ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2578 check: MH E KOG2455 Amino acid transport and metabolism Delta-1-pyrroline-5-carboxylate dehydrogenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII2578 903888 905615 576
(576 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 877 0.0
SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrog... 563 e-160
Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 439 e-123
7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 422 e-118
CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 419 e-117
7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 349 7e-96
7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 256 5e-68
Hs21361176 [C] KOG2450 Aldehyde dehydrogenase 158 2e-38
HsM4502031 [C] KOG2450 Aldehyde dehydrogenase 158 2e-38
YER073w [C] KOG2450 Aldehyde dehydrogenase 152 1e-36
Hs4502041 [C] KOG2450 Aldehyde dehydrogenase 151 3e-36
YMR169c [C] KOG2450 Aldehyde dehydrogenase 150 4e-36
At1g23800 [C] KOG2450 Aldehyde dehydrogenase 150 4e-36
Hs10835045 [C] KOG2450 Aldehyde dehydrogenase 147 6e-35
YMR170c [C] KOG2450 Aldehyde dehydrogenase 145 2e-34
YPL061w [C] KOG2450 Aldehyde dehydrogenase 144 5e-34
CE23852 [C] KOG2450 Aldehyde dehydrogenase 144 5e-34
SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase 142 1e-33
YOR374w [C] KOG2450 Aldehyde dehydrogenase 141 2e-33
At3g48000 [C] KOG2450 Aldehyde dehydrogenase 140 7e-33
SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase 137 4e-32
Hs11436533 [C] KOG2450 Aldehyde dehydrogenase 137 6e-32
CE07233 [C] KOG2450 Aldehyde dehydrogenase 136 8e-32
7297513 [C] KOG2450 Aldehyde dehydrogenase 136 1e-31
At3g48170 [C] KOG2450 Aldehyde dehydrogenase 134 4e-31
7301355 [C] KOG2451 Aldehyde dehydrogenase 134 4e-31
Hs19923115 [C] KOG2450 Aldehyde dehydrogenase 132 1e-30
CE10542 [C] KOG2451 Aldehyde dehydrogenase 132 2e-30
CE29393 [C] KOG2450 Aldehyde dehydrogenase 131 3e-30
Hs4502033 [C] KOG2450 Aldehyde dehydrogenase 130 4e-30
Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 129 2e-29
At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 125 2e-28
SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase 124 4e-28
SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase 122 1e-27
CE06980 [C] KOG2450 Aldehyde dehydrogenase 122 1e-27
Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 121 3e-27
At1g79440 [C] KOG2451 Aldehyde dehydrogenase 121 3e-27
HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 120 7e-27
Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 117 4e-26
7301524 [C] KOG2450 Aldehyde dehydrogenase 116 1e-25
At1g74920 [C] KOG2450 Aldehyde dehydrogenase 115 2e-25
Hs4502047 [C] KOG2450 Aldehyde dehydrogenase 114 5e-25
Hs4507229 [C] KOG2451 Aldehyde dehydrogenase 113 7e-25
Hs12007648 [C] KOG2450 Aldehyde dehydrogenase 113 9e-25
At1g54100 [C] KOG2453 Aldehyde dehydrogenase 110 6e-24
CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 110 8e-24
CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 107 5e-23
7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 107 6e-23
Hs4557343 [C] KOG2453 Aldehyde dehydrogenase 106 8e-23
CE24573 [C] KOG2450 Aldehyde dehydrogenase 104 4e-22
CE01232 [C] KOG2453 Aldehyde dehydrogenase 104 4e-22
7293810 [C] KOG2453 Aldehyde dehydrogenase 102 1e-21
At2g24270 [C] KOG2450 Aldehyde dehydrogenase 96 1e-19
SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase 95 3e-19
YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G 91 6e-18
At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase 88 3e-17
YMR110c [C] KOG2456 Aldehyde dehydrogenase 80 6e-15
YBR006w [C] KOG2451 Aldehyde dehydrogenase 79 2e-14
7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 79 2e-14
SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase 73 1e-12
HsM4502035 [C] KOG2456 Aldehyde dehydrogenase 71 4e-12
Hs21359829 [C] KOG2456 Aldehyde dehydrogenase 71 4e-12
CE13415 [C] KOG2456 Aldehyde dehydrogenase 69 1e-11
At1g44170 [C] KOG2456 Aldehyde dehydrogenase 68 4e-11
7304212 [C] KOG2456 Aldehyde dehydrogenase 60 1e-08
CE27441 [C] KOG2456 Aldehyde dehydrogenase 59 2e-08
At5g62530 [C] KOG2451 Aldehyde dehydrogenase 59 3e-08
Hs4502043 [C] KOG2456 Aldehyde dehydrogenase 57 6e-08
Hs4557303 [C] KOG2456 Aldehyde dehydrogenase 57 1e-07
Hs18603595 [C] KOG2456 Aldehyde dehydrogenase 57 1e-07
Hs4502045 [C] KOG2456 Aldehyde dehydrogenase 50 9e-06
>YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 575
Score = 877 bits (2265), Expect = 0.0
Identities = 421/578 (72%), Positives = 496/578 (84%), Gaps = 5/578 (0%)
Query: 1 MLSSRIQLLRSSKRCVAQLSHIQPPKQIGNEPVKAFGSKDLVDWDLLRASLSKFKNSSLD 60
MLS+R KR +QL HI+PPK I NEPVK F + DL DWDLLRASL KFK+SSL+
Sbjct: 1 MLSARCLKSIYFKRSFSQLGHIKPPKHIRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLE 60
Query: 61 VPLVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDKWY 120
VPLVINGERIY D +R +F Q NPANH +VLANVTQAT +DV A++A+K AK WY
Sbjct: 61 VPLVINGERIY---DNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWY 117
Query: 121 KLPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYA 180
LP+Y+R+++F+KAADLI TKYRYDMLAATMLGQGKNVYQAEIDCITEL+DFFR+ VKYA
Sbjct: 118 NLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYA 177
Query: 181 NELYAQQPIESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALMGNTVVWKPSQ 240
++LYAQQP+ES+ G WN+AEYRPLEGFVYAV+PFNFTAIA NLIGAPALMGNTVVWKPSQ
Sbjct: 178 SDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALMGNTVVWKPSQ 237
Query: 241 NANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYG 300
A LSNYLL+TVLEEAGLP GV+NF+PG+ V+VT +VL+D +F ALHFTGST VFK LYG
Sbjct: 238 TAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYG 297
Query: 301 DIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRV 360
IQ GVV G YRDYPRI+GETGGKNFHL+HPSANI H+VLST+RG FEFQGQKCSA SR+
Sbjct: 298 KIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRL 357
Query: 361 YLPESKSEEFFRDLGGVL--SEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDD 418
YLPESKSEEF D+ G+L V P+NTSAS I+GG+L GF+GPVIHE SFDKL KVI+D
Sbjct: 358 YLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIED 417
Query: 419 AKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDV 478
AK DPELEI++GG +DKS+G+++ PT+IK P HPY+S EFFGPILTVYEYPD +F ++
Sbjct: 418 AKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEI 477
Query: 479 CELVDSTSQYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMS 538
C+++D+TSQY LTG+IFA+DR+AI+ ADEKLK+SAGNFYINDK TGAVV+QQWFGGARMS
Sbjct: 478 CDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMS 537
Query: 539 GTNDKAGSGNILNRFVSVRNIKENYYELTDYRYPSNYE 576
GT+DKAG NIL+RFVS+RN KEN+YELTD++YPSNYE
Sbjct: 538 GTDDKAGGPNILSRFVSIRNTKENFYELTDFKYPSNYE 575
>SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 548
Score = 563 bits (1452), Expect = e-160
Identities = 281/548 (51%), Positives = 383/548 (69%), Gaps = 11/548 (2%)
Query: 28 IGNEPVKAFGSKDLVDWDLLRASLSKFKNSSLDVPLVINGERIYYNDDGGKRGIFQQLNP 87
I NEP K +G +++A + +P++I+G+ + N G +Q P
Sbjct: 12 IKNEPPKHYGPNSADREGIVKAYKELEAELPVTIPVIIDGKEVETNTIG------EQRCP 65
Query: 88 ANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKYRYDML 147
H +V+A +A + V+ AI+A+ + K W LP+ +R+++F+KAA LI TKYRY ++
Sbjct: 66 FEHKKVVARYHRAGAKHVEDAIEAALRGKKVWESLPFADRSAIFLKAAHLISTKYRYKLM 125
Query: 148 AATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEYRPLEGF 207
AATM+GQGKN++QAEID E+ DF RFN KYA+ELYA QP E++PGVWNR EYRPLEGF
Sbjct: 126 AATMIGQGKNIWQAEIDAGMEIIDFLRFNTKYASELYASQPPENTPGVWNRMEYRPLEGF 185
Query: 208 VYAVTPFNFTAIAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFVP 267
VYA+TPFNFTAIAGNL AP LMGN V+ KPS +A LS+Y++ + EAGLP G + F+P
Sbjct: 186 VYAITPFNFTAIAGNLAAAPLLMGNVVLMKPSDHAVLSSYIVYQIFREAGLPAGALQFIP 245
Query: 268 GNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFH 327
G+AVEV+K + EFA LHFTGSTAVF+ L+G I + V NG YR YP+IVGETGGKNFH
Sbjct: 246 GDAVEVSKVCFNHPEFAGLHFTGSTAVFRSLWGTIGENVANGKYRTYPKIVGETGGKNFH 305
Query: 328 LIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNTS 387
L+H SA I +V++ +R AFE+QGQKCSA SR+Y+ + E FRD + +V+ +
Sbjct: 306 LVHSSAEIKSAVVNAVRAAFEYQGQKCSALSRLYVSKYAWENGFRD--ELTKQVKSLKVG 363
Query: 388 ASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYIQPTIIK 447
A D F+GPVIH+ SF+KL KV++ A +D E+E++ GG D S+G++++PT++
Sbjct: 364 APLT---DFANFVGPVIHQASFNKLKKVLESAASDSEIEVLAGGKADDSEGFFVEPTVLL 420
Query: 448 TTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDREAIKIADE 507
+ NP+H E FGP+L+VY Y D + VC+L+D+T+ YGLTGSIFA+DR ++ +
Sbjct: 421 SKNPKHDIFVNELFGPVLSVYVYEDDNLDAVCDLIDTTTPYGLTGSIFAQDRVVVRKLTD 480
Query: 508 KLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNILNRFVSVRNIKENYYELT 567
+L+ +AGNFYINDK TGAVV +Q FGGAR SGTNDKAGSG IL+RFVS R+IK+ +
Sbjct: 481 RLRNAAGNFYINDKCTGAVVGEQPFGGARASGTNDKAGSGMILSRFVSPRSIKDTFAYAD 540
Query: 568 DYRYPSNY 575
YPSN+
Sbjct: 541 SVLYPSNF 548
>Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 439 bits (1129), Expect = e-123
Identities = 234/545 (42%), Positives = 334/545 (60%), Gaps = 16/545 (2%)
Query: 27 QIGNEPVKAFGSKDLVDWDLLRASLSKFKNSSLDVPLVINGERIYYNDDGGKRGIFQQLN 86
++ NEPV AF ++ + D L+ +L K +P V+ E ++ +D + Q++
Sbjct: 31 KVANEPVLAF-TQGSPERDALQKALKDLKGRMEAIPCVMGDEEVWTSD------VQYQVS 83
Query: 87 PANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKYRYDM 146
P NH +A A + AI+A+ A+ +W P +RA +F+KAAD++ R ++
Sbjct: 84 PFNHGHKVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEI 143
Query: 147 LAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEYRPLEG 206
LA TM+GQGK V QAEID EL DFFRFN KYA EL QQPI P N YR LEG
Sbjct: 144 LAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPST-NSTVYRGLEG 202
Query: 207 FVYAVTPFNFTAIAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFV 266
FV A++PFNFTAI GNL GAPALMGN V+WKPS A L++Y + +L EAGLP ++ FV
Sbjct: 203 FVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFV 262
Query: 267 PGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNF 326
P + V S ++FTGS FK L+ + + + + +PR+ GE GGKNF
Sbjct: 263 PADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDR--FHTFPRLAGECGGKNF 320
Query: 327 HLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNT 386
H +H SA++ V TLR AFE+ GQKCSA SR+Y+P S + G +L E +
Sbjct: 321 HFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQI---KGRLLEEHSRIKV 377
Query: 387 SASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYIQPTII 446
D F VI SF ++ K ++ A++ P L I+ GG D S GY+++P I+
Sbjct: 378 GDP---AEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIV 434
Query: 447 KTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDREAIKIAD 506
++ +P+ P + +E FGP+L+VY YPD K+++ +LVDST+ YGLTG++F++D++ ++ A
Sbjct: 435 ESKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEAT 494
Query: 507 EKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNILNRFVSVRNIKENYYEL 566
+ L+ +AGNFYINDKSTG++V QQ FGGAR SGTNDK G + + R+ S + IKE + L
Sbjct: 495 KVLRNAAGNFYINDKSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPL 554
Query: 567 TDYRY 571
D+ Y
Sbjct: 555 GDWSY 559
>7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 574
Score = 422 bits (1086), Expect = e-118
Identities = 232/571 (40%), Positives = 344/571 (59%), Gaps = 25/571 (4%)
Query: 8 LLRSSKRCVAQLSHIQPPKQ--IGNEPVKAFGSKDLVDWDLLRASLSKFKNSSLDVPLVI 65
LL+SS RC+ + K I NEP+ + KD + L +L +S D+P+VI
Sbjct: 19 LLKSSTRCLGSVIPDLKLKDFPIANEPILGY-LKDSKERKALEQALKGTASSCEDIPIVI 77
Query: 66 NGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYY 125
G+ + + Q+ P +H LA+ A + ++ AI+ + + + KW ++
Sbjct: 78 GGKEYKTPE------VRYQVMPHDHQHKLASFYYADKKLIEKAIKTAVETQPKWDRVSIA 131
Query: 126 ERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYA 185
+R ++ KAADL+ T YR D+ AATMLGQ K QAEID EL DF R N + E+
Sbjct: 132 DRLKIWEKAADLMATTYRQDLNAATMLGQSKTAIQAEIDSAAELIDFIRMNAYFLKEVTK 191
Query: 186 QQPIESSPGVW-NRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALMGNTVVWKPSQNANL 244
QPI + V N YR ++GF+ AV+PFNFTAI GNL PALMGN V+WKPS A L
Sbjct: 192 YQPISENIKVTKNSLRYRGIDGFIAAVSPFNFTAIGGNLSYTPALMGNGVLWKPSDTAML 251
Query: 245 SNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQK 304
SN+++ ++ EAG+P+GVVNFVP + + + A ++FTGS F +L+ +
Sbjct: 252 SNWIIFKIMREAGVPDGVVNFVPADGPVFGDTITASPHLAGINFTGSVPTFNRLWKQVGN 311
Query: 305 GVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPE 364
+ N Y ++PR+ GE GGKNFH IH SA++ V ST+R AFE+ GQKCSA SR+Y+PE
Sbjct: 312 NIDN--YVNFPRLTGECGGKNFHFIHASADVESVVTSTIRSAFEYCGQKCSACSRMYVPE 369
Query: 365 SKSEEFFRDLGGVLSEVQPVNTSASKINGGDLH---GFIGPVIHEGSFDKLAKVIDDAKN 421
S + G++ E A+K+ GD+ F VI + +F ++ I+ AK
Sbjct: 370 SLWPQIKE---GLVCE-------AAKLKIGDVQDFSSFTSAVIDDKAFKRITGYIEHAKK 419
Query: 422 DPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCEL 481
P LEI+ GG + SKGY++ PTI+ + +P+ +++E FGP+L++Y Y ++ + +L
Sbjct: 420 SPNLEILAGGTYSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKESDLLETMKL 479
Query: 482 VDSTSQYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTN 541
V +++++ LTG++F +D + +K A ++ K +AGNFYINDKSTG+VV QQ FGG RMSGTN
Sbjct: 480 VHTSTKFALTGAVFGQDEDFVKCALQEFKMAAGNFYINDKSTGSVVGQQPFGGGRMSGTN 539
Query: 542 DKAGSGNILNRFVSVRNIKENYYELTDYRYP 572
DKAG + + R+ S ++IKE + L D YP
Sbjct: 540 DKAGGPHYILRWTSPQSIKETFVPLRDVNYP 570
>CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 419 bits (1076), Expect = e-117
Identities = 228/551 (41%), Positives = 337/551 (60%), Gaps = 22/551 (3%)
Query: 26 KQIGNEPVKAF--GSKDLVDWDLLRASLSKFKNSSLDVPLVINGERIYYNDDGGKRGIFQ 83
K+ NEP+ + GSK+ D L A+L+ + + +VPL I ++I + +
Sbjct: 30 KKKTNEPILEYRKGSKERQD---LEAALAFYSKNITEVPLRIGDKKITNKLEQ------K 80
Query: 84 QLNPANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKYR 143
Q+ P++H LA T AT E ++ AI + QA+ W + P ERA + ++AADL KYR
Sbjct: 81 QVIPSDHRSTLAKYTYATGEQIQEAIDVALQARGAWERKPLKERAEILLRAADLAAGKYR 140
Query: 144 YDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEYRP 203
+ A+TMLGQGKN+ QAEID EL DFFRFN +A EL +PI S+ N ++R
Sbjct: 141 MKLNASTMLGQGKNIIQAEIDAACELIDFFRFNAVFAMELEHYEPI-STKITKNTMQFRG 199
Query: 204 LEGFVYAVTPFNFTAIAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVV 263
+EGFV A+ PFNFTAI GNL APALMGN +WKPS A LSNY++ +LEEAG+P G++
Sbjct: 200 MEGFVAAIAPFNFTAIGGNLPTAPALMGNVSLWKPSNTAVLSNYIIYELLEEAGMPPGIL 259
Query: 264 NFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGG 323
+F+P + + + +A++FTGS FK ++ + + + N Y +P+++GE GG
Sbjct: 260 SFLPSDGPVFGDVITASPHLSAVNFTGSVPTFKTIWRKVAENLDN--YVTFPKLIGECGG 317
Query: 324 KNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQP 383
KNFH +HPSA++ T R A+E+ GQKCSA SR+Y P+S + + + E++
Sbjct: 318 KNFHFVHPSAHVDAVAAGTARSAWEYSGQKCSACSRMYAPKSIWPKILEKISAIHKEIK- 376
Query: 384 VNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPE-LEIVFGGFHDKSKGYYIQ 442
+ G + F+ VI + +F +L ID AK + +V GG D GY+I+
Sbjct: 377 ----LGDVRDGSV--FLSAVIDDKAFARLKAYIDFAKTGADGANVVLGGKCDDKTGYFIE 430
Query: 443 PTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDREAI 502
PT+I T+P+ L++E FGP++TV Y D+K ++V V + YGLTG++F++D+E +
Sbjct: 431 PTLITVTDPKSKLLTEEMFGPVVTVLVYEDSKVDEVLATVKDATPYGLTGAVFSQDKEFL 490
Query: 503 KIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNILNRFVSVRNIKEN 562
A + L+ + GN Y+NDKSTG++V QQ FGG+R+SGTNDKAG + R+ S IKE
Sbjct: 491 YRARDVLRDAVGNMYLNDKSTGSIVGQQPFGGSRLSGTNDKAGGPHYGLRWTSPLTIKET 550
Query: 563 YYELTDYRYPS 573
LTD++YPS
Sbjct: 551 SVSLTDWKYPS 561
>7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 1590
Score = 349 bits (895), Expect = 7e-96
Identities = 212/574 (36%), Positives = 314/574 (53%), Gaps = 40/574 (6%)
Query: 21 HIQPPKQIGNEPVKAF--GSKDLVDWDLLRASLSKFKNSSLDVPLVINGERIYYNDDGGK 78
H + + NE + + GSK+ + L +L N VP+VING+ +D
Sbjct: 38 HFTLDEMVANEKLLQYDEGSKERTE---LETALLGVLNRVEHVPIVINGQEFQAKED--- 91
Query: 79 RGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLI 138
FQQ+ P + + +A+ A ++ AI S +A+ KW K+ +R ++ +AA LI
Sbjct: 92 ---FQQVLPYDIQQPIAHYGHAHRVLIQMAIDKSVEAQVKWDKVRLSDRIDIWERAAMLI 148
Query: 139 CTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIES-SPGVWN 197
+YRY+++AATMLGQGK + QAE+D + EL DF R N + EL +PI N
Sbjct: 149 AGRYRYNIIAATMLGQGKTLRQAEMD-VAELVDFMRINPVFLRELANYEPIRDIQNNCRN 207
Query: 198 RAEYRPLEG-------------------FVYAVTPFNFTAIAGNLIGAPALMGNTVVWKP 238
R L G FV A++PFNFT IA NL PALMGN+V+WKP
Sbjct: 208 SMRLRGLSGGSPYNLYGFLSFYNFLFAGFVAAISPFNFTGIAANLAYTPALMGNSVIWKP 267
Query: 239 SQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQL 298
S +A LSNY + L EAG+P+GVVNFVP V + A ++FTG++ V K L
Sbjct: 268 SDSAILSNYFVFKALREAGVPDGVVNFVPAEETTFASVVTQHPKLAGINFTGTSTVLKVL 327
