQLRISSIAVSTLEPYPKQLDTCFHNIFGEILPR- 231
I+ ++ K+ + V N + ++A +L + D H I+G PR
Sbjct: 181 ----FRRIMILVQKYAIHNDQVSFNCKKVGDTVASLSLSSRLSKADKIRH-IYG---PRV 232
Query: 232 -KQLKFVSASFKSHTVKGIVSINPIQSKDYQ------YIFINGRKYSDSRFFSAVNKLFQ 284
L+ S ++ G + I + D+Q +FIN R A+ + +
Sbjct: 233 ASHLRDFSLGEGQSSIVGFSANGFISNADFQDKKSNLILFINNRLVESVELRHALEETY- 291
Query: 285 STKYVEKNWDSYSVKSVGSPYSAYPLFIIGCEVPLEISDLIQDPGKTIFQSGTLKTLCPL 344
KY+ K G+ Y Y + + E D+ P K I + +
Sbjct: 292 -AKYLHK----------GASYFVY----LSLNMSPEQLDVNVHPSKRIVHFLYDQEIATS 336
Query: 345 ILNVMSSFLKHLGYEPGVDVSTFDNSSYFETAHYFTNTKRVELAVKPTNKHANGNRVHKP 404
I + + L+ E + S +NTK N ++ + +
Sbjct: 337 ICDKLGEILERTDTERSYPLQAMIPS--------ISNTK---------NAESSSQKAVRT 379
Query: 405 QNNKVLEILKSPPRTRGIFSRLLENTTGGRQCRDHHYDSEFDIQKLNLAGTESSYLKNHA 464
N ++++ PR R I S L +N Q ++YD+E I+K++ A + +A
Sbjct: 380 YEN---YLVRTDPRERSIKSMLSDNFL---QRSSNNYDNEI-IEKVDSANS-----NKNA 427
Query: 465 VSDFKLSKSQIRNFEVIQQ---VDLKFILVKSGGTLLMLDQHACHERILVEN 513
+D K ++ E++++ +DL+ I KS ++ H IL E+
Sbjct: 428 TNDIK----DLQTEEIVEEGNSIDLESI--KSLQKQVINSMHVLATNILTEH 473
>Hs4505911 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 932
Score = 81.3 bits (199), Expect = 5e-15
Identities = 91/397 (22%), Positives = 165/397 (40%), Gaps = 39/397 (9%)
Query: 3 IKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERFI-IEVQDNGFG 61
+K+L L S + + S +VV+EL++NS+DA AT + V + F IEV+DNG G
Sbjct: 1 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60
Query: 62 ITPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLIISKSKDYSGIWA 121
I D ++ TSK+ S + L +++YGFRGEAL + ++VLI +++ A
Sbjct: 61 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTA------A 114
Query: 122 RELPAPAFISDEGKFPLMKGAL--SGTVIKISDVFYNYPVRRKMME-KQSISDLVSAIRT 178
+ G K + GT + +F N PVR++ + D + I+
Sbjct: 115 DNFSTQYVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQD 174
Query: 179 EILTVLIKFPTLDVSVFIN------QQLRISSIAVSTLEPYPKQLDTCFHNIFGEILPRK 232
+++ I P L + VF++ Q+ R+S ++ + L T N
Sbjct: 175 LLMSFGILKPDLRI-VFVHNKAVIWQKSRVSDHKMALM----SVLGTAVMNNMESFQYHS 229
Query: 233 QLKFVSASFKSHTVKGIVSINPIQSKDYQYIFINGRKYSDSRFFSAVNKLFQSTKYVEKN 292
+ + S S + + + +IFIN R +
Sbjct: 230 EESQIYLSGFLPKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIR------------ 277
Query: 293 WDSYSVKSVGSPYSAYPLFIIGCEVPLEISDLIQDPGKTIFQSGTLKTLCPLILNVMSSF 352
Y++K + YP+F + +VP D+ P K+ +++ + N+M++
Sbjct: 278 -HHYNLKCLKESTRLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTC 336
Query: 353 LKHLGYEPGVDVSTFDNSSYFETAHYFTNTKRVELAV 389