Query: 299 YGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATS 358
+ + + + Y++YPR+VGE GGKNFH +H SA +V T+R AFE+ GQKCS+ S
Sbjct: 328 WQLVAQNI--NFYQNYPRLVGEGGGKNFHFVHSSAEPETAVACTIRAAFEYAGQKCSSCS 385
Query: 359 RVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDD 418
+Y+PES + R+ ++ V A+ + F VI+ ++D++ +
Sbjct: 386 MLYVPESLWQNHIREPLLEITASLVVRQDATYCD-----SFCSAVINRRAYDRIYMWLRY 440
Query: 419 AKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDV 478
P +I+ GG DK +GYY+ PT++ + + +E PIL VY YPD K ++
Sbjct: 441 IDQSPSCQILVGGSCDKRRGYYVDPTVVLVKDLDNIICREELLAPILGVYVYPDHKLKET 500
Query: 479 CELVDSTSQYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMS 538
E V + +GLTGS+FA+D+ I+ A + + + GN +NDKSTG +V QQ FG M+
Sbjct: 501 MEKV-AQINHGLTGSVFAQDQNFIEEAYDAFRVNVGNLNVNDKSTGLMVGQQPFGAGHMT 559
Query: 539 GTNDKAGSGNILNRFVSVRNIKENYYELTDYRYP 572
GT+DK G+ + L R+ S + IKE+Y + YP
Sbjct: 560 GTSDKLGTPHSLLRWTSPQVIKESYKTHRNIFYP 593
>7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 560
Score = 256 bits (655), Expect = 5e-68
Identities = 167/521 (32%), Positives = 271/521 (51%), Gaps = 29/521 (5%)
Query: 46 LLRASLSKFKNSSLDVPLVINGERIYYNDDGGKRGIFQQLNPANHSEV-LANVTQATNED 104
L+ ++ + ++ L+VP +I + +Y D Q++ +H + LA+V A +
Sbjct: 49 LVNHAIQEIQHRPLEVPTIIGDDTVYTMDT-------QRVCCPHHLQTNLAHVYYANRKQ 101
Query: 105 VKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEID 164
++AAI+++ A+ W +P +R +++ +AA +I + + M+ K A D
Sbjct: 102 IEAAIKSALSAQGTWSLVPIAQRLAIWRRAATII-EEDELRLRVFLMMTLSKTADDATRD 160
Query: 165 CITELADFFRFNVKYANELYAQQ-PIESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNL 223
I L R N Y L + I+ V+ RP++GFV A+ PF A++ +L
Sbjct: 161 -IRRLLTSLRANADYLEHLSELRFEIQGDMNVFPSFHLRPMDGFVAALAPFESVALSSSL 219
Query: 224 IGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEF 283
PALMGNTV+W PS +YL+ +EAGLP+GV+NFVP N + + D+
Sbjct: 220 ALCPALMGNTVLWNPSLEVAPVSYLIFRAFQEAGLPSGVINFVPAN-----ERLFLDTIT 274
Query: 284 AALHFTG-STAVFKQLYGDIQKGVVNGL--YRDYPRIVGETGGKNFHLIHPSANIPHSVL 340
A+HF G +T Y + K V + + Y +PR+V E G+NFH +H SA + V
Sbjct: 275 DAVHFAGLNTQASAAFYRHVHKLVSDRMERYICFPRLVAECPGQNFHFVHASAKVESVVS 334
Query: 341 STLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHGFI 400
+T++ AF F GQ ++ SR+Y+P S +L ++ + S+ + I
Sbjct: 335 ATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVEATEQLTIGDPIESETD-------I 387
Query: 401 GPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEF 460
G ++H F ++ K++ KN +E + GG D S G ++ PTI++ ++P P L +
Sbjct: 388 GAMVHINDFRRMQKLLQRTKN---MEQLCGGSCDDSTGRFVDPTIVRVSDPLDPLLCEPC 444
Query: 461 FGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDREAIKIADEKLKYSAGNFYIND 520
GP L V+ Y D F + +L + S+Y L+GSIFA E I +L+ SA N Y+N+
Sbjct: 445 CGPFLPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSASNLYVNE 504
Query: 521 KSTGAVVAQQWFGGARMSGTNDKAGSGNILNRFVSVRNIKE 561
+ TG+ FGG R+SGTNDK+GS L R+ S I+E
Sbjct: 505 RCTGSTYGLTPFGGNRLSGTNDKSGSAYFLMRWSSPLLIEE 545
>Hs21361176 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 158 bits (400), Expect = 2e-38
Identities = 146/493 (29%), Positives = 234/493 (46%), Gaps = 46/493 (9%)
Query: 63 LVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQA---KDKW 119
+ IN E +++ GK+ F NPA E L V + EDV A++A++QA W
Sbjct: 23 IFINNE--WHDSVSGKK--FPVFNPATEEE-LCQVEEGDKEDVDKAVKAARQAFQIGSPW 77
Query: 120 YKLPYYERASVFMKAADLICTKYRYDMLAATM--LGQGKNVYQAEIDCITELADFFRFNV 177
+ ER + K ADLI R +L ATM + GK A ++ + R+
Sbjct: 78 RTMDASERGRLLYKLADLI---ERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCA 134
Query: 178 KYANELYAQQ-PIESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVV 235
+A+++ + PI+ + + R E P+ G + P+NF + PAL GNTVV
Sbjct: 135 GWADKIQGRTIPIDGNFFTYTRHE--PI-GVCGQIIPWNFPLVMLIWKIGPALSCGNTVV 191
Query: 236 WKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVF 295
KP++ L+ + ++++EAG P GVVN VPG + S + + FTGST V
Sbjct: 192 VKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVG 251
Query: 296 KQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCS 355
K + K + R+ E GGK+ ++ A++ ++V G F QGQ C
Sbjct: 252 KLIKEAAGKS-------NLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCI 304
Query: 356 ATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHGFI--GPVIHEGSFDKLA 413
A SR+++ ES +EF R + V + I G L + GP I + +DK+
Sbjct: 305 AASRIFVEESIYDEFVR---------RSVERAKKYILGNPLTPGVTQGPQIDKEQYDKIL 355
Query: 414 KVIDDAKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDA 473
+I+ K + ++ GG +KGY++QPT+ +E FGP+ + ++
Sbjct: 356 DLIESGKKE-GAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKF--K 412
Query: 474 KFEDVCELVDSTSQYGLTGSIFARD-REAIKIADEKLKYSAGNFYINDKSTGAVVAQQWF 532
+DV + ++T YGL+ +F +D +AI I+ AG ++N G V AQ F
Sbjct: 413 SLDDVIKRANNTF-YGLSAGVFTKDIDKAITISS---ALQAGTVWVN--CYGVVSAQCPF 466
Query: 533 GGARMSGTNDKAG 545
GG +MSG + G
Sbjct: 467 GGFKMSGNGRELG 479
>HsM4502031 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 158 bits (399), Expect = 2e-38
Identities = 146/493 (29%), Positives = 233/493 (46%), Gaps = 46/493 (9%)
Query: 63 LVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQA---KDKW 119
+ IN E +++ GK+ F NPA E L V + EDV A++A++QA W
Sbjct: 23 IFINNE--WHDSVSGKK--FPVFNPATEEE-LCQVEEGDKEDVDKAVKAARQAFQIGSPW 77
Query: 120 YKLPYYERASVFMKAADLICTKYRYDMLAATM--LGQGKNVYQAEIDCITELADFFRFNV 177
+ ER + K ADLI R +L ATM + GK A + + R+
Sbjct: 78 RTMDASERGRLLYKLADLI---ERDRLLLATMESMNGGKLYSNAYLSDLAGCIKTLRYCA 134
Query: 178 KYANELYAQQ-PIESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVV 235
+A+++ + PI+ + + R E P+ G + P+NF + PAL GNTVV
Sbjct: 135 GWADKIQGRTIPIDGNFFTYTRHE--PI-GVCGQIIPWNFPLVMLIWKIGPALSCGNTVV 191
Query: 236 WKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVF 295
KP++ L+ + ++++EAG P GVVN VPG + S + + FTGST V
Sbjct: 192 VKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVG 251
Query: 296 KQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCS 355
K + K + R+ E GGK+ ++ A++ ++V G F QGQ C
Sbjct: 252 KLIKEAAGKS-------NLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCI 304
Query: 356 ATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHGFI--GPVIHEGSFDKLA 413
A SR+++ ES +EF R + V + I G L + GP I + +DK+
Sbjct: 305 AASRIFVEESIYDEFVR---------RSVERAKKYILGNPLTPGVTQGPQIDKEQYDKIL 355
Query: 414 KVIDDAKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDA 473
+I+ K + ++ GG +KGY++QPT+ +E FGP+ + ++
Sbjct: 356 DLIESGKKE-GAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKF--K 412
Query: 474 KFEDVCELVDSTSQYGLTGSIFARD-REAIKIADEKLKYSAGNFYINDKSTGAVVAQQWF 532
+DV + ++T YGL+ +F +D +AI I+ AG ++N G V AQ F
Sbjct: 413 SLDDVIKRANNTF-YGLSAGVFTKDIDKAITISS---ALQAGTVWVN--CYGVVSAQCPF 466
Query: 533 GGARMSGTNDKAG 545
GG +MSG + G
Sbjct: 467 GGFKMSGNGRELG 479
>YER073w [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 152 bits (384), Expect = 1e-36
Identities = 137/493 (27%), Positives = 229/493 (45%), Gaps = 38/493 (7%)
Query: 63 LVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQA-KDKWYK 121
L INGE + ++ F +NP+N E + V +A +DV A+ A+K+A + KW
Sbjct: 46 LFINGEFVASK----QKKTFDVINPSNE-EKITTVYKAMEDDVDEAVAAAKKAFETKWSI 100
Query: 122 LPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYAN 181
+ RA ADL+ K++ + A + GK+++ A D + ++ + R +A+
Sbjct: 101 VEPEVRAKALFNLADLV-EKHQETLAAIESMDNGKSLFCARGD-VALVSKYLRSCGGWAD 158
Query: 182 ELYAQQPIESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQ 240
++Y I++ + + PL G + P+NF + + PAL GNTVV KP++
Sbjct: 159 KIYGNV-IDTGKNHFTYSIKEPL-GVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAE 216
Query: 241 NANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYG 300
LS + +EAG+P GVVN +PG+ V + + + + + FTGSTA + +
Sbjct: 217 TTPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMK 276
Query: 301 DIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRV 360
V ++ E GGK+ +++ A++ +V + G F G+ C A SR+
Sbjct: 277 VAADTV--------KKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRI 328
Query: 361 YLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAK 420
Y+ ++ EE VL +++ S + D F G + K+ +D AK
Sbjct: 329 YIQDTVYEE-------VLQKLKDYTESLKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAK 381
Query: 421 NDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCE 480
++ +V GG SKGY+++PT+ + +E FGPI+TV +KF V E
Sbjct: 382 SE-GARLVTGGARHGSKGYFVKPTVFADVKGDMRIVKEEVFGPIVTV-----SKFSTVDE 435
Query: 481 LV--DSTSQYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMS 538
++ + SQYGL I D K D + AG +IN + FGG S
Sbjct: 436 VIAMANDSQYGLAAGIHTNDIN--KAVDVSKRVKAGTVWINTYNN--FHQNVPFGGFGQS 491
Query: 539 GTNDKAGSGNILN 551
G + G + N
Sbjct: 492 GIGREMGEAALSN 504
>Hs4502041 [C] KOG2450 Aldehyde dehydrogenase
Length = 512
Score = 151 bits (381), Expect = 3e-36
Identities = 137/488 (28%), Positives = 231/488 (47%), Gaps = 36/488 (7%)
Query: 63 LVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDK---W 119
+ IN E ++ GK+ F NP+ ++ V + DV A++A++ A + W
Sbjct: 34 IFINNE--WHESKSGKK--FATCNPSTREQI-CEVEEGDKPDVDKAVEAAQVAFQRGSPW 88
Query: 120 YKLPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKY 179
+L R + + ADL+ + R + A + GK A + R+ +
Sbjct: 89 RRLDALSRGRLLHQLADLV-ERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGW 147
Query: 180 ANELYAQQPIESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKP 238
A+++ + I + V + P+ G A+TP+NF + APAL GNT+V KP
Sbjct: 148 ADKIQGKT-IPTDDNVVCFTRHEPI-GVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKP 205
Query: 239 SQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQL 298
++ L+ L ++++EAG P GVVN VPG V + S + + FTGST V K +
Sbjct: 206 AEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLV 265
Query: 299 YGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATS 358
+ + R+ E GGKN ++ A++ +V +G F QGQ C+A S
Sbjct: 266 KEAASRS-------NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAAS 318
Query: 359 RVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDD 418
RV++ E EF R ++ +PV + D+ GP I + FDK+ ++I+
Sbjct: 319 RVFVEEQVYSEFVR-RSVEYAKKRPVG------DPFDVKTEQGPQIDQKQFDKILELIES 371
Query: 419 AKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDV 478
K + ++ GG + KG +I+PT+ +E FGP+ + ++ E+V
Sbjct: 372 GKKE-GAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKF--KSIEEV 428
Query: 479 CELVDSTSQYGLTGSIFARDRE-AIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARM 537
+ +ST YGLT ++F ++ + A+K+A +G +IN A+ AQ FGG +M
Sbjct: 429 IKRANST-DYGLTAAVFTKNLDKALKLAS---ALESGTVWIN--CYNALYAQAPFGGFKM 482
Query: 538 SGTNDKAG 545
SG + G
Sbjct: 483 SGNGRELG 490
>YMR169c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 150 bits (380), Expect = 4e-36
Identities = 128/486 (26%), Positives = 225/486 (45%), Gaps = 35/486 (7%)
Query: 83 QQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKY 142
+ +NPA E + + A +DV A++A++ A D + E+ +++ + +
Sbjct: 39 ETVNPAT-GEPITSFQAANEKDVDKAVKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEE 97
Query: 143 RYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEY- 201
+ + A L GK + + ++ + R+ YA + E+ P +N+ Y
Sbjct: 98 QDTLAALETLDAGKPFHSNAKQDLAQIIELTRY---YAGAVDKFNMGETIPLTFNKFAYT 154
Query: 202 -RPLEGFVYAVTPFNFT-AIAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLP 259
+ G V + P+N+ A+A + GNTV+ KP++N +LS T++++AG P
Sbjct: 155 LKVPFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFP 214
Query: 260 NGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVG 319
GVVN +PG V K + + + + FTGST V G + + +D I
Sbjct: 215 PGVVNVIPGYGSVVGKALGTHMDIDKISFTGSTKV----GGSVLEASGQSNLKD---ITL 267
Query: 320 ETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLS 379
E GGK+ L+ A++ ++ G F GQ C+A SRVY+ S ++F
Sbjct: 268 ECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYDKFVEKFKETAK 327
Query: 380 EVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPEL------EIVFGGFH 433
+ V A K + D +GPVI +D++ I+ K + +L E GG
Sbjct: 328 KEWDV---AGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQTSEFPIGG-- 382
Query: 434 DKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGS 493
+KGY+I PTI L E FGP++ V ++ ++D +L + T YGL +
Sbjct: 383 --AKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKF--TNYDDALKLANDTC-YGLASA 437
Query: 494 IFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNILNRF 553
+F +D + + +K AG +IN T A+ FGG +MSG ++G + N +
Sbjct: 438 VFTKDVKKAHMFARDIK--AGTVWIN--QTNQEEAKVPFGGFKMSGIGRESGDTGVDN-Y 492
Query: 554 VSVRNI 559
+ ++++
Sbjct: 493 LQIKSV 498
>At1g23800 [C] KOG2450 Aldehyde dehydrogenase
Length = 508
Score = 150 bits (380), Expect = 4e-36
Identities = 142/486 (29%), Positives = 223/486 (45%), Gaps = 40/486 (8%)
Query: 82 FQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDK--WYKLPYYERASVFMKAADLIC 139
F L+P N EV+A V++ EDV A+ A+++A D+ W K+ YER+ + + ADLI
Sbjct: 45 FPTLDPRN-GEVIAQVSEGDAEDVNRAVAAARKAFDEGPWPKMTAYERSKILFRFADLI- 102
Query: 140 TKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRA 199
K+ ++ A GK Q+ + LA FR+ +A++++ P +
Sbjct: 103 EKHNDEIAALETWDNGKPYEQSAQIEVPMLARVFRYYAGWADKIHGMTMPGDGPH-HVQT 161
Query: 200 EYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNYLLLTVLEEAGL 258
+ P+ G + P+NF + + PAL GNTVV K ++ LS L+ +L EAGL
Sbjct: 162 LHEPI-GVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTPLSALLVGKLLHEAGL 220
Query: 259 PNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIV 318
P+GVVN V G + S + + FTGST V K + K + +
Sbjct: 221 PDGVVNIVSGFGATAGAAIASHMDVDKVAFTGSTDVGKIILELASKS-------NLKAVT 273
Query: 319 GETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVL 378
E GGK+ ++ A++ +V F QGQ C A SR ++ E +EF
Sbjct: 274 LELGGKSPFIVCEDADVDQAVELAHFALFFNQGQCCCAGSRTFVHERVYDEF-------- 325
Query: 379 SEVQPVNTSASKINGGDLHGF---IGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDK 435
V+ A K N GD GP + F+K+ K I + + GG
Sbjct: 326 --VEKAKARALKRNVGDPFKSGIEQGPQVDSEQFNKILKYIKHGV-EAGATLQAGGDRLG 382
Query: 436 SKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELV--DSTSQYGLTGS 493
SKGYYIQPT+ + E FGP+ T+ KF+D+ E++ + S+YGL
Sbjct: 383 SKGYYIQPTVFSDVKDDMLIATDEIFGPVQTI-----LKFKDLDEVIARANNSRYGLAAG 437
Query: 494 IFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNILNRF 553
+F ++ + L+ G +IN + A FGG +MSG + G + LN +
Sbjct: 438 VFTQNLDTAHRLMRALR--VGTVWIN--CFDVLDASIPFGGYKMSGIGREKGIYS-LNNY 492
Query: 554 VSVRNI 559
+ V+ +
Sbjct: 493 LQVKAV 498
>Hs10835045 [C] KOG2450 Aldehyde dehydrogenase
Length = 518
Score = 147 bits (370), Expect = 6e-35
Identities = 146/538 (27%), Positives = 246/538 (45%), Gaps = 57/538 (10%)
Query: 20 SHIQPPKQIGNEPVKAFGSKDLVDWDLLRASLSKFKNSSLDVPLVINGERIYYNDDGGKR 79
S I+ P ++ +P S L+ + K + IN E + N + G+
Sbjct: 4 SKIEMPGEVKADPAALMASLHLLPSPTPNLEIKYTK-------IFINNE--WQNSESGR- 53
Query: 80 GIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQA---KDKWYKLPYYERASVFMKAAD 136
+F NPA +V V +A D+ A+QA++ A W ++ ER + K AD
Sbjct: 54 -VFPVYNPATGEQV-CEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLAD 111
Query: 137 LICTKYRYDMLAATM--LGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQ-PIESSP 193
L+ R + ATM L GK QA + + FR+ +A++++ P++
Sbjct: 112 LV---ERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDY 168
Query: 194 GVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNYLLLTV 252
+ R E P+ G + P+NF + APAL GNTVV KP++ LS + +
Sbjct: 169 FTFTRHE--PI-GVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGAL 225
Query: 253 LEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYR 312
++EAG P GV+N +PG + S + FTGST V K + +
Sbjct: 226 IKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS------- 278
Query: 313 DYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFR 372
+ R+ E GGK+ ++I A++ ++V +G F QGQ C+A SR+++ ES EEF R
Sbjct: 279 NLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVR 338
Query: 373 DLGGVLSEVQPVNTSASKINGG--DLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFG 430
+ V + +I G D GP I + ++K+ ++I + ++ G
Sbjct: 339 ---------RSVERAKRRIVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAE-GAKLECG 388
Query: 431 GFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVD--STSQY 488
G KG++I+PT+ +E FGP+ + +F+ + E+++ + S +
Sbjct: 389 GKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEI-----LRFKTMDEVIERANNSDF 443
Query: 489 GLTGSIFARD-REAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAG 545
GL ++F D +A+ ++ AG +IN A+ AQ FGG +MSG + G
Sbjct: 444 GLVAAVFTNDINKALTVSS---AMQAGTVWIN--CYNALNAQSPFGGFKMSGNGREMG 496
>YMR170c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 145 bits (365), Expect = 2e-34
Identities = 125/476 (26%), Positives = 214/476 (44%), Gaps = 34/476 (7%)
Query: 83 QQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKY 142
+ +NPA E + + A +DV A++A++ A D + E+ +++ + +
Sbjct: 39 ETVNPAT-GEPITSFQAANEKDVDKAVKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEE 97
Query: 143 RYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEY- 201
+ + A L GK + + ++ R+ A++ I P +N+ Y
Sbjct: 98 QDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAGSADKFDKGATI---PLTFNKFAYT 154
Query: 202 -RPLEGFVYAVTPFNFT-AIAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLP 259
+ G V + P+N+ A+A + GNTV+ KP++N +LS T++++AG P
Sbjct: 155 LKVPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFP 214
Query: 260 NGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVG 319
GVVN VPG V + + S + + FTGST V G + + +D +
Sbjct: 215 PGVVNIVPGYGSLVGQALASHMDIDKISFTGSTKV----GGFVLEASGQSNLKD---VTL 267
Query: 320 ETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLS 379
E GGK+ L+ A++ ++ G F GQ C+A SRVY+ S ++F
Sbjct: 268 ECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCTANSRVYVQSSIYDKFVEKFKETAK 327
Query: 380 EVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPEL------EIVFGGFH 433
+ V A K + D +GPVI +D++ I+ K + +L E GG
Sbjct: 328 KEWDV---AGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKREEKLDMFQTSEFPIGG-- 382
Query: 434 DKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGS 493
+KGY+I PTI L E FGP++ V ++ ++D +L + T YGL +
Sbjct: 383 --AKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKF--TNYDDALKLANDTC-YGLASA 437
Query: 494 IFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNI 549
+F +D + + +K AG +IN + V FGG +MSG + G +
Sbjct: 438 VFTKDVKKAHMFARDIK--AGTVWINSSNDEDVTVP--FGGFKMSGIGRELGQSGV 489
>YPL061w [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 144 bits (362), Expect = 5e-34
Identities = 135/474 (28%), Positives = 222/474 (46%), Gaps = 37/474 (7%)
Query: 94 LANVTQATNEDVKAAIQASKQA--KDKWYKLPYYERASVFMKAADLICTKYRYDMLAAT- 150
+ V+ AT EDV+ AI+ + +A +W ER + K AD + + + D++++
Sbjct: 54 VCEVSSATTEDVEYAIECADRAFHDTEWATQDPRERGRLLSKLADEL--ESQIDLVSSIE 111
Query: 151 MLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEYRPLEGFVYA 210
L GK + A D +T + R YA+++ + I + G N P+ G
Sbjct: 112 ALDNGKTLALARGD-VTIAINCLRDAAAYADKVNGRT-INTGDGYMNFTTLEPI-GVCGQ 168
Query: 211 VTPFNFTAIAGNLIGAPAL-MGNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPGN 269
+ P+NF + APAL MGN + KP+ L+ ++ ++ G+P GVVN VPG
Sbjct: 169 IIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNALYFASLCKKVGIPAGVVNIVPGP 228
Query: 270 AVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLI 329
V + +D L FTGST V K + V+ + +I E GGK+ HL+
Sbjct: 229 GRTVGAALTNDPRIRKLAFTGSTEVGKSV-------AVDSSESNLKKITLELGGKSAHLV 281
Query: 330 HPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSAS 389
ANI ++ + + G F+ GQ CS+ SR+Y+ E +E L V
Sbjct: 282 FDDANIKKTLPNLVNGIFKNAGQICSSGSRIYVQEGIYDELLAAFKAYLETEIKVGNPFD 341
Query: 390 KINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYIQPTIIKTT 449
K N F G + + FD + ID K + +I+ GG KGY+I+PT+
Sbjct: 342 KAN------FQGAITNRQQFDTIMNYIDIGKKE-GAKILTGGEKVGDKGYFIRPTVFYDV 394
Query: 450 NPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVD--STSQYGLTGSIFARD-REAIKIAD 506
N + +E FGP++TV AKF+ + E V+ ++S++GL I +K+A
Sbjct: 395 NEDMRIVKEEIFGPVVTV-----AKFKTLEEGVEMANSSEFGLGSGIETESLSTGLKVA- 448
Query: 507 EKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNILNRFVSVRNIK 560
+ LK AG +IN + ++ FGG + SG + G + + + V+ ++
Sbjct: 449 KMLK--AGTVWIN--TYNDFDSRVPFGGVKQSGYGREMGE-EVYHAYTEVKAVR 497
>CE23852 [C] KOG2450 Aldehyde dehydrogenase
Length = 537
Score = 144 bits (362), Expect = 5e-34
Identities = 131/494 (26%), Positives = 228/494 (45%), Gaps = 48/494 (9%)
Query: 63 LVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQA---KDKW 119
L IN E + D F+ +NPAN ++LA V + +DV A++A+K+A +W
Sbjct: 59 LFINNEFV----DAKSGKTFEFVNPAN-GKLLAKVAEGNRDDVDIAVEAAKKAFKIGSEW 113
Query: 120 YKLPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKY 179
++ R + + ADL+ + R + + L GK +A + FR+ Y
Sbjct: 114 RRMDASHRGVLLNRLADLM-ERDRVILASLESLDNGKPYKEAYNIDLPISIKTFRYYAGY 172
Query: 180 ANELYAQQ-PIESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPAL-MGNTVVWK 237
A++ + + P+ + R E P+ G + P+NF + APAL MGNTVV K
Sbjct: 173 ADKNHGKTIPVGGDYFTYTRHE--PV-GVCGQIIPWNFPLLMQAWKLAPALAMGNTVVMK 229
Query: 238 PSQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQ 297
+ LS + ++++EA P GVVN +PG + + + S + + FTGST V K
Sbjct: 230 VAVKTPLSALHVASLIKEAQFPEGVVNIIPGRGTDAGEAIASHMDVDKVAFTGSTEVGK- 288
Query: 298 LYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSAT 357
I K + ++ E GGK+ +++ A++ +V + F QGQ CSA
Sbjct: 289 ---TIMKAAAES---NVKKVTLELGGKSPNIVFADADLEEAVRQSHHALFFNQGQCCSAG 342
Query: 358 SRVYLPESKSEEFFRDLGGVLSEV---QPVNTSASKINGGDLHGFIGPVIHEGSFDKLAK 414
SR ++ +EF ++ + P + + ++ GP I E + + K
Sbjct: 343 SRTFVEGKIYDEFVAKAKELVEKTVIGDPFDENTTQ----------GPQIDESQVETIMK 392
Query: 415 VIDDAKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAK 474
I+ K + ++V GG +GY+++PTI N + +E FGP++ V +
Sbjct: 393 YIESGKKE-GAQLVTGGVKHGDQGYFVKPTIFANVNDQMKIAQEEIFGPVMIV-----IR 446
Query: 475 FEDVCELVDSTSQ--YGLTGSIFARD-REAIKIADEKLKYSAGNFYINDKSTGAVVAQQW 531
F+ + EL++ + YGL + D +A+++A+ AG+ ++N A
Sbjct: 447 FDSMEELIEKANNTIYGLAAGVVTNDLNKALQVAN---TIRAGSVWVNCYDVFDPAAP-- 501
Query: 532 FGGARMSGTNDKAG 545
FGG + SG + G
Sbjct: 502 FGGFKQSGIGRELG 515
>SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 142 bits (359), Expect = 1e-33
Identities = 128/502 (25%), Positives = 225/502 (44%), Gaps = 40/502 (7%)
Query: 70 IYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERAS 129
+Y N + K + + EV+A V A +++ A++++K+A W K+P E+
Sbjct: 23 LYINGEWHKSAETWETVDPSIEEVIAKVYLAGEKEIDYAVKSAKEAFKTWKKVPGSEKGE 82
Query: 130 VFMKAADLICTKYRYDMLAAT-MLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQP 188
+ MK A+L T+ D LAA + GK + + R+ +A+++Y Q
Sbjct: 83 LLMKLAEL--TEKHADTLAAIEAMDSGKPLVSNARGDVDGTIALLRYCAGWADKIYGQV- 139
Query: 189 IESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNY 247
I + P A+ P+ G + P+N+ APAL GN ++ K ++ LS
Sbjct: 140 IPTGPEKLAYAKRTPI-GVCGQIVPWNYPLNMAGWKIAPALAAGNCIIIKSAETTPLSLL 198
Query: 248 LLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGST---AVFKQLYGDIQK 304
T++EEAG P GVVN + G + + FTGST + +QL K
Sbjct: 199 YFATLVEEAGFPKGVVNIISGLGTVAGSYMAKHPGIDKIAFTGSTKVGVIVQQLAASNLK 258
Query: 305 GVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPE 364
V E GGK+ L+ A++ +V G GQ C++ SR+Y+ +
Sbjct: 259 AVTL-----------ECGGKSPFLVFEDADLDQAVKWAALGIMYNSGQICTSNSRIYVQD 307
Query: 365 SKSEEFFRDLGGVLSEVQPVNTSASKING--GDLHGFIGPVIHEGSFDKLAKVIDDAKND 422
S ++F E+ + I G D + +GPV+++ ++++ I+ K +
Sbjct: 308 SVYDKFI--------ELFKKHVIQDYIVGMPFDDNTVVGPVVNKTQYNRIKNYIEQGKKE 359
Query: 423 PELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELV 482
++ +GY+I PTI + + +E FGP++ + ++ K ED
Sbjct: 360 GAKLVLGDEPLPLKQGYFISPTIFADCSENMTIVKEEIFGPVVAISKF---KTEDEAIEK 416
Query: 483 DSTSQYGLTGSIFARDRE-AIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTN 541
+ + YGL F +D E A +++DE AG +IN + A FGG +MSG
Sbjct: 417 ANNTTYGLAAMCFTKDLERAHRVSDE---LEAGMVFINSTENSDIQAP--FGGIKMSGIG 471
Query: 542 DKAGSGNILNRFVSVRNIKENY 563
++ GS N + + ++ + N+
Sbjct: 472 NELGS-NGIEMYTQIKAVHINF 492
>YOR374w [C] KOG2450 Aldehyde dehydrogenase
Length = 519
Score = 141 bits (356), Expect = 2e-33
Identities = 124/486 (25%), Positives = 236/486 (48%), Gaps = 40/486 (8%)
Query: 82 FQQLNPANHSEVLANVTQATNEDVKAAIQASKQA--KDKWYKLPYYERASVFMKAADLIC 139
F+ +NP+ E+ ++ + +DV+ A+QA+ +A W + +R + A+LI
Sbjct: 62 FEVINPSTEEEI-CHIYEGREDDVEEAVQAADRAFSNGSWNGIDPIDRGKALYRLAELI- 119
Query: 140 TKYRYDMLAAT-MLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNR 198
+ D++A+ L GK + + D + + ++ + + +A+++ + I++ ++
Sbjct: 120 -EQDKDVIASIETLDNGKAISSSRGD-VDLVINYLKSSAGFADKIDGRM-IDTGRTHFSY 176
Query: 199 AEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNYLLLTVLEEAG 257
+ +PL G + P+NF + APAL+ GNTVV K +++ LS + + +AG
Sbjct: 177 TKRQPL-GVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYIPQAG 235
Query: 258 LPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRI 317
+P GV+N V G V + + + + + FTGSTA + +Y G+ ++
Sbjct: 236 IPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGRHIYQSAAAGL--------KKV 287
Query: 318 VGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGV 377
E GGK+ +++ A + +V + + G + G+ C A SRVY+ ES ++F
Sbjct: 288 TLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVEESIYDKF------- 340
Query: 378 LSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSK 437
+ E + + S + D F G + +K+ K +D KN+ ++ GG SK
Sbjct: 341 IEEFKAASESIKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNE-GATLITGGERLGSK 399
Query: 438 GYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVD--STSQYGLTGSIF 495
GY+I+PT+ + +E FGP++TV KF+ E+++ + S+YGL I
Sbjct: 400 GYFIKPTVFGDVKEDMRIVKEEIFGPVVTV-----TKFKSADEVINMANDSEYGLAAGIH 454
Query: 496 ARD-REAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNILNRFV 554
+ A+K+AD + +AG +IN + FGG SG + S + L ++
Sbjct: 455 TSNINTALKVAD---RVNAGTVWINTYNDFHHAVP--FGGFNASGLG-REMSVDALQNYL 508
Query: 555 SVRNIK 560
V+ ++
Sbjct: 509 QVKAVR 514
>At3g48000 [C] KOG2450 Aldehyde dehydrogenase
Length = 538
Score = 140 bits (352), Expect = 7e-33
Identities = 145/525 (27%), Positives = 233/525 (43%), Gaps = 53/525 (10%)
Query: 49 ASLSKFKNSSLDVP---LVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDV 105
A+ + N S+ V L+ING + D F L+P EV+A+V + ED+
Sbjct: 43 AAAEEIINPSVQVSHTQLLINGNFV----DSASGKTFPTLDPRT-GEVIAHVAEGDAEDI 97
Query: 106 KAAIQASKQAKDK--WYKLPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEI 163
A++A++ A D+ W K+ YER+ V ++ ADL+ K+ ++ + GK Q+
Sbjct: 98 NRAVKAARTAFDEGPWPKMSAYERSRVLLRFADLV-EKHSEELASLETWDNGKPYQQSLT 156
Query: 164 DCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNL 223
I A FR+ +A++++ I + + P+ G + P+NF +
Sbjct: 157 AEIPMFARLFRYYAGWADKIHGLT-IPADGNYQVHTLHEPI-GVAGQIIPWNFPLLMFAW 214
Query: 224 IGAPALM-GNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSE 282
PAL GNT+V K ++ L+ + + EAGLP GV+N V G + S +
Sbjct: 215 KVGPALACGNTIVLKTAEQTPLTAFYAGKLFLEAGLPPGVLNIVSGFGATAGAALASHMD 274
Query: 283 FAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLST 342
L FTGST K + G + + E GGK+ ++ A+I +V
Sbjct: 275 VDKLAFTGSTDTGKVILGLAANS-------NLKPVTLELGGKSPFIVFEDADIDKAVELA 327
Query: 343 LRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGD--LHGF- 399
F QGQ C A SR ++ E +EF V+ A K GD G
Sbjct: 328 HFALFFNQGQCCCAGSRTFVHEKVYDEF----------VEKSKARALKRVVGDPFRKGIE 377
Query: 400 IGPVIHEGSFDKLAKVIDDA-KNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQ 458
GP I F+K+ K I +++ LE GG KGY+IQPT+
Sbjct: 378 QGPQIDLKQFEKVMKYIKSGIESNATLEC--GGDQIGDKGYFIQPTVFSNVKDDMLIAQD 435
Query: 459 EFFGPILTVYEYPDAKFEDVCELVD--STSQYGLTGSIFARDREAIKIADEKLKYSAGNF 516
E FGP+ ++ KF DV E++ + ++YGL +F ++ + LK AG
Sbjct: 436 EIFGPVQSI-----LKFSDVDEVIKRANETKYGLAAGVFTKNLDTANRVSRALK--AGTV 488
Query: 517 YIN--DKSTGAVVAQQWFGGARMSGTNDKAGSGNILNRFVSVRNI 559
++N D A+ FGG +MSG + G + LN ++ ++ +
Sbjct: 489 WVNCFDVFDAAIP----FGGYKMSGNGREKGIYS-LNNYLQIKAV 528
>SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 137 bits (345), Expect = 4e-32
Identities = 123/442 (27%), Positives = 206/442 (45%), Gaps = 30/442 (6%)
Query: 85 LNPANHSEVLANVTQATNEDVKAAIQASKQA--KDKWYKLPYYERASVFMKAADLICTKY 142
+NPA E++ A+ +DV +A++ + W K P +R V K A ++ K
Sbjct: 43 INPATE-EIIGTCANASAKDVDSAVENAYNTFRSGIWAKWPGKQRGLVLRKIAKMMREK- 100
Query: 143 RYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYA--NELYAQQPIESSPGVWNRAE 200
R + + GK A D I AD F + + A + + P+ ++PG + E
Sbjct: 101 RELLAGIDTINCGKPTPYALFD-IDSCADMFEYYAEVAETDNPTVKVPLPNNPG-FCAFE 158
Query: 201 YRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNYLLLTVLEEAGLP 259
R G + +TP+NF PA+ GN VV KPS+ A S + +EAGLP
Sbjct: 159 KRFPRGVIGVITPWNFPLKMALWKLVPAIASGNCVVLKPSELAPWSCLEFALICKEAGLP 218
Query: 260 NGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVG 319
+GV+N + G+ E + + A L FTGS A K++ + +V +
Sbjct: 219 DGVLNVIIGSGKESGAALSCHPKIAYLAFTGSLATGKKIMHAAAENIVP--------LTL 270
Query: 320 ETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLS 379
E GGK+ +I A++ ++ S F QG+ C+A SR+ + ES ++E LGG++S
Sbjct: 271 ELGGKSPLIICEDADLSLAIPSAAFAIFFNQGEACTAASRLIVHESVADEV---LGGLVS 327
Query: 380 EVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGY 439
E + NG D +GPV+ + F+K+ I A N+ +V G + KGY
Sbjct: 328 EANKLIIG----NGLDPQVTLGPVVSKTQFEKIVSYIQSAINEGCKCVVGGLPRSEQKGY 383
Query: 440 YIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDR 499
+I PT+ + +E FGP+L V + E+ EL + S+YGL +F+ +
Sbjct: 384 FIPPTVFTNVQTHNKIWREEIFGPVLAVKTFHTN--EEALELAND-SEYGLGSGVFSTNP 440
Query: 500 EAIKIADEKLK---YSAGNFYI 518
+ ++ ++ S N+++
Sbjct: 441 KTLEFFSNNIEAGMCSLNNYHV 462
>Hs11436533 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 137 bits (344), Expect = 6e-32
Identities = 131/483 (27%), Positives = 217/483 (44%), Gaps = 46/483 (9%)
Query: 75 DGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASK---QAKDKWYKLPYYERASVF 131
D R F +NP+ EV+ V + EDV A++A++ Q W ++ R +
Sbjct: 47 DAVSRKTFPTVNPST-GEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLL 105
Query: 132 MKAADLICTKYRYDMLAATMLGQGKNV---YQAEIDCITELADFFRFNVKYANELYAQQ- 187
+ ADLI Y + A L GK Y ++D + + R+ +A++ + +
Sbjct: 106 NRLADLIERDRTY-LAALETLDNGKPYVISYLVDLDMVLKC---LRYYAGWADKYHGKTI 161
Query: 188 PIESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSN 246
PI+ + R E P+ G + P+NF + PAL GN VV K ++ L+
Sbjct: 162 PIDGDFFSYTRHE--PV-GVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTA 218
Query: 247 YLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGV 306
+ +++EAG P GVVN VPG + S + + FTGST + + + + G
Sbjct: 219 LYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVI--QVAAGS 276
Query: 307 VNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESK 366
N R+ E GGK+ ++I A++ +V F QGQ C A SR ++ E
Sbjct: 277 SN-----LKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDI 331
Query: 367 SEEFFRDLGGVLSEVQPVNTSASKINGG--DLHGFIGPVIHEGSFDKLAKVIDDAKNDPE 424
+EF + V + S++ G D GP + E F K+ I+ K +
Sbjct: 332 YDEFVE---------RSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQE-G 381
Query: 425 LEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVD- 483
+++ GG +GY+IQPT+ +E FGP++ + KF+ + E+V
Sbjct: 382 AKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQI-----LKFKTIEEVVGR 436
Query: 484 -STSQYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTND 542
+ S YGL ++F +D + + L+ AG ++N AQ FGG +MSG+
Sbjct: 437 ANNSTYGLAAAVFTKDLDKANYLSQALQ--AGTVWVN--CYDVFGAQSPFGGYKMSGSGR 492
Query: 543 KAG 545
+ G
Sbjct: 493 ELG 495
>CE07233 [C] KOG2450 Aldehyde dehydrogenase
Length = 687
Score = 136 bits (343), Expect = 8e-32
Identities = 126/497 (25%), Positives = 225/497 (44%), Gaps = 56/497 (11%)
Query: 82 FQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTK 141
F+ + P + + +A AT + V ++ +K+A+ +W K + ER+ + K DL+ T
Sbjct: 223 FEVIEPRS-GKPMATWHYATRDQVDLTVKEAKKAQKQWAKSSWMERSEILKKTGDLLKTH 281
Query: 142 YRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQ-PIESSPGVWNRAE 200
D+ + GK + +A+ D ++ D F F A++L Q P+++S + R
Sbjct: 282 CN-DIAYWECISNGKPIAEAKADVLS-CVDTFYFYSGIASDLLGQHVPLDASRYAYTR-- 337
Query: 201 YRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNYLLLTVLEEAGLP 259
R G V A+ +N+ + APAL GN V++KPS + ++ +L +L+ AGLP
Sbjct: 338 -RLPVGVVAAIGAWNYPIQTCSWKTAPALACGNAVIYKPSPLSPVTALILAEILKSAGLP 396
Query: 260 NGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVG 319
+GV N + G+A E ++++ + + FTGS K+ I K + R+ +
Sbjct: 397 DGVFNVIQGDA-ETAQDLIHHDGVSKVSFTGSIPTGKK----IMKACAD---RNIKPVTL 448
Query: 320 ETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDL----- 374
E GGK+ ++ A+I +V + F QGQ CS S+V + +S +EF + L
Sbjct: 449 ELGGKSALIVFDDADIDSAVSCAMMANFYSQGQVCSNASKVLVHKSVLKEFTKKLVDHTQ 508
Query: 375 ----GGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSF-----DKLAKVIDDAKNDPEL 425
G L E V + S + + G+I I EG+ D++A
Sbjct: 509 KMKIGDPLKEDTQVGSHISAEHRNKVEGYISTAIAEGATKLCGGDRVA------------ 556
Query: 426 EIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDST 485
H G+Y+ P I+ P+ +E FG +L + + ED + +
Sbjct: 557 ------VHGLENGFYLSPCILTGITPKMTVYREEIFGSVLLIIPFDT---EDEAIKIAND 607
Query: 486 SQYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAG 545
+ GL + +D E+L +AGN Y+N + + + FGG SG + G
Sbjct: 608 TDMGLAAGLVTKDLSRSYRVSEQL--NAGNVYVNTYNDVSPLVP--FGGVGESGFGRENG 663
Query: 546 SGNILNRFVSVRNIKEN 562
+ +L + ++++ N
Sbjct: 664 TA-VLEHYTHLKSVFVN 679
>7297513 [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 136 bits (342), Expect = 1e-31