Y P ++++N+ +A +K E V
Sbjct: 337 -----YGPLPSTNSYENNKTDVSAADIVLSKTAETDV 368
>At4g35520 [L] KOG1977 DNA mismatch repair protein - MLH3 family
Length = 1151
Score = 79.7 bits (195), Expect = 1e-14
Identities = 73/259 (28%), Positives = 119/259 (45%), Gaps = 41/259 (15%)
Query: 439 HHYDSEFDIQK--LNLAGTESSYLKNHAVSDFKLSKSQIRNFEVIQQVDLKFILVKSGGT 496
H D FDI L+L ES ++ +++ + + +V+QQVD K+I + + GT
Sbjct: 887 HGQDGVFDISSGLLHLRSDESLVPES-------INRHSLEDAKVLQQVDKKYIPIVACGT 939
Query: 497 LLMLDQHACHERILVENMLKETIIKCMNKCFNYVKLNMKMNISAEEAGW--FRESIPEFD 554
+ ++DQHA ERI +E E K +N L +K+ E G+ + +
Sbjct: 940 VAIVDQHAADERIRLE----ELRTKFINDALLIFVLTLKV---LPEMGYQLLQSYSEQIR 992
Query: 555 TWGIVLEIKDIDTRS-----SVIELIKAPEFFHEKIKHDSAFLKHVLLQHIYDLRSSKRR 609
WG + I + S S+I+ P + + +L ++ D+
Sbjct: 993 DWGWICNITVEGSTSFKKNMSIIQRKPTPITLNA--------VPCILGVNLSDV--DLLE 1042
Query: 610 RITQLMKEQHSSNKWWIMVPHMPRVYTEIINSKSCRSAIMFGTSLSRTECDVMISDLSKC 669
+ QL SS +P ++NSK+CR AIMFG SL +EC ++I L +
Sbjct: 1043 FLQQLADTDGSST--------IPPSVLRVLNSKACRGAIMFGDSLLPSECSLIIDGLKQT 1094
Query: 670 QQPFHCAHGRPSVVPIVEI 688
F CAHGRP+ VP+V++
Sbjct: 1095 SLCFQCAHGRPTTVPLVDL 1113
Score = 79.0 bits (193), Expect = 2e-14
Identities = 61/200 (30%), Positives = 92/200 (45%), Gaps = 16/200 (8%)
Query: 2 SIKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERFIIEVQDNGFG 61
+IK L + V ++S + VV ELV NS+DA ATK+ + + ++V D+G G
Sbjct: 3 TIKPLPEGVRHSMRSGIIMFDMARVVEELVFNSLDAGATKVSIFVGVVSCSVKVVDDGSG 62
Query: 62 ITPSDLNLLGGHNITSKLESLQQLPAIS-SYGFRGEALHLMLQCS----KVLIISKSKDY 116
++ DL LLG TSK + S ++GFRGEAL + S + I + Y
Sbjct: 63 VSRDDLVLLGERYATSKFHDFTNVETASETFGFRGEALASISDISLLEVRTKAIGRPNGY 122
Query: 117 SGIWARELPAPAFISDEGKFPLMKGALSGTVIKISDVFYNYPVRRKMMEKQSISDLVS-- 174
+ I D+ K SGT + + D+FY+ PVRRK M+ L S
Sbjct: 123 RKVMKGSKCLHLGIDDDRKD-------SGTTVTVRDLFYSQPVRRKYMQSSPKKVLESIK 175
Query: 175 --AIRTEILTVLIKFPTLDV 192
R ++ + F LD+
Sbjct: 176 KCVFRIALVHSNVSFSVLDI 195
>At4g02460 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 779
Score = 72.4 bits (176), Expect = 2e-12
Identities = 78/304 (25%), Positives = 134/304 (43%), Gaps = 51/304 (16%)
Query: 3 IKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDI-NTERFIIEVQDNGFG 61
I+ ++ V R+ S + ++ ++ V+ELV+NS+DA AT I++++ + +V DNG G
Sbjct: 17 IRPINRNVIHRICSGQVILDLSSAVKELVENSLDAGATSIEINLRDYGEDYFQVIDNGCG 76
Query: 62 ITPSD-----------LNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLII 110
I+P++ ++L + TSKLE L +++YGFRGEAL + + +
Sbjct: 77 ISPTNFKVCVQILRRTFDVLALKHHTSKLEDFTDLLNLTTYGFRGEALSSLCALGNLTVE 136