Identities = 134/507 (26%), Positives = 234/507 (45%), Gaps = 51/507 (10%)
Query: 65 INGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQA---KDKWYK 121
IN E ++ GK IF+ +NP +EV+A + A ED+ A+QA++ A W +
Sbjct: 44 INNE--WHKSKSGK--IFETINPTT-AEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRR 98
Query: 122 LPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQA-EIDCITELADFFRFNVKYA 180
+ ER + + ADL+ Y + + L GK + +D T + + R+ +A
Sbjct: 99 MDASERGRLLYRLADLMERDQVY-LASLETLDNGKPYSMSYNVDLPTAIKNL-RYFAGWA 156
Query: 181 NELYAQQ-PIESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKP 238
++ + + P++ + R E P+ G + P+NF + PAL GNT+V KP
Sbjct: 157 DKNHGKTIPMDGDFFTYTRHE--PV-GVCGQIIPWNFPILMMAWKLGPALATGNTIVLKP 213
Query: 239 SQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQL 298
++ +L+ + +++EAG P GVVN VPG + + + + FTGST V K +
Sbjct: 214 AEQTSLTALYIAQLVKEAGFPEGVVNVVPGFGT-AGAALANHCDVDKVAFTGSTDVGKLI 272
Query: 299 YGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATS 358
+ G N R+ E GGK+ ++I ++ ++V + G F GQ C A S
Sbjct: 273 --QLASGNTN-----LKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGS 325
Query: 359 RVYLPESKSEEFFRDLGGVLSEVQPVNTSASKI------NGGDLHGFIGPVIHEGSFDKL 412
R ++ + +EF V SA + N DL+ GP ++E +K+
Sbjct: 326 RTFVEDKIYDEF-------------VERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKI 372
Query: 413 AKVIDDAKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPD 472
+I K + G + GY++QPT+ +E FGP+ + +
Sbjct: 373 LGMIKTGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRF-- 430
Query: 473 AKFEDVCELVDSTSQYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWF 532
K ++V E ++ S+YGL ++F +D + L+ AG ++N + + AQ F
Sbjct: 431 KKLDEVIERANN-SEYGLAAAVFTKDLDKANYIVGGLR--AGTVWVN--TYNVLAAQAPF 485
Query: 533 GGARMSGTNDKAGSGNILNRFVSVRNI 559
GG +MSG + G L+ + V+++
Sbjct: 486 GGYKMSGHGRENGE-YALSNYTEVKSV 511
>At3g48170 [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 134 bits (337), Expect = 4e-31
Identities = 125/487 (25%), Positives = 225/487 (45%), Gaps = 37/487 (7%)
Query: 85 LNPANHSEVLANVTQATNEDVKAAIQASKQAKDK-----WYKLPYYERASVFMKAADLIC 139
+NPA +++ + AT+EDV+ A++A+++A + W + RA +++A
Sbjct: 28 VNPATE-DIIGYIPAATSEDVELAVEAARKAFTRNNGKDWARATGAVRAK-YLRAIAAKV 85
Query: 140 TKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQ--PIESSPGVWN 197
+ + ++ + GK + +A D + ++A F + A L A+Q P+ +
Sbjct: 86 IERKSELANLEAIDCGKPLDEAAWD-MDDVAGCFEYYADLAEGLDAKQKTPLSLPMDTFK 144
Query: 198 RAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNYLLLTVLEEA 256
+ G V +TP+N+ + AP+L G T + KPS+ A+L+ L + E
Sbjct: 145 GYILKEPIGVVGMITPWNYPLLMAVWKVAPSLAAGCTAILKPSELASLTCLELADICREV 204
Query: 257 GLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPR 316
GLP GV+N + G E + S + FTGST + K V
Sbjct: 205 GLPPGVLNILTGLGTEAGAPLASHPHVDKIVFTGSTTTGSSIMTSAAKLV--------KP 256
Query: 317 IVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGG 376
+ E GGK+ ++ +I +V T+ G F GQ CSATSR+ + E ++EF L
Sbjct: 257 VSLELGGKSPIIVFDDVDIDKAVEWTMFGCFWTNGQICSATSRLLVHERIADEF---LDK 313
Query: 377 VLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDK- 435
++ + + S G L GPV+ +G ++++ K + +A+N+ ++ GG +
Sbjct: 314 LVKWTKNIKISDPFEEGCRL----GPVVSKGQYERVLKFVSNARNE-GATVLCGGVRPEH 368
Query: 436 -SKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSI 494
KGY+++P I+ +E FGP L V + ED + + SQYGL G++
Sbjct: 369 LKKGYFVEPAIVSNVTTSMEIWREEVFGPALCVKTF---STEDEAIQLANDSQYGLAGAV 425
Query: 495 FARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNILNRFV 554
+ D E + + AG ++N + Q +GG + SG + G + N ++
Sbjct: 426 LSNDLERCDRVSK--AFQAGIVWVN--CSQPCFCQAPWGGTKRSGFGRELGEWGLEN-YL 480
Query: 555 SVRNIKE 561
SV+ + +
Sbjct: 481 SVKQVTQ 487
>7301355 [C] KOG2451 Aldehyde dehydrogenase
Length = 509
Score = 134 bits (337), Expect = 4e-31
Identities = 128/491 (26%), Positives = 234/491 (47%), Gaps = 33/491 (6%)
Query: 74 DDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKD--KWYKLPYYERASVF 131
D + F+ NPAN + V+ V T D + AI A+KQA + +W L +R+++
Sbjct: 39 DSSNAKATFEVRNPANGA-VIGKVPNMTVADAQKAIDAAKQAYESKEWRSLTAKDRSNLL 97
Query: 132 MKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIES 191
K LI ++ ++ GK + +++ + A F + + A +Y + +
Sbjct: 98 KKWHKLI-EQHSQEIAEIMTAESGKPINESKGEVAYGNA-FVEWFAEEARRIYGEIVPSA 155
Query: 192 SPGVWNRAEYRPLEGFVYAVTPFNFT-AIAGNLIGAPALMGNTVVWKPSQNANLSNYLLL 250
SP +P+ G +TP+NF A+ GA G TVV KPS++ L+ +
Sbjct: 156 SPNREIIVMKQPI-GVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVA 214
Query: 251 TVLEEAGLPNGVVNFVPGNAVEVTKEVLSDS-EFAALHFTGSTAVFKQLYGDIQKGVVNG 309
+ +AG+P GV+N V N ++ S + + FTGST V K L+ + G+
Sbjct: 215 KLAVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSADGI--- 271
Query: 310 LYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEE 369
RI E GG ++ SA+I +V + F GQ C + +R ++ +S ++
Sbjct: 272 -----KRICLELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDK 326
Query: 370 FFRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVF 429
F +G + V+ + + G D+ IGP+I+E F+K++ ++DA++ + I+
Sbjct: 327 F---VGQLKKRVEALKIGDGQ--GCDVQ--IGPLINEMQFNKVSGFVEDARSK-KANIIL 378
Query: 430 GGFHDKSKG-YYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQY 488
GG KG + PTI+ P S+E FGP++++ + D E+ + + T +
Sbjct: 379 GGQPLPDKGSLFYAPTIVTDVPPSAQLYSEEVFGPVVSIIRFRDE--EEAVKKANDTRR- 435
Query: 489 GLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGN 548
GL G ++ + + + ++L+ G +N+ A A+ FGG + SG + GS +
Sbjct: 436 GLAGYFYSENLQQVFRVAKRLE--VGMVGVNEGIISA--AEAPFGGVKESGVG-REGSKH 490
Query: 549 ILNRFVSVRNI 559
++ +V ++ I
Sbjct: 491 GIDDYVDIKYI 501
>Hs19923115 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 132 bits (332), Expect = 1e-30
Identities = 131/509 (25%), Positives = 228/509 (44%), Gaps = 42/509 (8%)
Query: 60 DVP---LVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQA- 115
D+P L IN E D + F +NP EV+ +V + DV A++A+++A
Sbjct: 33 DIPYNQLFINNEW----QDAVSKKTFPTVNPTT-GEVIGHVAEGDRADVDRAVKAAREAF 87
Query: 116 --KDKWYKLPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFF 173
W ++ ER + ADL+ + R + + L GK ++ + E+ +
Sbjct: 88 RLGSPWRRMDASERGRLLNLLADLV-ERDRVYLASLETLDNGKPFQESYALDLDEVIKVY 146
Query: 174 RFNVKYANELYAQQ-PIESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-G 231
R+ +A++ + + P++ + R E P+ G + P+NF + APAL G
Sbjct: 147 RYFAGWADKWHGKTIPMDGQHFCFTRHE--PV-GVCGQIIPWNFPLVMQGWKLAPALATG 203
Query: 232 NTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGS 291
NTVV K ++ LS L ++++EAG P GVVN + G + + + FTGS
Sbjct: 204 NTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGS 263
Query: 292 TAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQG 351
T V IQK + + R+ E GGK+ ++ A++ H+V F G
Sbjct: 264 TEVGHL----IQKAAGDS---NLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMG 316
Query: 352 QKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSASKI-NGGDLHGFIGPVIHEGSFD 410
Q C A SR ++ ES EF E K+ N +L GP + + F+
Sbjct: 317 QCCCAGSRTFVEESIYNEFL--------ERTVEKAKQRKVGNPFELDTQQGPQVDKEQFE 368
Query: 411 KLAKVIDDAKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEY 470
++ I + + +++ GG +G++I+PT+ +E FGP+ ++++
Sbjct: 369 RVLGYIQLGQKE-GAKLLCGGERFGERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKF 427
Query: 471 PDAKFEDVCELVDSTSQYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQ 530
K E+V E ++T +YGL ++F RD + + L+ AG ++N + V
Sbjct: 428 --KKIEEVVERANNT-RYGLAAAVFTRDLDKAMYFTQALQ--AGTVWVN--TYNIVTCHT 480
Query: 531 WFGGARMSGTNDKAGSGNILNRFVSVRNI 559
FGG + SG + G L + V+ +
Sbjct: 481 PFGGFKESGNGRELGEDG-LKAYTEVKTV 508
>CE10542 [C] KOG2451 Aldehyde dehydrogenase
Length = 569
Score = 132 bits (331), Expect = 2e-30
Identities = 138/514 (26%), Positives = 230/514 (43%), Gaps = 52/514 (10%)
Query: 51 LSKFKNSSLDVPLVINGERIYYNDDGGK------RGIFQQLNPANHSEVLANVTQATNED 104
LS+FK S +P G + Y GGK F LNP N+ EV+ T T +D
Sbjct: 4 LSQFKRSYSLLP---QGAQAYI---GGKWTASETGNSFDVLNPFNN-EVVDRATNCTVKD 56
Query: 105 VKAAIQASKQAKDKW-YKLPYYERASVFMKAADLICTKYRYDMLAATMLG--QGKNVYQA 161
+ A+ ++ + DKW + +R ++ K +++ + + AT+L QGK + +A
Sbjct: 57 AEKAVHSALEGFDKWAHTYSAKQRGAILHKWFEILVQR---ETELATLLTKEQGKPLAEA 113
Query: 162 EIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEYRPLE--GFVYAVTPFNF-TA 218
+ I A +F + A +Y Q + V NR E G V + P+NF TA
Sbjct: 114 RGE-IQYSAAYFDWYAGEARRVYGQVVPSA---VVNRLHLHTREPIGVVALIAPWNFPTA 169
Query: 219 IAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPG---NAVEVTK 275
+ A +G + V KPS + LS L EEAG+P GV N + N E++K
Sbjct: 170 MIARKAAAALSVGCSAVVKPSGDTPLSALALAQTAEEAGIPAGVFNVITADHSNTAEISK 229
Query: 276 EVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANI 335
+ ++ +A+ FTGST V K L V R+ E GG ++ A++
Sbjct: 230 YLCESTDVSAISFTGSTPVGKLLLAQSASTV--------KRVCLELGGNAPLIVFDDADL 281
Query: 336 PHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGD 395
+V T+ F GQ C + +R+Y+ E +++ L + E + +G +
Sbjct: 282 DVAVNGTMATKFRCSGQTCVSANRIYVHEKIHDQYISKLAAAMKEKLVLG------DGLN 335
Query: 396 LHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPY 455
GP++++ + DK ++ DA E++ GG + G +PT+I
Sbjct: 336 PKTTQGPLVNQKAVDKCELLLSDALGKGS-ELICGGKRGE-HGTSYEPTLITNVQSNTNI 393
Query: 456 LSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDREAIKIADEKLKYSAGN 515
E FGPI +V ++ D ++V E ++ + GL G +F RD+ ++ KL+ G
Sbjct: 394 AHTEIFGPIASVQKFRDE--QEVLEAANN-CRVGLAGYVFGRDQSRLQRVARKLE--VGM 448
Query: 516 FYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNI 549
+N+ A+ FGG + SG + G+ I
Sbjct: 449 VGVNEGLISC--AEAAFGGVKESGIGREGGAQGI 480
>CE29393 [C] KOG2450 Aldehyde dehydrogenase
Length = 510
Score = 131 bits (329), Expect = 3e-30
Identities = 130/475 (27%), Positives = 218/475 (45%), Gaps = 44/475 (9%)
Query: 82 FQQLNPANHSEVLANVTQATNEDVKAAIQASKQA---KDKWYKLPYYERASVFMKAADLI 138
F+ +NPAN +VLA V + DV A++A++ A +W ++ +R + + ADL+
Sbjct: 47 FETINPAN-GKVLAQVAEGDKTDVNIAVKAAQNAFRIGSEWRRMDASQRGVLLNRLADLM 105
Query: 139 CTKYRYDMLAATMLGQGKN---VYQAEIDCITELADFFRFNVKYANELYAQQ-PIESSPG 194
+ R + + L GK Y A++ + R + A++ + + PIE
Sbjct: 106 -ERDRVILASLESLDNGKPYAVAYNADLPLSIKTLRLLR---RMADKNHGKTIPIEGDYF 161
Query: 195 VWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPAL-MGNTVVWKPSQNANLSNYLLLTVL 253
+ R E P+ G + P+NF + PAL MGNTVV K ++ LS + +
Sbjct: 162 TYTRHE--PV-GVCGQIIPWNFPLLMQAWKLGPALAMGNTVVMKVAEQTPLSALHVAALT 218
Query: 254 EEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRD 313
+EAG P+GVVN +PG + + S + + FTGST V + + K +
Sbjct: 219 KEAGFPDGVVNIIPGYGHTAGQAISSHMDVDKVAFTGSTEVGRL----VMKAAAES---N 271
Query: 314 YPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRD 373
++ E GGK+ ++I A++ SV G F QGQ C A SR ++ E K + F
Sbjct: 272 VKKVTLELGGKSPNIIFADADLNDSVHQANHGLFFNQGQCCCAGSRTFV-EGKIYDDFVA 330
Query: 374 LGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFH 433
L+E + + DL GP + + + K I K D ++V GG
Sbjct: 331 RSKELAEKAVIG------DPFDLKTTQGPQVDGKQVETILKYIAAGKKD-GAQLVTGGAK 383
Query: 434 DKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQ--YGLT 491
+G++++PTI + +E FGP++T+ +F+ + ELV+ + YGL
Sbjct: 384 HGDQGHFVKPTIFANVKDQMTIAQEEIFGPVMTI-----IRFDTMEELVEKANNTIYGLA 438
Query: 492 GSIFARD-REAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAG 545
+ +D +A+ IA+ AG+ ++N A FGG + SG + G
Sbjct: 439 AGVMTKDIDKALHIANAT---RAGSVWVNCYDVFDAAAP--FGGFKQSGIGRELG 488
>Hs4502033 [C] KOG2450 Aldehyde dehydrogenase
Length = 516
Score = 130 bits (328), Expect = 4e-30
Identities = 130/483 (26%), Positives = 213/483 (43%), Gaps = 46/483 (9%)
Query: 75 DGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASK---QAKDKWYKLPYYERASVF 131
D R F +NP+ EV+ V + EDV A + Q W ++ +
Sbjct: 46 DAVSRKTFPTVNPST-GEVICQVAEGDKEDVDKAREGRPGAFQLGSPWRRMDASHSGRLL 104
Query: 132 MKAADLICTKYRYDMLAATMLGQGKNV---YQAEIDCITELADFFRFNVKYANELYAQQ- 187
+ ADLI Y + A L GK Y ++D + + R+ +A++ + +
Sbjct: 105 NRLADLIERDRTY-LAALETLDNGKPYVISYLVDLDMVLKC---LRYYAGWADKYHGKTI 160
Query: 188 PIESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSN 246
PI+ + R E P+ G + P+NF + PAL GN VV K ++ L+
Sbjct: 161 PIDGDFFSYTRHE--PV-GVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTA 217
Query: 247 YLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGV 306
+ +++EAG P GVVN VPG + S + + FTGST + + + + G
Sbjct: 218 LYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVI--QVAAGS 275
Query: 307 VNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESK 366
N R+ E GGK+ ++I A++ +V F QGQ C A SR ++ E
Sbjct: 276 SN-----LKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDI 330
Query: 367 SEEFFRDLGGVLSEVQPVNTSASKINGG--DLHGFIGPVIHEGSFDKLAKVIDDAKNDPE 424
+EF V+ V + S++ G D GP + E F K+ I+ K +
Sbjct: 331 YDEFV---------VRSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQE-G 380
Query: 425 LEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVD- 483
+++ GG +GY+IQPT+ +E FGP++ + KF+ + E+V
Sbjct: 381 AKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQI-----LKFKTIEEVVGR 435
Query: 484 -STSQYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTND 542
+ S YGL ++F +D + + L+ AG ++N AQ FGG +MSG+
Sbjct: 436 ANNSTYGLAAAVFTKDLDKANYLSQALQ--AGTVWVN--CYDVFGAQSPFGGYKMSGSGR 491
Query: 543 KAG 545
+ G
Sbjct: 492 ELG 494
>Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 975
Score = 129 bits (323), Expect = 2e-29
Identities = 128/507 (25%), Positives = 226/507 (44%), Gaps = 37/507 (7%)
Query: 65 INGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKD--KWYKL 122
ING+ + + D GK + +NP + S + V+ A+ DV A+ A+K A + +W ++
Sbjct: 447 INGQ--FTDADDGKT--YDTINPTDGSTI-CKVSYASLADVDKAVAAAKDAFENGEWGRM 501
Query: 123 PYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANE 182
ER + + ADL+ + + ++ L G A I FR+ + ++
Sbjct: 502 NARERGRLMYRLADLL-EENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDK 560
Query: 183 LYAQQ-PIESSPGVWNRA--EYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKP 238
+ PI + N + PL G + P+N+ + A L GNT+V KP
Sbjct: 561 IQGSTIPINQARPNRNLTFTKKEPL-GVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKP 619
Query: 239 SQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQL 298
+Q L+ + +AG P GV+N +PG+ + + + L FTGST + KQ+
Sbjct: 620 AQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQI 679
Query: 299 YGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATS 358
++ V+ L ++ E GGK+ +I + +V + F +G+ C A
Sbjct: 680 ---MKSCAVSNL----KKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAG 732
Query: 359 RVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDD 418
R+++ ES +EF + V+ E++ + D GP H+ +KL + +
Sbjct: 733 RLFVEESIHDEF---VTRVVEEIKKMKIGDPLDRSTD----HGPQNHKAHLEKLLQYCET 785
Query: 419 AKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDV 478
+ +V+GG + G++++PT+ +E FGPI+ + ++ + + V
Sbjct: 786 GVKE-GATLVYGGRQVQRPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGV 844
Query: 479 CELVDSTSQYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMS 538
+ +ST +YGL +F RD EKL+ AG +IN + V A FGG + S
Sbjct: 845 LQRANST-EYGLASGVFTRDINKAMYVSEKLE--AGTVFINTYNKTDVAAP--FGGVKQS 899
Query: 539 GTNDKAGSGN----ILNRFVSVRNIKE 561
G G N LNR + N+ +
Sbjct: 900 GFGKDLGIVNAFLRTLNRRIHCSNVSK 926
>At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 607
Score = 125 bits (313), Expect = 2e-28
Identities = 129/472 (27%), Positives = 203/472 (42%), Gaps = 52/472 (11%)
Query: 61 VPLVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDKWY 120
VP +I G + + +NPA EV++ V TNE+ KAA+ A+KQA W
Sbjct: 114 VPNLIGGSFV----ESQSSSFIDVINPATQ-EVVSKVPLTTNEEFKAAVSAAKQAFPLWR 168
Query: 121 KLPYYERASVFMKAADLICTKYRYDMLAATM-LGQGKNVYQAEIDCITELADFFRFNVKY 179
P R V +K +LI + D LA + QGK + + D L V++
Sbjct: 169 NTPITTRQRVMLKFQELI--RKNMDKLAMNITTEQGKTLKDSHGDIFRGLE-----VVEH 221
Query: 180 ANELYAQQPIESSPGVWNRAE---YRPLEGFVYAVTPFNFTA-IAGNLIGAPALMGNTVV 235
A + Q E P V N + R G + PFNF A I + GNT +
Sbjct: 222 ACGMATLQMGEYLPNVSNGVDTYSIREPLGVCAGICPFNFPAMIPLWMFPVAVTCGNTFI 281
Query: 236 WKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVF 295
KPS+ ++ +L + EAGLP+GV+N V G + + D + A+ F GS
Sbjct: 282 LKPSEKDPGASVILAELAMEAGLPDGVLNIVHGTN-DTVNAICDDEDIRAVSFVGSNTAG 340
Query: 296 KQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCS 355
+Y + G RI G KN L+ P ANI ++ + L F GQ+C
Sbjct: 341 MHIYA---RAAAKG-----KRIQSNMGAKNHGLVLPDANIDATLNALLAAGFGAAGQRCM 392
Query: 356 ATSR-VYLPESKSEEFFRDLGGVLSEVQPVNTSASKIN-GGDLHGFIGPVIHEGSFDKLA 413
A S V++ ++KS E + A K+ G + +GPVI + + +++
Sbjct: 393 ALSTVVFVGDAKSWE----------DKLVERAKALKVTCGSEPDADLGPVISKQAKERIC 442
Query: 414 KVIDDAKND------PELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTV 467
++I +D +IV G+ KG +I PTI+ P +E FGP+L