Query: 111 SKSKDYSGIWARELPAPAFISDEGKFPLMKGALSGTVIKISDVFYNYPVRRKMMEKQSIS 170
+++K+ ++ E K GT + + +F N PVR K ++
Sbjct: 137 TRTKNEPVATLLTFDHSGLLTAEKK----TARQIGTTVTVRKLFSNLPVRSKEFKRN--- 189
Query: 171 DLVSAIRTEILTVLIKFPTLDVSVFINQQLRISSIAVSTLEPYPKQLDTCFHNIFGEILP 230
IR E ++ L+ I + +R + +T PK + N G
Sbjct: 190 -----IRKEYGKLV---SLLNAYALIAKGVRF--VCSNTTGKNPKSV---VLNTQGR--- 233
Query: 231 RKQLKFVSASFKSH--TVKGIVSINPIQS------KDYQYIFINGRKYSDSRFFSAVNKL 282
S K + TV GI + +Q D QY FINGR + VN+L
Sbjct: 234 --------GSLKDNIITVFGISTFTSLQPGTGRNLADRQYFFINGRPVDMPKVSKLVNEL 285
Query: 283 FQST 286
++ T
Sbjct: 286 YKDT 289
>7303075 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 899
Score = 72.4 bits (176), Expect = 2e-12
Identities = 47/165 (28%), Positives = 85/165 (51%), Gaps = 13/165 (7%)
Query: 3 IKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERF-IIEVQDNGFG 61
IK + ++ S + V+S V+ELV+NS+DA AT +++ + + +EV DNG G
Sbjct: 27 IKAIGKDTVHKICSGQVVLSLAVAVKELVENSIDAGATLVEIKLKDQGLQSVEVSDNGSG 86
Query: 62 ITPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLIISKSKDYSGIWA 121
+ +L + TSK+ L + ++GFRGEAL + S ++I ++ K +
Sbjct: 87 VEEMNLEGMTAKYHTSKIREFVDLLGVETFGFRGEALSSLCALSDMVIQTRHK------S 140
Query: 122 RELPAPAFISDEGKF----PLMKGALSGTVIKISDVFYNYPVRRK 162
++ + EG+ P +G GT + ++++F PVRR+
Sbjct: 141 TDVGVKVELDHEGRIKKRSPCARGV--GTTVLLANLFSTLPVRRR 183
>ECU11g1260 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 630
Score = 70.1 bits (170), Expect = 1e-11
Identities = 62/221 (28%), Positives = 108/221 (48%), Gaps = 30/221 (13%)
Query: 3 IKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERFIIEVQDNGFGI 62
I++L + V R+++ SV S VV+EL++N++D+ T I++ ++ I V+DNG GI
Sbjct: 2 IRKLPEDVGKRIRAQRSVQSIYIVVKELIENAIDSGCTWIRILVDD---AITVEDNGCGI 58
Query: 63 TPSDLNLLGGHNITSKLESLQQLPAIS------SYGFRGEALHLMLQCSKVLIISKSKDY 116
SDL+ +G TSK + + SYGFRG+AL + + + IIS+S+
Sbjct: 59 --SDLDKVGVEGATSKESMAYYVLGYADRVEKFSYGFRGQALSCLAEVCDLEIISRSEH- 115
Query: 117 SGIWARELPAPAFISDEGKFPLMKGALS-GTVIKISDVFYNYPVRRKMME---KQSISDL 172
+ A D + K A GT + + ++F N P+RR M + K+ + +
Sbjct: 116 ---------SFALRKDFSTNAISKCARERGTTVHVRNLFKNCPLRRPMADSGLKRDLGKI 166
Query: 173 VSAIRTEILTVLIKFPTLDVSVFINQQLRISSIAVSTLEPY 213
S I + I F ++F +++ +S T+ Y
Sbjct: 167 CSLIESYRCANKINF-----TLFHKRKVLLSCGGYETVREY 202
>Hs4505913 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 862
Score = 67.0 bits (162), Expect = 9e-11
Identities = 50/176 (28%), Positives = 82/176 (46%), Gaps = 25/176 (14%)