Sbjct: 443 RLIQSGVDDGAKLLLDGRDIVVPGY---EKGNFIGPTILSGVTPDMECYKEEIFGPVLVC 499
Query: 468 YEYPDAKFEDVCELVDSTSQYGLTGSIFARDREAIKIADEKLKYSAGNFYIN 519
+ F++ +++ ++YG +IF A + ++ AG IN
Sbjct: 500 MQ--ANSFDEAISIINK-NKYGNGAAIFTSSGAAAR--KFQMDIEAGQIGIN 546
>SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 124 bits (311), Expect = 4e-28
Identities = 127/502 (25%), Positives = 221/502 (43%), Gaps = 49/502 (9%)
Query: 61 VPLVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASK---QAKD 117
V L IN + + D G + +P+ +++ V A EDV A++ ++ Q
Sbjct: 23 VGLFINNQHV----DSVHGGRVKVYSPSTE-KLICEVADADEEDVDIAVKVARAAFQTDA 77
Query: 118 KWYKLPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNV 177
W K +R + AD I Y + + L GK++ A D + AD FR+
Sbjct: 78 PWRKFSSAQRGRCLSRLADCIEQNLEY-LASIETLDNGKSITLARGD-VQAAADCFRYYG 135
Query: 178 KYANELYAQQPIESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVW 236
+A++ Y Q IE+ + + P+ G + P+NF + APA+ GNT++
Sbjct: 136 GWADKDYGQT-IETDIKRFAYTRHEPI-GVCGQIIPWNFPFLMCAWKIAPAVACGNTIIL 193
Query: 237 KPSQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFK 296
K ++ LS L + E G P GV+N + G+ + S + + FTGST V +
Sbjct: 194 KTAELTPLSALCLTKFVPECGFPPGVINVLSGDGRRCGNAISSHMDIDKVAFTGSTGVGR 253
Query: 297 QLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSA 356
+ + + + ++ E GGK+ +++ A++ + + T G F GQ C A
Sbjct: 254 M----VMRAAASS---NLKKVTLELGGKSPNIVFNDADLDSAAVWTNYGIFYNSGQVCCA 306
Query: 357 TSRVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHG---FIGPVIHEGSFDKLA 413
SRVY+ E +EF ++ + A + GD F G + + ++++
Sbjct: 307 GSRVYVQEDVYDEF----------IKRMVAKAKTLKVGDPFAEDTFQGAQVSKQQYERIV 356
Query: 414 KVIDDA-KNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPD 472
I+ + +LEI GG + GY+++PTI+ +E FGP+L V
Sbjct: 357 SYIESGIAHGAKLEI--GGKRHGNLGYFVEPTILSNVTEDMAVGKEEIFGPVLAV----- 409
Query: 473 AKFEDVCELV--DSTSQYGLTGSIFARD-REAIKIADEKLKYSAGNFYINDKSTGAVVAQ 529
KF+ + E + + S YGL + + AIK+++ AG ++N + Q
Sbjct: 410 IKFKTIEEAIRRGNNSTYGLAAGVHTNNITNAIKVSN---ALEAGTVWVN--CYNLLHHQ 464
Query: 530 QWFGGARMSGTNDKAGSGNILN 551
FGG + SG + GS + N
Sbjct: 465 IPFGGYKESGIGRELGSYGLTN 486
>SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase
Length = 493
Score = 122 bits (307), Expect = 1e-27
Identities = 122/482 (25%), Positives = 213/482 (43%), Gaps = 32/482 (6%)
Query: 82 FQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTK 141
F+ NPA E++ V + E+ K AI A+ +A + + +R+ + + A+LI
Sbjct: 35 FEVDNPAT-GEIIGKVADVSVEETKKAISAANEAFKTYKNFTHVQRSQLLERWAELIMEN 93
Query: 142 YRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEY 201
+ D++ L GK + QAE++ +T + + ++ A + S
Sbjct: 94 -KDDLVKMLTLENGKPLSQAEME-VTTCSGYLKWYAAEAVRTFGDVAPSSLQSQNFLISI 151
Query: 202 RPLEGFVYAVTPFNF-TAIAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLPN 260
+ G +TP+NF A+ GA G T ++ P+ L+ + +EAG P+
Sbjct: 152 KQPVGVSALITPWNFPAAMIARKGGAALAAGCTAIFLPAFRTPYVCLGLVRLAQEAGFPD 211
Query: 261 GVVNFVPGNAVEVT-KEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVG 319
GV+N + + KE+ ++ + FTGST V K L G + ++
Sbjct: 212 GVLNVITSSDASAHGKELTTNPIVRKVSFTGSTNVGKILMGQSASTI--------KKVSM 263
Query: 320 ETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLS 379
E GG ++ P I +V S F GQ C +RVY+ ++ +EF L
Sbjct: 264 ELGGNAPFIVFPDFPIDQAVESFCTIKFNSCGQVCVCPNRVYVHKNVYDEFVSKL---TE 320
Query: 380 EVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGY 439
+V+ + +G D +GP+I + K++K I+DA + V G SKGY
Sbjct: 321 KVKTIKVG----DGFDSSSAVGPLISQDGCKKVSKHIEDAVSKGAKITVGGKEISSSKGY 376
Query: 440 YIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDR 499
+ +PT++ S+E FGP+ +V+++ D E+V E + S GL G +F +
Sbjct: 377 FFEPTVLSGVTQDMLVASEETFGPLASVFKFDDT--EEVIEWAND-SDVGLAGYVFTNNL 433
Query: 500 EA-IKIADE-KLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNILNRFVSVR 557
I +A E ++ N + D+ + FGG + SG +AG + F+ V+
Sbjct: 434 STMIHVAKELEVGLVGANIEMVDEPFIS------FGGIKQSGFGKEAGRLGV-QEFMVVK 486
Query: 558 NI 559
I
Sbjct: 487 EI 488
>CE06980 [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 122 bits (307), Expect = 1e-27
Identities = 127/509 (24%), Positives = 225/509 (43%), Gaps = 60/509 (11%)
Query: 73 NDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFM 132
N+ + +NP+ + + T +V A++A+K+A W K +R+++
Sbjct: 34 NEFARSEKLMDSVNPSTGKPWI-KIPDGTAREVDQAVEAAKEAFKTWKKTTVQQRSALLN 92
Query: 133 KAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYAN----ELYAQQP 188
K A+LI ++ D+ QGK + A++ I FR +AN L
Sbjct: 93 KVANLI-EEFNDDIAILESRDQGKPIGLAKVMDIPRCVQNFR---DFANAALYSLSTSTI 148
Query: 189 IESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNY 247
+E G + G ++P+N + APAL+ GNTVV KPS+ +++ +
Sbjct: 149 LEQPTGKFVNYVKNDPVGVAGLISPWNLPLYLLSFKLAPALVAGNTVVCKPSEMTSVTAW 208
Query: 248 LLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVV 307
+L+ + G P GVVN V G + ++ + + FTGST + K++ D K +
Sbjct: 209 VLMHAFKLVGFPPGVVNMVIGEGKSAGQRLVDHVDVPLISFTGSTVIGKKIQEDGAK--L 266
Query: 308 NGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKS 367
N ++ E GGKN +++ + + S R +F QG+ C TSR+++ +
Sbjct: 267 N------KKVSLEMGGKNPGIVYSNYR-KSDIASIARSSFLNQGEICLCTSRLFVQKPIF 319
Query: 368 EEFFRDLGGVLSEVQPVNTSASKINGGD--LHGFIGPVIHEGSFDKLAKVIDDAKNDPEL 425
+F V+ A K GD IG + + ++K+ I+ AK +
Sbjct: 320 ADF----------VKSYVEEAKKFTVGDPTTQVQIGAMNSKVHYEKVKSYIELAKKE-GA 368
Query: 426 EIVFGGF----HDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCEL 481
+I+ GG + GY+I PT+I + ++ E FGP++ + + A E+V E
Sbjct: 369 DILCGGVTTIQNGCENGYFITPTVIVGLHDASKVMTDEIFGPVVCITPFDTA--EEVIER 426
Query: 482 VDSTSQYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQW--------FG 533
+ST YGL+ ++++ D +DE L + N+ G V W FG
Sbjct: 427 ANST-PYGLSATVWSSD------SDELLNTA------NELRAGTVWCNTWLARDLSMPFG 473
Query: 534 GARMSGTNDKAGSGNILNRFVSVRNIKEN 562
G + SG N + G + L+ + + + N
Sbjct: 474 GCKQSG-NGREGLHDSLHFYSDAKTVCVN 501
>Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 121 bits (303), Expect = 3e-27
Identities = 125/507 (24%), Positives = 222/507 (43%), Gaps = 34/507 (6%)
Query: 63 LVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKD--KWY 120
L I GE + + +G K + +NP + S V+ V+ A DV A+ A+K A + +W
Sbjct: 424 LFIGGE--FVDAEGAKTS--ETINPTDGS-VICQVSLAQVTDVDKAVAAAKDAFENGRWG 478
Query: 121 KLPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYA 180
K+ +R + + ADL+ +++ ++ L G A + FR+ +
Sbjct: 479 KISARDRGRLMYRLADLM-EQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWC 537
Query: 181 NELYAQQ-PIESSPGVWNRAEYRPLE-GFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWK 237
+++ PI + N R G + P+N+ + + A L GNTVV K
Sbjct: 538 DKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIK 597
Query: 238 PSQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQ 297
P+Q L+ + +AG+P GVVN +PG+ V + + + + FTGST V K
Sbjct: 598 PAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKH 657
Query: 298 LYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSAT 357
+ + + + ++ E GGK+ +I ++ +V + F +G+ C A
Sbjct: 658 I-------MKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAA 710
Query: 358 SRVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVID 417
R+++ +S +EF R V+ EV+ + N D GP H KL +
Sbjct: 711 GRLFVEDSIHDEFVR---RVVEEVRKMKVG----NPLDRDTDHGPQNHHAHLVKLMEYCQ 763
Query: 418 DAKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFED 477
+ +V GG G++ +PT+ +E FGP++ + + D +
Sbjct: 764 HGVKE-GATLVCGGNQVPRPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDA 822
Query: 478 VCELVDSTSQYGLTGSIFARD-REAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGAR 536
V ++T ++GL +F RD +A+ ++D K AG ++N + V A FGG +
Sbjct: 823 VLSRANAT-EFGLASGVFTRDINKALYVSD---KLQAGTVFVNTYNKTDVAAP--FGGFK 876
Query: 537 MSGTNDKAGSGNILNRFVSVRNIKENY 563
SG G LN ++ V+ + Y
Sbjct: 877 QSGFGKDLGEA-ALNEYLRVKTVTFEY 902
>At1g79440 [C] KOG2451 Aldehyde dehydrogenase
Length = 528
Score = 121 bits (303), Expect = 3e-27
Identities = 124/482 (25%), Positives = 212/482 (43%), Gaps = 43/482 (8%)
Query: 86 NPANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKYRYD 145
NPA E++A+V ++ AI +S +A W +L ER+ V + DL+ ++ +
Sbjct: 74 NPAT-GEIIADVACMGTKETNDAIASSYEAFTSWSRLTAGERSKVLRRWYDLLIA-HKEE 131
Query: 146 MLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRA--EYRP 203
+ L QGK + +A I + A F + + A +Y P + +R +
Sbjct: 132 LGQLITLEQGKPLKEA-IGEVAYGASFIEYYAEEAKRVYGDI---IPPNLSDRRLLVLKQ 187
Query: 204 LEGFVYAVTPFNFT-AIAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLPNGV 262
G V A+TP+NF A+ +G G TVV KPS+ L+ + +AG+P G
Sbjct: 188 PVGVVGAITPWNFPLAMITRKVGPALASGCTVVVKPSELTPLTALAAAELALQAGVPPGA 247
Query: 263 VNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETG 322
+N V GNA E+ +L+ + + FTGSTAV K+L V ++ E G
Sbjct: 248 LNVVMGNAPEIGDALLTSPQVRKITFTGSTAVGKKLMAAAAPTV--------KKVSLELG 299
Query: 323 GKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQ 382
G ++ A++ +V TL F GQ C +RV + + ++F +
Sbjct: 300 GNAPSIVFDDADLDVAVKGTLAAKFRNSGQTCVCANRVLVQDGIYDKF----------AE 349
Query: 383 PVNTSASKINGGDLHGF-----IGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSK 437
+ + K+ GD GF GP+I++ + K+ + DA + I+ G H
Sbjct: 350 AFSEAVQKLEVGD--GFRDGTTQGPLINDAAVQKVETFVQDAVSKGAKIIIGGKRHSLGM 407
Query: 438 GYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFAR 497
+Y +PT+I+ + +E FGP+ + + ED + + T GL IF
Sbjct: 408 TFY-EPTVIRDVSDNMIMSKEEIFGPVAPLIRFKTE--EDAIRIANDTIA-GLAAYIFTN 463
Query: 498 DREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNILNRFVSVR 557
+ E L+Y G +N+ VA FGG + SG + GS ++ ++ ++
Sbjct: 464 SVQRSWRVFEALEY--GLVGVNEGLISTEVAP--FGGVKQSGLG-REGSKYGMDEYLEIK 518
Query: 558 NI 559
+
Sbjct: 519 YV 520
>HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 120 bits (300), Expect = 7e-27
Identities = 124/507 (24%), Positives = 222/507 (43%), Gaps = 34/507 (6%)
Query: 63 LVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKD--KWY 120
L I GE + + +G K + +NP + S V+ V+ A DV A+ A+K A + +W
Sbjct: 424 LFIGGE--FVDAEGAKTS--ETINPTDGS-VICQVSLAQVTDVDKAVAAAKGAFENGRWG 478
Query: 121 KLPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYA 180
K+ +R + + ADL+ +++ ++ L G A + FR+ +
Sbjct: 479 KISARDRGRLMYRLADLM-EQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWC 537
Query: 181 NELYAQQ-PIESSPGVWNRAEYRPLE-GFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWK 237
+++ PI + N R G + P+N+ + + A L GNTVV K
Sbjct: 538 DKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIK 597
Query: 238 PSQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQ 297
P+Q L+ + +AG+P GVVN +PG+ V + + + + FTGST V K
Sbjct: 598 PAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKH 657
Query: 298 LYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSAT 357
+ + + + ++ E GG++ +I ++ +V + F +G+ C A
Sbjct: 658 I-------MKSCAISNVKKVSLELGGESPFIIFADCDLNKAVQMGMSSVFFSKGENCIAA 710
Query: 358 SRVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVID 417
R+++ +S +EF R V+ EV+ + N D GP H KL +
Sbjct: 711 GRLFVEDSIHDEFVR---RVVEEVRKMKVG----NPLDRDTDHGPQNHHAHLVKLMEYCQ 763
Query: 418 DAKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFED 477
+ +V GG G++ +PT+ +E FGP++ + + D +
Sbjct: 764 HGVKE-GATLVCGGNQVPRPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDA 822
Query: 478 VCELVDSTSQYGLTGSIFARD-REAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGAR 536
V ++T ++GL +F RD +A+ ++D K AG ++N + V A FGG +
Sbjct: 823 VLSRANAT-EFGLASGVFTRDINKALYVSD---KLQAGTVFVNTYNKTDVAAP--FGGFK 876
Query: 537 MSGTNDKAGSGNILNRFVSVRNIKENY 563
SG G LN ++ V+ + Y
Sbjct: 877 QSGFGKDLGEA-ALNEYLRVKTVTFEY 902
>Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 535
Score = 117 bits (294), Expect = 4e-26
Identities = 118/455 (25%), Positives = 202/455 (43%), Gaps = 42/455 (9%)
Query: 50 SLSKFKNSSLDVPLVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAI 109
S S F +S V L I G+ + D NPA + EV+ V QAT ++ AAI
Sbjct: 29 SASSFSSSVPTVKLFIGGKFVESKSDKW----IDIHNPATN-EVIGRVPQATKAEMDAAI 83
Query: 110 QASKQAKDKWYKLPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITEL 169
+ K+A W R V ++ LI + ++ L QGK + AE D L
Sbjct: 84 ASCKRAFPAWADTSVLSRQQVLLRYQQLIKENLK-EIAKLITLEQGKTLADAEGDVFRGL 142
Query: 170 ADFFRFNVKYANELYAQQPIESSPGVWNRAE---YRPLEGFVYAVTPFNFTAIAGNLIGA 226
V++A + + E+ P + + YR G + PFNF A+ +
Sbjct: 143 QV-----VEHACSVTSLMMGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFP 197
Query: 227 PALM-GNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAA 285
A++ GNT + KPS+ + LL +L+++G P+G +N + G E + + A
Sbjct: 198 MAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNIIHGQH-EAVNFICDHPDIKA 256
Query: 286 LHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRG 345
+ F GS + ++ ++G +G R+ G KN ++ P AN +++ +
Sbjct: 257 ISFVGSNKAGEYIF---ERGSRHG-----KRVQANMGAKNHGVVMPDANKENTLNQLVGA 308
Query: 346 AFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHGF-IGPVI 404
AF GQ+C A S L +++++ +L + ++N GD G +GP+I
Sbjct: 309 AFGAAGQRCMALSTAVL-VGEAKKWLPEL--------VEHAKNLRVNAGDQPGADLGPLI 359
Query: 405 HEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGY----YIQPTIIKTTNPRHPYLSQEF 460
+ +++ +ID + I+ G K KGY ++ PTII P +E
Sbjct: 360 TPQAKERVCNLIDSGTKE-GASILLDGRKIKVKGYENGNFVGPTIISNVKPNMTCYKEEI 418
Query: 461 FGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIF 495
FGP+L V E ++ ++V++ + YG +IF
Sbjct: 419 FGPVLVVLE--TETLDEAIQIVNN-NPYGNGTAIF 450
>7301524 [C] KOG2450 Aldehyde dehydrogenase
Length = 659
Score = 116 bits (290), Expect = 1e-25
Identities = 119/496 (23%), Positives = 214/496 (42%), Gaps = 42/496 (8%)
Query: 63 LVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQA---KDKW 119
L IN E + + GK F NPA E++ V++ D+ A++A+K+A +W
Sbjct: 187 LFINNE--FVDSVSGKT--FATFNPATSKEIV-QVSEGDKADIDLAVKAAKKAFHRDSEW 241
Query: 120 YKLPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKY 179
KL +R ++ K L+ + + + GK +A D +T ++ +
Sbjct: 242 RKLSPLQRTNLMNKLCALMDRDKAF-LASLETQDNGKPYAEALFD-VTYSILTLQYYAGW 299
Query: 180 ANELYAQQPIESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPAL-MGNTVVWKP 238
++ + + G + P+ G V + P+N+ + PAL +G T++ KP
Sbjct: 300 TDKFFGDTI--PAGGFVSMTRKEPV-GVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKP 356
Query: 239 SQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQL 298
++ L+ + + +EAG P GV+N V G + + + A + FTGS + + +
Sbjct: 357 AEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIV 416
Query: 299 YGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATS 358
+Q + L R+ E GGK+ ++ A+I +V +T F GQ C A S
Sbjct: 417 ---MQAAATSNL----KRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGS 469
Query: 359 RVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDD 418
R Y+ E +EF + N + GP I + K+ I+
Sbjct: 470 RTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQ-------GPQIDDDMLTKVLGYIES 522
Query: 419 AKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDV 478
K + ++ GG + G++++PT+ +E FGP+ +++ KF +
Sbjct: 523 GKKE-GAKLQAGGKRIGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIF-----KFSSL 576
Query: 479 CELVDSTS--QYGLTGSIFARD-REAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGA 535
E++D + QYGL + D +A+K A+ AG+ +IN AV+ FGG
Sbjct: 577 EEMIDRANNVQYGLAAGVITNDINKALKFAN---NVDAGSVWIN--CYDAVLPSTPFGGY 631
Query: 536 RMSGTNDKAGSGNILN 551
+ SG + G + N
Sbjct: 632 KHSGIGRELGKDGLDN 647
>At1g74920 [C] KOG2450 Aldehyde dehydrogenase
Length = 481
Score = 115 bits (287), Expect = 2e-25
Identities = 130/489 (26%), Positives = 212/489 (42%), Gaps = 65/489 (13%)
Query: 85 LNPANHSEV-----LANVTQATNEDVKAAIQASKQAKDK-----WYKLPYYERASVFMKA 134
+NPA ++ + ++ AT EDV A+ A+++A + W K P RA +++A
Sbjct: 28 VNPATEEDLYVLDEIGDIPAATTEDVDVAVNAARRALSRNKGKDWAKAPGAVRAK-YLRA 86
Query: 135 ADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPG 194
+ + D+ L GK + +A D + ++A F F A L A+Q S
Sbjct: 87 IAAKVNERKTDLAKLEALDCGKPLDEAVWD-MDDVAGCFEFYADLAEGLDAKQKAPVSLP 145
Query: 195 VWNRAEY---RPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNYLLL 250
+ + Y +PL G V +TP+N+ + AP+L G T + KPS+ A+++ L
Sbjct: 146 MESFKSYVLKQPL-GVVGLITPWNYPLLMAVWKVAPSLAAGCTAILKPSELASVTCLELA 204
Query: 251 TVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGL 310
+ E GLP GV+N + G E + S + FTGS A + V+
Sbjct: 205 DICREVGLPPGVLNVLTGFGSEAGAPLASHPGVDKIAFTGSFATGSK--------VMTAA 256
Query: 311 YRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEF 370
+ + E GGK+ ++ ++ + L G F GQ CSATSR+ + ES + EF
Sbjct: 257 AQLVKPVSMELGGKSPLIVFDDVDLDKAAEWALFGCFWTNGQICSATSRLLVHESIASEF 316
Query: 371 FRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFG 430
L + + + S G L GPV+ +G LE
Sbjct: 317 IEKL---VKWSKNIKISDPMEEGCRL----GPVVSKGQ---------------HLE---- 350