Query: 2 SIKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERF-IIEVQDNGF 60
+IK +D ++ S + V+S + V+ELV+NS+DA AT I + + +IEV DNG
Sbjct: 14 AIKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEVSDNGC 73
Query: 61 GITPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLMLQCSKVLIISKSK------ 114
G+ + L + TSK++ L + ++GFRGEAL + S V I +
Sbjct: 74 GVEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKVGT 133
Query: 115 ----DYSGIWARELPAPAFISDEGKFPLMKGALSGTVIKISDVFYNYPVRRKMMEK 166
D++G ++ P P GT + + +F PVR K ++
Sbjct: 134 RLMFDHNGKIIQKTPYP--------------RPRGTTVSVQQLFSTLPVRHKEFQR 175
>YLR035c [R] KOG0017 FOG: Transposon-encoded proteins with TYA reverse
transcriptase integrase domains in various combinations
Length = 695
Score = 57.0 bits (136), Expect = 1e-07
Identities = 34/104 (32%), Positives = 57/104 (54%), Gaps = 3/104 (2%)
Query: 1 MSIKRLDDTVSSRLKSHESVVSTTAVVRELVQNSVDADATKIKVDINTERF---IIEVQD 57
M+I +L ++ S + A VREL+ NS+D+ A K+ +D+++ I V+D
Sbjct: 1 MTIHQLSPESQWKIVSSSFIYGPVAAVRELLDNSIDSGAKKVFIDVDSTTGGCEYISVKD 60
Query: 58 NGFGITPSDLNLLGGHNITSKLESLQQLPAISSYGFRGEALHLM 101
+G G+ D + TSK+ SL + +++ GFRGEAL L+
Sbjct: 61 DGSGVDIIDRPSMCLEYTTSKMSSLGDISILTTLGFRGEALFLL 104
>Hs22046611 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 199
Score = 51.6 bits (122), Expect = 4e-06
Identities = 41/148 (27%), Positives = 66/148 (43%), Gaps = 25/148 (16%)
Query: 30 LVQNSVDADATKIKVDINTERF-IIEVQDNGFGITPSDLNLLGGHNITSKLESLQQLPAI 88
+V+NS+DA AT I + + +IEV NG G+ + L + TSK++ L +
Sbjct: 1 MVENSLDAGATNIDLKLKDYGMDLIEVSGNGCGVEEENFEGLTLKHHTSKIQEFADLTRV 60
Query: 89 SSYGFRGEALHLMLQCSKVLIIS---KSK-------DYSGIWARELPAPAFISDEGKFPL 138
++GFRGEAL + S V I + +K D+ G ++ P P
Sbjct: 61 ETFGFRGEALSSLCALSDVTISTCHVSAKVGTRLVFDHDGKIIQKTPYP----------- 109
Query: 139 MKGALSGTVIKISDVFYNYPVRRKMMEK 166
GT + + +F PVR K ++
Sbjct: 110 ---HPRGTTVSVKQLFSTLPVRHKEFQR 134
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.136 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,692,213
Number of Sequences: 60738
Number of extensions: 1730958
Number of successful extensions: 4191
Number of sequences better than 1.0e-05: 20
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 4119
Number of HSP's gapped (non-prelim): 43
length of query: 704
length of database: 30,389,216
effective HSP length: 113
effective length of query: 591
effective length of database: 23,525,822
effective search space: 13903760802
effective search space used: 13903760802
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)