Query: 431 GFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGL 490
KG++I+PTII +E FGP+L V + A ++ EL + S YGL
Sbjct: 351 ------KGFFIEPTIITDVTTSMQIWREEVFGPVLCVKTF--ASEDEAIELAND-SHYGL 401
Query: 491 TGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNIL 550
++ + D E E + AG +IN + Q +GG + SG + G L
Sbjct: 402 GAAVISNDTERCDRISE--AFEAGIVWIN--CSQPCFTQAPWGGVKRSGFGRELGEWG-L 456
Query: 551 NRFVSVRNI 559
+ ++SV+ +
Sbjct: 457 DNYLSVKQV 465
>Hs4502047 [C] KOG2450 Aldehyde dehydrogenase
Length = 493
Score = 114 bits (284), Expect = 5e-25
Identities = 118/481 (24%), Positives = 213/481 (43%), Gaps = 44/481 (9%)
Query: 76 GGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAA 135
GG+ G + PA V+A T + ++V A+Q +K A W + ER + ++AA
Sbjct: 22 GGRSGTEKAFEPAT-GRVIATFTCSGEKEVNLAVQNAKAAFKIWSQKSGMERCRILLEAA 80
Query: 136 DLICTKYRYDMLAAT-MLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQ---QPIES 191
+I + R D +A + GK++++A +D D ++Y L A + I+
Sbjct: 81 RII--REREDEIATMECINNGKSIFEARLDI-----DISWQCLEYYAGLAASMAGEHIQL 133
Query: 192 SPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNYLLL 250
G + PL G + +N+ + APAL GN +V+KPS +S LL
Sbjct: 134 PGGSFGYTRREPL-GVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLA 192
Query: 251 TVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGL 310
+ EAG+P G+ N V G A + + + A + FTGS ++ KG+
Sbjct: 193 EIYSEAGVPPGLFNVVQGGAA-TGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGI---- 247
Query: 311 YRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEF 370
+ E GGK+ +I ++ ++V L F QGQ C +RV++ + ++F
Sbjct: 248 ----KPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKF 303
Query: 371 FRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFG 430
+ V+ + Q + + + GP+I+ +++ + AK + G
Sbjct: 304 TEE---VVKQTQRIKIGDPLLEDTRM----GPLINRPHLERVLGFVKVAKEQGAKVLCGG 356
Query: 431 GFH-----DKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDST 485
+ GYY++P ++ + +E FGP++++ + D + E + D+T
Sbjct: 357 DIYVPEDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSF-DTEAEVLERANDTT 415
Query: 486 SQYGLTGSIFARD-REAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKA 544
+GL +F RD + A ++ E AG +IN+ + V + FGG + SG +
Sbjct: 416 --FGLAAGVFTRDIQRAHRVVAE---LQAGTCFINNYNVSPV--ELPFGGYKKSGFGREN 468
Query: 545 G 545
G
Sbjct: 469 G 469
>Hs4507229 [C] KOG2451 Aldehyde dehydrogenase
Length = 535
Score = 113 bits (283), Expect = 7e-25
Identities = 116/484 (23%), Positives = 216/484 (43%), Gaps = 35/484 (7%)
Query: 82 FQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTK 141
F +PA+ + L V + +AA++A+ +A +W ++ ER+S+ K +L+
Sbjct: 76 FPVQDPASGA-ALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQN 134
Query: 142 YRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEY 201
+ D+ GK + +A + + A F + + A +Y I +P RA
Sbjct: 135 -KDDLARIITAESGKPLKEAHGEILYS-AFFLEWFSEEARRVYGD--IIHTPAKDRRALV 190
Query: 202 --RPLEGFVYAVTPFNF-TAIAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGL 258
+P+ G +TP+NF +A+ +GA G TVV KP+++ S L + +AG+
Sbjct: 191 LKQPI-GVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGI 249
Query: 259 PNGVVNFVP---GNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYP 315
P+GV N +P NA EV + + +D + + FTGST K L V
Sbjct: 250 PSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSV--------K 301
Query: 316 RIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLG 375
R+ E GG ++ SAN+ +V + F GQ C +++ + + F +
Sbjct: 302 RVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFA 361
Query: 376 GVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDK 435
+ + V NG + GP+I+E + +K+ K ++DA + + G H
Sbjct: 362 EAMKKNLRVG------NGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQL 415
Query: 436 SKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIF 495
K ++ +PT++ +E FGP+ V ++ E+ + + + GL G +
Sbjct: 416 GKNFF-EPTLLCNVTQDMLCTHEETFGPLAPVIKFDT---EEEAIAIANAADVGLAGYFY 471
Query: 496 ARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNILNRFVS 555
++D I E+L+ G +N+ +V FGG + SG + GS ++ ++
Sbjct: 472 SQDPAQIWRVAEQLE--VGMVGVNEGLISSVECP--FGGVKQSGLG-REGSKYGIDEYLE 526
Query: 556 VRNI 559
++ +
Sbjct: 527 LKYV 530
>Hs12007648 [C] KOG2450 Aldehyde dehydrogenase
Length = 487
Score = 113 bits (282), Expect = 9e-25
Identities = 115/484 (23%), Positives = 210/484 (42%), Gaps = 50/484 (10%)
Query: 92 EVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKYRYDMLAATM 151
EV V + ++++AA++A+++A W ER+ V + ADL+ + A
Sbjct: 34 EVYCRVPNSGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLE-EFAQAES 92
Query: 152 LGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEYRPLEGFVYAV 211
QGK + A I FRF + ++ G + P+ G +
Sbjct: 93 KDQGKTLALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMHYTVRAPV-GVAGLI 151
Query: 212 TPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPGNA 270
+P+N APA+ GNTV+ KPS+ +++ ++L +L++AG+P GVVN V G
Sbjct: 152 SPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTG 211
Query: 271 VEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIH 330
V + ++S E + FTGS ++ + ++ E GGKN +I
Sbjct: 212 PRVGEALVSHPEVPLISFTGSQPTAER--------ITQLSAPHCKKLSLELGGKNPAIIF 263
Query: 331 PSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSASK 390
AN+ + +T+R +F QG+ C TSR+++ +S EF + + + S
Sbjct: 264 EDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFLKRFVEATRKWKVGIPSDPL 323
Query: 391 INGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDK-------SKGYYIQP 443
++ IG +I + +K+ + A + +I G DK GY++ P
Sbjct: 324 VS-------IGALISKAHLEKVRSYVKRALAE-GAQIWCGEGVDKLSLPARNQAGYFMLP 375
Query: 444 TIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDREAIK 503
T+I +++E FGP+ V + E+V E ++ +YGL ++++ + +
Sbjct: 376 TVITDIKDESCCMTEEIFGPVTCVVPFDSE--EEVIERANNV-KYGLAATVWSSNVGRVH 432
Query: 504 IADEKLKYSAGNFYINDKSTGAVVAQQW--------FGGARMSGTNDKAGSGNILNRFVS 555
+KL+ +G V W FGG + SG + G+ + + F
Sbjct: 433 RVAKKLQ------------SGLVWTNCWLIRELNLPFGGMKSSGIG-REGAKDSYDFFTE 479
Query: 556 VRNI 559
++ I
Sbjct: 480 IKTI 483
>At1g54100 [C] KOG2453 Aldehyde dehydrogenase
Length = 508
Score = 110 bits (275), Expect = 6e-24
Identities = 123/467 (26%), Positives = 207/467 (43%), Gaps = 31/467 (6%)
Query: 85 LNPANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKYRY 144
LNPAN+ + A V +A+ ED + ++A ++A W ++ +R + + D + +K Y
Sbjct: 39 LNPANNQPI-AQVVEASLEDYEQGLKACEEAAKIWMQVTAPKRGDIVRQIGDALRSKLDY 97
Query: 145 DMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEYRPL 204
+ L GK + + I + E+ D F V + +L P + PL
Sbjct: 98 -LGRLLSLEMGKILAEG-IGEVQEVIDMCDFAVGLSRQLNGSVIPSERPNHMMLEMWNPL 155
Query: 205 EGFVYAVTPFNFT-AIAGNLIGAPALMGNTVVWKPSQNANLSNY----LLLTVLEEAGLP 259
G V +T FNF A+ G + GN VVWK + L L+ VLE+ LP
Sbjct: 156 -GIVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAMTKLVAEVLEKNNLP 214
Query: 260 NGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVG 319
+ + G A E+ + + D+ + FTGS+ V G + + VN + +
Sbjct: 215 GAIFTAMCGGA-EIGEAIAKDTRIPLVSFTGSSRV-----GSMVQQTVNARSG---KTLL 265
Query: 320 ETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLS 379
E G N ++ A+I + S L A GQ+C+ R+ L ES ++ L
Sbjct: 266 ELSGNNAIIVMDDADIQLAARSVLFAAVGTAGQRCTTCRRLLLHESVYDKVLEQLLTSYK 325
Query: 380 EVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGY 439
+V+ N + G L G + + +F+K +VI +I+ GG + +G
Sbjct: 326 QVKIGN----PLEKGTLLGPLHTPESKKNFEKGIEVIKSQGG----KILTGGKAVEGEGN 377
Query: 440 YIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDR 499
+++PTII+ + + +E F P+L V ++ F + + +S Q GL+ SIF R+
Sbjct: 378 FVEPTIIEISADA-AVVKEELFAPVLYVLKF--KSFGEAVAINNSVPQ-GLSSSIFTRNP 433
Query: 500 EAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGS 546
E I L G +N + GA + FGG + +G +AGS
Sbjct: 434 ENIFRWIGPLGSDCGIVNVNIPTNGAEIGGA-FGGEKATGGGREAGS 479
>CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 523
Score = 110 bits (274), Expect = 8e-24
Identities = 122/461 (26%), Positives = 206/461 (44%), Gaps = 46/461 (9%)
Query: 46 LLRASLSKFKNSSLDVPLVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDV 105
L S SK ++ V L I+G+ + + + NPA + EV+A V AT ++
Sbjct: 15 LAHFSTSKSAAAAPTVKLWIDGQAV----ESKTTDFVELTNPATN-EVIAMVPNATQAEM 69
Query: 106 KAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDC 165
+AA+ ++K A + W R K LI + + + + QGK + AE D
Sbjct: 70 QAAVDSAKNAFNTWKNTSPLTRQQCMFKLQALIKRDMK-KLAESITIEQGKTLPDAEGDV 128
Query: 166 ITELADFFRFNVKYANELYAQQPIESSPGV---WNRAEYRPLEGFVYAVTPFNFTAIAGN 222
L V++A + + E+ P V + YR G + PFNF A+
Sbjct: 129 SRGLQV-----VEHACSVPSLMMGETLPNVSRDMDTHSYRIPLGVTAGICPFNFPAMIPL 183
Query: 223 LIGAPALM-GNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDS 281
+ AL GNT+V KPS+ + LL+ + +EAG+P+G VN + G V + +
Sbjct: 184 WMFPVALATGNTMVIKPSEQDPGAAQLLVELAKEAGVPDGCVNIIHGQHSAV-NFICDNP 242
Query: 282 EFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLS 341
+ A+ F G A K +Y ++G NG R+ G KN +I AN ++
Sbjct: 243 DIKAISFVGGDAAGKHIY---ERGAKNG-----KRVQSNMGAKNHGVIMADANKEQTLNQ 294
Query: 342 TLRGAFEFQGQKCSA-TSRVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHGFI 400
AF GQ+C A T+ V + E+++ L ++ + + + +A D I
Sbjct: 295 LTAAAFGAAGQRCMALTTAVLVGEARAW-----LPELVEKAKNLKVNAGWKPDTD----I 345
Query: 401 GPVIHEGSFDKLAKVIDDAKND------PELEIVFGGFHDKSKGYYIQPTIIKTTNPRHP 454
GP+I + S ++ ++I+ AK + I GF + G ++ PTI+ P
Sbjct: 346 GPLISKQSKARVLRLIESAKKEGAQVPLDGSNITVPGFEN---GNFVGPTILAGVKPNMT 402
Query: 455 YLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIF 495
+E FGP+L V E + + E++++ + YG +IF
Sbjct: 403 CYREEIFGPVLVVMEAEN--LNEAIEIINN-NPYGNGTAIF 440
>CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 887
Score = 107 bits (267), Expect = 5e-23
Identities = 115/491 (23%), Positives = 213/491 (42%), Gaps = 57/491 (11%)
Query: 82 FQQLNPANHSEVLANVTQATNEDVKAAIQASKQA--KDKWYKLPYYERASVFMKAADLIC 139
F+ +NPA + + AT DV A++A+K+A + +W ++ ER K A+L+
Sbjct: 445 FKTINPATEKPI-CELPLATVADVDRAVRAAKKAFERGEWRQMSARERGKRLYKLAELM- 502
Query: 140 TKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQ-PIESSPGVWNR 198
+++ ++ L G A + D +R+ + +++ + PI ++ N
Sbjct: 503 EEHKEELATLESLDAGAVYTLALKTHVGMSIDVWRYFAGWCDKIQGKTIPISNARPNKNL 562
Query: 199 A-EYRPLEGFVYAVTPFNFTAIAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAG 257
R G V +TP+N+ P +M + WK + + L+ +
Sbjct: 563 CLTLREPIGVVGLITPWNY----------PLMM---LSWKMAACLAAAKIKLIEI----- 604
Query: 258 LPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRI 317
+GV+N V G+ V + + + + FTGST + + K + ++
Sbjct: 605 --SGVINIVTGSGSLVGNRLTAHPDVRKIGFTGSTEIGATVMESCAKSNIK-------KV 655
Query: 318 VGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGV 377
E GGK+ +I A++ +V F +G+ C A RV++ +S ++F + L
Sbjct: 656 SLELGGKSPLIIFADADLEKAVKQACGAVFFNKGENCIAAGRVFIAKSIHDDFVKKLVEE 715
Query: 378 LSEVQ---PVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDA-KNDPELEIVFGGFH 433
+ Q P++ S + GP H +KL + ++ A ++E+ GG
Sbjct: 716 AKQYQIGDPLDRSTAH----------GPQNHLAHLNKLVEYVEKAVAGGAKVEV--GGKR 763
Query: 434 DKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGS 493
+ +G Y PTI+ + + S+E FGPI+ V + D EDV + T ++GL
Sbjct: 764 LEREGLYFPPTILSNIDDENFAASEESFGPIMCVSSFDDDDIEDVLRRANDT-EFGLAAG 822
Query: 494 IFARD-REAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNILNR 552
+F RD +++++A+ AG ++N V A FGG + SG G LN
Sbjct: 823 VFTRDSSKSLRVAE---ALHAGTVFVNTYQKTDVAAP--FGGFKQSGFGKDMGE-EALNE 876
Query: 553 FVSVRNIKENY 563
++ + I Y
Sbjct: 877 YLVTKTITIEY 887
>7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 552
Score = 107 bits (266), Expect = 6e-23
Identities = 111/424 (26%), Positives = 186/424 (43%), Gaps = 41/424 (9%)
Query: 91 SEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKYRYDMLAAT 150
++V+ V +AT +++AA++++K+A W R V K LI K LA
Sbjct: 83 NQVVTRVPKATQAEMQAALESNKKAFRSWSNQSILTRQQVMFKLQALI--KENMGELAKN 140
Query: 151 MLG-QGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEYRPLE---G 206
+ QGK + AE D + L V++ + + Q E+ V + L G
Sbjct: 141 ITKEQGKTLADAEGDVLRGLQV-----VEHCCSIPSLQMGETVANVARDMDTYSLVLPLG 195
Query: 207 FVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNF 265
V PFNF A+ + A+ GNT++ KPS+ + LL+ +L EAG P GVVN
Sbjct: 196 VTAGVAPFNFPAMIPLWMFPVAITTGNTMLLKPSERVPGATMLLMELLNEAGCPPGVVNV 255
Query: 266 VPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKN 325
+ G + + E A+ F GS K +Y ++ NG R+ G KN
Sbjct: 256 IHGQH-DAVNFICDAPEIKAVSFVGSDQAGKYIY---ERAGKNG-----KRVQSNMGAKN 306
Query: 326 FHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVN 385
+I AN +++ AF GQ+C A S ++ + DL + Q +
Sbjct: 307 HGIILGDANKENTLNQLAGAAFGAAGQRCMALSTAVF-VGDAQAWIPDL---VERAQKLK 362
Query: 386 TSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFG------GFHDKSKGY 439
+A + G D +GPVI S ++ +I+ + I+ G G+ D GY
Sbjct: 363 VNAGHVPGTD----VGPVISAASRQRINDLIESGVKEGAKLILDGRKITVPGYED---GY 415
Query: 440 YIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDR 499
++ PTI+ P ++E FGP+L + + +D +V++ + YG ++F +
Sbjct: 416 FVGPTILSDVTPSMKCYTEEIFGPVLVILKAD--TLDDAIGIVNA-NPYGNGTAVFTTNG 472
Query: 500 EAIK 503
A +
Sbjct: 473 AAAR 476
>Hs4557343 [C] KOG2453 Aldehyde dehydrogenase
Length = 511
Score = 106 bits (265), Expect = 8e-23
Identities = 115/484 (23%), Positives = 208/484 (42%), Gaps = 30/484 (6%)
Query: 68 ERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYER 127
E +Y GG+ + PAN+ E +A V QA+ D + ++ +++A W +P +R
Sbjct: 24 EGVYNGSWGGRGEVITTYCPANN-EPIARVRQASVADYEETVKKAREAWKIWADIPAPKR 82
Query: 128 ASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQ 187
+ + D + K + + + L GK + + + + E D + V + +
Sbjct: 83 GEIVRQIGDALREKIQV-LGSLVSLEMGKILVEG-VGEVQEYVDICDYAVGLSRMIGGPI 140
Query: 188 PIESSPGVWNRAEYRPLEGFVYAVTPFNF-TAIAGNLIGAPALMGNTVVWKPSQNANLSN 246
G ++ P+ G V +T FNF A+ G + GN +WK + +L +
Sbjct: 141 LPSERSGHALIEQWNPV-GLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLIS 199
Query: 247 Y----LLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDI 302
++ VLE+ LP + + G A ++ + D L FTGST V KQ+ +
Sbjct: 200 VAVTKIIAKVLEDNKLPGAICSLTCGGA-DIGTAMAKDERVNLLSFTGSTQVGKQVGLMV 258
Query: 303 QKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYL 362
Q+ + R + E GG N + A++ V S L A GQ+C+ R+++
Sbjct: 259 QER--------FGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFI 310
Query: 363 PESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKND 422
ES +E L ++++ N D + GP+ + + +++AK +
Sbjct: 311 HESIHDEVVNRLKKAYAQIRVGNP-------WDPNVLYGPLHTKQAVSMFLGAVEEAKKE 363
Query: 423 PELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELV 482
+V+GG G Y++PTI+ E F PIL V+++ K E+
Sbjct: 364 GG-TVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKF---KNEEEVFAW 419
Query: 483 DSTSQYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTND 542
++ + GL+ SIF +D I G +N ++GA + FGG + +G
Sbjct: 420 NNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGA-FGGEKHTGGGR 478
Query: 543 KAGS 546
++GS
Sbjct: 479 ESGS 482
>CE24573 [C] KOG2450 Aldehyde dehydrogenase
Length = 574
Score = 104 bits (259), Expect = 4e-22
Identities = 121/459 (26%), Positives = 200/459 (43%), Gaps = 39/459 (8%)
Query: 92 EVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKYRYDMLAATM 151
+V+A +AT + V ++A+ A+ W + +R V K ADLI ++ ++ +
Sbjct: 113 QVVAKCPKATADIVDQYVKAAADAQSAWGETTALDRGKVLHKVADLI-REHAEEIAIWEV 171
Query: 152 LGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEYRPLE--GFVY 209
GK +Y+A D I AD F F A + +E G R Y E G V
Sbjct: 172 KTNGKPIYEARCD-IASSADTFDFFGGIATAVLQGDSLELPGGPSQRIAYTRREPYGVVG 230
Query: 210 AVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPG 268
+ +N+ APAL GN VV+KPS A S LL +L AG+P GV N + G
Sbjct: 231 CIGAWNYPFQTCVWKVAPALAAGNAVVYKPSPFAPASPVLLGEILTAAGVPKGVYNVIQG 290
Query: 269 NAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHL 328
E + + A + FTGS A + +Q+ ++ + E GGK+ +
Sbjct: 291 EQ-EAGVALCEHNLVAKVSFTGSVASGEA----VQRQAAT---KNVKPVTLELGGKSEII 342
Query: 329 IHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSA 388
I +++ +V S + F QGQ C+ +RV++ + F + VQ N
Sbjct: 343 IFDDSDVKSAVASAMLANFLNQGQVCTNATRVFVQKGILASFTEAI------VQEAN--- 393
Query: 389 SKINGGD---LHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFH----DKSKGYYI 441
K+ GD +G I+EG ++ ++ AK + + ++ GG G Y
Sbjct: 394 DKLKVGDPLLEDTRVGANINEGHLQRILGYVESAKQEGGV-VLRGGVRVHPTGVEGGAYF 452
Query: 442 QPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARD-RE 500
+P II + + +E FG ++ + P E+V ++T+ YGL +F+ +
Sbjct: 453 EPAIITGLSDEARAVREEIFGAVMLI--LPFETEEEVIARANNTT-YGLAAGVFSGNLAR 509
Query: 501 AIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSG 539
++A + AG +IN + V FGG + SG
Sbjct: 510 GHRVA---ARLQAGTVFINTYNDTEVNVP--FGGFKNSG 543
>CE01232 [C] KOG2453 Aldehyde dehydrogenase
Length = 514
Score = 104 bits (259), Expect = 4e-22
Identities = 113/494 (22%), Positives = 221/494 (43%), Gaps = 32/494 (6%)
Query: 60 DVPLVINGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQAKDKW 119
++ L N +++ + Q PAN+S + ANV +D + AI +K+A + W
Sbjct: 17 ELGLTENNAGVFHGKWAASGQVVQSFAPANNSPI-ANVQNGNVQDYEIAISEAKKAYNDW 75
Query: 120 YKLPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKY 179
++P R + + D + T+ + ++ L GK + + + E D +
Sbjct: 76 CEVPAPRRGEIVRQIGDKLRTQLQ-NLGKLVSLEMGK-ISAEGVGEVQEYVDICDYATGL 133
Query: 180 ANELYAQQPIESSPGVWNRAEYRPLEGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKP 238
+ L + PG ++ PL G V ++ FNF A AL+ GN+VVWKP
Sbjct: 134 SRSLEGKIFPSERPGHALLEQWNPL-GVVGVISAFNFPCAVYGWNNALALVTGNSVVWKP 192
Query: 239 SQNANLSNYLLLTVLEEAGLPNGV----VNFVPGNAVEVTKEVLSDSEFAALHFTGSTAV 294
+ + L+ + ++EE + N V + V G +V + ++ D + FTGS+ +
Sbjct: 193 APSTPLTAIAVTKLVEEVLVANNVNPALCSLVCGEG-DVGQALVKDKRVNLVSFTGSSEI 251
Query: 295 FKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKC 354
K + +Q + +++ E GG N +++ A++ V +T+ A GQ+C
Sbjct: 252 GKIVGQQVQ--------ARFGKLLLELGGNNAIIVNEDADLNMVVPATVFAAVGTAGQRC 303
Query: 355 SATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGG-DLHGFIGPVIHEGSFDKL- 412
+ T R+ + + ++ L ++ + S+I D + IGP+ ++ + K
Sbjct: 304 TTTRRLIVHDKVYDQVLERLKKAYAQFE------SRIGCPLDSNTIIGPLHNQQAVGKYK 357
Query: 413 AKVIDDAKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPD 472
A V + + ++E +GG + G ++ PTI+ P + +E F PIL V ++
Sbjct: 358 ASVAEAVASGGKIE--YGGKVLERDGNFVLPTIVTGLKHDSPVVLRETFAPILYVLKF-- 413
Query: 473 AKFEDVCELVDSTSQYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWF 532
+ E+ + + Q GL+ S+F + + + G +N ++GA + F
Sbjct: 414 STLEEAIAINNEVDQ-GLSSSLFTTNIQNVFKWMGPKGSDCGIVNVNIPTSGAEIGGA-F 471
Query: 533 GGARMSGTNDKAGS 546
GG + +G ++GS
Sbjct: 472 GGEKETGGGRESGS 485
>7293810 [C] KOG2453 Aldehyde dehydrogenase
Length = 594
Score = 102 bits (255), Expect = 1e-21
Identities = 114/461 (24%), Positives = 208/461 (44%), Gaps = 34/461 (7%)
Query: 94 LANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKYRYDMLAATMLG 153
+A V Q ++++ I + +A +W ++P R + + D + KY+ + L
Sbjct: 129 IAKVRQGNVQELEHTIGLAVEAYKQWRQVPAPVRGEIVRQIGDEL-RKYKEPLGKLVSLE 187
Query: 154 QGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAE-YRPLEGFVYAVT 212
GK +Y + E D + V + +Y+ Q I S + E +RPL G V ++
Sbjct: 188 VGK-IYSEGQGEVQEFIDICDYAVGLSR-IYSGQLINSERADHSILEAWRPL-GVVGVIS 244
Query: 213 PFNF-TAIAGNLIGAPALMGNTVVWKPSQNANL----SNYLLLTVLEEAGLPNGVVNFVP 267
+NF A+ G GN+V+WK + + L + ++ VL LP VV
Sbjct: 245 AYNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPP-VVTLCQ 303
Query: 268 GNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFH 327
G +V + +++D + FTGS + + ++Q R + +++ E GG N
Sbjct: 304 GGT-DVGQTLVADKRVNLVSFTGSCQTGRDVGVEVQ--------RRFGKVILELGGNNAL 354
Query: 328 LIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNTS 387
+I SAN+ ++ + L G GQ+C+ T R+ + E ++F ++L G ++
Sbjct: 355 IIDESANVKMALDAALFGCIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQL------ 408
Query: 388 ASKINGG-DLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYIQPTII 446
SKI + +GPV + + + I +AK+ + FGG + G+Y++PT+I
Sbjct: 409 ISKIGHQLEAQTLVGPVHTQQNVENYKAAIAEAKSLGG-TVAFGGNVIQRDGFYVEPTVI 467
Query: 447 KTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARD-REAIKIA 505
+ +E F PI+ + + AK D ++ + GL+ +IF + +A K
Sbjct: 468 TGLPHDASVVHRETFAPIVYILK---AKNVDQAIEWNNEVEQGLSSAIFTENIGQAFKWI 524
Query: 506 DEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGS 546
K G IN + GA + FGG + +G ++GS
Sbjct: 525 GAK-GSDCGIVNINTTTNGAEIGGA-FGGEKATGGGRESGS 563
>At2g24270 [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 96.3 bits (238), Expect = 1e-19
Identities = 115/467 (24%), Positives = 204/467 (43%), Gaps = 64/467 (13%)
Query: 64 VINGERIYYNDDG-------GKRGIFQQLNPANHSEVLANVTQATNEDVKAAIQASKQAK 116
+++GE Y DG GK +NPA + V T E+V A ++ +K A+
Sbjct: 10 ILDGEVYKYYADGEWKTSSSGKSVAI--MNPATR-KTQYKVQACTQEEVNAVMELAKSAQ 66
Query: 117 DKWYKLPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITEL---ADFF 173
W K P ++RA + KAA ++ K +A +++ K + + D +TE+ D
Sbjct: 67 KSWAKTPLWKRAELLHKAAAIL--KDNKAPMAESLV---KEIAKPAKDSVTEVVRSGDLI 121
Query: 174 RFNVKYANELYAQQPI---ESSPGVWNRAEY-----RPLEGFVYAVTPFNFTA-IAGNLI 224
+ + + + +S PG +R +Y PL G V A+ PFN+ +A + I
Sbjct: 122 SYCAEEGVRILGEGKFLLSDSFPGN-DRTKYCLTSKIPL-GVVLAIPPFNYPVNLAVSKI 179
Query: 225 GAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFA 284
+ GN++V KP +S ++ AG P G+++ + G E+ +
Sbjct: 180 APALIAGNSLVLKPPTQGAVSCLHMVHCFHLAGFPKGLISCITGKGSEIGDFLTMHPAVN 239
Query: 285 ALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLR 344
+ FTG GD G+ + E GGK+ ++ A++ + ++
Sbjct: 240 CISFTG---------GD--TGISISKKAGMIPLQMELGGKDACIVLDDADLDLVASNIIK 288
Query: 345 GAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGG--DLHGFIGP 402
G F + GQ+C+A V + ES ++E V+ V +K+ G + + I
Sbjct: 289 GGFSYSGQRCTAVKVVLVMESVADEL----------VEKVKAKVAKLTVGPPEENSDITA 338
Query: 403 VIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFG 462
V+ E S + + ++ DAK E F + K +G I P ++ P +E FG
Sbjct: 339 VVSESSANFIEGLVMDAK---EKGATFCQEY-KREGNLIWPLLLDNVRPDMRIAWEEPFG 394
Query: 463 PILTVYEYPDAKFEDVCELVD--STSQYGLTGSIFARD-REAIKIAD 506
P++ P + V E ++ + S +GL G +F +D +AI I+D
Sbjct: 395 PVV-----PVLRINSVEEGINHCNASNFGLQGCVFTKDINKAILISD 436
>SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase
Length = 498
Score = 95.1 bits (235), Expect = 3e-19
Identities = 113/474 (23%), Positives = 198/474 (40%), Gaps = 34/474 (7%)
Query: 91 SEVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKYRYDMLAAT 150
+E LA VT + E+ + AI+ + +A + ER ++ + DLI D+
Sbjct: 49 NETLAPVTDMSVEETRKAIKVAHEAFLSYRNSDIKERYAILRRWYDLIMENAD-DLATMM 107
Query: 151 MLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEYRPLEGFVYA 210
L GK + A+ + + A F + A + + S+P +P+ G V
Sbjct: 108 TLENGKALGDAKGE-VVYAAKFIDWFAGEALRISGDSSMSSNPQNRIITIKQPV-GVVGI 165
Query: 211 VTPFNF-TAIAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPGN 269
+TP+NF A+ +GA G TVV +P+ + L + E AG+P GV+N V N
Sbjct: 166 ITPWNFPAAMITRKVGAALAAGCTVVIRPAAETPFTALALAKLAERAGVPAGVLNMVTAN 225
Query: 270 A-VEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHL 328
+ E E+ ++ + FTGST V K L + ++ E GG +
Sbjct: 226 SPSEHGIELTTNPLIRKVSFTGSTNVGKILAKQSSSTL--------KKLSLELGGNAPFI 277
Query: 329 IHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSA 388
+ A++ + + + F GQ C +R+Y+ S + F V V
Sbjct: 278 VFEDADLEKAADALMACKFRGSGQTCVCANRIYVHSSVYDAF----------VDLVTERV 327
Query: 389 SKIN---GGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYIQPTI 445
SK G D GP+I E + K+ + ++DA + + G Y +PT+
Sbjct: 328 SKFKLGYGLDAGVTHGPLISEKAISKVKQHVEDAVQKGGVVVTGGKVASNLGPMYFEPTV 387
Query: 446 IKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDREAIKIA 505
I +E FGP+ ++++ ED + S GL G +F++D +
Sbjct: 388 IINAKQGMLISEEETFGPVGALFKFDT---EDEVVAWANDSPVGLAGYLFSKDISRVFRV 444
Query: 506 DEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNILNRFVSVRNI 559
E L+ G N V++ FGG + SG + GS ++ ++ ++++
Sbjct: 445 GEALQ--VGMVGCNTGLVSDVLSP--FGGVKESGFG-REGSKYGISEYLDIKSL 493
>YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G
Length = 644
Score = 90.5 bits (223), Expect = 6e-18
Identities = 118/486 (24%), Positives = 191/486 (39%), Gaps = 54/486 (11%)
Query: 92 EVLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKYRYDMLAATM 151
+ L + T D+ + + +A+ W + R V D I D++A
Sbjct: 121 QYLGSFPSKTEADIDEMVSKAGKAQSTWGNSDFSRRLRVLASLHDYILNNQ--DLIARVA 178
Query: 152 L-GQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWN---------RAEY 201
GK + A + I + ++ +K+ A QP PG N Y
Sbjct: 179 CRDSGKTMLDASMGEILVTLEKIQWTIKHGQR--ALQP-SRRPGPTNFFMKWYKGAEIRY 235
Query: 202 RPLEGFVYAVTPFNFTAIAGNLIG---APALMGNTVVWKPSQNANLSNYLLLTVL----- 253
PL G + ++ +N+ NL+G A GN +V K S+ S+ + ++
Sbjct: 236 EPL-GVISSIVSWNYPF--HNLLGPIIAALFTGNAIVVKCSEQVVWSSEFFVELIRKCLE 292
Query: 254 ---EEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGL 310
E+ L P + S F + F GS V + K +
Sbjct: 293 ACDEDPDLVQLCYCLPPTENDDSANYFTSHPGFKHITFIGSQPVAHYILKCAAKSLTP-- 350
Query: 311 YRDYPRIVGETGGKNFHLIHPSANIPHSVLSTL-RGAFEFQGQKCSATSRVYLPESKSEE 369
+V E GGK+ ++ SA ++ S + RG F+ GQ C RV + S+E
Sbjct: 351 ------VVVELGGKDAFIVLDSAKNLDALSSIIMRGTFQSSGQNCIGIERVIV----SKE 400
Query: 370 FFRDLGGVLSEVQPVNTSASKINGGDLHGF-IGPVIHEGSFDKLAKVIDDAKNDPELEIV 428
+ DL +L++ N + L +G +I + FD+L ++ DA ++
Sbjct: 401 NYDDLVKILNDRMTANPLRQGSDIDHLENVDMGAMISDNRFDELEALVKDAVAKGA-RLL 459
Query: 429 FGGFHDKS----KGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDS 484
GG K +G+Y QPT++ P E FGPIL + + AK D C + +
Sbjct: 460 QGGSRFKHPKYPQGHYFQPTLLVDVTPEMKIAQNEVFGPILVMMK---AKNTDHCVQLAN 516
Query: 485 TSQYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKA 544
++ +GL GS+F D + L+ GN IND +T V Q FGG SG
Sbjct: 517 SAPFGLGGSVFGADIKECNYVANSLQ--TGNVAINDFAT-FYVCQLPFGGINGSGYGKFG 573
Query: 545 GSGNIL 550
G +L
Sbjct: 574 GEEGLL 579
>At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 578
Score = 88.2 bits (217), Expect = 3e-17
Identities = 97/384 (25%), Positives = 170/384 (44%), Gaps = 38/384 (9%)
Query: 197 NRAEYRPLEGFVYAVTPFN--FTAIAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLE 254
+R E+ PL G + A+ P+N F I ++ A GN +V K S++A+ S +++
Sbjct: 182 SRVEFHPL-GVIGAIVPWNYPFHNIFNPMLAA-VFSGNGIVIKVSEHASWSGCFYFRIIQ 239
Query: 255 EA----GLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGL 310
A G P +V+ + G A T E L S + F GSTAV K + + + +
Sbjct: 240 AALAAVGAPENLVDVITGFAE--TGEALVSSVDKMI-FVGSTAVGKMIMRNAAETLTP-- 294
Query: 311 YRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEF 370
+ E GGK+ +I A++ H +RG + GQ C+ R Y+ + F
Sbjct: 295 ------VTLELGGKDAFIICEDADVSHVAQVAVRGTLQSSGQNCAGAERFYVHKDIYTAF 348
Query: 371 FRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIV-- 428
+G V V+ V+ D+ G + + + L +++DA D EI
Sbjct: 349 ---IGQVTKIVKSVSAGPPLTGRYDM----GAICLQEHSEHLQSLVNDAL-DKGAEIAVR 400
Query: 429 --FGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTS 486
FG + + Y PT++ N + +E FGPI+ + ++ + E+V +L + S
Sbjct: 401 GSFGHLGEDAVDQYFPPTVLINVNHNMKIMKEEAFGPIMPIMQF--STDEEVIKLAND-S 457
Query: 487 QYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGS 546
+Y L ++F+ + K +++ G IND ++ + FGG + SG AG
Sbjct: 458 RYALGCAVFSGSKHRAKQIASQIQ--CGVAAINDFASNYMCQSLPFGGVKDSGFGRFAGI 515
Query: 547 GNILNRFV--SVRNIKENYYELTD 568
+ + SV + EN +E +
Sbjct: 516 EGLRACCLVKSVYPVAENAFEFQE 539
>YMR110c [C] KOG2456 Aldehyde dehydrogenase
Length = 532
Score = 80.5 bits (197), Expect = 6e-15
Identities = 96/376 (25%), Positives = 153/376 (40%), Gaps = 30/376 (7%)
Query: 206 GFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVN 264
G V + PFNF + A AL GNT+V KPS+ + ++ +L AG P+G++
Sbjct: 130 GSVLIIAPFNFPLLLAFAPLAAALAAGNTIVLKPSELTPHTAVVMENLLTTAGFPDGLIQ 189
Query: 265 FVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGK 324
V G A++ T +L +F + +TGS V G I V + V E GGK
Sbjct: 190 VVQG-AIDETTRLLDCGKFDLIFYTGSPRV-----GSI---VAEKAAKSLTPCVLELGGK 240
Query: 325 NFHLI---HPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEV 381
+ I ++NI ++ GAF GQ C + + + +S + ++ VL+E
Sbjct: 241 SPTFITENFKASNIKIALKRIFFGAFGNSGQICVSPDYLLVHKSIYPKVIKECESVLNEF 300
Query: 382 QPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYI 441
P D +IHE ++ K I+ + D +
Sbjct: 301 YP---------SFDEQTDFTRMIHEPAYKKAVASINSTNGSKIVPSKISINSDTEDLCLV 351
Query: 442 QPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDREA 501
PTI+ P + QE F P+L + EY D ++ + L IF+ +
Sbjct: 352 PPTIVYNIGWDDPLMKQENFAPVLPIIEYED--LDETINKIIEEHDTPLVQYIFSDSQTE 409
Query: 502 IKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAGSGNILNRFVSVRNI-K 560
I +L+ +G+ + D + FGG SG + G N F R I K
Sbjct: 410 INRILTRLR--SGDCVVGDTVIHVGITDAPFGGIGTSGYGNYGGYYG-FNTFSHERTIFK 466
Query: 561 ENYY-ELTDY-RYPSN 574
+ Y+ + T + RYP N
Sbjct: 467 QPYWNDFTLFMRYPPN 482
>YBR006w [C] KOG2451 Aldehyde dehydrogenase
Length = 497
Score = 79.0 bits (193), Expect = 2e-14
Identities = 103/472 (21%), Positives = 196/472 (40%), Gaps = 40/472 (8%)
Query: 50 SLSKFKNSSLDVPLV------INGERIYYNDDGGKRGIFQQLNPANHSEVLANVTQATNE 103
+LSK+ +L+ P + I+G+ + D+ +F+ ++PA+ E++A V +
Sbjct: 2 TLSKYSKPTLNDPNLFRESGYIDGKWVKGTDE-----VFEVVDPAS-GEIIARVPEQPVS 55
Query: 104 DVKAAIQASKQAKDKWYKLPYYERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEI 163
V+ AI + + + ERA +L+ D+ L GK + +A+
Sbjct: 56 VVEEAIDVAYETFKTYKNTTPRERAKWLRNMYNLMLENLD-DLATIITLENGKALGEAKG 114
Query: 164 DCITELADFFRFNVKYANELYAQ--QPIESSPGVWNRAEYRPLEGFVYAVTPFNF-TAIA 220
+ I A +F + + A LY QP+ V+ R G + P+NF +A+
Sbjct: 115 E-IKYAASYFEWYAEEAPRLYGATIQPLNPHNRVFT---IRQPVGVCGIICPWNFPSAMI 170
Query: 221 GNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFV--PGNAVEVTKEVL 278
A +G TVV KP LS + + E+AG P G N + N ++ K +
Sbjct: 171 TRKAAAALAVGCTVVIKPDSQTPLSALAMAYLAEKAGFPKGSFNVILSHANTPKLGKTLC 230
Query: 279 SDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHS 338
+ + FTGST V K L + ++ E GG ++ A++ +
Sbjct: 231 ESPKVKKVTFTGSTNVGKILMKQSSSTL--------KKLSFELGGNAPFIVFEDADLDQA 282
Query: 339 VLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHG 398
+ + F GQ C +R+Y+ S ++F + +L+E ++ HG
Sbjct: 283 LEQAMACKFRGLGQTCVCANRLYVHSSIIDKFAK----LLAERVKKFVIGHGLDPKTTHG 338
Query: 399 FIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQ 458
VI+ + +K+ + DA + ++ GG + + P I+ +
Sbjct: 339 C---VINSSAIEKVERHKQDAIDKGAKVVLEGGRLTELGPNFYAPVILSHVPSTAIVSKE 395
Query: 459 EFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDREAIKIADEKLK 510
E FGP+ ++ + E+V + T ++GL +F+++ + E L+
Sbjct: 396 ETFGPLCPIFSFD--TMEEVVGYANDT-EFGLAAYVFSKNVNTLYTVSEALE 444
>7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 816
Score = 78.6 bits (192), Expect = 2e-14
Identities = 92/383 (24%), Positives = 166/383 (43%), Gaps = 30/383 (7%)
Query: 36 FGSKDLVDWDLLRASLSKFKNSSLDVPLVINGERIYYNDDGGKRGIFQQLNPANHSEVLA 95
FG++ L D++ +K + + L INGE + D + + +NP N EVL
Sbjct: 406 FGNQQL-DFEAFTLKANK-REIRVPTQLFINGEFV----DAEAQRTLEIVNPTNE-EVLC 458
Query: 96 NVTQATNEDVKAAIQASKQA-KDKWYKLPYYERASVFMKAADLICTKYRYDMLAATMLGQ 154
V A+ DV A++A+ A W ++ +R + + ADL+ + + LA
Sbjct: 459 KVACASATDVDKAVRAAHSAFYGSWRQITPRQRGQLMLNLADLM--ERNKEELATIESVD 516
Query: 155 GKNVYQAEIDCITELA-DFFRFNVKYANELYAQQ-PIESSP--GVWNRAEYRPLEGFVYA 210
VY + ++ + +R+ + +++ P+ + V P+ G
Sbjct: 517 SGAVYTLALKTHVGMSIEAWRYFAGWCDKIQGNTIPVNPARPNNVLTFTRKEPI-GVCGL 575
Query: 211 VTPFNFTAIAGNL-IGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPGN 269
+TP+N+ + + + A GNT + KP+Q L+ + AG P GV+N +PG
Sbjct: 576 ITPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRAGFPPGVINVLPGK 635
Query: 270 AVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLI 329
+ + V L FTGST + K I K + + + E GGK+ +I
Sbjct: 636 GSDAGQAVADHELVRKLGFTGSTPIGKH----IMKSCADS---NLKKCSLELGGKSPLII 688
Query: 330 HPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSAS 389
++ +V + F +G+ C A R+++ + +EF R VL +++ + T
Sbjct: 689 FADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEFIR---RVLKDLRTM-TIGD 744
Query: 390 KINGGDLHGFIGPVIHEGSFDKL 412
++ H GP H+ FDKL
Sbjct: 745 PLDRSTAH---GPQNHKAHFDKL 764
>SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 522
Score = 73.2 bits (178), Expect = 1e-12
Identities = 105/470 (22%), Positives = 191/470 (40%), Gaps = 47/470 (10%)
Query: 93 VLANVTQATNEDVKAAIQASKQAKDKWYKLPYYERASVFMKAA--DLICTKYRYDMLAAT 150
+L V D+ +I +++A+ +W + ER + F+KA ++I + +Y +A
Sbjct: 15 LLGEVKLFNKSDIDQSIILAEEAQKEWKSTSFAERRN-FLKALKENIIRNQDKYAEIACK 73
Query: 151 MLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNR-----AEYRPLE 205
GK + A I L + N AN + +P + + +Y PL
Sbjct: 74 --DTGKTLVDAAFGEI--LVTLEKINWTLANGEQSLRPTKRPNSLLTSYKGGYVKYEPL- 128
Query: 206 GFVYAVTPFNFTA--IAGNLIGAPALMGNTVVWKPSQNANLSNY----LLLTVLEEAGLP 259
G + A+ +N+ G +I A GN +V K S+ S + ++ ++L+ G
Sbjct: 129 GVIAALVSWNYPLHNALGPIISA-LFAGNAIVVKGSELTAWSTHQYCEMVRSLLQSMGHS 187
Query: 260 NGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVG 319
+V + +V + S S + F GS + K + K + +
Sbjct: 188 PELVQCITC-LPDVADHLTSHSGIKHITFIGSQPIAKLVAASAAKQLTP--------LCL 238
Query: 320 ETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLS 379
E GGK+ ++ + + +RG F+ GQ C R+ + + L +S
Sbjct: 239 ELGGKDPCILTDDHRLEEILSIVMRGVFQSAGQNCIGIERIIALDGVYDTIITKLYNRIS 298
Query: 380 EVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGF---HDK- 435
++ + + ++ +G ++ FD L +I DA + +V+GG H K
Sbjct: 299 TMRLGMYTQNDVD-------MGAMVSNNRFDHLESLIQDAVS-KGARLVYGGHRFQHPKY 350
Query: 436 SKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIF 495
KG Y PT++ +E F PI V+ E E+ + T ++GL S+F
Sbjct: 351 PKGNYFLPTLLVDATNEMKIAQEECFAPIALVFRAKSP--EHALEIANGT-EFGLGASVF 407
Query: 496 ARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAG 545
RD++ + + L+ G +ND + Q FGG + SG AG
Sbjct: 408 GRDKQLCQYFTDNLE--TGMVAVNDFG-AFYLLQMPFGGCKKSGYGRFAG 454
>HsM4502035 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 71.2 bits (173), Expect = 4e-12
Identities = 93/420 (22%), Positives = 166/420 (39%), Gaps = 40/420 (9%)
Query: 132 MKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIES 191
++A + + +++ A KN + A + + + + + ++ E A +P+E
Sbjct: 30 LEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEK 89
Query: 192 SPGVWNRAEYRPLE--GFVYAVTPFN--FTAIAGNLIGAPALMGNTVVWKPSQNANLSNY 247
+P Y E G V + +N F ++GA A GN VV KPS+ +
Sbjct: 90 TPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAA-GNAVVLKPSELSENMAS 148
Query: 248 LLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVV 307
LL T++ + L + + G E T+ L F + +TGST V K ++
Sbjct: 149 LLATIIPQY-LDKDLYPVINGGVPETTE--LLKERFDHILYTGSTGVGKI--------IM 197
Query: 308 NGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKS 367
+ + E GGK+ + + ++ + G F GQ C A + S
Sbjct: 198 TAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQ 257
Query: 368 EEFFRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEI 427
+ L L E + S+ G +I F ++ +I+ K +
Sbjct: 258 NQIVEKLKKSLKEFYGEDAKKSRD--------YGRIISARHFQRVMGLIEGQK------V 303
Query: 428 VFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQ 487
+GG D + Y I PTI+ +P+ P + +E FGP+L + E+ + ++ +
Sbjct: 304 AYGGTGDAATRY-IAPTILTDVDPQSPVMQEEIFGPVLPIVCV--RSLEEAIQFINQREK 360
Query: 488 YGLTGSIFARDREAIK--IADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAG 545
L +F+ + + IK IA+ S+G ND + FGG SG G
Sbjct: 361 -PLALYMFSSNDKVIKKMIAET----SSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHG 415
>Hs21359829 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 71.2 bits (173), Expect = 4e-12
Identities = 93/420 (22%), Positives = 166/420 (39%), Gaps = 40/420 (9%)
Query: 132 MKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIES 191
++A + + +++ A KN + A + + + + + ++ E A +P+E
Sbjct: 30 LEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEK 89
Query: 192 SPGVWNRAEYRPLE--GFVYAVTPFN--FTAIAGNLIGAPALMGNTVVWKPSQNANLSNY 247
+P Y E G V + +N F ++GA A GN VV KPS+ +
Sbjct: 90 TPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAA-GNAVVLKPSELSENMAS 148
Query: 248 LLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVV 307
LL T++ + L + + G E T+ L F + +TGST V K ++
Sbjct: 149 LLATIIPQY-LDKDLYPVINGGVPETTE--LLKERFDHILYTGSTGVGKI--------IM 197
Query: 308 NGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKS 367
+ + E GGK+ + + ++ + G F GQ C A + S
Sbjct: 198 TAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQ 257
Query: 368 EEFFRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEI 427
+ L L E + S+ G +I F ++ +I+ K +
Sbjct: 258 NQIVEKLKKSLKEFYGEDAKKSRD--------YGRIISARHFQRVMGLIEGQK------V 303
Query: 428 VFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQ 487
+GG D + Y I PTI+ +P+ P + +E FGP+L + E+ + ++ +
Sbjct: 304 AYGGTGDAATRY-IAPTILTDVDPQSPVMQEEIFGPVLPIVCV--RSLEEAIQFINQREK 360
Query: 488 YGLTGSIFARDREAIK--IADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTNDKAG 545
L +F+ + + IK IA+ S+G ND + FGG SG G
Sbjct: 361 -PLALYMFSSNDKVIKKMIAET----SSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHG 415
>CE13415 [C] KOG2456 Aldehyde dehydrogenase
Length = 437
Score = 69.3 bits (168), Expect = 1e-11
Identities = 78/338 (23%), Positives = 137/338 (40%), Gaps = 33/338 (9%)
Query: 205 EGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVV 263
+G V ++P+N+ L P++ GNT+V KPS+ + + L ++ + P V
Sbjct: 105 KGVVLVISPWNYPVSMVLLPMIPSIAAGNTIVIKPSELSENTAILFEKLIPKYFDPK-YV 163
Query: 264 NFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGG 323
V G E T+ L F + +TG V K + K + + E GG
Sbjct: 164 TIVNGGIPETTE--LLKERFDHIIYTGCPPVAKIIMAAAAKHLTP--------VTLELGG 213
Query: 324 KNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEVQP 383
K ++ A+I S RG + GQ C A + + + +F + L E
Sbjct: 214 KCPVVVEDDADIEISAQRIARGKWLNCGQTCLAPDYILVSSATKPKFVAAIQKCLKEFYG 273
Query: 384 VNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYIQP 443
N SK VI++ FD+++ ++D++K ++ G + + P
Sbjct: 274 GNAKESK--------DYSRVINQRHFDRISALLDESKG----VVLAGNEESRDRSDRFIP 321
Query: 444 TIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVD--STSQYGLTGSIFARDREA 501
+ P++ E FGP+L P +++CE +D + + L IF +D
Sbjct: 322 PTVLDVEKTDPFMHDEIFGPVL-----PIITVKNLCESIDFINKGEKPLAAYIFTKDE-- 374
Query: 502 IKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSG 539
K+ + ++G +ND V FGG +SG
Sbjct: 375 AKVQRFLNETTSGGVTVNDVIMHVAVITLPFGGVGVSG 412
>At1g44170 [C] KOG2456 Aldehyde dehydrogenase
Length = 484
Score = 67.8 bits (164), Expect = 4e-11
Identities = 92/422 (21%), Positives = 179/422 (41%), Gaps = 37/422 (8%)
Query: 125 YERASVFMKAADLICTKYRYDMLAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELY 184
YE +K +IC + +++AA GK ++ + ++ L + + +K
Sbjct: 31 YEWRVTQLKKLMIICDNHEPEIVAALRDDLGKPELESSVYEVSLLRNSIKLALKQLKNWM 90
Query: 185 AQQPIESSPGVWNRAEYRPLE--GFVYAVTPFNFTAIAG--NLIGAPALMGNTVVWKPSQ 240
A + ++S + + E G V ++ +N+ + +IGA + GN VV KPS+
Sbjct: 91 APEKAKTSLTTFPASAEIVSEPLGVVLVISAWNYPFLLSIDPVIGAISA-GNAVVLKPSE 149
Query: 241 NANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYG 300
A S+ LL +LE+ L V V G E + L + ++ + +TGS+ + + +
Sbjct: 150 LAPASSALLTKLLEQY-LDPSAVRVVEGAVTETS--ALLEQKWDKIFYTGSSKIGRVIMA 206
Query: 301 DIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEF-QGQKCSATSR 359
K + +V E GGK+ ++ ++ +V + G + GQ C +
Sbjct: 207 AAAKHLT--------PVVLELGGKSPVVVDSDTDLKVTVRRIIVGKWGCNNGQACVSPDY 258
Query: 360 VYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDA 419
+ + + + + L + N SK + +++ FD+L+K++D+
Sbjct: 259 ILTTKEYAPKLIDAMKLELEKFYGKNPIESK--------DMSRIVNSNHFDRLSKLLDE- 309
Query: 420 KNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYP--DAKFED 477
+ +IV+GG D+ + I PTI+ +S+E FGP+L + + F+
Sbjct: 310 -KEVSDKIVYGGEKDR-ENLKIAPTILLDVPLDSLIMSEEIFGPLLPILTLNNLEESFDV 367
Query: 478 VCELVDSTSQYGLTGSIFARDREAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARM 537
+ + Y T + ++R A + SAG +ND + + FGG
Sbjct: 368 IRSRPKPLAAYLFTHNKKLKERFAATV-------SAGGIVVNDIAVHLALHTLPFGGVGE 420
Query: 538 SG 539
SG
Sbjct: 421 SG 422
>7304212 [C] KOG2456 Aldehyde dehydrogenase
Length = 561
Score = 59.7 bits (143), Expect = 1e-08
Identities = 64/243 (26%), Positives = 102/243 (41%), Gaps = 26/243 (10%)
Query: 231 GNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVNFVPGNAVEVTKEVLSDSEFAALHFTG 290
GN VV KPS+ A + V+ + L N V G E + L + F + +TG
Sbjct: 132 GNCVVIKPSEIAANCAKFIADVIPKY-LDNDCYPVVCGGPSETAE--LLNQRFDYIFYTG 188
Query: 291 STAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGKNFHLIHPSANIPHSVLSTLRGAFEFQ 350
ST V K ++ K + P + E GGK+ I S ++ +V L G
Sbjct: 189 STRVGKIIHAAANKYLT-------PTTL-ELGGKSPCYIDKSVDMRTAVKRILWGKLINC 240
Query: 351 GQKCSATSRVYLPESKSEEFFRDLGGVLSEVQPVNTSASKINGGDLHGFIGPVIHEGSFD 410
GQ C A + + E+F + VL E N +S + VI+ +F
Sbjct: 241 GQTCIAPDYILCSKEVQEKFIVEAKDVLKEWYGENIQSSPD--------LSRVINANNFQ 292
Query: 411 KLAKVIDDAKNDPELEIVFGGFHDKSKGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEY 470
+L ++ + + GG +D S+ + I+PTI+ P + +E FGPIL ++
Sbjct: 293 RLLGLMKSGR------VAVGGNYDASERF-IEPTILVDVKETDPIMEEEIFGPILPIFNV 345
Query: 471 PDA 473
A
Sbjct: 346 ESA 348
>CE27441 [C] KOG2456 Aldehyde dehydrogenase
Length = 493
Score = 58.9 bits (141), Expect = 2e-08
Identities = 81/339 (23%), Positives = 138/339 (39%), Gaps = 37/339 (10%)
Query: 205 EGFVYAVTPFNFTAIAGNLIGAPALM-GNTVVWKPSQNANLSNYLLLTV--LEEAGLPNG 261
+G V ++P+N+ L PA+ GNTVV KPS+ LS + T L +
Sbjct: 104 KGVVLIISPWNYPVSMILLPMVPAIAAGNTVVIKPSE---LSENVAATFEKLIPKYFESK 160
Query: 262 VVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGET 321
V V G E T L F + +TG V K ++ + + E
Sbjct: 161 YVTVVNGGIPETTD--LLKERFDHILYTGCPPVAKI--------IMTAAAKHLTPVTLEL 210
Query: 322 GGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEV 381
GGK ++ A+I S G + GQ C A + + + + + ++E
Sbjct: 211 GGKCPVVVEDDADIDISAKRIAWGKWLNCGQTCLAPDYILVNSTVKPKLVAAIRKYVNEF 270
Query: 382 QPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYI 441
+ ASK +I++ FD+++ ++D + ++ GG D++ YI
Sbjct: 271 YGEDVKASKD--------YARMINQRHFDRISGLLDKTQG----AVLIGGERDRAD-LYI 317
Query: 442 QPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDREA 501
PT++ P++ E FGP+L + F + E + + + L IF R+
Sbjct: 318 PPTVLDVEKS-DPFMHDEIFGPVLPIITV--QSFSESLEYI-ADGEKPLAAYIFTRNEAK 373
Query: 502 IK-IADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSG 539
+K + +E S+G +ND V FGG +SG
Sbjct: 374 VKRLLNET---SSGGVTVNDVLMHITVDTLPFGGVGVSG 409
>At5g62530 [C] KOG2451 Aldehyde dehydrogenase
Length = 563
Score = 58.5 bits (140), Expect = 3e-08
Identities = 91/366 (24%), Positives = 154/366 (41%), Gaps = 55/366 (15%)
Query: 201 YRPLEGFVYAVTPFNFTAIAG--NLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGL 258
YR G V VTPFNF L+GA MGN + K ++ ++ +L GL
Sbjct: 200 YRWPYGPVTIVTPFNFPLEIPLLQLMGA-LYMGNKPLLKVDSKVSIVMEQMMRLLHYCGL 258
Query: 259 PNGVVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIV 318
P V+F+ + + K +L + L FTGS+ V ++L D+ KG RI
Sbjct: 259 PAEDVDFINSDGKTMNKILLEANPRMTL-FTGSSRVAEKLALDL-KG----------RIR 306
Query: 319 GETGGKNFHLIHPSAN-IPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGV 377
E G ++ ++ P + + + A+ GQKCSA S +++ E+ S+
Sbjct: 307 LEDAGFDWKVLGPDVQEVDYVAWQCDQDAYACSGQKCSAQSMLFVHENWSK--------- 357
Query: 378 LSEVQPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKS- 436
V + A + DL IGPV+ + + + + +++ P +++FGG K+
Sbjct: 358 TPLVSKLKELAERRKLEDL--TIGPVL-TFTTEAMLEHMENLLQIPGSKLLFGGKELKNH 414
Query: 437 -----------KGYYIQPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDST 485
Y+ I N + +++E FGP V EY + V E ++
Sbjct: 415 SIPSIYGALEPTAVYVPIEEILKDNKTYELVTKEIFGPFQIVTEYKKDQLPLVLEALERM 474
Query: 486 SQYGLTGSIFARD----REAIKIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSGTN 541
+ LT ++ + D +E I + Y+ + ++TGA WFG A
Sbjct: 475 HAH-LTAAVVSNDPIFLQEVIGNSVNGTTYAG----LRGRTTGA-PQNHWFGPA-----G 523
Query: 542 DKAGSG 547
D G+G
Sbjct: 524 DPRGAG 529
>Hs4502043 [C] KOG2456 Aldehyde dehydrogenase
Length = 468
Score = 57.4 bits (137), Expect = 6e-08
Identities = 79/337 (23%), Positives = 132/337 (38%), Gaps = 36/337 (10%)
Query: 206 GFVYAVTPFNF--TAIAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVV 263
G V + P+N+ L+GA A GN VV KPS+ + +L VL + +
Sbjct: 106 GLVLIIAPWNYPLNLTLVPLVGALAA-GNCVVLKPSEISKNVEKILAEVLPQY-VDQSCF 163
Query: 264 NFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGG 323
V G E + L + F + FTGS V K V+ + + E GG
Sbjct: 164 AVVLGGPQETGQ--LLEHRFDYIFFTGSPRVGKI--------VMTAAAKHLTPVTLELGG 213
Query: 324 KNFHLIHPSANIPHSVLSTLRGAFEFQ-GQKCSATSRVYLPESKSEEFFRDLGGVLSEVQ 382
KN + + + P +V + + F GQ C A V E L ++
Sbjct: 214 KNPCYVDDNCD-PQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFY 272
Query: 383 PVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYIQ 442
+ +S +G +I++ F +L ++ + + GG D+S Y I
Sbjct: 273 GDDPQSSPN--------LGRIINQKQFQRLRALLGCGR------VAIGGQSDESDRY-IA 317
Query: 443 PTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDREAI 502
PT++ P + +E FGPIL P + + E ++ ++ +++A +
Sbjct: 318 PTVLVDVQEMEPVMQEEIFGPIL-----PIVNVQSLDEAIEFINRREKPLALYAFSNSSQ 372
Query: 503 KIADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSG 539
+ + S+G F ND +A FGG SG
Sbjct: 373 VVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGVGASG 409
>Hs4557303 [C] KOG2456 Aldehyde dehydrogenase
Length = 485
Score = 56.6 bits (135), Expect = 1e-07
Identities = 93/399 (23%), Positives = 157/399 (39%), Gaps = 43/399 (10%)
Query: 147 LAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEY---RP 203
+AA + NVY E+ + DF N+ E +P++ + Y +P
Sbjct: 45 IAADLCKSEFNVYSQEVITVLGEIDFMLENLP---EWVTAKPVKKNVLTMLDEAYIQPQP 101
Query: 204 LEGFVYAVTPFN--FTAIAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLPNG 261
L G V + +N F LIGA A GN V+ KPS+ + + +L +L + L
Sbjct: 102 L-GVVLIIGAWNYPFVLTIQPLIGAIAA-GNAVIIKPSELSENTAKILAKLLPQY-LDQD 158
Query: 262 VVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGET 321
+ + G E T+ L F + +TG+TAV K V+ + + E
Sbjct: 159 LYIVINGGVEETTE--LLKQRFDHIFYTGNTAVGKI--------VMEAAAKHLTPVTLEL 208
Query: 322 GGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEV 381
GGK+ I ++ G + GQ C A + S + + + E
Sbjct: 209 GGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEF 268
Query: 382 QPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYI 441
N S +I+ F ++ +++ K I FGG D++ Y I
Sbjct: 269 YGENIKESPD--------YERIINLRHFKRILSLLEGQK------IAFGGETDEATRY-I 313
Query: 442 QPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDREA 501
PT++ +P+ + +E FGPIL + P ++ ++ + L +F+ + +
Sbjct: 314 APTVLTDVDPKTKVMQEEIFGPILPI--VPVKNVDEAINFINEREK-PLALYVFSHNHKL 370
Query: 502 IK-IADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSG 539
IK + DE S+G ND + FGG SG
Sbjct: 371 IKRMIDET---SSGGVTGNDVIMHFTLNSFPFGGVGSSG 406
>Hs18603595 [C] KOG2456 Aldehyde dehydrogenase
Length = 508
Score = 56.6 bits (135), Expect = 1e-07
Identities = 93/399 (23%), Positives = 157/399 (39%), Gaps = 43/399 (10%)
Query: 147 LAATMLGQGKNVYQAEIDCITELADFFRFNVKYANELYAQQPIESSPGVWNRAEY---RP 203
+AA + NVY E+ + DF N+ E +P++ + Y +P
Sbjct: 45 IAADLCKSEFNVYSQEVITVLGEIDFMLENLP---EWVTAKPVKKNVLTMLDEAYIQPQP 101
Query: 204 LEGFVYAVTPFN--FTAIAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLPNG 261
L G V + +N F LIGA A GN V+ KPS+ + + +L +L + L
Sbjct: 102 L-GVVLIIGAWNYPFVLTIQPLIGAIAA-GNAVIIKPSELSENTAKILAKLLPQY-LDQD 158
Query: 262 VVNFVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGET 321
+ + G E T+ L F + +TG+TAV K V+ + + E
Sbjct: 159 LYIVINGGVEETTE--LLKQRFDHIFYTGNTAVGKI--------VMEAAAKHLTPVTLEL 208
Query: 322 GGKNFHLIHPSANIPHSVLSTLRGAFEFQGQKCSATSRVYLPESKSEEFFRDLGGVLSEV 381
GGK+ I ++ G + GQ C A + S + + + E
Sbjct: 209 GGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEF 268
Query: 382 QPVNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYI 441
N S +I+ F ++ +++ K I FGG D++ Y I
Sbjct: 269 YGENIKESPD--------YERIINLRHFKRILSLLEGQK------IAFGGETDEATRY-I 313
Query: 442 QPTIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDREA 501
PT++ +P+ + +E FGPIL + P ++ ++ + L +F+ + +
Sbjct: 314 APTVLTDVDPKTKVMQEEIFGPILPI--VPVKNVDEAINFINEREK-PLALYVFSHNHKL 370
Query: 502 IK-IADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSG 539
IK + DE S+G ND + FGG SG
Sbjct: 371 IKRMIDET---SSGGVTGNDVIMHFTLNSFPFGGVGSSG 406
>Hs4502045 [C] KOG2456 Aldehyde dehydrogenase
Length = 385
Score = 50.1 bits (118), Expect = 9e-06
Identities = 75/336 (22%), Positives = 130/336 (38%), Gaps = 34/336 (10%)
Query: 206 GFVYAVTPFNFTA-IAGNLIGAPALMGNTVVWKPSQNANLSNYLLLTVLEEAGLPNGVVN 264
G V + P+N+ + L+ GN VV KPS+ + + +L VL + L
Sbjct: 25 GLVLIIAPWNYPLNLTLVLLVGTLPAGNCVVLKPSEISQGTEKVLAEVLPQY-LDQSCFA 83
Query: 265 FVPGNAVEVTKEVLSDSEFAALHFTGSTAVFKQLYGDIQKGVVNGLYRDYPRIVGETGGK 324
V G E + L + + + FTGS V K V+ + + E GGK
Sbjct: 84 VVLGGPQETGQ--LLEHKLDYIFFTGSPRVGKI--------VMTAATKHLTPVTLELGGK 133
Query: 325 NFHLIHPSANIPHSVLSTLRGAFEFQ-GQKCSATSRVYLPESKSEEFFRDLGGVLSEVQP 383
N + + + P +V + + F GQ C A V E L ++
Sbjct: 134 NPCYVDDNCD-PQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYG 192
Query: 384 VNTSASKINGGDLHGFIGPVIHEGSFDKLAKVIDDAKNDPELEIVFGGFHDKSKGYYIQP 443
+ +S +G +I++ F +L ++ + + GG ++S Y I P
Sbjct: 193 DDPQSSPN--------LGRIINQKQFQRLRALLGCGR------VAIGGQSNESDRY-IAP 237
Query: 444 TIIKTTNPRHPYLSQEFFGPILTVYEYPDAKFEDVCELVDSTSQYGLTGSIFARDREAIK 503
T++ P + +E FGPIL P + V E + ++ +++A
Sbjct: 238 TVLVDVQETEPVMQEEIFGPIL-----PIVNVQSVDEAIKFINRQEKPLALYAFSNSRQV 292
Query: 504 IADEKLKYSAGNFYINDKSTGAVVAQQWFGGARMSG 539
+ + S+G+F N+ T + FGG SG
Sbjct: 293 VNQMLERTSSGSFGGNEGFTYISLLSVPFGGVGHSG 328
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.136 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,883,157
Number of Sequences: 60738
Number of extensions: 1613352
Number of successful extensions: 3703
Number of sequences better than 1.0e-05: 71
Number of HSP's better than 0.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 3504
Number of HSP's gapped (non-prelim): 74
length of query: 576
length of database: 30,389,216
effective HSP length: 112
effective length of query: 464
effective length of database: 23,586,560
effective search space: 10944163840
effective search space used: 10944163840
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)